hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06286813, orgStudyIdInfo id: Akarakoc, briefTitle: The Effect of Almond and Extra Virgin Olive Oils on Maintaining Skin Integrity in Neonates, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-02, primaryCompletionDateStruct date: 2024-05-03, completionDateStruct date: 2024-05-30, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: Marmara University, class: OTHER, descriptionModule briefSummary: This study aimed to evaluate the effects of extra virgin olive and almond oils on maintaining skin integrity in neonates admitted to the neonatal intensive care unit.Interventional research with two parallel groups and no control group, conditionsModule conditions: Skin Care, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Interventional research with two parallel groups (almond olive group and virgin olive oil group) and no control group., primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: Plant (natural) oils, outcomesModule primaryOutcomes measure: Neonatal skin condition score, primaryOutcomes measure: Skin moisture meter(DMM):, eligibilityModule sex: ALL, minimumAge: 1 Hour, maximumAge: 72 Hours, stdAges: CHILD, contactsLocationsModule locations facility: Bakırköy Dr. Sadi Konuk Training and Research Hospital, status: RECRUITING, city: Istanbul, zip: 34854, country: Turkey, contacts name: AYŞE KARAKOÇ, role: CONTACT, phone: +905335695138, email: akarakoc@marmara.edu.tr, contacts name: Irem Zulal Topçuoglu Arslan, role: SUB_INVESTIGATOR, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06286800, orgStudyIdInfo id: PRO00036824, briefTitle: Personalized Transcranial Direct Current Stimulation in Stroke Recovery, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-14, primaryCompletionDateStruct date: 2026-03-14, completionDateStruct date: 2026-09-14, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: The Methodist Hospital Research Institute, class: OTHER, descriptionModule briefSummary: The central objective of this application is to explore the neural substrate of personalized tDCS (ptDCS) and to determine whether the paradigm for each stroke patient can predict the amount of sustained clinical improvement through increased connectivity as measured by a biomarker of plasticity., conditionsModule conditions: Stroke, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Transcranial direct current stimulation (tDCS) with OT, interventions name: Sham tDCS with OT, outcomesModule primaryOutcomes measure: fMRI functional connectivity biomarker, secondaryOutcomes measure: Wolf Motor Function Test, secondaryOutcomes measure: Fugl-Meyer assessment, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06286787, orgStudyIdInfo id: HSEARS20221110002, briefTitle: Efficacy of Mountain Craft Training at Enhancing the Resilience and Physio-psychological Well-being of Children From Low-income Families, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-11-16, primaryCompletionDateStruct date: 2024-11-01, completionDateStruct date: 2024-11-01, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: The Hong Kong Polytechnic University, class: OTHER, descriptionModule briefSummary: It is imperative to offer adequate community resources and psychosocial support, with a particular focus on enhancing resilience for children from low-income families. This study aims to determine the feasibility, acceptability, and preliminary efficacy of mountain craft training in enhancing resilience and self-esteem, reducing depressive symptoms, and improving the physical health of children from low-income families., conditionsModule conditions: Resilience, conditions: Well-being, conditions: Children, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Intervention, interventions name: Placebo, outcomesModule primaryOutcomes measure: Resilience Scale-14 (RS-14), secondaryOutcomes measure: Chinese version of the Center for Epidemiologic Studies Depression Scale for Children (CES-DC), secondaryOutcomes measure: Chinese version of Rosenberg's Self-Esteem Scale (RSES), secondaryOutcomes measure: The children's peak expiratory flow rate, eligibilityModule sex: ALL, minimumAge: 12 Years, maximumAge: 14 Years, stdAges: CHILD, contactsLocationsModule locations facility: The Asbury Methodist Social Service, status: RECRUITING, city: Hong Kong, country: China, contacts name: Chung, role: CONTACT, email: okjoyce.chung@polyu.edu.hk, geoPoint lat: 22.39407, lon: 114.13737, hasResults: False
