hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06297213, orgStudyIdInfo id: R-2487-SS-01, briefTitle: R-2487 in Patients With Sjogren's Syndrome (SS), acronym: R-2487-SS-01, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2026-08-30, completionDateStruct date: 2026-08-30, studyFirstPostDateStruct date: 2024-03-07, lastUpdatePostDateStruct date: 2024-04-12, sponsorCollaboratorsModule leadSponsor name: Rise Therapeutics LLC, class: INDUSTRY, descriptionModule briefSummary: The goal of this study is to determine the safety and tolerability of orally taken probiotic (R-2487) in patients with Sjogren's Syndrome.Patients will take an oral dosage of probiotic (R-2487) and physicians will assess and measure their Sjogren's Syndrome. Blood and fecal evaluations of inflammation and assessment of probiotic (R-2487) on fecal level will also be measured., conditionsModule conditions: Sjogren's Syndrome, conditions: Sjögren, conditions: Sjögren Syndrome, Unspecified, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 36, type: ESTIMATED, armsInterventionsModule interventions name: R-2487, outcomesModule primaryOutcomes measure: Incidence and severity of adverse events and their relationship to R-2487 (probiotic) administration, secondaryOutcomes measure: Change in disease activity through Clinical European League Against Rheumatism Sjögren's Syndrome Disease Activity Index (ClinESSDAI), secondaryOutcomes measure: Change in Patient reported general health questionnaire Short Form Health Survey-36(SF-36), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06297200, orgStudyIdInfo id: 24-050, briefTitle: Low-Intensity Focused Ultrasound and the Complex Patient, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-10, completionDateStruct date: 2025-10, studyFirstPostDateStruct date: 2024-03-07, lastUpdatePostDateStruct date: 2024-03-07, sponsorCollaboratorsModule leadSponsor name: Virginia Polytechnic Institute and State University, class: OTHER, collaborators name: Salem VA Medical Center, collaborators name: Washington DC VA Medical Center, descriptionModule briefSummary: Studying the effects of Low Intensity Focused Ultrasound (LIFU) on measures of pain, craving, and anxiety in a complex patient population., conditionsModule conditions: Opioid Use Disorder, conditions: Chronic Pain, conditions: Anxiety Disorder, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, maskingDescription: Sham trials will be utilized within subject. All subjects will receive sham and ultrasound conditions., enrollmentInfo count: 25, type: ESTIMATED, armsInterventionsModule interventions name: Low-Intensity Focused Ultrasound, interventions name: Low-Intensity Focused Ultrasound - sham, outcomesModule primaryOutcomes measure: Incidence of Treatment-Emergent Adverse Events via a neurological examination, primaryOutcomes measure: Incidence of Treatment-Emergent Adverse Events via a side effects questionnaire, primaryOutcomes measure: Changes in Heart Rate (HR), primaryOutcomes measure: Changes in Respiration Rate (RR), primaryOutcomes measure: Changes in mood via visual analog mood scale (VAMS), primaryOutcomes measure: Changes in Blood Pressure (BP), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Fralin Biomedical Research Institute at VTC, city: Roanoke, state: Virginia, zip: 24016, country: United States, contacts name: Jessica Florig, MPH, role: CONTACT, phone: 540-526-2261, email: jnw@vtc.vt.edu, contacts name: Wynn Legon, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 37.27097, lon: -79.94143, hasResults: False
protocolSection identificationModule nctId: NCT06297187, orgStudyIdInfo id: C-CUSAWH-001, briefTitle: Cavitronic Ultrasonic Surgical Aspiration (CUSA) Women's Health Study, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-02-23, primaryCompletionDateStruct date: 2024-07, completionDateStruct date: 2024-08, studyFirstPostDateStruct date: 2024-03-07, lastUpdatePostDateStruct date: 2024-03-07, sponsorCollaboratorsModule leadSponsor name: Integra LifeSciences Corporation, class: INDUSTRY, descriptionModule briefSummary: The study is a single arm, retrospective, single-center, post market registry.The purpose of this Registry is to collect data to demonstrate the safety and performance of CUSA® for the treatment of Vulvar Intraepithelial Neoplasia (VIN) and condyloma acuminata., conditionsModule conditions: Vulvar Intraepithelial Neoplasia, conditions: Condylomata Acuminata, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 75, type: ESTIMATED, armsInterventionsModule interventions name: CUSA (Cavitronic Ultrasonic Surgical Aspirator), outcomesModule primaryOutcomes measure: Proportion of Subjects with Complete Removal of Vulvar Intraepithelial Neoplasia and condyloma acuminata, secondaryOutcomes measure: Primary Site Recurrence, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The Center for Cancer and Blood Disorders, city: Dallas, state: Texas, zip: 76014, country: United States, geoPoint lat: 32.78306, lon: -96.80667, hasResults: False
