protocolSection identificationModule nctId: NCT06326957, orgStudyIdInfo id: 334979 V1 15/01/2024, secondaryIdInfos id: NIHR302904, type: OTHER_GRANT, domain: National Institute for Health & Care Research (NIHR), secondaryIdInfos id: 24/LO/0142, type: OTHER, domain: Research Ethics Committee (REC), briefTitle: Reducing Chronic Breathlessness in Adults by Following a Self-guided, Internet Based Supportive Intervention (SELF-BREATHE), acronym: SELF-BREATHE, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2028-02, completionDateStruct date: 2028-07, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-25, sponsorCollaboratorsModule leadSponsor name: King's College Hospital NHS Trust, class: OTHER, descriptionModule briefSummary: Background:Some health conditions make breathing difficult and uncomfortable. When this happens every day, it is called chronic breathlessness. Over 3 million people living with heart and lung disease have chronic breathlessness in the UK.Breathlessness is very difficult for patients themselves and their families, resulting in disability and feelings of fear, distress, and isolation. Due a to lack of supportive breathlessness services many patients frequently attend hospital Accident and Emergency (A\&E) departments seeking help.Given the on-going challenges faced by the National Health Service (NHS) in the United Kingdom, such as long waiting times, staff shortages, increased demand for services because of the COVID-19 pandemic, there is an urgent need to develop new ways to support those living with chronic breathlessness. One potential solution is to offer support online, as it is estimated that in the UK, 7 out of every 10 people with chronic breathlessness are internet users.With the help of patients and NIHR funding the research team lead by Dr Charles Reilly, developed an online breathlessness supportive website called SELF-BREATHE. SELF-BREATHE provides information and self-management tools such as breathing exercises, that patients can do at home themselves.SELF-BREATHE has been tested as part of its development. SELF-BREATHE is acceptable and valued by patients. But what is unknown is whether SELF-BREATHE improves patients' breathlessness and their life? This is the question this research seeks to answer.Aims1. To test if using SELF-BREATHE for six-weeks improves patients' breathlessness, their quality of life and whether SELF-BREATHE should be offered within the NHS2. To see if patients opt to continue to use SELF-BREATHE after six-weeks and what benefits this may have for patients.MethodsThe research team are undertaking a randomised controlled trial. For this, 246 people living with chronic breathlessness will be recruited in to this study. Each person will be randomly chosen by a computer to continue with their usual care or their usual care plus access to SELF-BREATHE. All study participants will complete questionnaires at the start of the study, thereafter at seven and twelve weeks after randomisation.These questionnaires will ask patients about 1) their breathlessness and its effect on their life and 2) planned and unplanned hospital visits. At the end of the study, we will compare answers to these questionnaires between the two groups at seven and 12 weeks.This will tell if SELF-BREATHE improved patients' breathlessness and reduced their need for unplanned hospital visits e.g., A\&E attendances due to breathlessness., conditionsModule conditions: Chronic Obstructive Pulmonary Disease, conditions: Bronchiectasis, conditions: Interstitial Lung Disease, conditions: Lung Cancer, conditions: Asthma, conditions: Dyspnea, conditions: Fibrotic Lung Disease, conditions: Chronic Lung Disease, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: A statistician blind, whoMasked: INVESTIGATOR, enrollmentInfo count: 246, type: ESTIMATED, armsInterventionsModule interventions name: SELF-BREATHE, outcomesModule primaryOutcomes measure: Numerical Rating Scale (NRS) Worst Breathlessness, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 110 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: King's College Hospital NHS Foundation Trust, city: London, zip: MK40 4DG, country: United Kingdom, contacts name: Charles C Reilly, role: CONTACT, phone: 00442032998062, email: charles.reilly@nhs.net, geoPoint lat: 51.50853, lon: -0.12574, hasResults: False