hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06287372, orgStudyIdInfo id: 3261, briefTitle: Comparison of Changes in Intra-myocardial Amino Acids During Use of Calafiore and Modified Del Nido Cardioplegia, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-07-04, primaryCompletionDateStruct date: 2023-07-04, completionDateStruct date: 2023-07-04, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-07, sponsorCollaboratorsModule leadSponsor name: Damascus University, class: OTHER, descriptionModule briefSummary: The aim of the present study was to investigate intra-operative changes in markers of myocardial injury and myocardial intracellular amino acids during ischemia and reperfusion, comparing two methods of myocardial protection; Calafiore intermittent antegrade warm blood cardioplegia or modified del Nido intermittent antegrade cold blood cardioplegia in routine coronary artery bypass grafting procedures., conditionsModule conditions: Myocardial Injury, conditions: Cardiac Surgery, conditions: Myocardial Protection, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 20, type: ACTUAL, armsInterventionsModule interventions name: Cardioplegic solution, outcomesModule primaryOutcomes measure: Changes in markers of myocardial injury, secondaryOutcomes measure: Changes in myocardial amino acid concentrations, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Damascus University Cardiac Surgery Hospital, city: Damascus, country: Syrian Arab Republic, geoPoint lat: 33.5102, lon: 36.29128, hasResults: False
protocolSection identificationModule nctId: NCT06287359, orgStudyIdInfo id: Local/2024/MP-01, briefTitle: Experience of Parents/Carers of Children With Severe Motor Disabilities Suffering From Spinal Pain?, acronym: Vé-Quo-Pa-H-R, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Centre Hospitalier Universitaire de Nīmes, class: OTHER, descriptionModule briefSummary: Parents of disabled children suffer from back pain more frequently than the general population. At present, the literature does not identify any specific factors responsible for this suffering.For patients suffering from chronic back pain, there are specific treatment programmes in the Physical Medicine and Rehabilitation Department, with a focus on pain management.The investigators would like to develop specific programmes for parents/carers of children/adolescents with severe motor disabilities.To achieve this, it is important to gain a better understanding of the factors that contribute to the onset of pain.With this in mind, the investigators are conducting a qualitative study to gain a better understanding of the day-to-day lives of these parents., conditionsModule conditions: Low Back Pain, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 15, type: ESTIMATED, armsInterventionsModule interventions name: individual interviews, outcomesModule primaryOutcomes measure: Individual interviews, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06287346, orgStudyIdInfo id: 240101, briefTitle: 5-Years PMCF Study of Ceramic Dental Implants One-piece Versus Two-piece., acronym: 240101, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2029-01-01, completionDateStruct date: 2030-01-01, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: CeraRoot SL, class: INDUSTRY, descriptionModule briefSummary: The goal of this cohort observational study is to compare in the survival rate of ceramic dental implants placed in patients with missing or hopeless teeth . The main question\[s\] it aims to answer are:* Are there any significant differences in survival rate between the use of one-piece ceramic implant versus the two-piece (TL) variant?* What are the complications associated to the procedure and differences between the two groups., conditionsModule conditions: Edentulism, conditions: Tooth Loss, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 652, type: ESTIMATED, armsInterventionsModule interventions name: dental implant, outcomesModule primaryOutcomes measure: Survival rate, secondaryOutcomes measure: Complications, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Family Holistic Dentistry, status: RECRUITING, city: Boulder, state: Colorado, zip: 80303, country: United States, contacts name: CARMEN BURKE, DDS, role: CONTACT, phone: 303-219-0499, email: carmen@carmenburke.com, contacts name: CARMEN BURKE, DDS, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 40.01499, lon: -105.27055, locations facility: CeraRoot CLINIC, status: RECRUITING, city: Les Franqueses del Vallès, state: Barcelona, zip: 08520, country: Spain, contacts name: JOSEP OLIVA-OCHOA, DDS MSC, role: CONTACT, phone: 800-485-1613, email: josep.oliva@cerarootclinic.com, contacts name: Ekaterina Treatment coordinator, role: CONTACT, phone: +34 935 950 247, email: ekaterina@ceraroot.com, contacts name: JOSEP OLIVA-OCHOA, DDS MSC, role: PRINCIPAL_INVESTIGATOR, contacts name: XAVIER OLIVA-OCHOA, DDS MSC, role: SUB_INVESTIGATOR, contacts name: CARLA OLIVA-PORTA, STUDENT, role: SUB_INVESTIGATOR, contacts name: ARNAU OLIVA-PORTA, STUDENT, role: SUB_INVESTIGATOR, geoPoint lat: 41.61929, lon: 2.29829, hasResults: False
