hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06370364, orgStudyIdInfo id: 25, briefTitle: Nurses' Practice of Safe Blood Transfusion in Surgical and Critical Care Units, statusModule overallStatus: COMPLETED, startDateStruct date: 2020-12-01, primaryCompletionDateStruct date: 2021-04-30, completionDateStruct date: 2021-04-30, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Matrouh University, class: OTHER, descriptionModule briefSummary: Blood transfusions are an important part of nursing procedure. Nurses play a key role in safely administering blood products to patients in surgical and critical care unit, conditionsModule conditions: Practice Nurse's Scope, conditions: Blood Transfusion, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 350, type: ACTUAL, armsInterventionsModule interventions name: Nurses' Practice of Safe Blood Transfusion, outcomesModule primaryOutcomes measure: Questionnaire to measure factors affecting safe blood transfusion, primaryOutcomes measure: observational checklist to measure nurses' practice of safe blood transfusion, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Faculty of Nursing, Matrouh University, city: Mersa Matruh, zip: 002, country: Egypt, geoPoint lat: 31.3529, lon: 27.23725, hasResults: False
protocolSection identificationModule nctId: NCT06370351, orgStudyIdInfo id: SENS-501-101, secondaryIdInfos id: 2023-504466-28-00, type: CTIS, briefTitle: A Phase I/II Clinical Trial With SENS-501 in Children Suffering From Severe to Profound Hearing Loss Due to Otoferlin (OTOF) Mutations, acronym: AUDIOGENE, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-30, primaryCompletionDateStruct date: 2027-04, completionDateStruct date: 2031-04, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Sensorion, class: INDUSTRY, descriptionModule briefSummary: This study intends to assess safety, tolerability, and efficacy of SENS-501 in children between the ages of 6-31 months with pre-lingual hearing loss due to a mutation in the Otoferlin gene., conditionsModule conditions: OTOF Gene Mutation, conditions: DFNB9, conditions: Congenital Deafness, conditions: Hearing Disorders, conditions: Ear Diseases, conditions: Otorhinolaryngologic Diseases, conditions: Deafness, conditions: Hearing Loss, Sensorineural, designModule studyType: INTERVENTIONAL, phases: PHASE1, phases: PHASE2, designInfo allocation: NON_RANDOMIZED, interventionModel: SEQUENTIAL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 12, type: ESTIMATED, armsInterventionsModule interventions name: SENS-501 administration, outcomesModule primaryOutcomes measure: Safety and tolerability of SENS-501, primaryOutcomes measure: Efficacy of SENS-501 assessed by ABR, secondaryOutcomes measure: Safety and tolerability of SENS-501, secondaryOutcomes measure: Efficacy of SENS-501 assessed by ABR, secondaryOutcomes measure: Efficacy of SENS-501 assessed by PTA, secondaryOutcomes measure: Clinical performance of the administration system, secondaryOutcomes measure: Safety of the administration system, secondaryOutcomes measure: Usability of the administration system, eligibilityModule sex: ALL, minimumAge: 6 Months, maximumAge: 31 Months, stdAges: CHILD, contactsLocationsModule locations facility: Hopital Necker Enfants Malades, city: Paris, zip: 75015, country: France, contacts name: Natalie LOUNDON, Pr, role: CONTACT, phone: +33(0)171396782, email: natalie.loundon@aphp.fr, contacts name: Natalie LOUNDON, Pr, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 48.85341, lon: 2.3488, hasResults: False
protocolSection identificationModule nctId: NCT06370338, orgStudyIdInfo id: 2024B0101, briefTitle: Cardiothoracic Critical Care as Subspecialty and Its Core Competencies, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-11, primaryCompletionDateStruct date: 2025-04-30, completionDateStruct date: 2025-04-30, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: Ohio State University, class: OTHER, descriptionModule briefSummary: The aim of this study is to develop a consensus on the curriculum for training cardiothoracic critical care by first evaluating the need for the field, based on a Delphi consensus among a panel of experts in this field., conditionsModule conditions: Consensus Development, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 68, type: ESTIMATED, armsInterventionsModule interventions name: Delphi Questionnaire, outcomesModule primaryOutcomes measure: Degree of consensus on the curriculum for training cardiothoracic critical care by first evaluating the need for the field, secondaryOutcomes measure: Degree of consensus on defining training core competencies, goals, and milestones., secondaryOutcomes measure: Degree of consensus on the definitions of "Scholarship", "Patient", "Safety", "Quality", eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The Ohio State University Wexner Medical Center, status: RECRUITING, city: Columbus, state: Ohio, zip: 43210, country: United States, contacts name: Alberto Uribe, MD, role: CONTACT, phone: 614-293-3559, email: alberto.uribe@osumc.edu, contacts name: Jeremy Reeves, BA, role: CONTACT, phone: 6148067569, email: jeremy.reeves@osumc.edu, geoPoint lat: 39.96118, lon: -82.99879, hasResults: False
