protocolSection identificationModule nctId: NCT06273449, orgStudyIdInfo id: 385/2023, briefTitle: A Smart Digital Workflow Towards High Precision and Through-Put Production for Removable Partial Dentures, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-12-29, primaryCompletionDateStruct date: 2024-08-30, completionDateStruct date: 2024-08-30, studyFirstPostDateStruct date: 2024-02-22, lastUpdatePostDateStruct date: 2024-02-22, sponsorCollaboratorsModule leadSponsor name: National Dental Centre, Singapore, class: OTHER, collaborators name: National Medical Research Council (NMRC), Singapore, descriptionModule briefSummary: Tooth loss is a major chronic problem in dentistry and edentulous elderly endures poorer quality of life worldwide. Removable partial dentures (RPDs) are the most widely accepted and cost-effective treatment for patients to restore oral functions. RPDs contain three components including the metal framework, denture base and acrylic teeth. Conventionally, RPD fabrication involves tedious clinical and dental laboratory procedures and is time consuming, labour-intensive, and often imprecise, therefore incapable of meeting the growing demands of RPD by an ageing population. The challenges to achieve a high quality and high-throughput RPD service lie in three aspects: 1) accuracy in capturing oral profile; 2) immediate oral information analysis and device design, and 3) automation in production., conditionsModule conditions: Partial-edentulism, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: SEQUENTIAL, interventionModelDescription: 1. Conventional: The Standard of Care (SOC) workflow, which will act as a baseline compared to the other 2 groups.2. Partial digital workflow: Adopts the same teeth profile capture method, where a physical impression of teeth profile is taken from the subject. However, instead of using physical wax pattern on the stone model for design, the stone model is scanned and, on the scan, the design is performed digitally. For fabrication of RPD, instead of using lost wax casting, the digital design is used for additive manufacturing.3. SmartRPD digital workflow Adopts a different teeth profile capture method by using the intraoral scanner to digitally scan and save the subject's teeth profile. From the intraoral scan, a digital model of the subject's teeth profile is created but on the digital model instead, the design of RPD is digitally performed. The digital design is used for additive manufacturing., primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 141, type: ESTIMATED, armsInterventionsModule interventions name: Group 3 - 3D Printed Removable Partial Denture, interventions name: Group 2 - 3D Printed Removable Partial Denture, outcomesModule primaryOutcomes measure: Evaluation of Precision in Fabricated Metal Frameworks Across Three Workflows, primaryOutcomes measure: Comparison of Patient Satisfaction with RPD Prostheses Fabricated Using Three Workflows, primaryOutcomes measure: Comparison of Fabrication Cost and Time Across Three Workflows, eligibilityModule sex: ALL, minimumAge: 21 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: National Dental Centre Singapore, status: RECRUITING, city: Singapore, zip: 168938, country: Singapore, contacts name: Hazel Goh Si Ying, role: CONTACT, phone: 63248754, email: goh.si.ying@ndcs.com.sg, contacts name: Zi Ying Phang, role: PRINCIPAL_INVESTIGATOR, contacts name: Khim Hean Teoh, role: SUB_INVESTIGATOR, contacts name: Janice Tan Zhi Hui, role: SUB_INVESTIGATOR, geoPoint lat: 1.28967, lon: 103.85007, hasResults: False