hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06282783, orgStudyIdInfo id: 2024-511532-27-00, briefTitle: Studying Topiramate for Re-Activating the HIV-1 Reservoir, acronym: STAR, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09, primaryCompletionDateStruct date: 2025-04, completionDateStruct date: 2025-08, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Erasmus Medical Center, class: OTHER, descriptionModule briefSummary: Even with current HIV treatments, HIV is still a lifelong disease because it hides in some long-lasting cells in the body. One of the strategies to find a cure for HIV works by finding the virus in these cells, making it visible, and then getting rid of it. This is called the 'shock and kill' approach.So far, the drugs tested can find the virus, but they don't get rid of it completely. That's why there need to be new drugs that can do this more effectively. The Erasmus MC HIV Eradication Group (EHEG) has been testing new drugs in the lab and found a drug called topiramate can wake up the virus without harming the cells. The aim of this study is to test topiramate in people living with HIV.Most of the people that participate in HIV cure studies are men, even though most people living with HIV around the world are women. Previous research has shown that men and women might respond differently to these treatments. So, in this study, topiramate will be investigated in both men and women. This could help us find a cure that works for everyone., conditionsModule conditions: HIV-1-infection, conditions: Hiv, conditions: HIV Infections, conditions: HIV I Infection, designModule studyType: INTERVENTIONAL, phases: PHASE1, phases: PHASE2, designInfo allocation: NON_RANDOMIZED, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 12, type: ESTIMATED, armsInterventionsModule interventions name: Topiramate, outcomesModule primaryOutcomes measure: Effect of topiramate as measured by cell-associated HIV RNA, primaryOutcomes measure: Number of treatment-related adverse events as assessed by CTCAE v4.0, secondaryOutcomes measure: Influence of sex on the primary outcome measures, secondaryOutcomes measure: The effect of topiramate on the size of the HIV reservoir measured by relevant assays, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Erasmus Medical Centre, city: Rotterdam, country: Netherlands, geoPoint lat: 51.9225, lon: 4.47917, hasResults: False
protocolSection identificationModule nctId: NCT06282744, orgStudyIdInfo id: OPTIMAL Arabic version, briefTitle: Cross Cultural Adaptation, Validity and Reliability Test of the Arabic Version of the Outpatient Physical Therapy Improvement in Movement Assessment Log, acronym: OPTIMAL, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-03, completionDateStruct date: 2024-04, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: Purpose of the study:To translate, culturally adapt, and to test the validity and reliability of the Outpatient Physical Therapy Improvement in Movement Assessment Log in Arabic speaking language., conditionsModule conditions: Physical Performance, conditions: Outpatients, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 880, type: ESTIMATED, armsInterventionsModule interventions name: Outpatient physical therapy improvement in movement assessment log, outcomesModule primaryOutcomes measure: validity and reliability of the Egyptian Arabic language version of Outpatient Physical Therapy Improvement Movement Assessment Log on physical therapy outpatients., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06282731, orgStudyIdInfo id: ECKIRB1020407, briefTitle: The Changes of Urine Growth Factors Level, statusModule overallStatus: COMPLETED, startDateStruct date: 2013-05-31, primaryCompletionDateStruct date: 2016-09-01, completionDateStruct date: 2017-04-27, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: En Chu Kong Hospital, class: OTHER, descriptionModule briefSummary: The Changes of Urine Growth Factors Level in Patients With Benigh Prostate Hyperplasia after medical treatment., conditionsModule conditions: Benign Prostatic Hyperplasia, designModule studyType: INTERVENTIONAL, phases: EARLY_PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: SCREENING, maskingInfo masking: NONE, enrollmentInfo count: 74, type: ACTUAL, armsInterventionsModule interventions name: Silodosin, outcomesModule primaryOutcomes measure: Urine growth factors level, secondaryOutcomes measure: Urine growth factors level, otherOutcomes measure: Urine growth factors level, eligibilityModule sex: MALE, minimumAge: 50 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: En Chu Kong Hospital, city: New Taipei City, zip: 23702, country: Taiwan, geoPoint lat: 25.01111, lon: 121.44583, hasResults: False
