hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06303908, orgStudyIdInfo id: Commu-PKS, briefTitle: How Traditional Chinese Medicine Exercise Improves Parkinson Disease, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-11, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: Muhammad, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to explore the impact of Simple Gymnastics Training on Limb motor function and mental health in Parkinson's Patients in the Community (≥60 year old) with swallowing disorders. It primarily aims to address two key aspects: 1) the prevalence of Parkinson's Diseases among community-dwelling elderly individuals, and 2) the effects of Simple Gymnastics Training on Limb motor function and mental health in community-dwelling Parkinson's Patients. All patients are required to undergo a continuous three-week (21 days) Simple Gymnastics Training, with weekends off and training conducted only on weekdays. The training will be conducted two sessions per day, lasting 30 minutes each., conditionsModule conditions: Parkinson Disease, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 300, type: ESTIMATED, armsInterventionsModule interventions name: Simple Gymnastics Training, outcomesModule primaryOutcomes measure: Unified Parkinson's Disease Rating Scale, secondaryOutcomes measure: The Berg Balance Scale, secondaryOutcomes measure: Patient Health Questionnaire-9, secondaryOutcomes measure: Generalized Anxiety Disorder-7, eligibilityModule sex: ALL, minimumAge: 60 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06303895, orgStudyIdInfo id: Acu-PKS-new, briefTitle: How Acupuncture Therapy Improves Dysphagia in Parkinson's Patients, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2024-06, completionDateStruct date: 2024-06, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-13, sponsorCollaboratorsModule leadSponsor name: Muhammad, class: OTHER, descriptionModule briefSummary: This study is focusing on dysphagic participants with Parkinson's disease. The aim of our study is to evaluate the effectiveness of acupuncture therapy as an additional intervention for these participants. Participants were randomly assigned to either the experimental group or the control group, with 56 individuals in each group. Both groups are receiving standard treatment and swallowing rehabilitation training, while the experimental group is also receiving acupuncture therapy. Our study aims to provide valuable insights into the potential benefits of acupuncture in improving swallowing difficulties in Parkinson's disease participants., conditionsModule conditions: Dysphagia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Routine rehabilitation training, interventions name: Swallowing rehabilitation training, interventions name: Acupuncture therapy, outcomesModule primaryOutcomes measure: Penetration-Aspiration Scale-liquid, primaryOutcomes measure: Penetration-Aspiration Scale-paste, secondaryOutcomes measure: Swallowing time, secondaryOutcomes measure: body mass index, secondaryOutcomes measure: Serum Albumin, secondaryOutcomes measure: Prealbumin, secondaryOutcomes measure: Hemoglobin, secondaryOutcomes measure: Swallowing Quality of Life, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06303882, orgStudyIdInfo id: AI-Dysphagia, briefTitle: Effect of Computer-based Cognitive Function Training on Cognitive Dysphagia After Stroke, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2024-06, completionDateStruct date: 2024-06, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: Muhammad, class: OTHER, descriptionModule briefSummary: This is a multicenter randomized controlled study. The study recruited stroke patients with mild cognitive impairment and dysphagia who were undergoing inpatient rehabilitation treatment in three hospitals in mainland China as the participants (study subjects). The study duration for each participant was 15 days. The subjects were randomly divided into an experimental group and a control group. During the treatment, all patients received routine rehabilitation treatment. In addition, patients in the control group received conventional cognitive training, while patients in the experimental group received computer-assisted cognitive training., conditionsModule conditions: Dysphagia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: routine rehabilitation treatment, interventions name: Computer-assisted Cognitive Function Training, interventions name: