hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06346808, orgStudyIdInfo id: PDAC-OV, briefTitle: Oncolytic Virus Plus Anti-PD1 and Chemotherapy as Preoperative Therapy for Patients With BRPC/LAPC, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2026-05-01, completionDateStruct date: 2027-05-01, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Sichuan University, class: OTHER, descriptionModule briefSummary: The aim of this single center, single arm and prospective study is to explore the safety and efficacy of Oncolytic virus Plus Anti-PD1 and Chemotherapy as Preoperative therapy for Patients with Borderline Resectable and Locally Advanced Pancreatic Cancer, conditionsModule conditions: Pancreatic Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: Oncolytic virus Plus Anti-PD1 and Chemotherapy, outcomesModule primaryOutcomes measure: Incidence of Treatment-Related Adverse Events [Safety and Tolerability], secondaryOutcomes measure: R0 resection rate, secondaryOutcomes measure: ORR, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: West China Hospital, Sichuan University, city: Chengdu, state: Sichuan, zip: 610000, country: China, contacts name: Zhong Wu, MD, role: CONTACT, geoPoint lat: 30.66667, lon: 104.06667, hasResults: False
protocolSection identificationModule nctId: NCT06346795, orgStudyIdInfo id: SelcukC, briefTitle: Class II Restorations With High-Filled Flowable Composites, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2024-12-01, completionDateStruct date: 2025-06-01, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-25, sponsorCollaboratorsModule leadSponsor name: Selcuk University, class: OTHER, descriptionModule briefSummary: In the study, Class II restorations will be performed with G-aenial Universal Injectable (GC/ Tokyo, Japan), Grandio Flow (VOCO/ Germany), and Clearfil Majesty Flow (Kuraray/ Japan) composites will evaluated. Restorations will be assessed according to modified USPHS criteria in 1st week, 6th months, and 12th months from the placement date. The Chi-square test will used for statistical analysis of the difference between the groups, and the Cochran Q test will used for the significance of the difference between time-dependent changes within each group (p\<0.05)., conditionsModule conditions: Dental Caries, conditions: Class II Dental Caries, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: High-filling flowable dental composite, outcomesModule primaryOutcomes measure: Retention, primaryOutcomes measure: Color match, primaryOutcomes measure: Marginal discoloration, primaryOutcomes measure: Marginal adaptation, primaryOutcomes measure: Secondary caries, primaryOutcomes measure: Surface texture, primaryOutcomes measure: Anatomical form, primaryOutcomes measure: Postoperative sensitivity, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule locations facility: Selcuk University, Faculty of Dentistry, Restorative Dentistry Department, city: Konya, country: Turkey, geoPoint lat: 37.87135, lon: 32.48464, hasResults: False
protocolSection identificationModule nctId: NCT06346782, orgStudyIdInfo id: IRB00370545, briefTitle: Feasibility and Acceptability of Internet-based Parent-child Interaction Therapy (I-PCIT) in Pediatric Cancer, acronym: I-PCIT, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-19, primaryCompletionDateStruct date: 2028-08-01, completionDateStruct date: 2028-08-01, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Johns Hopkins All Children's Hospital, class: OTHER, descriptionModule briefSummary: This study is being done to learn whether a telehealth intervention called "Internet-Based Parent Child Interaction Therapy," or I-PCIT," can help parents improve the child's behavior if the child currently or previously went through cancer treatment.Parents who choose to be in this study will complete a survey to help researchers figure out if the parent is eligible for the larger study. If a parent is eligible for the larger study and chooses to participate, if so, the participants will be randomly assigned to either receive the I-PCIT intervention now or to be on a waitlist and begin I-PCIT in 5-6 months. The whole study consists of completing I-PCIT sessions with a clinician and completing 3-4 follow-up surveys after the initial screener survey., conditionsModule conditions: Pediatric Cancer, conditions: Oncology, conditions: Disruptive Behavior, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: This is a pilot feasibility trial. We are using a 2:1 (intervention: waitlist control) randomized controlled design., primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 300, type: ESTIMATED, armsInterventionsModule interventions name: Internet-Based Parent-Child Interaction Therapy, outcomesModule primaryOutcomes measure: I-PCIT Feasibility as assessed by intervention completion, primaryOutcomes measure: I-PCIT Acceptability as assessed by the Treatment Evaluation Inventory Short form, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Johns Hopkins All Children's Hospital, status: RECRUITING, city: Saint Petersburg, state: Florida, zip: 33701, country: United States, contacts name: Melissa Faith, Ph.D., role: CONTACT, phone: 727-295-8477, email: mfaith1@jhmi.edu, geoPoint lat: 27.77086, lon: -82.67927, hasResults: False
