protocolSection identificationModule nctId: NCT06338774, orgStudyIdInfo id: 202310129, secondaryIdInfos id: R33AG078041, type: NIH, link: https://reporter.nih.gov/quickSearch/R33AG078041, briefTitle: Cognitive Control to Boost Physical Activity Adherence, acronym: BOOST, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2027-05-01, completionDateStruct date: 2027-11-30, studyFirstPostDateStruct date: 2024-04-01, lastUpdatePostDateStruct date: 2024-04-02, sponsorCollaboratorsModule leadSponsor name: University of Iowa, class: OTHER, collaborators name: Northeastern University, collaborators name: National Institute on Aging (NIA), descriptionModule briefSummary: This trial is designed to develop and test the efficacy of cognitive training strategies to improve self-regulatory capacities for middle-aged adults to adopt and sustain a physically active lifestyle. The main questions it aims to answer are:* Can cognitive training designed to improve cognitive control improve physical activity adherence?* What are the psychological, physiological, cognitive, and sociodemographic factors that affect the impact of cognitive control on physical activity adherence?Participants will* Complete a 6-week home-based, computerized cognitive training program* Complete a 6-week home-based, aerobic exercise training program with supervision of a health coach and trainer* Complete a 6-week home-based, aerobic exercise training program prescribed by a health coach and trainer* Visit the laboratory before and after cognitive training, and before and after physical training, to complete assessments of cognition and aerobic fitness, conditionsModule conditions: Physical Inactivity, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Six week parallel group intervention, followed by a 12 week exercise program., primaryPurpose: BASIC_SCIENCE, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 264, type: ESTIMATED, armsInterventionsModule interventions name: Cognitive training, interventions name: Exercise, outcomesModule primaryOutcomes measure: Physical Activity Adherence, eligibilityModule sex: ALL, minimumAge: 40 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Psychological and Brain Sciences Building, city: Iowa City, state: Iowa, zip: 52242, country: United States, contacts name: Michelle W Voss, PhD, role: CONTACT, phone: 319-335-2057, email: michelle-voss@uiowa.edu, contacts name: Ruthina Malone, role: CONTACT, phone: 319-335-2407, email: ruthina-malone@uiowa.edu, contacts name: Michelle Voss, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 41.66113, lon: -91.53017, locations facility: Center for Cognitive and Brain Health, city: Boston, state: Massachusetts, zip: 02115, country: United States, contacts name: Charles Hillman, PhD, role: CONTACT, phone: 617-373-8342, email: c.hillman@northeastern.edu, contacts name: Virginia Davis, role: CONTACT, phone: 617-373-3448, email: vi.davis@northeastern.edu, contacts name: Charles Hillman, PhD, role: PRINCIPAL_INVESTIGATOR, contacts name: Arthur F Kramer, PhD, role: SUB_INVESTIGATOR, geoPoint lat: 42.35843, lon: -71.05977, hasResults: False