hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06377527, orgStudyIdInfo id: 2023-0945, secondaryIdInfos id: NCI-2024-03342, type: OTHER, domain: NCI-CTRP Clinical Registry, briefTitle: Establishing a Tumor Registry of Patients With Mesonephric-like Adenocarcinoma (MLA), statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-10-31, primaryCompletionDateStruct date: 2035-12-28, completionDateStruct date: 2037-12-28, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: M.D. Anderson Cancer Center, class: OTHER, descriptionModule briefSummary: To develop a database of medical information about patients with MLA in an effort to increase our understanding of the characteristics of MLA, which is the rarest form of endometrial carcinoma., conditionsModule conditions: Mesonephric-like Adenocarcinoma, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: OTHER, enrollmentInfo count: 2000, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Tumor Registry, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: MD Anderson Cancer Center, city: Houston, state: Texas, zip: 77030, country: United States, contacts name: Jeffrey How, MD, role: CONTACT, contacts name: Jeffrey How, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 29.76328, lon: -95.36327, hasResults: False
protocolSection identificationModule nctId: NCT06377514, orgStudyIdInfo id: PCOL109PHNG, briefTitle: Clinical Investigation of the TECNIS® Next-Generation Intraocular Lens, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2025-10-31, completionDateStruct date: 2025-10-31, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Johnson & Johnson Surgical Vision, Inc., class: INDUSTRY, descriptionModule briefSummary: Prospective, multicenter, bilateral, interventional, controlled, masked (sponsor, subjects, and evaluators), randomized clinical trial., conditionsModule conditions: Cataracts, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 250, type: ESTIMATED, armsInterventionsModule interventions name: Test IOL Model DEN00V, interventions name: Control IOL Model DCB00, outcomesModule primaryOutcomes measure: Monocular photopic DCIVA (first eyes) at 66 cm, primaryOutcomes measure: Monocular Depth of Focus, primaryOutcomes measure: Monocular Photopic BCDVA at 4m, primaryOutcomes measure: Monocular Photopic DCVA at 100 cm, secondaryOutcomes measure: Monocular photopic DCNVA at 40 cm (first eyes), eligibilityModule sex: ALL, minimumAge: 22 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06377501, orgStudyIdInfo id: 804687, briefTitle: Feasibility of a Whole-Food, Plant-Based Diet for Patients With Low-Risk Chronic Lymphocytic Leukemia (CLL), statusModule overallStatus: RECRUITING, startDateStruct date: 2023-03-07, primaryCompletionDateStruct date: 2024-07-01, completionDateStruct date: 2024-07, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: University of California, San Diego, class: OTHER, descriptionModule briefSummary: This study will evaluate the feasibility of an 8-week vegan whole-food, plant-based dietary intervention in subjects with low risk CLL who are undergoing observation. Over the course of 8 weeks, participants will attend weekly group cooking classes via Zoom lead by a RD. Participants will also attend weekly individual meetings with a health coaches to assist with adherence to the dietary intervention., conditionsModule conditions: Chronic Lymphocytic Leukemia Stage A(0), designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 18, type: ESTIMATED, armsInterventionsModule interventions name: Whole-food, plant-based diet, outcomesModule primaryOutcomes measure: Adherence to the Dietary Intervention, primaryOutcomes measure: Satisfaction with the Dietary Intervention, primaryOutcomes measure: Cooking Class Adherence, primaryOutcomes measure: Recruitment, primaryOutcomes measure: Retention, secondaryOutcomes measure: White blood cell count, secondaryOutcomes measure: Absolute lymphocyte count, secondaryOutcomes measure: Anthropometric Measures (height, weight, body mass index), secondaryOutcomes measure: Anthropometric Measures (waist circumference), secondaryOutcomes measure: Biomarkers of cardiometabolic health (complete metabolic panel), secondaryOutcomes measure: Biomarkers of cardiometabolic health (hemoglobin A1c), secondaryOutcomes measure: Biomarkers of cardiometabolic health (cholesterol and triglycerides), secondaryOutcomes measure: Concentration of vitamin B12, secondaryOutcomes measure: Concentration of vitamin B9, secondaryOutcomes measure: Concentration of iron, secondaryOutcomes measure: Concentration of ferritin, secondaryOutcomes measure: Blood pressure, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: UC San Diego, status: RECRUITING, city: San Diego, state: California, zip: 92093, country: United States, contacts name: Ariel Portera, DO, role: CONTACT, phone: 858-249-6896, email: aportera@health.ucsd.edu, geoPoint lat: 32.71533, lon: -117.15726, documentSection largeDocumentModule largeDocs typeAbbrev: ICF, hasProtocol: False, hasSap: False, hasIcf: True, label: Informed Consent Form, date: 2023-02-23, uploadDate: 2024-04-17T18:09, filename: ICF_000.pdf, size: 514422, hasResults: False
