hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06284083, orgStudyIdInfo id: Cumhuriyet University Hospital, briefTitle: Measuring Various Variables in Obstructive Sleep Apnea, acronym: OUAS, statusModule overallStatus: COMPLETED, startDateStruct date: 2018-12-18, primaryCompletionDateStruct date: 2021-01-15, completionDateStruct date: 2022-02-07, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Cumhuriyet University, class: OTHER, descriptionModule briefSummary: This study included 90 volunteer Obstructive Sleep Apnea Syndrome patients. Only 7 mL blood samples collected from patients. Some biochemicals parameters analyzed in blood serum/plasma., conditionsModule conditions: Obstructive Sleep Apnea-hypopnea Syndrome, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The study group consisted of 90 newly diagnosed OSAS patients who were admitted to the Clinic for Chest Diseases of the Research and Practice Hospital of Sivas Cumhuriyet University Faculty of Medicine. For the definitive diagnosis of OSAS, the patients were hospitalized overnight in the Sleep Center and polysomnography test was performed. OSAS patients, who were randomly selected without discrimination in terms of age and gender, were connected to the PSG device for one night and various measurements were taken and the values were recorded. The apnea/hypopnea index (AHI) was defined as the sum of the apnea and hypopnea number per hour of sleep. Volunteer patients were grouped into three based on apnea-hypopnea index (AHI) scores: mild OSAS (n=30; 5 ≤ AHI ≤ 13.70), moderate (n=30; 15.80 ≤ AHI ≤ 26.60) and severe (n=30; 34.10 ≤ AHI ≤ 86.30). The mean SpO2 percentages of the PSG device were measured from the fingertip with a system-defined pulse oximeter., primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 90, type: ACTUAL, armsInterventionsModule interventions name: taking a blood sample, outcomesModule primaryOutcomes measure: Agmatine, telomerase and trace element levels in blood serum vary depending on disease severity., secondaryOutcomes measure: Polysomnographic measurement, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 74 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Sivas Cumhuriyet University, city: Sivas, state: Centre, zip: 58140, country: Turkey, geoPoint lat: 39.74833, lon: 37.01611, hasResults: False
protocolSection identificationModule nctId: NCT06284070, orgStudyIdInfo id: 202433, briefTitle: Application of FAPI and FDG PET Imaging in Patients With Different Types of Cancer, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2029-12-31, completionDateStruct date: 2029-12-31, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, class: OTHER, descriptionModule briefSummary: Cancer associated fibroblasts (CAFs) can promote tumor cell proliferation, migration, invasion, and angiogenesis through immunosuppressive effects and the production of mediators, thereby promoting tumor growth and progression. The characteristic of CAFs is high expression of fibroblast activation protein (FAP). In approximately 90% of epithelial derived tumors, FAP is highly overexpressed on the membrane of CAFs. Contrary to CAFs, FAP expression is lower or absent in normal tissues. Therefore, FAP inhibitors (FAPI) targeting FAP can overcome the limitations of 18F-2-fluoro.2-deoxy-D-glucose fluorodeoxyglucose(18F-FDG) PET imaging. But like 18F-FDG, wound healing, fibrosis, and inflammation can also uptake FAPI.. Therefore, a comparison of the performance of 18F-FDG and 18F-FAPI PET imaging in diagnosing primary and metastatic lesions of various types of cancer is conducted to evaluate the potential value of these new radiopharmaceuticals as effective alternatives to 18F-FDG, highlighting their advantages and limitations., conditionsModule conditions: Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 2000, type: ESTIMATED, outcomesModule primaryOutcomes measure: Diagnostic efficacy, secondaryOutcomes measure: SUV, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Department of Nuclear Medicine, Daping Hospital of Army Medical University, status: RECRUITING, city: Chongqing, state: Chongqing, zip: 400010, country: China, contacts name: Xiao Chen, Ph.D, role: CONTACT, phone: 15922970174, email: xiaochen229@foxmail.com, contacts name: Xiao Chen, Ph.D, role: PRINCIPAL_INVESTIGATOR, contacts name: Jinju Sun, MSc, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 29.56278, lon: 106.55278, hasResults: False
