hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06333847, orgStudyIdInfo id: K2023-059, briefTitle: Is Multimorbidity a Source of Non-response Bias in Patients With Spinal Pain? - A Pilot Study, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2023-06-01, primaryCompletionDateStruct date: 2024-04-20, completionDateStruct date: 2024-04-20, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Jacob Christiansen Gandløse, class: OTHER, collaborators name: Aalborg Municipality, collaborators name: Aalborg University, collaborators name: Aalborg University Hospital, descriptionModule briefSummary: The purpose of this study is to investigate whether the number of chronic diseases, the treatment burden resulting from multimorbidity, and health-related quality of life contribute to non-response bias in individuals with chronic back pain. Data is collected from patients at Aalborg University Hospital's Rheumatology Department through electronic means and medical records. The statistical analyses consist of two wave analyses, where we examine differences between patients who respond to invitations to participate in the study based on their response patterns; whether they respond after the first, second, or third invitation. Based on baseline data, a one-way ANOVA is conducted to identify any between-group differences in the aforementioned factors, followed by a repeated measures ANOVA to assess if there are differences between the groups over time. Finally, statistical tests are also performed to examine differences in age and gender distribution between those who complete the questionnaires at baseline compared to those who do not respond to the invitation to participate., conditionsModule conditions: Back Pain, conditions: Low Back Pain, conditions: Neck Pain, conditions: Comorbidities and Coexisting Conditions, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 400, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Multimorbidity Treatment Burden Questionnaire (MTBQ)., secondaryOutcomes measure: Health-related quality of life (EQ-5D-5L), otherOutcomes measure: Brief Pain Inventory - Short form, otherOutcomes measure: Insomnia Severity Index, otherOutcomes measure: Patient Health Questionnaire, otherOutcomes measure: Generalized Anxiety Disorder, otherOutcomes measure: Work ability score, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Aalborg University Hospital, city: Aalborg, zip: 9000, country: Denmark, geoPoint lat: 57.048, lon: 9.9187, hasResults: False
protocolSection identificationModule nctId: NCT06333769, orgStudyIdInfo id: CATIMOR, briefTitle: A Phase II Multicenter Clinical Study of Improved Short-course Radiotherapy Combined With CAPOX and PD-1 Monoclonal Antibody for Locally Advanced Mid-low Rectal Cancer, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2025-12-01, completionDateStruct date: 2026-12-01, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Fujian Cancer Hospital, class: OTHER_GOV, descriptionModule briefSummary: To explore the complete response (CR) rate of improved short-course radiotherapy combined with CAPOX and tislelizumab for locally Advanced Mid-low Rectal Cancer, conditionsModule conditions: Mid-low Rectal Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 31, type: ESTIMATED, armsInterventionsModule interventions name: Short-course Radiotherapy, interventions name: Tislelizumab, interventions name: capecitabine, interventions name: Oxaliplatin, outcomesModule primaryOutcomes measure: complete response (CR) rate, secondaryOutcomes measure: 3y-DFS, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06333756, orgStudyIdInfo id: YM110099E, briefTitle: Effects of Muscle Strengthening and Fatigue on Activities in Cortex and Muscle, acronym: YM110099E, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-05-01, primaryCompletionDateStruct date: 2022-04-30, completionDateStruct date: 2022-08-01, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: National Yang Ming University, class: OTHER, descriptionModule briefSummary: We will explored the effect of cross education training on different cortex functional connectivity, cortex and muscle functional connectivity, and maximal voluntary contraction.Healthy participants receive cross education training of the elbow flexor (12 rep./set, 3sets, 60%MVC, 180°/s, eccentric).Maximal voluntary contraction, electroencephalogram and electromyogram will record during cross education tasks to determine the effects of cross education training on cortical network and muscle functional connectivity, conditionsModule conditions: Healthy Adults, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: Parallel Assignment, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ACTUAL, armsInterventionsModule interventions name: Cross education, outcomesModule primaryOutcomes measure: Corticocortical coherence, primaryOutcomes measure: Corticomuscular coherence, primaryOutcomes measure: Maximal voluntary contraction, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: National Yang-Ming University, city: Taipei, zip: 112, country: Taiwan, geoPoint lat: 25.04776, lon: 121.53185, hasResults: False
