hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06366542, orgStudyIdInfo id: 2/2024, briefTitle: Virtual Reality in People With Persistent Postural-Perceptual Dizziness: RCT, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-05-01, primaryCompletionDateStruct date: 2023-12-31, completionDateStruct date: 2024-03-01, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: University of Jordan, class: OTHER, descriptionModule briefSummary: This study aimed to compare the effectiveness of virtual reality (VR) and vestibular rehabilitation therapy (VRT) in enhancing balance in individuals with Persistent Postural-Perceptual Dizziness (PPPD). The experimental group received VR combined with VRT and optokinetic stimulation, while the control group received VRT and optokinetic stimulation. The study involved 42 individuals diagnosed with PPPD and administered ten intervention sessions over six weeks. The study also examined the impact of VR on various aspects of PPPD, including dizziness, visual vertigo, mental well-being, sleep quality, fall risk, and overall quality of life., conditionsModule conditions: Vestibular Dizziness, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 42, type: ACTUAL, armsInterventionsModule interventions name: Vestibular rehabilitation therapy, interventions name: Virtual reality exercises, interventions name: Optokinetic Stimulation exercises, outcomesModule primaryOutcomes measure: The Niigata Persistent Postural-Perceptual Dizziness Questionnaire (NPQ), primaryOutcomes measure: The Niigata Persistent Postural-Perceptual Dizziness Questionnaire (NPQ), primaryOutcomes measure: The Niigata Persistent Postural-Perceptual Dizziness Questionnaire (NPQ), primaryOutcomes measure: Dizziness Handicap Inventory (DHI), primaryOutcomes measure: Dizziness Handicap Inventory (DHI), primaryOutcomes measure: Falls Efficacy Scale International (FES-I), primaryOutcomes measure: Falls Efficacy Scale International (FES-I), primaryOutcomes measure: Dynamic Gait Index (DGI), primaryOutcomes measure: Dynamic Gait Index (DGI), secondaryOutcomes measure: Pittsburgh Sleep Quality Index (PSQI), secondaryOutcomes measure: Pittsburgh Sleep Quality Index (PSQI), secondaryOutcomes measure: Hospital Anxiety and Depression Scale (HADS), secondaryOutcomes measure: Hospital Anxiety and Depression Scale (HADS), secondaryOutcomes measure: Medical Outcomes Study Short Form 12 (SF-12), secondaryOutcomes measure: Medical Outcomes Study Short Form 12 (SF-12), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Royal Medical Services, city: Amman, country: Jordan, geoPoint lat: 31.95522, lon: 35.94503, hasResults: False
protocolSection identificationModule nctId: NCT06366516, orgStudyIdInfo id: FUOBGY2024-23, briefTitle: Role of Methylation Test Triage in HPV Positive Women, acronym: MTTRIHPW, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-08, completionDateStruct date: 2026-02, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Obstetrics & Gynecology Hospital of Fudan University, class: OTHER, collaborators name: Peking Union Medical College Hospital, collaborators name: Chengdu Women's and Children's Central Hospital, collaborators name: Guangdong Women and Children Hospital, collaborators name: Second Hospital of Jilin University, collaborators name: First Affiliated Hospital of Xinjiang Medical University, collaborators name: Third Affiliated Hospital of Zhengzhou University, descriptionModule briefSummary: The pathological results were used as the gold standard in this study and the investigators analyze the diagnostic value of six gene methylation status (ASTN1 DLX1, ITGA4, RXFP3, SOX17, ZNF671) in triaging high-risk human papillomavirus infection. The sensitivity and specificity of methylation test and cytology in the diagnosis of high-grade cervical lesions are compared in order to providing new methods and basis in improving the accuracy of cervical cancer screening., conditionsModule conditions: Precancerous Cervical Lesion, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: Women who aged 25 to 65 years are screened for cervical cancer and they are all positive of high-risk HPV., primaryPurpose: SCREENING, maskingInfo masking: NONE, enrollmentInfo count: 10000, type: ESTIMATED, armsInterventionsModule interventions name: Methylation Test, outcomesModule primaryOutcomes measure: The sensitivity and specificity of methylation test in detecting CIN2+., secondaryOutcomes measure: KAPPA value of methylation test., eligibilityModule sex: FEMALE, minimumAge: 25 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Obstetrics and Gynecology Hospital of Fudan University, city: Shanghai, state: Shanghai, zip: 200011, country: China, contacts name: Long Sui, Professor, role: CONTACT, phone: 0086-021-33189900, email: suilong@fudan.edu.cn, contacts name: Qing Cong, PHD, role: CONTACT, phone: 0086-021-33189900, email: qingcong@fudan.edu.cn, geoPoint lat: 31.22222, lon: 121.45806, hasResults: False
