hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06382415, orgStudyIdInfo id: VINCat_PDO_2, briefTitle: Organ/Space Surgical Site Infection and Recurrence and Survival in Rectal Cancer Surgery, acronym: VINCat_PDO_2, statusModule overallStatus: COMPLETED, startDateStruct date: 2011-01-01, primaryCompletionDateStruct date: 2016-12-31, completionDateStruct date: 2024-03-31, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Hospital de Granollers, class: OTHER, descriptionModule briefSummary: In rectal cancer surgery, the organ/space surgical site infection (O/S-SSI) has an impact on patient's prognosis. Its influence in the oncologic outcomes remains controversial. The main objective is to assess the possible effect of O/S-SSI on long-term overall survival and cancer recurrence., conditionsModule conditions: Rectal Cancer, conditions: Organ-Space Surgical Site Infection, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 3826, type: ACTUAL, armsInterventionsModule, outcomesModule primaryOutcomes measure: Rate of overall cancer recurrence, primaryOutcomes measure: Overall survival, secondaryOutcomes measure: Rate of Organ-space surgical site infection, secondaryOutcomes measure: Rate of surgical complications, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hospital General de Granollers, city: Granollers, state: Barcelona, zip: 08402, country: Spain, geoPoint lat: 41.60797, lon: 2.28773, hasResults: False
protocolSection identificationModule nctId: NCT06382402, orgStudyIdInfo id: 23.0924, briefTitle: A CCTA Guided Management Strategy Versus a Standard of Care Strategy in Type 2 NSTEMI, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-30, primaryCompletionDateStruct date: 2026-04-30, completionDateStruct date: 2026-04-30, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-25, sponsorCollaboratorsModule leadSponsor name: University of Louisville, class: OTHER, descriptionModule briefSummary: This study design is a prospective randomized control trial to compare outcomes between the utilization of coronary computed tomography angiography (CCTA) vs conservative treatment in type 2 NSTEMI. The targeted population is expectedly heterogeneous and inpatient setting who are admitted and diagnosed with type 2 NSTEMI., conditionsModule conditions: Myocardial Injury, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 700, type: ESTIMATED, armsInterventionsModule interventions name: CCTA scan, outcomesModule primaryOutcomes measure: MACE, primaryOutcomes measure: Cardiovascular (CV) mortality, primaryOutcomes measure: Nonfatal MI, stroke, primaryOutcomes measure: Hospitalization for unstable angina, primaryOutcomes measure: Hospitalization for heart failure, primaryOutcomes measure: Unplanned revascularization, secondaryOutcomes measure: All-cause mortality, secondaryOutcomes measure: In-hospital and 90-day costs, secondaryOutcomes measure: Patient quality of life at 90 days, secondaryOutcomes measure: Diagnostic certainty scores, secondaryOutcomes measure: Individual components of the primary endpoint, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Louisville School of Medicine, Division of Cardiovascular Diseases, city: Louisville, state: Kentucky, zip: 40202, country: United States, contacts name: Dinesh Kalra, MD, role: CONTACT, phone: 502-588-7010, email: diniesh.kalra@louisville.edu, contacts name: Rongras Damrongwatanasuk, MD, role: CONTACT, phone: 502-588-7010, email: rongras.damrongwatanasuk@louisville.edu, geoPoint lat: 38.25424, lon: -85.75941, hasResults: False
protocolSection identificationModule nctId: NCT06382389, orgStudyIdInfo id: DR220204, secondaryIdInfos id: 2023-504691-18-00, type: CTIS, briefTitle: Efficacy of EMONO as an add-on Therapy to Conventional Antidepressants for the Treatment of Depressive Symptoms in Nursing-home Residents With Neurocognitive Disorders: a Randomized Controlled Trial-, acronym: PROTO-EHPAD, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06, primaryCompletionDateStruct date: 2026-08, completionDateStruct date: 2026-08, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: University Hospital, Tours, class: OTHER, descriptionModule briefSummary: Depression in neurocognitive disorders (Alzheimers' disease and related disoders) is a highly prevalent condition, especially in nursing homes. While it is associated with significant distress, the current conventional antidepressants have shown only modest efficacy and exposed to potentially severe side effects.Recent evidence suggests that nitrous oxide (N2O) in its most commonly used packaging of EMONO (Equimolar Mixture of Oxygen and Nitrous Oxide) has rapid antidepressant properties and a good safety profile. However, no study has investigating the antidepressant effect of EMONO in a population