protocolSection identificationModule nctId: NCT06282679, orgStudyIdInfo id: KY20220701-03, briefTitle: Clinical Observation of Botulinum Toxin A Treatment in the Treatment of Rosacea, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-04-01, primaryCompletionDateStruct date: 2024-03-01, completionDateStruct date: 2024-06-28, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Nanjing First Hospital, Nanjing Medical University, class: OTHER, descriptionModule briefSummary: the goal of this study is to study the clinical efficacy and safety of botox in the treatment of rosacea., conditionsModule conditions: Rosacea, conditions: Botulinum Toxin, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Botulinum Toxin Type A Injection [Botox], outcomesModule primaryOutcomes measure: CEA score, secondaryOutcomes measure: GAIS score, otherOutcomes measure: VISIA red zone score, otherOutcomes measure: Dermatology Quality of Life Score (DLQI), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Jie Dai, status: RECRUITING, city: Nanjing, state: Jiangsu, zip: 210006, country: China, contacts name: jie dai, role: CONTACT, phone: 02552271117, email: karry_dj@126.com, geoPoint lat: 32.06167, lon: 118.77778, hasResults: False
protocolSection identificationModule nctId: NCT06282666, orgStudyIdInfo id: KE-0254/150/2019, briefTitle: Lumbar ESPB in Hip Replacement Surgery, acronym: ESPB_HIP, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-02-19, primaryCompletionDateStruct date: 2025-02-01, completionDateStruct date: 2025-08-01, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Medical University of Lublin, class: OTHER, descriptionModule briefSummary: In this study, continuous erector spinae plane block (ESPB) will be compared to continuous epidural analgesia in patients undergoing elective hip replacement surgery. Opioid consumption, pain severity, quadriceps femoris muscle strength, ability to walk, and quality of recovery will be evaluated. Moreover, chronic pain severity in months after the hospital discharge will be assessed., conditionsModule conditions: Coxarthrosis, conditions: Pain, Postoperative, conditions: Pain, Acute, conditions: Pain, Chronic, conditions: Postoperative Pain, Chronic, conditions: Analgesia, conditions: Quality of Life, conditions: Anesthesia, conditions: Spinal, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Two groups will be randomly allocated to Epidural and ESPB (1:1), primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, maskingDescription: Participants will not be aware of the type of continuous blockade. Care providers, including doctors and nurses, will not be aware of patient allocation.Physiotherapists assessing outcomes will not be aware of patient allocation., whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Spinal anesthesia, interventions name: lumbar erector spinae plane block, interventions name: Epidural analgesia, interventions name: patient-controlled analgesia, interventions name: Timed Up and Go test, interventions name: neuropathic pain symptom inventory, interventions name: Lovett test, interventions name: Visual analog scale, interventions name: Quality of Recovery 40, interventions name: Ability to sit, stand upright, and walk, outcomesModule primaryOutcomes measure: Opiod consumtion with PCA, secondaryOutcomes measure: Pain at rest, secondaryOutcomes measure: Pain upon activity, secondaryOutcomes measure: Lovett test, secondaryOutcomes measure: TUG, secondaryOutcomes measure: QoR-40, secondaryOutcomes measure: NPSI, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 100 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: II Department of Anesthesia and Intensive Care, city: Lublin, zip: 20-081, country: Poland, contacts name: Michał A Borys, M.D. Ph.D, role: CONTACT, phone: 506350569, phoneExt: +48, email: michalborys1@gmail.com, contacts name: Paweł Kutnik, M.D., role: CONTACT, phone: 608769410, phoneExt: +48, email: pe.kutnik@gmail.com, geoPoint lat: 51.25, lon: 22.56667, hasResults: False
protocolSection identificationModule nctId: NCT06282653, orgStudyIdInfo id: Endo-ergonomics, briefTitle: Postural and Muscle Fatigue Analysis of Endodontic Residents, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-30, primaryCompletionDateStruct date: 2025-06-30, completionDateStruct date: 2025-11-01, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Universidad Europea de Madrid, class: OTHER, descriptionModule briefSummary: Musculoskeletal disorders (MSDs) are a significant occupational health problem for dentists and have been linked to a decline in quality of life, often leading to stress-related illnesses and early retirement. Poor posture, poor movement or imbalances in the neck or shoulders can lead to the three most common pain syndromes in dentistry. The objectives of this study were to evaluate the working position adopted during an endodontic procedure and to determine the perception of symptoms of musculoskeletal disorders in first and second year students of the Master in Advanced Endodontics at the European University of Madrid (UEM), using the standardised Nordic Kuorinka questionnaire supplemented by a form with