protocolSection identificationModule nctId: NCT06366503, orgStudyIdInfo id: RS-2023-05, briefTitle: Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-10-03, primaryCompletionDateStruct date: 2023-12-29, completionDateStruct date: 2023-12-29, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Revision Skincare, class: INDUSTRY, descriptionModule briefSummary: This randomized, single-center, double-blinded, split-face, controlled clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after fractional ablative CO2 laser treatment and for 14 days post-procedure with three times daily application in healthy female subjects aged 35 to 65 with moderate to severe global facial overall photodamage (score of 4 to 9 out of the 10-point Modified Griffiths' scale). Furthermore, this clinical trial compared the active post-procedure cream to a comparator anhydrous formulation often paired with skin rejuvenation procedures. This is a cosmetic study with a FDA-regulated device.A total of 22 healthy female subjects completed the study., conditionsModule conditions: Photoaging, conditions: Wrinkle, conditions: Skin Laxity, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized, Single-Center, Double-Blinded, Split-Face, Controlled, primaryPurpose: OTHER, maskingInfo masking: DOUBLE, maskingDescription: Subjects were randomly assigned to use the active post-procedure cream on one side of the face and the comparator anhydrous formulation on the opposite side of the face.The products were packaged in the same container and labelled post-procedure cream. This was a double blinded study, where the investigator, study subject, and other study personnel involved in the evaluation of the efficacy or safety were blinded to group during the study., whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 23, type: ACTUAL, armsInterventionsModule interventions name: Fractional Ablative CO2 Laser, interventions name: Facial Cleanser, interventions name: Facial Moisturizer, interventions name: Sunscreen, interventions name: Basic Ointment, outcomesModule primaryOutcomes measure: Investigator Tolerability, primaryOutcomes measure: Incidence of Adverse Events, primaryOutcomes measure: Subject Tolerability, secondaryOutcomes measure: Self-Assessment Questionnaire, eligibilityModule sex: FEMALE, minimumAge: 35 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The Dermatology Group, city: Blue Ash, state: Ohio, zip: 45242, country: United States, geoPoint lat: 39.232, lon: -84.37827, hasResults: False
protocolSection identificationModule nctId: NCT06366490, orgStudyIdInfo id: CIP2023-001, briefTitle: Safety and Immunogenicity of Innocell Autologous Cellular Immunotherapy in Recurrent Epithelial Ovarian Cancer, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2024-12-01, completionDateStruct date: 2025-03-01, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: PhotonPharma, Inc., class: INDUSTRY, descriptionModule briefSummary: Safety and Immunogenicity of InnocellTM Autologous Cellular Immunotherapy Administered in Patients with Recurrent Epithelial Ovarian Cancer, conditionsModule conditions: Ovarian Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: The study is a 2-part design. For each participant, Part 1 will involve tissue procurement and confirmation of the ability to manufacture the Innocell vaccine, followed by Part 2 which is the treatment phase, involving Innocell administration to patients., primaryPurpose: TREATMENT, maskingInfo masking: NONE, maskingDescription: Open label Phase I trial with no masking, enrollmentInfo count: 8, type: ESTIMATED, armsInterventionsModule interventions name: Innocell Autologous Cellular Immunotherapy, outcomesModule primaryOutcomes measure: Saferty and Immunogenicity of Innocell in Ovarian Cancer Patients, primaryOutcomes measure: Safety of Innocell in Ovarian Cancer Patients, primaryOutcomes measure: Immunogenicity of Innocell in Ovarian Cancer Patients, primaryOutcomes measure: Immunogemicity in Ovarian Cancer Patients, primaryOutcomes measure: Immunogenicity of Innocell Vaccine in Ovarian Cancer Patients, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06366477, orgStudyIdInfo id: B-ER-103-417, briefTitle: Effects of Vibration Stimulation Combined With Task-oriented Training on Hand Motor Function in Chronic Stroke, statusModule overallStatus: COMPLETED, startDateStruct date: 2017-01-01, primaryCompletionDateStruct date: 2019-06-15, completionDateStruct date: 2019-11-15, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: National Cheng-Kung University Hospital, class: OTHER, descriptionModule briefSummary: There is a lack of effective therapies for hand and finger function recovery in people with chronic stroke. This study assessed the effects of combining vibration stimulation with task-oriented training on functional recovery, and treatment persistence. Participants with chronic stroke underwent 24 sessions of vibration stimulation combined with task-oriented training over 12 weeks, in addition to regular therapy. Functional recovery was assessed using the Fugl-Meyer assessment for motor function (FMA-wrist and hand), the Box and Blocks Test (BBT) for hand dexterity, and the Motor Activity Log (MAL) for daily functional activities. Minimal