protocolSection identificationModule nctId: NCT06346769, orgStudyIdInfo id: SelcukB, briefTitle: Composite Restorations Performed by Placing Polyethylene Fiber, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2024-10-15, completionDateStruct date: 2025-04-15, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Selcuk University, class: OTHER, descriptionModule briefSummary: This study aimed to evaluate the 12-month clinical performance of direct composite restorations by placing polyethylene fibers in different directions in endodontically treated posterior teeth. In this clinical study, Clearfil SE Bond (Kuraray/Japan) adhesive system, G-aenial Universal Injectable (GC/Tokyo, Japan), G-aenial A'chord (GC/Tokyo, Japan) composites, and polyethylene fiber (Ribbond, USA) were used. In the restoration of the teeth included in the study, polyethylene fiber was placed in different directions according to the amount of remaining tooth tissue and cavity preparation. The restorations were divided into three groups according to the direction of fiber placement ('O' shape, mesiodistal I shape, buccolingual I shape) (n=12). Restorations were evaluated according to modified USPHS criteria in 1st week and 6th months from the placement date. The Chi-square test was used for statistical analysis of the difference between the groups, and the Cochran Q test was used for the significance of the difference between time-dependent changes within each group (p\<0.05)., conditionsModule conditions: Endodontically Treated Teeth, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 68, type: ACTUAL, armsInterventionsModule interventions name: Polyethylene Fiber, outcomesModule primaryOutcomes measure: Retention, primaryOutcomes measure: Color match, primaryOutcomes measure: Marginal Discoloration, primaryOutcomes measure: Marginal adaptation, primaryOutcomes measure: Secondary caries, primaryOutcomes measure: Surface texture, primaryOutcomes measure: Anatomical form, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule locations facility: Selcuk University, Faculty of Dentistry, Restorative Dentistry Department, city: Konya, country: Turkey, geoPoint lat: 37.87135, lon: 32.48464, locations facility: Selcuk University, Faculty of Dentistry, city: Konya, country: Turkey, geoPoint lat: 37.87135, lon: 32.48464, hasResults: False
protocolSection identificationModule nctId: NCT06346756, orgStudyIdInfo id: SelcukA, briefTitle: Clinical Evaluation of Class II Restorations, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-01-01, primaryCompletionDateStruct date: 2023-07-01, completionDateStruct date: 2023-07-15, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Selcuk University, class: OTHER, descriptionModule briefSummary: This study aims to evaluate the one-year clinical performance of Class II restorations made with high-filling injectable and condensable universal composite resins.The study included 62 patients and 147 restorations. It used G-aenial Universal Injectable (GCI), G-aenial A'CHORD (GCA), Tetric Prime (TP), Filtek Ultimate (FU) composites, and the Clearfil SE Bond adhesive system. GCI only in premolar teeth; GCA, TP, and FU have been used to restore premolar and molar teeth. Restorations were evaluated and scored according to modified USPHS criteria at seven days, six months, and one year. Chi-square and Cochran Q tests were used for statistical analysis (p\<0.05)., conditionsModule conditions: Dental Caries, conditions: Dental Caries Class II, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 62, type: ACTUAL, armsInterventionsModule interventions name: Treatment of dental caries., outcomesModule primaryOutcomes measure: Retention, secondaryOutcomes measure: color match, secondaryOutcomes measure: marginal adaptation, secondaryOutcomes measure: marginal discoloration, secondaryOutcomes measure: surface texture, secondaryOutcomes measure: anatomical form, secondaryOutcomes measure: secondary caries, secondaryOutcomes measure: postoperative sensitivity, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule locations facility: Selcuk University, Faculty of Dentistry, city: Konya, country: Turkey, geoPoint lat: 37.87135, lon: 32.48464, hasResults: False
