hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06343324, orgStudyIdInfo id: 2023/012, briefTitle: Effect of Web-Based Adaptation and Insomnia Severity in Individuals Using Noninvasive Ventilators at Home, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2024-02-01, completionDateStruct date: 2024-04-01, studyFirstPostDateStruct date: 2024-04-02, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: KTO Karatay University, class: OTHER, descriptionModule briefSummary: Home use of the NIV device, which is used to manage respiratory failure, one of the most disturbing symptoms due to COPD, will continue to increase. There is a need for studies evaluating the effectiveness of the use of WEB-based training programs in making patients and their families independent in the use of this device. This study will produce evidence for this effect and contribute to the awareness of healthcare professionals working in this field. The WEB-based training module to be developed aims to increase compliance with NIV in patients using NIV at home for a long time and to manage symptoms such as insomnia that may develop due to NIV., conditionsModule conditions: Noninvasive Ventilation, conditions: COPD, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Web-based education, outcomesModule primaryOutcomes measure: Patient Identifiable Characteristics Form, secondaryOutcomes measure: S³-NIV Questionnaire, otherOutcomes measure: insomnia severity index, otherOutcomes measure: Expected behavioral changes in the individual survey, eligibilityModule sex: ALL, minimumAge: 50 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Health Sciences University Konya Beyhekim Training and Research Hospital, city: Konya, state: Selçuklu, zip: 42060, country: Turkey, geoPoint lat: 37.87135, lon: 32.48464, hasResults: False
protocolSection identificationModule nctId: NCT06343298, orgStudyIdInfo id: ES_MANP_2001, briefTitle: To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-07-01, primaryCompletionDateStruct date: 2025-07-01, completionDateStruct date: 2025-08-01, studyFirstPostDateStruct date: 2024-04-02, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: E-Star BioTech, LLC, class: INDUSTRY, collaborators name: Mayo Clinic, collaborators name: PPD, descriptionModule briefSummary: This is a Phase 2 dose-titration study designed to evaluate the safety and efficacy of MANP subcutaneous injection compared to placebo in reducing baseline daytime systolic blood pressure (SBP), derived from 24-hour ambulatory blood pressure monitoring (ABPM), in subjects with hypertension who are taking 3 or more antihypertensive medications with different mechanisms of action., conditionsModule conditions: Difficult to Control Hypertension, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 132, type: ESTIMATED, armsInterventionsModule interventions name: MANP, interventions name: Placebo Matched control, outcomesModule primaryOutcomes measure: Change from baseline in mean daytime SBP derived from 24-hour ABPM at approximately Day 42., primaryOutcomes measure: Incidence and severity of Adverse events through 4- weeks post end of treatment., primaryOutcomes measure: Incidence and severity of Serious Adverse Events through 4- weeks post end of treatment., primaryOutcomes measure: Incidence and severity of Treatment Emergent Adverse Events through 4- weeks post end of treatment., secondaryOutcomes measure: Change in Clinic sitting systolic blood pressure, secondaryOutcomes measure: Pharmacokinetics - Cmax, secondaryOutcomes measure: Pharmacokinetics - Tmax, secondaryOutcomes measure: Anti-drug Antibody, otherOutcomes measure: Differential Outcomes in African-American Subject versus Non-African American Subjects, otherOutcomes measure: Metabolic biomarkers - Glucose, otherOutcomes measure: Metabolic biomarkers - Insulin, otherOutcomes measure: Metabolic biomarkers - HbA1C, otherOutcomes measure: Lipid biomarkers - HDL, otherOutcomes measure: Lipid biomarkers - LDL, otherOutcomes measure: Lipid biomarkers - TG, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06343285, orgStudyIdInfo id: 20231215, briefTitle: Upper Limb Tremor Reduction in Essential Tremor Patients, acronym: ULTRE, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2024-05, completionDateStruct date: 2024-06, studyFirstPostDateStruct date: 2024-04-02, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Encora, Inc., class: INDUSTRY, descriptionModule briefSummary: This study is designed to demonstrate the safety and tolerability of the Encora Therapeutics Tremor Mitigation Device in subjects with upper limb tremor caused by Essential Tremor., conditionsModule conditions: Essential Tremor, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: SEQUENTIAL, interventionModelDescription: Three different arms in a randomized order, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, maskingDescription: Randomization schedule maintained by non-Clinical personnel, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Encora Therapeutics Tremor Reduction Device, outcomesModule