hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06333002, orgStudyIdInfo id: PI24/00325, briefTitle: Machine Learning Model to Predict Outcome and Duration of Mechanical Ventilation in Acute Hypoxemic Respiratory Failure, acronym: MEMORIAL, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-03-19, primaryCompletionDateStruct date: 2026-05-30, completionDateStruct date: 2026-05-30, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Dr. Negrin University Hospital, class: OTHER, descriptionModule briefSummary: Acute hypoxemic respiratory failure (AHRF) is the most common cause of admission in the intensive care units (UCIs) worldwide. We will assess the value of machine learning (ML) techniques for early prediction of ICU death and prolonged duration (\>7 days) of mechanical ventilation (MV) in 1,241 patients enrolled in the PANDORA (Prevalence AND Outcome of acute Respiratory fAilure) Study in Spain. The study was registered with ClinicalTrials.gov (NCT03145974). Our aim is to evaluate the minimum number of variables models using logistic regression and four supervised ML algorithms: Random Forest, Extreme Gradient Boosting, Support Vector Machine and Multilayer Perceptron., conditionsModule conditions: Acute Hypoxemic Respiratory Failure, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 1241, type: ESTIMATED, armsInterventionsModule interventions name: machine learning analysis, outcomesModule primaryOutcomes measure: ICU mortality, secondaryOutcomes measure: MV duration, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 100 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hospital General Universitario de Ciudad Real, city: Ciudad Real, zip: 13005, country: Spain, geoPoint lat: 38.98626, lon: -3.92907, locations facility: Hospital Virgen de La Luz, city: Cuenca, zip: 16002, country: Spain, geoPoint lat: 40.06667, lon: -2.13333, locations facility: Hospital Universitario La Paz, city: Madrid, zip: 28046, country: Spain, geoPoint lat: 40.4165, lon: -3.70256, locations facility: Hospital Universitario Puerta de Hierro, city: Madrid, zip: 28222, country: Spain, geoPoint lat: 40.4165, lon: -3.70256, locations facility: Hospital Universitario Virgen de Arrixaca, city: Murcia, zip: 3012, country: Spain, geoPoint lat: 37.98704, lon: -1.13004, locations facility: Hospital Universitario NS de Candelaria, city: Santa Cruz De Tenerife, zip: 38010, country: Spain, geoPoint lat: 28.46824, lon: -16.25462, locations facility: Hospital Cinico de Valencia, city: Valencia, zip: 46010, country: Spain, geoPoint lat: 39.46975, lon: -0.37739, locations facility: Hospital Universitario Rio Hortega, city: Valladolid, zip: 47012, country: Spain, geoPoint lat: 41.65518, lon: -4.72372, hasResults: False
protocolSection identificationModule nctId: NCT06332989, orgStudyIdInfo id: N22.129, briefTitle: Stroke Triage Optimization by Ambulance Paramedics in the Pre-hospital Setting, acronym: STROKE-APP, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-01, primaryCompletionDateStruct date: 2027-02-01, completionDateStruct date: 2027-02-01, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Leiden University Medical Center, class: OTHER, collaborators name: Alrijne Ziekenhuis Leiderdorp, collaborators name: Groene Hart Ziekenhuis, collaborators name: Medical Center Haaglanden, collaborators name: HagaZiekenhuis, collaborators name: Reinier de Graaf Groep, collaborators name: Regionale Ambulance Voorziening Hollands Midden, descriptionModule briefSummary: There are everal scales designed to help ambulance paramedics to identify a patient with a stroke and activate a stroke code. These scales were never tested in the field in a large unselected patient sample. We aim to perform an in-the field head tot head comparison of all published stroke scales designed to be used by ambulance paramedics, conditionsModule conditions: Stroke, Acute, conditions: Pre-hospital Triage, conditions: Stroke Treatment, conditions: Stroke Code, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 3000, type: ESTIMATED, armsInterventionsModule interventions name: stroke-APP, outcomesModule primaryOutcomes measure: final diagnosis, primaryOutcomes measure: treated with reperfusion therapy, primaryOutcomes measure: additional investigations, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Leiden University medical center, status: RECRUITING, city: Leiden, country: Netherlands, contacts name: Nyika D Kruyt, MD. PhD, role: CONTACT, phone: 0031-715262139, email: n.d.kruyt@lumc.nl, geoPoint lat: 52.15833, lon: 4.49306, hasResults: False
