hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06335706, orgStudyIdInfo id: 0596/66, briefTitle: The Influence of Fit of Underpants Worn on Semen Quality, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2024-05, completionDateStruct date: 2024-05, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Chulalongkorn University, class: OTHER, descriptionModule briefSummary: The goal of this observational study is to investigate the impact of underpants fit among Thai males attending the Infertility Clinic, whether alone or with their spouses. The main questions it aims to answer are:* Assessing the effect of underpants fit on basic semen parameters and sperm DNA integrity.* Determining the prevalence of preferred type of underpants worn by Thai males.The participants will need to provide informed consent, complete a questionnaire consisting of 28 questions, and provide a semen sample., conditionsModule conditions: Infertility, Male, conditions: Semen Analysis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: Fit of underpants worn, outcomesModule primaryOutcomes measure: Semen Volume, primaryOutcomes measure: Total sperm count, primaryOutcomes measure: Sperm concentration, primaryOutcomes measure: Sperm motility, primaryOutcomes measure: Sperm morphology, secondaryOutcomes measure: Sperm DNA integrity, otherOutcomes measure: Preferred type of underpants, eligibilityModule sex: MALE, minimumAge: 20 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06335693, orgStudyIdInfo id: CHHHospital, briefTitle: Adjuvant Hypofractionated Radiotherapy for Prostate Cancer, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-28, primaryCompletionDateStruct date: 2026-02-28, completionDateStruct date: 2027-02-28, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Changhai Hospital, class: OTHER, descriptionModule briefSummary: Hypofractionated radiation therapy is a new type of radiotherapy which has been shown to play a larger role in the treatment of prostate cancer. The aims of the trial were to evaluate the safety and feasibility of adjuvant hypofractionated radiotherapy following radical prostatectomy for prostate cancer., conditionsModule conditions: Prostate Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 9, type: ESTIMATED, armsInterventionsModule interventions name: Radiotherapy, outcomesModule primaryOutcomes measure: Incidence of radiotherapy-related gastrointestinal and genitourinary adverse events, secondaryOutcomes measure: progression-free survival (PFS), secondaryOutcomes measure: medical expenses, secondaryOutcomes measure: quality of life(QoL), secondaryOutcomes measure: overall survival (OS), secondaryOutcomes measure: prostate cancer-specific survival (CSS), eligibilityModule sex: MALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The First Affiliated Hospital of Naval Medical University, status: RECRUITING, city: Shanghai, state: Shanghai, zip: 200433, country: China, contacts name: Huojun Zhang, PhD, role: CONTACT, phone: 021-31162222, email: huojunzh@163.com, geoPoint lat: 31.22222, lon: 121.45806, hasResults: False
protocolSection identificationModule nctId: NCT06335680, orgStudyIdInfo id: 21-001493, briefTitle: [Trial of device that is not approved or cleared by the U.S. FDA], statusModule overallStatus: WITHHELD, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: [Redacted], hasResults: False
protocolSection identificationModule nctId: NCT06335667, orgStudyIdInfo id: 4565, secondaryIdInfos id: UCI 23-72, type: OTHER, domain: UCI CFCCC, briefTitle: mpMRI Compared to Diagnostic TURBT in Patients With Suspected Muscle-Invasive Bladder Cancer Objectives, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-04, completionDateStruct date: 2030-04, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: University of California, Irvine, class: OTHER, descriptionModule briefSummary: This is a pilot, single arm, prospective study that aims to validate the accuracy of the VI-RADS score obtained via multi-parametric magnetic resonance imaging (mpMRI) compared to pathologic cancer stage obtained via diagnostic transurethral bladder tumor resection (TURBT) as well as compare the clinical and quality of life outcomes between these diagnostic modalities in patients with suspected muscle-invasive bladder cancer (MIBC)., conditionsModule conditions: Urothelial Bladder Cancer, conditions: Muscle-Invasive Bladder Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: mpMRI + Diagnostic TURBT, outcomesModule primaryOutcomes measure: Incidence of concordance between VI-RADS score of 4 or 5 (i.e. muscular propria is likely or very likely) on mpMRI and pathologic muscularis propria invasion (i.e. pT2 tumor stage) on diagnostic TURBT., secondaryOutcomes measure: Progression free survival (PFS) with mpMRI compared to diagnostic TURBT, secondaryOutcomes measure: Time from intervention that determines invasiveness of bladder tumors (i.e. diagnostic TURBT versus mpMRI) to initiation of cancer-directed therapy, secondaryOutcomes measure: Time from initial cystoscopy to intervention that determines invasiveness of bladder tumors (i.e diagnostic TURBT versus mpMRI)., secondaryOutcomes measure: Incidence of adverse events with mpMRI versus diagnostic TURBT., secondaryOutcomes measure: Patient Quality of Life with mpMRI versus diagnostic TURBT., secondaryOutcomes measure: Incidence of repeat TURBT., secondaryOutcomes measure: Diagnostic healthcare expenditure with mpMRI versus diagnostic TURBT, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Chao Family Comprehensive Cancer Center University of California, Irvine, city: Orange, state: California, zip: 92868, country: United States, contacts name: Nataliya Mar, MD, role: CONTACT, phone: 877-827-8839, email: ucstudy@uci.edu, geoPoint lat: 33.78779, lon: -117.85311, hasResults: False
