hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06338111, orgStudyIdInfo id: 2461, briefTitle: Interventions Meant to Improve the Outcome of Critical Care Patients in the ED, statusModule overallStatus: COMPLETED, startDateStruct date: 2020-11-09, primaryCompletionDateStruct date: 2022-12-06, completionDateStruct date: 2023-04-30, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Iuliu Hatieganu University of Medicine and Pharmacy, class: OTHER, descriptionModule briefSummary: This study aims to identify the prognostic role of procalcitonin (PCT), soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1), the soluble form of the urokinase plasminogen activator receptor (suPAR), highly sensitive C-reactive protein (hs-CRP), Interleukin-6 (IL-6), and azurocidin 1 (AZU1) in 28-day mortality for patients with sepsis in Emergency Department., conditionsModule conditions: Sepsis Syndrome, conditions: Emergency Department, conditions: Biomarker, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 67, type: ACTUAL, armsInterventionsModule interventions name: ELISA Sepsis Biomarkers dosage, outcomesModule primaryOutcomes measure: Can we better predict mortality in septic patients from the Emergency Department?, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 90 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Cluj County Hospital Emergency Department, city: Cluj-Napoca, state: Cluj, zip: 400006, country: Romania, geoPoint lat: 46.76667, lon: 23.6, hasResults: False
protocolSection identificationModule nctId: NCT06338098, orgStudyIdInfo id: HFNVSH.001, briefTitle: Effect of an 8-week Heartfulness Meditation Program on Burnout and Stress at Veterinary Specialty Hospital, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-02-28, primaryCompletionDateStruct date: 2023-10-02, completionDateStruct date: 2023-10-02, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-04-02, sponsorCollaboratorsModule leadSponsor name: Heartfulness Institute, class: OTHER, collaborators name: Angell Animal Medical Center, descriptionModule briefSummary: This quantitative study assesses the effects of meditation and relaxation practices on the reduction of burnout and stress in veterinary care workers. Assessments at baseline will include the Perceived Stress Scale (PSS) and Maslach Burnout Toolkit, and the same questionnaires were collected in Week 8 and Week 16. The Google form questionnaire will ask the participant for their email address. The form will also include a question eliciting interest in participation in the 8-weeks Heartfulness Meditation program. The program will include tools that promote a heart-based nurturing environment focusing on relaxation, and tools to cope with burnout., conditionsModule conditions: Stress, conditions: Burnout, Professional, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 74, type: ACTUAL, armsInterventionsModule interventions name: 8-week wellness and relaxation meditation program, outcomesModule primaryOutcomes measure: Assess the current level of Anxiety, primaryOutcomes measure: Changes level of Stress, primaryOutcomes measure: Assess the current level of Burnout, primaryOutcomes measure: Changes level of Burnout, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Angell Animal Medical Center,, city: Boston, state: Massachusetts, zip: 02130, country: United States, geoPoint lat: 42.35843, lon: -71.05977, hasResults: False
protocolSection identificationModule nctId: NCT06338085, orgStudyIdInfo id: meryemvrlshn00000000002, briefTitle: The Effect of Emotional Freedom Technique (EFT) on Depression in Postmenopausal Women, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-11, primaryCompletionDateStruct date: 2024-05-04, completionDateStruct date: 2024-05-20, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Meryem Vural Şahin, class: OTHER, descriptionModule briefSummary: The aim of this study is to determine the effect of EFT (Emotional Freedom Technique), a nonpharmacological method, on menopausal symptoms and depression in postmenopausal women. By determining the effectiveness of the Emotional Freedom Technique, the applicability of non-pharmacological method treatment in women with depression and menopausal symptoms in postmenopausal period will be proven. As a result of the study, if a positive effect on menopausal symptoms and depression is found in women with EFT, it can be recommended as an evidence-based alternative method in midwifery and nursing care., conditionsModule conditions: Menopause, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: the groups with a conventional therapy control group, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: emotional liberation technique, outcomesModule primaryOutcomes measure: Beck Depression Scale, secondaryOutcomes measure: Menopause Rating Scale (MRS), eligibilityModule sex: FEMALE, maximumAge: 65 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: family health center no. 1 in Çayyolu, status: RECRUITING, city: Ankara, state: Çankaya, country: Turkey, contacts name: MERYEM VURAL ŞAHİN, role: CONTACT, phone: 05535344779, email: meryemyasam@gmail.com, contacts name: Meltem UĞURLU, role: PRINCIPAL_INVESTIGATOR, contacts name: Derya Yüksel KOÇAK, role: SUB_INVESTIGATOR, geoPoint lat: 39.91987, lon: 32.85427, hasResults: False
