hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06278987, orgStudyIdInfo id: ANES-2024-32661, briefTitle: Comparison of Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter in Patients With a Hip Fracture, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2026-06-01, completionDateStruct date: 2026-12-01, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: University of Minnesota, class: OTHER, descriptionModule briefSummary: The purpose of this study is to determine if patients with hip fractures who undergo cryoablation of the PENG have improved pain control 30 days from surgery when compared to those who have a fascia iliaca catheter., conditionsModule conditions: Hip Fractures, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: This is a randomized prospective controlled trial. This will be single blinded trial. Randomization will be 1:1, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 150, type: ESTIMATED, armsInterventionsModule interventions name: PENG block and cryoablation, interventions name: fascia iliaca compartment block, outcomesModule primaryOutcomes measure: Maximum pain score on Post-operative day 30, primaryOutcomes measure: Opioid use, primaryOutcomes measure: functional pain scores, primaryOutcomes measure: number of patients using opioids, primaryOutcomes measure: Length of Hospital Stay, primaryOutcomes measure: Time to first ambulation, primaryOutcomes measure: Number of patients returned home by Post Operative Day 30, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 85 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06278974, orgStudyIdInfo id: PDSFGOCLMC-2023-001, briefTitle: Comparing Myopia Treatments in Youth: Defocus Spectacles, Glasses, and Ortho-K, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-11-10, primaryCompletionDateStruct date: 2025-05-01, completionDateStruct date: 2025-05-01, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: He Eye Hospital, class: OTHER, descriptionModule briefSummary: The research project titled "A Comparative Study on the Clinical Efficacy, Quality of Life, and Cost of Use of Peripheral Defocus Spectacles, Frame Glasses, and Orthokeratology Lenses in Myopic Children and Adolescents" aims to evaluate different non-surgical myopia correction methods in children. It focuses on assessing the impact of peripheral defocus spectacles, frame glasses, and orthokeratology lenses on the quality of life, clinical effectiveness, and costs associated with each method. The study is a prospective cohort study involving 300 children aged 13-17 years with myopia ranging from -1.00D to -6.00D. It aims to compare the psychological, social, and educational aspects of these correction methods, alongside their costs and clinical outcomes over a period of one year., conditionsModule conditions: Myopia, conditions: Cost-effectiveness Analysis, conditions: Quality of Life, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 300, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Improvement in Quality of Life Scores, primaryOutcomes measure: Cost-Effectiveness Analysis, secondaryOutcomes measure: Clinical Effectiveness Analysis, eligibilityModule sex: ALL, minimumAge: 13 Years, maximumAge: 17 Years, stdAges: CHILD, contactsLocationsModule locations facility: HeEyeHospital, status: RECRUITING, city: Shenyang, state: Liaoning, zip: 110000, country: China, contacts name: Lan Hu, Master, role: CONTACT, phone: 15940406919, email: hulan@hsyk.com.cn, geoPoint lat: 41.79222, lon: 123.43278, hasResults: False
protocolSection identificationModule nctId: NCT06278961, orgStudyIdInfo id: IRB 2021-4329, briefTitle: Families Filming Infants Learning Movement, acronym: FILM, statusModule overallStatus: RECRUITING, startDateStruct date: 2021-01-28, primaryCompletionDateStruct date: 2024-09-30, completionDateStruct date: 2024-09-30, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Ann & Robert H Lurie Children's Hospital of Chicago, class: OTHER, collaborators name: Northwestern University, collaborators name: IRCCS Fondazione Stella Maris, collaborators name: University of Melbourne, collaborators name: University of Sydney, descriptionModule briefSummary: The study objective is to improve accuracy in the early detection of neurodevelopmental impairment, especially CP, by evaluating the timepoint (in weeks post term age) that the Prechtl GMA is most useful for prediction of neurodevelopmental impairment at two years of age in children with and without medical complexity. The study team plans to recruit 100 healthy, term-born infants and 250 infants at risk of developing CP for a total of 350 enrolled infants., conditionsModule conditions: Infant Development, conditions: Cerebral Palsy, conditions: Motor Disorders, conditions: Neurological Disorder, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 350, type: