hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06344650, orgStudyIdInfo id: RF-2021-12373584, briefTitle: Cellular, Molecular and Clinical Determinants of Bone Strength in in Vivo and Human Models of GH Excess. Cross-sectional and Prospective Study, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-09-28, primaryCompletionDateStruct date: 2024-07, completionDateStruct date: 2024-07, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: IRCCS San Raffaele, class: OTHER, collaborators name: Fondazione Policlinico Universitario Campus Bio-Medico, collaborators name: Istituto Auxologico Italiano, descriptionModule briefSummary: Prospective observational clinical, molecular, translational and basic study aimed at identifying the main determinants and predictive factors of risk of bone damage in acromegaly patients, conditionsModule conditions: Acromegaly, conditions: Bone Fracture, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CROSSOVER, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Blood sample, outcomesModule primaryOutcomes measure: Identify the rate of morphometric vertebral fractures in acromegalic patients, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Andrea Giustina, status: RECRUITING, city: Milan, zip: 20132, country: Italy, contacts name: Gabriela Felipe, role: CONTACT, phone: 0226435062, email: felipe.gabriela@hsr.it, geoPoint lat: 45.46427, lon: 9.18951, hasResults: False
protocolSection identificationModule nctId: NCT06344637, orgStudyIdInfo id: 2566/081 I, briefTitle: Effects of Cervical Lidocaine Spray on Pain Relief During Manual Vacuum Aspiration, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-12-14, primaryCompletionDateStruct date: 2024-05-30, completionDateStruct date: 2024-07-30, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: UdonThani Hospital, class: OTHER_GOV, descriptionModule briefSummary: This randomized control trial aim to evaluate the effectiveness of local lidocaine spray application to the cervix on the reducing of pain score during the manual vacuum aspiration, conditionsModule conditions: Pain, Procedural, conditions: Lidocaine, conditions: Obstetric Surgical Procedures, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, enrollmentInfo count: 216, type: ACTUAL, armsInterventionsModule interventions name: 10 % lidocaine spray without adrenaline, interventions name: Placebo, outcomesModule primaryOutcomes measure: pain score during manual vauum aspiration, primaryOutcomes measure: pain score after manual vauum aspiration, eligibilityModule sex: FEMALE, minimumAge: 20 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: UdonThani Hospital, city: Udon Thani, state: UdonThani, zip: 41000, country: Thailand, geoPoint lat: 17.41567, lon: 102.78589, documentSection largeDocumentModule largeDocs typeAbbrev: Prot_SAP, hasProtocol: True, hasSap: True, hasIcf: False, label: Study Protocol and Statistical Analysis Plan, date: 2023-10-30, uploadDate: 2024-03-20T05:36, filename: Prot_SAP_000.pdf, size: 178265, hasResults: False
protocolSection identificationModule nctId: NCT06344624, orgStudyIdInfo id: Mersin_U, briefTitle: The Effect of Cognitive and Laughter Therapy on Psychological Symptoms in Nursing Students, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-10, primaryCompletionDateStruct date: 2024-06-02, completionDateStruct date: 2025-02-01, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Mersin University, class: OTHER, descriptionModule briefSummary: The presence of high mental symptoms among nursing students in Turkey highlights the need to develop various support strategies in nursing education to preserve and ensure the continuity of the nursing workforce. This study aims to compare the effects of brief cognitive-behavioral group psychotherapy and laughter yoga on mental symptoms in nursing students with mental symptoms., conditionsModule conditions: Mental Health Issue, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: A randomized controlled trial with a pretest-posttest design, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: DOUBLE, maskingDescription: Using the block randomization technique, the sampled students will be split into two groups: the CBT group and the laughter group. Six will be the block size. Excel will be used to create blocks (allocation