hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06295263, orgStudyIdInfo id: KYLL-202203-028-1, briefTitle: Application of AI Technology for the Diagnosis and Treatment of Geriatric Diseases, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-03-01, primaryCompletionDateStruct date: 2026-06-28, completionDateStruct date: 2026-06-29, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: Qilu Hospital of Shandong University, class: OTHER, collaborators name: Shandong University, descriptionModule briefSummary: 1) Characteristics of handwriting, gait, speech, eye movements, biological samples (blood, urine, stool, saliva, etc.), images, EEG, and other relevant markers in patients with Alzheimer's disease.(2) Characteristics of handwriting, gait, language, eye movement, biological samples (blood, urine, stool, saliva, etc.), imaging, EEG, and other relevant markers in patients with Parkinson's disease.(3) Characteristics of handwriting, gait, language, eye movement, biological samples (blood, urine, stool, saliva, etc.), images, EEG, and other relevant markers in patients with other neurological disorders.(4) Characteristics of handwriting, gait, language, eye movement, biological samples (blood, urine, stool, saliva, etc.), images, EEG and other relevant markers in elderly patients., conditionsModule conditions: Parkinson Disease, conditions: Alzheimer Disease, conditions: Nervous System Diseases, conditions: Geriatric Diseases, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: RETROSPECTIVE, enrollmentInfo count: 460, type: ESTIMATED, armsInterventionsModule interventions name: Handwriting, gait, speech, eye movements, biological samples (blood, urine, stool, saliva, etc.), images, EEG, and other relevant markers, outcomesModule primaryOutcomes measure: Handwriting, primaryOutcomes measure: gait, primaryOutcomes measure: speech, primaryOutcomes measure: eye movements, primaryOutcomes measure: biological samples (blood, urine, stool, saliva, etc.), primaryOutcomes measure: images, primaryOutcomes measure: EEG, primaryOutcomes measure: other relevant markers, eligibilityModule sex: ALL, minimumAge: 8 Years, maximumAge: 100 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Qilu Hospital of Shandong University, status: RECRUITING, city: Jinan, state: Shandong, zip: 250012, country: China, contacts name: Wenjing Jiang, role: CONTACT, phone: 18560082210, email: jiangwenjing@qiluhospital.com, geoPoint lat: 36.66833, lon: 116.99722, hasResults: False
protocolSection identificationModule nctId: NCT06295237, orgStudyIdInfo id: i-Sync, briefTitle: Automatic Adjustment for Asynchronies During Mechanical Ventilation, acronym: i-Sync, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-15, primaryCompletionDateStruct date: 2025-02-15, completionDateStruct date: 2025-07-01, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Hospital San Carlos, Madrid, class: OTHER, collaborators name: Fundación de Investigación Biomédica - Hospital Universitario de La Princesa, descriptionModule briefSummary: Asynchronies between the patient and the artificial ventilator are a frequent problem. They may cause altered sleep, ventilator-induced lung injury, prolong length of ICU stay, cause neuro-psycologic complications and increase mortality. Although reducing their incidence through ventilator setting adjustments is possible, they frequently go undetected and it also requires that attendings remain at the bedside to repeatedly modify ventilator parameters. Ventilator systems may detect and automatically adjust parameters of mechanical ventilation. This would avoid delays in detection and adjustment if the intensivist is not immediately available. The investigators intend to study an automatic detection and adjustment tool which is incorporated in the ventilator software., conditionsModule conditions: Mechanical Ventilation Complication, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: Two 2-hour periods: 1) "off mode" consisting of a control period with optimized ventilator parameters and 2) "on mode" with an active automated detection and adjustment for asynchronies. The starting first period is randomized., primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: Anonymized evaluation, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Intellisync+, outcomesModule primaryOutcomes measure: Duration of asyncronies, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hospital Clinico San Carlos, status: RECRUITING, city: Madrid, zip: 28040, country: Spain, contacts name: Miguel Sanchez-Garcia, MD, role: CONTACT, phone: +34658762739, email: miguelsanchez.hcsc@gmail.com, contacts name: Paloma Gonzalez-Arenas, MD, role: CONTACT, phone: +34 670 57 66 45, email: pgarenas@gmail.com, contacts name: David Janeiro Lumbreras, MD, role: SUB_INVESTIGATOR, contacts name: Fernando Suarez-Sipmann, MD, role: PRINCIPAL_INVESTIGATOR, contacts name: José Antonio Sánchez-Giralt, MD, role: SUB_INVESTIGATOR, geoPoint lat: 40.4165, lon: -3.70256, hasResults: False
