protocolSection identificationModule nctId: NCT06320379, orgStudyIdInfo id: RB071522, briefTitle: Zypan Functional Dyspepsia, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-03-15, primaryCompletionDateStruct date: 2024-06-01, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: National University of Natural Medicine, class: OTHER, descriptionModule briefSummary: The purpose of this study is to determine the effects of a readily available dietary supplement on quality of life and digestion in adults with functional dyspepsia., conditionsModule conditions: Dyspepsia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Participants will be randomized to take either a placebo or Zypan dietary supplement three times per day for four weeks., primaryPurpose: OTHER, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 64, type: ESTIMATED, armsInterventionsModule interventions name: Zypan, interventions name: Placebo Comparator, outcomesModule primaryOutcomes measure: Protein Assimilation, primaryOutcomes measure: Protein Assimilation, secondaryOutcomes measure: Mineral concentrations in blood, secondaryOutcomes measure: Mineral concentrations in blood, secondaryOutcomes measure: Fat-soluble vitamin concentration in blood, secondaryOutcomes measure: Fat-soluble vitamins, secondaryOutcomes measure: Leeds Dyspepsia Questionnaire, secondaryOutcomes measure: Leeds Dyspepsia Questionnaire, secondaryOutcomes measure: Patient Reported Outcomes Measurement Information System (PROMIS)-29 Physical Function Subscale, secondaryOutcomes measure: Patient Reported Outcomes Measurement Information System (PROMIS)-29 Physical Function Subscale, otherOutcomes measure: Microbiota Relative Abundance and Composition, otherOutcomes measure: Microbiota Relative Abundance and Composition, otherOutcomes measure: Blood glucose, otherOutcomes measure: Blood glucose, otherOutcomes measure: Urea Nitrogen, otherOutcomes measure: Urea Nitrogen, otherOutcomes measure: Creatinine, otherOutcomes measure: Creatinine, otherOutcomes measure: Urea Nitrogen to creatinine ratio, otherOutcomes measure: Urea Nitrogen to creatinine ratio, otherOutcomes measure: Sodium, otherOutcomes measure: Sodium, otherOutcomes measure: Potassium, otherOutcomes measure: Potassium, otherOutcomes measure: Chloride, otherOutcomes measure: Chloride, otherOutcomes measure: Carbon Dioxide, otherOutcomes measure: Carbon Dioxide, otherOutcomes measure: Calcium, otherOutcomes measure: Calcium, otherOutcomes measure: Total Protein, otherOutcomes measure: Total Protein, otherOutcomes measure: Albumin, otherOutcomes measure: Albumin, otherOutcomes measure: Globulin, otherOutcomes measure: Globulin, otherOutcomes measure: Albumin to Globulin ratio, otherOutcomes measure: Albumin to Globulin ratio, otherOutcomes measure: Bilirubin, otherOutcomes measure: Bilirubin, otherOutcomes measure: Alkaline Phosphatase, otherOutcomes measure: Alkaline Phosphatase, otherOutcomes measure: aspartate aminotransferase, otherOutcomes measure: aspartate aminotransferase, otherOutcomes measure: Alanine aminotransferase, otherOutcomes measure: Alanine aminotransferase, otherOutcomes measure: Estimated glomerular filtration rate, otherOutcomes measure: Estimated glomerular filtration rate, otherOutcomes measure: White blood cell count, otherOutcomes measure: White blood cell count, otherOutcomes measure: Red blood cell count, otherOutcomes measure: Red blood cell count, otherOutcomes measure: Hemoglobin, otherOutcomes measure: Hemoglobin, otherOutcomes measure: Hematocrit, otherOutcomes measure: Hematocrit, otherOutcomes measure: Mean corpuscular volume, otherOutcomes measure: Mean corpuscular volume, otherOutcomes measure: Mean corpuscular hemoglobin, otherOutcomes measure: Mean corpuscular hemoglobin, otherOutcomes measure: Mean corpuscular hemoglobin concentration, otherOutcomes measure: Mean corpuscular hemoglobin concentration, otherOutcomes measure: Erythrocyte distribution width, otherOutcomes measure: Erythrocyte distribution width, otherOutcomes measure: Platelet count, otherOutcomes measure: Platelet count, otherOutcomes measure: Neutrophils, otherOutcomes measure: Neutrophils, otherOutcomes measure: Band Neutrophils, otherOutcomes measure: Band Neutrophils, otherOutcomes measure: Absolute band neutrophils, otherOutcomes measure: Absolute band neutrophils, otherOutcomes measure: Metamyelocytes, otherOutcomes measure: Metamyelocytes, otherOutcomes measure: Absolute Metamyelocytes, otherOutcomes measure: Absolute Metamyelocytes, otherOutcomes measure: Myelocytes, otherOutcomes measure: Myelocytes, otherOutcomes measure: Absolute Myelocytes, otherOutcomes measure: Absolute Myelocytes, otherOutcomes measure: Promyelocytes, otherOutcomes measure: Promyelocytes, otherOutcomes measure: Absolute Promyelocytes, otherOutcomes measure: Absolute Promyelocytes, otherOutcomes measure: Absolute Neutrophils, otherOutcomes measure: Absolute Neutrophils, otherOutcomes measure: Lymphocytes, otherOutcomes measure: Lymphocytes, otherOutcomes measure: Reactive Lymphocytes, otherOutcomes measure: Reactive Lymphocytes, otherOutcomes measure: Absolute Lymphocytes, otherOutcomes measure: Absolute Lymphocytes, otherOutcomes measure: Monocytes, otherOutcomes measure: Monocytes, otherOutcomes measure: Absolute monocytes, otherOutcomes measure: Absolute monocytes, otherOutcomes measure: Eosinophils, otherOutcomes measure: Eosinophils, otherOutcomes measure: Absolute Eosinophils, otherOutcomes measure: Absolute Eosinophils, otherOutcomes measure: Basophils, otherOutcomes measure: Basophils, otherOutcomes measure: Absolute Basophils, otherOutcomes measure: Absolute Basophils, otherOutcomes measure: Blasts, otherOutcomes measure: Blasts, otherOutcomes measure: Absolute Blasts, otherOutcomes measure: Absolute Blasts, otherOutcomes measure: Nucleated red blood cells, otherOutcomes measure: Absolute Nucleated red blood cells, otherOutcomes measure: Absolute Nucleated red blood cells, otherOutcomes measure: Platelet mean volume, otherOutcomes measure: Platelet mean volume, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Helfgott Research Institute, status: RECRUITING, city: Portland, state: Oregon, zip: 97201, country: United States, contacts name: Anders Gundersen, MS, role: CONTACT, geoPoint lat: 45.52345, lon: -122.67621, hasResults: False