hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06295627, orgStudyIdInfo id: SYSKY-2024-115-01, briefTitle: The Analysis of Factors Causing Indwelling Urinary Catheter-related Infections in ICU Patients and Their Nursing Strategies, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-01-30, primaryCompletionDateStruct date: 2023-09-30, completionDateStruct date: 2024-01-15, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, class: OTHER, descriptionModule briefSummary: To explore the analysis of factors causing indwelling urinary catheter-related infections in ICU patients and their nursing strategies, and to provide reference for clinical nursing work. 291 patients with indwelling urinary catheters in the second area of ICU of our hospital from January 1, 2023 to September 30, 2023 were selected as research subjects. They were divided into infection group and non-infection group according to the presence or absence of urinary tract infection. Non-infection group The first group consisted of patients without urinary tract infection (278 cases), and the infection group consisted of patients with urinary tract infection (13 cases). A retrospective analysis method was used to analyze the causes of catheter-related urinary tract infection and the infecting bacteria of the two groups of patients. A single factor analysis was performed on various factors and other related factors, and corresponding nursing strategies were summarized and proposed., conditionsModule conditions: Catheter-associated Urinary Tract Infection, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: RETROSPECTIVE, enrollmentInfo count: 291, type: ACTUAL, armsInterventionsModule interventions name: There were no interventions in retrospective analysis, outcomesModule primaryOutcomes measure: How many patients in the infected group and how many patients in the non-infected group had bladder irrigation, primaryOutcomes measure: How many patients in the infected group and how many patients in the non-infected group were given enema, primaryOutcomes measure: How many times the indwelling catheter was changed in patients in the infected group and patients in the non-infected group respectively, primaryOutcomes measure: How many patients in the infected group and the non-infected group had co-diabetes, eligibilityModule sex: ALL, minimumAge: 15 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Sun Yat-Sen Memorial Hospital, city: Canton, state: Guangdong, zip: 510030, country: China, geoPoint lat: 23.11667, lon: 113.25, hasResults: False
protocolSection identificationModule nctId: NCT06295601, orgStudyIdInfo id: 2024/5591, briefTitle: Telerehabilitation Based Motor Imagery and Action Observation Training in Multiple Sclerosis, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-20, primaryCompletionDateStruct date: 2025-02-15, completionDateStruct date: 2025-08-15, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Inonu University, class: OTHER, descriptionModule briefSummary: This study aims to investigate the effects of the treatment combination consisting of motor imagery and action observation therapy on balance, functional mobility, lower extremity muscle strength, fatigue and quality of life., conditionsModule conditions: Multiple Sclerosis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: INVESTIGATOR, enrollmentInfo count: 10, type: ESTIMATED, armsInterventionsModule interventions name: Traditional rehabilitation, interventions name: Action observation therapy and motor imagery, outcomesModule primaryOutcomes measure: Berg Balance Scale, primaryOutcomes measure: Berg Balance Scale, primaryOutcomes measure: Muscle strength and functional mobility, primaryOutcomes measure: Muscle strength and functional mobility, secondaryOutcomes measure: Fatigue Severity Scale, secondaryOutcomes measure: Fatigue Severity Scale, secondaryOutcomes measure: Multiple Sclerosis International Quality of Life (MusiQoL) questionnaire, secondaryOutcomes measure: Multiple Sclerosis International Quality of Life (MusiQoL) questionnaire, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06295588, orgStudyIdInfo id: STUDY00009135, secondaryIdInfos id: T32CA102618, type: NIH, link: https://reporter.nih.gov/quickSearch/T32CA102618, briefTitle: Clinical Trial of the Seaweed Supplement Fucoidan in Survivors of Cancer, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-15, primaryCompletionDateStruct date: 2025-04-15, completionDateStruct date: 2025-04-15, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: University of Rochester, class: OTHER, collaborators name: National Cancer Institute (NCI), descriptionModule briefSummary: To determine the feasibility of an 8-week fucoidan supplement intervention for patients with fatigue post-cancer treatment and assess changes in fatigue, frailty, and