hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06372106, orgStudyIdInfo id: MA_PM_Mountain_2022_11496, briefTitle: Project Mountain - Comparing SpO2 and SaO2 for Accuracy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Philips Clinical & Medical Affairs Global, class: INDUSTRY, descriptionModule briefSummary: The main goal of this study is to look at the performance of the neonatal, infant, and pediatric Philips SpO2 sensors with the Philips FAST Pulse Oximetry technology. Oxygen saturation measurements (SpO2) will be obtained via pulse oximetry and invasive arterial oxygen measurements (SaO2) will be obtained via arterial blood samples as part of your clinical care and assessed by co-oximetry. The study will aim to enroll a diverse population to help us understand the impact of skin pigmentation., conditionsModule conditions: SpO2, conditions: Nasal Alar Collapse, Bilateral, conditions: Oxygen, conditions: Measurement, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: OTHER, enrollmentInfo count: 560, type: ESTIMATED, armsInterventionsModule interventions name: SaO2 Sampling, outcomesModule primaryOutcomes measure: To observed accuracy expressed in ARMS of SpO2 measurements obtained from neonatal, infant, and pediatric sensors with the Philips FAST Pulse Oximetry technology within the range of 70-100% in comparison to the SaO2 as ground truth., secondaryOutcomes measure: Secondary Endpoint -Non-disparate bias with consideration to skin pigmentation for each neonatal, infant, and pediatric SpO2 sensor under test with the Philips FAST Pulse Oximetry technology., secondaryOutcomes measure: Secondary Endpoint- Proportion of paired SaO2 and SpO2 readings in which occult hypoxemia (i.e., SaO2 <88% with SpO2 ≥92%) is identified among patients within the broad categories of light, medium, and dark pigmentation., eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06372093, orgStudyIdInfo id: PMH 2/11AII, briefTitle: Evaluation of Bilirubin Measurements in Newborns From Smartphone Digital Images in a Population in Botswana, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-03-16, primaryCompletionDateStruct date: 2024-02-26, completionDateStruct date: 2024-02-26, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Picterus AS, class: INDUSTRY, collaborators name: University of Copenhagen, collaborators name: University of Botswana, descriptionModule briefSummary: The general objective of this study is to evaluate the accuracy of a novel smartphone application for jaundice screening (Picterus Jaundice Pro) in a population with high melanin content in the skin.The specific objectives for this study are:i. To assess the correlation between bilirubin level measurements obtained by Picterus Jaundice Pro with Total Serum Bilirubin (TSB), and TcB, in newborns with high melanin content in the skin.ii. To determine the accuracy of Picterus Jaundice Pro in newborns with high melanin content in the skin., conditionsModule conditions: Jaundice, Neonatal, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: SCREENING, maskingInfo masking: NONE, enrollmentInfo count: 172, type: ACTUAL, armsInterventionsModule interventions name: Picterus Jaundice Pro, outcomesModule primaryOutcomes measure: Enable high qualitative estimation of bilirubin levels in the blood of newborns in a population in Botswana using Picterus JP., secondaryOutcomes measure: Correlation of bilirubin levels obtained by Picterus JP with Tsb and TcB, secondaryOutcomes measure: Sensitivity and specificity of Picterus JP to detect jaundice in newborns with high melanin content in the skin, eligibilityModule sex: ALL, minimumAge: 1 Day, maximumAge: 14 Days, stdAges: CHILD, contactsLocationsModule locations facility: Princess Marina Hospital, city: Gaborone, country: Botswana, geoPoint lat: -24.65451, lon: 25.90859, hasResults: False
protocolSection identificationModule nctId: NCT06372067, orgStudyIdInfo id: 17378, briefTitle: IM Screw vs. K-wire Fixation of Proximal/Middle Phalanx Fractures, acronym: HANDFIX, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-07-01, primaryCompletionDateStruct date: 2025-12-31, completionDateStruct date: 2026-03-01, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: McMaster University, class: OTHER, descriptionModule briefSummary: When people break their fingers, sometimes surgery is needed to align the bones to heal them properly. There are different ways to fix broken bones in hands, such as plates, pins, or screws. Each method has pros and cons; fixing a broken bone with plates is usually a larger surgery with more cutting but holds the bones very securely. Pins require little to no cutting but the patient needs to immobilize their hand for a few weeks afterwards. Screws are a newer method of fixing broken fingers that requires little cutting and also holds the bones securely. The goal of this study is to compare the effectiveness of using pins versus screws in surgery for broken fingers. The