protocolSection identificationModule nctId: NCT06377475, orgStudyIdInfo id: 2024-00148, secondaryIdInfos id: 2024-00148, type: REGISTRY, domain: EKNZ, briefTitle: Fabrication and Insertion of Michigan Splints by Dental Students, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2024-03-08, primaryCompletionDateStruct date: 2024-05, completionDateStruct date: 2025-12, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Juliana Marotti Großhausen, class: OTHER, descriptionModule briefSummary: The aim of this study is to investigate the potential effects of different jaw relation determination (KRB) techniques on the fabrication of Michigan splints, in particular by comparing conventional methods with a wax plate and the use of an anterior jig. All materials and methods for the fabrication of the Michigan splint are already part of the curriculum of the Clinic for Dental Prosthodontics for first-year Master-students. Therefore, we intend to conduct a retrospective study (for the 2023 cohort) and a prospective analysis of the data (for the 2024 and 2025 cohorts). Questionnaires, models and intraoral scans will be used to evaluate the efficacy and precision of the different KRB methods as well as the fabrication process of the Michigan splint., conditionsModule conditions: Impression Technic, Dental, conditions: Jaw Relationship, conditions: Bruxism, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 73, type: ESTIMATED, armsInterventionsModule interventions name: Jaw relation, interventions name: Questionnaire, outcomesModule primaryOutcomes measure: Wax vs JIG Registration, secondaryOutcomes measure: Questionnaire, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: UZB, city: Basel, zip: 4058, country: Switzerland, geoPoint lat: 47.55839, lon: 7.57327, hasResults: False
protocolSection identificationModule nctId: NCT06377462, orgStudyIdInfo id: VEXAS-Registry, briefTitle: Multicenter, Interdisciplinary National VEXAS Registry With Accompanying Biomaterial Collection, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-13, primaryCompletionDateStruct date: 2029-12-31, completionDateStruct date: 2030-12-31, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Technische Universität Dresden, class: OTHER, collaborators name: Bristol-Myers Squibb, collaborators name: University Hospital Munich, descriptionModule briefSummary: The aim is rapid collection of real-life data on the epidemiology, treatment and disease course in patients with VEXAS syndrome during routine clinical practice and collect biomaterials to evaluate genotype-phenotype associations, determine optimal treatment schedule, identify diagnostic features and biomarkers, conditionsModule conditions: VEXAS Syndrome, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 500, type: ESTIMATED, outcomesModule primaryOutcomes measure: Collection of epidemiological data on VEXAS, primaryOutcomes measure: Collection and monitoring of initial disease manifestations, primaryOutcomes measure: Documentation of the treatment approaches and therapy sequences, primaryOutcomes measure: Analysis of clinical-relevant clinical endpoints, secondaryOutcomes measure: Describe disease cluster, secondaryOutcomes measure: Laboratory diagnostics, secondaryOutcomes measure: Correlation clinical endpoints with treatment approaches, secondaryOutcomes measure: Quality of life data (QoL), fatigue questionnaire (Facit-F), secondaryOutcomes measure: Accompanying translational research, secondaryOutcomes measure: Collection of Biospecimens, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Universitätsklinikum Carl Gustav Carus, status: RECRUITING, city: Dresden, zip: 01307, country: Germany, contacts name: Katja Sockel, Dr. med., role: CONTACT, geoPoint lat: 51.05089, lon: 13.73832, hasResults: False
protocolSection identificationModule nctId: NCT06377436, orgStudyIdInfo id: PRAISE, briefTitle: Prevention of Disability in the Frail Elderly Person Through an Innovative Customised and Multidimensional Training Programme, acronym: PRAISE, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-03-20, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: University of Milan, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to implement a personalized training program to prevent functional decline in frail subjects but not yet disable. The purpose of the project is to test the training in a subject at particularly high risk of entering the disabled condition. A total of 80 frail subjects, divide the participants into two groups "Divida Senso Group" (experimental group) and "Standard of care Group" (Control group) will be recruited.The expected outcome is to slow down a functional decline not only in isolation in the domains trained by the program., conditionsModule conditions: Frailty, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Experimental training, outcomesModule primaryOutcomes measure: Changes in the Functional decline, primaryOutcomes measure: Intrinsic Capacity (IC), primaryOutcomes measure: Intreaction between IC and cardiac autonomic control (CAC), eligibilityModule sex: ALL, minimumAge: 65 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Gabriella CERRI, status: RECRUITING, city: Milano, zip: 20100, country: Italy, contacts name: Gabriella GC CERRI, Full Professor, role: CONTACT, phone: +393402527675, email: gabriella.cerri@unimi.it, geoPoint lat: 45.46427, lon: 9.18951, hasResults: False
