hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06264193, orgStudyIdInfo id: Rowers, briefTitle: The Impact of Hypoxia on the Biochemical and Morphological Parameters of Blood in Rowers., acronym: IHOBMPBR, statusModule overallStatus: COMPLETED, startDateStruct date: 2014-11-30, primaryCompletionDateStruct date: 2014-12-21, completionDateStruct date: 2014-12-21, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-16, sponsorCollaboratorsModule leadSponsor name: Poznan University of Physical Education, class: OTHER, descriptionModule briefSummary: The response to hypoxia is very individual and epending on many aspects, such as the type of training, duration, intensity, or hypoxic stimulus, hypoxia affects the athlete in various ways. The results of this study have shown that 18 days of the LH-TL method does not significantly increase the level of EPO and VEGF in rowers. However, reticulocytes, immature red blood cells, have shown significant differences after 18-d LH-TL between groups. Further research should be carried out to investigate an optimal hypoxic dose and time, which will raise EPO, VEGF, and morphology variables., conditionsModule conditions: Hypoxia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: The hypoxic group included rowers participating in sports training and the LH-TL method, hypoxic rooms (FiO2=14.5%, corresponds to an altitude of 3000 meters). And the control group participating only in sports training and living in normoxic rooms, at the same sports camp., primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 13, type: ACTUAL, armsInterventionsModule interventions name: hypoxia, outcomesModule primaryOutcomes measure: Erythropoietin (EPO) mlU/ml, primaryOutcomes measure: vascular endothelial growth factor (VEGF) mlU/ml, secondaryOutcomes measure: creatine kinase (CK) ng/ml, secondaryOutcomes measure: Hs C-Reactive Protein (hsCRP) mg/L, secondaryOutcomes measure: hemoglobin (Hb)g/dL, secondaryOutcomes measure: hematocrit (Htc)%, secondaryOutcomes measure: red blood cells (RBC)mln/mm3, secondaryOutcomes measure: white blood cells (WBC)10 3/µL, secondaryOutcomes measure: reticulocytes (Ret)‰, secondaryOutcomes measure: SpO2 - oxygen saturation (%), secondaryOutcomes measure: bpm - beats per minute(%), eligibilityModule sex: MALE, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06264180, orgStudyIdInfo id: RP1-104, briefTitle: VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs (IGNYTE-3), statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2029-01-01, completionDateStruct date: 2034-08-31, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-16, sponsorCollaboratorsModule leadSponsor name: Replimune Inc., class: INDUSTRY, descriptionModule briefSummary: This is a randomized, controlled, multicenter, open-label Phase 3 clinical study comparing VO in combination with nivolumab versus Physician's Choice treatment for patients with unresectable Stage IIIb-IV cutaneous melanoma whose disease progressed on an anti PD-1 and an anti-CTLA-4 containing regimen (administered either as a combination regimen or in sequence) or who are not candidates for treatment with an anti-CTLA-4 therapy., conditionsModule conditions: Advanced Melanoma, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 400, type: ESTIMATED, armsInterventionsModule interventions name: Vusolimogene Oderparepvec, interventions name: Nivolumab, interventions name: Nivolumab + Relatlimab, interventions name: Pembrolizumab, interventions name: Single-agent chemotherapy, outcomesModule primaryOutcomes measure: Overall Survival (OS), secondaryOutcomes measure: Progression Free Survival (PFS), secondaryOutcomes measure: Objective Response Rate (ORR), eligibilityModule sex: ALL, minimumAge: 12 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06264154, orgStudyIdInfo id: 854051, secondaryIdInfos id: R01CA287474-01, type: NIH, link: https://reporter.nih.gov/quickSearch/R01CA287474-01, briefTitle: The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2027-06, completionDateStruct date: 2027-12, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-16, sponsorCollaboratorsModule leadSponsor name: University of Pennsylvania, class: OTHER, collaborators name: National Cancer Institute (NCI), descriptionModule briefSummary: This between-subjects study aims to evaluate the effect of flavor on initial and sustained switching from combustible cigarettes to e-cigarettes among 210 cigarette smokers. After measuring baseline cigarette smoking rate, participants will be randomized to a six-week regimen of fruit-flavored, tobacco-flavored, or menthol-flavored e-cigarettes and be instructed to switch (versus smoking cigarettes) over a 6-week period. Flavor-associated subjective reward and the reinforcing value of flavored