protocolSection identificationModule nctId: NCT06371781, orgStudyIdInfo id: Cumhuriyetobgyn, secondaryIdInfos id: 1919B012108892, type: OTHER_GRANT, domain: TUBITAK, briefTitle: Examination of the Relationship Between Weight Gain During Pregnancy and Sfrp-5, Netrin-4 and Resistin Concentrations, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-07-01, primaryCompletionDateStruct date: 2022-07-01, completionDateStruct date: 2023-07-01, studyFirstPostDateStruct date: 2024-04-17, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Cumhuriyet University, class: OTHER, collaborators name: Scientific and Technological Research Council of Turkey (TUBITAK), descriptionModule briefSummary: Researchers thought that the molecules Sfrp-5, Resistin and Netrin-4, which will be examine, they may have a significant effect on weight gain during pregnancy. Based on these foundations, researchers expect changes in the levels of these molecules in women who gain excessive weight during pregnancy. In this study, researchers aimed to examine the moderator relationship between the molecules will be examine and weight gain in women who gained weight above the normal limits determined during pregnancy. For this reason, 44 participant who gained excessive weight during pregnancy and 46 pregnant participant who gained normal weight were included in the study. The levels of Netrin-4, Sfrp-5 and Resistin molecules in the blood serum of the individuals in the study group were measured with a Commercial Elisa kit., conditionsModule conditions: Excessive Weight Gain During Pregnancy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Pregnant women who were given birth at Cumhuriyet University Faculty of Medicine Hospital Gynecology and Obstetrics Clinic between July 1, 2021 and July 1, 2022 and whose pregnancy follow-ups were performed in our hospital will be included in our prospectively designed study. Researchers will divide the study into two main groups. The first group will consist of pregnant women with above-normal weight gain during pregnancy, and the other group will consist of pregnant women with normal weight gain during pregnancy. It is estimated that 46 control and 44 pregnant women with overweight will be reached during this period. In the study, first a form containing demographic data such as age, education, height and weight will be filled out., primaryPurpose: SCREENING, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 90, type: ACTUAL, armsInterventionsModule interventions name: Serum Netrin-4, Resistin and Sfrp-5 level measurement, outcomesModule primaryOutcomes measure: Obtaining blood serum for measurement of serum Sfrp-5, Netrin-4 and Resistin, secondaryOutcomes measure: Calculating BMI (kg/m^2) from height (m) and weight (kg) measurement values for diagnosis., eligibilityModule sex: FEMALE, minimumAge: 20 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Sivas Cumhuriyet University, city: Sivas, state: Centre, zip: 58140, country: Turkey, geoPoint lat: 39.74833, lon: 37.01611, hasResults: False