hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06301347, orgStudyIdInfo id: LTP+P, briefTitle: Learning Through Play Plus for Psychosis, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-04-30, completionDateStruct date: 2025-12-30, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Pakistan Institute of Living and Learning, class: OTHER, descriptionModule briefSummary: Evidence reports that parents with schizophrenia are particularly vulnerable to parenting difficulties and also experience problems in sensitively interacting with their children. This may cause insecure attachment in infants of mothers with psychosis. Children of parents with schizophrenia have poor developmental and clinical outcomes. However, there is no published trial, to the best of our knowledge, for children of parents with schizophrenia. Learning through Play (LTP) is a potentially low cost intervention to improve maternal mental health and child outcomes by promoting health child development. The proposed study will integrate LTP with existing culturally appropriate Cognitive Behaviour Theray (CBT) for psychosis (CaCBT-p) and test its feasibility and acceptability for parents with schizophrenia., conditionsModule conditions: Psychosis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Participants will be randomized into one of the two treatment conditions (LTP Plus or TAU) through computer generated algorithm., primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 90, type: ESTIMATED, armsInterventionsModule interventions name: Learning through Play Plus, outcomesModule primaryOutcomes measure: Recruitment Rate, primaryOutcomes measure: Attrition Rate, primaryOutcomes measure: Intervention attendance log, secondaryOutcomes measure: Positive and Negative Syndrome Scale, secondaryOutcomes measure: Psychotic Rating Scale, secondaryOutcomes measure: Parenting Stress Index, secondaryOutcomes measure: Maternal Attachment Inventory, secondaryOutcomes measure: Knowledge attitude and practices of Child Development, secondaryOutcomes measure: Calgary Depression Scale, secondaryOutcomes measure: Social and Occupational Functioning Scale, secondaryOutcomes measure: Euro-Qol 5 Dimensions, secondaryOutcomes measure: Client Service Receipt Inventory, secondaryOutcomes measure: Ages and Stages Questionnaire, secondaryOutcomes measure: Manchester Assessment of Caregiver-Infant Interaction, secondaryOutcomes measure: Bayley Scale of infant development, secondaryOutcomes measure: Child Height, secondaryOutcomes measure: Child Weight, secondaryOutcomes measure: Child head circumference, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06301334, orgStudyIdInfo id: Soh-Med-24-01-11MS, briefTitle: Block and Erector Comparative Study Between Costotransverse Spinae Plane Block in Patients Undergoing Thoracotomy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-08-01, completionDateStruct date: 2024-08-01, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Sohag University, class: OTHER, descriptionModule briefSummary: A thoracotomy requires a very painful incision, involving multiple muscle layers, rib resection and continuous motion as the patient breathes. Treatment of acute post thoracotomy pain is particularly important not only to keep the patient comfortable but also to minimize pulmonary complicationsThough epidural analgesia was once considered as the gold standard for post-thoracotomy pain management, it is not recommended for pain control after thoracotomy surgery because it is associated with high potential risks of dural puncture, nerve lesions, epidural hematoma and hypotension(4). Thoracic paravertebral block (TPVB) and intercostal nerve block are well described and recognized techniques for postoperative analgesia following thoracic surgeries, such as thoracotomy and mastectomy, conditionsModule conditions: Pain Mangement of Thoracotomy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Bupivacaine 0.25% Injectable Solution, outcomesModule primaryOutcomes measure: study aims to compare the analgesic efficacy of CTB and ESPB for post-operative analgesia in patients undergoing thoracotomy., secondaryOutcomes measure: The secondary outcome is the total postoperative morphine consumption, time of first analgesic,, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06301321, orgStudyIdInfo id: 461_2566, briefTitle: The Evaluation and Comparison of BCR-ABL p210 mRNA Transcripts (%IS Unit) Results Between Dr. PCR™ BCR-ABL1 Major IS Detection Kit (Optolane) and QXDx™ BCR-ABL %IS Kit (Bio-Rad) in Chronic Myeloid Leukemia Patients, acronym: BCR-ABL1, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-20, primaryCompletionDateStruct date: 2024-03-30, completionDateStruct date: 