protocolSection identificationModule nctId: NCT06287333, orgStudyIdInfo id: 2023PI221, briefTitle: Video-respiratory Polygraphy in Children, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-02-22, primaryCompletionDateStruct date: 2024-02-22, completionDateStruct date: 2024-02-28, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Central Hospital, Nancy, France, class: OTHER, descriptionModule briefSummary: The diagnosis of obstructive sleep apnea-hypopnea syndrome in children (OSAS) requires a polysomnography (PSG) in a sleep lab with video surveillance and monitoring by a nurse. But PSG is a cumbersome exam, sometimes difficult to perform in children. Simplified exams as respiratory polygraphy (RP) which uses only respiratory signals can be used for the diagnosis of OSAS but studies show that it underestimates the obstructive apnea-hypopnea index (OAHI) because the total sleep time cannot be accurately estimated. The use of a video camera with software synchronous with the RP software could compensate for this disadvantage, by estimating when the child is sleeping or not., conditionsModule conditions: Sleep Apnea, Obstructive, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 66, type: ESTIMATED, armsInterventionsModule interventions name: Polysomnography in routine care, outcomesModule primaryOutcomes measure: OAHI in video-RP significantly correlated with OAHI in PSG, secondaryOutcomes measure: Diagnostic ability of video-RP to identify OSAS in children, secondaryOutcomes measure: Diagnostic ability of video-RP to identify moderate-severe OSAS in children, eligibilityModule sex: ALL, minimumAge: 2 Years, maximumAge: 19 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06287320, orgStudyIdInfo id: Bioplc, briefTitle: The Predictive Biomarkers in Patients With Locally Advanced Non-small Cell Lung Cancer, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2025-12-31, completionDateStruct date: 2026-02-28, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Cancer Institute and Hospital, Chinese Academy of Medical Sciences, class: OTHER, descriptionModule briefSummary: This study is a prospective cohort study to evaluate the peripheral blood lymphocyte subsets as predicative biomarkers reflecting the efficacy and toxicity in patients with locally advanced non-small cell lung cancer (NSCLC) received chemoradiotherapy (CRT) with or without immune checkpoint inhibitors (ICIs)., conditionsModule conditions: Locally Advanced Non-small Cell Lung Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: concurrent or sequential chemoradiotherapy, interventions name: Immunotherapy, outcomesModule primaryOutcomes measure: Adverse Event, secondaryOutcomes measure: Progression-free survival (PFS), secondaryOutcomes measure: Overall survival (OS), secondaryOutcomes measure: Objective Response Rate (ORR), secondaryOutcomes measure: Disease control rate (DCR), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Chinese Academy of Medical Science and Peking Union Medical College, status: RECRUITING, city: Beijing, state: Beijing, zip: 100021, country: China, contacts name: Nan Bi, MD, PhD, role: CONTACT, email: binan_email@163.com, geoPoint lat: 39.9075, lon: 116.39723, hasResults: False
protocolSection identificationModule nctId: NCT06287294, orgStudyIdInfo id: RS23-042, briefTitle: An Investigation Into Taste Problems Associated With Xerostomia in Patients With Advanced Cancer, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-08-30, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Our Lady's Hospice and Care Services, class: OTHER, descriptionModule briefSummary: Taste problems and xerostomia (dry mouth) are common among patients with advanced cancer. These symptoms can affect the pleasure of eating and drinking, reduce dietary intake, cause low mood, and a lower quality of life. This study will explore the relationship between dry mouth and taste problems in patients with advanced cancer., conditionsModule conditions: Taste, Altered, conditions: Xerostomia, conditions: Neoplasms, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 120, type: ESTIMATED, outcomesModule primaryOutcomes measure: To measure the prevalence of taste problems in patients with advanced cancer with a dry mouth using the Oral Symptom Assessment Scale (questionnaire), primaryOutcomes measure: To identify an association of any other oral symptoms present in patients with taste problems and dry mouth who have advanced cancer using the Oral Symptom Assessment Scale (questionnaire), primaryOutcomes measure: To characterise the taste disturbances i.e. to identify reduced taste, heightened taste, altered taste or no taste using the Taste Questionnaire in Palliative Care (questionnaire) and Waterless Empirical Taste Test (objective taste test), primaryOutcomes measure: To identify what impact taste problems are having on patients dietary intake using the Taste Questionnaire in Palliative Care (questionnaire)., primaryOutcomes measure: To identify what impact taste problems are having on patients quality of life using the Taste Questionnaire in Palliative Care (questionnaire)., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Our Lady's Hospice and Care Services, status: RECRUITING, city: Dublin, zip: D6WRY72, country: Ireland, contacts name: Andrew Davies, FRCP, role: CONTACT, phone: 0035314986235, email: andavies@tcd.ie, contacts name: Marie Hannon, BSc, role: CONTACT, phone: 0035314912558, email: marie.hannon@ucdconnect.ie, geoPoint lat: 53.33306, lon: -6.24889, hasResults: False
