protocolSection identificationModule nctId: NCT06306053, orgStudyIdInfo id: 2022/ST/217, briefTitle: A New Treatment for Chronic Pain Combining Neuromodulation, Computer Assisted Training and Telemonitoring, acronym: TechNoPain, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2026-01-31, completionDateStruct date: 2026-04-30, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: ASST Santi Paolo e Carlo, class: OTHER, collaborators name: University of Milan, collaborators name: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, collaborators name: Istituto Europeo di Oncologia, descriptionModule briefSummary: Chronic pain (CP) is a leading cause of medical disability, healthcare expenditure, and reduced psychological well-being. Given the limited mobility, travel burden, and cost, access to care can be problematic for patients suffering from this disease, driving the recent shift toward care through telehealth programs. Given the complex interrelationship of physical and psychosocial aspects related to chronic pain, in this project the investigators propose to validate and investigate the effectiveness of new integrated health interventions by combining the technique of transcranial direct current stimulation (tDCS), complementary therapies and telemonitoring. The investigators hypothesize that this novel combined approach will provide a more effective strategy to overcome the classic barriers of pharmacological treatments and access to healthcare due to lack of mobility. To do this, the investigators will rely on a previously developed integrated platform that enables effective delivery of non-pharmacological interventions and outcome assessment. Many patients do not benefit from pharmacological and invasive treatments, leading to the development of alternative therapeutic options such as non-invasive brain stimulation (e.g. tDCS) and complementary interventions to improve physical and psychological well-being. These complementary interventions reduced pain intensity and psychological distress by improving individuals' ability to manage and cope with their pain. However, due to the multiple co-occurring factors associated with chronic pain, a multidisciplinary and integrated treatment approach is challenging. Technology ecosystems can be a reliable tool to achieve such a diverse personalized approach and evaluate their results. In a previous project, the investigators developed PainRE-Life, a dynamic and integrated technology ecosystem to enable continuity of care for CP patients, including personalized applications, training tools and telemonitoring tools for outcome assessment., conditionsModule conditions: Pain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 126, type: ESTIMATED, armsInterventionsModule interventions name: tDCS+EuleriaLab, interventions name: tDCS, interventions name: EuleriaLab, outcomesModule primaryOutcomes measure: Visual Analogue Scale (VAS), secondaryOutcomes measure: 12-item Short Form Survey (SF12), secondaryOutcomes measure: Hospital Anxiety and Depression scale (HADS), secondaryOutcomes measure: Brief Pain Inventory (BPI), secondaryOutcomes measure: Pain Catastrophizing Scale (PCS), secondaryOutcomes measure: Shared Decision-Making Questionnaire 9-Item (SDM-Q-9), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: ASST-Santi Paolo e Carlo Hospital, city: Milan, country: Italy, contacts name: Alberto Priori, PhD, role: CONTACT, geoPoint lat: 45.46427, lon: 9.18951, locations facility: Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, city: Milan, country: Italy, contacts name: Fabiana Ruggiero, PsYD, role: CONTACT, geoPoint lat: 45.46427, lon: 9.18951, locations facility: Istituto Europeo di Oncologia, city: Milan, country: Italy, contacts name: Gabriella Pravettoni, PhD, role: CONTACT, geoPoint lat: 45.46427, lon: 9.18951, hasResults: False