hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06317181, orgStudyIdInfo id: DifLivSPECTRUS, briefTitle: Assessment of Liver Diseases Using a Deep-Learning Approach Based on Ultrasound RF-Data, acronym: LivSPECTRUS, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-06, completionDateStruct date: 2025-12, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Technische Universität Dresden, class: OTHER, collaborators name: University Hospital Dresden, collaborators name: University of Leipzig, descriptionModule briefSummary: The goal of this clinical trial is to test the performance of neuronal networks trained on ultrasonic raw Data (=radiofrequency data) for the assessment of liver diseases in patients undergoing a clinical ultrasound examination. The general feasibility is currently evaluated in a retrospective cohort.The main questions the study aims to answer are:* Can a neuronal network trained on RF Data perform equally good as elastography in the assessment of diffuse liver diseases?* Can a neuronal network trained on RF Data perform better than a neuronal network trained on b-mode images in the assessment of diffuse liver diseases?* Can a neuronal network trained on RF Data distinguish focal pathologies in the liver from healthy tissue?To answer these questions participants with a clinically indicated fibroscan will undergo:* a clinical elastography in Case ob suspected diffuse liver disease* a reliable ground truth (if normal ultrasound is not sufficient e.g. contrast enhanced ultrasound, biopsy, MRI or CT) in case of focal liver diseases, depending on the standard routine of the participating center* a clinical ultrasound examination during which b-mode images and the corresponding RF-Data sets are captured, conditionsModule conditions: Artificial Intelligence, conditions: Ultrasonography, conditions: Elasticity Imaging Techniques, conditions: Liver Diseases, conditions: Metastasis to Liver, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Data is collected in a defined group of patients (all patients listed for elastography or for ultrasonic investigation due to a focal lesion in participating departments). Afterwards performances of algorithms are compared based on this group., primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: Collection of elastography data, interventions name: Collection of ultrasonic raw data, outcomesModule primaryOutcomes measure: Performance analysis of the trained model, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, documentSection largeDocumentModule largeDocs typeAbbrev: Prot, hasProtocol: True, hasSap: False, hasIcf: False, label: Study Protocol, date: 2024-03-01, uploadDate: 2024-03-15T03:02, filename: Prot_000.pdf, size: 271228, hasResults: False
protocolSection identificationModule nctId: NCT06317168, orgStudyIdInfo id: SIMPLE-AOBP, briefTitle: SIMPLifying Elements of Standardized Automated Office Blood Pressure Measurements (Pilot Study), acronym: SIMPLE-AOBP, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2024-08-31, completionDateStruct date: 2024-08-31, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal, class: OTHER, descriptionModule briefSummary: This study aims to assess whether removing single elements of the standardized office BP measurement procedure will affect the accuracy towards the mean awake ambulatory BP. Four arms are planned in a randomized order: 1) full standardized procedure, 2) standardized procedure but with cuff placed on a sleeve, 3) standardized procedure but arm resting vertically, 4) standardized procedure but with non-validated device.This is a pilot study to inform on the sample size required to perform adequately powered large scale studies., conditionsModule conditions: Blood Pressure, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: DIAGNOSTIC, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Mean awake ambulatory BP measurements, outcomesModule primaryOutcomes measure: Difference with mean awake ambulatory systolic BP, secondaryOutcomes measure: Difference with mean awake ambulatory diastolic BP, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06317155, orgStudyIdInfo id: BournemouthU-AS, briefTitle: Occupational Therapy for Children and Young People Who Self-harm: A Qualitative Study, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-12, primaryCompletionDateStruct date: 2025-09, completionDateStruct date: 2025-12, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Bournemouth University, class: OTHER, collaborators name: Dorset HealthCare University NHS Foundation Trust, descriptionModule briefSummary: The goal of this qualitative observational study is to explore the experiences of children and their carers, receiving occupational therapy for self-harm and the experiences of health professionals delivering these interventions. The child cohort within the study will have a history of self-harm and have been under the care of Children and Adolescent Mental Health Services.The main questions it aims to answer are:* What are the experiences of children and their carers who have received occupational therapy interventions as either a standalone, or adjunct, treatment for self-harm, whilst under the care of Tier 4 CAMHS service.