hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06289283, orgStudyIdInfo id: Theodor Bilharz Research Ins., briefTitle: Microbiota in Urine and Urothelium Can be a Factor for Induction of Urinary Bladder Cancer. The Study Will Examine Urine and Bladder Cancer Tissues From Male Patients and Urine of Controls Using Whole Genomic Sequencing Techniques and 16S rRNA. The Aim is to Elucidate Role of Microbiota in Bladder, acronym: Cancer bladder, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-10-12, primaryCompletionDateStruct date: 2026-04, completionDateStruct date: 2026-12, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Theodor Bilharz Research Institute, class: OTHER, descriptionModule briefSummary: Microbes inhabiting the urinary tract that are playing an important role in maintenance of health and the development of diseases and bladder cancer. There is correlation between initiation of bladder cancer and microbes. Urine and bladder tissues from healthy individuals and patients with bladder cancer were analyzed using 16S rRNA sequencing, results show abundant phylum. Next-generation sequencing technologies will be applied with whole genomic and 16S ribosomal RNA gene sequencing for microbiota profiling in urine and bladder tissue of male healthy individuals and patients with bladder cancer. Results will lead to prevention, diagnosis and new treatment strategies for bladder cancer., conditionsModule conditions: Urinary Bladder Neoplasms, conditions: Microtia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 38, type: ACTUAL, armsInterventionsModule interventions name: Urine samples and tissue samples: Samples will be collected in clean leak-proof containers without disinfectant or detergent residue and with tight-fitting leak-proof lids and preserved in a refrigera, outcomesModule primaryOutcomes measure: To characterize the microbiota in health and bladder cancer, and may lead to new prevention, diagnosis and treatment strategies for bladder cancer, eligibilityModule sex: MALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Theodor Bilharz Research Institute, city: Cairo, zip: 12411, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06289270, orgStudyIdInfo id: Microbiota and bladder cancer, briefTitle: Microbiota in Urine and Urothelium Can be a Factor for Induction of Urinary Bladder Cancer. The Study Will Examine Urine and Bladder Tissues From Egyptian Male Patients and Controls Using Whole Genomic Sequencing Techniques and 16S rRNA. The Aim is to Elucidate Role of Microbiota in Bladder Cancer., acronym: Cancer bladder, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-09-20, primaryCompletionDateStruct date: 2026-12, completionDateStruct date: 2027-07, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Theodor Bilharz Research Institute, class: OTHER, descriptionModule briefSummary: Microbes inhabiting the urinary tract that are playing an important role in maintenance of health and the development of diseases and bladder cancer. There is correlation between initiation of bladder cancer and microbes. Urine and bladder tissues from healthy individuals and patients with bladder cancer were analyzed using 16S rRNA sequencing, results show abundant phylum. Next-generation sequencing technologies will be applied with whole genomic and 16S ribosomal RNA gene sequencing for microbiota profiling in urine and bladder tissue of male healthy individuals and patients with bladder cancer. Results will lead to prevention, diagnosis, and new treatment strategies for bladder cancer., conditionsModule conditions: Microbiota in Patients With Urinary Bladder Carcinoma in Urine and Cancer Tissues, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 38, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: To characterize the microbiota in male patients with bladder cancer., eligibilityModule sex: MALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Theodor Bilharz Research Institute, status: NOT_YET_RECRUITING, city: Cairo, state: Giza, zip: 12411, country: Egypt, contacts name: Mohamed M Wishahi, MD, role: CONTACT, phone: +201222247437, email: wishahi@gmx.net, geoPoint lat: 30.06263, lon: 31.24967, locations facility: Theodor Bilharz Research Institute, status: RECRUITING, city: Cairo, zip: 12411, country: Egypt, contacts name: Mohamed M Wishahi, MD, role: CONTACT, phone: +201222247437, email: wishahi@gmx.net, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06289244, orgStudyIdInfo id: 6597, briefTitle: Correlation Between Muscle Strength and Thickness in Critically Ill Patients, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-06-06, primaryCompletionDateStruct date: 2025-03-30, completionDateStruct date: 2025-06-30, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, class: OTHER, descriptionModule briefSummary: Mechanical ventilation (MV) is associated with adverse outcomes in ventilated patients, and impact of MV-induced diaphragm changes are still unclear.The objective of this prospective observational study is to assess muscle thickness and strength, specifically in limb muscles such as the quadriceps, among critically ill patients who undergo extended mechanical ventilation during their Intensive Care Unit (ICU) stay.The primary inquiries this study seeks to address are:* Is there an association between muscle thickness and strength in the limbs of critically ill patients undergoing prolonged MV?