hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06275880, orgStudyIdInfo id: F-2023-3201-066, briefTitle: Intraarticular Collagen in Patients With Gonarthrosis, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-04-01, primaryCompletionDateStruct date: 2023-07-30, completionDateStruct date: 2024-01-10, studyFirstPostDateStruct date: 2024-02-23, lastUpdatePostDateStruct date: 2024-02-23, sponsorCollaboratorsModule leadSponsor name: Instituto Mexicano del Seguro Social, class: OTHER_GOV, descriptionModule briefSummary: The objective of this clinical trial is to verify the effectiveness of polyvinyl pyrrolidone collagen in all patients with symptomatic gonarthrosis grades II-IV in patients over 40 years of age. The main objectives that this study aims to answer are the following:1. - Document the effectiveness of intra-articular polyvinylpyrrolidone collagen in the treatment of symptomatic gonarthrosis.2. - Compare the intensity of pain, the degree of stiffness and functionality of the joint, prior to application and one month after the therapeutic intervention.3. - Identify demographic, clinical and therapeutic factors that influence the effectiveness of intra-articular PVP collagen in the treatment of symptomatic gonarthrosis.Patients diagnosed with symptomatic gonarthrosis Grade II-IV, referred to the Physical Medicine and Rehabilitation service within 3 months, will be selected. Two study groups will be assigned: GROUP those who received intra-articular infiltration of PVP Collagen, GROUP B: patients who received conservative treatment. Through rehabilitation with a home program for one month, in both cases, ENA and the WOMAC scale will be evaluated at the beginning of the study and after 4 weeks., conditionsModule conditions: Gonarthrosis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 130, type: ACTUAL, armsInterventionsModule interventions name: Intra-articular infiltration of PVP Collagen, interventions name: Rehabilitation, outcomesModule primaryOutcomes measure: Western Ontario and McMaster Universities Osteoarthritis Index - Pain, primaryOutcomes measure: Western Ontario and McMaster Universities Osteoarthritis Index - stiffness, primaryOutcomes measure: Western Ontario and McMaster Universities Osteoarthritis Index - functionality, primaryOutcomes measure: Number Analog Scale for pain, eligibilityModule sex: ALL, minimumAge: 40 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hospital General Regional No. 1 Lic. Ignacio García Téllez, city: Mérida, state: Yucatán, zip: 97155, country: Mexico, geoPoint lat: 20.97537, lon: -89.61696, hasResults: False
protocolSection identificationModule nctId: NCT06275867, orgStudyIdInfo id: SOPRIMA//T023635, briefTitle: Improved Access to Quality Care and Healthcare Use, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-20, primaryCompletionDateStruct date: 2024-06-10, completionDateStruct date: 2024-08-30, studyFirstPostDateStruct date: 2024-02-23, lastUpdatePostDateStruct date: 2024-02-23, sponsorCollaboratorsModule leadSponsor name: London School of Economics and Political Science, class: OTHER, collaborators name: University of Witwatersrand, South Africa, descriptionModule briefSummary: This study is an individual-level randomised controlled trial which looks at the effect of providing free access to higher quality providers in urban South Africa. The study will recruit about 1,500 individuals with a child aged 5 or under. They will be randomly allocate to a control group (CONTROL) with the default free access to government facilities or one of the two treatment groups where they will have free access to private providers located either relatively close (CONVENIENT) by or relatively far (INCONVENIENT). The primary outcomes be overuse and underuse of healthcare services for children under 5, conditionsModule conditions: Health Care Utilization, conditions: Health Knowledge, Attitudes, Practice, conditions: Health, Subjective, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: SINGLE, whoMasked: CARE_PROVIDER, enrollmentInfo count: 1500, type: ESTIMATED, armsInterventionsModule interventions name: Free high-quality care, interventions name: Close distance, interventions name: Far distance, outcomesModule primaryOutcomes measure: Underuse, primaryOutcomes measure: Overuse, secondaryOutcomes measure: Illness duration, secondaryOutcomes measure: Out-of-pocket expenditures, secondaryOutcomes measure: Health knowledge, eligibilityModule sex: ALL, minimumAge: 2 Months, maximumAge: 6 Years, stdAges: CHILD, contactsLocationsModule locations facility: HDSS Soweto clusters, status: RECRUITING, city: Soweto, state: Gauteng, country: South Africa, contacts name: Nomalanga Boyce, role: CONTACT, email: nomalanga.boyce@wits-vida.org, geoPoint lat: -26.26781, lon: 27.85849, hasResults: False
