hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06381284, orgStudyIdInfo id: MG-001, briefTitle: Feasibility of Engaging and Capturing Undiagnosed Myasthenia Gravis Participants Through a Social Media Campaign Paired With a Self-moderated Assessment, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-28, primaryCompletionDateStruct date: 2024-05-27, completionDateStruct date: 2025-05-27, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-26, sponsorCollaboratorsModule leadSponsor name: ZS Associates, class: INDUSTRY, collaborators name: University of California, San Francisco, descriptionModule briefSummary: This is a fully remote, site-less, prospective, observational study enrolling adults in the United States (excluding U.S. territories) with undiagnosed neuromuscular symptoms. The main study objective is to evaluate the feasibility of a social media recruitment campaign tied to a participant reported symptom survey and self-administered physical assessment tool to influence undiagnosed participants to seek care for suspected Myasthenia Gravis (MG)., conditionsModule conditions: Myasthenia Gravis, conditions: Neuromuscular Manifestations, conditions: Neuromuscular Diseases, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 1000, type: ESTIMATED, armsInterventionsModule interventions name: Social media recruitment, interventions name: Self-Assessment, interventions name: Follow-up, outcomesModule primaryOutcomes measure: Social media recruitment feasibility, secondaryOutcomes measure: MG Exercise Assessment Tool validity, otherOutcomes measure: Time to diagnosis, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: ZS Associates, status: RECRUITING, city: Evanston, state: Illinois, zip: 60201, country: United States, contacts name: Ananda V Pandurangadu, MD, role: CONTACT, phone: 1-847-448-1001, email: support@unearthrootcause.com, contacts name: Ananda Vishnu Pandurangadu, MD, role: PRINCIPAL_INVESTIGATOR, contacts name: Pritikanta Paul, MD, role: SUB_INVESTIGATOR, geoPoint lat: 42.04114, lon: -87.69006, hasResults: False
protocolSection identificationModule nctId: NCT06381271, orgStudyIdInfo id: TRUST TAVR Registry, briefTitle: Transcatheter Aortic Valve Replacement for Pure Severe Aortic Valve Regurgitation, statusModule overallStatus: RECRUITING, startDateStruct date: 2018-10-30, primaryCompletionDateStruct date: 2034-10, completionDateStruct date: 2034-10, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Xijing Hospital, class: OTHER, descriptionModule briefSummary: The purpose of this multicenter, prospective and observational registry is to evaluate the safety and efficacy of TAVR for treatment of pure severe aortic valve regurgitation. Baseline characteristics, procedural and clinical data will be collected, conditionsModule conditions: Aortic Valve Regurgitation, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 500, type: ESTIMATED, armsInterventionsModule interventions name: Transcatheter aortic valve replacement, outcomesModule primaryOutcomes measure: Combined clinical efficacy outcomes, secondaryOutcomes measure: Combined early safety and clinical efficacy outcomes, secondaryOutcomes measure: Rate of technical success, secondaryOutcomes measure: Rate of device success, secondaryOutcomes measure: Combined clinical efficacy outcomes, secondaryOutcomes measure: Rate of all-cause mortality, secondaryOutcomes measure: Valve-related long-term clinical efficacy, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Xijing Hospital, status: RECRUITING, city: Xi'an, state: Shannxi, zip: 710032, country: China, contacts name: Rutao Wang, M.D., Ph.D., role: CONTACT, phone: +86-15091095796, email: rutaowang@qq.com, contacts name: Ruining Zhang, BSc, role: CONTACT, phone: +86-15802990370, email: ruining-zhang@qq.com, contacts name: Ling Tao, M.D., Ph.D., role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 34.25833, lon: 108.92861, hasResults: False
protocolSection identificationModule nctId: NCT06381258, orgStudyIdInfo id: SDF, briefTitle: Fetal Cardiac Function, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2024-10, completionDateStruct date: 2024-11, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: The aim of our study is to evaluate the effect of PE and FGR on fetal cardiac function. Pregnancies with preeclampsia and FGR, and preeclampsia with normal fetal growth are evaluated by echocardiography and compared with uncomplicated pregnancies., conditionsModule conditions: Fetal Growth Retardation, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 32, type: ESTIMATED, armsInterventionsModule interventions name: Ultrasound, outcomesModule primaryOutcomes measure: Cardiac systolic function, secondaryOutcomes measure: Cardiac diastolic function, eligibilityModule sex: FEMALE, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06381232, orgStudyIdInfo id: VIOME-001, briefTitle: Collection and Analyses of Physiological, Physical, and Molecular Data From a Diverse Population, statusModule overallStatus: RECRUITING, startDateStruct date: 2018-07-23, primaryCompletionDateStruct date: 2028-07-23, completionDateStruct date: 2028-07-23, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Viome, class: INDUSTRY, descriptionModule briefSummary: The purpose of the study is to collect and analyze physiological, physical, and molecular data from a diverse population to increase our understanding of how such parameters are associated with health and disease., conditionsModule conditions: General Health, conditions: Wellness, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 20000, type: ESTIMATED, armsInterventionsModule interventions name: No Intervention, outcomesModule primaryOutcomes measure: Molecular Determinants of Health and Disease, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Viome Life Sciences, status: RECRUITING, city: Bothell, state: Washington, zip: 98011, country: United States, contacts name: Momchilo Vuyisich, role: CONTACT, phone: 425-300-6933, email: studies@viome.com, geoPoint lat: 47.76232, lon: -122.2054, hasResults: False
protocolSection identificationModule nctId: NCT06381219, orgStudyIdInfo id: s67001, briefTitle: Pediatric Eosinophilic Esophagitis (pedEoE): Effect of Allergen Heat Denaturation on EoE Remission: a Pilot Trial, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-12-19, primaryCompletionDateStruct date: 2026-12-31, completionDateStruct date: 2028-12-31, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Universitaire Ziekenhuizen KU Leuven, class: OTHER, descriptionModule briefSummary: The objective of the study is to study whether the introduction of heated food products (more specifically heated hen's egg and/or cow's milk) in children with EoE would be possible without re-occurrence of the eosinophilic inflammation, while the intake of less heated products might cause disease recidive. Moreover, we would like to study whether the gradual re-introduction of less heated products after the most heated form is tolerated, could lead to tolerance induction in EoE., conditionsModule conditions: Eosinophilic Esophagitis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 36, type: ESTIMATED, armsInterventionsModule interventions name: Implementation of cow's milk in decreasingly heated forms, interventions name: Implementation of hen's egg in decreasingly heated forms, outcomesModule primaryOutcomes measure: Maintained remission of EoE, secondaryOutcomes measure: Maintained remission only in step 1 of the diet, secondaryOutcomes measure: Association of remission with circulating IgG4 levels, secondaryOutcomes measure: Association of remission with IgG4 levels on biopsy, secondaryOutcomes measure: In vitro B cell test to mimic B cell activation after stimulation, secondaryOutcomes measure: Correlation between QoL and remission, secondaryOutcomes measure: Associated atopy, secondaryOutcomes measure: Associated food allergies, eligibilityModule sex: ALL, minimumAge: 12 Months, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: UZ Leuven Gasthuisberg, status: RECRUITING, city: Leuven, state: Vlaams-Brabant, zip: 3000, country: Belgium, contacts name: Dominique Bullens, Prof. Dr., role: CONTACT, phone: 0032 16 34 38 01, email: dominique.bullens@kuleuven.be, contacts name: Marleen Jannis, role: CONTACT, phone: 0032 16 34 38 01, email: marleen.jannis@uzleuven.be, geoPoint lat: 50.87959, lon: 4.70093, documentSection largeDocumentModule largeDocs typeAbbrev: Prot, hasProtocol: True, hasSap: False, hasIcf: False, label: Study Protocol, date: 2023-07-05, uploadDate: 2023-10-25T10:35, filename: Prot_000.pdf, size: 696874, hasResults: False
protocolSection identificationModule nctId: NCT06381206, orgStudyIdInfo id: No 475, briefTitle: Silodosin in Management of Lower Ureteral Stones, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-10-20, primaryCompletionDateStruct date: 2023-10-20, completionDateStruct date: 2023-10-25, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Syrian Private University, class: OTHER, descriptionModule briefSummary: This research aims to study the effectiveness of silodosin in the management of lower ureter stones larger than 6 mm in diameter in terms of affected ureter (right or left), the size of the stone, the degree of hydronephrosis, the rate of stone expulsion(day), whether the stone was completely expelled or not, and the side effects of silodosin., conditionsModule conditions: Stone, Kidney, designModule studyType: INTERVENTIONAL, phases: PHASE1, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ACTUAL, armsInterventionsModule interventions name: Silodosin, outcomesModule primaryOutcomes measure: Stone expulsion (yes), primaryOutcomes measure: Stone expulsion (no), eligibilityModule sex: ALL, minimumAge: 20 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Damascus university, city: Damascus, zip: 1, country: Syrian Arab Republic, geoPoint lat: 33.5102, lon: 36.29128, hasResults: False
