hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06307171, orgStudyIdInfo id: 2023-11, briefTitle: Human Leishmaniasis: Antigen Recognition Pattern and Study of New Potential Biomarkers, acronym: LeishmARPs, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-05-22, primaryCompletionDateStruct date: 2026-11, completionDateStruct date: 2026-11, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: IRCCS Sacro Cuore Don Calabria di Negrar, class: OTHER, descriptionModule briefSummary: This is an exploratory experimental multicentre study on archived serum samples and on prospectively collected serum samples and blood samples.General objectives of the study are: to identify specific biomarkers in order to develop more accurate serological tests for the screening of Leishmania infections that does not present cross-reaction with other infectious diseases; to unveil the Antigen Recognition Patterns (ARPs) of Leishmania infection in humans; to verify whether the ARPs and the new biomarkers are common to different Leishmania infantum strains isolated in Italy as well as in other part of the World and to different strains of L. donovani isolated in Sudan as well as in other part of the World and discard any possible cross reaction with other infectious diseases such as Chagas, TB, leprosy or malaria., conditionsModule conditions: Leishmaniasis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: SINGLE_GROUP, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 170, type: ESTIMATED, armsInterventionsModule interventions name: In-house Western blot, specific for Leishmania, outcomesModule primaryOutcomes measure: Biomarkers from Leishmania spp, secondaryOutcomes measure: ARPs in different Leishmania infantum and L. donovani strains, secondaryOutcomes measure: Cross reaction, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: IRCCS Sacro Cuore Don Calabria hospital, status: RECRUITING, city: Negrar, state: Verona, zip: 37024, country: Italy, contacts name: Silvia Longoni, role: CONTACT, phone: +390456013111, email: silvia.longoni@sacrocuore.it, contacts name: Silvia Longoni, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 45.52918, lon: 10.93899, hasResults: False
protocolSection identificationModule nctId: NCT06307158, orgStudyIdInfo id: CT2024-ZJU-OBS1, briefTitle: Influence of Intraoperative Blood Salvage and Autotransfusion on Tumor Recurrence After Deceased Donor Liver Transplantation, statusModule overallStatus: COMPLETED, startDateStruct date: 2015-01-01, primaryCompletionDateStruct date: 2020-12-31, completionDateStruct date: 2021-12-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Zhejiang University, class: OTHER, collaborators name: Shulan (Hangzhou) Hospital, descriptionModule briefSummary: The practice of intraoperative blood salvage and autotransfusion (IBSA) during deceased donor liver transplantation (DDLT) for hepatocellular carcinoma (HCC) can potentially reduce the need for allogeneic blood transfusion. However, implementing IBSA remains debatable due to concerns about its possible detrimental effects on oncologic recurrence. Hence, a nationwide multi-center study was conducted to investigate further the association between IBSA and post-transplant HCC recurrence, including a stratified subgroup analysis., conditionsModule conditions: Liver Transplant; Complications, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 998, type: ACTUAL, armsInterventionsModule, outcomesModule primaryOutcomes measure: Postoperative recurrence of liver cancer, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06307145, orgStudyIdInfo id: K-NHIS-HIP, briefTitle: Korea Hip Replacement Surgery Registry, statusModule overallStatus: COMPLETED, startDateStruct date: 2003-01-01, primaryCompletionDateStruct date: 2020-12-31, completionDateStruct date: 2020-12-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Samsung Medical Center, class: OTHER, descriptionModule briefSummary: This cohort study obtained data from the Korean National Health Insurance Service (K-NHIS) database. For the hip replacement registry, we included all adult patients older than 19 who received total or hemiarthroplasty surgery between January 1, 2003, and December 31, 2019. Using this registry, we compared efficacy and safety by type of head or liner., conditionsModule conditions: Hip Replacement Surgery, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 124556, type: ACTUAL, outcomesModule primaryOutcomes measure: Cancer, eligibilityModule sex: ALL, minimumAge: 19 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06307132, orgStudyIdInfo id: SAHoWMU-CR2024-03-106, briefTitle: Drug Metabolism, Excretion, and Human Body Composition of Aximus