protocolSection identificationModule nctId: NCT06377423, orgStudyIdInfo id: A54678775, briefTitle: Comparison Between Direct Composite and Indirect Ceramic Laminate Veneers in Multiple Diastema Closure Cases, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-08-01, primaryCompletionDateStruct date: 2024-01-01, completionDateStruct date: 2024-01-10, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Prince Sattam Bin Abdulaziz University, class: OTHER, descriptionModule briefSummary: Thus, the present study aimed to evaluate the longevity of direct composite compared to indirect ceramic laminate veneers in multiple diastema closure cases using USPHS criteria. The formulated null hypothesis was that there is no significant difference in the clinical performance of direct composite and indirect ceramic laminate veneers in multiple diastema closure cases over two years., conditionsModule conditions: Dental Leakage, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 28, type: ACTUAL, armsInterventionsModule interventions name: Direct technique, interventions name: Indirect technique, outcomesModule primaryOutcomes measure: Percentage % of patients with marginal staining, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 35 Years, stdAges: ADULT, contactsLocationsModule locations facility: Ali Elkaffas, city: Al Kharj, country: Saudi Arabia, geoPoint lat: 24.15541, lon: 47.33457, hasResults: False
protocolSection identificationModule nctId: NCT06377384, orgStudyIdInfo id: DHP-33-FLIGHT, briefTitle: FLIGHT Study for Childhood Chronic Illness, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-04-20, primaryCompletionDateStruct date: 2025-09, completionDateStruct date: 2025-09, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Documenting Hope Project, class: OTHER, descriptionModule briefSummary: The FLIGHT study is an open-label, single-arm, pilot and feasibility study of a personalized and multimodality intervention focusing upon modifiable lifestyle factors, environmental modifications, and transdisciplinary clinical care for children with chronic illness. A mixed methods outcomes evaluation will be performed. The primary goal of this study is to evaluate the most feasible and promising strategies to inform a more streamlined and scalable intervention in the future. Up to 14 participants may be enrolled, but fewer are expected to achieve the primary goal of the study., conditionsModule conditions: Chronic Illnesses, Multiple, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 14, type: ESTIMATED, armsInterventionsModule interventions name: FLIGHT Intervention, outcomesModule primaryOutcomes measure: Total Load Index (TLI), secondaryOutcomes measure: Child Health Inventory for Resilience and Prevention (CHIRP), secondaryOutcomes measure: Children's Sleep Habits Questionnaire (CSHQ), secondaryOutcomes measure: Vineland Adaptive Behavior Scale, secondaryOutcomes measure: Sensory Profile 2, secondaryOutcomes measure: Quick Environmental Exposure and Sensitivity Inventory (QEESI), secondaryOutcomes measure: Hayward Environmental Illness Severity Scale, secondaryOutcomes measure: Parenting Stress Index, 4th edition (PSI-4), secondaryOutcomes measure: Beck Anxiety Inventory (BAI), eligibilityModule sex: ALL, minimumAge: 2 Years, maximumAge: 15 Years, stdAges: CHILD, contactsLocationsModule locations facility: Epidemic Answers, status: RECRUITING, city: Windsor, state: Connecticut, zip: 06095, country: United States, contacts name: Study Coordinator, role: CONTACT, phone: 833-935-5543, email: info@epidemicanswers.org, geoPoint lat: 41.8526, lon: -72.6437, hasResults: False
protocolSection identificationModule nctId: NCT06377371, orgStudyIdInfo id: 23-03025815, briefTitle: Feasibility of Intraoperative Tracing of Meningioma Using [Cu64]DOTATATE, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-01, completionDateStruct date: 2025-01, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Weill Medical College of Cornell University, class: OTHER, collaborators name: Curium US LLC, descriptionModule briefSummary: The study team hypothesizes that it is feasible to intraoperatively detect tumor following \[CU64\]DOTATATE injection using the gamma probe device., conditionsModule conditions: Meningioma, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: Brain Imaging with [Cu64]DOTATATE, interventions name: Radio-guided Surgery With Neoprobe Utilization, outcomesModule primaryOutcomes measure: Preoperative [Cu64]DOTATATE PET SUV, primaryOutcomes measure: 1st Post-operative [Cu64]DOTATATE PET SUV, primaryOutcomes measure: 2nd Post-operative [Cu64]DOTATATE PET SUV, primaryOutcomes measure: MRI Size Measurements, primaryOutcomes measure: GTR vs STR Assessment, primaryOutcomes measure: MRI Progression Assessment, primaryOutcomes measure: Target Lesion Neoprobe Count, primaryOutcomes measure: Subtotal Neoprobe Count, primaryOutcomes measure: Reference Background Neoprobe Count, secondaryOutcomes measure: SSTR2 expression, secondaryOutcomes measure: WHO grade, secondaryOutcomes measure: Ki67 Proliferation Index, secondaryOutcomes measure: ER/PR expression, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 99 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: New York-Presbyterian/Weill Cornell Medical Center, city: New York, state: New York, zip: 10021, country: United States, geoPoint lat: 40.71427, lon: -74.00597, hasResults: False
