hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06363357, orgStudyIdInfo id: 24B-007-0000, briefTitle: The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Duchenne Muscular Dystrophy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-20, primaryCompletionDateStruct date: 2025-12-31, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-04-12, lastUpdatePostDateStruct date: 2024-04-12, sponsorCollaboratorsModule leadSponsor name: Seoul National University Hospital, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to investigate the effect of a muscle-mimicking, fabric-type shoulder orthosis on functional movements of the upper limb in patients with Duchenne muscular dystrophy.The main questions it aims to answer are:* What is the impact of the muscle-mimicking, fabric-type shoulder orthosis on upper limb functional movements in patients with Duchenne muscular dystrophy?* Are there observable differences in upper limb function when the shoulder orthosis is worn versus when it is not?Participants will:* Receive education on how to wear and use the shoulder orthosis.* Undergo evaluations, including assessment of upper limb performance, shoulder muscle strength testing, active range of motion measurements, assessment of functional workspace, goal attainment scale evaluation, surface electromyography, physiological measurements such as blood pressure and heart rate, fatigue assessment, and assessment for any musculoskeletal or skin-related issues.Researchers will compare Duchenne muscular dystrophy patients before and while wearing and operating the shoulder orthosis to see if there are any significant effects on variables such as upper limb function, range of motion, functional workspace, goal attainment scale, and surface electromyography., conditionsModule conditions: Muscular Dystrophy, Duchenne, conditions: Orthotic Devices, conditions: Upper Extremity, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: This study compares variables before and after wearing the shoulder orthosis in patients with Duchenne muscular dystrophy., primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Shoulder orthosis, outcomesModule primaryOutcomes measure: Performance of the upper limb module 2.0 (PUL 2.0), primaryOutcomes measure: Active Range of motion, primaryOutcomes measure: Functional workspace, primaryOutcomes measure: Goal Attainment Scale (GAS), primaryOutcomes measure: Surface electromyography (sEMG), eligibilityModule sex: ALL, minimumAge: 10 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Seoul National University Hospital, city: Seoul, state: Jongno-gu, zip: 03080, country: Korea, Republic of, contacts name: Woo Hyung Lee, MD, Ph.D, role: CONTACT, phone: +82-2-2072-4178, email: whlee909@snu.ac.kr, geoPoint lat: 37.566, lon: 126.9784, hasResults: False
protocolSection identificationModule nctId: NCT06363318, orgStudyIdInfo id: 0003, briefTitle: Comparison of Open and Laparoscopic Appendectomy in Pediatric Population, acronym: Appendicitis, statusModule overallStatus: COMPLETED, startDateStruct date: 2019-07-01, primaryCompletionDateStruct date: 2019-11-30, completionDateStruct date: 2019-11-30, studyFirstPostDateStruct date: 2024-04-12, lastUpdatePostDateStruct date: 2024-04-15, sponsorCollaboratorsModule leadSponsor name: King Edward Medical University, class: OTHER, descriptionModule briefSummary: Introduction: In the era of minimally invasive surgery, changing trends are towards laparoscopic surgery, first introduced in 1983. Now the preferred operation for children with appendicitis, laparoscopic appendectomy is associated with a reduced risk of wound infection, less postoperative pain and shorter hospital stay as compared to open appendectomy.Objectives: To compare the outcome of open and laparoscopic appendectomy in children presenting with appendicitis in terms of operative time, postoperative pain, wound infection and hospital stay., conditionsModule conditions: Appendicitis Acute, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: children were randomly divided in two groups. In group A, laparoscopic appendectomy was done. In group B, open appendectomy was done, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ACTUAL, armsInterventionsModule interventions name: Laparoscopic appendicectomy, outcomesModule primaryOutcomes measure: Operative time, primaryOutcomes measure: wound infection, primaryOutcomes measure: Hospital stay, primaryOutcomes measure: Postoperative pain, eligibilityModule sex: ALL, minimumAge: 7 Years, maximumAge: 12 Years, stdAges: CHILD, contactsLocationsModule locations facility: Muhammad Sharif, city: Lahore, state: Punjab, zip: 53711, country: Pakistan, geoPoint lat: 31.558, lon: 74.35071, hasResults: False