ESTIMATED, armsInterventionsModule interventions name: Observational, outcomesModule primaryOutcomes measure: Fidgety Movements in healthy, term born infants, primaryOutcomes measure: Fidgety Movements in children with a range of medical complexities, primaryOutcomes measure: Fidgety Movements and two-year Neurodevelopmental outcomes in health, term born infants, primaryOutcomes measure: Fidgety Movements and two-year Neurodevelopmental outcomes in children with a range of medical complexities, eligibilityModule sex: ALL, minimumAge: 10 Weeks, maximumAge: 20 Weeks, stdAges: CHILD, contactsLocationsModule locations facility: Feinberg School of Physical Therapy and Human Movement Sciences, status: RECRUITING, city: Chicago, state: Illinois, zip: 60611, country: United States, contacts name: Ryan Millman, B.S., role: CONTACT, phone: 847-530-2319, email: ryan.millman@northwestern.edu, geoPoint lat: 41.85003, lon: -87.65005, hasResults: False
protocolSection identificationModule nctId: NCT06278948, orgStudyIdInfo id: LRP23023-depigmenting cream, briefTitle: Efficacy and Tolerability of Test Product Versus Cysteamine 5% in Treatment of Facial Epidermal Melasma, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-10-06, primaryCompletionDateStruct date: 2024-06, completionDateStruct date: 2024-06, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Cosmetique Active International, class: INDUSTRY, descriptionModule briefSummary: This interventional, randomized, investigator blinded, controlled study conducted in one centre consists in a 4-month evaluation period within the same season avoiding sunny season on 140 subjects with facial epidermal melasma., conditionsModule conditions: Melasma, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 140, type: ESTIMATED, armsInterventionsModule interventions name: Group TP, interventions name: Group CYS, outcomesModule primaryOutcomes measure: change in mMASI scoring, primaryOutcomes measure: change in Investigator's Global Assessment (IGA), secondaryOutcomes measure: change in Subject Global Assessment of Improvement (SGAI), eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule locations facility: MS Clinical Research Pvt. Ltd, status: RECRUITING, city: Bangalore, country: India, geoPoint lat: 12.97194, lon: 77.59369, hasResults: False
protocolSection identificationModule nctId: NCT06278935, orgStudyIdInfo id: APP-24-00887, briefTitle: Lifestyle Tailored Offloading for Diabetic Foot Ulcers, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2026-04, completionDateStruct date: 2026-04, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-04-02, sponsorCollaboratorsModule leadSponsor name: University of Southern California, class: OTHER, descriptionModule briefSummary: The goal of this pilot clinical trial is to develop and test a tailored occupational therapist-led lifestyle-focused intervention to aid patients in improving diabetic foot ulcer care. The main questions it aims to answer are to determine the acceptability and feasibility of taking a tailored lifestyle-focused approach as part of comprehensive diabetic foot ulcer management. Patient participants with DFUs who require offloading treatment will receive the tailored lifestyle-focused self-management intervention., conditionsModule conditions: Diabetic Foot Ulcer, conditions: Diabetic Foot, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Lifestyle-based intervention by a occupational therapist, outcomesModule primaryOutcomes measure: Participant satisfaction, secondaryOutcomes measure: Diabetes distress, secondaryOutcomes measure: Factors affecting offloading treatment, secondaryOutcomes measure: DFU-related outcomes, eligibilityModule sex: ALL, minimumAge: 21 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06278909, orgStudyIdInfo id: 6036699, briefTitle: Trigeminal Nerve Stimulation in Treatment-resistant Generalized Anxiety Disorder: a Feasibility Study, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-18, primaryCompletionDateStruct date: 2025-01-30, completionDateStruct date: 2025-06-30, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-03-26, sponsorCollaboratorsModule leadSponsor name: Dr. Rafael Freire, class: OTHER, descriptionModule briefSummary: This is a feasibility study for trigeminal nerve stimulation (TNS) in patients with treatment-resistant generalized anxiety disorder (TR-GAD). Ten participants will receive TNS for 8 weeks as an augmentation strategy to pharmacological treatment for generalized anxiety disorder (GAD).* The primary objective is to ascertain if TNS is a safe and well-tolerated treatment for patients with TR-GAD.