hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06373393, orgStudyIdInfo id: 1, briefTitle: SPIRIT: Study of the Patency of Spinal aRteries After the STABILISE Technique, acronym: SPIRIT, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2024-04-16, primaryCompletionDateStruct date: 2024-07-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-04-18, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Associacao para Investigacao e Desenvolvimento da Faculdade de Medicina - CETERA, class: OTHER, collaborators name: Cardiovascular Center of the University of Lisbon, collaborators name: Unidade Local de Saúde Santa Maria, descriptionModule briefSummary: The aim of the study is to evaluate the impact of the stent-assisted balloon-induced intimal disruption and relamination in aortic dissection repair (STABILISE) technique in the patency of intercostal and lumbar arteries detectable on computed tomography angiography (CTA) in patients with type B aortic dissection and its correlation with the occurrence of spinal cord ischaemia (SCI).Primary end-point: patency of the intercostal and lumbar arteries on follow-up CTA.Secondary end-point: spinal cord ischaemia, conditionsModule conditions: Aortic Dissection, conditions: Spinal Cord Ischemia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: STABILISE, outcomesModule primaryOutcomes measure: number of patent intercostal and lumbar arteries, secondaryOutcomes measure: number of patients with spinal cord ischemia, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 100 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Unidade Local de Saúde Santa Maria, city: Lisbon, zip: 1500, country: Portugal, geoPoint lat: 38.71667, lon: -9.13333, hasResults: False
protocolSection identificationModule nctId: NCT06373367, orgStudyIdInfo id: 461-24, briefTitle: Preeclampsia Educational Program Study (PrEPS), acronym: PrEPS, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2024-11-01, completionDateStruct date: 2024-11-01, studyFirstPostDateStruct date: 2024-04-18, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: MemorialCare Health System, class: OTHER, descriptionModule briefSummary: Preeclampsia complicates approximately 8% of all pregnancies. A critical factor of outpatient monitoring is patient education; specifically, education regarding nature of the disease, ongoing short- and long-term risks, and warning signs and symptoms for worsening of disease. This study aims to compare patient knowledge using a novel illustration based app compared to standard discharge instructions., conditionsModule conditions: Preeclampsia, conditions: Preeclampsia Severe, conditions: Preeclampsia Mild, conditions: Preeclampsia Postpartum, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 36, type: ESTIMATED, armsInterventionsModule interventions name: Illustration based application, interventions name: Text based application, outcomesModule primaryOutcomes measure: Preeclampsia knowledge score - short, secondaryOutcomes measure: Preeclampsia knowledge score - long, secondaryOutcomes measure: GAD-7 score, secondaryOutcomes measure: 72 hour BP check, secondaryOutcomes measure: Postpartum visit, secondaryOutcomes measure: Daily BP recordings, secondaryOutcomes measure: Accessed material, secondaryOutcomes measure: Unplanned readmission, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06373354, orgStudyIdInfo id: 2023-0924, secondaryIdInfos id: NCI-2024-03341, type: OTHER, domain: NCI-CTRP Clinical Registry, briefTitle: Comparison of Conspicuity of Masses and Architectural Distortions Between Wide- and Narrow-angle Digital Breast Tomosynthesis Systems, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09-30, primaryCompletionDateStruct date: 2025-12-31, completionDateStruct date: 2027-12-31, studyFirstPostDateStruct date: 2024-04-18, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: M.D. Anderson Cancer Center, class: OTHER, collaborators name: Siemens Medical Solutions, descriptionModule briefSummary: To compare narrow-angle digital breast tomosynthesis (DBT) and wide-angle DBT., conditionsModule conditions: Architectural Distortions, conditions: Breast Tomosynthesis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Digital Breast Tomosynthesis (DBT), outcomesModule primaryOutcomes measure: Safety and adverse events (AEs), eligibilityModule sex: FEMALE, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: MD Anderson Cancer Center, city: Houston, state: Texas, zip: 77030, country: United States, contacts name: Tanya Moseley, MD, role: CONTACT, phone: 713-792-5755, email: tstephens@mdanderson.org, contacts name: Tanya Moseley, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 29.76328, lon: -95.36327, hasResults: False
