hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06262399, orgStudyIdInfo id: ITL-2002-CL-999, secondaryIdInfos id: 2022-003778-22, type: EUDRACT_NUMBER, briefTitle: Long-Term Follow-Up (LTFU) of Subjects Treated With NTLA 2002, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2040-04, completionDateStruct date: 2040-04, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-16, sponsorCollaboratorsModule leadSponsor name: Intellia Therapeutics, class: INDUSTRY, descriptionModule briefSummary: This is a follow-up study of subjects who received NTLA-2002 in a previous clinical trial as an observational evaluation of the long-term effects of the investigational therapy., conditionsModule conditions: Hereditary Angioedema, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, outcomesModule primaryOutcomes measure: Incidence of treatment-related Adverse Events (AEs); incidence of treatment-related Serious Adverse Events (SAEs); incidence of treatment-related Adverse Events of Special Interest (AESIs) defined per protocol, secondaryOutcomes measure: To evaluate the long-term efficacy of NTLA-2002 in previously treated subjects, secondaryOutcomes measure: Change from baseline in consumption of on-demand HAE medications for reported HAE attacks, secondaryOutcomes measure: Change from baseline in healthcare utilization for HAE attacks, secondaryOutcomes measure: Change from baseline in QoL parameters as measured by the MOXIE Angioedema-QoL instrument., secondaryOutcomes measure: Change from baseline in QoL parameters as measured by the EQ-5D-5L instrument., secondaryOutcomes measure: Change from baseline in QoL parameters as measured by the WPAI:GH instrument., eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Centre National de Reference - Grenoble, city: Grenoble, country: France, geoPoint lat: 45.16667, lon: 5.71667, locations facility: Hôpital Claude Huriez, city: Lille, country: France, geoPoint lat: 50.63297, lon: 3.05858, locations facility: New Zealand Clinical Research, city: Auckland, country: New Zealand, geoPoint lat: -36.84853, lon: 174.76349, locations facility: Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, city: Cambridge, country: United Kingdom, geoPoint lat: 52.2, lon: 0.11667, hasResults: False
protocolSection identificationModule nctId: NCT06262373, orgStudyIdInfo id: 221321, briefTitle: Angular Pregnancy - Ultrasound Definition and Correlation With Clinical Outcomes, statusModule overallStatus: COMPLETED, startDateStruct date: 2017-10-01, primaryCompletionDateStruct date: 2019-10-01, completionDateStruct date: 2019-10-01, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-16, sponsorCollaboratorsModule leadSponsor name: King's College Hospital NHS Trust, class: OTHER, descriptionModule briefSummary: The aim of this study is to establish clinically meaningful ultrasound-based diagnostic criteria for AP. To this end, the investigators will prospectively collect clinical and ultrasound data from early intrauterine pregnancies and correlate this data with pregnancy outcomes (particularly with risk of miscarriage), to establish whether there are any diagnostic criteria that can be used to make the diagnosis, facilitate increased surveillance of at risk pregnancies and reassure those with normally located pregnancies. The collected data will be used to correlate incidence of angular pregnancy and clinical variables such as maternal age, uterine fibroids, assisted conception, multiple pregnancy, ethnicity, previous uterine and adnexal surgery., conditionsModule conditions: Miscarriage in First Trimester, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 236, type: ACTUAL, armsInterventionsModule interventions name: Ultrasound, outcomesModule primaryOutcomes measure: Primary, secondaryOutcomes measure: Secondary, secondaryOutcomes measure: Secondary, eligibilityModule sex: FEMALE, minimumAge: 16 Years, maximumAge: 50 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: King's College Hospital, city: London, zip: SE5 9RS, country: United Kingdom, geoPoint lat: 51.50853, lon: -0.12574, hasResults: False
protocolSection identificationModule nctId: NCT06262347, orgStudyIdInfo id: 2024-0115, secondaryIdInfos id: UG1DA013732, type: NIH, link: https://reporter.nih.gov/quickSearch/UG1DA013732, briefTitle: Personally-Tailored Opioid-overdose and Medication for Opioid Use Disorder (MOUD) Education (TOME) for Pregnant and Postpartum Persons in MOUD, acronym: TOME, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2024-12-20, completionDateStruct date: 2025-06-20, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: T. John Winhusen, PhD, class: OTHER, collaborators name: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), collaborators name: National Institute on Drug Abuse (NIDA), descriptionModule briefSummary: The primary objective of this study is to evaluate the ability of TOME to increase Medication