Endometriozis ön tanılı 69 olgunun tedavi modalitelerinin karşılaştırılması
The comparison of treatment modalities in patients with prediagnosis of endometriosis
Yazar: ELİF AĞAÇAYAK
Danışman: YRD. DOÇ. DR. NURTEN AKDENİZ
Dicle Üniversitesi / Tıp Fakültesi / Kadın Hastalıkları ve Doğum Ana Bilim Dalı
Derece: Tıpta Uzmanlık, 2008
Konu: Kadın Hastalıkları ve Doğum = Obstetrics and Gynecology

Özet:
Çal mam z n amac Dicle Üniversitesi T p Fakültesi Kad n Hastal klar veDo um klini inde endometriozis tedavisinde uygulanan tedavi modalitelerininetkinlik, güvenirlilik aç s ndan kar la t r lmas d r.Çal mam zda endometriozis ön tan s yla tedaviye karar verilen 69hastan n 40 na laparoskopi, 16 s na laparotomi, 13 üne kombine tedavi(preoperatif medikal tedavi veya postoperatif medikal tedavi) uyguland .Her 3 gruptaki olgular n da l m nda ya , medeni durumu, meslek, sigarakullan p kullanmad , ikayetleri, fertilite durumu, infertil hastalar n tedavisonras gebelik durumu, gebelik olu anlar n hangi yöntemle gebe kald , tedaviöncesi ve sonrastümör belirteçleri, tedavi öncesi ve sonrasUSG ik bulgularkaydedildi. 3 grup aras nda yada l m n n homojen olmadgörüldü vegruplar aras nda istatiksel olarak anlamlfarkl l k oldu u tespit edildi (p=0.002).Laparotomik cerrahi grubu daha ileri ya taki hastalara, laparoskopik cerrahidaha genç hastalara uygulanm t . Gruplar aras nda tümör belirteçleri tedaviöncesi ve sonraskar la t r ld . CA 15-3 düzeyinde 3.grupta istatiksel olarakanlamlfarkl l k izlendi (p=0.015). Gruplar aras nda medeni durum, meslek,sigara kullan p kullanmad , tedavi öncesi ve sonrasa rikayetinin durumu,tedavi öncesi infertilite ikayeti olanlar n gebelik durumu ve tedavi öncesi vesonrasUSG bulgulararas nda istatiksel olarak anlamlbir farkl l k izlenmedi.Tedavi sonrasgebelik olu anlar n gebelik meydana gelme yöntemi aç s ndan1.grup lehine istatiksel olarak anlaml farkl l k oldu u izlendi (p=0.036).

Abstract:
The aim of this study is to compare the efficiency and safety of thetreatment modalities of endometriosis administered in Obstetrics andGynecology department of Dicle University Faculty of Medicine Hospital.In our study, 40 of 69 patients whom were treated with the pre-diagnosisof endometriosis had laparoscopy, while 16 had laparotomy and 13 hadcombined treatment (preoperative medical treatment or postoperative medicaltreatment).Age, marital status, occupational status, cigarette smoking, complaints,fertility status, the presence of pregnancy of infertile patients after appropriatetreatment, the method used in those became pregnant, tumor marker levelsbefore and after treatment, and sonografical findings before and after treatmentwere registered in the distribution of all 3 patient groups. It was detected thatthe age distrubition among 3 groups was not homogeous and statisticallysignificant difference was seen among the groups (p=0.002). Laparotomicalsurgical intervention was performed to older patients and laparoscopicalsurgical intervention was performed to younger patients. Ca 15-3 levels of thethird group was found to be statistically significant when tumor marker levelsbefore/after treatment were compared among the groups (p=0.015). Nostatistical significance were shown in marital status, occupational status,cigarette smoking, pain complaints of before and after treatment; the presenceof pregnancy in those with infertility before treatment and subsequentsonografical findings among the groups. The method used in those whoconceived after treatment in the first group were established to be statisticallysignificant (p=0.036).