protocolSection identificationModule nctId: NCT06286774, orgStudyIdInfo id: 2096884, briefTitle: Sleep as a Mechanism of Change in Alcohol Use, acronym: ReTRAIN, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2028-04-01, completionDateStruct date: 2028-04-01, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: University of Missouri-Columbia, class: OTHER, descriptionModule briefSummary: This project aims to evaluate improvement of insomnia as a mechanism of improvement in alcohol use outcomes., conditionsModule conditions: Insomnia, conditions: Alcohol; Harmful Use, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Subjects will be randomized to Cognitive Behavioral Therapy for Insomnia (CBT-I) or waitlist control., primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: PI Miller and study therapists will be blinded to assessment outcomes, and assessment RAs will be blinded to participant condition., whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 256, type: ESTIMATED, armsInterventionsModule interventions name: Cognitive Behavioral Therapy for Insomnia, outcomesModule primaryOutcomes measure: Insomnia Symptoms, primaryOutcomes measure: Drinking quantity, primaryOutcomes measure: Alcohol-related consequences, secondaryOutcomes measure: Treatment willingness (alcohol), secondaryOutcomes measure: Alcohol craving, secondaryOutcomes measure: Negative emotionality, secondaryOutcomes measure: Response inhibition, secondaryOutcomes measure: Working memory, secondaryOutcomes measure: Delay discounting, secondaryOutcomes measure: Alcohol to help with sleep, secondaryOutcomes measure: Heartrate variability, secondaryOutcomes measure: Dysfunctional Beliefs and Attitudes about Sleep Scale, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 49 Years, stdAges: ADULT, contactsLocationsModule locations facility: University of Missouri-Columbia, city: Columbia, state: Missouri, zip: 65212, country: United States, geoPoint lat: 38.95171, lon: -92.33407, hasResults: False
protocolSection identificationModule nctId: NCT06286761, orgStudyIdInfo id: 2100332, briefTitle: Routine Validation and Reproducibility Testing of Laboratory Measures and Research Techniques Used for Metabolism Research (VAL), acronym: VAL, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2028-03, completionDateStruct date: 2028-03, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: Bettina Mittendorfer, class: OTHER, descriptionModule briefSummary: The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research on chronic diseases (obesity, pre-diabetes and type-2 diabetes, dyslipidemia, non-alcoholic fatty liver disease, cardiovascular disease, etc.), nutrition, and metabolism (the process by which a substance is handled in your body) at the University of Missouri. As technology changes and we start to use new testing methods, it is necessary to compare results from old tests, equipment and devices and new tests, equipment, or devices and the reproducibility of these measurements to make sure we are getting accurate results. Reproducibility means performing the same test more than once to see if the same results can be achieved each time., conditionsModule conditions: Obesity, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: endothelial cell collection, outcomesModule primaryOutcomes measure: Validation and reproducibility testing for blood assays, primaryOutcomes measure: Validation and reproducibility testing for endothelial cell collection, primaryOutcomes measure: Validation and reproducibility testing for mixed meal ingestion, primaryOutcomes measure: Validation and reproducibility testing for glucose tolerance testing, primaryOutcomes measure: Validation and reproducibility testing for DEXA, primaryOutcomes measure: Validation and reproducibility testing for MRI, primaryOutcomes measure: Validation and reproducibility testing for MRS, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06286748, orgStudyIdInfo id: DeniseMafra19, briefTitle: Beetroot Extract Supplementation Associated With an Exercise Protocol for Chronic Kidney Disease Patients, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-10, primaryCompletionDateStruct date: 2024-12-10, completionDateStruct date: 2024-12-10, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: Universidade Federal Fluminense, class: OTHER, descriptionModule briefSummary: Chronic kidney disease (CKD) patients often present systemic inflammation and oxidative stress, resulting in metabolic disorders and high rates of disease-associated cardiovascular death. The literature has indicated that dietary control, the use of bioactive compounds, and the practice of regular physical exercise are essential for the prevention and management of CKD and its complications. In this context, beetroot (Beta vulgaris rubra) deserves attention as it is a source of several bioactive compounds, such as nitrate, betaine, and betalain, with beneficial effects for CKD patients, including anti-inflammatory, antioxidant effects, reduction of blood pressure, and vasodilatory action. The antioxidant and anti-inflammatory