2024-07-30, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Siriraj Hospital, class: OTHER, descriptionModule briefSummary: Today, there are many commercial kits for detecting BCR-ABL fusion transcripts. The QXDx™ BCR-ABL %IS kit (Bio-Rad, Hercules, CA, USA) is the first ddPCR-based in vitro diagnostics (IVD) product with the US Food and Drug Administration clearance and European Conformity (CE) mark which launched in 2017. Dr. PCR™ BCR-ABL1 Major IS Detection Kit (Optolane, South Korea) is one of CE-IVD commercial kits based on digital RT-PCR. Both commercial kits are digital PCR-based, also evaluated their correlation, pros and cons in order for users to select a reagents kit that are appropriate for themselves., conditionsModule conditions: Chronic Myelogenous Leukemia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 80, type: ESTIMATED, outcomesModule primaryOutcomes measure: Sensitivity, primaryOutcomes measure: Specificity, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Siriraj hospital, status: RECRUITING, city: Bangkok, zip: 10700, country: Thailand, contacts name: weerapat Owattanapanich, MD, role: CONTACT, phone: 0891081963, email: weerapato36733@gmail.com, contacts name: Wananchi Saisaard, MT, role: CONTACT, phone: 0817141717, email: wern.si12@gmail.com, contacts name: weerapat Owattanapanich, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 13.75398, lon: 100.50144, hasResults: False
protocolSection identificationModule nctId: NCT06301308, orgStudyIdInfo id: 2022021, briefTitle: A Novel Application of 2% Lidocaine Injection for Male Rigid cycstoscopy-a Patient-blinded Randomised Trial, statusModule overallStatus: WITHDRAWN, startDateStruct date: 2023-10-01, primaryCompletionDateStruct date: 2024-02-29, completionDateStruct date: 2024-02-29, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Second Xiangya Hospital of Central South University, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to learn about a novel application of lidocaine injection in male patients who needs rigid cycstoscopy test. The main question it aims to answer is:Does New Application of Lidocaine Liquid Provide Pain Relief for Patients During Cystoscopy? Before the cycstoscopy,Participants will be randomly divided into three different anesthesia mode groups,namely are Group A (intraurethral lidocaine gel alone), Group B (intraurethral lidocaine gel + lidocaine 2% injection), and Group C (intraurethral lidocaine gel + liquid paraffinl).Patients only need to prepare and cooperate according to routine surgical operations，which is group B or group C., conditionsModule conditions: Bladder Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: FACTORIAL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 0, type: ACTUAL, armsInterventionsModule interventions name: Intraurethral lidocaine gel alone, interventions name: Intraurethral lidocaine gel + lidocaine 2% injection, interventions name: intraurethral lidocaine gel + liquid paraffinl, outcomesModule primaryOutcomes measure: Access the pain score using the Visual Analogue Scale (VAS), secondaryOutcomes measure: Postoperative complications, eligibilityModule sex: MALE, maximumAge: 50 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: The second xiangya hospital, city: Changsha, state: Hunan, zip: 410000, country: China, geoPoint lat: 28.19874, lon: 112.97087, documentSection largeDocumentModule largeDocs typeAbbrev: Prot_SAP_ICF, hasProtocol: True, hasSap: True, hasIcf: True, label: Study Protocol, Statistical Analysis Plan, and Informed Consent Form, date: 2024-01-01, uploadDate: 2024-03-03T08:40, filename: Prot_SAP_ICF_000.pdf, size: 387410, hasResults: False
protocolSection identificationModule nctId: NCT06301295, orgStudyIdInfo id: 2402-017-136, briefTitle: Feasibility of Targeted Bronchial Washing Fluid for Molecular Testing With Next Generation Sequencing in Patients Suspicious of Early-stage Lung Cancer, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2025-12-31, completionDateStruct date: 2026-12-31, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Pusan National University Hospital, class: OTHER, descriptionModule briefSummary: This is a single center, clinical trial evaluating the relevance of intratumoral washing for detection of generic alteration with Next Generation Sequencing., conditionsModule conditions: Lung Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Ultarthin bronchoscopy with intratumoral washing, outcomesModule primaryOutcomes measure: Genetic alteration with Next Generation Sequencing detection rate in intratumoral washing fluid, secondaryOutcomes measure: Concordance rate of genetic alteration with Next Generation Sequencing detection rate among intratumoral washing fluid, plasma, and tissue, secondaryOutcomes