* What are the experiences of healthcare professionals delivering occupational therapy interventions working within a T4 CAMHS service.* To understand the participants views on whether occupational therapy interventions are a viable and effective approach to address self-harm amongst young people.Participants will be asked to complete a questionnaire and take part in a single semi-structured interview. 25% of participants may be asked to take part in a further in depth semi-structured interview., conditionsModule conditions: Self Harm, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Occupational therapy, outcomesModule primaryOutcomes measure: What was the participants experience of receiving or delivering an occupational therapy informed intervention?, primaryOutcomes measure: What was the participants experience of receiving or delivering an occupational therapy informed intervention?, primaryOutcomes measure: Did the participants feel the occupational therapy informed interventions were effective in supporting young people who self-harm or effective in reducing self-harm?, primaryOutcomes measure: Did the participants feel the occupational therapy informed interventions were effective in supporting young people who self-harm or effective in reducing self-harm?, eligibilityModule sex: ALL, minimumAge: 13 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06317129, orgStudyIdInfo id: CP000005, briefTitle: Clinical Feasibility Study of the BariTon™ System in Obese Patients, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-18, primaryCompletionDateStruct date: 2024-10-31, completionDateStruct date: 2026-01-31, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: BariaTek Medical, class: INDUSTRY, descriptionModule briefSummary: Safety evaluation of BariaTek Medical gastric restriction and biliodigestive diversion device., conditionsModule conditions: Obesity, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 10, type: ESTIMATED, armsInterventionsModule interventions name: Endoscopic gastric restriction and biliodigestive diversion, outcomesModule primaryOutcomes measure: Safety of the BariTon™, primaryOutcomes measure: Safety of the BariTon™, secondaryOutcomes measure: Safety of the BariTon™, secondaryOutcomes measure: Safety of the BariTon™, secondaryOutcomes measure: Efficacy of the BariTon™, secondaryOutcomes measure: Efficacy of the BariTon™, secondaryOutcomes measure: Efficacy of the BariTon™, secondaryOutcomes measure: Efficacy of the BariTon™, secondaryOutcomes measure: Efficacy of the BariTon™, secondaryOutcomes measure: Efficacy of the BariTon™, eligibilityModule sex: ALL, minimumAge: 25 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Republican Specialized Scientific and Practical Medical Center of Surgery named after V. Vakhidov, status: RECRUITING, city: Tashkent, country: Uzbekistan, contacts name: Abdurashid Abdukarimov, Dr, role: CONTACT, geoPoint lat: 41.26465, lon: 69.21627, hasResults: False
protocolSection identificationModule nctId: NCT06317116, orgStudyIdInfo id: 2023/09-14, briefTitle: Examining the Relationship Between Core Muscles and Bladder Issues in Children, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2023-09-29, primaryCompletionDateStruct date: 2024-09-29, completionDateStruct date: 2025-03-01, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Izmir Bakircay University, class: OTHER, collaborators name: Dokuz Eylul University, collaborators name: Ege University Medical School, collaborators name: The Scientific and Technological Research Council of Turkey, descriptionModule briefSummary: The goal of this observational study is to learn about functional bladder problems in children. The main questions it aims to answer are:* Does bladder symptoms in children have an effect on core muscles?* How do core muscles change based on an increase or decrease in these symptoms?, conditionsModule conditions: Lower Urinary Tract Symptoms, conditions: Skeletal Muscle, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 60, type: ESTIMATED, outcomesModule primaryOutcomes measure: Dysfunctional Voiding and Incontinence Scoring System (DVAISS), primaryOutcomes measure: Bladder and Bowel Dysfunction Questionnaire (BBDQ), primaryOutcomes measure: Childhood Bladder and Bowel Dysfunction Questionnaire (CBBDQ), primaryOutcomes measure: Bladder Diary, primaryOutcomes measure: Bowel Diary, secondaryOutcomes measure: Superficial Electromyography (EMG), secondaryOutcomes measure: Ultrasonography (USG), eligibilityModule sex: ALL, minimumAge: 6 Years, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Ege University Hospital Pediatric Urology Outpatient Clinic, city: İzmir, country: Turkey, geoPoint lat: 38.41273, lon: 27.13838, hasResults: False