for Opioid Use Disorder (MOUD) and opioid-overdose knowledge in pregnant and postpartum persons., conditionsModule conditions: Opioid Use Disorder, conditions: Pregnancy Related, conditions: Substance Use, conditions: Drug Abuse, conditions: Drug Abuse in Pregnancy, conditions: Drug Addiction, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: This is an intent-to-treat, two-arm, open-label, randomized controlled trial., primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: Personally-Tailored Opioid-overdose and Medication for opioid use disorder (MOUD) Education (TOME), interventions name: Control, outcomesModule primaryOutcomes measure: Medication for Opioid Use Disorder (MOUD) knowledge score, primaryOutcomes measure: Opioid Overdose knowledge score, secondaryOutcomes measure: Medication for Opioid Use Disorder (MOUD) Internalized Stigma, secondaryOutcomes measure: Drug Self-efficacy, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06262321, orgStudyIdInfo id: URLUN23099, briefTitle: Thoracic Radiotherapy for Patients With Metastatic (Stage IV) Non-Small Cell Lung Cancer at High Risk of Symptomatic Progression Within the Thorax, acronym: DRO2301, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2029-02-01, completionDateStruct date: 2029-02-01, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: University of Rochester, class: OTHER, descriptionModule briefSummary: Patients with metastatic non small cell lung cancer with high risk location or size are treated with prophylactic radiation therapy in conjunction with standard of care systemic therapy., conditionsModule conditions: Stage 4 NSCLC, conditions: Radiotherapy, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 48, type: ESTIMATED, armsInterventionsModule interventions name: Prophylactic Palliative Radiotherapy, outcomesModule primaryOutcomes measure: Freedom from symptomatic progression of irradiated thoracic target(s), secondaryOutcomes measure: OS (Kaplan-Meier) (Kaplan-Meier), secondaryOutcomes measure: Freedom from local recurrence of irradiated thoracic target lesion(s), secondaryOutcomes measure: PFS (freedom from local and distant progression; Kaplan-Meier), secondaryOutcomes measure: Duration of time that patient is maintenance, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06262308, orgStudyIdInfo id: 334235, briefTitle: Emotional Support for Women Experiencing PPROM, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2025-03, completionDateStruct date: 2025-03, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-16, sponsorCollaboratorsModule leadSponsor name: King's College London, class: OTHER, descriptionModule briefSummary: Preterm Prelabour Rupture of the Membranes is a pregnancy complication affecting 3% of all pregnancies. Outcomes for both the mother and baby are variable including: preterm delivery, fetal infection, cord prolapse, abruption as well as maternal sepsis and even maternal death. The outcomes are not only variable but the stress and uncertainty can be over a protracted period of time. This is a pilot study that aims to provide personalised psychological intervention at the time of PPROM based on Cognitive Behavioural Principles to see whether this improves psychological outcomes for women., conditionsModule conditions: Fetal Membranes, Premature Rupture, conditions: Preterm Birth Complication, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: This is a pilot study where a small cohort of women will give given personalised psychological intervention, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 8, type: ESTIMATED, armsInterventionsModule interventions name: Psychological intervention along Cognitive Behavioural Therapy principles, outcomesModule primaryOutcomes measure: Mood Score 1, primaryOutcomes measure: Mood Score 2, primaryOutcomes measure: Participant Feedback, eligibilityModule sex: FEMALE, minimumAge: 16 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: St Thomas' Hospital, King's College London, city: London, state: Greater London, zip: SE1 7EH, country: United Kingdom, geoPoint lat: 51.50853, lon: -0.12574, hasResults: False
protocolSection identificationModule nctId: NCT06262295, orgStudyIdInfo id: 2023-A02475-40, briefTitle: National, Observational Registry for Comprehensive Follow-up of All Implementations of the AVEIR VR LP Device in France (France LEADLESS), statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-02, primaryCompletionDateStruct date: 2027-09, completionDateStruct date: 2027-09, studyFirstPostDateStruct date: 2024-02-16, lastUpdatePostDateStruct date: 2024-02-16, sponsorCollaboratorsModule leadSponsor name: French Cardiology Society, class: OTHER, collaborators name: Abbott, descriptionModule briefSummary: Although the idea of a leadless pacemaker was first proposed in the 1970s to eliminate the probes, pockets and connectors required by conventional cardiac