protocolSection identificationModule nctId: NCT06372080, orgStudyIdInfo id: 19/SPS/054, briefTitle: Resistance Training and Hydrolyzed Collagen Supplementation in Healthy Young Adults, statusModule overallStatus: COMPLETED, startDateStruct date: 2020-01-06, primaryCompletionDateStruct date: 2021-09-29, completionDateStruct date: 2023-03-31, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Liverpool John Moores University, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to investigate the effects of resistance training with hydrolyzed collagen ingestion on changes in muscle and tendon adaptation in healthy young men and women.The main questions it aims to answer are:* Does resistance training with hydrolyzed collagen ingestion lead to greater changes in tendon properties than resistance training alone?* Does resistance training with hydrolyzed collagen ingestion lead to greater changes in muscle size than resistance training alone?Participants will be randomly assigned to collagen or placebo groups. Participants will perform resistance training three times per week for 10 weeks and hydrolyzed collagen or maltodextrin will be given to collagen or placebo group respectively immediately before each resistance training session. Also, vitamin C will be given to both groups.Researchers will compare collagen and placebo groups to see if hydrolyzed collagen ingestion with resistance exercise would have beneficial effects on changes in muscle and tendon more than resistance training alone. Therefore, using isokinetic dynamometer and ultrasonography, maximal leg strength, morphological, mechanical, and material properties of the patellar tendon and vastus lateralis muscle size and architecture will be assessed., conditionsModule conditions: Healthy Participants, conditions: Nutrition, conditions: Exercise Training, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The study design is a single-blind (participants were unaware of their group allocation), randomized controlled trial., primaryPurpose: BASIC_SCIENCE, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 23, type: ACTUAL, armsInterventionsModule interventions name: Resistance training with hydrolyzed collagen ingestion in healthy young men, interventions name: Resistance training with hydrolyzed collagen ingestion in healthy young women, outcomesModule primaryOutcomes measure: Maximal knee extensor (quadriceps) muscle strength, primaryOutcomes measure: Maximal knee flexor (hamstring) muscle strength, primaryOutcomes measure: Patellar tendon cross-sectional area, primaryOutcomes measure: Patellar tendon stiffness, primaryOutcomes measure: Vastus lateralis (VL) muscle size, primaryOutcomes measure: Vastus lateralis (VL) muscle fascicle length, primaryOutcomes measure: Vastus lateralis (VL) muscle fascicle pennation angle, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 39 Years, stdAges: ADULT, contactsLocationsModule locations facility: Research Institute for Sport and Exercise Sciences, city: Liverpool, state: Merseyside, zip: L3 3AF, country: United Kingdom, geoPoint lat: 53.41058, lon: -2.97794, hasResults: False