hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06375876, orgStudyIdInfo id: 2000034173, secondaryIdInfos id: 15JOVW-22-GG-04755-STOP, type: OTHER_GRANT, domain: Office on Violence Against Women (OVW), briefTitle: Single Session Intervention to Promote Hope, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-04, completionDateStruct date: 2025-04, studyFirstPostDateStruct date: 2024-04-19, lastUpdatePostDateStruct date: 2024-04-26, sponsorCollaboratorsModule leadSponsor name: Yale University, class: OTHER, collaborators name: Office on Violence Against Women (OVW), descriptionModule briefSummary: The purpose of this study is to develop a brief, self-guided single-session intervention (SSI) that targets the development of, or increase in, hope, and pilot test it for the primary outcomes of feasibility, acceptability/likeability, safety, and changes in hope, and the secondary outcomes of self-worth, empowerment, and emotional wellbeing among women experiencing intimate partner violence (IPV). The study will be conducted in 2 stages: intervention development (Intervention Development Stage), and pilot testing the intervention (Pilot Stage). The focus of this registration is the Pilot Stage., conditionsModule conditions: Domestic Violence, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 65, type: ESTIMATED, armsInterventionsModule interventions name: Single-session intervention (SSI), outcomesModule primaryOutcomes measure: Feasibility assessed by percent enrolled, primaryOutcomes measure: Feasibility assessed by time to complete, primaryOutcomes measure: Feasibility assessed by post-intervention survey/process supplement, primaryOutcomes measure: Acceptability/likability assessed using the Program Feeback Scale, primaryOutcomes measure: Safety assessed using end of study survey, primaryOutcomes measure: Change in Hope assessed using Herth Hope Index, primaryOutcomes measure: Change in Hope assessed using Trait Hope Scale, primaryOutcomes measure: Change in Hope assessed using Beck Hopelessness Scale (single item), secondaryOutcomes measure: Change in Self-worth, secondaryOutcomes measure: Change in Empowerment assessed using The Personal Progress Scale-Revised (PPS-R), secondaryOutcomes measure: Change in Emotional wellbeing measured by the Patient Health Questionnaire-2 (PHQ-2), secondaryOutcomes measure: Change in Emotional wellbeing measured by the State Joy Scale, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The Consultation Center at Yale, city: New Haven, state: Connecticut, zip: 06511, country: United States, contacts name: Ashley Clayton, role: CONTACT, phone: 203-623-9830, email: ashley.clayton@yale.edu, geoPoint lat: 41.30815, lon: -72.92816, hasResults: False
protocolSection identificationModule nctId: NCT06375863, orgStudyIdInfo id: 44-2023, briefTitle: QT Changes in Geriatric Patients: a Comparison of Spinal and General Anesthesia, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-03-29, primaryCompletionDateStruct date: 2023-05-29, completionDateStruct date: 2023-05-29, studyFirstPostDateStruct date: 2024-04-19, lastUpdatePostDateStruct date: 2024-04-19, sponsorCollaboratorsModule leadSponsor name: Haseki Training and Research Hospital, class: OTHER, descriptionModule briefSummary: QT interval, defined as the time between the beginning of the QRS complex and the end of the T wave in electrocardiography (ECG), is an indicator of depolarization and repolarization of the myocardium.11 Prolongation of the heart rate corrected QT (QTc) interval reflects electrical instability of ventricles and is associated with life-threatening ventricular arrhythmias, including torsade de pointes, ventricular fibrillation and sudden cardiac death.Spinal anesthesia can cause profound prolongation of the QTc interval due to disparity between lumbar and thoracic sympathetic activity following subarachnoid block. Meanwhile inhalational anesthetics, sevoflurane, isoflurane, and desflurane are known to prolong QTc interval and intravenous anesthetics such as propofol, thiopental, etomidate and ketamin can also cause remarkable prolongation of the QTc interval. Moreover laryngoscopy and intubation may contribute to prolongation of the QTc interval because of the sympathetic stimulation.Over the years it has been occurred an increase in the proportion of elderly population requiring surgical anesthesia. The incidence of ventricular arrhythmias increases in advancing age even in the absence of underlying heart disease and elderly patients have reduced physiological functions and poor tolerance to anesthesia. However the choice of anesthesia type is critical in this population.To the best of knowledge, there was no published study to compare spinal anesthesia and inhalational anesthesia in elderly patients with regard to the QT interval changes. Investigators aimed to investigate the effects of spinal anesthesia on QT, QTc intervals and to compare general anesthesia with sevofluran in elderly patients., conditionsModule conditions: Anesthesia, Spinal, conditions: Sevoflurane, conditions: Long QT Syndrome, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: DIAGNOSTIC, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 58, type: ACTUAL, armsInterventionsModule interventions name: QT and QTc interval, outcomesModule primaryOutcomes measure: QTc interval, secondaryOutcomes measure: QT, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Health Science University, Haseki Training and Research Hospital, city: Istanbul, country: Turkey, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06375850, orgStudyIdInfo id: Effects of topical sesame oil, briefTitle: Effects of Topical Sesame Oil in the Prevention of Peripheral Venous Catheter Phlebitis: Clinical Trial., statusModule overallStatus: RECRUITING, startDateStruct date: 2022-06-05, primaryCompletionDateStruct date: 2025-02-11, completionDateStruct date: 2025-05-11, studyFirstPostDateStruct date: 2024-04-19, lastUpdatePostDateStruct date: 2024-04-19, sponsorCollaboratorsModule leadSponsor name: Hospital Universitario Marqués de Valdecilla, class: OTHER, descriptionModule briefSummary: Cancer is a disease that, despite having a higher cure rate, is currently on the rise, with an increase in the number of diagnoses.For the treatment of these patients a venous access is required, which in the first treatments is of peripheral insertion. These peripheral venous catheter in combination with the highly aggressive treatments for the veins are the cause of the appearance of chemical phlebitis.Phlebitis is an inflammation caused by a combination of factors, whether chemical, perfusion of irritating medication; mechanical, due to the puncture site, type and fixation of the catheter and infectious, caused by the colonization of pathogenic agents whose origin is the skin and that migrate inward.Phlebitis involves an injury to the wall of the vein, and consequently, the patient will also be at risk of thrombus formation, which in turn leads to thrombophlebitis, deep vein thrombosis or pulmonary embolism.The existence of phlebitis involves intense and constant pain, with increased sensitivity and a sensation of heat and swelling.With the use of topical sesame oil, and thanks to its anti-inflammatory properties, the investigators intend to study whether it is effective in preventing the appearance of phlebitis., conditionsModule conditions: Phlebitis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 300, type: ESTIMATED, armsInterventionsModule interventions name: Sesame oil, interventions name: Saline solution, outcomesModule primaryOutcomes measure: Number of phlebitis in oncology patients with peripheral catheter to whom sesame oil is applied topically, secondaryOutcomes measure: Other adverse effects that appear in relation to the topical application of sesame oil in patients with peripheral catheters, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hospital Universitario Marqués de Valdecilla, status: RECRUITING, city: Santander, state: Cantabria, zip: 39008, country: Spain, contacts name: Virginia Meneses Campos, role: CONTACT, phone: +34942202520, email: virginia.meneses@scsalud.es, contacts name: Virginia Meneses Campos, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 43.46472, lon: -3.80444, hasResults: False
protocolSection identificationModule nctId: NCT06375837, orgStudyIdInfo id: bioactive-NCCLs, briefTitle: Comparative Evaluation of an Alkasite-based Restorative Material and Two Different Resin Composites, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-15, primaryCompletionDateStruct date: 2024-06-15, completionDateStruct date: 2026-06-15, studyFirstPostDateStruct date: 2024-04-19, lastUpdatePostDateStruct date: 2024-04-19, sponsorCollaboratorsModule leadSponsor name: Hacettepe University, class: OTHER, descriptionModule briefSummary: The clinical performance of an an alkasite-based restorative material and two different resin composites will be evaluated and compared in non-carious cervical lesions. After recruiting participants with at least three non-carious cervical lesions, all restorations will be placed by a single clinician. Lesions will be divided in three groups: an alkasite-based restorative material (Cention N, Ivoclar Vivadent, Schaan, Liechtenstein (CN)), hybrid resin composite (Gradia Direct Anterior, GC, Tokyo, Japan (GD)) and a highly filled flowable resin composite ((G-aenial Universal Flo, GC, Tokyo, Japan (GF)). All restorative procedures will be conducted according to manufacturers' instructions. Restorations will be scored using FDI criteria. Descriptive statistics will be performed using chi-square tests., conditionsModule conditions: Tooth Diseases, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 33, type: ESTIMATED, armsInterventionsModule interventions name: an alkasite-based restorative material, interventions name: hybrid resin composite, interventions name: a highly filled flowable resin composite, outcomesModule primaryOutcomes measure: Clinical performances of different restorative systems according to FDI criteria (Esthetic properties), secondaryOutcomes measure: Clinical performances of different restorative systems according to FDI criteria (Functional properties), otherOutcomes measure: Clinical performances of different restorative systems according to FDI criteria (Biological properties), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hacettepe University, status: RECRUITING, city: Ankara, country: Turkey, contacts name: Fatma Oz, role: CONTACT, geoPoint lat: 39.91987, lon: 32.85427, hasResults: False
