hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06335511, orgStudyIdInfo id: 631-2021-OSS-AUSLBO, briefTitle: Decompression Versus Instrumented Fusion for Lumbar Degenerative Disease. Clinical and Biomechanical Outcome Study, acronym: ARCHIMEDE, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-10-10, primaryCompletionDateStruct date: 2025-02-28, completionDateStruct date: 2025-02-28, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Azienda Usl di Bologna, class: OTHER_GOV, descriptionModule briefSummary: Identification of clinical and instrumental parameters that could predict the outcome of surgical decompression of lumbar degenerative stenosis., conditionsModule conditions: Lumbar Spinal Stenosis, conditions: Degenerative Lumbar Spinal Stenosis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: microsurgical decompression, interventions name: decompression and instrumented fusion, outcomesModule primaryOutcomes measure: Short Form 12, primaryOutcomes measure: Short Form 12, primaryOutcomes measure: Short Form 12, primaryOutcomes measure: Short Form 12, primaryOutcomes measure: Visual Analogue Scale, primaryOutcomes measure: Visual Analogue Scale, primaryOutcomes measure: Visual Analogue Scale, primaryOutcomes measure: Visual Analogue Scale, primaryOutcomes measure: Oswestry Disability Index, primaryOutcomes measure: Oswestry Disability Index, primaryOutcomes measure: Oswestry Disability Index, primaryOutcomes measure: Oswestry Disability Index, primaryOutcomes measure: EuroQol-5D, primaryOutcomes measure: EuroQol-5D, primaryOutcomes measure: EuroQol-5D, primaryOutcomes measure: EuroQol-5D, primaryOutcomes measure: Postural Balance, primaryOutcomes measure: Postural Balance, primaryOutcomes measure: Postural Balance, primaryOutcomes measure: Postural Balance, primaryOutcomes measure: Locomotor performance, primaryOutcomes measure: Locomotor performance, primaryOutcomes measure: Locomotor performance, primaryOutcomes measure: Locomotor performance, primaryOutcomes measure: Spinal mobility, primaryOutcomes measure: Spinal mobility, primaryOutcomes measure: Spinal mobility, primaryOutcomes measure: Spinal mobility, secondaryOutcomes measure: Evaluation of costs, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: IRCCS Istituto Ortopedico Rizzolo, status: RECRUITING, city: Bologna, zip: 40136, country: Italy, contacts name: Giovanni Barbanti Brodano, Dr., role: CONTACT, phone: +390516366971, email: giovanni.barbantibrodano@ior.it, geoPoint lat: 44.49381, lon: 11.33875, locations facility: IRCCS Istituto delle Scienze Neurologiche di Bologna, status: RECRUITING, city: Bologna, zip: 40139, country: Italy, contacts name: Alfredo Conti, Prof., role: CONTACT, phone: 3382131017, email: alfredo.conti2@unibo.it, geoPoint lat: 44.49381, lon: 11.33875, hasResults: False
protocolSection identificationModule nctId: NCT06335498, orgStudyIdInfo id: 130-0008P, briefTitle: Further Study of AFGen1 Clinical Performance, acronym: CS3, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-04-02, primaryCompletionDateStruct date: 2024-04-12, completionDateStruct date: 2024-04-19, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-04-12, sponsorCollaboratorsModule leadSponsor name: TriVirum, Inc., class: INDUSTRY, descriptionModule briefSummary: AFGen1 is indicated for use on symptomatic or asymptomatic adults who are at risk of developing or who have atrial fibrillation, where a software assisted analysis of ambulatory ECG is needed to identify episodes of Afib. The purpose of this study is to establish further evidence for the clinical performance of AFGen1 on human participants., conditionsModule conditions: Atrial Fibrillation, conditions: Afib, conditions: ECG, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: ECG co-measurement, interventions name: Periodic ECG triggered measurement, outcomesModule primaryOutcomes measure: Bland-Altman Comparison, primaryOutcomes measure: Qualitative Evaluation, primaryOutcomes measure: Adhesive performance, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 90 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: 1808 49Th St Ct NW, city: Gig Harbor, state: Washington, zip: 98335, country: United States, geoPoint lat: 47.32926, lon: -122.58013, hasResults: False
protocolSection identificationModule nctId: NCT06335485, orgStudyIdInfo id: 2020- P123456, briefTitle: Cognitive Behavioral Therapy (CBT) Pain Prevention Intervention for Women Undergoing Surgery, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-04-01, primaryCompletionDateStruct date: 2022-09-29, completionDateStruct date: 2022-09-29, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Brigham and Women's Hospital, class: OTHER, descriptionModule briefSummary: This study investigates a Cognitive Behavioral Therapy (CBT) intervention for women who are undergoing elective surgery. The objective is to provide a toolkit of stress management techniques to decrease pain and opioid use following surgery., conditionsModule conditions: Back Pain, conditions: Cognitive Behavioral