protocolSection identificationModule nctId: NCT06346730, orgStudyIdInfo id: 142-18, briefTitle: The Effect of Virtual Reality Application on Anxiety and Patient Satisfaction During Intrauterine Insemination (IUI), acronym: (IUI), statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-15, primaryCompletionDateStruct date: 2024-08-30, completionDateStruct date: 2024-09-30, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Suleyman Demirel University, class: OTHER, descriptionModule briefSummary: This study will conduct as a randomized pretest-posttest study to examine the effect of virtual reality glasses (VRG) application during the IUI procedure on anxiety and patient satisfaction. The population of the research will consist of women who were treated with assisted reproductive techniques and underwent IUI at the infertility polyclinic of Ministry of Health Adana City Training and Research Hospital between May and December 2024 and who meet the research criteria. The research sample was calculated as a total of 90 people (at least 45 people in each group) using the power program. Data; Personal Information Form, Visual Assessment Scale (VAS), State Trait Anxiety Inventory (STAI) and Patient's Perception of Nursing Care Scale will be collected from women who agree to participate in the research. Virtual reality glasses will be applied to the intervention group., conditionsModule conditions: Virtual Reality, conditions: Anxiety, conditions: Patient Satisfaction, conditions: Intrauterine Insemination (IUI), designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The sample will divide into intervention and control groups, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 90, type: ESTIMATED, armsInterventionsModule interventions name: Virtual reality glasses to intervention group, outcomesModule primaryOutcomes measure: State Trait Anxiety Inventory (STAI), primaryOutcomes measure: Patient's Perception of Nursing Care Scale, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06346717, orgStudyIdInfo id: SINOPU-elif 2, briefTitle: Mobile Application Based Care for Total Knee Prosthesis Patients, acronym: KneeMobilApp, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-27, primaryCompletionDateStruct date: 2025-03-30, completionDateStruct date: 2025-03-30, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Sinop University, class: OTHER, descriptionModule briefSummary: Total knee prosthesis (TKP); It is a surgical treatment used in the management of functional limitations and severe pain occurring on the degenerated joint surface as a result of rheumatoid arthritis, osteoarthritis, posttraumatic arthritis and other nonspecific arthritis. Nursing care is of great importance in the success of TKP surgery. Reducing pain, preventing complications, increasing self-care ability, and improving the quality of life by improving postoperative knee functions are the main goals of postoperative nursing care. In order to achieve these goals, patients and their relatives need to receive training on home care in the post-operative period before discharge. With the increasing use of mobile technologies in daily life and the increasing adoption of e-health, the opportunity for people to improve their self-management skills through e-health is increasing. Mobile Health (m-Health) provides convenience in many areas such as educating the public, warning about potential diseases and disease risks, and communicating with messages, notifications and video when necessary. It also affects the way nursing services are delivered and provides great benefits in the delivery of nursing services. For all these reasons, it was aimed to examine the effect of mobile application-supported care given to patients with total knee prosthesis on functional status and self-care ability., conditionsModule conditions: Knee Prosthesis, conditions: Mobile Application, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: "Knee Prosthesis-M" mobile application service, outcomesModule primaryOutcomes measure: Knee Injury and Osteoarthritis Outcome Score = KOOS, secondaryOutcomes measure: Exercise of Self-Care Agency=ESCA, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Elif ALTINKAYNAK SARAL, status: RECRUITING, city: Merkez, state: Osmaniye Köyü, zip: 5700, country: Turkey, contacts name: ELİF ALTINKAYNAK SARAL, PhD, role: CONTACT, phone: 05436071986, email: ealtinkynk@hotmail.com, contacts name: Sonay GÖKTAŞ, PhD, role: CONTACT, phone: 05324567776, email: sonay.goktas@sbu.edu.tr, hasResults: False
protocolSection identificationModule nctId: NCT06346704, orgStudyIdInfo id: PR5030-66, briefTitle: Prospective Longitudinal Monocentric Study to Evaluate the Syde® Digital Endpoint in Patients With Multiple Sclerosis, acronym: NHS-MS-EGYPT, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-25, primaryCompletionDateStruct date: 2026-11-30, completionDateStruct date: 2026-11-30, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: SYSNAV, class: INDUSTRY, descriptionModule briefSummary: The study aims to assess the validity of real-world activity monitoring by the Syde® wearable device in subjects with multiple slclerosis. The Syde® collected data will be compared to on-site conventional clinical endpoints for MS pathology (EDSS, FSS and T25FWT). Subjects with multiple sclerosis will be assessed every 6 months for 2 years., conditionsModule conditions: Multiple Sclerosis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Digital HealthTechnology, outcomesModule primaryOutcomes measure: Longitudinal change of 95th centile of stride velocity, secondaryOutcomes measure: Correlation of the Syde® variables with the clinical assessments EDSS, FSS and T25FWT, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06346691, orgStudyIdInfo id: MTU-EC-IM-0-235/66, briefTitle: Bronchodilator Effect of Oral Doxofylline and Procaterol in Chronic Obstructive Pulmonary Disease, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-16, primaryCompletionDateStruct date: 2024-09-30, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Thammasat University, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to determine if doxofylline and procaterol are effective in treating patients with stable chronic obstructive pulmonary disease (COPD). It will also assess the safety of both drugs.The main questions it aims to answer are:* Does doxofylline demonstrate a comparable bronchodilator effect to procaterol in COPD participants?* What medical problems do participants experience when taking doxofylline and procaterol?", conditionsModule conditions: COPD, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: Crossover randomized controlled trial, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: Doxofylline, interventions name: Procaterol, outcomesModule primaryOutcomes measure: Forced expiratory volume in 1 second (FEV1), primaryOutcomes measure: Forced vital capacity (FVC), primaryOutcomes measure: Forced expiratory flow at 25-75% of FVC (FEF25-75), secondaryOutcomes measure: modified Medical Research Council (mMRC) score, secondaryOutcomes measure: COPD Assessment Test (CAT), eligibilityModule sex: ALL, minimumAge: 40 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06346678, orgStudyIdInfo id: MTU-EC-IM-0-016/67, briefTitle: Accuracy of Accuhaler Tester, Ellipta Tester and Turbutester in Patients With Chronic Obstructive Pulmonary Disease, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-16, primaryCompletionDateStruct date: 2024-08-31, completionDateStruct date: 2024-10-31, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Thammasat University, class: OTHER, descriptionModule briefSummary: The goal of this observational study is to investigate the accuracy of Accuhaler tester, Ellipta tester and Turbutester in patients with chronic obstructive pulmonary disease (COPD). The main question it aims to answer is:• Do Accuhaler tester, Ellipta tester, and Turbutester demonstrate comparable accuracy to the In-check DIAL for assessing inspiratory inhalation force in COPD patients?, conditionsModule conditions: Chronic Obstructive Pulmonary Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Accuhaler tester, outcomesModule primaryOutcomes measure: Accuracy of Accuhaler tester, primaryOutcomes measure: Accuracy of Ellipta tester, primaryOutcomes measure: Accuracy of Turbutester, secondaryOutcomes measure: Prevalence of suboptimal peak inspiratory flow rate, secondaryOutcomes measure: Prevalence of insufficient peak inspiratory flow rate, eligibilityModule sex: ALL, minimumAge: 40 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06346665, orgStudyIdInfo id: DZIF Tx-Cohort, briefTitle: The Transplant Cohort of the German Center for Infection Research, statusModule overallStatus: RECRUITING, startDateStruct date: 2016-01, primaryCompletionDateStruct date: 2025-12, completionDateStruct date: 2030-12, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Technical University of Munich, class: OTHER, collaborators name: Hannover Medical School, collaborators name: University Hospital Heidelberg, collaborators name: Universität Tübingen, collaborators name: Klinikum der Universität München, collaborators name: Max von Pettenkofer-Institut München, collaborators name: Nierenzentrum Heidelberg, collaborators name: Helmholtz Centre for Infection Research, descriptionModule briefSummary: Medical data and biological samples obtained from transplant patients are collected and managed across Germany with the help of the DZIF Transplant Cohort. The data and samples form the basis of scientific studies which investigate the connections between numerous factors influencing an organ's susceptibility to infection and organ function., conditionsModule conditions: Infections, conditions: Transplant Complication, conditions: Transplant Failure, conditions: Immunosuppression, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 3000, type: ESTIMATED, outcomesModule primaryOutcomes measure: Realisation of studies that focus on the the medical needs of transplant patients, particularly with regard to their susceptibility to infection, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Technische Universität München, status: RECRUITING, city: München, country: Germany, contacts name: Daniela Schindle, Dr., role: CONTACT, geoPoint lat: 48.13743, lon: 11.57549, hasResults: False