hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06356428, orgStudyIdInfo id: KARYÖN-DR, briefTitle: Psychometric Properties and Cross-cultural Adaptation of the Turkish Version of Physcian Attitudes Toward Cardiac Rehabilitation and Referral Scale-Revised (PACRR-R), statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-13, primaryCompletionDateStruct date: 2025-05-13, completionDateStruct date: 2025-08-13, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-15, sponsorCollaboratorsModule leadSponsor name: Karamanoğlu Mehmetbey University, class: OTHER, descriptionModule briefSummary: Research has reported that the reasons for low implementation of CR are multifactorial at the health system, physician and patient levels. It has also been found that patients are more likely to initiate CR if physicians strongly and positively promote the importance of CR participation. Unfortunately, there are insufficient and ineffective data on CR, referral to CR and both clinical and cost-effectiveness outcomes of CR in Turkey. In this context, it is important to examine more objectively from the perspective of physicians who play a key role in referring patients to CR. However, in our country, there is no relatively objective measurement tool to evaluate physicians' attitudes towards CR. Therefore, this study aims to adapt the original "Physician Attitudes towards Cardiac Rehabilitation and Referral Scale-Revised (PACRR-R)" into Turkish and to examine its psychometric properties., conditionsModule conditions: Physician's Role, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Physcian Attitudes toward Cardiac Rehabilitation and Referral Scale-Revised (PACRR-R), outcomesModule primaryOutcomes measure: Physician Attitudes toward Cardiac Rehabilitation and Referral (PACRR)-Revised Scale Score, eligibilityModule sex: ALL, minimumAge: 25 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06356415, orgStudyIdInfo id: Dex Dex in infraclavicular, briefTitle: Infraclavicular Brachial Plexus Block With Bupivacaine Alone or With Both Dexmedetomidine and Dexamethasone, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2024-08-30, completionDateStruct date: 2024-09-30, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Suez Canal University, class: OTHER, descriptionModule briefSummary: Upper-extremity regional anesthetic techniques, using brachial plexus blockade, have been shown to reduce adverse effects related to opioid administration, improve patient satisfaction, and provide significantly improved analgesia immediately following these surgeries. Many medications have been investigated to extend and enhance long-acting local anesthetics' (LA) analgesic effects. Currently, dexamethasone and dexmedetomidine have been studied, looking for an optimal long-lasting single-shot nerve block. In general, adjuvants have been used in peripheral nerve blocks to accelerate onset, decrease plasmatic absorption and secondary toxic effects, and prolong the block effects., conditionsModule conditions: Upper Extremity Injury, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: The sealed-envelope technique will be used. An assistant who is not involved in patient care will make and combine bupivacaine, whether it contains adjuvants or not. Thus, all patients, operators, and outcome assessors remain blinded to the nature of the perineural adjuvant, whoMasked: PARTICIPANT, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Bupivacaine injection, interventions name: Bupivacaine+ Dexamethasone+ Dexmedetomidine, outcomesModule primaryOutcomes measure: Onset of sensory block, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06356402, orgStudyIdInfo id: 8510224SMCPD, briefTitle: An Investigation of the Efficacy of OHEM for Improving Oral Hygiene in Children, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2024-08, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Ziauddin University, class: OTHER, collaborators name: Universiti Sains Malaysia, descriptionModule briefSummary: This pilot study evaluates the feasibility of conducting a larger Randomized Controlled Trial to compare three oral health education delivery methods to a control group. Except for the control group, mothers in the three intervention groups will receive the same oral health education based on the OHEM module but differ in the delivery methods, namely lecture, exhibition, and demonstration. All groups will receive a booklet and oral hygiene kits and be instructed to educate their children at home. Pre- and post-intervention assessments include the satisfaction of participants, the researchers' evaluation and cost of the trial, oral hygiene status, and the knowledge of the parents and children., conditionsModule