hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06326632, orgStudyIdInfo id: RHPT/0022/023, briefTitle: Comparative Effectiveness Study of Constant-Load Versus Graded Aerobic Exercise in Obese Children With Bronchial Asthma, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-10-30, primaryCompletionDateStruct date: 2023-12-07, completionDateStruct date: 2023-12-07, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: This study aimed to compare the effect of constant-load aerobic exercise (CL-AE) and graded aerobic exercise (G-AE) on cardiopulmonary fitness, and functional capacity in a cohort of obese children with bronchial asthma (BA).A total of 78 children with BA were randomly assigned to the CL-AE group (n = 26, who underwent moderate-intensity aerobic training with the training load maintained at the same level throughout the entire program, besides the respiratory re-training program), the G-AE group (n = 26, received an intensity- and duration-graded aerobic training in addition to the respiratory re-training program), or the control group (n = 29, who only engaged in a respiratory re-training program). Interventions were administered three times/week for 12 successive weeks.The cardiopulmonary fitness and functional capacity were evaluated in the three groups before and after the completion of the assigned interventions., conditionsModule conditions: Bronchial Asthma, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: A prospective, three-arm, randomized controlled trial, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: A single-blind protocol was adopted. The researcher who collected the data was blind to the allocation of treatment, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 78, type: ACTUAL, armsInterventionsModule interventions name: Constant-load Aerobic Exercise, interventions name: Graded Aerobic exercise, interventions name: Respiratory Re-training, outcomesModule primaryOutcomes measure: Peak oxygen uptake, secondaryOutcomes measure: Six-minute walk test, secondaryOutcomes measure: Dyspnea, secondaryOutcomes measure: Fatigue, eligibilityModule sex: ALL, minimumAge: 8 Years, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Ragab K. Elnaggar, city: Al Kharj, state: Riyadh, country: Saudi Arabia, geoPoint lat: 24.15541, lon: 47.33457, hasResults: False
protocolSection identificationModule nctId: NCT06326619, orgStudyIdInfo id: SurvSysT, briefTitle: Survival Benefit of Primary Tumour Resection Compared to Systemic Therapy Alone in Stage IV Colorectal Cancer Patients, acronym: SurvSysT, statusModule overallStatus: COMPLETED, startDateStruct date: 2012-01-01, primaryCompletionDateStruct date: 2020-12-31, completionDateStruct date: 2020-12-31, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Medizinische Hochschule Brandenburg Theodor Fontane, class: OTHER, collaborators name: Clinical-Epidemiological Cancer Registry Brandenburg-Berlin, descriptionModule briefSummary: About 20-25 percent of all colorectal cancer patients are diagnosed with International Union Against Cancer (UICC) stage IV disease. The benefit of primary tumor resection in the palliative context is therefore of high concern. However, empirical evidence from randomized and observational studies is inconsistent.The objective of the present study is to compare the survival of palliative stage IV colorectal cancer patients selected for primary tumor resection and systemic treatment (PTR+SYST) to patients with systemic treatment only (SYST)., conditionsModule conditions: Colorectal Cancer, conditions: Neoadjuvant Systemic Therapy, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: RETROSPECTIVE, enrollmentInfo count: 480, type: ACTUAL, armsInterventionsModule interventions name: Primary tumor resection, interventions name: Systemic Therapy, outcomesModule primaryOutcomes measure: Survival, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06326593, orgStudyIdInfo id: P.T.REC/012/005049, briefTitle: Wii Aerobic Training in Inhalation-injury Children Post-thermal Burn, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-22, primaryCompletionDateStruct date: 2024-05-25, completionDateStruct date: 2024-06-01, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: MTI University, class: OTHER, descriptionModule briefSummary: Inhalation injury is a composite of multiple insults including: supra glottic thermal injury, subglottic airway and alveolar poisoning, and systemic poisoning from absorbed small molecule toxins. These contaminant insults independently affect each of the pulmonary functions as well as having a direct effect on systemic