hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06268860, orgStudyIdInfo id: 20220015, briefTitle: A Study to Assess Bioavailability of Rocatinlimab (AMG 451) Vial and Prefilled Syringe in Healthy Participants, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-15, primaryCompletionDateStruct date: 2024-08-29, completionDateStruct date: 2024-08-29, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-04-12, sponsorCollaboratorsModule leadSponsor name: Amgen, class: INDUSTRY, descriptionModule briefSummary: The primary objective of the study is to evaluate the pharmacokinetics (PK) of rocatinlimab given as a single subcutaneous (SC) dose in a vial compared to a prefilled syringe in healthy participants., conditionsModule conditions: Atopic Dermatitis, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 230, type: ESTIMATED, armsInterventionsModule interventions name: Rocatinlimab vial injection, interventions name: Rocatinlimab prefilled syringe, outcomesModule primaryOutcomes measure: Maximum Observed Serum Concentration (Cmax) of Rocatinlimab, primaryOutcomes measure: Area Under the Serum Concentration-time Curve (AUC) From Time Zero to Time of Last Quantifiable Concentration (AUClast) of Rocatinlimab, primaryOutcomes measure: AUC From Time Zero to Infinity (AUCinf) of Rocatinlimab, secondaryOutcomes measure: Number of Participants Experiencing Treatment-emergent Adverse Events (TEAE), secondaryOutcomes measure: Number of Participants Experiencing Serious Adverse Events (SAE), secondaryOutcomes measure: Number of Participants Positive to Anti-rocatinlimab Antibody, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Fortrea Clinical Research Unit - Daytona Beach, status: RECRUITING, city: Daytona Beach, state: Florida, zip: 32117-5116, country: United States, geoPoint lat: 29.21081, lon: -81.02283, locations facility: Fortrea Clinical Research Unit - Dallas, status: RECRUITING, city: Dallas, state: Texas, zip: 75247-4968, country: United States, geoPoint lat: 32.78306, lon: -96.80667, locations facility: Fortrea Clinical Research Unit Limited - Leeds, status: RECRUITING, city: Leeds, state: LDS, zip: LS2 9LH, country: United Kingdom, geoPoint lat: 53.79648, lon: -1.54785, hasResults: False
protocolSection identificationModule nctId: NCT06268847, orgStudyIdInfo id: DERMATIDYSS, briefTitle: Efficacy of Marine By-product Hydrolysate on the Reduction of Atopic Dermatitis Symptoms, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-09, primaryCompletionDateStruct date: 2024-06-18, completionDateStruct date: 2024-06-18, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: Abyss Ingredients, class: INDUSTRY, collaborators name: Eurofins, descriptionModule briefSummary: This interventional, double-blind, randomized, placebo-controlled study aims to evaluate the effect of a marine by-product hydrolysate supplementation on the reduction of atopic dermatitis symptoms., conditionsModule conditions: Atopic Dermatitis, conditions: Eczema, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 108, type: ESTIMATED, armsInterventionsModule interventions name: Placebo, interventions name: ACT01, interventions name: ACT02, outcomesModule primaryOutcomes measure: SCORAD (SCORing Atopic Dermatitis), secondaryOutcomes measure: EASI (Eczema Area and Severity Index), secondaryOutcomes measure: Investigator Global Assessment scale, secondaryOutcomes measure: Corneometer, secondaryOutcomes measure: Tewameter, secondaryOutcomes measure: Quality of Life Index - Perceived Stress, secondaryOutcomes measure: Participant's Satisfaction, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule locations facility: Eurofins, status: RECRUITING, city: Barcelona, zip: 08013, country: Spain, contacts name: Jessica Zumaquero, role: CONTACT, phone: +34 932 85 14 46, phoneExt: 1110, email: JessicaZumaquero@eurofins.com, geoPoint lat: 41.38879, lon: 2.15899, hasResults: False
protocolSection identificationModule nctId: NCT06268834, orgStudyIdInfo id: ZonulinPPI, briefTitle: Is Long-Term Proton Pump Inhibitor Use a Cause of Leaky Gut Syndrome, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-10-04, primaryCompletionDateStruct date: 2023-12-31, completionDateStruct date: 2023-12-31, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, class: OTHER, descriptionModule briefSummary: Our study aims to investigate the effect of bacterial overgrowth induced by long-term PPI use on zonulin levels., conditionsModule conditions: Proton Pump Inhibitor Adverse Reaction, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Parallel Assignment, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 75, type: ACTUAL, armsInterventionsModule interventions name: Blood for zonulin level was drawn from the group., outcomesModule primaryOutcomes measure: Zonulin levels in long-term proton pump inhibitor users, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, city: Ankara, country: Turkey, geoPoint lat: 39.91987, lon: 32.85427, hasResults: False
