hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06278766, orgStudyIdInfo id: M24-416, briefTitle: A Study to Assess the Mass Balance of [14C] ABBV-552 in Healthy Male Participants Following Single Oral Dose Administration, statusModule overallStatus: COMPLETED, startDateStruct date: 2024-02-21, primaryCompletionDateStruct date: 2024-04-19, completionDateStruct date: 2024-04-19, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: AbbVie, class: INDUSTRY, descriptionModule briefSummary: The purpose of this study is to evaluate mass balance, pharmacokinetics and safety of \[14C\] ABBV-552 in healthy, male volunteers following administration of a single oral dose., conditionsModule conditions: Healthy Volunteer, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 8, type: ACTUAL, armsInterventionsModule interventions name: ABBV-552, outcomesModule primaryOutcomes measure: Number of Participants with Adverse Events (AEs), primaryOutcomes measure: Maximum observed concentration (Cmax) of ABBV-552, primaryOutcomes measure: Time to Cmax (peak time, Tmax) of ABBV-552, primaryOutcomes measure: Terminal phase elimination rate constant (λz) of ABBV-552, primaryOutcomes measure: Terminal phase elimination half-life (t1/2) of ABBV-552, primaryOutcomes measure: Area under the plasma concentration-time curve (AUC) from time 0 to the time of the last measurable concentration (AUCt) of ABBV-552, primaryOutcomes measure: Area under the plasma concentration-time curve (AUC) from time 0 to infinite time (AUCinf) of ABBV-552, primaryOutcomes measure: Amount of ABBV-552 excreted in the urine over the sampling period (Aeu), primaryOutcomes measure: Percent of ABBV-552 excreted in the urine, primaryOutcomes measure: Renal clearance ABBV-552 (CLr), primaryOutcomes measure: Amount of ABBV-552 excreted in the feces over the sampling period (Aef), primaryOutcomes measure: Percent radioactivity excreted in the feces, eligibilityModule sex: MALE, minimumAge: 18 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule locations facility: Fortrea Clinical Research Unit Inc /ID# 262684, city: Madison, state: Wisconsin, zip: 53704, country: United States, geoPoint lat: 43.07305, lon: -89.40123, hasResults: False
protocolSection identificationModule nctId: NCT06278753, orgStudyIdInfo id: 2025/05/02, briefTitle: Comparison of Standard Cystoscopy With Carbon Dioxide Cystoscopy, statusModule overallStatus: RECRUITING, startDateStruct date: 2021-07-01, primaryCompletionDateStruct date: 2024-03-01, completionDateStruct date: 2024-04-01, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Tepecik Training and Research Hospital, class: OTHER, descriptionModule briefSummary: For the evaluation of the lower urinary tract after laparoscopic hysterectomy, routine standard saline cystoscopy and carbon dioxide cystoscopy will be compared., conditionsModule conditions: Bladder Injury, conditions: Ureter Injury, conditions: Surgical Injury, conditions: Complication of Surgical Procedure, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: carbon dioxide cystoscopy, outcomesModule primaryOutcomes measure: It was aimed to evaluate the effectiveness and reliability of carbon dioxide cystoscopy., secondaryOutcomes measure: It was aimed to evaluate the speed and image quality of carbon dioxide cystoscopy in detecting intravesical masses., eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 90 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Tepecik Training and Research Hospital, status: RECRUITING, city: İzmir, state: Eurasia, zip: 35090, country: Turkey, contacts name: Ali Turgut, role: CONTACT, phone: 02324696969, email: iyikliniktepecikeah@gmail.com, geoPoint lat: 38.41273, lon: 27.13838, hasResults: False
protocolSection identificationModule nctId: NCT06278740, orgStudyIdInfo id: SCIUSG24, briefTitle: Upper Extremity Pathologies in Spinal Cord Injuries, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-02-26, primaryCompletionDateStruct date: 2025-02-26, completionDateStruct date: 2025-03-26, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Afyonkarahisar Health Sciences University, class: OTHER, descriptionModule briefSummary: This study aims to determine the relationship between upper extremity pathologies and demographic data, duration of manual wheelchair use, duration of injury, physical examination and musculoskeletal ultrasound measurements in patients with spinal cord injuries., conditionsModule conditions: Spinal Cord Injuries, conditions: Upper Extremity Problem, conditions: Musculoskeletal Pain, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 174, type: ESTIMATED, armsInterventionsModule interventions name: Musculoskeletal Ultrasound, outcomesModule primaryOutcomes measure: Comparison of US findings among participants, secondaryOutcomes measure: Visual Analog