protocolSection identificationModule nctId: NCT06375824, orgStudyIdInfo id: TCM for Pre-COPD, briefTitle: Bufei Recipe Reduces the Incidence Rate of COPD, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2027-04-30, completionDateStruct date: 2027-10-31, studyFirstPostDateStruct date: 2024-04-19, lastUpdatePostDateStruct date: 2024-04-19, sponsorCollaboratorsModule leadSponsor name: Henan University of Traditional Chinese Medicine, class: OTHER, collaborators name: West China Hospital, collaborators name: The First Affiliated Hospital of Zhejiang Chinese Medical University, descriptionModule briefSummary: Establish early TCM prevention and treatment program to reduce the incidence rate of COPD., conditionsModule conditions: Preserved Ratio Impaired Spirometry, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 1100, type: ESTIMATED, armsInterventionsModule interventions name: Bufei Recipe, interventions name: Bufei Recipe placebo, outcomesModule primaryOutcomes measure: Incidence rate of COPD, secondaryOutcomes measure: FVC, secondaryOutcomes measure: FEV1, secondaryOutcomes measure: FEV1% pred, secondaryOutcomes measure: FEV1/FVC, secondaryOutcomes measure: IPAG-Q, secondaryOutcomes measure: LFQ, secondaryOutcomes measure: COPD-PS, secondaryOutcomes measure: CAT, secondaryOutcomes measure: SF-36, secondaryOutcomes measure: Clinical symptoms, secondaryOutcomes measure: Biochemical indicators, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06375798, orgStudyIdInfo id: 2020137, briefTitle: Clinical Study of Breast Conserving Surgery Combined With Intraoperative Radiotherapy for Early Breast Cancer, statusModule overallStatus: RECRUITING, startDateStruct date: 2020-11-19, primaryCompletionDateStruct date: 2026-11-19, completionDateStruct date: 2026-11-19, studyFirstPostDateStruct date: 2024-04-19, lastUpdatePostDateStruct date: 2024-04-19, sponsorCollaboratorsModule leadSponsor name: Hebei Medical University Fourth Hospital, class: OTHER, descriptionModule briefSummary: A Single-center, open, prospective study，for analyzing the local recurrence rate, the incidence of incision complications and the aesthetic effect of intraoperative radiotherapy in early breast cancer patients after breast-conserving surgery., conditionsModule conditions: Breast Cancer, conditions: HER2-negative Breast Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 620, type: ESTIMATED, armsInterventionsModule interventions name: radiotherapy, outcomesModule primaryOutcomes measure: LRFS, eligibilityModule sex: FEMALE, minimumAge: 55 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The Fourth Hospital of Hebei Medical University, status: RECRUITING, city: Shijiazhuang, state: Hebei, country: China, contacts name: qimei wang, attending, role: CONTACT, phone: 18633051639, email: maggie92320@hotmail.com, geoPoint lat: 38.04139, lon: 114.47861, hasResults: False
protocolSection identificationModule nctId: NCT06375785, orgStudyIdInfo id: LSVT-BIG vs Otago, briefTitle: Two Different Exercise Methods in Geriatrics, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-03-01, primaryCompletionDateStruct date: 2023-06-01, completionDateStruct date: 2024-03-01, studyFirstPostDateStruct date: 2024-04-19, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Halic University, class: OTHER, collaborators name: Fenerbahce University, collaborators name: Istanbul Galata University, collaborators name: Biruni University, descriptionModule briefSummary: The aim of the study is to compare slow rhythmic exercises with large amplitude exercises in elderly people, conditionsModule conditions: Elderly People, conditions: Nursing Homes, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 70, type: ACTUAL, armsInterventionsModule interventions name: Otago-based (slow rhythmic) exercise group, interventions name: LSVT BIG-based (large amplitude) exercise group, outcomesModule primaryOutcomes measure: Timed Up &Go Test, primaryOutcomes measure: Performanz Balance System, primaryOutcomes measure: Functional Reaching Test, primaryOutcomes measure: Six Minute Walking Test, primaryOutcomes measure: Tinetti Balance and Gait Assessment, secondaryOutcomes measure: Activity-Specific Balance and Confidence Scale, secondaryOutcomes measure: Five Times Sit to Stand, secondaryOutcomes measure: Montreal Cognitive Assessment Test, secondaryOutcomes measure: KATZ Activities of Daily Living Scale, secondaryOutcomes measure: Clinical Frailty Scale, eligibilityModule sex: ALL, minimumAge: 65 Years, maximumAge: 80 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Haliç University, city: Istanbul, state: Eyüpsultan, country: Turkey, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06375772, orgStudyIdInfo id: 2-DG-02, briefTitle: A Controlled Human Rhinovirus Infection Study of 2-Deoxy-D-Glucose in Healthy