hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06325332, orgStudyIdInfo id: RSV00080, briefTitle: BEYFORTUS™ (Nirsevimab) Effectiveness Against Medically-Attended RSV Events in Infants (BEAR Study), acronym: BEAR, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-04-01, completionDateStruct date: 2025-04-01, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-04-08, sponsorCollaboratorsModule leadSponsor name: Sanofi Pasteur, a Sanofi Company, class: INDUSTRY, descriptionModule briefSummary: The primary objectives of the study are: To estimate the effectiveness of nirsevimab against polymerase chain reaction (PCR)-confirmed RSV (1) lower respiratory tract (LRTD) and (2) related medical encounters.the secondary objectives are:1. To estimate the effectiveness of nirsevimab against medical encounters with a respiratory related diagnosis.2. To estimate the effectiveness of nirsevimab against medical encounters with an LRTD diagnosis.3. To estimate the impact of nirsevimab on PCR-confirmed RSV.4. To estimate the impact of nirsevimab on medical encounters with an otitis media diagnosis.5. To estimate the impact of nirsevimab on antibiotic prescription., conditionsModule conditions: Respiratory Syncytial Virus, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 33000, type: ESTIMATED, armsInterventionsModule interventions name: Nirsevimab, outcomesModule primaryOutcomes measure: Incidence of first episodes of polymerase chain reaction (PCR)-confirmed RSV with an lower respiratory tract disease (LRTD), primaryOutcomes measure: Number of medical encounters associated with the first episode of PCR-confirmed RSV with a LRTD diagnosis, secondaryOutcomes measure: Number of respiratory-related medical encounters, secondaryOutcomes measure: Number of respiratory-related medical encounters for LRTD by ICD-10 codes, secondaryOutcomes measure: Incidence of PCR-confirmed RSV (first occurrence of season), secondaryOutcomes measure: Number of medical encounters for otitis media by ICD-10 codes, secondaryOutcomes measure: Number of antibiotic prescriptions by National Drug Code (NDC) codes, eligibilityModule sex: ALL, minimumAge: 0 Days, maximumAge: 12 Months, stdAges: CHILD, contactsLocationsModule locations facility: Kaiser Permanente Northern California: Site number 0001, status: RECRUITING, city: Oakland, state: California, zip: 94612, country: United States, geoPoint lat: 37.80437, lon: -122.2708, hasResults: False
protocolSection identificationModule nctId: NCT06325280, orgStudyIdInfo id: Pro00132542, briefTitle: Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2026-12-31, completionDateStruct date: 2027-12-31, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: University of Alberta, class: OTHER, descriptionModule briefSummary: There are many barriers to heart-healthy lifestyles in pediatric patients with acquired and congenital heart disease. Investigators want to further understand how participants heart and skeletal muscles work together during exercise and evaluate the impact on cardiac function. To do this, the investigators will use magnetic resonance imaging (MRI) to scan the heart and skeletal muscles during exercises to assess blood flow, oxygenation and function., conditionsModule conditions: Pediatric ALL, conditions: Congenital Heart Disease, conditions: Heart Transplantation, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: Exercise cardiac MRI Assessment, interventions name: Cardiopulmonary Exercise Test, outcomesModule primaryOutcomes measure: MRI assessment of cardiac structure at rest, primaryOutcomes measure: MRI assessment of cardiac function at rest, primaryOutcomes measure: Maximal exercise MRI assessment of cardiac structure, primaryOutcomes measure: Cardioplumonary Exercise Test, eligibilityModule sex: ALL, minimumAge: 10 Years, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: University of Alberta, city: Edmonton, state: Alberta, zip: T6G 2B7, country: Canada, contacts name: Rae Foshaug, role: CONTACT, phone: 780-407-7499, email: rae.foshaug@albertahealthservices.ca, contacts name: Michael Khoury, MD, role: CONTACT, phone: 780-492-0103, email: khoury1@ualberta.ca, contacts name: Michael Khoury, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 53.55014, lon: -113.46871, hasResults: False
protocolSection identificationModule nctId: NCT06325267, orgStudyIdInfo id: PLC, briefTitle: Clinical Characteristics of Primary Liver Cancer, statusModule overallStatus: RECRUITING, startDateStruct date: 2010-01-01, primaryCompletionDateStruct date: 2024-08-31, completionDateStruct date: 2024-08-31, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, class: OTHER, descriptionModule briefSummary: Primary liver cancer (PLC) is the sixth most common malignancy in the world and the third most common cause of malignancy death. In 2020, there were about 905,677 new cases of PLC worldwide, and 830,180 deaths. Despite the availability of a variety of treatments for PLC, the 5-year net survival rate is still only 5% to 30%. How to effectively reduce the disease burden of PLC is a major public health problem that needs to be solved worldwide. The clinical characteristics and prognosis of PLC caused