protocolSection identificationModule nctId: NCT06317103, orgStudyIdInfo id: WAY-CTP-WME01-MSM, briefTitle: A Clinical Trial to Evaluate the Sensitivity and Specificity of "WAYMED Endo" Compared to the Endoscopists in Classifying Early Gastric Cancer (EGC) Based on the Depth of Invasion in Endoscopic Images, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-08-22, primaryCompletionDateStruct date: 2023-08-22, completionDateStruct date: 2023-08-22, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: WAYCEN Inc, class: INDUSTRY, descriptionModule briefSummary: The purpose of this clinical trial is to prove that the prediction capability of 'WAYMED endo' is superior to that of the endoscopists in classifying EGC based on the depth of invasion categories in gastro-endoscopic images.The computer-aided detection·diagnosis software is an Artificial Intelligence (AI) software used to assist medical specialists in diagnostic decisions by automatically classifying EGC based on the depth of invasion categories in gastro-endoscopic images and displaying the results and possibilities on the User Interface (UI)., conditionsModule conditions: Early Gastric Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: RETROSPECTIVE, enrollmentInfo count: 653, type: ACTUAL, armsInterventionsModule interventions name: WADYMED endo, interventions name: Control group (the endoscopists), outcomesModule primaryOutcomes measure: Clinical Sensitivity in classifying early gastric cancer (EGC) based on the depth of invasion (%), primaryOutcomes measure: Clinical Specificity in classifying early gastric cancer (EGC) based on the depth of invasion (%), secondaryOutcomes measure: Accuracy in classifying the depth of invasion categories ("Mucosa" or "Submucosa") for early gastric cancer (%), eligibilityModule sex: ALL, minimumAge: 19 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Yonsei University Gangnam Severance Hospital, city: Seoul, country: Korea, Republic of, geoPoint lat: 37.566, lon: 126.9784, hasResults: False
protocolSection identificationModule nctId: NCT06317090, orgStudyIdInfo id: S59813-2, briefTitle: Vertical GBR LPRF Block vs. Autogenous Bone With DBBM, statusModule overallStatus: COMPLETED, startDateStruct date: 2018-07-02, primaryCompletionDateStruct date: 2023-03-01, completionDateStruct date: 2023-03-01, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Universitaire Ziekenhuizen KU Leuven, class: OTHER, descriptionModule briefSummary: split-mouth RCT, 25 months follow up. GBR protocol with LPRF as grafting material in the test group and autogenous bone with DBBM as grafting material in the control group., conditionsModule conditions: Alveolar Bone Resorption, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: split-mouth 2 arm RCT, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: neither the patient, nor the outcome assessor was aware at which side which grafting material was used, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 6, type: ACTUAL, armsInterventionsModule interventions name: guided bone regeneration, outcomesModule primaryOutcomes measure: bone volume as measured on CBCT scans, secondaryOutcomes measure: Buccal bone thickness around the implants, secondaryOutcomes measure: Buccal bone thickness around the implants, secondaryOutcomes measure: Cumulative survival rate of the implants, secondaryOutcomes measure: rates and types of complications, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: UZ Leuven, city: Leuven, state: Vlaams-Brabant, zip: 3000, country: Belgium, geoPoint lat: 50.87959, lon: 4.70093, hasResults: False
protocolSection identificationModule nctId: NCT06317064, orgStudyIdInfo id: LMRC-Aprepitant-Pain-01, briefTitle: Diagnostic and Therapeutic Potential of Substance P/ NK1R Receptor in Primary Dysmenorrhea, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-01-15, primaryCompletionDateStruct date: 2023-10-31, completionDateStruct date: 2024-01-31, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Lahore Medical Research Center, LLP, class: INDUSTRY, descriptionModule briefSummary: Dysmenorrhea is characterized as excruciating menstrual cramps of uterine origin and is one of the most prevalent gynecological illnesses. Substance P (SP) and NK1R mediate the symptoms of various pain disorders with chronic and/or neuropathic pain. Objective: To evaluate diagnostic and therapeutic potential of Substance P/ NK1R receptor in primary dysmenorrhea. Study Design: This was a randomized controlled trial which took place at Lahore Medical Research Center from April 2023 to August 2023. Non-probability convenient sampling techniques was used for sampling. A total of 40 female participants was included in the study who met specific criteria for inclusion. The study comprised of three phases, Phase 1 (Before medication), Phase 2 (NSAIDs) and Phase 3(Dexamethasone + Aprepitant). 