protocolSection identificationModule nctId: NCT06334354, orgStudyIdInfo id: 23-320, briefTitle: A Study of Changes in Thinking Related to Aging and Cancer in Breast Cancer Survivors (TRAC), acronym: TRAC, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-19, primaryCompletionDateStruct date: 2029-03, completionDateStruct date: 2029-03, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-04-26, sponsorCollaboratorsModule leadSponsor name: Memorial Sloan Kettering Cancer Center, class: OTHER, descriptionModule briefSummary: The purpose of this study is to look at how differences in cognitive (mental) function develop over time in breast cancer survivors compared to volunteers without a history of cancer (healthy volunteers). Both cancer survivors and healthy volunteers (who are the same age as the cancer survivors) will participate in this study so the researchers can compare the results of neurocognitive testing (which looks at memory, attention, and information processing) on each group of participants., conditionsModule conditions: Breast Cancer Survivors, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 420, type: ESTIMATED, armsInterventionsModule interventions name: Assessments, interventions name: Assessment (Survivors Only), interventions name: APOE and DNA Isolation, outcomesModule primaryOutcomes measure: examine cognitive effects, secondaryOutcomes measure: measure levels of smoking exposure, eligibilityModule sex: FEMALE, minimumAge: 65 Years, maximumAge: 80 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Memorial Sloan Kettering Basking Ridge (All Protocol Activities), status: RECRUITING, city: Basking Ridge, state: New Jersey, zip: 07920, country: United States, contacts name: James Root, PhD, role: CONTACT, phone: 646-888-0035, geoPoint lat: 40.70621, lon: -74.54932, locations facility: Memorial Sloan Kettering Monmouth (All protocol activities), status: RECRUITING, city: Middletown, state: New Jersey, zip: 07748, country: United States, contacts name: James Root, PhD, role: CONTACT, phone: 646-888-0035, geoPoint lat: 40.39652, lon: -74.09211, locations facility: Memorial Sloan Kettering Bergen (All Protocol Activities), status: RECRUITING, city: Montvale, state: New Jersey, zip: 07645, country: United States, contacts name: James Root, PhD, role: CONTACT, phone: 646-888-0035, geoPoint lat: 41.04676, lon: -74.02292, locations facility: Memorial Sloan Kettering Suffolk - Commack (All Protocol Activities), status: RECRUITING, city: Commack, state: New York, zip: 11725, country: United States, contacts name: James Root, PhD, role: CONTACT, phone: 646-888-0035, geoPoint lat: 40.84288, lon: -73.29289, locations facility: Memorial Sloan Kettering Westchester (All Protocol Activities), status: RECRUITING, city: Harrison, state: New York, zip: 10604, country: United States, contacts name: James Root, PhD, role: CONTACT, phone: 646-888-0035, geoPoint lat: 40.96899, lon: -73.71263, locations facility: Memorial Sloan Kettering Cancer Center, status: RECRUITING, city: New York, state: New York, zip: 10065, country: United States, contacts name: James Root, PhD, role: CONTACT, phone: 646-888-0035, contacts name: Tim Ahles, PhD, role: CONTACT, phone: 646-888-0048, contacts name: James Root, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 40.71427, lon: -74.00597, locations facility: Memorial Sloan Kettering Nassau (All Protocol Activities), status: RECRUITING, city: Uniondale, state: New York, zip: 11553, country: United States, contacts name: James Root, PhD, role: CONTACT, phone: 646-888-0035, geoPoint lat: 40.70038, lon: -73.59291, hasResults: False