protocolSection identificationModule nctId: NCT06373341, orgStudyIdInfo id: NL85317.099.23, briefTitle: Hand and Arm Rehabilitation Using VR, acronym: HANDQUEST, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-15, primaryCompletionDateStruct date: 2026-01, completionDateStruct date: 2027-01, studyFirstPostDateStruct date: 2024-04-18, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: Medical Centre Leeuwarden, class: OTHER, descriptionModule briefSummary: Patients admitted to the ICU due to critical illness often experience physical, mental, cognitive, or social issues. Research indicates that inadequate physical recovery is associated with lower handgrip strength, and hand function in ICU patients is lower compared to healthy individuals. To address this, a Virtual Reality (VR) exergame was developed to aid rehabilitation. This study aims to investigate the effect of a 4-week VR-exergame intervention on handgrip strength, hand and arm functionality, balance, mobility, and support needs in ICU patients staying for 48 hours or longer. It is a multicenter mixed-methods randomized controlled trial involving adult ICU patients. The intervention involves a 4-week VR-exergame program. Main study parameters include handgrip strength, hand and arm functionality, range of motion, balance, mobility, and support needs. The burden and risks associated with participation are minimal, as VR-based exercises are deemed safe and voluntary. Overall, the study aims to assess the effect of incorporating VR-based rehabilitation into standard care for ICU patients., conditionsModule conditions: Post-Intensive Care Syndrome, conditions: ICU Acquired Weakness, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 108, type: ESTIMATED, armsInterventionsModule interventions name: VR training for arm and hand rehabilitation, outcomesModule primaryOutcomes measure: Handgrip strength, secondaryOutcomes measure: Handgrip strength, secondaryOutcomes measure: Arm and hand functionality, secondaryOutcomes measure: Arm and hand functionality, secondaryOutcomes measure: Arm and hand range of motion, secondaryOutcomes measure: Balance and mobility, secondaryOutcomes measure: Support need and experience with VR training, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Dept of intensive care, Medical Centre Leeuwarden, status: RECRUITING, city: Leeuwarden, state: Friesland, zip: 8901 BR, country: Netherlands, contacts name: Lise Beumeler, PhD, role: CONTACT, phone: (058) 286 6738, email: lise.beumeler@mcl.nl, contacts name: Lise Beumeler, PhD, role: PRINCIPAL_INVESTIGATOR, contacts name: Carina Bethlehem, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 53.20139, lon: 5.80859, hasResults: False
protocolSection identificationModule nctId: NCT06373328, orgStudyIdInfo id: STUDY00006081, briefTitle: Post Pandemic Pneumococcal Carriage Among Children and Adults, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2025-09, completionDateStruct date: 2026-03, studyFirstPostDateStruct date: 2024-04-18, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: University of Central Florida, class: OTHER, collaborators name: Merck Sharp & Dohme Corporation, descriptionModule briefSummary: The PI propose to conduct a genomic epidemiology study of pneumococcal carriage among children and adults in a large metropolitan city. These data will allow PI to assess the post-pandemic population structure, investigate the phylogenetic relationship between isolates from children and adults, and compare pneumococcal populations across diverse geographic areas., conditionsModule conditions: Pneumococcal Carriage, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 900, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Pneumococcal carriage prevalence and distribution of serotypes among children and adults calculated from the results of S. pneumoniae isolation using qPCR., secondaryOutcomes measure: Phylogenetic relationship of pneumococcal isolates collected among child and adult populations using whole-genome sequencing libraries., secondaryOutcomes measure: Putative transmission networks between children and adult populations from online questionnaires., eligibilityModule sex: ALL, minimumAge: 7 Months, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06373315, orgStudyIdInfo id: 2023/11-18, briefTitle: The Effect of Smartphone and Hand Anthropometry on Pain and Upper Extremity Functions, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-02, primaryCompletionDateStruct date: 2024-06-30, completionDateStruct date: 2025-05-02, studyFirstPostDateStruct date: 2024-04-18, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: Nigde Omer Halisdemir University, class: OTHER, descriptionModule briefSummary: Mobile phones have different uses in different disciplines, and this encourages long-term use. For optimum comfort use, it is important to ensure users' awareness when purchasing mobile phones that match their hand sizes. The number of studies in the literature on this subject is limited. In this context, the aim of our study is to investigate the relationship between smartphone and hand anthropometry measurements and upper extremity pain and functions., conditionsModule conditions: Upper Extremity Problem, conditions: Smartphone Addiction, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 90, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Hand anthropometric measurements: Hand length, primaryOutcomes measure: Hand anthropometric measurements: Palm length, primaryOutcomes measure: Hand anthropometric measurements: Width of the hand (Metacarpal), primaryOutcomes measure: Hand anthropometric measurements: Maximum hand spread measurement, primaryOutcomes measure: Gross grip strength measurement, primaryOutcomes measure: Pinch grip strength, primaryOutcomes measure: Measurement of phone dimensions, primaryOutcomes measure: Upper extremity functional status assessment, secondaryOutcomes measure: Pain assessment, secondaryOutcomes measure: Smartphone addiction, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Nigde Omer Halisdemir University, Bor Faculty of Health Sciences, city: Niğde, state: Nigde, zip: 51700, country: Turkey, contacts name: Feyza Altindal Karabulut, Assoc. Prof., role: CONTACT, phone: +905056263833, email: fztfyz@gmail.com, geoPoint lat: 37.96583, lon: 34.67935, hasResults: False
