hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06347744, orgStudyIdInfo id: RADX-P-2401, briefTitle: Radicle Rest 24: A Study of Health and Wellness Products on Sleep and Related Health Outcomes, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06, primaryCompletionDateStruct date: 2024-09, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-08, sponsorCollaboratorsModule leadSponsor name: Radicle Science, class: INDUSTRY, descriptionModule briefSummary: A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on sleep and related health outcomes., conditionsModule conditions: Sleep, conditions: Sleep Disturbance, conditions: Sleep Disorder, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Participants will be stratified based on gender at birth then randomized to one of the study arms., primaryPurpose: OTHER, maskingInfo masking: DOUBLE, maskingDescription: Participants will be stratified based on gender at birth then randomized to one of the study arms, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 1200, type: ESTIMATED, armsInterventionsModule interventions name: Radicle Rest Placebo Control Form 1, interventions name: Radicle Rest Active Study Product 1.1 Usage, interventions name: Radicle Rest Placebo Control Form 2, interventions name: Radicle Rest Active Study Product 2.1 Usage, outcomesModule primaryOutcomes measure: Change in sleep, secondaryOutcomes measure: Change in feelings of anxiety, secondaryOutcomes measure: Change in fatigue, secondaryOutcomes measure: Change in mood (emotional distress-depression), secondaryOutcomes measure: Minimal clinically important difference (MCID) in sleep, secondaryOutcomes measure: Minimal clinically important difference (MCID) in feelings of anxiety, secondaryOutcomes measure: Minimal clinically important difference (MCID) in fatigue, secondaryOutcomes measure: Minimal clinically important difference (MCID) in mood (emotional distress-depression), eligibilityModule sex: ALL, minimumAge: 21 Years, maximumAge: 105 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Radicle Science, Inc, city: Del Mar, state: California, zip: 92014, country: United States, geoPoint lat: 32.95949, lon: -117.26531, hasResults: False
protocolSection identificationModule nctId: NCT06347731, orgStudyIdInfo id: VAR-2024-01, briefTitle: Varian ProBeam360° Proton Therapy System China Clinical Trial (Wuhan), statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-07, primaryCompletionDateStruct date: 2025-03, completionDateStruct date: 2025-03, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-17, sponsorCollaboratorsModule leadSponsor name: Varian, a Siemens Healthineers Company, class: INDUSTRY, descriptionModule briefSummary: This study is a clinical trial of prospective, single-center, single-arm objective performance criteria. This trial will be conducted with a total of 47 participants enrolled. All participants will be treated with radiation therapy using the medical device of Varian ProBeam360° Proton Therapy System (ProBeam360°), aim to compare the data with objective performance criteria (OPC) to evaluate the effectiveness and safety of ProBeam radiotherapy system for oncology patients, providing a clinical basis for the medical device registration., conditionsModule conditions: Tumor, Solid, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: prospective, open-label, non-randomized, single-arm objective performance criteria, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 47, type: ESTIMATED, armsInterventionsModule interventions name: Proton Radiation Therapy, outcomesModule primaryOutcomes measure: Effectiveness measure: tumor disease control rate reaches the objective performance criteria (80%), primaryOutcomes measure: Safety measure: Incidence of CTCAE grade 3 toxic reaction is acceptable (lower than 5%), primaryOutcomes measure: Safety measure: Incidence of CTCAE grade 4 and 5 toxic reaction is acceptable (0%), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06347692, orgStudyIdInfo id: SCBR-240/2024, briefTitle: Effect of Antigravity Treadmill in Knee Osteoarthritis (AGTreadmill), acronym: AGTreadmill, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-07, primaryCompletionDateStruct date: 2024-04-20, completionDateStruct date: 2025-04-20, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Prince Sattam Bin Abdulaziz University, class: OTHER, descriptionModule briefSummary: To date, the anti-gravity treadmill, as a representative method of lower body positive pressure treadmills, has been rarely reported for knee osteoarthritis rehabilitation.Purpose: This study aims to evaluate the effect of antigravity treadmill training on pain, gait characteristics, and function in patients with knee osteoarthritis., conditionsModule conditions: Knee Osteoarthritis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The study included 40 patients with knee osteoarthritis who were randomly assigned to one of two groups: the antigravity treadmill group (n=20) or