hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06320132, orgStudyIdInfo id: BLANDISH, briefTitle: BLANDISH (Brain, Loss of Function, Aneurism, Disease, Injury, Stroke, Hemorrhage), acronym: BLANDISH, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-13, primaryCompletionDateStruct date: 2028-12-31, completionDateStruct date: 2029-01-31, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: IRCCS Ospedale San Raffaele, class: OTHER, descriptionModule briefSummary: The goal of this observational study is to train a machine learning system based on data from patients affected by spontaneous Intracranial Hemorrage. The main question it aims to answer is whether there is a correlation between actual clinical pratice, reached outcomes and favorable or unfavorable predictive factors, and anamnesis.Participants will be treated as per standard clinical practice., conditionsModule conditions: Intracranial Hemorrhages, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 2000, type: ESTIMATED, armsInterventionsModule interventions name: Treatment of spontaneous intracranial hemorrhage, outcomesModule primaryOutcomes measure: Mortality, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: IRCCS Ospedale San Raffaele, status: RECRUITING, city: Milano, state: MI, country: Italy, contacts name: Francesca Guzzo, MD, role: CONTACT, phone: +393470830669, phoneExt: +390226433333, email: guzzo.francesca@hsr.it, contacts name: Margherita Tozzi, MD, role: CONTACT, phone: +393343138755, phoneExt: +390226433333, email: tozzi.margherita@hsr.it, geoPoint lat: 45.46427, lon: 9.18951, hasResults: False
protocolSection identificationModule nctId: NCT06320106, orgStudyIdInfo id: GIP 1021, briefTitle: Assessment of Navigation Abilities in Children With Cerebral Palsy and Their Peers, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-02-07, primaryCompletionDateStruct date: 2025-01-31, completionDateStruct date: 2025-01-31, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: IRCCS Eugenio Medea, class: OTHER, descriptionModule briefSummary: Spatial navigation skills are very important in everyday activities and quality of life but spatial navigation abilities are not part of the standard process of assessment and rehabilitation of patients. Furthermore, it is known that children with cerebral palsy have impaired visuo-spatial competences. The main objective of this study is to evaluate and compare the spatial navigation abilities of typically developing children and of children with cerebral palsy using the "StarMaze" application delivered by means of a Head Mounted Display (HMD). The second aim is to investigate the user experience during the session. A similar application was already developed and tested in a virtual reality large scale platform whose size and cost limit the accessibility. Therefore, the assessment (and future training) of navigation abilities with affordable and easy-to-use technology such as HMD open new perspectives., conditionsModule conditions: Cerebral Palsy, conditions: Healthy Volunteers, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 26, type: ESTIMATED, armsInterventionsModule interventions name: Virtual Reality baseline assessment, outcomesModule primaryOutcomes measure: Navigation strategy, secondaryOutcomes measure: Learning rate, secondaryOutcomes measure: Simulator Sickness Questionnaire, secondaryOutcomes measure: System Usability Scale, secondaryOutcomes measure: Independent Television Commission-Sense of Presence Inventory, secondaryOutcomes measure: Suitability Evaluation Questionnaire - simplified version, secondaryOutcomes measure: Short-form of PANAS-Positive Affect and Negative Affect Scales, eligibilityModule sex: ALL, minimumAge: 13 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Scientific Institute, IRCCS E. Medea, status: RECRUITING, city: Bosisio Parini, state: Lecco, zip: 23842, country: Italy, contacts name: Emilia Biffi, PhD, role: CONTACT, phone: +39 31877862, email: emilia.biffi@lanostrafamiglia.it, contacts name: Emilia Biffi, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 45.80075, lon: 9.29, hasResults: False
protocolSection identificationModule nctId: NCT06320093, orgStudyIdInfo id: INRCA_002_2024, briefTitle: Training Social and Health Care prOfessionals in mUsic-based Therapeutic iNterventions to Support Older People With Dementia, acronym: SOUND, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-10-03, primaryCompletionDateStruct date: 2024-02-20, completionDateStruct date: 2024-02-20, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: Istituto Nazionale di Ricovero e Cura per Anziani, class: OTHER, collaborators name: European Union, descriptionModule briefSummary: The study will investigate the effects of an inovative intervention based on the use of music on 45 professionals in the field of dementia, 45 elderly people with dementia., conditionsModule conditions: Dementia, conditions: Older People, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 45, type: ACTUAL, armsInterventionsModule interventions name: SOUND Intervention, outcomesModule primaryOutcomes measure: Change in mental wellbeing of patients with dementia, primaryOutcomes measure: Change in cognitive status of patients with dementia, primaryOutcomes measure: Change in stress of health care providers, eligibilityModule sex: ALL, minimumAge: 65 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: INRCA Hospital, city: Ancona, zip: 60127, country: Italy, geoPoint lat: 43.5942, lon: 13.50337, locations facility: Sons do Estamine Associacao, city: Trofa, country: Portugal, locations facility: Associatia Habilitas, city: Bucarest, country: Romania, geoPoint lat: 44.43225, lon: 26.10626, hasResults: False
