hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06338540, orgStudyIdInfo id: A26020822, briefTitle: Relation of Caries Color to Caries Severity and Its Microbial Load, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2022-09-01, primaryCompletionDateStruct date: 2024-01-01, completionDateStruct date: 2024-07-01, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: Mansoura University, class: OTHER, descriptionModule briefSummary: This study is to find the relation of caries color to caries severity and its microbial load in primary molars., conditionsModule conditions: Relation of Caries Color, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Group 1: Yellow caries color Group 2: dark brown caries color Group 3: light brown caries color Group 4: black caries color, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Black color of caries, interventions name: dark brown color of caries, interventions name: light brown color of caries, interventions name: yellow color of caries, outcomesModule primaryOutcomes measure: Caries color related to history of pain, primaryOutcomes measure: Caries color related to ICDAS, primaryOutcomes measure: Caries color related to pulp exposed, primaryOutcomes measure: Caries color related to microbial load, eligibilityModule sex: ALL, minimumAge: 4 Years, maximumAge: 7 Years, stdAges: CHILD, contactsLocationsModule locations facility: Mansoura university, city: Mansoura, state: Dakahlia, zip: 35511, country: Egypt, geoPoint lat: 31.03637, lon: 31.38069, hasResults: False
protocolSection identificationModule nctId: NCT06338527, orgStudyIdInfo id: 2024YX321, briefTitle: Effects of Aromatherapy on Patients Undergoing Chemotherapy for Breast Cancer, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-26, primaryCompletionDateStruct date: 2024-06-01, completionDateStruct date: 2024-06-15, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: Weifang Medical University, class: OTHER, descriptionModule briefSummary: The objective of this study was to investigate the effects of aromatherapy on sleep quality and anxiety in patients undergoing chemotherapy for breast cancer., conditionsModule conditions: Sleep Quality, conditions: Anxiety, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 90, type: ESTIMATED, armsInterventionsModule interventions name: Aromatherapy, interventions name: No intervention, outcomesModule primaryOutcomes measure: Sleep quality, primaryOutcomes measure: Anxiety, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Weifang People's Hospital, city: Weifang, state: Shangdong, zip: 261000, country: China, contacts name: Shirong Fang, M.D., role: CONTACT, email: fsr0536@163.com, geoPoint lat: 36.71, lon: 119.10194, hasResults: False
protocolSection identificationModule nctId: NCT06338514, orgStudyIdInfo id: KutahyaHSU-DRYNEEDLE-dorsalgia, briefTitle: The Effectiveness of Dry Needling Treatment in Patients Diagnosed With Dorsal Myofascial Pain Syndrome., statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-25, primaryCompletionDateStruct date: 2024-06-25, completionDateStruct date: 2024-06-25, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: Kutahya Health Sciences University, class: OTHER, descriptionModule briefSummary: Back pain is commonly seen in the working-age population, with the peak occurrence around the age of 40. Its frequency does not increase with age and is not associated with age-related degenerative changes in the spine. Especially when the underlying cause is conditions such as myofascial pain syndrome (MPS), where regional muscle sensitivity in the rhomboid and trapezius areas is prominent, dry needling treatment has become increasingly popular and the subject of numerous studies in recent years. In the diagnosis of MPS, two valuable findings include the detection of a taut band upon palpation and the presence of trigger points in muscle fibers with mild finger pressure. The study we are planning involves a double-blind efficacy trial where real and sham dry needling procedures will be performed under ultrasound guidance, ensuring that both the patient and the evaluator are blinded. This study design has the potential to make a significant contribution to the literature in this field., conditionsModule conditions: Myofascial Trigger Point Pain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: A two-group, sham-controlled, double-blind, prospective, randomized controlled trial, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, maskingDescription: In the dry needling application, patients will be blinded to the groups they are randomized into. The evaluator will also be unaware of which group the patients belong to. The practitioner will perform the procedures in both groups using ultrasound guidance, targeting the standard trigger points in the painful dorsal trapezius and rhomboid muscles in the study group, and targeting subcutaneous fatty tissue in the same regions in the sham group., whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Real dry needling, interventions name: Sham dry needling, outcomesModule primaryOutcomes measure: Visual Analog Scale, primaryOutcomes measure: Patient-Specific Functional