protocolSection identificationModule nctId: NCT06333743, orgStudyIdInfo id: ZhuLan, briefTitle: Laser Ablation in the Treatment of High-grade Cervical Lesions, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2025-12, completionDateStruct date: 2026-05, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Peking Union Medical College Hospital, class: OTHER, collaborators name: Obstetrics & Gynecology Hospital of Fudan University, descriptionModule briefSummary: Cervical laser ablation is an effective, minimally invasive treatment with a low incidence of perinatal complications and minimal impact on fertility. Research has confirmed that laser ablation treatment of cervical HSIL (including CIN2 and CIN3) is effective and feasible and is useful for young CIN3 patients who wish to get pregnant in the future. There have been no randomized clinical trials of laser ablation therapy for cervical HSIL in Chinese women. This study focuses on the application of laser ablation in the treatment of cervical HSIL, explores the efficacy, feasibility, and safety of laser ablation in the treatment of cervical HSIL, and strives to promote the reasonable application of laser ablation in the treatment of cervical HSIL., conditionsModule conditions: High-Grade Squamous Intraepithelial Lesions, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 308, type: ESTIMATED, armsInterventionsModule interventions name: laser ablation, interventions name: LEEP or Conization, outcomesModule primaryOutcomes measure: the rate of HSIL recurrence, secondaryOutcomes measure: the satisfaction with the treatment, secondaryOutcomes measure: the length of the cervix, secondaryOutcomes measure: Psychological state change related to the treatment, eligibilityModule sex: FEMALE, maximumAge: 40 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06333730, orgStudyIdInfo id: PMC, briefTitle: Comparison of Anesthetic Efficacy of Mental Nerve Block Versus Inferior Alveolar Nerve Block in Mandibular Anterior Teeth and Premolars in Symptomatic Irreversible Pulpitis, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-05-30, completionDateStruct date: 2024-06-20, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Prime Foundation, class: OTHER, descriptionModule briefSummary: Symptomatic irreversible pulpitis is a painful condition that requires anesthesia to perform effective dental procedures. The mental nerve block and inferior alveolar nerve block are two commonly used techniques for achieving anesthesia in the mandibular teeth.Study design: This randomized clinical trial study Number of participants: 96 participants which will be randomly divided into two groups: MINB and IANB.Inclusion criteria: Participants with mandibular premolars or lower anterior experiencing sharp and persistent pain in response to thermal stimuli and an electric pulp tester, as well as bleeding during access opening, will be included.Exclusion criteria: Participants with a medical history, allergies or contraindications to the local anesthetic, pregnant or breastfeeding women, those taking pain-affecting medication, or those experiencing pain in more than one tooth will be excluded.Both techniques will use 2% lidocaine and adrenaline 1:80,000. Age, gender, and the efficacy of anesthesia will be recorded in both groups. The chi-square test will be used for comparison., conditionsModule conditions: Symptomatic Irreversible Pulpitis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 96, type: ESTIMATED, armsInterventionsModule interventions name: inferior alveolar nerve block, interventions name: mental nerve block, outcomesModule primaryOutcomes measure: COMPARISON OF ANESTHETIC EFFICACY OF MENTAL NERVE BLOCK VERSUS INFERIOR ALVEOLAR NERVE BLOCK IN MANDIBULAR ANTERIORS TEETH AND PREMOLARS IN SYMPTOMATIC IRREVERSIBLE PULPITIS, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Peshawar Dental College, status: RECRUITING, city: Peshawar, state: Khyber Pakhtunkhwa, zip: 25000, country: Pakistan, contacts name: Prof. Dr. Iftikhar Akbar, FCPS, CHIPE, role: CONTACT, phone: 00923479368676, email: driftikhar156@hotmail.com, contacts name: Marghalara Noor, BDS, role: CONTACT, phone: 00923359631393, email: marghalaranoor96@gmail.com, contacts name: Saifa Rashad, BDS, role: SUB_INVESTIGATOR, geoPoint lat: 34.008, lon: 71.57849, hasResults: False