protocolSection identificationModule nctId: NCT06320080, orgStudyIdInfo id: TQB2223-AK105-Ib-01, briefTitle: Clinical Study of TQB2223 Injection Combined With AK105 Injection in the Treatment of Advanced Hepatocellular Carcinoma., statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-02, completionDateStruct date: 2025-10, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: Chia Tai Tianqing Pharmaceutical Group Co., Ltd., class: INDUSTRY, descriptionModule briefSummary: TQB2223 is a recombinant, fully human antibody that binds to lymphocyte activation gene-3 (LAG-3) and blocks the LAG-3/ major histocompatibility complex class II (MHC-II) interaction, thus allowing for increased T-cell proliferation and cytokine production. This is a phase Ib study aimed at evaluating the safety, tolerability, and immunogenicity characteristics of TQB2223 injection combined with AK105 injection in the treatment of advanced hepatocellular carcinoma., conditionsModule conditions: Advanced Hepatocellular Carcinoma, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 34, type: ESTIMATED, armsInterventionsModule interventions name: TQB2223 injection, interventions name: Penpulimab Injection, outcomesModule primaryOutcomes measure: Objective Response Rate (ORR), primaryOutcomes measure: Progression-free survival (PFS), secondaryOutcomes measure: Overall survival (OS), secondaryOutcomes measure: Disease control rate (DCR), secondaryOutcomes measure: Duration of Response (DOR), secondaryOutcomes measure: Number of patients with adverse events (AEs) and/or serious adverse events (SAEs), secondaryOutcomes measure: Immunogenicity, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Affiliated Cancer Hospital of Harbin Medical University, city: Harbin, state: Heilongjiang, zip: 150000, country: China, contacts name: Zhiwei Li, Doctor, role: CONTACT, phone: 15004683651, email: lzhw0451@163.com, geoPoint lat: 45.75, lon: 126.65, locations facility: Hubei Provincial Tumor Hospital, city: Wuhan, state: Hubei, zip: 430079, country: China, contacts name: Feng Zhang, Doctor, role: CONTACT, phone: 13871410719, email: zhangfeng_329@126.com, geoPoint lat: 30.58333, lon: 114.26667, locations facility: Hunan Provincial Tumor Hospital, city: Changsha, state: Hunan, zip: 410031, country: China, contacts name: Shanzhi Gu, Master, role: CONTACT, phone: 13574865998, email: 105575191@qq.com, geoPoint lat: 28.19874, lon: 112.97087, hasResults: False
protocolSection identificationModule nctId: NCT06320054, orgStudyIdInfo id: PRO00049771, briefTitle: Preventing Obstetric Complications With Dietary Intervention, acronym: PLATE, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2025-06-30, completionDateStruct date: 2025-08-31, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: Medical College of Wisconsin, class: OTHER, collaborators name: Advancing a Healthier Wisconsin Endowment, collaborators name: Food for Health, Inc., descriptionModule briefSummary: The goal of this study is to learn whether access to healthy and fresh food, health coaching, and nutrition support intervention can reduce adverse birth outcomes in pregnant women. The main questions it aims to answer are:* Does access to healthy and fresh food, health coaching and nutrition support reduce the risk of gestational diabetes or preeclampsia and ultimately improve health outcomes for mothers and their newborns?* Are participants able to successfully utilize the health program? Are participants satisfied and self-equipped to apply the teachings of the program within their lives following their participation in the study? Participants will be randomly assigned to one of two groups.Participants in the standard of care will be asked to:* Complete surveys* Biometric screeningsParticipants in the intervention group will be asked to:* Complete surveys* Biometric screenings* Participate in weekly personal health coaching* Receive and consume provided weekly meals.Researchers will compare the standard of care to those who receive the intervention to see the impact of the intervention on clinical outcomes including: gestational weight gain, blood pressure, diagnosis of gestational diabetes, diagnosis of gestational hypertension or preeclampsia, and gestational age at birth., conditionsModule conditions: Gestational Diabetes, conditions: Gestational Hypertension, conditions: High Risk Pregnancy, conditions: Preeclampsia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Maternal Health Management