concealment) and random numbers will be generated by an assistant researcher who does not attend therapy sessions. The purpose of the program is to support mental health and evaluate its effectiveness; students will not be informed about which group they are in (participant blinding).Research data will be coded as A and B and entered into the computer database by someone other than the researchers conducting the therapy sessions, and statistical analysis will be performed using this coding (statistician blinding)., whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 114, type: ESTIMATED, armsInterventionsModule interventions name: CBT group, interventions name: Laughter group, outcomesModule primaryOutcomes measure: The change in mental symptoms will be assessed using the Brief Symptom Inventory., secondaryOutcomes measure: Psychological resilience will be assessed using the Psychological Resilience Scale., secondaryOutcomes measure: Negative self-evaluations and thought patterns will be assessed using the Automatic Thoughts Scale., eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule locations facility: Turkey, Mersin University, city: Mersin, zip: 33180, country: Turkey, contacts name: EMİNE ÖNCÜ, Assoc.Prof., role: CONTACT, email: eeoncu@gmail.com, contacts name: Zeliha Yaman, Doctorate, role: SUB_INVESTIGATOR, contacts name: Filiz Değirmenci, Doctorate, role: SUB_INVESTIGATOR, geoPoint lat: 36.79526, lon: 34.61792, hasResults: False
protocolSection identificationModule nctId: NCT06344611, orgStudyIdInfo id: ILBS-DCLD-01, briefTitle: Incidence & Predictive Factors of Recompensation in Children With Decompensated Cirrhosis as Per the Baveno VII Criteria, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-07, primaryCompletionDateStruct date: 2026-03-31, completionDateStruct date: 2026-03-31, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Institute of Liver and Biliary Sciences, India, class: OTHER, descriptionModule briefSummary: Cirrhosis is a leading cause of morbidity and mortality world- wide and can develop on the basis of repetitive and/or chronic liver injury due to toxic, infectious, metabolic and genetic pathogenic factors. Traditionally, the natural history of cirrhosis has often been considered a one-way street, with a definite and irreversible progression from a compensated to a decompensated disease stage. But recent data has shown that if the underlying etiology can be successfully treated, cirrhosis can regress and recompensation of liver disease can occur. Hence, in this study we want to evaluate the incidence and predictive factors of recompensation in pediatric subjects with decompensated cirrhosis as per the Baveno VII criteria. We would also evaluate the predictive factors of recompensation in pediatric decompensated chronic liver disase (DCLD) subjects and would explore systemic and intestinal inflammatory markers as possible biomarkers for predicting recompensation in pediatric subjects with decompensated cirrhosis., conditionsModule conditions: Decompensated Cirrhosis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Other, outcomesModule primaryOutcomes measure: To determine the incidence of recompensation in pediatric subjects with decompensated cirrhosis as per Baveno VII criteria, secondaryOutcomes measure: To evaluate the predictive factors of recompensation in pediatric DCLD subjects, secondaryOutcomes measure: To investigate the systemic and intestinal inflammatory markers as possible biomarkers for predicting recompensation in in pediatric subjects with decompensated cirrhosis., secondaryOutcomes measure: To assess incidence of re-decompensation in patients with recompensation., eligibilityModule sex: ALL, minimumAge: 3 Months, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Institute of Liver and Biliary Sciences, city: New Delhi, state: Delhi, zip: 110070, country: India, contacts name: Dr Anmol Anmol, MD, role: CONTACT, phone: 01146300000, email: dranmol1991@gmail.com, geoPoint lat: 28.63576, lon: 77.22445, hasResults: False
