hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06288139, orgStudyIdInfo id: open fracture tibia, briefTitle: Management of Open Fracture Tibia in Teenagers, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2025-01-01, completionDateStruct date: 2025-02-01, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: The aim of this study is to study the incidence of open tibial fractures in early teenagers and evaluate the management outcomes, conditionsModule conditions: Open tíbia Fracture, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, outcomesModule primaryOutcomes measure: Number, secondaryOutcomes measure: To evaluate treatment outcomes, secondaryOutcomes measure: Soft tissue healing, secondaryOutcomes measure: Complication, eligibilityModule sex: ALL, minimumAge: 10 Years, maximumAge: 19 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06288126, orgStudyIdInfo id: MoMM-FET, briefTitle: Maternal and Fetal Metabolic Changes, acronym: MoMM-FET, statusModule overallStatus: COMPLETED, startDateStruct date: 2019-08-01, primaryCompletionDateStruct date: 2020-10-09, completionDateStruct date: 2021-01-18, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Azienda Ospedaliero, Universitaria Pisana, class: OTHER, descriptionModule briefSummary: The goal of this observational prospective project is to study the metabolic alterations during normal and complicated pregnancies, obtaining an early detection of metabolic changes, offering new insights into future prevention and treatment strategies for both mother and offspring.Primary objectives:* measurement of maternal blood adipokine levels, during the first trimester of pregnancy, in two groups of women (high and low risk), in order to identify early markers which, in conjunction with the medical history, can identify women at increased risk of developing GDM* ultrasound measurement of adipose tissue deposits at ectopic sites, comparing low- and high-risk women, and assessing the effect of pregnancy on these deposits.* Identification, by targeted ultrasound assessment, of fetuses at increased risk of macrosomia.Secondary objectives:* Evaluation of the prevalence of GDM and its complications in a population of low- and high-risk women.* Evaluation of neonatal complications in children born to low- and high-risk mothers (need for resuscitation, hypoglycaemia, hypocalcaemia, admission to neonatal intensive care unit).The participants will be recruited during first trimester ultrasound after signing the informed consent., conditionsModule conditions: Pregnancy Related, conditions: Maternal-Fetal Relations, conditions: Metabolism Disorder, Glucose, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 457, type: ACTUAL, armsInterventionsModule, outcomesModule primaryOutcomes measure: Blood adipokine levels, primaryOutcomes measure: Abdominal Fat Thickness, primaryOutcomes measure: Fetal Adipose Tissue Deposits, secondaryOutcomes measure: Gestational diabetes prevalence, secondaryOutcomes measure: Obstetric complications and mode of delivery, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Azienda Ospedaliera Universitaria Pisana, city: Pisa, zip: 56126, country: Italy, geoPoint lat: 43.70853, lon: 10.4036, hasResults: False
protocolSection identificationModule nctId: NCT06288100, orgStudyIdInfo id: OWHTOPTS, briefTitle: The Effect of Open Wedge High Tibial Osteotomy on the Posterior Tibial Slope In Skeletally Mature Patient, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-01-01, primaryCompletionDateStruct date: 2023-12-31, completionDateStruct date: 2024-01-01, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Al-Azhar University, class: OTHER, descriptionModule briefSummary: High tibial osteotomy has been established as an efficient surgical intervention for young patients with uni-compartmental osteoarthritis of the knee. The principle of this surgery involves the realignment of the lower extremity to shift the load distribution from the medial compartment into the lateral compartment, thus leading to a decrease in symptoms related to medial compartment knee Osteoarthritis However, medial opening wedge high tibial osteotomy is also known to affect the posterior tibial slope angle, and it is reported that posterior tibial slope angle increases after medial opening wedge high tibial osteotomy ., conditionsModule conditions: Genu Varum, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 40, type: ACTUAL, armsInterventionsModule interventions name: Observation, outcomesModule primaryOutcomes measure: The Effect of Open Wedge High Tibial Osteotomy on the Posterior Tibial Slope In Skeletally Mature Patient, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Mohamed Abdelfattah Abbas, city: Assiut, country: Egypt, geoPoint lat: 27.18096, lon: 31.18368, hasResults: False
