hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06306859, orgStudyIdInfo id: SIKIDI 2024, briefTitle: Development of Health Monitoring System on Patient's Well Being in Dialysis Context, acronym: SIKIDI, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-15, primaryCompletionDateStruct date: 2024-10-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Universitas Muhammadiyah Yogyakarta, class: OTHER, collaborators name: Ministry of Education Culture, Research and Technology, descriptionModule briefSummary: One of the goals in the Sustainable Development Goals (SDGs) is the availability of a healthy and prosperous life for all ages. This goal mentions health priorities i.e. non-communicable diseases. Chronic kidney failure (CRF) is one of the non-communicable diseases that is the main cause of death and disability both in the world and in Indonesia. The prevalence of CRF in Indonesia is 0.5% with 83.2% of patients being of productive age and the highest number of CRF patients in North Kalimantan, Southeast Sulawesi, DKI Jakarta and Yogyakarta. Monitoring and evaluation of patients with CRF is currently mostly carried out conventionally not using health technology that is integrated with hospital information systems. This study aims to design and provide a health information system for patients with CRF, hereinafter referred to as SIKIDI, which integrates mobile-health applications used independently by patients with existing information systems in hospitals., conditionsModule conditions: Quality of Life, conditions: Self Efficacy, conditions: Chronic Kidney Diseases, conditions: M-health, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The intervention group will be given access to m-health to monitor and education provision for about four weeks, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: The sample will be divided based on the schedule of hemodialysis. Intervention group will be chosen from Monday-Thursday., whoMasked: PARTICIPANT, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Using m-health for monitoring and education provision, interventions name: Standard care, outcomesModule primaryOutcomes measure: Quality of Life that will be measured using KDQOL before and after intervention, secondaryOutcomes measure: Self-efficacy that will be measured using CKD SE before and after, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: RS PKU Muhammadiyah Bantul, city: Bantul, state: Yogy, zip: 55183, country: Indonesia, contacts name: Indra Prasetyantori, Master, role: CONTACT, geoPoint lat: -7.88806, lon: 110.32889, hasResults: False
protocolSection identificationModule nctId: NCT06306846, orgStudyIdInfo id: 11235794, briefTitle: Neoadjuvant SBRT in Localized Advanced HNSCC, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-10-01, primaryCompletionDateStruct date: 2026-12-31, completionDateStruct date: 2026-12-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Jiang Feng, class: OTHER, descriptionModule briefSummary: The response rate of HNSCC to immune checkpoint blockade was not satisfied. Improving the mPR rate of neoadjuvant immunotherapy through the combination with other treatment methods is an important way to further improve the prognosis of such patients. This study aims to explore the efficacy and safety of PD-1 monoclonal antibody with neoadjvant SBRT and chemotherapy. The triple mode not only can Increase the effectiveness of neoadjuvant therapy，meanwhile，the in situ tumor vaccine inoculation effect generated by enhancing the release of specific antigens after tumor radiotherapy with PD-1 monoclonal antibody achieves a sustained anti-tumor immune effect throughout the body， reducing postoperative adjuvant radiotherapy and chemotherapy. The triple mode has important exploratory value in achieving high quality and long-term survival for patients, and may provides a more efficient mode for locally advanced HNSCC., conditionsModule conditions: Head and Neck Squamous Carcinoma, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 81, type: ESTIMATED, armsInterventionsModule interventions name: SBRT+immunochemotherpy, interventions name: Immunochemotherapy, interventions name: cetuximab+immunochemotharpy, outcomesModule primaryOutcomes measure: major pathology response (MPR), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Zhejiang Cancer Hospital, status: RECRUITING, city: Hangzhou, state: Zhejiang, zip: 310022, country: China, contacts name: Feng Jiang, MD, role: CONTACT, phone: 0086-571-88128202, email: jiangfeng@zjcc.org.cn, geoPoint lat: 30.29365, lon: 120.16142, hasResults: False