procedures and the associated complications, the first devices were not developed until the late 2010s. Leadless pacemakers can also improve patient comfort by replacing surgery with a percutaneous procedure, eliminating the mass and scar visible at the implantation site of a conventional pacemaker, and eliminating the need for activity restrictions to prevent dislodgement after implantation of a conventional lead.The AVEIR VR LP leadless pacemaker was CE marked in July 2023 and will be implanted in patients in Europe.The objective of this national registry is to evaluate the safety and performance of the AVEIR VR LP system in a population of patients indicated for implantation of a VVI(R) pacemaker in France. This registry will also allow the collection of patient characteristics and indications under normal conditions of use., conditionsModule conditions: Pacemaker, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 400, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: To confirm the safety of the AVEIR VR LP device, primaryOutcomes measure: To confirm the effectiveness of the AVEIR VR LP device, primaryOutcomes measure: To collect patient characteristics and indications in normal conditions of use of the AVEIR VR LP device, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06262256, orgStudyIdInfo id: HIIT-GLS-METS, briefTitle: Effects of High-intensity Interval Training on Myocardial Strain in Metabolic Syndrome Patients, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-09-01, primaryCompletionDateStruct date: 2023-05-30, completionDateStruct date: 2023-12-22, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-02-15, sponsorCollaboratorsModule leadSponsor name: University of Castilla-La Mancha, class: OTHER, collaborators name: Complejo Hospitalario de Toledo, descriptionModule briefSummary: the effects of high-intensity interval training on myocardial function will be studied in a group of patients under medical treatment for the components of metabolic syndrome., conditionsModule conditions: High-Intensity Interval Training, conditions: Metabolic Syndrome, conditions: Myocardial Dysfunction, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized clinical trial with control group, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: Echocardiography evaluators will be masked about participant allocation., whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 80, type: ACTUAL, armsInterventionsModule interventions name: High-intensity interval training, outcomesModule primaryOutcomes measure: Changes in global longitudinal strain, secondaryOutcomes measure: changes in cardiorespiratory fitness, secondaryOutcomes measure: changes in metabolic syndrome z-score, secondaryOutcomes measure: changes in visceral fat, secondaryOutcomes measure: changes in left ventricle passive filling (E wave), secondaryOutcomes measure: changes in early diastolic mitral annulus velocity (e' wave), secondaryOutcomes measure: changes in estimated left ventricle filling pressures (E/e'), eligibilityModule sex: ALL, minimumAge: 30 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Castilla-La Mancha, city: Toledo, state: Castilla-La Mancha, zip: 45071, country: Spain, geoPoint lat: 39.8581, lon: -4.02263, hasResults: False
protocolSection identificationModule nctId: NCT06262243, orgStudyIdInfo id: ORDUU-HEM-TÇ-01, briefTitle: The Effect of Heating With Electrical Blanket After Cesarean Section on the Postpartum, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-15, primaryCompletionDateStruct date: 2024-08-30, completionDateStruct date: 2024-09-01, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-02-15, sponsorCollaboratorsModule leadSponsor name: T.C. ORDU ÜNİVERSİTESİ, class: OTHER, descriptionModule briefSummary: It is known that maintaining and maintaining normal body temperature in women after cesarean section facilitates the mother's adaptation to the postpartum period. One of the important problems after cesarean section is hypothermia. Therefore, various methods are used to maintain normal body temperature. One of these methods is the use of electric blankets. This study will investigate the effect of using electric blankets after cesarean section on postpartum comfort, pain, milk quantity and breastfeeding success., conditionsModule conditions: Cesarean Section, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The research is a randomized controlled experimental design., primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: SINGLE, maskingDescription: In this randomized controlled study, 78 mothers, 39 in each group, will be included in the intervention and control groups that meet the criteria for participation in the study. The researcher will give general information about the research to the mothers in the intervention and control groups during hospitalization and nurse admission, and their written informed