Van yöresi sanayi sitesinde çalışan işçilerin kan serumlarında bazı elementler (çinko, krom, kurşun ve kadmiyum) ile bazı karaciğer enzimleri (ast, alt) seviyesinin tayini
Examining the level of some levels (zinc, chromium, lead and cadmium) and some liver enzymes (ast, alt) within the blood-serum of the car-reparing shops in the vicinity of Van
Yazar: MUSTAFA BİLİCİ
Danışman: YRD. DOÇ. DR. NURHAYAT ATASOY
Yüzüncü Yıl Üniversitesi / Fen Bilimleri Enstitüsü / Kimya Ana Bilim Dalı
Derece: Yüksek Lisans, 2005
Konu: Kimya = Chemistry

Özet:
Bu çalışmada, sanayi sitesinde çalışan işçilerin kan serumlarında bazı elementler (çinko, krom, kurşun ve kadmiyum) ile bazı karaciğer enzimlerinin (AST, ALT) seviyesi araştırıldı. Araştırma materyali Van yöresi sanayi sitesinde çalışan işçiler ile sanayi bölgesi dışında yaşayan kişilerden alınan kan serumlarından oluşturuldu. Araştırma kişisel alışkanlıklar dikkate alınarak yürütülmüştür. Hasta ve kontrol grubunda alınan kan örneklerinde kurşun, kadmiyum, çinko, krom ve enzim aktiviteleri ölçülerek elde edilen sonuçlar student T-testine göre analizler yorumlandı. Elde edilen sonuçlara göre sanayi sitesinde çalışan işçilerde AST miktarı 27.3055± 9.50 U/L kontrol grubundaki AST miktarı 19.56+ 4.97 U/L olarak bulundu. Sanayi sitesinde çalışan işçilerde ALT miktarı 35.00+ 12.62 U/L kontrol grubundaki ALT miktarı 18.72+4.70 U/L ve p<0.001 istatiksel olarak önemli bulundu. Pb miktarı sanayi işçilerinde 0.0630+0.051 ug/100mL kontrol grubunda 0.024+ 0.017 ug/lOOml ve p<0,05 derecesinde önemli, Cd miktarı sanayi işçilerinde 0.0058+ 0.0029 ug/100mL kontrol grubunda 0.0028+ 0.002 ug/100ml ve p<0,05 derecesinde önemli, Zn miktarı sanayi işçilerinde 0.3800+ 0.085 |ig/100mL kontrol grubunda 0.3400+0.062 ug/lOOml olarak bulundu. Cr miktarı sanayi işçilerinde 0.077+0.011 ug/100mL kontrol grubunda 0.047+0.019 ug/100ml olarak saptandı. Anahtar kelimeler Enzim (AST, ALT), Kurşun, Kadmiyum, Çinko, Krom, Kan, Serum

Abstract:
In this study, it is aimed to examine the level of some elements (zinc, chromium, lead, and cadmium), and some liver enzymes (AST, ALT) within the blood-serum of the workers at the car-repairing shops in the vicinity of Van. Examining material was made from the blood taken from the workers at the car- repairing shops, and from those who live out of that cite. Personal habits were taken into consideration while this investigation was fulfilled. The sample blood was taken Brom the patient and the control group, and was examined for the level of zinc, chromium, lead, and cadmium, and for some liver enzymes such as; AST, and ALT. And the results were evaluated according to the "Student T-test ". It was found that for the workers at the car-repairing shops, the quantity of AST was 27.3055+ 9.50 U/L and for the control group it was 19.56+ 4.97 U/L. For the workers at the car- repairing shops the quantity of ALT was 35.00+ 12.62 U/L, and for the control group it was 18.72+ 4.70 U/L, and p<0.001 was found significant statistically. The level of Pb in the sample blood of workers was 0.0630+ 0.05 1 jig/lOOml, while in the blood of the control group it was 0.0240+ 0.017 jig/lOOmL and p<0,05 was an important difference. The Cd level within the sample blood of workers was 0.0058+ 0.002 (ig/lOOml, and in the blood of the control group it was 0.0028+ 0.002 ng/lOOml and it was significant at the degree of where p<0,05. The quantity of Zn was found 0.3800+ 0.085 ug/100ml for the workers, and for the control group it was 0.3400+0.062 ug/100ml. The Cr quantity was found 0.077+0.011 ng/lOOnu, and for the control group it was 0.047+0.019 ug/lOOml. Key words: Enzym (AST, ALT), Zinc, Chromium, Lead, Cadmium, Blood, Serum. Ul