hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06313060, orgStudyIdInfo id: 010, briefTitle: Efficacy of Carbonated Beverages in the Resolution of Alimentary Esophageal Impaction, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-15, primaryCompletionDateStruct date: 2025-01-01, completionDateStruct date: 2027-01-01, studyFirstPostDateStruct date: 2024-03-15, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: Hospital del Río Hortega, class: OTHER, descriptionModule briefSummary: Objectives: To evaluate the efficacy of the administration of carbonated beverages in the resolution of dietary esophageal impaction, and to identify subgroups in which their effectiveness may be different: patients with/without esophageal diseases, with/without a history of impaction.Methods: A clinical trial was conducted randomizing consecutive patients with a clinical diagnosis of dietary esophageal impaction to receive 200cc of carbonated drink or not at all, excluding patients with a previous diagnosis of non-esophageal stenosis that could not be overcome with a gastroscope and suspected impaction by non-alimentary foreign bodies, spines or bones. Subsequently, an endoscopic evaluation will be carried out in all cases, checking the presence or absence of a foreign body and removing it if necessary, as well as assessing and recording the possible underlying esophageal pathology.A telephone follow-up will be carried out after 7 days, recording possible adverse events., conditionsModule conditions: Esophagus Disorder, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized clinical trial, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: INVESTIGATOR, enrollmentInfo count: 354, type: ESTIMATED, armsInterventionsModule interventions name: Coca-cola, outcomesModule primaryOutcomes measure: Efficacy of carbonated beverage for disimpaction, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06313047, orgStudyIdInfo id: Doxorubacin in HCC, briefTitle: Pharmacogenetic of Doxorubicin in HCC., statusModule overallStatus: COMPLETED, startDateStruct date: 2021-01-01, primaryCompletionDateStruct date: 2023-12-15, completionDateStruct date: 2023-12-30, studyFirstPostDateStruct date: 2024-03-15, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Rehab Werida, class: OTHER, collaborators name: King Saud Bin Abdulaziz University for Health Sciences, collaborators name: King Abdullah Bin Abdulaziz University Hospital, descriptionModule briefSummary: The study included 81 HCC patients, both male and female. Prior to being assessed for eligibility, each recruited patient with HCC received a comprehensive review of their medical history, physical status, and laboratory results. Every research participant take part in the experiment and provided written informed consent., conditionsModule conditions: Hepatocellular Carcinoma, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 81, type: ACTUAL, armsInterventionsModule interventions name: Doxorubicin, outcomesModule primaryOutcomes measure: GSTP1, primaryOutcomes measure: CYP2B6, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: King Abdullah bin Abdulaziz University Hospital, city: Riyadh, country: Saudi Arabia, geoPoint lat: 24.68773, lon: 46.72185, hasResults: False
protocolSection identificationModule nctId: NCT06313034, orgStudyIdInfo id: GU-SBF-OPA-02, briefTitle: The Effect of Breastfeeding Training Given to Mothers With Vaginal Birth by Motivational Interview Technique, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-05-01, primaryCompletionDateStruct date: 2024-03-15, completionDateStruct date: 2024-03-15, studyFirstPostDateStruct date: 2024-03-15, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: Gümüşhane Universıty, class: OTHER, collaborators name: Karadeniz Technical University, descriptionModule briefSummary: This study aimed to determine the effect of breastfeeding education given to mothers who gave birth vaginally using motivational interviewing technique on breastfeeding motivation, self-efficacy and attachment. The study will be conducted as a single-blind, randomized controlled trial., conditionsModule conditions: Breastfeeding, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The sample of the research will consist of mothers who gave primary vaginal birth (40 experimental group and 40 control group), primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: SINGLE, maskingDescription: While it is known by the researcher whether the mothers are in the experimental or control group, it is not known by the mother., whoMasked: PARTICIPANT, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Breastfeeding education based on motivational interviewing technique, outcomesModule primaryOutcomes measure: Mother Introductory Information Form, primaryOutcomes measure: Primipara Breastfeeding Motivation Scale, primaryOutcomes measure: Breastfeeding Self-Efficacy Scale Short Form, primaryOutcomes measure: Mother-Baby Attachment Scale, eligibilityModule sex: FEMALE, minimumAge: 20 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Gümüşhane University, status: RECRUITING, city: Gümüşhane, country: Turkey, contacts name: ÖZGE PALANCI AY, role: CONTACT, geoPoint lat: 40.46001, lon: 39.47176, hasResults: False
