hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06305637, orgStudyIdInfo id: KTCS-2302, briefTitle: A Study Comparing Ketoconazole Shampoo, 2% and Ketoconazole 2% Shampoo (RS) in the Treatment of Tinea Versicolor., statusModule overallStatus: COMPLETED, startDateStruct date: 2023-12-04, primaryCompletionDateStruct date: 2024-02-10, completionDateStruct date: 2024-02-10, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Taro Pharmaceuticals USA, class: INDUSTRY, descriptionModule briefSummary: To demonstrate the efficacy, therapeutic equivalence and safety of Ketoconazole Shampoo, 2% (Taro Pharmaceuticals U.S.A., Inc.) and Ketoconazole 2% Shampoo (Reference Standard) in the treatment of tinea versicolor., conditionsModule conditions: Tinea Versicolor, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, enrollmentInfo count: 430, type: ACTUAL, armsInterventionsModule interventions name: Ketoconazole Shampoo, 2%, interventions name: Ketoconazole Shampoo, 2% (Reference Standard), interventions name: Placebo, outcomesModule primaryOutcomes measure: To demonstrate the therapeutic equivalence and safety of the Investigational Product, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Taro, city: Hawthorne, state: New York, zip: 10532, country: United States, geoPoint lat: 41.10732, lon: -73.79597, hasResults: False
protocolSection identificationModule nctId: NCT06305598, orgStudyIdInfo id: I-3298823, secondaryIdInfos id: NCI-2024-01390, type: REGISTRY, domain: CTRP (Clinical Trial Reporting Program), secondaryIdInfos id: I-3298823, type: OTHER, domain: Roswell Park Cancer Institute, briefTitle: Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2026-04-01, completionDateStruct date: 2027-04-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-04-25, sponsorCollaboratorsModule leadSponsor name: Roswell Park Cancer Institute, class: OTHER, descriptionModule briefSummary: This phase I trial tests the change in androgen receptor sensitivity, side effects and effectiveness of bipolar androgen therapy, using testosterone, in patients with castration resistant prostate cancer that has spread to other places is the body (metastatic). Bipolar androgen therapy is the regulation of testosterone between castration levels (lower than what would be normally present) and supraphysiological levels (amounts greater than normally found in the body). This may suppress cancer cell growth, which reduces prostate-specific antigen (PSA) levels and may delay cancer progression., conditionsModule conditions: Castration-Resistant Prostate Carcinoma, conditions: Metastatic Prostate Carcinoma, conditions: Stage IVB Prostate Cancer AJCC v8, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 14, type: ESTIMATED, armsInterventionsModule interventions name: Biopsy, interventions name: Bone Scan, interventions name: Computed Tomography, interventions name: Leuprolide Acetate, interventions name: Magnetic Resonance Imaging, interventions name: Survey Administration, interventions name: Testosterone Cypionate, outcomesModule primaryOutcomes measure: Androgen receptor (AR) activity, secondaryOutcomes measure: Incidence of adverse events, secondaryOutcomes measure: Incidence of serious adverse events, secondaryOutcomes measure: Prostate specific antigen (PSA) 50, secondaryOutcomes measure: Measurable disease response, secondaryOutcomes measure: Progression free survival, secondaryOutcomes measure: Overall survival, secondaryOutcomes measure: Assess Quality of life, secondaryOutcomes measure: Assess Quality of Life, secondaryOutcomes measure: Assess Fatigue, secondaryOutcomes measure: Assess change in Fatigue, eligibilityModule sex: MALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Roswell Park Cancer Institute, status: RECRUITING, city: Buffalo, state: New York, zip: 14263, country: United States, contacts name: Gurkamal S. Chatta, role: CONTACT, phone: 716-845-3117, email: Gurkamal.Chatta@RoswellPark.org, contacts name: Gurkamal S. Chatta, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 42.88645, lon: -78.87837, hasResults: False