protocolSection identificationModule nctId: NCT06332976, orgStudyIdInfo id: IEO 1521, briefTitle: PrefeRences And ChemoTherapy In Breast Cancer patiEnts, acronym: PRACTICE, statusModule overallStatus: RECRUITING, startDateStruct date: 2021-06-04, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: European Institute of Oncology, class: OTHER, descriptionModule briefSummary: The aim of the present study is to ask women treated with adjuvant or neoadjuvant chemotherapy for breast cancer what survival benefit would justify the treatment.The benefit should be evaluated in terms of Survival rate trade off and Survival time trade off value. The analyses will be conducted into three different groups of patients to value the survival benefit expected:1. before to start the chemotherapy2. during chemotherapy3. after the end of chemotherapy, conditionsModule conditions: Female Breast Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 450, type: ESTIMATED, armsInterventionsModule interventions name: Completion of questionnaires, outcomesModule primaryOutcomes measure: Percentage of risk reduction needed to consider adjuvant or neoadjuvant chemotherapy worthwhile, primaryOutcomes measure: Prolonged survival time gain needed to consider CT worthwhile, secondaryOutcomes measure: Behavior assessment, secondaryOutcomes measure: Reaction to uncertain situations assessment, secondaryOutcomes measure: Regret and disappointment assessment, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: European Institute of Oncology, status: RECRUITING, city: Milan, zip: 20141, country: Italy, contacts name: Emilia Montagna, MD, role: CONTACT, phone: +390257489970, email: emilia.montagna@ieo.it, geoPoint lat: 45.46427, lon: 9.18951, hasResults: False
protocolSection identificationModule nctId: NCT06332950, orgStudyIdInfo id: MA-SCLC-II-015, briefTitle: Safety and Efficacy of Adebrelimab Plus Irinotecan Liposome (II) With or Without Famitinib in ES-SCLC Pre-treated With Immunotherapy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2027-04-01, completionDateStruct date: 2027-04-01, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Baohui Han, class: OTHER, descriptionModule briefSummary: This is an open-label, randomized, multi-cohort, multi-center, phase Ib/II study to evaluate the safety and efficacy of Adebrelimab plus Irinotecan Liposome (II) with or without Famitinib in patients with extensive-stage small cell lung cancer (ES-SCLC) pre-treated with immune checkpoint inhibitor(s)., conditionsModule conditions: Extensive-stage Small-cell Lung Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE1, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Adebrelimab, Irinotecan Liposome (II), interventions name: Adebrelimab, Irinotecan Liposome (II), Famitinib, outcomesModule primaryOutcomes measure: 6-month progression-free survival, secondaryOutcomes measure: Safety, secondaryOutcomes measure: Objective response rate, secondaryOutcomes measure: Progression-free survival, secondaryOutcomes measure: Overall survival, secondaryOutcomes measure: Disease control rate, secondaryOutcomes measure: Duration of response, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Shanghai Chest Hospital, city: Shanghai, country: China, contacts name: Baohui Han, M.D, role: CONTACT, email: 18930858216@163.com, geoPoint lat: 31.22222, lon: 121.45806, hasResults: False
protocolSection identificationModule nctId: NCT06332937, orgStudyIdInfo id: H-2102-079-1197, briefTitle: Breast Reconstruction, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2021-02-22, primaryCompletionDateStruct date: 2023-12-15, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Seoul National University Hospital, class: OTHER, descriptionModule briefSummary: Complications following postmastectomy breast reconstruction can compromise surgical outcomes and lead to significant morbidity. The aim of this study was to determine factors associated with complication following two-stage implant-based reconstruction, conditionsModule conditions: Breast Implant; Complications, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 5000, type: ESTIMATED, armsInterventionsModule interventions name: postmastectomy breast reconstruction, outcomesModule primaryOutcomes measure: Infection, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Seoul National University Hospital, city: Seoul, zip: 03080, country: Korea, Republic of, geoPoint lat: 37.566, lon: 126.9784, hasResults: False
protocolSection identificationModule nctId: NCT06332924, orgStudyIdInfo id: 2023/19, briefTitle: Primipara Pregnant Women and Motivational Interview, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-07-01, completionDateStruct date: 2024-08-01, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Saglik Bilimleri Universitesi, class: OTHER, descriptionModule briefSummary: The first birth is the most important moment a woman experiences in her life as she embarks on her motherhood journey. Waiting for the birth of a new life can be very exciting for mothers. Positive birth is an approach that asks the woman to approach her birth story from a positive perspective and to have a stronger, more impressive and positive birth experience. Primipara pregnant women especially benefit from and need this positive birth approach. Motivational interviews are interviews conducted to support positive births