consent will be obtained., whoMasked: PARTICIPANT, enrollmentInfo count: 78, type: ESTIMATED, armsInterventionsModule interventions name: electric blankets, outcomesModule primaryOutcomes measure: Postpartum comfort scale, primaryOutcomes measure: A Tool to Evaluate the Amount of Breast Milk the Baby Receives, secondaryOutcomes measure: Bristol Breastfeeding Assessment Tool, secondaryOutcomes measure: Insufficient Milk Perception Scale, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Samsun Training and Research Hospital, status: RECRUITING, city: Samsun, state: İ̇lkadim, zip: 55080, country: Turkey, contacts name: TUBA ÇITAK, role: CONTACT, phone: 05349265496, email: tubadlkc@gmail.com, contacts name: Ebru ŞAHİN, role: SUB_INVESTIGATOR, contacts name: Tuba ÇITAK, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 41.27976, lon: 36.3361, hasResults: False
protocolSection identificationModule nctId: NCT06262230, orgStudyIdInfo id: OPCI on ASD Children, briefTitle: Feasibility and Effectiveness of OPCI on ASD Children, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-11-20, primaryCompletionDateStruct date: 2023-10-31, completionDateStruct date: 2023-10-31, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-02-15, sponsorCollaboratorsModule leadSponsor name: Peking University, class: OTHER, descriptionModule briefSummary: The goal of this interventional study was to explore the feasibility and effectiveness of online peer companion intervention (OPCI) on the social abilities and mental health of ASD children. The main questions it aims to answer are:1. What is the acceptability and adherence of OPCI;2. Whether OPCI is effective on the social abilities and mental health of ASD children;3. What impact does OPCI have on ordinary children and parents of both children?, conditionsModule conditions: Autism Spectrum Disorder, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: In this study, ordinary children will be paired with ASD children according to age, hobbies and other conditions, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ACTUAL, armsInterventionsModule interventions name: Online Inclusive Companionship Intervention, outcomesModule primaryOutcomes measure: Social Behavior of ASD Children, primaryOutcomes measure: Mental Health of ASD Children, primaryOutcomes measure: Intervention Process Screen Recording Coding, primaryOutcomes measure: Symptom Severity, secondaryOutcomes measure: Mental Health of Ordinary Children, secondaryOutcomes measure: Social Ability of Ordinary Children, secondaryOutcomes measure: Mental Health of Parents, eligibilityModule sex: ALL, minimumAge: 7 Years, maximumAge: 15 Years, stdAges: CHILD, contactsLocationsModule locations facility: Peking University, city: Beijing, state: Beijing, zip: 100871, country: China, geoPoint lat: 39.9075, lon: 116.39723, hasResults: False
protocolSection identificationModule nctId: NCT06262217, orgStudyIdInfo id: INGN21ST510, briefTitle: Mobile MRI for Immediate Radiological Acute Cerebral Lesion Evaluation in Stroke, acronym: MIRACLES, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-11-11, primaryCompletionDateStruct date: 2024-05-31, completionDateStruct date: 2024-08-01, studyFirstPostDateStruct date: 2024-02-15, lastUpdatePostDateStruct date: 2024-02-15, sponsorCollaboratorsModule leadSponsor name: NHS Greater Glasgow and Clyde, class: OTHER, collaborators name: University of Glasgow, descriptionModule briefSummary: This prospective observational study will evaluate the potential value of mobile MRI in patients with suspected or proven acute stroke and Transient Ischemic Attack (TIA), undertaking additional imaging in the emergency department, acute stroke unit, or outpatient settings, and comparing diagnostic accuracy, Diffusion-weighted imaging (DWI) lesion volume and detection of complications (brain swelling or haemorrhagic transformation). Information on ease of use, tolerability and image quality will also be gathered., conditionsModule conditions: Stroke, Acute, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: Mobile MRI scanner, outcomesModule primaryOutcomes measure: Diagnostic sensitivity and specificity of mobile MRI scanner, secondaryOutcomes measure: Comparison of MRI abnormalities, secondaryOutcomes measure: Final Clinical Diagnosis, secondaryOutcomes measure: Final Clinical Diagnosis, secondaryOutcomes measure: Time from arrival at the Emergency Department to scan, secondaryOutcomes measure: Use of treatments, secondaryOutcomes measure: Patient Outcomes, secondaryOutcomes measure: Level of confidence in final diagnosis, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Queen Elizabeth University Hospital, status: RECRUITING, city: Glasgow, country: United Kingdom, contacts name: Stewart Rodney, role: CONTACT, phone: 0141 451 6879, email: stewart.rodney@glasgow.ac.uk, geoPoint lat: 55.86515, lon: -4.25763, hasResults: False