Capsules, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-01-31, primaryCompletionDateStruct date: 2024-06-30, completionDateStruct date: 2024-08-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Second Affiliated Hospital of Wenzhou Medical University, class: OTHER, descriptionModule briefSummary: This project will be based on the bioequivalence test of Aximus capsules, measuring the body composition indicators of healthy subjects before and after medication, and collecting urine samples from subjects at different time periods after medication, measuring urine drug concentration, calculating urine excretion, analyzing the individualized differences in metabolism and excretion of Aximus capsules under different health states of human components, and providing guidance for clinical precision medication., conditionsModule conditions: Bioequivalence Trial, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 26, type: ESTIMATED, armsInterventionsModule interventions name: Aximus capsules（test）, interventions name: Aximus capsules（reference）, outcomesModule primaryOutcomes measure: Excretion volume, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule locations facility: The Second Affiliated Hospital of WMU Phase l Clinical Trial Unit /Center Of Bioequivalence Study, city: Wenzhou, country: China, geoPoint lat: 27.99942, lon: 120.66682, hasResults: False
protocolSection identificationModule nctId: NCT06307119, orgStudyIdInfo id: 2020-01, briefTitle: Model of Human Occupation-Based Intervention on Premenstrual Syndrome Symptoms, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-03-01, primaryCompletionDateStruct date: 2024-03-01, completionDateStruct date: 2024-03-02, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Saglik Bilimleri Universitesi, class: OTHER, descriptionModule briefSummary: This study was conducted to examine the effect of two different occupational therapy interventions on premenstrual syndrome symptoms in university students. This study was designed according to the CONSORT statement, which provides a standard method for randomised controlled trial (RCT) design. The study was approved by the Local Ethics Committee. Written informed consent was obtained from all participants before the study., conditionsModule conditions: Premenstrual Syndrome, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 95, type: ACTUAL, armsInterventionsModule interventions name: Occupational Therapy and Relaxation Group, interventions name: Relaxation Group, outcomesModule primaryOutcomes measure: Occupational Self-Assessment, secondaryOutcomes measure: The Model of Human Occupation Screening Tool (MOHOST), otherOutcomes measure: Premenstrual Symptom Screening Tool, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Health Sciences Turkey, city: Ankara, country: Turkey, geoPoint lat: 39.91987, lon: 32.85427, hasResults: False
protocolSection identificationModule nctId: NCT06307106, orgStudyIdInfo id: #40\14-Jan-2024, briefTitle: Various Strategies to Reduce Acute Post Hemorrhoidectomy Pain: A Comparative Study, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-01-14, primaryCompletionDateStruct date: 2024-07-14, completionDateStruct date: 2024-07-14, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Zagazig University, class: OTHER_GOV, descriptionModule briefSummary: Since post hemorrhoidectomy pain is a severe and common post operative symptom so there is a need to find a suitable method for reducing this pain, up to our knowledge, this the first study in ZUH to compare between ketrolac, light Marcaine, corticosteroids and diclofenac sodium injection at surgical site for relieve of post operative pain. This is a randomizes comparative prospective clinical trial., conditionsModule conditions: Acute Post Operative Pain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 120, type: ACTUAL, armsInterventionsModule interventions name: ketorolac and light marcaine, interventions name: light marcaine, interventions name: Corticosteroids injection, interventions name: Diclofenac Sodium Gel, outcomesModule primaryOutcomes measure: age, primaryOutcomes measure: sex, primaryOutcomes measure: number of hemorrhoids, primaryOutcomes measure: degree of hemorroids, primaryOutcomes measure: post operative pain, primaryOutcomes measure: ambulation, primaryOutcomes measure: return to work, primaryOutcomes measure: patient satisfaction, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Zagazig University Hospitals, city: Zagazig, zip: 44519, country: Egypt, geoPoint lat: 30.58768, lon: 31.502, hasResults: False