e-cigarettes relative to combustible cigarettes will be assessed as mechanisms., conditionsModule conditions: Smoking, conditions: Tobacco Use, conditions: Cigarette Smoking, conditions: E-Cig Use, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: SINGLE_GROUP, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 210, type: ESTIMATED, armsInterventionsModule interventions name: E-cigarettes, outcomesModule primaryOutcomes measure: Cigarette Consumption, primaryOutcomes measure: Cigarette Smoking Behavior, eligibilityModule sex: ALL, minimumAge: 21 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06264128, orgStudyIdInfo id: TheraPAP Comfort, briefTitle: TPAP for Comfort in OSA, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-08, primaryCompletionDateStruct date: 2024-05-31, completionDateStruct date: 2024-06-30, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: SleepRes Inc., class: INDUSTRY, descriptionModule briefSummary: TheraPAP is a prototype device (with full documented electrical and isolation safety) being developed by SleepRes for the treatment of obstructive sleep apnea (OSA) that can deliver either standard CPAP at a set pressure or what is called TPAP . TPAP is a pressure control algorithm that lowers the pressure from the set pressure at the beginning of inspiration and does not return the pressure to the full set level until about halfway through expiration. The present study, TheraPAP Comfort, aims at assessing whether TPAP improves patient comfort vs. CPAP during supine wakefulness., conditionsModule conditions: Obstructive Sleep Apnea, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: All participants will undergo the same therapy combinations. CPAP (Continuous Positive Airway Pressure) and 2 level of TPAP (TheraPAP - novel CPAP approach pressure is reduced below therapy pressure from inspiration through mid exhalation specifically for comfort) will be assessed against each other in a round robin both backward and forward (6 total binary comparisons) for 2 levels of baseline pressure., primaryPurpose: TREATMENT, maskingInfo masking: NONE, maskingDescription: There is no specific intent to mask although participants will be naive to CPAP-type therapy, but they will be able to feel the difference., enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: TPAP, interventions name: CPAP, outcomesModule primaryOutcomes measure: CPAP v TPAP Patient Preference via Visual Analog Scale, secondaryOutcomes measure: TPAP 1 v TPAP 2 Patient Preference via Visual Analog Scale, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: SleepCenters of Middle Tennessee, status: RECRUITING, city: Murfreesboro, state: Tennessee, zip: 37129, country: United States, contacts name: Craig Salazar, role: CONTACT, phone: 615-893-4896, email: csalazar@sleepcenterinfo.com, contacts name: WIlliam H Noah, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 35.84562, lon: -86.39027, hasResults: False
protocolSection identificationModule nctId: NCT06264115, orgStudyIdInfo id: Soh-Med-24-01-05MS, briefTitle: Outcomes of Three Ports Versus Four Ports Laparoscopic Cholecystectomy, Sohag General Surgery Department Experience, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: Sohag University, class: OTHER, descriptionModule briefSummary: To compare the outcomes of three ports and four ports Laparoscopic Cholecystectomy, conditionsModule conditions: Cholecystitis, Chronic, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Laparoscopic Cholecystectomy, outcomesModule primaryOutcomes measure: Postoperative pain score, secondaryOutcomes measure: Operative time, secondaryOutcomes measure: length of hospital stay, otherOutcomes measure: Total postoperative morphine consumption, otherOutcomes measure: Time of first analgesic, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Sohag university, city: Sohag, country: Egypt, geoPoint lat: 26.55695, lon: 31.69478, hasResults: False
protocolSection identificationModule nctId: NCT06264102, orgStudyIdInfo id: 2024/1/1, briefTitle: Influence of Dalcroze Eurhythmics on Pains in Older Women, statusModule overallStatus: COMPLETED, startDateStruct date: 2019-01-11, primaryCompletionDateStruct date: 2019-03-08, completionDateStruct date: 2019-07-15, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-16, sponsorCollaboratorsModule leadSponsor name: Poznan University of Physical Education, class: OTHER, descriptionModule briefSummary: In this study, we attempted to answer the question of whether participation in a 12-week rhythmic exercise program using the Dalcroze method affects the level of intensity of pain experienced by women over the age of 65. The level of pain was determined on a numerical scale from 1 to 10 and involved headaches, back pain and leg pain., conditionsModule conditions: Back Pain, conditions: Headache, conditions: Leg Pain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 61, type: ACTUAL, armsInterventionsModule interventions name: Physical exercise program, outcomesModule primaryOutcomes measure: Pain levels before exercise program, secondaryOutcomes measure: Results of pain levels after exercise program, eligibilityModule sex: FEMALE, minimumAge: 65 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Poznan University of Physical Education, city: Poznań, state: Wielkopolska, zip: 61-871, country: Poland, geoPoint lat: 52.40692, lon: 16.92993, hasResults: False
