hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06300801, orgStudyIdInfo id: 2023-48, briefTitle: Postoperative Pancreatic Fistula in Patients Undergoing Pancreaticoduodenectomy, acronym: popf, statusModule overallStatus: NO_LONGER_AVAILABLE, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Erol Olcok Corum Training and Research Hospital, class: OTHER, descriptionModule briefSummary: Pancreaticoduodenectomy (PD) is a complex procedure performed in patients with malignant or benign tumors of the pancreatic head and periampullary region, associated with high morbidity and mortality. Postoperative pancreatic fistula (POPF) is the most common and clinically significant complication following PD. In this study, the investigators aim to predict pancreatic fistula using the C-reactive protein-albumin ratio (CAR). The total number of participants expected to be included in this research comprises patients who underwent PD between 2017 and 2023 and developed pancreatic fistula. The participants invitation is based on the detection of a pancreatic fistula. This study is conducted for research purposes and participation is voluntary. No interventions will be performed on the participants as part of this study; however, we have prepared this form to obtain participant permission to gather certain information. If the participants consent to the use of information for scientific purposes with the guarantee of confidentiality, they will be asked to sign a consent form., conditionsModule conditions: Pancreatic Fistula After Pancreaticoduodenectomy, conditions: C-Reactive Protein, conditions: Albumin, designModule studyType: EXPANDED_ACCESS, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06300788, orgStudyIdInfo id: 23-AOI-02, briefTitle: Inorganic Pyrophosphate Homeostasis (PPi) in Pediatric Chronic Kidney Disease, acronym: PPi-DIA, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-10-01, completionDateStruct date: 2024-10-01, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Centre Hospitalier Universitaire de Nice, class: OTHER, descriptionModule briefSummary: The investigator aim to identify the role of inorganic pyrophosphate and other anti-calcifying molecules in vascular disease in children with chronic kidney disease, with a view to developing therapeutic approaches aimed at limiting the onset of vasculopathy., conditionsModule conditions: Pyrophosphate, Fetuin A, IL1, IL6, TNFalpha, Control, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: SINGLE_GROUP, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: PPI and T50 dosing, outcomesModule primaryOutcomes measure: Plasma pyrophosphate concentration [PPi]pl in children with CKD, secondaryOutcomes measure: Plasma pyrophosphate [PPi]pl concentration in children with renal transplantation, secondaryOutcomes measure: Markers of phosphocalcic metabolism, secondaryOutcomes measure: Urinary PPi concentration, secondaryOutcomes measure: Markers of vascular damage in CKD, eligibilityModule sex: ALL, minimumAge: 0 Years, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: CHU Nice - Hôpital de l'Archet 2, city: Nice, state: Alpes-Mritimes, zip: 06300, country: France, contacts name: Julie BERNARDOR, role: CONTACT, phone: 04.92.03.63.65, phoneExt: +33, email: bernardor.j@chu-nice.fr, geoPoint lat: 43.70313, lon: 7.26608, hasResults: False
protocolSection identificationModule nctId: NCT06300775, orgStudyIdInfo id: 123789, briefTitle: Evaluation of Modified Hyrax Versus Quad Helix in Treatment of Posterior Cross Bite, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2025-05-01, completionDateStruct date: 2025-06-01, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: This study will be performed to evaluate the treatment of posterior cross-bite with modified hyrax \& Quad helix appliances and to compare which one will provide better results in relation to chewing difficulty in children with posterior cross- bite in mixed dentition, conditionsModule conditions: Posterior Cross Bite, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Modified Hyrax Versus Quad Helix, primaryPurpose: TREATMENT, maskingInfo masking: NONE, maskingDescription: no Masking, enrollmentInfo count: 10, type: ESTIMATED, armsInterventionsModule interventions name: modified hyrax, interventions name: quad helix, outcomesModule primaryOutcomes measure: Chewing difficulty, eligibilityModule sex: ALL, minimumAge: 6 Years, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Cairo univeristry, status: RECRUITING, city: Cairo, country: Egypt, contacts name: ola mostafa, prof, role: CONTACT, phone: 01006030036, email: ola.omar@dentistry.cu.edu.eg, contacts name: rasha adel, lecture, role: CONTACT, phone: 01007505888, email: rasha.adel@dentistry.cu.edu.com, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06300762, orgStudyIdInfo id: C3079, briefTitle: RCT Exudate Management Cutimed Sorbion Product Range, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-07-01, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2025-06-30, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: BSN Medical GmbH, class: INDUSTRY, descriptionModule briefSummary: The fluid handling capacity of superabsorbent dressings varies depending on the design and construction. The use of effective advanced wound dressings is a promising strategy to achieve adequate absorption of wound exudate and malodour promoting wound healing. The aim of the current study is to determine whether there is a difference in the clinical performance of exudate absorption with two commonly used CE-marked superabsorbent dressings when used on VLUs in routine wound care.As primary objective the dressing´s absorption performance and its ability to prevent skin maceration and leakage of the wound dressing will be investigated., conditionsModule conditions: Venous Leg Ulcer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: Two assessors are blinded to evaluate some outcomes, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 152, type: ESTIMATED, armsInterventionsModule interventions name: Superabsorbent dressing application, outcomesModule primaryOutcomes measure: Exudate management performance, secondaryOutcomes measure: Dressing change frequency, secondaryOutcomes measure: Moisture-associated skin damages, secondaryOutcomes measure: Occurrence clinical relevant peri-wound skin changes, secondaryOutcomes measure: Changes in wound tissue and general wound pain, secondaryOutcomes measure: Need for debridement after product removal, secondaryOutcomes measure: Patient satisfaction with treatment and product, secondaryOutcomes measure: HCP satisfaction with treatment and product, secondaryOutcomes measure: Changes in quality of life using the "Wound-QoL 14" (short questionnaire measuring quality of life in patients with chronic wounds based on three established disease-specific instruments), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Niels Stensen Klinik, Christliches-Klinikum-Melle, city: Melle, state: Niedersachsten, zip: 49624, country: Germany, contacts name: Jan Heggemann, role: CONTACT, contacts name: Sabine Guth, role: CONTACT, geoPoint lat: 52.20197, lon: 8.33826, hasResults: False
protocolSection identificationModule nctId: NCT06300749, orgStudyIdInfo id: LE-CCM, briefTitle: Effectiveness of Chiropractic Cervical Manipulation in Lateral Epicondylitis, statusModule overallStatus: COMPLETED, startDateStruct date: 2018-10-30, primaryCompletionDateStruct date: 2019-01-03, completionDateStruct date: 2019-01-03, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Mesut Arslan, class: OTHER, descriptionModule briefSummary: İt is aimed to examine the effect of chiropractic cervical manipulation on pain, functionality and grip strength in patients with lateral epicondylitis and whether it is preferable to placebo., conditionsModule conditions: Lateral Epicondylitis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 50, type: ACTUAL, armsInterventionsModule interventions name: Chiropractic Cervical Manipulation, interventions name: Sham Technique Practice, outcomesModule primaryOutcomes measure: Numerical Pain Scale (NPS), primaryOutcomes measure: Grip Strength, primaryOutcomes measure: Patient Rated Tennis Elbow Evaluation (PRTEE), eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule locations facility: Bitlis Eren University, city: Bitlis, zip: 13000, country: Turkey, geoPoint lat: 38.40115, lon: 42.10784, hasResults: False
protocolSection identificationModule nctId: NCT06300736, orgStudyIdInfo id: 2023PI247, briefTitle: Design of a Predictive Score for Contamination of Pediatric Blood Cultures, acronym: HEPIC, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2022-01-01, primaryCompletionDateStruct date: 2024-10-01, completionDateStruct date: 2024-10-01, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Central Hospital, Nancy, France, class: OTHER, descriptionModule briefSummary: The contamination rate for blood cultures is high in pediatrics, due to different sampling techniques and the difficulty of sampling small-weight children, thus favoring contamination of the devices at the time of sampling. It is also more difficult to distinguish contamination from true bacteremia in children at an early stage, notably due to the limited number of vials that can be taken at any one time.On a daily basis, clinicians are faced with the choice of whether or not to initiate probabilistic antibiotic therapy when faced with the result of a positive blood culture, particularly when identification is not yet available, but only direct examination.Contamination has major consequences for patient management. Studies in adults have shown that contamination increases hospital length of stay by 4 to 5 days, laboratory costs by +20% and recourse to intravenous antibiotic therapy by +39%. In children, studies came to the same conclusion, with greater prescription of antibiotics, particularly intravenous antibiotics, in patients with contaminated blood cultures than in patients with sterile blood cultures. It also showed that 26% of patients with contaminated blood cultures were initially hospitalized because of the positivity of this test.The aim of this research is to determine the factors associated with contamination, in order to create a predictive score that would help clinicians in their decision-making when receiving the blood culture result as "positive"., conditionsModule conditions: Bacteremia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 200, type: ESTIMATED, outcomesModule primaryOutcomes measure: Blood culture diagnosis, secondaryOutcomes measure: Score performance, eligibilityModule sex: ALL, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: CHRU Nancy, city: Nancy, zip: 54000, country: France, geoPoint lat: 48.68439, lon: 6.18496, hasResults: False
