hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06350773, orgStudyIdInfo id: FMBSUREC/06122022/ Zaher, briefTitle: Phosphodiesterase Type 5 Inhibitors in Patients With Group 2 Pulmonary Hypertension, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-01-10, primaryCompletionDateStruct date: 2024-07, completionDateStruct date: 2024-11, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-08, sponsorCollaboratorsModule leadSponsor name: Beni-Suef University, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to test the efficacy of tadalafil in patients with group II pulmonary hypertension with elevated pulmonary vascular resistance (PVR). The main question it aims to answer is:• Can tadalafil improve patients with group II pulmonary hypertension with elevated PVR? Participants will undergo right heart catheterization (RHC) to make sure they are fulfilling the inclusion criteria, then will be asked to take tadalafil 20 mg for two weeks then 40 mg if tolerated for 12 weeks, then participants will be followed up. Investigators will compare the drug group with another age- and sex- matched control placebo group., conditionsModule conditions: Group 2 Pulmonary Hypertension, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 48, type: ESTIMATED, armsInterventionsModule interventions name: tadalafil 20 mg then 40 mg if tolerated, outcomesModule primaryOutcomes measure: Functional capacity of the patients, primaryOutcomes measure: heart failure symptoms, secondaryOutcomes measure: right ventricular function, secondaryOutcomes measure: right ventricular function, secondaryOutcomes measure: right ventricular function, secondaryOutcomes measure: right ventricular function, secondaryOutcomes measure: right ventricular function, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Beni Suef University, status: RECRUITING, city: Cairo, state: Beni Suef, zip: 62511, country: Egypt, contacts name: Hesham Boshra Mahmoud, Doctorate, role: CONTACT, phone: 201001402250, email: heshamboshra@gmail.com, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06350747, orgStudyIdInfo id: CelalBayarU-SBF-OT-02, briefTitle: The Effect of Laughter Yoga on Nurses' Perceived Stress, Sleep Quality, and Burnout Levels, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-07-01, completionDateStruct date: 2024-07-30, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-18, sponsorCollaboratorsModule leadSponsor name: Celal Bayar University, class: OTHER, descriptionModule briefSummary: The aim of the study was to investigate the effects of laughter yoga on nurses' perceived stress, sleep quality, and burnout levels., conditionsModule conditions: Healthy Participants, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: pretest-posttest with control group, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 64, type: ESTIMATED, armsInterventionsModule interventions name: Laughter Yoga, outcomesModule primaryOutcomes measure: Perceived Stress Scale, primaryOutcomes measure: Jenkins Sleep Scale, primaryOutcomes measure: Maslach Burnout Scale, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Manisa Celal Bayar Üniversitesi Hafsa Sultan Hastanesi, status: RECRUITING, city: Manisa, zip: 45060, country: Turkey, contacts name: Özge Topsakal, PhD, role: CONTACT, phone: 05549165599, email: ozgebydr_19@hotmail.com, geoPoint lat: 38.61202, lon: 27.42647, hasResults: False
protocolSection identificationModule nctId: NCT06350734, orgStudyIdInfo id: 18-004675, secondaryIdInfos id: NCI-2024-00973, type: REGISTRY, domain: CTRP (Clinical Trial Reporting Program), secondaryIdInfos id: 18-004675, type: OTHER, domain: Mayo Clinic Institutional Review Board, briefTitle: Quality of Life After Treatment for Bladder Cancer: The Bladder Cancer Survivorship Study, statusModule overallStatus: RECRUITING, startDateStruct date: 2018-10-12, primaryCompletionDateStruct date: 2029-01-31, completionDateStruct date: 2029-01-31, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Mayo Clinic, class: OTHER, descriptionModule briefSummary: This study evaluates the effect of bladder cancer treatment on quality of life., conditionsModule conditions: Stage 0a Bladder Cancer AJCC v8, conditions: Stage 0is Bladder Cancer AJCC v8, conditions: Stage I Bladder Cancer AJCC v8, conditions: Stage II Bladder Cancer AJCC v8, conditions: Stage IIIA Bladder Cancer AJCC v8, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 704, type: ESTIMATED, armsInterventionsModule interventions name: Non-Interventional Study, outcomesModule primaryOutcomes measure: Change in quality of life outcomes - PROMIS-29, primaryOutcomes measure: Change in quality of life outcomes - Bladder Cancer Index, primaryOutcomes measure: Patient level characteristics, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Mayo Clinic in Arizona, status: RECRUITING, city: Scottsdale, state: Arizona, zip: 85259, country: United States, contacts name: Clinical Trials Referral Office, role: CONTACT, phone: 855-776-0015, email: mayocliniccancerstudies@mayo.edu, contacts name: Mark D. Tyson, M.D., M.P.H., role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 33.50921, lon: -111.89903, locations facility: Mayo Clinic in Florida, status: RECRUITING, city: Jacksonville, state: Florida, zip: 32224-9980, country: United States, contacts name: Clinical Trials Referral Office, role: CONTACT, phone: 855-776-0015, email: mayocliniccancerstudies@mayo.edu, contacts name: Paul R. Young, M.D., role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 30.33218, lon: -81.65565, locations facility: Mayo Clinic in Rochester, status: RECRUITING, city: Rochester, state: Minnesota, zip: 55905, country: United States, contacts name: Clinical Trials Referral Office, role: CONTACT, phone: 855-776-0015, email: mayocliniccancerstudies@mayo.edu, contacts name: Matthew T. Gettman, M.D., role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 44.02163, lon: -92.4699, hasResults: False
