protocolSection identificationModule nctId: NCT06330844, orgStudyIdInfo id: RBSEF-MCI-CCT, briefTitle: Race-Based Stress and Cognitive Training for MCI, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-15, primaryCompletionDateStruct date: 2026-09-15, completionDateStruct date: 2027-03-15, studyFirstPostDateStruct date: 2024-03-26, lastUpdatePostDateStruct date: 2024-03-26, sponsorCollaboratorsModule leadSponsor name: Rosalind Franklin University of Medicine and Science, class: OTHER, descriptionModule briefSummary: This a two phase project that aims to pilot a new adaptation (Phase 1) of Motivationally Enhanced Compensatory Cognitive Training for Mild Cognitive Impairment (ME-CCT; an originally VA-based cognitive rehabilitation manualized intervention for older adults with MCI, with a focus on the impact of stress on cognitive functioning; that integrates components from the Race Based Stress and Empowerment (RBSE) group for an increased focus on race-based stress and discrimination for racial minority older adults (i.e., RBSEF-CCT-MCI). In a pilot open trial, 75-150 participants will receive group-based intervention for 8 weeks, with 8-10 participants per group.Following the pilot study, the investigators will complete a randomized controlled trial (RCT) (Phase 2) to compare the efficacy of the RBSEF-CCT-MCI with the ME-CCT. In the RCT, 75-150 participants will be randomized into either 1) The active control group, who will complete the original, ME-CCT training program, or 2) The experimental group, who will complete the newly developed RBSE-CCT-MCI. Both research groups will complete the interventions for 8 weeks, with 8-10 participants per group.Hypothesis: Participation in this newly developed/updated intervention (i.e., RBSEF-CCT-MCI) will result in improvements in both (a) subjective and (b) objective cognitive functioning, and (c) self-reported mental health symptoms., conditionsModule conditions: Mild Cognitive Impairment, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Two groups assignment - One group will complete the original ME-CCT training program. The other group will complete the newly developed RBSE-CCT-MCI., primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 9, type: ESTIMATED, armsInterventionsModule interventions name: Race Based Stress and Empowerment Focused Compensatory Cognitive Training for Mild Cognitive Impairment (RBSEF-CCT-MCI), interventions name: Motivationally Enhanced Compensatory Cognitive Training for Mild Cognitive Impairment (ME-CCT), outcomesModule primaryOutcomes measure: Verbal learning and memory, primaryOutcomes measure: Basic auditory attention and working memory, primaryOutcomes measure: Psychomotor processing speed, primaryOutcomes measure: Psychomotor processing speed; executive functioning, primaryOutcomes measure: Self-report of prospective and retrospective memory, primaryOutcomes measure: Self-report of cognitive concerns, primaryOutcomes measure: The Patient Health Questionnaire-9, primaryOutcomes measure: Self-report symptoms of anxiety, primaryOutcomes measure: Self-reported daily functioning, primaryOutcomes measure: The Racial Microaggressions Scale, primaryOutcomes measure: The Trauma Symptoms of Discrimination Scale, eligibilityModule sex: ALL, minimumAge: 65 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Rosalind Franklin University of Medicine and Science, city: Chicago, state: Illinois, zip: 60064, country: United States, contacts name: Rachael Ellison, PhD, role: CONTACT, contacts name: Rachael Ellison, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 41.85003, lon: -87.65005, hasResults: False