hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06378957, orgStudyIdInfo id: IRB00436545, briefTitle: Behavioral Pharmacology of Orally Administered THC and D-limonene, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09-01, primaryCompletionDateStruct date: 2027-07-01, completionDateStruct date: 2027-12-31, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Johns Hopkins University, class: OTHER, collaborators name: National Institutes of Health (NIH), descriptionModule briefSummary: The current clinical trial will investigate the effects of orally administered d-limonene (limonene), delta-9-tetrahydrocannabinol (THC) and the combination in healthy adult volunteers., conditionsModule conditions: Subjective Drug Effects, conditions: THC, conditions: D-limonene, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: Within-subjects design where participants are randomly assigned to dose conditions, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: DOUBLE, maskingDescription: place controlled, double-blind, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 65, type: ESTIMATED, armsInterventionsModule interventions name: D-Limonene, interventions name: Delta-9-THC, interventions name: Placebo, outcomesModule primaryOutcomes measure: Subjective Drug Effect as assessed by Visual Analog Scale, secondaryOutcomes measure: Subjective Drug Liking as assessed by Visual Analog Scale, secondaryOutcomes measure: Subjective anxiety as assessed by Visual Analog Scale, secondaryOutcomes measure: Subjective hunger as assessed by Visual Analog Scale, secondaryOutcomes measure: Subjective paranoia as assessed by Visual Analog Scale, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule locations facility: Johns Hopkins Behavioral Pharmacology Research Unit, city: Baltimore, state: Maryland, zip: 21224, country: United States, geoPoint lat: 39.29038, lon: -76.61219, hasResults: False
protocolSection identificationModule nctId: NCT06378944, orgStudyIdInfo id: 61/23, briefTitle: Selective Sentinella Lymph Node Biopsy With Indocyanine Green in Patients With Breast Cancer, acronym: INSEAN, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2029-01-01, completionDateStruct date: 2029-01-01, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Omphis Foundation, class: OTHER, descriptionModule briefSummary: The current observational study aims to perform the sentinel lymph node in breast cancer in the usual way with technetium 99 and add a second tracer, indocyanine green. The objective is to evaluate the detection rate of the lymph node with indocyanine green compared to the usual technique., conditionsModule conditions: Breast Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 15000, type: ESTIMATED, armsInterventionsModule interventions name: Application of green indocyanine colorant, interventions name: Technetium99, outcomesModule primaryOutcomes measure: Number of Sentinel lymph node detected. Scale of numbers, secondaryOutcomes measure: Number of possitive lymph nodes, secondaryOutcomes measure: surgery time in minutes, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 120 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Sandra Lopez Gordo, status: RECRUITING, city: Cerdanyola Del Valles, state: Barcelona, zip: 08290, country: Spain, contacts name: Sandra Lopez gordo, role: CONTACT, phone: 660284047, email: sandra.lopezgordo@gmail.com, geoPoint lat: 41.49109, lon: 2.14079, hasResults: False
protocolSection identificationModule nctId: NCT06378931, orgStudyIdInfo id: 2024HX161, briefTitle: Quality of Life Change in Patients Undergoing Parathyroidectomy With End-stage Renal Failure, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-15, primaryCompletionDateStruct date: 2025-12-30, completionDateStruct date: 2025-12-30, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Chunling Jiang, class: OTHER, descriptionModule briefSummary: The purpose of this study is to characterize the quality of life change in patients undergoing parathyroidectomy with secondary hyperparathyroidism due to end-stage renal failure., conditionsModule conditions: Secondary Hyperparathyroidism, conditions: End Stage Renal Failure, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Quality of life progression after parathyroidectomy, outcomesModule primaryOutcomes measure: Measure quality of life scores change with respect to time, secondaryOutcomes measure: Measure anxiety and depression score change with respect to time, secondaryOutcomes measure: Measure bone pain scores change with respect to time, secondaryOutcomes measure: Length of hospital stay, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06378918, orgStudyIdInfo id: 2023-A02791-44, briefTitle: Comparison of the Effectiveness of the Simple Puncture Compared to the Incision of an Abscess on the piLOnidal Sinus, acronym: PILO, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-15, primaryCompletionDateStruct date: 2025-04-15, completionDateStruct date: 2027-04-15, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: University Hospital, Angers, class: OTHER_GOV, descriptionModule briefSummary: Pilonidal disease is a common disease characterized by the presence of abscess in the intergluteal groove. During periods of abscess, current recommendations are to make a simple incision with daily wicking of the abscess. Direct excision at this time is not recommended because there is a risk of incomplete excision. The principle of directed healing after incision of the abscess results in an average dressing period of 21 days. A definitive resection is recommended after 4 to 6 weeks, when healing has been achieved, in order to limit the risk of infectious recurrence.An alternative has recently been proposed, consisting of a puncture of the abscess, aimed at emptying it under antibiotic coverage. The major advantage of this treatment is that patients no longer need general anesthesia to flatten the abscess. Although this technique is promising, it is currently not the subject of any published or ongoing randomized controlled study registered on Clinicaltrials.gov.The research hypothesis is that the two techniques have the same results in terms of recurrence before definitive surgical treatment but that drainage puncture would imply a faster healing time, a lower cost of treatment, a quality of superior support, reduced support time and reduced work stoppage., conditionsModule conditions: Pilonidal Cyst, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 134, type: ESTIMATED, armsInterventionsModule interventions name: puncture, interventions name: incision of the abscess, outcomesModule primaryOutcomes measure: healing time, secondaryOutcomes measure: Effectiveness of the 2 procedures, secondaryOutcomes measure: Cost-utility analysis, secondaryOutcomes measure: Duration of nursing care, secondaryOutcomes measure: Duration of work stoppage, secondaryOutcomes measure: Returning to work, secondaryOutcomes measure: Quality of life, secondaryOutcomes measure: Healing after definitive resection, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06378879, orgStudyIdInfo id: 1073/1/3/26, briefTitle: Intermittent Boluses Versus Infusion of Propofol During Gastroscopy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-06, primaryCompletionDateStruct date: 2025-04-30, completionDateStruct date: 2025-07-30, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Al-Balqa Applied University, class: OTHER, collaborators name: Luzmila Hospital, descriptionModule briefSummary: It is unclear whether continuous infusion or intermittent bolus injection of propofol is better for achieving adequate sedation during a standard upper endoscopy. The study aimed to compare the efficacy and safety of continuous infusion and intermittent bolus injection of Propofol (Diprivan) during a standard upper endoscopy. In this prospective study, patients will be randomly assigned to undergo a standard upper endoscopy with either continuous infusion (CI group) or intermittent bolus injection (BI group) of Propofol (Diprivan) administered by an anesthesiologist. The primary outcome will be to assess the quality of sedation by the endoscopist (VAS). In addition to other sedation-related parameters that will include sedation induction time (minutes), total dose of propofol (mg), recovery time (minutes) using Aldrete score, any involuntary patient movement, and adverse events., conditionsModule conditions: Anesthesia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Propofol 100 MG in 10 ML Injection, outcomesModule primaryOutcomes measure: Sedation induction time (minutes), primaryOutcomes measure: Total dose of propofol (mg), primaryOutcomes measure: Recovery time (minutes), secondaryOutcomes measure: Involuntary movement, secondaryOutcomes measure: Quality of sedation, secondaryOutcomes measure: Adverse events, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 85 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06378853, orgStudyIdInfo id: 2023DZKY-049-01, briefTitle: Risk Factors of Postoperative Complications and Survival Rate in Pancreatic Ductal Adenocarcinoma Patients, statusModule overallStatus: COMPLETED, startDateStruct date: 2019-01-01, primaryCompletionDateStruct date: 2023-12-31, completionDateStruct date: 2024-02-28, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Jinling Hospital, China, class: OTHER, descriptionModule briefSummary: By evaluating the nutritional status of patients with pancreatic ductal adenocarcinoma (PDAC) admitted to Jinling Hospital, collecting relevant clinical data. we aim to conduct correlation analysis with patient clinical information, such as survival time, hospitalization time, nutritional status, hematological indicators, etc., in order to reveal the prognostic factors for overall survival and postoperative complications of PDAC patients., conditionsModule conditions: Pancreatic Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 548, type: ACTUAL, armsInterventionsModule interventions name: no intervention, outcomesModule primaryOutcomes measure: complications, primaryOutcomes measure: overall survival, primaryOutcomes measure: risk factors, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Jinling Hospital, city: Nanjing, country: China, geoPoint lat: 32.06167, lon: 118.77778, hasResults: False