protocolSection identificationModule nctId: NCT06350721, orgStudyIdInfo id: DizzyVR, briefTitle: Feasibility, Usability and Safety of the Vestibular Rehabilitation Using the Immersive Virtual Reality Software DizzyVR, acronym: DizzyVR, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-06-01, completionDateStruct date: 2024-10-01, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Universidad Loyola Andalucia, class: OTHER, collaborators name: University of Seville, collaborators name: Universitat Politècnica de València, collaborators name: Universidad de Zaragoza, descriptionModule briefSummary: The goal of this pilot study is to assess the safety and feasibility of the immersive virtual reality system called DizzyVR in participants diagnosed with a vestibular disorder. The main questions it aims to answer are:* To assess the feasibility, usability and safety of the system DizzyVR for the vestibular rehabilitation in participants with vestibular disorders.* To detect and record possible adverse events due to the use of DizzyVR.* To examine the degree of adherence of the participants to the intervention.* To know the average success rate of the different games in each session.* To evaluate the average difficulty levels overcome throughout the intervention.* To know the usability and satisfaction with the system reported by participants and therapists.Participants will receive the vestibular rehabilitation based on the novel immersive virtual systema, DizzyVR., conditionsModule conditions: Vestibular Disorder, conditions: Physical Disability, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: DEVICE_FEASIBILITY, maskingInfo masking: NONE, enrollmentInfo count: 10, type: ESTIMATED, armsInterventionsModule interventions name: DizzyVR, outcomesModule primaryOutcomes measure: Retention rate of participants, primaryOutcomes measure: User Satisfaction Evaluation Questionnaire (USEQ), primaryOutcomes measure: Register of risk and number of adverse events experimented by the stakeholders, primaryOutcomes measure: Adherence rate, primaryOutcomes measure: Dropout rates, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06350708, orgStudyIdInfo id: 2024-18304-33663, secondaryIdInfos id: 336664, type: OTHER, domain: Integrated Research Application System (IRAS), briefTitle: Virtual Reality (VR) Paediatric Tracheostomy Training, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-07-10, completionDateStruct date: 2024-07-10, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: University of Manchester, class: OTHER, descriptionModule briefSummary: This study aims to evaluate the use of an unsupervised virtual reality training tool. This tool is used to teach nurses, doctors and other healthcare workers and their students how to manage tracheostomy emergencies in children., conditionsModule conditions: Educational Study, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 69, type: ESTIMATED, armsInterventionsModule interventions name: Virtual reality (VR) tracheostomy educational tool, outcomesModule primaryOutcomes measure: Performance in simulation (time to key specific intervention, time to completion of scenario, and number of correct interventions completed), secondaryOutcomes measure: Knowledge using a bespoke knowledge multiple choice questionnaire adapted from a validated question bank., secondaryOutcomes measure: Participant satisfaction measured using a bespoke data collection tool., secondaryOutcomes measure: Virtual Reality Sickness, secondaryOutcomes measure: Usability using the validated system usability scale, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 68 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Manchester, city: Manchester, state: Greater Manchester, zip: M13 9PL, country: United Kingdom, contacts name: Jonathan R Abbas, MBChB, role: CONTACT, email: jonathan.abbas@postgrad.manchester.ac.uk, geoPoint lat: 53.48095, lon: -2.23743, hasResults: False
