hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06377215, orgStudyIdInfo id: Pro00041729, secondaryIdInfos id: R01DC020514, type: NIH, link: https://reporter.nih.gov/quickSearch/R01DC020514, briefTitle: Understanding Aided Speech Perception in Noise, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-15, primaryCompletionDateStruct date: 2028-03-01, completionDateStruct date: 2028-03-01, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: University of South Florida, class: OTHER, collaborators name: National Institute on Deafness and Other Communication Disorders (NIDCD), descriptionModule briefSummary: The overarching hypothesis to be evaluated using this protocol is that age-related hearing loss (ARHL) leads to shifts in the functional spatial boundaries between segregated and integrated auditory streams, and that hearing aid intervention that relies on directional processing schemes is most effective for those that have the poorest spatial sensitivity. One key component of the research design is to measure both behavioral and neurophysiological indices of an individual's spatial segregation boundary. The second key component is to measure the cost or benefit associated with hearing aid intervention in older hearing-impaired listeners. The final component is to relate cost and benefit of hearing aid intervention to spatial sensitivity measures that might predict the efficacy of clinical intervention., conditionsModule conditions: Hearing Impairment, Sensorineural, conditions: Spatial Perception, conditions: Aging, conditions: Hearing Aids, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 121, type: ESTIMATED, armsInterventionsModule interventions name: Open-source master hearing aid, outcomesModule primaryOutcomes measure: Digit Identification, primaryOutcomes measure: Neural Segregation, secondaryOutcomes measure: Minimum Audible Angle (MAA), secondaryOutcomes measure: Speech Localization Error, secondaryOutcomes measure: Fixed Spatial Release from Masking, otherOutcomes measure: Pure-tone Air Threshold (PTac), otherOutcomes measure: Bone Conduction Threshold (PTbc), otherOutcomes measure: Wideband Tympanometry (Equivalent Ear Canal Volume), otherOutcomes measure: Wideband Tympanometry (Static Peak Pressure), otherOutcomes measure: Wideband Tympanometry (Resonant Frequency), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: USF Research Park BPB, 3802 Spectrum Boulevard, Suite 210C, city: Tampa, state: Florida, zip: 33612, country: United States, contacts name: Erol Ozmeral, Ph.D., role: CONTACT, phone: 813-974-9778, email: eozmeral@usf.edu, contacts name: Carrie Secor, Au.D., role: CONTACT, phone: 813-974-4148, email: csecor@usf.edu, contacts name: Erol Ozmeral, Ph.D., role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 27.94752, lon: -82.45843, hasResults: False
protocolSection identificationModule nctId: NCT06377202, orgStudyIdInfo id: SynKIR-110 LTFU, briefTitle: Long-Term Follow-Up Safety Study of Subjects Treated With SynKIR-110 in Cancer Studies, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-11-15, primaryCompletionDateStruct date: 2038-12-15, completionDateStruct date: 2038-12-15, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Verismo Therapeutics, class: INDUSTRY, descriptionModule briefSummary: The primary objective of this study is to evaluate the long-term safety of SynKIR- 110 administered to adult subjects with solid tumors expressing mesothelin., conditionsModule conditions: Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, outcomesModule primaryOutcomes measure: Number of subjects with treatment related adverse events as assessed by CTCAE v5.0, secondaryOutcomes measure: Number of subjects with persistence of SynKIR-110 modified cells, secondaryOutcomes measure: Number of subjects with potential/suspected RCL, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Pennsylvania, status: RECRUITING, city: Philadelphia, state: Pennsylvania, zip: 19104, country: United States, contacts name: Katie Elkins, role: CONTACT, phone: 215-615-6740, email: katie.elkins@pennmedicine.upenn.edu, contacts name: Janos Tanyi, MD, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 39.95233, lon: -75.16379, hasResults: False