Scale (VAS), secondaryOutcomes measure: The Physical Examination of the Shoulder Scale (PESS), secondaryOutcomes measure: The Quick Disability of the Arm, Shoulder, and Hand (Quick DASH), secondaryOutcomes measure: American Spinal Injury Association (ASIA) Impairment Scale, secondaryOutcomes measure: The Spinal Cord Independence Measure (SCIM-III), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Afyonkarahisar Health Sciences University, city: Afyonkarahisar, zip: 03100, country: Turkey, contacts name: Mahmut Sami DOĞANLAR, MD, role: CONTACT, phone: +905512579828, email: mahmutdoganlar96@gmail.com, contacts name: Nuran EYVAZ, MD, role: CONTACT, phone: +905334262442, email: eyvaznuran@gmail.com, geoPoint lat: 38.75667, lon: 30.54333, hasResults: False
protocolSection identificationModule nctId: NCT06278727, orgStudyIdInfo id: SYSKY-2023-1173-01, briefTitle: Development and Validation of the Prediction Model for Functional Mitral Regurgitation Regression in Heart Failure Patients Taking Guideline-directed Medical Therapy, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2025-06-01, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, class: OTHER, descriptionModule briefSummary: This observational study is to develop and validate the prediction model for functional mitral regurgitation regression in heart failure patients taking GDMT. The patients diagnosed ≥2+ functional mitral regurgitation by ultrasonic cardiogram are enrolled in this study and would be clinically followed by at least one year (clinical visit at 3 months, 6 months, and 12 months), and then by when the endpoints are reached., conditionsModule conditions: Mitral Regurgitation, conditions: Heart Failure, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 270, type: ESTIMATED, armsInterventionsModule interventions name: angiotensin-converting enzyme inhibitors/angiotensin II receptor blocker/angiotensin receptor-neprilysin inhibitor, interventions name: The development of the prediction model, outcomesModule primaryOutcomes measure: FMR regression rate, secondaryOutcomes measure: FMR regression rate, secondaryOutcomes measure: composite endpoint, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Sun-Yatsen Memorial Hospital, status: RECRUITING, city: Canton, state: Guangdong, country: China, contacts name: Maohuan Lin, role: CONTACT, geoPoint lat: 23.11667, lon: 113.25, hasResults: False
protocolSection identificationModule nctId: NCT06278714, orgStudyIdInfo id: 0012, briefTitle: Influence of an Inspiratory Muscle Fatigue Protocol on Healthy Youngs on Respiratory Muscle Strength and Heart Rate Variability, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-04, primaryCompletionDateStruct date: 2024-03-11, completionDateStruct date: 2024-03-20, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Sierra Varona SL, class: OTHER, collaborators name: Universidad Europea de Madrid, descriptionModule briefSummary: Respiratory muscle training represents an effective method increasingly utilized in both sports and healthcare domains, employing various devices, among which threshold devices are prominent. The aim of this study is to determine the relationship between inspiratory muscle fatigue and maximal inspiratory pressure, diaphragmatic strength (guided by ultrasound image) and heart rate variability.According to our hypothesis, the execution of a protocol inducing inspiratory muscle fatigue in healthy youngs could influence cardiorespiratory function.In this study, subjects will be divided into three groups: the experimental group, the activation group and the control group.Measurements of variables, such as maximal inspiratory pressure, heart rate variability and diaphragmatic strength (ultrasound image), will be conducted., conditionsModule conditions: Healthy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: the outcome assessor will not know in which group is each participant, and the investigator will receive the data without knowing which data is from which group, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 18, type: ESTIMATED, armsInterventionsModule interventions name: Inspiratory muscle training, outcomesModule primaryOutcomes measure: Respiratory muscle strength, primaryOutcomes measure: Diaphragmatic thickness and thickening fraction, primaryOutcomes measure: Diaphragm movement curve, primaryOutcomes measure: Heart rate variability, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06278675, orgStudyIdInfo id: SEOVA, briefTitle: Multiple Study of Electroaccpuncture in ARDS, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-10, primaryCompletionDateStruct date: 2026-06-30, completionDateStruct date: 2026-12-31, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Nanjing University of Traditional Chinese Medicine, class: OTHER, descriptionModule briefSummary: In order to clarify the clinical efficacy of electroacupuncture on inhibiting systemic inflammatory response, improving respiratory mechanics parameters and prognosis in patients with sepsis-related ARDS., conditionsModule conditions: Acute Respiratory Distress Syndrome, conditions: Sepsis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: INVESTIGATOR, enrollmentInfo count: 264, type: ESTIMATED, armsInterventionsModule interventions name: Acupuncture needles, outcomesModule primaryOutcomes measure: Respiratory mechanics indicators 1, primaryOutcomes measure: Respiratory mechanics indicators 2, primaryOutcomes measure: Respiratory mechanics indicators 3, primaryOutcomes measure: Respiratory mechanics indicators 4, primaryOutcomes measure: Respiratory mechanics indicators 5, primaryOutcomes measure: Respiratory mechanics indicators 6, primaryOutcomes measure: Respiratory mechanics indicators 7, secondaryOutcomes measure: Sedation and analgesia, secondaryOutcomes measure: Sedative drug use, secondaryOutcomes measure: Analgesic drug use, secondaryOutcomes measure: Inflammatory factors, secondaryOutcomes measure: CD4、CD8、CD4/CD8, secondaryOutcomes measure: Vasoactive drugs applications, secondaryOutcomes measure: CRRT applications, secondaryOutcomes measure: ECMO applications, secondaryOutcomes measure: All-cause mortality to day 28, secondaryOutcomes measure: All-cause mortality to day 60, secondaryOutcomes measure: ICU-free days, secondaryOutcomes measure: Hospital-free days, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, city: Nanjing, state: Jiangsu, zip: 210029, country: China, contacts name: Jun Lu, Doctor, role: CONTACT, phone: +86 13813865758, email: lujun@njucm.edu.cn, geoPoint lat: 32.06167, lon: 118.77778, hasResults: False
protocolSection identificationModule nctId: NCT06278649, orgStudyIdInfo id: 2023-161-Multi-site, briefTitle: Relaxation and Guided Imagery as an Intervention for Asthma, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09-01, primaryCompletionDateStruct date: 2026-01-01, completionDateStruct date: 2026-01-01, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Pace University, class: OTHER, collaborators name: University of Connecticut, collaborators name: Touro University, descriptionModule briefSummary: The purpose of the current study is to investigate the usefulness of a Relaxation and Guided Imagery intervention for the reduction of asthmatic symptoms in adults and children whose asthma symptoms are aggravated, or triggered by anxiety. This study will replicate the previous literature to further investigate the impact that a Relaxation and Guided Imagery intervention can have on anxiety and related asthmatic symptoms using a multiple baseline (small sample size) research design. Participants will fill out questionnaires, listen to RGI audio tapes, and provide lung functioning samples by blowing into a spirometer., conditionsModule conditions: Asthma, conditions: Anxiety, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 5, type: ESTIMATED, armsInterventionsModule interventions name: Relaxation and Guided Imagery, outcomesModule primaryOutcomes measure: Asthma, primaryOutcomes measure: Asthma, primaryOutcomes measure: Anxiety, secondaryOutcomes measure: Quality of Life, eligibilityModule sex: ALL, minimumAge: 8 Years, maximumAge: 80 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06278636, orgStudyIdInfo id: 5745, briefTitle: Laparoscopic Ultrasound Examination: Analysis of Feasibility, acronym: LUXA, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-07-18, primaryCompletionDateStruct date: 2024-12-30, completionDateStruct date: 2025-01-30, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, class: OTHER, descriptionModule briefSummary: This is a prospective cohort study to assess the feasibility of the laparoscopic ultrasound examination, directly by surgeons, during minimally invasive gynaecological surgery.The secondary aims are to examine the learning curve for laparoscopic ultrasound examination and the performance score in obtaining high quality ultrasound images of anatomical parameters by a team of 5 gynecological laparoscopic fellows. The patients' medical history and symptoms will also be recorded to define whether these clinical data can influence the failure rate. With advanced technology, the conventional workflow can be simplified by using laparoscopic ultrasound probes directly by surgeons, to utilize the hospital resources efficiently and to reduce operating times. In this regard, we would like to demonstrate that the application of laparoscopic examination is feasible and easy to learn by surgeons. This innovative technique could open up multiple diagnostic and therapeutic opportunities for the patient, providing potential clinical information useful to the surgeon., conditionsModule