protocolSection identificationModule nctId: NCT06287268, orgStudyIdInfo id: CETB115G1401, briefTitle: Revolade Tablets Specified Drug-use Survey, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-30, primaryCompletionDateStruct date: 2028-10-31, completionDateStruct date: 2028-10-31, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Novartis Pharmaceuticals, class: INDUSTRY, descriptionModule briefSummary: This is a multicenter, single-arm, non-interventional study (NIS) to confirm the safety and efficacy of eltrombopag in Anti-Thymocyte Globulin (ATG) treatment naive pediatric patients with aplastic anemia (AA)., conditionsModule conditions: Aplastic Anemia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: OTHER, enrollmentInfo count: 10, type: ESTIMATED, armsInterventionsModule interventions name: eltrombopag, outcomesModule primaryOutcomes measure: Occurrence of serious adverse events, secondaryOutcomes measure: Occurrence of adverse events and adverse drug reactions leading to treatment discontinuation, secondaryOutcomes measure: Occurrence of adverse events and adverse drug reactions applicable to safety specifications (hepatic dysfunction and hematopoietic malignancies), secondaryOutcomes measure: Occurrence of clonal evolution, secondaryOutcomes measure: Hematologic response status, secondaryOutcomes measure: Change over time from baseline in platelet count, secondaryOutcomes measure: Change over time from baseline in hemoglobin, secondaryOutcomes measure: Change over time from baseline in neutrophil count, secondaryOutcomes measure: Change over time from baseline in reticulocyte count, secondaryOutcomes measure: Change over time from baseline in transfusion dependence, secondaryOutcomes measure: Change over time from baseline in transfusion volume, eligibilityModule sex: ALL, minimumAge: 6 Years, maximumAge: 17 Years, stdAges: CHILD, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06287229, orgStudyIdInfo id: 2023-0627, secondaryIdInfos id: NCI-2024-01756, type: OTHER, domain: NCI-CTRP Clinical Registry, briefTitle: Phase Ib/II Study Assessing the Clinical Activity and Safety of Brexucabtagene Autoleucel as a Consolidation in Patients With Relapsed/Refractory (R/R) and Newly Diagnosed B-cell Acute Lymphocytic Leukemia (ALL) Post Cytoreduction With Mini-HCVD-inotuzumab-blinatumomab/HCVAD-inotuzumab-blinatumomab, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-08-31, primaryCompletionDateStruct date: 2028-12-31, completionDateStruct date: 2030-12-31, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-04-12, sponsorCollaboratorsModule leadSponsor name: M.D. Anderson Cancer Center, class: OTHER, descriptionModule briefSummary: To learn about the safety of giving the drug brexucabtagene autoleucel to participants with relapsed/refractory B-cell ALL after treatment with inotuzumab ozogamicin, blinatumomab, and either hyper-CVAD or mini-hyper-CVD. Also, to learn if giving brexucabtagene autoleucel to patients with relapsed/refractory or high-risk, newly diagnosed B-cell ALL after treatment with inotuzumab ozogamicin, blinatumomab, and either hyper-CVAD or mini-hyper-CVD can help to control the disease., conditionsModule conditions: Relapsed/Refractory, conditions: B-cell Acute Lymphocytic Leukemia, designModule studyType: INTERVENTIONAL, phases: PHASE1, phases: PHASE2, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Blinatumomab, interventions name: Inotuzumab Ozogamicin, interventions name: Hyper-CVAD, interventions name: Mini-hyper-CVD, outcomesModule primaryOutcomes measure: Safety and adverse events (AEs), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: MD Anderson Cancer Center, city: Houston, state: Texas, zip: 77030, country: United States, contacts name: Elias Jabbour, MD, role: CONTACT, phone: 713-792-4764, email: ejabbour@mdanderson.org, contacts name: Elias Jabbour, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 29.76328, lon: -95.36327, hasResults: False
