hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06366763, orgStudyIdInfo id: ChengduUTCMvs5, briefTitle: Comparative Clinical Efficacy Between Multi-layer Bandage Pressure Therapy and Gradient Pressure Elastic Stocking Treatment After Endovenous Radiofrequency Ablation, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-08-01, primaryCompletionDateStruct date: 2024-08-01, completionDateStruct date: 2024-08-01, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Chengdu University of Traditional Chinese Medicine, class: OTHER, descriptionModule briefSummary: Objective: To assess the clinical efficacy of different compression methods within 48 hours after endovenous radiofrequency ablation (RFA) in terms of great saphenous vein closure rate, postoperative complications, quality of life, time to return to normal work, and patient satisfaction., conditionsModule conditions: Vascular Diseases, Peripheral, conditions: Venous Insufficiency of Leg, conditions: Varicose Veins of Lower Limb, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: Among the 210 patients included in the study (82 males, 128 females; average age of 59 years), 7 patients were lost to follow-up, and the remaining patients completed the treatment and follow-up.To assess the clinical efficacy of different compression methods within 48 hours after endovenous radiofrequency ablation (RFA) in terms of great saphenous vein closure rate, postoperative complications, quality of life, time to return to normal work, and patient satisfaction., primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 210, type: ESTIMATED, armsInterventionsModule interventions name: Questionnaires, outcomesModule primaryOutcomes measure: Pain after radiofrequency ablation, primaryOutcomes measure: Bleeding after radiofrequency ablation, primaryOutcomes measure: Tension blisters after radiofrequency ablation, secondaryOutcomes measure: The rate of occlusion of treated vein post-procedure, secondaryOutcomes measure: Quality of life score using the Chronic Venous Insufficiency Questionnaire(CIVIQ-14), secondaryOutcomes measure: Clinical Change using Venous Clinical Severity Score (VCSS), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hospital of Chengdu University of Traditional Chinese Medicine, status: RECRUITING, city: Chengdu, state: Sichuan, zip: 610000, country: China, contacts name: Chunshui He, Doctor, role: CONTACT, phone: 86-18981885601, email: chunshuihe@msn.com, contacts name: Qiqi Wangqiqi, Master, role: CONTACT, phone: 86-15184495605, email: 285510746@qq.com, geoPoint lat: 30.66667, lon: 104.06667, hasResults: False
protocolSection identificationModule nctId: NCT06366737, orgStudyIdInfo id: CEBD-CU-2024-03-02, briefTitle: En-mass Retraction by Lingual Retractor Versus Clear Aligner Appliances, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2025-03, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: en-mass retraction by lingual retractor versus clear alighner therapy, conditionsModule conditions: Maxillary Prognathism, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Lingual Retractor Appliance, interventions name: clear aligner, outcomesModule primaryOutcomes measure: patient satisfaction ( time, cost, quality), secondaryOutcomes measure: inclination of upper anterior teeth, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Faculty of Dentistry, city: Cairo, country: Egypt, contacts name: zainab abdulrhman, role: CONTACT, phone: 00201092445775, email: zeinab_mohammed@dentistry.cu.edu.eg, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06366672, orgStudyIdInfo id: 202312043, briefTitle: Evaluating the Human Immune Response to the JYNNEOS Vaccine, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06, primaryCompletionDateStruct date: 2025-12, completionDateStruct date: 2025-12, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Washington University School of Medicine, class: OTHER, descriptionModule briefSummary: This study is designed to evaluate the magnitude and duration of the human adaptive immune response to the JYNNEOS Modified Vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccine in the blood, lung mucosa, skin and bone marrow., conditionsModule conditions: Vaccinia, conditions: Virus Diseases, designModule studyType: INTERVENTIONAL, phases: EARLY_PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: Participants will be vaccinated with MVA-BN according to the FDA-approved labeling and immune responses in the blood, lung mucosa, skin, and bone marrow will be monitored prior to and following vaccination using phlebotomy, research bronchoscopy, skin punch biopsy, and bone marrow aspiration procedures., primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) suspension for subcutaneous injection, interventions name: Phlebotomy, interventions