protocolSection identificationModule nctId: NCT06333691, orgStudyIdInfo id: Aya Mohammed, briefTitle: Comparative Study Between Calcium Gluconate With Diosmin, Cabergoline and Cabergoline With Diosmin, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-10-01, primaryCompletionDateStruct date: 2024-02-01, completionDateStruct date: 2024-02-15, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Minia University, class: OTHER, descriptionModule briefSummary: Ovarian hyperstimulation syndrome is a potentially fatal iatrogenic condition. This syndrome is characterized by a sudden increase of the vascular permeability which results in the development of a massive extravascular exudate in the peritoneal cavity, pleural, pericardium causing ascites, pleural and pericardial effusion.Severe forms are also accompanied by electrolyte disturbances and cardiopulmonary, hepatic, renal, and hemoconcentration associated with increased thromboembolic risk.This syndrome is avoidable by the judicious use of gonadotropins and careful monitoring of stimulation regimens., conditionsModule conditions: Ovarian Hyperstimulation Syndrome, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 180, type: ACTUAL, armsInterventionsModule interventions name: Calcium Gluconate, outcomesModule primaryOutcomes measure: the incidence rate of moderate to severe OHSS., eligibilityModule sex: FEMALE, minimumAge: 23 Years, maximumAge: 39 Years, stdAges: ADULT, contactsLocationsModule locations facility: Minia University, Faculty of Pharmacy, city: Minya, country: Egypt, geoPoint lat: 28.10988, lon: 30.7503, hasResults: False
protocolSection identificationModule nctId: NCT06333665, orgStudyIdInfo id: Wei G, briefTitle: PPIO-007 Correlation Analysis of Type II Diabetes Mellitus on Short-term and Long-term Outcomes of Patients With Esophageal Squamous Cell Cancer Undergoing Minimally Invasive Esophagectomy, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-02-20, primaryCompletionDateStruct date: 2024-04-20, completionDateStruct date: 2024-05-20, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, class: OTHER, descriptionModule briefSummary: To date, there is controversy as to whether type II diabetes mellitus is associated with adverse short- and long-term outcomes in patients with esophageal squamous cell carcinoma undergoing minimally invasive esophagectomy. At the same time, to the best of our knowledge, the impact of metformin use and glycemic control on short- and long-term outcomes in this patient population is also controversial. Therefore, this study aims to test the hypothesis that diabetes mellitus is associated with reduced survival in patients with esophageal squamous cell carcinoma undergoing minimally invasive esophagectomy and that treatment with metformin and/or good glycemic control (HbA1c\<7.0%) is associated with improved survival., conditionsModule conditions: Esophageal Squamous Cell Carcinoma, conditions: Surgery, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 605, type: ACTUAL, armsInterventionsModule interventions name: Whether there is type 2 diabetes mellitus before surgery, outcomesModule primaryOutcomes measure: Overall survival, primaryOutcomes measure: Disease-free survival, secondaryOutcomes measure: postoperative adverse events, secondaryOutcomes measure: perioperative 90-day mortality, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Army Medical Center of the People's Liberation Army, city: Chongqing, state: Chongqing, zip: 400042, country: China, geoPoint lat: 29.56278, lon: 106.55278, hasResults: False
protocolSection identificationModule nctId: NCT06333652, orgStudyIdInfo id: 22-009239, briefTitle: Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2026-12-31, completionDateStruct date: 2028-12-31, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Mayo Clinic, class: OTHER, descriptionModule briefSummary: The researchers are testing a medication named ravulizumab for the treatment of severe preeclampsia and Hemolysis, Elevated Liver enzymes, Low Platelets (HELLP) syndrome., conditionsModule conditions: Preeclampsia, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 14, type: ESTIMATED, armsInterventionsModule interventions name: Ravulizumab, outcomesModule primaryOutcomes measure: Alternative Complement Pathway Biomarkers at time of delivery, secondaryOutcomes measure: Pregnancy duration, secondaryOutcomes measure: Clinical biomarkers of severe features of preeclampsia and HELLP syndrome, secondaryOutcomes measure: Hospitalization length in the postpartum period, secondaryOutcomes measure: Meningococcal infection after use of ravulizumab, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule locations facility: Mayo Clinic Minnesota, status: RECRUITING, city: Rochester, state: Minnesota, zip: 55905, country: United States, contacts name: Maria L. Gonzalez Suarez, MD,PhD, role: CONTACT, phone: 507-284-4083, email: gonzalezsuarez.maria@mayo.edu, geoPoint lat: 44.02163, lon: -92.4699, hasResults: False