10 females with no dysmenorrhea participated as controls. The study duration spanned three menstrual cycles. 20 dysmenhorric and 6 controls were analyzed for NK1R levels. Several assessment tools were also used in the study,, conditionsModule conditions: Primary Dysmenorrhea, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: SEQUENTIAL, interventionModelDescription: Group 1: Controls 10 females with no dysmenorrhea participated as controls. Group 2: NSAIDS All 30 participants in this group used NSAIDs (Non-steroidal Anti-Inflammatory Drugs), during their dysmenorrhea period. Same patients from phase 2 (n=30) in next cycle received NK1R antagonist "Dexamethasone (6mg) + Aprepitant (80mg)" for 2 days., primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ACTUAL, armsInterventionsModule interventions name: Ibuprofen and Aprepitant, outcomesModule primaryOutcomes measure: Visual Analogue Scale Score (Pain scale), primaryOutcomes measure: Mini Nutritional Assessment (MNA) Score, primaryOutcomes measure: DASS-21 (Depression Anxiety Stress Scale), primaryOutcomes measure: Pictorial Blood Loss Assessment Chart (PBAC), eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule locations facility: Prof. Dr. Riffat Mehboob, city: Lahore, state: Punjab, zip: 54000, country: Pakistan, geoPoint lat: 31.558, lon: 74.35071, hasResults: False
protocolSection identificationModule nctId: NCT06317038, orgStudyIdInfo id: 89814415, briefTitle: To Evaluate the Performance of Total 30 (Lehifilcon A) Contact Lenses in Patients Using Digital Devices for Greater Than 8 Hours Per Day 5 Days Per Week Based on Subjective Reported Data., statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-31, primaryCompletionDateStruct date: 2024-11, completionDateStruct date: 2025-01, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Tauber Eye Center, class: OTHER, collaborators name: Alcon Research, descriptionModule briefSummary: To evaluate the performance of Total 30® (lehfilcon A) contact lenses in patients using digital devices for greater than 8 hours per day 5 days per week based on subjective reported data., conditionsModule conditions: Eye Strain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: Open label Observation, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Total 30 Contact Lens, outcomesModule primaryOutcomes measure: Likert question about comfort satisfaction while wearing Total 30 contact lenses on a typical day (> 13 hours of daily wear) after 1 month of wear and heavy digital device usage (>8 hours daily wear)., secondaryOutcomes measure: Likert responses to insertion comfort and overall vision, and heavy digital device use on a typical day after 1 month of wear., secondaryOutcomes measure: Results of subjective ratings of patients using Total 30 lenses and heavy digital device usage with VAS diary questionnaire., secondaryOutcomes measure: Report on total daily wear time and digital device usage., eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06317025, orgStudyIdInfo id: SHOUFA2022-2Z-2039, briefTitle: Design and Development of Multi-modal Intelligent Anesthesia Monitoring System, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2025-12, completionDateStruct date: 2025-12, studyFirstPostDateStruct date: 2024-03-19, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Beijing Chao Yang Hospital, class: OTHER, descriptionModule briefSummary: This project integrates the characteristics of electroencephalo-graph（EEG）, cerebral oxygen, blood pressure, heart rate, etc., based on nonlinear theory and neural oscillation, large sample data and machine learning theory, to develop a multi-modal monitoring system suitable for domestic patients, taking into account changes in sedation, analgesia, cerebral hemodynamics and other factors, regardless of patient age and type of general anesthesia drugs., conditionsModule conditions: Anesthesia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 330, type: ESTIMATED, armsInterventionsModule interventions name: Multi-modal Intelligent Anesthesia Monitoring System, outcomesModule primaryOutcomes measure: the depth of anesthesia (too deep or too shallow), secondaryOutcomes measure: EEG characteristics of loss of consciousness induced by different general anesthesia drugs, secondaryOutcomes measure: Characteristics of perioperative neurovascular coupling, eligibilityModule sex: ALL, maximumAge: 85 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False