protocolSection identificationModule nctId: NCT06284057, orgStudyIdInfo id: CopperHealthCentre3, briefTitle: Lower Silesia Culotte Bifurcation Registry (LSCBR)., acronym: LSCBR, statusModule overallStatus: RECRUITING, startDateStruct date: 2013-04-01, primaryCompletionDateStruct date: 2028-04-01, completionDateStruct date: 2028-04-01, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Regional Cardiology Center, The Copper Health Centre (MCZ),, class: OTHER, collaborators name: Department of Cardiology, Provincial Specialized Hospital in Legnica, 59-200 Legnica, Poland., descriptionModule briefSummary: The study aimed to evaluate the outcomes of bifurcation PCI using two techniques (Culotte vs. DK-Culotte) using data from a retrospective analysis., conditionsModule conditions: Safety Issues, conditions: Efficacy, Self, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 400, type: ESTIMATED, armsInterventionsModule interventions name: Bifurcation PCI with two stent technique Culotte Technique or Double Kiss (DK) Culotte, outcomesModule primaryOutcomes measure: Target lesion failure (TLF), secondaryOutcomes measure: MACE, otherOutcomes measure: Stent thrombosis, otherOutcomes measure: Stent restenosis, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Department of Cardiology, Provincial Specialized Hospital in Legnica,, status: RECRUITING, city: Legnica, state: Lower Silesia, zip: 59-220, country: Poland, contacts name: Mateusz Barycki, M.D, role: CONTACT, phone: +48767211446, email: mateusz.barycki@gmail.com, contacts name: Piotr Rola, M.D. Ph.D, role: CONTACT, phone: +48767211446, email: piotr.rola@gmail.com, contacts name: Mateusz Barycki, MD, role: PRINCIPAL_INVESTIGATOR, contacts name: Piotr Rola, MD PhD, role: SUB_INVESTIGATOR, geoPoint lat: 51.21006, lon: 16.1619, locations facility: Department of Cardiology, The Copper Health Centre (MCZ), status: RECRUITING, city: Lubin, state: Lower Silesia, zip: 59-300, country: Poland, contacts name: Adrian Włodarczak, Assoc Prof., role: CONTACT, phone: +48768460300, email: wlodarczak.adrian@gmail.com, contacts name: Szymon Włodarczak, MD, role: CONTACT, phone: +4876 846 03 00, email: wlodarczak.szy@gmail.com, contacts name: Adrian Włodarczak, Assoc Prof., role: PRINCIPAL_INVESTIGATOR, contacts name: Szymon Włodarczak, MD, role: SUB_INVESTIGATOR, geoPoint lat: 51.40089, lon: 16.20149, hasResults: False
protocolSection identificationModule nctId: NCT06284044, orgStudyIdInfo id: NIHR204885, briefTitle: Facilitating Safe Transition to Home for Preterm Infants - a National Database Study, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-12-01, primaryCompletionDateStruct date: 2024-11-30, completionDateStruct date: 2024-11-30, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: University Hospitals of Derby and Burton NHS Foundation Trust, class: OTHER, descriptionModule briefSummary: Preterm infants (i.e. born before 37 completed weeks of pregnancy) often require additional care and are admitted to neonatal units. Readiness for discharge home typically requires a level of physiological maturity, such that an infant is: 1) able to breathe spontaneously without additional support; 2) able to maintain body temperature; 3) able to take all nutritional requirements orally; 4) weighs ≥1700 grams and is consistently gaining weight.Staying in the hospital longer than necessary can be detrimental to infants, stressful for families, and costly to the NHS. Reducing the length of stay by just one day would be meaningful to parents and could save the UK National Health Service (NHS) almost £25million per year. Currently little is known about whether, how long and why preterm infants stay in hospital beyond the point at which they are physiologically ready for discharge.This study will use data from babies' medical records from the whole of England and Wales to identify the age and postmenstrual age when preterm infants reach each of the physiological barriers to discharge and identify which physiological discharge barrier requires preterm infants to remain in hospital the longest. The study will quantify the difference between the time preterm infants become physiologically ready for discharge and actual discharge home and describe factors associated with extended stays., conditionsModule conditions: Premature Birth, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: OTHER, enrollmentInfo count: 250000, type: ESTIMATED, outcomesModule primaryOutcomes measure: Age and postmenstrual age when each of three physiological barriers are reached, primaryOutcomes measure: Final barrier to discharge home, secondaryOutcomes measure: Number of days in hospital after surpassing all physiological discharge barriers, eligibilityModule sex: ALL, minimumAge: 22 Weeks, maximumAge: 36 Weeks, stdAges: CHILD, contactsLocationsModule locations facility: University Hospitals of Derby and Burton, status: RECRUITING, city: Derby, state: Derbyshire, zip: DE22 3DT, country: United Kingdom, contacts name: Janine Abramson, BSc Hon, role: CONTACT, phone: 01332 724690, email: janine.abramson@nottingham.ac.uk, geoPoint lat: 52.92277, lon: -1.47663, hasResults: False