Program, outcomesModule primaryOutcomes measure: Clinical Outcomes, primaryOutcomes measure: Clinical Outcomes, primaryOutcomes measure: Clinical Outcomes, primaryOutcomes measure: Clinical Outcomes, primaryOutcomes measure: Clinical Outcomes, secondaryOutcomes measure: Patient Reported Outcomes, secondaryOutcomes measure: Patient Reported Outcomes, secondaryOutcomes measure: Patient Reported Outcomes, secondaryOutcomes measure: Patient Reported Outcomes, secondaryOutcomes measure: Patient Reported Outcomes, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06320041, orgStudyIdInfo id: KY-2024-028, briefTitle: Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-12-30, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: The Fourth Affiliated Hospital of Zhejiang University School of Medicine, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial\] is to further explore the effectiveness and safety of oxelidine in the treatment of moderate to severe acute pain after orthopedic surgery. The main question it aims to answer is: Pain management after orthopaedic surgery provides more effective and safe drug options, provides new options for clinical treatment, and provides a scientific basis for clinical practice.Participants will be asked to pain score in the different time, treatments they'll be given and use optimal drug. Researchers will compare analgesic effect of oxelidine of different dose., conditionsModule conditions: Postoperative Pain, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 162, type: ESTIMATED, armsInterventionsModule interventions name: Low dose oxelidine group, interventions name: High dose oxelidine group, interventions name: Hydromorphone group, outcomesModule primaryOutcomes measure: Pain score at rest 0-72 hours after surgery, secondaryOutcomes measure: The total amount of opioid after operation., secondaryOutcomes measure: PCIA as a remedial analgesic press time, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 100 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06320015, orgStudyIdInfo id: R01CE003632-01-00, secondaryIdInfos id: R01CE003632, type: NIH, link: https://reporter.nih.gov/quickSearch/R01CE003632, briefTitle: Emergency Medicine Peer Outreach Worker Engagement for Recovery, acronym: EMPOWER, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-08-01, primaryCompletionDateStruct date: 2025-01, completionDateStruct date: 2025-09, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: University of California, Los Angeles, class: OTHER, collaborators name: Rhode Island Hospital, collaborators name: The Miriam Hospital, collaborators name: Brown University, descriptionModule briefSummary: This is an observational, prospective case-control study evaluating the effects of an emergency department community health worker-peer recovery specialist program (PCHW), the Substance Misuse Assistance Response Team (SMART). Aims of this study are to 1) understand participant experiences working with a SMART PCHW and identify possible mechanisms for successful recovery linkage; 2) Evaluate SMART effectiveness on patient-centered outcomes, building recovery capital, and recovery linkage; 3) Evaluate SMART implementation and effectiveness on patient outcomes over time.Using a combination of surveys and data linkages to state administrative databases, study investigators will prospectively compare changes in addiction treatment engagement, recovery capital, health related social needs, acute care utilization, and death between people receiving a ED PCHW and those who do not. After consenting to study participation, participants will complete surveys at time of study enrollment and 3 and 6 months after their initial ED visit. Primary outcomes include engagement in addiction treatment, social services engagement, acute care utilization, and mortality will be assessed through linkages to state administrative databases., conditionsModule conditions: Substance Use Disorders, conditions: Overdose, conditions: Opioid Use Disorder, conditions: Alcohol Use Disorder, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 400, type: ESTIMATED, armsInterventionsModule interventions name: Substance Misuse Assistance Response Team (SMART), outcomesModule primaryOutcomes measure: Treatment engagement, primaryOutcomes measure: Recovery Capital, secondaryOutcomes measure: Emergency Department Utilization, secondaryOutcomes measure: Repeat Hospitalization, secondaryOutcomes measure: Repeat Overdose, secondaryOutcomes measure: Mortality, secondaryOutcomes measure: Social Services Engagement, secondaryOutcomes measure: Housing Services Engagement, secondaryOutcomes measure: Employment, secondaryOutcomes measure: Incarceration, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06320002, orgStudyIdInfo id: 2023P003564, briefTitle: Communication Intervention for Fecal Ostomy Surgery, acronym: CI-oSurg, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-18, primaryCompletionDateStruct date: 2024-07-31, completionDateStruct date: 2024-08-30, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Massachusetts General