physiology. Further, anatomic characteristics can predispose patients to inhalation injury. For example, an infant will develop airway obstructions much faster than an adult due to reduced airway diameter. Understanding the contributions of each of these pathologies to the patient's disease is critical to managing inhalation injury.Wii fit aerobic training gives similar results with traditional rehabilitation practices, it causes less energy costs. This suggests that it can be a suitable rehabilitation tool for adult and elderly people with low energy levels. A review showed that video games are safe and feasible in the children with lung complications. Children' balance, aerobic and cognitive functions, quality of life improved and depressive mood decreased. WII aerobic games also make children to communicate better with other family members., conditionsModule conditions: Inhalation Injury, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Wii aerobic training, interventions name: conservative chest care, outcomesModule primaryOutcomes measure: Forced vital capacity (FVC), primaryOutcomes measure: forced expiratory volume in 1 second (FEV1), primaryOutcomes measure: peak expiratory flow (PEF), secondaryOutcomes measure: Upper and lower chest expansion (2nd intercostal space, xiphoid)]), secondaryOutcomes measure: Functional capacity 6-Minute Walk Test (6-MWT), secondaryOutcomes measure: Timed Up and Go test (TUG), eligibilityModule sex: ALL, minimumAge: 12 Years, maximumAge: 17 Years, stdAges: CHILD, contactsLocationsModule locations facility: Heba Elfeky, status: RECRUITING, city: Cairo, zip: 6347113, country: Egypt, contacts name: ahmed m el fahl, phd, role: CONTACT, phone: 00201097782441, email: nn_ee_mm_oo@yahoo.com, geoPoint lat: 30.06263, lon: 31.24967, locations facility: Ahmed Mohamed Ahmed Abdelhady, status: RECRUITING, city: Cairo, country: Egypt, contacts name: Ahmed El Fahl, ph.d, role: CONTACT, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06326580, orgStudyIdInfo id: MS.22.09.2144, briefTitle: Clinical Prediction Model of Obstructive Sleep Apnea at Mansoura University Hospitals, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-10-20, primaryCompletionDateStruct date: 2023-10-20, completionDateStruct date: 2024-02-20, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Mansoura University, class: OTHER, descriptionModule briefSummary: Obstructive sleep apnea syndrome (OSAS)is a sleep breathing disorder manifested by complete apnea or partial hypopnea obstruction of the upper airway, which often remains undiagnosed and untreated (Kuczynski, W., 2019). These episodes, which should be more than 5 per hour and last at least 10 s, can lead to a sleep fragmentation and hypoxia (Huon, L.-K.A., 2017). OSAS predominantly affects 26% of individuals between 30 and 70 years in the U.S (apnea hypopnea index ≥5 events per hour) (Schwartz, M., 2018).Obstructive sleep apnea it is increasingly recognized as an independent risk factor for cardiac, neurologic, and perioperative morbidities. Yet this disorder remains undiagnosed in a substantial portion of our population. It is imperative for all physicians to remain vigilant in identifying patients with signs and symptoms consistent with OSA (Park, J. G., 2011).The test of hypothesis is to design a clinical prediction model of obstructive sleep apnea from collected data of the patients having symptoms of obstructive sleep apnea and the results of their sleep study, conditionsModule conditions: Osa Syndrome, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: OTHER, enrollmentInfo count: 1129, type: ACTUAL, outcomesModule primaryOutcomes measure: The recorded data of all patients which include all their symptoms and comorbidities as well as their use of any regular medications will be collected., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Mansoura University, city: Mansoura, state: Dakhlia, zip: 050, country: Egypt, geoPoint lat: 31.03637, lon: 31.38069, hasResults: False
