protocolSection identificationModule nctId: NCT06287242, orgStudyIdInfo id: 24-01-282, briefTitle: Validation of the Cervicothoracic Differentiation Test, acronym: EMU, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-20, primaryCompletionDateStruct date: 2025-02, completionDateStruct date: 2025-02, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: University of Hartford, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to compare the effects of two spinal manipulations in adults between the ages of 18-65 based on the results of a non-invasive clinical test. The main question it aims to answer is: • Does matched or unmatched region of manipulation based on the CTDT result in greater reduction of pain levels and improvement in range of motion in adults with neck pain compared to unmatched manipulations? Participants will be asked to:* rate their pain with neck movement, complete brief questionnaires about their pain,* have their neck range of motion measured,* perform a test known as the cervico-thoracic differentiation test (CTDT),* receive either a cervical or thoracic manipulation,* repeat the range of motion measurements.* A second session will occur 7-10 days later where questionnaires and range of motion measures will be repeated.Researchers will compare the effects of manipulation matched to CTDT test result to individuals in the unmatched CTDT manipulation group to see if the CTDT may indicate which region will provide a greater treatment effect for individuals with neck pain., conditionsModule conditions: Neck Pain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, maskingDescription: Blinded research assistants will perform all baseline and follow-up measures. Investigator providing manipulation is blinded to group allocation (matched/unmatched) Participants will not be told if the CTDT indicates that they would benefit from cervical or thoracic manipulation, and the investigator performing the CTDT will only indicate which region is to be manipulated. All investigators are blinded to the work of the others and submit their results to an additional research assistant who will enter the data in a spreadsheet not accessible to the remainder of the research team until the conclusion of the study., whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: spinal manipulation, outcomesModule primaryOutcomes measure: pain with motion, secondaryOutcomes measure: pain at rest, secondaryOutcomes measure: range of motion, secondaryOutcomes measure: neck disability index, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Hartford, status: RECRUITING, city: West Hartford, state: Connecticut, zip: 06117, country: United States, contacts name: Brian Swanson, PT, DSc, role: CONTACT, phone: 860-768-5314, email: bswanson@hartford.edu, geoPoint lat: 41.76204, lon: -72.74204, hasResults: False