protocolSection identificationModule nctId: NCT06295224, orgStudyIdInfo id: GOKAEK-2024/02.19, briefTitle: Retrospective Evaluation of Effect of Anterior Iliac Block, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2024-03-10, completionDateStruct date: 2024-03-15, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Kocaeli University, class: OTHER, descriptionModule briefSummary: In this study, the investigators aimed to evaluate the effect of ultrasound-guided anterior iliac block which was performed preoperatively. Anterior iliac bone harvesting is associated with severe postoperative pain. As several fascial plane blocks were defined to provide analgesia, their effects are debatable and requires high volumes of local anesthetic considering the regional anesthesia technique used for the main surgical procedure., conditionsModule conditions: Regional Anesthesia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: RETROSPECTIVE, enrollmentInfo count: 14, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Morphine consumption, secondaryOutcomes measure: NRS score, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Kocaeli Universty, status: RECRUITING, city: Kocaeli, country: Turkey, contacts name: Hadi Ufuk Yörükoğlu, role: CONTACT, email: ufukyorukoglu@gmail.com, geoPoint lat: 39.62497, lon: 27.51145, hasResults: False
protocolSection identificationModule nctId: NCT06295211, orgStudyIdInfo id: FEDII_HL_PR/R-Bv-Bs, briefTitle: Brentuximab Vedotin Combined With Bendamustine Supercharge, a Low-toxicity and Efficient Salvage Regimen for Primary Refractory or First-relapsed Classic Hodgkin Lymphoma: Long-term Results of a Retrospective Monocenter Study., acronym: HL_PR/R-B, statusModule overallStatus: COMPLETED, startDateStruct date: 2013-09-01, primaryCompletionDateStruct date: 2023-09-01, completionDateStruct date: 2024-02-22, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Federico II University, class: OTHER, descriptionModule briefSummary: This is a retrospective, monocenter and non-interventional study. Data were retrospectively collected from all patients who completed the BV-Bs scheme in the time period between 1 September 2013 and 1 September 2023., conditionsModule conditions: Hodgkin Lymphoma, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 32, type: ACTUAL, armsInterventionsModule interventions name: observational, outcomesModule primaryOutcomes measure: Overall survival, secondaryOutcomes measure: Progression overall survival, secondaryOutcomes measure: Response to treatment, secondaryOutcomes measure: Incidence of treatment emergent adverse events, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06295198, orgStudyIdInfo id: OPMM-Ankle Instability, briefTitle: The Effect of Different Talocrural Joint Mobilization Techniques in Lateral Ankle Sprain, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-07-30, primaryCompletionDateStruct date: 2024-03-01, completionDateStruct date: 2024-03-30, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Bahçeşehir University, class: OTHER, descriptionModule briefSummary: Decreased ankle dorsiflexion range of motion (DFROM) has been identified among the factors that increase the risk of lateral ankle sprain (LAS) in basketball players. Restoring the DFROM is important in restoring reduced functional abilities and reducing the risk of re-injury. There is evidence that talocrural joint mobilization improves DFROM, but studies investigating the effectiveness of different mobilization techniques are needed. Our study aims to investigate the effects of single-session Mulligan and Maitland talocrural joint mobilization methods on dorsiflexion joint range of motion, jumping performance, and kinesiophobia in elite basketball players., conditionsModule conditions: Ankle Sprains, conditions: Ankle Injuries, conditions: Kinesiophobia, conditions: Jumping From Height, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Participants with lateral ankle sprains will be randomized to the Mulligan and Maithland groups, and their evaluations and treatments will be completed., primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: After evaluations, the groups determined as a result of randomization via a website were placed in opaque envelopes. The participant is randomized to one of the Mulligan or Maitland groups by selecting an envelope., whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Single lep drop jump