hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06324292, orgStudyIdInfo id: FDASU-RecID112324, briefTitle: Effect Of Digital Smile Design on Quality Of Life In Complete Denture Wearers, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-09-01, completionDateStruct date: 2024-09-15, studyFirstPostDateStruct date: 2024-03-21, lastUpdatePostDateStruct date: 2024-03-26, sponsorCollaboratorsModule leadSponsor name: Ain Shams University, class: OTHER, descriptionModule briefSummary: The aim of the current study protocol is to compare the effect of two complete dentures made for completely edentulous patients; one digitally constructed using digital smile design (DSD) and another one conventionally constructed on the patient's quality of life and patient's satisfaction.It is a clinical trial in which two dentures will be made for each patient, one will be digitally constructed using digital smile design (DSD) and the other one using the conventional method with a washout period of 3 weeks. Each patient will receive a questionnaire "Oral Health Impact Profile -19" (OHIP -19) for the edentulous patients to evaluate his satisfaction with the denture., conditionsModule conditions: Complete Edentulism, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: The participants allocated into two groups; a conventional denture followed by a digital group (CG) and a digital denture followed by a conventional one group (DG)., primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 24, type: ESTIMATED, armsInterventionsModule interventions name: complete denture, CG, interventions name: complete denture, DG, outcomesModule primaryOutcomes measure: quality of life assessment, eligibilityModule sex: ALL, minimumAge: 40 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule locations facility: Faculty of Dentistry Ain Shams University, city: Cairo, zip: 11361, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, locations facility: Faculty of Dentistry, Ain Shams University, city: Cairo, zip: 11361, country: Egypt, contacts name: ahmed MA mohamed, Bsc, Msc,MD, role: CONTACT, phone: 01111191337, phoneExt: 020, email: ahmedmostafa@dent.asu.edu.eg, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06324279, orgStudyIdInfo id: 000017585, briefTitle: Cervical Sliding Sign to Predict Outcome of Induction of Labor, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-09-01, primaryCompletionDateStruct date: 2024-04-01, completionDateStruct date: 2024-04-01, studyFirstPostDateStruct date: 2024-03-21, lastUpdatePostDateStruct date: 2024-03-21, sponsorCollaboratorsModule leadSponsor name: Ain Shams Maternity Hospital, class: OTHER, descriptionModule briefSummary: Assess the role of transvaginal ultrasound specifically a sign called cervical sliding sign, in the prediction of success of induction of labor.The prediction of outcome of induction of labor has always been an important topic to all obstetricians. Bishop score is traditionally considered reliable way to predict the outcome of induction of labor by assessing the cervical dilatation, effacement, position, and consistence and assessing the level of the fetal head in the birth canal. Since The bishop score remains a highly subjective method for prediction of outcome of induction of labor, the use of sonographic measurements such as cervical sliding sign can be a better predictor of successful induction of labor.The presence of CSS was defined as the sliding of the anterior cervical lip on the posterior one under gentle pressure of the transvaginal probe.Patients undergoing induction of labor with misoprostol will be checked for the cervical sliding sign. The mode of delivery, induction to active labor time and active labor to delivery time will be recorded and analysed to assess whether the sliding sign is an independent predictor of success of induction., conditionsModule conditions: Induction of Labor, conditions: Transvaginal Ultrasound: Cervical Sliding Sign, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 130, type: ACTUAL, armsInterventionsModule interventions name: Transvaginal ultrasound, interventions name: Misoprostol 200mcg Tab, outcomesModule primaryOutcomes measure: Mode of delivery, primaryOutcomes measure: Induction to active labor time, primaryOutcomes measure: Active labor to delivery time, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule locations facility: Maternity hospital, ainshams university hospitals, city: Cairo, zip: 11799, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06324266, orgStudyIdInfo id: 2023NZKY-044-02, briefTitle: Study on the Efficacy and Safety of Low-dose CTX as Maintenance Therapy for MM Unsuitable for Transplantation, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-04-16, primaryCompletionDateStruct date: 2025-12-31, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-03-21, lastUpdatePostDateStruct date: 2024-03-21, sponsorCollaboratorsModule leadSponsor name: Jinling Hospital, China, class: OTHER, descriptionModule briefSummary: The investigators will conduct randomized and controlled clinical studies in order to preliminarily explore the efficacy and safety of low-dose