conditions: Gynecologic Cancer, conditions: Surgical Procedure, Unspecified, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 300, type: ESTIMATED, armsInterventionsModule interventions name: Laparoscopi ultrasound examination, outcomesModule primaryOutcomes measure: feasibility of the laparoscopic, secondaryOutcomes measure: the learning curve of fellow surgeons, secondaryOutcomes measure: the performance of fellow surgeons, eligibilityModule sex: FEMALE, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, status: RECRUITING, city: Rome, zip: 00168, country: Italy, contacts name: Floriana Mascilini, Dr, role: CONTACT, contacts name: Antonia Carla Testa, Prof, role: CONTACT, contacts name: Floriana Mascilini, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 41.89193, lon: 12.51133, hasResults: False
protocolSection identificationModule nctId: NCT06278623, orgStudyIdInfo id: 4935, briefTitle: Focal Muscle Vibration in Parkinson's Disease, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-05-11, primaryCompletionDateStruct date: 2025-12-01, completionDateStruct date: 2025-12-01, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, class: OTHER, descriptionModule briefSummary: Postural instability has a major impact on the mobility and daily life activities of Parkinson's disease (PD) patients as it often leads to reduced mobility, insecure stance and falls.The aim of this study was to evaluate the effect of focal vibration on the static and dynamic balance of a group of Parkinson's disease patients with Hoehn and Yahr (HeY) stage II-III. They underwent three weeks of focal muscle vibration applied to the quadriceps, soles of the feet and trapezius muscles bilaterally in addition to conventional physiotherapy . The static and dynamic balance was assessed at baseline (T0), after 3 weeks of treatment (T1) and after 1 month from the last treatment (T2) with the Tinetti scale and stabilometry evaluations., conditionsModule conditions: Parkinson Disease, conditions: Postural; Defect, conditions: Rehabilitation, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 23, type: ESTIMATED, armsInterventionsModule interventions name: Focal Muscle Vibratory Energy (EVM) Treatment, outcomesModule primaryOutcomes measure: Tinetti scale, secondaryOutcomes measure: NRS numeric rating scale of pain, secondaryOutcomes measure: Stabilometric Test, secondaryOutcomes measure: Mc Gill Pain questionnaire, eligibilityModule sex: ALL, minimumAge: 18 Months, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Gianpaolo Ronconi, status: RECRUITING, city: Roma, zip: 00168, country: Italy, contacts name: gianpaolo ronconi, role: CONTACT, phone: +393477123940, email: gronconi@yahoo.it, geoPoint lat: 41.89193, lon: 12.51133, hasResults: False
protocolSection identificationModule nctId: NCT06278610, orgStudyIdInfo id: 3612, briefTitle: Pelvic Exenteration and Laterally Extended Pelvic Resection, acronym: Pre-PEX, statusModule overallStatus: RECRUITING, startDateStruct date: 2020-11-19, primaryCompletionDateStruct date: 2024-12-30, completionDateStruct date: 2025-01-31, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, class: OTHER, descriptionModule briefSummary: Growing evidence in literature is supporting the role of ultrasound scan (US) as accurate tool in diagnosis and staging of gynecologic cancers. In particular, different studies demonstrated the accuracy of US in assessing endometrial, cervical, and ovarian cancer in the primary setting. However, the number of studies investigating the role of US in the recurrent setting is limited. Moreover, there is no evidence in literature exploring the role of US in laterally-extended pelvic recurrences from gynecologic cancer, where the Magnetic Resonance Imaging (MRI) scan is still considered the most accurate tool., conditionsModule conditions: Gynecologic Cancer, conditions: Surgical Procedure, Unspecified, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 85, type: ESTIMATED, armsInterventionsModule interventions name: PELVIC EXENTERATION, outcomesModule primaryOutcomes measure: pelvic exenteration resection., secondaryOutcomes measure: accuracy of US with the accuracy of MRI, eligibilityModule sex: FEMALE, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, status: RECRUITING, city: Roma, zip: 00168, country: Italy, contacts name: ANTONIA CARLA Pr TESTA, role: CONTACT, email: antoniacarla.testa@policlinicogemelli.it, contacts name: NICOLO' DR BIZZARRI, role: CONTACT, phone: 3471771680, email: nicolo.bizzarri@policlinicogemelli.it, geoPoint lat: 41.89193, lon: 12.51133, documentSection largeDocumentModule largeDocs typeAbbrev: Prot, hasProtocol: True, hasSap: False, hasIcf: False, label: Study Protocol, date: 2020-05-29, uploadDate: 2023-02-24T13:07, filename: Prot_000.pdf, size: 598158, hasResults: False