hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06302998, orgStudyIdInfo id: MS.111, briefTitle: Dexmedetomidine and Vasopressin in Septic Shock, acronym: DecatSepsis-2, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06, primaryCompletionDateStruct date: 2025-12, completionDateStruct date: 2026-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Mansoura University, class: OTHER, descriptionModule briefSummary: Rudiger and Singer suggested strategies for refining adrenergic stress (decatecholaminization). They proposed the use of dexmedetomidine and vasopressin to reduce the catecholamine load during sepsis. The investigators will use vasopressin as the primary vasopressor and a heart rate-calibrated dexmedetomidine infusion in septic shock patients.The investigators of the current study will use DEXPRESSIN in septic shock patients to investigate the effects of decatecholaminization on in-hospital mortality., conditionsModule conditions: Sepsis, conditions: Septic Shock, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized controlled superiority trial, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: The outcome assessor will be nurses - not invovled in the study - will be unware about the study drug., whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 260, type: ESTIMATED, armsInterventionsModule interventions name: DEX-PRESSIN, interventions name: Standard of Care, outcomesModule primaryOutcomes measure: in-hospital mortality, secondaryOutcomes measure: survival analysis, secondaryOutcomes measure: Norepinephrine Equivalent Dose (NED), secondaryOutcomes measure: Duration of vasopressor infusion in survivors, secondaryOutcomes measure: Initiation of invasive mechanical ventilation (IMV), secondaryOutcomes measure: Duration of IMV, secondaryOutcomes measure: Early acute kidney injury (AKI), secondaryOutcomes measure: Late acute kidney injury (AKI), secondaryOutcomes measure: Acute Physiology and Chronic Health Evaluation (APACHE-II), secondaryOutcomes measure: Simplified Acute Physiology Score (SAPS) II score, secondaryOutcomes measure: ICU length of stay, secondaryOutcomes measure: Hospital length of stay, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06302985, orgStudyIdInfo id: ICG-CLMs, briefTitle: Atomized Inhalation ICG for Treatment of Congenital Lung Malformations, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2050-12-31, completionDateStruct date: 2050-12-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Jiexiong Feng, class: OTHER, descriptionModule briefSummary: To investigate the safety and effectiveness of preoperative aerosol inhalation ICG solution for thoracoscopic accurate resection of congenital lung malformations in children., conditionsModule conditions: Pulmonary Sequestration, conditions: Congenital Pulmonary Airway Malformation, conditions: Indocyanine Green, conditions: Thoracoscopic Surgery, conditions: Children, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: atomized inhalation ICG before thoracoscope pneumonectomy, outcomesModule primaryOutcomes measure: rate residual, secondaryOutcomes measure: peak volume ratio, secondaryOutcomes measure: length of hospital stay, secondaryOutcomes measure: peak time ratio, eligibilityModule sex: ALL, minimumAge: 3 Months, maximumAge: 14 Years, stdAges: CHILD, contactsLocationsModule locations facility: Tongji Hospital, city: Wuhan, state: Hubei, zip: 430030, country: China, geoPoint lat: 30.58333, lon: 114.26667, hasResults: False
protocolSection identificationModule nctId: NCT06302972, orgStudyIdInfo id: RCRAHS-ISB/REC/MS-PT/01771, briefTitle: Effects of IASTM Along With Comprehensive Corrective Exercise Program in Upper Cross Syndrome., statusModule overallStatus: RECRUITING, startDateStruct date: 2023-10-30, primaryCompletionDateStruct date: 2024-06-30, completionDateStruct date: 2024-06-30, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-04-19, sponsorCollaboratorsModule leadSponsor name: Riphah International University, class: OTHER, descriptionModule briefSummary: This study will see the effects of IASTM along with comprehensive corrective exercise program in upper cross syndrome through their effects on pain and cervical ranges as well as postural improvement. Our study targets both male and female population. In the reference study only male population was targeted which did not show effects of both techniques on the female population though females have high stress levels which may alter results., conditionsModule conditions: Upper Cross Syndrome, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Participants were randomly assigned to the experimental group or control group after a baseline assessment with sealed enveloped method. Each participant took a envelope that identified their group