detectable change (MDC) and minimal important difference (MID) criteria were applied to interpret changes in assessment scores., conditionsModule conditions: Rehabilitation, conditions: Stroke, conditions: Hand Grasp, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 3, type: ACTUAL, armsInterventionsModule interventions name: Vibration stimulation combined with task-oriented training, outcomesModule primaryOutcomes measure: Fugl-Meyer assessment - wrist and hand, primaryOutcomes measure: Box and Blocks Test, primaryOutcomes measure: Motor Activity Log, primaryOutcomes measure: Quantitative Electroencephalography Analysis: Delta Brain Symmetry Index, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06366425, orgStudyIdInfo id: RECHMPL23_0272, briefTitle: Screening for Chronic Liver Diseases in General Population, acronym: HEPGEN, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2024-05-01, completionDateStruct date: 2025-03, studyFirstPostDateStruct date: 2024-04-15, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: University Hospital, Montpellier, class: OTHER, collaborators name: On-call medical home (MMG) Clermont-Hérault, descriptionModule briefSummary: Improving the care of patients with liver diseases in primary care and will allow patients with chronic liver disease to benefit from a course appropriate care., conditionsModule conditions: Fibrosis, Liver, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 260, type: ESTIMATED, armsInterventionsModule interventions name: Blood sample then fibroscan, outcomesModule primaryOutcomes measure: Evaluation of the liver fibrosis screening acceptability (FIB-4), primaryOutcomes measure: Evaluation of the liver fibrosis screening acceptability (FIB-4 and Fibroscan), secondaryOutcomes measure: Prevalence of advanced liver fibrosis by elastometry pulse (Fibroscan®) with a FIB-4 score>2.67, secondaryOutcomes measure: Prevalence of excessive consumption of alcohol, secondaryOutcomes measure: Prevalence of a history or drug use, secondaryOutcomes measure: The correlation between advanced liver fibrosis and risk factors for liver disease (presence of metabolic syndromes, viral hepatitis, alcool use disorders), secondaryOutcomes measure: prevalence of viral hepatitis, secondaryOutcomes measure: Description of socio-demographic characteristics of participants, eligibilityModule sex: ALL, minimumAge: 40 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: CHU de Montpellier, city: Montpellier, zip: 34295, country: France, contacts name: Magdalena MESZAROS, MD, role: CONTACT, phone: : 04 67 33 02 57, email: m-meszaros@chu-montpellier.fr, contacts name: Magdalena MESZAROS, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 43.61092, lon: 3.87723, hasResults: False
protocolSection identificationModule nctId: NCT06366412, orgStudyIdInfo id: serum Tau-217 in elderly, briefTitle: Dexmedetomidine on Postoperative Cognitive Dysfunction and Serum Tau-217 Protein., statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-03, completionDateStruct date: 2026-03, studyFirstPostDateStruct date: 2024-04-15, lastUpdatePostDateStruct date: 2024-04-15, sponsorCollaboratorsModule leadSponsor name: Minia University Hospital, class: OTHER, descriptionModule briefSummary: To assess the effect of Dexmedetomidine on serum Tau-217 protein and its relation to the incidence and severity of postoperative cognitive dysfunction in elderly patients undergoing major surgery under general anesthesia., conditionsModule conditions: Cognitive Impairment, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SCREENING, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 94, type: ESTIMATED, armsInterventionsModule interventions name: Dexmedetomidine Hydrochloride, interventions name: normal saline, outcomesModule primaryOutcomes measure: the effect of dexmedetomidine on serum Tau-217 protein value., secondaryOutcomes measure: to evaluate the postoperative cognitive dysfunction using Mini-Mental State Scale in both the placebo and dexmedetomidine group., otherOutcomes measure: Heart Rate changes in the intraoperative period after induction of anesthesia and every 10 minutes till the end of surgery and postoperative period after 1 hour and every hour till 6 hours postoperative then every 6 hours, otherOutcomes measure: Mean Arterial Blood Pressure changes in the intraoperative period after induction of anesthesia and every 10 minutes till the end of surgery and postoperative period after 1 hour and every hour till 6 hours postoperative then every 6 hours, eligibilityModule sex: ALL, minimumAge: 65 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Arwa Essam, status: RECRUITING, city: Minya, zip: 61111, country: Egypt, contacts name: Arwa essam Essam, assistant lecturer, role: CONTACT, phone: +201017565658, email: arwty26@gmail.com, geoPoint lat: 28.10988, lon: 30.7503, hasResults: False