protocolSection identificationModule nctId: NCT06297174, orgStudyIdInfo id: BE23-035, briefTitle: Bioequivalence Study of Generic Racecadotril 100 mg Capsules Under Fasting Conditions, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-08-26, primaryCompletionDateStruct date: 2024-09-17, completionDateStruct date: 2024-09-20, studyFirstPostDateStruct date: 2024-03-07, lastUpdatePostDateStruct date: 2024-03-07, sponsorCollaboratorsModule leadSponsor name: Pharma Nueva, class: INDUSTRY, descriptionModule briefSummary: Objectives:To determine and compare the rate and extent of absorption of a test formulation with that of a reference innovator formulation when given as equal labeled dose in healthy subjects under fasting conditionsStudy Design:An open label, randomized, two-treatment, four-period, two-sequence, replicate crossover bioequivalence study in healthy Thai volunteers under fasting conditions with at least 7 days washout period between the administrations of investigational products of each period, conditionsModule conditions: Healthy Vollunteer, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: NONE, enrollmentInfo count: 44, type: ESTIMATED, armsInterventionsModule interventions name: Racecadotril 100 mg Capsules, interventions name: HIDRASEC®, outcomesModule primaryOutcomes measure: Plasma area Under the Curve (AUC(0-36hr)) for Racecadotril, primaryOutcomes measure: Peak Plasma Concentration (Cmax) of Racecadotril, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06297161, orgStudyIdInfo id: B1871065, briefTitle: A Study to Learn About the Study Medicine Bosulif in Adult Patients With Chronic Myeloid Leukemia(CML)., statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2029-12-31, completionDateStruct date: 2029-12-31, studyFirstPostDateStruct date: 2024-03-07, lastUpdatePostDateStruct date: 2024-03-07, sponsorCollaboratorsModule leadSponsor name: Pfizer, class: INDUSTRY, descriptionModule briefSummary: The purpose of this study is to look at how safe and effective is bosulif in routine clinical practice.This study is seeking for participants who are:* Adult Patients who are just confirmed to have Chronic Myeloid Leukemia (CML) defined in Local Product Document (LPD). CML is a type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood. LPD explains what a medicine's benefits and problems are. LPD also explains how to use the medicine correctly in Korea.* willing to take part in the study after being informed about the study. All participants in this study will receive bosulif. All participants who have entered this study should meet the usual prescribing criteria for bosulif as per the LPD. The participants will be treated with bosulif under routine clinical practice in Korea.The study will look at the experiences of people receiving the study medicine. This will help to see if the study medicine is safe and effective.In this study all treatment and checking of the patients will be done as per the study doctor. The study can be performed in Korean health care centers where bosulif is prescribed to treat CML after the patients have agreed to take part in the study., conditionsModule conditions: Chronic Leukemia Myelogenous, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 600, type: ESTIMATED, armsInterventionsModule interventions name: Bosulif, outcomesModule primaryOutcomes measure: Incidence of AEs, secondaryOutcomes measure: Hematologic response: CHR, not achieved, secondaryOutcomes measure: Cytogenetic response: CCyR, PCyR, mCyR, not achieved, secondaryOutcomes measure: Molecular response: EMR, MMR, MR4.0, MR4.5, not achieved, secondaryOutcomes measure: Relapse after Bosulif response, eligibilityModule sex: ALL, minimumAge: 20 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06297135, orgStudyIdInfo id: HSR-2023-020, briefTitle: A Feasibility Study of a Support Program for Building New Parent-child Behavioral Habits, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-01, primaryCompletionDateStruct date: 2025-03-31, completionDateStruct date: 2025-03-31, studyFirstPostDateStruct date: 2024-03-07, lastUpdatePostDateStruct date: 2024-03-07, sponsorCollaboratorsModule leadSponsor name: Okinawa Institute of Science and Technology Graduate University, class: OTHER, collaborators name: Miyazaki International College, collaborators name: Japan society for the promotion of science, descriptionModule briefSummary: This study evaluates the feasibility and preliminary impacts of a new parent support program consisting of a series of educational videos, delivered via a popular texting platform. For this pilot project, the program content is focused on teaching parents strategies to better manage one of the commonly reported challenges children face, a transition to a non-preferred activity. Parents with children demonstrating inattentive, hyperactive and impulsive behavior and experiencing difficulties with daily transition routines are invited to participate in the study., conditionsModule conditions: ADHD, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Behavioral Parent Training, outcomesModule primaryOutcomes measure: Number of videos viewed, primaryOutcomes measure: Percentage of completed daily ratings, primaryOutcomes measure: Participant