protocolSection identificationModule nctId: NCT06313008, orgStudyIdInfo id: EMBA-VILDA-Response trial., briefTitle: Empagliflozin Versus Vildagliptin in CAD Patients With T2DM, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-08-10, primaryCompletionDateStruct date: 2024-06-01, completionDateStruct date: 2024-06-10, studyFirstPostDateStruct date: 2024-03-15, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Damanhour University, class: OTHER, collaborators name: Tanta University, descriptionModule briefSummary: We compared the cardioprotective effects of empagliflozin, an SGLT2 inhibitor, with those of vildagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, focusing on various inflammatory biomarkers lipid profile, and cardiac function, in patients with type 2 diabetes mellitus (T2DM)., conditionsModule conditions: Coronary Artery Disease, conditions: Type 2 Diabetes, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: This was a prospective, randomized, double-dummy, blinded-endpoint, parallel-group trial that enrolled 120 CAD patients with T2DM. The patients were randomized 1: 1 for 6 months administration of empagliflozin or vildagliptin., primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: Empagliflozin 10 MG, interventions name: Vildagliptin 50 MG, outcomesModule primaryOutcomes measure: LVEF %, primaryOutcomes measure: Sortilin (ng/ml), primaryOutcomes measure: LDL (mg/dl), secondaryOutcomes measure: hsCRP (mg/L), secondaryOutcomes measure: HbA1c %, secondaryOutcomes measure: FBG (mg/dl), eligibilityModule sex: ALL, minimumAge: 40 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Rehab Hussein Werida, status: RECRUITING, city: Damanhūr, state: Elbehairah, zip: 31527, country: Egypt, contacts name: Naglaa Khedr, Prof., role: CONTACT, email: naglaa.khedr@pharm.tanta.edu.eg, contacts name: Lamiaa Khedr, Ass.Prof., role: CONTACT, email: lamiaa_khedr@yahoo.com, geoPoint lat: 31.03408, lon: 30.46823, hasResults: False
protocolSection identificationModule nctId: NCT06312995, orgStudyIdInfo id: T3DDY02, briefTitle: Investigation of a Medical Device for the Immobilisation of Radius and Ulna Fractures in Paediatric Patients, acronym: T3DDY02, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-03-14, primaryCompletionDateStruct date: 2025-02-14, completionDateStruct date: 2025-06-14, studyFirstPostDateStruct date: 2024-03-15, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: Meyer Children's Hospital IRCCS, class: OTHER, descriptionModule briefSummary: Single-centre, randomised, controlled, non-profit study on a custom-made medical device for immobilisation of radius and ulna fracture in paediatric patients.The aim of the study is to evaluate the benefits in terms of comfort, safety and efficacy resulting from the use of a customised 3D-printed wrist immobilisation device in children aged between 7 and 13 with a fracture of the distal metaphysis of radius or ulna of the 'green stick' type, compared to a control group treated with traditional immobilisation devices. The patients will be randomised between use of customised 3D- printed wrist immobilisisation device and plaster., conditionsModule conditions: Fractures, Bone, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: T3DDY01, interventions name: PLASTER, outcomesModule primaryOutcomes measure: Fracture Healing, secondaryOutcomes measure: Adverse event, secondaryOutcomes measure: Comfort of use of devices, secondaryOutcomes measure: Presence of skin lesions or other manifestations of intolerance to the device, secondaryOutcomes measure: Pain evaluation, secondaryOutcomes measure: Acceptance of the device, secondaryOutcomes measure: Structural analysis of devices, secondaryOutcomes measure: Usability for design purposes of the controlate, eligibilityModule sex: ALL, minimumAge: 7 Years, maximumAge: 13 Years, stdAges: CHILD, contactsLocationsModule locations facility: Meyer Children's Hospital IRCCS, status: RECRUITING, city: Florence, zip: 50139, country: Italy, contacts name: Alessandro Zanardi, MD, role: CONTACT, phone: 055 5662908, email: alessadro.zanardi@meyer.it, geoPoint lat: 43.77925, lon: 11.24626, hasResults: False
