hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06290986, orgStudyIdInfo id: Pyrocardan® RCT, briefTitle: Pyrocardan® Implant Arthroplasty or LRTI for Trapeziometacarpal Osteoarthritis, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-09-26, primaryCompletionDateStruct date: 2025-09-30, completionDateStruct date: 2025-09-30, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Herlev and Gentofte Hospital, class: OTHER, descriptionModule briefSummary: This is a randomized controlled trial comparing the Pyrocardan® implant (intervention group) with the standard ligament reconstruction and tendon interposition (LRTI) (control group). All Danish citizens with osteoarthritis of the thumb carpometacarpal joint referred to the orthopedic department at Copenhagen University Hospital in Herlev/Gentofte will be considered for participation in the trial. The following exclude from participation in the study: Below 40 years of age; cognitive or linguistic impairment; osteoarthritis of other carpal bones; previous surgery in the carpometacarpal joint; patients with rheumatoid arthritis. A total of 64 patients will be included. The primary outcome is the patient reported outcomes questionnaire; Quick-DASH. The secondary outcomes are patient-reported outcomes, functional outcomes, radiographic outcomes, readmission, complications, revisions. The patients are examined before surgery and 3, 6, 12 and 24 months after the operation. The patients are also contacted after 5 and 10 years., conditionsModule conditions: CMC-1 Osteoarthritis, conditions: Trapeziometacarpal Osteoarthritis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 64, type: ESTIMATED, armsInterventionsModule interventions name: Pyrocardan® implant, interventions name: Ligament reconstruction and tendon interposition (LRTI), outcomesModule primaryOutcomes measure: Patient-reported outcome: QuickDASH, secondaryOutcomes measure: Patient-reported outcome, secondaryOutcomes measure: Strength measurements, secondaryOutcomes measure: Radiographs, secondaryOutcomes measure: Return to occupation, eligibilityModule sex: ALL, minimumAge: 40 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Herlev and Gentofte Hospital, status: RECRUITING, city: Hellerup, zip: 2900, country: Denmark, contacts name: Jens Jørgsholm, MD, role: CONTACT, phone: +4551339705, email: Jens.bertel.joergsholm.01@regionh.dk, contacts name: Rasmus Wejnold Jørgensen, MD, PhD, role: CONTACT, phone: +4538673315, email: rasmus.wejnold.joergensen@regionh.dk, geoPoint lat: 55.73204, lon: 12.57093, hasResults: False
protocolSection identificationModule nctId: NCT06290973, orgStudyIdInfo id: PI-23-3017, briefTitle: Quality of Life and Health Perception After Surgery of Varicose Veins, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-01-02, primaryCompletionDateStruct date: 2023-02-28, completionDateStruct date: 2023-11-14, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Hospital Clínico Universitario de Valladolid, class: OTHER, descriptionModule briefSummary: The aim of this study is to analyze changes in health perception and quality of life in patients after surgery for varicose veins using clinical score VCSS and QoL scores SF12 as general health questionary and Veines QoL/Sym as disease specific questionary., conditionsModule conditions: Quality of Life, conditions: Varicose Veins, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 58, type: ACTUAL, armsInterventionsModule interventions name: surgery of varicose veins, outcomesModule primaryOutcomes measure: changes in qol questionarie SF-12 after surgery of varicose veins, primaryOutcomes measure: changes in qol questionarie Veines QoL/Sym after surgery of, secondaryOutcomes measure: changes in VCSS after surgery of varicose veins, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hospital CLínico Universitario de Valladolid, city: Valladolid, country: Spain, geoPoint lat: 41.65518, lon: -4.72372, hasResults: False
protocolSection identificationModule nctId: NCT06290947, orgStudyIdInfo id: BFR-AE-DT2-2023-01, secondaryIdInfos id: IRB 2022/C/20/N, type: OTHER_GRANT, domain: AAUP, briefTitle: BFR Walking for Insulin and Aerobic Improvement in Type 2 Diabetes, acronym: BRAID, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-03-06, primaryCompletionDateStruct date: 2023-12-20, completionDateStruct date: 2024-01-08, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Arab American University (Palestine), class: OTHER, descriptionModule briefSummary: This clinical trial examines the impact of Blood-Flow Restriction Walk Training (BFRw) on insulin sensitivity and aerobic capacity in individuals with Type 2 Diabetes (T2D).The primary objectives of the study are to determine: If Blood-Flow Restriction Walk Training (BFRw) can improve insulin sensitivity in individuals with Type 2 Diabetes (T2D).Whether Blood-Flow Restriction Walk Training (BFRw) enhances aerobic capacity in individuals with Type 2 Diabetes (T2D).Participants in the study are divided into two groups. One group undergoes Blood-Flow Restriction Walk Training (BFRw), and the other serves as a control. Both