satisfaction, secondaryOutcomes measure: Parent-rated child's difficulties with daily transitions, secondaryOutcomes measure: Parent-rated child's impairment related to transition difficulties, secondaryOutcomes measure: Positive parenting, secondaryOutcomes measure: Negative parenting, secondaryOutcomes measure: Parenting stress, otherOutcomes measure: ADHD symptoms, otherOutcomes measure: ODD symptoms, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Okinawa Institute of Science and Technology Graduate University, status: RECRUITING, city: Onna, state: Okinawa, zip: 904-0495, country: Japan, contacts name: Emi Furukawa, PhD, role: CONTACT, phone: +81989668814, email: adhd@oist.jp, contacts name: Emi Furukawa, PhD, role: PRINCIPAL_INVESTIGATOR, locations facility: Miyazaki International College, status: RECRUITING, city: Miyazaki, zip: 889-1605, country: Japan, contacts name: Aya Kasai, PhD, role: CONTACT, phone: +81985855931, email: akasai@sky.miyazaki-mic.ac.jp, contacts name: Aya Kasai, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 31.91667, lon: 131.41667, hasResults: False
protocolSection identificationModule nctId: NCT06297044, orgStudyIdInfo id: 2017.20, briefTitle: Neural and Cognitive Correlates of Pragmatic Abilities, acronym: APACS_Neuro, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2018-03-29, primaryCompletionDateStruct date: 2025-12-31, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: IRCCS San Camillo, Venezia, Italy, class: OTHER, descriptionModule briefSummary: Pragmatics of language refers to the set of abilities that allow one to use and interpret language according to context and, in general, to communicate effectively. Disorders in the pragmatics of language are prevalent in various clinical populations. They are a cause of social withdrawal and worse quality of life, both for patients directly affected and for their family members. Despite this, this type of disorder is rarely considered in neuropsychological assessment and rehabilitation.This study's objective is to characterize pragmatic deficits in various neurological populations, allowing for the most accurate diagnosis possible and leading to the planning of personalized and effective Rehabilitation Plans., conditionsModule conditions: Right Hemispheric Stroke, conditions: Left Hemispheric Stroke, conditions: Traumatic Brain Injury, conditions: Right Hemispheric Brain Tumor, conditions: Left Hemispheric Brain Tumor, conditions: Mild Cognitive Impairment, conditions: Healthy, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 324, type: ESTIMATED, armsInterventionsModule interventions name: Neuropsychological assessment, outcomesModule primaryOutcomes measure: Pragmatic Profile, secondaryOutcomes measure: Theory of Mind, secondaryOutcomes measure: Functional Communication Abilities, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: San Camillo IRCCS s.r.l., city: Venice-Lido, state: Venice, zip: 30126, country: Italy, geoPoint lat: 45.4131, lon: 12.3742, hasResults: False
protocolSection identificationModule nctId: NCT06297031, orgStudyIdInfo id: 2020/20, briefTitle: Heat Application to the Sacral Region and Pain Level During the First Stage of Labor, statusModule overallStatus: COMPLETED, startDateStruct date: 2020-04-01, primaryCompletionDateStruct date: 2021-05-01, completionDateStruct date: 2021-05-30, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Istanbul Demiroglu Bilim University, class: OTHER, descriptionModule briefSummary: The aim of this study was to determine the effect of hot application applied to the sacral region during first stage of labor on women's pain level and labor process., conditionsModule conditions: Heat Exposure, conditions: Labor Pain, conditions: Apgar Score, conditions: Duration of Labor, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 134, type: ACTUAL, armsInterventionsModule interventions name: heat application, outcomesModule primaryOutcomes measure: Change From Baseline labor Pain at three times, secondaryOutcomes measure: Duration of the first stage of labor, secondaryOutcomes measure: Change From Baseline APGAR score after delivery, secondaryOutcomes measure: Change From Baseline Fetal Heart Rate, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Demiroglu Bilim University, city: Istanbul, zip: 34384, country: Turkey, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06297018, orgStudyIdInfo id: February 18, 2024, briefTitle: Bioenergy, Depression, Anxiety and Stress After Liver Transplantation, statusModule overallStatus: TERMINATED, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2024-02-02, completionDateStruct date: 2024-02-09, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Istanbul Aydın University, class: OTHER, descriptionModule briefSummary: In this study, the investigators aimed to examine the effect of bioenergy application on depression, anxiety and stress after liver transplantation., conditionsModule conditions: Mental Health Issue, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: Interventional Crossover Assignment, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: QUADRUPLE, maskingDescription: Experimental, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 140, type: ACTUAL, armsInterventionsModule interventions name: Bioenergy application, outcomesModule primaryOutcomes measure: Anxiety, stress, depression: Measurement will be made with the Depression Anxiety Stress 21 Scale (DASS-21: Score range 21-63), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Semra Bulbuloglu, city: Istanbul, country: Turkey, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06296992, orgStudyIdInfo id: B2023:035, briefTitle: Type 1 Diabetes, Exercise and Mentoring Trial, acronym: TEAM, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2027-04, completionDateStruct date: 2027-05, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: University of Manitoba, class: OTHER, collaborators name: Juvenile Diabetes Research Foundation, collaborators name: Canadian Institutes of Health Research (CIHR), descriptionModule briefSummary: The proposed study aims to improve the psychosocial health of adolescents living with type 1 diabetes (T1D). The study will generate knowledge and support knowledge mobilization about the effectiveness of a novel model of care for psychosocial health and self-management for adolescents living with type 1 diabetes (T1D). The novel model of care is the recruitment and training if young adult mentors to deliver a behavioural intervention that empowers adolescents with T1D to increase daily physical activity. The study will also advance the development and implementation of this peer mentoring model to improve the psychosocial health of adolescents with T1D., conditionsModule conditions: Type 1 Diabetes, conditions: Physical Activity, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: DOUBLE, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: 12-week TEAM peer mentor program, outcomesModule primaryOutcomes measure: Enrollment rates, primaryOutcomes measure: Adherence to the intervention arms, primaryOutcomes measure: Retention for follow-up measurements, secondaryOutcomes measure: Physical activity, secondaryOutcomes measure: Quality of Life (DQOL), secondaryOutcomes measure: Quality of Life (PedsQL 4.0), otherOutcomes measure: Diabetes Distress, otherOutcomes measure: Mastery, otherOutcomes measure: Autonomy, otherOutcomes measure: Motivation for physical activity (LCE), otherOutcomes measure: Readiness for change, otherOutcomes measure: Motivation to engage in exercise, otherOutcomes measure: Motivation for Physical Activity (EMI-2), eligibilityModule sex: ALL, minimumAge: 13 Years, maximumAge: 17 Years, stdAges: CHILD, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06296979, orgStudyIdInfo id: 0881-N-23, briefTitle: Effectiveness of Noninvasive Phrenic Nerve Neuromodulation in Shoulder Pain and Hepatobiliary Visceral Comorbidity., statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-20, primaryCompletionDateStruct date: 2026-12-01, completionDateStruct date: 2026-12-01, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-04-15, sponsorCollaboratorsModule leadSponsor name: University of Seville, class: OTHER, descriptionModule briefSummary: Pain, particularly shoulder pain, is a social and economic problem worldwide. Although visceral pathology is not yet taken into account in the diagnosis of these pains, it is likely that on numerous occasions the hepatobiliary visceral condition causes referred pain in the metameric area belonging to the shoulder due to the involvement of the phrenic nerve. Therefore, the aim of this project is to study the response of treatment by neuromodulation of the phrenic nerve for shoulder pain in patients with associated hepatobiliary pathologies, assessing the possible visceral involvement in the symptomatology., conditionsModule conditions: Shoulder Pain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 34, type: ESTIMATED, armsInterventionsModule interventions name: Phrenic nerve neuromodulation, interventions name: common Physical therapy, outcomesModule primaryOutcomes measure: Numeric Pain Rating Scale, secondaryOutcomes measure: Algometry, secondaryOutcomes measure: Goniometry passive, secondaryOutcomes measure: Quick Dash questionnaire, secondaryOutcomes measure: Goniometriy active, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 64 Years, stdAges: ADULT, contactsLocationsModule locations facility: Centro de Salud Ronda Histórica, status: RECRUITING, city: Sevilla, zip: 41008, country: Spain, contacts name: Deseada López Carballo, Dra, role: CONTACT, email: deseada.lopez.sspa@juntadeandalucia.es, geoPoint lat: 37.38283, lon: -5.97317, locations facility: Centro de Salud las Letanías, status: RECRUITING, city: Sevilla, zip: 41013, country: Spain, contacts name: Alicia Valero Sáinz, role: CONTACT, phone: 649532242, phoneExt: +34, email: aliciavalerio@hotmail.com, geoPoint lat: 37.38283, lon: -5.97317, locations facility: Centro de Salud Bellavista, status: RECRUITING, city: Sevilla, zip: 41014, country: Spain, contacts name: María Isabel Morilla Párraga, role: CONTACT, phone: 609582376, phoneExt: +34, email: fisioaljarafe@gmail.com, geoPoint lat: 37.38283, lon: -5.97317, hasResults: False