by different pathogenic factors are different. Therefore, it is of great significance to fully identify the risk factors of PLC, be familiar with the clinical characteristics and prognosis of disease development, and understand the relevant monitoring and follow-up strategies for the prevention and treatment of PLC., conditionsModule conditions: Primary Liver Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 1000, type: ESTIMATED, outcomesModule primaryOutcomes measure: Epidemiological characteristics of overall cohort by liver disease etiology, primaryOutcomes measure: Clinical characteristics of overall cohort by liver disease etiology, secondaryOutcomes measure: Survival rates of overall cohort and different etiologies, secondaryOutcomes measure: Risk factors of prognosis in overall cohort and different etiologies, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Nanjing Drum Tower Hospital, status: RECRUITING, city: Nanjing, state: Jiangsu, zip: 210008, country: China, contacts name: Jie Li, M.D., Ph.D, role: CONTACT, phone: 15863787910, email: lijier@nju.edu.cn, geoPoint lat: 32.06167, lon: 118.77778, hasResults: False
protocolSection identificationModule nctId: NCT06325254, orgStudyIdInfo id: MAFLD, briefTitle: Clinical Characteristics of Metabolic Associated Fatty Liver Disease, statusModule overallStatus: RECRUITING, startDateStruct date: 2010-01-01, primaryCompletionDateStruct date: 2024-08-31, completionDateStruct date: 2024-08-31, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-26, sponsorCollaboratorsModule leadSponsor name: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, class: OTHER, descriptionModule briefSummary: Metabolic associated fatty liver disease (MAFLD), which can lead to liver fibrosis, cirrhosis, liver failure and even hepatocellular carcinoma, poses a significant burden on society. With the improvement of living standards and changes in dietary habits, MAFLD patients show a younger and increasing trend, but there is still no specific drug. The clinical features and prognosis of MAFLD may be different with different metabolic disorder phenotypes and treatment measures. Therefore, further systematic study of the clinical characteristics and prognosis of MAFLD patients will be of great significance for the formulation of corresponding clinical prevention and treatment strategies., conditionsModule conditions: Metabolic Associated Fatty Liver Disease, conditions: Clinical Features, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 3000, type: ESTIMATED, outcomesModule primaryOutcomes measure: Clinical characteristics and follow-up outcomes of MAFLD patients, secondaryOutcomes measure: Clinical characteristics and follow-up outcomes of MAFLD patients under different subgroups, secondaryOutcomes measure: Baseline clinical characteristics MAFLD patients, secondaryOutcomes measure: Risk factors for progression to cirrhosis and hepatocellular carcinoma, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Nanjing Drum Tower Hospital, status: RECRUITING, city: Nanjing, state: Jiangsu, zip: 210008, country: China, contacts name: Jie Li, M.D.,Ph.D, role: CONTACT, phone: 15863787910, email: lijier@nju.edu.cn, geoPoint lat: 32.06167, lon: 118.77778, hasResults: False
protocolSection identificationModule nctId: NCT06325241, orgStudyIdInfo id: 20200048-01H, briefTitle: Validating the Use of Frailty Measurements to Predict Care & Quality of Life, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2022-12-12, primaryCompletionDateStruct date: 2025-03-31, completionDateStruct date: 2025-03-31, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Ottawa Hospital Research Institute, class: OTHER, descriptionModule briefSummary: The aim of this research program is to validate frailty measurements as a risk stratification tool to predict deteriorations in patient-reported outcomes, to gain a better understanding of patient preferences for care within varying degrees of frailty, and to assess differences in frailty measurement between patients and their clinicians.This work will provide a foundation in the development of customized interventions for people with COPD and varying degrees of frailty, with the goal of improving quality of life and optimizing health system service delivery for patients and their care givers., conditionsModule conditions: Chronic Obstructive Pulmonary Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 123, type: ACTUAL, armsInterventionsModule interventions name: No intervention, outcomesModule primaryOutcomes measure: Respiratory Health Related Quality of Life, secondaryOutcomes measure: Burden of symptoms - COPD Assessment, secondaryOutcomes measure: Burden of symptoms - Dyspnea, secondaryOutcomes measure: Psycho-social well being - Anxiety, secondaryOutcomes measure: Psycho-social well being - Depression, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The Ottawa Hospital, General Campus, city: Ottawa, state: Ontario, zip: K1J 0J2, country: Canada, geoPoint lat: 45.41117, lon: -75.69812, documentSection largeDocumentModule largeDocs typeAbbrev: Prot_SAP, hasProtocol: True, hasSap: True, hasIcf: False, label: Study Protocol and Statistical Analysis Plan, date: 2022-09-22, uploadDate: 2022-11-29T13:05, filename: Prot_SAP_000.pdf, size: 617838, largeDocs typeAbbrev: ICF, hasProtocol: False, hasSap: False, hasIcf: True, label: Informed Consent Form: Verbal consent, date: 2022-11-09, uploadDate: 2022-11-29T13:08, filename: ICF_001.pdf, size: 317754, largeDocs typeAbbrev: ICF, hasProtocol: False, hasSap: False, hasIcf: True, label: Informed Consent Form: English Information Sheet, date: 2022-11-09, uploadDate: 2022-11-29T13:11, filename: ICF_002.pdf, size: 161773, hasResults: False
