hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06307002, orgStudyIdInfo id: CAS_EB_2024, briefTitle: Evaluating What's My Method? in Barbados, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-11, primaryCompletionDateStruct date: 2024-06-15, completionDateStruct date: 2024-07-30, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: Quinnipiac University, class: OTHER, collaborators name: Barbados Family Planning Association, descriptionModule briefSummary: The purpose of this study is to measure the impact of the What's My Method game on participants' sense of agency, education, and empowerment around contraceptive decision-making. Patients receiving standard of care contraceptive counseling will be compared to those who play the game in addition to counseling., conditionsModule conditions: Contraception Behavior, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: This is a 2 arm randomized controlled trial comparing standard of care (SOC) counseling alone to What's My Method? (WMM) gameplay in addition to SOC., primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: NONE, enrollmentInfo count: 70, type: ESTIMATED, armsInterventionsModule interventions name: Playing a contraception education videogame, outcomesModule primaryOutcomes measure: Contraceptive Self-Efficacy (CSE) score, secondaryOutcomes measure: Method Adoption, secondaryOutcomes measure: Qualitative feedback on game intervention, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 48 Years, stdAges: ADULT, contactsLocationsModule locations facility: Barbados Family Planning Association, status: RECRUITING, city: Bridgetown, state: Saint Michaels, zip: BB11085, country: Barbados, contacts name: Anderson Langdon, MA, role: CONTACT, phone: 2462336750, email: anderson@bfpaonline.com, contacts name: Tiffany Jordan, MD, role: CONTACT, phone: 2468324827, email: tiffany@bfpaonline.com, contacts name: Tiffany Jordan, MD, role: SUB_INVESTIGATOR, geoPoint lat: 13.10731, lon: -59.62021, hasResults: False
protocolSection identificationModule nctId: NCT06306989, orgStudyIdInfo id: Zhengzhou University, briefTitle: Observational Clinical Study of Letermovir for Preventing CMV Infection After Allo-HSCT, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-01-01, primaryCompletionDateStruct date: 2024-09-01, completionDateStruct date: 2025-12-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Cao Weijie, class: OTHER, descriptionModule briefSummary: The goal of this observational study is to get a series of clinical data related to the prevention of CMV infection after allo-HSCT with letemovir. The main question it aims to answer are:* Efficacy and safety of letemovir for the prevention of CMV infection after allo-HSCT.* Optimal initiation of letemovir to prevent CMV infection. Participants will be categorized into high-risk and intermediate-risk groups based on risk factors for CMV infection.Initiate letemovir prophylaxis on day +1 in high-risk patients and on days +7 to +14 in non-high-risk patients.(240 mg, qd in patients with concomitant cyclosporine; 480 mg, qd in patients with concomitant tacrolimus) to +100 days. For patients with comorbid GVHD who require intensive immunosuppression, consider extending the regimen to +200 days.Treatments they will be given and use bullets., conditionsModule conditions: Letemovir for the Prevention of CMV Infection After Allo-HSCT, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 150, type: ESTIMATED, armsInterventionsModule interventions name: Letermovir, outcomesModule primaryOutcomes measure: Prevalence of CMV viremia and CMV disease within 100 days after allogeneic hematopoietic stem cell transplantation., secondaryOutcomes measure: +30-day CMV viremia, CMV disease; +30-day overall survival, non-relapse mortality; +30-day relapse rate; +30-day aGVHD incidence., secondaryOutcomes measure: +100-day overall survival, non-relapse mortality; + 100-day relapse rate; + 100-day aGVHD incidence., secondaryOutcomes measure: +180-day CMV viremia, CMV disease; +30-day overall survival, non-relapse mortality; +180-day relapse rate; +180-day aGVHD incidence., eligibilityModule sex: ALL, minimumAge: 14 Years, maximumAge: 100 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Cao, Weijie, status: RECRUITING, city: Zhengzhou, state: Henan, zip: 450000, country: China, contacts name: Weijie W Cao, doctor of medicine, role: CONTACT, phone: +8618937390269, email: 2549509184@qq.com, contacts name: Mengyang M Zhu, Postgraduate medical students, role: CONTACT, phone: +8615093360671, phoneExt: 0371-66913114, email: Caoweijie2003@126.com, geoPoint lat: 34.75778, lon: 113.64861, hasResults: False