Therapy, conditions: Surgery, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Patients are randomized to either the intervention group or general group, for the intervention group patients will be randomly assigned to attend 4 weekly online virtual CBT sessions that will provide information on stress and pain reduction techniques before surgery, and 2 sessions following patient surgery., primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 32, type: ACTUAL, armsInterventionsModule interventions name: Cognitive Behavioral Therapy, outcomesModule primaryOutcomes measure: Numeric Pain Rating, secondaryOutcomes measure: Pain Medication Usage, secondaryOutcomes measure: Activity Tracking (Digital Phenotyping), eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Brigham and Women's Hospital, city: Boston, state: Massachusetts, zip: 02115, country: United States, geoPoint lat: 42.35843, lon: -71.05977, hasResults: False
protocolSection identificationModule nctId: NCT06335472, orgStudyIdInfo id: Three nerves radiofrequency, briefTitle: Three Nerves Versus Suprascapular Nerve Radiofrequency Combined With Hydrodissection in Adhesive Capsulitis, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2027-02-03, completionDateStruct date: 2027-03-05, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: comparison between effect of three nerves pulsed radiofrequency combined with hydro-dissection versus suprascapular nerve Pulsed Radiofrequency combined with hydrodissection on pain control in adhesive capsulitis within six months follow up., conditionsModule conditions: Analgesia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Ultrasound-guided effect of three nerves pulsed radiofrequency versus supra-scapular nerve pulsed radiofrequency both combined with hydro-dissection in reducing the intensity of pain in adhesive capsulitis, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: pain control and range of motion in adhesive capsulitis, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: 3 nerves pulsed radiofrequency with hydrodissection, interventions name: suprascapular nerve pulsed radiofrequency with hydrodissection, outcomesModule primaryOutcomes measure: The most effective modality on pain management of shoulder adhesive capsulitis using visual analog score., eligibilityModule sex: ALL, minimumAge: 30 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Assiut university Hospital, city: Assiut, country: Egypt, contacts name: safaa noaman, assistant lecturer, role: CONTACT, geoPoint lat: 27.18096, lon: 31.18368, hasResults: False
protocolSection identificationModule nctId: NCT06335459, orgStudyIdInfo id: Epidemiology of bunion, briefTitle: Epidemiology of Bunion and Risk Factors, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-07-24, primaryCompletionDateStruct date: 2025-04-05, completionDateStruct date: 2025-06-01, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: Analysis of the collected data to determine:* Prevalence.* Risk factors. Radiological and clinical patterns and their association with specific risk factors Of Hallux Valgus, conditionsModule conditions: Hallux Valgus and Bunion, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 2000, type: ESTIMATED, armsInterventionsModule interventions name: epidemiology, outcomesModule primaryOutcomes measure: History taken and well clinical examination and AP Foot standing position of 2000 randomly case with determination of Hallux Valgus angles knowing if It's Hallux Valgus or not calculating The prevalence, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06335446, orgStudyIdInfo id: 011040- AT validation phase, secondaryIdInfos id: PG/16/10/32016, type: OTHER_GRANT, domain: British Heart Foundation, briefTitle: Identification, Electro-mechanical Characterisation and Ablation of Driver Regions in Persistent Atrial Fibrillation, statusModule overallStatus: COMPLETED, startDateStruct date: 2016-10, primaryCompletionDateStruct date: 2019-10, completionDateStruct date: 2019-10, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Barts & The London NHS Trust, class: OTHER, descriptionModule briefSummary: Atrial fibrillation (AF) is the most common sustained heart rhythm abnormality. Its incidence is increasing partly due to the aging population and it has been referred to as a growing epidemic. AF results in irregular contractions of the heart causing unpleasant symptoms of palpitations and increasing the risk of stroke, heart failure and death. Percutaneous catheter ablation is a safe treatment option in symptomatic patients with AF. The success rate of these procedures have improved with time due to our better understanding of AF, development of new techniques and technology, and greater physician experience. However, the success rate of these procedures still only remains around 70%. This is secondary to our limited ability to find the areas that drive AF.STAR mapping is a novel mapping system that has been developed with a view of better identifying the sites that drive AF through taking into account the