protocolSection identificationModule nctId: NCT06370325, orgStudyIdInfo id: 23-00987, briefTitle: Neuromuscular Electrical Stimulation in Foot and Ankle Surgery, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2024-08, completionDateStruct date: 2024-08, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: NYU Langone Health, class: OTHER, descriptionModule briefSummary: This is a pilot randomized controlled trial, wherein the intervention group will undergo NMES five days a week beginning three weeks postoperative and lasting for ten weeks. Both the control and intervention groups will start standard physical therapy six weeks postoperative. Primary outcome measure will be the isometric strength of the gastrocnemius muscle. The secondary outcomes will comprise subjective clinical evaluations (using the Lower Extremity Functional Scale \[LEFS\]), functional assessments such as the sit-to-stand test, 2-minute walk test, stair climb test and objective clinical evaluation using contralateral comparison of calf circumference., conditionsModule conditions: Ankle Fractures, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: VPOD Wireless Tens Unit, interventions name: Physical Therapy, interventions name: Biodex, outcomesModule primaryOutcomes measure: Isometric Strength of Gastrocnemius Muscle, primaryOutcomes measure: Isometric Strength of Gastrocnemius Muscle, primaryOutcomes measure: Isometric Strength of Gastrocnemius Muscle, primaryOutcomes measure: Bilateral Calf Circumference, primaryOutcomes measure: Bilateral Calf Circumference, primaryOutcomes measure: Bilateral Calf Circumference, secondaryOutcomes measure: Lower Extremity Functional Scale (LEFS) Questionnaire Score, secondaryOutcomes measure: Lower Extremity Functional Scale (LEFS) Questionnaire Score, secondaryOutcomes measure: Lower Extremity Functional Scale (LEFS) Questionnaire Score, secondaryOutcomes measure: Sit-to-Stand Test, secondaryOutcomes measure: Sit-to-Stand Test, secondaryOutcomes measure: Sit-to-Stand Test, secondaryOutcomes measure: 2 Minute Walk Test, secondaryOutcomes measure: 2 Minute Walk Test, secondaryOutcomes measure: 2 Minute Walk Test, secondaryOutcomes measure: Stair Climb Test, secondaryOutcomes measure: Stair Climb Test, secondaryOutcomes measure: Stair Climb Test, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: NYU Langone Health, city: New York, state: New York, zip: 10016, country: United States, geoPoint lat: 40.71427, lon: -74.00597, hasResults: False
protocolSection identificationModule nctId: NCT06370312, orgStudyIdInfo id: 2023-07921-01, briefTitle: Analysis of Articular Biomarkers From Osteoarthritic Thumb Basal Joints, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2026-04-30, completionDateStruct date: 2027-04-30, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Region Skane, class: OTHER, descriptionModule briefSummary: The study project aims at examining molecular markers in synovial fluid, bone and articular cartilage from osteoarthritic thumb basal joints. The degradation of extracellular matrix (ECM) proteins in thumb basal joints will be evaluated in association to the metabolic profile of the patient, but we also aim to compare the ECM degradation and inflammatory profiles with articular cartilage degradation ECM profile from knee joints with osteoarthritis. A third aim is to evaluate associations between patient-reported hand function, pain, strength and range of thumb motion to analyses of synovial fluid., conditionsModule conditions: Osteoarthritis Thumb, conditions: Osteoarthritis, Knee, conditions: Metabolic Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: Trapeziectomy, outcomesModule primaryOutcomes measure: Serum cholesterol levels, eligibilityModule sex: ALL, minimumAge: 25 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06370299, orgStudyIdInfo id: 2023-06402-01, briefTitle: Screening of Multidrug Resistant Bacteria, and the Clinical Implication for the Patient, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2025-06, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Region Skane, class: OTHER, collaborators name: Lund University, descriptionModule briefSummary: The goal of this observational study is to evaluate the screening for multidrug resistant bacteria in patients admitted to hospitals in Scania. The main questions it aims to answer are:* admission rates after screening* 30-day and one-year mortality after screening Participants will be evaluated for positive screening results with following multidrug resistant gram negative bacilli: ESBL producing Enterobacterales, Carbapenemase producing Enterobacterales, Carbapenem resistant P.aeruginosa