Scale, primaryOutcomes measure: Pressure Pain Threshold Measurement, secondaryOutcomes measure: What does Oswestry stand for? The Oswestry Disability Index (ODI), secondaryOutcomes measure: The 12-item Short-Form Health Survey version 2 (SF-12v2), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06338475, orgStudyIdInfo id: 20205703, briefTitle: A Biobehavioral Intervention for Latino/Hispanic Young Adults With Cancer, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2026-06, completionDateStruct date: 2026-06, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: University of California, Irvine, class: OTHER, descriptionModule briefSummary: Building upon the results of a single-arm trial designed to investigate the feasibility and acceptability of a novel intervention, Goal-focused Emotion-Regulation Therapy (GET), this trial is a randomized-controlled biobehavioral pilot trial of GET versus a time-and attention matched control (Instrumental Supportive Listening; ISL) in Latino/Hispanic young adult cancer survivors. Outcomes include improved distress symptoms, emotion regulation, goal navigation skills, and changes in stress-sensitive biomarkers.Participants will be randomized to receive six sessions of GET or ISL delivered over eight weeks. In addition to indicators of intervention feasibility, the investigators will measure primary and secondary psychological outcomes prior to (T0), immediately after (T1), and twelve weeks after intervention (T2). Additionally, identified biomarkers will be measured at baseline and at T1, and T2., conditionsModule conditions: Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Goal-Focused Emotion-Regulation Therapy (GET), interventions name: Individual Supportive Listening (ISL), outcomesModule primaryOutcomes measure: Change in Hospital Anxiety and Depression Scale (HADS), primaryOutcomes measure: Change in Systemic Pro-inflammatory Cytokine Levels (IL-6, IL-1ra, C-reactive Protein (CRP), sTNFαRII), primaryOutcomes measure: Change in Salivary Diurnal Cortisol Slope and Daily Output, secondaryOutcomes measure: Change in Functional Assessment of Chronic Illness Therapy - Spiritual Well-Being (FACIT-Sp) Subscale Score, secondaryOutcomes measure: Change in Career Thoughts Inventory (CTI) Global Score, secondaryOutcomes measure: Change in Emotion Regulation Questionnaire (ERQ) Scale Scores, secondaryOutcomes measure: Change in Cancer Assessment for Young Adults (CAYA-T) - Goal Navigation Score, secondaryOutcomes measure: Change in Emotional Approach Coping Questionnaire (EAC) Scale Scores, eligibilityModule sex: MALE, minimumAge: 18 Years, maximumAge: 39 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06338462, orgStudyIdInfo id: 2000034128, secondaryIdInfos id: R21AI174129, type: NIH, link: https://reporter.nih.gov/quickSearch/R21AI174129, briefTitle: Cali Sin Tos Aim 2, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2025-05, completionDateStruct date: 2025-05, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: Yale University, class: OTHER, collaborators name: National Institute of Allergy and Infectious Diseases (NIAID), descriptionModule briefSummary: The overall objective of this Aim is to design and iteratively adapt a home-based, mHealth- and oral testing facilitated strategy for implementing tuberculosis (TB) contact tracing in Cali, Colombia. Investigators will employ an iterative, community-engaged, participatory co-design process to optimize the feasibility, acceptability, usability, and appropriateness of the mobile health (mHealth) and oral testing strategy, in preparation for a future, appropriately powered implementation-effectiveness trial.This protocol includes the baseline contact tracing protocol and the procedures for determining adaptations to the mHealth strategy (i.e., nominal group technique)., conditionsModule conditions: Tuberculosis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: target sample size is an anticipated 120 index persons with TB enrolled over three design cycles, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: Chatbot, interventions name: Oral testing, outcomesModule primaryOutcomes measure: Implementation of the mHealth strategy to assess feasibility., primaryOutcomes measure: Oral specimen collection to assess feasibility., eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Centro Internacional de Entrenamiento e Investigaciones Medicas (CIDIEM), city: Cali, country: Colombia, geoPoint lat: 3.43722, lon: -76.5225, hasResults: False