protocolSection identificationModule nctId: NCT06373302, orgStudyIdInfo id: IRAS 323948, briefTitle: Peripheral Arterial Disease Biomarkers, acronym: PADBIRD, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2026-12-31, studyFirstPostDateStruct date: 2024-04-18, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: Norfolk and Norwich University Hospitals NHS Foundation Trust, class: OTHER, descriptionModule briefSummary: The study aims to determine how expression levels of biomarkers for peripheral arterial disease change over time in response to exercise therapy, surgical or endovascular intervention, and whether they can be used to predict disease progression., conditionsModule conditions: Peripheral Arterial Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: OTHER, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Correlation between PAD biomarker levels and walking distance., primaryOutcomes measure: Change in PAD biomarker levels following exercise therapy., primaryOutcomes measure: Change in PAD biomarker levels following endovascular intervention, secondaryOutcomes measure: To determine whether biomarker levels normalise with improved walking distance., secondaryOutcomes measure: To determine whether biomarker levels can be used as a predictor of restenosis, occlusion or reintervention following endovascular intervention., secondaryOutcomes measure: Levels of biomarkers and (Major Adverse Cardiovascular Events)., eligibilityModule sex: ALL, minimumAge: 50 Years, maximumAge: 99 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06373289, orgStudyIdInfo id: 000539476, secondaryIdInfos id: 1K23HD113837-01A1, type: OTHER, domain: NICHD (pending), briefTitle: Target Oxygen Ranges in Infants With Pulmonary Hypertension, acronym: TORPH, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2025-07-01, primaryCompletionDateStruct date: 2029-07-01, completionDateStruct date: 2030-07-01, studyFirstPostDateStruct date: 2024-04-18, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: University of Alabama at Birmingham, class: OTHER, descriptionModule briefSummary: Around 50% of infants born extremely preterm develop a chronic lung disease known as bronchopulmonary dysplasia of which some infants will also develop pulmonary hypertension of which 50% of children will die before the age of 2. Physicians are currently limited in their ability to select the most appropriate oxygen targets that will improve outcomes in infants with this condition. This clinical trial will determine whether using different amounts of oxygen improve outcomes in infants with this disease., conditionsModule conditions: Bronchopulmonary Dysplasia, conditions: Pulmonary Hypertension, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: Single center, randomized cross-over pilot study with a 1:1 parallel allocation of infants to SpO2 targets of 92-95% (control) and 95-98% (intervention) using a stratified permuted block design. Following 2 weeks of exposure A, infants will cross over to exposure B for 2 weeks with a 1-week washout period., primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: The PI will perform bedside echocardiography precluding masking to group allocation. All echocardiograms will be further reviewed by a cardiologist masked to group allocation with additional cardiologist review in instances of disagreement. Inter-rater reliability testing will also be performed., whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 39, type: ESTIMATED, armsInterventionsModule interventions name: higher oxygen saturation target using Nellcor pulse oximetry sensors, interventions name: lower oxygen saturation target using Nellcor pulse oximetry sensors, outcomesModule primaryOutcomes measure: Intermittent hypoxemia event duration, secondaryOutcomes measure: Echocardiographic shunting, secondaryOutcomes measure: Echocardiographic interventricular septal flattening, secondaryOutcomes measure: Echocardiographic tricuspid regurgitation, secondaryOutcomes measure: Intermittent hypoxemia frequency, secondaryOutcomes measure: Cumulative hypoxemia, secondaryOutcomes measure: Brain natriuretic peptide, eligibilityModule sex: ALL, minimumAge: 2 Months, maximumAge: 5 Months, stdAges: CHILD, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06373263, orgStudyIdInfo id: 2024-4165, briefTitle: Evaluating Tools to Communicate Scleroderma Research Results to Patients, acronym: SPIN-KT, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06, primaryCompletionDateStruct date: 2024-06, completionDateStruct date: 2024-06, studyFirstPostDateStruct date: 2024-04-18, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: Lady Davis Institute, class: OTHER, descriptionModule briefSummary: Sharing research results with patients is required by ethical regulations. Yet, most researchers do not share results from their studies with patients. The investigators plan to conduct a series of randomized controlled trials among people