hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06354894, orgStudyIdInfo id: MACOXS, secondaryIdInfos id: 133/2020/U, type: REGISTRY, domain: MACOXS, briefTitle: Percutaneous Pinning Versus Plate and Screws for Surgical Fixation of Proximal Humeral Fractures, statusModule overallStatus: RECRUITING, startDateStruct date: 2020-11-01, primaryCompletionDateStruct date: 2024-11-01, completionDateStruct date: 2024-11-01, studyFirstPostDateStruct date: 2024-04-09, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: University of Turin, Italy, class: OTHER, descriptionModule briefSummary: The aim of this multicenter nonrandomised study is to prospectively compare the clinical and radiographic results of two different techniques of surgical fixation of proximal humeral fractures: percutaneous pinning versus plate and screws., conditionsModule conditions: Proximal Humeral Fractures, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: Proximal humeral fracture fixation, outcomesModule primaryOutcomes measure: Oxford Shoulder Score (OSS), primaryOutcomes measure: Quick Disabilities of the arm, shoulder and hand (DASH) score, primaryOutcomes measure: Subjective Shoulder Value (SSV), primaryOutcomes measure: Radiographic outcomes, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: San Luigi Gonzaga Hospital, status: RECRUITING, city: Orbassano, state: Turin, zip: 10043, country: Italy, contacts name: Enrico Bellato, MD, role: CONTACT, phone: +393406429207, email: enrico.bellato@unito.it, geoPoint lat: 45.00547, lon: 7.53813, hasResults: False
protocolSection identificationModule nctId: NCT06354868, orgStudyIdInfo id: NNBioEP004, briefTitle: A Study to Assess utiLity of BIoEP as an Early Prognostic Indicator for Predicting Anti-Seizure Medication (ASM) Efficacy, acronym: ECLIPSE, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06, primaryCompletionDateStruct date: 2026-12, completionDateStruct date: 2027-06, studyFirstPostDateStruct date: 2024-04-09, lastUpdatePostDateStruct date: 2024-04-12, sponsorCollaboratorsModule leadSponsor name: Neuronostics Ltd, class: INDUSTRY, collaborators name: Cornwall Partnership NHS Foundation Trust, descriptionModule briefSummary: This multisite prospective clinical study is to investigate the relationship between seizure type and frequency with the BioEP result during ASM titration in newly diagnosed patients with epilepsy, and to assess the utility of BioEP as an early prognostic indicator of ASM efficacy, conditionsModule conditions: Epilepsy, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 158, type: ESTIMATED, outcomesModule primaryOutcomes measure: The relationship between BioEP and seizure frequency., secondaryOutcomes measure: Association between the 12-month change from baseline in BioEP result and the patients reported global impression of change, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06354855, orgStudyIdInfo id: NEU-FTR-FE-04, briefTitle: "Which Type of Exercise is More Effective in Chronic Constipation?, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-02-15, primaryCompletionDateStruct date: 2024-10, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-04-09, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Necmettin Erbakan University, class: OTHER, descriptionModule briefSummary: In this study, it will be investigated whether a daily 30-minute walk or abdominal breathing exercise is more effective on chronic constipation., conditionsModule conditions: Chronic Constipation, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Two groups with a conventional therapy control group, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: The assignment of people to groups will be done by a statistician, apart from the research using a computer program. Randomization will be determined by entering the total number of cases through the program whose URL address is https://www.randomizer.org., whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 54, type: ESTIMATED, armsInterventionsModule interventions name: Group is doing breathing exercises while watching videos, interventions name: Medium pace walking group, outcomesModule primaryOutcomes measure: Visual Analog Scale (VAS), secondaryOutcomes measure: Constipation Severity Scale (CSS), otherOutcomes measure: Chronic Constipation Quality of Life Scale, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Faculty of Nezahat Keleşoğlu Health Sciences Necmettin Erbakan University, city: Konya, state: Meram, zip: 42000, country: Turkey, geoPoint lat: 37.87135, lon: 32.48464, hasResults: False
