hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06338982, orgStudyIdInfo id: N-20230059, briefTitle: Fracture Pattern Following Bilateral Sagittal Split Osteotomy With or Without Impacted Third Molars, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-30, primaryCompletionDateStruct date: 2029-10-31, completionDateStruct date: 2030-10-31, studyFirstPostDateStruct date: 2024-04-01, lastUpdatePostDateStruct date: 2024-04-01, sponsorCollaboratorsModule leadSponsor name: Kimie Bols Østergaard, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to investigate the hypothesis that there are none difference in the treatment result of orthognathic surgery on the lower jaw, with interoperative wisdom tooth removal rather than preoperative wisdom tooth removal. In patients with severe dental malocclusion combined with a dentofacial deformity. The main question it aims to answer are:• Is there a difference in the degree of complication and the patient's perception, with inter-operative wisdom tooth removal rather than pre-operative wisdom tooth removal.Participants will be will be divided into two groups, with one group having their wisdom teeth removed 6 months before their jaw moving surgery and the other group having their wisdom teeth removed in connection with their jaw moving surgery., conditionsModule conditions: Impacted Third Molar Tooth, conditions: Osteotomy, conditions: Orthognathic Surgery, conditions: Mandibular Fractures, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized controlled trial with a test group and a control group., primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 150, type: ESTIMATED, armsInterventionsModule interventions name: Interoperative wisdom tooth removal in conjunction with BSSO, outcomesModule primaryOutcomes measure: Fracture pattern following BSSO with or without impacted third molars, primaryOutcomes measure: Condylar segment position following BSSO with or without impacted third molars, primaryOutcomes measure: Oral Health Impact Profile-14 (OHIP-14), primaryOutcomes measure: The Modified Dental Anxiety Scale (MDAS), primaryOutcomes measure: Short Form-36 (SF-36), primaryOutcomes measure: PROMs, secondaryOutcomes measure: Length of the surgical procedure, secondaryOutcomes measure: Intraoperative bleeding, secondaryOutcomes measure: Frequency of intra- and postoperative complications, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Aalborg universitets hospital, city: Aalborg, zip: 9000, country: Denmark, geoPoint lat: 57.048, lon: 9.9187, hasResults: False
protocolSection identificationModule nctId: NCT06338969, orgStudyIdInfo id: PostBariKetosis, briefTitle: The Impact of Different Carbohydrate Restriction After a Gastric Bypass on the Ketosis and Ketoacidosis, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-25, primaryCompletionDateStruct date: 2025-04-01, completionDateStruct date: 2025-08-01, studyFirstPostDateStruct date: 2024-04-01, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: The Society of Bariatric and Metabolic Surgeons of Kazakhstan, class: OTHER, descriptionModule briefSummary: Background:Ketosis after bariatric surgery is a metabolic process that occurs when the body breaks down fat for energy because of not getting enough carbohydrates.Insufficient production of ketone bodies reduces the rate of weight loss, and excessive amounts of ketones can lead to ketoacidosis or liver failure in patients with nonalcoholic steatohepatitis (NASH).The investigators hypothesize that weight loss is directly related to calorie intake, and a significant reduction in carbohydrate content leads to increased ketosis and the risk of ketoacidosis.Objectives:The study aimed to compare the incidence of ketoacidosis and liver failure in patients with NASH with different intakes of carbohydrates in the early postoperative period after gastric bypass. In addition, the investigators want to find out how carbohydrate restriction will affect weight loss for up to 1 year., conditionsModule conditions: Obesity, Morbid, conditions: NASH, conditions: Ketosis, conditions: Keto Acidosis, conditions: Carbohydrate Metabolism Disorder, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 150, type: ESTIMATED, armsInterventionsModule interventions name: Carbohydrate Restriction after a Gastric Bypass, outcomesModule primaryOutcomes measure: Cases of ketosis and incidence of ketoacidosis, primaryOutcomes measure: Cases of liver failure, secondaryOutcomes measure: Change in body mass index (Δ BMI), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Oral Ospanov, status: RECRUITING, city: Astana, state: Aqmola, zip: 010000, country: Kazakhstan, contacts name: Oral Ospanov, PhD, role: CONTACT, phone: 7015287734, phoneExt: +7, email: bariatric.kz@gmail.com, geoPoint lat: 51.1801, lon: 71.44598, hasResults: False