protocolSection identificationModule nctId: NCT06275854, orgStudyIdInfo id: 22265, briefTitle: YASU Research Registry: For Young Adults With Cancer, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2030-05-01, completionDateStruct date: 2030-05-01, studyFirstPostDateStruct date: 2024-02-23, lastUpdatePostDateStruct date: 2024-02-23, sponsorCollaboratorsModule leadSponsor name: Young Adult Survivors United, class: OTHER, collaborators name: Staunton Farm Foundation, collaborators name: Elsie H. Hillman Foundation, descriptionModule briefSummary: The goal of this observational research registry is to learn about health, wellbeing, and needs of survivors of young adult cancer (diagnosed between the ages of 18 and 39). The main question\[s\] it aims to understand are:* What are the levels of depression, anxiety, social support, and financial distress* Determine effectiveness of YASU programming by measuring changes over timeWith this registry, the investigators also plan to identify survivors who may be eligible for participation in future research studies pertaining to young adult cancer.Participants will be asked to complete electronic surveys every 6 to 12 months during participation in the registry., conditionsModule conditions: Cancer, conditions: Leukemia, conditions: Sarcoma, conditions: Germ Cell Cancer, conditions: Lymphoma, conditions: Colorectal Cancer, conditions: Melanoma, conditions: Breast Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 5000, type: ESTIMATED, outcomesModule primaryOutcomes measure: Anxiety, primaryOutcomes measure: Depressive symptoms, primaryOutcomes measure: Social Support, primaryOutcomes measure: Financial Toxicity, primaryOutcomes measure: Needs Assessment, secondaryOutcomes measure: Name, address, email, phone number, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06275841, orgStudyIdInfo id: C4891035, briefTitle: A Study to Learn If the Study Medicine Esomeprazole Changes How the Body Processes the Other Study Medicine Vepdegestrant, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-23, primaryCompletionDateStruct date: 2024-05-03, completionDateStruct date: 2024-05-24, studyFirstPostDateStruct date: 2024-02-23, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Pfizer, class: INDUSTRY, collaborators name: Arvinas Estrogen Receptor, Inc., descriptionModule briefSummary: The purpose of the study is to investigate the effect of multiple doses of a proton-pump inhibitor (PPI) esomeprazole on the PK of vepdegestrant under fed conditions in healthy adult participants.All participants in this study will receive one dose of vepdegestrant alone by mouth in Period 1. In Period 2, everyone will receive esomeprazole by mouth once a day for multiple days. Participants will also receive one dose of vepdegestrant by mouth. The levels of vepdegestrant in Period 1 will be compared to the levels of vepdegestrant in Period 2 to determine if the PPI affects how vepdegestrant is processed differently in healthy adults., conditionsModule conditions: Healthy, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: CROSSOVER, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 12, type: ESTIMATED, armsInterventionsModule interventions name: vepdegestrant, interventions name: esomeprazole, outcomesModule primaryOutcomes measure: Maximum observed plasma concentration (Cmax) of vepdegestrant when vepdegestrant is administered alone, primaryOutcomes measure: Maxium observed plasma concentration of vepdegestrant when vepdegestrant is administered with esomeprazole, primaryOutcomes measure: Area under the curve from time zero to extrapolated infinite time (AUCinf) when vepdegestrant is administered alone, primaryOutcomes measure: Area under the curve from time zero to extrapolated infinite time (AUCinf) when vepdegestrant is administered with esomeprazole, secondaryOutcomes measure: number of participants with treatment-emergent adverse events (AEs) and serious adverse events (SAEs), secondaryOutcomes measure: Number of participants with clinical laboratory abnormalities, secondaryOutcomes measure: Number of participants with electrocardiogram (ECG) abnormalities, secondaryOutcomes measure: Number of participans with clinically significant change from baseline in vital signs, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Pfizer Clinical Research Unit - New Haven, status: RECRUITING, city: New Haven, state: Connecticut, zip: 06511, country: United States, geoPoint lat: 41.30815, lon: -72.92816, hasResults: False
protocolSection identificationModule nctId: NCT06275828, orgStudyIdInfo id: PoliceGeneralHospiral, briefTitle: The Effect of Perioperative and Postoperative Music Reduces Pain Perception After Anterior Cruciate Ligament Reconstruction, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2022-12-15, primaryCompletionDateStruct date: 2023-07-31, completionDateStruct date: 2024-02-20, studyFirstPostDateStruct date: 2024-02-23, lastUpdatePostDateStruct date: 2024-02-23, sponsorCollaboratorsModule leadSponsor name: Police General Hospital, Thailand, class: OTHER, descriptionModule briefSummary: study the effect of music therapy in pre-operative and post operative period and measure the out come by the visual analog scale (pain score) and analgesic drug use such as morphine and the anxiety score, conditionsModule conditions: Anterior Cruciate Ligament Tear, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: TRIPLE, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 46, type: ACTUAL, armsInterventionsModule interventions name: slow beat mesic listening by headphone, outcomesModule primaryOutcomes measure: visual analog scale, secondaryOutcomes measure: analgesic drug use, secondaryOutcomes measure: Amsterdam Preoperative Anxiety and Information Scale, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Police General Hospital, city: Bangkok, state: Pathuwam, zip: 10330, country: Thailand, geoPoint lat: 13.75398, lon: 100.50144, hasResults: False
