hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06381089, orgStudyIdInfo id: VNS004, briefTitle: Effect Of Robotic Rehabilitation And Vagus Nerve Stimulation In Ischemia Stroke Patients, acronym: ERRVNS, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-10, primaryCompletionDateStruct date: 2024-07-10, completionDateStruct date: 2024-08-10, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: SEFA HAKTAN HATIK, class: OTHER, descriptionModule briefSummary: This study was conducted in patients with ischemic stroke; This study was conducted to examine the effect of robotic rehabilitation and transcutaneous auricular vagal nerve stimulation applied in addition to robotic rehabilitation on the patient's functional level and autonomic nervous system.40 people over the age of 18 participated in the study. They were randomly divided into two groups: robotic rehabilitation and transcutaneous auricular vagal nerve stimulation applied in addition to robotic rehabilitation. While the robotic rehabilitation group received Lokomat and neurological rehabilitation, the other group received stimulation with the Vagustim device, which is applied non-invasively through the ear, in addition to Lokomat and neurological rehabilitation. Spasticity, autonomic nervous system, walking speed, motor function, quality of life, muscle activity and pain were evaluated in both groups before starting treatment and six weeks after treatment. In the study, significance was evaluated at p\<0.05 level., conditionsModule conditions: Ischemic Stroke, conditions: Vagus Nerve Stimulation, conditions: Robotic Rehabilitation, conditions: Autonomic Nervous System, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Robotic Rehabilitation, interventions name: Transcutaneous Auricular Vagal Nerve Stimulation, outcomesModule primaryOutcomes measure: Numerical Pain Rating Scale, primaryOutcomes measure: Stroke Specific Quality of Life Scale, primaryOutcomes measure: 10 Meter Walk Test, primaryOutcomes measure: Fugl-Meyer Assessment Lower Extremity, primaryOutcomes measure: Modified Ashworth Scale, primaryOutcomes measure: Electromyography, primaryOutcomes measure: Autonomic Nervous System, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06381076, orgStudyIdInfo id: IRB202400087, briefTitle: Examining the Impact of High-protein Oral Supplement With Liposomal Curcumin on Inflammation Markers and Oxidative Stress in Adults Undergoing Hemodialysis., statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-08, primaryCompletionDateStruct date: 2025-12, completionDateStruct date: 2025-12, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-26, sponsorCollaboratorsModule leadSponsor name: University of Florida, class: OTHER, descriptionModule briefSummary: A 12-week double-blind randomized control trial will be conducted among adults on hemodialysis (n=15) to determine the impact of liposomal curcumin in a high-protein product on inflammation markers and oxidative stress. Participants will be randomized via a computer-generator into either the control or intervention group. Participants in each group will be given a total of 38 g of a high protein product with or without 7 mls of liposomal curcumin for a total of 8 weeks. At baseline, weeks 8 and 12, participants will have blood sampled and complete a 3-day 24-hour recalls (2 non-dialysis days and 1 dialysis day) and a quality of life survey., conditionsModule conditions: Chronic Kidney Disease 5D, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized comparator-controlled trial, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: Participants will receive a 3-digit coded product that either contains 7 mls of liposomal curcumin or food colorant., whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Liposomal curcumin, interventions name: Food colorant, outcomesModule primaryOutcomes measure: high-sensitivity C-reactive protein, secondaryOutcomes measure: Advanced glycation end products, secondaryOutcomes measure: fatty acid byproduct - 4-hydroxynon-enal, secondaryOutcomes measure: fatty acid byproduct - malondialdehyde, secondaryOutcomes measure: fatty acid byproduct - 8-F2 isoprostanes, secondaryOutcomes measure: Klotho, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06381063, orgStudyIdInfo id: PI2023_843_0152, briefTitle: Non-steroidal Anti-inflammatory in Cardiac Surgery, acronym: KETOPAIN, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-27, primaryCompletionDateStruct date: 2027-03, completionDateStruct date: 2027-07, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Centre Hospitalier Universitaire, Amiens, class: OTHER, collaborators name: University Hospital, Rouen, collaborators name: University Hospital, Lille, descriptionModule briefSummary: Non-steroidal anti-inflammatory drugs (NSAID) are part the multimodal strategy in pain management after