protocolSection identificationModule nctId: NCT06384898, orgStudyIdInfo id: STUDY00002259, secondaryIdInfos id: UH3AT012413, type: OTHER_GRANT, domain: National Center for Complementary and Integrative Health, briefTitle: Remote Tai Chi for Knee Osteoarthritis, acronym: TAICHIKNEE, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09, primaryCompletionDateStruct date: 2026-12, completionDateStruct date: 2027-10, studyFirstPostDateStruct date: 2024-04-25, lastUpdatePostDateStruct date: 2024-04-25, sponsorCollaboratorsModule leadSponsor name: Tufts Medical Center, class: OTHER, collaborators name: Boston Medical Center, collaborators name: University of California, Los Angeles, collaborators name: The Cleveland Clinic, collaborators name: National Center for Complementary and Integrative Health (NCCIH), descriptionModule briefSummary: The goal of this pragmatic randomized trial is to evaluate the effectiveness of remote Tai Chi to treat knee pain in adults with knee osteoarthritis. The main questions the trial aims to answer are:* Does remote Tai Chi improve the extent to which pain interferes with physical, mental, and social activities (PROMIS-Pain Interference at 3 months, primary outcome), as well as knee pain and function (WOMAC subscales) and analgesic use (secondary outcomes)* Does remote tai chi decreases healthcare utilization?Researchers will compare remote Tai Chi added to routine care to routine care alone to see if remote tai chi works to treat knee osteoarthritis pain. Participants will participate in remotely delivered web-based tai chi sessions, twice a week for 12 weeks, or will continue to receive routine care. Participants will be followed for 12 months after randomization., conditionsModule conditions: Knee Osteoarthritis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The study is an individually randomized group-treatment (IRGT) trial. Individuals randomly allocated to remote Tai Chi receive the intervention with other participants through an instructor., primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: INVESTIGATOR, enrollmentInfo count: 480, type: ESTIMATED, armsInterventionsModule interventions name: Remote Tai Chi, outcomesModule primaryOutcomes measure: PROMIS Pain Interference score, primaryOutcomes measure: PROMIS Pain Interference score, primaryOutcomes measure: PROMIS Pain Interference score, secondaryOutcomes measure: WOMAC total score, secondaryOutcomes measure: WOMAC total score, secondaryOutcomes measure: WOMAC total score, secondaryOutcomes measure: SF-12 PCS score, secondaryOutcomes measure: SF-12 PCS score, secondaryOutcomes measure: SF-12 PCS score, secondaryOutcomes measure: Number of knee joint injections, otherOutcomes measure: WOMAC Pain Score, otherOutcomes measure: WOMAC Pain Score, otherOutcomes measure: WOMAC Pain Score, otherOutcomes measure: WOMAC Pain Score on nominated activity chosen at baseline, otherOutcomes measure: WOMAC Pain Score on nominated activity chosen at baseline, otherOutcomes measure: WOMAC Pain Score on nominated activity chosen at baseline, otherOutcomes measure: WOMAC function score, otherOutcomes measure: WOMAC function score, otherOutcomes measure: WOMAC function score, otherOutcomes measure: WOMAC stiffness score, otherOutcomes measure: WOMAC stiffness score, otherOutcomes measure: WOMAC stiffness score, otherOutcomes measure: Patient's global assessment score, otherOutcomes measure: Patient's global assessment score, otherOutcomes measure: Patient's global assessment score, otherOutcomes measure: PROMIS sleep disturbance OA Knee- Short Form 6a, otherOutcomes measure: PROMIS sleep disturbance OA Knee- Short Form 6a, otherOutcomes measure: PROMIS sleep disturbance OA Knee- Short Form 6a, otherOutcomes measure: Beck Depression Inventory-II score, otherOutcomes measure: Beck Depression Inventory-II score, otherOutcomes measure: Beck Depression Inventory-II score, otherOutcomes measure: SF-12 MCS score, otherOutcomes measure: SF-12 MCS score, otherOutcomes measure: SF-12 MCS score, otherOutcomes measure: Receipt of knee surgery, otherOutcomes measure: OMERACT/OARSI responder, otherOutcomes measure: OMERACT/OARSI responder, otherOutcomes measure: OMERACT/OARSI responder, otherOutcomes measure: Pain medication use, otherOutcomes measure: Pain medication use, otherOutcomes measure: Pain medication use, eligibilityModule sex: ALL, minimumAge: 50 Years, maximumAge: 100 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Tufts Medical Center, city: Boston, state: Massachusetts, zip: 02111, country: United States, contacts name: Sherwood Alexis, MHA, MBA, role: CONTACT, phone: 617-636-5405, email: sherwood.alexis@tuftsmedicalcenter.org, contacts name: Chenchen Wang, MD, role: PRINCIPAL_INVESTIGATOR, contacts name: Tim McAlindon, MD, role: SUB_INVESTIGATOR, geoPoint lat: 42.35843, lon: -71.05977, hasResults: False