the control group (n=20). For 12 weeks, the antigravity treadmill group received training on the Alter G treadmill (75% weight-bearing, 30 minutes per session, three times per week) combined with traditional physical therapy. During the same period, the control group received only traditional physical therapy. The Visual Analogue Scale, Walkway System, and the Western Ontario and McMaster Universities Arthritis Index were used to assess pain, spatiotemporal gait parameters, and patient function, respectively. All outcome measures were obtained pretreatment, post-treatment, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: Patients were randomly assigned to either the antigravity treadmill group (n = 20) or the control group (n = 20 ) using an online randomization website (www.randomization.com). The control group received a conventional physical therapy program. The therapists responsible for measuring and assessing the outcomes remained blinded to the group assignments., whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: antigravity treadmill, interventions name: physical therapy exercise program, outcomesModule primaryOutcomes measure: Assessment of patient pain, primaryOutcomes measure: Evaluation of gait parameters (step length), primaryOutcomes measure: Evaluation of gait parameters (step time), primaryOutcomes measure: Evaluation of gait parameters (velocity), primaryOutcomes measure: Evaluation of patient function, eligibilityModule sex: ALL, minimumAge: 50 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06347679, orgStudyIdInfo id: WCHSIRB-CT-2024-160, briefTitle: Effects of Aromatherapy on Anxiety and Pain During Dental Treatments in Adults: a Randomized Controlled Clinical Trial, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-04-01, completionDateStruct date: 2026-04-01, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Sichuan University, class: OTHER, descriptionModule briefSummary: Dental anxiety is a common problem in dental care. The aim of this protocol is to evaluate the effect of orange and tea essential oil for the control of anxiety and pain in adults during dental treatments., conditionsModule conditions: Dental Anxiety, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: Aroma diffuser with single-note sweet orange essential oil, interventions name: Aroma diffuser with single-note tea tree essential oil, interventions name: Aroma diffuser with water, outcomesModule primaryOutcomes measure: Anxiety scale 1 - Modified Dental Anxiety Scale (MDAS), primaryOutcomes measure: Pain scale - Visual Analog Scale (VAS), secondaryOutcomes measure: Anxiety scale 2 - State-Trait Anxiety Inventory for State Anxiety (STAI-S), secondaryOutcomes measure: Vital sign 1 - systolic blood pressure (SBP), secondaryOutcomes measure: Vital sign 2 - diastolic blood pressure (DBP), secondaryOutcomes measure: Vital sign 3 - heart rate (HR）, secondaryOutcomes measure: Vital sign 4 - oxygen saturation (SpO2）, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06347666, orgStudyIdInfo id: 23082905, briefTitle: Coaching in Early Development Project, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-12, primaryCompletionDateStruct date: 2025-02, completionDateStruct date: 2025-07, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Rush University Medical Center, class: OTHER, descriptionModule briefSummary: Among young children, homelessness is an independent predictor of child developmental delay and disability, and children experiencing homelessness (CEH) are 2-4x more likely to demonstrate developmental delays compared to housed children. The purpose of this project is to evaluate an evidence-based model of caregiver coaching for CEH that screen positive for developmental delay. We will also evaluate the societal costs of the program, its preliminary efficacy, and the acceptability among caregivers and shelter staff., conditionsModule conditions: Developmental Delay, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: One group will receive the caregiver coaching intervention., primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Caregiver coaching, outcomesModule primaryOutcomes measure: Parenting Sense of Competence Scale, primaryOutcomes measure: Parenting Stress Scale, secondaryOutcomes measure: Mullen Scales of Early Learning, secondaryOutcomes measure: Maternal Behavior Responsivity Scale, eligibilityModule sex: ALL, minimumAge: 12 Months, maximumAge: 6 Years, stdAges: CHILD, contactsLocationsModule locations facility: Rush University Medical Center, status: RECRUITING, city: Chicago, state: Illinois, zip: 60612, country: United States, contacts name: Lauren Little, role: CONTACT, phone: 312-942-1759, email: lauren_little@rush.edu, geoPoint lat: 41.85003, lon: -87.65005, hasResults: False