Hospital, class: OTHER, descriptionModule briefSummary: In this study the investigators will evaluate the acceptability of a communication intervention for fecal ostomy surgery (CI-oSurg) to address the needs of adults who are undergoing fecal ostomy surgery. The investigators will recruit 24 patients and 4 clinicians (surgical nurses, wound ostomy nurses). At least half of patients are 65 years or older to understand the unique needs of older adults recovering from fecal ostomy surgery that might impact intervention acceptability. Questionnaires will be administered at two time-points for patient participants: upon study start and 4 weeks after exposure to the intervention., conditionsModule conditions: Surgery, conditions: Colostomy Stoma, conditions: Ileostomy - Stoma, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 28, type: ESTIMATED, armsInterventionsModule interventions name: Communication Intervention for fecal ostomy surgery, outcomesModule primaryOutcomes measure: Intervention Acceptability, secondaryOutcomes measure: Intervention Usability, otherOutcomes measure: Emotional Distress, otherOutcomes measure: World Health Organization Brief quality of life evaluation, otherOutcomes measure: Hospital Anxiety and Depression Scale, otherOutcomes measure: Therapy Evaluation Form, otherOutcomes measure: Client Satisfaction Questionnaire, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Massachusetts General Hospital, status: RECRUITING, city: Boston, state: Massachusetts, zip: 02114, country: United States, contacts name: Christy E Cauley, MD, role: CONTACT, phone: 617-726-8129, email: ccauley@mgb.org, geoPoint lat: 42.35843, lon: -71.05977, hasResults: False
protocolSection identificationModule nctId: NCT06319989, orgStudyIdInfo id: IRB202301905, briefTitle: The Efficacy of Biplane Versus Single Plane Ultrasound in Facilitating Caudal Epidural Anesthesia in Pediatric Patients., statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-25, primaryCompletionDateStruct date: 2026-03-25, completionDateStruct date: 2026-09-30, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: University of Florida, class: OTHER, descriptionModule briefSummary: Ultrasound guidance plays a pivotal role in caudal epidural block in pediatric patients. In comparison to conventional single-plane ultrasound, biplane ultrasound offers the advantage of providing simultaneous transverse and longitudinal imaging. Better visualization under biplane ultrasound is postulated to enhance the efficacy of caudal epidural blocks. This improvement is expected to manifest through higher first puncture success rate, shorter procedure time, and longer time to first postoperative analgesics use., conditionsModule conditions: Educational Problems, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: This is a prospective, randomized, parallel study to assess the efficacy of biplane ultrasound-guided caudal epidural anesthesia in pediatric patients., primaryPurpose: OTHER, maskingInfo masking: NONE, maskingDescription: The intervention group will receive caudal epidural block under the guidance of biplane ultrasound. The procedures for patients in the control group will be guided by conventional single-plane ultrasound., enrollmentInfo count: 281, type: ESTIMATED, armsInterventionsModule interventions name: Biplane Ultrasound, interventions name: Single plane ultrasound, outcomesModule primaryOutcomes measure: First puncture success, secondaryOutcomes measure: Number of Needle redirections, secondaryOutcomes measure: Duration of epidural, secondaryOutcomes measure: Postoperative analgesic use, eligibilityModule sex: MALE, minimumAge: 4 Months, maximumAge: 10 Years, stdAges: CHILD, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06319976, orgStudyIdInfo id: P.T.REC/012/004883, briefTitle: Effect of Rotator Cuff Training on Hand Grip in Adults, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-30, primaryCompletionDateStruct date: 2024-10-30, completionDateStruct date: 2024-12-30, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: Purpose of the study:* To investigate the effect of rotator cuff training on hand grip strength in adults with different body mass index.* To investigate the effect of rotator cuff training on hand grip static endurance in adults with different body mass index.* To investigate the effect of rotator cuff training on hand grip dynamic endurance in adults with different body mass index.* To investigate the effect of rotator cuff training on upper limb function in adults with different body mass index., conditionsModule conditions: Hand Grasp, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: open chain exercises for rotator cuff muscles, interventions name: Advices for postural correction, outcomesModule primaryOutcomes measure: Hand grip strength, secondaryOutcomes measure: Hand grip static endurance, secondaryOutcomes measure: Hand grip dynamic endurance, secondaryOutcomes measure: Upper limb function, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 35 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False