protocolSection identificationModule nctId: NCT06372496, orgStudyIdInfo id: 219912, briefTitle: Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-16, primaryCompletionDateStruct date: 2026-03-11, completionDateStruct date: 2026-03-11, studyFirstPostDateStruct date: 2024-04-18, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: GlaxoSmithKline, class: INDUSTRY, descriptionModule briefSummary: The goal of this study is to assess and compare the effectiveness of fluticasone furoate/umeclidinium bromide/vilanterol trifenatate (FF/UMEC/VI) with inhaled corticosteroids/long-acting beta-2 agonists (ICS/LABA) in adult participants with uncontrolled asthma, conditionsModule conditions: Asthma, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 1136, type: ESTIMATED, armsInterventionsModule interventions name: Fluticasone furoate/umeclidinium bromide/vilanterol trifenatate, interventions name: Inhaled corticosteroids/long-acting beta-2 agonists, outcomesModule primaryOutcomes measure: Change from baseline in trough forced expiratory volume in 1 second (FEV1), secondaryOutcomes measure: Number of participants achieving ≥0.5 point improvement from baseline for the Asthma Control Questionnaire-7 (ACQ-7) after 24 weeks of treatment, secondaryOutcomes measure: Number of participants achieving the composite endpoint at Week in participants after 52 weeks of treatment, secondaryOutcomes measure: Change from baseline in trough forced expiratory volume in 1 second (FEV1) after 52 weeks of treatment, secondaryOutcomes measure: Number of participants achieving ≥0.5 point improvement from baseline for the ACQ-7 after 52 weeks of treatment, secondaryOutcomes measure: Number of participants achieving ≥0.5 point improvement from baseline for the Asthma Control Questionnaire-6 (ACQ-6) after 24 and 52 weeks of treatment, secondaryOutcomes measure: Number of participants achieving ≥0.5 point improvement from baseline for the ACQ-5 after 24 and 52 weeks of treatment, secondaryOutcomes measure: Change from baseline in the ACQ-7 total score after 24 and 52 weeks of treatment, secondaryOutcomes measure: Change from baseline in the ACQ-5 total score after 24 and 52 weeks of treatment, secondaryOutcomes measure: Change from baseline in the ACQ-6 total score after 24 and 52 weeks of treatment, secondaryOutcomes measure: Change from baseline in the Asthma Control Test (ACT) score after 24 and 52 weeks of treatment, secondaryOutcomes measure: Number of participants achieving the composite endpoint among those on budesonide/formoterol prior to randomization, secondaryOutcomes measure: Change from baseline in the Asthma Quality of Life Questionnaire (AQLQ-12) total scores after 24 and 52 weeks of treatment, secondaryOutcomes measure: Change from baseline in the Asthma Quality of Life Questionnaire (AQLQ-12) domain scores after 24 and 52 weeks of treatment, secondaryOutcomes measure: Change from baseline in the four domains of the asthma-specific adaptation of the Work Productivity and Activity Impairment Questionnaire (WPAI:Asthma) after 24 and 52 weeks of treatment, secondaryOutcomes measure: Change from baseline in trough forced expiratory volume in 1 second (FEV1) among participants on budesonide/formoterol prior to randomization, secondaryOutcomes measure: Number of participants achieving ≥0.5 points improvement from baseline for ACQ-7 among participants on budesonide/formoterol prior to randomization, secondaryOutcomes measure: Change from baseline in the ACQ-7 total score among participants on budesonide/formoterol prior to randomization, secondaryOutcomes measure: Change from baseline in trough forced expiratory volume in 1 second (FEV1) for participants with no treatment prior to randomization., secondaryOutcomes measure: Number of participants achieving ≥0.5 points improvement from baseline for ACQ-7 for participants with no treatment prior to randomization., secondaryOutcomes measure: Change from baseline in the ACQ-7 total score for participants with no treatment prior to randomization., eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: GSK Investigational Site, city: Little Rock, state: Arkansas, zip: 72205, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Karl V Sitz, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 34.74648, lon: -92.28959, locations facility: GSK Investigational Site, city: Newport Beach, state: California, zip: 92663, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Ryan Mitchell Klein, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 33.61891, lon: -117.92895, locations facility: GSK Investigational Site, city: Miami, state: Florida, zip: 33135, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Enrique Villa, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 25.77427, lon: -80.19366, locations facility: GSK Investigational Site, city: Miami, state: Florida, zip: 33173, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Ileana C. Rodicio, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 25.77427, lon: -80.19366, locations facility: GSK Investigational Site, city: Miami, state: Florida, zip: 33173, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Jaime Landman, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 25.77427, lon: -80.19366, locations facility: GSK Investigational Site, city: Orlando, state: Florida, zip: 32819, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Marvin