primaryOutcomes measure: Tolerability, primaryOutcomes measure: Safety, secondaryOutcomes measure: Bain & Findley Activity of Daily Living (BF-ADL) #2, secondaryOutcomes measure: BF-ADL #4, secondaryOutcomes measure: BF-ADL #17, secondaryOutcomes measure: BF-ADL #21, secondaryOutcomes measure: Patient Global Impression of Change (PGI-C), secondaryOutcomes measure: Clinician Global Impression of Change (CGI-C), secondaryOutcomes measure: Tremor power as measured by gyroscope, otherOutcomes measure: The Essential Tremor Rating Scale (TETRAS) #2.4, otherOutcomes measure: TETRAS #2.6, otherOutcomes measure: TETRAS #2.8, otherOutcomes measure: Patient Global Impression of Severity (PGI-S), otherOutcomes measure: Clinician Global Impression of Severity (CGI-S), otherOutcomes measure: Tremor power as measured by accelerometer, eligibilityModule sex: ALL, minimumAge: 22 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Encora Therapeutics, status: RECRUITING, city: Cambridge, state: Massachusetts, zip: 02139, country: United States, contacts name: Kristi Winterfeldt, MSHS, role: CONTACT, phone: 763-248-1210, email: kristi@encoratherapeutics.com, contacts name: Taylor Robertson, role: CONTACT, phone: 7814221105, email: taylor@encoratherapeutics.com, contacts name: Kristi Winterfeldt, MSHS, role: PRINCIPAL_INVESTIGATOR, contacts name: Fatta Nahab, MD, role: SUB_INVESTIGATOR, geoPoint lat: 42.3751, lon: -71.10561, hasResults: False
protocolSection identificationModule nctId: NCT06343272, orgStudyIdInfo id: LEGO, briefTitle: Lymphocyte Enhancement in Gastroenteric Oncology, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-03-22, primaryCompletionDateStruct date: 2024-12-22, completionDateStruct date: 2025-02-28, studyFirstPostDateStruct date: 2024-04-02, lastUpdatePostDateStruct date: 2024-04-03, sponsorCollaboratorsModule leadSponsor name: Fondazione IRCCS Policlinico San Matteo di Pavia, class: OTHER, collaborators name: University of Pavia, descriptionModule briefSummary: LEGO is single center double-blind randomized trial aimed at testing the efficacy of an essential ammino acid (EAA) supplementation in improving the absolute count of peripheral lymphocytes and the tolerance to chemotherapy in patients with advanced gastrointestinal malignancies not candidates to immune check-point inhibitors containing regimens., conditionsModule conditions: Advanced Gastrointestinal Cancers, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 54, type: ESTIMATED, armsInterventionsModule interventions name: EAA supplementation, interventions name: Isocaloric placebo, outcomesModule primaryOutcomes measure: Exit from lymphopenia, secondaryOutcomes measure: The change in the % of lymphocytes over time, secondaryOutcomes measure: The proportion of patients with G3-G5 toxicity, secondaryOutcomes measure: The percentage of chemotherapy dose administered compared to that expected for the patients., secondaryOutcomes measure: plasma aminoacids composition chang during treatment, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: IRCCS Policlinico San Matteo, status: RECRUITING, city: Pavia, zip: 27100, country: Italy, contacts name: Alessandra Ferrari, role: CONTACT, phone: 0382.503689, phoneExt: +39, email: alessandra.ferrari@smatteo.pv.it, contacts name: Salvatore Corallo, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 45.19205, lon: 9.15917, hasResults: False
protocolSection identificationModule nctId: NCT06343259, orgStudyIdInfo id: 2534, briefTitle: The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-08-01, completionDateStruct date: 2024-08-14, studyFirstPostDateStruct date: 2024-04-02, lastUpdatePostDateStruct date: 2024-04-02, sponsorCollaboratorsModule leadSponsor name: Sisli Hamidiye Etfal Training and Research Hospital, class: OTHER, descriptionModule briefSummary: In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery. Cardiovascular events are a leading cause of mortality and morbidity following non-cardiac surgery, with myocardial injury after non-cardiac surgery (MINS) being a significant concern. MINS, characterized by asymptomatic elevation of troponin levels without accompanying ECG findings, is closely associated with postoperative mortality. With the increasing prevalence of comorbidities in the elderly population and the rising frequency of non-cardiac surgeries in this demographic, understanding the effects of different anesthesia types on postoperative myocardial injury is crucial., conditionsModule conditions: Myocardial Injury After Non-cardiac Surgery, conditions: Hypotension During Surgery, conditions: Anesthesia, General, conditions: Anesthesia, Spinal, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: General Anesthesia, interventions name: Spinal Anesthesia, outcomesModule primaryOutcomes measure: Myocardial Injury After Non-Cardiac Surgery (MINS), secondaryOutcomes measure: The duration of intensive care unit (ICU) stay, secondaryOutcomes measure: The duration of hospital stay, eligibilityModule sex: ALL, minimumAge: 65 