conditions: Dental Plaque, conditions: Gingivitis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 540, type: ESTIMATED, armsInterventionsModule interventions name: Oral Health Educational Module for Mothers (OHEM) lecture, interventions name: Oral Health Educational Module for Mothers (OHEM) exhibition, interventions name: Oral Health Educational Module for Mothers (OHEM) demonstration, outcomesModule primaryOutcomes measure: Satisfaction of participants:, primaryOutcomes measure: Recruitment and participation of participants in the study, primaryOutcomes measure: Cost of the trial, secondaryOutcomes measure: Dental plaque scores, secondaryOutcomes measure: Gingival scores, secondaryOutcomes measure: Oral health KAP scores, secondaryOutcomes measure: Oral health behaviors, secondaryOutcomes measure: Oral health-related quality of life using Oral health impact profile-14, eligibilityModule sex: ALL, minimumAge: 12 Years, maximumAge: 40 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Primary Healthcare Center Gulshan-e-Sikandarabad Shireen Jinnah Colony, city: Karachi, country: Pakistan, contacts name: Sidra Mohiuddin, MDS, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 24.8608, lon: 67.0104, hasResults: False
protocolSection identificationModule nctId: NCT06356389, orgStudyIdInfo id: JX11502MA-Ib-II, briefTitle: A Clinical Trial to Evaluate Safety, Tolerance and Pharmacokinetics of JX11502MA Capsule in Patients With Schizophrenia., statusModule overallStatus: COMPLETED, startDateStruct date: 2022-03-02, primaryCompletionDateStruct date: 2022-12-27, completionDateStruct date: 2023-01-28, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Zhejiang Jingxin Pharmaceutical Co., Ltd., class: INDUSTRY, collaborators name: Shanghai Mental Health Center, descriptionModule briefSummary: A multicenter, randomized, double-blind, placebo-controlled, dose-increasing phase Ib/II clinical trial to evaluate the safety, tolerance and pharmacokinetic characteristics of JX11502MA capsules administered multiple times in patients with schizophrenia, conditionsModule conditions: Schizophrenia, designModule studyType: INTERVENTIONAL, phases: PHASE1, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: Double-Blind, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 60, type: ACTUAL, armsInterventionsModule interventions name: JX11502MA, interventions name: Placebo, outcomesModule primaryOutcomes measure: Incidence of treatment-emergent adverse events (TEAEs), secondaryOutcomes measure: Change From Baseline in Positive and Negative Syndrome Scale (PANSS) Total Score at Day 28, secondaryOutcomes measure: Change From Baseline in Positive and Negative Syndrome Scale (PANSS) Positive Score at Day 28, secondaryOutcomes measure: Change From Baseline in Positive and Negative Syndrome Scale (PANSS) Negative Score at Day 28, secondaryOutcomes measure: Change From Baseline in Clinical Global Impression - Severity (CGI-S) Score at Day 28, secondaryOutcomes measure: Tmax, secondaryOutcomes measure: Css_min, secondaryOutcomes measure: Css_max, secondaryOutcomes measure: Css_av, secondaryOutcomes measure: AUC0-t,ss, secondaryOutcomes measure: AUC0-∞,ss, secondaryOutcomes measure: AUCtau,ss, secondaryOutcomes measure: t1/2, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule locations facility: Shanghai Mental Health Center, city: Shanghai, state: Shanghai, zip: 201109, country: China, geoPoint lat: 31.22222, lon: 121.45806, hasResults: False
protocolSection identificationModule nctId: NCT06356376, orgStudyIdInfo id: UAarhus_AGK_MNG_2, briefTitle: The Effects of Pain and Pain Relief on Peripheral Nerve Excitability, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-12-20, primaryCompletionDateStruct date: 2024-04-30, completionDateStruct date: 2024-04-30, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: University of Aarhus, class: OTHER, collaborators name: Lundbeck Foundation, descriptionModule briefSummary: This study will assess changes in nerve excitability of C-fibers, and changes in sympathetic or parasympathetic tone, when the subject experiences pain and pain relief.The investigators will continuously measure blood pressure, heart rate, respiration rate, gastric motility, sympathetic skin response and C-fiber excitability while using thermal stimuli before and after an analgesic., conditionsModule conditions: Analgesia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Heat Stimulation, outcomesModule primaryOutcomes measure: C-fiber excitability, secondaryOutcomes measure: Action potential duration (ms), secondaryOutcomes measure: Action potential amplitude (V), secondaryOutcomes measure: Heart-rate variability (ms), secondaryOutcomes measure: Blood pressure variability (mmHg), secondaryOutcomes measure: Sympathetic Skin Response (V), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Danish Pain Research Center, status: RECRUITING, city: Aarhus N, zip: 8200, country: Denmark, contacts name: Alexander G Kristensen, MD,PhD, role: CONTACT, phone: +45 93 52 28 64, email: alexgramm@clin.au.dk, geoPoint lat: 56.15674, lon: 10.21076, hasResults: False