protocolSection identificationModule nctId: NCT06354842, orgStudyIdInfo id: 12345678, briefTitle: Measurement of Sweat Sodium Concentration in Patients With Chronic Kidney Disease, statusModule overallStatus: COMPLETED, startDateStruct date: 2018-10-05, primaryCompletionDateStruct date: 2020-12-11, completionDateStruct date: 2020-12-11, studyFirstPostDateStruct date: 2024-04-09, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Medical University of Vienna, class: OTHER, descriptionModule briefSummary: It has been shown that excretion of sodium and water through the skin in the form of sweat represents a regulatory mechanism of electrolyte- and fluid balance. Since patients with chronic kidney disease (CKD) exhibit increased skin sodium content, we investigated the feasibility of sweat testing as a novel experimental tool to a more complete assessment of fluid- and sodium homeostasis.In this cross-sectional feasibility study, we applied pilocarpine iontophoresis to induce sweat testing in 58 patients across various stages of CKD including patients after kidney transplantation as well as a healthy control cohort (n=6) to investigate possible effects of CKD and transplantation status on sweat rate and sodium concentration. Due to non-linear relationships, we modeled our data using polynomial regression.Decline of kidney function showed a significant association with lower sweat rates: adj R²= 0.2278, F(2, 61) = 10.29, p = 0.000141. Sweat sodium concentrations were increased in moderate CKD, however this effect was lost in end stage renal disease: adj R² = 0.3701, F(4, 59) = 10.26, p = 2.261e-06. We observed higher sweat weight in males compared to females.Diagnostic sweat analysis represents an innovative and promising noninvasive option for more thorough investigation of sodium- and fluid homeostasis in CKD patients. Lower sweat rates and higher sweat sodium concentrations represent a unique feature of CKD patients with potential therapeutic implications., conditionsModule conditions: Chronic Kidney Diseases, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 64, type: ACTUAL, armsInterventionsModule interventions name: pilocarpine iontopheresis, outcomesModule primaryOutcomes measure: Sweat sodium concentration, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Medical University of Vienna, city: Vienna, zip: 1090, country: Austria, geoPoint lat: 48.20849, lon: 16.37208, hasResults: False
protocolSection identificationModule nctId: NCT06354829, orgStudyIdInfo id: MEDICALBUM, briefTitle: Medical Images Collection Research, acronym: MEDICALBUM, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2049-04, completionDateStruct date: 2049-04, studyFirstPostDateStruct date: 2024-04-09, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Mario Negri Institute for Pharmacological Research, class: OTHER, collaborators name: Papa Giovanni XXIII Hospital, descriptionModule briefSummary: This is a not-for-profit project for the collection, archiving and reuse of magnetic resonance imaging, computed tomography and ultrasound images, and related demographic and clinical data, for research purposes only., conditionsModule conditions: Kidney Diseases, conditions: Brain Diseases, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 300, type: ESTIMATED, armsInterventionsModule interventions name: Medical imaging procedures, outcomesModule primaryOutcomes measure: Creation of a medical images collection, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Clinical Research Center for Rare Disease Aldo e Cele Daccò, city: Ranica, state: BG, zip: 24020, country: Italy, contacts name: Anna Caroli, PhD, role: CONTACT, phone: +3903545351, email: anna.caroli@marionegri.it, geoPoint lat: 45.72328, lon: 9.71335, hasResults: False
protocolSection identificationModule nctId: NCT06354816, orgStudyIdInfo id: V 2.0, 07Feb2024, briefTitle: VENLID: The Application of a 10%-Lidocaine Spray Prior to the Insertion of a Peripheral Intra-venous Catheter in Female Adults, acronym: VENLID, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2024-05, completionDateStruct date: 2024-05, studyFirstPostDateStruct date: 2024-04-09, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Krankenhaus Barmherzige Schwestern Linz, class: OTHER, descriptionModule briefSummary: Volunteers are invited to undergo 4 insertions of a peripheral intra-venous 18-gauge catheter (PIVC); 2 insertions at the the start of the study on the plantar side of the hand/vessel at the dorsum manus, 2 insertions after 2-10 hours into the forearm/cubita with and without application of a 10-% lidocaine spray (5 hubs of xylocaine 10%-pump spray; AstraZeneca BV, Zoetermeer, The Netherlands) prior to the insertion of the PIVC., conditionsModule conditions: Pain, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: prospective, randomized, double-blind, controlled trial, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Xylocaine 10% pump spray, interventions name: Saline solution isotonic 0.9% NaCl, outcomesModule primaryOutcomes measure: To demonstrate a reduction of pain caused by PIVC rated by Numerical Rating Scale (NRS), after application of a 10% lidocaine spray- Separately measured for the plantar side of the hand/vessel at the dorsum manus, and for the forearm/cubita, secondaryOutcomes measure: To measure pain caused by PIVC rated by NRS in the dominant vs. non-dominant arm, secondaryOutcomes measure: To measure pain caused by PIVC rated by NRS at the plantar side of the hand/vessel at the dorsum manus vs. at the forearm/cubita, secondaryOutcomes measure: To measure the correlation between pain caused by PIVC rated by NRS and the anticipated pain rated by