hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06368076, orgStudyIdInfo id: H-23065096, briefTitle: High-intensity Interval Training in Patients With Spinal Muscular Atrophy, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-09, primaryCompletionDateStruct date: 2024-08, completionDateStruct date: 2025-01, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Rigshospitalet, Denmark, class: OTHER, descriptionModule briefSummary: Patients with spinal muscular atrophy who are wheelchair users often experience lower back - and gluteal pain, reduced sleep quality, constipation and reduced quality of life - symptoms that regular exercise could potentially alleviate. However, only very little research has been done on exercise for patients who are wheelchair users. The aim of this study is to explore the impact of cycle exercise on patients with spinal muscular atrophy., conditionsModule conditions: Spinal Muscular Atrophy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: Exercise, outcomesModule primaryOutcomes measure: Questionnaire on fatigue, primaryOutcomes measure: Questionnaire on pain., primaryOutcomes measure: Questionnaire on constipation, primaryOutcomes measure: Questionnaire on quality of life, primaryOutcomes measure: Questionnaire on sleep quality, secondaryOutcomes measure: Blood sample, secondaryOutcomes measure: Blood sample, secondaryOutcomes measure: Blood sample, secondaryOutcomes measure: Blood sample, secondaryOutcomes measure: Blood sample, secondaryOutcomes measure: Blood sample, secondaryOutcomes measure: Blood sample, secondaryOutcomes measure: Blood sample, secondaryOutcomes measure: Blood sample, secondaryOutcomes measure: Blood sample, secondaryOutcomes measure: MRI scan liver size, secondaryOutcomes measure: MR-elastography, secondaryOutcomes measure: MRI scan liver steatosis, secondaryOutcomes measure: Ultrasound scan, secondaryOutcomes measure: MRI scan, secondaryOutcomes measure: MRI scan, secondaryOutcomes measure: Exercise test, secondaryOutcomes measure: Motorscore, eligibilityModule sex: ALL, minimumAge: 15 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Rigshospitalet, status: RECRUITING, city: Copenhagen, zip: 2100, country: Denmark, contacts name: Sophia Frølich, stud.med, role: CONTACT, phone: + 45 3545 3561, email: sophia.vera.froelich.01@regionh.dk, contacts name: Noémie Receveur, stud.med, role: CONTACT, phone: +4535453561, email: noemie.anne-marie.receveur.03@regionh.dk, geoPoint lat: 55.67594, lon: 12.56553, hasResults: False
protocolSection identificationModule nctId: NCT06368063, orgStudyIdInfo id: HE-202301, briefTitle: The Study of Huaier Granule in Postoperative Adjuvant Therapy of Resectable Pancreatic Cancer, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2026-03, completionDateStruct date: 2028-03, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-25, sponsorCollaboratorsModule leadSponsor name: Health Science Center of Xi'an Jiaotong University, class: OTHER, collaborators name: LinkDoc Technology (Beijing) Co. Ltd., collaborators name: Huazhong University of Science and Technology, descriptionModule briefSummary: The study is a multicenter, prospective clinical study aimed at evaluating the efficacy and safety of Huaier Granule in postoperative adjuvant treatment of resectable pancreatic cancer, conditionsModule conditions: Pancreatic Cancer Resectable, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 642, type: ESTIMATED, armsInterventionsModule interventions name: Huaier granule, interventions name: chemotherapy drugs, outcomesModule primaryOutcomes measure: Disease-free survival, secondaryOutcomes measure: Overall survival, secondaryOutcomes measure: Progression-free survival, secondaryOutcomes measure: The incidence and severity of adverse events (AE) and severe adverse events (SAE), secondaryOutcomes measure: The incidence and severity of ADR, severe adverse reactions (SADR), suspicious and unexpected severe adverse reactions (SUSAR), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06368037, orgStudyIdInfo id: DragonFire-02, briefTitle: Feasibility Study of the DragonFire for Hypertrophic Obstructive Cardiomyopathy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-08, primaryCompletionDateStruct date: 2025-06, completionDateStruct date: 2026-06, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Hangzhou Valgen Medtech Co., Ltd, class: INDUSTRY, descriptionModule briefSummary: This study is a prospective, single-center, single-group design exploratory clinical research. No control group is set, and only subjects meeting the indications of the study device are treated. After patients sign informed consent, they are screened, and those meeting the inclusion criteria are enrolled. The treatment involves using myocardial radiofrequency ablation system and catheter-based myocardial radiofrequency