Assessment of long term prognostic value of admission vitamin D level in patients with acute STEMI undergoing primary percutaneous coronary intervention
Assessment of long term prognostic value of admission vitamin D level in patients with acute STEMI undergoing primary percutaneous coronary intervention
Yazar: Satilmisoglu, Muhammet Hulusi; Gul, Mehmet; Cakmak, Huseyin Altug; Isiksacan, Nilgun; Turen, Selahattin; Kokturk, Ugur; Yilmaz, Emre; Karakayalı, Muammer; Tosu, Aydin Rodi
Dergi: Dicle Tıp Dergisi, Vol. 45 No. 4, 2018
Anahtar kelimeler: Vitamin D; Mortality; SYNTAX score.

Objective:Vitamin-D status is very important for optimal function of human bodyespecially cardiovascular system. The aim of this study was to investigate thelong term prognostic value of admission vitamin D level in acute ST-segmentelevation myocardial infarction (STEMI) undergoing primary percutaneous coronaryintervention (PPCI). Methods:One hundred fifty seven consecutive patients, who were admitted to a trainingand research hospital with a diagnosis of STEMI and underwent PPCI, wererecruited in this prospective study. The study patients were divided into 2groups according to their vitamin-D levels as follows: High vitamin-D group(n=80) and Low vitamin-D group (n=77). The severity of coronary artery disease(CAD) was assessed with calculation of the SYNTAX score. Results:There were significant negative correlations between Vitamin-D level and SYNTAXscore, serum glucose, and gender, but a positive correlation with hemoglobinlevel. Cardiovascular mortality was found to be significantly higher in the lowvitamin-D group as compared to the high group (p<0.001). In multivariateanalysis, low vitamin-D level was found as a significant independent predictorof long term cardiovascular mortality after adjusting for other risk factors. Conclusion:We demonstrated that low admission vitamin-D is related to severity of CAD.Vitamin-D deficiency is an independent predictor for long term cardiovascularmortality in acute STEMI undergoing PPCI.

Objective:Vitamin-D status is very important for optimal function of human bodyespecially cardiovascular system. The aim of this study was to investigate thelong term prognostic value of admission vitamin D level in acute ST-segmentelevation myocardial infarction (STEMI) undergoing primary percutaneous coronaryintervention (PPCI). Methods:One hundred fifty seven consecutive patients, who were admitted to a trainingand research hospital with a diagnosis of STEMI and underwent PPCI, wererecruited in this prospective study. The study patients were divided into 2groups according to their vitamin-D levels as follows: High vitamin-D group(n=80) and Low vitamin-D group (n=77). The severity of coronary artery disease(CAD) was assessed with calculation of the SYNTAX score. Results:There were significant negative correlations between Vitamin-D level and SYNTAXscore, serum glucose, and gender, but a positive correlation with hemoglobinlevel. Cardiovascular mortality was found to be significantly higher in the lowvitamin-D group as compared to the high group (p<0.001). In multivariateanalysis, low vitamin-D level was found as a significant independent predictorof long term cardiovascular mortality after adjusting for other risk factors. Conclusion:We demonstrated that low admission vitamin-D is related to severity of CAD.Vitamin-D deficiency is an independent predictor for long term cardiovascularmortality in acute STEMI undergoing PPCI.