surgery. However, major concerns are raised in cardiac surgery given the potential side effects of NSAID with more bleeding and acute kidney injury. The investigators hypothesized that NSAID are safe in the early postoperative course after cardiac surgery with respect to contraindication., conditionsModule conditions: Acute Postoperative Pain, conditions: Non-steroidal Anti-inflammatory Drugs, conditions: Cardiac Surgery, conditions: Pain Intensity, conditions: Multimodal Pain Management, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, enrollmentInfo count: 238, type: ESTIMATED, armsInterventionsModule interventions name: pain management, interventions name: ketoprofen, interventions name: PLacebo, outcomesModule primaryOutcomes measure: reduction in pain intensity during chest physiotherapy at 24 hours from the end of surgery, primaryOutcomes measure: NSAIDs reduce postoperative at rest at 24 hours from the end of surgery, secondaryOutcomes measure: Change in pain trajectory during the first 7 days after cardiac surgery, secondaryOutcomes measure: Change in cumulative opioid within 48 hours after surgery, secondaryOutcomes measure: Change in pulmonary postoperative complications within 7 days after surgery, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: CHU Amiens Picardie, status: RECRUITING, city: Amiens, country: France, contacts name: Osama ABOU ARAB, role: CONTACT, email: abouarab.osama@chu-amiens.fr, contacts name: Emmanuel BESNIER, MD, role: PRINCIPAL_INVESTIGATOR, contacts name: Mouhamed MOUSSA, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 49.9, lon: 2.3, hasResults: False
protocolSection identificationModule nctId: NCT06381050, orgStudyIdInfo id: SHR-7631-101, briefTitle: The Clinical Study of SHR-7631 for Injection in Patients With Advanced Solid Tumors, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2026-04, completionDateStruct date: 2027-04, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Suzhou Suncadia Biopharmaceuticals Co., Ltd., class: INDUSTRY, descriptionModule briefSummary: This study is an open-label, phase I clinical trial of SHR-7631 in patients with advanced solid tumors. The whole study is divided into three stages: dose escalation, dose expansion and efficacy expansion., conditionsModule conditions: Advanced Solid Tumors, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 150, type: ESTIMATED, armsInterventionsModule interventions name: SHR-7631, outcomesModule primaryOutcomes measure: Maximum tolerated dose (MTD) or maximum administered dose (MAD), primaryOutcomes measure: Incidence and severity of adverse events (AEs)/serious adverse events (SAEs) (CTCAE v5.0), secondaryOutcomes measure: PK parameter: Tmax, secondaryOutcomes measure: PK parameter: Cmax, secondaryOutcomes measure: PK parameter: AUC0-t, secondaryOutcomes measure: PK parameter: AUC0-∞, secondaryOutcomes measure: PK parameter: t1/2, secondaryOutcomes measure: PK parameter: MRT (mean residence time), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06381011, orgStudyIdInfo id: BEUFTR-4, briefTitle: Local Vibration in Cervical Radiculopathy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2024-06-01, completionDateStruct date: 2024-09-01, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Bitlis Eren University, class: OTHER, descriptionModule briefSummary: The aim of this study is to evaluate the effect of local vibration application on the upper extremity pain, paresthesia, neck pain, and limitations in cervical joint range of motion experienced by patients with cervical radiculopathy., conditionsModule conditions: Cervical Radiculopathy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: The evaluator and the researcher administering the local vibration application will be different. Patients will be blinded to their group assignment., whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 34, type: ESTIMATED, armsInterventionsModule interventions name: Local Vibration, outcomesModule primaryOutcomes measure: Neck Pain, primaryOutcomes measure: Upper Limb Pain, primaryOutcomes measure: Paresthesia, secondaryOutcomes measure: Cervical Range of Motion, secondaryOutcomes measure: The Change in the Pressure Pain Threshold of the Upper Trapezius, secondaryOutcomes measure: The Change in the Viscoelastic Properties of the Upper Trapezius, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Bitlis Eren University, city: Bitlis, state: Merkez, zip: 13000, country: Turkey, contacts name: Ömer Dursun, Asst. Prof., role: CONTACT, phone: 5426088687, phoneExt: +90, email: fztomrdrsn@gmail.com, contacts name: Erhan Dincer, M.Sc., role: CONTACT, phone: 5442543857, phoneExt: +90, email: fzterhan@hotmail.com, geoPoint lat: 38.40115, lon: 42.10784, hasResults: False