investigators are studying whether using screws leads to better hand function, patient satisfaction, and quicker return to work., conditionsModule conditions: Hand; Fracture, Phalanx, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized, open-label, pilot randomized controlled trial, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: By nature of the interventions in this study, blinding will not be possible for the surgeon or the patient post-operatively., whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 34, type: ESTIMATED, armsInterventionsModule interventions name: Intramedullary screw, interventions name: Kirschner wire, outcomesModule primaryOutcomes measure: Percentage of Patient Eligibility - Study Feasibility, primaryOutcomes measure: Recruitment rate - Study Feasibility, primaryOutcomes measure: Crossover rate - Study Feasibility, primaryOutcomes measure: Compliance with intervention rate - Study Feasibility, primaryOutcomes measure: Patient retention rate - Study Feasibility, secondaryOutcomes measure: Disability of the Arm, Shoulder, and Hand, secondaryOutcomes measure: Range of motion, secondaryOutcomes measure: Grip strength, secondaryOutcomes measure: Return to work, secondaryOutcomes measure: Complications/adverse events, secondaryOutcomes measure: Postoperative pain (visual analogue scale), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06372015, orgStudyIdInfo id: RC2023-24, briefTitle: Changes in the Lipidomic, Immunological and miRNA Profile in Patients Undergoing a Dietary Program or Bariatric Surgery, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2025-06-01, completionDateStruct date: 2026-06-01, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis, class: OTHER, collaborators name: Notarnicola Maria, collaborators name: Cozzolongo Raffaele, collaborators name: Shahini Endrit, collaborators name: De Pergola Giovanni, collaborators name: Lippolis Giuseppe, descriptionModule briefSummary: Obesity is a chronic disease characterized phenotypically by an increase in body weight (BMI\>30 kg/m2) and by a series of associated pathologies, such as hypertension, diabetes, hepatic steatosis.The association of these pathologies compromises the patient's survival and quality of life. The multifactorial origin of obesity makes its etiopathology difficult to manage. It is often possible to follow only one therapeutic strategy, especially after the so-called standard treatments, such as dietary intervention and physical activity, have not brought benefit to the patient. In these cases, an appropriate treatment for the patient to enjoy significant weight loss is bariatric surgery.Bariatric surgery refers to all those interventions aimed at reducing weight in those suffering from obesity, and treating the diseases associated with it.Among the different types of bariatric surgery, the techniques most used in common clinical practice are intragastric balloons, gastric by pass (RYGB) and sleeve gastrectomy.The choice of the surgeon, assisted by the multidisciplinary team, is binding in the choice of the type of operation to which the patient will be subjected., conditionsModule conditions: Obesity, conditions: Liver Disease Parenchymal, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: OTHER, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Nutritional Approach, interventions name: Surgery Approach, outcomesModule primaryOutcomes measure: Variation of lipidomic parameters, primaryOutcomes measure: The effect of intervention on routine blood chemistry parameters, relating to NAFLD and fibrosis, primaryOutcomes measure: Variation in the microRNA profile, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: IRCCS "Saverio de Bellis", city: Castellana Grotte, state: Bari, zip: 70013, country: Italy, contacts name: Rossella Donghia, Biologyst, role: CONTACT, phone: 0804994652, email: rossella.donghia@irccsdebellis.it, geoPoint lat: 40.88643, lon: 17.16549, hasResults: False
protocolSection identificationModule nctId: NCT06371937, orgStudyIdInfo id: 120687, briefTitle: iPSC Biobank of Biomarkers Diversity in Cardiovascular Disease, acronym: INFERENCE, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2033-06-30, completionDateStruct date: 2033-06-30, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-25, sponsorCollaboratorsModule leadSponsor name: Lawson Health Research Institute, class: OTHER, collaborators name: Greenstone Biosciences, Inc., descriptionModule briefSummary: The Investigators will create a clinical database and a Biobank of stem cells derived from the blood of participants with cardiovascular disease. The Investigators will recruit participants from diverse racial and ethnic backgrounds with equal representation from both sexes. The Investigators expect to create stem cells and analyze the blood for protein biomarkers and genetic causes of cardiovascular disease. The stem cell biobank and clinical data will be a powerful tool for studying cardiovascular