hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06289491, orgStudyIdInfo id: 2024P000544, briefTitle: Randomized Trial of Hydrus Microstent Versus Goniotomy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2027-04, completionDateStruct date: 2029-04, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Massachusetts Eye and Ear Infirmary, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to evaluate the comparative efficacy and safety of Hydrus Microstent, incisional goniotomy, and excisional goniotomy when combined with cataract surgery in patients with mild and moderate open-angle glaucoma. The main questions it aims to answer are:* How do the intraocular pressure lowering effects of these three microinvasive glaucoma surgeries compare?* How do the safety profiles of these three microinvasive glaucoma surgeries compare?Participants will be randomized to one of these three microinvasive glaucoma surgeries in combination with cataract surgery., conditionsModule conditions: Glaucoma, conditions: Glaucoma, Open-Angle, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 243, type: ESTIMATED, armsInterventionsModule interventions name: Hydrus Microstent, interventions name: Incisional goniotomy, interventions name: Excisional goniotomy, outcomesModule primaryOutcomes measure: Intraocular pressure, primaryOutcomes measure: Intraocular pressure-lowering medications, secondaryOutcomes measure: Surgical complications, eligibilityModule sex: ALL, minimumAge: 40 Years, maximumAge: 85 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06289478, orgStudyIdInfo id: 0151/67, briefTitle: Efficacy and Safety of Retrograde Intraarticular Injection Via Drain Tube, Topical Soaking of Tranexamic Acid (TXA), or Placebo in Elderly Patients With Femoral Neck Fractures Undergoing Cementless Bipolar Hemiarthroplasty - a Randomized Controlled Trial, acronym: TXA, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2026-04, completionDateStruct date: 2026-04, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: King Chulalongkorn Memorial Hospital, class: OTHER, descriptionModule briefSummary: The goal of this Randomized controlled trial is to evaluate in household ambulatory, elderly patients sustaining femoral neck fracture who are subjected to be treat with cementless bipolar hemiarthroplasty. The main questions it aims to answer are:* The efficacy in reducing blood transfusion for topical tranexamic acid administration* The safety of tranexemic acid, topically usedAs having undergone bipolar hemiarthroplasty surgery, participants will either receive retrograde intraarticular tranexamic acid injection via drain tube, or topical soaking administration.Researchers will compare, with standard procedure (procedure), whether topically administered tranexamic acid would reduce rate of blood transfusion., conditionsModule conditions: Femoral Neck Fracture, conditions: Bipolar Hemiarthroplasty, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 75, type: ESTIMATED, armsInterventionsModule interventions name: Topical tranexamic acid administration, outcomesModule primaryOutcomes measure: Rate of blood transfusion, secondaryOutcomes measure: Volume of blood transfusion, secondaryOutcomes measure: Calculated blood loss, secondaryOutcomes measure: Any adverse events, secondaryOutcomes measure: In-hospital mortality, eligibilityModule sex: ALL, minimumAge: 60 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Faculty of Medicine, city: Bangkok, zip: 10330, country: Thailand, contacts name: Kanyakorn Riewruja, role: CONTACT, phone: +66-95-864-4447, email: kanyakorn.riew@gmail.com, contacts name: Kanyakorn Riewruja, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 13.75398, lon: 100.50144, hasResults: False
protocolSection identificationModule nctId: NCT06289465, orgStudyIdInfo id: IstanbulBU, briefTitle: Examination of Pain, Posture, Physical and Mental Status in Seasonal Hazelnut Workers, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09-01, primaryCompletionDateStruct date: 2024-11-01, completionDateStruct date: 2024-12-01, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Istanbul Bilgi University, class: OTHER, descriptionModule briefSummary: The collection of hazelnuts grown in our country provides a great source of employment for local people and seasonal workers. However, geographical conditions in hazelnut growing areas, challenging variable weather conditions in August and insufficient number of workers create a disadvantageous environment for seasonal workers.In this study, it was aimed to investigate the effects of working conditions on mental status, fatigue, pain severity and postures (posture disorders, developmental delays, etc.) of young adults working in Giresun during the hazelnut picking season in comparison with the group living in the same sociodemographic and cultural environment but not working as seasonal workers., conditionsModule conditions: Agricultural Workers' Diseases, conditions: Posture, conditions: Pain, conditions: Depression, conditions: Fatigue, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Observation, outcomesModule primaryOutcomes measure: McGill Melzack Questionnaire, primaryOutcomes measure: PhysioPrint Mobile Application, primaryOutcomes measure: Checklist Individual Strength Questionnaire, secondaryOutcomes measure: Beck Depression Inventory, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 34 Years, stdAges: ADULT, contactsLocationsModule locations facility: Istanbul Bilgi University, city: Istanbul, zip: 34060, country: Turkey, contacts name: Furkan Çakır, M.Sc., role: CONTACT, phone: 2123115432, phoneExt: +90, email: furkan.cakir@bilgi.edu.tr, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06289452, orgStudyIdInfo id: IVB102-101, briefTitle: Safety and Efficacy Study of IVB102 Injection in Subjects With X-linked Retinoschisis, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-06, primaryCompletionDateStruct date: 2025-12-31, completionDateStruct date: 2029-12-31, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: InnoVec Biotherapeutics Inc., class: INDUSTRY, collaborators name: Peking Union Medical College Hospital, descriptionModule briefSummary: The goal of this clinical trial is to evaluate the safety and efficacy of IVB102 injection in subjects with XLRS., conditionsModule conditions: Retinoschisis, conditions: Retinal Disease, conditions: Retinal Degeneration, conditions: Eye Diseases, designModule studyType: INTERVENTIONAL, phases: EARLY_PHASE1, designInfo allocation: NON_RANDOMIZED, interventionModel: SEQUENTIAL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 18, type: ESTIMATED, armsInterventionsModule interventions name: IVB102 Injection, interventions name: IVB102 Injection, interventions name: IVB102 Injection, outcomesModule primaryOutcomes measure: Incidence of DLTs, primaryOutcomes measure: Incidence of AEs, primaryOutcomes measure: Incidence of SAEs, secondaryOutcomes measure: Visual function, secondaryOutcomes measure: OCT imaging, secondaryOutcomes measure: ERG parameters, eligibilityModule sex: MALE, minimumAge: 8 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Peking Union Medical College Hospital, city: Beijing, state: Beijing, zip: 100142, country: China, geoPoint lat: 39.9075, lon: 116.39723, hasResults: False
protocolSection identificationModule nctId: NCT06289426, orgStudyIdInfo id: KU3339, briefTitle: Online Yoga for Improving the Well-being of Desk-based Workers, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-15, primaryCompletionDateStruct date: 2024-08-15, completionDateStruct date: 2024-08-15, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Kingston University, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to evaluate the effectiveness of an 8-week online yoga intervention in improving the well-being and productivity of desk-based workers. The main questions it aims to answer are:* How effective is an 8-week online yoga intervention in improving the well-being (mental and physical) and productivity (work engagement and job performance) of the yoga group compared with passive controls?* Are there any differences in well-being and work-related measures between the yoga and control groups?Participants in the yoga group will practice yoga three days a week for 8 weeks and will be compared with a wait-listed control group, which will continue with the usual routine for 8 weeks. Researchers will evaluate the impact of yoga on the well-being and productivity of desk-based workers., conditionsModule conditions: Perceived Stress, conditions: Depression, conditions: Anxiety, conditions: Mindfulness, conditions: Self-Compassion, conditions: Compassion, conditions: Work Engagement, conditions: Productivity, conditions: Heart Rate Variability, conditions: Mental Wellbeing, conditions: Musculoskeletal Pain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Yoga, outcomesModule primaryOutcomes measure: Perceived Stress Scale, primaryOutcomes measure: PROMIS-Anxiety Short form, primaryOutcomes measure: The Short Warwick-Edinburgh Mental Well-being Scale (SWEMWBS), primaryOutcomes measure: The Mindful Attention Awareness Scale (MAAS), primaryOutcomes measure: The Cornell Musculoskeletal Discomfort Questionnaire (CMDQ), primaryOutcomes measure: Self-Compassion Scale Short Form (SCS-SF), primaryOutcomes measure: The Compassion Scale (CS), primaryOutcomes measure: Uterecht Work Engagment Scale-Short Form (UWES -9), primaryOutcomes measure: Work Ability Index (WAI), primaryOutcomes measure: Center for Epidemiologic Studies Short Depression Scale (CES-D-R 10), primaryOutcomes measure: Heart Rate Variability (HRV), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Vipin Wadhen, status: RECRUITING, city: London, zip: KT12EE, country: United Kingdom, contacts name: VIPIN WADHEN, MPhil, role: CONTACT, phone: 07308468129, email: V.Wadhen@kingston.ac.uk, geoPoint lat: 51.50853, lon: -0.12574, hasResults: False