protocolSection identificationModule nctId: NCT06380998, orgStudyIdInfo id: EPCPHCFAPAEWPSPSWAG, briefTitle: Effects of Petroleum Compounds on Psychological Health and Cognitive Functions, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-10-01, primaryCompletionDateStruct date: 2025-10-01, completionDateStruct date: 2027-10-01, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: Over the last decade, awareness of the effects of hydrocarbon fuels on neurodegenerative disorders has increased significantly, as they are ubiquitous environmentally toxic chemicals that affect the central nervous system and result in irreversible neuronal damage, as many hydrocarbons can cross the blood-brain barrier through multiple pathways and cause direct toxicity., conditionsModule conditions: Cognitive Deterioration, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 196, type: ESTIMATED, armsInterventionsModule interventions name: whey protien, outcomesModule primaryOutcomes measure: Effects of petroleum compounds on psychological health and cognitive functions of petrol station workers in Assiut, primaryOutcomes measure: To explore the relation between the level of petroleum hydrocarbon metabolites and the severity of psychological heath and cognitive functions disturbance of petrol station workers, primaryOutcomes measure: To explore the role of supplements with whey protein in ameliorating these effects, secondaryOutcomes measure: To assess the relationship between the psychological effects, cognitive functions, and nutritional status of petroleum station workers, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule locations facility: Faculty of medicine, city: Assiut, state: Assiut University, zip: 71515, country: Egypt, geoPoint lat: 27.18096, lon: 31.18368, hasResults: False
protocolSection identificationModule nctId: NCT06380972, orgStudyIdInfo id: HDM6009A-301, briefTitle: A Prospective, Randomized, No-treatment Controlled, Evaluator-blinded Clinical Trial to Evaluate the Efficacy and Safety of Polycaprolactone Microspherical Injectable to Improve Forehead Contour, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2025-09, completionDateStruct date: 2025-10, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: AQTIS Medical B.V., class: OTHER, descriptionModule briefSummary: A Prospective, Multicenter, Randomized, No-treatment-controlled, Evaluator-blinded, Superiority Clinical Trial to Evaluate the Efficacy and Safety of Polycaprolactone Based Facial Injectable to Improve Forehead Contour, conditionsModule conditions: Forehead Contouring, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: the method of endpoint blind evaluation is adopted, that is, it's blinded for the evaluator., whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 189, type: ESTIMATED, armsInterventionsModule interventions name: Polycaprolactone (PCL) Based Facial Injectable, outcomesModule primaryOutcomes measure: The response rate for improving the forehead contour is assessed by the blinded investigator using the Asian Sloping Forehead Scale (ASFS), secondaryOutcomes measure: The response rate of forehead contour improvement assessed by blinded investigator using Asian Sloping Forehead Scale (ASFS), secondaryOutcomes measure: The response rate of forehead contour improvement assessed by injection investigator using Asian Sloping Forehead Scale (ASFS), secondaryOutcomes measure: The global aesthetic improvement rate assessed by the injection investigator based on the Global Aesthetic Improvement Scale (GAIS), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Guangdong Second Provincial General Hospital, city: Guangzhou, state: Guangdong, zip: 510317, country: China, contacts name: Shengkang Luo, role: CONTACT, phone: 02089168071, email: luoshengkang63@hotmail.com, contacts name: WEIJIN HONG, role: CONTACT, phone: 02089168071, contacts name: shengkang luo, role: PRINCIPAL_INVESTIGATOR, contacts name: weijin hong, role: SUB_INVESTIGATOR, geoPoint lat: 23.11667, lon: 113.25, hasResults: False
protocolSection identificationModule nctId: NCT06380959, orgStudyIdInfo id: 223K879, briefTitle: Art-based Activities in Stroke Patients, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-10-02, primaryCompletionDateStruct date: 2023-12-31, completionDateStruct date: 2024-02-29, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: Ege University, class: OTHER, descriptionModule briefSummary: Introduction and Aim: Life after stroke begins a difficult period in which functional capacity is very limited. Disability persists for a long time, and various problems such as hemiparesis, hemiplegia, dysarthria, dysphagia, urinary and bowel incontinence, which are frequently encountered after stroke, can affect the quality of life in the long term. As non-pharmacological approaches, especially non-invasive methods, have gained attention, creative arts-based therapies have often been recommended for stroke survivors because they have an arts-based