hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06350565, orgStudyIdInfo id: DEX20240104, briefTitle: A Clinical Pharmacological Study of Dose Halving of Dexamethasone in Pregnant Women With Preterm Labour With Preterm Birth at Greater Than or Equal to 34 Gestational Weeks (34GW+), statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-30, primaryCompletionDateStruct date: 2025-04-30, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Peking University Third Hospital, class: OTHER, descriptionModule briefSummary: This study plans to conduct a DEX dose halving study and a normal dose study in 34+0-35+6 GW women with preterm preterm labour. In addition, this study plans to conduct a DEX dose halving study and a normal dose study in 34-38+6 GW preterm pregnant women with GDM or diabetic co-pregnancy to explore the feasibility of dose halving in pregnant women with diabetes mellitus., conditionsModule conditions: Respiratory Distress Syndrome of Newborn, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 48, type: ESTIMATED, armsInterventionsModule interventions name: Dexamethasone, outcomesModule primaryOutcomes measure: Respiratory distress syndrome, primaryOutcomes measure: PK parameters (analysed in conjunction with population pharmacokinetic (PPK) modelling): area under the blood concentration curve, Cmax, Tmax, Kel, t1/2, CL, VZ, primaryOutcomes measure: Pharmacodynamics, primaryOutcomes measure: Measurability indicators, primaryOutcomes measure: Blood biochemistry findings in newborns, primaryOutcomes measure: DEX potential safety marker test, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06350552, orgStudyIdInfo id: PA224ES-1-03, briefTitle: Prevalence of Postural Abnormalities in Dialysis Patients, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2024-04, completionDateStruct date: 2024-04, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Pardis Specialized Wellness Institute, class: OTHER, descriptionModule briefSummary: The goal of this observational study is to investigate and compare the prevalence of forward head, hyper kyphosis and balance in hemodialysis and peritoneal dialysis patients. The main questions it mains to answer are:What is the prevalence of forward head posture in hemodialysis and peritoneal dialysis patients? What is the prevalence of hyper kyphosis in hemodialysis and peritoneal dialysis patients? Is there any relation between postural abnormalities and physical function in hemodialysis and peritoneal dialysis patients?Participants will answer 2 questionnaires and will do some functional tests., conditionsModule conditions: End Stage Renal Disease, conditions: Hemodialysis Complication, conditions: Peritoneal Dialysis Complication, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 390, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Prevalence of thoracic hyper kyphosis, primaryOutcomes measure: Prevalence of forward head, secondaryOutcomes measure: Balance level, secondaryOutcomes measure: Cardiopulmonary function's level, secondaryOutcomes measure: Fall risk level, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Khorshid Dialysis Center, city: Isfahan, country: Iran, Islamic Republic of, geoPoint lat: 32.65246, lon: 51.67462, hasResults: False
protocolSection identificationModule nctId: NCT06350539, orgStudyIdInfo id: 10-007, briefTitle: Personalized Models for Cancer Research, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-15, primaryCompletionDateStruct date: 2034-02-15, completionDateStruct date: 2034-02-15, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: New York Stem Cell Foundation Research Institute, class: OTHER, collaborators name: Stevens Institute of Technology, descriptionModule briefSummary: The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate cancer research ranging from disease mechanisms to personalized medicine approaches that will help to realize the promise of precision medicine for oncology., conditionsModule conditions: Solid Tumor, Adult, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: OTHER, enrollmentInfo count: 500, type: ESTIMATED, armsInterventionsModule interventions name: Biological Sample Collection, outcomesModule primaryOutcomes measure: Implement organoid culture technologies., primaryOutcomes measure: Validate genotypic and phenotypic relevance of tumor-derived organoids for biobanking., primaryOutcomes measure: Establish functional testing using organoid cultures alone or in combination with additional cell types., primaryOutcomes measure: Perform drug testing and screens to identify new targets and/or new therapeutic strategies to effectively treat cancer., primaryOutcomes