ARE THE EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE A RISK FACTOR FOR CARDIAC ARRHYTHMIA? Kronik Obstrüktif Akciğer Hastalığı Alevlenmeleri Kardiyak Aritmi İçin Risk Faktörü müdür?
ARE THE EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE A RISK FACTOR FOR CARDIAC ARRHYTHMIA? Kronik Obstrüktif Akciğer Hastalığı Alevlenmeleri Kardiyak Aritmi İçin Risk Faktörü müdür?
Yazar: Kaya, Murtaza; Yıldırım, Harun; Çoşkun, Abdil; Aydın, Hasan; Genc, Esref; Kadıoğlu, Emine; Halıcı, Ali
Dergi: Bozok Tıp Dergisi, Vol. 14 No. 2, 2024
Anahtar kelimeler: Chest Diseases ; Göğüs Hastalıkları ; ARE THE EXACERBATIONS OF CHRONIC OBSTRUCTIVEPULMONARY DISEASE A RISK FACTOR FOR CARDIACARRHYTHMIA?,Kronik Obstrüktif Akciğer Hastalığı Alevlenmeleri KardiyakAritmi İçin Risk Faktörü müdür?,ARE THE EXACERBATIONS OF CHRONIC OBSTRUCTIVEPULMONARY DISEASE A RISK FACTOR FOR CARDIACARRHYTHMIA?Kronik Obstrüktif Akciğer Hastalığı Alevlenmeleri KardiyakAritmi İçin Risk Faktörü müdür?

Objective: Hypoxemia, hypercapnia, and increased automaticity during exacerbations contribute to abnormalatrial and ventricular repolarization in chronic obstructive pulmonary disease (COPD), raising the riskof arrhythmias. This study aimed to predict the likelihood of arrhythmias by analyzing electrocardiograms(ECGs) of patients experiencing COPD attacks.Material and Methods: A total of 120 patients (66 in the COPD group and 54 in the control group) wereincluded. Statistical analysis compared QT and QTc interval maximum (max), minimum (min), and dispersion(disp); T-wave peak to end (Tp-e) max, min, and disp; Tp-e max/QT max, Tp-e max/QTc max ratios; and Pwave max, min, and disp durations among patients.Results: Of the males in the study, 48 (64%) were in the COPD group and 27 (36%) in the control group, while18 (40%) of the females were in the COPD group and 27 (60%) in the control group. There were no significantdifferences in patient ages or levels of sodium and potassium (p = 0.189, 0.353, and 0.071). Significantdifferences were found in QT max and min between groups, while QT disp showed no significant difference(p < 0.001, p < 0.001, and p = 0.490). Tp-e max, min, and disp values differed significantly between the COPDand control groups (p = 0.041, p < 0.001, and p = 0.001, respectively). No significant difference was observedbetween groups in terms of P max duration (p = 0.442), but significant differences were found in P min anddisp durations (p = 0.003 and p < 0.001, respectively). Receiver operating characteristic analysis identified 30ms as the cutoff for both P disp and Tp-e disp values, showing a significant difference.Conclusion: This study is the first to detect increased dispersions of P wave and Tp-e intervals (without anincrease in QTc disp.) during the evaluation of atrial and ventricular arrhythmia risks during COPD acuteattacks.

Objective: Hypoxemia, hypercapnia, and increased automaticity during exacerbations contribute to abnormalatrial and ventricular repolarization in chronic obstructive pulmonary disease (COPD), raising the riskof arrhythmias. This study aimed to predict the likelihood of arrhythmias by analyzing electrocardiograms(ECGs) of patients experiencing COPD attacks.Material and Methods: A total of 120 patients (66 in the COPD group and 54 in the control group) wereincluded. Statistical analysis compared QT and QTc interval maximum (max), minimum (min), and dispersion(disp); T-wave peak to end (Tp-e) max, min, and disp; Tp-e max/QT max, Tp-e max/QTc max ratios; and Pwave max, min, and disp durations among patients.Results: Of the males in the study, 48 (64%) were in the COPD group and 27 (36%) in the control group, while18 (40%) of the females were in the COPD group and 27 (60%) in the control group. There were no significantdifferences in patient ages or levels of sodium and potassium (p = 0.189, 0.353, and 0.071). Significantdifferences were found in QT max and min between groups, while QT disp showed no significant difference(p < 0.001, p < 0.001, and p = 0.490). Tp-e max, min, and disp values differed significantly between the COPDand control groups (p = 0.041, p < 0.001, and p = 0.001, respectively). No significant difference was observedbetween groups in terms of P max duration (p = 0.442), but significant differences were found in P min anddisp durations (p = 0.003 and p < 0.001, respectively). Receiver operating characteristic analysis identified 30ms as the cutoff for both P disp and Tp-e disp values, showing a significant difference.Conclusion: This study is the first to detect increased dispersions of P wave and Tp-e intervals (without anincrease in QTc disp.) during the evaluation of atrial and ventricular arrhythmia risks during COPD acuteattacks.