disease., conditionsModule conditions: Cardiovascular Diseases, conditions: Arrythmia, conditions: Cardiomyopathies, conditions: Heart Failure, conditions: Cerebrovascular Accident, conditions: Congenital Heart Disease, conditions: Cardiometabolic Syndrome, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: REDCap Database, primaryOutcomes measure: Induced pluripotent stem cell (iPSC) Biobank, primaryOutcomes measure: Differentiation into Cardiovascular lineages, primaryOutcomes measure: Molecular profiling of participants, primaryOutcomes measure: Bioinformatics analysis, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06371898, orgStudyIdInfo id: 29BRC24.0088 - MORDIGO, briefTitle: Comparison of MORbidity of Submucosal DIssection Resection of Giant cOlon Lesions Versus Surgery: a National Multicenter Study (MORDIGO), acronym: MORDIGO, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-03-18, primaryCompletionDateStruct date: 2025-06-17, completionDateStruct date: 2025-06-17, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: University Hospital, Brest, class: OTHER, descriptionModule briefSummary: Propose a one-piece endoscopic resection such as endoscopic submucosal dissection (ESD) rather than surgery for benign lesions and superficial T1 cancers colorectal cancers offers comparable efficacy with better tolerability. This approach is all the more in the rectum, even for giant lesions lesions (over 8cm), as rectal surgery is particularly morbid, with particularly morbid, with a functional impact that can impact, whereas rectal ESD is less prone to complications fewer complications than in the colon. Colonic ESD for giant lesions is a longer and more morbid more time-consuming and morbid than for smaller lesions, the question of colonic surgery in this indication. this indication. In order to compare the morbidity data of patients of giant lesions with those of colectomy, a control group colectomy, a surgical control group will be set up, including patients including patients having undergone surgery for in situ T1 or T2 in situ colon cancer. Surgical resections of resection of benign lesions is generally not indicated not indicated and would not provide the necessary necessary for a comparison. T3 and T4 lesions with their own their own morbidity will be excluded., conditionsModule conditions: Colonic Neoplasms, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: RETROSPECTIVE, enrollmentInfo count: 500, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: 30 days severe morbidity, secondaryOutcomes measure: morbidity of ESD group, secondaryOutcomes measure: comparison of morbidity in both groups, secondaryOutcomes measure: reintervention, secondaryOutcomes measure: stomia, secondaryOutcomes measure: length of hospital stay, secondaryOutcomes measure: readmission, secondaryOutcomes measure: mortality, secondaryOutcomes measure: risk factors for morbidity, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Chu Brest, city: Brest, zip: 29609, country: France, geoPoint lat: 48.3903, lon: -4.48628, hasResults: False
protocolSection identificationModule nctId: NCT06371885, orgStudyIdInfo id: P.T.REC/012/004646, briefTitle: Shock Wave on Pillar Pain After Carpal Tunnel Release in Hand Burn, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-08-10, primaryCompletionDateStruct date: 2024-05-30, completionDateStruct date: 2024-06-28, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: "In burn cases, the reported causes of CTS are increased volume of carpal tunnel content due to edema and synovitis, wrist hyperextension, tight dressing, fibrosis, and direct burn to the nerve. There are two types of pain that occur in the palm of the hand after carpal tunnel surgery: incisional pain and pillar pain. The incision pain typically only lasts for a few days or weeks after surgery, while the pillar pain occurs on the sides of the incision in the thicker parts of the palm, called the thenar and hypothenar eminences. This is where the transverse ligament attaches to the carpal bones, forming the carpal tunnel.So, in this study we will find out if shock wave therapy has therapeutic effect on pillar pain after carpal tunnel release in hand burn., conditionsModule conditions: Hand Burn, conditions: Carpal Tunnel Syndrome, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Interventional (clinical trial), primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: Double mask for both groups (participant), whoMasked: PARTICIPANT, enrollmentInfo count: 52, type: ACTUAL, armsInterventionsModule interventions name: shock wave therapy, interventions name: traditional physical therapy, outcomesModule primaryOutcomes measure: Visual Analog Scale, primaryOutcomes measure: Hand held dynamometer, secondaryOutcomes measure: Michigan hand out Comes questionnaire, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 35 Years, stdAges: ADULT, contactsLocationsModule locations facility: Shaimaa Mohamed Ahmed El