protocolSection identificationModule nctId: NCT06362382, orgStudyIdInfo id: 2024-zxm-01, briefTitle: Mobile Internet-based Remote Home Rehabilitation Improves Prognostic Function and Life Quality in Pulmonary Hypertension, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-22, primaryCompletionDateStruct date: 2026-04-22, completionDateStruct date: 2026-05-01, studyFirstPostDateStruct date: 2024-04-12, lastUpdatePostDateStruct date: 2024-04-12, sponsorCollaboratorsModule leadSponsor name: China-Japan Friendship Hospital, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to learn the effectiveness of remote home-based exercise rehabilitation using mobile Internet technology for patients with pulmonary hypertension，especically providing early and mid-term results of its effectiveness. The main questions it aims to answer are:Dose tele-rehabilitation training improves prognostic function and quality of life in patients with pulmonary hypertension？ Researchers will compare tele-rehabilitation training group to a control group (receive health propaganda and education, and then follow their daily routine after discharge from the hospital) to see if tele-rehabilitation training works to improve prognosis.Participants will:During their stay in the hospital, the patients of tele-rehabilitation training group were accompanied by a rehabilitation trainer and a psychotherapist for a complete cycle of (7 days ± 3 days 1 week/times) standardized training. The scheme of rehabilitation is impedance training. A specialized professional team including cardiologists, rehabilitation trainers, psychotherapists and radiologists were involved. After discharge from the hospital, patients in the rehabilitation group underwent 3-5 weekly daily training sessions and intensive supervision and management by the online community at least once a week.Visit the clinic at the 3rd month of the study. Extended follow-up up to 6 months may be considered if patients are cooperative and could complete the training program in the first 3 months., conditionsModule conditions: Pulmonary Hypertension, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: tele-rehabilitation training, interventions name: health propaganda and education, outcomesModule primaryOutcomes measure: changes in 6MWD after 3 months, primaryOutcomes measure: changes in muscle mass after 3 months, secondaryOutcomes measure: peak VO2, secondaryOutcomes measure: VO2peak%, secondaryOutcomes measure: VE/VCO2 slope, secondaryOutcomes measure: PET CO2, secondaryOutcomes measure: Changes in muscle mass evaluated by CT, secondaryOutcomes measure: Changes in grip strength, secondaryOutcomes measure: the time for 5 sit-to-stand test, secondaryOutcomes measure: Quality of life measured by SF-36 after 3 months, secondaryOutcomes measure: Quality of life measured by SF-36 after 6 months, secondaryOutcomes measure: Quality of life measured by emPHasis-10 after 3 months, secondaryOutcomes measure: Quality of life measured by emPHasis-10 after 6 months, secondaryOutcomes measure: Changes in WHO Cardiac Function Classification, secondaryOutcomes measure: Change in NT-proBNP, secondaryOutcomes measure: Change in TAPSE by cardiac doppler ultrasound, secondaryOutcomes measure: Changes in hemodynamic indice after 6 months, secondaryOutcomes measure: Changes in sleep quality score after 3 months, secondaryOutcomes measure: Changes in sleep quality score after 6 months, secondaryOutcomes measure: Changes in psychosocial score after 3 months, secondaryOutcomes measure: Changes in psychosocial score after 6 months, secondaryOutcomes measure: All-cause mortality in 3 months, secondaryOutcomes measure: All-cause mortality in 6 months, secondaryOutcomes measure: The occurrence rate of primary events in pulmonary hypertension in 3 months, secondaryOutcomes measure: The occurrence rate of primary events in pulmonary hypertension in 6 months, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Fuwai Hospital, city: Beijing, state: Beijing, zip: 100037, country: China, contacts name: Xiaoming Zhou, MD, role: CONTACT, phone: +86 88396992, email: zhouxmcmu@163.com, contacts name: Xiaoming Zhou, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 39.9075, lon: 116.39723, hasResults: False