of depressed older adults with moderate to severe neurocognitive disorders in nursing homes.The principal goal of the PROTO-EHPAD study is to compare the changes in depressive symptoms in such individuals in a randomized controlled trial with a follow up period of 8 weeks, with a dosage escalation procedure., conditionsModule conditions: Depression, conditions: Neurocognitive Disorders, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Parallel assignement, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 96, type: ESTIMATED, armsInterventionsModule interventions name: EMONO, interventions name: Medical air, outcomesModule primaryOutcomes measure: Changes in the CORNELL depression severitý scale between S4 (one week after the last administration of MEOPA or medical air) and S1 (baseline)., secondaryOutcomes measure: CORNELL scale and GDS scale at weeks 1, 2, 3, 4 and 8, secondaryOutcomes measure: CGI-S and CGI-I scales at weeks 1, 2, 3, 4 and 8, secondaryOutcomes measure: The measurement of well-being by the EVIBE visual analogue scale at weeks 1, 2, 3, 4, and 8, secondaryOutcomes measure: Collection of adverse events at all study visits, eligibilityModule sex: ALL, minimumAge: 60 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06382376, orgStudyIdInfo id: 2024-60, briefTitle: The Effect of Analgesia Methods Applied in Gynecological Cancer Surgeries on Postoperative Analgesia, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-06-01, primaryCompletionDateStruct date: 2023-12-01, completionDateStruct date: 2024-03-01, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-26, sponsorCollaboratorsModule leadSponsor name: Bakirkoy Dr. Sadi Konuk Research and Training Hospital, class: OTHER_GOV, descriptionModule briefSummary: The aim of this study is to compare the effectiveness of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia in gynecological cancer surgeries.The key question(s) it aims to answer are:\[Is intrathecal morphine more effective in postoperative analgesia?\] Patients who underwent gynecological cancer surgery were examined retrospectively. The investigators evaluated the effect of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia on pain scores and postoperative opioid use., conditionsModule conditions: Gynecological Cancer Surgery, conditions: Regional Anesthesia Morbidity, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 71, type: ACTUAL, armsInterventionsModule interventions name: Intrathecal morphine administered group, Four quadrant transversus abdominis plane block applied group, outcomesModule primaryOutcomes measure: postoperative numerical rating scale, secondaryOutcomes measure: postoperative opioid use, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Başakşehir Çam and Sakura City Hospital, city: Istanbul, state: Basaksehir, country: Turkey, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06382350, orgStudyIdInfo id: KHL-002-2024, briefTitle: Glycemic Excursions in Patients With Type 1 Diabetes Mellitus Using Closed-loop Systems, acronym: SAFEDRIVE, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-09, completionDateStruct date: 2026-05, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: University Hospital, Motol, class: OTHER, descriptionModule briefSummary: The study aims to compare glycemic excursions during several life situations (such as periods of driving, periods of night sleep, periods of occupation, periods of physical activity, and periods of stress) in patients with type 1 diabetes treated with closed-loop system and multiple daily insulin dose therapy, conditionsModule conditions: Type 1 Diabetes Mellitus, conditions: Type 1 Diabetes Mellitus With Hypoglycemia, conditions: Drive, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: MiniMed 780 G, outcomesModule primaryOutcomes measure: The frequency of hypoglycemia (<3.9 mmol/l) during the driving periods, secondaryOutcomes measure: Period of time spent in a range between 3.9 and 4.5 mmol/l (a risky period) during driving., otherOutcomes measure: Specific CGM analysis in relation to recorded the daily activities, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06382337, orgStudyIdInfo id: A03010240S, briefTitle: Immediate Dental Implants in The Upper Anterior Region, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-21, primaryCompletionDateStruct date: 2025-03, completionDateStruct date: 2025-04, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Mansoura University, class: OTHER, descriptionModule briefSummary: The aim of the study will be to evaluate maxillary anterior teeth replacement with immediate dental implant utilizing vestibular socket therapy versus ice cream cone technique both clinically and radiographically., conditionsModule conditions: Teeth Loss, conditions: Alveolar Bone Resorption, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 16, type: ESTIMATED, armsInterventionsModule interventions name: Group A : ice cream cone technique, interventions name: Group B : the vestibular socket therapy, outcomesModule primaryOutcomes measure: Bone changes, secondaryOutcomes measure: soft tissue changes, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Faculty of Dentistry Mansoura University, city: Mansoura, zip: 7650001, country: Egypt, contacts role: CONTACT, phone: 050 2248512, email: dentfac@mans.edu.eg, contacts name: Mohamed Fa Shoeib, demonstrator, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 31.03637, lon: 31.38069, hasResults: False
