hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06346652, orgStudyIdInfo id: REC-UOL-216-03-2024, briefTitle: Effects of Core Strengthening and PNF Pattern on Static Balance and Plantar Pressure in Chronic Stroke Patients, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-10, primaryCompletionDateStruct date: 2024-04-22, completionDateStruct date: 2024-04-30, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: University of Lahore, class: OTHER, descriptionModule briefSummary: Stroke is a neurological disease characterized by neurological deficits caused by insufficiency of blood supply to brain. Disruption of blood supply to brain can be due to blockage of blood supply (ischemic) or leakage of blood in brain due to rupture of blood vessel (hemorrhagic). 90.5% of global occurrence of stroke was subjected to modifiable risk factors according to Global Burden of Disease study.This study aims to compare the effects of core strengthening and proprioceptive neuromuscular facilitation on static standing balance and plantar pressure in chronic stroke patients., conditionsModule conditions: Chronic Stroke, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 73, type: ESTIMATED, armsInterventionsModule interventions name: Routine Physical Therapy, interventions name: Routine Physical Therapy+ PNF and Core Stregthening, outcomesModule primaryOutcomes measure: Static Standing Balance, secondaryOutcomes measure: Plantar Pressure, eligibilityModule sex: ALL, minimumAge: 45 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: The University of Lahore Teaching Hospital, status: RECRUITING, city: Lahore, zip: 54000, country: Pakistan, contacts name: Safa Saleem, MSPTN, role: CONTACT, phone: 03354028864, email: safah.saleem@gmail.com, contacts name: Sameed Liaqat, MPhil, role: CONTACT, phone: 03249004200, email: samiliaqat3@gmail.com, geoPoint lat: 31.558, lon: 74.35071, hasResults: False
protocolSection identificationModule nctId: NCT06346626, orgStudyIdInfo id: 2WIN-S2024, briefTitle: To Evaluate the Consistency and Repeatability of Portable Automatic Optometry 2-WINS for Cycloplegic Optometry in Adolescents and Children, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-06-01, completionDateStruct date: 2024-06-01, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: He Eye Hospital, class: OTHER, descriptionModule briefSummary: Myopia, also known as short-sightedness or near-sightedness, is a prevalent condition that typically emerges during childhood and early adulthood. It occurs when the eye elongates excessively, causing images of distant objects to focus in front of the retina, leading to blurred distance vision. The number of people with myopia is increasing every year, reaching half of the world's population by 2050. The global potential productivity loss due to uncorrected refractive errors was $244 billion in 2015. Due to the strong association between high myopia and pathological changes in the choroid, retina, and sclera, leading to irreversible vision loss, and the fact that correcting the refractive error does not halt the progression of pathology, the prevention of myopia, especially high myopia, has emerged as a crucial international public health concern. In ocular examinations of children under noncycloplegic conditions, the influence of accommodation cannot be disregarded.Cycloplegic refraction is widely regarded as the gold standard in epidemiological assessment of refractive errors in pediatric populations. Moreover, due to children's decreased cooperation and unreliable responses, subjective refraction tests are less valued, and objective tests under cycloplegia are preferred. The portable vision screener 2WIN-S is a binocular tool that detects various ocular abnormalities and measures the refraction of both eyes. Along with measuring phorias/tropias in prismatic diopters and objective refraction in the range of -15D to +15D, 2WIN-S also captures additional features.This study employed the cycloplegic condition to measurements using 2WIN-S, ARK-1 and subjective testing, we wanted to test the reliability and accuracy of 2WIN-S., conditionsModule conditions: Optometry, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 150, type: ESTIMATED, outcomesModule primaryOutcomes measure: The optometric result (2WIN-S), secondaryOutcomes measure: The optometric result(ARK-1), secondaryOutcomes measure: The optometric result(subjective refraction), secondaryOutcomes measure: The optometric result, eligibilityModule sex: ALL, minimumAge: 3 Years, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06346613, orgStudyIdInfo id: B2024-076R, briefTitle: Prevalence and Affecting Factors of Sleep and Circadian Rhythm Disorders in ICU, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-07, primaryCompletionDateStruct