hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06345378, orgStudyIdInfo id: IRFMN_PapaGio, briefTitle: Evaluation of the Quality of Care in the Emergency Department by Studying the Appropriateness of Admissions of Patients Accessing the Emergency Department (ASST Papa Giovanni XXIII), statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2021-11-25, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2027-12, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Mario Negri Institute for Pharmacological Research, class: OTHER, descriptionModule briefSummary: The aim of this study is to develop, study and validate a rigorous and sustainable method for assessing the clinical appropriateness of the decision taken in the Emergency Department to admit or not to admit patients., conditionsModule conditions: Quality of Care, conditions: Evaluation, conditions: Emergency Departments, conditions: Appropriateness, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 1200, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Algorithm creation, primaryOutcomes measure: Algorithm validation, primaryOutcomes measure: Algorithm application, primaryOutcomes measure: Appropriateness estimation, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: ASST Papa Giovanni XXIII, city: Bergamo, state: BG, zip: 24127, country: Italy, geoPoint lat: 45.69601, lon: 9.66721, hasResults: False
protocolSection identificationModule nctId: NCT06345352, orgStudyIdInfo id: IRFMN_7520_PoliMI, briefTitle: Evaluation of the Quality of Care in the Emergency Department by Studying the Appropriateness of Admissions of Patients Accessing the Emergency Department (Fondazione IRCCS Ca' Granda Ospedale Maggione Policlinico), statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2020-09-15, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2027-12, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Mario Negri Institute for Pharmacological Research, class: OTHER, descriptionModule briefSummary: The aim of this study is to develop, study and validate a rigorous and sustainable method for assessing the clinical appropriateness of the decision taken in the Emergency Department to admit or not to admit patients., conditionsModule conditions: Quality of Care, conditions: Evaluation, conditions: Emergency Department, conditions: Appropriateness, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 1200, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Algorithm creation, primaryOutcomes measure: Algorithm validation, primaryOutcomes measure: Algorithm application, primaryOutcomes measure: Appropriateness estimation, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, city: Milano, state: MI, zip: 20122, country: Italy, geoPoint lat: 45.46427, lon: 9.18951, hasResults: False
protocolSection identificationModule nctId: NCT06345326, orgStudyIdInfo id: E1-22-3155, briefTitle: Greater Occipital Nerve Block Versus Pulse Radiofrequency in Migraine, acronym: GON-B/PRF, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-01-15, primaryCompletionDateStruct date: 2024-03-30, completionDateStruct date: 2024-04-30, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Adiyaman University Research Hospital, class: OTHER, collaborators name: Ankara City Hospital Bilkent, descriptionModule briefSummary: The aim of the study is to evaluate the clinical efficacy of the repeated greater occipital nerve(GON) blokcs with GON pulse radiofreaquency (PRF), conditionsModule conditions: Migraine, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Prospective observational, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 68, type: ESTIMATED, armsInterventionsModule interventions name: Greater occipital nerve block, outcomesModule primaryOutcomes measure: NRS, secondaryOutcomes measure: Complications, secondaryOutcomes measure: the frequency of headhache, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ankara City Hospital Bilkent, status: RECRUITING, city: Ankara, zip: 06680, country: Turkey, contacts name: Sukriye Dadali, MD, role: CONTACT, phone: +905333316636, email: sukriyedadali@gmail.com, geoPoint lat: 39.91987, lon: 32.85427, hasResults: False