* How much thickness and strength variation can be expected in respiratory and limb muscles in critically ill patients undergoing prolonged MV?, conditionsModule conditions: Critical Illness, conditions: Muscle Weakness, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Ultrasound, interventions name: Muscle strength measurement, outcomesModule primaryOutcomes measure: Correlation between quadriceps strength and thickness, secondaryOutcomes measure: Quadriceps strength, secondaryOutcomes measure: Quadriceps thickness, secondaryOutcomes measure: Diaphragm thickness, secondaryOutcomes measure: Diaphragm strength, secondaryOutcomes measure: Time to reach the sitting position, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, status: RECRUITING, city: Milan, zip: 20122, country: Italy, contacts name: Veronica Rossi, MSc, role: CONTACT, email: veronica.rossi@policlinico.mi.it, geoPoint lat: 45.46427, lon: 9.18951, hasResults: False
protocolSection identificationModule nctId: NCT06289231, orgStudyIdInfo id: AWFiS/2023_5_PE, briefTitle: The Use of Artificial Intelligence (AI) for Gait Analysis, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2024-07, completionDateStruct date: 2024-08, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Gdansk University of Physical Education and Sport, class: OTHER, descriptionModule briefSummary: The main purpose of this study will be to assess the consistency and reliability of measurements made using the Vicon three-plane gait analysis device (Vicon Motion Capture System Ltd, Oxford, UK) and a mobile application based on image recognition technology with the help of artificial intelligence., conditionsModule conditions: Gait, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 50, type: ESTIMATED, outcomesModule primaryOutcomes measure: Gait analysis by the Vicon system, primaryOutcomes measure: Gait analysis by the mobile image recognition application, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 25 Years, stdAges: ADULT, contactsLocationsModule locations facility: Gdansk University of Physical Education and Sport, city: Gdańsk, state: Pomorskie, zip: 80-336, country: Poland, geoPoint lat: 54.35205, lon: 18.64637, hasResults: False
protocolSection identificationModule nctId: NCT06289218, orgStudyIdInfo id: Treating knee osteoarthritis, briefTitle: Kinesio Taping Versus Interferential Current Therapy in Treating Knee Osteoarthritis, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-25, primaryCompletionDateStruct date: 2025-06, completionDateStruct date: 2025-09, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-05, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: The purpose of this study will be to compare the combined effect of using Kinesio taping versus interferential current with an exercise program on knee pain, function, knee range of motion, knee muscle strength, and functional mobility in chronic knee osteoarthritis., conditionsModule conditions: Knee Osteoarthritis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 48, type: ESTIMATED, armsInterventionsModule interventions name: interferential current, interventions name: kinesio taping, interventions name: exercise, outcomesModule primaryOutcomes measure: knee flexion range of motion, primaryOutcomes measure: knee extension range of motion, primaryOutcomes measure: quadriceps muscle strength, primaryOutcomes measure: The Western Ontario and McMaster Universities Osteoarthritis Index, primaryOutcomes measure: Timed up and go test, eligibilityModule sex: ALL, minimumAge: 40 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06289179, orgStudyIdInfo id: Thyroid and cortisol in sepsis, briefTitle: Thyroid and Cortisol Hormone Response to Sepsis, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2026-02-20, completionDateStruct date: 2026-10-25, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: Thyroid and cortisol hormone response to sepsis, conditionsModule conditions: Sepsis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 114, type: ESTIMATED, outcomesModule primaryOutcomes measure: Pattern of cortisol level and thyroid function response to sepsis in ICU, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 100 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06289153, orgStudyIdInfo id: 23-01182, briefTitle: Internal Bracing Following ACL Reconstruction, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2025-02-26, completionDateStruct date: 