Endoskopik incelemede saptanan mide poliplerinin yerleşimi, histopatolojik  tipleri ve Heli kobakter pilori infeksiyonu ile ilişkisi
Location of endoscopic examination-detected gastric polyps, histopathological types and association  with Helicobacter pylori infection
Yazar: Soytürk, Müjde; Özdinç, Seda Akkaya; Sarıoğlu, Sülen; Sağol, Özgül; Hakim, Gözde Derviş; Topalak, Ömer
Dergi: Endoskopi Gastrointestinal, Vol. 20 No. 1, 2015
Anahtar kelimeler: Gastric polyp, endoscopy, Helicobacter pylori, hyperplastic, fundic ; Mide, polip, Helikobakter pilori, hiperplastik, fundik

Amaç: Gastrik polipler genellikle asemptomatiktir ve endoskopik girişimler  sırasında yaklaşık %2-6 oranında rastlanmaktadır. Midede en sık fundik  gland polipleri ile hiperplastik polipler görülmektedir. Çalışmanın amacı DEÜTF Gastroenteroloji kliniğinde yapılan üst gastrointestinal sistem endoskopileri sırasında saptanmış mide poliplerinin yerleşim yerini, histopatolojik  tiplerini ve Helikobakter pilori infeksiyonu ile olan ilişkilerini araştırmaktır.  Gereç ve Yöntem: Ocak 2010 - Haziran 2011 tarihleri arasında DEÜTF Gastroenteroloji Kliniği'nde yapılan endoskopik incelemeler sırasında mide polibi saptanmış olan 80 hasta (63 K, 17 E, Ort. Yaş: 60.12±12.76) ve bu hastalardan çıkarılmış olan toplam 174 polibe ait veriler retrospektif olarak gözden  geçirilmiştir. Bulgular: Mide polipleri 51 olguda (%64) korpus, 19 olguda  (%24) fundus, 16 olguda (%20) antrumda yerleşmiştir. Histolojik olarak; 38  olguda (%47,5) hiperplastik polip, 16 olguda (%20) fundik gland polibi, 7  olguda (%8,8) nöroendokrin tümör, 2 olguda (%2,5) adenomatöz polip, 1 olguda (%1,3) hamartamatöz polip, 1 olguda (%1,3) inflamatuar fibroid polip  ve 17 olguda (%21,3) faveolar hiperplazi saptanırken 1 olguda (%1,3) polip  spesifiye edilememiştir. Hiperplastik polipler genellikle tek bulunma eğiliminde iken fundik polipler multipl olma eğilimindeydi. Tartışma: Midede en  sık görülen polipler hipeplastik poliplerdir. Hiperplastik poliplerin Helikobakter pilori enfeksiyonu ile midedeki gastrit ve intestinal metaplazi ile ilişkisi mevcuttur. Midede nöroendokrin tümör sıklığı artmaktadır.

Background/aims: Gastric polyps are usually asymptomatic and found in approximately 2-6% of upper gastrointestinal endoscopic procedures. Hyperplastic  polyps and fundic gland polyps are the two most common subtypes of gastric  polypoid lesions. The aim of this study was to determine the characteristics of patients with gastric polyps diagnosed through endoscopy, the histological characteristics and location of the polyps and the presence or not of Helicobacter pylori infection. Materials and Methods: Dyspeptic patients with gastric polypoid lesions  detected by upper gastrointestinal endoscopy at Dokuz Eylül University Gastroenterology Clinic between January 2010 and June 2012 were analyzed retrospectively. Data including the patients' age and sex, the number, location and histopathologic type of polyps and the presence of Helicobacter pylori infection were recorded. Eighty patients with gastric polypoid lesion (63 F, 17 M, mean age:  60.1±12.8 years) were enrolled in the study. One-hundred and seventy-four gastric polypoid lesions were identified in 80 patients. Results: Polypoid lesions were commonly located in the corpus (64%), followed by fundus (24%) and antrum  (20%). The most frequently encountered histopathologic subtype of gastric polypoid lesions was hyperplastic polyp (48%), followed by foveolar hyperplasia  (21%), fundic gland polyps (20%), neuroendocrine tumor (9%), adenoma (1%),  hamartomatous (1%) and inflammatory fibroid polyp (1%). Hyperplastic polyps  were primarily single, whereas fundic gland polyps tended to be multiple. Hyperplastic polyps were associated with Helicobacter pylori infection, chronic active gastritis and intestinal metaplasia. Conclusions: The most frequently encountered  histopathologic subtype of gastric polypoid lesions was hyperplastic polyp. The  prevalence of neuroendocrine tumors seems to be higher than that reported earlier, most likely because of the widespread use of proton pump inhibitors.