protocolSection identificationModule nctId: NCT06264089, orgStudyIdInfo id: 202015, briefTitle: Effects of Preservation Rhinoplasty Nasal Valve Angle and Area, statusModule overallStatus: COMPLETED, startDateStruct date: 2020-08-06, primaryCompletionDateStruct date: 2023-08-30, completionDateStruct date: 2023-08-30, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-16, sponsorCollaboratorsModule leadSponsor name: Yuzuncu Yıl University, class: OTHER, descriptionModule briefSummary: The study planned to compare the internal nasal valve angle measurements of patients who underwent preservation rhinoplasty before and after surgery., conditionsModule conditions: Nasal Obstruction, Bilateral, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ACTUAL, armsInterventionsModule interventions name: Preservation Rhinoplasty Nasal Valve Angle and Area, outcomesModule primaryOutcomes measure: Nasal Obstruction Symptom Evaluation Scale (NOSE), secondaryOutcomes measure: Reformatted coronal Computed tomography, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Yaser Said Cetin, city: Van, zip: 65080, country: Turkey, geoPoint lat: 38.49457, lon: 43.38323, hasResults: False
protocolSection identificationModule nctId: NCT06264063, orgStudyIdInfo id: D-DIST, briefTitle: Study of Behavioral Dysfunctions and Related Neuronal Correlates in Patients With Dystonia, acronym: D-DIST, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-10, primaryCompletionDateStruct date: 2024-03-10, completionDateStruct date: 2025-10-10, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-16, sponsorCollaboratorsModule leadSponsor name: IRCCS Centro Neurolesi "Bonino-Pulejo", class: OTHER, descriptionModule briefSummary: Dystonias represent hyperkinetic movement disorders characterized by protracted muscle contractions, such as to cause torsional movements and anomalous postures in different parts of the body. Although they occur more often in a focal form (blepharospasm, oromandibular dystonia, cervical dystonia, laryngeal dystonia, attitudinal cramps of the limbs) than segmental (involvement of several contiguous muscle groups, e.g. facial muscles and neck muscles), they are nevertheless capable of significantly influencing the quality of life, with consequent social and health costs. Although described as a predominantly motor disorder, the presence of non-motor symptoms in dystonias associated with alteration of the fronto-striatal circuits is increasingly recognized. Neuroimaging studies have highlighted that the striatum and, more specifically, striatal dopamine, is involved in high cognitive processes such as attention, reward-based learning and decision making. Clinical conditions associated with cortico-striatal circuit dysfunction and abnormal meso-striatal or meso-cortical dopamine transmission also appear to influence temporal estimation, delay discounting, showing an impulsive preference for immediate rewards over delayed gratification.Based on these premises, the present project aims to evaluate the cognitive and affective aspects of dystonias, in line with neuroimaging research documenting structural and functional dysfunctions in the respective brain regions., conditionsModule conditions: Dystonia, conditions: Neurologic Disorder, conditions: NEUROSCIENCE, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SCREENING, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 102, type: ESTIMATED, armsInterventionsModule interventions name: control group, interventions name: experimental group, interventions name: EEG power in alpha band, outcomesModule primaryOutcomes measure: montreal cognitive assessment, primaryOutcomes measure: Beck depression inventory, secondaryOutcomes measure: EEG power in alpha band, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: IRCCS Centro Neurolesi Bonino Pulejo, status: RECRUITING, city: Messina, zip: 98124, country: Italy, contacts name: Caterina Formica, PhD, PSY, role: CONTACT, phone: +3909060128185, email: katia.formica@irccsme.it, geoPoint lat: 38.19394, lon: 15.55256, hasResults: False