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Sisli Hamidiye Etfal Training and Research Hospital, city: Istanbul, zip: 34396, country: Turkey, contacts name: Mustafa Bilgehan AYIK, role: CONTACT, phone: +905377247984, email: drbilgehanayik@gmail.com, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06343246, orgStudyIdInfo id: MustafaKemalU, briefTitle: Functional Inspiratory Muscle Training in Patients Diagnosed With Hypertension, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-05-01, primaryCompletionDateStruct date: 2024-03-30, completionDateStruct date: 2024-03-30, studyFirstPostDateStruct date: 2024-04-02, lastUpdatePostDateStruct date: 2024-04-02, sponsorCollaboratorsModule leadSponsor name: Mustafa Kemal University, class: OTHER, descriptionModule briefSummary: This study was planned to investigate the effectiveness of combined exercise training, that is, functional inspiratory muscle training, with breathing exercises to be applied with a portable, easy-to-use respiratory muscle strengthening device, on exercise capacity and peripheral muscle strength., conditionsModule conditions: Hypertension,Essential, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Prospective Randomized Controlled Study, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 45, type: ESTIMATED, armsInterventionsModule interventions name: Inspiratory muscle training with device, outcomesModule primaryOutcomes measure: Change of the exercise capacity from baseline to 8 week, primaryOutcomes measure: Change of the peripheral muscle strenght from baseline to 8 week, primaryOutcomes measure: change of the upper extremity exercise capacity from baseline to 8 week, secondaryOutcomes measure: change of the postural balance from baseline to 8 week, secondaryOutcomes measure: change of the physical activity from baseline to 8 week, secondaryOutcomes measure: change of the quality of life from baseline to 8 week, secondaryOutcomes measure: change of the Fev1/Fvc, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hatay Mustafa Kemal University, status: RECRUITING, city: Hatay, state: Antakya, country: Turkey, contacts name: İrem hüzmeli, role: CONTACT, email: fztirem@gmail.com, geoPoint lat: 38.40227, lon: 27.10486, hasResults: False
protocolSection identificationModule nctId: NCT06343220, orgStudyIdInfo id: AWARE 2.0, briefTitle: Project AWARE 2.0 to Improve Awareness, Willingness and Ability for Research and Enrollment in Clinical Research, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-10, primaryCompletionDateStruct date: 2024-09, completionDateStruct date: 2024-09, studyFirstPostDateStruct date: 2024-04-02, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: Huntington Study Group, class: NETWORK, collaborators name: Roche Products Limited, descriptionModule briefSummary: The Project AWARE 2.0 Survey is intended to gain knowledge about the feelings, attitudes, and beliefs of HD family members, care partners and others affected by HD towards the way drug trials and observational studies are communicated and conducted., conditionsModule conditions: Huntington Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 600, type: ESTIMATED, outcomesModule primaryOutcomes measure: Examine awareness, primaryOutcomes measure: Provide the HD research community with the insight., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Huntington Study Group, status: RECRUITING, city: Rochester, state: New York, zip: 14618, country: United States, contacts name: Elise Kayson, MS, role: CONTACT, phone: 800-487-7671, email: info@myhdstory.org, geoPoint lat: 43.15478, lon: -77.61556, hasResults: False
protocolSection identificationModule nctId: NCT06343207, orgStudyIdInfo id: 249637, briefTitle: Percussive Therapy Reduced EMG Activity During Calf Raise in Limbs With and Without Chronic Ankle Instability, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-11-22, primaryCompletionDateStruct date: 2023-02-02, completionDateStruct date: 2023-02-02, studyFirstPostDateStruct date: 2024-04-02, lastUpdatePostDateStruct date: 2024-04-02, sponsorCollaboratorsModule leadSponsor name: Charles University, Czech Republic, class: OTHER, descriptionModule briefSummary: To examine the acute effect of percussive therapy on peak calf muscle activation during standing heel raise in subjects with and without chronic ankle instability (CAI)., conditionsModule conditions: Ankle Injuries, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: A Randomized Controlled Trial, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: SINGLE, whoMasked: INVESTIGATOR, enrollmentInfo count: 39, type: ACTUAL, armsInterventionsModule interventions name: Percussive massage gun therapy, outcomesModule primaryOutcomes measure: Percussive Therapy Reduced EMG Activity During Calf Raise in Limbs With and Without Chronic Ankle Instability., eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 30 Years, stdAges: ADULT, contactsLocationsModule locations facility: Faculty of physical education and sport, Charles University, city: Praha, zip: 16252, country: Czechia, geoPoint lat: 50.08804, lon: 14.42076, hasResults: False