name: Research bronchoscopy, interventions name: Skin punch biopsy, interventions name: Bone marrow aspiration, outcomesModule primaryOutcomes measure: Change in magnitude of the MVA-BN antigen-specific T cell response in the blood, primaryOutcomes measure: Change in magnitude of the MVA-BN antigen-specific antibody response in blood plasma, secondaryOutcomes measure: Change in magnitude of the MVA-BN antigen-specific T cell response in the lower airways, secondaryOutcomes measure: Change in magnitude of the MVA-BN antigen-specific antibody response in bronchoalveolar lavage fluid, otherOutcomes measure: Evaluate the magnitude and surface phenotype of T cells in the blood, airspace, and skin over time, otherOutcomes measure: Evaluate the magnitude and surface phenotype of B cells in the blood and bone marrow over time., eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Washington University in Saint Louis School of Medicine Emergency Care and Research Core, city: Saint Louis, state: Missouri, zip: 63110, country: United States, contacts name: Jamie Mills, role: CONTACT, phone: 314-305-1054, email: jamiem@wustl.edu, geoPoint lat: 38.62727, lon: -90.19789, hasResults: False
protocolSection identificationModule nctId: NCT06366659, orgStudyIdInfo id: M2024049, briefTitle: Unraveling the Pathogenesis of Pruritus in Intrahepatic Cholestasis of Pregnancy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-20, primaryCompletionDateStruct date: 2025-08-20, completionDateStruct date: 2025-08-20, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Peking University, class: OTHER, collaborators name: Peking University Third Hospital, descriptionModule briefSummary: This study hopes identify the main pruritogens of ICP pruritus and provide new insights for the diagnosis, prediction, and treatment of ICP. Details are as follows: It is planned to include ICP confirmed pregnant women and healthy pregnant women who have given birth in the Peking University Third Hospital and Sichuan University West China Second University Hospital. Then progesterone sulfate levels in plasma samples will be quantified by High Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) and itch intensity will be quantified by questionnaires. Main study endpoint: To reveal new indicators of ICP diagnosis with high accuracy: single, multiple or combined indicators of progesterone sulfates and other molecules like bile acids; Secondary study endpoint: To determine whether progesterone sulfates can be used as an early screening indicator for ICP for disease prediction, specifically whether elevated levels of progesterone sulfates predate pruritus in pregnant women with ICP., conditionsModule conditions: Intrahepatic Cholestasis of Pregnancy, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 600, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Progesterone metabolites (levels in plasma), primaryOutcomes measure: Itch intensity, secondaryOutcomes measure: Total bile acids (levels in plasma), eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 35 Years, stdAges: ADULT, contactsLocationsModule locations facility: Peking University Third Hospital, city: Beijing, state: Beijing, zip: 100000, country: China, contacts name: Guangyi Lan, role: CONTACT, phone: 13176881226, email: Guangyi_lan@stu.pku.edu.cn, contacts name: Yulong Li, role: PRINCIPAL_INVESTIGATOR, contacts name: Yuan Wei, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 39.9075, lon: 116.39723, locations facility: Sichuan University West China Second University Hospital, city: Chengdu, state: Sichuan, zip: 610001, country: China, contacts name: Guangyi Lan, role: CONTACT, phone: 13176881226, email: Guangyi_lan@stu.pku.edu.cn, contacts name: Yaoyao Zhang, role: PRINCIPAL_INVESTIGATOR, contacts name: Xue Xiao, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 30.66667, lon: 104.06667, hasResults: False
protocolSection identificationModule nctId: NCT06366646, orgStudyIdInfo id: 035901, briefTitle: Competency-based Intervention for Head Nurses, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-12-01, primaryCompletionDateStruct date: 2023-04-30, completionDateStruct date: 2023-04-30, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Matrouh University, class: OTHER, descriptionModule briefSummary: Head nurses have a crucial leadership role in managing their units and providing high-quality and safe nursing care. Head nurse leadership competency and effectiveness are very essential to manage nursing care practices and management activities in their hospitals. Development leadership competency intervention programs would improve the head nurse's competency and effectiveness., conditionsModule conditions: Intervention, conditions: Knowledge, Attitudes, Practice, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: A quasi-experimental design, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: SINGLE, maskingDescription: A quasi-experimental design utilized one group for pre-, post, and follow-up intervention., whoMasked: PARTICIPANT, enrollmentInfo count: 90, type: ACTUAL, armsInterventionsModule interventions name: Competency-based intervention, outcomesModule primaryOutcomes measure: Questionnaire to measure head nurses' knowledge of leadership competency, primaryOutcomes measure: Questionnaire to measure head nurses' ability to use leadership competency, primaryOutcomes measure: Questionnaire to measure leadership effectiveness, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Faculty of Nursing, Matrouh University, city: Mersa Matruh, zip: 002, country: Egypt, geoPoint lat: 31.3529, lon: 27.23725, hasResults: False
protocolSection identificationModule nctId: NCT06366620, orgStudyIdInfo id: STUDY00003416, briefTitle: Examining the Feasibility, Acceptability, and Fidelity of Utilizing Parent Training Graduates as Peer Supports, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-10, primaryCompletionDateStruct date: 2024-06-19, completionDateStruct date: 2024-06-19, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Seattle Children's Hospital, class: OTHER, descriptionModule briefSummary: Disruptive behavioral disorders are common in early childhood, affecting up to 15% of preschool-aged children. Behavioral parent training programs are a first-line evidence-based treatment for child disruptive behaviors. There is evidence showing that (a) these programs are effective in reducing disruptive behavior and improving long-term outcomes, and (b) there is an excellent return on investment for early intervention. Nevertheless, there is limited availability of behavioral parent training programs, particularly in rural settings, due to shortages of trained clinicians. Thus, there is a pressing need for expanding the mental healthcare workforce in rural/underserved areas. The study will involve an established parent-based behavioral intervention (First Approach Skills Training for Behavior; or FAST-B) with added pilot component incorporating parents who have previously been through parent behavioral management training programs as Peer Supports., conditionsModule conditions: Child Disruptive Behavior Disorders, conditions: Parent Child Relationship, conditions: Parent Management Training, conditions: Peer Support, conditions: Child Behavior Problems, conditions: Challenging Behavior, conditions: Positive Parenting, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: SINGLE_GROUP, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: FAST-B PEERS, interventions name: FAST-B (First Approach Skills Training - Behavior), outcomesModule primaryOutcomes measure: Acceptability of FAST-B PEERS, primaryOutcomes measure: Acceptability of FAST-B, primaryOutcomes measure: FAST-B PEERS support calls attended, secondaryOutcomes measure: Weekly Assessment of Child Behavior - P, secondaryOutcomes measure: Coping with Child Negative Emotions Scale, secondaryOutcomes measure: Strengths and Difficulties Questionnaire, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Seattle Children's, status: RECRUITING, city: Seattle, state: Washington, zip: 98115, country: United States, contacts name: Doug Mason, role: CONTACT, phone: 206-987-7000, email: doug.mason@seattlechildrens.org, contacts name: Alissa D Hemke, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 47.60621, lon: -122.33207, hasResults: False
protocolSection identificationModule nctId: NCT06366607, orgStudyIdInfo id: 0306066, briefTitle: Managing High-alert Medication Administration and Errors, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-03-01, primaryCompletionDateStruct date: 2023-05-31, completionDateStruct date: 2023-05-31, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Matrouh University, class: OTHER, descriptionModule briefSummary: High-alert medications are drugs that may lead to serious harm when they are wrongly administered to patients. Safe medication administration is the crucial role of nursing staff., conditionsModule conditions: Knowledge, conditions: Practice Nurse's Scope, conditions: Competence, conditions: Nurse's Role, conditions: Error Disclosure, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 300, type: ACTUAL, armsInterventionsModule interventions name: high-alert medication administration, outcomesModule primaryOutcomes measure: Questionnaire to measure nurses' knowledge about high-alert medication administration, primaryOutcomes measure: Questionnaire to measure medication safety climate, primaryOutcomes measure: Questionnaire to measure nurses' competency, primaryOutcomes measure: observational check list to measure nurses' practice during administration of high-alert medications, primaryOutcomes measure: Questionnaire to measure errors associated with administering high-alert medications, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Faculty of Nursing, Matrouh University, city: Mersa Matruh, zip: 002, country: Egypt, geoPoint lat: 31.3529, lon: 27.23725, hasResults: False