ablation needle and its guidance system for treating obstructive hypertrophic cardiomyopathy. All subjects are followed up before discharge, and at 30 days, 3 months, 6 months, and 12 months postoperatively., conditionsModule conditions: Obstructive Hypertrophic Cardiomyopathy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 10, type: ESTIMATED, armsInterventionsModule interventions name: DragonFire Transcatheter Myocardial Radiofrequency Ablation System, outcomesModule primaryOutcomes measure: The rate of freedom from major adverse events at 30 days postoperatively, primaryOutcomes measure: The success rate of treatment at 6 months postoperatively, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Northern Theater Command General Hospital of the Chinese People's Liberation Army, city: Shenyang, country: China, geoPoint lat: 41.79222, lon: 123.43278, hasResults: False
protocolSection identificationModule nctId: NCT06368024, orgStudyIdInfo id: CL-12-600, briefTitle: Establishment of Delphi-MD Safety Performance and Reliability, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-11-28, primaryCompletionDateStruct date: 2023-11-28, completionDateStruct date: 2023-11-28, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-26, sponsorCollaboratorsModule leadSponsor name: QuantalX Neuroscience, class: INDUSTRY, descriptionModule briefSummary: A retrospective analysis of collected datasets. In this study we aim to establish Delphi-MD's safety and performance reliability for assessment and monitoring of Transcranial Magnetic Stimulation (TMS) Evoked Potentials (TEPs) as neurophysiological measurements., conditionsModule conditions: Neurologic Disorder, conditions: Healthy, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: RETROSPECTIVE, enrollmentInfo count: 263, type: ACTUAL, armsInterventionsModule interventions name: This is a retrospective analysis study of data collected with a diagnostic medical device, outcomesModule primaryOutcomes measure: Cortical Excitability, primaryOutcomes measure: Specific Peak Amplitudes, primaryOutcomes measure: GMFP, eligibilityModule sex: ALL, minimumAge: 50 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: QuantalX Neuroscience Ltd., city: Kfar Saba, state: Center, zip: 4453001, country: Israel, geoPoint lat: 32.175, lon: 34.90694, hasResults: False
protocolSection identificationModule nctId: NCT06368011, orgStudyIdInfo id: MustafaKU-CINCINOGLU-001, briefTitle: The Impact of Acceptance and Commitment Therapy on Stigmatization, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2023-04-15, primaryCompletionDateStruct date: 2023-07-31, completionDateStruct date: 2024-06-30, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Mustafa Kemal University, class: OTHER, descriptionModule briefSummary: The goal of study is to determine the effect of acceptance and commitment therapy-based psychoeducation on the level of stigmatization applied to relatives of schizophrenia patients.Type of study: This study was planned as a pretest-posttest quasi-experimental design with an observation and control group.Participants: The population of the study consisted of the relatives of schizophrenia patients who were registered and actively attending the Community Mental Health Center in a state hospital in Ankara.Intervention: Before the psychoeducation process started, personal information form and scales were applied to the relatives of the patients in the experimental and control groups. An ACT-based psychoeducation program consisting of 8 sessions was applied to the experimental group. each session lasted approximately 90 minutes. The control group did not receive any intervention. After the psychoeducation, the scales were reapplied to the experimental and control groups. In addition, the experimental group was asked to fill out the psychoeducation evaluation form. The scales were reapplied to the experimental group after the 1-month follow-up study and evaluated., conditionsModule conditions: Stigmatization, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: PREVENTION, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 36, type: ESTIMATED, armsInterventionsModule interventions name: acceptance and commitment therapy, outcomesModule primaryOutcomes measure: Stigma Scale for Relatives of Patients with Schizophrenia, primaryOutcomes measure: Stigma Scale for Relatives of Patients with Schizophrenia, primaryOutcomes measure: Stigma Scale for Relatives of Patients with Schizophrenia, secondaryOutcomes measure: Stigmatization Scale, secondaryOutcomes measure: Stigmatization Scale, secondaryOutcomes measure: Stigmatization Scale, eligibilityModule sex: ALL, minimumAge: 18 Months, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hatay Mustafa Kemal Üniversitesi, city: Hatay, country: Turkey, geoPoint lat: 38.40227, lon: 27.10486, hasResults: False
