hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06293274, orgStudyIdInfo id: sdilek5, briefTitle: The Importance of Discharge Education for Mommy Blues, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2024-03-30, completionDateStruct date: 2024-05-30, studyFirstPostDateStruct date: 2024-03-05, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Kocaeli University, class: OTHER, descriptionModule briefSummary: The study will be conducted with participants who will give birth at Farabi Training and Research Hospital in Darıca District, Kocaeli Province.The sample size of the study was calculated using the G\*Power 3.1.9.2 program, and the effect size of the Edinburgh Postnatal Depression Scale (EPDS) score in the Sun et al. (2021) study was considered in the effect size calculation. In the relevant article, the effect size is reported as effect size: 0.47. In our planned research, the minimum number of individuals to be sampled was calculated using G\*Power 3.1.9.2 with effect size: 0.47 α= 0.05, power: 0.80, and the sample size was set at a minimum of 57 participants in each group. In anticipation of possible data loss, the study will be completed with a total of 140 participants, including 70 cases and 70 routine discharge training groups. This research aims to determine the effect of discharge training on maternal blues and postpartum depression on the levels of maternal blues and postpartum depression during postpartum follow-up., conditionsModule conditions: Postpartum Sadness, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 140, type: ESTIMATED, armsInterventionsModule interventions name: Discharge training, outcomesModule primaryOutcomes measure: Motherhood Sadness Scale, primaryOutcomes measure: Edinburgh Postnatal Depression Scale - EPDS, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule locations facility: Kocaeli University, status: RECRUITING, city: Kocaeli, zip: 41380, country: Turkey, contacts name: Sena Dilek Aksoy, Ph.D., role: CONTACT, phone: +902623034739, email: sena.dilek@kocaeli.edu.tr, contacts name: Resmiye Ozdilek, Ph.D, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 39.62497, lon: 27.51145, hasResults: False
protocolSection identificationModule nctId: NCT06293248, orgStudyIdInfo id: 77979112, briefTitle: Music Application in Patients Undergoing Percutaneous Coronary Intervention, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-07-10, primaryCompletionDateStruct date: 2023-12-31, completionDateStruct date: 2024-05-31, studyFirstPostDateStruct date: 2024-03-05, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Kocaeli University, class: OTHER, descriptionModule briefSummary: This study was planned to examine the effect of music application on recovery in patients undergoing coronary angiography (CAG) and to obtain the opinions of patients and nurses about music.This study was conducted to examine the effect of music application on recovery in patients undergoing CAG and to obtain the opinions of patients and nurses about music.The study was planned as a pre-test, post-test design, single-center, randomized controlled experimental study. The study is planned to be conducted in the CAG unit of a university hospital between July 2023 and December 2023, the study sample will be composed of a total of 210 individuals, 105 in each group (music applied group before and after the procedure = 105, control group = 105) To collect data in the study, the "Patient Information Form", Vital Signs Evaluation Form", "Numerical Rating Scale", State-Trait Anxiety Inventory, "Perianesthesia Comfort Scale" and "Patient Satisfaction Survey on Nursing Care Quality" were used., conditionsModule conditions: Healthy, conditions: Nurse's Role, conditions: Patient Satisfaction, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: SINGLE, maskingDescription: Single (Participant), whoMasked: PARTICIPANT, enrollmentInfo count: 210, type: ESTIMATED, armsInterventionsModule interventions name: musical application, outcomesModule primaryOutcomes measure: Means of subjective pain scores, primaryOutcomes measure: Means of body temperature (0C), primaryOutcomes measure: Means of systolic blood pressure (mmHg), primaryOutcomes measure: Means of diastolic blood pressure (mmHg), primaryOutcomes measure: Means of heart rate (/minutes), primaryOutcomes measure: Means of respiratory rate (/minutes), primaryOutcomes measure: Means of oxygen saturation (%), primaryOutcomes measure: Means of subjective anxiety scores, primaryOutcomes measure: Means of Perianesthesia Comfort Scale Scores, primaryOutcomes measure: Means of Patient Satisfaction Survey on Nursing Care Quality Scores, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Kocaeli University Hospital, city: Kocaeli, state: Umuttepe Campus, İzmit, zip: 41380, country: Turkey, geoPoint lat: 39.62497, lon: 27.51145, hasResults: False
