protocolSection identificationModule nctId: NCT06336070, orgStudyIdInfo id: 2024-FIS-3251696, secondaryIdInfos id: CIACIF/2022/368, type: OTHER_GRANT, domain: Regional Ministry of Education, Universities and Employment - Generalitat Valenciana, briefTitle: Metabolic Flexibility and Autonomic Control After Muscle Power vs Metabolic Power Training in Postmenopausal Oncological Women: the POWER Health Study, acronym: POWER Health, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2027-12-31, completionDateStruct date: 2028-12-31, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: University of Valencia, class: OTHER, collaborators name: Generalitat Valenciana, descriptionModule briefSummary: POWER Health is a randomized clinical trial with a two-arm parallel design whose objectives are 1) to study metabolic flexibility and autonomic function (both capacities that describe cardiovascular health) in a sample of postmenopausal oncological women vs postmenopausal untreated controls (CT); and 2) to analyze the impact of two different 8-week physical exercise supervised interventions: HIIT training vs strength training focused on muscle power, on both cardiovascular capacities in these populations., conditionsModule conditions: Breast Cancer Female, conditions: Cardiometabolic Syndrome, conditions: Metabolism Disorder, Lipid, conditions: Autonomic Dysfunction, conditions: Cardiovascular Diseases in Old Age, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 56, type: ESTIMATED, armsInterventionsModule interventions name: HIIT program (8 weeks), interventions name: MPI program (8 weeks), outcomesModule primaryOutcomes measure: Fat oxidation during incremental test, primaryOutcomes measure: Detrended Fluctuation Analysis, secondaryOutcomes measure: Weight, secondaryOutcomes measure: Height, secondaryOutcomes measure: Calf, waist and hip circumferences., secondaryOutcomes measure: Lean mass, secondaryOutcomes measure: Fat-free mass, secondaryOutcomes measure: Visceral adipose tissue, secondaryOutcomes measure: Bone Mass, secondaryOutcomes measure: Fat mass, secondaryOutcomes measure: Blood Pressure, secondaryOutcomes measure: Oxygen Saturation, secondaryOutcomes measure: Sarcopenia, secondaryOutcomes measure: Physical activity and sedentariness, secondaryOutcomes measure: Lactate, secondaryOutcomes measure: Rating Perceived Exertion, secondaryOutcomes measure: Visual Analogue Scale of Pain, secondaryOutcomes measure: Cadence, secondaryOutcomes measure: Mechanical Power, secondaryOutcomes measure: Muscle Power 5STS, secondaryOutcomes measure: Basal metabolic rate, secondaryOutcomes measure: Respiratory exheange ratio at rest, secondaryOutcomes measure: Fat oxidation at rest, secondaryOutcomes measure: Carbohydrate oxidation at rest, secondaryOutcomes measure: Carbohydrate oxidation during incremental test, secondaryOutcomes measure: Energy expenditure during incremental test, secondaryOutcomes measure: FATmax intensity, secondaryOutcomes measure: VO2peak, secondaryOutcomes measure: Sample Entropy, secondaryOutcomes measure: SD1/SD2 ratio, secondaryOutcomes measure: The root mean square of successive differences between normal heartbeats (RMSSD), eligibilityModule sex: FEMALE, minimumAge: 35 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Faculty of Physical Activity and Sport Sciences, status: RECRUITING, city: Valencia, state: Comunidad Valenciana, zip: 46010, country: Spain, contacts name: Cristina Blasco Lafarga, PhD, role: CONTACT, phone: 64372, phoneExt: 9638, email: m.cristina.blasco@uv.es, contacts name: Jordi Monferrer-Marín, Predoctoral student, role: SUB_INVESTIGATOR, contacts name: Ainoa Roldán, PhD, role: SUB_INVESTIGATOR, contacts name: Jørn Wulff Helge, PhD, role: SUB_INVESTIGATOR, geoPoint lat: 39.46975, lon: -0.37739, hasResults: False