protocolSection identificationModule nctId: NCT06343194, orgStudyIdInfo id: 6162, briefTitle: Changes in Electromyographic Activity in Aligner Treatment of Adult Patients With and Without Nocturnal Bruxism, acronym: EMG_BRUX, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-02-09, primaryCompletionDateStruct date: 2024-05-31, completionDateStruct date: 2024-12-22, studyFirstPostDateStruct date: 2024-04-02, lastUpdatePostDateStruct date: 2024-04-11, sponsorCollaboratorsModule leadSponsor name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, class: OTHER, descriptionModule briefSummary: The purpose of the study is to evaluate the effectiveness of clear aligners on the symptoms and signs reported by bruxism patients.The aim of the investigators is to evaluate the effect of treatment on the masticatory muscles and the changes related to the tropism of the masseter muscles using Bruxoff ® device, before and after the beginning of the therapy. Bruxoff ® is a holter that assesses the contractions of the masseter muscles and the heart during sleep.The plan is to compare treatment with clear aligners for bruxism and non-bruxism patients.The results will allow the investigators to evaluate the progress of clear aligner therapy in bruxism patients and compare them with those of non-bruxism patients., conditionsModule conditions: Sleep Bruxism, conditions: Masseter Muscle Hypertrophy, conditions: Grinding Teeth, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: bruxism patients and non-bruxism patients, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 22, type: ESTIMATED, armsInterventionsModule interventions name: Bruxoff ®, outcomesModule primaryOutcomes measure: Change in potentials recorded by Bruxoff ® in bruxism patients., secondaryOutcomes measure: Change of signs and symptoms of bruxism, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule locations facility: UOC Odontoiatria Generale e Ortodonzia, Policlinico Agostino Gemelli Università Cattolica del Sacro Cuore, status: RECRUITING, city: Rome, state: Lazio, zip: 00168, country: Italy, contacts name: Massimo Cordaro, professor, role: CONTACT, phone: +39 0630154286, email: massimo.cordaro@unicatt.it, geoPoint lat: 41.89193, lon: 12.51133, hasResults: False
protocolSection identificationModule nctId: NCT06343181, orgStudyIdInfo id: IEO 1824, briefTitle: A Qualitative Study on Treatment Adherence in Patients With Metastatic Breast Cancer, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-10-03, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-04-02, lastUpdatePostDateStruct date: 2024-04-02, sponsorCollaboratorsModule leadSponsor name: European Institute of Oncology, class: OTHER, descriptionModule briefSummary: Qualitative observational study with the aim to explore medication adherence in a sample of patients with metastatic breast cancer.Patients with metastatic breast cancer receiving or having received oral oncologic therapy, and attending the Division of Medical Senology at the European Institute of Oncology, will be included and enrolled in this research project.", conditionsModule conditions: Metastatic Breast Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Evaluation of factors influencing patients' adherence to medical therapy, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: European Institute of Oncology, status: RECRUITING, city: Milan, country: Italy, contacts name: Gabriella Pravettoni, role: CONTACT, geoPoint lat: 45.46427, lon: 9.18951, hasResults: False
protocolSection identificationModule nctId: NCT06343168, orgStudyIdInfo id: frailty, briefTitle: Prevalence of Frailty and Associated Factors in Coronary Artery Bypass Patients, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-02-18, primaryCompletionDateStruct date: 2022-02-18, completionDateStruct date: 2022-02-18, studyFirstPostDateStruct date: 2024-04-02, lastUpdatePostDateStruct date: 2024-04-02, sponsorCollaboratorsModule leadSponsor name: Uşak University, class: OTHER, descriptionModule briefSummary: This study aimed to determine the prevalence of and factors affecting frailty in patients with coronary artery bypass graft.The main question it aims to answer are:What are the prevalence of and factors affecting frailty in patients with coronary artery bypass graft Type of study: descriptive cross-sectional study Participant population: coronary artery bypass grafting patients, conditionsModule conditions: Frailty, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 96, type: ACTUAL, armsInterventionsModule interventions name: prevalence of frailty, outcomesModule primaryOutcomes measure: Prevalence of frailty, secondaryOutcomes measure: Activities of Daily Living, secondaryOutcomes measure: Nutritional Assessment, secondaryOutcomes measure: Comorbidity, secondaryOutcomes measure: Cognitive Assessment, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Usak University, city: Usak, state: Center, zip: 64200, country: Turkey, geoPoint lat: 38.67351, lon: 29.4058, hasResults: False