protocolSection identificationModule nctId: NCT06275802, orgStudyIdInfo id: 22-5.1T/2, briefTitle: The Effect of Nutrition Education Interventions for Adolescents, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-06-06, primaryCompletionDateStruct date: 2023-12-30, completionDateStruct date: 2024-06-30, studyFirstPostDateStruct date: 2024-02-23, lastUpdatePostDateStruct date: 2024-02-23, sponsorCollaboratorsModule leadSponsor name: Ege University, class: OTHER, descriptionModule briefSummary: The aim of this study is to determine the effect of nutrition education on nutritional literacy, nutritional status, eating habits and eating behavior in high school students. The research will be conducted in six high schools, three of which are intervention schools and three of which are control schools It is planned that a total of 1000 students will be included in the study from the intervention school and 1000 students from the control school. At the beginning of the study (June 2022), an introductory form (sociodemographic characteristics, body image (Stunkart scale), dietary habits, knowledge about weight status) was applied to all students. Adolescent Nutrition Literacy Scale (ANLS), Instrument of Nutrition Literacy, Mediterranean Diet Quality Index (KID-MED), Eating Attitudes Test 26 (EAT-26), International Physical Activity Questionnaire Short Form (IPAQ) were applied, anthropometric measurements and three-day food consumption records were taken. During the study, nutrition initiatives consisting of 8 modules will be made to the intervention schools. Control schools will not be interfered with during this period.At the end of the study, the procedures applied at the beginning will be repeated., conditionsModule conditions: Nutrition, Healthy, conditions: Nutrition Disorders in Adolescence, conditions: Eating Habit, conditions: Eating Behavior, conditions: Body Image, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 1000, type: ESTIMATED, armsInterventionsModule interventions name: Nutrition Education, interventions name: nutritional status, eating habits, outcomesModule primaryOutcomes measure: nutrition literacy, primaryOutcomes measure: Mediterranean Diet Quality Index (KID-MED), primaryOutcomes measure: Eating Attitudes Test 26 (EAT-26), primaryOutcomes measure: weight and height measurement, primaryOutcomes measure: waist circumference measurement, primaryOutcomes measure: Food Consumption Record, primaryOutcomes measure: International Physical Activity Questionnaire (IPAQ- Short Form), eligibilityModule sex: ALL, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Menemen District Directorate of National Education, status: RECRUITING, city: İzmir, country: Turkey, contacts name: Sibel ÖZER, role: CONTACT, phone: (0232) 832 26 29, geoPoint lat: 38.41273, lon: 27.13838, hasResults: False
protocolSection identificationModule nctId: NCT06275789, orgStudyIdInfo id: 2023-268, briefTitle: Mix of Demineralized Freeze-Dried Bone Allograft and Deproteinized Bovine Bone Mineral: a Possible Solution for Alveolar Ridge Preservation?, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-26, primaryCompletionDateStruct date: 2025-06, completionDateStruct date: 2025-06, studyFirstPostDateStruct date: 2024-02-23, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Nova Southeastern University, class: OTHER, collaborators name: Geistlich Pharma AG, collaborators name: ZimVie, descriptionModule briefSummary: The purpose of the study is to compare a new grafting material for alveolar ridge preservation to a commonly used and well studied material. Alveolar ridge dimensions as well as histology will be compared., conditionsModule conditions: Alveolar Ridge Preservation, conditions: Dental Extraction, conditions: Bone Graft, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Alveolar ridge preservation, outcomesModule primaryOutcomes measure: changes in horizontal dimensions of the alveolar ridge, primaryOutcomes measure: changes in vertical dimensions of the alveolar ridge, secondaryOutcomes measure: vital bone percentage, otherOutcomes measure: thickness of the buccal plate in mm and its influence on the ridge dimension, otherOutcomes measure: the thickness of the lingual plate in mm and its influence on the ridge dimension, otherOutcomes measure: the thickness of the overlying buccal soft tissue in mm and its influence on the ridge dimension, otherOutcomes measure: the position of extraction site (maxilla vs. mandible) and its influence on the ridge dimension, otherOutcomes measure: # of cigarettes and its influence on the ridge dimension, otherOutcomes measure: oral hygiene using the plaque index and its influence on the ridge dimension, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Nova Southeastern University, status: RECRUITING, city: Fort Lauderdale, state: Florida, zip: 33328, country: United States, contacts name: Saynur Vardar-Sengul, DDS, PhD, role: CONTACT, phone: 954-262-1815, email: svardarsengul@nova.edu, geoPoint lat: 26.12231, lon: -80.14338, hasResults: False
