hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06316791, orgStudyIdInfo id: HY001007, briefTitle: Exploratory Clinical Study of CNCT19 Anti CD19 Cell Therapy in the Treatment of Refractory Autoimmune Diseases, statusModule overallStatus: RECRUITING, startDateStruct date: 2021-12-14, primaryCompletionDateStruct date: 2024-12-13, completionDateStruct date: 2025-12-13, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Juventas Cell Therapy Ltd., class: INDUSTRY, descriptionModule briefSummary: Exploratory clinical study of CNCT19 anti CD19 cell therapy in the treatment of refractory autoimmune diseases,To evaluate the safety and tolerability of CNCT19 in patients with refractory systemic lupus erythematosus (lupus nephritis, immune thrombocytopenia), refractory ANCA-associated vasculitis, and refractory dermatomyositis on the basis of standard of care., conditionsModule conditions: Lupus Erythematosus, Systemic, designModule studyType: INTERVENTIONAL, phases: EARLY_PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 24, type: ESTIMATED, armsInterventionsModule interventions name: single dose of CNCT19, outcomesModule primaryOutcomes measure: Percentage of Subjects Experiencing Treatment-Emergent Adverse Events（TEAE）, secondaryOutcomes measure: Overall survival (OS), secondaryOutcomes measure: SELENA-SLEDAI, secondaryOutcomes measure: The proportion of subjects who achieved glucocorticoids/immunosuppressant free and subjects who achieved low-dose glucocorticoids application during the main study period, secondaryOutcomes measure: To evaluate disease related biomarkers, secondaryOutcomes measure: To evaluate disease related biomarkers, secondaryOutcomes measure: To evaluate disease related biomarkers, secondaryOutcomes measure: To evaluate disease related biomarkers, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The First Affiliated Hospital of Zhengzhou University, status: RECRUITING, city: Zhengzhou, state: Henan, country: China, contacts name: Yi Zhang, Dr., role: CONTACT, contacts name: Shengyun Liu, Dr., role: CONTACT, geoPoint lat: 34.75778, lon: 113.64861, hasResults: False
protocolSection identificationModule nctId: NCT06316765, orgStudyIdInfo id: 118/10, briefTitle: A Stylet Use May be Beneficial for Elective and Rescue Intubation of Prematurely Born Infants, statusModule overallStatus: COMPLETED, startDateStruct date: 2016-01-01, primaryCompletionDateStruct date: 2022-12-31, completionDateStruct date: 2022-12-31, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Charles University, Czech Republic, class: OTHER, descriptionModule briefSummary: Contrary to recent findings suggesting that stylets offer no advantage in general infant intubations, this study focuses on their potential benefits for premature infants undergoing elective or rescue intubation in the delivery room. The goal is to compare the safety and efficiency of intubations with or without a stylet., conditionsModule conditions: Neonatology, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 70, type: ACTUAL, armsInterventionsModule interventions name: Intubation with stylet, outcomesModule primaryOutcomes measure: The primary outcome was defined as successful initial intubation attempt., secondaryOutcomes measure: Secondary outcomes was defined as the duration of intubation courses until successful placement of the endotracheal tube., eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06316752, orgStudyIdInfo id: 202107158RINB, briefTitle: The Natural History of Sialidosis Type I, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-03-15, primaryCompletionDateStruct date: 2024-03-16, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: National Taiwan University Hospital, class: OTHER, descriptionModule briefSummary: Sialidosis type 1 is an autosomal recessive disorder caused by bialleic NEU1 gene mutations. Patients with sialidosis type I present variable neurological and eye dysfunction and the progression rate is variable. The goal of this protocol is to assess the neurological and ophthalmological status of these patients and characterize the clinical and laboratory abnormalities in order to determine the natural history of the disease. Patients will be followed every 6 month with comprehensive clinical, neurological and ophthalmological examinations combined with neuropsychological, blood, radiological and electrophysiological tests., conditionsModule conditions: Observational Study, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Observational study, outcomesModule primaryOutcomes measure: Scale for the Assessment and Rating of Ataxia (SARA), primaryOutcomes measure: Unified Myoclonus Rating Scale (UMRS), secondaryOutcomes measure: MRI of the brain, secondaryOutcomes measure: Blood test for alpha-N -acetyl neuraminidase activity and neruofilamment light chain, secondaryOutcomes measure: Electrophysyiology test on peripheral nerves, secondaryOutcomes measure: Opathalmology examinations for cherry-red spots, secondaryOutcomes measure: Montreal cognitive assessment score, eligibilityModule sex: ALL, minimumAge: 12 Years, maximumAge: 80 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: National Taiwan University Hospital, status: RECRUITING, city: Taipei, zip: 100, country: Taiwan, contacts name: Chin-Hsien Lin, MD, PhD, role: CONTACT, phone: 882-23123456, email: chlin@ntu.edu.tw, contacts name: Wuh-Liang Hwu, MD, PhD, role: CONTACT, geoPoint lat: 25.04776, lon: 121.53185, hasResults: False