protocolSection identificationModule nctId: NCT06306963, orgStudyIdInfo id: 23-004669, briefTitle: Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias, acronym: GAVE, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-22, primaryCompletionDateStruct date: 2026-03-01, completionDateStruct date: 2026-09-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-04-26, sponsorCollaboratorsModule leadSponsor name: Mayo Clinic, class: OTHER, descriptionModule briefSummary: The researchers are trying to find out more about Gastric Antral Vascular Ectasia (GAVE). This is a condition that affects the blood vessels in the stomach, leading to their enlargement and possible bleeding. It can also cause symptoms such as abdominal pain and nausea. By participating in this study, you will help us learn how often these symptoms occur and how they relate to stomach functioning., conditionsModule conditions: Gastric Antral Vascular Ectasia, conditions: Cirrhosis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Gastric Emptying, outcomesModule primaryOutcomes measure: Abridged Bowel Disease Questionnaire, primaryOutcomes measure: Nepean Dyspepsia Index, primaryOutcomes measure: Leuven Postprandial Distress Scale, secondaryOutcomes measure: Gastric Emptying Half Time (T 1/2) of Solids, secondaryOutcomes measure: Gastric Emptying Half Time (T 1/2) of liquids, eligibilityModule sex: ALL, minimumAge: 19 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Mayo Clinic, status: RECRUITING, city: Rochester, state: Minnesota, zip: 55905, country: United States, contacts name: Taylor N Hines, role: CONTACT, phone: 507-538-9959, email: hines.taylor@mayo.edu, contacts name: Anjali Rajagopal, MBBS, role: CONTACT, phone: 507-266-8779, email: Rajagopal.Anjali@mayo.edu, contacts name: Xiao Jing Wang, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 44.02163, lon: -92.4699, hasResults: False
protocolSection identificationModule nctId: NCT06306950, orgStudyIdInfo id: PMK-00098, briefTitle: Prioritization of Cerebral Deoxygenation in Severe Traumatic Brain Injury and Mortality Benefit., statusModule overallStatus: COMPLETED, startDateStruct date: 2021-04-01, primaryCompletionDateStruct date: 2024-02-28, completionDateStruct date: 2024-02-28, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: Phramongkutklao College of Medicine and Hospital, class: OTHER, descriptionModule briefSummary: Severe traumatic brain injury with a decrease in cerebral oximetry is associated with multiple impaired systemic microcirculations, more morbidities, and a higher mortality rate. When using the brain as an index organ, interventions to improve brain oxygen delivery may have systemic benefits for these patients., conditionsModule conditions: Cerebral Hypoxia, conditions: Severe Traumatic Brain Injury, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: In a prospective study, 80 patients were randomized to either application of near-infrared reflectance spectroscopy (NIRS) monitoring with active display or attempt to make an intervention to keep regional cortical cerebral oxygen saturation (rSO2) ≥ 55% by increased cardiac output, mean arterial pressure, and adjusting the ventilator to hypoventilation (PaCO2 40-45 mmHg) (exclude in radiographic brain herniation) (intervention, n = 40), compared with usual care (n = 40). Clinical outcomes were assessed by a blind observer. Data collection comprised of patients' demographic data, intervention process, and outcomes of treatment assessed by modified Rankin scale (mRS) followed up at 1 year., primaryPurpose: PREVENTION, maskingInfo masking: TRIPLE, maskingDescription: Upon arrival in the emergency department, the randomization envelope was opened, and patients were assigned into either active treatment (intervention) or usual care (control) groups with cerebral oximetry monitoring using NIRS bilaterally (Root; Prime Medical Corporation, MASIMO, USA)., whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, enrollmentInfo count: 80, type: ACTUAL, armsInterventionsModule interventions name: Near infrared spectroscopy neuromonitor to prevent cerebral desaturation, outcomesModule primaryOutcomes measure: modified Rankin scale (mRS) followed up at 1 year, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Phramongkutklao College of Medicine and Hospital, city: Bangkok, zip: 10400, country: Thailand, geoPoint lat: 13.75398, lon: 100.50144, hasResults: False
protocolSection identificationModule nctId: NCT06306937, orgStudyIdInfo id: A24020822, briefTitle: Serum Levels of Vitamin D and IL8 in Patients With Periodontitis, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-09-01, primaryCompletionDateStruct date: 2023-09-30, completionDateStruct date: 2023-09-30, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Mansoura University, class: OTHER, descriptionModule briefSummary: We evaluated vitamin D and IL8 levels in the serum of patients with periodontitis as well as the healthy controls to correlate their levels with the degree of periodontitis., conditionsModule conditions: Periodontal Diseases, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 98, type: ACTUAL, armsInterventionsModule interventions name: Evalution of serum levels of vitamin D and IL8, outcomesModule primaryOutcomes measure: Serum Levels of 25(OH)vitamin D, primaryOutcomes measure: Serum Levels of IL8, secondaryOutcomes measure: Plaque Index (Pl), secondaryOutcomes measure: Clinical Attachment Loss (CAL), secondaryOutcomes measure: Probing Pocket Depth (PPD), eligibilityModule sex: ALL, minimumAge: 21 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule locations facility: Mansoura University, Faculty of Dentistry, city: Mansoura, state: Dakahlia, zip: 35516, country: Egypt, geoPoint lat: 31.03637, lon: 31.38069, hasResults: False