protocolSection identificationModule nctId: NCT06338436, orgStudyIdInfo id: VAR-2022-05, briefTitle: Varian ProBeam Proton Therapy System China Clinical Trial (Guangzhou), statusModule overallStatus: COMPLETED, startDateStruct date: 2022-12-21, primaryCompletionDateStruct date: 2023-09-26, completionDateStruct date: 2023-11-13, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-04-02, sponsorCollaboratorsModule leadSponsor name: Varian, a Siemens Healthineers Company, class: INDUSTRY, descriptionModule briefSummary: This study is prospective, single-center, single-arm objective performance criteria.This trial will be conducted with a total of 47 subjects enrolled. All of subjects will be treated with radiation therapy using the medical device Varian ProBeam Proton Therapy System (ProBeam), aim to compare the data with objective performance criteria (OPC) to evaluate the effectiveness and safety of ProBeam radiotherapy system for oncology patients, providing a clinical basis for the medical device registration., conditionsModule conditions: Tumor, Solid, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: a clinical study of prospective, single-arm objective performance criteria, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 47, type: ACTUAL, armsInterventionsModule interventions name: Proton Radiation Therapy System (ProBeam), outcomesModule primaryOutcomes measure: Effectiveness evaluation: Local tumor control rate 90 days after the proton radiation treatment completion, primaryOutcomes measure: Safety evaluation: Incidence of Acute radiation injury, primaryOutcomes measure: Safety evaluation: Incidence of Adverse Events based on CTCAE 5.0 criteria, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, city: Guangzhou, state: Guangdong, country: China, geoPoint lat: 23.11667, lon: 113.25, hasResults: False
protocolSection identificationModule nctId: NCT06338410, orgStudyIdInfo id: UHS/Education/126-24/131, briefTitle: Effect of Kangaroo Mother Care on Oxidative Stress and Bonding, acronym: KMC, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-08-01, primaryCompletionDateStruct date: 2024-03-20, completionDateStruct date: 2024-03-20, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-04-01, sponsorCollaboratorsModule leadSponsor name: University of Health Sciences Lahore, class: OTHER, collaborators name: Services Hospital, Lahore, descriptionModule briefSummary: The goal of this clinical trial is to learn if Kangaroo Mother care can have effect on oxidative stress in premature neonates. It will also learn about the bonding between mother and her premature infant. The main questions it aims to answer are:* Does Kangaroo mother care lower the biomarker of oxidative stress in premature neonates?* Is Kangaroo mother care associated with mother-infant bonding? Researchers will compare Kangaroo mother care to Conventional incubator care to see if Kangaroo mother care works to have effect on oxidative stress.Participants will be:* given Kangaroo mother care on third day of life or standard incubator care for one hour* Urine sample for oxidative stress biomarker will be collected via noninvasive method before and after Kangaroo mother care or conventional incubator care from premature neonates.* Mother-infant bonding scale will be filled by mothers of enrolled premature infants before and after kangaroo mother care and conventional incubator care, conditionsModule conditions: Kangaroo Mother Care, conditions: Oxidative Stress, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ACTUAL, armsInterventionsModule interventions name: Kangaroo Mother Care, outcomesModule primaryOutcomes measure: biomarker of Oxidative Stress (Allantoin) in urine sample of premature infants, primaryOutcomes measure: Mother- Infant Bonding, eligibilityModule sex: ALL, minimumAge: 3 Days, maximumAge: 3 Days, stdAges: CHILD, contactsLocationsModule locations facility: Services Hospital, Lahore, city: Lahore, state: Punjab, zip: 54000, country: Pakistan, geoPoint lat: 31.558, lon: 74.35071, hasResults: False
protocolSection identificationModule nctId: NCT06338397, orgStudyIdInfo id: 2023_0455, briefTitle: Social & Affective Cognition in Alzheimer's Disease & Associated Disorders, acronym: SOCIALIZE, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-02, primaryCompletionDateStruct date: 2027-05-02, completionDateStruct date: 2027-05-02, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: University Hospital, Lille, class: OTHER, collaborators name: France Alzheimer, descriptionModule briefSummary: Recent studies have shown that individual neuropsychological scores of patients with Alzheimer's disease and Associated Disorders (ADAD) are only poorly correlated to their behavioral difficulties, such as disinhibition, apathy, social decision-making or vulnerability. Recently, social \& affective cognitive disorders have been highlighted as potential cause of social behavioral abnormalities. However, no previous studies have assessed the specific relationship between social \& affective cognition \& social behavior in ADAD. Our pilot study aims to explore the correlations between core and extended social \& affective cognitive processes and social behavior as observed during the neuropsychological examination, as well as to explore the common brain regions involved in those domains., conditionsModule conditions: Alzheimer's Disease, conditions: Frontotemporal Degeneration (Semantic & Behavioral Variants), designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: SCANN, outcomesModule primaryOutcomes measure: Correlation coefficient between the mini Social cognition & Emotional Assessment - mini-SEA - total score and the Social Behavior Observer Checklist - SBOC - score in all participants., secondaryOutcomes measure: Correlation coefficients between the mini Social cognition & Emotional