measure: Develop a Laboratory Developed Test (LDT) for CLEP/FDA approval that will inform clinicians of each patient's tumor responses to FDA approved drugs., primaryOutcomes measure: Develop stem cells from individual patient samples to study tumor evolution., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: New York Stem Cell Foundation Research Institute, status: RECRUITING, city: New York, state: New York, zip: 10019, country: United States, contacts name: Becca Wood, role: CONTACT, phone: 212-927-1801, email: clinicalresearch@nyscf.org, contacts name: Lisa Voltolina, role: CONTACT, phone: 6462133911, email: lvoltolina@nyscf.org, contacts name: Laura Andres-Martin, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 40.71427, lon: -74.00597, hasResults: False
protocolSection identificationModule nctId: NCT06350526, orgStudyIdInfo id: PULMHEMA, briefTitle: Radiological Characterization of Pulmonary Involvement in Patients With Hematological Diseases, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2025-03-01, completionDateStruct date: 2025-06-01, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: New Valley University, class: OTHER, descriptionModule briefSummary: Hematologic malignancies are heterogeneous groups of neoplasia, with frequent pulmonary complications. These complications may be secondary to the patient's comorbidities, to the hemopathy itself, or its treatments. Divided into infectious and non-infectious complications, the etiologies are numerous and varied. This makes the diagnostic approach complex for the clinicians, conditionsModule conditions: Hematologic Diseases, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: RETROSPECTIVE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: Complete Blood Count, interventions name: C-reactive protein, interventions name: O2 saturation, interventions name: Serum ferritin and D-dimer, interventions name: Liver and renal function tests, interventions name: Lactate dehydrogenase, interventions name: coronavirus (SARS-CoV-2) swab, interventions name: CT chest, outcomesModule primaryOutcomes measure: Number of patients who had certain radiological patterns associated with pulmonary complications in patients diagnosed with various hematological diseases, secondaryOutcomes measure: Number of patients who developed complications, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06350513, orgStudyIdInfo id: NecmettinE, briefTitle: The Effect of Animated Movies and Storybooks on Fear and Anxiety Levels in Children With Type 1 Diabetes, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-25, primaryCompletionDateStruct date: 2024-09-25, completionDateStruct date: 2025-02-25, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Selverhan Yurttutan, class: OTHER, descriptionModule briefSummary: This study aims to evaluate the effects of animated films and story books on the fear and anxiety levels of children with newly diagnosed type 1 diabetes., conditionsModule conditions: Diabetes Mellitus, Type 1, conditions: Child, Only, conditions: Anxiety, conditions: Fear, conditions: Nurse, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Parallel Group (Experiment-Control) Randomized Controlled Experimental, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 64, type: ESTIMATED, armsInterventionsModule interventions name: Animation movie, story book, outcomesModule primaryOutcomes measure: State Anxiety Inventory for Children (STAI-C), primaryOutcomes measure: State Anxiety Inventory for Children (STAI-C), primaryOutcomes measure: State Anxiety Inventory for Children (STAI-C), secondaryOutcomes measure: Children's Fear Scale, secondaryOutcomes measure: Children's Fear Scale, secondaryOutcomes measure: Children's Fear Scale, eligibilityModule sex: ALL, minimumAge: 7 Years, maximumAge: 12 Years, stdAges: CHILD, contactsLocationsModule locations facility: Semra Köse, city: Konya, state: Meram, country: Turkey, geoPoint lat: 37.87135, lon: 32.48464, locations facility: Necmettin Erbakan Üniversity, city: Konya, country: Turkey, geoPoint lat: 37.87135, lon: 32.48464, hasResults: False