protocolSection identificationModule nctId: NCT06306833, orgStudyIdInfo id: CLBP-sEMG-14022024, briefTitle: The Surface EMG Biofeedback as an Alternative Therapy to Reduce Chronic Low Back Pain, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-10-01, primaryCompletionDateStruct date: 2024-05, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Amaila Fazal [afazal], class: OTHER, collaborators name: University of Karachi, descriptionModule briefSummary: The prevalence of chronic low back pain (CLBP) among the Pakistani population is reported to be as high as 78% leading towards different physiological and psychosocial alterations with the worst cases suffering from disabilities. CLBP is a multifactorial phenomenon in which age, gender, comorbidities, lifestyle conditions, profession, working hours, and different stressors play their roles in its causation. However, different therapeutic techniques have been determined to reduce CLBP. Thus, this study aimed to assess the effectiveness of the biofeedback surface EMG (sEMG) technique in reducing chronic low back pain among sufferers in the long run., conditionsModule conditions: Chronic Low Back Pain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: Surface Electromyography (sEMG) Biofeedback, outcomesModule primaryOutcomes measure: Pain Intensity and interference, primaryOutcomes measure: Lower back pain related Disability, primaryOutcomes measure: Quality of Life with chronic low back pain, primaryOutcomes measure: Pain and Disability-related Anxiety, secondaryOutcomes measure: Substance P, secondaryOutcomes measure: Cortisol, secondaryOutcomes measure: Beta Endorphins, eligibilityModule sex: ALL, minimumAge: 25 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Psychophysiology Lab, University of Karachi, status: RECRUITING, city: Karachi, state: Sindh, zip: 75270, country: Pakistan, contacts name: Shamoon Naushad, PhD, role: CONTACT, phone: 03333549258, geoPoint lat: 24.8608, lon: 67.0104, hasResults: False
protocolSection identificationModule nctId: NCT06306820, orgStudyIdInfo id: 36264MS257/7/2023, briefTitle: Ultrasound Guided Recruitment Manauvere Versus Individualized Positive End Expiratory Pressure in Pediatric Patients Undergoing Laparoscopic Abdominal Surgery, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-12, primaryCompletionDateStruct date: 2024-08-01, completionDateStruct date: 2024-08-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-13, sponsorCollaboratorsModule leadSponsor name: Tanta University, class: OTHER, descriptionModule briefSummary: The aim of this prospective randomized controlled study is to compare the effect of US-guided Recruitment Manauvere (RM) versus individualized positive end-expiratory pressure (PEEP) on oxygenation and preventing respiratory complications in pediatric patients undergoing laparoscopic abdominal surgeries., conditionsModule conditions: Ultrasound Guided Recruitment Manauvere, conditions: End Expiratory Pressure, conditions: Pediatric Patients, conditions: Laparoscopic Abdominal Surgery, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: Fixed PEEP, interventions name: Ultrasound-guided lung recruitment, interventions name: Individualized PEEP, outcomesModule primaryOutcomes measure: Intraoperative oxygenation, secondaryOutcomes measure: Lung ultrasound scores, secondaryOutcomes measure: Mean arterial blood pressure (MAP), secondaryOutcomes measure: Heart rate, secondaryOutcomes measure: Postoperative pulmonary complication, eligibilityModule sex: ALL, minimumAge: 3 Years, maximumAge: 8 Years, stdAges: CHILD, contactsLocationsModule locations facility: Tanta University, status: RECRUITING, city: Tanta, state: El-Gharbia, zip: 31527, country: Egypt, contacts name: Reham M Rezk, MBBCH, role: CONTACT, phone: 00201013193723, email: rehamrezk95@gmail.com, contacts name: Soher M Soliman, MD, role: SUB_INVESTIGATOR, contacts name: Shaimaa F Abdelkader, MD, role: SUB_INVESTIGATOR, contacts name: Shaimaa E Shaban, MD, role: SUB_INVESTIGATOR, geoPoint lat: 30.78847, lon: 31.00192, hasResults: False