protocolSection identificationModule nctId: NCT06333639, orgStudyIdInfo id: 24Chirortho01, briefTitle: Implementing Virtual Reality in the Operating Room, acronym: IRVABO, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-10-15, completionDateStruct date: 2024-10-15, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Centre Hospitalier Universitaire de Nice, class: OTHER, descriptionModule briefSummary: "Recently, virtual reality has become more accessible thanks to the use of smaller, more comfortable and easier-to-use devices. Its use in operating theatres is growing.However, despite the clinical effectiveness of virtual reality in reducing pain and anxiety, there are very few feedback studies from patients on their experience of surgery and their satisfaction, especially in orthopaedics.The aim of this study is to demonstrate the superiority, during long awake orthopaedic surgery, of equipping the patient with a virtual reality headset, on patient satisfaction, compared with the same surgery without a headset.The visual support offered will be appropriate to the duration of the surgery, i.e. more than 1 hour.", conditionsModule conditions: General Surgery, conditions: Orthopedic Procedures, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: orthopaedic surgery, interventions name: orthopaedic surgery and fitted with a virtual reality headset, outcomesModule primaryOutcomes measure: To demonstrate the superiority, during long awake orthopaedic surgery, of equipping the patient with a virtual reality headset, on patient satisfaction, compared with the same surgery without a headset., secondaryOutcomes measure: 1. To demonstrate the superiority, during long awake orthopaedic surgery, of equipping the patient with a virtual reality headset, on the doses of premedication, compared with the same surgeries without headset., secondaryOutcomes measure: Evaluate the Virtual Reality device in terms of comfort when wearing the headset, visual comfort and image and scenario quality, and auditory quality, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: CHU NiICE, city: Nice, state: Alpes Maritimes, zip: 0600, country: France, contacts name: GAUCI Marc-Olivier, role: CONTACT, phone: 04 92 03 69 04, phoneExt: +33, email: gauci.mo@chu-nice.fr, geoPoint lat: 43.70313, lon: 7.26608, hasResults: False
protocolSection identificationModule nctId: NCT06333626, orgStudyIdInfo id: 2020281, briefTitle: Effects of an Oral Multi-vitamin Carbohydrate Beverage on Intraoperative Nausea and Vomiting, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-03-31, completionDateStruct date: 2025-03-31, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: The First Affiliated Hospital of Soochow University, class: OTHER, descriptionModule briefSummary: Nausea and vomiting are common and unpleasant symptoms for pregnant women during cesarean section, which can lead to aspiration, a serious complication that can cause pneumonia. Our study aimed to evaluate the effects of oral multi-vitamin carbohydrate beverage on maternal intraoperative nausea and vomiting by gastric ultrasound., conditionsModule conditions: Nausea and Vomiting, Aspiration, Intraoperative, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 90, type: ESTIMATED, armsInterventionsModule interventions name: multi-vitamin carbohydrate, outcomesModule primaryOutcomes measure: Gastric antrum area, secondaryOutcomes measure: vomiting, secondaryOutcomes measure: The pH of vomiting fluid, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06333613, orgStudyIdInfo id: CR-6565, briefTitle: Evaluation of Acuvue Oasys 1-Day Contact Lenses in New Wearers, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-26, primaryCompletionDateStruct date: 2024-05-20, completionDateStruct date: 2024-05-20, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Johnson & Johnson Vision Care, Inc., class: INDUSTRY, descriptionModule briefSummary: This is a multi-site, bilateral, dispensing, non-randomized, uncontrolled, unmasked, single arm study to evaluate visual acuity in neophytes., conditionsModule conditions: Visual Acuity, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: ACUVUE OASYS® 1-DAY with HydraLuxe™ TECHNOLOGY (AO1D), outcomesModule primaryOutcomes measure: Percentage of eyes with slit-lamp findings (Grade 3 or 4) related to study lens wear, eligibilityModule sex: ALL, minimumAge: 13 Years, maximumAge: 39 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Scripps Poway Eyecare & Optometry, status: RECRUITING, city: San Diego, state: California, zip: 92131, country: United States, geoPoint lat: 32.71533, lon: -117.15726, locations facility: Omega Vision Center, status: RECRUITING, city: Longwood, state: Florida, zip: 32779, country: United States, geoPoint lat: 28.70305, lon: -81.3384, locations facility: Maitland Vision Center - North Orlando Ave, status: RECRUITING, city: Maitland, state: Florida, zip: 32751, country: United States, geoPoint lat: 28.62778, lon: -81.36312, locations facility: Kannarr Eye Care, status: RECRUITING, city: Pittsburg, state: Kansas, zip: 66762, country: United States, geoPoint lat: 37.41088, lon: -94.70496, locations facility: Procare Vision Centers, status: RECRUITING, city: Granville, state: Ohio, zip: 43023, country: United States, geoPoint lat: 40.06812, lon: -82.5196, hasResults: False