protocolSection identificationModule nctId: NCT06338072, orgStudyIdInfo id: DIABETEXX/1, briefTitle: Impact of the Menstrual Cycle in Reproductive Aged Women With Type 1 Diabetes Using a Closed Loop System (DIABETEXX/1)., acronym: DIABETEXX/1, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-03-03, primaryCompletionDateStruct date: 2025-01-01, completionDateStruct date: 2025-08-01, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal, class: OTHER, collaborators name: Universitat Politècnica de València, descriptionModule briefSummary: The aim of this observational study is to assess the effectiveness of automatic insulin infusion in responding to changes in insulin sensitivity throughout various phases of the menstrual cycle in a cohort of reproductive-aged women with type 1 diabetes, using an advanced closed-loop system. By gaining insights into both the limitations and effectiveness of this adaptation, we aim to inform the enhancement of control algorithms and learning strategies within closed-loop systems. This research is especially vital for addressing the distinct challenges that women commonly encounter in maintaining glycemic control., conditionsModule conditions: Type 1 Diabetes, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 119, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Time in range, secondaryOutcomes measure: Time below range, secondaryOutcomes measure: Time above range, secondaryOutcomes measure: Caloric intake, secondaryOutcomes measure: Temperature, secondaryOutcomes measure: Photoplethysmography, secondaryOutcomes measure: Accelerometry, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule locations facility: Lía Nattero-Chávez, city: Madrid, zip: 28034, country: Spain, geoPoint lat: 40.4165, lon: -3.70256, hasResults: False
protocolSection identificationModule nctId: NCT06338059, orgStudyIdInfo id: Gulcanozturkchatipchousein, briefTitle: Relationship Between Vitamin D and Vitamin B12 Levels and Neuropathic Pain in Lipedema, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-05-01, completionDateStruct date: 2024-06-01, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: Fatih Sultan Mehmet Training and Research Hospital, class: OTHER, descriptionModule briefSummary: Lipedema is a disease characterized by bilateral abnormal fat deposition in the upper and lower extremities. Pain is a common symptom in lipedema.Vitamin D plays an important role in chronic pain. Vitamin B have analgesic role in some neuropathic pain conditions.This study aimedto evaluate the relationship between vitamin D and vitamin B12 levels and neuropathic pain in lipedema., conditionsModule conditions: Vitamin D Deficiency, conditions: B12 Deficiency Vitamin, conditions: Lipedema, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 200, type: ACTUAL, armsInterventionsModule interventions name: Vitamin B12 Level, outcomesModule primaryOutcomes measure: Vitamin B12 Level, primaryOutcomes measure: 25 OH Vitamin D Level, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Gulcan Ozturk, city: Istanbul, zip: 34752, country: Turkey, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06338046, orgStudyIdInfo id: EAShi23M01, briefTitle: In Vivo Evaluation of NC65 - Vita D-Light SKIN ADAPTOGEN AND SEBUM BALANCE EFFICACY, acronym: Shitake, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-10-01, primaryCompletionDateStruct date: 2023-11-15, completionDateStruct date: 2023-12-22, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: Ritamaria Di Lorenzo, class: OTHER, descriptionModule briefSummary: This double-blind placebo-controlled study intends to confirm skin adaptogen and sebum balance efficacy of the investigational active ingredient NC65 - Vita D-Light, transmitted at 0.5% w/w in a topical cosmetic formulation, on a panel of healthy human subjects.The study is performed by RD Cosmetics - University of Naples Federico II, from October to June 2024. The study involves female and male subjects, scheduled for eligibility screening at the study site. A total of 40 subjects were enrolled, and randomly divided into 2 groups: 20 subjects received the active treatment (cosmetic formulation with 0.5 %w/w NC65 - Vita D-Light) and 20 subjects the placebo one.The cosmetic effectiveness of the products was instrumentally detected, using innovative, non-invasive and worldwide recognized devices for skin analysis, like:* Corneometer CM 825 (C+K electronic GmbH) detects water's content of the stratum corneum.* Tewameter® TM Hex (C+K electronic GmbH) detects the trans-epidermal water loss (TEWL).* Sebumeter SM 815 accurately and reproducibly measures the level of sebum on the skin surface.