protocolSection identificationModule nctId: NCT06332872, orgStudyIdInfo id: M046q/66, briefTitle: Comparison Effectiveness of Oral Ivermectin, 1% Permethrin Shampoo and 4% Dimeticone Liquid Gel in the Treatment of Pediculosis Capitis Among School Children in Chachoengsao Province, Thailand, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-12-15, primaryCompletionDateStruct date: 2024-03-18, completionDateStruct date: 2024-05, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Phramongkutklao College of Medicine and Hospital, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to Comparison effectiveness of Oral ivermectin, 1% Permethrin shampoo and 4% Dimeticone liquid gel in the treatment of Pediculosis capitis, to assess the prevalence of lice and associated risk factors between severity groups by using questionnaire-based surveys and diagnostic tests among school children in Baan Nayao, Chachoengsao Province, Thailand.The main questions it aims to answer are* What is more effective between Oral ivermectin, 1% Permethrin shampoo and 4%Dimeticone liquid gel in the treatment of Pediculosis capitis in school children in Baan Nayao, Chachoengsao Province, Thailand?* What is Prevalence and risk factors of being infected with in head lice in school and community?* What is Side effects of Oral ivermectin, 1% Permethrin shampoo and 4%Dimeticone liquid gel?Participants will receive three different drugs are* oral ivermectin* 4% Dimeticone liquid gel* 1% Permethrin shampooParticipants voluntarily received oral ivermectin as per medical prescription, with treatment outcomes, side effects, and satisfaction levels monitored following two treatment cycles. Those exhibiting persistent lice infestations were subsequently treated with 1% permethrin shampoo, the standard treatment, while alternatives were provided for individuals allergic to permethrin. These findings will contribute to formulating tailored, effective, and safe treatment regimens for future patients., conditionsModule conditions: Pediculus Capitis Infestation, conditions: Permethrin Adverse Reaction, conditions: Dimethicone Adverse Reaction, conditions: Permethrin Allergy, conditions: Dimethicone Allergy, conditions: Ivermectin, conditions: School-age Children, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 117, type: ESTIMATED, armsInterventionsModule interventions name: Oral Ivermectin, interventions name: 4% dimenticone liquid gel, outcomesModule primaryOutcomes measure: Comparison effectiveness of Oral ivermectin, 1% Permethrin shampoo and 4% Dimeticone liquid gel in the treatment of Pediculosis capitis, secondaryOutcomes measure: Prevalence of head louse infestation among school children in Chachoengsao Province, Thailand, secondaryOutcomes measure: Side effects of Oral ivermectin, 1% Permethrin shampoo and 4%Dimeticone liquid gel, secondaryOutcomes measure: The association factor of head lice infestation among school children in Chachoengsao Province, Thailand, eligibilityModule sex: ALL, minimumAge: 6 Years, maximumAge: 13 Years, stdAges: CHILD, contactsLocationsModule locations facility: Phramongkutklao college of medicine, city: Bangkok, country: Thailand, geoPoint lat: 13.75398, lon: 100.50144, hasResults: False