hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06348745, orgStudyIdInfo id: diaphragmatic ultrasound, briefTitle: Trans Thoracic Ultrasound to Assess Diaphragmatic Function in Stable COPD Versus Bronchial Asthma., statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2026-04-01, completionDateStruct date: 2026-05-01, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-08, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: * Assessment of diaphragmatic function (excursion, thickness variation, thickness ratio) in COPD and bronchial asthma patients.* Assessment of presence of correlation between diaphragmatic dysfunction and pulmonary function.* Assessment of possible association between diaphragmatic dysfunction and presence of reversibility in pulmonary function post bronchodilator., conditionsModule conditions: Diaphragm, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SCREENING, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: ultrasound, outcomesModule primaryOutcomes measure: diaphragmatic function, secondaryOutcomes measure: pulmonary function ., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06348732, orgStudyIdInfo id: biomarkers in cardiomyopathy, briefTitle: Diagnostic and Prognostic Role of Troponin and Brain Natriuretic Peptide in Pediatric Patients With Cardiomyopathy in Correlation to Echocardiography Findings, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09-01, primaryCompletionDateStruct date: 2025-09, completionDateStruct date: 2025-11, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: This study aims to assess the the role of cardiac biomarkers (troponin and ProBNP) in pediatric Patients with all types of cardiomyopathy in correlation with echocardiography findings ., conditionsModule conditions: Cardiomyopathies, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CROSSOVER, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 65, type: ESTIMATED, outcomesModule primaryOutcomes measure: Diagnostic and Prognostic Role of Troponin and Pro BNP in Pediatric Patients with Cardiomyopathy in correlation to Echocardiography findings ., eligibilityModule sex: ALL, minimumAge: 1 Month, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06348680, orgStudyIdInfo id: AmasyaU-betuluzun-004, briefTitle: The Effect of Video-assisted Episiotomy Repair Training on Anxiety and Self-efficacy Levels in Midwifery Students, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-25, primaryCompletionDateStruct date: 2024-04-05, completionDateStruct date: 2024-05-15, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Amasya University, class: OTHER, descriptionModule briefSummary: The goal of midwifery undergraduate education is; To provide students with basic professional knowledge, skills and attitudes in cognitive, affective and psychomotor dimensions. Various practices are used to provide students with midwifery skills. Case studies, maintenance processes, laboratory applications, field studies, simulation application and video monitoring are some of these applications. Each of these approaches, which are especially preferred in applied courses, has an important place in increasing students' self-efficacy and reducing their anxiety. Episiotomy is one of the obstetric interventions that negatively affects the self-efficacy of midwifery students and causes anxiety. Midwives are responsible for performing and caring for episiotomy. In many countries, episiotomy repair training is given to midwifery students using sponges or models. However, today the use of calf tongue, which is very similar to perineal tissue, has become widespread. There are a limited number of studies in the literature using calf tongue simulation. These studies suggested that the practice improved the skills of midwifery students. No study has been found in the literature using video-assisted episiotomy repair training., conditionsModule conditions: Episiotomy Wound, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 31, type: ESTIMATED, armsInterventionsModule interventions name: Video assisted episiotomy repair training, outcomesModule primaryOutcomes measure: State Anxiety Scale, primaryOutcomes measure: Episiotomy Skills Self-Efficacy Scale, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06348667, orgStudyIdInfo id: 3184794, briefTitle: Effects of a Short- and Long-term 'Blackboard' Intervention on Ankle Stability in Older Adults, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-07, primaryCompletionDateStruct date: 2024-06-10, completionDateStruct date: 2024-06-10, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: University of Valencia, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to assess the effectiveness of adding specific Blackboard Training (BB) exercises to conventional physiotherapy in improving foot and ankle parameters essential for fall prevention among older adults.The main questions it aims to answer are:1. Can the addition of BB exercises improve ankle dorsiflexion mobility?2. Can the addition of BB exercises enhance single-leg stability and control of mediolateral displacement of the center of pressure?Participants will be divided into control and intervention groups. Both groups will receive their usual conventional physiotherapy exercises. The intervention group will undergo a 5-week program comprising 10 sessions of BB exercises targeting ankle mobility and balance.Participants will be asked to:* Perform 3 sets of 15 repetitions for assisted ankle dorsiflexion mobility.