protocolSection identificationModule nctId: NCT06375681, orgStudyIdInfo id: 2019-1378: R01, secondaryIdInfos id: 1R01AG076157-01, type: NIH, link: https://reporter.nih.gov/quickSearch/1R01AG076157-01, secondaryIdInfos id: A487400, type: OTHER, domain: UW Madison, briefTitle: Effectiveness of Cognitive Training in Older and Younger Adults, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2028-01, completionDateStruct date: 2028-01, studyFirstPostDateStruct date: 2024-04-19, lastUpdatePostDateStruct date: 2024-04-19, sponsorCollaboratorsModule leadSponsor name: University of Wisconsin, Madison, class: OTHER, collaborators name: National Institute on Aging (NIA), descriptionModule briefSummary: The proposed study will enroll 1600 participants to examine the effectiveness of cognitive training. Participants will be randomized into different experimental groups and can expect to participate for up to 15 hours of research over 4 to 8 weeks., conditionsModule conditions: Cognitive Change, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: FACTORIAL, interventionModelDescription: Following Pre-testing, participants randomly assigned into the full study will be further randomly assigned to a total of 9 unique experimental conditions for the full 2x2x2+1 factorial design.The full description of the study's 9 arms will be registered after data collection is completed to preserve the scientific integrity of the study., primaryPurpose: BASIC_SCIENCE, maskingInfo masking: DOUBLE, maskingDescription: All researchers that have contact with participants will be unaware of the tested hypothesis of the study.Participants will be unaware of the experimental conditions.Researchers and participants will be unaware (blinded) to the game conditions assigned to the participant, except for researchers in charge of supervising the training part of the study who will be aware what training the participant is undergoing.More information on how this was achieved will be registered after data collection is completed to preserve the scientific integrity of the study., whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 1600, type: ESTIMATED, armsInterventionsModule interventions name: Visual and / or Auditory Cognitive Tasks (1), interventions name: Visual and / or Auditory Cognitive Tasks (2), outcomesModule primaryOutcomes measure: Change in the difference between the proportion of hits minus false alarms for a given level of the N-back task, primaryOutcomes measure: Change in the proportion of correctly reported sequences in the Corsi Complex task, primaryOutcomes measure: Change in the proportion of correctly reported number and letter sets in the Letter-Number task, primaryOutcomes measure: Change in the difference of response time and accuracy in switch trials minus non-switch trials in the Task Switching Task, primaryOutcomes measure: Change in the difference of response time in (i) switch trials minus non-switch trials and (ii) congruent minus incongruent trials in the Flanker Task, primaryOutcomes measure: Change in the proportion of correctly identified targets in the mixed condition of the Cancellation task, primaryOutcomes measure: Change in the proportion of correct responses on the Useful Field of View (UFOV) Task, primaryOutcomes measure: Change in the proportion of correct responses on the Multiple Object Tracking (MOT) Task, primaryOutcomes measure: Change in the response time and percentage of correct responses in the Mental Rotation Task, primaryOutcomes measure: Change in the percentage of correct responses in the Paper Folding task, primaryOutcomes measure: Change in the sum of correctly solved items in Raven's Advanced Progressive Matrices task, primaryOutcomes measure: Change in the sum of correctly solved items in the UC Matrix Reasoning task, primaryOutcomes measure: Change in the percentage of accuracy in the Shipley Institute of Living Scale, primaryOutcomes measure: Change in the percentage of accuracy in the Mill-Hill Vocabulary Scale, secondaryOutcomes measure: Big-5-Inventory 10-item version (BFI-10) Score, secondaryOutcomes measure: Behavioral Inhibition/Activation System (BIS/BAS) Score, secondaryOutcomes measure: Grit and Conscientiousness Score, secondaryOutcomes measure: Meta-Cognition Score, secondaryOutcomes measure: Theories of Intelligence - Mindset (Fixed vs Growth) Score, secondaryOutcomes measure: Schutte self-report emotional intelligence test (SSEIT) Score, secondaryOutcomes measure: Work and Family Orientation (WOFO) Score, secondaryOutcomes measure: Brief Pittsburgh Sleep Quality Index (B-PSQI) Score, secondaryOutcomes measure: Participant Experience Measure 1, secondaryOutcomes measure: Participant Experience Measure 2, secondaryOutcomes measure: Participant Experience Measure 3, secondaryOutcomes measure: Participant Experience Measure 4, secondaryOutcomes measure: Participant Experience Measure 5, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 85 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of California, Riverside, city: Riverside, state: California, zip: 92521, country: United States, contacts name: Aaron Seitz, PhD, role: CONTACT, phone: 951-827-6422, email: aseitz@ucr.edu, geoPoint lat: 33.95335, lon: -117.39616, locations facility: Northeastern University, city: Boston, state: Massachusetts, zip: 02115, country: United States, contacts name: Susanne Jaeggi, PhD, role: CONTACT, phone: 617-373-3653, email: s.jaeggi@northeastern.edu, geoPoint lat: 42.35843, lon: -71.05977, locations facility: University of Wisconsin - Madison, city: Madison, state: Wisconsin, zip: 53706, country: United States, contacts name: C. Shawn Green, PhD, role: CONTACT, phone: 608-263-4868, email: cshawn.green@wisc.edu, geoPoint lat: 43.07305, lon: -89.40123, hasResults: False