protocolSection identificationModule nctId: NCT06378840, orgStudyIdInfo id: KY2021-268-B, briefTitle: the Predictive Value of Immune Cell in Locally Advanced Cervical Cancer, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-01-01, primaryCompletionDateStruct date: 2024-12-30, completionDateStruct date: 2024-12-30, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: RenJi Hospital, class: OTHER, descriptionModule briefSummary: To explore the predictive value of immune cells by single-cell sequencing on the outcome of locally advanced cervical cancer treated by concurrent chemoradiotherapy Followed by PD-1 inhibitor, conditionsModule conditions: Locally Advanced Cervical Carcinoma, conditions: Concurrent Chemoradiotherapy, conditions: Immunotherapy, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: Nab-paclitaxel/Platinum, Sintilimab, outcomesModule primaryOutcomes measure: the change of immune cells in the blood after chemoradiotherapy and immunotherapy, primaryOutcomes measure: the predictive value of the changed immune cell subtype in the blood on the side effect of immunotherapy, primaryOutcomes measure: the predictive value of the changed immune cell subtype in the blood on the effect of chemoradiotherapy and immunotherapy, secondaryOutcomes measure: the change of immune cells in the tissue after chemoradiotherapy, secondaryOutcomes measure: the predictive value of the changed immune cell subtype in the tissue on the effect of chemoradiotherapy and immunotherapy, secondaryOutcomes measure: the predictive value of the changed immune cell subtype in the tumor microenvironment on the side effect of immunotherapy, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: RenJi hospital, status: RECRUITING, city: Shanghai, zip: 200127, country: China, contacts name: Haiyan Chen, Dr, role: CONTACT, phone: +862168383624, email: chenhaiyan@renji.com, geoPoint lat: 31.22222, lon: 121.45806, hasResults: False
protocolSection identificationModule nctId: NCT06378827, orgStudyIdInfo id: 418-1/2, briefTitle: Intraoperative Dexmedetomidine and Coronary Artery Bypass Graft Surgery, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-03, primaryCompletionDateStruct date: 2024-07, completionDateStruct date: 2024-10, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: University of Novi Sad, class: OTHER, descriptionModule briefSummary: This is a prospective randomized clinical trial designed to determine the effect of intraoperative dexmedetomidine administration on renal function after coronary artery bypass graft surgery., conditionsModule conditions: Acute Kidney Injury, designModule studyType: INTERVENTIONAL, phases: PHASE2, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Dexmedetomidine, outcomesModule primaryOutcomes measure: Indicator of renal function, primaryOutcomes measure: An early biomarker of kidney injury, primaryOutcomes measure: The change of inflammatory markers, secondaryOutcomes measure: Length of postoperative mechanical ventilation, secondaryOutcomes measure: Length of stay in the intensive care unit, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Novi Sad, Faculty of Medicine, status: RECRUITING, city: Novi Sad, zip: 21000, country: Serbia, contacts name: Ranko Zdravkovic, role: CONTACT, phone: +381654674620, email: ranko.zdravkovic@mf.uns.ac.rs, geoPoint lat: 45.25167, lon: 19.83694, hasResults: False
protocolSection identificationModule nctId: NCT06378801, orgStudyIdInfo id: RADX-P-2408, briefTitle: Radicle Relaxation 24: A Study of Health and Wellness Products on Stress and Related Health Outcomes, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-02-29, primaryCompletionDateStruct date: 2024-05, completionDateStruct date: 2024-08, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Radicle Science, class: INDUSTRY, descriptionModule briefSummary: A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on stress and related health outcomes, conditionsModule conditions: Stress, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Participants will be stratified based on gender at birth, then randomized to one of the study arms, primaryPurpose: OTHER, maskingInfo masking: DOUBLE, maskingDescription: The