protocolSection identificationModule nctId: NCT06264050, orgStudyIdInfo id: 2023.04, briefTitle: Psychological Support Group and Its Effects on Mood, Anxiety and Coping, acronym: SUPPORT, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2004-01-08, primaryCompletionDateStruct date: 2024-09-08, completionDateStruct date: 2025-03-15, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-16, sponsorCollaboratorsModule leadSponsor name: IRCCS San Camillo, Venezia, Italy, class: OTHER, descriptionModule briefSummary: The aim of this study is to verify the influence that participation in a Psychological Support Group has on anxiety, depression and coping skills in patients admitted to the IRCCS San Camillo Hospital.It is therefore an observational study with a pre-post design on a cohort of patients hospitalized at San Camillo IRCCS who attend the Psychological Support Group.The study consists of verifying whether the therapeutic activity of the Psychological Support Group (GSP) has an influence on the levels of anxiety, mood and coping skills in the patients who attend it. These purposes will be pursued through the administration to each patient at the beginning (pre) and at the end (post) of the period of attendance at the GSP, of validated scales: Stay Y2 (anxiety), BDI II(depressive symptoms), COPE NVD 25 (coping strategies) and the CORE-OM (outcomes of psychological activity)., conditionsModule conditions: Coping Strategies, conditions: Anxiety, conditions: Nurse-Patient Relations, conditions: Psychological, conditions: Mood Depressed, conditions: Rehabilitation, conditions: Neurologic Manifestations, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: pre post study on a single cohort, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 19, type: ACTUAL, armsInterventionsModule interventions name: evalutaion scales, outcomesModule primaryOutcomes measure: The State-Trait Anxiety Inventory (STAI) Y2, primaryOutcomes measure: The Beck Depression Inventory II (BDI-II), primaryOutcomes measure: The Clinical Outcomes in Routine Evaluation-Outcome Measure (CORE-OM), primaryOutcomes measure: The Coping Orientations to Problem Experienced NVI - 25, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 85 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06264037, orgStudyIdInfo id: 2023.03, secondaryIdInfos id: Studio 1574 /IRCCS San Camillo, type: OTHER, domain: CESC di Venezia e IRCSS San Camillo, briefTitle: The Experience in Neurorehabilitation Setting: a Qualitative Study, acronym: NURSEXPERIENCE, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-03-15, primaryCompletionDateStruct date: 2024-12-08, completionDateStruct date: 2025-03-15, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-16, sponsorCollaboratorsModule leadSponsor name: IRCCS San Camillo, Venezia, Italy, class: OTHER, descriptionModule briefSummary: In this exploratory qualitative study with a hermeneutic phenomenological approach, we will describe and understand the experience of treatment and hospitalization in hospitalized people suffering from stroke, multiple sclerosis, Parkinson\&#39;s disease and patients post-neurosurgery for oncological causes. Patients will be interviewed in a semi-structured manner and sampling will take place for each of the pathology groups according to the saturation method., conditionsModule conditions: Rehabilitation, conditions: Neurologic Disorder, conditions: Stroke, conditions: Parkinson Disease, conditions: Multiple Sclerosis, conditions: Neurosurgery, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: semi structured interview, outcomesModule primaryOutcomes measure: narrative contents, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Alberto Camuccio, status: RECRUITING, city: Venezia, zip: 30126, country: Italy, contacts name: Alberto Camuccio, doctor, role: CONTACT, phone: +39412207516, email: alberto.camuccio@hsancamillo.it, contacts name: Enrico Dal Pozzo, doctor, role: CONTACT, phone: +39412207111, email: enrico.dalpozzo@hsancamillo.it, geoPoint lat: 45.43713, lon: 12.33265, locations facility: IRCCS San Camillo Department of Neurorehabilitation, Venezia, status: RECRUITING, city: Venezia, zip: 30126, country: Italy, contacts name: Alberto Camuccio, doctor, role: CONTACT, phone: +39412207516, email: alberto.camuccio@hsancamillo.it, contacts name: Enrico Dal Pozzo, doctor, role: CONTACT, phone: +39412207111, email: enrico.dalpozzo@hsancamillo.it, geoPoint lat: 45.43713, lon: 12.33265, locations facility: IRCCS San Camillo Venezia, status: RECRUITING, city: Venezia, zip: 30126, country: Italy, contacts name: Alberto Camuccio, doctor, role: CONTACT, phone: +39412207516, email: alberto.camuccio@hsancamillo.it, contacts name: Enrico Dal Pozzo, doctor, role: CONTACT, phone: +39412207111, email: enrico.dalpozzo@hsancamillo.it, geoPoint lat: 45.43713, lon: 12.33265, hasResults: False