protocolSection identificationModule nctId: NCT06377176, orgStudyIdInfo id: NTUNHSEN, briefTitle: Postpartum Massage Therapy for Women and Infants: The Effect on Maternal Depression, Stress, Fatigue and Infant Temperament, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-06-16, primaryCompletionDateStruct date: 2021-10-03, completionDateStruct date: 2021-10-03, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: National Taipei University of Nursing and Health Sciences, class: OTHER, descriptionModule briefSummary: Mother and infant massage, a type of complementary therapy, possesses the capacity to ameliorate maternal depression, stress, fatigue, and also infant temperaments and convert them into more manageable ones. The objective of this study was to determine the effect of mother and infant massage therapy on maternal depression, stress, fatigue, and infant temperament. In this quasi-experimental study, a total of 102 participants were allocated into two groups based on a pretest and posttest. During a period of five weeks, the experimental groups were subjected to ten massages per week, twice every week. On the data, a generalized estimating equation (GEE) was implemented. This study's hypothesis was an improvement in maternal depression, stress, fatigue, and infant temperament., conditionsModule conditions: Postpartum Depression, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: A quasi-experimental design was utilized in this investigation; it comprised a pre-test and a post-test administered to two distinct groups. The intervention group was subjected to pre-testing before receiving the intervention, and after the intervention, mother and infant massage treatment was delivered to the intervention group. Post-testing was performed on both groups, with the control group receiving mother and infant massage., primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 102, type: ACTUAL, armsInterventionsModule interventions name: Massage therapy, outcomesModule primaryOutcomes measure: Depression, secondaryOutcomes measure: Stress, secondaryOutcomes measure: Fatigue, secondaryOutcomes measure: Infant temperament, eligibilityModule sex: ALL, minimumAge: 1 Month, maximumAge: 50 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Community Health Center, city: Sleman, state: Yogyakarta, zip: 55584, country: Indonesia, geoPoint lat: -7.71556, lon: 110.35556, hasResults: False
protocolSection identificationModule nctId: NCT06377163, orgStudyIdInfo id: acquired pneumonia in children, briefTitle: Bacterial Pathogens Associated With Community-acquired Pneumonia in Children, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-01-01, primaryCompletionDateStruct date: 2021-08-31, completionDateStruct date: 2021-08-31, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Delta University for Science and Technology, class: OTHER, descriptionModule briefSummary: Pediatric community acquired pneumonia (CAP) is one of the most common reasons for hospital admission, there is no reliable way of distinguishing the causative organism based on clinical features.This study examined common pathogens of community-acquired pneumonia from 28 days up to 10 years in Dakahlia Governorate., conditionsModule conditions: Children Pneumonia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 100, type: ACTUAL, outcomesModule primaryOutcomes measure: Complete blood count, primaryOutcomes measure: C-reactive protein (CRP), primaryOutcomes measure: Blood culture and sensitivity on admission, primaryOutcomes measure: Gastric lavage culture or sputum culture on admission, eligibilityModule sex: ALL, minimumAge: 28 Days, maximumAge: 10 Years, stdAges: CHILD, contactsLocationsModule locations facility: Amira Hussin Mohammed, city: Gamasa, zip: 35712, country: Egypt, geoPoint lat: 31.44112, lon: 31.53675, hasResults: False
protocolSection identificationModule nctId: NCT06377150, orgStudyIdInfo id: ABCA4-1382022BO2, briefTitle: Stargardt Disease in Childhood, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-04-01, primaryCompletionDateStruct date: 2024-03-31, completionDateStruct date: 2024-03-31, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: University Hospital Tuebingen, class: OTHER, descriptionModule briefSummary: Retrospective chart review study to elucidate the phenotype and genotype of children with ABCA4-associated Stargardt disease., conditionsModule conditions: Stargardt Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 39, type: ACTUAL, outcomesModule primaryOutcomes measure: Best Corrected Visual Acuity (BCVA), primaryOutcomes measure: Visual Field (VF), primaryOutcomes measure: Fundus Photography (FP), primaryOutcomes measure: Fundus Autofluorescence (AF), primaryOutcomes measure: Optical Coherence Tomography (OCT), primaryOutcomes measure: Full-Field Electroretinography (ff-ERG), eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University Hospital Tuebingen, city: Tuebingen, state: Baden-Wuerttemberg, Germany, zip: 72076, country: Germany, geoPoint lat: 48.52266, lon: 9.05222, hasResults: False
