protocolSection identificationModule nctId: NCT06364709, orgStudyIdInfo id: 4526, secondaryIdInfos id: R01DC015516, type: NIH, link: https://reporter.nih.gov/quickSearch/R01DC015516, briefTitle: Criterion-learning Based Naming Treatment in Aphasia, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-15, primaryCompletionDateStruct date: 2028-08, completionDateStruct date: 2028-08, studyFirstPostDateStruct date: 2024-04-15, lastUpdatePostDateStruct date: 2024-04-15, sponsorCollaboratorsModule leadSponsor name: Albert Einstein Healthcare Network, class: OTHER, collaborators name: Thomas Jefferson University, collaborators name: National Institute on Deafness and Other Communication Disorders (NIDCD), descriptionModule briefSummary: Aphasia is a disorder of spoken and written language, most commonly following a stroke. It is estimated that between 2.5 and 4 million Americans are living with aphasia today. A common problem in aphasia involves difficulty retrieving known words in the course of language production and comprehension. The overarching goal of this project is to develop and test early efficacy, efficiency, and the tolerability of a lexical treatment for aphasia in multiple-session regimens that are comprised of retrieval practice, distributed practice, and training dedicated to the elicitation of correct retrievals. The aim of this work is to add to and refine the evidence base for the implementation and optimization of these elements in the treatment of production and comprehension deficits in aphasia, and make important steps towards an ultimate goal of self-administered lexical treatment grounded in retrieval practice principles (RPP) to supplement traditional speech-language therapy that is appropriate for People with Aphasia (PWA) from a broad level of severity of lexical processing deficit in naming and/or comprehension. This project cumulatively builds on prior work to develop a theory of learning for lexical processing impairment in aphasia that aims to ultimately explain why and for whom familiar lexical treatments work, and how to maximize the benefits they confer., conditionsModule conditions: Aphasia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 90, type: ESTIMATED, armsInterventionsModule interventions name: Criterion-learning practice, outcomesModule primaryOutcomes measure: Trained naming items (Experiment 1), primaryOutcomes measure: Trained naming items (Experiment 2), primaryOutcomes measure: Trained naming items (Experiment 3), primaryOutcomes measure: Trained comprehension items (Experiment 4), secondaryOutcomes measure: Trained naming items (Experiment 1), secondaryOutcomes measure: Trained naming items (Experiment 2), secondaryOutcomes measure: Untrained naming items (Experiment 2), secondaryOutcomes measure: Trained naming items (Experiment 3), secondaryOutcomes measure: Trained naming items (Experiment 4), secondaryOutcomes measure: Trained comprehension items (Experiment 4), secondaryOutcomes measure: Untrained comprehension items (Experiment 4), secondaryOutcomes measure: Treatment compliance (Experiment 2), otherOutcomes measure: Connected speech output performance, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 89 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False