hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06260345, orgStudyIdInfo id: CAPRICE, briefTitle: CommunautAry Pediatric bacteRial Infection in Intensive CarE Unit, acronym: CAPRICE, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2030-01-01, completionDateStruct date: 2030-01-01, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-02-15, sponsorCollaboratorsModule leadSponsor name: Association Clinique Thérapeutique Infantile du val de Marne, class: OTHER, collaborators name: GFRUP (Groupe Francophone de Réanimation et d'Urgences Pédiatrique), collaborators name: GPIP : Groupe de Pathologies Infectieuses Pédiatriques, collaborators name: Centre National de Référence des Streptocoques, collaborators name: Centre National de Référence des Pneumocoques, collaborators name: Centre National de Référence des Méningocoques et Haemophilus influenzae, collaborators name: Centre National de Référence des staphylocoques, collaborators name: Centre National de Référence des E. Coli, descriptionModule briefSummary: Severe bacterial infections are a worldwide scourge. However, the epidemiology of this type of infection varies over time. It is therefore essential to monitor them in order to prevent them more effectively. At this time, in France, no monitoring exists for this kind of infections., conditionsModule conditions: Hospitalized Children, conditions: Severe Infection, conditions: Invasive Bacterial Infection, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 3000, type: ESTIMATED, outcomesModule primaryOutcomes measure: number of pediatrics cases of severe communautary bacterial infections, primaryOutcomes measure: medical characterisation of children hospitalized for severe communautary bacterial infection case, secondaryOutcomes measure: Identify risk factors of serious infection, secondaryOutcomes measure: Identify predictive signs of severe cases in infected children., secondaryOutcomes measure: healthcare used for infected children, secondaryOutcomes measure: Type of complications, secondaryOutcomes measure: Patients outcome, secondaryOutcomes measure: treatment used during hospitalisation, secondaryOutcomes measure: Bacterial strain characterization, eligibilityModule sex: ALL, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Association Clinique Thérapeutique Infantile du val de Marne, status: RECRUITING, city: Créteil, zip: 94600, country: France, contacts name: Corinne Levy, MD, role: CONTACT, phone: 1 48 85 04 04, phoneExt: +33, email: corinne.levy@activ-france.fr, contacts name: Stéphane Béchet, MsC, role: CONTACT, phone: 1 48 85 04 04, phoneExt: +33, email: stephane.bechet@activ-france.fr, geoPoint lat: 48.78333, lon: 2.46667, hasResults: False
protocolSection identificationModule nctId: NCT06260332, orgStudyIdInfo id: INST UNM 2302, secondaryIdInfos id: 23-293, type: OTHER, domain: UNM HSC IRB, briefTitle: Physical Activity Intervention for the Improvement of Pain in Young, Hispanic Breast Cancer Survivors, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-10-20, primaryCompletionDateStruct date: 2024-08-30, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-02-15, sponsorCollaboratorsModule leadSponsor name: New Mexico Cancer Care Alliance, class: OTHER, collaborators name: University of New Mexico, descriptionModule briefSummary: This clinical trial tests whether increased activity throughout the day can improve the chronic pain and associated symptoms that breast cancer survivors may experience after surgery. Staying active is a key factor of one's physical, mental, and social health and well-being. Moving more could also reduce pain and associated stress, anxiety, or depression. Using a fitness tracker may help patients to move around more, whether or not they choose to exercise. Information gathered from this study may help researchers learn how the use of a Fitbit tracker with health coaching may improve physical activity and reduce pain in young, Hispanic breast cancer survivors., conditionsModule conditions: Breast Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 25, type: ESTIMATED, armsInterventionsModule interventions name: Supportive Care (Fitbit), outcomesModule primaryOutcomes measure: Recruitment rate (Feasibility), primaryOutcomes