hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06319157, orgStudyIdInfo id: SYSKY-2023-1263-02, briefTitle: Minimal Access Versus Conventional Latissimus Dorsi Flap Harvest for Breast Reconstruction, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2028-11, completionDateStruct date: 2028-11, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, class: OTHER, descriptionModule briefSummary: For patients refusing implants for breast reconstruction after cancer surgery, autologous tissue flap reconstruction using the latissimus dorsi muscle is an alternative. Conventional surgery leaves a long incision on the back, affecting aesthetics and quality of life. Minimal access techniques result in a smaller, more concealable scar. While previous studies suggest its safety and effectiveness, most are retrospective. To further validate patient satisfaction and short-term outcomes, a prospective, randomized controlled trial comparing minimal access with conventional surgery is planned. The primary endpoint is Breast Q-satisfaction with back score at 6 months. Secondary outcomes include other Breast Q subscales, surgical metrics, and complications. The study aims to enroll 94 patients in total, providing evidence for surgical decision-making in breast cancer reconstruction., conditionsModule conditions: Breast Neoplasms, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 94, type: ESTIMATED, armsInterventionsModule interventions name: minimal access breast reconstruction with a latissimus dorsi muscle flap, interventions name: conventional breast reconstruction with a latissimus dorsi muscle flap, outcomesModule primaryOutcomes measure: Breast Q-satisfaction with back, secondaryOutcomes measure: Patient satisfaction, secondaryOutcomes measure: Latissimus dorsi acquisition time, secondaryOutcomes measure: Intraoperative blood loss, secondaryOutcomes measure: Postoperative pain, secondaryOutcomes measure: Postoperative complications, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Sun Yat-sen Memorial Hospital, Sun Yat-sen University, status: RECRUITING, city: Guangzhou, state: Guangdong, zip: 510120, country: China, contacts name: Shicheng Su, M.D., Ph.D., role: CONTACT, phone: +86 13632394954, email: lnl_trial@126.com, contacts name: Erwei Song, M.D., Ph.D., role: CONTACT, phone: +86 13719237746, email: lnl_trial@126.com, geoPoint lat: 23.11667, lon: 113.25, hasResults: False
protocolSection identificationModule nctId: NCT06319144, orgStudyIdInfo id: KYLL20240306-1, briefTitle: Effect of Intravenous 5% Dextrose Infusion During Recovery From Anesthesia on the Quality of Early Postoperative Recovery in Patients Undergoing Painless Gastrointestinal Endoscopy, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-14, primaryCompletionDateStruct date: 2024-03-14, completionDateStruct date: 2024-05-05, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Weifang Medical University, class: OTHER, descriptionModule briefSummary: The aim of this study was to determine the effect of intravenous infusion of 5% dextrose injection during the recovery period of anesthesia for painless gastroenteroscopy on the patient's blood glucose level, incidence of hypoglycemia and time of awakening from anesthesia, postoperative vertigo, postoperative nausea and vomiting, and quality of recovery in the early postoperative period., conditionsModule conditions: Insulin Resistance, conditions: Postoperative Nausea and Vomiting, conditions: Quality of Recovery, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: 5% glucose, interventions name: 0.9% Normal Saline, outcomesModule primaryOutcomes measure: Preoperative blood glucose 30min, primaryOutcomes measure: Postoperative blood glucose 30min, primaryOutcomes measure: Postoperative nausea and vomiting, primaryOutcomes measure: Postoperative nausea and vomiting, primaryOutcomes measure: Postoperative nausea and vomiting, primaryOutcomes measure: Postoperative nausea and vomiting, secondaryOutcomes measure: Anesthesia awakening time, secondaryOutcomes measure: Dizziness level, secondaryOutcomes measure: Dizziness level, secondaryOutcomes measure: Dizziness level, secondaryOutcomes measure: Quality of postoperative recovery (QoR40), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Lin Cheng, status: RECRUITING, city: Weifang, state: Shandong, zip: 261041, country: China, contacts name: Lin Cheng, B.S, role: CONTACT, phone: 17667404256, email: 1318216353@qq.com, geoPoint lat: 36.71, lon: 119.10194, hasResults: False