protocolSection identificationModule nctId: NCT06363305, orgStudyIdInfo id: 2402-1139, briefTitle: Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2025-12-01, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-04-12, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: Skidmore College, class: OTHER, collaborators name: American Heart Association, descriptionModule briefSummary: The investigators long-term goal is to better understand novel interventions to promote cardiovascular health in humans. The goal of the proposed research is to investigate whether there is sex-specificity in the effects of dietary capsaicin on mechanisms regulating nitric oxide (NO) bioavailability, its effect on key markers of cardiovascular (CV) health, including BP, macro- and microvascular function, and arterial stiffness. This knowledge will provide critical insight into the effects of dietary capsaicin on CV health and will guide future trials., conditionsModule conditions: Pre Hypertension, conditions: Hypertension, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Parallel: Participants are randomly assigned to one of two groups in parallel for the duration of the study, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: TRIPLE, maskingDescription: The capsules will be placed into solid white color bottles, and labeled discreetly by a third party not directly involved with the research., whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Dietary capsules, outcomesModule primaryOutcomes measure: Blood Pressure and Vascular Stiffness, primaryOutcomes measure: Heart Rate (HR) and HR variability (HRV), primaryOutcomes measure: Flow Mediated Dilation, primaryOutcomes measure: Passive Leg Movement Hyperemia, primaryOutcomes measure: Near Infrared Spectroscopy (NIRS) Vascular Occlusion Test, secondaryOutcomes measure: Urinary Capsaicinoids, secondaryOutcomes measure: Blood Lipids, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Skidmore College, city: Saratoga Springs, state: New York, zip: 12866, country: United States, contacts name: Stephen Ives, Ph.D., role: CONTACT, phone: 518-580-8366, email: sives@skidmore.edu, geoPoint lat: 43.08313, lon: -73.78457, hasResults: False
protocolSection identificationModule nctId: NCT06363292, orgStudyIdInfo id: SOPH231-1221/I, briefTitle: Study to Evaluate the Safety and Tolerability of PRO-231 Ophthalmic Solution Versus VIGAMOXI® on the Ocular Surface of Healthy Subjects., statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-30, primaryCompletionDateStruct date: 2024-05-30, completionDateStruct date: 2024-05-30, studyFirstPostDateStruct date: 2024-04-12, lastUpdatePostDateStruct date: 2024-04-15, sponsorCollaboratorsModule leadSponsor name: Laboratorios Sophia S.A de C.V., class: INDUSTRY, descriptionModule briefSummary: This is a phase I clinical study evaluating the safety and tolerability of PRO-231 ophthalmic solution through the incidence of unexpected adverse events, incidence of conjunctival hyperemia and chemosis, changes in Best Corrected Visual Acuity (BCVA), changes in ocular surface integrity, compared to VIGAMOXI®., conditionsModule conditions: Ophthalmological Agent Toxicity, conditions: Bacterial Conjunctivitis, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Phase I, controlled, comparative, parallel-group, single-blind, single-center, controlled clinical trial., primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, maskingDescription: Single-blind, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 36, type: ESTIMATED, armsInterventionsModule interventions name: PRO-231, interventions name: VIGAMOXI®, outcomesModule primaryOutcomes measure: Incidence of unexpected adverse events related to the interventions, primaryOutcomes measure: Incidence of conjunctival hyperemia and chemosis, primaryOutcomes measure: Changes in Best Corrected Visual Acuity (BCVA), primaryOutcomes measure: Changes in the integrity of the ocular surface (fluorescein staining), primaryOutcomes measure: Changes in the Ocular Comfort Index (OCI) score between interventions., secondaryOutcomes measure: Incidence of unexpected adverse events (excluding conjunctival hyperemia and chemosis), secondaryOutcomes measure: To assess the tolerability of PRO-231 ophthalmic solution, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule locations facility: IIMET Investigación e Innovación en Medicina Traslacional, status: RECRUITING, city: Guadalajara, state: Jalisco, zip: 44610, country: Mexico, contacts name: Alejandro González, MD, role: CONTACT, geoPoint lat: 20.66682, lon: -103.39182, hasResults: False
protocolSection identificationModule nctId: NCT06363279, orgStudyIdInfo id: 2024/24JAN/044, briefTitle: Validation of the French ATI Scale and Predisposition to Use Technological Tools in Rehabilitation., statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-04, primaryCompletionDateStruct date: 2024-09, completionDateStruct date: 2024-10, studyFirstPostDateStruct date: 2024-04-12, lastUpdatePostDateStruct date: 2024-04-12, sponsorCollaboratorsModule leadSponsor name: Cliniques universitaires Saint-Luc- Université Catholique de Louvain, class: OTHER, descriptionModule briefSummary: Aim of the study: The first aim of this study is to validate the translation of the Affinity for Technology Interaction (ATI) questionnaire. This questionnaire was developed in English by Franke, Attig and