approach without side effects. It is thought that the study conducted will contribute to the literature as there are not many studies in the literature. The aim of this study is to examine the effects of art-based activities on stroke patients' hope and self-efficacy levels. Its sub-purpose is to reveal the feelings and thoughts that arise with art objects obtained from art-based activities applied to stroke patients.Materials and Methods: The study was conducted as a randomised controlled design. After the groups were determined, art-based activities module was applied to the intervention group for one week, while no additional intervention was made to the control group. Research data were collected using "Individual Introduction Form", "Herth Hope Index", "Generalized Self-Efficacy Scale. Data were analyzed with Statistical Package for the Social Sciences 25.0 package program. Written permission was obtained from the relevant ethics committee, hospital and participants to conduct the study., conditionsModule conditions: Stroke, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomised Controlled, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 72, type: ACTUAL, armsInterventionsModule interventions name: Art Based Activity, outcomesModule primaryOutcomes measure: Herth Hope Index, primaryOutcomes measure: Generalized Self-Efficacy Scale, primaryOutcomes measure: Individual Introduction Form, secondaryOutcomes measure: Art Object Concretization Form, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ege University, city: Bornova, state: İzmir, zip: 35100, country: Turkey, geoPoint lat: 38.47921, lon: 27.2399, hasResults: False
protocolSection identificationModule nctId: NCT06380946, orgStudyIdInfo id: 978/91, briefTitle: Influence of Injectable Platelet Rich Fibrin on Different Orthodontic Tooth Movements During Clear Aligner Therapy, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2024-10-01, completionDateStruct date: 2024-11-01, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Al-Azhar University, class: OTHER, descriptionModule briefSummary: The aim of this prospective clinical project will be to assess the effect of platelet rich fibrin on the rate of different orthodontic tooth movements during clear aligner therapy., conditionsModule conditions: Effect of Platelet Rich FibrinDuring Clear Aligner Therapy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: FACTORIAL, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 78, type: ESTIMATED, armsInterventionsModule interventions name: iPRF, outcomesModule primaryOutcomes measure: Influence of injectable platelet rich fibrin rate of different orthodontic tooth movements by millimeter, eligibilityModule sex: ALL, minimumAge: 15 Years, maximumAge: 22 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: AlAzhar university, city: Cairo, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06380933, orgStudyIdInfo id: B11103008, briefTitle: The Effects of Receiving Warm Footbath With Lavender Essential Oil on Sleep and Comfort, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-09-01, primaryCompletionDateStruct date: 2022-09-01, completionDateStruct date: 2024-02-28, studyFirstPostDateStruct date: 2024-04-24, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Dalin Tzu Chi General Hospital, class: OTHER, descriptionModule briefSummary: Purposes: Describe the background information and clinical characteristics of respirator-dependent patients, verify the sleep and comfort effects of respirator-dependent patients whether or not they receive a lavender essential oil warm water foot bath, and compare changes of the sleep, comfort, heartbeat, and blood pressure in respirator-dependent patients before and after receiving a lavender essential oil warm water foot bath., conditionsModule conditions: Sleep Quality, conditions: Comfort, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: two-group crossover design trial and block randomly assigns groups after gender stratification. The experimental group first received a foot bath with lavender essential oil at 41-42C warm water for 20 minutes for 3 days, then rested for 3 days, and then received routine care for 3 days; the control group first received routine care for 3 days, then rested for 3 days, and then received lavender essential oil 41-42C warm water foot bath for 20 minutes for 3 days., primaryPurpose: PREVENTION, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 94, type: ACTUAL, armsInterventionsModule interventions name: experimental group, outcomesModule primaryOutcomes measure: Richards-Campbell Sleep Questionnaire, secondaryOutcomes measure: Numerical Rating of Comfort, eligibilityModule sex: ALL, minimumAge: 45 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hsu Mei-Lian, city: Chiayi City, country: Taiwan, geoPoint lat: 23.47917, lon: 120.44889, hasResults: False