protocolSection identificationModule nctId: NCT06306924, orgStudyIdInfo id: LCCC2303, briefTitle: UNC Metastatic Cancer Radiation Therapy Registry, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-21, primaryCompletionDateStruct date: 2033-05, completionDateStruct date: 2033-05, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-04-26, sponsorCollaboratorsModule leadSponsor name: UNC Lineberger Comprehensive Cancer Center, class: OTHER, descriptionModule briefSummary: The purpose of this registry is to collect clinical data from participants attending UNC Hospitals who present with metastatic cancer and are evaluated to receive radiation therapy as part of their standard of care treatment. The goal of this study is to provide a foundation for studies designed to identify projects across the translational continuum related to metastatic cancer and radiation therapy treatment. The relevant clinical data will be linked to patient-reported outcomes (PROs) thus allowing for a unique and robust dataset. Ultimately, this registry will provide current and future studies with the ability to analyze the correlation of radiation therapy regimens with metastatic cancer outcomes., conditionsModule conditions: Cancer, conditions: Metastatic Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 2000, type: ESTIMATED, armsInterventionsModule interventions name: Radiation therapy, outcomesModule primaryOutcomes measure: Clinical Data, secondaryOutcomes measure: Patient reported outcomes (PRO), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, status: RECRUITING, city: Chapel Hill, state: North Carolina, zip: 27599, country: United States, contacts name: Shivani Sud, MS, role: CONTACT, phone: 919-918-5924, email: sshivani.sud@unchealth.unc.edu, contacts name: Shivani Sud, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 35.9132, lon: -79.05584, hasResults: False
protocolSection identificationModule nctId: NCT06306911, orgStudyIdInfo id: BB-BAM, briefTitle: Bioavailability of Aronia Melanocarpa, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2024-07, completionDateStruct date: 2024-07, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Maastricht University Medical Center, class: OTHER, collaborators name: BioActor, descriptionModule briefSummary: The main objective of this study is to study the bioavailability and kinetics of acute Aronia Melanocarpa supplementation in healthy young (18-35 years) and older adults (55-75 years) adults. During the test day, participants will ingest a drink consisting of Aronia Melanocarpa extract (AME). The bioavailability and kinetics of AME will be assessed via frequent blood sampling, urine collection, and faecal sampling, in which AME and metabolite profiles will be quantified., conditionsModule conditions: Bioavailability, conditions: Kinetics, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 16, type: ESTIMATED, armsInterventionsModule interventions name: Aronia Melanocarpa extract, outcomesModule primaryOutcomes measure: Aronia metabolites in blood, primaryOutcomes measure: Aronia metabolites in urine, secondaryOutcomes measure: Aronia metabolites in feces, secondaryOutcomes measure: length - baseline characteristics, secondaryOutcomes measure: weight - baseline characteristics, secondaryOutcomes measure: blood pressure (systolic and diastolic) - baseline characteristics, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Maastricht University, status: RECRUITING, city: Maastricht, country: Netherlands, contacts name: Sanne Ahles, Msc, role: CONTACT, email: s.ahles@maastrichtuniversity.nl, contacts name: Jogchum Plat, Prof, role: CONTACT, geoPoint lat: 50.84833, lon: 5.68889, hasResults: False
protocolSection identificationModule nctId: NCT06306898, orgStudyIdInfo id: IAV-2024-01, briefTitle: Intra-Arrest-Ventilation in Human Cadavers, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-18, primaryCompletionDateStruct date: 2024-10-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Gerrit Jansen, class: OTHER, collaborators name: Ruhr University of Bochum, collaborators name: Bielefeld University, descriptionModule briefSummary: The study investigates the influence of non-synchronized bag-device-ventilation and intermittent positive pressure ventilation (IPPV), as recommended in the current resuscitation guidelines of the European Resuscitation Concil (tidal Volume (Vt) = 5-6 mL/kg body weight, respiratory rate = 10 min-1) and Chest Compression Synchronized Ventilation (pInsp = 40 mbar; respiratory rate = chest compression rate) with