protocolSection identificationModule nctId: NCT06307080, orgStudyIdInfo id: IIT2023-064, briefTitle: Clinical Study of Multi-mode Thermal Ablation for the Treatment of Pancreatic Cancer With Liver Metastasis, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-10-08, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, class: OTHER, descriptionModule briefSummary: 1. Clinical evaluation of multimodal ablation system for pancreatic cancer with hepatic metastatic malignancies.2. Construction of a combined treatment system of multimodal ablation therapy combined with immunotherapy and chemotherapy.3. Transformation and clinical application of multimodal ablation system for pancreatic cancer with hepatic metastatic malignancies., conditionsModule conditions: Pancreatic Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 12, type: ESTIMATED, armsInterventionsModule interventions name: Multi-mode thermal ablation device, interventions name: Intravenous anti-PD-1 and chemotherapy, outcomesModule primaryOutcomes measure: Safety and efficacy assessment, secondaryOutcomes measure: Survival benefit, otherOutcomes measure: The application of medical-mechanical combination therapy mode, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Shanghai General Hospital, status: RECRUITING, city: Shanghai, state: Shanghai, zip: 200040, country: China, contacts name: Jiang Long, MD, role: CONTACT, phone: +86 18017317460, email: jiang.long@shgh.cn, geoPoint lat: 31.22222, lon: 121.45806, hasResults: False
protocolSection identificationModule nctId: NCT06307067, orgStudyIdInfo id: URINDO, briefTitle: Improving Care for Uncomplicated URinary Tract Infection-associated Symptoms in Primary Healthcare Settings in INDOnesia, acronym: URINDO, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-04, primaryCompletionDateStruct date: 2024-11-04, completionDateStruct date: 2025-06-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Erasmus Medical Center, class: OTHER, collaborators name: Saiful Anwar Hospital, collaborators name: Brawijaya University, Malang, Indonesia, collaborators name: Diponegoro University/Diponegoro National Hospital, Semarang, Indonesia, collaborators name: Bali Mandara Hospital, Denpasar, Bali, Indonesia, descriptionModule briefSummary: In the present study, we aim to analyze the impact of the introduction of a urinary dipstick test for patients presenting with uncomplicated UTI-associated symptoms on antibiotic prescription in primary health care in Indonesia. In addition, the knowledge of HCW regarding antibiotics and prudent use of antibiotics in the community setting will be investigated.Specific aims of the study:1. To analyze the quality of antibiotic prescriptions for uncomplicated UTI in the primary health care settings in Indonesia, before introduction of urinary dipstick testing compared to after introduction of urinary dipstick testing.2. To analyze the knowledge level of healthcare workers on uncomplicated UTI and prudent antibiotic use in primary health care settings in Indonesia., conditionsModule conditions: Urinary Tract Infections, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 300, type: ESTIMATED, armsInterventionsModule interventions name: Urine dipstick, outcomesModule primaryOutcomes measure: appropriateness of prescriptions for uncomplicated UTI-associated symptoms in the primary health care settings in Indonesia, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Erasmus Medical Center, city: Rotterdam, state: Zuid-Holland, zip: 3015 GD, country: Netherlands, geoPoint lat: 51.9225, lon: 4.47917, hasResults: False
protocolSection identificationModule nctId: NCT06307054, orgStudyIdInfo id: SHSY-CAR-NK-AML01, briefTitle: CLL-1 CAR-NK Cells for Relapsed/Refractory AML, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-15, primaryCompletionDateStruct date: 2026-03-15, completionDateStruct date: 2027-03-15, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, class: OTHER, descriptionModule briefSummary: This study is a single-arm, open-label, dose-escalation clinical trial aimed at exploring the safety, tolerability, and pharmacokinetic characteristics of the CLL-1 CAR NK cells, as well as providing preliminary observations on its efficacy in subjects with relapsed/refractory acute myeloid leukemia., conditionsModule conditions: Relapsed Adult AML, conditions: Refractory AML, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 24, type: ESTIMATED, armsInterventionsModule interventions name: anti-CLL-1 CAR NK cells, outcomesModule primaryOutcomes measure: AE, primaryOutcomes measure: DLT, secondaryOutcomes measure: Peak Plasma Concentration (Cmax), secondaryOutcomes measure: PD, secondaryOutcomes measure: Complete response, secondaryOutcomes measure: Duration of response (DOR), secondaryOutcomes measure: Progression-free survival (PFS), secondaryOutcomes measure: Overall survival (OS), secondaryOutcomes measure: Number of participants with treatment-related AEs as assessed by CTCAE v5.0, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Shanghai General Hospital, status: RECRUITING, city: Shanghai, state: Shanghai, zip: 200080, country: China, contacts name: Xianmin Song, MD, role: CONTACT, phone: +86 21 63240090, phoneExt: 3175, email: shongxm@139.com, contacts name: Xianmin Song, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 31.22222, lon: 121.45806, hasResults: False