protocolSection identificationModule nctId: NCT06335641, orgStudyIdInfo id: COOLHD24-CAN, briefTitle: Head COOLing in iscHemic Stroke Patients Undergoing EndovAscular Thrombectomy: a Feasibility and Safety stuDy, acronym: COOLHEAD-2-CAN, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2026-04-01, completionDateStruct date: 2026-04-01, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: University of Calgary, class: OTHER, descriptionModule briefSummary: This is an investigator-initiated, prospective, open-label, single-arm, non-randomized study to assess the safety and feasibility of external active conductive head cooling during endovascular thrombectomy procedures., conditionsModule conditions: Stroke, Acute, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: External active conductive head cooling, outcomesModule primaryOutcomes measure: Adherence to the intervention., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06335628, orgStudyIdInfo id: RCT: CTG-VCMX, briefTitle: Volumetric Dimensional Changes After Surgical Pontic Site Development Procedures With Connective Tissue Graft or Collagen Matrix, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2026-04, completionDateStruct date: 2029-04, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: University of Bern, class: OTHER, descriptionModule briefSummary: The aim of this research project is to compare two surgical procedures to improve soft tissue volume. Both procedures have already been validated, but despite their great clinical relevance, little data exists in the literature. With this study, the investigators aim to evaluate volumetric changes of connective tissue graft versus biomaterial (membrane). In addition, further clinical measurements will be taken and patient satisfaction will be assessed., conditionsModule conditions: Connective Tissue Graft, conditions: Volume Collagen Matrix Xenograft, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, enrollmentInfo count: 38, type: ESTIMATED, armsInterventionsModule interventions name: Geistlich Fibro-Gide®, outcomesModule primaryOutcomes measure: Volumetric dimensional changes, secondaryOutcomes measure: Clinical: PPD, secondaryOutcomes measure: Clinical BoP, secondaryOutcomes measure: Clinical: Suppuration, secondaryOutcomes measure: Clinical: Mucosa, secondaryOutcomes measure: Clinical: ktw, secondaryOutcomes measure: Clinical: Mobility, secondaryOutcomes measure: Clinical: Thickness, secondaryOutcomes measure: Clinical: Contributing factors, secondaryOutcomes measure: Patient-reported satisfaction, secondaryOutcomes measure: Patient-reported esthetics, secondaryOutcomes measure: Patient-reported discomfort, secondaryOutcomes measure: Patient-reported pain, secondaryOutcomes measure: Prosthetics Survival, secondaryOutcomes measure: Prosthetics Sucess, secondaryOutcomes measure: Prosthetics Complications, secondaryOutcomes measure: Prosthetics PES-WES, secondaryOutcomes measure: Prosthetics: Occlusal, secondaryOutcomes measure: Prosthetics: Interproximal, secondaryOutcomes measure: Radiographics BL, secondaryOutcomes measure: Radiographics PP, secondaryOutcomes measure: Radiographics distance, secondaryOutcomes measure: Radiographics Contacts, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Bern, city: Bern, zip: 3010, country: Switzerland, contacts name: Martin Schimmel, Prof., role: CONTACT, phone: +41316840630, email: martin.schimmel@unibe.ch, contacts name: Manrique Fonseca, Dr. med. dent., role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 46.94809, lon: 7.44744, hasResults: False
protocolSection identificationModule nctId: NCT06335615, orgStudyIdInfo id: FMG-5790_2023, briefTitle: A Brief Acceptance Intervention for Stress to Improve Students' Well-Being, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-11-27, primaryCompletionDateStruct date: 2023-12-19, completionDateStruct date: 2023-12-19, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: VU University of Amsterdam, class: OTHER, descriptionModule briefSummary: The goal of this randomized controlled trial is to test a brief psychological intervention that focusses on acceptance of stress in a student population. The main questions it aims to answer are:* Does this brief acceptance intervention increase the well-being of students in the short term?* By which mechanisms does this effect occur?