protocolSection identificationModule nctId: NCT06309511, orgStudyIdInfo id: 09C218, briefTitle: Subendocardial Viability Ratio in Hypertension, acronym: SEVR-HT, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-10-01, primaryCompletionDateStruct date: 2026-12-31, completionDateStruct date: 2026-12-31, studyFirstPostDateStruct date: 2024-03-13, lastUpdatePostDateStruct date: 2024-03-13, sponsorCollaboratorsModule leadSponsor name: Istituto Auxologico Italiano, class: OTHER, descriptionModule briefSummary: The aim of the research is to evaluate the Subendocardial Viability Ratio (SEVR) in hypertensive patients, using non-invasive arterial tonometry, and to establish the influencing factors and the possibility of predicting cardiovascular morbidity and mortality in arterial hypertension.The SEVR will be evaluated on all patients belonging to the Arterial Hypertension Centers undergoing non-invasive arterial tonometry.The SEVR is calculated on the morphology of the central pressure wave as the ratio between the DPTI (diastolic pressure-time index), i.e. the area between the carotid pressure curve and the ventricular pressure curve during the diastolic phase, and the SPTI ( systolic pressure-time index), i.e. the area under the carotid pressure curve during the systolic phase.The SEVR will be correlated with the anthropometric and pathology variables which will be collected in an appropriate database., conditionsModule conditions: Hypertension, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 3000, type: ESTIMATED, armsInterventionsModule interventions name: Arterial tonometry, outcomesModule primaryOutcomes measure: Buckberg index, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Centro di Prevenzione e Cura dell'Ipertensione Arteriosa "Alessandro Filippi", status: RECRUITING, city: Mascalucia, state: Catania, country: Italy, contacts name: Antonino Di Guardo, MD, role: CONTACT, email: ninodiguardo58@gmail.com, contacts name: Massimo Catanuso, MD, role: CONTACT, email: catanusomassimo@hotmail.it, geoPoint lat: 37.57465, lon: 15.04964, locations facility: Unità Operativa Semplice Dipartimentale Ipertensione Arteriosa "Anna Maria Pirrelli", Università degli Studi di Bari "Aldo Moro". Policlinico Consorziale di Bari, status: RECRUITING, city: Bari, country: Italy, contacts name: Pietro Nazzaro, MD, role: CONTACT, email: pietro.nazzaro@uniba.it, contacts name: Sebastiano Cicco, MD, role: CONTACT, email: sebastiano.cicco@uniba.it, geoPoint lat: 41.11148, lon: 16.8554, locations facility: Istituto Auxologico Italiano IRCCS, status: RECRUITING, city: Milano, zip: 20145, country: Italy, contacts name: Paolo Salvi, MD, role: CONTACT, phone: +390261911, phoneExt: 2968, email: p.salvi@auxologico.it, geoPoint lat: 45.46427, lon: 9.18951, locations facility: Medicina II Cardiovascolare, AUSL-IRCCS di Reggio Emilia, status: RECRUITING, city: Reggio Emilia, country: Italy, contacts name: Angelo Ghirarduzzi, MD, role: CONTACT, email: ghirarduzzi.angelo@ausl.re.it, contacts name: Chiara Grasselli, MD, role: CONTACT, email: chiara.grasselli@ausl.re.it, geoPoint lat: 44.69825, lon: 10.63125, locations facility: Dipartimento di Scienze Mediche, Chirurgiche e della Salute, Università degli studi di Trieste, status: RECRUITING, city: Trieste, country: Italy, contacts name: Andrea Grillo, MD, role: CONTACT, email: andr.grillo@gmail.com, contacts name: Bruno Fabris, MD, role: CONTACT, email: b.fabris@fmc.units.it, geoPoint lat: 45.64953, lon: 13.77679, hasResults: False