protocolSection identificationModule nctId: NCT06344598, orgStudyIdInfo id: 0123РК00314, secondaryIdInfos id: AP19680262, type: OTHER, domain: Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan, briefTitle: Identification and Assessment of Risk Factors for the Development of Osteoporosis in Adults and Children Living in the Abay Region of the Republic of Kazakhstan Using the Method of Dual-energy X-ray Absorptiometry and Clinical and Epidemiological Research, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-09-01, primaryCompletionDateStruct date: 2025-11-15, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Semey State Medical University, class: OTHER, collaborators name: Ministry of Science and Higher Education of the Republic of Kazakhstan, descriptionModule briefSummary: A survey of people to identify risk factors for osteoporosis, which include age, gender, lifestyle, diet, physical activity, the presence or absence of somatic pathology. Diagnosis of osteoporosis by dual-energy X-ray absorptiometry. Conducting a correlation analysis of the relationship of the data obtained., conditionsModule conditions: Improving the Early Diagnosis of Osteoporosis in Adults and Children Living in the Abay Region of Kazakhstan, designModule studyType: OBSERVATIONAL, designInfo observationalModel: ECOLOGIC_OR_COMMUNITY, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 1000, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Risk factors for the development of osteoporosis will be identified and quantified in the formed study groups of adults, primaryOutcomes measure: to determine the diagnostic value of the risk factors for the development of osteoporosis obtained during the examination, primaryOutcomes measure: to assess the state of BMD in adults using X-ray absorptiometry (DXA), primaryOutcomes measure: To carry out a correlation analysis of the relationship between the obtained data in adults of the Abay region of of the Republic of Kazakhstan, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Semey Medical University, status: RECRUITING, city: Semey, zip: 071400, country: Kazakhstan, contacts name: Madina MD Madiyeva, PhD, role: CONTACT, phone: +77085244745, email: madina.madiyeva@smu.edu.kz, contacts name: Gulzhan MD Bersimbekova, role: CONTACT, phone: +77023728412, email: gulzhan.bersimbekova@smu.edu.kz, geoPoint lat: 50.42675, lon: 80.26669, hasResults: False
protocolSection identificationModule nctId: NCT06344585, orgStudyIdInfo id: DROPOUT, briefTitle: Drop-out of Infertile Couples: a Large Single Center Experience Over 10 Years, acronym: dropout, statusModule overallStatus: COMPLETED, startDateStruct date: 2012-01-01, primaryCompletionDateStruct date: 2021-12-31, completionDateStruct date: 2023-07-31, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Istituto Clinico Humanitas, class: OTHER, descriptionModule briefSummary: Conducted at a single-center, this prospective-retrospective study focused on all couples who initiated their journey at the Fertility Center of Humanitas Research Hospital, Rozzano (Milan), Italy.The prospective study focused on the couples whose first consultation occurred in 2021. A tailored questionnaire was administered via telephone by staff members to gather insights into the personal reasons for treatment discontinuation among non-returning patients.Conversely, the retrospective study included all infertile couples initiating treatment between January 2012 and December 2021 at the Fertility Center. Data encompassing personal history and demographic details were extracted from the internal database of Humanitas Fertility Center to assess the factors involved in a treatment discontinuation., conditionsModule conditions: Infertility, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: RETROSPECTIVE, enrollmentInfo count: 24773, type: ACTUAL, armsInterventionsModule interventions name: Drop out patients who had their first access in 2021 were additionally asked to answer to a phone -call questionnaire to assess their motivation of discontinuation, outcomesModule primaryOutcomes measure: Dropout rate, secondaryOutcomes measure: Reasons for dropout collected by a phone call questionnaire, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 46 Years, stdAges: ADULT, contactsLocationsModule locations facility: Istituto Clinico Humanitas, city: Rozzano, state: Milano, zip: 20089, country: Italy, geoPoint lat: 45.38193, lon: 9.1559, hasResults: False