protocolSection identificationModule nctId: NCT06367998, orgStudyIdInfo id: PC24MISV0017, briefTitle: The Effect of Pregabalin on Shoulder Pain of Patients With Central Sensitization Who Undergo Arthroscopic Rotator Cuff Repair, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2025-05-01, completionDateStruct date: 2026-05-01, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: The Catholic University of Korea, class: OTHER, collaborators name: Viatris Korea, descriptionModule briefSummary: This study aims to investigate the effects of Pregabalin intake on shoulder pain management in patients with central sensitization undergoing arthroscopic rotator cuff repair. Although Pregabalin is known to be effective in controlling pain after shoulder arthroscopy, research on its efficacy in pain management for patients with central sensitization is scarce. Utilizing a list that identifies central sensitization, this study will explore whether Pregabalin can reduce postoperative pain in these patients and potentially improve joint mobility, emotional, and physical functioning. A prospective randomized study is planned, with inclusion criteria set for patients aged between 19 and 70 who have undergone arthroscopic rotator cuff repair.The study will compare clinical outcomes up to one year postoperatively between two groups of 38 patients each. The case group will receive standard postoperative medications (NSAIDs) plus Pregabalin oral intake from the day before surgery to six weeks postoperatively, while the control group will receive only the standard postoperative medications without Pregabalin., conditionsModule conditions: Rotator Cuff Tears, conditions: Central Sensitisation, conditions: Neuropathic Pain, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 76, type: ESTIMATED, armsInterventionsModule interventions name: Pregabalin, outcomesModule primaryOutcomes measure: VAS pain score, secondaryOutcomes measure: Constant shoulder score, secondaryOutcomes measure: American shouler and elbow surgeons (ASES) score, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 69 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06367972, orgStudyIdInfo id: 2024-0070, secondaryIdInfos id: NCI-2024-03278, type: OTHER, domain: NCI-CTRP Clinical Registry, briefTitle: A Randomized Phase II Basket Trial EXTENDing Efficacy of Systemic Therapy With Local Consolidative Therapy for OligoProgressive Metastatic Disease (EXTEND-OP), statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-10-31, primaryCompletionDateStruct date: 2028-10-10, completionDateStruct date: 2030-10-10, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: M.D. Anderson Cancer Center, class: OTHER, descriptionModule briefSummary: To find out if local consolidation therapy (such as radiation therapy with or without other local therapies such as surgery, ablation \[the removal or destruction of a body part or tissue or its function\], or embolization \[a procedure that uses particles, such as tiny gelatin sponges or beads, to block a blood vessel\]) to all progressive sites of disease can help to control the disease compared with next-line systemic therapy., conditionsModule conditions: OligoProgressive Metastatic Disease, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: Local Consolidation Therapy, interventions name: Next-line Systemic Therapy, outcomesModule primaryOutcomes measure: Safety and adverse events (AEs), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: MD Anderson Cancer Center, city: Houston, state: Texas, zip: 77030, country: United States, contacts name: Ethan Ludmir, MD, role: CONTACT, phone: 832-729-0998, email: ebludmir@mdanderson.org, contacts name: Ethan Ludmir, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 29.76328, lon: -95.36327, hasResults: False
protocolSection identificationModule nctId: NCT06367959, orgStudyIdInfo id: 2021-0324, secondaryIdInfos id: NCI-2024-02939, type: OTHER, domain: NCI-CTRP Clinical Trials Registry, briefTitle: Health Benefits of Writing Therapy Among Asian American Cancer Survivors, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-07-27, primaryCompletionDateStruct date: 2026-08-31, completionDateStruct date: 2026-08-31, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: M.D. Anderson Cancer Center, class: OTHER, descriptionModule briefSummary: To learn more about participant experience as a Asian American immigrant breast cancer survivor and how writing about participant experiences may affect participant's health., conditionsModule conditions: Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: SINGLE_GROUP, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 192, type: ESTIMATED, armsInterventionsModule interventions name: Esays, interventions name: Questionnaires, outcomesModule primaryOutcomes measure: Primary Outcome Measure: Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: MD Anderson Cancer Center, status: RECRUITING, city: Houston, state: Texas, zip: 77030, country: United States, contacts name: Qian Lu, MD, PHD, role: CONTACT, phone: 713-745-8324, email: qlu@mdanderson.org, contacts name: Qian Lu, MD, PHD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 29.76328, lon: -95.36327, hasResults: False