protocolSection identificationModule nctId: NCT06268821, orgStudyIdInfo id: ADC-UK-PMS-23059, briefTitle: Effect on HbA1c of the Initiation of CGM in Adults With Type 2 Diabetes Treated With Basal Insulin in Finland, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-02, primaryCompletionDateStruct date: 2025-01, completionDateStruct date: 2025-01, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: Abbott Diabetes Care, class: INDUSTRY, descriptionModule briefSummary: The goal of this clinical study is to determine the impact of starting the use of the FreeStyle Libre 2 glucose monitoring system, over a three month period, on HbA1c in adults with type 2 diabetes treated with a basal insulin regimen., conditionsModule conditions: Type 2 Diabetes Treated With Insulin, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 82, type: ESTIMATED, armsInterventionsModule interventions name: FreeStyle Libre 2 Flash Glucose Monitoring System, outcomesModule primaryOutcomes measure: HbA1c, secondaryOutcomes measure: Time in range (TIR), secondaryOutcomes measure: Time above range (TAR), secondaryOutcomes measure: Time below range (TBR), secondaryOutcomes measure: Frequency of hypoglycaemia events, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Pihlajalinna Jämsä, Välikatu 1,, city: Jämsä, zip: 42100, country: Finland, contacts name: Henri Honka, MD, PhD, role: CONTACT, geoPoint lat: 61.8642, lon: 25.19002, locations facility: Pihlajalinna Koskiklinikka, Hatanpäänvaltatie 1,, city: Tampere, zip: 33100, country: Finland, contacts name: Elina Pimiä, MD, role: CONTACT, geoPoint lat: 61.49911, lon: 23.78712, hasResults: False
protocolSection identificationModule nctId: NCT06268808, orgStudyIdInfo id: ADC-UK-PMS-23058, briefTitle: Initiation of Continuous Glucose Monitoring in Adults With Type 2 Diabetes Treated With Basal Insulin, in Italy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-02, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: Abbott Diabetes Care, class: INDUSTRY, descriptionModule briefSummary: The goal of this clinical study is to determine the impact of starting the use of the FreeStyle Libre 2 glucose monitoring system, over a three month period, on HbA1c in adults with type 2 diabetes treated with a basal insulin regimen., conditionsModule conditions: Type 2 Diabetes Treated With Insulin, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 82, type: ESTIMATED, armsInterventionsModule interventions name: FreeStyle Libre 2 Flash Glucose Monitoring System, outcomesModule primaryOutcomes measure: HbA1c, secondaryOutcomes measure: Time in range (TIR), secondaryOutcomes measure: Time above range (TAR), secondaryOutcomes measure: Time below range (TBR), secondaryOutcomes measure: Frequency of hypoglycaemia events, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari, city: Bari, country: Italy, contacts name: Francesco Giorgino, role: CONTACT, geoPoint lat: 41.11148, lon: 16.8554, locations facility: Università degli Studi di Catania, Ospedale Garibaldi-Nesima, U.O. Endocrinologia, city: Catania, country: Italy, contacts name: Lucia Frittitta, role: CONTACT, geoPoint lat: 37.49223, lon: 15.07041, locations facility: Università degli Studi di Catania, Ospedale Garibaldi-Nesima, U.O.C. Medicina Interna, city: Catania, country: Italy, contacts name: Salvatore Piro, role: CONTACT, geoPoint lat: 37.49223, lon: 15.07041, locations facility: Azienda Ospedaliera - Università di Padova, city: Padova, country: Italy, contacts name: Gian Paolo Fadini, role: CONTACT, geoPoint lat: 45.40797, lon: 11.88586, locations facility: Azienda Ospedaliero-Universitaria di Parma, city: Parma, country: Italy, contacts name: Riccardo Bonadonna, role: CONTACT, geoPoint lat: 44.79935, lon: 10.32618, locations facility: La Sapienza Università di Roma, AOU Policlinico Umberto I, city: Rome, country: Italy, contacts name: Raffaella Buzzetti, role: CONTACT, geoPoint lat: 41.89193, lon: 12.51133, hasResults: False
protocolSection identificationModule nctId: NCT06268795, orgStudyIdInfo id: BASE, briefTitle: A Diagnostic Test Accuracy Study Comparing Biopsy to Aspiration in Shoulder and Elbow Arthroplasty Revision Surgery (BASE Study), statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-20, primaryCompletionDateStruct date: 2028-09-01, completionDateStruct date: 2028-09-01, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Wrightington, Wigan and Leigh NHS Foundation Trust, class: OTHER, descriptionModule briefSummary: The aim of this study is to compare the diagnostic accuracy of percutaneous aspiration against open biopsy, using microbiological and histological methods, for the detection of shoulder and elbow periprosthetic joint infection (PJI). This is to establish the utility of pre-operative joint aspiration in the treatment pathway for shoulder and elbow PJI., conditionsModule conditions: Periprosthetic Joint Infection, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 244, type: ESTIMATED, outcomesModule primaryOutcomes measure: Comparison of diagnostic accuracy, secondaryOutcomes measure: Culture analysis, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Wrightington Wigan & Leigh Teaching Hospitals NHS Foundation Trust, status: RECRUITING, city: Wigan, state: Lancashire, zip: WN6 9EP, country: United Kingdom, contacts name: Zaid Z Hamoodi, role: CONTACT, email: zaid.hamoodi@nhs.net, geoPoint lat: 53.54295, lon: -2.63705, hasResults: False