protocolSection identificationModule nctId: NCT06306781, orgStudyIdInfo id: HI-IM-002, briefTitle: A Clinical Trial Evaluating the Safety, Tolerability, and Preliminary Efficacy of HCL001 Cell Injection (Homologous Allogeneic Hepatocytes) in Patients With Decompensated Cirrhosis, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-30, primaryCompletionDateStruct date: 2026-07-30, completionDateStruct date: 2026-12-30, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: RenJi Hospital, class: OTHER, descriptionModule briefSummary: This study protocol is designed to evaluate the clinical efficacy, safety, and tolerability of HCL001 cell injection in the treatment of decompensated cirrhosis. The aim is to provide stronger evidence for the clinical application of HCL001 cell injection in the treatment of decompensated cirrhosis, thereby attempting to improve patients' survival and quality of life to meet the clinical needs for treating decompensated liver cirrhosis., conditionsModule conditions: Decompensated Cirrhosis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 18, type: ESTIMATED, armsInterventionsModule interventions name: HCL001 cell (homologous allogeneic hepatocytes) injection, outcomesModule primaryOutcomes measure: Types and incidence of treatment-related adverse events., primaryOutcomes measure: Dose-Limiting Toxicity (DLT), primaryOutcomes measure: Maximum Tolerated Dose (MTD), secondaryOutcomes measure: Child-Pugh grading., secondaryOutcomes measure: Number of participants with abnormal laboratory tests results, secondaryOutcomes measure: The percentage of participants with improved liver conditions (including changes in portal vein diam, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06306768, orgStudyIdInfo id: STU00219979, briefTitle: Remote Therapeutic Monitoring Exercise Tracking, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2028-03, completionDateStruct date: 2028-03, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Shirley Ryan AbilityLab, class: OTHER, descriptionModule briefSummary: The purpose of this study is to examine physical activity and exercise behaviors in people with Parkinson's Disease and Multiple Sclerosis over the course of 1-year using a cloud-based remote monitoring platform., conditionsModule conditions: Parkinson Disease, conditions: Multiple Sclerosis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: Activity Monitoring, outcomesModule primaryOutcomes measure: Physical Activity Metric 1, primaryOutcomes measure: Physical Activity Metric 2, secondaryOutcomes measure: Exercise Self Efficacy, secondaryOutcomes measure: Quality of Life from PROMIS 10-b, secondaryOutcomes measure: Quality of Life from PROMIS-29, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 89 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Shirley Ryan AbilityLab, status: RECRUITING, city: Chicago, state: Illinois, zip: 60611, country: United States, contacts name: Hannah Redd, DPT, role: CONTACT, email: hredd@sralab.org, contacts name: Kristen Hohl, DPT, role: CONTACT, email: khohl@sralab.org, geoPoint lat: 41.85003, lon: -87.65005, hasResults: False
protocolSection identificationModule nctId: NCT06306742, orgStudyIdInfo id: ct9874, briefTitle: Open-label Placebo in Manual Therapy, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-26, primaryCompletionDateStruct date: 2025-12, completionDateStruct date: 2026-06, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Studio Osteopatico Busto Arsizio, class: OTHER, descriptionModule briefSummary: to investigate the effects of placebo in patients affected by low-back pain., conditionsModule conditions: Low Back Pain, Recurrent, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Open-label placebo, interventions name: Osteopathic manipulative treatment, outcomesModule primaryOutcomes measure: Change in Numeric Rating Scale, primaryOutcomes measure: Adverse effects, secondaryOutcomes measure: Change in measures of Von Frey filaments, secondaryOutcomes measure: Changes in algometer measurements, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: CTFO, status: RECRUITING, city: Saronno, state: Varese, zip: 21047, country: Italy, contacts name: CFTO, role: CONTACT, phone: +39 02 96701013, email: cfto@aimoedu.it, geoPoint lat: 45.62513, lon: 9.03517, hasResults: False