inflammation., conditionsModule conditions: Fatigue, conditions: Inflammation, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Fucoidan extracted from F. Vesiculosus, interventions name: Fucoidan extracted from U. Pinnatifida, outcomesModule primaryOutcomes measure: percentage of participants who are randomized to the study out of all participants approached, primaryOutcomes measure: percentage of participants who start the intervention who go on to complete the 8-week or 16-week intervention, primaryOutcomes measure: percentage of participants who take at least 80% of the fucoidan pills during the study, secondaryOutcomes measure: mean change in Brief Fatigue Inventory, secondaryOutcomes measure: mean change in plasma viscosity in blood, secondaryOutcomes measure: mean change in erythrocyte sedimentation rate in blood, secondaryOutcomes measure: mean change in thyroid stimulating hormone in blood, secondaryOutcomes measure: mean change in C-reactive protein in blood, secondaryOutcomes measure: mean change in leptin in blood, secondaryOutcomes measure: mean change in D Dimer in blood, secondaryOutcomes measure: mean change in TNF alpha in blood, secondaryOutcomes measure: mean change in neopterin in blood, secondaryOutcomes measure: mean change in lactase dehydrogenase in blood, secondaryOutcomes measure: mean change in procalcitonin in blood, secondaryOutcomes measure: mean change in frailty using a modified Fried's Frailty questionnaire, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Rochester Medical Center, city: Rochester, state: New York, zip: 14642, country: United States, geoPoint lat: 43.15478, lon: -77.61556, hasResults: False
protocolSection identificationModule nctId: NCT06295575, orgStudyIdInfo id: ZZhang, briefTitle: Effect of Probiotics on Patients With Congenital Heart Disease Following Cardiopulmonary Bypass, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-06-01, primaryCompletionDateStruct date: 2022-07-01, completionDateStruct date: 2022-07-01, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Nanjing Children's Hospital, class: OTHER, descriptionModule briefSummary: A randomized, controlled study including infants with non-cyanosis congenital heart disease (CHD) in need of surgical correction involving cardiopulmonary bypass (CPB) was established. Infants aged 1 month to 1 years were enrolled between June 2021 and July 2022. The patients in treatment group were supplied with probiotics consisting of Bifidobacterium infantis and Lactobacillus perioperatively and patients in control group were provided with placebo. Data concerning patients' clinical outcome such as diarrhea were collected. Blood samples were collected for measurement of fatty acid binding protein 2 (FABP2), diamine oxidase (DAO), d-lactic acid (D-LA) and C-reactive protein (CRP). Stool samples were collected to investigate the changes of intestinal flora., conditionsModule conditions: Congenital Heart Disease, conditions: Intestinal Disease, conditions: Dysbiosis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 80, type: ACTUAL, armsInterventionsModule interventions name: probiotics containing Bifidobacterium infantis and Lactobacillus, interventions name: placebos containing lactose, outcomesModule primaryOutcomes measure: incidence of morbidity, primaryOutcomes measure: gastrointestinal functional recovery indicators, primaryOutcomes measure: biomarkers, primaryOutcomes measure: microbiome, eligibilityModule sex: ALL, minimumAge: 1 Month, maximumAge: 1 Year, stdAges: CHILD, contactsLocationsModule locations facility: Children's Hospital of Nanjing Medical University, city: Nanjing, state: Jiangsu, zip: 210093, country: China, geoPoint lat: 32.06167, lon: 118.77778, hasResults: False
protocolSection identificationModule nctId: NCT06295562, orgStudyIdInfo id: CMUH112-REC3-201, briefTitle: Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep Apnea, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-07-31, completionDateStruct date: 2025-07-31, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-07, sponsorCollaboratorsModule leadSponsor name: China Medical University Hospital, class: OTHER, descriptionModule briefSummary: This study will recruit 66 patients with obstructive sleep apnea, comprising 33 men and 33 women, who have been referred to the sleep center by their doctors for polysomnograms (PSG). The subjects will undergo two overnight sleep PSG sessions at the sleep center. The interval between the two examinations will be at least 7 days, during which they will receive both a placebo and medication conditions, administered 1 hour before bedtime. The study drugs will include: (1) atomoxetine 80 mg and oxybutynin 5 mg; or (2) venlafaxine 37.5 mg; or (3) atomoxetine 80 mg and trazodone 100 mg. Endotypic traits will be