protocolSection identificationModule nctId: NCT06344572, orgStudyIdInfo id: SAT001-KP-002, briefTitle: Pivotal Study of SAT-001 in Treatment of Pediatric Patient With Myopia, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-09-27, primaryCompletionDateStruct date: 2025-08-31, completionDateStruct date: 2025-09-30, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: S-Alpha Therapeutics, Inc., class: INDUSTRY, descriptionModule briefSummary: The objective of this clinical investigation is to evaluate the efficacy and safety of SAT-001 designed as Software as Medical Device (SaMD) for slowing myopia progression and treatment in pediatric myopia patients., conditionsModule conditions: Myopia, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 110, type: ESTIMATED, armsInterventionsModule interventions name: SAT-001, interventions name: Single vision spectacles, outcomesModule primaryOutcomes measure: Change in Cycloplegic Spherical Equivalent Refractive Error, secondaryOutcomes measure: Change in Cycloplegic Spherical Equivalent Refractive Error, secondaryOutcomes measure: Change in Axial Length, secondaryOutcomes measure: Change in cycloplegic Spherical Equivalent Refractive Error relative to baseline depending on the myopia severity(mild myopia, moderate myopia), secondaryOutcomes measure: Change in axial length relative to baseline depending on the myopia severity(mild myopia, moderate myopia), eligibilityModule sex: ALL, minimumAge: 5 Years, maximumAge: 8 Years, stdAges: CHILD, contactsLocationsModule locations facility: Gachon University Gil Hospital, status: RECRUITING, city: Incheon, country: Korea, Republic of, geoPoint lat: 37.45646, lon: 126.70515, hasResults: False
protocolSection identificationModule nctId: NCT06344546, orgStudyIdInfo id: K 2023-10247, briefTitle: Metabolic Pathway Analysis in Intensive Care Unit Patients With Refeeding Syndrome, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2024-06, completionDateStruct date: 2024-06, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Karolinska University Hospital, class: OTHER, descriptionModule briefSummary: The overall aim of the study is to improve understanding of refeeding syndrome (RFS) in patients admitted to the intensive care unit (ICU) using metabolomics. Patients are included as part of a prospective multicenter observational study on phosphate disorders in the ICU. Blood samples are collected day 1-7 of ICU stay. Samples from patients who develop refeeding hypophosphatemia and matched controls without hypophosphatemia are analysed for metabolomics and proteomics. Untargeted analyses will be performed to identify the affected metabolic pathways. The investigators will also perform AUROC analyses to identify potential biomarkers for early detection of RFS., conditionsModule conditions: Critical Illness, conditions: Refeeding Syndrome, conditions: Hypophosphatemia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 500, type: ESTIMATED, armsInterventionsModule interventions name: Metabolomics, outcomesModule primaryOutcomes measure: Metabolomics, secondaryOutcomes measure: Metabolomics, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University Hospital Královské Vinohrady, city: Prague, country: Czechia, geoPoint lat: 50.08804, lon: 14.42076, locations facility: University Hospital Policlinico of Foggia, city: Foggia, country: Italy, geoPoint lat: 41.45845, lon: 15.55188, locations facility: Karolinska University Hospital, city: Huddinge, state: Stockholm, zip: 14186, country: Sweden, contacts name: Martin Sundström Rehal, MD PhD, role: CONTACT, phone: +46-8-12381507, email: martin.sundstrom@gmail.com, contacts name: Olav Rooyackers, PhD, role: CONTACT, email: olav.rooyackers@ki.se, geoPoint lat: 59.23705, lon: 17.98192, locations facility: Karolinska Universitetssjukhuset Solna, city: Stockholm, country: Sweden, contacts name: Jonas Blixt, MD PhD, role: CONTACT, email: jonas.blixt@regionstockholm.se, geoPoint lat: 59.33258, lon: 18.0649, locations facility: Södersjukhuset, city: Stockholm, country: Sweden, contacts name: Rebecka Rubenson Wahlin, MD PhD, role: CONTACT, email: rebecka.rubenson-wahlin@regionstockholm.se, geoPoint lat: 59.33258, lon: 18.0649, hasResults: False
