hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06357494, orgStudyIdInfo id: Thyroid Doppler in Graves', briefTitle: Assessment of Thyroid Doppler Ultrasound in Followup of Pediatric Graves' Disease, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-05, primaryCompletionDateStruct date: 2027-04-05, completionDateStruct date: 2028-04-05, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: All cases of the study will be diagnosed as Graves' by History, examination, laboratory (FT3, FT4, TSH \& TRAbs), X-ray on left wrist for bone age, neck grey scale ultrasonography for thyroid gland size, shape, echotexture, vascularity and nodule characters if present with TIRAD score calculation.Then Color flow doppler ultrasound will be done to asses thyroid volume, number of vessels per square cm and inferior thyroid artery peak systolic velocity, end diastolic velocity and resistive index. Patients then will receive carbimazole antithyroid drug at dose 0.25-0.5 mg/kg/day PO \& the dose will be titrated according to thyroid function test after 4-6 weeks.Beta-adrenergic blockade will be added to all symptomatic cases. Regular follow up will be done every month of first 3 months of diagnosis and then every 3 months for 2 years by clinical and thyroid function test to asses response, compliance, complications, drug side effects, remission and relapses.Doppler ultrasound will be done at 0, 12 and 24 months., conditionsModule conditions: Doppler Ultrasound in Follow up of Graves' Patients, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 32, type: ESTIMATED, outcomesModule primaryOutcomes measure: To make follow up of graves disease easier and improve patients adherence to treatment and follow up plan., secondaryOutcomes measure: better control of disease in our patients, less complications, less mortality and better prognosis., eligibilityModule sex: ALL, minimumAge: 1 Year, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06357481, orgStudyIdInfo id: SaglikBilimleriU-22-122, briefTitle: Evaluation of Postoperative Pain After Single Visit Retreatment of Symptomatic and Asymptomatic Teeth, acronym: Endodontics, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-01-26, primaryCompletionDateStruct date: 2023-01-30, completionDateStruct date: 2024-01-28, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Saglik Bilimleri Universitesi, class: OTHER, descriptionModule briefSummary: Introduction: The aim of this study comparing the post operative pain after the retreatment of asymptomatic and symptomatic teeth that during single visit treatment with rotary and reciprocal nickel titanium files.Methods: One hundred and forty one patients scheduled for non-surgical endodontic retreatment were included for evaluation. Eighty five patients who needed endodontic retreatment were assingned to 2 groups according to semptomatic or asemptomatic teeth and 4 subgroups with rotary and resiprocal files. Endodontic filling material was removed with One Flare and MicroMega REMOVER files in the retreatment kit. Patients then recorded their postoperative pain on a VAS scale at 24h, 48h, 72h, 7 days and 14 days post-treatment. Results were analyzed using the Shapiro-Wilk, Mann-Whitney U, Kruskal-Wallis, Dunn-Bonferroni and Pearson Chi-square tests., conditionsModule conditions: Post-operative Pain, conditions: Retreatment, conditions: Symptomatic Periapical Periodontitis, conditions: Endodontic Disease, conditions: Asymptomatic Periapical Periodontitis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Eighty patients who needed endodontic retreatment were assingned to 2 groups according to symptomatic or asymptomatic teeth and 4 subgroups with rotary and resiprocal files., primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 80, type: ACTUAL, armsInterventionsModule interventions name: Endodontic Retreatment, outcomesModule primaryOutcomes measure: Post-operative pain, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 67 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hüseyin Gürkan Güneç, city: Istanbul, state: Uskudar, zip: 34450, country: Turkey, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06357468, orgStudyIdInfo id: UKGEB003, briefTitle: Analysis of Pain Management and Pain Perception Intrapartum and Postpartum in Women With Vaginal Births in Difference Between Physician-led and Midwife-led Birth, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-01-01, primaryCompletionDateStruct date: 2024-06-30, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Martin-Luther-Universität Halle-Wittenberg, class: OTHER, descriptionModule briefSummary: The aim of the analysis is to describe the differences and similarities in obstetric pain management and pain perception intrapartum and postpartum in women with vaginal births in contrast to physician-led births and midwife-led births, conditionsModule conditions: Pain, Labor, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 400, type: ESTIMATED, armsInterventionsModule interventions name: midwife-led births in low risk women in pregnancy, outcomesModule primaryOutcomes measure: Pain perception, secondaryOutcomes measure: Satisfaction with pain therapy, secondaryOutcomes measure: Pain perception in women with perineal tear grade III, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University Hospital of Halle, status: RECRUITING, city: Halle, state: Saxony Anhalt, zip: 06120, country: Germany, contacts name: Marcus Riemer, MD, role: CONTACT, phone: 03455573946, email: marcus.riemer@uk-halle.de, geoPoint lat: 51.48159, lon: 11.97948, hasResults: False