and gave it to the researchers without seeing what was written. Participants were not notified which group was assigned to., primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: Participants were informed that they would receive treatment either from group 1 or group 2 without indicating which group should undergo IASTM and comprehensive corrective exercise program and which group undergo only comprehensive corrective exercise program, whoMasked: PARTICIPANT, enrollmentInfo count: 44, type: ESTIMATED, armsInterventionsModule interventions name: Traditional treatment, interventions name: IASTM and CCEP, outcomesModule primaryOutcomes measure: Range of motion Cervical (Flexion), primaryOutcomes measure: ROM Cervical (Extension), primaryOutcomes measure: ROM Cervical (Left Lateral Flexion), primaryOutcomes measure: ROM Cervical( Right Lateral Flexion), primaryOutcomes measure: ROM Cervical ( Right Rotation), primaryOutcomes measure: ROM Cervical ( Left Rotation), secondaryOutcomes measure: Numeric Pain Rating Scale (NPRS), secondaryOutcomes measure: Flexicurve Ruler and Photogrammetry for posture, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Maroof international Hospital and Railway Hospital, status: RECRUITING, city: Islamabad, state: Federal, zip: 44000, country: Pakistan, geoPoint lat: 33.72148, lon: 73.04329, hasResults: False
protocolSection identificationModule nctId: NCT06302959, orgStudyIdInfo id: 36-232 ex 23/24, briefTitle: Clock Proteins as Prognostic Markers, acronym: CLOCK-PM, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2026-03-31, completionDateStruct date: 2027-12-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: Medical University of Graz, class: OTHER, descriptionModule briefSummary: Asthma is a chronic inflammatory disease of the airways that follows a strong circadian rhythm: Signs of inflammation and symptoms worsen especially in the early morning hours. The molecular circadian clock, which is a complex machinery of transcriptional and translational feedback loops, seems to reflect the inflammatory environment of peripheral blood leukocytes. Therefore, in this observational study the investigators will monitor the molecular circadian clock in patients with severe eosinophilic asthma before and during mepolizumab treatment. Our major goal is to evaluate the potential of the molecular circadian clock to serve as a prognostic marker for disease progression, treatment response or remission in patients with severe eosinophilic asthma. The molecular circadian clock will be monitored in blood and sputum leukocytes from patients with severe eosinophilic asthma before mepolizumab treatment, after 4 month of mepolizumab therapy, and once they reach remission under mepolizumab treatment. Effects will be compared to healthy controls and patients with mild-moderate asthma without mepolizumab treatment., conditionsModule conditions: Severe Eosinophilic Asthma, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Correlation between clock expression, exacerbation rate and lung function., secondaryOutcomes measure: Correlation between clock expression, symptoms and quality of life., eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06302946, orgStudyIdInfo id: P.T.REC/012/005024, briefTitle: Effect of Neuromuscular Stimulation and Mindfulness Breathing in Patients With Stroke, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-15, primaryCompletionDateStruct date: 2025-05-30, completionDateStruct date: 2025-12-30, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: It is an interventional study in which 60 stroke patients estimated to enroll according to random allocation and divided into two groups. The experimental group will receive neuromuscular stimulation, mindfulness breathing and traditional physiotherapy while the control group will stick to traditional physiotherapy only., conditionsModule conditions: Stroke, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: neuromuscular stimulation ,mindfulness breathing and traditional physiotherapy program, interventions name: traditional physiotherapy program, outcomesModule primaryOutcomes measure: level of physical function, secondaryOutcomes measure: ventilatory function, secondaryOutcomes measure: level of stress, eligibilityModule sex: ALL, minimumAge: 50 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Faculty of Physical Therapy, status: RECRUITING, city: Cairo, state: Dokki, zip: 11432, country: Egypt, contacts name: marwa M elsayed, phd, role: CONTACT, phone: 01156033818, phoneExt: 02, email: marwadd999@gmail.com, contacts name: marwa M elsayed, ph.d, role: CONTACT, phone: 01156033818, phoneExt: 02, email: marwadd999@gmail.com, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06302920, orgStudyIdInfo id: 