protocolSection identificationModule nctId: NCT06350500, orgStudyIdInfo id: I-3858823, briefTitle: A Patient Navigation Program for Addressing Disparities in Breast Cancer Care, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2026-01-01, completionDateStruct date: 2026-01-01, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Roswell Park Cancer Institute, class: OTHER, descriptionModule briefSummary: This clinical trial evaluates a patient navigation program for addressing disparities in breast cancer care. The navigation program is designed to help improve patient knowledge about clinical and supportive care services, navigate to existing services, help manage barriers to care, and enhance patient skills related to management of cancer treatment. Offering a patient navigation program may increase health equity and improve social needs and quality of life over time for newly diagnosed breast cancer patients., conditionsModule conditions: Breast Carcinoma, conditions: Breast Ductal Carcinoma in Situ, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: NONE, enrollmentInfo count: 126, type: ESTIMATED, armsInterventionsModule interventions name: Patient Navigation, interventions name: Questionnaire, outcomesModule primaryOutcomes measure: Enrollment rate, primaryOutcomes measure: Reasons for refusal, primaryOutcomes measure: Retention Rate, primaryOutcomes measure: Reasons for discontinuation, secondaryOutcomes measure: European Organization for Research and Treatment of Cancer Quality of Life Scale (EORTC QLQ-C30), secondaryOutcomes measure: Social Determinates of health, secondaryOutcomes measure: Barriers to care, secondaryOutcomes measure: Use of supportive services, secondaryOutcomes measure: Patient Satisfaction survey, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06350448, orgStudyIdInfo id: WMT-CN-RH, briefTitle: Washed Microbiota Transplantation for Rhinitis, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2029-05-01, completionDateStruct date: 2029-08-01, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: The Second Hospital of Nanjing Medical University, class: OTHER, descriptionModule briefSummary: The common symptoms of rhinitis include nasal itching, sneezing, anterior or posterior nasal leakage, and nasal congestion. Rhinitis can be classified as allergic rhinitis (AR) and non-allergic rhinitis (NAR) based on the presence of a specific allergen. Increasing evidence showed that gut microbiota can influence the development of AR. Although few studies have reported the association between NAR and gut microbiota, we found that washed microbiota transplantation (WMT) could improve nasal symptoms, whether it is AR or NAR. This clinical trial aims to evaluate the efficacy and safety of WMT for rhinitis., conditionsModule conditions: Rhinitis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Washed Microbiota Transplantation, outcomesModule primaryOutcomes measure: Changes in the reflective total nasal symptom score (rTNSS), secondaryOutcomes measure: Changes in the combined symptoms and medication score (CSMS), secondaryOutcomes measure: Changes in the rhinoconjunctivitis quality of life questionnaire (RQLQ) score, secondaryOutcomes measure: Changes in the single reflective nasal symptoms score, secondaryOutcomes measure: Specific IgE, secondaryOutcomes measure: Inflammatory factors, secondaryOutcomes measure: Flow cytometric analysis of lymphocyte clusters, secondaryOutcomes measure: The incidence of treatment-related adverse events (AE) assessed by CTCAE, Version 5.0, eligibilityModule sex: ALL, minimumAge: 6 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University, city: Nanjing, state: Jiangsu, zip: 210011, country: China, contacts name: Faming Zhang, MD,PhD, role: CONTACT, phone: 086-25-58509883, email: fzhang@njmu.edu.cn, geoPoint lat: 32.06167, lon: 118.77778, hasResults: False
protocolSection identificationModule nctId: NCT06350435, orgStudyIdInfo id: CUHK 2023.569, briefTitle: Effects of Prefabricated Foot Orthoses With and Without Metatarsal Pads on Central Metatarsalgia, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-12-18, primaryCompletionDateStruct date: 2024-04-26, completionDateStruct date: 2024-05-31, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Chinese University of Hong Kong, class: OTHER, collaborators name: Pamela Youde Nethersole Eastern Hospital, descriptionModule briefSummary: Compare the effects of prefabricated foot orthoses with and without metatarsal pads on pain intensity in the 2nd to 4th metatarsophalangeal joints, foot and ankle functional abilities as well as the occurrence of plantar callosities among patients with central metatarsalgia., conditionsModule conditions: Metatarsalgia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 32, type: ACTUAL, armsInterventionsModule interventions name: Prefabricated foot orthoses (PFO) with metatarsal pads, interventions name: Prefabricated foot orthoses (PFO) without metatarsal pads, outcomesModule primaryOutcomes measure: Pain intensity at the 2nd to 4th metatarsophalangeal joints during walking in shoes on Visual Analogue Scale, secondaryOutcomes measure: Foot and Ankle Outcome Score, secondaryOutcomes measure: Size of callosities and corns on the plantar area of the 2nd to 4th metatarsophalangeal joints, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Pamela Youde Nethersole Eastern Hospital, city: Hong Kong, country: Hong Kong, geoPoint lat: 22.27832, lon: 114.17469, hasResults: False