measure: Retention rate (Feasibility), primaryOutcomes measure: Adherence rate (Feasibility), primaryOutcomes measure: Incidence of adverse events, secondaryOutcomes measure: Change in chronic post-surgical pain, secondaryOutcomes measure: Change in physical activity, secondaryOutcomes measure: Change in health-related quality of life (hrQOL), eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: University of New Mexico Comprehensive Cancer Center, status: RECRUITING, city: Albuquerque, state: New Mexico, zip: 87106, country: United States, contacts name: Ellen R Wojcik, MBA-HCM, role: CONTACT, email: ewojcik@salud.unm.edu, contacts name: Cheryl A Sampson, MBA, role: CONTACT, email: ChSampson@salud.unm.edu, contacts name: Jacklyn M Nemunaitis, MD, role: PRINCIPAL_INVESTIGATOR, contacts name: Cindy K Blair, Ph.D., role: SUB_INVESTIGATOR, geoPoint lat: 35.08449, lon: -106.65114, hasResults: False
protocolSection identificationModule nctId: NCT06260319, orgStudyIdInfo id: C19-64, briefTitle: Decoding Developmental Disorders in Humams, acronym: devodecode, statusModule overallStatus: COMPLETED, startDateStruct date: 2019-01-01, primaryCompletionDateStruct date: 2024-01-01, completionDateStruct date: 2024-01-01, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-02-15, sponsorCollaboratorsModule leadSponsor name: Institut National de la Santé Et de la Recherche Médicale, France, class: OTHER_GOV, collaborators name: Imagine Institute, collaborators name: Commissariat A L'energie Atomique, descriptionModule briefSummary: The DEVO-DECODE project aims to align our currently limited knowledge currently limited knowledge of the genetic architecture of developmental with our more advanced knowledge of their "phenome".To this end, we aim to establish a homogeneous cohort of patients with with developmental disorders to identify new genetic variants genetic variants, and thus study the association between developmental and genetic variants. Secondary objectives are:2* Carry out WGS studies not only to refine exosomal sequencing data exome sequencing data, but above all to identify and validate non-coding non-coding DNA alterations, in both transcribed and non-transcribed transcribed or non-transcribed genomic domains* Develop precise preclinical models for functional studies of pathophysiological pathways, conditionsModule conditions: Genetic Diseases, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: RETROSPECTIVE, enrollmentInfo count: 720, type: ACTUAL, armsInterventionsModule interventions name: Whole genome sequencing and Genome-Epigenome-Phenome Associations, outcomesModule primaryOutcomes measure: Primary objectives, secondaryOutcomes measure: secondary objectives 1, secondaryOutcomes measure: secondary objectives 2, eligibilityModule sex: ALL, minimumAge: 1 Year, maximumAge: 90 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Institut Imagine, city: Paris, zip: 75015, country: France, geoPoint lat: 48.85341, lon: 2.3488, hasResults: False
protocolSection identificationModule nctId: NCT06260293, orgStudyIdInfo id: 4-2022-0208, briefTitle: The Effect of Post-operative Exercise in Gastric Cancer Patients: A Randomized Controlled Trial (RCT) Study, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-01-03, primaryCompletionDateStruct date: 2024-04-30, completionDateStruct date: 2024-04-30, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-02-15, sponsorCollaboratorsModule leadSponsor name: Yonsei University, class: OTHER, descriptionModule briefSummary: Medical advancements are enhancing the survival rates of individuals with gastric cancer. The growing population of gastric cancer survivors underscores the importance of managing treatment-related after-effects and side effects. Diminished physical function in cancer patients, particularly following gastric cancer surgery, is linked to increased mortality. The substantial decline in physical activity post-surgery contributes to a notable reduction in cardiorespiratory fitness and lower extremity muscle strength. Early postoperative exercise has demonstrated positive outcomes in colorectal cancer patients, facilitating early hospital discharge and supporting long-term recovery. However, there is a paucity of research