protocolSection identificationModule nctId: NCT06293235, orgStudyIdInfo id: 2024/2120, briefTitle: Towards Optimal Fertility, Fathering and Fatherhood studY, acronym: TOFFFY, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-07, primaryCompletionDateStruct date: 2026-06, completionDateStruct date: 2027-03, studyFirstPostDateStruct date: 2024-03-05, lastUpdatePostDateStruct date: 2024-03-05, sponsorCollaboratorsModule leadSponsor name: KK Women's and Children's Hospital, class: OTHER_GOV, descriptionModule briefSummary: This case-control study involving fertile and subfertile couples aims to identify male factors related to pregnancy likelihood, create a fertility index measure combining male and female factors to predict pregnancy likelihood, and examine how male factors relate to the semen physical and biological characteristics., conditionsModule conditions: Reproductive Issues, conditions: Fertility Issues, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 960, type: ESTIMATED, armsInterventionsModule interventions name: Lifestyle and metabolic indicators, outcomesModule primaryOutcomes measure: Pregnancy rate, secondaryOutcomes measure: Fertility index, secondaryOutcomes measure: Oxidative stress, secondaryOutcomes measure: Semen volume, secondaryOutcomes measure: Sperm concentration, secondaryOutcomes measure: Sperm total motility, secondaryOutcomes measure: Sperm progressive motility, secondaryOutcomes measure: Total progressive motile sperm count, secondaryOutcomes measure: Single strand sperm DNA fragmentation, secondaryOutcomes measure: Double strand sperm DNA fragmentation, secondaryOutcomes measure: mRNA level, secondaryOutcomes measure: sncRNA level, secondaryOutcomes measure: DNA methylation, otherOutcomes measure: Sperm morphology, eligibilityModule sex: ALL, minimumAge: 21 Years, maximumAge: 49 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06293222, orgStudyIdInfo id: SCD Support, briefTitle: Patient and Public Involvement and Engagement in Research With Children and Young People With Sickle Cell Disorder and Their Families, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-08-21, primaryCompletionDateStruct date: 2024-04-30, completionDateStruct date: 2024-04-30, studyFirstPostDateStruct date: 2024-03-05, lastUpdatePostDateStruct date: 2024-03-07, sponsorCollaboratorsModule leadSponsor name: King's College London, class: OTHER, collaborators name: Sickle Cell Society, descriptionModule briefSummary: Aim: To co-produce resources for inclusive and equitable Patient and Public Involvement and Engagement in research on life-limiting conditions, with children and young people with sickle cell disorder and their families.Methods: Workshops with a) members of a patient advocacy organisation (Sickle Cell Society n=5) b): i) Children and young people (10-18 years) with sickle cell disorder (n=15) and ii) their siblings (10-18 years, n=10) and iii) their parents (n=15), c) Researchers form the Cicely Saunders Institute Outputs: Resources that enable children and young people with sickle cell disorder and their families to engage in research, conditionsModule conditions: Sickle Cell Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Workshops with participants to develop resources that enable children and young people with sickle cell disorder and their families to engage in research, eligibilityModule sex: ALL, minimumAge: 10 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: King's College London, city: London, zip: SE5 9RS, country: United Kingdom, geoPoint lat: 51.50853, lon: -0.12574, hasResults: False
protocolSection identificationModule nctId: NCT06293209, orgStudyIdInfo id: Sunpasitthiprasong Hospital, secondaryIdInfos id: Sunpasitthiprasong Hospital, type: OTHER, domain: Sunpasitthiprasong Hospital, briefTitle: Effect of Cool Spray and Cold Packs in Reducing Preoperative Edema and Pain in Ankle Fractures in Ubonratchathani, acronym: 3-armRCT, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-08-01, primaryCompletionDateStruct date: 2024-02-28, completionDateStruct date: 2024-05-28, studyFirstPostDateStruct date: 2024-03-05, lastUpdatePostDateStruct date: 2024-03-05, sponsorCollaboratorsModule leadSponsor name: Thai Traditional Medical Knowledge Fund, class: OTHER_GOV, descriptionModule briefSummary: The use of evaporative coolants in the management of acute musculoskeletal injury has received increasing attention recently. However, its efficacy compared with conventional cryotherapy in treating injured human subjects remains unclear.The purpose of this study is to compare the efficacy of evaporative coolants with that of ice packs in the preoperative management of edema and pain in patients with an ankle fracture, conditionsModule conditions: Ankle Fractures, conditions: Swelling, conditions: Cryotherapy Effect, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: PopulationThe sample group comprises 30 patients admitted for treatment in the male orthopedic surgery department, female orthopedic surgery department, and accident orthopedic surgery department at Sunpasitthiprasong Hospital, Ubon Ratchathani from August 2023 to January 2024. ., primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 90, type: ACTUAL, armsInterventionsModule interventions name: 3M cold pack, interventions name: Perskindol cold spray, interventions name: Placebo, outcomesModule primaryOutcomes measure: swelling, secondaryOutcomes measure: pain score, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Department of Orthopedics, Sunpasitthiprasong hospital, Ubonratchathani, Thailand., city: Multiple Locations, state: Ubonrachathani, zip: 34000, country: Thailand, hasResults: False
