Association with Platelet Distribution Width and New-Onset   Atrial Fibrillation After Coronary Artery Bypass Grafting
Association with Platelet Distribution Width and New-Onset   Atrial Fibrillation After Coronary Artery Bypass Grafting
Yazar: Özyurtlu, Ferhat; Albayrak, Gökhan
Dergi: Dicle Tıp Dergisi, Vol. 45 No. 3, 2018
Anahtar kelimeler: Atrial fibrillation,coronary artery bypass surgery,platelet distribution width,white blood cell

Objective:The platelet distribution width (PDW) is one of the parameters of plateletactivation. The PDW directly measures the variability in platelet size. However,there has been a limited number of data reported thus far on PDW andpostoperative AF in patients undergoing CABG. We aimed to investigate therelationship between the PDW and postoperative AF in patients undergoing CABG. Methods:124 consecutive patients with sinus rhythm who had undergone CABG between July2011 and December 2013 were evaluated. AF was defined as any episode of AFlasting longer than 30 seconds. Complete blood count samples were analyzedaccording to the results obtained within 48 hours of the preoperative andpostoperative period.  Results:The preoperative PDW levels were significantly lower in patients who haddeveloped AF than in the control group (56.5±14.8 vs. 50.9±10.0, p=0.015).There was no correlation between the postoperative PDW levels and AF. Thepreoperative white blood cell (WBC) and the neutrophil/lymphocyte ratio (NLR)were found to be similar between the two groups, while the postoperative WBC(13.9±5.7 vs. 10.5±3.6, p=0.000) and NLR (14.4±9.4 vs. 9.0±8.4, p: 0. 001)levels were higher in the group of patients who had AF. An NLR of 8.5 predictedpost-CABG AF with a sensitivity of 73% and a specificity of 63%, and a WBC of10 predicted post-CABG AF with a sensitivity of 77% and a specificity of 48%.  Conclusion:These results support the hypothesis that preoperative PDW level predictsnew-onset AF after CABG, but suggest that other factors are also important.

Objective:The platelet distribution width (PDW) is one of the parameters of plateletactivation. The PDW directly measures the variability in platelet size. However,there has been a limited number of data reported thus far on PDW andpostoperative AF in patients undergoing CABG. We aimed to investigate therelationship between the PDW and postoperative AF in patients undergoing CABG. Methods:124 consecutive patients with sinus rhythm who had undergone CABG between July2011 and December 2013 were evaluated. AF was defined as any episode of AFlasting longer than 30 seconds. Complete blood count samples were analyzedaccording to the results obtained within 48 hours of the preoperative andpostoperative period.  Results:The preoperative PDW levels were significantly lower in patients who haddeveloped AF than in the control group (56.5±14.8 vs. 50.9±10.0, p=0.015).There was no correlation between the postoperative PDW levels and AF. Thepreoperative white blood cell (WBC) and the neutrophil/lymphocyte ratio (NLR)were found to be similar between the two groups, while the postoperative WBC(13.9±5.7 vs. 10.5±3.6, p=0.000) and NLR (14.4±9.4 vs. 9.0±8.4, p: 0. 001)levels were higher in the group of patients who had AF. An NLR of 8.5 predictedpost-CABG AF with a sensitivity of 73% and a specificity of 63%, and a WBC of10 predicted post-CABG AF with a sensitivity of 77% and a specificity of 48%.  Conclusion:These results support the hypothesis that preoperative PDW level predictsnew-onset AF after CABG, but suggest that other factors are also important.