protocolSection identificationModule nctId: NCT06326567, orgStudyIdInfo id: 84032, briefTitle: Comprehensive Connected Cancer Care (C4): Intervention Evaluation, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-01, primaryCompletionDateStruct date: 2025-06, completionDateStruct date: 2025-06, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Timothy Mullett, class: OTHER, collaborators name: Merck Sharp & Dohme LLC, descriptionModule briefSummary: The C4 program aims to provide a multi-level intervention program (Patient Level, Healthcare Team and Healthcare System Level) that improves the coordination of care with supportive/ancillary care providers and community services through the use of patient navigation and a digital needs assessment and a closed-loop referral system and improves patient-centered communication and engagement in care through skills training for the healthcare team and provision of culturally appropriate patient educational tools and resources. The program components incorporate three areas that are critical to improving patient-centered care: coordination of care, patient-centered communication and engagement, and psychosocial care and other supportive services., conditionsModule conditions: Cancer, conditions: Health Care Utilization, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: NONE, enrollmentInfo count: 300, type: ESTIMATED, armsInterventionsModule interventions name: C4 Program, outcomesModule primaryOutcomes measure: Change in Health Related Quality of Life (FACT-G7), secondaryOutcomes measure: Overall Survival, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Kentucky, status: RECRUITING, city: Lexington, state: Kentucky, zip: 40506, country: United States, contacts name: Yvonne Taul, RN, role: CONTACT, phone: 859-323-2354, email: Yvonne.Taul@uky.edu, geoPoint lat: 37.98869, lon: -84.47772, hasResults: False
protocolSection identificationModule nctId: NCT06326554, orgStudyIdInfo id: 22-5933, briefTitle: Single Arm Pilot Trial of Virtual and In-person STEP2, acronym: STEP2, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-01-01, completionDateStruct date: 2025-01-01, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: University Health Network, Toronto, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to assess the feasibility of offering oncology patients a referral to the outpatient palliative care clinic based on virtual symptom screening before oncology clinic appointments, and to qualitatively explore factors patients consider when deciding to accept or defer a visit to this clinic.Participants will be asked to complete questionnaires assessing quality of life, symptom burden, depression, anxiety, and satisfaction with care at baseline, 2, 4, and 6 months., conditionsModule conditions: Oncology, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: Single arm intervention, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: Virtual and in-person Symptom screening with Targeted Early Palliative care (STEP2), outcomesModule primaryOutcomes measure: FACIT-PAL 14, secondaryOutcomes measure: FACIT-PAL 14, secondaryOutcomes measure: ESAS-r-CS, secondaryOutcomes measure: PHQ-9, secondaryOutcomes measure: FAMCARE-P16, secondaryOutcomes measure: Generalized Anxiety Disorder-7, secondaryOutcomes measure: Patient Global Impression of Change, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06326541, orgStudyIdInfo id: okutan, briefTitle: The Effect of Listening to the Holy Quran on Vital Signs in Coma Patients, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-01-05, primaryCompletionDateStruct date: 2023-12-10, completionDateStruct date: 2023-12-30, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Bitlis Eren University, class: OTHER, descriptionModule briefSummary: The aim of this study is to examine the effect of the Holy Quran listened to to coma patients on their vital signs.Does listening to the Holy Quran have a positive effect on the life values of coma patients?, conditionsModule conditions: Sequelae of; Complications Surgical and Medical Care, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: single group pretest-posttest, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 72, type: ACTUAL, armsInterventionsModule interventions name: music therapy, outcomesModule primaryOutcomes measure: systolic blood pressure- (mmHg), primaryOutcomes measure: diastolic blood pressure- (mmHg), primaryOutcomes measure: pulse (number of beats/min), primaryOutcomes measure: body temperature (degrees Celsius), primaryOutcomes measure: saturation (%-oxygen saturation), eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Bitlis Eren University, city: Bitlis, zip: 13100, country: Turkey, geoPoint lat: 38.40115, lon: 42.10784, hasResults: False