protocolSection identificationModule nctId: NCT06366399, orgStudyIdInfo id: 00156659, briefTitle: The Acute T-Rex (Timing of Resistance Exercise) Study, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-11-15, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-04-15, lastUpdatePostDateStruct date: 2024-04-15, sponsorCollaboratorsModule leadSponsor name: University of Utah, class: OTHER, descriptionModule briefSummary: The primary aim of this study is to evaluate if a single bout of AM vs PM resistance exercise has different effects on insulin sensitivity and sleep. A randomized cross-over trial be used to compare resistance exercise at two different times of the day. Each condition will take place in a laboratory setting. Each condition will consist of exercise, overnight sleep, and oral glucose tolerance tests the following day. The AM exercise will occur \~1.5 hours after habitual wake, and PM exercise will occur \~11 hours after habitual wake. After a 2-6 week washout, participants will complete the other condition. The hypothesis is that PM exercise will be more beneficial than AM exercise in improving insulin sensitivity. This study could identify if there is a better time of day to perform resistance exercise to decrease risk of developing Type 2 Diabetes Mellitus., conditionsModule conditions: Diabetes Mellitus, Type 2, conditions: Insulin Resistance, conditions: Glucose Intolerance, conditions: Sleep Disturbance, conditions: Overweight or Obesity, conditions: Insulin Sensitivity, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: PREVENTION, maskingInfo masking: DOUBLE, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: Resistance Exercise Timing, outcomesModule primaryOutcomes measure: Insulin sensitivity, secondaryOutcomes measure: Sleep Duration, otherOutcomes measure: Sleep Staging, otherOutcomes measure: Sleep Quality, otherOutcomes measure: Sleep Efficiency, otherOutcomes measure: Muscular Strength, otherOutcomes measure: Perceived Hunger, otherOutcomes measure: Perceived Fullness, otherOutcomes measure: Perceived Prospective Food Consumption, otherOutcomes measure: Glucose Area Under Curve, otherOutcomes measure: Insulin Area Under Curve, eligibilityModule sex: ALL, minimumAge: 50 Years, maximumAge: 74 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Utah HPER E Buildling, status: RECRUITING, city: Salt Lake City, state: Utah, zip: 84112, country: United States, contacts name: Jason V Thomas, MS, role: CONTACT, email: jason.v.thomas@utah.edu, contacts name: Tanya M Halliday, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 40.76078, lon: -111.89105, hasResults: False
protocolSection identificationModule nctId: NCT06366373, orgStudyIdInfo id: 531118232022, briefTitle: An Evaluation on a Mental Health Art Exhibition's Impact on Reducing Stigma, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-02, completionDateStruct date: 2025-02, studyFirstPostDateStruct date: 2024-04-15, lastUpdatePostDateStruct date: 2024-04-15, sponsorCollaboratorsModule leadSponsor name: Hunan University, class: OTHER, collaborators name: Central South University, descriptionModule briefSummary: Mental health art exhibitions, as an intervention strategy integrating artistic expression and social contact, have the potential to positively impact the elimination of stigma and discrimination associated with mental health problems. This study will utilize a real-world quasi-randomized controlled trial design and a 6-month follow-up questionnaire survey to evaluate the intervention's impact on stigma/discrimination and related outcomes, such as mental health literacy. The evaluation will encompass four categories of people: those with lived experience of mental disorders, family members and friends of those with lived experience, health professionals, and the general public. Additionally, the cost-effectiveness of the art exhibition intervention will be analyzed., conditionsModule conditions: Mental Health Issue, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The interventional study model for this clinical trial is a quasi-randomized controlled trial design. The intervention is the exhibition, organized by "Qixi Charity," will publicly display offline artworks reflecting the diverse dimensions of mental health and ill-health. In contrast, the control group in this study will receive either printed or online educational materials, serving as a more traditional educational intervention. The study will include a baseline survey before the interventions (T0), a follow-up survey in the first month after the interventions (T1), and a follow-up survey in the sixth month after the interventions (T2) in both the experimental group (those who attend the offline exhibition) and the control group (those who are unable to attend the exhibition but will be provided with printed/online education materials)., primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 1200, type: ESTIMATED, armsInterventionsModule interventions name: A mental health art exhibition, interventions name: printed or online education materials, outcomesModule primaryOutcomes measure: Stigma/discrimination regarding mental disorders, secondaryOutcomes measure: mental health literacy, otherOutcomes measure: intervention costs, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False