protocolSection identificationModule nctId: NCT06377059, orgStudyIdInfo id: 2024-RH-phase1-WARD, briefTitle: Early Detection of Complications During Immunotherapy for Haematological Malignancy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-07-01, primaryCompletionDateStruct date: 2026-07-01, completionDateStruct date: 2027-07-01, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Rigshospitalet, Denmark, class: OTHER, descriptionModule briefSummary: Aims* To identify patients that should remain admitted in hospital for more intense surveillance because of high risk for development of clinical complications* Expand the understanding of the interactions between physiology and immunology for the design of future projects and general knowledge Hypothesis Development of a risk model based on a combination of physiological and immunological parameters can contribute to early detection of patients at risk for clinical complications after anti-cancer treatment., conditionsModule conditions: Hematologic Cancer, conditions: CRS - Cytokine Release Syndrome, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: WARD, outcomesModule primaryOutcomes measure: CRS, secondaryOutcomes measure: Immune response, secondaryOutcomes measure: severe physiological deviations, secondaryOutcomes measure: clinical complications, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06377007, orgStudyIdInfo id: WU66290, secondaryIdInfos id: WU66290, type: OTHER_GRANT, domain: Walailak individual grant, briefTitle: Refractive Outcomes and Ocular Biometry of Two Swept-Source Optical Coherence Tomography-Based Biometers With Segmental or Equivalent Refractive Indices (ORION), acronym: ORION, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-01, primaryCompletionDateStruct date: 2025-07-30, completionDateStruct date: 2025-12-30, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-26, sponsorCollaboratorsModule leadSponsor name: Walailak University, class: OTHER, descriptionModule briefSummary: Cataract surgery represents a common surgical intervention, encompassing the extraction of the opaque natural crystalline lens, followed by the substitution with an artificial intraocular lens (IOL). To ascertain an IOL possessing optimal power, antecedent to the surgery, preoperative evaluations are conducted through the utilization of a biometric devices. Diverse categories of these instruments are accessible, each harnessing distinct optical methodologies or mathematical algorithms to ascertain the most fitting IOL power. The principal objective of this study was to evaluate the ocular biometry and the predictive precision outcome of a biometer that uses standard keratometry to the prediction accuracy of another biometer that uses Total Keratometry., conditionsModule conditions: Cataract, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, enrollmentInfo count: 142, type: ESTIMATED, armsInterventionsModule interventions name: IOLMaster 700 (Carl Zeiss Meditec AG), interventions name: Argos (Alcon Laboratories, Inc.), outcomesModule primaryOutcomes measure: Mean absolute prediction error, secondaryOutcomes measure: Proportion of eyes with an absolute prediction error equal to or less than 0.25, eligibilityModule sex: ALL, minimumAge: 50 Years, maximumAge: 85 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Walailak University, status: RECRUITING, city: Nakhon Si Thammarat, zip: 80160, country: Thailand, contacts name: Jakkrit.ju Juhong, MD., role: CONTACT, phone: 0816773406, email: jakkrit.ju@wu.ac.th, geoPoint lat: 8.43333, lon: 99.96667, hasResults: False
protocolSection identificationModule nctId: NCT06376994, orgStudyIdInfo id: IRB00407311, secondaryIdInfos id: 1U24HL169566-01, type: NIH, link: https://reporter.nih.gov/quickSearch/1U24HL169566-01, briefTitle: Multi-Center Clean Air Randomized Controlled Trial in COPD, acronym: Clean Air, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09, primaryCompletionDateStruct date: 2027-09, completionDateStruct date: 2028-09, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: JHSPH Center for Clinical Trials, class: OTHER, collaborators name: National Heart, Lung, and Blood Institute (NHLBI), descriptionModule briefSummary: This is a multi-center randomized, sham-controlled clinical trial to determine the effectiveness of an air cleaner intervention aimed at improving indoor air quality on reducing COPD exacerbation risk and improving quality of life, functional status, rescue medication use., conditionsModule conditions: Chronic Obstructive Pulmonary Disease (COPD), designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 770, type: ESTIMATED, armsInterventionsModule interventions name: Air cleaner, interventions name: Sham air cleaner, outcomesModule primaryOutcomes measure: St. George's Respiratory Questionnaire (SGRQ), eligibilityModule sex: ALL, minimumAge: 40 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Johns Hopkins, city: Baltimore, state: Maryland, zip: 21224, country: United States, contacts name: Wendy Lorizio, role: CONTACT, phone: 410-510-2449, email: wlorizi1@jhmi.edu, contacts name: Maggie Maly, role: CONTACT, phone: 410-550-9527, email: mmaly1@jhmi.edu, geoPoint lat: 39.29038, lon: -76.61219, hasResults: False