groups attend three treadmill walking sessions weekly for eight weeks. The BFRw group has a restriction cuff placed around both thighs during their sessions, while the control group participates in the walking sessions without any blood flow restriction.Hemoglobin A1c (HbA1c) levels and maximal oxygen consumption (VO2 max) are monitored as indicators of insulin sensitivity and aerobic capacity, respectively., conditionsModule conditions: Type 2 Diabetes Mellitus, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: This study employs a randomized controlled trial model with a parallel assignment to evaluate the efficacy of Blood-Flow Restriction Walk Training compared to a control condition. Participants are randomly allocated into two groups: one receiving the intervention (BFR walk training) and the other serving as a control (usual walk training). This design allows for the direct comparison of outcomes between the intervention and control groups over the study period., primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, maskingDescription: None (Open Label), enrollmentInfo count: 60, type: ACTUAL, armsInterventionsModule interventions name: BFR Cuffs for Intervention Group, interventions name: Standard Walking Training Program, outcomesModule primaryOutcomes measure: Improvement in Insulin Sensitivity, primaryOutcomes measure: Improvement in Aerobic Capacity, secondaryOutcomes measure: Change in Body Mass Index (BMI), eligibilityModule sex: MALE, minimumAge: 40 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Arab American University - Palestine, city: Jenin, zip: P.O Box 24, country: Palestinian Territory, occupied, geoPoint lat: 32.45943, lon: 35.30086, hasResults: False
protocolSection identificationModule nctId: NCT06290921, orgStudyIdInfo id: 3472, briefTitle: Ovulation Triggering 2 vs 3 Follicles, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-02-22, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2025-02-20, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Clinique Ovo, class: INDUSTRY, descriptionModule briefSummary: Poor responders in in-vitro fertilization (IVF) cycles represent a major challenge for fertility specialists. Although poor responders tend to have sub-optimal fertility treatment outcomes, many of these patients wish to attempt at least one IVF cycle. Traditionally, IVF cycles producing less than 3 to 4 mature follicles (measuring at least 14 mm) have either been cancelled or converted to intra-uterine insemination (IUI) due to the low pregnancy rates associated with these cycles. The minimal number of follicles required to proceed with egg collection is based on clinical experience, having been determined by weighing the probability of implantation and pregnancy versus the risk of not obtaining quality oocytes or reaching embryo transfer when fewer mature follicles are present. This retrospective quality control study aims to compare pregnancy rates in IVF cycles producing 3 follicles measuring 14 mm and more on trigger day, versus 2 or fewer follicles., conditionsModule conditions: Infertility, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 400, type: ESTIMATED, armsInterventionsModule interventions name: Ovulation triggering, outcomesModule primaryOutcomes measure: Clinical Pregnancy Rate, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 42 Years, stdAges: ADULT, contactsLocationsModule locations facility: Clinique Ovo, city: Montréal, state: Quebec, zip: H4P 2S4, country: Canada, geoPoint lat: 45.50884, lon: -73.58781, hasResults: False
protocolSection identificationModule nctId: NCT06290908, orgStudyIdInfo id: TF2018-001-01, briefTitle: RPE-P/TLIF for Lumbar Spinal Stenosis With Instability, statusModule overallStatus: COMPLETED, startDateStruct date: 2018-09-04, primaryCompletionDateStruct date: 2022-04-30, completionDateStruct date: 2024-02-01, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Wen-xi Sun, class: OTHER, collaborators name: Guangdong Provincial Hospital of Traditional Chinese Medicine, descriptionModule briefSummary: Objective To analyze the effectiveness and safety of robot-assisted percutaneous endoscopic posterior/transforaminal lumbar interbody fusion (RPE-P/TLIF) in the treatment of lumbar spinal stenosis with instability. Methods A single-center prospective study from September 2018 to April 2022, patients with lumbar spinal stenosis and instability who met the inclusion and exclusion criteria were treated with RPE-P/TLIF. Pain visual analog scale (VAS) was used to evaluate the degree of low back pain and lower limb pain before operation, 1 month, 6 months, 1 year after operation and at the final follow-up, and the Oswestry disability index (ODI) was used to evaluate the degree of lumbar spinal function. At the last follow-up, MacNab criteria were used to evaluate the clinical efficacy. Imaging evaluation included the measurement of intervertebral space height, lumbar physiological curvature, fusion rate and pedicle screw accuracy by preoperative and lateral X-ray films., conditionsModule conditions: Spinal Stenosis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 26, type: ACTUAL, armsInterventionsModule interventions name: RPE-P/TLIF, outcomesModule primaryOutcomes measure: Pain visual analog scale (VAS), secondaryOutcomes measure: Oswestry disability index (ODI), secondaryOutcomes measure: MacNab criteria, secondaryOutcomes measure: intervertebral space height, secondaryOutcomes measure: lumbar physiological curvature, secondaryOutcomes measure: fusion rate, secondaryOutcomes measure: pedicle screw accuracy, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Guangdong Provincial Hospital of Traditional Chinese Medicine, city: Guangzhou, country: China, geoPoint lat: 23.11667, lon: 113.25, hasResults: False
