protocolSection identificationModule nctId: NCT06261268, orgStudyIdInfo id: Strip vs FGG, briefTitle: Strip Graft w/ Xenogeneic Matrix vs Free Gingival Graft for the Augmentation of Peri-implant Keratinized Mucosa, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-29, primaryCompletionDateStruct date: 2024-12-15, completionDateStruct date: 2025-07-15, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-02-15, sponsorCollaboratorsModule leadSponsor name: Universidad Complutense de Madrid, class: OTHER, descriptionModule briefSummary: The primary objective of this study is to compare changes in peri-implant keratinized mucosa (PIKM) following the application of apically repositioned flap (ARF) using a combination of a Strip graft and a Xenogeneic matrix, or with a free gingival graft (FGG), in implants in the second stage with \<2 mm of PIKM.Additionally, as a secondary objective, the investigators compare postoperative blood supply in both recipient and donor sites based on the type of graft obtained. Meanwhile, the investigators evaluate differences between the two groups concerning microcirculation values (perfusion units, PU), soft tissue thickness (STT), volume change, vestibular depth, as well as clinical, aesthetic, and patient-reported outcome measures (PROMS)., conditionsModule conditions: Peri-Implantational Loss, conditions: Surgical Wound, conditions: Healing Surgical Wounds, conditions: Thin-gingiva, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: A randomized controlled equivalence clinical trial will be performed, with two parallel groups, a 1:1 allocation ratio, and a 12-month follow-up., primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 48, type: ESTIMATED, armsInterventionsModule interventions name: Strip graft with Mucograft, interventions name: Free gingival graft, outcomesModule primaryOutcomes measure: Changes in peri-implant keratinized mucosa width (mm), secondaryOutcomes measure: Vascularization (in Laser Speckle perfusion units [LSPU]), secondaryOutcomes measure: Changes in soft tissue thickness (STT) (mm), secondaryOutcomes measure: Vestibule depth (VD) (mm), secondaryOutcomes measure: Probing pocket depth (PPD) (mm), secondaryOutcomes measure: Dehiscence (mm), secondaryOutcomes measure: Full-mouth plaque score (FMPS), secondaryOutcomes measure: Volumetric changes, secondaryOutcomes measure: Patient reported outcome measures (PROMS), secondaryOutcomes measure: Esthetic analysis, secondaryOutcomes measure: Intra-surgical parameters, secondaryOutcomes measure: Intra-surgical time, secondaryOutcomes measure: Demographic data, secondaryOutcomes measure: Anamnesis data, secondaryOutcomes measure: Smoking habit, secondaryOutcomes measure: Full-mouth bleeding score (FMBS) (%), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Complutense University, status: RECRUITING, city: Madrid, zip: 28040, country: Spain, contacts name: Mariano Sanz Alonso, role: CONTACT, phone: 913942021, email: marsan@ucm.es, contacts name: Andrea Dobos, DMD, role: SUB_INVESTIGATOR, contacts name: David Palombo, DMD, role: SUB_INVESTIGATOR, geoPoint lat: 40.4165, lon: -3.70256, hasResults: False