mechanisms of AF we have so far demonstrated. To validate this mapping system we aim to use it in patients with atrial tachycardia (AT), which is a heart rhythm abnormality of which the mechanism can be readily identified with the existing mapping systems used in clinical practice. We will demonstrate that the STAR mapping algorithm can effectively map AT., conditionsModule conditions: Atrial Tachycardia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 30, type: ACTUAL, armsInterventionsModule interventions name: Novel mapping algorithm, outcomesModule primaryOutcomes measure: STAR maps compared to conventional maps, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Barts Heart Centre, city: London, zip: EC1A 7BE, country: United Kingdom, geoPoint lat: 51.50853, lon: -0.12574, hasResults: False
protocolSection identificationModule nctId: NCT06335420, orgStudyIdInfo id: 324-2023-GB, briefTitle: Prophylactic Properties of Carrot Juice in Patients With High-Risk Colorectal Polyps, acronym: Px7, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2026-04, completionDateStruct date: 2026-09, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Odense University Hospital, class: OTHER, collaborators name: Karolinska Institutet, collaborators name: Umeå University, collaborators name: Uppsala University Hospital, collaborators name: Sahlgrenska University Hospital, Sweden, collaborators name: Svendborg Hospital, descriptionModule briefSummary: The goal of this prospective randomized double-blinded bi-national study is to test the prophylactic effect of polyacetylenes from carrots on the population of patients who had a resection of high-risk adenomas of the large bowel.The main question it aims to answer is: Will carrot juice rich in polyacetylenes inhibit neoplastic transformation and growth in high-risk humans?Participants will have to drink 100 ml of juice daily after the adenoma resection for 1 year and keep a simple diary/calendar.Researchers will compare the group with ingestion of FaOH/FaDOH rich carrot juice versus the group consuming placebo juice, to see if the polyacetylenes significantly reduces neoplastic transformation and growth in high-risk patients., conditionsModule conditions: Colorectal Cancer Prevention, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 400, type: ESTIMATED, armsInterventionsModule interventions name: Carrot juice from Yellowstone carrots cultivars, interventions name: Placebo juice, outcomesModule primaryOutcomes measure: Number and size of polyps found at the one-year follow up colonoscopy, secondaryOutcomes measure: Polyp number and size in relation to carrot consumption measurement, secondaryOutcomes measure: Compliance rate (Juice consumption level), secondaryOutcomes measure: Side effects, secondaryOutcomes measure: Acceptability of treatment, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Department of Surgery, Odense University Hospital, city: Odense, zip: 5000, country: Denmark, geoPoint lat: 55.39594, lon: 10.38831, hasResults: False
protocolSection identificationModule nctId: NCT06335381, orgStudyIdInfo id: 24-0131, secondaryIdInfos id: 1R01NR021134-01, type: NIH, link: https://reporter.nih.gov/quickSearch/1R01NR021134-01, briefTitle: MOMs Chat and Care Study, acronym: MOMs-CC, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-15, primaryCompletionDateStruct date: 2027-12-31, completionDateStruct date: 2028-06-30, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-04-01, sponsorCollaboratorsModule leadSponsor name: Northwell Health, class: OTHER, collaborators name: National Institute of Nursing Research (NINR), descriptionModule briefSummary: The purpose of this pragmatic, randomized clinical trial designed to test the effectiveness of an integrated care model approach at two different levels of intensity designed to facilitate timely, appropriate care for high-risk Black birthing people and reduce risk for severe maternal morbidity (SMM). Eligible Black birthing people (n = 674) will be recruited and randomized to one of two study arms: MOMs High-Touch (MOMs-HT) vs. MOMs Low-Touch (MOMs-LT). The two study arms will be compared on incidence of SMM at labor and delivery (Aim 1), incidence rate of SMM-related hospitalizations at 1-month and 1-year postpartum (Aim 1a), time to preeclampsia diagnosis and initiation of treatment (Aim 2), change in perceived social support domains (Aim 3), and physical activity trajectories (exploratory Aim 4). Mixed methods will also be used to examine facilitators and barriers to implementation (Aim 5). Findings from this study will help to determine how to feasibly implement an effective and sustainable integrated care approach to address SMM disparities., conditionsModule conditions: Severe Maternal Morbidity, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Participants will be assigned to one of two groups in parallel for the duration of the study., primaryPurpose: PREVENTION, maskingInfo masking: SINGLE, maskingDescription: The Principal Investigator and Biostatistician will be masked., whoMasked: INVESTIGATOR, enrollmentInfo count: 674, type: ESTIMATED, armsInterventionsModule interventions name: Northwell Pregnancy & Peds Chats, interventions name: Prenatal Telehealth Visits, interventions name: Postpartum Telehealth Visits, interventions name: Home Blood Pressure Monitor, interventions name: Fitbit, outcomesModule primaryOutcomes measure: Severe maternal morbidity (SMM), secondaryOutcomes measure: Preeclampsia, secondaryOutcomes measure: Informational Support, secondaryOutcomes measure: Emotional Support, secondaryOutcomes measure: Tangible Support, otherOutcomes measure: Minutes of Physical Activity, otherOutcomes measure: Barriers to Exercise, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule locations facility: Northwell Health, city: Manhasset, state: New York, zip: 11030, country: United States, contacts name: Stephanie L Fitzpatrick, PhD, role: CONTACT, geoPoint lat: 40.79788, lon: -73.69957, hasResults: False
protocolSection identificationModule nctId: NCT06335368, orgStudyIdInfo id: 201512178RINC, briefTitle: Assessment of Nutritional and Growth Status in Rett Syndrome Patients, statusModule overallStatus: COMPLETED, startDateStruct date: 2016-03-09, primaryCompletionDateStruct date: 2016-05-23, completionDateStruct date: 2020-10-26, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: National Taiwan University Hospital, class: OTHER, descriptionModule briefSummary: Children with Rett syndrome are in a period of rapid growth, and proper and appropriate nutritional support is very important. Past foreign research papers it has been pointed out that most of these patients have feeding difficulties, dysphagia, and digestive tract abnormalities, are often constipated, and may suffer from osteoporosis and other problems. Lack of proper nutritional support will seriously affect their growth, development and health. in view of There is a lack of relevant research in China, so the investigators would like to use this research to explore the nutritional, growth and postural status of Rett's disease patients, as the reference direction and goal of dietary adjustment and nutritional support for patients, and establish dietary and nutritional strategies for sick children in Taiwan., conditionsModule conditions: Rett Syndrome, conditions: Neurologic Disorder, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: RETROSPECTIVE, enrollmentInfo count: 70, type: ACTUAL, armsInterventionsModule interventions name: Nutrition and Growth Status, outcomesModule primaryOutcomes measure: gender, age, disease history checklist, primaryOutcomes measure: Change in Body height, primaryOutcomes measure: Change in Body weight, primaryOutcomes measure: Change in knee height, primaryOutcomes measure: Change in arms height, primaryOutcomes measure: Change in waist, primaryOutcomes measure: Change in hip circumferences, eligibilityModule sex: ALL, minimumAge: 1 Year, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06335355, orgStudyIdInfo id: SHR-1316-307, briefTitle: A Phase II/III Study of Adebrelimab in Combination With SHR-8068 and Chemotherapy in Advanced or Metastatic NSCLC Patients, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2028-10, completionDateStruct date: 2030-10, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Shanghai Shengdi Pharmaceutical Co., Ltd, class: INDUSTRY, descriptionModule briefSummary: Evaluating the Efficacy and safety of Adebrelimab in Combination with Platinum-based Doublet Chemotherapy and SHR-8068 as First-line Therapy for Patients with Advanced or Metastatic NSCLC Carrying STK11/KEAP1/KRAS Mutations, conditionsModule conditions: Non-squamous Non-small Cell Lung Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE2, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 401, type: ESTIMATED, armsInterventionsModule interventions name: Adebrelimab + SHR-8068 + Pemetrexed + Carboplatin, interventions name: Camrelizumab + Pemetrexed + Carboplatin, interventions name: Adebrelimab + Pemetrexed + Carboplatin, outcomesModule primaryOutcomes measure: Investigator-assessed Objective Response Rate (Phase One), primaryOutcomes measure: Overall Survival (Phase Two), secondaryOutcomes measure: The incidence and severity of Adverse Events (AEs) (Phases One and Two), secondaryOutcomes measure: Duration of Response (DoR) based on Investigator Assessment (Phases One and Two), secondaryOutcomes measure: Disease Control Rate (DCR) based on Investigator Assessment (Phases One and Two), secondaryOutcomes measure: Progression-Free Survival (PFS) based on Investigator Assessment (Phases One and Two), secondaryOutcomes measure: Overall Survival (OS) (Phase One), secondaryOutcomes measure: Objective Response Rate (ORR) based on Investigator Assessment (Phase Two), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Affiliated Tumor Hospital of Shandong First Medical University, city: Jinan, state: Shandong, zip: 250117, country: China, contacts name: Jinming Yu, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 36.66833, lon: 116.99722, hasResults: False