protocolSection identificationModule nctId: NCT06312956, orgStudyIdInfo id: 21C403, briefTitle: Multidimensional Evaluation of Patients' Affected by Obstructive Apnea Syndrome (OSAS) Before and After Ventilotherapy, acronym: MULTI-OSAS, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-29, primaryCompletionDateStruct date: 2025-06, completionDateStruct date: 2026-02, studyFirstPostDateStruct date: 2024-03-15, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: Istituto Auxologico Italiano, class: OTHER, descriptionModule briefSummary: This observational study aims to evaluate multiple dimensions of health in patients with Obstructive Sleep Apnea Syndrome (OSAS), before and after three weeks of ventilotherapy.Specifically, the study aims to identify pre- vs post-treatment differences in the following domains:* cognitive performance* blood expression of biomarkers related to neurodegeneration* psychosocial wellbeingThus, patients will complete the following evaluations before (T0) and after (T1) ventilotherapy:* neuropsychological standard assessment* blood sampling* psychosocial self-reported questionnaires, conditionsModule conditions: Obstructive Sleep Apnea, conditions: Sleep Disorder, conditions: Well-Being, Psychological, conditions: Cognitive Impairment, conditions: Cognitive Change, conditions: Neurologic Signs, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 65, type: ESTIMATED, armsInterventionsModule interventions name: Continuous Positive Airway Pressure Ventilotherapy, outcomesModule primaryOutcomes measure: Overall cognitive functioning, primaryOutcomes measure: Selective attention, primaryOutcomes measure: Memory and learning, primaryOutcomes measure: Visuo-spatial abilities, primaryOutcomes measure: Inhibition, primaryOutcomes measure: Planning, primaryOutcomes measure: Decision making, secondaryOutcomes measure: biomarkers of neurodegeneration, secondaryOutcomes measure: psychosocial wellbeing and satisfaction, secondaryOutcomes measure: Quality of life (perceived psycho-physical and socio-economic wellbeing and satisfaction), eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: IRCCS Istituto Auxologico Italiano, status: RECRUITING, city: Piancavallo, state: VCO, zip: 28824, country: Italy, contacts name: Sofia Tagini, PhD, role: CONTACT, phone: 00393339915288, email: s.tagini@auxologico.it, hasResults: False
protocolSection identificationModule nctId: NCT06312930, orgStudyIdInfo id: HSEARS20220816001-03, briefTitle: Transcranial Pulse Stimulation on Motor Cortex, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-20, primaryCompletionDateStruct date: 2024-08-20, completionDateStruct date: 2024-08-20, studyFirstPostDateStruct date: 2024-03-15, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: The Hong Kong Polytechnic University, class: OTHER, descriptionModule briefSummary: Transcranial pulse stimulation (TPS) is a newly developed non-invasive brain stimulation (NIBS) technique from Austria \& Germany with highly promising applicability in neuropsychiatric disorders. Clinical trials have shown a beneficial effect of TPS in patients with Alzheimer's disease and depression. However, the mechanism of action of TPS treatment is unknown. There is a lack of controlled studies with sufficient sample size to draw reliable conclusions on the modulatory effect of TPS. The primary motor cortex is a common target when investigating the neuromodulation effect of NIBS techniques. Here, a randomized, cross-over, double-blind, sham-controlled clinical trial is proposed to probe the effects of TPS over the primary motor cortex on modulating motor response and motor behavior., conditionsModule conditions: Healthy Adults, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Transcranial pulse stimulation, outcomesModule primaryOutcomes measure: Change in movement time in nine-hole peg test after TPS, primaryOutcomes measure: Change in reaction time in Deary-Liewald reaction time task after TPS, secondaryOutcomes measure: The influence of motor excitability measured by resting motor threshold (RMT) on post-TPS task performance measured by nine-hole peg test and Deary-Liewald reaction time task, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Georg Kranz, PhD, city: Hong Kong, country: Hong Kong, contacts name: Georg Kranz, PhD, role: CONTACT, phone: 27664838, email: georg.kranz@polyu.edu.hk, contacts name: Georg S. Kranz, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 22.27832, lon: 114.17469, hasResults: False
