THE ROLE OF PET CT IN CANCER OF UNKNOWN PRIMARY Primeri Bilinmeyen Kanserlerde PET BT'nin Rolü
THE ROLE OF PET CT IN CANCER OF UNKNOWN PRIMARY Primeri Bilinmeyen Kanserlerde PET BT'nin Rolü
Yazar: Kandemır, Ozan; Kandemir, Fadime
Dergi: Bozok Tıp Dergisi, Vol. 13 No. 2, 2023
Anahtar kelimeler: Nuclear Medicine ; Nükleer Tıp ; THE ROLE OF PET CT IN CANCER OF UNKNOWN,PRIMARY,Primeri Bilinmeyen Kanserlerde PET BT

ABSTRACTObjective: This study aimed to investigate the diagnostic value of positron emission tomography/computedtomography (PET/CT) in detecting the primary focus and in suspicious foci in patients who underwent PET/CT with a pre-diagnosis of carcinoma of unknown primary.Material and Methods: In this retrospective study, a total of 49 patients who underwent PET/CT scan witha prediagnosis of carcinoma of the unknown primary between 2015 and 2019, and whose clinical follow-upand histopathological data were available, were included. PET/CT study was performed in 20 (40%) patientsafter the metastatic lesion was detected as a result of pathology, and in 29 (60%) patients due to clinicalfindings and imaging methods and suspicion of malignancy. The histopathological and clinical evaluation ofthe patients before PET/CT and the primary surgery, histopathological examinations and clinical follow-upsafter PET/CT were examined. The success of PET/CT in detecting primary lesions and evaluating suspiciouslesions in metastatic cases was analyzed.Results: Seventeen (34.7%) of the patients were female and 32 (65.3%) were male. A primary malignanttumor was detected in 34 (85%) of 40 patients with PET/CT. Regional distribution in patients with primarycancer focus; 9 pancreases, 9 lungs, 4 livers, 3 urothelial, 2 thyroids, 1 vertebra, 1 breast, 1 ovary, 1 esophagus,1 prostate, 1 iliac bone, 1 skin, 1 stomach and 1 colon. In the follow-up of 6 cases whose primary couldnot be determined; Cervical cancer was detected in 1, ovarian cancer in 1, and the primary focus could notbe detected in the clinical follow-up of 4 metastatic patients.Conclusion: PET/CT is highly successful in detecting cancers whose primary is unknown. Therefore, PET/CT isa diagnostic imaging method for the detection of the primary in cancer patients whose primary is unknown.

ABSTRACTObjective: This study aimed to investigate the diagnostic value of positron emission tomography/computedtomography (PET/CT) in detecting the primary focus and in suspicious foci in patients who underwent PET/CT with a pre-diagnosis of carcinoma of unknown primary.Material and Methods: In this retrospective study, a total of 49 patients who underwent PET/CT scan witha prediagnosis of carcinoma of the unknown primary between 2015 and 2019, and whose clinical follow-upand histopathological data were available, were included. PET/CT study was performed in 20 (40%) patientsafter the metastatic lesion was detected as a result of pathology, and in 29 (60%) patients due to clinicalfindings and imaging methods and suspicion of malignancy. The histopathological and clinical evaluation ofthe patients before PET/CT and the primary surgery, histopathological examinations and clinical follow-upsafter PET/CT were examined. The success of PET/CT in detecting primary lesions and evaluating suspiciouslesions in metastatic cases was analyzed.Results: Seventeen (34.7%) of the patients were female and 32 (65.3%) were male. A primary malignanttumor was detected in 34 (85%) of 40 patients with PET/CT. Regional distribution in patients with primarycancer focus; 9 pancreases, 9 lungs, 4 livers, 3 urothelial, 2 thyroids, 1 vertebra, 1 breast, 1 ovary, 1 esophagus,1 prostate, 1 iliac bone, 1 skin, 1 stomach and 1 colon. In the follow-up of 6 cases whose primary couldnot be determined; Cervical cancer was detected in 1, ovarian cancer in 1, and the primary focus could notbe detected in the clinical follow-up of 4 metastatic patients.Conclusion: PET/CT is highly successful in detecting cancers whose primary is unknown. Therefore, PET/CT isa diagnostic imaging method for the detection of the primary in cancer patients whose primary is unknown.