protocolSection identificationModule nctId: NCT06304753, orgStudyIdInfo id: BOT119435, briefTitle: ContriBution of Digital RemOte MoniToring to IMPROVing The Effectiveness of Treatment in Patients With Chronic Heart Failure With Low Ejection Fraction, acronym: BOT-IMPROVE-HF, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-10-27, primaryCompletionDateStruct date: 2025-07-01, completionDateStruct date: 2025-12-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: I.M. Sechenov First Moscow State Medical University, class: OTHER, descriptionModule briefSummary: BOT-IMPROVE-HF is a two-center, parallel group study designed to evaluate the efficacy of up-titration of heart failure treatment using digital remote monitoring after hospitalization due to heart failure decompensation. Patient will be randomized before discharge using a simple computer generated sequence to either remote monitoring or usual care group. Patients' condition in the "remote monitoring" arm will be assessed by mini-program based on a personal messenger and laboratory rests results will be asked by phone call. If these measures show safety and tolerability of the doses of the drugs, they will be increased to target or maximally tolerated doses. The follow-up period will be 6 months - 24 weeks. Patients of the usual care group will be followed by their general practitioner and/or cardiologist. All patients will be contacted after 6 months to assess outcomes., conditionsModule conditions: Chronic Heart Failure With Low Ejection Fraction, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Telebot, outcomesModule primaryOutcomes measure: All-cause mortality, primaryOutcomes measure: Heart failure decompensation, secondaryOutcomes measure: Change in NT-proBNP, secondaryOutcomes measure: Change in Quality of life, secondaryOutcomes measure: Changes in medical adherence, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 85 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hospital Therapy No. 1 Department, University Clinical Hospital No. 1, Sechenov University, status: RECRUITING, city: Moscow, zip: 119435, country: Russian Federation, contacts name: Maria Kozhevnikova, role: CONTACT, phone: +7 (499) 248-46-43, email: kozhevnikova_m_v@staff.sechenov.ru, contacts name: Aleksei Emelianov, role: CONTACT, phone: +7 (999) 830-57-85, email: emelyanov_a_v@staff.sechenov.ru, geoPoint lat: 55.75222, lon: 37.61556, locations facility: State Budgetary Institution of Healthcare of Moscow "A.K. Yeramishantsev City Clinical Hospital of the Department of Healthcare of Moscow"., status: RECRUITING, city: Moscow, zip: 129327, country: Russian Federation, contacts name: Maria Kozhevnikova, role: CONTACT, phone: +74992484643, email: kozhevnikova_m_v@staff.sechenov.ru, contacts name: Aleksei Emelianov, role: CONTACT, phone: +79998305785, email: emelyanov_a_v@staff.sechenov.ru, geoPoint lat: 55.75222, lon: 37.61556, hasResults: False