protocolSection identificationModule nctId: NCT06364891, orgStudyIdInfo id: VMMC NEXUS, briefTitle: Assessing the Impact of a Digital VMMC Platform, acronym: VMMC NEXUS, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-10-01, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-04-15, lastUpdatePostDateStruct date: 2024-04-15, sponsorCollaboratorsModule leadSponsor name: University of Alabama at Birmingham, class: OTHER, collaborators name: Centre for Infectious Disease Research in Zambia, descriptionModule briefSummary: VMMC has been identified as a crucial intervention by UNAIDS to achieve the 2030 global target of a 90% reduction in new HIV infections compared with 2010 levels. CIDRZ, a key partner to the Ministry of Health, has worked with DesireLine to develop a mobile application that supports mobilisers to segment potential clients and provide them with targeted messaging based on their segmentation type. The hypothesis of our proposed study is that targeted interventions addressing the barriers for each of the seven segments, assisted by the Digital Mobilization Tool, will better meet the needs of potential clients and therefore improve uptake of VMMC services, specifically among the three most-resistant segments.The objective of this study is to evaluate the effect of a segment-targeted mobilization intervention supported by the VMMC NEXUS Digital Mobilization Tool on the uptake of VMMC services at 30 intervention sites, compared with 30 control sites.The research questions are:1. What is the effect of segment-targeted mobilization interventions designed to address the specific psycho-behavioral barriers each of the seven segments face, supported by the VMMC NEXUS Digital Mobilization Tool, on the overall numbers of men receiving VMMC in each site?2. What is the effect of the same on the numbers of men by segment receiving VMMC in each site?3. What is the effect of the same on the numbers of men by age receiving VMMC in each site?Secondary goals will be the following, to the extent possible:* Assess the incremental cost of the intervention, including by MC* Assess and document process learnings from the intervention* Develop a workplan to enable national and regional scale-up of the mobilization model and NEXUS Digital Mobilization Tool if demonstrated as effective, conditionsModule conditions: Voluntary Medical Male Circumcision, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Cluster randomised control study, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 2000, type: ESTIMATED, armsInterventionsModule interventions name: VMMC NEXUS Digital application, outcomesModule primaryOutcomes measure: Total number of VMMC's conducted in intervention vs control, primaryOutcomes measure: Total number of VMMC's by segment, primaryOutcomes measure: Total number of VMMC's by age, secondaryOutcomes measure: Costing, secondaryOutcomes measure: Process evaluation, secondaryOutcomes measure: Develop a workplan and handbook to allow for the intervention to be scaled up elsewhere., eligibilityModule sex: MALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ministry of Health facilities, status: RECRUITING, city: Lusaka, zip: 10101, country: Zambia, contacts name: Carolyn Moore, role: CONTACT, phone: 0966841034, email: carolyn.bolton@cidrz.org, geoPoint lat: -15.40669, lon: 28.28713, hasResults: False