protocolSection identificationModule nctId: NCT06322862, orgStudyIdInfo id: H-23042430, briefTitle: Intraoperative Intestinal Perfusion Assessment by Fluorescence Angiography in Emergency Surgery, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-05, primaryCompletionDateStruct date: 2026-12-01, completionDateStruct date: 2027-02-01, studyFirstPostDateStruct date: 2024-03-21, lastUpdatePostDateStruct date: 2024-03-21, sponsorCollaboratorsModule leadSponsor name: Rigshospitalet, Denmark, class: OTHER, descriptionModule briefSummary: This is a prospective, multicentre, non-randomized cohort study using real-time intraoperative visualization of bowel perfusion by indocyanine green (ICG) in all-cause bowel ischemia.At intraoperative finding of bowel ischemia, the initial intraoperative plan is noted and resection margins marked with a steril pen. A fluorescence angiography will be performed and the surgeon will note whether the suspected ischemic bowel is perfused, whether there is a change in the resection margins in centimeters, and if the intraoperative plan has changed. If resection is indicated and the strategy of choice is an anastomosis, a renewed fluorescence angiography will be performed to assess anastomotic perfusion., conditionsModule conditions: Bowel; Ischemic, Acute, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Indocyanine green, outcomesModule primaryOutcomes measure: Change of strategy, secondaryOutcomes measure: Anastomosis, secondaryOutcomes measure: Quantification using q-ICG, secondaryOutcomes measure: Stomas, secondaryOutcomes measure: Second-look, secondaryOutcomes measure: Anastomotic leaks, secondaryOutcomes measure: Postoperative medical complications, secondaryOutcomes measure: Postoperative surgical complications, secondaryOutcomes measure: Mortality, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Department of Organ Surgery and Transplantation, status: RECRUITING, city: Copenhagen, state: Hovedstaden, zip: 2100, country: Denmark, contacts name: Sermed Ellebæk Nicolae, MD, role: CONTACT, phone: +4535459666, email: sermed.ellebaek.nicolae@regionh.dk, contacts name: Michael P Achiam, MD, DMSc, role: CONTACT, phone: +45 3545 0441, email: michael.patrick.achiam.01@regionh.dk, geoPoint lat: 55.67594, lon: 12.56553, locations facility: Department of Surgery, Bispebjerg Hospital, status: NOT_YET_RECRUITING, city: Bispebjerg, country: Denmark, contacts name: Peter Bonde, MD, role: CONTACT, geoPoint lat: 55.71017, lon: 12.53147, locations facility: Department of Surgery, Herlev Hospital, status: NOT_YET_RECRUITING, city: Herlev, country: Denmark, contacts name: Jakob Burcharth, MD, PhD, role: CONTACT, geoPoint lat: 55.72366, lon: 12.43998, locations facility: Department of Surgery, Nordsjællands Hospital, status: NOT_YET_RECRUITING, city: Hillerød, country: Denmark, contacts name: Mai-Britt Tolstrup, MD, PhD, role: CONTACT, geoPoint lat: 55.92791, lon: 12.30081, locations facility: Department of Surgery, Hvidovre Hospital, status: NOT_YET_RECRUITING, city: Hvidovre, country: Denmark, contacts name: Morten Laksafoss Lauritsen, MD, role: CONTACT, geoPoint lat: 55.65719, lon: 12.47364, hasResults: False