protocolSection identificationModule nctId: NCT06290895, orgStudyIdInfo id: 3465, briefTitle: Artificial Oocyte Activation, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-02-22, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2025-02-19, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Clinique Ovo, class: INDUSTRY, descriptionModule briefSummary: Studies reported that calcium signal deficiency or insufficiency during oocyte activation are related with embryo arrest and blastocyst quality. The utilization of Artificial Oocyte Activation (AOA) is safe and does not increase birth defects, cognition, language and motor skills. AOA is the first line of treatment in patients with globozoospermia (round headed spermatozoa). Poor responders in in-vitro fertilization (IVF) cycles represent a major challenge for fertility specialists and comprises about 10-15% of patients undergoing controlled ovarian hyperstimulation. The absence of synergy between the oocyte and sperm leads to a negative impact on oocyte activation. The European Society of Human and REproduction (ESHRE) recommends AOA in cases with failed fertilization/ low fertilization., conditionsModule conditions: Infertility, conditions: Ovarian Insufficiency, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 54, type: ACTUAL, armsInterventionsModule interventions name: women having had a second IVF cycle with AOA, outcomesModule primaryOutcomes measure: Blastocyst rate, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 42 Years, stdAges: ADULT, contactsLocationsModule locations facility: Clinique Ovo, city: Montréal, state: Quebec, zip: H4P 2S4, country: Canada, geoPoint lat: 45.50884, lon: -73.58781, hasResults: False
protocolSection identificationModule nctId: NCT06290869, orgStudyIdInfo id: STUDY00006070, briefTitle: Tobacco Education and Lung Health Study (TEAL), acronym: TEAL, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-22, primaryCompletionDateStruct date: 2026-02, completionDateStruct date: 2026-04, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Georgetown University, class: OTHER, descriptionModule briefSummary: Primary Objective To compare two smoking cessation interventions among individuals undergoing lung cancer screening. Primary outcomes are: 3-month self-reported abstinence from cigarettes and 6-month self-reported and bioverified abstinence from cigarettes.Secondary Objectives 1) To evaluate reach and engagement overall and by subgroup (e.g., race and ethnicity, underinsured, readiness to quit). 2) To conduct an economic analysis to evaluate intervention costs from the health system perspective., conditionsModule conditions: Smoking Cessation, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 1188, type: ESTIMATED, armsInterventionsModule interventions name: Phone-based Tobacco Treatment, Nicotine Replacement, and Stepped Care Intervention, interventions name: E-Referral to the Tobacco Quitline, outcomesModule primaryOutcomes measure: Biochemically verified smoking abstinence- MHS vs. QL-E arms, primaryOutcomes measure: Biochemically verified smoking abstinence--continued MHS arm vs Stepped Care, secondaryOutcomes measure: self-reported smoking status, secondaryOutcomes measure: cigarettes per day, secondaryOutcomes measure: readiness to quit, secondaryOutcomes measure: Patient reach and patient engagement, secondaryOutcomes measure: Costs per arm from the health system perspective, eligibilityModule sex: ALL, minimumAge: 50 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Georgetown University Medical Center, status: RECRUITING, city: Washington, state: District of Columbia, zip: 20007, country: United States, contacts name: Kathryn L Taylor, PhD, role: CONTACT, phone: 202-215-9402, email: taylorkl@georgetown.edu, geoPoint lat: 38.89511, lon: -77.03637, hasResults: False
