hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06348953, orgStudyIdInfo id: Bioactive restorative system, briefTitle: Bioactive Versus Non-Bioactive Restorative System in Deep Carious Molars, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-11, completionDateStruct date: 2025-11, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: This research study delves into the effectiveness of bioactive and non-bioactive restorative systems in deep carious permanent molars treated with selective caries removal. Selective caries removal techniques aim to preserve as much healthy tooth structure as possible while effectively eliminating carious tissue. The study investigates how the choice of restorative material influences the outcomes of selective caries removal procedures in deep carious lesions. By assessing factors such as restoration integrity, pulpal response, and long-term success rates, the research seeks to provide evidence-based insights into the comparative performance of bioactive and non-bioactive restorative systems in this clinical context., conditionsModule conditions: Dental Caries, conditions: Dental Diseases, conditions: Deep Caries, conditions: Tooth Diseases, conditions: Tooth Decay, conditions: Teeth; Lesion, conditions: Caries; Dentin, conditions: Dental Restoration Failure of Marginal Integrity, conditions: Tooth Demineralization, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: selective caries removal and conventional non-bioactive restorative system, interventions name: selective caries removal and bioactive restorative system, outcomesModule primaryOutcomes measure: Biological properties - Post Operative Hypersensitivity and Vitality-Success rate%-Scoring system:Ordinal1-5, secondaryOutcomes measure: Functional properties - fracture&retention-marginal adaptation-Radiographic Examination"when applicable"-Scoring system Ordinal 1-5, secondaryOutcomes measure: Biological properties (Recurrence of caries (CAR), erosion, abfraction- Scoring system Ordinal 1-5), secondaryOutcomes measure: Success or Failure, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06348927, orgStudyIdInfo id: DZ2023EI004, briefTitle: Sunvozertinib Plus Anlotinib as 1L Treatment in EGFR-Sensitive Mutations Combined With Co-Mutations Advanced NSCLC, acronym: WUKONG-32, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-30, primaryCompletionDateStruct date: 2025-10-31, completionDateStruct date: 2027-04-30, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Hunan Province Tumor Hospital, class: OTHER, descriptionModule briefSummary: This is a phase II, open-label, single-arm, single-center clinical study to evaluate the preliminary efficacy of sunvozertinib in combination with anlotinib in patients with EGFR-sensitive mutations and co-mutations in locally advanced or metastatic treatment-naive non-small cell lung cancer.Condition or disease Intervention/treatment Phase Non-Small Cell Lung Cancer Drug: sunvozertinib Drug: anlotinib Phase 2, conditionsModule conditions: Non-Small Cell Lung Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 52, type: ESTIMATED, armsInterventionsModule interventions name: sunvozertinib in combination with Anlotinib, outcomesModule primaryOutcomes measure: Progression-free survival (PFS), secondaryOutcomes measure: Objective Response Rate (ORR), secondaryOutcomes measure: Overall survival (OS), secondaryOutcomes measure: Duration of Response (DoR), secondaryOutcomes measure: Adverse events (AEs) according to CTCAE 5.0, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hunan Cancer Hospital, city: Changsha, state: Hunan, zip: 410013, country: China, geoPoint lat: 28.19874, lon: 112.97087, hasResults: False
protocolSection identificationModule nctId: NCT06348914, orgStudyIdInfo id: 6991, briefTitle: Knowledge of Vital Pulp Therapy in Permanent Teeth Among a Group of Dental Students in Egypt, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09-10, primaryCompletionDateStruct date: 2024-11-10, completionDateStruct date: 2024-12-30, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: Conducting this questionnaire will help in collecting information about the extent of knowledge of vital pulp therapy in permanent teeth among dental students in Egypt. This will aid in identifying the knowledge gap, interest, and challenges regarding utilization of vital pulp therapy in permanent teeth., conditionsModule conditions: Vital Pulp Therapy, designModule studyType: OBSERVATIONAL, designInfo observationalModel: ECOLOGIC_OR_COMMUNITY, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 323, type: ESTIMATED, armsInterventionsModule interventions name: Knowledge assessment, interventions name: Educational Material, outcomesModule primaryOutcomes measure: Knowledge of vital pulp therapy, secondaryOutcomes measure: Knowledge after awareness about vital pulp therapy, eligibilityModule sex: ALL, minimumAge: 15 Years, maximumAge: 25 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06348901, orgStudyIdInfo