0001, briefTitle: Effect of Kinesiotaping on Pain,Edema and Kinesiophobia in Patients With Complex Regional Pain Syndrome, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-20, primaryCompletionDateStruct date: 2024-06-20, completionDateStruct date: 2024-12-20, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Alanya Alaaddin Keykubat University, class: OTHER, descriptionModule briefSummary: Patients will be divided into 2 groups according to the random numbers table, and both groups will receive a conventional physical therapy and rehabilitation program and nutritional support. Afterwards, edema-reducing kinesiotaping will be applied to one group. The applied kinesio tape will remain on the patient for 5 days and will be taped again after 2 days without tape. In this way, taping will be done 3 times in total, once a week for 3 weeks. During this period, patients will continue their routine physical therapy program and measurements will be taken by the same researcher in the 1st week of treatment and 3 weeks later., conditionsModule conditions: Complex Regional Pain Syndrome Type I, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Kinesiotape, outcomesModule primaryOutcomes measure: Resting pain, primaryOutcomes measure: Edema, primaryOutcomes measure: Kinesiophobia, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Alanya Alaaddin Keykubat University, city: Antalya, country: Turkey, contacts name: Deniz Bulut, role: CONTACT, phone: +90 05059445604, email: denizhava1988@gmail.com, contacts name: Deniz Bulut, role: PRINCIPAL_INVESTIGATOR, contacts name: İsmet Aslı Topcuoğlu, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 36.90812, lon: 30.69556, hasResults: False
protocolSection identificationModule nctId: NCT06302907, orgStudyIdInfo id: M/45- 14.1.2023, briefTitle: The Effect of Adding Sodium Bicarbonate 8.4% to Local Anesthesia on Pain During Upper Canine Infiltration, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2023-01-14, primaryCompletionDateStruct date: 2023-09-10, completionDateStruct date: 2024-06-30, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Al-Wataniya University, class: OTHER, descriptionModule briefSummary: The aim of the present study was to evaluate the pain during local anesthetic buccal infiltration for the maxillary canines after adding Sodium Bicarbonate 8.4% during local anesthesia., conditionsModule conditions: Local Anesthetic Complication, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Buffered Local anaesthesia, interventions name: Unbuffered Local anaesthesia, outcomesModule primaryOutcomes measure: Pain on injection, eligibilityModule sex: ALL, minimumAge: 15 Years, maximumAge: 50 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Al Wataniya Private University, city: Hama, state: Hama Government, zip: 00000, country: Syrian Arab Republic, geoPoint lat: 35.13179, lon: 36.75783, hasResults: False
protocolSection identificationModule nctId: NCT06302894, orgStudyIdInfo id: BAIBU-SBF-EC-01, briefTitle: The Effect of the Nursing Intervention Program on Adolescent Problematic Internet Users, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-10-01, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Abant Izzet Baysal University, class: OTHER, descriptionModule briefSummary: In this study; The effect of the nursing intervention program (education enriched with web 2.0 tools based on the Health Belief Model) on problematic internet use, loneliness and family harmony in adolescents who use the internet with problems will be determined., conditionsModule conditions: Internet Addiction Disorder, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 1000, type: ESTIMATED, armsInterventionsModule interventions name: Self-sufficiency, outcomesModule primaryOutcomes measure: Internet Addiction Scale, eligibilityModule sex: ALL, minimumAge: 12 Years, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Bolu Abant İzzet Baysal University Faculty of Health Sciences, city: Bolu, zip: 14300, country: Turkey, geoPoint lat: 40.73583, lon: 31.60611, hasResults: False
protocolSection identificationModule nctId: NCT06302881, orgStudyIdInfo id: liaohongfan, briefTitle: Differentiating Tumor-stroma Ratio in Pancreatic Ductal Adenocarcinoma, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2013-01, primaryCompletionDateStruct date: 2022-07, completionDateStruct date: 2024-03, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: First Affiliated Hospital of Chongqing Medical University, class: OTHER, descriptionModule briefSummary: This study introduces a novel transfer learning-based contrastive language-image pretraining adapter (CLIP-adapter) model for predicting the tumor-stroma ratio (TSR) in pancreatic ductal adenocarcinoma (PDAC) using preoperative dual-phase CT images. The