protocolSection identificationModule nctId: NCT06356363, orgStudyIdInfo id: 2023_RIPH_005_OncoPREMs, briefTitle: Development of a Questionnaire on Patients' Perception of Their Oncology Care Pathway (Onco-PREMs), acronym: OncoPREMs, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2025-11-01, completionDateStruct date: 2025-11-01, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Institut Jean-Godinot, class: OTHER, collaborators name: Université de Reims Champagne-Ardenne, descriptionModule briefSummary: Healthcare systems are evolving, giving increasing prominence to the patient-centered model, accompanied by objective and perceived outcomes.PREMs (Patient Reported Experience Measures) are used to assess how patients feel about their experience of care. PREMs enable patients to take an active role in their own care, and enable healthcare establishments to identify areas for improvement that can be incorporated into their quality processes.In oncology, the collection of patient-perceived quality regarding their care pathway would enable better coordination of their care. While a few initiatives have emerged in the field of PREMs, the development of a reliable questionnaire assessing patient perception of their care pathway in oncology remains a challenge., conditionsModule conditions: Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 500, type: ESTIMATED, armsInterventionsModule interventions name: Data collection, outcomesModule primaryOutcomes measure: Psychometric validation, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06356350, orgStudyIdInfo id: IUC_jia_scoliosis_gait, briefTitle: Exercise Programs on Gait in Children With Scoliosis Diagnosed JIA, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-10-01, completionDateStruct date: 2024-11-01, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-19, sponsorCollaboratorsModule leadSponsor name: Istanbul University - Cerrahpasa (IUC), class: OTHER, descriptionModule briefSummary: Juvenile Idiopathic Arthritis (JIA) is one of the common chronic diseases in childhood. Problems such as weakness or pain may occur in JIA, especially in the joints and the muscles around the trunk (1). These conditions may lead to abnormal displacement of the center of gravity, deterioration of biomechanics, and muscle imbalance in children with JIA (2, 3). All these situations can lead to scoliosis, which we often encounter in children with JIA. Current studies describing various 3-dimension (3D) exercise methods (SEAS, Schroth, Dobomed, BSPTS, Side-shift, Lyon, etc.) effective on scoliosis (4). However, no study was found in the literature that searching the effects of these exercise methods on gait parameters in children with scoliosis diagnosed JIA., conditionsModule conditions: Scoliosis Idiopathic, conditions: Juvenile Idiopathic Arthritis, conditions: Gait, Frontal, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Conventional exercises, interventions name: 3D exercises, outcomesModule primaryOutcomes measure: ATR, primaryOutcomes measure: Cobb angle, primaryOutcomes measure: Maximum Loading, primaryOutcomes measure: Center of mass displacement, primaryOutcomes measure: Walking speed, eligibilityModule sex: ALL, minimumAge: 6 Years, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Istanbul University-Cerrahpasa, status: RECRUITING, city: Istanbul, country: Turkey, contacts name: Gökçe Leblebici, role: CONTACT, phone: 05397395718, email: leblebicigokce@gmail.com, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06356337, orgStudyIdInfo id: STUDY-22-01199, briefTitle: A Light Exposure Tracker Designed to Improve Circadian Rhythms - Aim 1, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-22, primaryCompletionDateStruct date: 2024-08-31, completionDateStruct date: 2025-08-31, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Icahn School of Medicine at Mount Sinai, class: OTHER, descriptionModule briefSummary: The purpose of this research study is to investigate the relationship between light and circadian rhythms. Twenty healthy older adults will be recruited to participate in a randomized, cross-over study, where an active lighting intervention designed to maintain entrainment and a control intervention designed not to entrain will be tested., conditionsModule conditions: Alzheimer's