protocolSection identificationModule nctId: NCT06305624, orgStudyIdInfo id: 2024-0130, secondaryIdInfos id: 1R01DA047279-01, type: NIH, link: https://reporter.nih.gov/quickSearch/1R01DA047279-01, secondaryIdInfos id: A532000, type: OTHER, domain: UW Madison, secondaryIdInfos id: Protocol Version 2/21/2024, type: OTHER, domain: UW Madison, briefTitle: Implementation of Mobile-based Programs for Alcohol Cessation in Treatment of Alcohol-associated Liver Disease, acronym: IMPACT-ALD, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2027-10, completionDateStruct date: 2027-10, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: University of Wisconsin, Madison, class: OTHER, collaborators name: National Institute on Drug Abuse (NIDA), descriptionModule briefSummary: This protocol describes a randomized controlled trial testing the effectiveness and implementability of the CHESS Health Connections smartphone application among patients with alcohol-associated liver disease (ALD) at two medical centers in Michigan and Wisconsin, in two types of clinics: general hepatology and multidisciplinary that offers care for advanced ALD alongside co-located, integrated mental health and substance abuse treatment. The long-term goal of this and future work is to prevent disease progression and promote healthy behaviors by improving the rate of abstinence among patients with ALD earlier in the course of their disease. 298 participants will be enrolled and can expect to be on study for up to 6 months., conditionsModule conditions: Alcohol Use Disorder, conditions: Alcohol-related Liver Disease, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized, controlled, Type 1 hybrid implementation-effectiveness trial., primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 298, type: ESTIMATED, armsInterventionsModule interventions name: Connections App, outcomesModule primaryOutcomes measure: Days of Alcohol Abstinence in ALD Participants, primaryOutcomes measure: Number of Standard Drinks Consumed in ALD Participants, secondaryOutcomes measure: Change in Patient Health Questionnaire (PHQ-8) Score, secondaryOutcomes measure: Change in PROMIS Global Health Score, secondaryOutcomes measure: Change in Generalized Anxiety Disorder (GAD-7) Score, secondaryOutcomes measure: Change in Insomnia Severity Index (ISI) Score, secondaryOutcomes measure: Change in Pain Interference (PEG) Score, secondaryOutcomes measure: Change in Drinking Motivations Questionnaire - Adult (DMQ-A) Score, secondaryOutcomes measure: Change in CHESS Bonding Scale Score, secondaryOutcomes measure: Change in Drug-Taking Confidence Questionnaire (DTCQ-8A) Score, secondaryOutcomes measure: Change in Treatment Self-Regulation Questionnaire (TSRQ) Score, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: UM General Hepatology Clinic, city: Ann Arbor, state: Michigan, zip: 48109, country: United States, geoPoint lat: 42.27756, lon: -83.74088, locations facility: UM Multidisciplinary ALD Clinic, city: Ann Arbor, state: Michigan, zip: 48109, country: United States, geoPoint lat: 42.27756, lon: -83.74088, locations facility: UW General Hepatology Clinic, city: Madison, state: Wisconsin, zip: 53705, country: United States, geoPoint lat: 43.07305, lon: -89.40123, locations facility: UW Multidisciplinary ALD Clinic, city: Madison, state: Wisconsin, zip: 53705, country: United States, geoPoint lat: 43.07305, lon: -89.40123, hasResults: False