protocolSection identificationModule nctId: NCT06305585, orgStudyIdInfo id: IRB# 23-214, briefTitle: Can a Novel Manual Therapy Technique Help Relieve Stress? Assessing Effects of Primal Reflex Release on the Body's Stress Response, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2025-03, completionDateStruct date: 2025-03, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: University of Idaho, class: OTHER, collaborators name: CJ Brush, collaborators name: Jayme Baker, collaborators name: Sydney Leverett, descriptionModule briefSummary: Stress, when left unmanaged, can have detrimental effects on both physical and mental health, contributing to conditions such as high blood pressure, anxiety, and even cardiovascular disease. Effective stress management therapies may help maintain overall well-being and reduce the risk of long-term health complications. The Primal Reflex Release Technique (PRRT) is a novel manual therapy that may reduce markers related to stress such as heart rate variability (HRV) and patient-reported outcomes (PROs). Therefore, the purpose of this study is to elucidate the potential for PRRT to improve HRV and PROs., conditionsModule conditions: Psychological Stress, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Primal Reflex Release Technique (PRRT), outcomesModule primaryOutcomes measure: ECG Data, primaryOutcomes measure: ICG Data, primaryOutcomes measure: Depression Anxiety Stress Scale-21 (DASS-21) - Depression, primaryOutcomes measure: Depression Anxiety Stress Scale-21 (DASS-21) - Anxiety, primaryOutcomes measure: Depression Anxiety Stress Scale-21 (DASS-21) - Stress, primaryOutcomes measure: Simple Physical Activity Questionnaire (SIMPAQ), primaryOutcomes measure: Self Assessment Manikin (SAM) - Valence, primaryOutcomes measure: Self Assessment Manikin (SAM) - Arousal, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 64 Years, stdAges: ADULT, contactsLocationsModule locations facility: ISMaRT Clinic, city: Moscow, state: Idaho, zip: 83843, country: United States, contacts name: Jayme Baker, DPT, role: CONTACT, phone: 208-885-1055, email: jaymeb@uidaho.edu, geoPoint lat: 46.73239, lon: -117.00017, hasResults: False
protocolSection identificationModule nctId: NCT06305572, orgStudyIdInfo id: H-1903-013-1014, briefTitle: Diagnostic Accuracy of Quantitative Flow Ratio, statusModule overallStatus: COMPLETED, startDateStruct date: 2019-07-30, primaryCompletionDateStruct date: 2023-03-25, completionDateStruct date: 2023-09-26, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Seoul National University Hospital, class: OTHER, collaborators name: Inje University Ilsan Paik Hospital, collaborators name: Keimyung University Dongsan Medical Center, collaborators name: Ulsan Medical Center, collaborators name: Bucheon Sejong Hospital, collaborators name: Chosun University Hospital, collaborators name: Severance Hospital, collaborators name: Ulsan University Hospital, collaborators name: Uijeongbu Eulji Medical Center, descriptionModule briefSummary: The aim of this study was to investigate the accuracy of quantitative flow ratio (QFR) for predicting fractional flow reserve (FFR) ≤0.80 in an independent core laboratory., conditionsModule conditions: Coronary Artery Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 280, type: ACTUAL, armsInterventionsModule interventions name: QFR, outcomesModule primaryOutcomes measure: Diagnostic accuracy of QFR, secondaryOutcomes measure: Sensitivity of QFR, secondaryOutcomes measure: Specificity of QFR, secondaryOutcomes measure: Correlation, eligibilityModule sex: ALL, minimumAge: 19 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Seoul National University Hospital, city: Seoul, zip: 03080, country: Korea, Republic of, geoPoint lat: 37.566, lon: 126.9784, hasResults: False
protocolSection identificationModule nctId: NCT06305546, orgStudyIdInfo id: 2911, briefTitle: Comparisons Of Different Antiplaque Agents On Gingivitis In Orthodontic Patients, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-04-01, primaryCompletionDateStruct date: 2023-10-31, completionDateStruct date: 2023-10-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-13, sponsorCollaboratorsModule leadSponsor name: Anam Sattar, class: OTHER, descriptionModule briefSummary: Fixed orthodontic treatment affects the periodontium by allowing plaque accumulation on teeth if the oral ecosystem is unfavorable which initially causes gingivitis to progress into periodontitis, and later enamel demineralization occurs. Yáñez-Vico et al observed that regular modifications per checkups were painful and unpleasant for the patient thus the patients undergoing fixed orthodontic treatments compromised their oral hygiene. This creates plaque retention sites which can lead to developing white spot lesions, caries, and periodontitis, conditionsModule conditions: Gingivitis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: TRIPLE, maskingDescription: The trial was a double blinded (patients and investigators). We were helped from a member of our department who is not a part of the study, to transfer the gels from commercial tubes to blank containers. The randomization codes remained unknown until data analysis was completed. Randomization was done by computer-generated software., whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, enrollmentInfo count: 80, type: ACTUAL, armsInterventionsModule interventions name: Chlorhexidine Gluconate, interventions name: Metronidazole, interventions name: combination gel (chlorhexidine and metronidazole), interventions name: Placebo, outcomesModule primaryOutcomes measure: gingival index, primaryOutcomes measure: bleeding index, primaryOutcomes measure: orthodontic plaque index, eligibilityModule sex: ALL, minimumAge: 16 Years, maximumAge: 35 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Dow University of Health Sciences, city: Karachi, state: Sindh, country: Pakistan, geoPoint lat: 24.8608, lon: 67.0104, hasResults: False