protocolSection identificationModule nctId: NCT06289400, orgStudyIdInfo id: KaratayUOAS, briefTitle: Magnetic Field Application in Patellofemoral Pain Syndrome, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-26, primaryCompletionDateStruct date: 2024-05-01, completionDateStruct date: 2024-05-31, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: KTO Karatay University, class: OTHER, descriptionModule briefSummary: The purpose of this study is to examine the effect of magnetic field application used in the treatment of patellofemoral pain., conditionsModule conditions: Pain, Knee, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Magnetic field application, interventions name: Conventional treatment, outcomesModule primaryOutcomes measure: Visual Analogue Scale (VAS), primaryOutcomes measure: 36-Item Short Form Survey (SF-36), primaryOutcomes measure: Manual Muscle Test, primaryOutcomes measure: The Lower Extremity Functional Scale (LEFS), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: KTO Karatay University, status: RECRUITING, city: Konya, country: Turkey, contacts name: Osman Karaca, PhD, role: CONTACT, phone: +90 444 1251, phoneExt: 7845, email: osmankaracaftr@gmail.com, geoPoint lat: 37.87135, lon: 32.48464, hasResults: False
protocolSection identificationModule nctId: NCT06289374, orgStudyIdInfo id: 23HH8340, briefTitle: Longitudinal Assessment of Biomarkers After Oesophagogastric Cancer Surgery, acronym: LABS, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2028-06, completionDateStruct date: 2029-06, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Imperial College London, class: OTHER, collaborators name: Cancer Research UK, descriptionModule briefSummary: Oesophagogastric cancer (cancer of the gullet and stomach) is the fifth most common cancer in England and Wales with 16,000 new cases diagnosed every year. Survival rates are poor with only 15% surviving beyond 5 years. There is also increasing research to understand the cancer biology and factors allowing cancers to progress. It is likely there is a relationship between the cancer-specific microbiome, cells related to inflammation, which promotes cancer progression. The BIORESOURCE 1 study has established a comprehensive resource of matched samples from patients with oesophageal and gastric cancer. This longitudinal study aims to obtain further matched biosamples in the follow-up period after cancer surgery to find biomarkers that may predict treatment response, recurrence and/or long term prognosis., conditionsModule conditions: Oesophageal Adenocarcinoma, conditions: Gastric Adenocarcinoma, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Biosample collection, outcomesModule primaryOutcomes measure: Salivary microbial biomarkers to predict treatment response and long-term prognosis, secondaryOutcomes measure: Breath volatile organic compound profile alterations of oesophagogastric cancer pre- and post- treatment, secondaryOutcomes measure: Quality of life measure up to 2 years following cancer surgery using validated questionnaires, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 90 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Imperial College Healthcare NHS Trust, status: RECRUITING, city: London, country: United Kingdom, contacts name: Bhamini Vadhwana, role: CONTACT, contacts name: Professor George Hanna, PhD FRCS, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 51.50853, lon: -0.12574, hasResults: False
protocolSection identificationModule nctId: NCT06289348, orgStudyIdInfo id: APHP230240, secondaryIdInfos id: 2023-A00970-45, type: REGISTRY, domain: ID-RCB, briefTitle: Announcement of Rare Metabolic Diseases in Systematic Newborn Screening: the Phenylketonuria Experience., acronym: ANNPHE, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2027-04, completionDateStruct date: 2027-04, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Assistance Publique - Hôpitaux de Paris, class: OTHER, descriptionModule briefSummary: The aims of this collaborative, interdisciplinary research project are to understand and describe the psychological impact of the announcement of a rare, serious disease present since birth and detected in the context of the systematic neonatal screening (DNS), in terms of the parents' experience, but also on the part of the medical team, in order to improve its process and the support it provides for the announcement of the diagnosis., conditionsModule conditions: Phenylketonuria, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: socio-psychological questionnaire, interventions name: revised event impact scale (IER-S), interventions name: Non directive interview, interventions name: Stern interview, interventions name: semi-directive interview, outcomesModule primaryOutcomes measure: Psychological process linked to the announcement of inherited metabolic disease for the parents, primaryOutcomes measure: Psychological impact of the announcement of an inherited metabolic disease on the doctors' experience, primaryOutcomes measure: Measuring awareness of inherited metabolic diseases detected by midwives, secondaryOutcomes measure: Measure of the impact of the announcement on parents, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hôpital Necker Enfants Malades, city: Paris, zip: 75015, country: France, contacts name: Pascale DELONLAY, MD, PhD, role: CONTACT, phone: +33 1 44 49 48 52, email: pascale.delonlay@aphp.fr, geoPoint lat: 48.85341, lon: 2.3488, hasResults: False
