Preoperatif MPV; KABGO sonrası Serebrovasküler Olay için prediktör olabilir mi?
Preoperatif MPV; KABGO sonrası Serebrovasküler Olay için prediktör olabilir mi?
Yazar: Aygün, Fatih; Özülkü, Mehmet; Günday, Murat
Dergi: Cumhuriyet Tıp Dergisi, Vol. 36 No. 4, 2014
Anahtar kelimeler: CABG, mean platalet volume, stroke ; KABGO, ortalama trombosit hacmi (mpv), inme

ÖzetAmaç. Çalışmamızda; izole Koroner Arter Bypas Greft Operasyonu (KABGO) uygulanmış hastalarda, preoperatif MPV değerleri ile postoperatif serebrovasküler olay (SVO) arasındaki ilişki araştırıldı. Yöntem. Ocak 2010 ve Haziran 2014 arasında Kalp ve Damar Cerrahisi Kliniği’nde KABGO yapılmış 265 hasta çalışmaya alınmıştır. Homojen bir çalışma grubu oluşturmak için; diyaliz giren, kreatinin seviyeleri 2 mg/dL’nin üstünde olan, operasyon içerisinde aortada makroskopik patoloji tespit edilen ve bu sebeple operasyon prosedüründe değişiklik yapılan hastalar ile acil statüsünde ve re-do operasyona alınan hastalar çalışmaya dahil edilmemiştir. Çalışmadaki bütün hastalara izole KABGO (kros klemp kullanılarak on-pump veya pompa destekli beating heart veya beating heart) yapılmıştır. Hastaların hepsinde kros klemp süreleri 70 dakikayı, kardiyopulmoner bypass süreleri 120 dakikayı geçmemiştir. Preoperatif dönemde çalışmaya katılan hastaların kan örnekleri, antikoagülan olarak etilen diamin tetra asetik asit (EDTA) bulunan standart tüplere alınmıştır. Toplanan bu örneklere, Sysmex KX-21N cihazı kullanılarak analiz yapılmış ve MPV değerleri elde edilmiştir. Bulgular. Çalışmaya katılan hastaların preoperatif MVP değerleri; Grup 1’de 7,04 ± 0,5 Femtolitre (fL) (mean ± standart sapma) iken, Grup 2’de 9,05 ± 1,3 fL olduğu tespit edildi. Sonuç. Yapılan istatiksel analizde, preoperatif yüksek MPV değerleri ile postoperatif SVO arasında anlamlı ilişki olduğu tespit edilmiştir (p<0,05; p=0,028).Anahtar sözcükler: KABGO, ortalama trombosit hacmi (mpv), inme AbstractAim. In our study; we researched relation between preoperative MPV values and postoperative SVO in patients who underwent isolated CABG surgery. Metohds. 265 patients who underwent isolated CABG surgery in depertmant of Cardiovascular Surgery between January 2010 and June 2014, were taken in this study. Because of homogeneous study group was constituted, this study do not include patients who patients with dialysis, patients have creatinin level>2 mgr/dL, patients who plaque were showed on aortic wall in this causes changes operation style, patiens underwent emergency surgery. All patients in our study were performed CABG (on-pump with cross clamp or pump support beating heart or beating heart) surgery. All patients cross clamp and cardiopulmonary bypass times less than 70 min. and 120 min. In preoperative period, blood samples of all participants were taken with standart tubes including EDTA. Collected these samples were analysed with Sysmex KX-21N system and MPV values were determined. Results. Preoperative MPV values of patients who to be added in our study, in the group 1 was found mean ± standart deviation 7.04 ± 0.5 Femtoliter (fL) while, in the group 2 was found mean ± standart deviation 9.05 ± 1.3 fL. Conclusion. According to was made statistically analysis, it was found significant relation between preoperative high MPV values and postoperative SVO (p<0.05, p=0.028).Keywords: CABG, mean platalet volume, stroke

Aim. In our study; we researched relation between preoperative MPV values and postoperative SVO in patients who underwent isolated CABG surgery. Metohds. 265 patients who underwent isolated CABG surgery in depertmant of Cardiovascular Surgery between January 2010 and June 2014, were taken in this study. Because of homogeneous study group was constituted, this study do not include patients who patients with dialysis, patients have creatinin level>2 mgr/dL, patients who plaque were showed on aortic wall in this causes changes operation style, patiens underwent emergency surgery. All patients in our study were performed CABG (on-pump with cross clamp or pump support beating heart or beating heart) surgery. All patients cross clamp and cardiopulmonary bypass times less than 70 min. and 120 min. In preoperative period, blood samples of all participants were taken with standart tubes including EDTA. Collected these samples were analysed with Sysmex KX-21N system and MPV values were determined. Results. Preoperative MPV values of patients who to be added in our study, in the group 1 was found mean ± standart deviation 7.04 ± 0.5 Femtoliter (fL) while, in the group 2 was found mean ± standart deviation 9.05 ± 1.3 fL. Conclusion. According to was made statistically analysis, it was found significant relation between preoperative high MPV values and postoperative SVO (p