protocolSection identificationModule nctId: NCT06384716, orgStudyIdInfo id: CEB, briefTitle: Evaluation of the Influence of a Core Muscle Control-Based Rehabilitation Program Patients With Multiple Sclerosis, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-19, primaryCompletionDateStruct date: 2024-07-01, completionDateStruct date: 2024-09-01, studyFirstPostDateStruct date: 2024-04-25, lastUpdatePostDateStruct date: 2024-04-25, sponsorCollaboratorsModule leadSponsor name: Universidad Europea de Madrid, class: OTHER, descriptionModule briefSummary: Given the structural relationship of the CORE as a whole, in this study we propose an intervention based on the global motor control of all the structures that make up the CORE to assess its effectiveness on urinary incontinence, sexual dysfunction and balance, as well as its relationship with respiratory function. According to our hypothesis, a global intervention could also be taken into account during conventional treatment in the future, helping to prevent genitourinary dysfunctions derived from alterations in motor control., conditionsModule conditions: Multiple Sclerosis, conditions: Pelvic Floor Disorders, conditions: Incontinence, Urinary, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: This is a randomised clinical trial. The research will be conducted in accordance with the framework of application of the Helsinki declaration (21) and the law on Personal Data Protection and guarantee of digital rights (Organic Law 3/2018) . The design of this project will follow the definition of the standard elements of a clinical trial protocol: SPIRIT declaration, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: INVESTIGATOR, enrollmentInfo count: 32, type: ESTIMATED, armsInterventionsModule interventions name: rehabilitation programme based on motor control of core muscles, outcomesModule primaryOutcomes measure: Difference in the percentage of initial and final maximum activity of the pelvic floor muscles., primaryOutcomes measure: - Differences between the initial and final thickness of the oblique abdominis and transverse oblique muscles by ultrasound., primaryOutcomes measure: - Differences in the assessment of health-related quality of life before and after the intervention measured with the I-QOL questionnaire., primaryOutcomes measure: - Differences in the assessment of female UI before and after intervention using the I-CIQ questionnaire, secondaryOutcomes measure: - Difference in the percentage of initial and final maximum activity of the paravertebral musculature activity., secondaryOutcomes measure: - Differences between initial and final amplitude of initial and final diaphragmatic excursion by ultrasound., secondaryOutcomes measure: - Difference between initial and final FVC/- Differences between the initial and final peak expired volume (FEV1), secondaryOutcomes measure: differences between peak expiratory pressure (PEM) and minimum initial and end inspiratory pressure (MIP)., secondaryOutcomes measure: balance, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Cecilia Estrada Barranco, status: RECRUITING, city: Madrid, country: Spain, contacts name: Cecilia Estrada-Barranco, PhD, role: CONTACT, phone: 686166483, email: cecilia.estrada@universidadeuropea.es, contacts name: Esther Delgado, PhD, role: CONTACT, email: esther.delgado@universidadeuropea.es, geoPoint lat: 40.4165, lon: -3.70256, hasResults: False