protocolSection identificationModule nctId: NCT06305507, orgStudyIdInfo id: 30923-N, briefTitle: Differents Laser Applications on Plantar Fasciitis, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2024-06, completionDateStruct date: 2024-07, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-13, sponsorCollaboratorsModule leadSponsor name: University of Seville, class: OTHER, descriptionModule briefSummary: The objective of this randomized controlled clinical trial (RCT) with a double-blind technique and longitudinal chronology, entitled \&#34;Effect of different laser applications on Plantar Fasciitis\&#34;, is to evaluate and compare the effectiveness of laser therapy low-level (LLLT) in local spot mode versus sweep mode in the reduction of pain associated with plantar fasciitis.The main questions it seeks to answer are:* What is the comparative effectiveness between low-level laser therapy in local spot mode and sweep mode in reducing pain in patients with plantar fasciitis?* What are the optimal therapeutic parameters (session duration, frequency and power) for LLLT in both modes, maximizing pain reduction in patients with plantar fasciitis?Participants in this study will perform the following tasks:* Undergo low-level laser therapy sessions in local spot mode or sweep mode.* Comply with the instructions on the duration and frequency of the sessions.* Record the pain levels experienced before and after each session.The investigators will compare the group undergoing local spot mode low-level laser therapy with the group undergoing sweeping mode low-level laser therapy to evaluate whether there are significant differences in pain reduction effects., conditionsModule conditions: Fasciitis, Plantar, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 62, type: ESTIMATED, armsInterventionsModule interventions name: Focussed laser therapy, interventions name: Shower laser therapy, outcomesModule primaryOutcomes measure: Pain Reduction in Patients with Plantar Fasciitis Treated with Laser Therapy (LLLT): Comparison between Local Spot Mode and Sweep Mode", secondaryOutcomes measure: Fascia thickness, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Área Clínica de Podología, city: Sevilla, state: Andalucía, zip: 41004, country: Spain, geoPoint lat: 37.38283, lon: -5.97317, locations facility: Facultad de Podologia, city: Sevilla, zip: 41009, country: Spain, contacts name: Aurora Castro, Prof titular, role: CONTACT, phone: 954486500, geoPoint lat: 37.38283, lon: -5.97317, hasResults: False
protocolSection identificationModule nctId: NCT06305494, orgStudyIdInfo id: HE671008, briefTitle: Genitourinary Syndrome of Menopause in Thai Gynecologic Cancer Survivors, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-14, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-04-25, sponsorCollaboratorsModule leadSponsor name: Khon Kaen University, class: OTHER, descriptionModule briefSummary: Women often face common cancers like ovarian, uterine, and cervical cancers. Improvements in cancer detection and treatment mean more women survive. However, survivors can encounter challenges like ongoing pain, treatment complications, and fertility issues.Treating these cancers often involves surgeries that might include removing ovaries or using pelvic radiation. This can trigger menopause in younger women, causing problems like vaginal dryness, itching, and urinary issues.Women who've gone through menopause often deal with these symptoms, affecting their daily lives, confidence, and intimate relationships. Though treatments are available, lack of awareness, embarrassment, and not discussing these issues with doctors can make managing them difficult.The main treatment for these symptoms is using vaginal estrogen, but it might not be suitable for some cancer survivors. Non-hormonal options like lubricants and moisturizers are alternatives. This study in Thailand aiming to explore how common these issues are among gynecological cancer