measure: Turn-around time, secondaryOutcomes measure: Genetic alteration with Next Generation Sequencing sensitivity & specificity in intratumoral washing fluid, eligibilityModule sex: ALL, minimumAge: 20 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06301282, orgStudyIdInfo id: 2021-02341, briefTitle: Electroencephalographic Signatures of Neuropsychiatric Fluctuations in Parkinson's Disease, acronym: Transition, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-03-03, primaryCompletionDateStruct date: 2025-12, completionDateStruct date: 2025-12, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: University Hospital, Geneva, class: OTHER, descriptionModule briefSummary: Dopaminergic replacement therapy while efficient at reducing symptoms of Parkinson's disease is however often associated with motor and non-motor fluctuations which have a severe impact on patient quality of life. To date, the interplay between cortical activity linked to motor and non-motor symptoms and Parkinson's disease fluctuations linked to dopaminergic medication remain poorly understood.The aim of the study is to characterize the cortical electroencephalographic oscillatory correlates of Parkinson's disease motor and non-motor fluctuations and the temporal dynamics of their dopaminergic modulation.For this purpose, the investigators will apply an innovative approach using the differential non-linear temporal dynamics of motor and non-motor state during the transition from the dopaminergic withdrawal phase (i.e. OFF-levodopa state) to the dopaminergic effect phase (i.e. ON-levodopa state) following an acute levodopa administration.This research will allow to precisely disentangle the network dynamics subtending motor and non-motor symptoms of Parkinson's disease as well as precisely identify the electroencephalographic spectral modulations explaining the neuropsychiatric effects of levodopa. The identification of such biomarkers could pave the way toward innovative therapeutic approaches such as neurofeedback and transmagnetic stimulation., conditionsModule conditions: Parkinson Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: assessment during the transition between OFF-levodopa (i.e. withdrawal of levodopa phase) and ON-levodopa (i.e. effect of Levodopa phase)states, outcomesModule primaryOutcomes measure: Correlation of electroencephalographic resting-state oscillatory activity with neuropsychiatric clinical scores during the levodopa challenge, secondaryOutcomes measure: Correlation of electroencephalographic resting-state oscillatory activity with motor scores during the levodopa challenge, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University Hospital, Geneva, status: RECRUITING, city: Geneva, zip: 1204, country: Switzerland, contacts name: Vanessa Fleury, MD, role: CONTACT, phone: +41223728337, email: Vanessa.FleuryNissen@hcuge.ch, geoPoint lat: 46.20222, lon: 6.14569, hasResults: False
protocolSection identificationModule nctId: NCT06301269, orgStudyIdInfo id: 202312124RINA, briefTitle: A Study on Self-Compassion,Depression,and Quality of Life Among Primary Caregivers of People With Dementia, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-10, primaryCompletionDateStruct date: 2024-05-30, completionDateStruct date: 2024-07-30, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: National Taiwan University Hospital, class: OTHER, descriptionModule briefSummary: The goal of this observational study is to investigate the correlation between self-compassion, depression, and quality of life among primary caregivers of persons with dementia.The main questions it aims to answer are:1. What is the current status of self-compassion, depression, and quality of life among primary caregivers of persons with dementia?2. Are there differences in self-compassion, depression, and quality of life among primary caregivers of persons with dementia based on different background variables?3. What is the correlation between self-compassion, depression, and quality of life among primary caregivers of persons with dementia?Participants will fill out the questionnaire to complete the study., conditionsModule conditions: Dementia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: FAMILY_BASED, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 160, type: ESTIMATED, armsInterventionsModule interventions, outcomesModule primaryOutcomes measure: Self-Compassion Scale, primaryOutcomes measure: PHQ-9 Scale, primaryOutcomes measure: Quality-of-Life Scale, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 99 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: National Taiwan University Hospital, status: RECRUITING, city: Taipei, zip: 100, country: Taiwan, contacts name: wen lin YE, role: CONTACT, phone: +886-2312-3456, email: vovo951357@ntuh.gov.tw, geoPoint lat: 25.04776, lon: 121.53185, hasResults: False
