protocolSection identificationModule nctId: NCT06263868, orgStudyIdInfo id: 69HCL23_1090, secondaryIdInfos id: 2023-A02313-42, type: OTHER, domain: ID-RCB, briefTitle: First Observatory of Precocious Puberty., acronym: PAPPEL, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2028-03-01, completionDateStruct date: 2028-03-01, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: Hospices Civils de Lyon, class: OTHER, descriptionModule briefSummary: The age of puberty has fluctuated throughout history. Recent data shows an increase in the age of onset of puberty signs, in the United States but also in Europe. A recent Public Health France study published in 2018 reports an increase in the incidence of precocious puberty with geographical heterogeneity. The consequences of these appearances include the early onset of menarche, short adult height and the psychological impact.Due to a lack of studies and additional data, the reasons for this development are difficult to understand. Among current hypotheses, the entanglement with the evolution of our environment is at the forefront: the action of environmental endocrine disruptors and nutritional factors could play a role in the process of early appearance of pubertal signs.The establishment of a national observatory for early and advanced puberty in collaboration with pediatric endocrinologists (on the front line) would allow a reliable and precise field approach, capable of supplementing epidemiological data, which are currently insufficient.The investigators hypothesize that the establishment of an observatory of pubertal advances (early puberty and advanced puberty) in private medicine is possible, with inclusion of at least 75% of eligible patients, and collection of at least 80% of data., conditionsModule conditions: Puberty, Precocious, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 3360, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Number of recruited patients with at least 80% of the main data collected, primaryOutcomes measure: Missing data rate, primaryOutcomes measure: At least 75% of patients included, eligibilityModule sex: ALL, maximumAge: 11 Years, stdAges: CHILD, contactsLocationsModule locations facility: Clinique du Val d'Ouest, city: Ecully, state: Auvergne-Rhône-Alpes, zip: 69130, country: France, contacts name: Emilie Doye, MD, role: CONTACT, phone: 0472118890, phoneExt: 33, email: emilie.doye@chu-lyon.fr, contacts name: Emilie Doye, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 45.77726, lon: 4.77481, locations facility: Clinique du Val d'Ouest, city: Ecully, state: Auvergne-Rhône-Alpes, zip: 69130, country: France, contacts name: Emilie Beaufils, MD, role: CONTACT, phone: 0658187556, phoneExt: 33, email: pediatre.beaufils@gmail.com, contacts name: Emilie Beaufils, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 45.77726, lon: 4.77481, locations facility: Clinique du Val d'Ouest, city: Ecully, state: Auvergne-Rhône-Alpes, zip: 69130, country: France, contacts name: Mélanie Daval Cote, MD, role: CONTACT, phone: 0472193310, phoneExt: 33, email: drdavalcote@yahoo.fr, contacts name: Mélanie Daval Cote, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 45.77726, lon: 4.77481, locations facility: Pediatric practice, city: Lyon, state: Auvergne-Rhône-Alpes, zip: 69006, country: France, contacts name: Prisca DEALBERTI, MD, role: CONTACT, phone: 04 72 83 50 01, phoneExt: 33, email: dr.dealberti@gmail.com, contacts name: Prisca DEALBERTI, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 45.74848, lon: 4.84669, locations facility: Clinique Saint jean, city: Lyon, state: Auvergne-Rhône-Alpes, zip: 69008, country: France, contacts name: Aude Mariani Ecochard, MD, role: CONTACT, phone: 0681560894, phoneExt: 33, email: docteurmariani@yahoo.com, contacts name: Aude Mariani Ecochard, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 45.74848, lon: 4.84669, locations facility: Pediatric practice, city: Rennes, state: Bretagne, zip: 35200, country: France, contacts name: Livie CHATELAIS, MD, role: CONTACT, phone: 02 99 86 77 57, phoneExt: 33, email: lchatelais@yahoo.fr, contacts name: Livie CHATELAIS, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 48.11198, lon: -1.67429, locations facility: Pediatric practice, city: Chambray-lès-Tours, state: Centre-Val De Loire, zip: 37170, country: France, contacts name: Caroline HASSELMAN, MD, role: CONTACT, phone: 02 46 65 07 45, phoneExt: 33, email: chasselmann@mac.com, contacts name: Caroline HASSELMAN, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 47.33537, lon: 0.70286, locations facility: Pediatric practice, city: Essey-lès-Nancy, state: Grand Est, zip: 54270, country: France, contacts name: Julie AUGER, MD, role: CONTACT, phone: 03 83 21 01 11, phoneExt: 33, email: dr.augerjulie@gmail.com, contacts name: Julie AUGER, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 48.70179, lon: 6.22425, locations facility: Pediatric practice, city: Levallois-Perret, state: Hauts-de-Seine, zip: 92300, country: France, contacts name: Delphine ZENATY, MD, role: CONTACT, phone: 01 70 83 61 23, phoneExt: 33, email: delphine.revco@gmail.com, contacts name: Delphine ZENATY, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 48.89389, lon: 2.28864, locations facility: Pediatric practice, city: Paris, state: Ile-de-France, zip: 75116, country: France, contacts name: Mélanie AMOUYAL, MD, role: CONTACT, phone: 01 45 25 70 11, phoneExt: 33, email: dramouyal.endocrinoped@gmail.com, contacts name: Mélanie AMOUYAL, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 48.85341, lon: 2.3488, locations facility: Pediatric practice, city: Fondettes, state: Indre-et-Loire, zip: 37230, country: France, contacts name: Myriam BOUILLO, MD, role: CONTACT, phone: 02 47 66 45 52, phoneExt: 33, email: myriam.bouillo@orange.fr, contacts name: Myriam BOUILLO, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 47.4035, lon: 0.59686, locations facility: Polyclinique Bordeaux rive droite, city: Lormont, state: Nouvelle-Aquitaine, zip: 33310, country: France, contacts name: Aurélie LACOSTE RODRIGUE, MD, role: CONTACT, email: dr.aurelielacoste@free.fr, contacts name: Aurélie LACOSTE RODRIGUE, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 44.87495, lon: -0.51782, locations facility: Pediatric practice, city: Pau, state: Nouvelle-Aquitaine, zip: 64000, country: France, contacts name: Catie CESSANS, MD, role: CONTACT, phone: 06 15 82 62 59, phoneExt: 33, email: pediatre.cessans@gmail.com, contacts name: Catie CESSANS, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 43.3, lon: -0.36667, locations facility: Pediatric Practice, city: Pessac, state: Nouvelle-Aquitaine, zip: 33600, country: France, contacts name: Olivier PUEL, MD, role: CONTACT, phone: 0556453585, phoneExt: 33, email: opuel@free.fr, contacts name: Olivier PUEL, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 44.81011, lon: -0.64129, locations facility: Clinique rive gauche, city: Toulouse, state: Occitanie, zip: 31300, country: France, contacts name: Adelaïde DURAND, MD, role: CONTACT, phone: 05 67 77 51 31, phoneExt: 33, email: dr.durand@cliniquerivegauche.fr, contacts name: Adelaïde DURAND, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 43.60426, lon: 1.44367, locations facility: Pediatric practice, city: Saint-Nazaire, state: Pays De La Loire, zip: 44600, country: France, contacts name: Isabelle GUEMAS, MD, role: CONTACT, phone: 02 40 53 88 91, phoneExt: 33, email: isabelleguemas@gmail.com, contacts name: Isabelle GUEMAS, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 47.28333, lon: -2.2, locations facility: Pediatric practice, city: Trélazé, state: Pays De La Loire, zip: 49800, country: France, contacts name: Julie CHEIGNON, MD, role: CONTACT, phone: 02 41 79 08 09, phoneExt: 33, email: julie.cheignon@wanadoo.fr, contacts name: Julie CHEIGNON, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 47.44565, lon: -0.4654, locations facility: Pediatric practice, city: Aix-en-Provence, state: Provence-Alpes-Côte d'Azur, zip: 13090, country: France, contacts name: Céline CASTAINGS-CARLIOZ, MD, role: CONTACT, phone: 06 20 70 02 99, phoneExt: 33, email: celine.carlioz@yahoo.fr, contacts name: Céline CASTAINGS-CARLIOZ, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 43.5283, lon: 5.44973, locations facility: Pediatric practice, city: Marseille, state: Provence-Alpes-Côte d'Azur, zip: 13008, country: France, contacts name: Hélène Bellon, MD, role: CONTACT, phone: 04 86 97 40 13, phoneExt: 33, email: h.bellon@sfr.fr, contacts name: Hélène Bellon, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 43.29551, lon: 5.38958, locations facility: Pediatric practice, city: Nice, state: Provence-Alpes-Côte d'Azur, zip: 06000, country: France, contacts name: Frédérique GASTAUD, MD, role: CONTACT, phone: 04 93 13 85 17, phoneExt: 33, email: docteurgastaud.frederique@orange.fr, contacts name: Frédérique GASTAUD, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 43.70313, lon: 7.26608, locations facility: Pediatric practice, city: Marseille, state: Provence-Alpes-Côte-d'Azur, zip: 13012, country: France, contacts name: Catherine BRUE FABRE, role: CONTACT, phone: 04 91 49 29 35, phoneExt: 33, email: catherine.brue@gmail.com, contacts name: Catherine BRUE FABRE, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 43.29551, lon: 5.38958, locations facility: Hôpital Femme Mère Enfant, Hospices civils de Lyon, city: Bron, zip: 69677, country: France, contacts name: Emilie Doye, MD, role: CONTACT, phone: 0472118890, email: emilie.doye@chu-lyon.fr, contacts name: Emilie Doye, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 45.73333, lon: 4.91667, locations facility: Pediatric practice, city: Paris, state: Île-De-France, zip: 75010, country: France, contacts name: Capucine VIGNON SAVOYE, MD, role: CONTACT, phone: 09 80 46 71 19, phoneExt: 33, email: capucinevignon@free.fr, contacts name: Capucine VIGNON SAVOYE, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 48.85341, lon: 2.3488, locations facility: Pediatric practice, city: Paris, state: Île-De-France, zip: 75011, country: France, contacts name: Isabelle FLECHTNER, MD, role: CONTACT, phone: 01 43 55 17 17, phoneExt: 33, email: drflechtner@gmail.com, contacts name: Isabelle FLECHTNER, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 48.85341, lon: 2.3488, locations facility: Pediatric practice, city: Paris, state: Île-De-France, zip: 75017, country: France, contacts name: Maxime GERARD, MD, role: CONTACT, phone: 06 37 63 83 07, phoneExt: 33, email: m.gerard.endocped@gmail.com, contacts name: Maxime GERARD, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 48.85341, lon: 2.3488, hasResults: False