estimated using the Phenotyping Using Polysomnography method. The primary outcome is the change in apnea-hypopnea index, and secondary outcomes include endotypic traits and sleep parameters., conditionsModule conditions: Obstructive Sleep Apnea of Adult, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, enrollmentInfo count: 66, type: ESTIMATED, armsInterventionsModule interventions name: Atomoxetine 80mg combined with oxybutynin 5mg, interventions name: Venlafaxine 37.5mg, interventions name: Atomoxetine 80mg combined with trazodone 100mg, interventions name: Placebo, outcomesModule primaryOutcomes measure: Physiological parameter, secondaryOutcomes measure: Endotypic traits, otherOutcomes measure: Sleep quality, otherOutcomes measure: Waking sleepiness, eligibilityModule sex: ALL, minimumAge: 20 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06295549, orgStudyIdInfo id: LB2304-0001, briefTitle: Targeting CD19/CD20 Dual-targeted Cell in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-25, primaryCompletionDateStruct date: 2026-06-30, completionDateStruct date: 2028-06-30, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: The First Affiliated Hospital with Nanjing Medical University, class: OTHER, collaborators name: Nanjing Legend Biotech Co., descriptionModule briefSummary: A phase I, open-label clinical study to evaluate the safety, tolerability, and efficacy of LUCAR-G39P, a dual-targeted cell preparation targeting CD19/CD20, in patients with relapsed/refractory B-cell non-Hodgkin lymphoma, conditionsModule conditions: Relapsed and Refractory B-cell Non-Hodgkin Lymphoma, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 33, type: ESTIMATED, armsInterventionsModule interventions name: LUCAR-G39P cells product, outcomesModule primaryOutcomes measure: Incidence, severity and type of TEAEs, primaryOutcomes measure: Pharmacokinetics in peripheral blood, primaryOutcomes measure: Pharmacokinetics in bone marrow, primaryOutcomes measure: The recommended Phase II dose (RP2D) for this cell therapy, secondaryOutcomes measure: Overall Response Rate (ORR), secondaryOutcomes measure: Progression-free survival (PFS), secondaryOutcomes measure: Overall Survival (OS), secondaryOutcomes measure: Time to Response (TTR), secondaryOutcomes measure: Duration of Response (DoR), secondaryOutcomes measure: Immunogenicity assessment of LUCAR-G39P cells, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Department of Haematology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, status: RECRUITING, city: Nanjin, state: Jiangsu, zip: 210029, country: China, contacts name: Huayuan Zhu, PhD，MD, role: CONTACT, phone: 86 25 68306034, email: huayuan.zhu@hotmail.com, contacts name: Yeqin Sha, MD, role: CONTACT, email: yeqinsha@njmu.edu.cn, hasResults: False
protocolSection identificationModule nctId: NCT06295536, orgStudyIdInfo id: WS10363, briefTitle: Optimization of a Photoretinoscopy Method for Determining the Objective Refraction of Children, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2024-08, completionDateStruct date: 2024-08, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Essilor International, class: INDUSTRY, descriptionModule briefSummary: The objective is to compare the refractive parameters of the photorefraction prototype device without cycloplegia with the refractive parameters of reference device, an autorefractometer with and without cycloplegia., conditionsModule conditions: Ametropia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: SCREENING, maskingInfo masking: NONE, enrollmentInfo count: 115, type: ESTIMATED, armsInterventionsModule interventions name: Comparator device, Closed-field autorefractometer, outcomesModule primaryOutcomes measure: Objective refractive error, eligibilityModule sex: ALL, minimumAge: 6 Years, maximumAge: 13 Years, stdAges: CHILD, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06295523, orgStudyIdInfo id: STU_2019_1759_COPD, briefTitle: Heat Waves and the Elderly With COPD, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2025-12, completionDateStruct date: 2025-12, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: University of Texas Southwestern Medical Center, class: OTHER, collaborators name: American Heart Association, descriptionModule briefSummary: The purpose of this study is to investigate thermoregulatory responses in older individuals with COPD., conditionsModule conditions: COPD, conditions: Aging, conditions: Hyperthermia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 44, type: ESTIMATED, armsInterventionsModule interventions name: Water Spray, interventions name: Control, outcomesModule primaryOutcomes measure: Core body temperature, primaryOutcomes measure: Forced expiratory volume (FEV1), primaryOutcomes measure: Forced vital capacity (FVC), primaryOutcomes measure: FEV1/FVC ratio, eligibilityModule sex: ALL, minimumAge: 65 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Texas Health Presbyterian Hospital Dallas, status: RECRUITING, city: Dallas, state: Texas, zip: 75231, country: United States, contacts name: Whitley Atkins, PhD, role: CONTACT, contacts name: Courtney Kirby, BS RN, role: CONTACT, phone: 214-345-6502, contacts name: Craig Crandall, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 32.78306, lon: -96.80667, hasResults: False