protocolSection identificationModule nctId: NCT06350682, orgStudyIdInfo id: HP-00107323, briefTitle: Resilient HIV Implementation Science With SGM Youths Using Evidence, acronym: RISE, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2027-09, completionDateStruct date: 2028-06, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: University of Maryland, Baltimore, class: OTHER, collaborators name: University of Florida, descriptionModule briefSummary: The Resilient HIV Implementation Science with SGM Youths using Evidence (RISE) Clinical Research Center will use a Type 2 hybrid-effectiveness-implementation study to evaluate the effectiveness and implementation of HMP, a youth-tailored digital health platform. It is hypothesized that SGM youths in the HMP intervention group will demonstrate improved PrEP initiation and viral load suppression over 12 months compared to the delayed HMP group., conditionsModule conditions: Hiv, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: SINGLE_GROUP, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 1500, type: ESTIMATED, armsInterventionsModule interventions name: HealthMPowerment (HMP), outcomesModule primaryOutcomes measure: PrEP initiation for HIV seronegative seropositive, primaryOutcomes measure: Viral load suppression for HIV, primaryOutcomes measure: RE-AIM, secondaryOutcomes measure: HIV testing cascade, secondaryOutcomes measure: PrEP continuum, secondaryOutcomes measure: HIV care and treatment continuum, secondaryOutcomes measure: Implementation effectiveness, eligibilityModule sex: MALE, minimumAge: 15 Years, maximumAge: 24 Years, stdAges: CHILD, stdAges: ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06350669, orgStudyIdInfo id: 9576-22-SMC, briefTitle: App-supported Vestibular Rehabilitation (RCT), statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2025-12, completionDateStruct date: 2026-03, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: University of Haifa, class: OTHER, collaborators name: Sheba Medical Center, collaborators name: Ben-Gurion University of the Negev, descriptionModule briefSummary: A randomized controlled trial to assess the efficacy of an app-assisted vestibular rehabilitation in increasing adherence to VR and treatment outcomes, conditionsModule conditions: Vestibular Disorder, conditions: Vestibular Diseases, conditions: Vestibular Abnormality, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The patients will be randomly assigned to either the intervention group (app-assisted vestibular rehabilitation) or the control group ("standard" vestibular rehabilitation/no app), primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 24, type: ESTIMATED, armsInterventionsModule interventions name: Vestibular rehabilitation phone application, outcomesModule primaryOutcomes measure: Adherence measures, primaryOutcomes measure: Timed up and go (TUG), secondaryOutcomes measure: Demographics and medical history intake, secondaryOutcomes measure: Vestibular functions- physical examination, secondaryOutcomes measure: Oculomotor functions- physical examination, secondaryOutcomes measure: Visual Analogue Scale (VAS), secondaryOutcomes measure: Dizziness Handicap Inventory (DHI), secondaryOutcomes measure: Activities-specific Balance Confidence Scale (ABC), secondaryOutcomes measure: Dynamic Gait Index (DGI), secondaryOutcomes measure: 10-Meters Walk Test (10MWT), secondaryOutcomes measure: 2-Minute Walk Test (2MWT), secondaryOutcomes measure: Dynamic Visual Acuity (DVA), secondaryOutcomes measure: Video Head Impulse Test (vHIT), secondaryOutcomes measure: Suppression Head Impulse Test (SHIMP), secondaryOutcomes measure: Exercise difficulty levels and symptoms severity, secondaryOutcomes measure: Cognitive reserve index questionnaire (CRIQ), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Sheba Medical Center, city: Ramat Gan, country: Israel, contacts name: Yoav Gimmon, PT, Ph.D, role: CONTACT, email: yoavgimmon@gmail.com, contacts name: Amit Wolfovitz, M.D, role: PRINCIPAL_INVESTIGATOR, contacts name: Shelly Levy-Tzedek, PhD, role: PRINCIPAL_INVESTIGATOR, contacts name: Liran Kalderon, M.Sc.PT, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 32.08227, lon: 34.81065, hasResults: False
protocolSection identificationModule nctId: NCT06350604, orgStudyIdInfo id: PRO-2023-355, briefTitle: Project WHADE: A Partner-Based Physical Activity Program for Women, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-02, primaryCompletionDateStruct date: 2024-06, completionDateStruct date: 2024-07, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Rowan University, class: OTHER, descriptionModule briefSummary: This study is designed to test the feasibility and acceptability of a new method for supporting physical activity among women ages 40-65 who have risk factors for cardiovascular disease. Each participant receives a trained physical activity coach and a physical activity partner; the partner is another woman in the program. Partners communicate with each other between weekly coaching sessions to provide support for physical activity behavior change., conditionsModule conditions: Hypertension, conditions: Type 2 Diabetes, conditions: Metabolic Syndrome, conditions: Smoking, conditions: High Cholesterol, conditions: PreDiabetes, conditions: Prehypertension, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: All participants receive the same intervention, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Project WHADE: A Partner-Based Physical Activity Program for Women, outcomesModule primaryOutcomes measure: Frequency of partner communication, primaryOutcomes measure: Satisfaction with partner communication, secondaryOutcomes measure: Physical activity behavior - steps, secondaryOutcomes measure: Physical activity behavior - active minutes, eligibilityModule sex: FEMALE, minimumAge: 40 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Rowan University, status: RECRUITING, city: Glassboro, state: New Jersey, zip: 08028, country: United States, contacts name: Sofia Gular, B.A., role: CONTACT, phone: 856-256-4872, email: projectwhade@rowan.edu, contacts name: Danielle Arigo, Ph.D., role: CONTACT, phone: 8562564500, phoneExt: 53775, email: arigo@rowan.edu, geoPoint lat: 39.70289, lon: -75.11184, hasResults: False