Sayeh, city: Cairo, state: New Cairo, zip: 02, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06371872, orgStudyIdInfo id: 2024-A00173-44, briefTitle: French Cohort of Patients With Rotator Cuff Lesions, acronym: PRO-CUFF, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2035-12, completionDateStruct date: 2035-12, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: GCS Ramsay Santé pour l'Enseignement et la Recherche, class: OTHER, descriptionModule briefSummary: The purpose of this study is to identify, at 5 years, the clinical and therapeutic factors associated with improvement in shoulder functionality and quality of life in patients with transfixing (total) rotator cuff injuries undergoing treatment., conditionsModule conditions: Rotator Cuff Injuries, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 519, type: ESTIMATED, armsInterventionsModule interventions name: total transfixing injury to the rotator cuff, outcomesModule primaryOutcomes measure: Shoulder Pain and Disability Index, primaryOutcomes measure: European quality of life scale - EQ5D, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Clinique Maussins-Nollet, city: Paris, zip: 75019, country: France, contacts name: Geoffroy NOURISSAT, MD, role: CONTACT, email: gnourissat@wanadoo.fr, geoPoint lat: 48.85341, lon: 2.3488, hasResults: False
protocolSection identificationModule nctId: NCT06371846, orgStudyIdInfo id: 2023 /10850/I, briefTitle: Comparative Study of the Surface Electrocardiogram Signals During the Implantation of Conduction System Pacing Devices, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-03-14, primaryCompletionDateStruct date: 2024-06-30, completionDateStruct date: 2024-07-30, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Parc de Salut Mar, class: OTHER, descriptionModule briefSummary: Introduction and objectives: Left bundle branch area pacing (LBBAP), is a novel modality of physiologic pacing that requires an adequate assessment of the endocardium as well as the body-surface electrocardiographic signals for a successful pacing-lead implantation. The objective of the study consist of assessing if LBBAP criteria, specifically septal and left bundle branch pacing (LBBP) criteria, can be satisfactory measured using the signals resulting from different cardiac pacing analyzers (PSAs) by comparing them to the 'conventional' signals obtained from multichannel polygraph systems (MPSs) during the implantation procedure.Methods: Comparative observational, prospective, multicenter study between the signals obtained by PSA vs MPS of consecutive patients who underwent a LBBAP strategy as first intention., conditionsModule conditions: Conduction Disorder, conditions: Pacemaker DDD, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 78, type: ESTIMATED, armsInterventionsModule interventions name: Selected signals from Pacing System Analyzers, outcomesModule primaryOutcomes measure: Similarity of signals between multichannel recording system and Pacing System Analyzers, secondaryOutcomes measure: Security, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 99 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Jesus Jiménez López, status: RECRUITING, city: Barcelona, state: Cataluña, zip: 08005, country: Spain, contacts name: Jesus Jiménez López, role: CONTACT, phone: 680714927, email: jejilo78@gmail.com, geoPoint lat: 41.38879, lon: 2.15899, hasResults: False
protocolSection identificationModule nctId: NCT06371833, orgStudyIdInfo id: S-52, briefTitle: PRIMA EU Retrospective & Prospective, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2026-12, completionDateStruct date: 2026-12, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Limacorporate S.p.a, class: INDUSTRY, collaborators name: Iqvia Pty Ltd, descriptionModule briefSummary: This clinical study aims at evaluating clinical, radiographic and patient-reported outcomes after total anatomic or reverse shoulder replacement using PRIMA humeral stem up to 24 months after surgery, in order to assess the short-term performance of the implant. Furthermore, the objective is also to collect short-term data on the survivorship of the implant and the incidence of complications., conditionsModule conditions: Arthroplasty, conditions: Replacement, conditions: Shoulder, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: OTHER, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Shoulder Arthroplasy with PRIMA humeral stem, outcomesModule primaryOutcomes measure: Changes of Costant Murley Score (CS), secondaryOutcomes measure: Changes in the American Shoudler and Elbow Surgeons (ASES) score, secondaryOutcomes measure: Changes in Range of Motion measures, secondaryOutcomes measure: Radiographic stability of the humeral component, secondaryOutcomes measure: Survival rate (Kaplan-Meier estimate), secondaryOutcomes measure: Incidence, type and severity of Adverse Events and Adverse Device Effects, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False