test, outcomesModule primaryOutcomes measure: Single-leg drop jump test, secondaryOutcomes measure: Weight-bearing lunge test, secondaryOutcomes measure: Tampa kinesiophobia scale, secondaryOutcomes measure: Fear Avoidance Belief Questionnaire, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 35 Years, stdAges: ADULT, contactsLocationsModule locations facility: Bahcesehir University, status: RECRUITING, city: Besiktas, state: Istanbul, zip: 34353, country: Turkey, contacts name: Pelin Pişirici, PT, PhD, role: CONTACT, phone: 05055016076, email: pelinpisirici@gmail.com, contacts name: Ozlem Feyzioglu, PT, PhD, role: CONTACT, phone: 05353529794, email: fztozlemfeyzioglu@gmail.com, hasResults: False
protocolSection identificationModule nctId: NCT06295185, orgStudyIdInfo id: AJOUIRB-IV-2024-097, briefTitle: Digital Therapeutic Workplace Technology as a Employee Management Tool and Employee's Mental Health Care, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-06-30, completionDateStruct date: 2024-07-01, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Ajou University School of Medicine, class: OTHER, descriptionModule briefSummary: The purpose of the study is to determine whether a digital healthcare app for employee's mental health can effectively improve the mental health of Hisbeans's employees and the managerial performance of Hisbeans, which is represented as a 'social enterprise'., conditionsModule conditions: Depression, conditions: Mental Health Issue, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 150, type: ESTIMATED, armsInterventionsModule interventions name: application MARO, interventions name: Sham application, outcomesModule primaryOutcomes measure: Change in network on the Standard Name Generator Approach scale, primaryOutcomes measure: Change in depression symptoms severity on the Patient Health Questionnaire-9, secondaryOutcomes measure: Change in social capital on the Social Capital Scale, secondaryOutcomes measure: Change in perceived workload on the Perceived Workload Scale, secondaryOutcomes measure: Change in job self-efficacy on the Job Self-Efficacy Scale, secondaryOutcomes measure: Change in sense of meaningfulness for job on the Sense of Meaningfulness for Job Scale, secondaryOutcomes measure: Change in work orientation toward his or her job on the Work Orientation Scale, secondaryOutcomes measure: Change in sense of psychological safety on the Perception of Psychological Safety Scale of Company Employees, secondaryOutcomes measure: Change in firm performance on the Company weekly sales records, secondaryOutcomes measure: Change in amsenteeism/leaves on the absenteeism/leave scales for employees with severe mental disabilities, secondaryOutcomes measure: Change in stress regulation skill on the Emotional/Cognitive/Behavioral State Questionnaire, secondaryOutcomes measure: Change in anxiety symptoms severity on the General Anxiety Disorder-7items scale, secondaryOutcomes measure: Change in perceived stress level on the Perceived Stress Scale, secondaryOutcomes measure: Change in social functioning on Social Adaptation Self Rating Scale, secondaryOutcomes measure: Change in positive psychological capital on Korean version of Positive Psychological Capital Scale, secondaryOutcomes measure: Change in Organizational Companionship on Organizational Culture Inventory, secondaryOutcomes measure: Change in individual's social network on Lubben Social Network Scale-18, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06295172, orgStudyIdInfo id: LF15_NLF_301, briefTitle: A Study Comparing Lafullen15 and Lafullen for Temporary Nasolabial Fold Improvement, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-29, primaryCompletionDateStruct date: 2025-09-30, completionDateStruct date: 2026-04-30, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Samyang Biopharmaceuticals Corporation, class: INDUSTRY, descriptionModule briefSummary: The objective of this clinical trial is to verify the safety and efficacy of Lafullen15 in the temporary improvement of nasolabial Folds, conditionsModule conditions: Nasolabial Folds, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: A Randomized, Evaluator-blind, Matched pairs, Prospective, Non inferiority, Confirmatory Study, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 73, type: ESTIMATED, armsInterventionsModule interventions name: Lafullen15, interventions name: Lafullen, outcomesModule primaryOutcomes measure: Changes in WSRS at 12 months after the last application of the clinical trial medical device compared to the baseline evaluated by an independent evaluator, eligibilityModule sex: ALL, minimumAge: 19 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06295159, orgStudyIdInfo