* What are moderating factors of this effect?Half of the participants follow a one-hour intervention, which includes* psychoeducation and metaphors about stress and how acceptance can help to deal with it* experiential exercises* mindfulness meditation* mindfulness homework practiceStudents that receive the intervention will be compared to students that merely received psychoeducation about stress and acceptance to see if the intervention lead to larger increases in well-being., conditionsModule conditions: Stress, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 116, type: ACTUAL, armsInterventionsModule interventions name: Brief Acceptance Intervention, interventions name: Psychoeducation, outcomesModule primaryOutcomes measure: Psychological Well-Being, secondaryOutcomes measure: State Anxiety, secondaryOutcomes measure: Study Stress, secondaryOutcomes measure: Interoceptive awareness, secondaryOutcomes measure: Psychological Flexibility, eligibilityModule sex: ALL, minimumAge: 17 Years, maximumAge: 29 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: University of Amsterdam, city: Amsterdam, state: Noord-Holland, zip: 1018 WS, country: Netherlands, geoPoint lat: 52.37403, lon: 4.88969, hasResults: False
protocolSection identificationModule nctId: NCT06335602, orgStudyIdInfo id: 202301283A3, briefTitle: TCM for Post-operative Edema, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-30, primaryCompletionDateStruct date: 2025-09-30, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Chang Gung Memorial Hospital, class: OTHER, descriptionModule briefSummary: There are loads of research on knee surgery, including surgical methods, rehabilitation strategies, and complication prevention. Whether it is general surgery or endoscopic surgery, there may be postoperative joint swelling, which may last for several weeks depending on the patient's condition. Therefore, reducing swelling as soon as possible is important in post-operative treatment. Swelling of the knee joint may increase soft tissue tension, causing pain and discomfort, and affecting the range of motion and functional recovery of the joint. It may also affect wound healing and increase the risk of complications such as infection and thrombosis. Most clinical research related to traditional Chinese medicine focuses on reducing pain, and little attention is paid to reducing swelling, relatively. Nevertheless most relevant literatures discuss total knee replacement surgery.Cruciate ligament surgery is very common in sports medicine orthopedics. It is expected that ordinary patients get function recovery quickly after surgery, and athletes can return to play as soon as possible. This study is a prospective study, with partially double-blinded, randomized controlled study design. The investigators are aiming to TCM intervention for knee swelling after cruciate ligament surgery, and evaluation of postoperative swelling and functional improvement. TCM intervention methods are laser acupuncture and external application of herbal medicine., conditionsModule conditions: Anterior Cruciate Ligament Injuries, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: LASER acupuncture, outcomesModule primaryOutcomes measure: Leg girth measurement, secondaryOutcomes measure: VAS, secondaryOutcomes measure: WOMAC, secondaryOutcomes measure: Tegner score, eligibilityModule sex: MALE, minimumAge: 18 Years, maximumAge: 50 Years, stdAges: ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06335576, orgStudyIdInfo id: ZSGCproteomics, briefTitle: Establishment of Serum Proteomics Subtypes of Gastric Cancer and Its Clinical Application, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-31, primaryCompletionDateStruct date: 2026-10-31, completionDateStruct date: 2026-12-31, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Shanghai Zhongshan Hospital, class: OTHER, descriptionModule briefSummary: This study is a prospective, single-center, observational study aimed at detecting the status of serum protein profiles at key time points in gastric cancer patients receiving neoadjuvant therapy for advanced disease, and constructing a serum protein model for evaluating the efficacy of neoadjuvant therapy for gastric cancer. Subjects will receive neoadjuvant therapy (treatment regimen determined by the primary physician, limited to systemic therapy, with options including immune checkpoint inhibitor-based regimens and non-immune checkpoint inhibitor-based regimens). After four cycles of treatment, the efficacy will be assessed. Patients eligible for R0 resection will undergo D2 radical surgery regardless of tumor regression, while those ineligible for R0 resection will enter the palliative treatment phase (Note: Subjects are all patients who require neoadjuvant therapy even if they do not participate in this clinical study). Patients will receive regular follow-up evaluations for metastasis/recurrence and survival until tumor recurrence/progression or the last known date of patient survival (Note: Regular follow-up in this study follows the frequency of routine clinical follow-ups). The primary endpoint is progression-free survival (PFS), and the secondary endpoint is pathological