date: 2025-01-31, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Shanghai Zhongshan Hospital, class: OTHER, descriptionModule briefSummary: Most ICU patients experience sleep and circadian disruption (SCD), which causes a profound negative impact on patients, such as prolonged mechanical ventilation, glucose intolerance, and the occurrence of delirium. In order to better promote the alignment of circadian rhythm in ICU patients, this project will explore the prevalence of SCD and a series of influencing factors contributing to SCD in ICU patients, to help construct targeted intervention programs in the future., conditionsModule conditions: Sleep Deprivation, conditions: Circadian Rhythm Disorders, conditions: Critical Illness, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 56, type: ESTIMATED, outcomesModule primaryOutcomes measure: Rhythmicity of melatonin levels., secondaryOutcomes measure: Overnight sleep duration, secondaryOutcomes measure: Wake after sleep onset(WASO), secondaryOutcomes measure: Overnight Rapid Eye Movement (REM) proportion, secondaryOutcomes measure: Overnight non-rapid eye movement stage 1 (NREM1) proportion, secondaryOutcomes measure: Overnight non-rapid eye movement stage 2 (NREM2) proportion, secondaryOutcomes measure: Overnight non-rapid eye movement stage 3 (NREM3) proportion, secondaryOutcomes measure: Sleep period time ratio (sleep continuity), secondaryOutcomes measure: Subject sleep quality, secondaryOutcomes measure: Activity counts, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: 180 Fenglin Road, status: RECRUITING, city: Shanghai, zip: 20032, country: China, contacts name: Shining Cai, MSc, role: CONTACT, phone: 86-021-64041990, phoneExt: 2724, email: cai.shining@zs-hospital.sh.cn, contacts name: Yuxia Zhang, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 31.22222, lon: 121.45806, hasResults: False
protocolSection identificationModule nctId: NCT06346587, orgStudyIdInfo id: VRU751-C001, briefTitle: [Trial of device that is not approved or cleared by the U.S. FDA], statusModule overallStatus: WITHHELD, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: [Redacted], hasResults: False
protocolSection identificationModule nctId: NCT06346561, orgStudyIdInfo id: Soh-Med-24-02-10MS, briefTitle: The Efficacy of Dexmedetomidine Versus Labetalol In Providing Controlled Hypotension In Dacryocystorhinostomy SurgeryA Comparative Randomized Prospective Study, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-30, primaryCompletionDateStruct date: 2024-08-30, completionDateStruct date: 2024-08-30, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Sohag University, class: OTHER, descriptionModule briefSummary: The most important symptoms of nasolacrimal duct obstruction are excessive tearing and mucoid discharge.The proposed treatment in this regard is dacryocystorhinostomy (DCR) surgery. Therefore, hemostasis is of great significance in performing DCR surgery. In this regard, the reduction of controlled hypotension and the control of hemodynamic responses of the body to stress effectively reduce the bleeding volume during surgery.Hence, there is no enough studies about controlled hypotension in DCR we decided to perform such a comparison between the effect of dexmedetomidine and labetalol in providing controlled hypotension during DCR surgery., conditionsModule conditions: Nasolacrimal Duct Obstruction, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Dexmedetomidine, interventions name: Labetalol, outcomesModule primaryOutcomes measure: Assess non invasive blood pressure during DCR surgery To compare between the effect of dexmedetomidine and labetalol in providing controlled hypotension., secondaryOutcomes measure: Effectiveness of dexamedetomidine for prolongation of postoperative analgesia., eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Sohag University hospitals, status: RECRUITING, city: Sohag, country: Egypt, contacts name: Magdy M Amin, Professor, role: CONTACT, geoPoint lat: 26.55695, lon: 31.69478, hasResults: False
protocolSection identificationModule nctId: NCT06346548, orgStudyIdInfo id: VF-ES-DIG, briefTitle: Study on the Chromatic Perception of Digital Systems in Aesthetic Field, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09-27, primaryCompletionDateStruct date: 2025-06-15, completionDateStruct date: 2025-06-15, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Paolone Gaetano, class: OTHER, descriptionModule briefSummary: The study under consideration aims to evaluate differences in chromatic perception among three distinct color acquisition methodologies. Specifically, recruited patients will undergo testing with three different color detection systems, including two intraoral photography methodologies and one digital intra oral scanning. All procedures conducted are part of normal clinical practice., conditionsModule conditions: Color Detection of Upper Central Incisors, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: OTHER, enrollmentInfo count: 78, type: ESTIMATED, armsInterventionsModule interventions name: oral photography, outcomesModule primaryOutcomes measure: Comparison of chromatic values of the upper central incisors, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: IRCCS San Raffaele, city: Milano, zip: 20132, country: Italy, contacts name: Federico Vannini, role: CONTACT, phone: +393450764177, email: f.vannini@studenti.unisr.it, geoPoint lat: 45.46427, lon: 9.18951, hasResults: False