protocolSection identificationModule nctId: NCT06382285, orgStudyIdInfo id: 0206-22-ASF, briefTitle: The Effect of a Prolonged Peripheral Nerve Block on the Level of Pain After a Knee Replacement, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-10-30, primaryCompletionDateStruct date: 2025-10-30, completionDateStruct date: 2026-01-31, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Assaf-Harofeh Medical Center, class: OTHER_GOV, descriptionModule briefSummary: The aim of this study is to examine the effect of a prolonged peripheral nerve block (utilizing continuous adductor canal block) on the level of pain after a knee replacement surgery, conditionsModule conditions: Knee Replacement Surgery, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The study will include 50 patients who underwent a knee replacement surgery, who will be randomized to 2 groups. 6 hours after surgery the two groups will be connected to a prolonged block pump. One group will receive the peripheral block ropivacaine 0.2% according to the protocol of 8-10 cc per hour up to 24 hours after surgery. The second group will receive saline according to the same protocol, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Continues peripheral block, outcomesModule primaryOutcomes measure: Pain level, primaryOutcomes measure: Analgesic use, secondaryOutcomes measure: Physiotherapy, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06382272, orgStudyIdInfo id: IRB23-2027, briefTitle: [Trial of device that is not approved or cleared by the U.S. FDA], statusModule overallStatus: WITHHELD, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: [Redacted], hasResults: False
protocolSection identificationModule nctId: NCT06382259, orgStudyIdInfo id: H24-Acute-Movement-Breaks, briefTitle: The Acute Effect of Movement Breaks on Glycemic Responses in Individuals With Type 2 Diabetes, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-19, primaryCompletionDateStruct date: 2025-07-15, completionDateStruct date: 2025-07-15, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: University of British Columbia, class: OTHER, collaborators name: McMaster University, descriptionModule briefSummary: To conduct a randomized crossover trial to determine the acute impact of low-intensity movement breaks on glycemic control in physically inactive individuals living with type 2 diabetes using continuous glucose monitoring., conditionsModule conditions: Type 2 Diabetes, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Movement breaks, outcomesModule primaryOutcomes measure: Mean 24-h glucose concentration determined using continuous glucose monitoring assessed using continuous glucose monitoring, secondaryOutcomes measure: Time in range determined using continuous glucose monitoring, secondaryOutcomes measure: Time above range determined using continuous glucose monitoring, secondaryOutcomes measure: Time below range determined using continuous glucose monitoring, secondaryOutcomes measure: Glycemic variability determined using continuous glucose monitoring, secondaryOutcomes measure: Two-hour glucose area under the curve following standardized breakfast, lunch and dinner meals, eligibilityModule sex: ALL, minimumAge: 30 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06382246, orgStudyIdInfo id: H24-Acute-ExSnacks, briefTitle: The Acute Effect of "Exercise Snacks" on Glycemic Responses in Individuals With Type 2 Diabetes, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-19, primaryCompletionDateStruct date: 2025-07-15, completionDateStruct date: 2025-07-15, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: University of British Columbia, class: OTHER, collaborators name: McMaster University, descriptionModule briefSummary: To conduct a randomized crossover trial to determine the acute impact of exercise snacks on glycemic control in physically inactive individuals living with type 2 diabetes using continuous glucose monitoring., conditionsModule conditions: Type 2 Diabetes, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: Randomized