protocolSection identificationModule nctId: NCT06376981, orgStudyIdInfo id: CHD23_0025, briefTitle: Hyaluronic Acid in Shoulder Tendinopathy, acronym: ACCTE, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2026-08, completionDateStruct date: 2026-11, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Centre Hospitalier Departemental Vendee, class: OTHER, descriptionModule briefSummary: Multicentric, randomised study to compare the effectiveness on activity pain at 3 months of corticosteroid injection associated with hyaluronic acid with corticosteroids injection alone in patients with tendinopathy of the supraspinatus with clinical reevaluation at one, three and six months., conditionsModule conditions: Shoulder Tendinitis, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 132, type: ESTIMATED, armsInterventionsModule interventions name: Hyaluronic acid injection, interventions name: Corticosteroid injection, interventions name: Placebo injection, outcomesModule primaryOutcomes measure: Visual analog scale pain on activity ranging from 0 to 100 mm at month 3., eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: CHD Vendée, city: La Roche-sur-Yon, country: France, contacts name: Céline COZIC, Dr, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 46.66667, lon: -1.43333, locations facility: CHU Nantes, city: Nantes, country: France, contacts name: Christelle DARRIEUTORT-LAFFITE, Dr, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 47.21725, lon: -1.55336, hasResults: False
protocolSection identificationModule nctId: NCT06376968, orgStudyIdInfo id: BA-G-H-1604, briefTitle: Prospective, Multicentre, Randomized, Controlled, Cross-over Study on the Safety and Performance of the Biologic Fusion Option of DialogiQ Compared to Haemodialysis Without Biologic Fusion in Hypotension Prone Patients on Maintenance Haemodialysis, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-22, primaryCompletionDateStruct date: 2025-07, completionDateStruct date: 2025-08, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: B.Braun Avitum AG, class: INDUSTRY, descriptionModule briefSummary: The goal of this prospective, randomized, controlled, cross-over, multicentric study is to demonstrate the safety of bioLogic Fusion in patients on chronic haemodialysis or hemodiafiltration prone to hypotensive episodes. The main question it aims to answer is:• Which is the number and percentage of individual sessions with reached prescribed post-dialysis body weight in the prescribed treatment time in each single session in hypotensive-prone patients on high-flux haemodialysis or hemodiafiltration within each patient with treatments performed with DialogiQ with (treatment A) or without (treatment B) the bioLogic Fusion option activated? Participants will in addition to their routine dialysis treatment undergo 2 physical examinations and regularly answer questionnaires.A crossover design is used to compare treatments with or without the BioLogic Fusion function activated., conditionsModule conditions: Renal Dialysis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 56, type: ESTIMATED, armsInterventionsModule interventions name: BioLogic Fusion, outcomesModule primaryOutcomes measure: Post-dialysis body weight, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Policlinico S. Orsola - Malpighi - UOC Nefrologia, Dialisi e Ipertensione, status: RECRUITING, city: Bologna, state: Emilia Romagna, zip: 40138, country: Italy, contacts name: Annalisa Zucchelli, Prof., role: CONTACT, contacts name: Annalisa Zucchelli, Prof., role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 44.49381, lon: 11.33875, hasResults: False
protocolSection identificationModule nctId: NCT06376955, orgStudyIdInfo id: IRB00014233-1, briefTitle: High Intensity Interval Versus Focused Ultrasound on Insulin Resistance in Diabetics With Abdominal Obesity, acronym: diabetic, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-16, primaryCompletionDateStruct date: 2024-08-30, completionDateStruct date: 2024-08-30, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Badr University, class: OTHER, descriptionModule briefSummary: Obesity and diabetes share a common insulin resistance pathway and contribute to chronic hyperglycemia. Both high-intensity interval exercise (HIIE) and focused ultrasound (FUS) have been explored in the context of managing insulin resistance in diabetic individuals with abdominal obesity, though they operate through different mechanisms and have different implications., conditionsModule conditions: Insulin Resistance, conditions: Abdominal Obesity, conditions: Diabetes, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: High intensity interval exercise, interventions name: Focused ultrasound, outcomesModule primaryOutcomes measure: Body mass index, primaryOutcomes measure: Waist circumference, primaryOutcomes measure: Skin fold, primaryOutcomes measure: Value of HbA1c and HOMA-IR hormone, eligibilityModule sex: FEMALE, minimumAge: 25 Years, maximumAge: 35 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False