investigator is blinded to the participants' study product assignment. Participants are blinded to the study product they are assigned., whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 500, type: ACTUAL, armsInterventionsModule interventions name: Placebo Control Form 1, interventions name: Relaxation Active Study Product 1.1, outcomesModule primaryOutcomes measure: Change in stress, secondaryOutcomes measure: Change in feelings of anxiety, secondaryOutcomes measure: Change in cognitive function, secondaryOutcomes measure: Change in mood (emotional distress-depression), secondaryOutcomes measure: Minimal clinically important difference (MCID) in stress, secondaryOutcomes measure: Minimal clinically important difference (MCID) in feelings of anxiety, secondaryOutcomes measure: Minimal clinically important difference (MCID) in cognitive function, secondaryOutcomes measure: Minimal clinically important difference (MCID) in mood (emotional distress-depression), otherOutcomes measure: Change in concentration of at-home (direct-to-consumer) specimen assays either saliva, blood or stool, eligibilityModule sex: ALL, minimumAge: 21 Years, maximumAge: 105 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Radicle Science, Inc, city: Del Mar, state: California, zip: 92014, country: United States, geoPoint lat: 32.95949, lon: -117.26531, hasResults: False
protocolSection identificationModule nctId: NCT06378775, orgStudyIdInfo id: H23-03334, briefTitle: Robotically-assisted Minimally-invasive Direct Coronary Artery Bypass With Stenting, Randomized Against Coronary Artery Bypass Graft Surgery, acronym: ROBOT RCT, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2027-05-01, completionDateStruct date: 2028-12-01, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Cardiology Research UBC, class: OTHER, descriptionModule briefSummary: The study objective is to compare standard CABG to a hybrid revascularization strategy (RA-MIDCAB + PCI) in patients who have multi-vessel CAD and an indication for surgery, but who have a slightly higher risk of post-operative complications., conditionsModule conditions: Coronary Artery Disease, conditions: Multivessel Coronary Artery Disease, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Coronary Artery Bypass Graft, interventions name: Robotically-assisted minimally-invasive direct coronary artery bypass, interventions name: Percutaneous Coronary Intervention, outcomesModule primaryOutcomes measure: Post-operative Length of Stay, secondaryOutcomes measure: Conversion to sternotomy / CABG, otherOutcomes measure: Intubation duration, otherOutcomes measure: ICU length of stay, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06378762, orgStudyIdInfo id: 6/2021, briefTitle: Interference of Endurance Training on Strength Development and Neuromuscular Adaptations, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2022-04-01, primaryCompletionDateStruct date: 2024-07-30, completionDateStruct date: 2025-07-30, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: University of Lisbon, class: OTHER, collaborators name: Fundação para a Ciência e a Tecnologia, descriptionModule briefSummary: This study aims to find out if performing combined strength and endurance exercise in the same program (called concurrent training-CT) leads to similar long-term improvements in neuromuscular function as doing each type of exercise separately. The main questions it seeks to answer are:Does performing CT result in similar improvements in strength and power as doing just strength training? Does performing CT result in similar improvements in cardiorespiratory fitness as doing just endurance training? Are neuromuscular adaptations similar between CT and just strength training? Researchers will compare the results between three groups: the CT group, the endurance training group (E), and the strength training group (S) to answer these questions., conditionsModule conditions: Exercise, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ACTUAL, armsInterventionsModule interventions name: Endurance Exercise, interventions name: Strength Exercise, interventions name: Concurrent Exercise, outcomesModule primaryOutcomes measure: Maximal Isometric Strength, primaryOutcomes measure: Maximal Dynamic Strength, primaryOutcomes measure: Surface EMG, primaryOutcomes measure: H-reflex excitability, primaryOutcomes measure: V-wave, primaryOutcomes measure: Lower Body Muscle Power, primaryOutcomes measure: Muscle architecture of the quadriceps femoris, eligibilityModule sex: MALE, minimumAge: 18 Years, maximumAge: 30 Years, stdAges: ADULT, contactsLocationsModule locations facility: Faculdade de Motricidade Humana - Universidade de Lisboa, city: Lisboa, state: Cruz Quebrada - Dafundo, zip: 1499-002, country: Portugal, geoPoint lat: 38.71667, lon: -9.13333, hasResults: False