protocolSection identificationModule nctId: NCT06345313, orgStudyIdInfo id: CIRCADIAN RHYTHM, briefTitle: EFFECT OF CIRCADIAN RHYTHM ON INFLAMMATORY PARAMETERS IN UNILATERAL INGUINAL HERNIORRAHIES, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-15, primaryCompletionDateStruct date: 2024-09-15, completionDateStruct date: 2024-10-15, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Ankara City Hospital Bilkent, class: OTHER, descriptionModule briefSummary: To evaluate the inflammatory response of participants who will undergo unilateral inguinal hernia surgery at two different times of the day (08.00-12.00 during the day and 18.00-22.00 at night). The main question it aims to answer is; Is the inflammation response higher in participants who undergo surgery later in the day? Serum inflammatory parameters will be measured in both groups at the preoperative 1st hour and the postoperative 24th hour., conditionsModule conditions: Inflammatory Response, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 70, type: ESTIMATED, armsInterventionsModule interventions name: Day Group, interventions name: Night Group, outcomesModule primaryOutcomes measure: Change of IL6 (interleukin) (ng/ml), secondaryOutcomes measure: Quality of recovery from anesthesia according to difference in circadian rhythm, secondaryOutcomes measure: Change of NLR ( Neutrophil/ Lymphocyte Ratio ), secondaryOutcomes measure: Change of PLR ( Platelet / Lymphocyte Ratio ), secondaryOutcomes measure: Change of SII (Systemic immune-inflammation index ), secondaryOutcomes measure: Change of CRP (C Reactive Protein) (mg/dl), secondaryOutcomes measure: Change of Fibrinogen (mg), secondaryOutcomes measure: Change of Sedimentation (mm/hour), secondaryOutcomes measure: Change of Procalcitonin (µg/l), secondaryOutcomes measure: Change of Ferritin (ml/ng), otherOutcomes measure: Postoperative pain scores according to the difference in circadian rhythm, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ankara Bilkent City Hospital, city: Ankara, state: Cankaya, zip: 06800, country: Turkey, contacts name: Burcu Dikmen Demiryorgan, role: CONTACT, phone: +905067611029, email: burcudikmen325@gmail.com, contacts name: Fatma Kavak Akelma, role: CONTACT, phone: +905327079113, email: fatmakavak@yahoo.com, geoPoint lat: 39.91987, lon: 32.85427, hasResults: False
protocolSection identificationModule nctId: NCT06345300, orgStudyIdInfo id: NCC4309, briefTitle: NALIRIFOX in Combination With Camrelizumab for BRPC: a Prospective, Exploratory Study, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-10, primaryCompletionDateStruct date: 2024-12-12, completionDateStruct date: 2025-12-24, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Cancer Institute and Hospital, Chinese Academy of Medical Sciences, class: OTHER, collaborators name: Jiangsu HengRui Medicine Co., Ltd., descriptionModule briefSummary: The aim of this study is to assess the efficacy and safety of Liposomal Irinotecan, Oxaliplatin, 5-Fluorouracil/Calcium folinate in combination with Camrelizumab for patients with borderline resectable pancreatic cancer, conditionsModule conditions: Borderline Resectable Pancreatic Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Liposomal Irinotecan, Oxaliplatin, 5-Fluorouracil/Calcium folinate in combination with Camrelizumab, interventions name: Liposomal Irinotecan, Oxaliplatin, 5-Fluorouracil/Calcium folinate, outcomesModule primaryOutcomes measure: R0 resection rate, secondaryOutcomes measure: Event free survival (EFS), secondaryOutcomes measure: Overall survival (OS), secondaryOutcomes measure: Objective Response Rate(ORR), secondaryOutcomes measure: Disease Control Rate（DCR）, secondaryOutcomes measure: Safety and tolerability by incidence, severity and outcome of adverse events, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Cancer Institute and Hospital, Chinese Academy of Medical Sciences, status: RECRUITING, city: Beijin, country: China, contacts name: Yongkun Sun, role: CONTACT, phone: 13141276041, email: hsunyk@126.com, hasResults: False
protocolSection identificationModule nctId: NCT06345287, orgStudyIdInfo id: 24/018-4298, briefTitle: Response Adaptive Radiotherapy Following Immunotherapy-based Induction for Non-HPV Related HNSCC, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2025-12-31, completionDateStruct date: 2026-12-31, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Cancer Institute and Hospital, Chinese Academy of Medical Sciences, class: OTHER, descriptionModule briefSummary: The aim of this study is to develop an adaptive radiation therapy plan for locally advanced head and neck squamous cell carcinoma receiving induction therapy containing immunotherapy and chemotherapy. The therapy plan is based on clinical remission, in order to reduce treatment-related toxic side effects without sacrificing clinical efficacy and improve the quality of life of patients., conditionsModule conditions: Head and