protocolSection identificationModule nctId: NCT06338956, orgStudyIdInfo id: Lipid-PCI, briefTitle: Optimal Attained LDL-Cholesterol Levels in Patients Who Achieved ≥50% LDL Reduction After PCI, acronym: Lipid-PCI, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-04-01, lastUpdatePostDateStruct date: 2024-04-01, sponsorCollaboratorsModule leadSponsor name: Samsung Medical Center, class: OTHER, descriptionModule briefSummary: For the management of low-density lipoprotein-cholesterol (LDL-C), some guidelines recommend initial statin treatment with high-intensity statins to achieve at least a 50% reduction in LDL-C levels. High-intensity or maximally tolerated intensity can be maintained without a target goal. However, the European guideline recommends less than 55 mg/dL of LDL-C after PCI., conditionsModule conditions: Coronary Artery Disease, conditions: Hyperlipidemias, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 94189, type: ESTIMATED, armsInterventionsModule interventions name: LDL reduction therapy, outcomesModule primaryOutcomes measure: MACCE, secondaryOutcomes measure: Cardiovascular death, secondaryOutcomes measure: Spontaneous myocardial infarction, secondaryOutcomes measure: Repeat revascularization, secondaryOutcomes measure: Ischemic stroke, eligibilityModule sex: ALL, minimumAge: 19 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Samsung Medical Center, status: RECRUITING, city: Seoul, country: Korea, Republic of, contacts name: Ki Hong Choi, MD, role: CONTACT, phone: 82-2-3410-3419, email: cardiokh@gmail.com, geoPoint lat: 37.566, lon: 126.9784, hasResults: False
protocolSection identificationModule nctId: NCT06338943, orgStudyIdInfo id: 02-02/24, briefTitle: Middle-aged Women With Adverse Pregnancy Outcomes and Heart Failure With Preserved Ejection Fraction, acronym: MAPO-HF, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-18, primaryCompletionDateStruct date: 2025-01, completionDateStruct date: 2025-01, studyFirstPostDateStruct date: 2024-04-01, lastUpdatePostDateStruct date: 2024-04-01, sponsorCollaboratorsModule leadSponsor name: National Medical Research Center for Therapy and Preventive Medicine, class: OTHER_GOV, descriptionModule briefSummary: Due to the steady increase in the burden of HFpEF, especially in women, it is an important task to search for new markers and early predictors associated with the development of this disease. Nowadays, the relationship of adverse pregnancy factors with the development of long-term cardiac pathology, in particular, HFpEF, has not been completely established. One of the most significant issue is studying the younger phenotype of women.The goal of this observational analytical cross-sectional study is to study the relationship of heart failure with a preserved ejection fraction in middle-aged women with adverse pregnancy outcomes in the history of pregnancy.Research question: is there an association between adverse pregnancy factors and the development of HF in middle-aged women?Objectives1. To assess the frequency of detection of APOs in the history of pregnancy in middle-aged women, depending on the presence or absence of HFpEF.2. To compare clinical and anamnestic data, morphological and functional parameters of the heart in middle-aged women with the presence and absence of HFpEF.3. To establish an association between APOs and the development of HFpEF in the long-term period in middle-aged women.4. To identify mediators between the presence of APOs and the development of HFpEF in middle-aged women.Study population - 45-60 year-old women with the history of pregnancy (\>20 weeks) in the absence of low left ventricle ejection fraction (\<50%)Primary endpoint: The prevalence of HFpEF in patients with the history of