socio-demographic variables. This study has a descriptive cross-sectional observational design and included 10 students selected by convenience sampling. A video camera was used to record the procedures from three different angles for a maximum of 5 minutes. The information was processed using Microsoft Excel spreadsheet software, and the video recordings were assessed using Rodgers' Muscular Fatigue Analysis (RMFA) and Rapid Upper Limb Assessment (RULA)., conditionsModule conditions: Musculoskeletal System Disease, conditions: Position Sense Disorders, conditions: Symptoms and Signs, conditions: Postural; Defect, conditions: Endodontic Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: OTHER, enrollmentInfo count: 10, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Symptom Perception, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Universidad Europea de Madrid, status: RECRUITING, city: Villaviciosa De Odón, state: Madrid, country: Spain, contacts name: Antonio Conde, PhD, role: CONTACT, geoPoint lat: 40.35692, lon: -3.90011, documentSection largeDocumentModule largeDocs typeAbbrev: Prot, hasProtocol: True, hasSap: False, hasIcf: False, label: Study Protocol, date: 2024-02-20, uploadDate: 2024-02-20T05:22, filename: Prot_000.pdf, size: 96217, largeDocs typeAbbrev: ICF, hasProtocol: False, hasSap: False, hasIcf: True, label: Informed Consent Form, date: 2024-02-20, uploadDate: 2024-02-20T05:30, filename: ICF_001.pdf, size: 77805, hasResults: False
protocolSection identificationModule nctId: NCT06282640, orgStudyIdInfo id: 567, briefTitle: Comparıson Of Electromyography Results Before And After Vıtamın D Treatment In Patıents Wıth Carpal Tunnel Syndrome, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-12-30, primaryCompletionDateStruct date: 2022-06-30, completionDateStruct date: 2022-08-30, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Dr. Ayşe Güç, class: OTHER_GOV, collaborators name: Kayseri City Hospital, descriptionModule briefSummary: Therefore, we aimed to evaluate the effectiveness of vitamin D replacement therapy on pain, electrophysiological parameters, ultrasonographic measurement results and functional status scales in CTS patients with low serum vitamin D levels., conditionsModule conditions: Carpal Tunnel Syndrome, conditions: Vitamin D Deficiency, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 87, type: ACTUAL, armsInterventionsModule interventions name: Vitamin D, outcomesModule primaryOutcomes measure: electrophysiological scale., secondaryOutcomes measure: monofilament test, otherOutcomes measure: Boston symptom severity scale, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Kayseri City Hospital, city: Kayseri, country: Turkey, geoPoint lat: 38.73222, lon: 35.48528, hasResults: False
protocolSection identificationModule nctId: NCT06282627, orgStudyIdInfo id: 10430012010023, briefTitle: The COVID HOME Study: Prospective Cohort Study of Non-hospitalised COVID-19 Patients, acronym: COVID-HOME, statusModule overallStatus: COMPLETED, startDateStruct date: 2020-03-20, primaryCompletionDateStruct date: 2022-07-30, completionDateStruct date: 2022-08-30, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: University Medical Center Groningen, class: OTHER, collaborators name: ZonMw: The Netherlands Organisation for Health Research and Development, descriptionModule briefSummary: Background. Guidelines on COVID-19 management are developed as we learn from this pandemic. However, most research has been done on hospitalised patients and the impact of the disease on non-hospitalised and their role in transmission are not yet well understood.The COVID HOME study conducts research among COVID-19 patients and their family members who were not hospitalised during acute disease, to guide patient care and inform public health guidelines for infection prevention and control in the community and household.Methods. An ongoing prospective longitudinal observational study of COVID-19 outpatients was established in March 2020 at the beginning of the COVID-19 pandemic in the Netherlands. Laboratory confirmed SARS-CoV-2 infected individuals of all ages that did not merit hospitalisation, and their household (HH) members, were enrolled after written informed consent. Enrolled participants were visited at home within 48 hours after initial diagnosis, and then weekly on days 7, 14 and 21 to obtain clinical data, a blood sample for biochemical parameters/cytokines and serological determination; and a nasopharyngeal/throat swab plus urine, stool and sperm or vaginal secretion (if consenting) to test for SARS-CoV-2 by RT-PCR (viral shedding) and for viral culturing. Weekly nasopharyngeal/throat swabs and stool samples, plus a blood sample on days 0 and 21 were also taken from HH members to determine whether and when they became infected. All participants were invited to continue follow-up at 3-, 6-, 12- and 18-months post-infection to assess long-term sequelae and immunological status., conditionsModule conditions: COVID-19, conditions: Post-COVID-19 Syndrome, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 256, type: ACTUAL, armsInterventionsModule interventions name: Observational study, outcomesModule primaryOutcomes measure: SARS-CoV-2 infection, secondaryOutcomes measure: Long-term sequelae, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University Medical Center Groningen, city: Groningen, zip: 9713 GZ, country: Netherlands, geoPoint lat: 53.21917, lon: 6.56667, hasResults: False
