Bilinen ve Olası Risk Faktörlerinin Birlikteliğinin Gestasyonel Diyabetes Mellitus Gelişimine Etkisi
The Effect of Common and Possible Risk Factors’ Co-occurrence to the Development of Gestational Diabetes Mellitus
Yazar: Gürkan, Eren; Dirican, Emre; Bülbül, Neşe
Dergi: Ankara Medical Journal, Vol. 18 No. 3, 2018
Anahtar kelimeler: Health Care Administration ; Sağlık Kurumları Yönetimi ; Gestational diabetes mellitus,multiple pregnancies,maternal age,obesity ; Gestasyonel diyabetes mellitus,artan gebelik sayısı,maternal yaş,obesite,,

Objectives: Advanced maternal age,obesity, presence of family history of diabetes and macrosomic infant deliveryare common risk factors for gestational diabetes (GDM). The increase inpregnancy weight and number of pregnancies are also possible risk factors. Thepurpose of this study was to assess the association of common and possible riskfactors with GDM development.Materials and Methods: Acase-control study was planned with a structured questionnaire on GDMscreening. For this purpose, pregnant patients who applied to the Hatay StateHospital gynecology and obstetric outpatient clinic between January and October2017 were included in the study. 181 case records who were applied a two-steporal glucose tolerance test (OGTT) were scanned. 102 participants were includedin this study. In our study, the data were analyzed statistically using 95%confidence, using the SPSS 22 (Statistical Package for the Social Sciences)package program. The significance level of all the tests used was determined tobe 0.05. Pearson-Continuity Correction-Fisher Exact Chi-Square tests, binarylogistic regression (enter method) analyzes were used in the study.Results: 74 of our 102 participants(72.50%) were non-GDM and 28 (27.50%) were GDM. The average age is 29.04 ±6.11. Univariate relations with GDM are investigated, age (p=0.001), prevalenceof GDM at previous pregnancies (p=0.002), presence of diabetes mellitus familyhistory (p=0.001), increase of body weight in pregnancy (p=0.011), presence ofglycosuria before pregnancy (p= 0.020), multiple pregnancies (p=0.012),presence of macrosomic baby delivery (p=0.027). However, when the significanceof risk factors is evaluated together with logistic regression analysis,advancing maternal age, multiple pregnancies and presence of diabetes mellitusfamily history increases the risk of GDM. Body mass index (BMI) and the weightof the first two trimester weight> 8 kg are not significant.Conclusion: Presence of diabetesmellitus family history, increased maternal age together with BMI, multiplepregnancies increases GDM risk. These risk factors need to be considered inprenatal screening.

Objectives: Advanced maternal age, obesity,presence of family history of diabetes and macrosomic infant delivery are knownrisk factors for gestational diabetes (GDM). The increase in pregnancy weightand number of pregnancies are also possible risk factors. The purpose of thisstudy was to assess the association of known and possible risk factors with GDMdevelopment.Materials and Methods: Acase-control study was planned with a structured questionnaire on gestationaldiabetes mellitus screening. For this purpose, pregnant patients who applied tothe Hatay State Hospital gynecology and obstetric outpatient clinic betweenJanuary and October 2017 were included in the study. 181 case records who wereapplied a two-step oral glucose tolerance test (OGTT) were scanned. 102participants were included in this study. In our study, the data were analyzedstatistically using 95% confidence, using the SPSS 22 (Statistical Package forthe Social Sciences) package program. The significance level of all the testsused was determined to be 0,05. Pearson-ContinuityCorrection-FisherExactChi-Squaretests, binary logistic regression (enter method) analyzes were used in thestudy.Results: 74 of our 102 participants(72.50%) were non-GDM and 28 (27.50%) were GDM. The average age is 29,04 ±6.11. Univariate relations with GDM are investigated, age (p=0,001), prevalenceof GDM at previous pregnancies (p=0,002), presence of diabetes mellitus familyhistory (p=0,001), increase of body weight in pregnancy (p=0,011), presence ofglycosuria before pregnancy (p= 0,020), multiple pregnancies (p=0,012),presence of macrosomic baby delivery (p=0,027). However, when the significanceof risk factors is evaluated together with logistic regression analysis,advancing maternal age, multiple pregnancies and presence of diabetes mellitusfamily history increases the risk of GDM. Body mass index (BMI) and the weightof the first two trimester weight> 8 kg are not significant.Conclusion: Presence of diabetesmellitus family history, increased maternal age together with BMI, multiplepregnancies increases GDM risk. These risk factors need to be considered inprenatal screening.