Wessel in 2019. It consists of 9 items and was developed to assess a person's tendency to actively engage in technological interaction, or the ease with which a person uses technological tools. Currently, the questionnaire has been translated into French by our research team according to good practice recommendations (Guillemin, Bombardier and Beaton, 1993; Tsang et al., 2017), but this French version has not yet been validated. To validate the translation of a questionnaire, it is necessary to have it completed by a large number of subjects from the population of interest. In neurorehabilitation, measuring this affinity will make it possible to better identify patients who are more likely to adhere to tele-rehabilitation and thus direct them towards this type of treatment as a complement to conventional rehabilitation.The second objective is to determine the extent to which the general population is prepared to use technological tools as part of their rehabilitation. The aim is to gain a better understanding of the profile of people who could potentially benefit from tele-rehabilitation. Accessibility to the technologies, their expectations and barriers will also be explored as part of this study., conditionsModule conditions: Stroke, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 1000, type: ESTIMATED, armsInterventionsModule interventions name: Conducting questionnaires, outcomesModule primaryOutcomes measure: ATI - affinity technology interaction scale, secondaryOutcomes measure: Scale for assessing a person's readiness to use technological tools as part of their rehabilitation, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Clinique Universitaires Saint-Luc, status: RECRUITING, city: Brussel, state: Woluwé-Saint-Lambert, zip: 1200, country: Belgium, contacts name: Thierry Lejeune, MD, PhD, role: CONTACT, phone: +3227641648, email: thierry.lejeune@saintluc.uclouvain.be, contacts name: Mathilde Van Durme, role: CONTACT, phone: +3227641675, email: mathilde.vandurme@saintluc.uclouvain.be, geoPoint lat: 50.85045, lon: 4.34878, hasResults: False
protocolSection identificationModule nctId: NCT06363253, orgStudyIdInfo id: CIRB Ref: 2023/2073, briefTitle: Pilot Study of the Human Metagenome in Metabolic Diseases, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-08-14, primaryCompletionDateStruct date: 2026-12-31, completionDateStruct date: 2027-12-31, studyFirstPostDateStruct date: 2024-04-12, lastUpdatePostDateStruct date: 2024-04-12, sponsorCollaboratorsModule leadSponsor name: Sengkang General Hospital, class: OTHER, collaborators name: Singapore General Hospital, collaborators name: Lee Kong Chian School of Medicine, Nanyang Technological University, collaborators name: Duke-NUS Graduate Medical School, descriptionModule briefSummary: This is a cohort study to understand the role of the human metagenome, and associated metabolites, in health and in various diseased states, in particular obesity as well as sarcopenia.Recruited participants will have their fecal, salivary, urine, serum, and in certain instances, mucosal samples taken, for metagenomic sequencing and metabolite testing.We hope to uncover various differences and signatures in the metagenome and metabolome in various diseased states, with potential future therapeutic applications in personalised medicine., conditionsModule conditions: Obesity, conditions: Sarcopenia, conditions: Sarcopenic Obesity, conditions: Chronic Inflammation, conditions: Metabolic Syndrome, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 600, type: ESTIMATED, armsInterventionsModule interventions name: No specific intervention, outcomesModule primaryOutcomes measure: Metagenomic alterations, primaryOutcomes measure: Metabolomic alterations, eligibilityModule sex: ALL, minimumAge: 21 Years, maximumAge: 99 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Sengkang General Hospital, status: RECRUITING, city: Singapore, zip: 544886, country: Singapore, contacts name: Koy Min Chue, role: CONTACT, phone: 69305000, email: chue.koy.min@singhealth.com.sg, geoPoint lat: 1.28967, lon: 103.85007, hasResults: False
protocolSection identificationModule nctId: NCT06363240, orgStudyIdInfo id: CBBLCIP001, briefTitle: Evaluation of Broadband Light Treatment for Solar Lentigines, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-12, primaryCompletionDateStruct date: 2024-12-20, completionDateStruct date: 2025-01-30, studyFirstPostDateStruct date: 2024-04-12, lastUpdatePostDateStruct date: 2024-04-12, sponsorCollaboratorsModule leadSponsor name: Sciton, class: INDUSTRY, descriptionModule briefSummary: Broadband light treatment for Solar Lentigines, conditionsModule conditions: Solar Lentigo, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: Broadband Light, outcomesModule primaryOutcomes measure: Changes in skin post treatment, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Sanctuary Plastic Surgery, status: RECRUITING, city: Boca Raton, state: Florida, zip: 33431, country: United States, contacts name: Jonathan Cook, MD, role: CONTACT, geoPoint lat: 26.3669, lon: -80.13033, hasResults: False