id: 2021-09-001, briefTitle: Clinical Utility of Oxford Cognitive Screen Test to Screen Cognitive Impairment in Post Stroke Patients, statusModule overallStatus: RECRUITING, startDateStruct date: 2021-09-01, primaryCompletionDateStruct date: 2025-02-28, completionDateStruct date: 2025-02-28, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Bundang CHA Hospital, class: OTHER, descriptionModule briefSummary: The goal of this type of study: clinical trial is to assess K-OCS clinical utility in participant population. The main aims:validate the reliability and validity of the Korean version of the Oxford Cognitive Screen (K-OCS) analyze its sensitivity, specificity, and diagnostic accuracy, and compare its examination participation rates with existing assessment tools to determine the effectiveness of K-OCS in detecting post-stroke cognitive impairment., conditionsModule conditions: Stroke, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Measurement of K-OCS, secondaryOutcomes measure: Measurement of Korean version of mini-mental state examination (K-MMSE), secondaryOutcomes measure: Measurement Korean Version of the Oxford cognitive screen (K-OCS), secondaryOutcomes measure: Measurement of national institute of health care stroke scale (NIHSS), secondaryOutcomes measure: Measurement of fuctional independence meausure (FIM), eligibilityModule sex: ALL, minimumAge: 20 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Department of Rehabilitation Medicine, CHA Bundang Medical Center, status: RECRUITING, city: Seongnam-si, state: Gyeonggi-do, zip: 13496, country: Korea, Republic of, contacts name: Eunyoung Cho, role: CONTACT, phone: +82-10-2753-0285, email: a220242@chamc.co.kr, geoPoint lat: 37.43861, lon: 127.13778, hasResults: False
protocolSection identificationModule nctId: NCT06348875, orgStudyIdInfo id: CLN-PLAN-102v1, briefTitle: Clinical Evaluation of Radiation Reduction for Optimized Safety, acronym: CERROS, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-15, primaryCompletionDateStruct date: 2024-07-15, completionDateStruct date: 2024-07-31, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Angiowave Imaging, class: INDUSTRY, descriptionModule briefSummary: The primary objective of this study is to determine whether a reduced radiation protocol (RRP) in which angiograms are acquired at ultralow radiation doses and then processed using spatiotemporal enhancement software can produce similar quality angiographic images as compared with standard techniques., conditionsModule conditions: Coronary Artery Disease, conditions: Myocardial Infarction, conditions: Coronary Disease, conditions: Coronary Stenosis, conditions: Angina Pectoris, conditions: Chest Pain, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 50, type: ESTIMATED, outcomesModule primaryOutcomes measure: Segment-level percent diameter stenosis (%DS), secondaryOutcomes measure: Stenosis severity, secondaryOutcomes measure: Diagnostic quality, secondaryOutcomes measure: Radiation dose - SOC, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Corewell Health West, city: Grand Rapids, state: Michigan, zip: 49503, country: United States, contacts name: Ryan Madder, MD, role: CONTACT, phone: 616-391-4327, email: Ryan.Madder@corewellhealth.org, contacts name: Timothy Joseph, MD, role: CONTACT, phone: 616-391-4327, email: stacie.vanoosterhout@corewellhealth.org, contacts name: Ryan Madder, MD, role: PRINCIPAL_INVESTIGATOR, contacts name: Timothy Joseph, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 42.96336, lon: -85.66809, hasResults: False
protocolSection identificationModule nctId: NCT06348862, orgStudyIdInfo id: 323/REC/2023, briefTitle: Assessment of Stress and Anxiety for Patients Undergoing MRI Using, Holy Quran, Music, and Natural Sounds, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-31, primaryCompletionDateStruct date: 2024-06-30, completionDateStruct date: 2024-06-30, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Al-Quds University, class: OTHER, descriptionModule briefSummary: The aim of the current study is to analyze the effect of listening to Quran or music or natural sounds on anxiety and stress level among patients undergoing MRI., conditionsModule conditions: Anxiety, conditions: Stress, conditions: MRI Contrast Media Adverse Reaction, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: DOUBLE, maskingDescription: Double blinded, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 400, type: ESTIMATED, armsInterventionsModule interventions name: Listening to either Quran, Music, and or Natural sound, outcomesModule primaryOutcomes measure: Level of Anxiety among patients who underwent MRI, primaryOutcomes measure: Level of Stress, secondaryOutcomes measure: Sociodemographic, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06348849, orgStudyIdInfo id: 0797-11/2023, briefTitle: The Desensitising Effect of Nanosilver Fluoride in Molar-Incisor Hypomineralisation, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2024-06, completionDateStruct