protocolSection identificationModule nctId: NCT06377319, orgStudyIdInfo id: 101080905, briefTitle: Decision Support System for Diagnosis and Progression of Heart Failure, acronym: STRATIFYHF, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-07-01, primaryCompletionDateStruct date: 2027-07-31, completionDateStruct date: 2027-07-31, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Coventry University, class: OTHER, collaborators name: Newcastle University, collaborators name: University of Cambridge, collaborators name: University of Novi Sad, collaborators name: University of Florence, collaborators name: University of Regensburg, collaborators name: Utrecht University, collaborators name: Servicio Madrileño de Salud, Madrid, Spain, descriptionModule briefSummary: Heart failure (HF) is a complex clinical syndrome associated with impaired heart function, poor quality of life for patients and high healthcare costs. Accurate risk stratification and early diagnosis in HF are challenging as signs and symptoms are non-specific. Here the investigators propose to address this global challenge by developing novel analytic methods for HF (STRATIFYHF). A prospective clinical study will collect patient-specific data related to medical history, a physical examination for signs and symptoms, blood tests including natriuretic peptides, an electrocardiogram (ECG), an echocardiogram (ultrasound of the heart), cardiovascular magnetic resonance imaging (MRI), demographic, socio-economic and lifestyle data along with novel technologies (cardiac output response to stress (CORS) test and voice recognition biomarkers) from individuals at-risk of developing HF and those with a confirmed diagnosis of HF. STRATIFYHF will use these data to support clinical validation of an artificial intelligence (AI)-driven decision support system (DSS) and mobile application for risk prediction, diagnosis, and progression of HF to enhance patients' quality of life and lead to more cost-effective health care., conditionsModule conditions: Heart Failure, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 1600, type: ESTIMATED, armsInterventionsModule interventions name: Cardiac Output Response to Stress (CORS) test, outcomesModule primaryOutcomes measure: Diagnostic accuracy of the DSS, secondaryOutcomes measure: Demographic and clinical predictors of risk, diagnosis, and progression of heart failure., eligibilityModule sex: ALL, minimumAge: 45 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06377280, orgStudyIdInfo id: NAV-0011, briefTitle: En Evaluation of Navina Mini, a New Low-volume Transanal Irrigation Device., statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-18, primaryCompletionDateStruct date: 2024-10, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Wellspect HealthCare, class: INDUSTRY, descriptionModule briefSummary: This is an un-controlled, prospective, multi center, post market clinical follow-up investigation that will enroll male and female subjects in need of bowel management with low-volume transanal irrigation (TAI) as judged by the investigator. A total of 40 investigational subjects in need of low-volume TAI will be recruited from 2-3 sites in Sweden and will be treated with Navina Mini as per product intended purpose and per instruction of use during a period of four weeks.Participating subjects will perform three visits during the clinical investigation and will be followed for a total of four weeks. The first visit, Visit 1, will be performed at the investigational clinic to assess eligibility, collect demographics, baseline data and instruct how to use the device. Visit 2 will be performed after two weeks of treatment through telephone contact. The final visit, Visit 3, will be performed after additional two weeks of treatment, and can be performed either at the investigational clinic or through telephone contact., conditionsModule conditions: Bowel Dysfunction, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Navina Mini, outcomesModule primaryOutcomes measure: Patient satisfaction, secondaryOutcomes measure: Assessment of clinical benefit, secondaryOutcomes measure: Ease of handling, secondaryOutcomes measure: Safety Outcome, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Skåne University Hospital, status: RECRUITING, city: Malmö, country: Sweden, contacts name: Louis Banka Johnson, MD, role: CONTACT, phone: +4640336557, email: louis_banka.johnson@med.lu.se, contacts name: Sara Strandberg, role: CONTACT, phone: +4640336377, email: sara.strandberg@skane.se, geoPoint lat: 55.60587, lon: 13.00073, hasResults: False