protocolSection identificationModule nctId: NCT06300723, orgStudyIdInfo id: 2024-BRL-101-SCD-01, briefTitle: Clinical Study of BRL-101 in Severe SCD, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-25, primaryCompletionDateStruct date: 2026-03-20, completionDateStruct date: 2026-06-15, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Bioray Laboratories, class: INDUSTRY, collaborators name: First Affiliated Hospital of Guangxi Medical University, descriptionModule briefSummary: This is a single center, non-randomized, open label, single-dose study in subjects with Sickle Cell Disease (SCD). The study will evaluate the safety and efficacy of autologous CRISPR-Cas9 modified CD34+ human hematopoietic stem and progenitor cells (hHSPCs) (BRL-101)., conditionsModule conditions: Sickle Cell Disease, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 1, type: ESTIMATED, armsInterventionsModule interventions name: BRL-101, outcomesModule primaryOutcomes measure: Proportion of stem cell engrafted subjects, primaryOutcomes measure: Time to neutrophil engraftment, primaryOutcomes measure: Frequency, severity, and relationship to BRL-101 of adverse events over 12 months following BRL-101 infusion, eligibilityModule sex: ALL, minimumAge: 3 Years, maximumAge: 35 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: First Affiliated Hospital of Guangxi Medical University, city: Nanning, state: Guangxi, zip: 530021, country: China, contacts name: Yongrong Lai, phD, role: CONTACT, email: laiyongrong@hotmail.com, geoPoint lat: 22.81667, lon: 108.31667, hasResults: False
protocolSection identificationModule nctId: NCT06300710, orgStudyIdInfo id: CPR in PICU, briefTitle: Outcomes and Risk Factors of CPR in PICU, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-02-01, completionDateStruct date: 2025-03-01, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: 1. To detect the frequency and the underlying causes of cardiopulmonary arrest .2. To detect outcome of CPR3. To identify the associated risk factors for the different outcomes after CPR among those patients, conditionsModule conditions: Cardio Respiratory Arrest, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: RETROSPECTIVE, enrollmentInfo count: 30, type: ESTIMATED, outcomesModule primaryOutcomes measure: incidence of cardiac arrest and survival to discharge from the PICU (dead versus alive), secondaryOutcomes measure: Rate of risk factors associated with outcome of CPR, eligibilityModule sex: ALL, minimumAge: 1 Month, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06300697, orgStudyIdInfo id: HUM00235532, briefTitle: Michigan Food and Atopic Dermatitis (M-FAD) Program - Molecular Analytics Project, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-15, primaryCompletionDateStruct date: 2027-03, completionDateStruct date: 2027-03, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-04-11, sponsorCollaboratorsModule leadSponsor name: University of Michigan, class: OTHER, descriptionModule briefSummary: This study will explore potential links between atopic dermatitis and food allergy. This information will be useful to determine atopic dermatitis and food allergy share unique biochemical or genetic identifiers useful for diagnosing and treatments in the future.This is a mechanistic study consisting of obtaining blood and skin samples from participants at baseline. Individuals may also undergo a clinically indicated oral food challenge and have blood and skin samples collected at various times during the oral food challenge. This study will create a molecular map of the pathology of atopic dermatitis and food allergy. This information will be deployed to evaluate the hypothesis that atopic dermatitis and food allergy share unique genetic transcriptional signals in which the study team can then further analyze pathological pathways and cell types., conditionsModule conditions: Atopic Dermatitis, conditions: Food Allergy, conditions: Healthy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: Data and biospecimen collection, interventions name: Skin biopsies, interventions name: Oral Food Challenge (OFC) procedures, outcomesModule primaryOutcomes measure: Anaphylaxis occurrence rates in each group, secondaryOutcomes measure: Anaphylaxis severity in each group, secondaryOutcomes measure: Reaction rates in each group, secondaryOutcomes measure: Anaphylaxis likelihood in each group based on the Brighton score, eligibilityModule sex: ALL, minimumAge: 10 Years, maximumAge: 55 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: University of Michigan, status: RECRUITING, city: Ann Arbor, state: Michigan, zip: 48109, country: United States, contacts name: Bridgette Kaul, RN, role: CONTACT, phone: 734-963-5634, email: bbeaupre@umich.edu, contacts name: Chase Schuler, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 42.27756, lon: -83.74088, hasResults: False