date: 2024-07, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Alexandria University, class: OTHER, descriptionModule briefSummary: The aim of the current study is to assess the desensitising effect of nanosilver fluoride on first permanent molars (FPMs) in patients with MIH in comparison to low-level laser therapy., conditionsModule conditions: Molar Incisor Hypomineralization, conditions: Hypersensitivity, designModule studyType: INTERVENTIONAL, phases: PHASE2, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 120, type: ESTIMATED, outcomesModule primaryOutcomes measure: Desensitising effect in hypersensitive MIH molars, secondaryOutcomes measure: Change in the plaque index scores, secondaryOutcomes measure: Change in children's frequency of toothbrushing, eligibilityModule sex: ALL, minimumAge: 7 Years, maximumAge: 10 Years, stdAges: CHILD, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06348836, orgStudyIdInfo id: 2123624-1/2, briefTitle: The Effects of Open Chain Versus Closed Chain Strengthening on Dynamic Valgus During a Step Down Test, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-22, primaryCompletionDateStruct date: 2025-02-28, completionDateStruct date: 2025-02-28, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Alvernia University, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to compare the effects of different exercises programs in individuals with abnormal knee motion. The main question it aims to answer are:* In individuals with abnormal knee motion and without knee pain, does a weight-bearing exercise program reduce abnormal knee motion during a step-down test better than a non weight-bearing exercise program? Participants will* Perform a stepdown test while undergoing motion analysis and electromyograph (EMG) recording.* Participants will then be placed either into a weight-bearing or non weight-bearing exercise group. Exercises will be performed 3 times per week for 6 weeks.* Further motion analysis and EMG data will be collected to test for differences. Researchers will compare individual results before and after exercise, and between-group results before and after exercise to see if one exercise program helps improved abnormal knee motion more than the other., conditionsModule conditions: Dynamic Knee Valgus, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Participants will be randomly assigned to either a closed-chain (weightbearing) exercise group or an open-chain (non-weightbearing) exercise group, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 10, type: ESTIMATED, armsInterventionsModule interventions name: Exercise, outcomesModule primaryOutcomes measure: Electromyographic activity of gluteus medius muscle during step-down test, primaryOutcomes measure: Electromyographic activity of quadriceps muscle during step-down test, primaryOutcomes measure: Electromyographic activity of hamstring muscles during step-down test, secondaryOutcomes measure: Amount of dynamic knee valgus during step-down test measured with motion analysis, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Alvernia University, status: RECRUITING, city: Reading, state: Pennsylvania, zip: 19607, country: United States, contacts name: James M O'Donohue, DPT, role: CONTACT, phone: 610-334-1162, email: jim@odfamily.com, geoPoint lat: 40.33565, lon: -75.92687, hasResults: False
protocolSection identificationModule nctId: NCT06348823, orgStudyIdInfo id: BritishUE, briefTitle: Relationship Between Soft Tissue Volume and Gingival Phenotype: A Novel Classification System, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-25, primaryCompletionDateStruct date: 2024-06, completionDateStruct date: 2024-10, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Ain Shams University, class: OTHER, collaborators name: British University In Egypt, descriptionModule briefSummary: Different classifications to describe alveolar ridge defects have been published over the past years but no single classification has been developed concerning soft tissue volume around teeth or dental implants. Moreover, while several studies investigated the effect of various augmentation techniques and materials on soft tissue volume change and volume stability there is a real gap of knowledge regarding how to evaluate the available soft tissue volume and when to consider it sufficient or deficient which would definitely improve clinical decision making and treatment planing. Therefore, our primary aim was to assess the application of a novel classification system based on the correlation between buccal soft tissue volume and gingival biotypes and, also to assess the sensitivity of such novel method., conditionsModule conditions: Gingival Biotype, conditions: Soft Tissue, designModule studyType: OBSERVATIONAL, designInfo observationalModel: ECOLOGIC_OR_COMMUNITY, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 56, type: ESTIMATED, armsInterventionsModule interventions name: volume survey, outcomesModule