protocolSection identificationModule nctId: NCT06347653, orgStudyIdInfo id: 2023KT127, briefTitle: Linperlisib-based Treatment Regimen in Newly Diagnosed Nodal T-follicular Helper Cell Lymphoma (nTFHL), statusModule overallStatus: RECRUITING, startDateStruct date: 2023-11-28, primaryCompletionDateStruct date: 2027-01-31, completionDateStruct date: 2030-01-31, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Peking University, class: OTHER, descriptionModule briefSummary: This study is conducted to evaluate the efficacy and safety of linperlisib combined with CHOP regimen followed by autologous hematopoietic stem cell transplantation and linperlisib monotherapy maintenance for newly diagnosed nTFHL patients., conditionsModule conditions: Nodal T-follicular Helper Cell Lymphoma, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 54, type: ESTIMATED, armsInterventionsModule interventions name: linperlisib combined with CHOP regimen, outcomesModule primaryOutcomes measure: progression-free survival, secondaryOutcomes measure: ORR, secondaryOutcomes measure: CR rate, secondaryOutcomes measure: Success rate of stem cell collection, secondaryOutcomes measure: overall survival (OS), secondaryOutcomes measure: time to next anti-lymphoma treatment, secondaryOutcomes measure: adverse events, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Bejing Cancer Hospital, status: RECRUITING, city: Beijing, state: Beijing, country: China, contacts name: PING WEI LIU, master, role: CONTACT, phone: 0086-13522796323, geoPoint lat: 39.9075, lon: 116.39723, hasResults: False
protocolSection identificationModule nctId: NCT06347640, orgStudyIdInfo id: KingAbdullahUH2, briefTitle: Outcome of Pulp Revascularization of Necrotic Mature Permanent Teeth Using Platelet-rich Fibrin, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-04-01, primaryCompletionDateStruct date: 2025-12-01, completionDateStruct date: 2027-12-01, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: King Abdullah University Hospital, class: OTHER, collaborators name: Jordan University of Science and Technology, descriptionModule briefSummary: Regenerative endodontic procedures are intended to replace damaged tooth structures, including dentine and root structures, in addition to cells of the pulp-dentine complex. This treatment modality have been tested on immature necrotic teeth because they are anticipated to have a greater chance of pulp tissue regeneration.However, it has been recently suggested for treating fully formed mature necrotic permanent teeth with closed apices since the conventional root canal treatment yielded many drawbacks.A number of studies have evaluated the regeneration outcomes of using blood clot as a scaffold. However, there are limited studies in the literature on using other scaffolds such as platelet-rich fibrin (PRF).This clinical study will evaluate clinically and radiographically the effectiveness of PRF versus induced bleeding in treating mature necrotic teeth. Fifty patients with necrotic mature teeth with periapical lesions will be invited to participate in this study. Teeth will be treated using calcium hydroxide as intracanal medicament then using PRF (n=25) and blood clot (n=25) as scaffold. All teeth will be sealed coronally using NeoMTA Plus™. Treated teeth will be assessed clinically and radiographically using 2D periapical radiographs. The reported clinical and radiographic outcomes will be compared using SPSS., conditionsModule conditions: Pulp Revascularization, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized clinical trial, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: induced bleeding, interventions name: plasma rich fibrin, outcomesModule primaryOutcomes measure: Complete healing, secondaryOutcomes measure: regain the pulp sensibility, eligibilityModule sex: ALL, minimumAge: 12 Years, maximumAge: 60 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Jordan University of Science and Technology, status: RECRUITING, city: Irbid, zip: POBOX 3030, country: Jordan, contacts name: Lama A Awawdeh, role: CONTACT, phone: 0795412954, email: lawawdeh@hotmail.com, geoPoint lat: 32.55556, lon: 35.85, hasResults: False
protocolSection identificationModule nctId: NCT06347627, orgStudyIdInfo id: UW23139, briefTitle: Communicating Human Papillomavirus Vaccine With Japanese Parents and Caregivers With Daughters Aged 12-18, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2023-12-22, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: The University of Hong Kong, class: OTHER, collaborators name: London School of Hygiene and Tropical Medicine, collaborators name: Nagasaki University, descriptionModule briefSummary: This study aims to comprehensively assess confidence in and acceptance of human papillomavirus (HPV) vaccines among Japanese parents and caregivers with daughters aged 12-18 and their decision-making process., conditionsModule conditions: Healthy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: FACTORIAL, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 1600, type: ESTIMATED, armsInterventionsModule interventions name: Group 1 (I x S x S x F), interventions name: Group 2 (O x S x S x