Disease, conditions: Mild Cognitive Impairment, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: Light goggles, interventions name: Orange glasses, outcomesModule primaryOutcomes measure: Saliva samples for melatonin levels, secondaryOutcomes measure: Light exposure using the Speck, secondaryOutcomes measure: Sleep time using actigraphy, eligibilityModule sex: ALL, minimumAge: 55 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Light and Health Research Center, status: RECRUITING, city: Menands, state: New York, zip: 12204, country: United States, contacts name: Barbara Plitnick, role: CONTACT, phone: 518-242-4603, email: barbara.plitnick@mountsinai.org, contacts name: Mariana Figueiro, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 42.69202, lon: -73.72456, hasResults: False
protocolSection identificationModule nctId: NCT06356324, orgStudyIdInfo id: 2021-13347, briefTitle: The Effects of Music and Television on Intraoperative Hypertensive Events in Cataract Surgery, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-10-18, primaryCompletionDateStruct date: 2024-01-31, completionDateStruct date: 2024-04-01, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Montefiore Medical Center, class: OTHER, descriptionModule briefSummary: This study investigates whether television viewing or music listening can reduce pre-operative anxiety and improve surgical outcomes for patients undergoing cataract surgery. It aims to determine the effectiveness of these interventions compared to a control group and assess their impact on physiological markers of anxiety as well as the incidence of intra-operative hypertensive events.The key questions that are to be answered are:1. Does watching television before cataract surgery decrease intraoperative hypertensive events and/or pre-operative anxiety in patients?2. Does listening to music before cataract surgery decrease intraoperative hypertensive events and/or pre-operative anxiety in patients?, conditionsModule conditions: Anxiety, conditions: Intraoperative Hypertension, conditions: Cataract, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Participants assigned to one of three groups: music listening, tv viewing, or control (waiting with ambient noise), primaryPurpose: PREVENTION, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, enrollmentInfo count: 650, type: ACTUAL, armsInterventionsModule interventions name: Music Intervention, interventions name: Television Intervention, outcomesModule primaryOutcomes measure: Intraoperative hypertensive event, secondaryOutcomes measure: Change in VAS-A measurements for Anxiety, secondaryOutcomes measure: Change in Heart Rate measurements for Anxiety, secondaryOutcomes measure: Change in Blood pressure measurements for Anxiety, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Montefiore Medical Center, city: New York, state: New York, zip: 10467, country: United States, geoPoint lat: 40.71427, lon: -74.00597, hasResults: False
protocolSection identificationModule nctId: NCT06356311, orgStudyIdInfo id: 2870-015, secondaryIdInfos id: 2023-505423-31, type: REGISTRY, domain: EU CT, secondaryIdInfos id: U1111-1291-7109, type: OTHER, domain: UTN, secondaryIdInfos id: MK-2870-015, type: OTHER, domain: Merck Id, briefTitle: A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015), statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-08, primaryCompletionDateStruct date: 2027-01-04, completionDateStruct date: 2028-05-05, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: Merck Sharp & Dohme LLC, class: INDUSTRY, descriptionModule briefSummary: This study will compare how safe and effective sacituzumab tirumotecan is versus the treatment of physician's choice (TPC) in participants with advanced/metastatic gastroesophageal adenocarcinoma. The primary hypothesis of this study is sacituzumab tirumotecan is superior to TPC with respect to Overall Survival (OS)., conditionsModule conditions: Gastroesophageal Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 450, type: ESTIMATED, armsInterventionsModule interventions name: Sacituzumab tirumotecan, interventions name: Trifluridine-Tipiracil, interventions name: Irinotecan, interventions name: Paclitaxel, interventions name: Docetaxel, outcomesModule primaryOutcomes measure: Overall Survival (OS), secondaryOutcomes measure: Progression-free survival (PFS), secondaryOutcomes measure: Objective Response Rate (ORR), secondaryOutcomes measure: Duration of Response (DOR), secondaryOutcomes measure: Number of Participants Who Experience an Adverse Event (AE), secondaryOutcomes measure: Number of Participants Who Discontinue Study Intervention Due to an AE, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False