protocolSection identificationModule nctId: NCT06326528, orgStudyIdInfo id: SGLT2 inhibitors, briefTitle: SGLT2 Inhibitors and Perioperative Period, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2025-04-01, completionDateStruct date: 2025-10-01, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: The expanded use of SGLT2 inhibitors motivates us to assess the role of SGLT2 inhibitors in perioperative period on patients who will undergo cardiac surgery in Assiut University., conditionsModule conditions: Perioperative Complication, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: SGLT2 inhibitor, outcomesModule primaryOutcomes measure: Difference of cardiac function by speckle tracing between patients who will receive SGLT2 and patients who not., eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06326515, orgStudyIdInfo id: Government College University, briefTitle: Cognitive Behavior Therapy for Depression, Stigmatization, Criminogenic Cognition, and Quality of Life Among Patients With Opioid Use Disorder (OUD): A Randomized Control Trial., acronym: CBT with OUD, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2024-07-20, completionDateStruct date: 2024-09-10, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Government College University Faisalabad, class: OTHER, descriptionModule briefSummary: to investigate the impact of cognitive behavior therapy for psychiatric problems among patients with opioid use disorder with relapse condition.In this randomize control trail (RCT), N=120 patients with relapse condition would be taken. After enrolment patients' eligibility assessment would be completed and then n=60 patients would be allocated to experimental (n=30) and waitlist control (n=30) through random assignment. Patient's age range would be between 20 to 30 years., conditionsModule conditions: Psychoeducation, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized control trial design would be used in this study. It would be two arm study and there would be two groups an experimental and wait-list control group. Experimental group will receive intervention and another group would be placed in waitlist. In this research, parallel group design would be used. We will give treatment to all participants in a parallel way. Allocation ratio and framework would be equivalence i.e., treatment group and control group would be equal number of participants, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: psychoeducation, interventions name: Stigma Reduction and Relapse Management, outcomesModule primaryOutcomes measure: The Alcohol, Smoking and Substance Involvement Screening Test (ASSIST; Henry-Edwards et al., 2003; Hussain et al., 2022)., primaryOutcomes measure: Criminogenic Cognition Scale (CCS;Tangney, at el, 2012; Jamil & Fatima, 2018):, primaryOutcomes measure: Patient Health Questionnaire (PHQ-9; Robert et al. 1999; Ahmad et al, 2018)., primaryOutcomes measure: Relapse Risk Scale (RRS; Marlatt & Gordon, 1985; Hussain et al., 2016):, primaryOutcomes measure: Perceived Stigma of Addiction Scale, primaryOutcomes measure: Brief Cope Inventory (BCI), secondaryOutcomes measure: World Health Organization Quality-of-Life Scale, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 30 Years, stdAges: ADULT, contactsLocationsModule locations facility: Dr Khalid Mahmood, city: Faisalābad, state: Punjab, country: Pakistan, geoPoint lat: 31.41554, lon: 73.08969, hasResults: False
protocolSection identificationModule nctId: NCT06326502, orgStudyIdInfo id: 22ETN101-2IND001, briefTitle: A Safety and Efficacy Study of Multiple Tyrosine Kinase Inhibitor Drug (ETN101) in Advanced Hepatocellular Carcinoma, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-07, primaryCompletionDateStruct date: 2027-03-07, completionDateStruct date: 2027-06-07, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Etnova Therapeutics Corp., class: INDUSTRY, descriptionModule briefSummary: ETN101 is a multiple tyrosine kinase inhibitor (mTKI) targeting fms-like tyrosine kinase 3 (FLT3), receptor tyrosine kinase (KIT), vascular endothelial growth factor receptor 2 (VEGFR2), and platelet-derived growth factor receptor beta. Both in vitro and in vivo studies showed that ETN101 treatment/administration inhibited cancer cell survival and proliferation. In animal models, ETN101 had antitumor activity when administered to animals that did not respond to conventional targeted anticancer agents., conditionsModule conditions: Hepatocellular Carcinoma, conditions: Advanced Hepatocellular Carcinoma, conditions: Liver Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: ETN101, outcomesModule primaryOutcomes measure: Dose-limiting Toxicity (DLT), eligibilityModule sex: ALL, minimumAge: 19 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Seoul National University Hospital, status: RECRUITING, city: Seoul, zip: 03080, country: Korea, Republic of, geoPoint lat: 37.566, lon: 126.9784, locations facility: Severance Hospital, status: RECRUITING, city: Seoul, zip: 03722, country: Korea, Republic of, geoPoint lat: 37.566, lon: 126.9784, hasResults: False