protocolSection identificationModule nctId: NCT06302231, orgStudyIdInfo id: 16690919.5.0000.5347, briefTitle: Effects of Time-restricted Eating and Aerobic Exercise Training in Women With Overweight and Obesity, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-03-08, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Federal University of Rio Grande do Sul, class: OTHER, descriptionModule briefSummary: Time-restricted eating (TRE) is a dietary approach that aims to increase fasting time and decrease the eating window. Promising TRE effects on weight loss and improvements in some cardiometabolic risk factors have been reported in studies in animals and humans. However, the impacts of TRE combined with aerobic exercise training in individuals with overweight and obesity have been insufficiently investigated.Additionally, aerobic training performed in a fasted state appears to promote physiological adaptations that may improve the metabolic health in individuals with overweight and obesity.The present study investigates the effects of 8 weeks of TRE associated with aerobic training in a fasted state versus a fed state on body composition and cardiometabolic parameters in women with overweight and grade 1 obesity., conditionsModule conditions: Time Restricted Eating, conditions: Obesity, conditions: Intermittent Fasting, conditions: Overweight and Obesity, conditions: Time Restricted Feeding, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Dietary and Exercise Approaches, interventions name: Dietary and Exercise Approaches, interventions name: Dietary Approach, outcomesModule primaryOutcomes measure: Insulin sensitivity (indices), secondaryOutcomes measure: Insulin resistance (indices), secondaryOutcomes measure: Fasting insulin levels (µIU/mL), secondaryOutcomes measure: Fasting glucose levels (mg/dL), secondaryOutcomes measure: Glucose tolerance, secondaryOutcomes measure: Fasting lipid profile levels, secondaryOutcomes measure: β cell function (indices), secondaryOutcomes measure: Fat Mass (kg), secondaryOutcomes measure: Fat Percentage (%), secondaryOutcomes measure: Fat Free Mass (kg), secondaryOutcomes measure: Body Weight (kg), secondaryOutcomes measure: Body Weight (kg), secondaryOutcomes measure: Bone Mineral Content (kg), secondaryOutcomes measure: Body Mass Index (kg/m^2), secondaryOutcomes measure: Fasting ketones (β-hydroxybutyrate) levels (mmol/L), secondaryOutcomes measure: Resting metabolic rate (Kcal/day), secondaryOutcomes measure: Substrate Oxidation (respiratory exchange ratio), secondaryOutcomes measure: Absolute Peak oxygen consumption, secondaryOutcomes measure: Relative Peak oxygen consumption, secondaryOutcomes measure: Fasting Leptin Levels, secondaryOutcomes measure: Fasting Adiponectin Levels, secondaryOutcomes measure: Inflammatory Markers Levels, secondaryOutcomes measure: LDL-cholesterol levels, secondaryOutcomes measure: Non-HDL-cholesterol levels, eligibilityModule sex: FEMALE, minimumAge: 20 Years, maximumAge: 40 Years, stdAges: ADULT, hasResults: False