NRS, secondaryOutcomes measure: To measure the correlation between pain caused by PIVC rated by NRS and the anticipated difficulty by the operator to insert the PIVC, secondaryOutcomes measure: To measure pain rated by NRS depending on success, secondaryOutcomes measure: To describe success rates and compare it, secondaryOutcomes measure: To measure the correlation between PCS and pain caused by PIVC rated by NRS, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06354803, orgStudyIdInfo id: KafrelsheikhU 30, briefTitle: Effect of Pezzi Ball on Balance in Pregnant Women, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-03-02, primaryCompletionDateStruct date: 2024-02-02, completionDateStruct date: 2024-03-03, studyFirstPostDateStruct date: 2024-04-09, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Kafrelsheikh University, class: OTHER, descriptionModule briefSummary: The effect of kinaesthetic training on performance and postural stability during pregnancy and 2 weeks postpartum, conditionsModule conditions: Postural Stability, designModule studyType: INTERVENTIONAL, phases: PHASE2, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: 45 participants with gestational age below 28 weeks, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: QUADRUPLE, maskingDescription: The drawing procedure was conducted by a researcher without disclosure to the participants, ensuring unbiased allocation. Moreover, both the assessor and statistician remained blinded throughout the assessment period, unaware of the group assignments., whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 45, type: ACTUAL, armsInterventionsModule interventions name: proprioceptive training, outcomesModule primaryOutcomes measure: change of postural stability, eligibilityModule sex: FEMALE, minimumAge: 25 Years, maximumAge: 30 Years, stdAges: ADULT, contactsLocationsModule locations facility: Faculty of physical therapy kafrelshiekh university, city: Kafr Ash Shaykh, state: Kafrelshiekh, zip: 6850001, country: Egypt, geoPoint lat: 31.11174, lon: 30.93991, hasResults: False
protocolSection identificationModule nctId: NCT06354777, orgStudyIdInfo id: EVERCOOL AF, briefTitle: REView of ProcEdural FactoRs and Outcomes After Atrial Fibrillation Ablation With Active Esophageal COOLing: A Sub-Study of the REAL AF Registry, acronym: EVERCOOL AF, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-15, primaryCompletionDateStruct date: 2024-11-30, completionDateStruct date: 2024-12-30, studyFirstPostDateStruct date: 2024-04-09, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Heart Rhythm Clinical and Research Solutions, LLC, class: OTHER, collaborators name: Attune Medical, descriptionModule briefSummary: This is a multi-center sub-study examining the effectiveness of active esophageal cooling on subjects undergoing left atrial ablation for symptomatic Paroxysmal Atrial Fibrillation or Persistent Atrial Fibrillation., conditionsModule conditions: Atrial Fibrillation, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 312, type: ESTIMATED, armsInterventionsModule interventions name: Ablation Procedure, outcomesModule primaryOutcomes measure: To measure procedural efficacy after atrial fibrillation ablation in patients treated with active esophageal cooling., primaryOutcomes measure: To measure procedural efficacy after atrial fibrillation ablation in patients treated with active esophageal cooling., primaryOutcomes measure: To measure long term safety after atrial fibrillation in patients treated with active esophageal cooling., primaryOutcomes measure: Patient reported outcomes in patients treated with active esophageal cooling., primaryOutcomes measure: Physician reported outcome post procedure with active esophageal cooling., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06354764, orgStudyIdInfo id: 8780-UC1, briefTitle: Propensity to Hospitalize Patients From the ED in European Centers., acronym: eCREAM-UC1, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09, primaryCompletionDateStruct date: 2025-09, completionDateStruct date: 2026-09, studyFirstPostDateStruct date: 2024-04-09, lastUpdatePostDateStruct date: 2024-04-11, sponsorCollaboratorsModule leadSponsor name: Mario Negri Institute for Pharmacological Research, class: OTHER, collaborators name: Astir S.r.l., collaborators name: Centre Hospitalier Universitaire Vaudois, collaborators name: Orobix Life S.r.l., collaborators name: Fondazione Bruno Kessler, descriptionModule briefSummary: The peer-to-peer comparison means center-to-center comparison, which requires adjusting for possible differences among centers to be fair and convincing. The first step to reach this goal is to develop a predictive model that accurately estimates each patient's probability of being admitted, starting from clinical conditions and boundary variables. Such a model would make it possible to calculate, for each ED, the expected hospitalization rate; that is, the hospitalization rate that would have been observed if the ED had behaved like the average of the EDs that provided the data to build the model itself. Comparing the observed