protocolSection identificationModule nctId: NCT06297265, orgStudyIdInfo id: 1B-23-2, secondaryIdInfos id: NCI-2023-10828, type: REGISTRY, domain: CTRP (Clinical Trial Reporting Program), secondaryIdInfos id: 1B-23-2, type: OTHER, domain: USC / Norris Comprehensive Cancer Center, secondaryIdInfos id: P30CA014089, type: NIH, link: https://reporter.nih.gov/quickSearch/P30CA014089, briefTitle: Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2026-04-01, completionDateStruct date: 2027-04-01, studyFirstPostDateStruct date: 2024-03-07, lastUpdatePostDateStruct date: 2024-03-07, sponsorCollaboratorsModule leadSponsor name: University of Southern California, class: OTHER, collaborators name: National Cancer Institute (NCI), descriptionModule briefSummary: This phase II trial evaluates manual lymphatic drainage breast massage for reducing treatment-related side effects in women undergoing radiation therapy after breast conserving surgery for breast cancer that has not spread to other parts of the body (localized). Breast conserving surgery can be an effective treatment option for early stage breast cancer, but it can also be associated with side effects including fluid collection in tissues/swelling (lymphedema), pain, reduced quality of life, and poorer body image. Manual lymphatic drainage is a gentle massage technique used to reduce swelling. It may be a safe and effective way to reduce treatment-related side effects in women receiving radiation therapy after surgery for localized breast cancer., conditionsModule conditions: Anatomic Stage 0 Breast Cancer AJCC v8, conditions: Anatomic Stage IA Breast Cancer AJCC v8, conditions: Localized Breast Carcinoma, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Lymphedema Management, interventions name: Questionnaire Administration, interventions name: Adjuvant breast radiation therapy, outcomesModule primaryOutcomes measure: Rate of compliance of MLD breast massage sessions, secondaryOutcomes measure: Assess the effect of MLD breast massage breast edema, secondaryOutcomes measure: Assess the effect of MLD breast massage on pain, secondaryOutcomes measure: Assess the effect of MLD breast massage on functional status, secondaryOutcomes measure: Assess the effect of MLD breast massage on quality of life, secondaryOutcomes measure: Assess the effect of MLD breast massage on body image, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: USC / Norris Comprehensive Cancer Center, city: Los Angeles, state: California, zip: 90033, country: United States, contacts name: Kimberly Arieli, RN, role: CONTACT, phone: 323-865-0451, email: Kimberly.Arieli@med.usc.edu, contacts name: May L. Tao, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 34.05223, lon: -118.24368, hasResults: False