APOs., conditionsModule conditions: Heart Failure Preserved Ejection Fraction, conditions: Pregnancy Complications, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Echocardiography, interventions name: Questionnaire, outcomesModule primaryOutcomes measure: HFpEF incidence, primaryOutcomes measure: APOs incidence, eligibilityModule sex: FEMALE, minimumAge: 45 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: National Medical Research Center for Therapy and Preventive Medicine, status: RECRUITING, city: Moscow, country: Russian Federation, contacts name: Olga Dzhioeva, MD, PhD, role: CONTACT, phone: +79166141821, email: odzhioeva@gnicpm.ru, contacts name: Max Shperling, MD, role: PRINCIPAL_INVESTIGATOR, contacts name: Alexandr Mols, role: SUB_INVESTIGATOR, geoPoint lat: 55.75222, lon: 37.61556, hasResults: False
protocolSection identificationModule nctId: NCT06338878, orgStudyIdInfo id: 2023PI087, briefTitle: PAtient Treatment Analysis: Hospital and Wide-ranging Out-of-hospital Care Assessment Yields Insights Into Heart Failure Outcomes, acronym: PATHWAY-HF, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2027-01, completionDateStruct date: 2029-01, studyFirstPostDateStruct date: 2024-04-01, lastUpdatePostDateStruct date: 2024-04-01, sponsorCollaboratorsModule leadSponsor name: Pr. Nicolas GIRERD, class: OTHER, descriptionModule briefSummary: This is a monocentric cohort study conducted in the cardiology department of Nancy hospital. The main purpose of the study is to document the global management strategy of patients hospitalized for heart failure and evaluate the association between patient's care and post-hospitalization outcome., conditionsModule conditions: Heart Failure, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 1000, type: ESTIMATED, outcomesModule primaryOutcomes measure: All-cause post-hospitalization mortality, primaryOutcomes measure: Rehospitalization for heart failure, secondaryOutcomes measure: Percentage of maximum dose of each cardiotropic treatment indicated in heart failure according to ESC recommendations, secondaryOutcomes measure: Influenza and pneumococcal vaccination status, secondaryOutcomes measure: Evolution of renal function, secondaryOutcomes measure: All-cause Rehospitalization, secondaryOutcomes measure: All-cause mortality, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: CHRU de Nancy, status: RECRUITING, city: Nancy, country: France, contacts name: Laura FILIPPETTI, role: CONTACT, email: l.filippetti@chru-nancy.fr, geoPoint lat: 48.68439, lon: 6.18496, hasResults: False
protocolSection identificationModule nctId: NCT06338865, orgStudyIdInfo id: Study00003146, briefTitle: Short Title: Standard vs. Lower Pressure Pneumoperitoneum, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2027-04, completionDateStruct date: 2027-04, studyFirstPostDateStruct date: 2024-04-01, lastUpdatePostDateStruct date: 2024-04-01, sponsorCollaboratorsModule leadSponsor name: Cedars-Sinai Medical Center, class: OTHER, descriptionModule briefSummary: This study aims to investigate the effect of varying insufflation pressures on post-operative pain and adequacy of surgical field visualization among patients undergoing laparoscopic surgery with a minimally invasive gynecologic surgeon., conditionsModule conditions: Laparoscopic Surgery, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: DOUBLE, maskingDescription: Patients and post-anesthesia care unit nurses will be masked., whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 294, type: ESTIMATED, armsInterventionsModule interventions name: Carbon dioxide, interventions name: Bupivacaine, interventions name: Oxycodone, outcomesModule primaryOutcomes measure: Maximum documented pain score in post-anesthesia care unit (PACU) (numerical rating scale, 0-10), secondaryOutcomes measure: First reported pain score in PACU (numerical rating scale, 0-10), secondaryOutcomes measure: Last reported pain score in PACU prior to discharge (numerical rating scale, 0-10), secondaryOutcomes measure: Inpatient morphine milligram equivalents, secondaryOutcomes measure: Total number of 5mg oxycodone pills taken in the 2 weeks following discharge, secondaryOutcomes measure: Need for insufflation pressure increase intra-operatively due to inadequate