protocolSection identificationModule nctId: NCT06350656, orgStudyIdInfo id: IRBN282022/CHUSTE, briefTitle: Study of Cerebral Compliance in Neurosurgical Intensive Care Units (EC2), acronym: EC2, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-03-31, primaryCompletionDateStruct date: 2024-04, completionDateStruct date: 2024-04, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Centre Hospitalier Universitaire de Saint Etienne, class: OTHER, descriptionModule briefSummary: Despite the massive use of intracranial pressure in neuro-resuscitation, there is still no cerebral compliance evaluation index used in current practice to guide therapy.In treatment guidelines for intracranial hypertension, patients are placed in a prone position at about 30 degrees. Several times a day, during nursing care, patients are flattened, which corresponds to a cerebral compliance test by adding a volume of cerebrospinal fluid to the cranial box., conditionsModule conditions: Cerebrospinal; Disorder, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Clinical data collection, interventions name: Therapeutic data collection, interventions name: IntraCranial Pression (ICP) values collection, outcomesModule primaryOutcomes measure: Intracranial pressure (mmHg), secondaryOutcomes measure: Correlation between ICP (Intra Cranial Pressure) doses and cerebral compliance, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: CENTRE HOSPITALIER Charponnay, status: RECRUITING, city: Chaponnay, zip: 69970, country: France, contacts name: PIERRE-HENRI MURGAT, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 45.63097, lon: 4.94299, locations facility: CENTRE HOSPITALIER UNIVERSITAIRE Grenoble, status: RECRUITING, city: Grenoble, zip: 38000, country: France, contacts name: JEAN FRANCOIS PAYEN, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 45.16667, lon: 5.71667, locations facility: HOPITAL NORD La Tronche, status: RECRUITING, city: La Tronche, zip: 38170, country: France, contacts name: KEVIN LAGARDE, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 45.20429, lon: 5.73645, locations facility: APHP, status: RECRUITING, city: Paris, zip: 75010, country: France, contacts name: SAMUEL GAUGUIN, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 48.85341, lon: 2.3488, locations facility: Hopital Lariboisiere - Ahph, status: RECRUITING, city: Paris, zip: 75010, country: France, contacts name: JEROME CARTAILLIER, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 48.85341, lon: 2.3488, locations facility: CENTRE HOSPITALIER UNIVERSITAIRE Rennes, status: RECRUITING, city: Rennes, zip: 35000, country: France, contacts name: YOANN LAUNEY, MD PHD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 48.11198, lon: -1.67429, locations facility: CENTRE HOSPITALIER UNIVERSITAIRE Saint-Etienne, status: RECRUITING, city: Saint-Étienne, zip: 42055, country: France, contacts name: CLEMENT MAGAND, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 45.43389, lon: 4.39, hasResults: False