protocolSection identificationModule nctId: NCT06341270, orgStudyIdInfo id: 2024HX1564, briefTitle: Efficacy of TEAS on Postoperative Pain and Recovery in Patients Undergoing Hepatectomy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-20, primaryCompletionDateStruct date: 2026-04-20, completionDateStruct date: 2026-12-20, studyFirstPostDateStruct date: 2024-04-02, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: West China Hospital, class: OTHER, descriptionModule briefSummary: The purpose of this study is to access the effect of transcutaneous electrical acupoint stimulation on postoperative pain in patients undergoing hepatectomy, conditionsModule conditions: Liver Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Patients who meet the enrollment criteria will be randomized 1:1 to either the transcutaneous electrical acupoint stimulation (TEAS）or the sham groups using a computer-generated random number table. After the randomization, use the opaque envelope, hide each group envelope into an opaque envelope, the envelope outside the code, will be sealed to the researcher, when the study, if the inclusion criteria, then open the corresponding numbered envelope, and intervene according to the group scheme in the envelope., primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: Blinding of participants will be maintained throughout the observation period. The sham group will receive electrode attachment but without stimulation,Throughout the study, for adequate blinding, an opaque tape will be applied to the patient's skin above the electrodes, and the patient's target acupoints will be wrapped in a blanket. All patients will be informed that they might or might not feel a tingling sensation around the acupoints when the TEAS device is working. The patients should not be unblinded until the statistical analysis of the study data is completed., whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 524, type: ESTIMATED, armsInterventionsModule interventions name: transcutaneous electrical acupoint stimulation, interventions name: sham transcutaneous electrical acupoint stimulation, outcomesModule primaryOutcomes measure: The incidence of moderate to severe pain (NRS ≥ 4) during movement (i.e. cough or take three deep breaths) at 24 hours after surgery, secondaryOutcomes measure: The incidence of moderate to severe pain (NRS ≥ 4) during movement (i.e. cough or take three deep breaths) at 48 and 72 hours after surgery, secondaryOutcomes measure: The incidence of moderate to severe pain (NRS ≥ 4) at rest at 24, 48 and 72 hours after surgery, secondaryOutcomes measure: Pain scores of movement-evoked pain at postoperative 24,48 and 72 hours, secondaryOutcomes measure: Pain scores of pain at rest at 24, 48 and 72 hours postoperatively, secondaryOutcomes measure: The cumulative morphine consumption at 24, 48, and 72 hours postoperatively, secondaryOutcomes measure: The incidence of postoperative nausea and vomiting during the first 24,48,72 hours, secondaryOutcomes measure: The incidence of a composite of postoperative pulmonary complications during hospitalization, secondaryOutcomes measure: Quality of Recovery Scale Score at 24, 48, and 72 hours after surgery, secondaryOutcomes measure: Time of Bowel function recovery, secondaryOutcomes measure: Length of hospital stay, secondaryOutcomes measure: The postoperative sleep quality score, secondaryOutcomes measure: The anxiety and depression scores, secondaryOutcomes measure: The incidence of chronic postsurgical pain (CPSP), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: West China Hospital, city: Chengdu, state: Sichuan, zip: 610041, country: China, contacts name: Chunling Jiang, PhD, role: CONTACT, phone: 18980601096, email: jiang_chunling@yahoo.com, geoPoint lat: 30.66667, lon: 104.06667, hasResults: False