protocolSection identificationModule nctId: NCT06271655, orgStudyIdInfo id: BFD-RST-23-004, briefTitle: Rapid Diagnosis of Viral Acute Respiratory Infection to Decrease Unnecessary Antibiotic Utilization in the Emergency Department (RADIATE), acronym: RADIATE, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-12, primaryCompletionDateStruct date: 2024-09-30, completionDateStruct date: 2024-09-30, studyFirstPostDateStruct date: 2024-02-22, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Christopher Payette, class: OTHER, collaborators name: BioMérieux, descriptionModule briefSummary: The study titled " The Effect of Definitive Identification of Viral Etiology in Emergency Department Patients with Acute Respiratory Infection on Antibiotic Utilization (RADIATE)" aims to investigate the effectiveness of a rapid diagnostic approach in reducing unnecessary antibiotic use in the emergency department (ED) for patients presenting with acute respiratory illness (ARI) due to a virus. Using a prospective design, eligible participants are individuals who visit the ED with complaints related to acute respiratory illness. The study will employ a single-arm consecutive enrollment approach. The intervention involves the implementation of a rapid point-of-care multiplex polymerase chain reaction (PCR) test to promptly identify the viral cause of the infection. By utilizing a rapid diagnostic tool to identify viral etiology, the study aims to provide healthcare professionals in the ED with more accurate information to guide treatment decisions. Ultimately, the goal is to decrease the unnecessary use of antibiotics for ARI's due to a virus, which has several negative outcomes including promotion of antibiotic resistance, exacerbating ED length of stay and encouraging unnecessary additional diagnostic tests., conditionsModule conditions: Acute Respiratory Infection, conditions: Viral Infection, conditions: Upper Respiratory Tract Infections, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: SPOTFIRE R Panel, outcomesModule primaryOutcomes measure: Antibiotic Use, secondaryOutcomes measure: Emergency Department Length of Stay, secondaryOutcomes measure: Utilization of Alternative Tests, secondaryOutcomes measure: Patient Confidence in Diagnosis, secondaryOutcomes measure: Provider Confidence in Diagnosis, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: George Washington University Hospital, status: RECRUITING, city: Washington, state: District of Columbia, zip: 20037, country: United States, contacts name: Ryan Heidish, role: CONTACT, email: rheidish@mfa.gwu.edu, contacts name: Christopher Payette, MD, role: CONTACT, email: cpayette@mfa.gwu.edu, contacts name: Christopher Payette, MD, role: PRINCIPAL_INVESTIGATOR, contacts name: Andrew Meltzer, MD, MS, role: SUB_INVESTIGATOR, geoPoint lat: 38.89511, lon: -77.03637, hasResults: False