F), interventions name: Group 3 (I x E x S x F), interventions name: Group 4 (O x E x S x F), interventions name: Group 5 (I x S x S x M), interventions name: Group 6 (O x S x S x M), interventions name: Group 7 (I x E x S x M), interventions name: Group 8 (O x E x S x M), interventions name: Group 9 (I x S x D x F), interventions name: Group 10 (O x S x D x F), interventions name: Group 11 (I x E x D x F), interventions name: Group 12 (O x E x D x F), interventions name: Group 13 (I x S x D x M), interventions name: Group 14 (O x S x D x M), interventions name: Group 15 (I x E x D x M), interventions name: Group 16 (O x E x D x M), outcomesModule primaryOutcomes measure: Willingness to receive HPV vaccines for daughters, secondaryOutcomes measure: Confidence in HPV vaccine safety, eligibilityModule sex: FEMALE, minimumAge: 20 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: London School of Hygiene and Tropical Medicine, city: London, country: United Kingdom, geoPoint lat: 51.50853, lon: -0.12574, hasResults: False
protocolSection identificationModule nctId: NCT06347614, orgStudyIdInfo id: 2021-FXY-042, briefTitle: Modified Radical Prostatectomy for Prostate Cancer Patients With Enlarged Prostate and Severe Lower Urinary Tract Symptoms: a Single-center, Retrospective Study, acronym: Two-step RP, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2021-09-01, primaryCompletionDateStruct date: 2024-12-01, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Sun Yat-sen University, class: OTHER, descriptionModule briefSummary: The goal of this retrospective, observational study is to preliminarily learn about the safety and efficacy of two-step radical prostatectomy in the treatment of low- to intermediate-risk prostate cancer patients with enlarged prostate and severe benign prostatic hyperplasia. The main questions it aims to answer are: 1. Whether two-step prostatectomy is safe enough to decrease the surgical difficulty of these patients? 2. Whether the oncologic control is promising?, conditionsModule conditions: Prostate Cancer, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Two-step Radical Prostatectomy, outcomesModule primaryOutcomes measure: Biochemical Recurrence-free Survival, secondaryOutcomes measure: Surgical time, secondaryOutcomes measure: Estimated blood loss, secondaryOutcomes measure: Hospital stay, secondaryOutcomes measure: Continence ContinenceContinence Continence Continence Continence Continence Continence Continence Continence, secondaryOutcomes measure: Lower urinary tract symptoms, secondaryOutcomes measure: Erectile function, secondaryOutcomes measure: Positive surgical margin rate, secondaryOutcomes measure: Complication, eligibilityModule sex: MALE, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Sun Yat-sen University Cancer Center, city: Guangzhou, state: Guangdong, zip: 510060, country: China, geoPoint lat: 23.11667, lon: 113.25, hasResults: False
protocolSection identificationModule nctId: NCT06347601, orgStudyIdInfo id: 2024-03-011AC, briefTitle: Survey on Sexual and Gender in the Healthcare in Taiwan, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-13, primaryCompletionDateStruct date: 2025-02-01, completionDateStruct date: 2025-02-20, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: Taipei Veterans General Hospital, Taiwan, class: OTHER_GOV, descriptionModule briefSummary: This study addresses the pervasive issue of sexual harassment within Taiwanese society, particularly within the medical field, where comprehensive research is lacking. The research objective is to explore patterns of sexual harassment and gender discrimination experiences among physicians and medical students in Taiwan, while also investigating potential associations with professional burnout and mental health. Employing a convergent mixed-methods design, the study combines quantitative surveys and qualitative in-depth interviews. While lacking a control group and utilizing non-blinding methods without random assignment, the study aims to recruit 1000 participants aged 18 or older, considering both valid responses and potential dropouts. Additionally, interviews will be conducted with 30 individuals who have experienced sexual harassment or are interested in gender issues. The research methods will assess sexual harassment experiences, professional burnout, and depressive symptoms as primary outcomes or indicators., conditionsModule conditions: Sexual Harassment, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 1000, type: ESTIMATED, armsInterventionsModule interventions name: Without Intervention, outcomesModule primaryOutcomes measure: Center for Epidemiologic Studies Depression Scale, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Taipei Veterans General Hospital, status: RECRUITING, city: Taipei, zip: 100, country: Taiwan, contacts name: Jheng-Min Yu, M.D., role: CONTACT, phone: 0933238592, email: TaipeiDU2017@gmail.com, geoPoint lat: 25.04776, lon: 121.53185, hasResults: False