protocolSection identificationModule nctId: NCT06290661, orgStudyIdInfo id: UHCT-IEC-SOP-016-03-01, briefTitle: Clinical Trial of the Safety and Efficacy of Peripheral Nerve Stimulation in the Treatment of Postherpetic Neuralgia., statusModule overallStatus: RECRUITING, startDateStruct date: 2023-02-09, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2025-06-30, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Wuhan Union Hospital, China, class: OTHER, collaborators name: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, collaborators name: The Second People's Hospital of GuangDong Province, collaborators name: Xiamen Hospital of Traditional Chinese Medicine, descriptionModule briefSummary: The goal of this clinical trial is to evaluate safety and efficacy of percutaneous peripheral nerve stimulation in patients with postherpetic neuralgia. The main questions it aims to answer are:1. The efficacy of percutaneous peripheral nerve stimulation in patients with postherpetic neuralgia2. The safety of percutaneous peripheral nerve stimulation in patients with postherpetic neuralgia Participants are going to undergo procedure that implant peripheral nerve stimulation electrode produced by Jiangsu CED Medtech Co., Ltd. Then the subjects, whose VAS scores decrease more 30% than baseline level, are classified into two groups randomly. One of the group receiving active stimulation called trial group and another receiving placebo stimulation called control group. All subjects are required to make their own subjects' pain diary to record VSA score before and after implantation until at the end of follow-up. Also, participants are asked to report use of analgesic medications, number of awakenings and adverse events.Researchers will compare pain scores between the two groups to see if peripheral nerve stimulation is effective to patients with postherpetic neuralgia., conditionsModule conditions: Neuropathic Pain, conditions: Postherpetic Neuralgia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Active electrostimulation, interventions name: Placebo electrostimulation, outcomesModule primaryOutcomes measure: Difference in mean pain visual analogue scale VAS scores between trial and control groups in the randomised withdrawal period, primaryOutcomes measure: Visual simulation assessment scale collects pain scores after peripheral electrode placement, secondaryOutcomes measure: Proportion of subjects whose pain relief more than 30%, secondaryOutcomes measure: Proportion of subjects of ideal pain state, secondaryOutcomes measure: Sleep-related assessment after electrostimulation, secondaryOutcomes measure: Change of life quality after electrostimulation, secondaryOutcomes measure: Analgesic medications, secondaryOutcomes measure: Stability of external assistant devices, secondaryOutcomes measure: Questionnaire survey equipment satisfaction, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Union Hospital, Tongji medical college, Huazhong University of Science and Technology, status: RECRUITING, city: Wuhan, state: Hubei, zip: 430022, country: China, contacts name: Dong Yang, PHD, role: CONTACT, phone: 13871230491, phoneExt: 86, email: dongyang118@sina.com, geoPoint lat: 30.58333, lon: 114.26667, hasResults: False