protocolSection identificationModule nctId: NCT06357442, orgStudyIdInfo id: 23-2305, briefTitle: Assessment of Endometrial Thickness Among Adolescent and Young Adult Patients on Estrogen Replacement Therapy Using Daily Oral Micronized Progesterone Versus the Etonogestrel Implant., statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-04, completionDateStruct date: 2025-04, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: University of Colorado, Denver, class: OTHER, descriptionModule briefSummary: The goal of this observational study is to compare endometrial stripe thickness in adolescent and young adult (AYA) patients with a uterus on estrogen replacement therapy using oral progesterone versus the etonogstrel implant for endometrial protection.The main questions it aims to answer are:Aim 1: Characterize the mean endometrial thickness in AYA on estrogen hormone replacement therapy before initiation of progesterone therapyAim 2: Characterize the mean changes and variability in endometrial thickness in AYA treated for 6 months with either the etonogestrel implant or continuous oral progesteroneAim 3: Assess satisfaction, side effects, bleeding patterns, any progesterone modifications, and adherence in AYA treated for 6 months with either etonogestrel implant or continuous progesteroneParticipants will be asked to:* Get two pelvic ultrasounds* Fill out two surveys* Continue their current hormone replacement therapy* Initiate one of two progesterone therapies (prometrium 100mg daily or Nexplanon)Researchers will compare the change in endometrial thickness after 6 months of progesterone use to see if there is a significant difference in the mean change between the prometrium and Nexplanon groups., conditionsModule conditions: Primary Ovarian Insufficiency, conditions: Hypogonadotropic Hypogonadism, conditions: Hormone Replacement Therapy, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 34, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Mean change in endometrial thickness after 6 months of progesterone therapy, secondaryOutcomes measure: Measure the mean endometrial thickness on estrogen replacement therapy, otherOutcomes measure: Satisfaction of progesterone replacement therapy, otherOutcomes measure: Bleeding patterns on progesterone replacement therapy, otherOutcomes measure: Side effects of progesterone replacement therapy, otherOutcomes measure: Adherence to progesterone replacement therapy, otherOutcomes measure: Rate of enrollment and attrition, otherOutcomes measure: Number of patients willing to be randomized in future trial, eligibilityModule sex: FEMALE, minimumAge: 12 Years, maximumAge: 25 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06357429, orgStudyIdInfo id: 171002100, briefTitle: Evaluation of the Effect of the LI4 Cold Application, acronym: LI4, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-02-23, primaryCompletionDateStruct date: 2022-11-18, completionDateStruct date: 2022-11-18, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Saglik Bilimleri Universitesi, class: OTHER, descriptionModule briefSummary: It is an experimental study conducted to evaluate the effectiveness of cold application to the LI4 point of the hand to reduce/eliminate pain, nausea and anxiety in postoperative patients. The population of the study consisted of 116 individuals who underwent abdominal surgery with the open surgery method in a state hospital between February 2022 and November 2022 and were followed up in the inpatient ward. The study was completed with 80 individuals constituting the experimental group (n=40) and the control group (n=40). Patient information form, Mcgill Melzack short pain form, Visual Analog Scale, STAI - TX and Cold Application Evaluation Form were used to collect data. Patients in the experimental group underwent cold application with ice cubes for a total of 20 minutes as 2 minutes of cold application and 15 seconds of waiting 4-6 hours after the patient was admitted to the clinic after surgical intervention. Follow-up was performed before cold application, immediately after cold application, 30 minutes after the end of cold application, 1 hour and 2 hours after the end of cold application., conditionsModule conditions: Pain, conditions: Nausea, conditions: Anxiety, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 80, type: ACTUAL, armsInterventionsModule interventions name: Cold Application, outcomesModule primaryOutcomes measure: Pain Level, primaryOutcomes