primary aim is to develop an efficient and accessible tool for risk stratification and personalized treatment planning., conditionsModule conditions: Pancreatic Ductal Adenocarcinoma, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 207, type: ACTUAL, armsInterventionsModule, outcomesModule primaryOutcomes measure: The diagnostic AUC value of pancreatic ductal adenocarcinoma with deep learning algorithm., secondaryOutcomes measure: The diagnostic accuracy of pancreatic ductal adenocarcinoma with deep learning algorithm., secondaryOutcomes measure: The diagnostic sensitivity of pancreatic ductal adenocarcinoma with deep learning algorithm., secondaryOutcomes measure: The diagnostic specificity of pancreatic ductal adenocarcinoma with deep learning algorithm., secondaryOutcomes measure: The diagnostic positive predictive value of pancreatic ductal adenocarcinoma with deep learning algorithm., secondaryOutcomes measure: The diagnostic negative predictive value of pancreatic ductal adenocarcinoma with deep learning algorithm., eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06302868, orgStudyIdInfo id: 006215, secondaryIdInfos id: R43MH129065, type: NIH, link: https://reporter.nih.gov/quickSearch/R43MH129065, briefTitle: Telemedicine-Based Virtual Reality Clinic for the Treatment of Phobias, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-10-03, primaryCompletionDateStruct date: 2024-08-01, completionDateStruct date: 2024-08-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: University of South Florida, class: OTHER, collaborators name: National Institute of Mental Health (NIMH), descriptionModule briefSummary: The purpose of this study is to assess the feasibility of conducting a randomized controlled efficacy trial comparing the delivery of exposure therapy via a telemedicine-based virtual reality clinic (Doxy.me VR) vs. standard telemental health (TMH) to adults with intense fear of dogs, snakes, and/or spiders. The secondary purpose is to preliminarily examine the efficacy of using Doxy.me VR vs. TMH in reducing phobia severity., conditionsModule conditions: Arachnophobia, conditions: Cynophobia, conditions: Ophidiophobia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Telemedicine Exposure Therapy Using Photos and Videos, interventions name: Telemedicine-Based Virtual Reality Exposure Therapy, outcomesModule primaryOutcomes measure: Phobia symptom severity, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of South Florida, status: RECRUITING, city: Tampa, state: Florida, zip: 33613, country: United States, contacts name: Brian Bunnell, PhD, role: CONTACT, contacts name: Brian Bunnell, PhD, role: PRINCIPAL_INVESTIGATOR, contacts name: Triton Ong, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 27.94752, lon: -82.45843, documentSection largeDocumentModule largeDocs typeAbbrev: Prot, hasProtocol: True, hasSap: False, hasIcf: False, label: Study Protocol, date: 2023-11-21, uploadDate: 2024-01-23T13:01, filename: Prot_000.pdf, size: 451422, largeDocs typeAbbrev: ICF, hasProtocol: False, hasSap: False, hasIcf: True, label: Informed Consent Form, date: 2023-12-11, uploadDate: 2024-01-23T12:22, filename: ICF_001.pdf, size: 14053932, hasResults: False
protocolSection identificationModule nctId: NCT06302855, orgStudyIdInfo id: 2024-00124, briefTitle: Exploring Adherence and Knowledge Among Diabetic Individuals in Periodontal Care, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2026-03-01, completionDateStruct date: 2026-09-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Karim Gariani, class: OTHER, descriptionModule briefSummary: Objective(s) The primary objective is to evaluate the adherence of diabetic patients to periodontal care, accomplished either through oral communication (group A, control) or through a photograph of their smile, and focusing on their gum health evaluated by a periodontist (group B, test).Secondary objectives include assessing the prevalence of periodontal disease (PD) in this diabetic sample population and evaluating the presence of specific biomarkers related to it.The final objective is to assess the agreement between the diagnosis of periodontitis based on the photographs and the diagnosis given after the dental visit, based on the clinical examination. The aim is to determine if the photos could potentially serve as a reliable indicator for periodontal risk assessment., conditionsModule conditions: Periodontitis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 180, type: ESTIMATED, armsInterventionsModule interventions name: dental expertise, outcomesModule primaryOutcomes measure: adherence of diabetic patients to periodontal, secondaryOutcomes measure: calculate the prevalence of periodontitis, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False