protocolSection identificationModule nctId: NCT06312917, orgStudyIdInfo id: 2023PHB183, briefTitle: Effect of Physical Activity Intervention on Overweight and Obese Patients With Endometrial Cancer, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-06-01, primaryCompletionDateStruct date: 2023-12-30, completionDateStruct date: 2024-02-01, studyFirstPostDateStruct date: 2024-03-15, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: Peking University People's Hospital, class: OTHER, descriptionModule briefSummary: This study evaluated the clinical outcome of exercise management on patients with endometrial cancer treated with fertility preservation, including the effect of complete response rate, complete response time, recurrence rate, recurrence time, etc., and physical composition, to evaluate the effectiveness of physical activity on weight management., conditionsModule conditions: Endometrium Cancer, conditions: Physical Activity, conditions: Weight Management, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 72, type: ACTUAL, armsInterventionsModule interventions name: Physical activity, outcomesModule primaryOutcomes measure: Body weight, primaryOutcomes measure: BMI, primaryOutcomes measure: physical activity level, secondaryOutcomes measure: serum total cholesterol, secondaryOutcomes measure: Waist Hip Ratio, secondaryOutcomes measure: triglyceride, eligibilityModule sex: FEMALE, minimumAge: 20 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Peking University People's Hospital, city: Beijing, state: Beijing, country: China, geoPoint lat: 39.9075, lon: 116.39723, hasResults: False
protocolSection identificationModule nctId: NCT06312904, orgStudyIdInfo id: 2023-GSP-QN-7, briefTitle: Paravertebral Block for Postoperative Analgesia in Children Undergoing Lateral Incision Cardiac Surgery With CBP, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-11, primaryCompletionDateStruct date: 2024-11-30, completionDateStruct date: 2024-12-30, studyFirstPostDateStruct date: 2024-03-15, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: Chinese Academy of Medical Sciences, Fuwai Hospital, class: OTHER, descriptionModule briefSummary: This study aims to compare the effect of paravertebral block and local infiltration anesthesia on postoperative analgesia in children undergoing lateral incision cardiac surgery with cardiopulmonary bypass. The researchers hope to investigate whether children who undergo paravertebral block experience less postoperative pain, have fewer postoperative complications, and recover more quickly., conditionsModule conditions: Postoperative Pain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: paravertebral block, interventions name: Local infiltration anesthesia, outcomesModule primaryOutcomes measure: opioid consumption during the first 24h after surgery, secondaryOutcomes measure: FPS-R scale recorded at 6, 12, 18 and 24h postoperatively, secondaryOutcomes measure: The rate of opioid treatment for remedial analgesia between groups, otherOutcomes measure: Length of postoperative mechanical ventilation, otherOutcomes measure: Length of ICU/hospital stay, otherOutcomes measure: The incidence of respiratory depression, otherOutcomes measure: The rate of postoperative nausea and vomiting (PONV) during the 24h postoperatively, eligibilityModule sex: ALL, minimumAge: 6 Years, maximumAge: 14 Years, stdAges: CHILD, contactsLocationsModule, documentSection largeDocumentModule largeDocs typeAbbrev: Prot_SAP_ICF, hasProtocol: True, hasSap: True, hasIcf: True, label: Study Protocol, Statistical Analysis Plan, and Informed Consent Form, date: 2024-02-26, uploadDate: 2024-03-08T09:29, filename: Prot_SAP_ICF_000.pdf, size: 294106, hasResults: False
protocolSection identificationModule nctId: NCT06312891, orgStudyIdInfo id: VOHRLTIAM, briefTitle: Value of Heart Rate Lowering Therapy in Acute Myocarditis, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-04-01, completionDateStruct date: 2025-06-01, studyFirstPostDateStruct date: 2024-03-15, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: To study the value of heart rate lowering therapy "pharmacological rest" on the short term in cases of myocarditis without LV dysfunction., conditionsModule conditions: Myocarditis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 150, type: ESTIMATED, armsInterventionsModule interventions name: Ivabradine, outcomesModule primaryOutcomes measure: Value of Heart Rate Lowering Therapy in Acute Myocarditis, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 90 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Heart Hospital, status: RECRUITING, city: Assiut, country: Egypt, contacts name: sara mahmoud, master, role: CONTACT, phone: 01016862195, email: saramahmoud199783@gmail.com, geoPoint lat: 27.18096, lon: 31.18368, hasResults: False