* Visia VISIA® (Canfield Scientific, Inc.) for skin surface assessment.The monitored skin features parameters will be check after 1 hour (T1h) for the adaptogen test, and after 7, 14 and 28 days (T7 -T14-T28), for the detox test. Panelists will complete the self-assessment questionnaire at the end of the study period (T28)., conditionsModule conditions: SKIN ADAPTOGEN AND SEBUM BALANCE EFFICACY, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: 2 parallel arm, double blind, randomized, placebo-controlled, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, maskingDescription: neither the patient nor the investigator knows who is getting which treatment., whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 40, type: ACTUAL, armsInterventionsModule interventions name: Corthellus Shiitake(Mushroom) Extract, interventions name: Placebo, outcomesModule primaryOutcomes measure: Soothing Test, secondaryOutcomes measure: Detox and adaptogen Test, eligibilityModule sex: ALL, minimumAge: 25 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: RD Cosmetics Lab - Pharmacy Department, University of Naples Federico II, city: Naples, zip: 80131, country: Italy, geoPoint lat: 40.85216, lon: 14.26811, hasResults: False
protocolSection identificationModule nctId: NCT06338033, orgStudyIdInfo id: 2024-03-23, briefTitle: Prognostic Study of Visceral Fat and Heart Failure With Preserved Ejection Fraction, statusModule overallStatus: COMPLETED, startDateStruct date: 2020-09-19, primaryCompletionDateStruct date: 2023-08-28, completionDateStruct date: 2023-11-30, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: Chongqing Medical University, class: OTHER, descriptionModule briefSummary: Obesity and heart failure with preserved ejection fraction (HFpEF) have multiple pathologic associations that affect the prognosis of HFpEF. Chinese people are more prone to visceral obesity, resulting in varying degrees of true obesity in individuals with the same body mass index (BMI). There are no prognostic studies of VFA/BMI in the HFpEF population., conditionsModule conditions: Heart Failure With Preserved Ejection Fraction and Visceral Fat, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 298, type: ACTUAL, armsInterventionsModule, outcomesModule primaryOutcomes measure: All-cause mortality, secondaryOutcomes measure: Rehospitalization for heart failure, otherOutcomes measure: Composite endpoints of all-cause mortality and rehospitalization for heart failure, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The First Affiliated Hospital of Chongqing Medical University, city: Chongqing, country: China, geoPoint lat: 29.56278, lon: 106.55278, hasResults: False
protocolSection identificationModule nctId: NCT06338020, orgStudyIdInfo id: RHPT/0022/0042, briefTitle: Adaptive Variable-Resistance Training in Pediatric Survivors of Acute Lymphoblastic Leukemia, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-12-29, primaryCompletionDateStruct date: 2024-01-04, completionDateStruct date: 2024-01-04, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: This study was designed to investigate the effect of eight weeks of adaptive variable-resistance training (Adaptive-VRT) on chemotherapy-induced sarcopenia, fatigue, and functional restrictions in a convenience sample of pediatric survivors of acute lymphoblastic leukemia (ALL). Sixty-two pediatric survivors of ALL were randomly allocated to the experimental group (n = 31, received the adaptive variable-resistance training) or the Control group (n = 31, received standard physical therapy care). Both groups were assessed for muscle mass, strength, fatigue, and functional capacity before and after treatment., conditionsModule conditions: Acute Lymphoblastic Leukemia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: A prospective, dual-arm, randomized controlled trial, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: This was a single-blind protocol. The researcher who collected the data was blind to the allocation of treatment., whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 62, type: ACTUAL, armsInterventionsModule interventions name: Adaptive variable-resistance training, interventions name: Standard physical therapy, outcomesModule primaryOutcomes measure: Thigh muscle thickness, primaryOutcomes measure: Muscle strength, secondaryOutcomes measure: Fatigue, secondaryOutcomes measure: Six-minute walk test, secondaryOutcomes measure: 4x10 meter Shuttle Run test, secondaryOutcomes measure: Timed up and down stairs test, eligibilityModule sex: ALL, minimumAge: 12 Years, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Ragab K. Elnaggar, city: Al Kharj, state: Riyadh, country: Saudi Arabia, geoPoint lat: 24.15541, lon: 47.33457, hasResults: False