protocolSection identificationModule nctId: NCT06316726, orgStudyIdInfo id: 202100409A3, briefTitle: The Effectiveness of Two Nursing Programs on the Surgery-related Pressure Injury, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-12-15, primaryCompletionDateStruct date: 2023-08-31, completionDateStruct date: 2023-08-31, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Chang Gung Memorial Hospital, class: OTHER, descriptionModule briefSummary: Introduction: This study was to compare the differences in the incidence, grade, and time of surgery-related pressure injuries between the two interventions; and describe the locations of surgery-related pressure injuries between the two interventions.Methods: This study adopted a true experimental research design with a convenience sampling method from the operating rooms of a teaching hospital in a northern region. The experimental group was randomly assigned by block to receive intervention A (full bed silicone mattress plus other measures), and the control group received intervention B (full bed silicone mattress plus usual care). Measurements include basic personal attributes, risk factors, grade, time, and location of occurrence related to surgery-related pressure injuries., conditionsModule conditions: Pressure Injury, conditions: Surgery, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The experimental group was randomly assigned by block to receive intervention A (full bed silicone mattress plus other measures), and the control group received intervention B (full bed silicone mattress plus usual care)., primaryPurpose: PREVENTION, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 461, type: ACTUAL, armsInterventionsModule interventions name: full bed silicone mattress plus other measures, outcomesModule primaryOutcomes measure: the occurrence of surgery-related pressure injuries, eligibilityModule sex: ALL, minimumAge: 20 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Taoyuan Chang Gung Memorial Hospital, city: Taoyuan, zip: 333, country: Taiwan, geoPoint lat: 24.95233, lon: 121.20193, hasResults: False
protocolSection identificationModule nctId: NCT06316713, orgStudyIdInfo id: IRB_00166637, briefTitle: One MORE for Chronic Pain in Latinos, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-08, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: University of Utah, class: OTHER, descriptionModule briefSummary: This study will be a single-site, two-arm randomized controlled trial conducted among Spanish-speaking chronic pain patients. Chronic pain patients will be randomized by a computer-generated randomization schedule with simple random allocation (1:1) to either One MORE or a wait-list control condition (WLC). One MORE will be delivered individually either in-person or via a HIPAA compliant virtual meeting platform., conditionsModule conditions: Chronic Pain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 34, type: ESTIMATED, armsInterventionsModule interventions name: One MORE (Spanish Adaptation), outcomesModule primaryOutcomes measure: Pain Intensity & Interference, secondaryOutcomes measure: Acute Pain, secondaryOutcomes measure: Acceptability, otherOutcomes measure: Pain Catastrophizing, otherOutcomes measure: Well-Being, otherOutcomes measure: Depression, otherOutcomes measure: Anxiety, otherOutcomes measure: Mindful Reappraisal of Pain Sensations, otherOutcomes measure: Trait Self-Transcendence, otherOutcomes measure: Decentering, otherOutcomes measure: State Self-Transcendence, otherOutcomes measure: State Anxiety, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Utah, status: RECRUITING, city: Salt Lake City, state: Utah, zip: 84112, country: United States, contacts name: Eric Garland, PhD, role: CONTACT, phone: 801-581-3826, email: eric.garland@socwk.utah.edu, geoPoint lat: 40.76078, lon: -111.89105, hasResults: False