visualization, secondaryOutcomes measure: Operative time, secondaryOutcomes measure: Estimated blood loss, secondaryOutcomes measure: Intraoperative complications, secondaryOutcomes measure: Conversion to laparotomy, secondaryOutcomes measure: Postoperative length of stay, secondaryOutcomes measure: Surgeon-reported adequacy of assigned insufflation pressure, secondaryOutcomes measure: Need for adjustment of insufflation pressure, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06338852, orgStudyIdInfo id: 4347, briefTitle: Awareness of Gynaecologists About Role of Physical Therapy in Genital Prolapse, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-03-03, primaryCompletionDateStruct date: 2023-06-03, completionDateStruct date: 2023-07-03, studyFirstPostDateStruct date: 2024-04-01, lastUpdatePostDateStruct date: 2024-04-01, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: The aim of this study will be to detect if there is awareness of gynecologists about the role of physical therapy in genital prolapse.Physical therapy plays an important role in assessment, prevention and treatment of pelvic floor dysfunction and genital prolapse, it helps to stimulate and strength pelvic floor muscle.Physical therapy treatments for the pelvic floor may include bladder training, pelvic floor muscles training with or without biofeedback, vaginal cones, electro stimulation or other adjuncts to training., conditionsModule conditions: Genital Prolapse, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: RETROSPECTIVE, enrollmentInfo count: 370, type: ACTUAL, armsInterventionsModule interventions name: Socio demographic and evaluation questionnaires, outcomesModule primaryOutcomes measure: Socio demographic and evaluation questionnaires, eligibilityModule sex: ALL, minimumAge: 29 Years, maximumAge: 44 Years, stdAges: ADULT, contactsLocationsModule locations facility: Faculty of physical therapy cairo university, city: Cairo, zip: 37617692, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06338813, orgStudyIdInfo id: Merve Unutmaz, briefTitle: Digital Manometry for Intra-Abdominal Pressure Measurement in Ileus, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-10-30, primaryCompletionDateStruct date: 2023-02-22, completionDateStruct date: 2023-03-01, studyFirstPostDateStruct date: 2024-04-01, lastUpdatePostDateStruct date: 2024-04-01, sponsorCollaboratorsModule leadSponsor name: Ankara City Hospital Bilkent, class: OTHER, descriptionModule briefSummary: Although many measurement techniques have been tried for intra-abdominal pressure, the Kron technique is currently the gold standard method. However, the search for other methods continues due to its long application time, the need for more equipment, and impracticality. Consequently, the investigators sought to investigate a quicker and more accessible method suitable for successful intra-abdominal pressure measurement in the emergency department. This study aimed to compare intra-abdominal pressure measurements in patients diagnosed with ileus using a digital manometer and the Kron Technique., conditionsModule conditions: Ileus, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: SCREENING, maskingInfo masking: TRIPLE, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 30, type: ACTUAL, armsInterventionsModule interventions name: Digital Manometry, outcomesModule primaryOutcomes measure: Digital manometer measuring for Intraabdominal Pressure, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 99 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ankara City Hospital, city: Ankara, zip: 06100, country: Turkey, geoPoint lat: 39.91987, lon: 32.85427, hasResults: False