protocolSection identificationModule nctId: NCT06338007, orgStudyIdInfo id: 2012-KAEK-15/2702, briefTitle: Relationship Between Hand Dynamometer Measurements, PFT, and mFI With Postoperative Outcomes, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2024-09-01, completionDateStruct date: 2025-01-01, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Atatürk Chest Diseases and Chest Surgery Training and Research Hospital, class: OTHER, descriptionModule briefSummary: The study will take place at SBÜ Ankara Atatürk Sanatorium Training and Research Hospital and will include 100 patients over the age of 40 who are scheduled for lung malignancy surgery after 01 April 2024. Informed consent will be obtained from all patients, who will be assigned a number from 1 to 100.For patients over 40 years of age who are scheduled to undergo lung malignancy resection surgery, demographic data including age, gender, height, weight, body mass index (BMI), diagnosis, comorbidities, and ASA (American Society of Anaesthesiologist) score will be recorded. In addition, hand grip strength measurement, pulmonary function test, and modified frailty index (a scoring system that includes 11 parameters) will be recorded prior to surgery. Intraoperative and postoperative complications will be documented. The duration of the patient's stay in the intensive care unit, chest tube removal, length of hospital stay, and postoperative complications will also be recorded. A follow-up call will be made to the patient by the responsible researcher 90 days after the operation to inquire about any complications that may have developed within that time frame.The study aims to investigate the relationship between preoperative hand grip strength measurement, pulmonary function test analysis (PFT), and modified frailty index with the duration of intensive care unit stay, chest tube withdrawal time, hospital stay, and postoperative complications in patients undergoing lung resection due to malignancy., conditionsModule conditions: Complication,Postoperative, conditions: Lung Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Hand Dynamometer, interventions name: Pulmonary Function Test, interventions name: Modified Frailty Index, outcomesModule primaryOutcomes measure: Complication, eligibilityModule sex: ALL, minimumAge: 40 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ankara Atatürk Sanatorium Training and Research Hospital, city: Ankara, state: Keçiören, zip: 06290, country: Turkey, contacts name: Gülay ÜLGER, specialist, role: CONTACT, phone: 05059532122, phoneExt: +9, email: gulayulger@gmail.com, contacts name: Onur KÜÇÜK, specialist, role: SUB_INVESTIGATOR, geoPoint lat: 39.91987, lon: 32.85427, hasResults: False
protocolSection identificationModule nctId: NCT06337994, orgStudyIdInfo id: AUH-Neurol-TBI_2024, briefTitle: Memantine Hydrochloride for Treatment of Cognitive Dysfunction Due to Traumatic Brain Injury, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2024-06-01, completionDateStruct date: 2024-12-30, studyFirstPostDateStruct date: 2024-03-29, lastUpdatePostDateStruct date: 2024-03-29, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: Posttraumatic consequences are common causes of disability and long-term morbidity. They include cognitive dysfunction, seizures, headache, dizziness, fatigue, sensory deficits, neurodegeneration and psychiatric disorders (e.g. posttraumatic stress disorder, depression, anxiety, etc). Diffuse axonal injury and disruption of normal neuronal function are the most common and important pathologic features of traumatic primary closed head injury. depression, anxiety, etc). Excitotoxicity and apoptosis caused by activation of N-methyl-D-aspartate (NMDA) glutamate receptors, are two main suggested mechanisms of traumatic neuronal cell death and posttraumtic neurologic adverse consequences. Experimental and clinical studies have demonstrated that memantine hydrochloride, NMDA-type glutamate receptor antagonist, could have beneficial effect in treatment of posttraumatic cognitive dysfunction. Memantine may contribute to cognitive improvements in TBI by decreasing the synaptic 'noise' resulting from excessive NMDA receptor activation, inhibition of β-amyloid mediated toxicity and readjustment of the balance between inhibition and excitation on neuronal networks in the central nervous system (CNS)., conditionsModule conditions: Treatment of Posttraumatic Cognitive Dysfunction, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: parallel assignment, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Memantine Hydrochloride, outcomesModule primaryOutcomes measure: The severity of traumatic brain injury (TBI), primaryOutcomes measure: The symptoms of depression, primaryOutcomes measure: The symptoms of anxiety, primaryOutcomes measure: The cognitive function, secondaryOutcomes measure: Quality of life, secondaryOutcomes measure: The cognitive function, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule locations facility: Assiut University, Faculty of Medicine, Hospital of Neurology, Psychiatry and Neurosurgery, status: RECRUITING, city: Assiut, zip: 71516, country: Egypt, contacts name: Sherifa A Hamed, M.D., role: CONTACT, phone: +201115324560, email: hamedsherifa@aun.edu.eg, contacts name: Sherifa A Hamed, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 27.18096, lon: 31.18368, hasResults: False