* Engage in 5 rounds of 40-second balance exercises using the BB.Researchers will compare the intervention group's outcomes with those of the control group to determine the effectiveness of adding BB exercises in improving foot and ankle parameters related to fall prevention., conditionsModule conditions: Fall, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: DOUBLE, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 32, type: ESTIMATED, armsInterventionsModule interventions name: Specific ankle stability exercises, interventions name: Conventional physiotherapy exercises program, outcomesModule primaryOutcomes measure: Foot and ankle pain, primaryOutcomes measure: Foot and ankle strength, primaryOutcomes measure: Foot and ankle ROM, primaryOutcomes measure: Ankle dorsiflexion under load, primaryOutcomes measure: Center of pressures variations (anteroposterior and mediolateral center of pressure displacement, velocity, and total surface), primaryOutcomes measure: Monopodal stability, primaryOutcomes measure: Functional stability, eligibilityModule sex: ALL, minimumAge: 75 Years, maximumAge: 95 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Rodrigo Martin-San Agustin, status: RECRUITING, city: Valencia, country: Spain, contacts name: Rodrigo Martin-San Agustin, role: CONTACT, phone: +34 963 983 853, email: rodrigo.martin@uv.es, geoPoint lat: 39.46975, lon: -0.37739, hasResults: False
protocolSection identificationModule nctId: NCT06348654, orgStudyIdInfo id: 6392, briefTitle: New Digital Person-based Care Model in Patients With HER2-negative Advanced Breast Cancer, acronym: InPERSON, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-30, primaryCompletionDateStruct date: 2024-12-01, completionDateStruct date: 2025-01-01, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, class: OTHER, descriptionModule briefSummary: The goal of the InPerson study is to employ all resources in a digital listening platform to benefit the quality of life of patients (QoL) with advanced HER2-negative breast cancer.The care pathway of patients with this type of disease represents an optimal setting for the implementation of an innovative narrative medicine pathway that, aided by integrative therapies, aims to support and accompain them in their treatment journey with a continuum of care. Moreover, the narrative medicine platform will implement the actual "static" way to define QoL with the classic Patient-Reported Outcomes (PROs) questionnaires, that reflect the patient status at a certain time point and not as a dinamic entity. It is on the basis of these assumptions that the present application project on the use of the DNMLAB digital narrative diary in the oncology department of the Fondazione Policlinico Gemelli was born., conditionsModule conditions: Breast Cancer, conditions: Narrative Medicine, conditions: HER2-negative Breast Cancer, conditions: Patient Satisfaction, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: RETROSPECTIVE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: introduction of digital listening may improve the quality of life of patients withe breast cancer, outcomesModule primaryOutcomes measure: Standardized quality-of-life measurement, primaryOutcomes measure: Perceived quality of life, primaryOutcomes measure: Personalization of the care pathway, primaryOutcomes measure: Quality of the patient-physician relationship., secondaryOutcomes measure: Interaction between multidisciplinary teams, secondaryOutcomes measure: Patient involvement and compliance in the care pathway, secondaryOutcomes measure: lifestyles best suited to positively affect quality of life, secondaryOutcomes measure: Awareness of disease condition, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06348628, orgStudyIdInfo id: P/38/04/2021, briefTitle: Motivational Interviewing in the Management of Non Alcoholic Fatty Liver Disease, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2022-05-31, primaryCompletionDateStruct date: 2025-01, completionDateStruct date: 2025-07, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Madunil