protocolSection identificationModule nctId: NCT06293196, orgStudyIdInfo id: 20231107, briefTitle: Effects of Acupoint Massage Around Eyes on Ocular Biological Indexes, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-09-01, primaryCompletionDateStruct date: 2024-03-31, completionDateStruct date: 2025-06-30, studyFirstPostDateStruct date: 2024-03-05, lastUpdatePostDateStruct date: 2024-03-05, sponsorCollaboratorsModule leadSponsor name: Zhongnan Hospital, class: OTHER, descriptionModule briefSummary: This study aims to investigate whether the acupoint eye exercise could impact the biological parameters of the eye., conditionsModule conditions: Investigating the Effects of Periocular Acupressure on Ocular Biological Indicators, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 55, type: ESTIMATED, armsInterventionsModule interventions name: acupressure, outcomesModule primaryOutcomes measure: Changes in blood flow to the eye, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Zhongnan Hospital of Wuhan University, status: RECRUITING, city: Wuhan, state: Hubei, zip: 430000, country: China, contacts name: Min Ke, doctor of medicine, role: CONTACT, phone: 18672395959, email: Keminyk@163.com, geoPoint lat: 30.58333, lon: 114.26667, hasResults: False
protocolSection identificationModule nctId: NCT06293183, orgStudyIdInfo id: EGE-HEM-STO-01, briefTitle: The Effect of Artificial Intelligence Supported Mobile Learning on Nutrition/Hydration Control and Individual Management, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-04, primaryCompletionDateStruct date: 2024-09-30, completionDateStruct date: 2024-12-30, studyFirstPostDateStruct date: 2024-03-05, lastUpdatePostDateStruct date: 2024-03-05, sponsorCollaboratorsModule leadSponsor name: Ege University, class: OTHER, descriptionModule briefSummary: The adherence to recommended nutrition and fluid restrictions is crucial for the success of hemodialysis treatment. However, approximately 80% of patients receiving HD treatment are non-compliant with fluid restriction, leading to various complications. Cardiovascular complications are among the most common complications associated with this issue. When reviewing national and international literature on the subject, it is observed that in order to improve treatment adherence in HD patients, written materials are often used in addition to individual or group education sessions, focusing mainly on assessing patients\&#39; quality of life and self-efficacy. However, a mobile-supported learning method that enables patients to manage their nutrition and fluid control individually is not commonly utilized.This research aims to investigate the impact of an artificial intelligence-supported mobile application developed for HD patients on the control of nutrition/fluid intake and individual management., conditionsModule conditions: Cronich Kidney Disease, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 76, type: ESTIMATED, armsInterventionsModule interventions name: Mobile app, outcomesModule primaryOutcomes measure: Fluid intake compliance, secondaryOutcomes measure: Change of individual management, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06293144, orgStudyIdInfo id: yuewei20231129, briefTitle: the 95% Effective Dose of Ciprofol for Adjunctive Sedation Undergoing Knee Arthroplasty in Elderly People, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-11-29, primaryCompletionDateStruct date: 2024-05, completionDateStruct date: 2024-05, studyFirstPostDateStruct date: 2024-03-05, lastUpdatePostDateStruct date: 2024-03-05, sponsorCollaboratorsModule leadSponsor name: Second Hospital of Shanxi Medical University, class: OTHER, descriptionModule briefSummary: Regional anesthesia is a common clinical anesthesia method, and regional anesthesia-assisted sedation play a central role in promoting patient comfort and relieving anxiety. With increasing age, elderly people experience changes in pharmacokinetics and pharmacodynamics and increased drug sensitivity. Ciprofol has advantages in adverse events such as hypotension and respiratory depression. There are fewer studies on the recommended dosage of ciprofol-assisted sedation for intrathecal anesthesia in elderly patients. The aim of study is to identify the 95% effective dose of ciprofol-assisted sedation in elderly patients undergoing spinal anesthesia using a biased coin design up-and-down sequential method(BCD-UDM), conditionsModule conditions: Sedation, conditions: ED95, conditions: Knee Arthroplasty, designModule studyType: INTERVENTIONAL, phases: EARLY_PHASE1, designInfo allocation: NA, interventionModel: SEQUENTIAL, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 70, type: ESTIMATED, armsInterventionsModule interventions name: Ciprofol, outcomesModule primaryOutcomes measure: Modified Alertness Sedation Score (MOAA/S), primaryOutcomes measure: Bispectral index (BIS), secondaryOutcomes measure: systolic blood pressure （SBP）, secondaryOutcomes measure: diastolic blood pressure（DBP）, secondaryOutcomes measure: heart rate (HR), secondaryOutcomes measure: pulse oxygen saturation（SpO2）, otherOutcomes measure: Occurrence of Sedation-related adverse events, eligibilityModule sex: ALL, minimumAge: 65 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Second Hospital of Shanxi Medical University, status: RECRUITING, city: Taiyuan, state: Shanxi, zip: 030001, country: China, contacts name: Zheng Guo, M.B.,Ph.D., role: CONTACT, phone: +863513365790, email: guozheng713@yahoo.com, geoPoint lat: 37.86944, lon: 112.56028, hasResults: False
