protocolSection identificationModule nctId: NCT06269081, orgStudyIdInfo id: R01NR020770, type: NIH, link: https://reporter.nih.gov/quickSearch/R01NR020770, secondaryIdInfos id: R01NR020770, type: NIH, link: https://reporter.nih.gov/quickSearch/R01NR020770, briefTitle: Testing Two Interventions to Improve Health Outcomes and Quality of Life Among Rural Older Adults Living With HIV, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-08, primaryCompletionDateStruct date: 2027-01-31, completionDateStruct date: 2027-01-31, studyFirstPostDateStruct date: 2024-02-21, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Medical College of Wisconsin, class: OTHER, collaborators name: National Institute of Nursing Research (NINR), descriptionModule briefSummary: Engagement in HIV medical care and adherence to HIV medications are both essential in improving health outcomes among people living with HIV (PLH), but PLH living in rural areas-who suffer higher mortality rates than their urban counterparts-can confront multiple barriers to care engagement and adherence, especially as they face the logistical, medical, and social challenges associated with aging. This project will test the efficacy of two interventions to determine their impact on HIV health outcomes and quality of life among rural, older PLH living in the Southern U.S. The two interventions, adapted from evidence-based interventions and delivered remotely, are: (1) supportive-expressive peer social support groups and (2) strengths-based case management. We hypothesize that both interventions will increase viral suppression, antiretroviral therapy adherence, and health-related quality of life and decrease depressive symptoms. Results from this study will provide us with tools to improve health outcomes for rural older people living with HIV., conditionsModule conditions: HIV, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: FACTORIAL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 352, type: ESTIMATED, armsInterventionsModule interventions name: Supportive-Expressive Peer Social Support Group Intervention, interventions name: Individual Strengths-Based Case Management Intervention, outcomesModule primaryOutcomes measure: Viral Suppression, primaryOutcomes measure: Antiretroviral Treatment Medication Adherence, primaryOutcomes measure: Health-Related Quality of Life, primaryOutcomes measure: Depressive Symptoms, secondaryOutcomes measure: Social Support, secondaryOutcomes measure: Loneliness, secondaryOutcomes measure: Internalized HIV Stigma, secondaryOutcomes measure: General Self-Efficacy, secondaryOutcomes measure: HIV Treatment Adherence Self-Efficacy, secondaryOutcomes measure: Accessing Needed Social and Medical Services, secondaryOutcomes measure: Structural Barriers, eligibilityModule sex: ALL, minimumAge: 50 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Center for AIDS Intervention Research, Medical College of Wisconsin, status: RECRUITING, city: Milwaukee, state: Wisconsin, zip: 53202, country: United States, contacts name: Jennifer Walsh, role: CONTACT, phone: 414-955-7710, email: jwalsh@mcw.edu, geoPoint lat: 43.0389, lon: -87.90647, hasResults: False