* The secondary objective will be to monitor changes in GAD symptom severity throughout the study.Results from this study will inform a randomized controlled trial to be conducted in the future., conditionsModule conditions: Generalized Anxiety Disorder, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: This is a traditional feasibility study, which evaluates preliminary safety and effectiveness information. It does not meet the definition of a "device feasibility" study., primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 10, type: ESTIMATED, armsInterventionsModule interventions name: Trigeminal Nerve Stimulation, outcomesModule primaryOutcomes measure: Incidence of treatment-emergent adverse events, primaryOutcomes measure: Incidence of treatment-emergent side effects measured with the NSEC, primaryOutcomes measure: Response to treatment defined by CGI-I score below 3, secondaryOutcomes measure: Remission defined by CGI-S score below 3, secondaryOutcomes measure: Change in anxiety severity measured by CGI-S, secondaryOutcomes measure: Change of anxiety symptoms measured with GAD-7, secondaryOutcomes measure: Change of anxiety symptoms measured with PSWQ, secondaryOutcomes measure: Change of anxiety symptoms measured with BAI, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Kingston Health Sciences Centre, status: RECRUITING, city: Kingston, state: Ontario, country: Canada, contacts name: Yan Deng, role: CONTACT, phone: +1-613-548-7839, email: yan.deng@queensu.ca, contacts name: Rafael Freire, MD PhD, role: PRINCIPAL_INVESTIGATOR, contacts name: Elisa Brietzke, MD PhD, role: SUB_INVESTIGATOR, contacts name: Claudio Soares, MD PhD, role: SUB_INVESTIGATOR, geoPoint lat: 44.22976, lon: -76.48101, hasResults: False
protocolSection identificationModule nctId: NCT06278896, orgStudyIdInfo id: 23-684-END, briefTitle: Early Neutropenic Fever De-escalation of Antibiotics Study, acronym: END, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2026-03-01, completionDateStruct date: 2028-03-01, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Brigham and Women's Hospital, class: OTHER, collaborators name: Dana-Farber Cancer Institute, descriptionModule briefSummary: This is a randomized, open label clinical trial among individuals with hematologic conditions. The trial aims to evaluate the safety and clinical outcomes of de-escalating antibiotic therapy among stable individuals diagnosed with neutropenic fever, in which no bacterial infection has been identified., conditionsModule conditions: Hematologic Malignancy, conditions: Febrile Neutropenia, conditions: Antibiotic Stewardship, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 260, type: ESTIMATED, armsInterventionsModule interventions name: Cessation of antibiotics, outcomesModule primaryOutcomes measure: Mortality, transfer to the ICU, septic shock, culture-confirmed bacteremia, primaryOutcomes measure: Antibiotic utilization, secondaryOutcomes measure: Mortality post F&N, secondaryOutcomes measure: Drug resistance, secondaryOutcomes measure: Clostridium difficile infection, secondaryOutcomes measure: Candidiasis, secondaryOutcomes measure: Adverse Events, secondaryOutcomes measure: Allergic Reactions, secondaryOutcomes measure: Bacteremia, secondaryOutcomes measure: Neutropenia, secondaryOutcomes measure: Length of stay, secondaryOutcomes measure: Readmissions, secondaryOutcomes measure: Fever, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06278844, orgStudyIdInfo id: 3020, briefTitle: Exercise Capacity Improvement by Conduction System Pacing in heArt Failure patieNts Without Compelling CRT inDication, acronym: ESCPAND, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-12-12, primaryCompletionDateStruct date: 2026-09, completionDateStruct date: 2027-12, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: University Hospital, Antwerp, class: OTHER, descriptionModule briefSummary: This randomized controlled trial aims to investigate the impact of conduction system pacing in comparison to right ventricular apical pacing on exercise capacity, as measured by peak oxygen uptake (VO2peak), in heart failure patients with indication for pacing but no compelling indication for cardiac resynchronization therapy (CRT). The mechanisms of exercise intolerance in heart failure patients influenced by conduction system pacing will be assessed., conditionsModule conditions: Heart Failure With Reduced Ejection Fraction, conditions: Heart Failure With Preserved Ejection Fraction, conditions: Heart Conduction Disorder, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 75, type: ESTIMATED, armsInterventionsModule interventions name: Conduction system pacing, interventions name: Right ventricular apical pacing, outcomesModule primaryOutcomes measure: Exercise capacity, secondaryOutcomes measure: Exercise capacity, secondaryOutcomes measure: Echocardiographic parameters (Ejection Fraction), secondaryOutcomes measure: QRS width, secondaryOutcomes measure: Biomarker, N-terminal pro B-type natriuretic peptide levels, secondaryOutcomes measure: Health-related quality of life scores, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Universitair Ziekenhuis Antwerpen, status: RECRUITING, city: Edegem, state: Antwerp, zip: 2650, country: Belgium, contacts name: Faro Verelst, role: CONTACT, phone: 038213538, email: faro.verelst@uza.be, geoPoint lat: 51.15662, lon: 4.44504, hasResults: False