protocolSection identificationModule nctId: NCT06268782, orgStudyIdInfo id: 1204202118, briefTitle: The Effectiveness of an Online Exercise Program on Well-being of Postpartum Women, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-09-21, primaryCompletionDateStruct date: 2023-01-24, completionDateStruct date: 2023-09-19, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-02-22, sponsorCollaboratorsModule leadSponsor name: University of Turku, class: OTHER, collaborators name: Finnish Cultural Foundation, descriptionModule briefSummary: The aim of this quasi-experimental study was to assess the effectiveness of a 6-week online exercise program on self-assessed quality of life (QoL), physical activity (PA), and dysfunctions of pelvic floor muscles of postpartum women immediately and 6 months after the online intervention. The data were collected with e-questionnaires. The data collection started in September 2021 and ended in September 2023., conditionsModule conditions: Quality of Life, conditions: Physical Activity, conditions: Urinary Incontinence, conditions: Pelvic Organ Prolapse, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 308, type: ACTUAL, armsInterventionsModule interventions name: Rehabilitate your core, outcomesModule primaryOutcomes measure: Quality of Life, secondaryOutcomes measure: Physical activity, secondaryOutcomes measure: Urinary incontinence, secondaryOutcomes measure: Pelvic organ prolapse, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Department of Nursing Science, Faculty of Medicine, University of Turku, city: Turku, zip: 20014, country: Finland, geoPoint lat: 60.45148, lon: 22.26869, hasResults: False
protocolSection identificationModule nctId: NCT06268756, orgStudyIdInfo id: 2023_RIPH_020_RESANXIEST, briefTitle: Fear of Other's Judgment, Self-esteem and Use of Social Networks Among Students, acronym: RESANXIEST, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-07, primaryCompletionDateStruct date: 2024-04-07, completionDateStruct date: 2024-06-07, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: Université de Reims Champagne-Ardenne, class: OTHER, descriptionModule briefSummary: Fear of being judged negatively by others can lead to avoidance of social situations or even social isolation. If the intensity of this fear is excessive and results in significant impairment of functioning or significant suffering, the subject may suffer from social anxiety.The considerable growth of social networks in a decade has led to the emergence of new behaviors among young people. Individuals spend on average 2 hours and 27 minutes per day with differences in usage: time spent, social network used, function sought. The use of these networks may be reasonable and moderate but may also be excessive and abusive (Amnon, 2014). Some authors even talk about addiction or dependence on social networks (Perales and Billieux, 2020) even if the existence of this disorder is not consensus.People who fear being judged negatively by others may be more at risk of misuse of social networks. Indeed, the use of social networks would compensate for their existing problems (Kardefelt-Winther, 2014) and would thus be a new emotional management strategy. It would also reduce dreaded social situations such as face-to-face exchanges (Weidman and Rodebaugh, 2012; Yen and Ko, 2012). Self-esteem is defined as a subjective judgment of oneself in relation to one's values and vision of the real and ideal self (Rosenberg. 1979). The greater the gap between the vision of the real self and the ideal self, the lower the self-esteem., conditionsModule conditions: Self-esteem, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 500, type: ESTIMATED, armsInterventionsModule interventions name: Data collection, outcomesModule primaryOutcomes measure: Rosenberg Self-esteem Scale, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ufr Medecine Urca, status: RECRUITING, city: Reims, zip: 51100, country: France, contacts name: Coralie Barbe, role: CONTACT, phone: 326913665, phoneExt: +33, email: coralie.barbe1@univ-reims.fr, geoPoint lat: 49.25, lon: 4.03333, locations facility: Université de Reims Champagne Ardenne, status: RECRUITING, city: Reims, zip: 51100, country: France, contacts name: CURRS CURRS, role: CONTACT, phone: 0326918822, email: currs@univ-reims.fr, geoPoint lat: 49.25, lon: 4.03333, hasResults: False