protocolSection identificationModule nctId: NCT06381193, orgStudyIdInfo id: ESTR-01-2022, briefTitle: Study for the Management of Chronic and Functional Constipation Through the Intake of Probiotics and Prebiotics, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-03-03, primaryCompletionDateStruct date: 2023-07-10, completionDateStruct date: 2023-07-10, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Centros de Investigación de Nutrición y Salud, class: OTHER, collaborators name: Nutribiotica, descriptionModule briefSummary: The goal of this clinical trial is to learn if supplementation with prebiotics and/or probiotics can lead to an improvement in symptoms of patients with functional constipation. The main objectives are:* To evaluate the effect of the dietary supplements on the bowel frequency movements in patients with chronic functional constipation, after 8 weeks.* To evaluate the stool consistency after 8 weeks (Bristol scale).* To evaluate the quality of life scale score for patients with Constipation (CVE20 and GSRS scales), after 8 weeks.Participants are randomized into the following groups:* Group A: 20 assigned to probiotic + placebo* Group B: 20 assigned to prebiotic + placebo* Group C: 20 assigned to probiotic + prebiotic* Group D: 20 assigned to the placebo + placeboParticipants took 4 units of product per day (2 of each assigned product) for 2 months., conditionsModule conditions: Functional Constipation, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 80, type: ACTUAL, armsInterventionsModule interventions name: Probiotic, interventions name: Prebiotic, interventions name: Probiotic + Prebiotic, interventions name: Placebo, outcomesModule primaryOutcomes measure: 1. To evaluate the effect of the dietary supplements on the bowel frequency movements in patients with chronic functional constipation., secondaryOutcomes measure: To evaluate the stool consistency (Bristol scale)., secondaryOutcomes measure: To evaluate the quality of life scale score for patients with constipation (Quality of life questionnaire for patients with constipation, CVE-20), secondaryOutcomes measure: To evaluate the quality of life scale score for patients with constipation (Gastrointestinal Symptom Assessment Scale, GSRS scale)., eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Centros de Investigación en Nutrición y Salud SL. (Clínica CINUSA), city: Madrid, zip: 28036, country: Spain, geoPoint lat: 40.4165, lon: -3.70256, hasResults: False
protocolSection identificationModule nctId: NCT06381167, orgStudyIdInfo id: Endoscopic decompression, briefTitle: Endoscopic Decompression Versus Microscopic Decompression in Lumbar Canal Stenosis, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2027-05, completionDateStruct date: 2027-10, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: To compare between the clinical and surgical efficacies of bi-portal endoscopic and microscopic decompressive laminectomy in patients with degenerative lumbar spinal stenosis., conditionsModule conditions: Lumbar Spinal Stenosis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: SEQUENTIAL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 52, type: ESTIMATED, armsInterventionsModule interventions name: Endoscopic Decompressive Laminectomy, outcomesModule primaryOutcomes measure: Oswestry Disability Index ODI scores for low back pain and neuropathic pain, secondaryOutcomes measure: visual analog scale (VAS) score for low back and lower extremity radiating pain, secondaryOutcomes measure: European Quality of Life-5 Dimensions (EQ-5D) score, secondaryOutcomes measure: painDETECT score, eligibilityModule sex: ALL, minimumAge: 40 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06381141, orgStudyIdInfo id: CLN-619-002, briefTitle: A Study of CLN-619 (Anti-MICA/MICB Antibody) in Patients With Relapsed and Refractory Multiple Myeloma, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09, primaryCompletionDateStruct date: 2026-09, completionDateStruct date: 2027-03, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Cullinan Therapeutics Inc., class: INDUSTRY, descriptionModule briefSummary: A Phase 1b, Multicenter, Open-Label, Study to Investigate the Safety and Efficacy of CLN-619 (anti-MICA/MICB Antibody) in Patients with Relapsed and Refractory Multiple Myeloma, conditionsModule conditions: Multiple Myeloma, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: SEQUENTIAL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: CLN-619, outcomesModule primaryOutcomes measure: Proportion of participants reporting Adverse Events (AEs) and Serious Adverse Events (SAEs), primaryOutcomes measure: Changes in Eastern Cooperative Oncology Group (ECOG) performance, primaryOutcomes measure: Incidence of Dose-Limiting toxicity (DLTs), primaryOutcomes measure: Best Overall Response (BOR) per patient, primaryOutcomes measure: Overall Response Rate (ORR), primaryOutcomes measure: Duration of Response (DoR), primaryOutcomes measure: Clinical Benefit Rate (CBR), primaryOutcomes measure: Progression Free Survival (PFS), primaryOutcomes measure: Overall Survival (OS), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06381128, orgStudyIdInfo id: CAA by CT in children with CHD, briefTitle: Coronary Arteries Anomalies by CT in Children With CHD, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2025-01-01, primaryCompletionDateStruct date: 2026-01-01, completionDateStruct date: 2029-12-31, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: Delineate coronary artery anatomy and detection of coronary anomalies in children with complex cardiac anomalies by cardiac CT-angiography before total surgical correction., conditionsModule conditions: Cardiac Congenital Defects, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Cardiac CT, outcomesModule primaryOutcomes measure: Detection of coronary arteries anomalies by computed tomography angiography in children with congenital heart disease, eligibilityModule sex: ALL, minimumAge: 1 Day, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06381115, orgStudyIdInfo id: 23-006685, briefTitle: App-Based Optimization of Long-Term CPAP Adherence and Quality of Life, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2024-11, completionDateStruct date: 2024-11, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Mayo Clinic, class: OTHER, collaborators name: Arizona State University (ASU), descriptionModule briefSummary: The purpose of this study is to optimize the time of CPAP usage to at least 6 hours a night for 6 nights per week for people who have OSA with the help of a smartphone application called SmartWell24. This application aims to target CPAP adherence., conditionsModule conditions: Obstructive Sleep Apnea, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: SleepWell24 Application, outcomesModule primaryOutcomes measure: CPAP Adoption, primaryOutcomes measure: Change in Quality of Life, secondaryOutcomes measure: Change in sleep time, secondaryOutcomes measure: Change in physical activity, secondaryOutcomes measure: Change in sedentary time, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Mayo Clinic in Arizona, city: Scottsdale, state: Arizona, zip: 85259, country: United States, geoPoint lat: 33.50921, lon: -111.89903, locations facility: Mayo Clinic in Rochester, city: Rochester, state: Minnesota, zip: 55905, country: United States, geoPoint lat: 44.02163, lon: -92.4699, hasResults: False
protocolSection identificationModule nctId: NCT06381102, orgStudyIdInfo id: 20240134, briefTitle: Transcutaneous Vagus Nerve Stimulation (taVNS) Dosage Study 1, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-13, primaryCompletionDateStruct date: 2024-10-01, completionDateStruct date: 2024-10-01, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: University of Miami, class: OTHER, descriptionModule briefSummary: The purpose of this research study is to investigate the effects of different forms of a gentle form of electrical stimulation applied to the ear, known as transcutaneous auricular vagus nerve stimulation (taVNS). The research team is interested in how the different forms affect comfort and tolerability, as well as how well it works., conditionsModule conditions: Healthy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: OTHER, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: transcutaneous auricular vagus nerve stimulation 30/30, interventions name: transcutaneous auricular vagus nerve stimulation 10/10, outcomesModule primaryOutcomes measure: Tolerability measured by tolerability questionnaire, primaryOutcomes measure: Tolerability measured by self-report, secondaryOutcomes measure: Change in heart rate variability (HRV), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Miami, status: RECRUITING, city: Miami, state: Florida, zip: 33136, country: United States, contacts name: Gabriel Gonzalez, DPT, role: CONTACT, phone: 305-243-8117, email: gxg651@miami.edu, contacts name: Marlon Wong, PT, PhD, role: PRINCIPAL_INVESTIGATOR, contacts name: Gabriel Gonzalez, DPT, role: SUB_INVESTIGATOR, contacts name: Jessica Bolanos, DPT, role: SUB_INVESTIGATOR, geoPoint lat: 25.77427, lon: -80.19366, hasResults: False