protocolSection identificationModule nctId: NCT06282601, orgStudyIdInfo id: GUIGOU - Defaye 2023, briefTitle: STUDY OF THE EFFECT OF RHYTHMIC AND NON-RHYTHMIC MUSICAL PRIMING ON THE SYNTAX CAPACITY OF PRESBYACOUSTIC OLDER ADULTS, acronym: AMORCAGE MUSIC, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2024-03, completionDateStruct date: 2024-03, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Centre Hospitalier Universitaire Dijon, class: OTHER, descriptionModule briefSummary: Presbyacusis, or age-related hearing loss, is a public health problem, affecting 20% of men and 30% of women over the age of 70 according to the WHO. In the most incapacitating cases, hearing aids are required. Numerous studies have evaluated the benefits of hearing aids, particularly in terms of improved hearing and quality of life.However, the specific effect of music on language skills has not yet been studied in hearing-impaired older adults.In this context, it was decided to study the effect of musical priming on the syntactic abilities of adults aged 70 or older with presbyacusis.This study is based on the hypothesis that music priming with regular music optimizes the syntax language skills of people with presbyacusis, as has already been proven in adults and normal-hearing children., conditionsModule conditions: Presbyacousie, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 27, type: ESTIMATED, armsInterventionsModule interventions name: Audiogram, interventions name: Musical priming for the syntax test, interventions name: Test MMSE, interventions name: Barcelona Music Reward Questionnaire, outcomesModule primaryOutcomes measure: linguistic performance test focusing on syntax., eligibilityModule sex: ALL, minimumAge: 70 Years, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06282562, orgStudyIdInfo id: NL84223.018.23, briefTitle: FeelFit: High-intensity Interval Training to Improve Self-reported Physical Fitness in Brain Tumor Patients, acronym: FeelFit, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2026-08-15, completionDateStruct date: 2026-08-15, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Amsterdam UMC, location VUmc, class: OTHER, descriptionModule briefSummary: The FeelFit study aims to assess the effectiveness of High-Intensity Interval Training (HIIT) in improving self-reported physical fitness in adult brain tumor patients during periods of stable disease, as compared to a waiting-list control group. Furthermore, several secondary and exploratory outcomes will be evaluated. The study is part of the GRIP (GuaRding quality survivorshiP) project, which aims to improve quality of life in brain tumor patients., conditionsModule conditions: Brain Tumor, Primary, conditions: Exercise, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 36, type: ESTIMATED, armsInterventionsModule interventions name: High-Intensity Interval Training (HIIT), outcomesModule primaryOutcomes measure: Self-reported physical fitness, secondaryOutcomes measure: Self-reported fitness, secondaryOutcomes measure: VO2max, otherOutcomes measure: Daily physical activity, otherOutcomes measure: Health-related quality of life questionnaire, otherOutcomes measure: Perceived functional impairments, otherOutcomes measure: Self-efficacy, otherOutcomes measure: Mastery, otherOutcomes measure: Brain tumor specific quality of life questionnaire, otherOutcomes measure: Subjective Happiness, otherOutcomes measure: Subjective cognitive functioning, otherOutcomes measure: Subjective cognitive failure, otherOutcomes measure: Fatigue questionnaire, otherOutcomes measure: Sleep questionnaire, otherOutcomes measure: Anxiety questionnaire, otherOutcomes measure: Self-reported depression questionnaire, otherOutcomes measure: Depression questionnaire, otherOutcomes measure: Muscle strength, otherOutcomes measure: Subjective physical fitness, otherOutcomes measure: Objective neurocognitive functioning, otherOutcomes measure: Objective neurological functioning, otherOutcomes measure: Brain imaging (optional), otherOutcomes measure: Brain activity (optional), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: VU University Medical Centers, location VUmc, status: RECRUITING, city: Amsterdam, zip: 1081 HV, country: Netherlands, contacts name: Marieke Blom, Msc, role: CONTACT, phone: +31621522442, email: gripopfitheid@amsterdamumc.nl, geoPoint lat: 52.37403, lon: 4.88969, hasResults: False