protocolSection identificationModule nctId: NCT06287216, orgStudyIdInfo id: 2024001, briefTitle: Preliminary Evaluation of a Mental Health Program: a Comparison Study, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-02-29, primaryCompletionDateStruct date: 2024-04-30, completionDateStruct date: 2024-04-30, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: The Royal Ottawa Mental Health Centre, class: OTHER, descriptionModule briefSummary: The mental hygiene challenge is a Royal Ottawa Health Care Group led initiative to engage the staff, clients and community members to attend to their mental well-being by way of practicing mental hygiene activities for 10 min on a daily basis, throughout the month of March. Participants are encouraged to choose one or many of the practices recommended and do them for about 10 minutes a day. Participants are encouraged to make it their own, in that they can combine the practice or tailor them in a way that suits them best. When signing up for the challenge, participants receive free access to a toolkit with brief outlines and instructional videos on various mental hygiene practices.We also encourage participants to divide the 10 minutes in whatever way best works for them, such as 10 minutes all at once, 5 minutes twice, or even 2 minutes five times. This study aims to expand on the work that was done in 2022 and 2023, when the World Health Organization - 5 Wellbeing Index (WHO-5) and the Warwick Edinburgh Mental Wellbeing Scale (WEMWBS) were collected from participants to ascertain the impact of mental hygiene, by way of including a control group., conditionsModule conditions: Mental Wellbeing, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: SINGLE_GROUP, primaryPurpose: PREVENTION, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: Mental Hygiene, interventions name: Self-Care, outcomesModule primaryOutcomes measure: Change in level of mental wellbeing as measured by the WHO-5 index., primaryOutcomes measure: Change in level of mental wellbeing as measured by the WEMWBS., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06287203, orgStudyIdInfo id: Pro2023001498, secondaryIdInfos id: 3R01DA050721-04S1, type: NIH, link: https://reporter.nih.gov/quickSearch/3R01DA050721-04S1, briefTitle: Novel Prevention Intervention Program to Reduce Risky Patterns of Substance Use Among Emerging Adults, acronym: ARFP, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-20, primaryCompletionDateStruct date: 2024-11-20, completionDateStruct date: 2024-11-20, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Rutgers, The State University of New Jersey, class: OTHER, collaborators name: National Institute on Drug Abuse (NIDA), descriptionModule briefSummary: The purpose of this research study is to test whether completion of a new personalized feedback program is associated with reductions in risky substance use among emerging adults (18-25 years of age)., conditionsModule conditions: Substance Use, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: NONE, maskingDescription: Participants will not be made aware of their condition at baseline; however, they will know their condition once they receives their estimates (or not, in the case of the control condition) and are taken to their follow-up resources., enrollmentInfo count: 450, type: ESTIMATED, armsInterventionsModule interventions name: Addiction Risk Feedback Program, outcomesModule primaryOutcomes measure: Alcohol Consumption, primaryOutcomes measure: Alcohol Problems, primaryOutcomes measure: Drug Use Problems, primaryOutcomes measure: Readiness to change, primaryOutcomes measure: Future substance use intentions, secondaryOutcomes measure: Worry About Substance Use Disorders, secondaryOutcomes measure: Perceived Susceptibility, secondaryOutcomes measure: Well-Being, secondaryOutcomes measure: Anxiety and Depressive Symptoms, secondaryOutcomes measure: Addiction Risk Program Satisfaction, secondaryOutcomes measure: Feelings About Results, secondaryOutcomes measure: Satisfaction with the Assigned Conditions, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 25 Years, stdAges: ADULT, contactsLocationsModule locations facility: Rutgers Robert Wood Johnson Medical School, city: Piscataway, state: New Jersey, zip: 08854, country: United States, contacts name: Emily Balcke, role: CONTACT, email: dnadiscoverystudy@rutgers.edu, contacts name: Danielle Dick, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 40.49927, lon: -74.39904, hasResults: False
protocolSection identificationModule nctId: NCT06287190, orgStudyIdInfo id: Self-confidence assessment, briefTitle: Assessment of Self-Confidence of Dental Interns Regarding Provision of Different Pediatric Dentistry Procedures, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-09-30, completionDateStruct date: 2024-11-30, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-05, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: This study mainly about dental interns testing their knowledge before and after entering the pediatric rotation, conditionsModule conditions: Self Confidence, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 383, type: ESTIMATED, armsInterventionsModule interventions name: Dental interns, outcomesModule primaryOutcomes measure: Self-confidence regarding treatment, secondaryOutcomes measure: difficulties in dental practice through this period, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Cairo University, city: Cairo, country: Egypt, contacts name: Sherine E Eldin, Prof, role: CONTACT, phone: +20 1009073142, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False