2025-08-26, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: NYU Langone Health, class: OTHER, descriptionModule briefSummary: The purpose of this study is to assess Anterior Cruciate Ligament (ACL) healing through analyzing clinical, radiographic, functional and patient-reported outcomes following ACL reconstruction with quadriceps graft with and without internal bracing., conditionsModule conditions: ACL Injury, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Arthrex Internal Brace, interventions name: ACL Reconstruction, outcomesModule primaryOutcomes measure: Change from Baseline in 2000 International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Form at Month 6 Post-Operation, primaryOutcomes measure: Change from Baseline in 2000 IKDC Subjective Knee Evaluation Form Score at Month 12 Post-Operation, primaryOutcomes measure: Change from Baseline in Lysholm Knee Scoring System Score at Month 6 Post-Operation, primaryOutcomes measure: Change from Baseline in Lysholm Knee Scoring System Score at Month 12 Post-Operation, primaryOutcomes measure: Change from Baseline in Visual Analogue Scale (VAS) - Pain Score at Month 6 Post-Operation, primaryOutcomes measure: Change from Baseline in Visual Analogue Scale (VAS) - Pain Score at Month 12 Post-Operation, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: NYU Langone Health, status: RECRUITING, city: New York, state: New York, zip: 10016, country: United States, geoPoint lat: 40.71427, lon: -74.00597, hasResults: False
protocolSection identificationModule nctId: NCT06289140, orgStudyIdInfo id: BIOPTERO2, briefTitle: Oral Bioavailability of a New Formulation of Pterostilbene Cocrystal in Comparison With Its Free Form (BIOPTERO2), acronym: BIOPTERO2, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2024-04, completionDateStruct date: 2024-04, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Fundació Eurecat, class: OTHER, collaborators name: Circe, S.L., descriptionModule briefSummary: The goal of this interventional study is to to evaluate the oral bioavailability of the crystallized form of pterostilbene (ccPT) compared to its commercial free base form (pterostilbene (PT) in healthy volunteers. The main question it aims to answer are:• Do the crystallized forms of pterostilbene (ccPT) using two different encapsulation methods exhibit greater bioavailability than its commercial free base form (PT)?Participants will attend to four visits: a preselection visit (V0), a visit for the first postprandial study (V1), a visit for the second postprandial study (V2) after one-week washing period and a visit for the third postprandial study (V3) after another one week washing period.Researchers will analyze the three postprandial assays to determine which type of ccPT encapsulation provides the highest bioavailability compared to the commercial free base form (PT)., conditionsModule conditions: Biological Availability, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: OTHER, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 6, type: ESTIMATED, armsInterventionsModule interventions name: Pterostilbene cocrystal (ccPT) - Gelatin capsule, interventions name: Pterostilbene free form (PT), interventions name: Pterostilbene cocrystal (ccPT) - Gastro-resistant capsule, outcomesModule primaryOutcomes measure: Bioavailability of Pterostilbene calculated by area under the curve (AUC 0-24) of plasma pterostilbene levels, both free and total., secondaryOutcomes measure: Area under the curve (AUC 0-inf) of plasma pterostilbene levels, both free and total., secondaryOutcomes measure: Relative bioavailability of plasma pterostilbene levels (Frel)., secondaryOutcomes measure: Maximum plasma concentration (Cmax), secondaryOutcomes measure: Time for maximum plasma concentration (Tmax), secondaryOutcomes measure: Half-life (T1/2)., eligibilityModule sex: MALE, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Fundació Eurecat, city: Reus, zip: 43204, country: Spain, contacts name: Antoni Caimari, PhD, role: CONTACT, phone: 0034 977 300 431, email: antoni.caimari@eurecat.org, contacts name: Anna Crescenti, PhD, role: CONTACT, phone: 0034 977 300 431, email: anna.crescenti@eurecat.org, geoPoint lat: 41.15612, lon: 1.10687, hasResults: False
