Evaluation of Patient Follow-up with Transient Hypogammaglobulinemia in Infancy Diagnosis
Evaluation of Patient Follow-up with Transient Hypogammaglobulinemia in Infancy Diagnosis
Yazar: Yorulmaz, Alaaddin; Artaç, Hasibe; Reisli, İsmail
Dergi: Çağdaş Tıp Dergisi, Vol. 9 No. 1, 2019
Anahtar kelimeler: Health Care Administration ; Sağlık Kurumları Yönetimi ; Transient hypogammaglobunemia,immunodeficiency

Introduction: In this study, we aimed to investigate the clinical, laboratory anddemographic characteristics of patients with THI who were admitted with thesuspicion of recurrent infection and immunodeficiency.Methods: The study included 287 patients whowere followed up with the diagnosis of transient hypogammaglobulinemia ininfancy at Selçuk University Meram Faculty of Medicine, Child Health andDiseases Department and Department of Pediatric Allergy and Immunology, betweenNovember 2001 and November 2006. The age, gender, the age of the complaints anddiagnosis, clinical features, family history and laboratory findings of thepatients were examined. The data of the patients were collected by using thehospital file and the records in the Pediatric Immunology cards.Results: 195 (67.9%) of the patients were male and 92 (32.1%) werefemale (p <0.05). The M/F ratio was 2.1. The age of diagnosis ranged from 8months to 48 months with a mean of 24.6±11.3 months. The duration between thecomplaints and the age of diagnosis was between 1 and 63 months and the meanage was 13.5±8.6 months. Complaints of the patients were recurrent upperrespiratory tract infection (URTI) 54.35% (n:156), lower respiratory tractinfection (LRTI) 50.52% (n:145), sinusitis 41.26% (n:118), recurrent otitis,28.22% (n:81), asthma finding 12.89% (n=37), allergic skin and rhinitisfindings 10.45% (n:30), gastroenteritis 6.96% (n:20), urinary tract infection4.18% (n:12), and moniliazis was 3.83% (n:11). Conclusion: THI is usually a self-recovering disease around three yearsof age. In order to prevent complications such as chronic lung disease and toreduce morbidity, it is important to follow up the cases regularly.

Introduction: In this study, we aimed to investigate the clinical, laboratory anddemographic characteristics of patients with THI who were admitted with thesuspicion of recurrent infection and immunodeficiency.Methods: The study included 287 patients whowere followed up with the diagnosis of transient hypogammaglobulinemia ininfancy at Selçuk University Meram Faculty of Medicine, Child Health andDiseases Department and Department of Pediatric Allergy and Immunology, betweenNovember 2001 and November 2006. The age, gender, the age of the complaints anddiagnosis, clinical features, family history and laboratory findings of thepatients were examined. The data of the patients were collected by using thehospital file and the records in the Pediatric Immunology cards.Results: 195 (67.9%) of the patients were male and 92 (32.1%) werefemale (p <0.05). The M/F ratio was 2.1. The age of diagnosis ranged from 8months to 48 months with a mean of 24.6±11.3 months. The duration between thecomplaints and the age of diagnosis was between 1 and 63 months and the meanage was 13.5±8.6 months. Complaints of the patients were recurrent upperrespiratory tract infection (URTI) 54.35% (n:156), lower respiratory tractinfection (LRTI) 50.52% (n:145), sinusitis 41.26% (n:118), recurrent otitis,28.22% (n:81), asthma finding 12.89% (n=37), allergic skin and rhinitisfindings 10.45% (n:30), gastroenteritis 6.96% (n:20), urinary tract infection4.18% (n:12), and moniliazis was 3.83% (n:11). Conclusion: THI is usually a self-recovering disease around three yearsof age. In order to prevent complications such as chronic lung disease and toreduce morbidity, it is important to follow up the cases regularly.