protocolSection identificationModule nctId: NCT06306729, orgStudyIdInfo id: 316308, briefTitle: Computational Assessment of Bioprosthetic Aortic Valve Function, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-04-01, completionDateStruct date: 2026-04-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Royal Brompton & Harefield NHS Foundation Trust, class: OTHER, collaborators name: Edwards Lifesciences, collaborators name: Imperial College London, descriptionModule briefSummary: Bioprosthetic valves are usually made of biological tissue that are mounted to a frame and are designed to function similarly to a healthy natural valve. Edwards Magna Ease and Intuity Elite bioprosthetic valves have similar leaflets and mounting designs. However, the valves are implanted in the patient in different ways (one is stitched to the wall of the left ventricular outflow tract, and the other is held in place by the radial force of the valve skirt). The study aims to understand in more detail how the different valves interact with the left ventricular outflow tract and aortic root., conditionsModule conditions: CFD, conditions: Valve Heart Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: Computed Tomography, Magnetic Resonance Imaging, outcomesModule primaryOutcomes measure: blood flow velocities, primaryOutcomes measure: Time average wall shear stress (TAWSS), secondaryOutcomes measure: Patient's satisfaction, secondaryOutcomes measure: Evidence of major adverse cardiac and cerebrovascular events (MACCE), secondaryOutcomes measure: Mortality, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06306716, orgStudyIdInfo id: LEO.2021.10, briefTitle: Single Center Clinical Study on New Negative Pressure Wound Therapy Dressing in the Management of Chronic & Acute Wounds, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-10, primaryCompletionDateStruct date: 2025-04-30, completionDateStruct date: 2025-04-30, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Smith & Nephew, Inc., class: INDUSTRY, descriptionModule briefSummary: The purpose of the study is to evaluate the clinical performance of a new Negative Pressure Wound Therapy dressing in the management of chronic and acute wounds., conditionsModule conditions: Chronic Wounds, conditions: Acute Wounds, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 23, type: ESTIMATED, armsInterventionsModule interventions name: RENASYS Film with AIRLOCK Technology, outcomesModule primaryOutcomes measure: Wound Healing Status, secondaryOutcomes measure: Percentage Reduction in Wound Volume from Baseline to Week 3, secondaryOutcomes measure: Percentage Reduction in Wound Area from Baseline to Week 3, secondaryOutcomes measure: Percentage Reduction in Wound depth from Baseline to Week 3, secondaryOutcomes measure: Percentage Area of Wound Bed Covered with Granulation Tissue, secondaryOutcomes measure: Peri-wound Pain Scores at Dressing Removal, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Lawson Health Research Institute, city: London, state: Ontario, zip: N6C 2R5, country: Canada, contacts name: Teresa Novic, role: CONTACT, email: teresa.novick@lhsc.on.ca, contacts name: Adam Power, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 42.98339, lon: -81.23304, hasResults: False
protocolSection identificationModule nctId: NCT06306690, orgStudyIdInfo id: 6401, briefTitle: Biomarkers in Retinitis Pigmentosa, acronym: RPMARKER, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-01, primaryCompletionDateStruct date: 2025-04, completionDateStruct date: 2025-04, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, class: OTHER, descriptionModule briefSummary: The objective of this study is to discover biomarkers that demonstrate a correlation between the severity of retinitis pigmentosa (RP) and the thickness of the retinal pigment epithelium (RPE). These biomarkers will serve as prognostic indicators for various kinds of retinitis pigmentosa. The objective of this study is to find biomarkers that establish a correlation between the severity of retinitis pigmentosa and the thickness of the retinal pigment epithelium (RPE), which can serve as a prognostic indicator for Retinitis Pigmentosa., conditionsModule conditions: Retinitis Pigmentosa, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 35, type: ESTIMATED, armsInterventionsModule interventions name: OCT, OCT angiography, flicker ERG and Ultra Wide Field retinography and autofluorescence., outcomesModule primaryOutcomes measure: Retinal pigment epithelium changes in Retinitis Pigmentosa., secondaryOutcomes measure: Retinitis Pigmentosa biomarkers, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Maria Cristina Savastano, status: RECRUITING, city: Roma, zip: 00198, country: Italy, contacts name: Maria C Savastano, role: CONTACT, phone: 3200609905, email: mariacristina.savastano@gmail.com, geoPoint lat: 41.89193, lon: 12.51133, hasResults: False