and carbapenem resistant Acinetobacter baumannii. Researchers will compare patients with positive and negative screening results to see, if the relative risks in the two groups differ in admission rates and mortality., conditionsModule conditions: Multi-antibiotic Resistance, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 10000, type: ESTIMATED, armsInterventionsModule interventions name: (exposure of) MDR carriage, outcomesModule primaryOutcomes measure: The ratio of the probability of all-cause admission in patients who are screening positive to the probability of all-cause admission in patients who are screening negative., primaryOutcomes measure: The ratio of the probability of death in patients who are screening positive to the probability of death in patients who are screening negative., primaryOutcomes measure: The ratio of the probability of antibiotic use in patients who are screening positive to the probability of antibiotic use in patients who are screening negative., secondaryOutcomes measure: prevalence of positive screening results, secondaryOutcomes measure: prevalence of MDR in clinical samples, secondaryOutcomes measure: time to first occurrence of phenotypically same MDR as in screening, secondaryOutcomes measure: prevalence of MDR in clinical samples in patients with negative screening results, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06370286, orgStudyIdInfo id: PACNL_rueihongli_CE_IC, briefTitle: The Effect of Acute Concurrent Exercise on Inhibitory Control: An Event-related Potential Study, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-02-15, primaryCompletionDateStruct date: 2021-08-15, completionDateStruct date: 2022-02-15, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: National Taiwan Normal University, class: OTHER, descriptionModule briefSummary: The present study aimed to determine the effects of acute concurrent exercise on inhibitory control via behavioral and event-related potential approaches and to examine its potential mediational role on lactate among younger adults. The main questions it aims to answer are: (1) Does acute concurrent exercise improve inhibitory control via behavioral and event-related potential approaches? (2) Does lactate play a potential mediational role in the effect of acute concurrent exercise on inhibitory control?, conditionsModule conditions: Exercise, conditions: Cognition, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Participants were randomly assigned to either a concurrent exercise (CE), aerobic exercise (AE), or control (CON) group. Participants in the CE group engaged in 12-minutes of AE (40%-59% of heart rate reserve \[HRR\]) coupled with 13-minutes of resistance exercise (1 set, with 75% of 10-repetition maximum, and 12 repetitions of 8 movements). The AE group participated in 25 minutes of AE (40%-59% HRR). Prior to and following exercise onset, participants in both the CE and AE groups completed a 5-minute warm-up and cool-down. Participants in the CON group read books for 35 minutes. Lactate concentrations were measured at timepoint of 0-, 17-, and 30-minutes relative to the treatment onset. Response time (RT) and accuracy in the Stroop test, as well as P3 amplitudes, were assessed before and after the treatment., primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 78, type: ACTUAL, armsInterventionsModule interventions name: concurrent exercise (CE), interventions name: aerobic exercise (AE), outcomesModule primaryOutcomes measure: Inhibitory control, secondaryOutcomes measure: Blood lactate, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 30 Years, stdAges: ADULT, contactsLocationsModule locations facility: Department of Physical Education and Sport Sciences, National Taiwan Normal University, city: Taipei, zip: 106, country: Taiwan, geoPoint lat: 25.04776, lon: 121.53185, hasResults: False
protocolSection identificationModule nctId: NCT06370234, orgStudyIdInfo id: 201412166MINA, briefTitle: The Prediction Model of NAC Response for Breast Cancer Based on The Parametric Dynamics Features., statusModule overallStatus: COMPLETED, startDateStruct date: 2015-04-21, primaryCompletionDateStruct date: 2019-06-30, completionDateStruct date: 2020-03-03, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: National Taiwan University Hospital, class: OTHER, collaborators name: Ministry of Science and Technology, Taiwan, descriptionModule briefSummary: The main purpose of this study is to develop a computer-aided prediction model for NAC treatment response. Based on the heterogeneity of internal parametric tumor composition commonly observed, this study will utilize the histologic characteristics and treatment response to investigate the image features as input data for predicting treatment response using Deep Learning technology. Using this technique, preoperative treatment evaluation may be facilitated by tumor heterogeneity analysis from developed dynamic