protocolSection identificationModule nctId: NCT06319131, orgStudyIdInfo id: Tipharosis, briefTitle: Nadroparin Versus TIPS in Cirrhotic Patients With Refractory Asymptomatic PVT, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2025-05-30, completionDateStruct date: 2026-05-30, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-21, sponsorCollaboratorsModule leadSponsor name: Shanghai Zhongshan Hospital, class: OTHER, collaborators name: Shanghai 6th People's Hospital, collaborators name: ShuGuang Hospital, collaborators name: Tongji Hospital, collaborators name: Renmin Hospital of Wuhan University, descriptionModule briefSummary: The purpose of this study is to evaluate the comparative effectiveness of nadroparin versus transjugular intrahepatic portosystemic shunt in cirrhotic patients with refractory asymptomatic portal vein thrombosis using a design of a multicenter, randomized controlled trial, conditionsModule conditions: Portal Vein Thrombosis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 84, type: ESTIMATED, armsInterventionsModule interventions name: TIPS, interventions name: Nadroparin, outcomesModule primaryOutcomes measure: complete recanalization rate of PVT, secondaryOutcomes measure: partial recanalization rate of PVT, secondaryOutcomes measure: Bleeding rate, secondaryOutcomes measure: Mortality, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06319118, orgStudyIdInfo id: JD-LK2023091-I01, briefTitle: A Clinical Study of Dihydroergotine Mesylate Extended-release Tablets for the Treatment of Drooling in Parkinson's Disease., statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-10-01, primaryCompletionDateStruct date: 2024-06-30, completionDateStruct date: 2024-12-30, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Second Affiliated Hospital of Soochow University, class: OTHER, descriptionModule briefSummary: Objective: To evaluate the efficacy and safety of dihydroergotine mesylate extended-release tablets for salivation in Parkinson\&#39;s disease Study content: Using a randomized, double-blind, placebo-controlled study design, 120 patients with Parkinson\&#39;s disease and cognitive impairment were enrolled, and the treatment was followed up for 12 weeks: dihydroergotine mesylate sustained-release tablets + conventional treatment (treatment group patients, 80 cases), placebo + conventional treatment (control group patients, 40 cases), and the main indicators were observed: the improvement effect of dihydroergotine mesylate sustained-release tablets on PD salivation was observed, and the secondary indicators were observed: the effect of dihydroergotine mesylate sustained-release tablets on the cognitive function of PD patients was observed.Expected results: The improvement effect of dihydroergotine mesylate sustained-release tablets on PD salivation was significantly different from that of the placebo control group. The dihydroergotine mesylate sustained-release tablet group had a significant effect on the cognitive function of PD patients., conditionsModule conditions: Salivation in Parkinson's Disease, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: Placebo, interventions name: dihydroergotine mesylate sustained-release tablets, outcomesModule primaryOutcomes measure: the objective weight of saliva in patients with Parkinson's disease changed from baseline, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The Second Arilliated Hospital of Soochow University, city: Suzhou, state: Jiangsu, zip: 215004, country: China, geoPoint lat: 31.30408, lon: 120.59538, hasResults: False
protocolSection identificationModule nctId: NCT06319092, orgStudyIdInfo id: 2023/175, briefTitle: Immersive Virtual Reality Version of the 6 Minute Pegboard and Ring Test, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-06-01, primaryCompletionDateStruct date: 2023-10-01, completionDateStruct date: 2023-12-01, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Gaziantep Islam Science and Technology University, class: OTHER, descriptionModule briefSummary: The 6 Minute Pegboard and Ring Test is a test applicable to the upper extremities. The upper extremity plays an important role in activities of daily living, especially in tasks related to reaching, grasping and holding objects. Various activities of daily living, such as combing hair, brushing teeth and picking up objects, require supported or unsupported upper limb activity. Therefore, evaluation of upper extremity function is important. In addition, it is a simple test, it is also seen as a game, its application is functional, and there is no need for expensive equipment. Its validity and reliability have been demonstrated only for patients with Chronic Obstructive Pulmonary Disease (COPD) and healthy adults. In addition, to the best of our knowledge, the suitability of this test in a virtual environment has not been