with scleroderma, a rare autoimmune disease, in a large international cohort, to identify the most effective methods for communicating study results with patients.The first trial in the series will compare a research dissemination tool (infographic) against a plain-language summary comparator. Participants will be randomly assigned to receive the dissemination tool or comparator. Study participants will rate communication tools for (1) information completeness; (2) understandability; and (3) ease of use of format. Our results can be used by researchers and patient organizations who disseminate research results so that they can tailor the way they disseminate results to patient needs., conditionsModule conditions: Scleroderma, conditions: Systemic Sclerosis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Parallel Assignment, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 488, type: ESTIMATED, armsInterventionsModule interventions name: Plain-language summary, interventions name: Dissemination Tool (Infographic), outcomesModule primaryOutcomes measure: Completeness, primaryOutcomes measure: Understandability, primaryOutcomes measure: Ease of use, secondaryOutcomes measure: Please to have received results, secondaryOutcomes measure: Intention to participate in future studies, secondaryOutcomes measure: Open-ended items, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06373250, orgStudyIdInfo id: sdilek7, briefTitle: Maternal Consequences of Membrane Stripping, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-11, primaryCompletionDateStruct date: 2024-10-11, completionDateStruct date: 2024-11-11, studyFirstPostDateStruct date: 2024-04-18, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: Kocaeli University, class: OTHER, descriptionModule briefSummary: This study aims to investigate the maternal effects of membrane stripping during vaginal birth. This study was designed as an experimental case-control study. The sample size in the study was determined by Njoku et al in 2023 to assess the effectiveness of membrane stripping applied to participants who had vaginal birth in reducing the incidence of prolonged pregnancy. Calculated based on the study conducted by. The sample size of the study was calculated using G\*Power 3.1.9.2, and the mean and standard deviation of the Bishop score in the relevant article were used to calculate the effect size. Using the mean and standard deviation of the relevant article, the blended effect size was calculated as 0.596. The minimum number of individuals that should be included in the sample of this research was calculated using G\*Power 3.1.9.2, effect size: 0.596, α= 0.05, power: 0.95 (stripping = 70, control = 70) and at least in each group in the sample size. The sample size was set at 70 participants. The research data will be collected by the researcher using the Informed Volunteer Consent Form, Participant Information Form, Bishop Scoring, Visual Analogue Scale, and Birth Satisfaction Scale Short Form, which were created by the researcher within the framework of the literature on the subject., conditionsModule conditions: Maternal Care for Other Abnormalities of Cervix, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 140, type: ESTIMATED, armsInterventionsModule interventions name: Membrane stripping group, interventions name: Control group, outcomesModule primaryOutcomes measure: Visual analogue scale evaluation of vaginal examination pain, primaryOutcomes measure: Visual analogue scale evaluation of vaginal examination pain, primaryOutcomes measure: Evaluation of the cervix with Bishop score, primaryOutcomes measure: Evaluation of the amount of bleeding, primaryOutcomes measure: Birth Satisfaction Scale Short Form, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Kocaeli University, status: RECRUITING, city: Kocaeli, zip: 41380, country: Turkey, contacts name: Burcu Ozturk, M.Sc., role: CONTACT, email: 1burcuozturk@gmail.com, geoPoint lat: 39.62497, lon: 27.51145, hasResults: False
protocolSection identificationModule nctId: NCT06373237, orgStudyIdInfo id: INC-IG-2024-001, briefTitle: Outcome of Embryos Transferred After Initial Chaotic Results on PGT-A, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-03-26, primaryCompletionDateStruct date: 2024-05, completionDateStruct date: 2026-05, studyFirstPostDateStruct date: 2024-04-18, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: Inception Fertility, LLC, class: INDUSTRY, collaborators name: Igenomix, descriptionModule briefSummary: This is a retrospective review of treatment outcomes from fertility clinics in The Prelude Network who have used Igenomix for PGT-A and have transferred embryos with initial chaotic results, regardless if re-biopsy was performed., conditionsModule conditions: Infertility, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 2000, type: ESTIMATED, outcomesModule primaryOutcomes measure: Frequency of embryo re-biopsy, primaryOutcomes measure: Re-biopsy results, primaryOutcomes measure: Embryo disposition, primaryOutcomes measure: Embryo transfer outcome, primaryOutcomes measure: Pregnancy outcome, eligibilityModule sex: FEMALE, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Inception Fertility LLC, city: Houston, state: Texas, zip: 77081, country: United States, geoPoint lat: 29.76328, lon: -95.36327, hasResults: False