protocolSection identificationModule nctId: NCT06289127, orgStudyIdInfo id: GO 22/595, briefTitle: Test Properties of Lower Quarter Y-Balance Test: Effect of Verbal Instructions and Focus Techniques, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-07-20, primaryCompletionDateStruct date: 2023-02-02, completionDateStruct date: 2023-11-10, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Hacettepe University, class: OTHER, descriptionModule briefSummary: The Lower Quadrant Y-Balance Test (LQYBT) is a landmark test used in assessing lower extremity performance, determining risk factors for injury, and making return-to-sport decisions. Studies have shown that the individual's focus of attention affects balance. The literature, has shown that the use of external focus is more effective than the use of internal focus in the execution of a movement.Consistent with these findings, the use of an external focus instruction during the LQYBT may lead to achieve more realistic and a higher performance outcome than the test result with standard instructions. The primary aim of this study was to investigate the effects of using different instructions and focusing techniques on test performance on the LQYBT. The secondary aim was to investigate the reliability of the different instructions and focus tests we used for the LQYBT.Hypothesis of the study that test performance can be further enhanced by differentiating the instructions and focus techniques. A more effective assessment of individual performance may help us to make a more realistic decision to return to sport., conditionsModule conditions: Healthy, conditions: Attention Disturbances, conditions: Physical Stress, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 2, type: ACTUAL, armsInterventionsModule interventions name: Lower Quarter Y Balance Test, outcomesModule primaryOutcomes measure: Investigate the effects of using different instructions and focusing techniques on test performance on the LQYBT., secondaryOutcomes measure: Investigate the reliability of the different instructions and focus tests we used for the LQYBT., eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 35 Years, stdAges: ADULT, contactsLocationsModule locations facility: Hacettepe University, city: Ankara, state: Sıhhıye, zip: 06430, country: Turkey, geoPoint lat: 39.91987, lon: 32.85427, hasResults: False
protocolSection identificationModule nctId: NCT06289101, orgStudyIdInfo id: IRB00422008, secondaryIdInfos id: R21HD112617, type: NIH, link: https://reporter.nih.gov/quickSearch/R21HD112617, briefTitle: text4FATHER R21: Social Media - Efficacy Trial, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2025-05, completionDateStruct date: 2025-06, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Johns Hopkins University, class: OTHER, collaborators name: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), descriptionModule briefSummary: This project will be the first to examine the efficacy of a text messaging intervention designed to recruit first-time fathers-to-be using social media across the U.S. to become involved during pregnancy through two months of postnatal age to support infant, mother, and father well-being., conditionsModule conditions: Fathers, conditions: Mobile Health, conditions: Nuclear Family, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: 2 groups will be enrolled and randomized to receipt or not receipt of the intervention., primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 180, type: ESTIMATED, armsInterventionsModule interventions name: text4FATHER, outcomesModule primaryOutcomes measure: Change in Self-efficacy as assessed by the Parenting Sense of Competence Scale (PSOC), primaryOutcomes measure: Karitane Parenting Confidence Scale (KPCS), primaryOutcomes measure: Fathering Self-Efficacy Scale (FSES), primaryOutcomes measure: Father Engagement Scale (FES), primaryOutcomes measure: The Co-Parenting Relationship Scale, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Johns Hopkins Hospital, city: Baltimore, state: Maryland, zip: 21287, country: United States, geoPoint lat: 39.29038, lon: -76.61219, hasResults: False
protocolSection identificationModule nctId: NCT06289088, orgStudyIdInfo id: E-10840098-772.02-4659, briefTitle: The Effect of an Individually Adapted Lumbosacral Orthosis on Plantar Pressure and Balance, acronym: lumbosacral, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-03-04, primaryCompletionDateStruct date: 2024-05-04, completionDateStruct date: 2024-05-04, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: Istanbul Medipol University Hospital, class: OTHER, descriptionModule briefSummary: The aim of this study is to examine the effect of steel underwire lumbosacral orthosis adapted to the individual by the prosthetist orthotist on pain, comfort, plantar pressure, static and dynamic balance in individuals with low back pain., conditionsModule conditions: Orthosis, conditions: Low Back Pain, Postural, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: Single group, crossover study, primaryPurpose: OTHER, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: First Intervention, interventions name: Second Intervention, interventions name: Third Intervention, outcomesModule primaryOutcomes measure: Visual Analog scale, primaryOutcomes measure: Orthosis comfort score, primaryOutcomes measure: Functional Reach Test (FRT), primaryOutcomes measure: Pedobarographic evaluation, primaryOutcomes measure: Y balance test, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Istanbul Medipol University, city: Istanbul, country: Turkey, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False