conventional cognitive training, outcomesModule primaryOutcomes measure: Montreal Cognitive Assessment, secondaryOutcomes measure: The coordination of swallowing, secondaryOutcomes measure: Penetration-Aspiration Scale, secondaryOutcomes measure: Swallowing duration, secondaryOutcomes measure: Swallowing reflex, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06303869, orgStudyIdInfo id: STUDY22070043, briefTitle: Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2029-05, completionDateStruct date: 2029-10, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Jorge Gonzalez-Martinez, class: OTHER, descriptionModule briefSummary: The goal of this study is to verify whether the use of deep brain stimulation can improve motor function of the hand and arm and speech abilities for people following a stroke. Participants will undergo a surgical procedure to implant deep brain stimulation electrode leads. The electrodes will be connected to external stimulators and a series of experiments will be performed to identify the types of movements that the hand and arm can make and how speech abilities are affected by the stimulation. The implant will be removed after less than 30 days. Results of this study will provide the foundation for future studies evaluating the efficacy of a minimally-invasive neuro-technology that can be used in clinical neuro-rehabilitation programs to restore speech and upper limb motor functions in people with subcortical strokes, thereby increasing independence and quality of life., conditionsModule conditions: Stroke, conditions: Brain Disease, conditions: Central Nervous System Diseases, conditions: Nervous System Diseases, conditions: Cardiovascular Diseases, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: Prospective, non-randomized, open-label, descriptive, experimental., primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 10, type: ESTIMATED, armsInterventionsModule interventions name: Deep Brain Stimulation (DBS) of the Motor Thalamus, outcomesModule primaryOutcomes measure: Adverse Events, primaryOutcomes measure: Discomfort and Pain, secondaryOutcomes measure: Dysphagia, secondaryOutcomes measure: Hand dexterity, secondaryOutcomes measure: Muscle weakness, secondaryOutcomes measure: Dexterity of Articulation AMRs, secondaryOutcomes measure: Dexterity of Articulation SMRs, secondaryOutcomes measure: Intelligibility of Speech, secondaryOutcomes measure: Spasticity, secondaryOutcomes measure: Range of Motion (ROM), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Pittsburgh, city: Pittsburgh, state: Pennsylvania, zip: 15213, country: United States, contacts name: Cierra Clark, MS, role: CONTACT, phone: 240-441-4216, email: cic27@pitt.edu, geoPoint lat: 40.44062, lon: -79.99589, hasResults: False
protocolSection identificationModule nctId: NCT06303856, orgStudyIdInfo id: ABE-OLDer, briefTitle: How Active Breathing Training Improves Dysphagia in Elderly People, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2024-05, completionDateStruct date: 2024-05, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-13, sponsorCollaboratorsModule leadSponsor name: Muhammad, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to explore the impact of Active Breathing Exercises on swallowing function and quality of life in community-dwelling elderly individuals (≥60 year old) with swallowing disorders. It primarily aims to address two key aspects: 1) the prevalence of dysphagia among community-dwelling elderly individuals, and 2) the effects of Active Breathing Exercises on swallowing function and quality of life in community-dwelling elderly individuals with swallowing disorders. All participants enrolled are required to undergo a continuous three-week (21 days) Active Breathing Exercises, with weekends off and training conducted only on weekdays. The training will be conducted two sessions per day, lasting 15-30 minutes each., conditionsModule conditions: Dysphagia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 300, type: ESTIMATED, armsInterventionsModule interventions name: Active Breathing Exercises, outcomesModule primaryOutcomes measure: Eating Assessment Tool-10, secondaryOutcomes measure: Time consumed in eating, secondaryOutcomes measure: Swallowing-Related Quality of Life Questionnaire, eligibilityModule sex: ALL, minimumAge: 60 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06303843, orgStudyIdInfo id: 13.04.2023, briefTitle: The Effect of Electric Ride-On