Neck Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 133, type: ESTIMATED, armsInterventionsModule interventions name: radical radiotherapy (60Gy), interventions name: radical radiotherapy (66Gy), interventions name: radical radiotherapy (70Gy), interventions name: anti-PD-1 or PD-L1 antibody, outcomesModule primaryOutcomes measure: Progression-free survival, secondaryOutcomes measure: Overall survival, secondaryOutcomes measure: Deep partial response, secondaryOutcomes measure: Local-Regional failure survival, secondaryOutcomes measure: Toxicity Adverse events, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, CAMS & PUMC, status: RECRUITING, city: Beijing, country: China, contacts name: Jingbo Wang, Doctor, role: CONTACT, phone: 15811166516, email: wangjingbo303@yahoo.com, geoPoint lat: 39.9075, lon: 116.39723, hasResults: False
protocolSection identificationModule nctId: NCT06345261, orgStudyIdInfo id: 2024-872, briefTitle: Diphenhydramine in Catheter Related Bladder Discomfort, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-04-01, completionDateStruct date: 2025-05-01, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: Diphenhydramine has H1-antihistamine action, it also possesses anti-muscarinic properties. Thus, diphenhydramine might be able to reduce the problem of catheter related bladder discomfort by inhibiting smooth muscle spasm of the urinary bladder via its anti-muscarinic action ., conditionsModule conditions: Catheter Complications, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 104, type: ESTIMATED, armsInterventionsModule interventions name: DiphenhydrAMINE 50 Mg/mL Injectable Solution, interventions name: Saline, outcomesModule primaryOutcomes measure: incidence of catheter related bladder discomfort postoperative, secondaryOutcomes measure: visual analog scale (VAS), eligibilityModule sex: MALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Cairo university, city: Cairo, zip: 11562, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06345248, orgStudyIdInfo id: 2024-854, briefTitle: Laparoscopic-assisted Versus Ultrasonography-guided Transversus Abdominis Plane Block in Laparoscopic Sleeve Gastrectomy, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-04-01, completionDateStruct date: 2025-05-01, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: The transversus abdominis plane (TAP) block, whereby local anesthetic is injected between the internal oblique and transversus abdominis fascia to facilitate blockade of somatic afferents nerves, is an effective, non-narcotic adjunct incorporated into many ERAS protocols. We hypothesized that surgeon delivered LAP-TAPs would be non-inferior to anesthesia-delivered US-TAPs in terms of post-operative pain control, conditionsModule conditions: Transversus Abdominis Plane, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 74, type: ESTIMATED, armsInterventionsModule interventions name: US-TAP, interventions name: LAPTAP, outcomesModule primaryOutcomes measure: morphine needed, secondaryOutcomes measure: first analgesic request time, secondaryOutcomes measure: patients' satisfaction, secondaryOutcomes measure: opioid-associated side effects, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Cairo university, city: Cairo, zip: 11562, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06345222, orgStudyIdInfo id: GETAT 23/05, briefTitle: Examining the Effect of Prolotherapy on Quality of Life and Painkiller Use in Patients With Knee Pain, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-05-01, primaryCompletionDateStruct date: 2023-07-31, completionDateStruct date: 2023-07-31, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Bursa Yüksek İhtisas Education and Research Hospital, class: OTHER_GOV, descriptionModule briefSummary: 92 patients with a diagnosis of primary knee pain of unknown cause followed at the family medicine outpatient clinic and who met our exclusion criteria were invited to the study. When creating patient list, the examination of patients, interviews with patients, as well as their medical records and examinations were used. Patients were divided into two groups: prolotherapy (n=46) and control group (n=46) by simple randomization method. However, when the study started, 32 people in the prolotherapy group and 33 people in the control group of these patients participated in the study. Prior to the research, detailed information was provided about the research in the experimental and control groups and signed consent was obtained from all participants that they volunteered to participate in the research. 