hospitalization rate in the single ED with the expected rate derived from the model provides a rigorous method of comparing the department with the average performance, taking into account the characteristics of the patients treated and the conditions under which the ED operated. In other words, the predictive model represents the benchmark against which each ED is evaluated., conditionsModule conditions: Emergency Medicine, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 162000, type: ESTIMATED, armsInterventionsModule interventions name: no intervention, outcomesModule primaryOutcomes measure: Create two separate databases, primaryOutcomes measure: Multivariable models, primaryOutcomes measure: Adjusted comparison, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06354738, orgStudyIdInfo id: S66928, briefTitle: Improving Endometrial Cancer Assessment by Combining Genomic Profiling and Surgical Assessment, acronym: EUGENIE, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-01-16, primaryCompletionDateStruct date: 2028-11-01, completionDateStruct date: 2028-11-01, studyFirstPostDateStruct date: 2024-04-09, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: University Hospital, Gasthuisberg, class: OTHER, collaborators name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, collaborators name: University Medical Centre Maribor, descriptionModule briefSummary: EUGENIE is a prospective multicentre interventional study, focused on improving endometrial cancer (EC) assessment by combining the new technique of genomic profiling with surgical extra uterine disease assessment. The investigators aim to correlate EC stage to each of the molecular subgroups of disease and thereby guide surgical treatment and staging of EC by determining the association between molecular classification and disease stage and evaluating if and how disease stage in each of the molecular subgroups associates with prognosis., conditionsModule conditions: Endometrial Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 1000, type: ESTIMATED, armsInterventionsModule interventions name: total hysterectomy with bilateral salpingo-oophorectomy, lymph node staging and comprehensive peritoneal staging, outcomesModule primaryOutcomes measure: Endometrial cancer stage, primaryOutcomes measure: Molecular type of endometrial cancer, secondaryOutcomes measure: Overall survival, secondaryOutcomes measure: Time to recurrence, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: UZ Gasthuisberg, Katholieke Universiteit Leuven, status: RECRUITING, city: Leuven, zip: 3000, country: Belgium, contacts name: Ayaka Wakatsuki, role: CONTACT, phone: +32 16 34 41 69, email: ayaka.wakatsuki@uzleuven.be, contacts name: Frédéric Amant, MD, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 50.87959, lon: 4.70093, hasResults: False
protocolSection identificationModule nctId: NCT06354725, orgStudyIdInfo id: 2vs4, briefTitle: Effect of Weekly Plyometric Training Frequency on Youth Female Basketball Players: A Comparison of Two vs. Four Sessions, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-11-01, primaryCompletionDateStruct date: 2024-01-20, completionDateStruct date: 2024-02-20, studyFirstPostDateStruct date: 2024-04-09, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Bruno Figueira, class: OTHER, collaborators name: Vytautas Magnus University, descriptionModule briefSummary: Players were randomly assigned to a two-times-a-week (2PLYO, n = 15) or four-times-a-week (4PLYO, n = 15) PT (Plyometric Training) group. Both groups performed the same weekly total volume of jumps during PT in addition to regular basketball training and competition. The 2PLYO group performed 240 jumps over two sessions (120 jumps per session), and the 4PLYO group performed 240 jumps over four sessions (60 jumps per session). After the eight-week intervention, all players underwent a one-week detraining period with no PT training while basketball training and competitions continued. Testing was performed at baseline (pre-test), after intervention (post-test), and after the detraining period. Players were assessed for lower body power using jump tests (countermovement jump \[CMJ\], drop-jump \[DJ\] from a 20-cm box, and horizontal jump \[HJ\]; change of direction ability using a planned agility test; and speed using a 20-m sprint and a 5-m split., conditionsModule conditions: Physical Performance, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: SINGLE, whoMasked: INVESTIGATOR, enrollmentInfo count: 30, type: ACTUAL, armsInterventionsModule interventions name: Plyometric, outcomesModule primaryOutcomes measure: Horizontal jump, secondaryOutcomes measure: CMJ, otherOutcomes measure: Drop Jump, otherOutcomes measure: Drop jump (RSI), otherOutcomes measure: Linear sprint-5m, otherOutcomes measure: Linear sprint-20m, otherOutcomes measure: Change of direction, eligibilityModule sex: FEMALE, minimumAge: 14 Years, maximumAge: 16 Years, stdAges: CHILD, contactsLocationsModule locations facility: Vytutas Magnus University, city: Kaunas, country: Lithuania, geoPoint lat: 54.90272, lon: 23.90961, hasResults: False