on the efficacy of early postoperative exercise in the context of gastric cancer. Therefore, this study aims to evaluate the impact of early postoperative exercise on physical function following gastric cancer surgery., conditionsModule conditions: Gastric Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 52, type: ACTUAL, armsInterventionsModule interventions name: exercise, outcomesModule primaryOutcomes measure: Shorts Physical Performance Battery(SPPB), eligibilityModule sex: ALL, minimumAge: 19 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Department of Surgery, Yonsei University College of Medicine, city: Seoul, country: Korea, Republic of, geoPoint lat: 37.566, lon: 126.9784, hasResults: False
protocolSection identificationModule nctId: NCT06260280, orgStudyIdInfo id: 4, briefTitle: Chronic Sleep Deprivation and Changes in Cortical and Hippocampal Volume, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-02-26, primaryCompletionDateStruct date: 2024-05-26, completionDateStruct date: 2024-06-01, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-02-15, sponsorCollaboratorsModule leadSponsor name: Instituto Mexicano del Seguro Social, class: OTHER_GOV, descriptionModule briefSummary: Sleep is a physiological state that is essential for human performance, including academic, occupational, interpersonal, and psychological aspects. Sleep disruption or deprivation leads to a loss of psychomotor skills and an increased association with various diseases. Therefore, it is critical to assess how chronic sleep deprivation affects medical residents who work long shifts, including those assigned during their training., conditionsModule conditions: Sleep Deprivation, conditions: Hippocampal Atrophy, conditions: Cortical Irregularity, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 37, type: ESTIMATED, armsInterventionsModule interventions name: Cerebral Nuclear Magnetic Resonance, outcomesModule primaryOutcomes measure: Change in Hippocampal volumetry., primaryOutcomes measure: Change in cortical volumetry, eligibilityModule sex: ALL, minimumAge: 24 Years, maximumAge: 30 Years, stdAges: ADULT, contactsLocationsModule locations facility: Unidad Medica de Alta Especialidad No. 1, Bajío, city: Leon, state: Guanajuato, zip: 37260,, country: Mexico, geoPoint lat: 21.12908, lon: -101.67374, hasResults: False
protocolSection identificationModule nctId: NCT06260267, orgStudyIdInfo id: 000417, briefTitle: A Phase 1b Proof-of-concept Trial Exploring the Effects of FE 999322 and FE 999324 in Adults With Mild to Moderate Ulcerative Colitis, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-12, primaryCompletionDateStruct date: 2025-09-15, completionDateStruct date: 2025-09-15, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Ferring Pharmaceuticals, class: INDUSTRY, descriptionModule briefSummary: To explore the safety of FE 999322 (microbiota suspension) and FE 999324 (microbiota capsule) versus placebo in subjects with active mild to moderate ulcerative colitis (UC)., conditionsModule conditions: Ulcerative Colitis, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, enrollmentInfo count: 90, type: ESTIMATED, armsInterventionsModule interventions name: Microbiota suspension, interventions name: Microbiota capsule, interventions name: Placebo suspension, interventions name: Placebo capsule, outcomesModule primaryOutcomes measure: Treatment-emergent adverse events from baseline to week 52, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ferring Investigational Site, status: RECRUITING, city: North Little Rock, state: Arkansas, zip: 72117, country: United States, contacts name: Global Clinical Compliance, role: CONTACT, geoPoint lat: 34.76954, lon: -92.26709, locations facility: Ferring Investigational Site, status: RECRUITING, city: Jacksonville, state: Florida, zip: 32256, country: United States, contacts name: Global Clinical Compliance, role: CONTACT, geoPoint lat: 30.33218, lon: -81.65565, locations facility: Ferring Investigational Site, status: RECRUITING, city: Oklahoma City, state: Oklahoma, zip: 73102, country: United States, contacts name: Global Clinical Compliance, role: CONTACT, geoPoint lat: 35.46756, lon: -97.51643, hasResults: False