protocolSection identificationModule nctId: NCT06275750, orgStudyIdInfo id: CEI 175/23, briefTitle: Non-surgical Spinal Decompression in Patients With Chronic Low Back Pain, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-08-21, primaryCompletionDateStruct date: 2023-11-29, completionDateStruct date: 2024-01-11, studyFirstPostDateStruct date: 2024-02-23, lastUpdatePostDateStruct date: 2024-02-23, sponsorCollaboratorsModule leadSponsor name: Hospital Civil de Guadalajara, class: OTHER, descriptionModule briefSummary: The goal of this quasi-experimental trial was to evaluate the effects of non-surgical spinal decompression on disability and pain in patients with chronic low back pain and sciatica throughout a two-month follow-up, and to analyze the relationship between demographic factors and clinical outcomes after a program of non-surgical spinal decompression.The main questions it aims to answer were:* Non-surgical spinal decompression is effective to reduce pain intensity and self-reported disability in patients with chronic low back pain and sciatica?* Age, level of education and work activities are related with clinical outcome in patients treated with non-surgical spinal decompression?Participants underwent eight sessions, three per week, with the BTL-6000 spinal decompression system. The study did not have a comparison group., conditionsModule conditions: Low Back Pain, conditions: Sciatica, conditions: Lumbar Disc Herniation, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 39, type: ACTUAL, armsInterventionsModule interventions name: Spinal decompression with BTL-6000 spinal decompression system (BTL Industries Ltd.), outcomesModule primaryOutcomes measure: Self-reported disability, primaryOutcomes measure: Pain intensity, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule locations facility: Hospital Civil de Guadalajara Fray Antonio Alcalde, city: Guadalajara, state: Jalisco, zip: 44280, country: Mexico, geoPoint lat: 20.66682, lon: -103.39182, hasResults: False
protocolSection identificationModule nctId: NCT06275737, orgStudyIdInfo id: POP-UP G-128, briefTitle: POP-UP: a Single-arm, Two-cohort Study: Trimodal Prehab for Upper GI and Pancreatic Cancer, acronym: POP-UP, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2027-03, completionDateStruct date: 2027-03, studyFirstPostDateStruct date: 2024-02-23, lastUpdatePostDateStruct date: 2024-02-23, sponsorCollaboratorsModule leadSponsor name: GERCOR - Multidisciplinary Oncology Cooperative Group, class: OTHER, descriptionModule briefSummary: This is a multicenter, two-cohort, open-label, single-arm feasibility study. The primary objective is to assess the feasibility of the 8-week trimodal prehabilitation program alongside perioperative triplet chemotherapy in eligible patients with localized pancreatic ductal adenocarcinoma (PDAC) or oesogastric cancer (OGC) ., conditionsModule conditions: Pancreatic Ductal Adenocarcinoma, conditions: Esophageal Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: Two-cohort, open-label, single-arm feasibility study, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 72, type: ESTIMATED, armsInterventionsModule interventions name: Prehabilitation program, outcomesModule primaryOutcomes measure: Rate of patients with successful completion of an 8-week trimodal prehabilitation program, secondaryOutcomes measure: Success rate (as defined above) for Adapted Physical Activity (APA), nutritional, and psychological interventions measured separately., secondaryOutcomes measure: Health-related quality of life (HRQoL) assessment, secondaryOutcomes measure: Rate of patients who start and complete post-habilitation Adapted Physical Activity (APA) sessions, secondaryOutcomes measure: Nutritional status assessment, secondaryOutcomes measure: Physical/functional test assessment, secondaryOutcomes measure: Number of patients with reduced chemotherapy tolerance, secondaryOutcomes measure: Number of patients with chemotherapy dose modification, secondaryOutcomes measure: Rate of patients who complete the strategy, secondaryOutcomes measure: Number of patients with Granulocyte-colony stimulating factor (G-CSF) prescription and grade ≥ 2 neutropenia, secondaryOutcomes measure: Rate of patients with exocrine pancreatic insufficiency and the dose of pancreatic enzyme consumption, secondaryOutcomes measure: Rate of surgical complications, secondaryOutcomes measure: Overall survival (OS) assessment, secondaryOutcomes measure: Disease-free survival (DFS) assessment, secondaryOutcomes measure: Adherence to Adapted Physical Activity (APA) program assessment, secondaryOutcomes measure: Physical activity behavior changes assessment, secondaryOutcomes measure: Nurse coordination, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False