properties, in addition to their vasodilatory and antihypertensive capacity, can make supplementation of beetroot an excellent nutritional strategy to help in the treatment of CKD patients. So, this research project will bring contributions to the scientific world, providing strategies for application in clinical practice and the care of patients with CKD, on the use of beetroot associated with an exercise protocol as a non-pharmacological strategy in modulating inflammation, oxidative stress, and improved functional capacity. Furthermore, when supplemented hours before physical training, has been identified as an important factor in improving performance in these activities. Therefore, this study aims to evaluate the effects of supplementation (acute and chronic) of beetroot extract associated with an exercise protocol on complications associated with CKD., conditionsModule conditions: Chronic Kidney Diseases, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 25, type: ESTIMATED, armsInterventionsModule interventions name: Beetroot juice, interventions name: Placebo, outcomesModule primaryOutcomes measure: Change individual quality of life, primaryOutcomes measure: Change physical activity level, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06286735, orgStudyIdInfo id: DeniseMafra18, briefTitle: Effects of Cinnamomum Supplementation in Chronic Kidney Disease Patients, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-22, primaryCompletionDateStruct date: 2024-11-22, completionDateStruct date: 2024-12-22, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-03-25, sponsorCollaboratorsModule leadSponsor name: Universidade Federal Fluminense, class: OTHER, descriptionModule briefSummary: Patients with chronic kidney disease (CKD) experience many complications related to inflammation and oxidative stress that are closely related to the progression of kidney failure and increased mortality. Furthermore, these patients may have intestinal dysbiosis associated with persistent uremia, generating greater production of uremic toxins arising from the metabolism of intestinal bacteria and also helping to maintain the inflammatory process and oxidative stress. In this context, some nutritional strategies have been proposed as an adjuvant therapeutic alternative to modulate inflammation and improve the antioxidant response of patients with CKD, and even more so to modulate the intestinal microbiota. Based on the consolidated knowledge of the role of nutrients and bioactive compounds on the expression of genes related to inflammation, oxidative stress, and also the modulation of the intestinal microbiota, cinnamon, a member of the Lauraceae family, has been widely used as a spice and traditional herbal medicine for centuries and has indicated beneficial benefits in cardiovascular diseases, obesity, diabetes. The bioactive compounds in cinnamomum, such as cinnamaldehyde, cinnamic acid, and cinnamate, can attenuate oxidative stress, inflammation, hyperglycemia, intestinal dysbiosis, and dyslipidemia, which are common complications in CKD patients. Therefore, the present project proposes a longitudinal clinical trial study that aims to evaluate the effects of cinnamomum on transcription factors and inflammatory markers, oxidative stress and modulation of intestinal health in patients with CKD on hemodialysis., conditionsModule conditions: Chronic Kidney Diseases, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: cinnamomum, interventions name: Placebo, outcomesModule primaryOutcomes measure: Concentration of Nuclear factor kappa B (NF-KB), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06286696, orgStudyIdInfo id: NL84914.058.23, briefTitle: Optic Nerve Sheath Diameter in Hypertensive Emergency, acronym: OpticUS, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2026-04-01, completionDateStruct date: 2026-07-01, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: Leiden University Medical Center, class: OTHER, descriptionModule briefSummary: This prospective observational study investigates the potential of point-of-care ultrasonography of the optic nerve sheath diameter (ONSD) to rule out papilledema in patients with suspected hypertensive emergency. The primary focus is on assessing ONSD sensitivity in identifying papilledema (hypertensive retinopathy grade 4), while secondary endpoints include hypertensive retinopathy grade 3, hypertensive encephalopathy, and the need for intravenous rapid-acting medications to lower elevated blood pressure. This study aims to determine the diagnostic characteristics of this procedure for the diagnosis of hypertensive retinopathy, thus assessing its potential as a screening tool to rule out hypertensive retinopathy by the acute internal medicine doctor., conditionsModule conditions: Hypertensive Emergency, conditions: Papilledema, conditions: Hypertension, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 375, type: ESTIMATED, armsInterventionsModule interventions name: Optic Nerve Sheath Diameter, outcomesModule primaryOutcomes measure: Papilledema, secondaryOutcomes measure: Hypertensive retinopathy grade 3 & 4 combined, secondaryOutcomes measure: Hypertensive encephalopathy, secondaryOutcomes measure: Rapid acting medications administered intravenously to lower the elevated blood pressure, secondaryOutcomes measure: Presence of a bulging optic nerve disc and/or crescent sign found by ultrasonography of the optic nerve, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06286683, orgStudyIdInfo id: APHP231706, briefTitle: Impact of Early Mobilization on SAH Patients Physiological Parameters, acronym: MOBALPAH, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2027-02, completionDateStruct date: 2027-02, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Assistance Publique - Hôpitaux de Paris, class: OTHER, descriptionModule briefSummary: The aim of the study is to evaluate the physiological response to out-of-bed mobilization in patients admitted to the intensive care unit for subarachnoid hemorrhage. More specifically, the aim is to measure the impact on cerebral perfusion, lung aeration, cardiovascular and respiratory parameters., conditionsModule conditions: Subarachnoid Hemorrhage, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: lung ultrasound, interventions name: Transcranial Doppler, interventions name: near-infrared spectroscopy (NIRS), interventions name: clinical examination, outcomesModule primaryOutcomes measure: Impact on lung aeration, secondaryOutcomes measure: Impact on cerebral blood flow, secondaryOutcomes measure: Impact on cerebral tissue oxygenation, secondaryOutcomes measure: Impact on heart rate, secondaryOutcomes measure: Impact on arterial pressure, secondaryOutcomes measure: Impact on Saturation, secondaryOutcomes measure: Impact on neurological examination, secondaryOutcomes measure: Impact on patient comfort, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Adéla FOUDHAÏLI, city: Paris, zip: 75010, country: France, geoPoint lat: 48.85341, lon: 2.3488, hasResults: False
protocolSection identificationModule nctId: NCT06286657, orgStudyIdInfo id: UVienna23a, briefTitle: Xanthohumol and Viral Infections (XL), statusModule overallStatus: RECRUITING, startDateStruct date: 2023-08-01, primaryCompletionDateStruct date: 2024-04-30, completionDateStruct date: 2024-12-30, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: University of Vienna, class: OTHER, descriptionModule briefSummary: The aim of the present study is to determine if a regular oral supplementation of xanthohumol attenuate the severity of symptoms and duration of´viral infections., conditionsModule conditions: Infection Viral, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Xanthohumol, interventions name: Placebo, outcomesModule primaryOutcomes measure: Changes in severity and duration of viral infections, secondaryOutcomes measure: Changes in blood lipid levels, secondaryOutcomes measure: Changes in cognitive skills, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Vienna, status: RECRUITING, city: Vienna, zip: 1090, country: Austria, contacts name: Ina Bergheim, Prof. Dr., role: CONTACT, phone: +43-1-4277-54981, email: ina.bergheim@univie.ac.at, geoPoint lat: 48.20849, lon: 16.37208, hasResults: False
protocolSection identificationModule nctId: NCT06286644, orgStudyIdInfo id: UVienna23, briefTitle: Hop Compounds on the Immune System (VH), statusModule overallStatus: RECRUITING, startDateStruct date: 2022-05-30, primaryCompletionDateStruct date: 2024-05-30, completionDateStruct date: 2024-12-30, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: University of Vienna, class: OTHER, descriptionModule briefSummary: The aim of the present study is to determine the effect of Iso-alpha-Acids and Xanthohumol from hops on the immune response of healthy participants over a timeframe of 6 hours., conditionsModule conditions: Inflammatory Response, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 14, type: ESTIMATED, armsInterventionsModule interventions name: Xanthohumol, interventions name: Iso-alpha-Acids, interventions name: Xanthohumol + Iso-alpha-Acids, outcomesModule primaryOutcomes measure: Changes in parameters of immune response, primaryOutcomes measure: Changes in parameters of immune response, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Vienna, status: RECRUITING, city: Vienna, zip: 1090, country: Austria, contacts name: Ina Bergheim, Prof. Dr., role: CONTACT, phone: +431427754981, email: ina.bergheim@univie.ac.at, geoPoint lat: 48.20849, lon: 16.37208, hasResults: False