protocolSection identificationModule nctId: NCT06273761, orgStudyIdInfo id: UW 23-550, briefTitle: Evaluation of Medication Management Service, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-06, primaryCompletionDateStruct date: 2026-08-01, completionDateStruct date: 2027-05-01, studyFirstPostDateStruct date: 2024-02-23, lastUpdatePostDateStruct date: 2024-02-23, sponsorCollaboratorsModule leadSponsor name: The University of Hong Kong, class: OTHER, collaborators name: Hong Kong Jockey Club Charities Trust, collaborators name: Hong Kong Sheng Kung Hui Welfare Council, collaborators name: Hong Kong Young Women's Christian Association, collaborators name: Haven of Hope Hospital, collaborators name: Pok Oi Hospital, collaborators name: St. James Settlement, collaborators name: Aberdeen Kai-fong Welfare Association, collaborators name: Health In Action, collaborators name: Lok Sin Tong Benevolent Society, Kowloon, descriptionModule briefSummary: Medication management services (MMS) is a pharmacist-led service of optimizing the medication use and health outcomes, by promoting medication safety and enhancing the ability in self-management of health and diseases of patients and their caregivers. Yet, only limited evidence on the implementation of MMS service in Hong Kong is available. The goal of this clinical trial is to evaluate the cost effectiveness and effects of implementing MMS in community pharmacies owned by 8 non-government organizations (NGOs) in Hong Kong on humanistic and clinical outcomes in patients with hypertension and/or type II diabetes mellitus. The clinical trial aims to look into the following aspects:* To evaluate the perception and satisfaction of patients on MMS service* To investigate whether MMS could improve patients' adherence to their medication regimen, health-related quality of life, health outcomes and health service utilization, as well as their ability to understand and cope with their illness and drug-related problems* To identify and categorize the types of drug-related problems identified during MMS* To evaluate the cost-effectiveness of implementing MMS in community pharmaciesMMS services will be rolled out in a total of 8 NGO community pharmacies progressively (2 pharmacies per phase) in 4 successive phases. Participants will complete the questionnaires at the following time points throughout the trial, namely 1) during recruitment, 2) baseline (1 month before MMS), 3) 3 months after MMS begins, 4) 12 months after MMS begins, and 5) 24 months after MMS begins. Researchers will compare the results of questionnaires conducted at different time points to identify the potential changes in the effects of MMS. Furthermore, researchers will link up the electronic health records of the participants and identify the potential changes in the health outcomes and health service utilizations after receiving MMS., conditionsModule conditions: Medication Adherence, conditions: Medication Safety, conditions: Diabetes Mellitus, Type 2, conditions: Hypertension, conditions: Polypharmacy, conditions: High Risk Medications, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 640, type: ESTIMATED, armsInterventionsModule interventions name: Medication Management Service (MMS), outcomesModule primaryOutcomes measure: Medication adherence, secondaryOutcomes measure: Additional health service utilization, secondaryOutcomes measure: Patient perception and satisfaction, secondaryOutcomes measure: Patient perceived sensitivity to medicines, secondaryOutcomes measure: Social impact, secondaryOutcomes measure: Health-related quality of life, secondaryOutcomes measure: Drug-related problems, secondaryOutcomes measure: Change in costs, secondaryOutcomes measure: Change in effectiveness, secondaryOutcomes measure: Incremental cost effectiveness ratio (ICER), secondaryOutcomes measure: Beliefs in medicines, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Aberdeen Kai-Fong Welfare Association A-Lively Community Pharmacy, status: RECRUITING, city: Hong Kong, country: Hong Kong, contacts name: Kam Kit Mak, role: CONTACT, phone: 3550 5460, email: kennethmak.kk@aka.org.hk, geoPoint lat: 22.27832, lon: 114.17469, locations facility: Health In Action Community Pharmacy, status: RECRUITING, city: Hong Kong, country: Hong Kong, contacts name: Ka Shing Mak, role: CONTACT, phone: 3612 9515, email: simonmak@hia.org.hk, geoPoint lat: 22.27832, lon: 114.17469, locations facility: Hong Kong Sheng Kung Hui Welfare Council Community Pharmacy, status: RECRUITING, city: Hong Kong, country: Hong Kong, contacts name: Sze Yin Lee, role: CONTACT, phone: 2116 0382, email: wtspharm@skhwc.org.hk, geoPoint lat: 22.27832, lon: 114.17469, locations facility: PHARM+ Haven of Hope Community Pharmacy, status: RECRUITING, city: Hong Kong, country: Hong Kong, contacts name: Mei Lun Bruce Tsui, role: CONTACT, phone: 2156 2280, email: compharm@hohcs.org.hk, geoPoint lat: 22.27832, lon: 114.17469, locations facility: PHARM+ Pok Oi Hospital Community Pharmacy, status: RECRUITING, city: Hong Kong, country: Hong Kong, contacts name: Kwok leung Li, role: CONTACT, phone: 59506880, email: ylcppharm1@pokoi.org.hk, contacts name: Anson Tsz Kin Leung, role: CONTACT, email: ylcppharic@pokoi.org.hk, geoPoint lat: 22.27832, lon: 114.17469, locations facility: PHARM+ St. James' Settlement Community Pharmacy, status: RECRUITING, city: Hong Kong, country: Hong Kong, contacts name: Kit Sze Chan, role: CONTACT, phone: 2835 4320, email: ks.chan@sjs.org.hk, geoPoint lat: 22.27832, lon: 114.17469, locations facility: PHARM+ The Lok Sin Tong Community Pharmacy, status: RECRUITING, city: Hong Kong, country: Hong Kong, contacts name: William Ho Ching Yuen, role: CONTACT, phone: 21872780, email: tpcp@loksintong.org, geoPoint lat: 22.27832, lon: 114.17469, locations facility: PHARM+ YWCA Community Pharmacy, status: RECRUITING, city: Hong Kong, country: Hong Kong, contacts name: Sui Hong Ho, role: CONTACT, phone: 2511 6020, email: jackyho@ywca.org.hk, geoPoint lat: 22.27832, lon: 114.17469, hasResults: False