protocolSection identificationModule nctId: NCT06300619, orgStudyIdInfo id: 2022-066, briefTitle: Pilates+4MS: Pilates Intervention for Multiple Sclerosis, acronym: P+4MS, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-04-05, primaryCompletionDateStruct date: 2022-08-25, completionDateStruct date: 2022-08-25, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: University of Colorado, Colorado Springs, class: OTHER, collaborators name: University of Illinois at Urbana-Champaign, descriptionModule briefSummary: The goal of this clinical trial is to test the physical health benefits of seated Pilates in the multiple sclerosis (MS) population. The main questions it aims to answer are: 1) is it feasible to deliver a seated Pilates class for 12 weeks, twice weekly over Zoom in a group format among participants with mild, moderate, and severe multiple sclerosis? 2) what are the mobility, balance, and symptom benefits of a 12-week seated Pilates class? 3) Does incorporating hip and shoulder stabilization augment the benefits compared to a standard seated Pilates protocol? 4) Are there benefits to physical activity participation? Participants will be screened over the phone for eligibility criteria and then scheduled for in-person data collection. In person data collection will involve: 1) completing the Timed 25-Foot Walk a total of 4 times, 2) the Timed Up and Go a total of 4 times, 3) the Berg Balance Scale a total of 2 times, and 4) a set of 8 questionnaires about multiple sclerosis symptoms and impact, and physical activity behavior. Participants will receive a FitBit and then will be randomized into the Pilates only group or the Pilates+4-Quadrant stability group for the intervention. The intervention is 12 weeks long, both groups meet twice weekly on Zoom for 60 minutes with 1 of 2 instructors and other class participants (12 per group). They wear the FitBit for all 12 weeks and then return for testing to repeat testing items 1-4 above. Researchers will compare the functional outcomes between the Pilates only group and the Pilates+4-Quadrant Stability group to see if there are differences in mobility, balance and physical activity outcomes., conditionsModule conditions: Multiple Sclerosis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: SINGLE, maskingDescription: Participants know that there are 2 Pilates groups, but not which group is under investigation vs. the comparison group., whoMasked: PARTICIPANT, enrollmentInfo count: 22, type: ACTUAL, armsInterventionsModule interventions name: Pilates+4, interventions name: Pilates, outcomesModule primaryOutcomes measure: Timed 25 Foot Walk, primaryOutcomes measure: Timed Up and Go, primaryOutcomes measure: Berg Balance Scale, secondaryOutcomes measure: Triaxial Accelerometer (FitBit) Physical Activity Data (minutes of wear time in sedentary time and light, moderate and vigorous physical activity), secondaryOutcomes measure: The Godin-Shepherd Leisure Time Exercise Questionnaire, secondaryOutcomes measure: Late-Life Function and Disability Instrument Short Form, secondaryOutcomes measure: Leeds Multiple Sclerosis Quality of Life Scale, secondaryOutcomes measure: Modified Fatigue Impact Scale, secondaryOutcomes measure: Multiple Sclerosis Impact Scale, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hybl Sports Medicine and Performance Center, city: Colorado Springs, state: Colorado, zip: 80918, country: United States, geoPoint lat: 38.83388, lon: -104.82136, hasResults: False