Anuk Niriella, class: OTHER, descriptionModule briefSummary: The goal of this study is to assess if motivational counselling works to reduce the weight in participants with Non Alcoholic Fatty Liver Disease (NAFLD)., conditionsModule conditions: Non-Alcoholic Fatty Liver Disease, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 231, type: ACTUAL, armsInterventionsModule interventions name: Motivational Interview, interventions name: Placebo, outcomesModule primaryOutcomes measure: Change in weight after 1 year compared to baseline, primaryOutcomes measure: Change in Aspartate aminotransferase (AST) level and Alanine aminotransferase (ALT) level after 1 year compared to baseline, primaryOutcomes measure: Change in platelet count after 1 year compared to baseline, primaryOutcomes measure: Change in waist circumference and hip circumference after 1 year compared to baseline, primaryOutcomes measure: Change in total fat percentage and visceral fat percentage after 1 year compared to baseline, secondaryOutcomes measure: Change in motivation for weight loss after 1 year compared to baseline, secondaryOutcomes measure: Change in depression, anxiety and stress after 1 year compared to baseline, secondaryOutcomes measure: Change in quality of life after 1 year compared to baseline, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Faculty of Medicine, University of Kelaniya, city: Ragama, state: Western Province, zip: 11010, country: Sri Lanka, geoPoint lat: 7.0292, lon: 79.917, hasResults: False
protocolSection identificationModule nctId: NCT06348589, orgStudyIdInfo id: 2023-05959-01, briefTitle: Orthostatic Hypotension and Blood Pressure Variability in Persons Undergoing Hemodialysis, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2024-09, completionDateStruct date: 2024-09, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Vrinnevi Hospital, class: OTHER, collaborators name: Linkoeping University, descriptionModule briefSummary: High blood pressure is a risk factor for end-stage renal disease and is common in patients undergoing maintenance hemodialysis. Intradialytic hypotension is associated with an adverse prognosis. More knowledge is needed to identify patients at high risk for intradialytic hypotension and dialysis-associated hypotensive episodes. The aim of this observational single-center pilot study is to evaluate whether point-of-care ultrasound measurements may predict intradialytic hypotension and orthostatic blood pressure falls, in patients with chronic kidney disease who undergo maintenance hemodialysis., conditionsModule conditions: Chronic Kidney Disease Requiring Chronic Dialysis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 50, type: ESTIMATED, outcomesModule primaryOutcomes measure: Intra-dialytic systolic blood pressure fall of 20 mmHg or larger, primaryOutcomes measure: Post-dialytic orthostatic systolic blood pressure fall of 20 mmHg or larger, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06348576, orgStudyIdInfo id: AD-209P3, briefTitle: Phase III Study to Evaluate the Efficacy and Safety of AD-209, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-02, completionDateStruct date: 2025-02, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Addpharma Inc., class: INDUSTRY, descriptionModule briefSummary: The purpose of this study is to evaluate the efficacy and safety of AD-209, conditionsModule conditions: Hypertension,Essential, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 280, type: ESTIMATED, armsInterventionsModule interventions name: AD-209, interventions name: AD-2091, interventions name: AD-209 Placebo, interventions name: AD-2091 Placebo, outcomesModule primaryOutcomes measure: Change rate of MSSBP, eligibilityModule sex: ALL, minimumAge: 19 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Korea University Guro Hospital, city: Seoul, country: Korea, Republic of, contacts name: Chang Gyu Park, M.D., Ph.D, role: CONTACT, contacts name: Chang Gyu Park, M.D., Ph.D, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 37.566, lon: 126.9784, hasResults: False
protocolSection identificationModule nctId: NCT06348563, orgStudyIdInfo id: 7437787981, briefTitle: AGED Diagnostics Liver Disease Assessment, acronym: AGEDDX, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-15, primaryCompletionDateStruct date: 2025-05-15, completionDateStruct date: 2025-09-15, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Active Genomes Expressed Diagnostics, Corp, class: INDUSTRY, collaborators name: Arizona Clinical Trials, collaborators name: Walter Reed National Military Medical Center, descriptionModule briefSummary: Continue development of previously established methods to further validate candidate biomarkers that can discriminate steatosis from NASH and separately stage fibrosis