protocolSection identificationModule nctId: NCT06350422, orgStudyIdInfo id: Microgravity-ChinaPLAGH, briefTitle: Neuroimage Genome Study of Neuroplasticity Associated With Microgravity, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2022-01-01, primaryCompletionDateStruct date: 2024-10-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Chinese PLA General Hospital, class: OTHER, descriptionModule briefSummary: This clinical trial investigates the neuroplasticity and cognitive status changes of the human brain in microgravity. To explore the relationship between cognitive status changes and brain functional activities, gray matter and white matter changes under microgravity exposure, screen and identify representative image markers, so as to provide decision-making information for the cognitive status changes of relevant personnel under microgravity environment., conditionsModule conditions: Microgravity, conditions: Neuroplasticity, conditions: MRI, conditions: Repeatable Battery for the Assessment of Neuropsychological Status, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 26, type: ACTUAL, armsInterventionsModule interventions name: Head-Down tilt Bed Rest test, outcomesModule primaryOutcomes measure: Local brain functional activity, primaryOutcomes measure: Brain functional connectivity, primaryOutcomes measure: Brain structure - Morphology, primaryOutcomes measure: Brain fiber bundle and brain Diffusion index, primaryOutcomes measure: Brain blood flow, primaryOutcomes measure: Imaging indexes and clinical scale scores, eligibilityModule sex: MALE, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Chinese PLA General Hospital, city: Beijing, country: China, geoPoint lat: 39.9075, lon: 116.39723, hasResults: False
protocolSection identificationModule nctId: NCT06350409, orgStudyIdInfo id: CTN-0146, secondaryIdInfos id: UG1DA015831-22S4, type: NIH, link: https://reporter.nih.gov/quickSearch/UG1DA015831-22S4, briefTitle: Adolescent Outcomes of Post-operative Opioid EXposure, acronym: APEX, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-08-10, primaryCompletionDateStruct date: 2026-09-10, completionDateStruct date: 2026-10-10, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Sharon Levy, class: OTHER, collaborators name: National Institute on Drug Abuse (NIDA), collaborators name: National Institutes of Health (NIH), descriptionModule briefSummary: The goal of this observational study is to examine the factors associated with the transition from medical exposure to opioids with "signposts" of future opioid use disorder among adolescent surgical patients. The main question aims to identify factors (moderators, mediators, and covariates) associated with risk factors for opioid use disorder (ROUD) in the 12 months following major surgery with opioid exposure among adolescents aged 12-17. Participants will be asked to complete electronic surveys pre- and post-operatively and approve the collection of peri-operative data from the Electronic Medical Record to assess correlations., conditionsModule conditions: Opioid Use Disorder, conditions: Pain, Chronic, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 20000, type: ESTIMATED, outcomesModule primaryOutcomes measure: Risk of opioid use disorder due to prolonged pain that develops within the first year after surgery., primaryOutcomes measure: Risk of opioid use disorder due to prolonged opioid use that develops within the first year after surgery., primaryOutcomes measure: Risk of opioid use disorder due to postoperative non-medical use of prescription opioids (NMUPO) that develops within the first year after surgery., primaryOutcomes measure: Risk of opioid use disorder due to increased rate of change in substance use that develops within the first year after surgery., primaryOutcomes measure: Risk of opioid use disorder due to post-surgical trauma that develops within the first year after surgery., eligibilityModule sex: ALL, minimumAge: 12 Years, maximumAge: 17 Years, stdAges: CHILD, contactsLocationsModule locations facility: Boston Childrens Hopsital - Division of Addiction Medicine, city: Boston, state: Massachusetts, zip: 02115, country: United States, contacts name: Melissa Brogna, MSW, role: CONTACT, phone: 857-218-4311, email: Melissa.Brogna@childrens.harvard.edu, geoPoint lat: 42.35843, lon: -71.05977, hasResults: False