protocolSection identificationModule nctId: NCT06346522, orgStudyIdInfo id: FMASU R37/2024, briefTitle: Gabapentin Versus Trospium Chloride for Prevention of a Catheter-related Bladder Discomfort Inside the ICU, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-24, primaryCompletionDateStruct date: 2024-07, completionDateStruct date: 2024-08, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Ain Shams University, class: OTHER, descriptionModule briefSummary: Catheter-related bladder discomfort (CRBD) is a frequent complaint after urinary bladder catheterization which is commonly done in the perioperative period. CRBD shows similar symptoms to overactive bladder (OAB); so, drugs used for the management of OAB could influence symptoms of CRBD. Trospium chloride and gabapentin are effective in managing patient with OAB even the resistant cases. We will evaluate and compare the efficacy of both oral trospium and gabapentin on prevention of CRBD in the postoperative period in the ICU in in patients undergoing spinal surgery and requiring intraoperative catheterization of the urinary bladder., conditionsModule conditions: Catheter-related Bladder Discomfort (CRBD), designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: A prospective, randomized, comparative, clinical trial study, primaryPurpose: PREVENTION, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Gabapentin (Gaptin ®) 400mg oral capsule once, interventions name: Trospium chloride slow release (Trospikan ® SR) 60mg oral capsule, outcomesModule primaryOutcomes measure: The incidence (yes/no) and severity of catheter-related bladder discomfort (CRBD) in 1,2,6,12,24 hours after the study drugs intake, secondaryOutcomes measure: Total fentanyl requirements in micrograms (µg), secondaryOutcomes measure: Numerical Pain Rating Scale (NPRS) (0-10), secondaryOutcomes measure: Side effects of the study drugs, secondaryOutcomes measure: Ramsay sedation score, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Ain Shams University-Faculty of Medicine, status: RECRUITING, city: Cairo, country: Egypt, contacts name: Ahmed M Mohamed, MD, role: CONTACT, phone: 002 01121318459, email: drahmed.mostafa.mohamed@med.asu.edu.eg, contacts name: Wessam Z Selima, MD, role: CONTACT, phone: 002 01001958858, email: w.z.selima@med.asu.edu.eg, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06346509, orgStudyIdInfo id: PORT-77-101, briefTitle: Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study of PORT-77 Administered to Healthy Adult Participants, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-08, primaryCompletionDateStruct date: 2024-12-23, completionDateStruct date: 2024-12-23, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Portal Therapeutics, Inc., class: INDUSTRY, descriptionModule briefSummary: A First-in-Human 2-part, randomized, double-blind, placebo-controlled, single ascending dose, multiple ascending dose, and food effect, investigation of the administration of PORT-77 in healthy adult participants., conditionsModule conditions: Healthy Adult Participants, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: RANDOMIZED, interventionModel: SEQUENTIAL, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, enrollmentInfo count: 108, type: ESTIMATED, armsInterventionsModule interventions name: PORT-77, interventions name: Placebo, outcomesModule primaryOutcomes measure: Number of incidence and severity of adverse events (AEs) as a measure of safety and tolerability of PORT-77 (Part I), primaryOutcomes measure: Number of incidence and severity of AEs as a measure of safety and tolerability of PORT-77 (Part II), secondaryOutcomes measure: Plasma concentration of a single-dose of PORT-77 (Part I), secondaryOutcomes measure: Plasma concentration of the steady-state of PORT-77 (Part II), secondaryOutcomes measure: Plasma concentration of PORT-77 by effect of a standardized high-fat/high-calorie meal (Part I), secondaryOutcomes measure: Evaluate effects of single doses of PORT-77 on ECG parameters (Part I), secondaryOutcomes measure: Evaluate effects of single doses of PORT-77 on ECG parameters (Part II), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule locations facility: Celerion, city: Tempe, state: Arizona, zip: 85283, country: United States, contacts role: CONTACT, email: mara.baier@celerion.com, contacts name: Mara Baier, DO, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 33.41477, lon: -111.90931, hasResults: False