controlled crossover design, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Exercise snacks, outcomesModule primaryOutcomes measure: Mean 24-h glucose concentration determined using continuous glucose monitoring assessed using continuous glucose monitoring, secondaryOutcomes measure: Time in range determined using continuous glucose monitoring, secondaryOutcomes measure: Time above range determined using continuous glucose monitoring, secondaryOutcomes measure: Time below range determined using continuous glucose monitoring, secondaryOutcomes measure: Glycemic variability determined using continuous glucose monitoring, secondaryOutcomes measure: Two-hour glucose area under the curve following standardized breakfast, lunch and dinner meals, eligibilityModule sex: ALL, minimumAge: 30 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06382207, orgStudyIdInfo id: HM20029298, briefTitle: Effectiveness of the Eko Digital Stethoscope in Capturing Infant ECGs, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Virginia Commonwealth University, class: OTHER, collaborators name: Eko Devices, Inc., descriptionModule briefSummary: When a newborn is diagnosed with tachyarrhythmia, they are generally started on medical therapies, most commonly a beta-blocker, while being observed in an inpatient setting. In most academic institutions, current practice is to provide parental teaching on use of a stethoscope to auscultate their child when there is suspicion for distress, in addition to requiring cardiopulmonary resuscitation (CPR) classes. Fortunately, newer technologies have emerged that allow for capture of cardiac rhythm that may provide a buffer between the infant and the emergency room., conditionsModule conditions: Tachyarrhythmia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: This proof-of-concept study will enroll infants, defined as individuals \<1 year of age. It will assess the feasibility and effectiveness of a physician and parent/caregiver in using the Eko DUO and CORE 500 to capture ECGs in patients \<10 kg in a clinic and home setting., primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Eko Duo electronic stethoscope, interventions name: CORE 500 electronic stethoscope, outcomesModule primaryOutcomes measure: Number and proportion of good-quality ECG recordings taken by physicians, for DUO and for CORE 500, primaryOutcomes measure: Number and proportion of good-quality ECG recordings taken by parents/caregivers, with a physician present in the exam room using the CORE 500, primaryOutcomes measure: Number and proportion of good-quality ECG recordings taken by parents/caregivers, with a physician absent from the exam room, for CORE 500, primaryOutcomes measure: Number and proportion of good-quality ECG recordings taken by parents/caregivers, at home, for CORE 500 only, eligibilityModule sex: ALL, maximumAge: 1 Year, stdAges: CHILD, contactsLocationsModule locations facility: Virginia Commonwealth University, city: Richmond, state: Virginia, zip: 23298, country: United States, geoPoint lat: 37.55376, lon: -77.46026, hasResults: False
protocolSection identificationModule nctId: NCT06382194, orgStudyIdInfo id: STUDY00014522, secondaryIdInfos id: 1R21AG076362-01, type: NIH, link: https://reporter.nih.gov/quickSearch/1R21AG076362-01, briefTitle: Decision Making Tool for Firearm Storage, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-06-30, completionDateStruct date: 2024-07-31, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: University of Washington, class: OTHER, collaborators name: National Institute on Aging (NIA), descriptionModule briefSummary: This is a one-arm pilot study testing the feasibility and acceptability of a decision aid about safe firearm storage., conditionsModule conditions: Dementia, Mild, conditions: Depression, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 66, type: ESTIMATED, armsInterventionsModule interventions name: Decision aid, outcomesModule primaryOutcomes measure: Firearm storage (adapted from the National Firearm Survey), secondaryOutcomes measure: Low-Literacy Decisional Conflict Scale, secondaryOutcomes measure: Knowledge Questionnaire, secondaryOutcomes measure: Feasibility of intervention delivery, secondaryOutcomes measure: Acceptability of Intervention Measure, eligibilityModule sex: ALL, minimumAge: 65 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Washington, status: RECRUITING, city: Seattle, state: Washington, zip: 98104, country: United States, contacts name: Rachel Ross, MPH, role: CONTACT, phone: 509-596-1438, email: rross4@uw.edu, contacts name: Elizabeth A Phelan, MD, role: PRINCIPAL_INVESTIGATOR, contacts name: Laura Prater, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 47.60621, lon: -122.33207, hasResults: False