protocolSection identificationModule nctId: NCT06290193, orgStudyIdInfo id: 23-392, briefTitle: Study of Acute Normovolemic Hemodilution (ANH) in People With Ovarian Cancer Who Are Having Primary Cytoreductive Surgery, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-23, primaryCompletionDateStruct date: 2029-02-23, completionDateStruct date: 2029-02-23, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Memorial Sloan Kettering Cancer Center, class: OTHER, descriptionModule briefSummary: Participants will be scheduled for primary cytoreductive surgery as part of their standard care. Before surgery, participants will be assigned by chance to a study group. Depending on which group they are in, they will receive either acute normovolemic hemodilution/ANH during surgery or standard surgical management during surgery. The researchers think acute normovolemic hemodilution/ANH may decrease the need for allogenic blood transfusion/ABT in people having primary cytoreductive surgery., conditionsModule conditions: Ovarian Cancer, conditions: Fallopian Tube Carcinoma, conditions: Ovarian Carcinoma, conditions: Peritoneal Carcinoma, conditions: Ovarian Cancer Stage IIIC, conditions: Fallopian Tube Cancer Stage IIIC, conditions: Ovarian Cancer Stage IV, conditions: Fallopian Tube Cancer Stage IV, conditions: Fallopian Tube Cancer, conditions: Peritoneal Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 86, type: ESTIMATED, armsInterventionsModule interventions name: Acute Normovolemic Hemodilution/ANH, outcomesModule primaryOutcomes measure: Comparison of the rate of allogenic red blood cell transfusions between the Acute Normovolemic Hemodilution (ANH) and standard of care arm, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Memoral Sloan Kettering at Basking Ridge (Limited Protocol Activities), status: RECRUITING, city: Basking Ridge, state: New Jersey, zip: 07920, country: United States, contacts name: Dennis Chi, MD, role: CONTACT, phone: 212-639-5016, geoPoint lat: 40.70621, lon: -74.54932, locations facility: Memorial Sloan Kettering Monmouth (Limited protocol activities), status: RECRUITING, city: Middletown, state: New Jersey, zip: 07748, country: United States, contacts name: Dennis Chi, MD, role: CONTACT, phone: 212-639-5016, geoPoint lat: 40.39652, lon: -74.09211, locations facility: Memorial Sloan Kettering Bergen (Limited protocol activities), status: RECRUITING, city: Montvale, state: New Jersey, zip: 07645, country: United States, contacts name: Dennis Chi, MD, role: CONTACT, phone: 212-639-5016, geoPoint lat: 41.04676, lon: -74.02292, locations facility: Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Limited protocol activities), status: RECRUITING, city: Commack, state: New York, zip: 11725, country: United States, contacts name: Dennis Chi, MD, role: CONTACT, phone: 212-639-5016, geoPoint lat: 40.84288, lon: -73.29289, locations facility: Memorial Sloan Kettering Westchester (Limited protocol activities), status: RECRUITING, city: Harrison, state: New York, zip: 10604, country: United States, contacts name: Dennis Chi, MD, role: CONTACT, phone: 212-639-5016, geoPoint lat: 40.96899, lon: -73.71263, locations facility: Memorial Sloan Kettering Cancer Center (All protocol activities), status: RECRUITING, city: New York, state: New York, zip: 10065, country: United States, contacts name: Dennis Chi, MD, role: CONTACT, phone: 212-639-5016, geoPoint lat: 40.71427, lon: -74.00597, locations facility: Memorial Sloan Kettering Nassau (Limited Protocol Activities), status: RECRUITING, city: Uniondale, state: New York, zip: 11553, country: United States, contacts name: Dennis Chi, MD, role: CONTACT, phone: 212-639-5016, geoPoint lat: 40.70038, lon: -73.59291, hasResults: False