cyclophosphamide and lenalidomide in maintenance therapy for MM that is not suitable for transplantation in the standard-risk group., conditionsModule conditions: Newly Diagnosed Multiple Myeloma, designModule studyType: INTERVENTIONAL, phases: PHASE2, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Cyclophosphamide, interventions name: Lenalidomide, outcomesModule primaryOutcomes measure: PFS1, secondaryOutcomes measure: Incidence of Efficacy as assessed by IMWG, secondaryOutcomes measure: Incidence of Safety as assessed by CTCAE 4.0, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 100 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Jinling Hospital, status: RECRUITING, city: Nanjing, state: Jiangsu, country: China, contacts name: Zhao Qian, role: CONTACT, phone: 18251835035, email: 540598707@qq.com, geoPoint lat: 32.06167, lon: 118.77778, hasResults: False
protocolSection identificationModule nctId: NCT06324253, orgStudyIdInfo id: 1/24 UROL2, briefTitle: Thoracic Epidural Analgesia With Bilateral Erector Spinae Plane Block in Radical Cystectomy Surgery, acronym: TEAvsESB, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2024-05-10, completionDateStruct date: 2024-06-10, studyFirstPostDateStruct date: 2024-03-21, lastUpdatePostDateStruct date: 2024-03-21, sponsorCollaboratorsModule leadSponsor name: Menoufia University, class: OTHER, collaborators name: Amal Ismael Abdelrahman Hassan, collaborators name: Ibrahim Mowafy Gomaa Atawia, descriptionModule briefSummary: The aim of this study is to compare between Thoracic Epidural Analgesia (TEA) with ultrasound-guided bilateral erector spinae plane (ESP) block in radical cystectomy surgery for analgesic efficacy and hemodynamic effects, conditionsModule conditions: Post Operative Pain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Group A: will receive bilateral Erector Spinae Block after induction of anesthesia.Group B: will receive Thoracic Epidural Block before induction of anesthesia., primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 20, type: ACTUAL, armsInterventionsModule interventions name: bilateral Erector spine block,A dose of 30 ml 0.125% Bupivacaine will be injected., interventions name: Thoracic epidural analgesia, outcomesModule primaryOutcomes measure: Time for first rescue analgesia, secondaryOutcomes measure: Visual analogue scale score at 1st,2nd,4th,6th,8th,12th and 24 h (where 0 is interpreted as no pain, 1-4 mild pain, 5-6 moderate pain, 7-10 severe pain), secondaryOutcomes measure: the number of rescue analgesics within 24hrs after surgery, otherOutcomes measure: The heart rate, mean arterial blood pressure, otherOutcomes measure: Complications like bradycardia or hypotension, intraoperative and postoperative dysrhythmia, nausea and vomiting, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Menoufia university, city: Cairo, state: Shibin Elkom, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06324227, orgStudyIdInfo id: 311203003, briefTitle: Effects of Multimodal Music Intervention on Mild Cognitive Impairment Elderly, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-09-17, primaryCompletionDateStruct date: 2024-03-26, completionDateStruct date: 2024-05-26, studyFirstPostDateStruct date: 2024-03-21, lastUpdatePostDateStruct date: 2024-03-21, sponsorCollaboratorsModule leadSponsor name: National Yang Ming University, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to learn about whether music therapy can ameliorate cognitive function, physical fitness and psychology in mild cognitive impairment and mild dementia population. The main questions it aims to answer are:1. To build a model of multimodal music therapy.2. To discuss the effect of twelve-week multimodal music therapy in ameliorating community-based elders with MCI and mild dementia. Main outcome variables: cognitive function (Montreal Cognitive Assessment Scale, trail making test, Saint Louis University Mental Status Examination). Secondary outcome variables: physical fitness (muscle strength, muscular endurance, flexibility, balance ability), depression., conditionsModule conditions: Mild Cognitive Impairment, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: FACTORIAL, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: multimodal music therapy, interventions name: no intervention, outcomesModule primaryOutcomes measure: Montreal Cognitive Assessment, primaryOutcomes measure: Saint Louis University Mental Status, primaryOutcomes measure: Trail Making Test, secondaryOutcomes measure: 30s chair stand, secondaryOutcomes measure: back scratch test, secondaryOutcomes measure: sit and reach test, secondaryOutcomes measure: 8-foot up-and-go test, secondaryOutcomes measure: handgrip, secondaryOutcomes measure: Geriatric Depression Scale 15 items, eligibilityModule sex: ALL, minimumAge: 65 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: NationalYangMingU, status: RECRUITING, city: Taipei, country: Taiwan, contacts name: Wei Zu Lo, role: CONTACT, phone: 02-2823-9753, phoneExt: 66378, email: weitzu@nycu.edu.tw, geoPoint lat: 25.04776, lon: 121.53185, hasResults: False