protocolSection identificationModule nctId: NCT06350591, orgStudyIdInfo id: 6038674, briefTitle: Evaluating Changes in Skeletal Muscle Proteins Following Resistance Exercise and Single-Leg Disuse, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-08, completionDateStruct date: 2024-08, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Queen's University, class: OTHER, descriptionModule briefSummary: Skeletal muscle plays a critical role in supporting human health. Beyond its role in providing the force to move, skeletal muscle accounts for a large proportion of metabolic rate, glucose disposal, and amino acid storage. Skeletal muscle is dynamically regulated by environmental stimuli, such as loading (i.e., resistance training\]) and unloading (i.e., disuse atrophy) as well as the intake of essential amino acids (EAAs). However, the precise mechanisms that regulate skeletal muscle mass in response to various conditions (e.g., EAA supplementation, resistance training, and unloading) are not completely understood. Therefore, concerted efforts to better understand the mechanisms regulating skeletal muscle size are needed that aid in the development of therapeutic interventions to combat age, disease, and disuse related muscular atrophy., conditionsModule conditions: Healthy, conditions: Skeletal Muscle Atrophy, conditions: Skeletal Muscle Hypertrophy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: parallel, within-subject design, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 14, type: ESTIMATED, armsInterventionsModule interventions name: Immobilization, interventions name: Resistance training, outcomesModule primaryOutcomes measure: Changes in average rates of muscle synthesis, primaryOutcomes measure: Dynamic proteomic profiling, secondaryOutcomes measure: Protein expression (phosphorylation and content) of novel and known targets implicated in protein translation and mitochondrial-related protein expression, secondaryOutcomes measure: Muscle torque, secondaryOutcomes measure: Quadriceps skeletal muscle volume, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 30 Years, stdAges: ADULT, contactsLocationsModule locations facility: School of Kinesiology and Health Studies, status: RECRUITING, city: Kingston, state: Ontario, zip: K7L 3N6, country: Canada, contacts name: Chris McGlory, PhD, role: CONTACT, phone: 6135336000, phoneExt: 75410, email: chris.mcglory@queensu.ca, contacts name: Kristine Boileau, BSc, role: CONTACT, email: 22kb15@queensu.ca, contacts name: Chris McGlory, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 44.22976, lon: -76.48101, hasResults: False
protocolSection identificationModule nctId: NCT06350578, orgStudyIdInfo id: BUHOOTH-D-23-00073, briefTitle: A Randomized Clinical Trial Comparing Hall vs. Conventional Technique in Primary Molars., statusModule overallStatus: RECRUITING, startDateStruct date: 2023-12-06, primaryCompletionDateStruct date: 2025-03, completionDateStruct date: 2025-06, studyFirstPostDateStruct date: 2024-04-05, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Primary Health Care Corporation, Qatar, class: OTHER_GOV, descriptionModule briefSummary: This study aims to assess the comparative effectiveness of the Hall technique (HT) and the conventional technique (CT) for placing Stainless Steel Crowns (SSCs) in primary molars with approximal caries., conditionsModule conditions: Dental Caries, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: A binary outcome non-inferiority randomized trial., primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: Single-blind, whoMasked: CARE_PROVIDER, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Hall Crown Technique, interventions name: Conventional SSC Technique, outcomesModule primaryOutcomes measure: Restoration survival at 12 months, primaryOutcomes measure: Occlusal vertical dimension (OVD) resolution, primaryOutcomes measure: Tooth survival, primaryOutcomes measure: Procedural time, secondaryOutcomes measure: Participant's cooperation, secondaryOutcomes measure: Participant's pain perception, secondaryOutcomes measure: Treatment perceptions and opinions of the parents, eligibilityModule sex: ALL, minimumAge: 3 Years, maximumAge: 9 Years, stdAges: CHILD, contactsLocationsModule locations facility: Primary Healthcare Corporation, status: RECRUITING, city: Doha, country: Qatar, contacts name: Research Section, role: CONTACT, phone: +97444069917, email: researchsection@phcc.gov.qa, geoPoint lat: 25.28545, lon: 51.53096, hasResults: False