protocolSection identificationModule nctId: NCT06367946, orgStudyIdInfo id: XH-24-0093, briefTitle: Mechanism Study of Ventilator-Induced Lung Injury in Elderly People., statusModule overallStatus: RECRUITING, startDateStruct date: 2023-06-01, primaryCompletionDateStruct date: 2024-07-01, completionDateStruct date: 2027-06-30, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, class: OTHER, descriptionModule briefSummary: 1. We collect lung tissues from patients with different ages and confirm that KLK8 expression is positively correlated with age.2. We collect peripheral blood from patients with different ages and duration of mechanical ventilation to explore the correlation between the degree of endothelial/epithelial damage, age and duration of mechanical ventilation., conditionsModule conditions: Ventilator-Induced Lung Injury, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 1000, type: ESTIMATED, armsInterventionsModule interventions name: mechanical ventilation, outcomesModule primaryOutcomes measure: KLK8 concentration of lung tissue, primaryOutcomes measure: Endothelial/epithelial damage index concentration in peripheral blood, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Shanghai Xinhua hospital, status: RECRUITING, city: Shanghai, zip: 200000, country: China, contacts name: Lai Jiang, PhD, role: CONTACT, phone: 13817719616__, email: jianglaimz@sina.com, geoPoint lat: 31.22222, lon: 121.45806, hasResults: False
protocolSection identificationModule nctId: NCT06367920, orgStudyIdInfo id: 2022-02-005, briefTitle: Multicenter Study on Rehabilitation Medical Data for Pediatric Big Brain Development, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-03-23, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Bundang CHA Hospital, class: OTHER, descriptionModule briefSummary: Retrospective study for development of imaging-genetics (brain imaging/genome big data) models and algorithms that are clinically explainable and have high predictive performance in brain research on pediatric developmental disorders, conditionsModule conditions: Pediatric ALL, conditions: Healthy, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 2000, type: ESTIMATED, armsInterventionsModule interventions name: Magnetic Resonance Imaging, Behavioral assessments, outcomesModule primaryOutcomes measure: Brain magnetic resonance imaging, secondaryOutcomes measure: Medical records, eligibilityModule sex: ALL, maximumAge: 20 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: CHA Bundang Medical Center, CHA University, status: RECRUITING, city: Seongnam-si, state: Gyeonggi-do, zip: 463-712, country: Korea, Republic of, contacts name: Minyoung Kim, M.D., Ph.D., role: CONTACT, phone: 82-31-780-1872, email: kmin@cha.ac.kr, geoPoint lat: 37.43861, lon: 127.13778, hasResults: False
protocolSection identificationModule nctId: NCT06367881, orgStudyIdInfo id: MD 185/ 2022, briefTitle: Assessment Of Dose-Dependent Immunomodulatory Effect Of Alveofact With or Without Steroisd In Neonatal RDS, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-08-18, primaryCompletionDateStruct date: 2024-07, completionDateStruct date: 2024-10, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Ain Shams University, class: OTHER, descriptionModule briefSummary: An Exploratory Randomized double-arm controlled trial to evaluate the immunomodulatory effect of low versus high dose of Alveofact with or without Budesonide., conditionsModule conditions: Neonatal Respiratory Distress Syndrome, conditions: Inflammatory Response, conditions: Premature Lungs, conditions: Neutrophil Extracellular Trap Formation, conditions: Preterm Birth, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Alveofact, interventions name: Budesonide, outcomesModule primaryOutcomes measure: Assessment of Neutrophil Extracellular Trap (NET), secondaryOutcomes measure: comparison of Alveolar with whole blood NET formation, secondaryOutcomes measure: Clinical out come, secondaryOutcomes measure: Assessment of Reactive Oxygen Species (ROS), secondaryOutcomes measure: oxygen needs, secondaryOutcomes measure: Hospital stay, eligibilityModule sex: ALL, minimumAge: 1 Day, maximumAge: 2 Days, stdAges: CHILD, contactsLocationsModule locations facility: Egypt Neonatal Intensive Care Units (NICUs), Ain Shams University Cairo, Abbasia, Egypt, 11517, status: RECRUITING, city: Cairo, country: Egypt, contacts name: Ain Shams University, role: CONTACT, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False