protocolSection identificationModule nctId: NCT06346496, orgStudyIdInfo id: H23133, briefTitle: Young People Aged 18-25 With Depression or Anxiety Mood Participate in an LLM-based Digital Dialogue Intervention Study, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-11-20, primaryCompletionDateStruct date: 2023-12-18, completionDateStruct date: 2024-01-15, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Institute of Psychology, Chinese Academy of Sciences, class: OTHER, descriptionModule briefSummary: This study is a 28-day randomized controlled trial (RCT). Residents were randomly assigned to an intervention group or a waiting group according to the order in which they were successfully contacted by the staff, and each user was asked to engage in a total of 28 days of dialog intervention with the Douyin companion bot and complete three psychological questionnaires (on Days 1, 14, and 28); however, the intervention group began to receive the dialog intervention after completing the first questionnaire, and the waiting group began to receive the dialog intervention after completing the third questionnaire. During the first four weeks, the waiting group was treated as a blank control. The two groups of subjects completed the three questionnaires at exactly the same point in time. Each user's depression, anxiety, and positive and negative emotions were measured using the Patient Health Questionnaire (PHQ-9), the Generalized Anxiety Disorder Scale (GAD-7) and the Positive and Negative Affect Schedule (PANAS), respectively., conditionsModule conditions: LLM-based AI Dialogue Bot, conditions: Depression, conditions: Anxiety, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 657, type: ACTUAL, armsInterventionsModule interventions name: Douyin Xinqing AI dialog bot, interventions name: Douyin Xinqing AI dialog bot for delayed intervention, outcomesModule primaryOutcomes measure: Depression, primaryOutcomes measure: Anxiety, primaryOutcomes measure: Positive and negative moods, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 25 Years, stdAges: ADULT, contactsLocationsModule locations facility: Institute of Psychology, Chinese Academy of Sciences, city: Beijing, state: Beijing, country: China, geoPoint lat: 39.9075, lon: 116.39723, hasResults: False
protocolSection identificationModule nctId: NCT06346483, orgStudyIdInfo id: STU00218929, briefTitle: Ureteroscopy With High-powered Holmium:Yag Laser Lithotripsy With and Moses On or Moses Off, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-06-09, primaryCompletionDateStruct date: 2024-06-09, completionDateStruct date: 2025-06-09, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Northwestern University, class: OTHER, collaborators name: Ohio State University, descriptionModule briefSummary: The purpose of this study is to compare Moses 2.0 pulse modulation technology and the standard high powered Holmium Laser lithotripsy and how it will affect time in the operating room, time using the laser, laser energy, and stone free rates.Currently Moses 2.0 laser technology is FDA approved and currently used in practice since 2021. No study to this date has compared Moses 2.0 without pulse modulation laser technology to Moses 2.0 with pulse modulation laser technology.The study will be including kidney and ureteral stones (a kidney stone located in the tube between the kidney and the bladder) that are 6mm and greater, but less than 20 mm in size undergoing ureteroscopic treatment. High powered lasers are used for "dusting". Dusting is when a laser is used to break a stone down into tiny fragments that are able to pass through the urine., conditionsModule conditions: Kidney Stone, conditions: Ureteral Stone, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 150, type: ESTIMATED, armsInterventionsModule interventions name: Dusting, outcomesModule primaryOutcomes measure: Operative time, primaryOutcomes measure: Stone Free Rate, secondaryOutcomes measure: Lasing time, secondaryOutcomes measure: Total laser energy (kJ), secondaryOutcomes measure: Detection of postoperative strictures, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 90 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Northwestern Medicine, status: RECRUITING, city: Chicago, state: Illinois, zip: 60611, country: United States, contacts name: Alyssa McDonald, role: CONTACT, geoPoint lat: 41.85003, lon: -87.65005, hasResults: False