regard to achieving a sufficient tidal volume and the tightness of various supraglottic airway devices (laryngeal mask, i-Gel-laryngeal mask, laryngeal tube) and endotracheal intubation., conditionsModule conditions: Cardiac Arrest, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: Randomized crossover design, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 10, type: ESTIMATED, armsInterventionsModule interventions name: Endotracheal Intubation, interventions name: Laryngeal tube, interventions name: Laryngeal mask, interventions name: I-Gel-Laryngeal Mask, outcomesModule primaryOutcomes measure: Expiratory Volume with different Airway Devices in IPPV, primaryOutcomes measure: Ventilation Pressure with different Airway devices in CCSV, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 100 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06306885, orgStudyIdInfo id: CLF23/03, briefTitle: Effects of Early Sleep After Action Observation and Motor Imagery After Metacarpal Fracture Surgery, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-09-01, completionDateStruct date: 2025-05-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Istituto Clinico Humanitas, class: OTHER, descriptionModule briefSummary: The study aimed to investigate the effects of early sleep after action observation and motor imagery (AOMI) training sessions on manual dexterity in patients with hand immobilization after surgical fixation for metacarpals and phalanges fractures.Fifty-one patients with hand immobilization for surgical fixation of IV or V metacarpals or first phalanges fractures will be randomized into AOMI-sleep (n=17), AOMI-control (n=17), and Control (n=17) group. AOMI-sleep and AOMI-control groups will perform an AOMI-training before sleeping or in the morning respectively, while Control group will be asked to observe landscape video-clips. Participants will be assessed for manual dexterity, hand range of motion, hand disability and quality of life at baseline before and after the training and at 1 month after the training end., conditionsModule conditions: Hand Injuries, conditions: Action Observation, conditions: Motor Imagery, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 51, type: ESTIMATED, armsInterventionsModule interventions name: Action observation plus motor imagery followed by sleep, interventions name: Action observation plus motor imagery, interventions name: Control, outcomesModule primaryOutcomes measure: Changes in Purdue Pegboard Test, secondaryOutcomes measure: Changes in kinematic indexes during Nine Hole Peg Test, secondaryOutcomes measure: Changes in Visual Analogue Scale, secondaryOutcomes measure: Changes in Quick-DASH, secondaryOutcomes measure: Changes in EQ5D, secondaryOutcomes measure: Changes in Total Active Motion, secondaryOutcomes measure: Hand-grip strength, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06306872, orgStudyIdInfo id: ABSK-011-102, briefTitle: A Clinical Trial to Evaluate the Relative Bioavailability of New and Old ABSK-011 Capsules, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-23, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Abbisko Therapeutics Co, Ltd, class: INDUSTRY, descriptionModule briefSummary: The main objective of which is to evaluate the relative bioavailability and PK characteristics of new and old ABSK-011 capsules in a single oral dose, conditionsModule conditions: Healthy Subjects, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: Participants will be randomly assigned 1:1 to arms A (Sequence A) or arms B (Sequence B) to receive a single dose of ABSK-011 orally in two separate doses, spaced at least 4 days apart. Among them, subjects in sequence A will be given ABSK-011 220 mg (100 mg capsule \*2 and 20 mg capsule \*1) and ABSK-011 200 mg (100 mg capsule \*2) on an empty stomach in the morning of the first day of cycle 1 (C1D1) and the first day of cycle 2 (C2D1), respectively. Subjects in sequence B will be given ABSK-011 new formulation 200 mg (100 mg capsule \*2) and ABSK-011 old formulation 220 mg (100 mg capsule \*2 and 20 mg capsule \*1) on an empty stomach in the morning of Cycle 1 day (C1D1) and cycle 2 day (C2D1), respectively., primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 73, type: ESTIMATED, armsInterventionsModule interventions name: Sequence A ABSK-011, interventions name: Sequence B ABSK-011, outcomesModule primaryOutcomes measure: Cmax, primaryOutcomes measure: AUC, primaryOutcomes measure: tmax, secondaryOutcomes measure: AEs, secondaryOutcomes measure: SAEs SAEs, secondaryOutcomes measure: t1/2, secondaryOutcomes measure: Vz/F, secondaryOutcomes measure: CL/F CL/F, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule locations facility: Affiliated Hospital of Jiangnan University, status: RECRUITING, city: Wuxi, state: Jiangsu, zip: 214062, country: China, contacts name: Yiqing Zhao, role: CONTACT, phone: 13358100007, email: 13358100007@126.com, geoPoint lat: 31.56887, lon: 120.28857, hasResults: False