protocolSection identificationModule nctId: NCT06284031, orgStudyIdInfo id: Brachy Study, briefTitle: Cervical Cancer Brachytherapy With Interstitial Needles in 3 Fractions, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-06-26, primaryCompletionDateStruct date: 2026-06, completionDateStruct date: 2026-12, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: National University Hospital, Singapore, class: OTHER, descriptionModule briefSummary: Aim To determine the feasibility and safety of 3 fractions of high dose rate (HDR) brachytherapy with interstitial needles for cervical cancer in the outpatient settingPrimary objective To determine the clinical outcome (2-yr local control rate, loco-regional control rate, progression free survival and overall survival)Secondary objective To determine the long-term toxicities of this regimen based on CTCAE v5, conditionsModule conditions: Cervical Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 56, type: ESTIMATED, armsInterventionsModule interventions name: 3 fractions HDR brachytherapy, outcomesModule primaryOutcomes measure: Local control rate, primaryOutcomes measure: Loco-regional control rate, primaryOutcomes measure: Progression-free survival (PFS), primaryOutcomes measure: Overall survival (OS), secondaryOutcomes measure: Long term toxicities, eligibilityModule sex: FEMALE, minimumAge: 21 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: National University Hospital, status: RECRUITING, city: Singapore, zip: 119074, country: Singapore, contacts name: Fatin Aliyah, BSc, role: CONTACT, phone: +6581005851, email: fatin_hussin@nuhs.edu.sg, contacts name: Syadwa Abdul Shukor, MD, role: SUB_INVESTIGATOR, contacts name: Yiat Horng Leong, MD, role: SUB_INVESTIGATOR, contacts name: Shing Fung Lee, MD, role: SUB_INVESTIGATOR, contacts name: Michelle Tseng, MD, role: SUB_INVESTIGATOR, geoPoint lat: 1.28967, lon: 103.85007, hasResults: False
protocolSection identificationModule nctId: NCT06284018, orgStudyIdInfo id: postnatal low back pain, briefTitle: Effect of Progressive Muscle Relaxation Exercises Versus Pilates Exercises on Postnatal Low Back Pain, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-02-24, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: This study was conducted to compare between the effect of progressive muscle relaxation exercises and the effect of pilates exercises on postnatal low back pain, conditionsModule conditions: Low Back Pain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: intervention The design of the study was randomized controlled study. The patients were divided randomly into two equal groups (A\&B). Group A consisted of thirty postnatal women. They were treated by progressive muscle relaxation exercises three times per week for 4 weeks. Group B consisted of thirty postnatal women. They were treated by pilates exercises three times per week for 4 weeks., primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Progressive Muscle Relaxation Exercises, interventions name: Pilates Exercises, outcomesModule primaryOutcomes measure: Pressure Algometer, secondaryOutcomes measure: Oswestry Disability Index, eligibilityModule sex: FEMALE, minimumAge: 25 Years, maximumAge: 35 Years, stdAges: ADULT, contactsLocationsModule locations facility: faculty of physical therapy: Cairo university, city: Giza, zip: 12662, country: Egypt, geoPoint lat: 30.00808, lon: 31.21093, hasResults: False
protocolSection identificationModule nctId: NCT06284005, orgStudyIdInfo id: MOTU ATP - Studio clinico, briefTitle: Multicentre Interventional Pilot Study on the Evaluation of the Functionality, Safety and Reliability of a New Robotic Prosthesis for the Lower Limb at the Transfemoral Level, acronym: MOTU-ATP, statusModule overallStatus: COMPLETED, startDateStruct date: 2020-07-27, primaryCompletionDateStruct date: 2022-11-10, completionDateStruct date: 2022-12-22, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Fondazione Don Carlo Gnocchi Onlus, class: OTHER, descriptionModule briefSummary: The goal of this multicenter interventional pilot is to verify the functionality of a prosthesis for trans-femoral amputees.The main question it aims to answer are:* Is to verify the technical functionality, safety and reliability of the propulsive lower limb prosthesis prototype, with active ankle, so as to provide indications regarding the technical and functional developments to be implemented in the finalization of the device.* Provide an indication of the functional effectiveness of the device and its satisfaction by patients.Participants will perform:* walking tests inside parallel bars on flat and/or inclined terrain;* walking tests on treadmill;* stair climbing/descent tests., conditionsModule conditions: Amputation, conditions: Amputation; Traumatic, Leg, Lower, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: DEVICE_FEASIBILITY, maskingInfo masking: NONE, enrollmentInfo count: 4, type: ACTUAL, armsInterventionsModule interventions name: WRL ATP, outcomesModule primaryOutcomes measure: ad hoc check-list Adverse Event, primaryOutcomes measure: ad hoc check-list Adverse Event, primaryOutcomes measure: ad hoc check-list Adverse Event, primaryOutcomes measure: ad hoc check-list Adverse Event, primaryOutcomes measure: ad hoc check-list Adverse Event, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: IRCCS Fondazione Don Carlo Gnocchi, city: Firenze, state: FI, zip: 50143, country: Italy, geoPoint lat: 43.77925, lon: 11.24626, hasResults: False