protocolSection identificationModule nctId: NCT06260241, orgStudyIdInfo id: ShaikhZayedH, briefTitle: Gain in Stretched Penile Length After Phalloplasty With & Without Penile Traction in Children., statusModule overallStatus: RECRUITING, startDateStruct date: 2023-01-01, primaryCompletionDateStruct date: 2025-01-01, completionDateStruct date: 2025-01-01, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-02-15, sponsorCollaboratorsModule leadSponsor name: Shaikh Zayed Hospital, Lahore, class: OTHER, descriptionModule briefSummary: The goal of this Randomized Controlled Trial is to assess the gain in stretched penile length after phalloplasty with \& without penile traction in children of age group 4 to 13 years presenting in hospital with the complaint of concealed penis.The main question\[s\] it aims to answer is:• Gain in stretched penile length after phalloplasty with and without penile traction in children., conditionsModule conditions: Concealed Penis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized Control Trial, primaryPurpose: OTHER, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 70, type: ESTIMATED, armsInterventionsModule interventions name: Traction Dressing, interventions name: Without Traction Dressing, outcomesModule primaryOutcomes measure: The gain in stretched penile length (SPL), eligibilityModule sex: MALE, minimumAge: 4 Years, maximumAge: 13 Years, stdAges: CHILD, contactsLocationsModule locations facility: Sheikh Zayed Hospital, status: RECRUITING, city: Lahore, state: Punjab, country: Pakistan, contacts name: ADEEL AHMED, MBBS MS, role: CONTACT, phone: 00923491467739, email: numberdar12@gmail.com, geoPoint lat: 31.558, lon: 74.35071, hasResults: False
protocolSection identificationModule nctId: NCT06260228, orgStudyIdInfo id: STUDY02002270, briefTitle: HOme-Based Self-management and COgnitive Training CHanges Lives (HOBSCOTCH)-Parkinson's Disease (HOBSCOTCH-Parkinson's), acronym: HOBSCOTCH-PD, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-05, primaryCompletionDateStruct date: 2024-08-01, completionDateStruct date: 2024-11-30, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-02-15, sponsorCollaboratorsModule leadSponsor name: Dartmouth-Hitchcock Medical Center, class: OTHER, descriptionModule briefSummary: The goal of this pilot study is to assess the feasibility of adapting and delivering the existing home-based epilepsy self-management intervention, HOBSCOTCH, for people with Parkinson's Disease (PD)The main questions it aims to answer are:1. Can the current HOBSCOTCH program be adapted for people with PD?2. Will people with PD experience improved quality of life similar to that found in people with epilepsy after participating in the HOBSCOTCH program?Participants will be asked to:* attend nine, one-hour virtual (online and/or by telephone) HOBSCOTCH-PD sessions with a one-on-one certified HOBSCOTCH-PD coach* complete a brief clinical questionnaire about their diagnosis of PD* complete two questionnaires before and after the HOBSCOTCH-PD sessions about their quality of life and about memory and thinking processes* keep a short daily diary about their PD symptoms and use of the self-management strategies taught in the HOBSCOTCH-PD program* complete a brief Satisfaction Survey after the entire HOBSCOTCH-PD program, conditionsModule conditions: Parkinson Disease, conditions: Cognitive Dysfunction, conditions: Memory Disorders, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 5, type: ESTIMATED, armsInterventionsModule interventions name: HOme-Based Self-management and COgnitive Training CHanges lives (HOBSCOTCH), outcomesModule primaryOutcomes measure: Change in quality of life as measured by comparing PDQ-39 (Parkinson's Disease Questionnaire) scores pre- and post-HOBSCOTCH-PD intervention., primaryOutcomes measure: Change in subjective cognition as measured by comparing Neuro-QOL Item Bank v2.0 Cognitive Function scores pre- and post-HOBSCOTCH-PD intervention., eligibilityModule sex: ALL, minimumAge: 30 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Dartmouth-Hitchcock, status: RECRUITING, city: Lebanon, state: New Hampshire, zip: 03756, country: United States, contacts name: Sarah J Kaden, role: CONTACT, phone: 603-540-5824, email: sarah.j.kaden@hitchcock.org, geoPoint lat: 43.64229, lon: -72.25176, hasResults: False