protocolSection identificationModule nctId: NCT06278805, orgStudyIdInfo id: ayk22, briefTitle: Adaptation and Validation of the LUNS for Use in Turkey., statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-12-01, completionDateStruct date: 2025-02-01, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-04-11, sponsorCollaboratorsModule leadSponsor name: Uşak University, class: OTHER, collaborators name: Ankara University, collaborators name: Istanbul University, descriptionModule briefSummary: According to the most up-to-date knowledge, there is no Turkish comprehensive and validated instrument to assess stroke survivors' unmet needs in the longer term. So, this study aims to translate and adapt the LUNS into Turkish and examine its psychometric properties in survivors living at home after a stroke.Our hypothesis in this study is:- The Turkish Longer-term Unmet Needs after Stroke Questionnaire (T-LUNS) is a valid tool for assessing the unmet needs of stroke patients in the Turkish population., conditionsModule conditions: Stroke, conditions: Disability Physical, conditions: Quality of Life, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 110, type: ESTIMATED, armsInterventionsModule interventions name: The reliability and validity study of the T-LUNS, outcomesModule primaryOutcomes measure: The Turkish Longer-term Unmet Needs after Stroke Questionnaire (T-LUNS), primaryOutcomes measure: The Stroke Impact Scale 3.0 (SIS), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Usak, status: RECRUITING, city: Uşak, zip: 64200, country: Turkey, contacts name: Ali Y Karahan, role: CONTACT, phone: +905386921934, email: ali.karahan@usak.edu.tr, geoPoint lat: 38.67351, lon: 29.4058, hasResults: False
protocolSection identificationModule nctId: NCT06278792, orgStudyIdInfo id: Z-2021104, briefTitle: Readily Available Urinary Sodium Analysis in Patients With Acute Decompensated Heart Failure, acronym: EASY-HF, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-03-07, primaryCompletionDateStruct date: 2023-07-12, completionDateStruct date: 2024-01-05, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Ziekenhuis Oost-Limburg, class: OTHER, collaborators name: Fund for Scientific Research, Flanders, Belgium, descriptionModule briefSummary: The goal of this clinical trial is to compare physician-guided (SOC) versus nurse-led natriuresis-guided diuretic therapy in patients with acute decompensated heart failure (ADHF). The main questions it aims to answer are:* difference in natriuresis and diuresis* feasibility of the protocol.Participants will be asked to gather two 24 h urine collections.Researchers will compare SOC versus nurse-led diuretic titration to see if there is a difference in natriuresis after 48 hours., conditionsModule conditions: Acute Decompensated Heart Failure, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The EASY-HF study was a single-centre, randomized, open-label study comparing standard of care (SOC) diuretic management at the treating physician's discretion with a nurse-led natriuresis-guided protocol in patients with ADHF., primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: All physicians were blinded for the spot urinary sodium measurements. Additionally, while urine was collected for the first 48 h in both groups, the analysis was only performed afterwards., whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, enrollmentInfo count: 60, type: ACTUAL, armsInterventionsModule interventions name: Diuretic protocol, interventions name: Standard of Care, outcomesModule primaryOutcomes measure: Urinary sodium excretion after 48 hours, secondaryOutcomes measure: Urinary output after 48 hours, secondaryOutcomes measure: Urinary sodium excretion on daily base, secondaryOutcomes measure: Urinary output on daily base, secondaryOutcomes measure: Achievement of decongestion, otherOutcomes measure: Diuretic dose, otherOutcomes measure: User-friendliness device and protocol, otherOutcomes measure: Weight, otherOutcomes measure: Number of participants with need for heart failure rehospitalization, otherOutcomes measure: Rate of all-cause mortality, otherOutcomes measure: Length of hospital stay, otherOutcomes measure: Number of participants with severe hypotension, otherOutcomes measure: Number of participants with abnormal blood parameters, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ziekenhuis Oost-Limburg AV, city: Genk, state: Limburg, zip: 3600, country: Belgium, geoPoint lat: 50.965, lon: 5.50082, hasResults: False