response rate (based on Becker tumor regression grading, with residual tumor less than 50% considered effective preoperative treatment).Peripheral venous blood samples will be collected before the start of neoadjuvant therapy (blood sampling point 1 - baseline) and before surgery after neoadjuvant therapy (blood sampling point 2 - post-treatment). Approximately 3 ml of blood will be collected each time, and about 1.5 ml of serum will be obtained after processing. Serum protein profiling will be conducted to assess the expression of protein profiles at these treatment time points., conditionsModule conditions: Gastric Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 89, type: ESTIMATED, armsInterventionsModule interventions name: This study is a single-arm and observational study with no intervention., outcomesModule primaryOutcomes measure: C-index, secondaryOutcomes measure: Sensitivity and specificity of model, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06335563, orgStudyIdInfo id: STAR009, briefTitle: Augmented Reality Navigation Versus Traditional CT Guidance for Preoperative Localization of Pulmonary Nodules, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-14, primaryCompletionDateStruct date: 2024-12-01, completionDateStruct date: 2024-12-01, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-04-12, sponsorCollaboratorsModule leadSponsor name: Shanghai Pulmonary Hospital, Shanghai, China, class: OTHER, descriptionModule briefSummary: This study aims to conduct a large-sample randomized controlled clinical trial, using traditional CT-guided thoracic puncture localization as a comparison, to explore the accuracy, safety and clinical advantages of Intelligent AR glasses in assisting preoperative localizing of small pulmonary nodules., conditionsModule conditions: Pulmonary Nodule, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: AR glasses-assisted puncture localizing group versus CT-guided conventional pulmonary nodule puncture localizing group, primaryPurpose: TREATMENT, maskingInfo masking: NONE, maskingDescription: no masking, enrollmentInfo count: 166, type: ESTIMATED, armsInterventionsModule interventions name: AR glasses-assisted pulmonary nodule puncture localization, interventions name: CT-guided pulmonary nodule puncture localization, outcomesModule primaryOutcomes measure: Accuracy of puncture localization of pulmonary nodules, secondaryOutcomes measure: Success rate of puncture localization of pulmonary nodules, secondaryOutcomes measure: Adjust the number of needle punctures, secondaryOutcomes measure: Operating time, secondaryOutcomes measure: Radiation dose, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Shanghai Pulmonary Hospital, status: RECRUITING, city: Shanghai, state: Shanghai, zip: 200433, country: China, contacts name: Shenghao Huang, role: CONTACT, email: huangshplus5@163.com, geoPoint lat: 31.22222, lon: 121.45806, hasResults: False
protocolSection identificationModule nctId: NCT06335524, orgStudyIdInfo id: IRB-300012718, briefTitle: Infant-Maternal Partnership and Cognitive Training Study for Preterm Infants, acronym: IMPACT, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09, primaryCompletionDateStruct date: 2026-08, completionDateStruct date: 2028-08, studyFirstPostDateStruct date: 2024-03-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: University of Alabama at Birmingham, class: OTHER, descriptionModule briefSummary: This study will test the hypothesis that in preterm infants a caregiver-implemented early developmental intervention (EDI) using finger puppets to develop joint attention and encourage interactive communication with routine EDI care including Bookworm training compared with routine EDI care including Bookworm training alone will increase the Ages and Stages Questionnaire® score at 12 months corrected age., conditionsModule conditions: Child Development, conditions: Infant Development, conditions: Infant, Premature, Diseases, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 188, type: ESTIMATED, armsInterventionsModule interventions name: Finger puppet, interventions name: Bookworm reading intervention training and routine EDI care., outcomesModule primaryOutcomes measure: ASQ-3 scores, secondaryOutcomes measure: ASQ-3 scores, secondaryOutcomes measure: ASQ scores below -2SD, secondaryOutcomes measure: ASQ scores below -2SD, secondaryOutcomes measure: ASQ scores below -1SD, secondaryOutcomes measure: ASQ scores below -1SD, secondaryOutcomes measure: ASQ-SE2 scores, secondaryOutcomes measure: ASQ-SE2 scores, secondaryOutcomes measure: Severe neurodevelopmental impairment, secondaryOutcomes measure: Moderate or severe neurodevelopmental impairment, secondaryOutcomes measure: Cognitive Composite Score on BSID-IV, secondaryOutcomes measure: Language Composite Score on BSID-IV, secondaryOutcomes measure: Motor Composite Score on BSID-IV, secondaryOutcomes measure: Edinburgh Postnatal Depression Scale, secondaryOutcomes measure: MCHAT score, eligibilityModule sex: ALL, minimumAge: 1 Day, maximumAge: 17 Weeks, stdAges: CHILD, contactsLocationsModule, hasResults: False