protocolSection identificationModule nctId: NCT06316700, orgStudyIdInfo id: AG-02-0124, briefTitle: A Pharmacokinetic Study of a Novel Nutritional Product on Healthy Men and Women, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-07-31, completionDateStruct date: 2024-10-01, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Athletic Greens International, class: INDUSTRY, descriptionModule briefSummary: This study is a randomized, double-blind, placebo-controlled study of N=16 apparently healthy men and women. The purpose of this study is to examine the bioavailability of a health and wellness supplement., conditionsModule conditions: Healthy Aging, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 16, type: ESTIMATED, armsInterventionsModule interventions name: Nutritional supplement, interventions name: Placebo, outcomesModule primaryOutcomes measure: Plasma concentration of zinc following consumption of study products, primaryOutcomes measure: Plasma concentration of Vitamin C following consumption of study products, primaryOutcomes measure: Plasma concentration of Folate following consumption of study products, primaryOutcomes measure: Plasma concentration of calcium following consumption of study products, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule locations facility: Center for Applied Health Sciences, city: Canfield, state: Ohio, zip: 44046, country: United States, geoPoint lat: 41.02506, lon: -80.76091, hasResults: False
protocolSection identificationModule nctId: NCT06316687, orgStudyIdInfo id: prevalence of dental caries, briefTitle: Prevalence of Dental Caries in a Group of Egyptian Children, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2024-09-01, completionDateStruct date: 2024-12-01, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: Prevalence of Dental Caries in a group of Egyptian children and its relation to TV and other screens time and sugar consumption (Observational cross-sectional study), conditionsModule conditions: Prevalence of Dental Caries and Its Relation to Screen Time and Sugar Consumption, conditions: Prevalence,Patient, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 296, type: ESTIMATED, armsInterventionsModule interventions name: questionnaire for food consumption frequency, outcomesModule primaryOutcomes measure: Prevalence of dental caries, secondaryOutcomes measure: Dental neglect Dental neglect Dental neglect, secondaryOutcomes measure: Screen time evaluation, secondaryOutcomes measure: A sugar consumption evaluation, eligibilityModule sex: ALL, minimumAge: 6 Years, maximumAge: 8 Years, stdAges: CHILD, contactsLocationsModule locations facility: Cairo University, city: Cairo, state: Al Manial, country: Egypt, contacts name: rasha ad el, phd, role: CONTACT, phone: 00201111511145, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06316674, orgStudyIdInfo id: 03C304, briefTitle: The Malleability of Body Representation in Anorexia Nervosa: the Sixth Finger Illusion, acronym: SESTODITO_AN, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-05-01, primaryCompletionDateStruct date: 2024-04-30, completionDateStruct date: 2024-04-30, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Istituto Auxologico Italiano, class: OTHER, collaborators name: Heriot-Watt University, collaborators name: Birkbeck, University of London, collaborators name: Catholic University of the Sacred Heart, descriptionModule briefSummary: Body representation can be explored using behavioural tasks such as motor imagery tasks as well as body illusions.In both cases, evidence from studies on healthy individuals as well as patients with lesions to the central nervous system show that body representation is not set in stone: how we imagine our bodies is a dynamic and continuously updated process, to reflect changes in our own body as well as the environment.In anorexia nervosa the representation of the body is very different from that of healthy individuals: the representation is more malleable, and easier to manipulate, while at the same time being more detached from physical constraints. These features of body representation in anorexia nervosa might contribute to the persistence of symptoms and to relapses too. Body representation has clear implications for treatment of anorexia nervosa too.The study aims at evaluating the presence of differences in the malleability of the body representation, explored through the illusion of the sixth finger, between a group of people with AN and a group of normal weight people, taking into account the biomechanical constraints that characterize the physical and mentally represented body., conditionsModule conditions: Anorexia Nervosa, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: sixth finger illusion, outcomesModule primaryOutcomes measure: Sixth finger illusion questionnaire, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule locations facility: Istituto Auxologico italiano IRCSS, status: RECRUITING, city: Milan, country: Italy, contacts name: Federico Brusa, Ph.D, role: CONTACT, email: f.brusa@auxologico.it, geoPoint lat: 45.46427, lon: 9.18951, hasResults: False