protocolSection identificationModule nctId: NCT06324201, orgStudyIdInfo id: QDOT PAS, briefTitle: The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation., acronym: QDOT PAS, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-27, primaryCompletionDateStruct date: 2026-03, completionDateStruct date: 2028-03, studyFirstPostDateStruct date: 2024-03-21, lastUpdatePostDateStruct date: 2024-03-21, sponsorCollaboratorsModule leadSponsor name: Heart Rhythm Clinical and Research Solutions, LLC, class: OTHER, collaborators name: Biosense Webster, Inc., descriptionModule briefSummary: Observational, multi-center, non-randomized, post-market study. This is a nested sub-study of the REAL AF Registry. Consecutive symptomatic drug refractory paroxysmal atrial fibrillation (PAF) patients from the registry will be screened for enrollment to this sub-study per inclusion and exclusion criteria., conditionsModule conditions: Paroxysmal Atrial Fibrillation, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 250, type: ESTIMATED, armsInterventionsModule interventions name: Ablation Procedure, outcomesModule primaryOutcomes measure: Safety of the QDOT Micro System use in conjunction with VISITAG SURPOINT Module, primaryOutcomes measure: Effectiveness of the QDOT Micro System use in conjunction with VISITAG SURPOINT Module at 12-months., primaryOutcomes measure: Effectiveness of the QDOT Micro System use in conjunction with VISITAG SURPOINT Module at 24-months., primaryOutcomes measure: Effectiveness of the QDOT Micro System use in conjunction with VISITAG SURPOINT Module at 36-months., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Centra Health, Inc.dba Stroobants Cardiovascular Center, status: RECRUITING, city: Lynchburg, state: Virginia, zip: 24501, country: United States, contacts name: Cindy Baumann, role: CONTACT, contacts name: Mathhew Sackett, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 37.41375, lon: -79.14225, locations facility: Mercy Health, status: RECRUITING, city: Janesville, state: Wisconsin, zip: 53548, country: United States, contacts name: Kaitlyn Phetteplace, role: CONTACT, contacts name: Imdad Ahmed, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 42.68279, lon: -89.01872, hasResults: False
protocolSection identificationModule nctId: NCT06324162, orgStudyIdInfo id: JagiellonianU Gibas-Stanek, briefTitle: Does the Pain Experienced During Orthodontic Treatment and Bracket Removal Depend on the Architecture of the Bracket?, acronym: Debonding, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-10-01, primaryCompletionDateStruct date: 2023-05-01, completionDateStruct date: 2023-05-01, studyFirstPostDateStruct date: 2024-03-21, lastUpdatePostDateStruct date: 2024-03-21, sponsorCollaboratorsModule leadSponsor name: Piotr Fudalej, class: OTHER, descriptionModule briefSummary: The present research aimed to thoroughly investigate the impact of bracket architecture on pain perception during active treatment, debonding, and adhesive removal., conditionsModule conditions: Debonding, conditions: Orthodontic Brackets, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ACTUAL, armsInterventionsModule interventions name: bracket removal pliers, LODI, outcomesModule primaryOutcomes measure: Pain during active treatment, primaryOutcomes measure: Pain during brackets removal, primaryOutcomes measure: Pain on adhesive removal, eligibilityModule sex: ALL, minimumAge: 12 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Jagiellonian University Collegium Medicum, city: Kraków, zip: 31-008, country: Poland, geoPoint lat: 50.06143, lon: 19.93658, hasResults: False
protocolSection identificationModule nctId: NCT06324149, orgStudyIdInfo id: AGE-IT-FRAILTY, briefTitle: Age-related Conditions in the Context of Multimorbidity and Frailty: Relative Weight of Frailty in Determining the Course and Outcomes of Different Chronic Diseases and Viceversa, acronym: AGE-IT-FRAILTY, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2026-02-28, completionDateStruct date: 2026-04-30, studyFirstPostDateStruct date: 2024-03-21, lastUpdatePostDateStruct date: 2024-03-21, sponsorCollaboratorsModule leadSponsor name: IRCCS San Raffaele, class: OTHER, descriptionModule briefSummary: Observational study. Participants of the FRASNET study (9th March 2017, Protocol No. 24/INT/2017) who were evaluated in 2016 and 2017 will be contacted to be re-evaluated with multidimensional visits as part of the present study in order to assess trajectories and biomarkers of frailty and sarcopenia. Moreover, are going to evaluate with the same multidimensional visits patients with mild cognitive impairment and dementia followed up at the Neurologic Unit of the San Raffaele Hospital., conditionsModule conditions: Frailty, conditions: Sarcopenia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 500, type: ESTIMATED, armsInterventionsModule interventions name: completion of scales and questionnaires; venous blood sampling; muscle ultrasound; cardiac ultrasound; electrocardiogram; bioelectrical impedance analysis, outcomesModule primaryOutcomes measure: identify new molecular markers of frailty and sarcopenia, secondaryOutcomes measure: evaluate the ability of new markers for frailty, sarcopenia, cognitive impairment, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 100 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: San Raffaele Hospital, city: Milan, country: Italy, geoPoint lat: 45.46427, lon: 9.18951, hasResults: False