Assessment - mini-SEA - sub scores and the neuropsychological assessment (as measured by the Social Behavior Observer Checklist - SBOC - score in all participants., secondaryOutcomes measure: Correlation coefficient between the SBOC score with MRI markers in all participants, secondaryOutcomes measure: Correlation coefficient between mini-SEA sub scores & MRI markers in all participants., secondaryOutcomes measure: Correlation coefficients between mini-SEA sub scores with the SOCIAL50, CBI, ZBS, CSDC, SVS scales in each ADAD and controls groups., secondaryOutcomes measure: Correlation coefficients between SCANN sub-scores and the SBOC, SOCIAL50, CBI, ZBS, CSDC, SVS scales in each ADAD and controls groups., eligibilityModule sex: ALL, minimumAge: 40 Years, maximumAge: 85 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06338384, orgStudyIdInfo id: 44735129, briefTitle: Examining Engagement Trends Among Participants in Peripheral Neuropathy Clinical Research, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2025-04, primaryCompletionDateStruct date: 2026-04, completionDateStruct date: 2027-04, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: Power Life Sciences Inc., class: INDUSTRY, descriptionModule briefSummary: This trial aims to uncover the factors driving patient decisions regarding enrollment, withdrawal, or re-engagement in peripheral neuropathy clinical trials. Understanding these factors will significantly improve the relevance and effectiveness of future research endeavors.Ultimately, this trial endeavors to deepen our understanding of the factors impacting peripheral neuropathy clinical trial participation. Enhancing participation rates could accelerate the development of innovative treatments for this debilitating condition., conditionsModule conditions: Peripheral Neuropathy, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CROSSOVER, timePerspective: PROSPECTIVE, enrollmentInfo count: 500, type: ESTIMATED, outcomesModule primaryOutcomes measure: Number of peripheral neuropathy patients who decide to enroll in a clinical research, primaryOutcomes measure: Rate of peripheral neuropathy patients who remain in clinical trial to trial completion, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Power Life Sciences, city: San Francisco, state: California, zip: 94107, country: United States, contacts name: Michael B Gill, role: CONTACT, phone: 415-900-4227, email: https://www.withpower.com/contact-us@withpower.com, geoPoint lat: 37.77493, lon: -122.41942, documentSection largeDocumentModule largeDocs typeAbbrev: ICF, hasProtocol: False, hasSap: False, hasIcf: True, label: Informed Consent Form, date: 2024-03-22, uploadDate: 2024-03-22T09:04, filename: ICF_000.pdf, size: 67357, hasResults: False
protocolSection identificationModule nctId: NCT06338371, orgStudyIdInfo id: IZTU-TEKBAŞ-001, briefTitle: Effect of Pelvic Floor Muscle Exercise on Sexual Function, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-11-01, primaryCompletionDateStruct date: 2022-04-06, completionDateStruct date: 2022-05-06, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: Serap Tekbas, class: OTHER, descriptionModule briefSummary: The goal of this evaluate the effect of pelvic floor muscle exercises on sexual function in women of reproductive age. A randomized controlled trial was conducted in a sample of women of reproductive age, 77 women were randomly assigned to control (n=39) and training (n=38) groups. A form including questions regarding socio-demographic characteristics and the Female Sexual Function Index was applied to all women included in the study. Pelvic floor exercise training was given to the women in the training group and the Female Sexual Function Index was applied to both groups in the 1st, 2nd, and 3rd months. The differences between those who received and those who did not receive training and the effects of regular pelvic exercise on sexual function were evaluated by month.Research Hypotheses H1: Sexual function scores of women of reproductive age who regularly perform pelvic floor muscle exercises are higher than those who do not exercise.H2: Sexual function scores are higher for those who regularly exercise their pelvic floor muscles for at least two months, conditionsModule conditions: Pelvic Floor Muscle Weakness, conditions: Sexuality, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 77, type: ACTUAL, armsInterventionsModule interventions name: Pelvic Floor exercise training, outcomesModule primaryOutcomes measure: Determining Number of Participants, primaryOutcomes measure: Initial scale application, primaryOutcomes measure: Distribution of participants into groups, secondaryOutcomes measure: Providing pelvic floor exercise for training group, secondaryOutcomes measure: Female Sexual Function Index, secondaryOutcomes measure: Female Sexual Function Index, secondaryOutcomes measure: Female Sexual Function Index, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 49 Years, stdAges: ADULT, contactsLocationsModule locations facility: Izmir Tinaztepe University, city: İzmir, state: Buca, zip: 35400, country: Turkey, geoPoint lat: 38.41273, lon: 27.13838, hasResults: False