protocolSection identificationModule nctId: NCT06283992, orgStudyIdInfo id: 2024p000095, secondaryIdInfos id: K23MD016439, type: NIH, link: https://reporter.nih.gov/quickSearch/K23MD016439, briefTitle: Digital Health Navigation for Latino Patients With Type II Diabetes, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-31, primaryCompletionDateStruct date: 2026-05-31, completionDateStruct date: 2027-05-31, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Brigham and Women's Hospital, class: OTHER, collaborators name: National Institute on Minority Health and Health Disparities (NIMHD), descriptionModule briefSummary: The goal of this clinical trial is to learn about digital literacy training in adult, Latino patient with type II diabetes. The main question it aims to answer is: Can providing digital literacy training during a hospital admission can help patients with their after-hospital care by using the patient portal and telehealth? Participants will receive digital literacy training by a digital navigator that focuses on the main patient portal functions. Researchers will compare patients who receive digital literacy training to those who receive standard of care (educational sheet) to see if it impacts their use of the patient portal after discharge., conditionsModule conditions: Type 2 Diabetes, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Researchers will compare effectiveness between two arms: 1) patient education using a digital navigator on using digital tools after discharge and 2) usual care (educational sheet)., primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: DOUBLE, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 84, type: ESTIMATED, armsInterventionsModule interventions name: Digital Navigation, outcomesModule primaryOutcomes measure: Proportion of Participants Who Login to the Portal, secondaryOutcomes measure: Proportion of Participants that Perform Distinct Portal Functions, secondaryOutcomes measure: Proportion of participants that complete a telehealth, secondaryOutcomes measure: Proportion of participants that are re-admitted, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Brigham and Women's Hospital, status: RECRUITING, city: Boston, state: Massachusetts, zip: 02120, country: United States, contacts name: Jorge A Rodriguez, MD, role: CONTACT, geoPoint lat: 42.35843, lon: -71.05977, hasResults: False
protocolSection identificationModule nctId: NCT06283979, orgStudyIdInfo id: 199723, briefTitle: A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers., acronym: BLADE OPU2, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-12-01, completionDateStruct date: 2025-12-01, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: Biocomposites Ltd, class: INDUSTRY, collaborators name: MCRA, descriptionModule briefSummary: The purpose of this trial is to assess the safety, tolerability and between-group effect size of STIMULAN VG (with debridement) and a course of systemic antibiotics to standard of care (debridement and systemic antibiotics only) for the treatment of osteomyelitis associated stage IV pressure ulcers., conditionsModule conditions: Pressure Ulcer, Stage IV, conditions: Osteomyelitis, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: STIMULAN VG, interventions name: Standard of Care, outcomesModule primaryOutcomes measure: Individual patient success and findings at the 8 week follow-up visit, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06283914, orgStudyIdInfo id: BIO-2024-0011, briefTitle: Imputation of Arterial Oxygen Partial Pressures Using Pulse Oximetry, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-08-01, completionDateStruct date: 2024-09-01, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: American University of Beirut Medical Center, class: OTHER, descriptionModule briefSummary: The goal of this is prospective cohort study is to to study the relationship between PaO2 and SpO2 in the overall population undergoing general anesthesia in the OT. Secondary aims include studying the relationship between PaO2 and SpO2 in elderly and obese patients undergoing general anesthesia in the OT, validating the derivation of PaO2 from SpO2 using formulas derived by Rice et al. (2009), Pandharipande et al. (2009), and Gadrey et al. (2019) in patients undergoing general anesthesia in the OT, and, if the derivation formulas were not valid, to derive a formula for patients undergoing general anesthesia in the OT.The included blood samples are arterial blood sample collected for ABGs analysis through either an arterial catheter or an arterial blood puncture in adult patients (Age \>18 years) undergoing general anesthesia regardless of the acuity of the surgery (elective, emergency, or lifesaving), the hemodynamic stability of the patient, or the comorbidities. Patients undergoing cardiac or thoracic surgeries will be excluded., conditionsModule conditions: Oxygen Saturation, conditions: Respiratory Distress Syndrome, conditions: Anesthesia, General, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 300, type: ESTIMATED, outcomesModule primaryOutcomes measure: PaO2, otherOutcomes measure: SpO2, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False