protocolSection identificationModule nctId: NCT06366594, orgStudyIdInfo id: 0305897, briefTitle: First-line Nurse Manager Authentic Leadership Training Program, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-12-01, primaryCompletionDateStruct date: 2023-04-30, completionDateStruct date: 2023-04-30, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Matrouh University, class: OTHER, descriptionModule briefSummary: Authentic leadership behavior is considered a mandatory strategy for enhancing the nurse manager capabilities and practice as well as achieving positive nurses' attitudes., conditionsModule conditions: Intervention, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: SINGLE_GROUP, interventionModelDescription: A quasi-experimental research design, primaryPurpose: OTHER, maskingInfo masking: SINGLE, maskingDescription: A quasi-experimental design utilized one group for pre-, post, and follow-up intervention., whoMasked: PARTICIPANT, enrollmentInfo count: 37, type: ACTUAL, armsInterventionsModule interventions name: Authentic leadership training program, outcomesModule primaryOutcomes measure: Questionnaire to measure first-line nurse managers' knowledge about authentic leadership, primaryOutcomes measure: questionnaire to measure authentic leadership behavior among first-line nurse managers, primaryOutcomes measure: Questionnaire to measure nursing care self-efficacy, primaryOutcomes measure: Questionnaire to measure nurses' trust in their workplace, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Faculty of Nursing, Matrouh University, city: Mersa Matruh, zip: 002, country: Egypt, geoPoint lat: 31.3529, lon: 27.23725, hasResults: False
protocolSection identificationModule nctId: NCT06366581, orgStudyIdInfo id: HD20240307, briefTitle: Transcriptomic Analysis of Incisional Hernia Based on High-throughput Sequencing Technology, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-03-01, primaryCompletionDateStruct date: 2023-09-01, completionDateStruct date: 2024-03-01, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Fudan University, class: OTHER, descriptionModule briefSummary: This study included patients who underwent surgical treatment for incisional hernia and non-hernia conditions. Surgical specimens were collected for transcriptome sequencing to obtain the gene expression list. Then genes analyzed by Gene Ontology, protein interactions, and signaling pathway enrichment using the expression matrix., conditionsModule conditions: Incisional Hernia, conditions: Extracellular Matrix Alteration, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 36, type: ACTUAL, armsInterventionsModule interventions name: Transcriptomic analysis, outcomesModule primaryOutcomes measure: the gene expression list, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hua Dong Hospital Affiliated to Fu Dan University, city: Shanghai, country: China, geoPoint lat: 31.22222, lon: 121.45806, hasResults: False
protocolSection identificationModule nctId: NCT06366568, orgStudyIdInfo id: CRO-2022-10-PG-MER-MW-JG, briefTitle: Efficacy of a Eugenol-based Product to Improve the Quality of Toothbrushing and Relieving Gum Discomfort Areas, statusModule overallStatus: COMPLETED, startDateStruct date: 2024-02-19, primaryCompletionDateStruct date: 2024-03-06, completionDateStruct date: 2024-03-06, studyFirstPostDateStruct date: 2024-04-16, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Colgate Palmolive, class: INDUSTRY, descriptionModule briefSummary: The objective of this study is to evaluate the efficacy of a eugenol-based product in improving the quality of toothbrushing and relieving areas of gingival discomfort. This is a randomized, controlled, parallel, examiner-blind clinical trial., conditionsModule conditions: Plaque, Dental, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 86, type: ACTUAL, armsInterventionsModule interventions name: fluoride toothpaste containing 1450 ppm of MFP in a PCC base and eugenol gum product, interventions name: fluoride toothpaste containing 1450 ppm of MFP in a PCC base, outcomesModule primaryOutcomes measure: Turesky Modification of the Quigley & Hein Plaque Index, secondaryOutcomes measure: questionnaire, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Universitätsklinikum Carl Gustav Carus Technische Universität Dresden Department of Periodontology Fetscherstras, city: Dresden, zip: 01307, country: Germany, geoPoint lat: 51.05089, lon: 13.73832, hasResults: False