protocolSection identificationModule nctId: NCT06268743, orgStudyIdInfo id: 2023-114, briefTitle: Effects of a Combined Exercise Intervention on the Gut Microbiome of People With Type 2 Diabetes, acronym: GUTFIT, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-02, primaryCompletionDateStruct date: 2025-08, completionDateStruct date: 2026-08, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: University of New Brunswick, class: OTHER, collaborators name: Laval University, descriptionModule briefSummary: The goal of this experimental trial is to learn about the changes in bacterial diversity in individuals with type 2 diabetes who perform endurance and strength training at different intensities.Participants with type 2 diabetes will be randomly assigned to 16 weeks of either moderate-intensity endurance and strength training or high-intensity endurance and strength training.Researchers will compare the moderate-intensity and high-intensity exercise groups for differences in glycemia and bacterial diversity., conditionsModule conditions: Type 2 Diabetes, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Parallel group, single blinded, randomized trial, primaryPurpose: PREVENTION, maskingInfo masking: SINGLE, whoMasked: INVESTIGATOR, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: High intensity, interventions name: Moderate intensity, outcomesModule primaryOutcomes measure: Glycemic control through glycated hemoglobin, primaryOutcomes measure: Gut microbiome diversity through 16S ribosomal RNA genes, eligibilityModule sex: ALL, minimumAge: 19 Years, maximumAge: 64 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06268704, orgStudyIdInfo id: UNM HRRC #23-503, briefTitle: Particulate vs. Non-Particulate Steroid for Sacroiliac Joint Injection, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-27, primaryCompletionDateStruct date: 2025-01-01, completionDateStruct date: 2025-05-01, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: University of New Mexico, class: OTHER, descriptionModule briefSummary: This study will compare two different corticosteroids (dexamethasone and methylprednisolone) for use in sacroiliac joint injections to treat SI joint pain., conditionsModule conditions: Sacroiliac Joint Dysfunction, conditions: Sacro-Iliac Spondylosis, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 230, type: ESTIMATED, armsInterventionsModule interventions name: Dexamethasone, interventions name: Methylprednisolone, interventions name: 2% Lidocaine HCl Injection, outcomesModule primaryOutcomes measure: Pain using Numeric Pain Rating Score, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 99 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of New Mexico Hospital, status: RECRUITING, city: Albuquerque, state: New Mexico, zip: 87131, country: United States, contacts name: Mark W Shilling, BS, role: CONTACT, phone: 505-925-7599, email: mwshilling@salud.unm.edu, geoPoint lat: 35.08449, lon: -106.65114, hasResults: False
protocolSection identificationModule nctId: NCT06268678, orgStudyIdInfo id: 4539513, briefTitle: The Effect of Menstrual Cycle Phase on Muscle Protein Synthesis, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-12-08, primaryCompletionDateStruct date: 2025-01-30, completionDateStruct date: 2025-01-30, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: University of Exeter, class: OTHER, collaborators name: Pvolve, descriptionModule briefSummary: The combination of dietary protein ingestion and resistance exercise are essential to increase muscle protein synthesis. The vast majority of studies assessing protein intake following resistance exercise in young adults has been conducted exclusively in men or in studies where both men and women are assessed. The increase in muscle mass is thought to be impacted by sex hormones that fluctuate across different phases of the menstrual cycle. However, the effect of menstrual cycle phase on muscle protein synthesis following exercise is not known., conditionsModule conditions: Menstrual Cycle Phase, conditions: Muscle Protein Synthesis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: Randomised cross-over design., primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 15, type: ESTIMATED, armsInterventionsModule interventions name: Phase of the menstrual cycle, outcomesModule primaryOutcomes measure: Muscle protein synthesis, secondaryOutcomes measure: Plasma amino acid kinetics, secondaryOutcomes measure: Serum insulin concentrations, secondaryOutcomes measure: Sex hormone concentrations, secondaryOutcomes measure: Energy expenditure, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: University of Exeter, status: RECRUITING, city: Exeter, state: Devon, zip: EX1 2LT, country: United Kingdom, contacts name: Marianna Apicella, role: CONTACT, geoPoint lat: 50.7236, lon: -3.52751, hasResults: False