P-aminobenzoik asit türevlerinin komplekslerinin sentezi ve özellikleri
Synthesis and properties of complexes of derivatives of p-aminobenzoic acid
Yazar: ÖZGÜR AYBİRDİ
Danışman: PROF. DR. HACALİ NECEFOĞLU
Kafkas Üniversitesi / Fen Bilimleri Enstitüsü / Kimya Ana Bilim Dalı
Derece: Doktora, 2010
Konu: Kimya = Chemistry
Dizin: Kompleks yapılar = Complex structures ; Koordinasyon bileşikleri = Coordination compounds ; Kristal yapı = Crystal structure

Özet:
Bu çalışmada Cu(II), Co(II), Ni(II), Mn(II), Zn(II) ve Cd(II) metallerinin p-aminobenzoik asit türevi olan p-metilaminobenzoik asit (MABA), p-dimetilaminobenzoik asit (DMABA), p-dietilaminobenzoik asit (DEABA) ve biyolojik öneme sahip nikotinamid (NA) ve türevleri (dietilnikotinamid (DENA) ve izonikotinamid (İNA)) ile 28 adet yeni karışık ligand kompleksleri sentezlendi:[Cu2(DMAB)4(İNA)2] (1), [Co(DMAB)2(İNA)(H2O)2] (2), [Ni(DMAB)2(İNA)(H2O)2] (3), [Zn(DMAB)2(İNA)(H2O)2] (4), [Mn(DMAB)2(İNA)(H2O)2] (5), [Cd(DMAB)2(İNA)(H2O)2] (6), [Ni(DMAB)2(DENA)2(H2O)2] (7), [Co(DMAB)2(DENA)2(H2O)2] (8), [Zn2(DMAB)4(DENA)2] (9), [Cu2(DEAB)4(H2O)2] (10), [Ni(DEAB)2(H2O)3].2H2O (11), [Co(DEAB)2(H2O)3].2H2O (12), [Mn(DEAB)2(H2O)3].2H2O (13), [Zn2(DEAB)4] (14), [Zn2(DEAB)4(DENA)2] (15), [Co2(DEAB)4(DENA)2] (16), [Ni(DEAB)2(DENA).H2O] (17), [Co(DEAB)2(NA)2] (18), [Ni(DEAB)2(NA)2] (19), [Zn2(MAB)4(DENA)2].2H2O (20), [Ni(MAB)2(NA)2(H2O)2] (21), [Zn(MAB)2(NA)2] (22), [Cu(MAB)2(NA)2.H2O] (23), [Co(MAB)2(NA)2(H2O)2].2H2O (24), [Zn(MAB)2(İNA)2].H2O (25), [Co(MAB)2(İNA)(H2O)2] (26), [Zn2(MAB)4(H2O)2] (27), [Cu2(MAB)4(H2O)2] (28)Komplekslerin yapıları elementel analiz, kütle spektrometrisi, IR, UV, 1H-NMR, 13C-NMR ve ESR spektroskopi verileri ile karakterize edilmiştir. X-Ray analizi ile on iki adet kompleksin kristal ve moleküler yapısı aydınlatılmıştır. Neticede 1, 9, 10, 20, 27 ve 28 nolu komplekslerin kare piramidal, 14, 16 ve 22 nolu komplekslerin tetrahedral, diğer komplekslerin ise oktahedral geometriye sahip oldukları belirlendi.

Abstract:
In this study, the 28 new mixed complexes of Cu(II), Co(II), Ni(II), Mn(II), Zn(II) and Cd(II) with p-methylaminobenzoic acid (MABA), p-dimethylaminobenzoic acid (DMABA), p-diethylaminobenzoic acid (DEABA) which are derivatives of p-aminobenzoic acid, and with biologically active nicotinamide and derivatives of nicotinamide (diethylnicotinamide (DENA) and isonicotinamide (INA)) have been synthesized:[Cu2(DMAB)4(INA)2] (1), [Co(DMAB)2(INA)(H2O)2] (2), [Ni(DMAB)2(INA)(H2O)2] (3), [Zn(DMAB)2(INA)(H2O)2] (4), [Mn(DMAB)2(INA)(H2O)2] (5), [Cd(DMAB)2(INA)(H2O)2] (6), [Ni(DMAB)2(DENA)2(H2O)2] (7), [Co(DMAB)2(DENA)2(H2O)2] (8), [Zn2(DMAB)4(DENA)2] (9), [Cu2(DEAB)4(H2O)2] (10), [Ni(DEAB)2(H2O)3].2H2O (11), [Co(DEAB)2(H2O)3].2H2O (12), [Mn(DEAB)2(H2O)3].2H2O (13), [Zn2(DEAB)4] (14), [Zn2(DEAB)4(DENA)2] (15), [Co2(DEAB)4(DENA)2] (16), [Ni(DEAB)2(DENA).H2O] (17), [Co(DEAB)2(NA)2] (18), [Ni(DEAB)2(NA)2] (19), [Zn2(MAB)4(DENA)2].2H2O (20), [Ni(MAB)2(NA)2(H2O)2] (21), [Zn(MAB)2(NA)2] (22), [Cu(MAB)2(NA)2.H2O] (23), [Co(MAB)2(NA)2(H2O)2].2H2O (24), [Zn(MAB)2(INA)2].H2O (25), [Co(MAB)2(INA)(H2O)2] (26), [Zn2(MAB)4(H2O)2] (27), [Cu2(MAB)4(H2O)2] (28)The complexes were characterized by elemental analysis, mass spectrometry, IR, 1H-NMR, 13C-NMR, UV-vis, ESR spectroscopy, thermogravimetry measurements. Crystal and molecular structures of twelve compexes were determined by X-ray analysis. Concequently, it has been determined that complexes 1, 9, 10, 20, 27 and 28 have square-pyramidal, complexes 14, 16 and 22 have tetrahedral, and the others complexes have octahedral geometries.