survivors, their feelings about it, and how it affects their quality of life., conditionsModule conditions: Atrophic Vaginitis, conditions: Gynecologic Cancer, conditions: Lower Urinary Tract Symptoms, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 425, type: ESTIMATED, outcomesModule primaryOutcomes measure: Prevalence of genitourinary syndrome of menopause, secondaryOutcomes measure: Severity of genitourinary syndrome of menopause, secondaryOutcomes measure: Quality of life of gynecologic cancer survivor, secondaryOutcomes measure: Attitude toward genitourinary syndrome of menopause in gynecologic cancer survivor, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Faculty of Medicine, Khon Kaen University, status: RECRUITING, city: Khon Kaen, zip: 40002, country: Thailand, contacts name: Apiwat Jongjakapun, MD, role: CONTACT, email: apiwjo@kku.ac.th, geoPoint lat: 16.44671, lon: 102.833, hasResults: False
protocolSection identificationModule nctId: NCT06305481, orgStudyIdInfo id: OPT1099, briefTitle: Glaucoma Evaluation With the P200TE, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-13, primaryCompletionDateStruct date: 2024-09-30, completionDateStruct date: 2024-09-30, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Optos, PLC, class: INDUSTRY, descriptionModule briefSummary: Images captured on the P200TE device on glaucoma patients, conditionsModule conditions: Glaucoma, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 75, type: ESTIMATED, armsInterventionsModule interventions name: P200TE, outcomesModule primaryOutcomes measure: Number of images collected, eligibilityModule sex: ALL, minimumAge: 22 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Werner Optometry, status: RECRUITING, city: Cajon, state: California, zip: 92019, country: United States, contacts name: Kristen Mendenhall, role: CONTACT, phone: 619-937-1056, email: kristen@wernerod.com, geoPoint lat: 34.29889, lon: -117.45644, locations facility: Specialty Eyecare Centre, status: RECRUITING, city: Bellevue, state: Washington, zip: 98004, country: United States, contacts name: Renee Cook, role: CONTACT, phone: 425-454-3937, email: rcook@specialtyeyecarecentre.com, geoPoint lat: 47.61038, lon: -122.20068, hasResults: False
protocolSection identificationModule nctId: NCT06305468, orgStudyIdInfo id: APHP240055, briefTitle: Prognosis of Disseminated and Cerebral Toxoplasmosis Hospitalized in Intensive Care in the Era of PCR Diagnosis, acronym: TOXIC, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2026-04-01, completionDateStruct date: 2026-04-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Assistance Publique - Hôpitaux de Paris, class: OTHER, descriptionModule briefSummary: Toxoplasmosis is a common infection whose clinical severity can sometimes justify admission to intensive care, especially in immunocompromised patients.This study should make it possible to evaluate the impact of different anti-infective treatment regimens and to highlight clinical-biological and prognostic differences depending on the type of underlying immunosuppression., conditionsModule conditions: Toxoplasmosis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: RETROSPECTIVE, enrollmentInfo count: 200, type: ESTIMATED, outcomesModule primaryOutcomes measure: Mortality rate in intensive care., secondaryOutcomes measure: Hospital mortality rate, secondaryOutcomes measure: Length of stay in intensive care, secondaryOutcomes measure: Duration of mechanical ventilation, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 100 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Cochin hospital, city: Paris, zip: 75014, country: France, geoPoint lat: 48.85341, lon: 2.3488, hasResults: False
protocolSection identificationModule nctId: NCT06305455, orgStudyIdInfo id: HSD135, briefTitle: Resistance Profile of Escherichia Coli in Infections of Community Origin: The Importance of Antimicrobial Stewardship, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2024-07, completionDateStruct date: 2024-10, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: José Raimundo Araujo de Azevedo, class: OTHER, descriptionModule briefSummary: The main objective of the study is to describe the antimicrobial resistance profile of E. coli isolated in patients from the community - defined as those with cultures collected within 48 hours of hospital admission - and admitted to the intensive care unit., conditionsModule conditions: Antimicrobial Resistance, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: Escherichia coli ESBL, outcomesModule primaryOutcomes measure: Prevalence of Escherichia coli resistance, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False