protocolSection identificationModule nctId: NCT06300658, orgStudyIdInfo id: 900/2/24, briefTitle: Stellate Ganglion Block for Preserving Arteriovenous Fistula in Hemodialysis Patients Undergoing Major Lower Limb Orthopedic Surgery, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-09, primaryCompletionDateStruct date: 2024-09-01, completionDateStruct date: 2024-09-01, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Aswan University, class: OTHER, descriptionModule briefSummary: The aim of this study is to evaluate the role of stellate ganglion blockade (SGB) for preserving arteriovenous fistula in hemodialysis patients undergoing major lower limb orthopedic surgery., conditionsModule conditions: Stellate Ganglion Block, conditions: Arteriovenous Fistula, conditions: Hemodialysis, conditions: Major Lower Limb Orthopedic Surgery, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Stellate ganglion block, outcomesModule primaryOutcomes measure: Fistula flow rate, secondaryOutcomes measure: Peak systolic velocity (PSV), secondaryOutcomes measure: End diastolic velocity (EDV), secondaryOutcomes measure: Incidence of failure, secondaryOutcomes measure: Adverse effects, eligibilityModule sex: ALL, minimumAge: 21 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Aswan University, status: RECRUITING, city: Aswan, zip: 81528, country: Egypt, contacts name: Ayman M Eldemrdash, MD, role: CONTACT, phone: 00201001296116, email: ayman.mohamady@aswu.edu.eg, contacts name: Soudy S Hammad, MD, role: SUB_INVESTIGATOR, contacts name: Tarek S Hemaida, MD, role: SUB_INVESTIGATOR, contacts name: Taha T Dardeer, MD, role: SUB_INVESTIGATOR, contacts name: Ahmed A Mohsen, MD, role: SUB_INVESTIGATOR, contacts name: Ahmed K Fathy, MD, role: SUB_INVESTIGATOR, contacts name: Gamal H Shams, MD, role: SUB_INVESTIGATOR, geoPoint lat: 24.09082, lon: 32.89942, hasResults: False
protocolSection identificationModule nctId: NCT06300645, orgStudyIdInfo id: SPLATTvsTATT in recurrent CTEV, briefTitle: SPLATT to Peroneus Brevis vs TATT to Lateral Cuneiform, acronym: Recurrent CTEV, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2024-01-17, primaryCompletionDateStruct date: 2025-03-01, completionDateStruct date: 2026-03-01, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: Congenital talipes equinovarus, is a common congenital foot deformity involving hindfoot equinus and varus, along with mid-/forefoot adduction and cavus. Currently, the Ponseti method is the preferred initial treatment for idiopathic clubfoot1. Despite the initial phase's remarkable efficacy in correcting clubfeet, there remains a notable recurrence rate after Ponseti treatment2* Numerous studies demonstrate a very high success rate during early follow-ups, ranging from 92% to 100%3* Nonetheless, recurrence remains a challenge for orthopedic surgeons. A common trigger for recurrence is the dynamic supination of the foot, which results from excessive activation of the tibialis anterior muscle during ankle dorsiflexion4Multiple studies indicate that tibialis anterior tendon transfer (TATT) is an effective tool for management of clubfoot recurrence, particularly dynamic supination5* The widely used technique involves transferring the entire tendon through a drill hole in the lateral cuneiform and anchoring it on the plantar aspect of the foot using a sewing button and felt pad6* While effective, this procedure raises the risk of pressure sores due to button placement on the sole7Split anterior tibialis tendon transfer (SPLATT) to peroneus brevis is a well-described treatment strategy of varus foot deformities in patients with neuromuscular disorders8* The technique has been reported to achieve successful deformity correction while avoiding skin problems associated with external button placement on the sole of the foot in tendon-to-bone transfers8The present study aims to assess the outcome of utilizing SPLATT to peroneus brevis procedure in the treatment of recurrent CTEV in comparison to the original total TATT to the lateral cuneiform, conditionsModule conditions: Recurrent Congenital Talipes Equinovarus, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 25, type: ESTIMATED, armsInterventionsModule interventions name: SPLATT, outcomesModule primaryOutcomes measure: Correction of recurrent congenital talipes, eligibilityModule sex: ALL, minimumAge: 4 Years, maximumAge: 12 Years, stdAges: CHILD, contactsLocationsModule locations facility: Assiut university hospital, city: Assiut, zip: 71515, country: Egypt, geoPoint lat: 27.18096, lon: 31.18368, hasResults: False