protocolSection identificationModule nctId: NCT06289335, orgStudyIdInfo id: HCDrIMPrieto anaesthesia, briefTitle: Dexmedetomidine Compared to Ondansetron for Postanaesthetic Shivering in Patients Undergoing a Cesarean Section, statusModule overallStatus: COMPLETED, startDateStruct date: 2020-08-05, primaryCompletionDateStruct date: 2021-09-05, completionDateStruct date: 2022-01-03, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Hospital Central "Dr. Ignacio Morones Prieto", class: OTHER, descriptionModule briefSummary: Evaluate the efficiency of management with intravenous dexmedetomidine compared to intravenous ondansetron to achieve the disappearance of post-anesthetic shivering in a shorter time in the obstetric patient undergoing cesarean section under regional anesthesia., conditionsModule conditions: Postanesthetic Excitement, conditions: Cesarean Section, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 40, type: ACTUAL, armsInterventionsModule interventions name: saline solution, outcomesModule primaryOutcomes measure: Period of time, secondaryOutcomes measure: Adverse effects, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule locations facility: Hospital Central Dr. Ignacio Morones Prieto, city: San Luis Potosí, zip: 78290, country: Mexico, geoPoint lat: 22.14982, lon: -100.97916, hasResults: False
protocolSection identificationModule nctId: NCT06289322, orgStudyIdInfo id: EU101136769-CLIN1, briefTitle: AI4HOPE Dementia Pain Assessment Pilot Study 1, acronym: AI4HOPE1, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2025-07, primaryCompletionDateStruct date: 2026-12, completionDateStruct date: 2026-12, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-05, sponsorCollaboratorsModule leadSponsor name: University of Bonn, class: OTHER, collaborators name: University College Cork, collaborators name: University of Leeds, collaborators name: Fundacion Intras, collaborators name: Universidade do Porto, collaborators name: University Medical Centre Maribor, descriptionModule briefSummary: The pilot study will develop and test a standardized assessment toolkit that will provide conclusive information with a tolerable burden for cognitively impaired patients with dementia., conditionsModule conditions: Dementia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: Feasibility study, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 150, type: ESTIMATED, armsInterventionsModule interventions name: Digital toolkit for assessment, outcomesModule primaryOutcomes measure: Feasibility and acceptability of toolkit, primaryOutcomes measure: Accuracy of toolkit assessments, secondaryOutcomes measure: Effect of pain /distress interventions, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06289296, orgStudyIdInfo id: MCT, briefTitle: Medium Chain Fatty Acids and Ketones, acronym: MCFA, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-01-01, primaryCompletionDateStruct date: 2023-09-30, completionDateStruct date: 2023-09-30, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: University of Copenhagen, class: OTHER, descriptionModule briefSummary: 16 participants were randomized to complete two seven-day intervention periods with twice-daily consumption of Medium-chain fatty acids (MCT) or long-chain fatty acids (LCT) oil. Before and after each intervention, participants completed a five-hour experimental day evaluating the response to a first intake of the MCT or LCT oils (pre MCT or LCT), which was repeated after the intervention period of daily intake (post MCT or LCT) (Fig. The intervention periods were separated by a 2-4-week washout period., conditionsModule conditions: Diet, Healthy, conditions: Health, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: A parallel crossover design, in which a group of lean and a group of obese participants are allocated to complete two seven-day intervention periods with twice daily consumption of either medium-chain fatty acids or long-chain fatty acids., primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 16, type: ACTUAL, armsInterventionsModule interventions name: Fatty acid intake in lean and obese males, outcomesModule primaryOutcomes measure: Ketone bodies in plasma, eligibilityModule sex: MALE, minimumAge: 20 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule locations facility: University of Copenhagen, city: Copenhagen, zip: 2100, country: Denmark, geoPoint lat: 55.67594, lon: 12.56553, hasResults: False