Cars Use During Transport to the Operating Theatre, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-05-02, primaryCompletionDateStruct date: 2024-02-15, completionDateStruct date: 2024-02-15, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Uşak University, class: OTHER, descriptionModule briefSummary: The aim of our study was to evaluate the effect of the use of a electric ride-on car during transport to the operating theatre on preoperative anxiety in children undergoing elective ambulatory surgery. As a distraction method, children in the experimental group will be introduced to the operating theatre with a electric ride-on car. Yale Modified Preoperative Anxiety Scale Child Form will be used to evaluate anxiety. The sample size was determined as 118 as a result of power analysis. 59 children will be included in the experimental group and 59 children in the control group.Translated with DeepL.com (free version), conditionsModule conditions: Anxiety, conditions: Preoperative Anxiety, conditions: Pediatric Surgery, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 118, type: ACTUAL, armsInterventionsModule interventions name: Transfer with an electric ride-on car, outcomesModule primaryOutcomes measure: Perioperative anxiety, eligibilityModule sex: ALL, minimumAge: 2 Years, maximumAge: 10 Years, stdAges: CHILD, contactsLocationsModule locations facility: Usak University Training and Research Hospital, city: Usak, zip: 64100, country: Turkey, geoPoint lat: 38.67351, lon: 29.4058, hasResults: False
protocolSection identificationModule nctId: NCT06303830, orgStudyIdInfo id: BACA2019, briefTitle: Bariatric Surgery and Cardiovascular Responses to Sodium Nitrate, statusModule overallStatus: COMPLETED, startDateStruct date: 2019-04-16, primaryCompletionDateStruct date: 2020-12-17, completionDateStruct date: 2021-10-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: University of Sao Paulo, class: OTHER, descriptionModule briefSummary: Inorganic nitrite and nitrate can be reduced to NO and NO-related species such as S-nitrosothiols via the nitrate-nitrite-NO pathway. This is due to the reduction of nitrate to nitrite by the action of bacteria in the mouth and the reduction of nitrite to NO depending on the acidic pH on the stomach or by enzymes with nitrite-reductase activity. The acidic environment of the stomach is very important to the formation of NO and S-nitrosothiols and several studies suggest that changes in gastric pH can affect this conversion. In this context, bariatric surgery, by altering the anatomy of the stomach and increasing gastric pH, can affect the nitrate-nitrite-NO pathway and change the antihypertensive and antioxidant effect of sodium nitrate., conditionsModule conditions: Hypertension, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ACTUAL, armsInterventionsModule interventions name: Sodium nitrate, outcomesModule primaryOutcomes measure: Assess changes in s-nitrosothiols, secondaryOutcomes measure: Assess changes in blood pressure, secondaryOutcomes measure: Assess changes in endotelial function, secondaryOutcomes measure: Assess changes in Vascular stiffness, secondaryOutcomes measure: Assess changes in nitrate concentration, secondaryOutcomes measure: Assess changes in nitrite concentration, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Usp - Hospital Das Clínicas Da Faculdade de Medicina de Ribeirão, city: Ribeirão Preto, state: São Paulo, zip: 14.048-900, country: Brazil, geoPoint lat: -21.1775, lon: -47.81028, hasResults: False
protocolSection identificationModule nctId: NCT06303804, orgStudyIdInfo id: HSC-SPH-23-0837, briefTitle: Prevention of Opioid Misuse and Overdose Deaths Among Hispanic/Latinx Adolescents: A Family-based Perspective, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2024-08-31, completionDateStruct date: 2024-08-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: The University of Texas Health Science Center, Houston, class: OTHER, descriptionModule briefSummary: The purpose of this study is to develop culturally-competent family-focused educational modules targeting opioid knowledge and attitudes (including targeting safe storage and prevention of accidental opioid overdose in adolescent populations) and examine changes acceptability, knowledge, and attitudes scores, conditionsModule conditions: Opioid Misuse, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Educational videos, outcomesModule primaryOutcomes measure: Acceptability of the educational materials presented via the educational videos, including cultural congruence as assessed by a questionnaire, primaryOutcomes measure: Changes in opioid related knowledge as assessed by a questionnaire, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The University of Texas Health Science Center at Houston, city: Houston, state: Texas, zip: 77030, country: United States, contacts name: Alejandra Fernandez, PhD, role: CONTACT, phone: 972-546-2920, email: Alejandra.Fernandez@uth.tmc.edu, geoPoint lat: 29.76328, lon: -95.36327, hasResults: False
