protocolSection identificationModule nctId: NCT06360003, orgStudyIdInfo id: SAHoWMU-CR2024-01-109, briefTitle: "Right Ventricular Outflow Tract Posterior Septum Pacing" in Predicting Ventricular Outflow Tract Ventricular Tachycardia Origin, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-04-01, primaryCompletionDateStruct date: 2025-04-01, completionDateStruct date: 2025-08-01, studyFirstPostDateStruct date: 2024-04-11, lastUpdatePostDateStruct date: 2024-04-11, sponsorCollaboratorsModule leadSponsor name: Second Affiliated Hospital of Wenzhou Medical University, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to make clear that a new method, right ventricular outflow tract (RVOT) posterior septum pacing, has a greater accuracy in predicting the origin of ventricular outflow tract (VOT) ventricular arrhythmias (VAs) compared to the previous electrocardiographic standards for the identification of the origin of ventricular outflow tract. The secondary aim is to investigate, by using the new method, if it can optimize the procedure of radiofrequency catheter ablation.Researches will break the method of this investigation into two steps:First step have enrolled 100 patients. This step would be used to compare the results predicted by right ventricular outflow tract posterior septum pacing, with the previously used electrocardiographic criteria and actual target site.The second step will enroll another 100 patients. In this step, patients will be divided into two groups, one being the new protocol group and the other being the convention group. Patients will also be followed up, for 1 month and 3 months at outpatient clinic post procedure. Procedure time, success rate, fluoroscopy exposure time and complications, are compared between RVOT posterior septum pacing group and convention group., conditionsModule conditions: Ventricular Outflow Tract Ventricular Arrhythmias, conditions: Radio Frequency Catheter Ablation, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Right Ventricular Outflow Tract Posterior Septum Pacing, interventions name: systemic mapping and ablation, outcomesModule primaryOutcomes measure: Rate of Immediate Ablation Success, primaryOutcomes measure: Rate of Ablation Complication, primaryOutcomes measure: Accuracy of RVOT posterior septal pacing protocol, secondaryOutcomes measure: Incidence of Complications Post-operative, secondaryOutcomes measure: Incidence of Complication, secondaryOutcomes measure: Rate of Recurrence during Follow up, secondaryOutcomes measure: Incidence of Complication, secondaryOutcomes measure: Rate of Recurrence during Follow up, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 90 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, status: RECRUITING, city: Wenzhou, state: Zhejiang, zip: 325000, country: China, contacts name: Cheng Zheng, PhD, role: CONTACT, phone: 86-0577-85676609, email: zhengcheng_wzmufey@163.com, geoPoint lat: 27.99942, lon: 120.66682, hasResults: False