measure: Nausea Level, primaryOutcomes measure: Anxiety Level, primaryOutcomes measure: Sensory characteristics, intensity and impact of pain, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Saglik Bilimleri University, city: Istanbul, state: Uskudar, zip: 34674, country: Turkey, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06357390, orgStudyIdInfo id: 202106174RINB, briefTitle: Physiologic and Clinical Effect of High-flow Oxygen Therapy in Tracheostomized Patients With Prolonged Mechanical Ventilation Undergoing Weaning Trials, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-10-07, primaryCompletionDateStruct date: 2022-07-25, completionDateStruct date: 2024-02-15, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: National Taiwan University Hospital, class: OTHER, descriptionModule briefSummary: This study is aimed at patients who have been admitted to the respiratory care center of this hospital who meet the PMV conditions (defined as continuous use of the ventilator for at least ten days) who are about to receive the ventilator out of training. After obtaining the explanatory consent, they will undergo continuous complete Before and after spontaneous breathing training, collect various relevant physiological data of lung volume and ventilation perfusion distribution, and analyze and predict the correlation of ventilator detachment., conditionsModule conditions: High Flow Oxygen Therapy, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 10, type: ACTUAL, outcomesModule primaryOutcomes measure: ventilation perfusion distribution measurement, eligibilityModule sex: ALL, minimumAge: 20 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: National Taiwan University Hospital, city: Taipei, country: Taiwan, geoPoint lat: 25.04776, lon: 121.53185, hasResults: False
protocolSection identificationModule nctId: NCT06357377, orgStudyIdInfo id: NEO100-03, briefTitle: A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2024-10-31, completionDateStruct date: 2024-10-31, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Neonc Technologies, Inc., class: INDUSTRY, descriptionModule briefSummary: This is an open label, Phase 1b safety, dose-finding, brain tumor delivery, and pharmacokinetics study of intranasal NEO100 in patients with pediatric-type diffuse high grade gliomas. Patients will receive IN NEO100 that will follow a dose titration design, followed by a standard dose escalation design to establish safety. Brain tumor delivery of NEO100 will be confirmed in each disease sub-type by surgical resection/needle biopsy only if clinically indicated and scheduled for clinical purposes and testing with residual tissue for NEO100 and the major metabolite of NEO100 (Perillic Acid)., conditionsModule conditions: Pediatric Tumor of CNS, conditions: Pediatric Tumor of Brain, conditions: Diffuse Midline Glioma, H3 K27M-Mutant, conditions: Pediatric Tumor of Brain Stem, conditions: Pineocytoma, conditions: Choroid Plexus Carcinoma, Childhood, conditions: Spinal Cord Tumor, conditions: High Grade Glioma, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 15, type: ESTIMATED, armsInterventionsModule interventions name: NEO100, outcomesModule primaryOutcomes measure: Nature and severity of adverse events, secondaryOutcomes measure: Identify the maximum tolerated dose (MTD) of NEO100, secondaryOutcomes measure: Determine the recommended Phase 2 dose (RP2D) of NEO100, secondaryOutcomes measure: Measurement of NEO100 and its metabolite perillic acid in brain tumor tissue, secondaryOutcomes measure: Blood brain barrier penetration, secondaryOutcomes measure: Characterize the pharmacokinetics (PK) of NEO100 as measured by Peak Plasma Concentration, secondaryOutcomes measure: Characterize the pharmacokinetics (PK) of NEO100 as measured by the Time to Peak Plasma Concentration, secondaryOutcomes measure: Characterize the pharmacokinetics (PK) of NEO100 as measured by Area Under the Curve, secondaryOutcomes measure: To assess efficacy of NEO100 based on objective response rate (ORR)., secondaryOutcomes measure: To assess efficacy of NEO100 based on progression free survival (PFS)., secondaryOutcomes measure: To assess efficacy of NEO100 based on overall survival (OS)., eligibilityModule sex: ALL, minimumAge: 5 Years, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06357351, orgStudyIdInfo id: VISTA in gingival recession, briefTitle: Comparison of Using Collagen Membrane and A-PRF Using VISTA Technique in Gingival Recession Treatment, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2022-07-01, primaryCompletionDateStruct date: 2024-04, completionDateStruct date: 2024-05, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Mansoura University, class: OTHER, descriptionModule briefSummary: To assess the efficacy of minimally invasive Vestibular Incision Subperiosteal Tunnel Access (VISTA) with collagen membrane and Advanced Platelet-rich Fibrin (A-PRF) in the treatment of multiple buccal gingival recession type 1(RT1) Cairo Classification., conditionsModule