5% dectrose was applied to the prolotherapy group by injection method to the pain area. In the control group, existing medical treatments were continued and no injection procedure was performed. Before the research, all participants were evaluated with Case Report Form, Visual Analog Scale (VAS) and Quality of Life Scale Short Form (SF-36). The cases in the experimental and control groups were re-evaluated with the VAS and SF-36 scales at the first month., conditionsModule conditions: The Aim of This Research is to Investigate the Effect of Prolotherapy on Quality of Life and Painkiller Use in Patients With Chronic Knee Pain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Case control study, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 65, type: ACTUAL, armsInterventionsModule interventions name: Prolotherapy, outcomesModule primaryOutcomes measure: change in knee pain with prolotherapy application, primaryOutcomes measure: change in quality of life, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Bursa Yuksek Ihtisas Training and Research Hospital, city: Bursa, state: Türkiye, zip: 16310, country: Turkey, geoPoint lat: 40.19559, lon: 29.06013, hasResults: False
protocolSection identificationModule nctId: NCT06345209, orgStudyIdInfo id: BM-D19, briefTitle: Efficacy and Safety of Sirolimus-coated Coronary Balloon Dilatation Catheter for Coronary Small Vessels, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2025-12, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: BrosMed Medical Co., Ltd, class: INDUSTRY, collaborators name: Chinese Academy of Medical Sciences, Fuwai Hospital, descriptionModule briefSummary: To evaluate the safety and efficacy of a sirolimus-coated coronary balloon dilatation catheter for the treatment of small vessel lesions of primary coronary arteries., conditionsModule conditions: Coronary Artery Disease, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 236, type: ESTIMATED, armsInterventionsModule interventions name: Sirolimus-coated Coronary Balloon Dilatation Catheter, interventions name: Drug-coated Coronary Balloon Dilatation Catheter, outcomesModule primaryOutcomes measure: Late luminal loss (LLL), secondaryOutcomes measure: Device success rate, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06345196, orgStudyIdInfo id: BozokUni, briefTitle: Motivational Interviewing Applied to Individuals With Diabetes, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-15, primaryCompletionDateStruct date: 2024-05-15, completionDateStruct date: 2024-10-15, studyFirstPostDateStruct date: 2024-04-03, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Bozok University, class: OTHER, descriptionModule briefSummary: This study will be conducted using a randomized controlled trial design to evaluate the effect of online individual motivational interviewing on well-being, stress and difficulties in individuals with diabetes. The study will be conducted between March 2024 and March 2025 with individuals with Type 2 Diabetes who are followed up in Yozgat Bozok University Health Practice and Research Center Internal Medicine Polyclinic. The motivational interview group will receive a motivational interview once a week, lasting a maximum of 40 minutes, consisting of a total of four sessions. Chi-square (X2), t-test, repeated measures analysis of variance, Pearson correlation coefficient, partial eta-square and linear regression analysis will be used to evaluate the data., conditionsModule conditions: Motivational Interviewing, conditions: Stress, conditions: Well-Being, Psychological, conditions: Diabetes Mellitus, conditions: Type2diabetes, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 66, type: ESTIMATED, armsInterventionsModule interventions name: motivational interview, outcomesModule primaryOutcomes measure: Change in coping with stress, secondaryOutcomes measure: State of Well-Being Change, otherOutcomes measure: Changing Strength and Difficulties in Diabetes, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 85 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Akdağmadeni School of Health, status: RECRUITING, city: Yozgat, country: Turkey, contacts name: Betül Bal, role: CONTACT, phone: 0 (354) 314 14 15, email: betul.bal@yobu.edu.tr, geoPoint lat: 39.82, lon: 34.80444, locations facility: Bozok University, status: RECRUITING, city: Yozgat, country: Turkey, contacts name: Betül Bal, role: CONTACT, phone: 0 (354) 314 14 15, email: betul.bal@yobu.edu.tr, geoPoint lat: 39.82, lon: 34.80444, hasResults: False