primaryOutcomes measure: soft tissue volume - biotype correlation, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ahmed Hamdy, status: RECRUITING, city: Cairo, zip: 11234, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06348797, orgStudyIdInfo id: BHP01-01, briefTitle: Phase I Clinical Study of α-PD-L1/DLL3 CAR-T in Patients With R/R SCLC, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2025-07-31, completionDateStruct date: 2026-12-31, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Sichuan University, class: OTHER, collaborators name: Chengdu Brilliant Pharmaceutical Co., Ltd., descriptionModule briefSummary: A study to evaluate the safety and feasibility of α-PD-L1/4-1BB DLL3 Chimeric Antigen Receptor (CAR)-T (BHP01) in patients with Relapsed/Refractory Small Cell Lung Cancer (SCLC) and determine the appropriate CAR-T cell dose. Next, In dose expansion phase, patients were assign two groups with/without bridge radiotherapy., conditionsModule conditions: Small Cell Lung Cancer Extensive Stage, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 28, type: ESTIMATED, armsInterventionsModule interventions name: α-PD-L1/4-1BB DLL3 CAR-T (BHP01), outcomesModule primaryOutcomes measure: Dose-limiting toxicity (DLT), secondaryOutcomes measure: Objective Response Rate (ORR), secondaryOutcomes measure: Progression-free survival (PFS), secondaryOutcomes measure: Disease control rate (DCR), secondaryOutcomes measure: Duration of response (DOR), secondaryOutcomes measure: Overall-Survival (OS), secondaryOutcomes measure: CAR-T cell numbers, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06348784, orgStudyIdInfo id: 11, briefTitle: Screening for Ovarian Malignancy, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-01-01, primaryCompletionDateStruct date: 2023-01-01, completionDateStruct date: 2023-01-01, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Ain Shams Maternity Hospital, class: OTHER, descriptionModule briefSummary: Ovarian cancer is the second most common gynecologic malignancy. In 2008, it was the seventh leading cause of cancer deaths in women worldwide. Estimating the risk of malignancy is essential in the management of adnexal masses and several mathematical models and scoring systems have been developed to be used for discrimination between benign and malignant adnexal masses. Knowledge of the specific type of adnexal pathology before surgery is likely to improve patient triage with high accuracy, and it also makes it possible to optimize treatment. The correct identification of stage I cancer is particularly important, conditionsModule conditions: Early Detection of Ovarian Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 50, type: ACTUAL, armsInterventionsModule interventions name: Assesment of Different NEoplasias in the adenexa model, interventions name: Risk of malignancy index, interventions name: Histopathologic examination, outcomesModule primaryOutcomes measure: Sensitivity, specificity, positive predictive, and negative predictive value of Assessment of Different NEoplasias in the adneXa model for differentiating between benign and malignant ovarian tumors, eligibilityModule sex: FEMALE, minimumAge: 40 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: AinShams university maternity hospital, city: Cairo, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06348758, orgStudyIdInfo id: KAP towards AI, briefTitle: Knowledge, Attitudes, And Perceptions of a Group of Egyptian Dental Students Towards Artificial Intelligence, acronym: AIKnowledge, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2024-02-11, primaryCompletionDateStruct date: 2024-06-07, completionDateStruct date: 2024-08-07, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: In the context of this ongoing AI revolution, it is essential to ensure that current and future clinical practitioners are up to date regarding this technology's current state and potential. It is valuable to assess the current attitude of clinical dentists and undergraduate students in dentistry regarding the future role of AI.To the best of the author's knowledge, there is no study about Egyptian dental students' views and attitudes regarding the application of AI in dental practice. Therefore, this study aimed to evaluate the attitudes and perceptions of a group of dental students in Egypt towards AI., conditionsModule conditions: Health Knowledge, Attitudes, Practice, designModule studyType: OBSERVATIONAL, designInfo observationalModel: ECOLOGIC_OR_COMMUNITY, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 384, type: ESTIMATED, armsInterventionsModule interventions name: questionnaire, outcomesModule primaryOutcomes measure: knowledge, attitudes, and perceptions about artificial intelligence in Dentistry, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 25 Years, stdAges: ADULT, contactsLocationsModule locations facility: Cairo University- Faculty of Dentistry, city: Cairo, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False