protocolSection identificationModule nctId: NCT06325215, orgStudyIdInfo id: SCaglar, briefTitle: The Effect of Hydrocolloid to Prevent Nasal Injuries in Preterm Infants, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-05-05, primaryCompletionDateStruct date: 2022-10-29, completionDateStruct date: 2022-11-05, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Istanbul University - Cerrahpasa (IUC), class: OTHER, descriptionModule briefSummary: The aim of this study is to evaluate the effect of using hydrocolloid tapes in preventing pressure injuries on the nose and columella regions caused by non-invasive mechanical ventilation (NIMV) in preterm infants., conditionsModule conditions: Pressure Injury, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized Controlled Experimantal, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: DOUBLE, maskingDescription: After providing information about the study to the parents of preterm newborns who met the inclusion criteria, informed consent forms were obtained without disclosing which group their babies would be assigned to. The research outcome measurements were recorded by two nurses working at NICU. Prior to the study, necessary training and information about the form and process were provided to the nurses. The data analysis was conducted by an independent statistician., whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, enrollmentInfo count: 56, type: ACTUAL, armsInterventionsModule interventions name: Hidrocolloid Bant, outcomesModule primaryOutcomes measure: Neonatal Skin Condition Score, primaryOutcomes measure: Pressure İnjury Staging Scale, secondaryOutcomes measure: Neonatal Skin Risk Assessment Scale, eligibilityModule sex: ALL, minimumAge: 24 Weeks, maximumAge: 37 Weeks, stdAges: CHILD, contactsLocationsModule locations facility: Abide-i Hurriyet Cad. Istanbul University-Cerrahpaşa, Florence Nightingale Faculty of Nursing, city: Istanbul, zip: 34381, country: Turkey, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06325189, orgStudyIdInfo id: Rec-42336, briefTitle: Effects of Aerobic Interval Training on Fatigue Level and Functional Performance in Post Angioplasty Patients, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-07-20, primaryCompletionDateStruct date: 2023-12-01, completionDateStruct date: 2023-12-10, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Riphah International University, class: OTHER, descriptionModule briefSummary: The goal of this randomized controlled trial is to determine the effects of aerobic interval training on levels of tiredness and functional performance in post-angioplasty patients. The main question it aims to answer is:Does aerobic interval training reduce fatigue and improve functional performance compared to medication alone in post-angioplasty patients?Participants will:Be randomly assigned to either the control group (medication) or the experimental group (medication + aerobic interval training) Perform aerobic interval training for 30 minutes, three times a week, for six weeks (experimental group only) Complete pre and post-intervention assessments using the fatigue severity scale, the 6-minute walk test, and the one minute sit to stand test Researchers will compare the two groups to see if aerobic interval training leads to significant improvements in fatigue levels and functional performance., conditionsModule conditions: Coronary Artery Disease, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: In this parallel-group randomized controlled trial (RCT), post-angioplasty patients will be assigned to either the control group (receiving standard medication) or the experimental group (receiving medication along with aerobic interval training). The study aims to evaluate the impact of aerobic interval training on fatigue levels and functional performance in these patients., primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: The study was single-blinded, as assessors of the study were kept blind to the intervention group to which the participant was allocated., whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 47, type: ACTUAL, armsInterventionsModule interventions name: Aerobic Interval Training, outcomesModule primaryOutcomes measure: Fatigue Severity Scale, primaryOutcomes measure: Six Minute Walk Test, primaryOutcomes measure: 1 minute sit to stand:, eligibilityModule sex: ALL, minimumAge: 40 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Gulab Devi Chest Hospital, city: Lahore, state: Punjab, zip: 54000, country: Pakistan, geoPoint lat: 31.558, lon: 74.35071, hasResults: False