Heuer, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 28.53834, lon: -81.37924, locations facility: GSK Investigational Site, city: Port Charlotte, state: Florida, zip: 33952, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Joseph Ravid, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 26.97617, lon: -82.09064, locations facility: GSK Investigational Site, city: Tallahassee, state: Florida, zip: 32308, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Ronald H. Saff, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 30.43826, lon: -84.28073, locations facility: GSK Investigational Site, city: Columbus, state: Georgia, zip: 31904, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Robert R Chrzanowski, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 32.46098, lon: -84.98771, locations facility: GSK Investigational Site, city: Normal, state: Illinois, zip: 61761, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Dareen Siri, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 40.5142, lon: -88.99063, locations facility: GSK Investigational Site, city: Bangor, state: Maine, zip: 04401, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Paul Alan Shapero, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 44.80118, lon: -68.77781, locations facility: GSK Investigational Site, city: Columbia, state: Maryland, zip: 21044, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: David Nyanjom, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 39.24038, lon: -76.83942, locations facility: GSK Investigational Site, city: Brick, state: New Jersey, zip: 08724, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Bruce DeCotiis, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 40.05928, lon: -74.13708, locations facility: GSK Investigational Site, city: Linwood, state: New Jersey, zip: 08221, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Allen Silvey, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 39.33984, lon: -74.57516, locations facility: GSK Investigational Site, city: New Windsor, state: New York, zip: 12553, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Sashi Makam, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 41.47676, lon: -74.02375, locations facility: GSK Investigational Site, city: Asheville, state: North Carolina, zip: 28801, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: David Cypcar, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 35.60095, lon: -82.55402, locations facility: GSK Investigational Site, city: Charlotte, state: North Carolina, zip: 28273, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Emeka M Eziri, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 35.22709, lon: -80.84313, locations facility: GSK Investigational Site, city: Greenville, state: North Carolina, zip: 27834, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Bryan Dunn, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 35.61266, lon: -77.36635, locations facility: GSK Investigational Site, city: Raleigh, state: North Carolina, zip: 27607, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Craig F LaForce, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 35.7721, lon: -78.63861, locations facility: GSK Investigational Site, city: Winston-Salem, state: North Carolina, zip: 27104, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Wendy C Moore, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 36.09986, lon: -80.24422, locations facility: GSK Investigational Site, city: Cincinnati, state: Ohio, zip: 45231, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: David I Bernstein, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 39.12713, lon: -84.51435, locations facility: GSK Investigational Site, city: Philadelphia, state: Pennsylvania, zip: 19107, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Sadia Benzaquen, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 39.95233, lon: -75.16379, locations facility: GSK Investigational Site, city: Philadelphia, state: Pennsylvania, zip: 19140, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Kartik Shenoy, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 39.95233, lon: -75.16379, locations facility: GSK Investigational Site, city: Pittsburgh, state: Pennsylvania, zip: 15241, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Michael J. Palumbo, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 40.44062, lon: -79.99589, locations facility: GSK Investigational Site, city: Rock Hill, state: South Carolina, zip: 29732, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Michael Denenberg, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 34.92487, lon: -81.02508, locations facility: GSK Investigational Site, city: Spartanburg, state: South Carolina, zip: 29303, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Farhan Siddiqui, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 34.94957, lon: -81.93205, locations facility: GSK Investigational Site, city: Dallas, state: Texas, zip: 75246, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Mark W Millard, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 32.78306, lon: -96.80667, locations facility: GSK Investigational Site, city: Kerrville, state: Texas, zip: 78028, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Dale E Mohar, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 30.04743, lon: -99.14032, locations facility: GSK Investigational Site, city: Waco, state: Texas, zip: 76712, country: United States, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Niran J. Amar, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 31.54933, lon: -97.14667, locations facility: GSK Investigational Site, city: Ciudad Autónoma de Buenos Aires, state: Buenos Aires, zip: C1192AAW, country: Argentina, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Ana Maria Stok, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -34.61315, lon: -58.37723, locations facility: GSK Investigational Site, city: Florencio Varela, state: Buenos Aires, zip: 1888, country: Argentina, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Andrea Cintia Medina, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -34.82722, lon: -58.39556, locations facility: GSK Investigational Site, city: Mar del Plata, state: Buenos Aires, zip: 7600, country: Argentina, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Luis Wehbe, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -38.00228, lon: -57.55754, locations facility: GSK Investigational Site, city: Cordoba, state: Córdova, zip: X5003DCE, country: Argentina, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Victor Hugo Cambursano, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -31.4135, lon: -64.18105, locations facility: GSK Investigational Site, city: Rosario, state: Santa Fe, zip: 2000, country: Argentina, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Adriana M. Marcipar, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -32.94682, lon: -60.63932, locations facility: GSK Investigational Site, city: Rosario, state: Santa Fe, zip: S2000DBS, country: Argentina, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Ledit R F Ardusso, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -32.94682, lon: -60.63932, locations facility: GSK Investigational Site, city: Ciudad Autonoma de Buenos Aires, zip: C1425BEN, country: Argentina, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Anahi Yanez, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -34.61315, lon: -58.37723, locations facility: GSK Investigational Site, city: Mendoza, zip: 5500, country: Argentina, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Pablo Saez Scherbovsky, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -32.89084, lon: -68.82717, locations facility: GSK Investigational Site, city: Rosario, zip: 2000, country: Argentina, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Gabriel Gattolin, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -32.94682, lon: -60.63932, locations facility: GSK Investigational Site, city: Bruce, state: Australian Capital Territory, zip: 2617, country: Australia, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Amber Leah, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -32.46667, lon: 138.2, locations facility: GSK Investigational Site, city: Blacktown, state: New South Wales, zip: 2148, country: Australia, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Rahul Mohan, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -33.76667, lon: 150.91667, locations facility: GSK Investigational Site, city: Campbelltown, state: New South Wales, zip: 2560, country: Australia, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Belinda Cochrane, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -34.06667, lon: 150.81667, locations facility: GSK Investigational Site, city: Coffs Harbour, state: New South Wales, zip: 2450, country: Australia, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Olga O Voloshyna, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -30.29626, lon: 153.11351, locations facility: GSK Investigational Site, city: Kanwal, state: New South Wales, zip: 2259, country: Australia, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Dominic Douglas, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -33.253, lon: 151.4911, locations facility: GSK Investigational Site, city: Brisbane, state: Queensland, zip: 4006, country: Australia, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Esmond Leong, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -27.46794, lon: 153.02809, locations facility: GSK Investigational Site, city: Spearwood, state: Western Australia, zip: 6163, country: Australia, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Peter R Bremner, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: -32.10534, lon: 115.77797, locations facility: GSK Investigational Site, city: Brampton, state: Ontario, zip: L6T 0G1, country: Canada, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Naresh K. Aggarwal, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 43.68341, lon: -79.76633, locations facility: GSK Investigational Site, city: Windsor, state: Ontario, zip: N8X 1T3, country: Canada, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Syed Anees, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 42.30008, lon: -83.01654, locations facility: GSK Investigational Site, city: Trois-Rivieres, state: Quebec, zip: G9A 4P3, country: Canada, contacts name: US GSK Clinical Trials Call Center, role: CONTACT, phone: 877-379-3718, email: GSKClinicalSupportHD@gsk.com, contacts name: EU GSK Clinical Trials Call Centre, role: CONTACT, phone: +44 (0) 20 8990 4466, email: GSKClinicalSupportHD@gsk.com, contacts name: Patrice Gauthier, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 46.34515, 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