Adults, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-02, primaryCompletionDateStruct date: 2024-08-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-04-19, lastUpdatePostDateStruct date: 2024-04-19, sponsorCollaboratorsModule leadSponsor name: G.ST Antivirals GmbH, class: INDUSTRY, descriptionModule briefSummary: 2-DG-02 is a randomized, placebo-controlled, double-blind Phase 2 study to investigate the efficacy and safety of 2-Deoxy-D-Glucose as a pre-exposure prophylaxis using the rhinovirus challenge model in healthy study participants., conditionsModule conditions: Acute Nasopharyngitis, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 128, type: ESTIMATED, armsInterventionsModule interventions name: 2-Deoxy-D-glucose, interventions name: Placebo, outcomesModule primaryOutcomes measure: The difference in the rate of rhinovirus-associated illness between 2-DG and placebo, secondaryOutcomes measure: Number of infected subjects, secondaryOutcomes measure: Difference in percent of infected subjects, secondaryOutcomes measure: Difference in percent of days virus positive, secondaryOutcomes measure: Difference in peak nasal virus load, secondaryOutcomes measure: Difference in AUC nasal virus load, secondaryOutcomes measure: Difference in Total Jackson Symptom Score, secondaryOutcomes measure: Duration of illness, secondaryOutcomes measure: Difference in percent of days Jackson Symptom Score positive, secondaryOutcomes measure: Difference in Peak Jackson Symptom Score, secondaryOutcomes measure: Difference in peak total WURSS-21, secondaryOutcomes measure: Difference in AUC total WURSS-21, secondaryOutcomes measure: Occurrence of adverse events (AEs) and adverse drug-reactions (ADRs), secondaryOutcomes measure: Biodistribution of multiple doses of 2-DG in plasma samples, secondaryOutcomes measure: Biodistribution of multiple doses of 2-DG in nasal wash samples, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 64 Years, stdAges: ADULT, contactsLocationsModule locations facility: Centre for Human Drug Research, status: RECRUITING, city: Leiden, zip: 2333, country: Netherlands, contacts name: Ingrid de Visser- Kamerling, PhD, role: CONTACT, phone: +31 71 5246400, email: clintrials@chdr.nl, geoPoint lat: 52.15833, lon: 4.49306, hasResults: False
protocolSection identificationModule nctId: NCT06375759, orgStudyIdInfo id: XWSSB, briefTitle: Subarachnoid-Subarachnoid (S-S) Bypass Versus Adhesion Lysis in Spinal Arachnoiditis and Syringomyelia, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-04, completionDateStruct date: 2027-04, studyFirstPostDateStruct date: 2024-04-19, lastUpdatePostDateStruct date: 2024-04-19, sponsorCollaboratorsModule leadSponsor name: Xuanwu Hospital, Beijing, class: OTHER, descriptionModule briefSummary: To determine whether Subarachnoid-Subarachnoid (S-S) Bypass results in better patient outcomes with fewer complications and improved quality of life compared to intradural adhesion lysis in individuals with Spinal Arachnoiditis and Syringomyelia., conditionsModule conditions: Syringomyelia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: Subarachnoid-Subarachnoid (S-S) Bypass, interventions name: Intradural Adhesion Lysis, outcomesModule primaryOutcomes measure: complication, secondaryOutcomes measure: improvement or resolution of the syrinx,, secondaryOutcomes measure: ASIA score, secondaryOutcomes measure: Klekamp and Sammi syringomyelia scale, secondaryOutcomes measure: modified Japanese Orthopaedic Association Scores (mJOA), secondaryOutcomes measure: xuanwu syringomyelia scale, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Fengzeng Jian, status: RECRUITING, city: Beijing, state: Beijing, zip: 100053, country: China, contacts name: Yuan Chenghua, role: CONTACT, email: yuanchenghua@ccmu.edu.cn, contacts name: Jian Fengzeng, role: CONTACT, email: jianfengzeng@xwh.ccmu.edu.cn, contacts name: jian guan, dr, role: SUB_INVESTIGATOR, geoPoint lat: 39.9075, lon: 116.39723, hasResults: False
protocolSection identificationModule nctId: NCT06375746, orgStudyIdInfo id: 0091-22-WOMC, briefTitle: The Impact of a Customized Informative Video Prior to Induction of Labor on Anxiety Relieve - a Randomized Controlled Trial, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2024-08-01, completionDateStruct date: 2024-08-31, studyFirstPostDateStruct date: 2024-04-19, lastUpdatePostDateStruct date: 2024-04-19, sponsorCollaboratorsModule leadSponsor name: Wolfson Medical Center, class: OTHER_GOV, descriptionModule briefSummary: To determine whether watching a personalized video prior to medically indicated labor induction among term parturients reduces anxiety levels according to the STAI questionnaire, compared to a standard counselling., conditionsModule conditions: Induction of Labor Affected Fetus / Newborn, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 180, type: ESTIMATED, armsInterventionsModule interventions name: Personalized video, outcomesModule primaryOutcomes measure: STAI questionnaire score, secondaryOutcomes measure: satisfaction questionnaire, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False