protocolSection identificationModule nctId: NCT06301256, orgStudyIdInfo id: I8F-NS-I002, briefTitle: Evaluate the Efficacy of TIRZEPATIDE for the Treatment of Moderate to Severe HS Hidradenitis Suppurativa, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-11, primaryCompletionDateStruct date: 2025-03-11, completionDateStruct date: 2025-03-11, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Florida Academic Centers Research and Education, LLC, class: INDUSTRY, descriptionModule briefSummary: The purpose of this study is to determine the clinical efficacy and safety of tirzepatide in subjects with moderate to severe hidradenitis suppurativa. The study will be conducted over 24 weeks on active therapy followed by a eight-week observational follow-up visit. The total length of the study will be 32 weeks ., conditionsModule conditions: Hidradenitis Suppurativa, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: TIRZEPATIDE, outcomesModule primaryOutcomes measure: Hidradenitis Suppurativa Clinical Response (HiSCR) 50%, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06301230, orgStudyIdInfo id: PLET-2022, briefTitle: Home- vs. Hospital-based Surgical Training, statusModule overallStatus: COMPLETED, startDateStruct date: 2020-09-01, primaryCompletionDateStruct date: 2021-12-31, completionDateStruct date: 2021-12-31, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Clarunis - Universitäres Bauchzentrum Basel, class: OTHER, collaborators name: University of Basel, descriptionModule briefSummary: The purpose of this study was to assess the effect of training with a personal, portable laparoscopic endo-trainer (PLET) on residents' laparoscopic skills. All participants were randomised to either a home- or hospital-based PLET training group and surgical skill performance was assessed using five laparoscopic exercises. Endpoints consisted ofsubjective and objective assessment ratings as well as exercise time and qualitative data up to 12 weeks. The primary outcome was the difference in exercise time and secondary outcomes included performance scores as well as qualitative data., conditionsModule conditions: Surgical Training, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 24, type: ACTUAL, armsInterventionsModule interventions name: Portable Laparoscopic Trainer (PLET), outcomesModule primaryOutcomes measure: Exercise time, primaryOutcomes measure: Assessment rating, secondaryOutcomes measure: Qualitative feedback, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Clarunis Universitäres Bauchzentrum Basel, city: Basel, zip: 4002, country: Switzerland, geoPoint lat: 47.55839, lon: 7.57327, hasResults: False
protocolSection identificationModule nctId: NCT06301217, orgStudyIdInfo id: NO: PT. BU. EC. 7, briefTitle: Are Axioscapular Muscles Activity and Cervical Curvature Associated With Disability in Neck Pain, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-12-17, primaryCompletionDateStruct date: 2024-03-10, completionDateStruct date: 2024-03-20, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Delta University for Science and Technology, class: OTHER, descriptionModule briefSummary: Despite the important role of axioscapular muscles electromyography and cervical posture as outcomes for the management of chronic neck non specific pain, there is gab of evidence that highlight their association to the commonly used neck disability index. The quest to improve outcomes for individuals suffering from chronic nonspecific neck pain is underscored by the need to identify key prognostic variables that can guide clinical decision-making and intervention strategies. This study seeks to bridge the gap in research by examining the association between neck disability index score, cervical sagittal curvature, and axioscapular muscles electromyography in forms of both trapezius and levator scapula root mean squares to indicate muscular activities and median frequencies to indicate muscular fatigue., conditionsModule conditions: Neck Pain, conditions: Electromyohgraph, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 60, type: ACTUAL, armsInterventionsModule interventions name: There is no intervention, outcomesModule primaryOutcomes measure: Neck disability, primaryOutcomes measure: Curvature angle of the cervical spine, primaryOutcomes measure: root-mean-square value (RMS) of Surface electromyography for both upper trapezius and levator scapula, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Delta university for science and technology, city: Gamasa, state: Dakahleya, zip: 7731168, country: Egypt, geoPoint lat: 31.44112, lon: 31.53675, hasResults: False