id: MCC-22574, briefTitle: Biomarker Driven Patient Selection Neoadjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-28, primaryCompletionDateStruct date: 2027-03, completionDateStruct date: 2027-03, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-13, sponsorCollaboratorsModule leadSponsor name: H. Lee Moffitt Cancer Center and Research Institute, class: OTHER, descriptionModule briefSummary: The purpose of this study is to determine if neoadjuvant (treatment before surgery) immunotherapy treatment based on tumor biomarkers results in better participant outcomes. Immunotherapy is the treatment of disease by using a person's own immune system., conditionsModule conditions: Melanoma Stage III, conditions: Melanoma Stage IV, conditions: Advanced Melanoma, conditions: Melanoma, designModule studyType: INTERVENTIONAL, phases: EARLY_PHASE1, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Nivolumab, interventions name: Nivolumab + Relatlimab, interventions name: Ipilimumab, outcomesModule primaryOutcomes measure: Pathologic Major Response (pMR), secondaryOutcomes measure: Preoperative Radiologic Response Rate, secondaryOutcomes measure: Complete Pathologic Response Rate (pCR), secondaryOutcomes measure: Partial Pathologic Response Rate (pPR), secondaryOutcomes measure: Non-Response Pathologic Response Rate (pNR), secondaryOutcomes measure: Progression Free Survival (PFS), secondaryOutcomes measure: Overall Survival (OS), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Moffitt Cancer Center, status: RECRUITING, city: Tampa, state: Florida, zip: 33612, country: United States, contacts name: Justin Martin, role: CONTACT, phone: 813-745-7544, email: Justin.Martin@moffitt.org, contacts name: Ahmad Tarhini, MD, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 27.94752, lon: -82.45843, hasResults: False
protocolSection identificationModule nctId: NCT06295146, orgStudyIdInfo id: STUDY23050075, briefTitle: Virtual Peer Coaching in Manual Wheelchair Skills, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2026-12-30, completionDateStruct date: 2027-12-30, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: University of Pittsburgh, class: OTHER, descriptionModule briefSummary: The objective of this study is to determine the effectiveness of remote manual wheelchair skills training program. First, peer coaches will be enrolled and trained. Then, trainees will be enrolled into one of three interventions: intervention with remote feedback (Group 1), wait list control group (Group 2), and structured self-study (Group 3)., conditionsModule conditions: Wheelchair, conditions: Paraplegia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: SEQUENTIAL, interventionModelDescription: For trainees, we will use a randomized, single-blinded, two-period cross-over study design for Groups 1 and 2. Participants will complete baseline assessments and then be randomized to either Group 1 or Group 2. After we have completed enrollment for Groups 1 and 2 (N=40 per group) we will enroll participants into Group 3 ( N=40 per group)., primaryPurpose: BASIC_SCIENCE, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 132, type: ESTIMATED, armsInterventionsModule interventions name: Intervention A: 1-on-1 wheelchair skills training by a peer coach, interventions name: Intervention B: Training via educational videos, outcomesModule primaryOutcomes measure: Capacity, confidence, and performance of wheelchair skills will improve following training, secondaryOutcomes measure: Wheelchair Skills Test Questionnaire (WST-Q) improvement from baseline following training, secondaryOutcomes measure: Wheelchair Skills Test Questionnaire (WST-Q) improvement from baseline (6 months), secondaryOutcomes measure: Wheelchair Skills Test Questionnaire (WST-Q) improvement from baseline (12 months), secondaryOutcomes measure: Goal Attainment Scale (GAS) improvement from baseline (post training), secondaryOutcomes measure: Craig Handicap Assessment and Reporting Technique Short Form (CHART-SF) Mobility improvement (6 months), secondaryOutcomes measure: Craig Handicap Assessment and Reporting Technique Short Form (CHART-SF) Mobility improvement (1 year), secondaryOutcomes measure: Wheelchair Outcome Measure (WhOM) Satisfaction with Participation in Meaningful Activities after baseline (6 months), secondaryOutcomes measure: Wheelchair Outcome Measure (WhOM) Satisfaction with Participation in Meaningful Activities after baseline (1 year), secondaryOutcomes measure: Life Space Assessment (LSA) improvement from baseline (6 months), secondaryOutcomes measure: Life Space Assessment (LSA) improvement from baseline (1 year), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False