protocolSection identificationModule nctId: NCT06303752, orgStudyIdInfo id: 260-2021-NQ, secondaryIdInfos id: 2022-502659-73, type: EUDRACT_NUMBER, briefTitle: Tissue Therapy of Transsphincteric Anal Fistula, acronym: REP-PAF, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2027-04-30, completionDateStruct date: 2027-04-30, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-04-12, sponsorCollaboratorsModule leadSponsor name: University of Southern Denmark, class: OTHER, descriptionModule briefSummary: This clinical study aims to evaluate the outcome of the treatment of complex perianal fistulas (PAF) by the combination of minimal surgical debridement with regenerative cellular therapeutics., conditionsModule conditions: Anal Fistula, designModule studyType: INTERVENTIONAL, phases: PHASE1, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 75, type: ESTIMATED, armsInterventionsModule interventions name: ADRC injection, interventions name: ADRC001 injection, outcomesModule primaryOutcomes measure: Healing rate (percentage), secondaryOutcomes measure: QoL, secondaryOutcomes measure: Fecal Incontinence, secondaryOutcomes measure: Risk factors for recurrence of fistula., secondaryOutcomes measure: Radiological healing., secondaryOutcomes measure: Treatment efficacy., secondaryOutcomes measure: Cellular composition, secondaryOutcomes measure: Transplantation-related alloantibodies, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Odense University Hospital, city: Odense, zip: 5000, country: Denmark, contacts name: Karam M Sørensen, Ph.D, role: CONTACT, phone: +4565415190, email: ouh.a.forskningsenheden@rsyd.dk, contacts name: Tina D Hansen, role: CONTACT, phone: +4565415190, email: ouh.a.forskningsenheden@rsyd.dk, geoPoint lat: 55.39594, lon: 10.38831, hasResults: False
protocolSection identificationModule nctId: NCT06303726, orgStudyIdInfo id: IRP-2021/02-19, briefTitle: Comparison of Single-bundle Versus Double-bundle Anterior Cruciate Ligament Reconstruction, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2022-04-25, primaryCompletionDateStruct date: 2024-04-01, completionDateStruct date: 2024-06-25, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: University Medical Centre Maribor, class: OTHER, descriptionModule briefSummary: The goal of this retrospective randomized study is to compare two surgical techniques (single vs. double bundle) of ACL (anterior cruciate ligament) reconstructions in participants with rupture of anterior cruciate ligament without major other injuries of the injured knee (exclusion criteria defined).The main question it aims to answer are:* which surgery gives better outcome in patients (short- and long-term results)?* are there any sings of osteoarthritis in an injured knee compared to a healthy knee?Participants will be invited to our clinic after 15 years to do clinical and functional exams with x-Ray and magnetic resonance imaging (MRI) of both knees. Subjective exams with different scores (Tegner score, Lysholm score..) were also done. The same exam protocol for participant was used again after two years and fifteen years since surgery., conditionsModule conditions: Anterior Cruciate Ligament Reconstruction, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 30, type: ACTUAL, armsInterventionsModule interventions name: ACL reconstruction single bundle, interventions name: ACL reconstruction double bundle, outcomesModule primaryOutcomes measure: IKDC SUBJECTIVE SCORE, primaryOutcomes measure: TEGNER SCORE, primaryOutcomes measure: LYSHOLM SCORE, primaryOutcomes measure: OBJECTIVE PARAMETER: STREENGHT OF FLEXORS AND EXTENSORS, primaryOutcomes measure: OBJECTIVE PARAMETER: AP TRANSLATION (anterior-posterior), eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University Clinical Center Maribor, city: Maribor, zip: 2000, country: Slovenia, geoPoint lat: 46.55472, lon: 15.64667, hasResults: False