protocolSection identificationModule nctId: NCT06260202, orgStudyIdInfo id: 308.273, briefTitle: Nutrition Under Noninvasive Ventilation, acronym: NUTRINIV, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-05-31, completionDateStruct date: 2024-05-31, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-02-16, sponsorCollaboratorsModule leadSponsor name: Università degli Studi del Piemonte Orientale "Amedeo Avogadro", class: OTHER, descriptionModule briefSummary: Even though nutrition is a fundamental component of Intensive care unit (ICU) therapy, critically ill patients are frequently malnourished, a factor well known for its strong association with a higher risk of complications, prolonged ICU/hospital length of stay, and greater ICU readmission and mortality rates. Noninvasive ventilation (NIV) use has increased considerably over the past twenty years, making this supportive technique a keystone of acute respiratory failure (ARF) treatment. In this setting, respiratory support is provided through an interface, usually a mask or a helmet, that frequently represents an important obstacle to nutrition delivery, making oral intake impossible and posing the necessity to start enteral (EN) or parenteral nutrition (PN). Moreover, while critical care guidelines regarding nutritional management of patients receiving mechanical ventilation (MV) are well established, data and recommendations about the appropriate nutritional support to patients in NIV are still very limited. Due to this limited data, we want to describe characteristics and nutritional management of patients undergoing NIV in ICU, and to evaluate the difference between the mean caloric and protein intake of these patients and the recommended caloric and protein target for critically ill patients. Secondarily, we want to evaluate the difference of the caloric and protein intake among groups of patients undergoing different nutritional modality and to assess potential associations of the nutritional characteristics with patient outcomes., conditionsModule conditions: Noninvasive Ventilation, conditions: Nutrition Therapy, conditions: Respiratory Insufficiency, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 112, type: ESTIMATED, outcomesModule primaryOutcomes measure: Caloric and protein gap, secondaryOutcomes measure: Nutrition modalities outcomes, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06260189, orgStudyIdInfo id: Soh-Med-24-01-02MD, briefTitle: Assessment Of Serum And Tissue Levels Of Cold-Inducible RNA-Binding Protein In Patients With Lichen Planus, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02, primaryCompletionDateStruct date: 2025-02, completionDateStruct date: 2025-10, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-02-15, sponsorCollaboratorsModule leadSponsor name: Sohag University, class: OTHER, descriptionModule briefSummary: Lichen planus (LP) is a chronic inflammatory mucocutaneous disease of unknown etiology.Pathogenesis of LP is not completely understood, but it's considered a T-cell-mediated autoimmune disease. Cold-inducible RNA binding protein (CIRP or CIRBP) is a member of the glycine-rich RNA-binding protein family, Recent studies proved that CIRP acts as a tumor promoter through its actions on different cellular proliferation levels, Recently, the role of the damage associated molecular proteins and cytokines was highlighted in the pathogenesis of many disorders including psoriasis, alopecia areata, vitiligo, rheumatoid arthritis, other autoimmune diseases as well as several types of cancer. The aim of this study is to compare serum and tissue levels of CIRP in patients with LP and healthy controls., conditionsModule conditions: Assessment, Self, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Assessment of cold-inducible RNA binding protein levels in serum and tissue, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Aya Ahmed Elsayed, status: RECRUITING, city: Sohag, zip: 82511, country: Egypt, contacts name: Aya A Elsayed, Msc, role: CONTACT, phone: 00201060094631, phoneExt: Egypt, email: aya_shando@yahoo.com, geoPoint lat: 26.55695, lon: 31.69478, hasResults: False