protocolSection identificationModule nctId: NCT06293131, orgStudyIdInfo id: yuewei20230705, briefTitle: Median Effective Dose of Ciprofol-Assisted Sedation for Elderly Patients Undergoing Knee Arthroplasty, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-05-29, primaryCompletionDateStruct date: 2023-09-28, completionDateStruct date: 2023-09-28, studyFirstPostDateStruct date: 2024-03-05, lastUpdatePostDateStruct date: 2024-03-05, sponsorCollaboratorsModule leadSponsor name: Second Hospital of Shanxi Medical University, class: OTHER, descriptionModule briefSummary: Regional anesthesia is a common clinical anesthesia method, and regional anesthesia-assisted sedation play a central role in promoting patient comfort and relieving anxiety. With increasing age, elderly people experience changes in pharmacokinetics and pharmacodynamics and increased drug sensitivity. Ciprofol has advantages in adverse events such as hypotension and respiratory depression. There are fewer studies on the recommended dosage of ciprofol-assisted sedation for intrathecal anesthesia in elderly patients. The aim of study is to identify the median effective dose(ED50) of ciprofol-assisted sedation in elderly patients undergoing spinal anesthesia, conditionsModule conditions: Sedation, conditions: ED50, conditions: Knee Arthroplasty, designModule studyType: INTERVENTIONAL, phases: EARLY_PHASE1, designInfo allocation: NA, interventionModel: SEQUENTIAL, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 70, type: ACTUAL, armsInterventionsModule interventions name: Ciprofol, outcomesModule primaryOutcomes measure: Modified Alertness Sedation Score (MOAA/S), primaryOutcomes measure: Bispectral index (BIS), secondaryOutcomes measure: systolic blood pressure （SBP）, secondaryOutcomes measure: diastolic blood pressure（DBP）, secondaryOutcomes measure: heart rate (HR), secondaryOutcomes measure: pulse oxygen saturation（SpO2）, otherOutcomes measure: Occurrence of Sedation-related adverse events, eligibilityModule sex: ALL, minimumAge: 65 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Second Hospital of Shanxi Medical University, city: Taiyuan, state: Shanxi, zip: 030001, country: China, geoPoint lat: 37.86944, lon: 112.56028, hasResults: False
protocolSection identificationModule nctId: NCT06293118, orgStudyIdInfo id: 71055423.3.0000.0071, briefTitle: The Effects of Ischemic Conditioning in Individuals With Parkinson's Disease, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2026-04-01, completionDateStruct date: 2028-01-15, studyFirstPostDateStruct date: 2024-03-05, lastUpdatePostDateStruct date: 2024-03-05, sponsorCollaboratorsModule leadSponsor name: Hospital Israelita Albert Einstein, class: OTHER, descriptionModule briefSummary: Ischemic conditioning (IC) is a promising therapy that can mimic the physiological effects of physical exercise. IC consists of using a cuff to measure blood pressure and calibrate 200 mmHg on the upper or lower limb. Thus, at alternating intervals of 5 minutes, ischemia or reperfusion occurs, depending on whether the cuff is inflated or deflated. IC induces changes in spinal cord excitability for the last reflex reactions of recruited motoneurons with improved balance control in healthy young people and improved learning in the elderly. The objective of the present study is to evaluate the chronic effect of IC on the motor function and cognitive performance of patients with Parkinson's disease. Furthermore, the investigators will evaluate secondary outcomes such as mobility, quality of life, and immunological responses., conditionsModule conditions: Parkinson Disease, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: 1. Ischemic conditioning group2. control group (Sham), primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: Patients were unaware of the allocation., whoMasked: PARTICIPANT, enrollmentInfo count: 34, type: ESTIMATED, armsInterventionsModule interventions name: Ischemic conditioning group, interventions name: Sham group, outcomesModule primaryOutcomes measure: Motor function, primaryOutcomes measure: Cognitive performance, secondaryOutcomes measure: PDQ-39, secondaryOutcomes measure: Timed up and go (TUG), secondaryOutcomes measure: Assessment of cellular and soluble immune response, secondaryOutcomes measure: Quantifications of systemic soluble mediators, secondaryOutcomes measure: PBMC acquisition and flow cytometry, eligibilityModule sex: ALL, minimumAge: 40 Years, maximumAge: 90 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False