protocolSection identificationModule nctId: NCT06344533, orgStudyIdInfo id: JMKX003142iv-101, briefTitle: Study of JMKX003142 Injection in Chinese Healthy Subjects, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-10, primaryCompletionDateStruct date: 2025-01-31, completionDateStruct date: 2025-05-30, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Jemincare, class: INDUSTRY, collaborators name: Zhejiang Hangyu Pharmaceutical Co., Ltd, descriptionModule briefSummary: To Evaluate the Safety, Tolerability, and Pharmacokinetic Characteristics of JMKX003142 Injection Administered Randomly, Double-blind, Placebo-controlled, Single-ascending Dose and Multiple-ascending Doses in Chinese Healthy Adult Subjects, conditionsModule conditions: Healthy Adult, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 78, type: ESTIMATED, armsInterventionsModule interventions name: JMKX003142 Injection, interventions name: Placebo, outcomesModule primaryOutcomes measure: Number of the Adverse Events that are related to the single dose treatment, primaryOutcomes measure: Number of the Adverse Events that are related to the multiple dose treatment, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule locations facility: Peking University Third Hospital, city: Beijing, state: Beijing, zip: 100191, country: China, contacts name: Haiyan Li, role: CONTACT, contacts name: Haiyan Li, MD, role: PRINCIPAL_INVESTIGATOR, contacts name: Dongyang Liu, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 39.9075, lon: 116.39723, hasResults: False
protocolSection identificationModule nctId: NCT06344520, orgStudyIdInfo id: IsiU, briefTitle: Pectoralis Minor Shorthening and Swimming Performance, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-12-29, primaryCompletionDateStruct date: 2023-08-30, completionDateStruct date: 2023-10-30, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Istinye University, class: OTHER, descriptionModule briefSummary: Swimming is one of the sports branches that includes many factors such as aerobic and anaerobic endurance, strength, flexibility, speed, quickness, rhythm, coordination as well as sportive performance and technical skills.Athletes must have a high level of fitness, strength, coordination, agility, speed and motor control to perform at an elite level with minimal injury risk.Repetitive upper extremity movements imposed by freestyle swimming may lead to changes in muscle length and tension by paving the way for postural misalignment in adolescent swimmers.As can be seen in the studies, young swimmers who are preparing for the competition have postural disorders and injuries related to use, such as decreased posture, shoulder joint range of motion and subacromial distance.Pectoralis minor stretching exercise to be performed in swimmers is aimed to improve swimming performance and prevent possible postural disorders by contributing to the increase of maximal shoulder muscle strength as well as correcting the incorrectly developed posture in children., conditionsModule conditions: The Study Will Not be Based on Any Disease, conditions: Ability to Swim 100m Independent Freestyle, conditions: Be Between the Ages of 9-16, conditions: Continuing Running as Part of a Sports Club, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: three groups as intervention, exercises group non- exercises group and scham, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: NONE, enrollmentInfo count: 91, type: ACTUAL, armsInterventionsModule interventions name: pektoralis minor shortnes, interventions name: Group in which the Pectoralis Minor stretching exercise was performed in a sham manner, interventions name: The group in which Pectoralis Minor stretching exercise was not applied, outcomesModule primaryOutcomes measure: Speed Tests, primaryOutcomes measure: Apley test, primaryOutcomes measure: Round Shoulder, primaryOutcomes measure: Anthropometric Measurement:, primaryOutcomes measure: Posture analysis: (ANNEX2), primaryOutcomes measure: Anthropometric Measurement 2, primaryOutcomes measure: Y Balance Test, primaryOutcomes measure: Eurofit Test Battery, primaryOutcomes measure: Eurofit Test Battery 2, primaryOutcomes measure: Eurofit Test Battery 3, eligibilityModule sex: ALL, minimumAge: 9 Years, maximumAge: 16 Years, stdAges: CHILD, contactsLocationsModule locations facility: Galatasaray Ergün Gürsoy Olympic Swimming Pool, city: Üsküdar, state: Nuhkuyusu, zip: 34662, country: Turkey, geoPoint lat: 41.02252, lon: 29.02369, hasResults: False