evaluated in the literature. Therefore, the main aim of this study is to examine the applicability of this test in a virtual environment., conditionsModule conditions: Healthy, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 30, type: ACTUAL, outcomesModule primaryOutcomes measure: 6 Minute Pegboard and Ring Test, primaryOutcomes measure: Immersive virtual reality version of the 6 Minute Pegboard and Ring Test, secondaryOutcomes measure: Quick Shoulder-Hand Syndromes Questionnaire, secondaryOutcomes measure: Assessment of handgrip, secondaryOutcomes measure: 9 Hole Peg Test, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Gaziantep İslamic Science and Technology University, city: Gaziantep, state: Şahinbey, zip: 27000, country: Turkey, geoPoint lat: 37.05944, lon: 37.3825, hasResults: False
protocolSection identificationModule nctId: NCT06319066, orgStudyIdInfo id: RGNS65-152, briefTitle: Customized Foot Orthoses With Orthotic Wedges for Plantar Heel Pain, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-11-30, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Mahidol University, class: OTHER, descriptionModule briefSummary: The present study will use a randomized controlled trial (RCT) to determine the effectiveness of customized foot orthosis (CFO) for the treatment of patients with PHP. Three treatment groups including the CFO without wedge, the CFO with wedge type 1 (W1), and the CFO with wedge type 2 (W2) will be randomly assigned to each participant by a computer-generated randomization. The opaque-sealed envelopes will be used to allocate the groups of participant., conditionsModule conditions: Foot Orthoses, conditions: Fasciitis, Plantar, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: SINGLE_GROUP, interventionModelDescription: The present study will use a randomized controlled trial (RCT) to determine the effectiveness of CFO for the treatment of patients with PHP. Three treatment groups including the CFO without wedge, the CFO with W1, and the CFO with W2 will be randomly assigned to each participant by a computer-generated randomization. The opaque-sealed envelopes will be used to allocate the groups of participant., primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: Participants will be allocated to the control (CFO without wedge) or experimental (CFO with W1 or W2) groups according to the seal-envelop randomization technique. Then, they will be assessed all outcomes for the baseline including pain intensity, foot function, plantar fascia thickness, balance outcomes, and gait parameters by the 2nd physical therapist. And the participants will receive the assigned treatment by the 1st physical therapist., whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: orthotic wedge, interventions name: CFO, outcomesModule primaryOutcomes measure: Pain intensity and foot function, primaryOutcomes measure: Plantar Fascia Thickness, primaryOutcomes measure: Gait assessment, primaryOutcomes measure: Balance assessment, secondaryOutcomes measure: Low back and Lower-extremity pain, secondaryOutcomes measure: Transversus abdominis (TrA) Thickness, otherOutcomes measure: Subjective assessment, otherOutcomes measure: Physical assessment, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06319053, orgStudyIdInfo id: NL85402.078.23, briefTitle: The Turbine-based Insufflator Safety and Feasibility Study, acronym: TBI, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-04, primaryCompletionDateStruct date: 2024-09, completionDateStruct date: 2024-10, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Erasmus Medical Center, class: OTHER, collaborators name: Politecnico di Milano University, collaborators name: Health∼Holland, Topsector Life Sciences & Health, collaborators name: Spatium Medical B.V., collaborators name: IDE Group B.V., descriptionModule briefSummary: The turbine-based insufflator for minimal access surgery provides a new technological basis for minimal invasive surgery insufflation. Turbine technology permits highly accurate pressure control, an intra-abdominal volume that is dynamically adapted to ventilation, and oscillometric measurements of abdominal compliance. This first-in-human study aims to evaluate technologic feasibility in terms of pressure stability performance and the safety of the device., conditionsModule conditions: Laparoscopy, conditions: Pneumoperitoneum, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SEQUENTIAL, interventionModelDescription: Consecutive patients from who informed consent can be acquired. The number of twelve participants was determined in conjunction with the Ethical Board of Erasmus MC, primaryPurpose: DEVICE_FEASIBILITY, maskingInfo masking: NONE, enrollmentInfo count: 12, type: ESTIMATED, armsInterventionsModule interventions name: Turbine-based insufflator, outcomesModule primaryOutcomes measure: Occurrence of (serious) adverse device effects [Safety and feasibility of the device], secondaryOutcomes measure: Observation of insufflation pressure stability by continuously monitoring and recording., secondaryOutcomes measure: Gas volume exchange, secondaryOutcomes measure: Estimation of the abdominal compliance, secondaryOutcomes measure: Intra-abdominal target pressure in relation to the abdominal compliance, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Erasmus MC, University Medical Center Rotterdam, status: RECRUITING, city: Rotterdam, state: Zuid Holland, zip: 3015 GD, country: Netherlands, contacts name: J. Vlot, MD, PhD, role: CONTACT, phone: +31107039568, email: john.vlot@erasmusmc.nl, contacts name: A.I. de Jong, MD, role: CONTACT, phone: +31107037641, email: a.i.dejong@erasmusmc.nl, geoPoint lat: 51.9225, lon: 4.47917, hasResults: False
protocolSection identificationModule nctId: NCT06319040, orgStudyIdInfo id: MEDİPOL MEGA 1, briefTitle: The Effect Of Addıtıonal Surgery On Muscle Strength, Proprıoceptıon And Balance In Anterıor Crucıate Lıgament Surgery, statusModule overallStatus: COMPLETED, startDateStruct date: 2018-12-06, primaryCompletionDateStruct date: 2019-03-07, completionDateStruct date: 2019-06-07, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Medipol University, class: OTHER, descriptionModule briefSummary: Meniscal tears and RAMP lesions are frequently seen together with ACL injuries. The aim of this study was to evaluate the effects of meniscus repair and RAMP lesion repair ACL reconstruction surgery in terms of muscle strength, proprioception, and balance. In our study, the clinical outcomes of both anterior cruciate ligament reconstruction (ACLR), medial meniscus repair (MR) and RAMP lesion repair (RR) have been compared with those of isolated ACLR., conditionsModule conditions: Anterior Cruciate Ligament Injuries, conditions: Meniscus Lesion, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 45, type: ACTUAL, armsInterventionsModule interventions name: Muscle strength measurement, interventions name: Knee joint proprioception, interventions name: Balance, interventions name: Fall risk test, interventions name: Tegner Activity Level, interventions name: Lysholm Knee Scoring Scale, outcomesModule primaryOutcomes measure: muscle strength measurement, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Istanbul Medipol University, city: Istanbul, country: Turkey, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06319027, orgStudyIdInfo id: EAF223, secondaryIdInfos id: NCI-2023-08557, type: REGISTRY, domain: CTRP (Clinical Trial Reporting Program), secondaryIdInfos id: EAF223, type: OTHER, domain: ECOG-ACRIN Cancer Research Group, secondaryIdInfos id: EAF223, type: OTHER, domain: CTEP, secondaryIdInfos id: U10CA180820, type: NIH, link: https://reporter.nih.gov/quickSearch/U10CA180820, briefTitle: Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-12, primaryCompletionDateStruct date: 2027-05-31, completionDateStruct date: 2027-05-31, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: ECOG-ACRIN Cancer Research Group, class: NETWORK, descriptionModule briefSummary: This phase II trial studies whether different imaging techniques can provide additional and more accurate information than the usual approach for assessing the activity of tumors in patients with newly diagnosed glioblastoma. The usual approach for this currently is magnetic resonance imaging (MRI). This study is trying to learn more about the meaning of changes in MRI scans after treatment, as while the appearance of some of these changes may reflect progressing tumor, some may be due the treatment. Dynamic susceptibility contrast (DSC)-MRIs, along with positron emission tomography (PET) and/or magnetic resonance (MR) spectroscopy, may help doctors tell which changes are a reflection of the treatment and which changes may be due to progressing tumor., conditionsModule conditions: Glioblastoma, IDH-Wildtype, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging, interventions name: Fluciclovine F18, interventions name: Gadolinium-Chelate, interventions name: Magnetic Resonance Spectroscopy, interventions name: Positron Emission Tomography, outcomesModule primaryOutcomes measure: Overall survival (OS), primaryOutcomes measure: Event free survival (EFS), secondaryOutcomes measure: True disease progression and pseudo-progression (PsP), secondaryOutcomes measure: Progression-free survival (PFS), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False