radiomics, and the possibility of personal medicine can be realized not far ahead. In the first two years of this study using images from DCE-MRI, PET/CT and QDS-IR, we plan to develop the image processing algorithms, including segmenting breast and tumor region, extracting image feature which reflects angiogenic properties and permeability of tumor, which are highly correlated with NAC treatment response. During the third year of the project, the morphology and texture features from first two years can be combined for PET/MRI and prediction model can be achieved in accordance with the features extracted from dynamic features extraction using longitudinal images of PET/MRI., conditionsModule conditions: Breast Cancer, conditions: Chemotherapy Effect, conditions: Diffusion Weighted MRI, conditions: PET Imaging, conditions: Multiparametric Magnetic Resonance Imaging, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 60, type: ACTUAL, armsInterventionsModule interventions name: Whole body 18F-FDG Positron Emission Tomography, outcomesModule primaryOutcomes measure: Model Prediction power of pathological complete response(pCR), primaryOutcomes measure: Comparison of models in prediction of pathological complete response(pCR), eligibilityModule sex: FEMALE, minimumAge: 20 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06370221, orgStudyIdInfo id: psoriatic Arthritis, briefTitle: The Effect of Psoriatic Arthritis on Female Sexual Dysfunction, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2024-12-20, completionDateStruct date: 2024-12-30, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Egymedicalpedia, class: INDUSTRY, descriptionModule briefSummary: Psoriasis is one of the most common immunemediated chronic inflammatory skin disorders., conditionsModule conditions: Psoriatic Arthritis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 180, type: ESTIMATED, armsInterventionsModule interventions name: The effect of psoriatic Arthritis, outcomesModule primaryOutcomes measure: Evaluation of female sexual function, eligibilityModule sex: FEMALE, minimumAge: 20 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Qena Hospital, city: Qinā, country: Egypt, contacts name: Eisa Hegazy, Assist.Prof, role: CONTACT, phone: 01094337795, email: eisa_mohamed4152@med.svu.edu.eg, geoPoint lat: 26.16418, lon: 32.72671, hasResults: False
protocolSection identificationModule nctId: NCT06370208, orgStudyIdInfo id: LUMHS/B12/Temp/13.04.2024, briefTitle: Prophylactic Effect of Probiotic Streptococcus Salivarius K12 Against Recurrent Streptococcus Pyogenes Pharyngotonsillitis Infection in Pediatrics, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2024-11-30, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Liaquat University of Medical & Health Sciences, class: OTHER, descriptionModule briefSummary: Recurrent Streptococcus pyogenes pharyngotonsillitis infection in children presents a significant health concern, characterized by frequent episodes of sore throat, fever, and swollen tonsils. These recurrent infections can lead to missed school days, discomfort, and potential complications if left untreated. Current treatment typically involves antibiotics to eradicate the bacterial infection. However, drawbacks exist with this approach, including the risk of antibiotic resistance, disruption of the gut microbiota, and potential adverse effects such as gastrointestinal upset or allergic reactions. Moreover, antibiotics do not prevent future episodes and may contribute to recurrent infections by disrupting the balance of the throat microbiome. Therefore, there is a growing interest in alternative approaches such as probiotics, which aim to support the body's natural defenses and restore microbial balance in the throat and oral cavity., conditionsModule conditions: Streptococcus Pyogenes Pharyngotonsillitis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Probiotic Bactoblis® (Streptococcus salivarius K12), outcomesModule primaryOutcomes measure: Recurrence of Streptococcus pyogenes pharyngotonsillitis infection, primaryOutcomes measure: Probiotic safety and tolerability, secondaryOutcomes measure: Protection against viral infection, secondaryOutcomes measure: Protection against Acute Otitis Media infection, secondaryOutcomes measure: Protection against respiratory infection, secondaryOutcomes measure: Protection against Rhinitis, secondaryOutcomes measure: Protection against flu, secondaryOutcomes measure: Protection against Enteritis, secondaryOutcomes measure: Protection against Stomatitis, eligibilityModule sex: ALL, minimumAge: 3 Years, maximumAge: 10 Years, stdAges: CHILD, contactsLocationsModule locations facility: Liaquat University of Medical and Health Sciences, city: Jamshoro, zip: 76090, country: Pakistan, contacts name: Dr. Ikram Ujjan, MBBS, PhD, role: CONTACT, phone: 03000506955, email: amjadkhan@lumhs.edu.pk, geoPoint lat: 25.43773, lon: 68.28522, hasResults: False