and to help women develop a positive attitude towards their birth experiences.This planned study was planned as a randomized controlled trial with pre-test and post-test measurements, with the aim of determining the level of traumatic birth perception in primipara women who were given or not given training and examining the effects of positive birth motivational education by taking into account the need for education with numerical data., conditionsModule conditions: Pregnancy Related, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: In the project, it was calculated that the experimental and control groups should have at least 30 observations each, and the sample of the study was calculated as 60 pregnant women. It was aimed to interview a total of 60 pregnant women, 30 in the control group and 30 in the experimental group., primaryPurpose: PREVENTION, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: motivational discussion group, outcomesModule primaryOutcomes measure: Primipara Pregnant Women and Traumatic Birth, eligibilityModule sex: FEMALE, minimumAge: 20 Years, maximumAge: 35 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06332911, orgStudyIdInfo id: RO-231129, briefTitle: Shockwave™Peripheral Intravascular Lithotripsy Balloon for Advanced Endovascular Aortic Repair, acronym: TEVAR, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-08-01, primaryCompletionDateStruct date: 2025-08-30, completionDateStruct date: 2026-08-30, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Rede Optimus Hospitalar SA, class: NETWORK, collaborators name: Shockwave Medical, Inc., descriptionModule briefSummary: Shockwave TEVAR is a nonrandomized, prospective, international, multi-center, PMCF, obervational study.The aim of this study is to evaluate the outcomes of the Shockwave™ Peripheral Intravascular Lithotripsy Balloon (Shockwave Medical Inc.) in the routine treatment of hostile iliac accesses during TEVAR and F/BEVAR., conditionsModule conditions: Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture, conditions: Abdominal Aortic Aneurysm Without Rupture, conditions: Thoracic Aortic Aneurysm Without Rupture, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Shockwave™ Peripheral Intravascular Lithotripsy Balloon M5+, outcomesModule primaryOutcomes measure: Efficacy: Technical success - defined as intention-to-treat basis, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06332898, orgStudyIdInfo id: AG-01-0324, briefTitle: The Effects of a Nutritional Supplement on Nutrient Status and Quality of Life, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-31, primaryCompletionDateStruct date: 2024-10-31, completionDateStruct date: 2025-02-04, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-04-01, sponsorCollaboratorsModule leadSponsor name: Athletic Greens International, class: INDUSTRY, collaborators name: Citruslabs, descriptionModule briefSummary: This study is a randomized, double-blind, placebo-controlled study of N=120 apparently healthy men and women. The purpose of this study is to assess the effect of a novel dietary supplement on blood markers of nutrient status, gut microbiome, and overall quality of life., conditionsModule conditions: Nutrition, Healthy, conditions: Gastrointestinal Microbiome, conditions: Healthy Aging, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized, Double-Blind, Placebo Controlled Design, primaryPurpose: OTHER, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: AG1 - Nutritional Supplement, interventions name: Placebo, outcomesModule primaryOutcomes measure: Homocysteine, primaryOutcomes measure: Vitamin B12, primaryOutcomes measure: Folate, primaryOutcomes measure: Red Blood Cell Folate, primaryOutcomes measure: Zinc, primaryOutcomes measure: Vitamin C, primaryOutcomes measure: Gut Microbiome, secondaryOutcomes measure: Dietary habits, secondaryOutcomes measure: Gastrointestinal Health, secondaryOutcomes measure: Fatigue & energy, secondaryOutcomes measure: Well-being, secondaryOutcomes measure: Complete Metabolic Blood Panel, secondaryOutcomes measure: Complete Blood Count, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06332859, orgStudyIdInfo id: FOR-0022, briefTitle: Effectiveness of a Resilience-Based Rehabilitation Program for Patients With Coronary Heart Disease, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-15, primaryCompletionDateStruct date: 2026-10-14, completionDateStruct date: 2026-10-14, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Pensionsversicherungsanstalt, class: OTHER, descriptionModule briefSummary: To handle daily life challenges, one needs to be psychologically resilient. It plays a crucial role in disease development, prognosis, as well as social, occupational, and community participation. Cardiovascular diseases cause physical and psychological stress, which can be linked to individual resilience and the development of such diseases. Stress can trigger TakoTsubo cardiomyopathy and acute