protocolSection identificationModule nctId: NCT06325176, orgStudyIdInfo id: REC/RCR & AHS/23/0569, briefTitle: Comparative Effects of Cryotherapy and Infrared Light on Pain, Redness, and Healing of Episiotomy Wound, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-20, primaryCompletionDateStruct date: 2024-10-01, completionDateStruct date: 2024-10-15, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Riphah International University, class: OTHER, descriptionModule briefSummary: The study will be a randomized clinical trial and will be conducted in Bahawalpur Victoria Hospital, Bahawalpur. The subjects (n=24) will be divided into two groups. Group A will include 12 postnatal women and for treatment, cryotherapy will be applied for 20 minutes. Group B will include 12 women and receive infrared light, an infrared lamp will be put at a distance of 45 cm from the perineum, and the heat produced with 230 volts for twenty minutes. The participant will be checked after the first five minutes to make sure that she is not being burned. This procedure will be done twice a day for 7 consecutive days., conditionsModule conditions: Episiotomy Wound, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: Cryotherapy, interventions name: Infrared light therapy, outcomesModule primaryOutcomes measure: Numeric Pain Rating Scale, primaryOutcomes measure: The standardized REEDA scale:, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 35 Years, stdAges: ADULT, contactsLocationsModule locations facility: Bahawalpur Victoria Hospital(BVH), status: RECRUITING, city: Bahāwalpur, state: Punjab, zip: 63100, country: Pakistan, contacts name: Ghulam Fatima, PhD*, role: CONTACT, phone: 03034073057, email: ghulam.fatima@riphah.edu.pk, geoPoint lat: 29.4, lon: 71.68333, hasResults: False
protocolSection identificationModule nctId: NCT06325163, orgStudyIdInfo id: MIU-IRB-2223-219, briefTitle: Accuracy of Artificial Intelligence Technology in Detecting Number of Root Canals in Human Mandibular First Molars Obturated and Indicated for Retreatment: Diagnostic Accuracy Experimental Study, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-01-25, primaryCompletionDateStruct date: 2023-10-02, completionDateStruct date: 2023-10-10, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Misr International University, class: OTHER, descriptionModule briefSummary: evaluate the accuracy of new AI technology for detecting root canals in mandibular first molars retreatment cases in comparison to dentist clinical access cavity and CBCT imaging., conditionsModule conditions: Missed Canals, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SEQUENTIAL, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 35, type: ACTUAL, armsInterventionsModule interventions name: CBCT, interventions name: clinical examination under dental operating microscope, interventions name: canal detection AI software (diagnocat), outcomesModule primaryOutcomes measure: Number of canals, secondaryOutcomes measure: linear morphological variations in failed cases, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Misr International University, city: Cairo, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06325150, orgStudyIdInfo id: STUDY00008572, briefTitle: The Impact of Light Exposure on Cognitive Function in Classrooms, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2027-02-01, completionDateStruct date: 2028-02-01, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Michigan State University, class: OTHER, descriptionModule briefSummary: Humans are constantly exposed to a variety of light types, created naturally or through artificial means. Light exposure captured by the eyes impacts many physiological functions in humans, including but not limited to cognitive output, fatigue levels, and mood regulation. The level of impact on cognitive learning from different types of light on undergraduate adult students remains unclear., conditionsModule conditions: Healthy, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: This study will test the effect of light emitting glasses, vs placebo, vs no-glasses to attention in college students. This is a crossover study, where participants will be randomly assigned to one of three groups, and tested in random order. The students will be tested on 2 or 3 different conditions (no glasses, placebo or light emitting glasses). The assignment to each of the groups, and the order of the intervention (+/- glasses) will be randomized.Note-light emitting glasses are not FDA regulated. Because light emitting glasses can change physiology, this is considered a phase 1 clinical trial., primaryPurpose: BASIC_SCIENCE, maskingInfo masking: SINGLE, whoMasked: INVESTIGATOR, enrollmentInfo count: 300, type: ESTIMATED, armsInterventionsModule interventions name: Light emitting glasses, outcomesModule primaryOutcomes measure: Assessment of attention, secondaryOutcomes measure: Determine how time of day impacts attention, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Michigan State University, city: East Lansing, state: Michigan, zip: 48824, country: United States, contacts name: Hanne M Hoffmann, PhD, role: CONTACT, phone: 517-353-1415, email: hanne@msu.edu, geoPoint lat: 42.73698, lon: -84.48387, hasResults: False