protocolSection identificationModule nctId: NCT06309433, orgStudyIdInfo id: DXA-TKA, briefTitle: Assessment of Periprosthetic Bone Mineral Density in Patients Undergoing Total Knee Prosthesis of Different Design, acronym: DXA-TKA, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-08-30, primaryCompletionDateStruct date: 2027-12, completionDateStruct date: 2028-04, studyFirstPostDateStruct date: 2024-03-13, lastUpdatePostDateStruct date: 2024-03-13, sponsorCollaboratorsModule leadSponsor name: Istituto Ortopedico Rizzoli, class: OTHER, descriptionModule briefSummary: compare changes in BMD via DXA at the level of the femoral and tibial periprosthetic bone between two groups of patients undergoing cemented TKA of different design (posterior stabilization vs posterior cruciate preservation) with proms at a 2-year follow-up., conditionsModule conditions: Periprosthetic Osteolysis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: dual energy x-ray absorptiometry, outcomesModule primaryOutcomes measure: Periprosthetic bone mineral density measurement, primaryOutcomes measure: Periprosthetic bone mineral density measurement, primaryOutcomes measure: Periprosthetic bone mineral density measurement, primaryOutcomes measure: Periprosthetic bone mineral density measurement, secondaryOutcomes measure: Knee Society Score, secondaryOutcomes measure: Knee Society Score, secondaryOutcomes measure: Knee Society Score, secondaryOutcomes measure: Knee Society Score, secondaryOutcomes measure: Western Ontario and McMaster Universities Arthritis Index, secondaryOutcomes measure: Western Ontario and McMaster Universities Arthritis Index, secondaryOutcomes measure: Western Ontario and McMaster Universities Arthritis Index, secondaryOutcomes measure: Western Ontario and McMaster Universities Arthritis Index, secondaryOutcomes measure: Knee injury and Osteoarthritis Outcome Score, secondaryOutcomes measure: Knee injury and Osteoarthritis Outcome Score, secondaryOutcomes measure: Knee injury and Osteoarthritis Outcome Score, secondaryOutcomes measure: Knee injury and Osteoarthritis Outcome Score, secondaryOutcomes measure: 36-Item Short Form Health Survey, secondaryOutcomes measure: 36-Item Short Form Health Survey, secondaryOutcomes measure: 36-Item Short Form Health Survey, secondaryOutcomes measure: 36-Item Short Form Health Survey, eligibilityModule sex: ALL, minimumAge: 45 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Stefano Zaffagnini, status: RECRUITING, city: Bologna, state: Italia, country: Italy, contacts name: Stefano Zaffagnini, MD, role: CONTACT, phone: 051 6366075, email: stefano.zaffagnini@unibo.it, geoPoint lat: 44.49381, lon: 11.33875, locations facility: Istituto ortoepdico rizzoli, status: RECRUITING, city: Bologna, zip: 40136, country: Italy, contacts name: Stefano Zaffagnini, Prof., role: CONTACT, phone: 00390516366111, email: stefano.zaffagnini@unibo.it, geoPoint lat: 44.49381, lon: 11.33875, hasResults: False