protocolSection identificationModule nctId: NCT06295510, orgStudyIdInfo id: CDUTCM20240223, briefTitle: Observational Study of the Association Between Food Intake and Endometrial Polyps, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-04-01, completionDateStruct date: 2024-05-01, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: qinxiu zhang, class: OTHER, descriptionModule briefSummary: There are currently no studies evaluating the association between diet and the incidence of endometrial polyps. We aim to evaluate the association to provide more recommendations for the early prevention of endometrial polyps., conditionsModule conditions: Diet Habit, conditions: Endometrial Polyp, conditions: Women, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: RETROSPECTIVE, enrollmentInfo count: 150, type: ESTIMATED, armsInterventionsModule interventions name: No interventions., outcomesModule primaryOutcomes measure: Hormonal dietary intake, primaryOutcomes measure: Comparison of daily living habits, eligibilityModule sex: FEMALE, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06295471, orgStudyIdInfo id: 2024P000112, briefTitle: A Comparative Clinical Study to Assess Pain Score and Wound Healing Following Fractional Ablation With a DFG Laser and CO2 Laser, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2024-08, completionDateStruct date: 2024-08, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Massachusetts General Hospital, class: OTHER, descriptionModule briefSummary: This research study aims assess whether the Difference Frequency Generation (DFG) laser could be a better alternative to the CO2 laser in terms of reduced side effects and patient downtime., conditionsModule conditions: Healthy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 23, type: ESTIMATED, armsInterventionsModule interventions name: DFG Laser, interventions name: CO2 Laser, interventions name: Optical coherence tomography (OCT), outcomesModule primaryOutcomes measure: Visual Analog Scale (VAS) pain score, primaryOutcomes measure: Wound healing time, secondaryOutcomes measure: Vessel density via OCT imaging, secondaryOutcomes measure: Vessel length via OCT imaging, secondaryOutcomes measure: Vessel thickness via OCT imaging, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: MGH Clinical Unit for Research Trials & Outcomes in Skin, city: Boston, state: Massachusetts, zip: 02114, country: United States, contacts name: Alicia Van Cott, MSN, role: CONTACT, phone: 617-726-4454, email: avancott@mgb.org, contacts name: Abigail Carlson, BS, role: CONTACT, phone: 617-726-4454, email: acarlson9@mgh.harvard.edu, geoPoint lat: 42.35843, lon: -71.05977, hasResults: False
protocolSection identificationModule nctId: NCT06295445, orgStudyIdInfo id: Cardiopulmonary Ultrasound, briefTitle: Impact of Integrated Cardiopulmonary Ultrasound on Clinical Outcome of Shocked Patients in Intensive Care Unit, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-03-01, primaryCompletionDateStruct date: 2023-09-01, completionDateStruct date: 2023-09-15, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Egymedicalpedia, class: INDUSTRY, descriptionModule briefSummary: Shock is one of the most common conditions in the intensive care unit (ICU) affecting one-third of critically ill patients. It reduces oxygen and nutrition's perfusion to the solid organs and is closely associated with increased mortality. Most literature has described how hemodynamic monitoring could provide an effective way to identify underlying pathophysiological processes and guide appropriate therapy in shock patients., conditionsModule conditions: Shock, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: DIAGNOSTIC, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 108, type: ACTUAL, armsInterventionsModule interventions name: care cardio-pulmonary ultrasound, interventions name: treatment without any use of point of care cardio-pulmonary ultrasound scans for guidance of the management, outcomesModule primaryOutcomes measure: Mortality rate, primaryOutcomes measure: Number of mortalities, eligibilityModule sex: ALL, minimumAge: 19 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule locations facility: Al-Azhar University hospitals, city: Cairo, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False