protocolSection identificationModule nctId: NCT06307041, orgStudyIdInfo id: OSATAGUN, briefTitle: Effects of 0.2% Hyaluronic Acid Gel-Impregnated Dental Flosses on Clinical Gingival Parameters, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-04-03, primaryCompletionDateStruct date: 2023-07-07, completionDateStruct date: 2023-08-11, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Özlem SARAÇ ATAGÜN, class: OTHER, descriptionModule briefSummary: This study aimed to evaluate the effects of 0.2% HA-impregnated dental flosses on the clinical periodontal parameters of patients with gingivitis., conditionsModule conditions: Gingivitis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: SEQUENTIAL, interventionModelDescription: single-center, single-blinded, split-mouth, randomized clinical trial, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: SINGLE, maskingDescription: The investigator who performed the measurements was blinded to which side of patients was the test group, whoMasked: INVESTIGATOR, enrollmentInfo count: 30, type: ACTUAL, armsInterventionsModule interventions name: Dental floss+Gengigel, interventions name: Dental Floss, outcomesModule primaryOutcomes measure: Clinical Periodontal Parameter-Gingival Index (GI), primaryOutcomes measure: Clinical Periodontal Parameter-Papillary Bleeding Index (PBI), primaryOutcomes measure: Clinical Periodontal Parameter-Plaque Index(PI), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 47 Years, stdAges: ADULT, contactsLocationsModule locations facility: Sağlık Bilimleri Üniversitesi Gülhane Diş Hekimliği Fakültesi, city: Ankara, zip: 06010, country: Turkey, geoPoint lat: 39.91987, lon: 32.85427, hasResults: False
protocolSection identificationModule nctId: NCT06307028, orgStudyIdInfo id: Pro2023002116, secondaryIdInfos id: K01DA050496, type: NIH, link: https://reporter.nih.gov/quickSearch/K01DA050496, briefTitle: Sistas Informing Sistas on Topics About AIDS and Prevention (SISTA-P), acronym: SISTA-P, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-08, primaryCompletionDateStruct date: 2024-07-01, completionDateStruct date: 2024-08-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Rutgers, The State University of New Jersey, class: OTHER, collaborators name: National Institutes of Health (NIH), collaborators name: National Institute on Drug Abuse (NIDA), descriptionModule briefSummary: In this project, the investigators will provide a new HIV prevention training and empowerment sessions to Black women in Washington D.C. who are at high risk for getting HIV. This training is tailored to the experience of Black women and seeks to reduce the high HIV transmission rates in the Black community., conditionsModule conditions: Health Behavior, Risky, conditions: Health Knowledge, Attitudes, Practice, conditions: Health-Related Behavior, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: SISTA-P Intervention, outcomesModule primaryOutcomes measure: Feasibility of the Intervention Scale, primaryOutcomes measure: Acceptability of the Intervention Scale, primaryOutcomes measure: Appropriateness of the Intervention Scale, secondaryOutcomes measure: Recruitment, secondaryOutcomes measure: Intervention Fidelity- participant characteristics, secondaryOutcomes measure: Intervention Fidelity, secondaryOutcomes measure: Acceptability of the intervention delivery, secondaryOutcomes measure: Participant Enrollment, secondaryOutcomes measure: Participant Retention, secondaryOutcomes measure: Feasibility of delivering 6 sessions in 6 weeks, secondaryOutcomes measure: Visual confirmation of self-reported PrEP uptake, secondaryOutcomes measure: Post-Intervention Follow-up, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The Women's Collective, status: ACTIVE_NOT_RECRUITING, city: Washington, state: District of Columbia, zip: 20002, country: United States, geoPoint lat: 38.89511, lon: -77.03637, locations facility: Rutgers University, status: RECRUITING, city: New Brunswick, state: New Jersey, zip: 08854, country: United States, contacts name: Shawnika Hull, PhD, role: CONTACT, phone: 520-661-3300, email: shawnika.hull@rutgers.edu, contacts name: Shawnika Hull, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 40.48622, lon: -74.45182, hasResults: False