protocolSection identificationModule nctId: NCT06316661, orgStudyIdInfo id: 09C921, briefTitle: CMR Assessment of Cardiac Microvascular Dysfunction in Patients With HFpEF, acronym: MAPPED, statusModule overallStatus: RECRUITING, startDateStruct date: 2019-03-01, primaryCompletionDateStruct date: 2024-12-30, completionDateStruct date: 2024-12-30, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Istituto Auxologico Italiano, class: OTHER, descriptionModule briefSummary: Heart failure with preserved ejection fraction (HFpEF) causes hospitalizations, premature mortality and high health care costs. This is also due to poor understanding of HFpEF pathogenesis and, thus, lack of specific therapies. Prompted by the recent demonstration that HFpEF clusters different clinical phenotypes, the investigators propose that these phenogroups are driven by distinct myocardial abnormalities. Cardiac Magnetic Resonance (CMR) can help filling this gap in knowledge: on top of providing gold standard measurements for myocardial volume and cellular mass, recent technical advantages mean that this test can assess and quantify left ventricular extracellular volume, fibrosis and microvascular function accurately and non-invasively. In HFpEF patients, the investigators aim at assessing 1) the coronary microvascular function impairment; 2) the myocardial fibrotic burden; - seeking to understand the disease in order to improve care and cardiovascular outcomes for these patients., conditionsModule conditions: Microvascular Coronary Artery Disease, conditions: Heart Failure With Reduced Ejection Fraction, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: stress perfusion cardiac magnetic resonance, interventions name: cardiopulmonary exercise test, outcomesModule primaryOutcomes measure: Peak stress perfusion, primaryOutcomes measure: Extracellular volume, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: IRCCS Istituto Auxologico Italiano, status: RECRUITING, city: Milan, zip: 20149, country: Italy, contacts name: Camilla Torlasco, role: CONTACT, phone: +390261911, phoneExt: 2932, email: c.torlasco@auxologico.it, geoPoint lat: 45.46427, lon: 9.18951, hasResults: False
protocolSection identificationModule nctId: NCT06316648, orgStudyIdInfo id: 210366, briefTitle: Whey Intake Blood Glucose, Fasting, Thirst, Nausea and Vomiting Levels of Patients Undergoing Elective Hip Fracture Surgery, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-04-20, primaryCompletionDateStruct date: 2021-04-20, completionDateStruct date: 2021-07-20, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: TC Erciyes University, class: OTHER, descriptionModule briefSummary: Whey Intake Blood Glucose, Fasting, Thirst, Nausea, Vomiting Elective Hip Fracture Surgery, conditionsModule conditions: Elective Hip Fracture Surgery, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Multidisciplinary cooperation was performed for the effective and efficient conduct of the study. In determining the patients to administer Whey according to the study's inclusion criteria, an orthopedic and traumatological specialist's support was received, as well as that of an anesthesiologist. On the other hand, the researcher cooperated with a nutritionist in preparing and assessing the Whey content to be administered to the patients., primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ACTUAL, armsInterventionsModule interventions name: whey intake group, interventions name: control group, outcomesModule primaryOutcomes measure: blood glucose, secondaryOutcomes measure: Fasting, Thirst, secondaryOutcomes measure: Nausea and Vomiting, eligibilityModule sex: ALL, minimumAge: 60 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Erciyes University, city: Kayseri̇, state: Talas, zip: 38000, country: Turkey, geoPoint lat: 38.73222, lon: 35.48528, hasResults: False
protocolSection identificationModule nctId: NCT06316635, orgStudyIdInfo id: 2023/209, secondaryIdInfos id: self-funding, type: OTHER, domain: Erciyes University, briefTitle: Microplastics in Otitis Media With Effusion Material, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-20, primaryCompletionDateStruct date: 2024-04-20, completionDateStruct date: 2024-04-20, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Kerem Kökoğlu, class: OTHER, descriptionModule briefSummary: Microplastic rate is increasing ib athmosphere. They can be found in lung, kidney, heart, even placenta. Otitis media with effusion (OME) is a clinical condition that is ver common in children. Biofilms are blamed in the pathogenesis of OME. Microplastics can include biofilms. Importance of microplastics for potential pathogens and their toxicity aspects should be enlighted with studies. This study aims to investigate presency of microplastics in middle ear fluid of patients with OME., conditionsModule conditions: Microplastics, conditions: Otitis Media With Effusion, conditions: Biofilms, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: ventilation tube insertion, outcomesModule primaryOutcomes measure: Microplastic presence, eligibilityModule sex: ALL, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Erciyes University Medical School, status: RECRUITING, city: Kayseri, zip: 38039, country: Turkey, contacts name: KEREM KÖKOĞLU, role: CONTACT, phone: 535-205-6780, email: dr.kokoglu@gmail.com, contacts name: Onat B Taş, M.D., role: CONTACT, phone: 90 505-702-2227, email: onat-berkay@hotmail.com, contacts name: Mehmet I Şahin, Assoc. Prof, M.D., role: SUB_INVESTIGATOR, geoPoint lat: 38.73222, lon: 35.48528, hasResults: False