protocolSection identificationModule nctId: NCT06365268, orgStudyIdInfo id: APHP231139, briefTitle: Perinatal Thoraco-abdomino-pelvic Tumors Study, acronym: CONTRAST, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2024-09, completionDateStruct date: 2024-09, studyFirstPostDateStruct date: 2024-04-15, lastUpdatePostDateStruct date: 2024-04-15, sponsorCollaboratorsModule leadSponsor name: Assistance Publique - Hôpitaux de Paris, class: OTHER, descriptionModule briefSummary: Congenital tumors are a rare diagnosis in the fetus and newborn. They differ from those of children and adults in terms of the nature, location and evolution of the tumor.Indeed, some histologically benign tumors may have lethal potential in utero (e.g. sacrococcygeal teratomas) or even undergo malignant transformation if left untreated. In contrast, other tumors that are malignant by histological criteria may have a very good prognosis, regressing spontaneously within the first year of life (e.g. neuroblastoma).Despite advances in imaging, benign and malignant solid tumors remain a major diagnostic and prognostic challenge in the antenatal context.The management of congenital tumors requires multidisciplinary expertise, taking into account the perinatal context, which poses specific problems, particularly in terms of therapeutic aspects, but also the frequent existence of associated malformations and/or genetic predisposition syndromes.This study focuses on solid tumors of the thoraco-abdomino-pelvic region, the main objective being to investigate the correlation between antenatal clinical and radiological analysis and confirmed postnatal diagnosis of congenital solid truncal tumors, as well as the developmental spectrum in which they fit., conditionsModule conditions: Perinatal Solid Tumors of the Thoraco-abdomino-pelvic Region, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Collection of data from the patient's medical file, outcomesModule primaryOutcomes measure: Correlation between antenatal clinico-radiological analysis and postnatal diagnosis of solid congenital truncal tumors, primaryOutcomes measure: Description of the developmental spectrum of solid congenital truncal tumors, secondaryOutcomes measure: Characteristics and location of the tumor on pre- and post-natal imaging, secondaryOutcomes measure: Ile-de-France epidemiology of perinatal tumors, secondaryOutcomes measure: Evolution of solid congenital truncal tumors, secondaryOutcomes measure: Associated genetic abnormalities and malformations, secondaryOutcomes measure: Intercurrent obstetric events and obstetric outcomes based on the diagnoses made, secondaryOutcomes measure: Development of a management algorithm based on prenatal findings, eligibilityModule sex: ALL, maximumAge: 3 Months, stdAges: CHILD, contactsLocationsModule locations facility: Hôpital Necker-Enfants Malades, city: Paris, zip: 75015, country: France, contacts name: Sabine SARNACKI, MD, PhD, role: CONTACT, phone: 1 44 49 41 94, phoneExt: +33, email: sabine.sarnacki@aphp.fr, geoPoint lat: 48.85341, lon: 2.3488, hasResults: False