from blood. The first assessment is to conduct test method verification to expand sample size to several hundred samples through whole genome sequencing methods. The second assessment is focused on biomarker validation by comparing targeted sequencing from patient plasma. Several sub- assessments will be conducted to support overall biomarker development efforts., conditionsModule conditions: NASH With Fibrosis, conditions: NAFLD, conditions: Healthy, designModule studyType: INTERVENTIONAL, phases: EARLY_PHASE1, designInfo allocation: NON_RANDOMIZED, interventionModel: SINGLE_GROUP, primaryPurpose: DIAGNOSTIC, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 400, type: ESTIMATED, armsInterventionsModule interventions name: AGED Multiple Target Assay in Healthy Controls, interventions name: AGED Multiple Target Assay in NAFLD Participants, interventions name: AGED Multiple Target Assay in Fibrosis Participants, outcomesModule primaryOutcomes measure: Test Method Verification, Whole genome bisulfite sequencing assessment for liver tissue and plasma, secondaryOutcomes measure: Biomarker Validation, Targeted Epigenetic Sequencing Assessment, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: AGED Diagnostics, city: Bethesda, state: Maryland, zip: 20002, country: United States, contacts name: Rachel Zayas, role: CONTACT, phone: 617-777-7971, email: rachel@ageddiagnostics.com, geoPoint lat: 38.98067, lon: -77.10026, hasResults: False
protocolSection identificationModule nctId: NCT06348550, orgStudyIdInfo id: BFMKP 01, briefTitle: Effect of the Association of Berberine Fitosoma® and Monacolin K MonaKoPure® on Glyco-metabolic Parameters in Dysglycemic and Dyslipidemic Patients., statusModule overallStatus: RECRUITING, startDateStruct date: 2023-11-30, primaryCompletionDateStruct date: 2024-07, completionDateStruct date: 2024-09, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: University of Pavia, class: OTHER, collaborators name: Foundation IRCCS San Matteo Hospital, descriptionModule briefSummary: The objective of this study is to evaluate the effectiveness of the association Berberina Fitosoma® and monacolin K MonaKoPure® (Berberol® K supplement) compared to placebo on glucidic and lipid parameters in subjects with fasting blood glucose (FPG) values between 100 and 125 mg/dl and with total cholesterol (TC) values ≥ 200 mg/dl., conditionsModule conditions: Dyslipidemias, conditions: Dysglycemia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: Berberol® K, interventions name: Placebo, outcomesModule primaryOutcomes measure: Variation of LDL cholesterol, secondaryOutcomes measure: Variation of lipid profile, secondaryOutcomes measure: Change in glycemic status, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: IRCCS Policlinico S. Matteo Foundation, status: RECRUITING, city: Pavia, zip: 27100, country: Italy, contacts name: Giuseppe Derosa, MD, PhD, role: CONTACT, email: giuseppe.derosa@unipv.it, contacts name: Pamela Maffioli, MD, role: CONTACT, email: p.maffioli@smatteo.pv.it, contacts name: Giuseppe Derosa, MD, PhD, role: PRINCIPAL_INVESTIGATOR, contacts name: Pamela Maffioli, MD, role: SUB_INVESTIGATOR, geoPoint lat: 45.19205, lon: 9.15917, hasResults: False
protocolSection identificationModule nctId: NCT06348537, orgStudyIdInfo id: Polyphenol-Fibromyalgia, briefTitle: Effects of Olive Polyphenols in Fibromyalgia Patients, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-01-20, primaryCompletionDateStruct date: 2021-04-01, completionDateStruct date: 2023-09-01, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Universidad de Granada, class: OTHER, collaborators name: Solvitae Medical, S.L, collaborators name: University of Jaén, descriptionModule briefSummary: To study the effects of a nutritional intervention with an olive (poly)phenol preparation in female patients with FM., conditionsModule conditions: Fibromyalgia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 40, type: ACTUAL, armsInterventionsModule interventions name: Olive Polyphenols, interventions name: Placebo, outcomesModule primaryOutcomes measure: Plasma proteome, primaryOutcomes measure: Lipid peroxidation, secondaryOutcomes measure: Aldolase, secondaryOutcomes measure: C-reactive protein (CRP), secondaryOutcomes measure: Impact of fibromyalgia, secondaryOutcomes measure: Quality of Life, secondaryOutcomes measure: Red blood cells, secondaryOutcomes measure: Haemoglobin, secondaryOutcomes measure: Fibrinogen, secondaryOutcomes measure: Total cholesterol, secondaryOutcomes measure: Cholesterol ratio, secondaryOutcomes measure: LDL cholesterol, secondaryOutcomes measure: Cortisol, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Jaén, city: Jaén, zip: 23071, country: Spain, geoPoint lat: 37.76922, lon: -3.79028, hasResults: False