protocolSection identificationModule nctId: NCT06338800, orgStudyIdInfo id: PSY-2324-S-0134, briefTitle: One Session Virtual Reality During Ongoing Treatment for Anxiety: Feasibility in Children and Adolescents, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-04, completionDateStruct date: 2025-12, studyFirstPostDateStruct date: 2024-04-01, lastUpdatePostDateStruct date: 2024-04-01, sponsorCollaboratorsModule leadSponsor name: Accare, class: OTHER, descriptionModule briefSummary: The goal of this study is to evaluate one session with exposure with Virtual Reality (VR) in in children and adolescents, aged 8-18 years with an anxiety disorder. The main questions it aims to answer are:1. What are the expectations of children and adolescents and therapists with VR exposure?2. What is the acceptability of the VR session (positive and negative effects)?3. What are possible working mechanisms of VR exposure? During ongoing treatment, participants will receive a session of exposure with VR., conditionsModule conditions: Anxiety Disorders, conditions: Exposure, conditions: Social Anxiety Disorder, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: During ongoing treatment for their anxiety disorder 30 children and adolescents (8-18 years) with an anxiety disorder will receive a session of exposure with VR. Before the session expectations of VR exposure will be assessed. Before and after the session willingness to participate in exposure in vivo will be measured. During the session anxiety, idiosyncratic expectations, and self-efficacy are measured. After the session, positive effects, experiences, and negative side effects will be asked for., primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: One session exposure with Virtual Reality, outcomesModule primaryOutcomes measure: Willingness to participate in exposure in vivo, secondaryOutcomes measure: Idiosyncratic expectations, secondaryOutcomes measure: Anxiety, secondaryOutcomes measure: Expectations of Virtual Reality, secondaryOutcomes measure: Acceptability, eligibilityModule sex: ALL, minimumAge: 8 Years, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06338787, orgStudyIdInfo id: 23-0826.2, briefTitle: A Novel Iron-Based Supplement for Athletes Aged 14-17, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2024-09, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-04-01, lastUpdatePostDateStruct date: 2024-04-01, sponsorCollaboratorsModule leadSponsor name: University of Calgary, class: OTHER, collaborators name: Mitacs, collaborators name: Natural Sciences and Engineering Research Council, Canada, descriptionModule briefSummary: Female endurance athletes are susceptible to iron deficiency and this can impact their exercise performance. This study aims to assess the efficacy of a novel iron supplement in improving iron status, gut microbiome, and exercise performance in endurance-trained females., conditionsModule conditions: Iron Deficiencies, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: FeSC, outcomesModule primaryOutcomes measure: Iron Status, primaryOutcomes measure: Hemoglobin, primaryOutcomes measure: Lower Gut microbiome, secondaryOutcomes measure: Exercise Capacity, otherOutcomes measure: Gastrointestinal Symptoms 1, otherOutcomes measure: Gastrointestinal Symptoms 2, otherOutcomes measure: Sleepiness, otherOutcomes measure: Stress and Recovery, eligibilityModule sex: FEMALE, minimumAge: 14 Years, maximumAge: 17 Years, stdAges: CHILD, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06338761, orgStudyIdInfo id: E-cigarette PCI, briefTitle: Switching to E-cigarette After PCI, acronym: E-cig-PCI, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-04-01, lastUpdatePostDateStruct date: 2024-04-01, sponsorCollaboratorsModule leadSponsor name: Samsung Medical Center, class: OTHER, descriptionModule briefSummary: Despite the increasing popularity of electronic cigarettes (E-cigarettes), the prognostic impact of switching to E-cigarettes in smokers with coronary artery disease (CAD) who underwent percutaneous coronary intervention (PCI) remains uncertain., conditionsModule conditions: Coronary Artery Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 17442, type: ESTIMATED, armsInterventionsModule interventions name: Smoking cessation, interventions name: Switching to E-cigarette, outcomesModule primaryOutcomes measure: MACE, secondaryOutcomes measure: Cardiovascular death, secondaryOutcomes measure: All-cause death, secondaryOutcomes measure: Spontaneous myocardial infarction, secondaryOutcomes measure: Repeat revascularization, eligibilityModule sex: ALL, minimumAge: 20 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Samsung Medical Center, status: RECRUITING, city: Seoul, country: Korea, Republic of, contacts name: Ki Hong Choi, MD, role: CONTACT, phone: 82-2-3410-3419, email: cardiokh@gmail.com, geoPoint lat: 37.566, lon: 126.9784, hasResults: False