protocolSection identificationModule nctId: NCT06324123, orgStudyIdInfo id: 23C304, briefTitle: Observational Study Aimed at Evaluating the Trend of Neuropathic Pain, acronym: NEURATIL, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-06-09, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-21, lastUpdatePostDateStruct date: 2024-03-25, sponsorCollaboratorsModule leadSponsor name: Istituto Auxologico Italiano, class: OTHER, descriptionModule briefSummary: The present study aims to evaluate the trend of neuropathic pain in patients treated with Peacetil for a period of two months.Neuropathic pain will me assessed through the Numeric Rating Scale (NRS) questionnaire score., conditionsModule conditions: Neuropathic Pain, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 400, type: ESTIMATED, armsInterventionsModule interventions name: Peacetil, outcomesModule primaryOutcomes measure: Change in neuropathic pain after two months of treatment with Peacetil, secondaryOutcomes measure: Change in neuropathic pain after one month of treatment with Peacetil, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 82 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Istituto Auxologico Italiano, status: RECRUITING, city: Milan, state: Lombardy, zip: 20149, country: Italy, contacts name: Luca Maderna, MD, role: CONTACT, phone: 0261911, email: l.maderna@auxologico.it, contacts name: Alberto Doretti, MD, role: CONTACT, phone: 0261911, phoneExt: 2937, email: neurotrial@auxologico.it, geoPoint lat: 45.46427, lon: 9.18951, locations facility: ASST Fatebenefratelli Sacco, status: NOT_YET_RECRUITING, city: Milano, zip: 20157, country: Italy, contacts name: Fabrizio Gervasoni, MD, role: CONTACT, email: fabrizio.gervasoni@asst-fbf-sacco.it, geoPoint lat: 45.46427, lon: 9.18951, locations facility: Fondazione Don Carlo Gnocchi ONLUS, status: NOT_YET_RECRUITING, city: Milano, country: Italy, contacts name: Angela Comanducci, MD, role: CONTACT, email: acomanducci@dongnocchi.it, geoPoint lat: 45.46427, lon: 9.18951, hasResults: False
protocolSection identificationModule nctId: NCT06324110, orgStudyIdInfo id: RG1124119, secondaryIdInfos id: NCI-2024-01763, type: REGISTRY, domain: CTRP (Clinical Trial Reporting Program), secondaryIdInfos id: 20250, type: OTHER, domain: Fred Hutch/University of Washington Cancer Consortium, secondaryIdInfos id: R01CA284032, type: NIH, link: https://reporter.nih.gov/quickSearch/R01CA284032, briefTitle: Evaluating the Impact of Centralized Interventions on Lung Cancer Screening Adherence in Community Settings, ACCELL Trial, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-08-01, primaryCompletionDateStruct date: 2027-06-30, completionDateStruct date: 2027-06-30, studyFirstPostDateStruct date: 2024-03-21, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Fred Hutchinson Cancer Center, class: OTHER, collaborators name: National Cancer Institute (NCI), descriptionModule briefSummary: This clinical trial tests the impact of lung cancer screening care coordination interventions implemented at the system-level on lung cancer screening adherence in community settings. Lung cancer remains the leading cause of cancer death in the United States. Although lung cancer screening (LCS) with yearly low-dose chest computed tomography has the potential to decrease lung deaths, the use of this screening technique remains low. In addition, studies have shown that adherence to lung cancer screening in clinical settings is far lower that those found in clinical trials. Improved care coordination services that include comprehensive, system-wide tracking of screening outcomes for all LCS participants, results reporting with direct-to-patient information, direct patient and physician communication, and active reviews of non-adherent patients and stepped support interventions may increase patient adherence to LCS. Coordination services at the system-level may decrease barriers and improve adherence to lung cancer screening in community settings., conditionsModule conditions: Lung Carcinoma, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: SCREENING, maskingInfo masking: NONE, enrollmentInfo count: 8658, type: ESTIMATED, armsInterventionsModule interventions name: Electronic Health Record Review, interventions name: Interview, interventions name: Patient Navigation, outcomesModule primaryOutcomes measure: Adherence to appropriate follow-up, secondaryOutcomes measure: Characteristics associated with adherence to follow up, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Fred Hutch/University of Washington Cancer Consortium, city: Seattle, state: Washington, zip: 98109, country: United States, contacts name: Tinnie Louie, role: CONTACT, phone: 206-667-3323, email: tlouie@fredhutch.org, contacts name: Matthew Triplette, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 47.60621, lon: -122.33207, hasResults: False