protocolSection identificationModule nctId: NCT06374745, orgStudyIdInfo id: 2020-01307; mu24Kappos, briefTitle: An Integrated Algorithm for Surgical Intervention in Chronic Lymphedema After Breast Cancer Treatment: The Basel Lymphedema Protocol, statusModule overallStatus: RECRUITING, startDateStruct date: 2015-01-02, primaryCompletionDateStruct date: 2024-12-30, completionDateStruct date: 2024-12-30, studyFirstPostDateStruct date: 2024-04-19, lastUpdatePostDateStruct date: 2024-04-19, sponsorCollaboratorsModule leadSponsor name: University Hospital, Basel, Switzerland, class: OTHER, collaborators name: Sana Kliniken Düsseldorf GmbH, descriptionModule briefSummary: The primary objective of the investigators is to develop an integrated algorithm for surgical treatment of chronic lymphedema after breast cancer surgery. This will be achieved by retrospectively analysing a subgroup of patients who had breast cancer-related surgery prior to lymphedema., conditionsModule conditions: Lymphedema, conditions: Breast Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 500, type: ESTIMATED, outcomesModule primaryOutcomes measure: To design an integrated algorithm for surgical treatment of chronic lymphedema after breast cancer surgery., primaryOutcomes measure: Date of follow-up procedure, primaryOutcomes measure: Follow-up and type of lymphedema surgery, primaryOutcomes measure: Circumferences of the affected and unaffected side, primaryOutcomes measure: Postoperative complications, primaryOutcomes measure: Surgery duration., primaryOutcomes measure: Type of lymphedema surgery, primaryOutcomes measure: Date of lymphedema surgery, primaryOutcomes measure: Use of compression stockings, primaryOutcomes measure: Number of lymphedema drainages per week, primaryOutcomes measure: Stage of lymphedema, primaryOutcomes measure: Duration of lymphedema, primaryOutcomes measure: Location of lymphedema, primaryOutcomes measure: Subsequent cancer treatment, primaryOutcomes measure: Date of cancer related surgery, primaryOutcomes measure: Tumor staging, primaryOutcomes measure: Tumor location, primaryOutcomes measure: BMI, primaryOutcomes measure: Comorbidities, primaryOutcomes measure: Age, primaryOutcomes measure: Gender, secondaryOutcomes measure: Analysis of cohort subgroups: all patients who had surgery related to any kind of cancer prior to their lymphedema, secondaryOutcomes measure: Analysis of cohort subgroups: all patients who had surgery related to a specific kind of cancer prior to their lymphedema, e.g. vulvar, cervical or uterine cancer, secondaryOutcomes measure: Analysis of cohort subgroups: all patients who had no history of cancer and thus no cancer-related surgery in their medical history, secondaryOutcomes measure: Analysis of cohort subgroups: all patients with chronic lymphedema regardless of whether or not they have an oncological history, secondaryOutcomes measure: Analysis of cohort subgroups: all patients who underwent DIEP flap or TRAM flap or LDM flap or implant based breast reconstruction or BCS, secondaryOutcomes measure: Analysis of cohort subgroups: exploratory, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University Hospital Basel, status: RECRUITING, city: Basel, zip: 4031, country: Switzerland, contacts name: Elisabeth A Kappos, PD Dr. med., role: CONTACT, phone: 0041 61 265 25 25, email: elisabeth.kappos@usb.ch, contacts name: Adriano Fabi, BMed, role: CONTACT, phone: 0041 79 888 12 51, email: adriano.fabi@uzh.ch, geoPoint lat: 47.55839, lon: 7.57327, hasResults: False