conditions: Gingival Recession, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 24, type: ACTUAL, armsInterventionsModule interventions name: vestibular incision sub periosteal tunnel access ( VISTA) technique., outcomesModule primaryOutcomes measure: Measuring the recession width in millimeter, primaryOutcomes measure: Measuring the recession depth in millimeter, primaryOutcomes measure: Measuring the width of keratinized gingiva in millimeter, primaryOutcomes measure: Mean of root coverage, secondaryOutcomes measure: Measuring the probing depth, secondaryOutcomes measure: Measuring the plaque index, secondaryOutcomes measure: Measuring the gingival index, secondaryOutcomes measure: Clinical attachment level, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule locations facility: Mansoura university, city: Mansoura, country: Egypt, geoPoint lat: 31.03637, lon: 31.38069, hasResults: False
protocolSection identificationModule nctId: NCT06357338, orgStudyIdInfo id: Soh-Med-24-03-15MS, briefTitle: Differential Expression and Potential Value of c-MYC in Non-Invasive and Invasive Mammary Carcinoma, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2024-03-19, primaryCompletionDateStruct date: 2025-04-01, completionDateStruct date: 2026-04-01, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Marwa Mahmoud Hassan, class: OTHER, collaborators name: Qena Oncology Center, descriptionModule briefSummary: Retrospective observational study to evaluate c-MYC expression in non invasive and invasive mammry carcinoma, conditionsModule conditions: Invasive Breast Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: RETROSPECTIVE, enrollmentInfo count: 70, type: ESTIMATED, armsInterventionsModule interventions name: no intervention, outcomesModule primaryOutcomes measure: role of c-MYC in breast cancer, eligibilityModule sex: FEMALE, minimumAge: 15 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Sohag university, city: Sohag, country: Egypt, geoPoint lat: 26.55695, lon: 31.69478, hasResults: False
protocolSection identificationModule nctId: NCT06357325, orgStudyIdInfo id: E-74555795-050.01.04-52290, briefTitle: 2023 Problems Faced by Women Earthquake Survivors in Kahramanmaraş, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-06-22, primaryCompletionDateStruct date: 2023-09-30, completionDateStruct date: 2023-12-01, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Maltepe University, class: OTHER, descriptionModule briefSummary: Objective:This study was conducted to evaluate the opinions of earthquake victims about the problems affecting women's health physically and psychosocially after the 2023 Kahramanmaraş earthquake.Method:The study was designed in a qualitative type (semi-structured). The population of the study consisted of women affected by the 2023 Kahramanmaraş-Pazarcık earthquake. 15 women were interviewed., conditionsModule conditions: Psychosocial Problem, conditions: Nurse-Patient Relations, conditions: Disaster; Personality, conditions: Gender, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 15, type: ACTUAL, armsInterventionsModule interventions name: a qualitative study., outcomesModule primaryOutcomes measure: Personal Information Form, primaryOutcomes measure: A semi-structured interview form, primaryOutcomes measure: consists of questions about changes experienced after the earthquake, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ozeninam, city: Istanbul, state: Maltepe, zip: 34857, country: Turkey, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06357312, orgStudyIdInfo id: 2023/11P, briefTitle: Influence of Static Distal Locking of a Short Proximal Femoral Nail, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-04-01, completionDateStruct date: 2024-04-01, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Elda University Hospital, class: OTHER, descriptionModule briefSummary: Prospective, comparative, randomized, double-blind study to evaluate the outcomes of trochanteric nailing in unstable hip fractures with and without a distal interlocking screw., conditionsModule conditions: Hip Fracture, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Prospective, comparative, randomized and double-blind study, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: Blinding of the patient included in the study and the investigator evaluating the results, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: hip trochanteric nail, outcomesModule primaryOutcomes measure: Evaluation of functional status using the Barthel index, secondaryOutcomes measure: Postoperative mechanical complications, secondaryOutcomes measure: Parker mobility scale, eligibilityModule sex: ALL, minimumAge: 50 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Elda University Hospital, status: RECRUITING, city: Elda, state: Comunidad Valenciana, zip: 03600, country: Spain, contacts name: FRANCISCO ANTONIO MIRALLES MUÑOZ, role: CONTACT, phone: 651552115, email: fr_miralles@hotmail.com, geoPoint lat: 38.47783, lon: -0.79157, hasResults: False