protocolSection identificationModule nctId: NCT06290856, orgStudyIdInfo id: 651397, briefTitle: Clinical Utility of Selected Circulating Tumor DNA Assays in Patients With Advanced Malignancy, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-15, primaryCompletionDateStruct date: 2025-12-15, completionDateStruct date: 2025-12-15, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-07, sponsorCollaboratorsModule leadSponsor name: Oslo University Hospital, class: OTHER, descriptionModule briefSummary: Circulating tumor DNA assays are becoming relevant for routine diagnostics, but many related aspects are yet unresolved. With this project, the investigators aim to develop pragmatic molecular diagnostic pathways of liquid biopsies relevant in advanced gastrointestinal malignancies with focus on clinical utility and sensible use of resources. They want to evaluate the ctDNA assays on a fully automated "low-cost" multiplex platform which is already implemented in routine molecular diagnostics of solid biopsies. The project will evaluate to what extent these ctDNA assays are relevant for clinical decision-making., conditionsModule conditions: Metastatic Colorectal Cancer, conditions: Pancreas Adenocarcinoma, conditions: Cholangiocarcinoma, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Multiplex PCR-test for circulating tumor DNA, outcomesModule primaryOutcomes measure: Clinical validity of ctDNA tests, secondaryOutcomes measure: Resources needed for ctDNA assays in routine diagnostics, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Oslo university Hospital, status: RECRUITING, city: Oslo, country: Norway, contacts name: Ragnhild Nome, MD, PhD, role: CONTACT, geoPoint lat: 59.91273, lon: 10.74609, hasResults: False
protocolSection identificationModule nctId: NCT06290843, orgStudyIdInfo id: AWFiS/2024_1_PE, briefTitle: Analysis of Body Balance Parameters in Children With Idiopathic Scoliosis, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-05, primaryCompletionDateStruct date: 2024-05-30, completionDateStruct date: 2024-05-30, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Gdansk University of Physical Education and Sport, class: OTHER, descriptionModule briefSummary: The aim of the study is to compare body balance parameters assessed using the AMTI dynamometric platform in children with idiopathic scoliosis (with and without Schroth therapy) compared to control group., conditionsModule conditions: Idiopathic Scoliosis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Schroth method, outcomesModule primaryOutcomes measure: Analysis of body balance on the AMTI force platform, primaryOutcomes measure: Analysis of body balance on the AMTI force platform, primaryOutcomes measure: Analysis of body balance on the AMTI force platform, primaryOutcomes measure: Analysis of body balance on the AMTI force platform, primaryOutcomes measure: Photographic analysis of body posture, primaryOutcomes measure: Analysis of x-ray in the frontal plane, primaryOutcomes measure: Analysis of x-ray in the frontal plane, primaryOutcomes measure: Analysis of x-ray in the frontal plane, primaryOutcomes measure: Analysis of x-ray in the frontal plane, primaryOutcomes measure: Analysis of x-ray in the sagittal plane, primaryOutcomes measure: Analysis of x-ray in the sagittal plane, eligibilityModule sex: FEMALE, minimumAge: 10 Years, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Gdansk University of Physical Education and Sport, city: Gdańsk, state: Pomorskie, zip: 80-336, country: Poland, geoPoint lat: 54.35205, lon: 18.64637, hasResults: False
protocolSection identificationModule nctId: NCT06290830, orgStudyIdInfo id: OMUŞükranBaşgöl01, briefTitle: Abdominal Massage and Kegel Exercises on Constipation and Quality of Life in Female Students, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-15, primaryCompletionDateStruct date: 2024-05-31, completionDateStruct date: 2024-06-01, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Ondokuz Mayıs University, class: OTHER, descriptionModule briefSummary: In this prospective, randomized controlled study, n=140 female students with functional constipation studying at two universities Faculty of Health Sciences and meeting the Rome-IV Diagnostic Criteria for Constipation will be included in the study. Between 15.03.2024 and 31.05.2024, n=140 (35=control group, 35=kegel exercise group, 35=abdominal exercise group, 35=abdominal and kegel exercise group) volunteered to participate in the study. Female students with functional constipation will be randomly divided into four groups as intervention and control groups. Personal Information Form", "Bristol Stool Scale", "Constipation Severity Scale", and "Patient Assessment of Constipation Quality of Life Questionnaire" will be used in this study. The scales will be used in the research two times: pre and post-test (scales were reassessed at the end of the study after the exercise intervention). Descriptive statistics, Pearson, and Spearman's correlation analyses will be used in the analysis of research data., conditionsModule conditions: Functional Constipation, conditions: Constipation, conditions: Quality of Life, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 140, type: ESTIMATED, armsInterventionsModule interventions name: Abdominal massage group, interventions name: Kegel Exercises group, interventions name: Both abdominal massage and kegel exercises to gether, outcomesModule primaryOutcomes measure: Constipation severity change, primaryOutcomes measure: Quality of Life change, primaryOutcomes measure: Bristol stool form score change, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 35 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False