coronary events. Individuals who have experienced TakoTsubo cardiomyopathy or an acute coronary event often feel stressed due to emotional or physical triggers. These triggers may include job loss or illness. In medical rehabilitation, therapists consider the individual circumstances of their patients when planning therapy. It may be important to add a special focus on psychological care, including building resilience, which could greatly benefit these individuals. Therefore, the study aims to investigate whether resilience training, as part of an inpatient multidisciplinary rehabilitation program, affects the individual resilience of rehabilitants with TakoTsubo cardiomyopathy or those who have experienced an acute coronary event., conditionsModule conditions: Takotsubo Cardiomyopathy, conditions: Acute Coronary Syndrome, conditions: Psychological Resilience, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 130, type: ESTIMATED, armsInterventionsModule interventions name: Resilience training, outcomesModule primaryOutcomes measure: Resilience scale-13 (RS-13), primaryOutcomes measure: Brief Resilience scale - German Version (BRS), secondaryOutcomes measure: European Quality of Life 5 Dimensions 5 Level (EQ-5D-5L), secondaryOutcomes measure: Patient Health Questionnaire-4 (PHQ-4), secondaryOutcomes measure: Maximal incremental exercise test, secondaryOutcomes measure: Work ability index (WAI), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06332846, orgStudyIdInfo id: KB-0012/06/10, briefTitle: Oral Health in Patients Hospitalized Because of Ischemic Stroke, statusModule overallStatus: COMPLETED, startDateStruct date: 2019-10-10, primaryCompletionDateStruct date: 2021-11-15, completionDateStruct date: 2023-12-10, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Pomeranian Medical University Szczecin, class: OTHER, descriptionModule briefSummary: Maintaining good oral health is essential for general health and quality of life. Results of many anal-yses showed that stroke patients had poorer oral condition and worse periodontal status than control population. The aim of the study was to carry out a clinical observation concerning condition of oral health in stroke patients and healthy population.The oral health was assessed in patients with stroke and in (control group). The following elements were assessed: missing teeth, the presence of active caries foci, the presence of existing fillings and prosthetic restorations. To assess oral hygiene API (Approximal Plaque Index) was used. As part of periodontal examina-tion, the following were assessed: the presence of dental deposits, the depth of the existing periodontal pockets, tooth mobility according to Hall and Sulcus Bleeding Index during probing (SBI)., conditionsModule conditions: Oral Disease, conditions: Stroke, Ischemic, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 118, type: ACTUAL, armsInterventionsModule interventions name: oral examination, interventions name: oral examination, outcomesModule primaryOutcomes measure: Oral health status, primaryOutcomes measure: Oral hygiene assessment, primaryOutcomes measure: Periodontal status- periodontal pockets, primaryOutcomes measure: Periodontal status-tooth mobility, primaryOutcomes measure: Periodontal status- bleeding, eligibilityModule sex: ALL, minimumAge: 45 Years, maximumAge: 89 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Pomeranian Medical University in Szczecin, city: Szczecin, zip: 70-111, country: Poland, geoPoint lat: 53.42894, lon: 14.55302, hasResults: False
protocolSection identificationModule nctId: NCT06332833, orgStudyIdInfo id: 235, briefTitle: Availability of Venous Conduits in Patients With Varicose Veins for Arterial Bypass Surgery, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-12-01, primaryCompletionDateStruct date: 2024-05-31, completionDateStruct date: 2024-05-31, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Pirogov Russian National Research Medical University, class: OTHER, descriptionModule briefSummary: Patients with PAD having superficial femoral artery (SFA) occlusion were consecutively enrolled. Demographic data and medical history were taken. Physical examination and duplex ultrasound were performed., conditionsModule conditions: Varicose Veins, conditions: Peripheral Arterial Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 80, type: ESTIMATED, outcomesModule primaryOutcomes measure: availability of saphenous trunks as possible grafts, secondaryOutcomes measure: presence of varicose veins, secondaryOutcomes measure: type of previous invasive procedure, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Veronika Golovina, status: RECRUITING, city: Moscow, state: Pirogov Russian National Research Medical University, zip: 109044, country: Russian Federation, contacts name: Veronika Golovina, MD, PHD, role: CONTACT, phone: +79776051708, email: nikuskin@inbox.ru, geoPoint lat: 55.75222, lon: 37.61556, hasResults: False