protocolSection identificationModule nctId: NCT06363227, orgStudyIdInfo id: ANEST-0003, briefTitle: Postoperative Pain After Implementation of Standardized Pain Therapy Management in Orthopaedic Patients, acronym: PAIN, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2025-02, completionDateStruct date: 2025-04, studyFirstPostDateStruct date: 2024-04-12, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Schulthess Klinik, class: OTHER, descriptionModule briefSummary: The aim of this study is to examine the impact of implementing a standardized pain therapy protocol and their components on postoperative pain trajectories and postoperative outcomes such as increased opioid consumption and to compare it for different orthopaedic operations, i.e. major shoulder, hip, knee und spine surgery., conditionsModule conditions: Postoperative Pain, Acute, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 12000, type: ESTIMATED, armsInterventionsModule interventions name: Standardized pain management, outcomesModule primaryOutcomes measure: Perioperative pain trajectories, primaryOutcomes measure: Increased risk for postoperative pain, secondaryOutcomes measure: Total amount of opioids administered, secondaryOutcomes measure: Correlation of pain trajectories and patient reported outcome measures (e.g. postoperative nausea and vomiting), eligibilityModule sex: ALL, minimumAge: 16 Years, maximumAge: 99 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06363214, orgStudyIdInfo id: ANEST-0002, briefTitle: Impact of Patient Blood Management (PBM) at the Schulthess Clinic, acronym: PBM, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2025-02, completionDateStruct date: 2025-04, studyFirstPostDateStruct date: 2024-04-12, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: Schulthess Klinik, class: OTHER, descriptionModule briefSummary: Aim of this study is to analyze the transfusion requirements of allogenic blood products at the Schulthess Clinic for patients that had major orthopedic or major spine surgery between 2019 and 2024 order to identify patients at risk for transfusion. Moreover, impact of transfusion requirements and other measures of PBM on patient outcomes will be assessed. These data are required to further improve PBM at the Schulthess Clinic., conditionsModule conditions: Patient Blood Management, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 16000, type: ESTIMATED, armsInterventionsModule interventions name: Patient blood management, outcomesModule primaryOutcomes measure: Perioperative transfusion rates, primaryOutcomes measure: Risk factors for perioperative transfusion Risk factors for perioperative transfusion Risk factorsfor perioperative transfusion, secondaryOutcomes measure: Perioperative rates of coagulation products administered, secondaryOutcomes measure: Clinical outcomes, eligibilityModule sex: ALL, minimumAge: 16 Years, maximumAge: 99 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06363201, orgStudyIdInfo id: CAT2024/PED01, briefTitle: Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid Tumours, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-28, primaryCompletionDateStruct date: 2024-12-15, completionDateStruct date: 2025-12-15, studyFirstPostDateStruct date: 2024-04-12, lastUpdatePostDateStruct date: 2024-04-12, sponsorCollaboratorsModule leadSponsor name: Catalysis SL, class: INDUSTRY, descriptionModule briefSummary: Exploratory study to evaluate the effect and safety of the use of Ocoxin® oral solution on the quality of life of paediatric patients with advanced stage solid tumours., conditionsModule conditions: Advanced Cancer, conditions: Advanced Solid Tumor, conditions: Lymphoma, Hodgkin, conditions: Central Nervous System Tumor, conditions: Sarcoma, conditions: Germ Cell Tumor, conditions: Pediatric Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Ocoxin Oral solution, outcomesModule primaryOutcomes measure: Quality of Life, secondaryOutcomes measure: Degree of toxicity related to oncospecific treatment, secondaryOutcomes measure: Nutritional Status, secondaryOutcomes measure: Presence of Adverse Events (AE), secondaryOutcomes measure: Metabolic Status, secondaryOutcomes measure: Physical Status, secondaryOutcomes measure: Response to oncospecific treatment, eligibilityModule sex: ALL, minimumAge: 7 Years, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Hospital Escuela, Tegucigalpa (Honduras), city: Tegucigalpa, state: Francisco Morazan, zip: 504, country: Honduras, contacts name: Ingrid C. Arambú Elvir, Dr., role: CONTACT, phone: 50498878486, email: ingridcarolinaa@yahoo.com, contacts name: Ingrid C. Arambú Elvir, Dr., role: PRINCIPAL_INVESTIGATOR, contacts name: Alejandra Elonor Zapata, Dr., role: SUB_INVESTIGATOR, contacts name: Clarissa L. Aguilar Molina, Dr., role: SUB_INVESTIGATOR, contacts name: Darío Vinicio Cáceres, Dr., role: SUB_INVESTIGATOR, contacts name: Gerardo Ismael Castro, Dr., role: SUB_INVESTIGATOR, geoPoint lat: 14.0818, lon: -87.20681, hasResults: False