protocolSection identificationModule nctId: NCT06288074, orgStudyIdInfo id: SF-2022-1-1061, briefTitle: Diagnosis and Treatment Strategy Optimization of Severe Pneumonia Based on Multi-omics Data Integration, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-10, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Capital Medical University, class: OTHER, descriptionModule briefSummary: Severe community-acquired pneumonia still has a high incidence and mortality, but the molecular mechanism and prognostic biomarkers of severe community-acquired pneumonia caused by different pathogens are still unclear, and the best treatment strategy has not been determined. Based on this, this project intends to take patients with severe community-acquired pneumonia caused by different pathogens as the research object, explore the molecular mechanism of severe community-acquired pneumonia from multiple angles, integrate relevant research data to evaluate the rationality of initial empirical medication, and lay the foundation for precise treatment of severe pneumonia. The research results will help to develop a new rapid and accurate target for clinical diagnosis and efficacy evaluation of severe pneumonia, and build a precise treatment system for severe pneumonia., conditionsModule conditions: Severe Community-acquired Pneumonia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 300, type: ESTIMATED, armsInterventionsModule interventions name: Multi-omics tests, outcomesModule primaryOutcomes measure: Hospital mortality, secondaryOutcomes measure: Cause of death, secondaryOutcomes measure: Length of stay, secondaryOutcomes measure: Length of ICU stay, secondaryOutcomes measure: Expense during hospitalization, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Beijing Institute of Respiratory Medicine, status: RECRUITING, city: Beijing, state: Beijing, zip: 100027, country: China, contacts name: Zhaohui Tong, Dr, role: CONTACT, phone: +86 010 8523 1000, email: 13910930309@163.com, geoPoint lat: 39.9075, lon: 116.39723, hasResults: False
protocolSection identificationModule nctId: NCT06288048, orgStudyIdInfo id: 23/107-EC X TFM 07/03/2023, briefTitle: Effect of Mirror Therapy on Post-Needling Pain Following Deep Dry Needling of Myofascial Trigger Point in Lateral Elbow Pain, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-04-01, primaryCompletionDateStruct date: 2024-03-07, completionDateStruct date: 2024-06-30, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Universidad Europea de Canarias, class: OTHER, descriptionModule briefSummary: The goal of this randomized, controlled pilot trial is to investigate the immediate effects of incorporating Mirror Visual Feedback Therapy (MFT) on pain sensitivity and motor performance in individuals experiencing Post-needling pain associated with lateral elbow pain. The main questions it aims to answer are:* Does incorporating Mirror Visual Feedback Therapy reduce Post-needling pain intensity?* Does incorporating Mirror Visual Feedback Therapy improve pressure pain threshold?* Does incorporating Mirror Visual Feedback Therapy improve maximum grip strenght?Participants will be asked to undergo pre- and post-treatment evaluations, which include assessments of Post-needling pain intensity, pressure pain threshold, two-point discrimination threshold, and maximum hand grip strength.Participants in the Experimental Group will receive Deep Dry Needling in the m. Brachioradialis, Ischemic Compression, Cold Spray, Stretching, and Mirror Visual Feedback Therapy. Those in the Control Group will not receive Mirror Visual Feedback Therapy.Researchers will compare the Experimental Group to the Control Group to see if the incorporation of Mirror Visual Feedback Therapy results in a reduction in Post-needling pain intensity and improvement in pressure pain threshold., conditionsModule conditions: Lateral Elbow Pain, designModule studyType: INTERVENTIONAL, phases: PHASE2, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: Allocation and data assessor were blinded., whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 49, type: ESTIMATED, armsInterventionsModule interventions name: Experimental: Deep Dry Needling (DDN), Ischemic Compression, Cold Spray with Stretching + MFT, interventions name: Deep Dry Needling (DDN), Ischemic Compression, Cold Spray with Stretching, outcomesModule primaryOutcomes measure: Pain Intensity, primaryOutcomes measure: Pain pressure threshold, primaryOutcomes measure: Two-point discrimination threshold, primaryOutcomes measure: Maximum hand grip strength, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Universidad Europea de Canarias, city: La Orotava, state: Santa Cruz De Tenerife, zip: 38300, country: Spain, geoPoint lat: 28.39076, lon: -16.52309, hasResults: False
protocolSection identificationModule nctId: NCT06288035, orgStudyIdInfo id: R.21.02.1191, briefTitle: Oral Dexamethasone for Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-04, primaryCompletionDateStruct date: 2025-03, completionDateStruct date: 2025-03, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Mansoura University, class: OTHER, descriptionModule briefSummary: Postoperative nausea and vomiting (PONV) are common complications after laparoscopic cholecystectomy. This study aims to evaluate the efficacy of the administration of prophylactic oral dexamethasone at night before surgery in preventing PONV after elective laparoscopic cholecystectomy., conditionsModule conditions: Postoperative Nausea and Vomiting, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: This is a parallel, two-arm, randomized (1:1), controlled, single-center non-inferiority trial. Adults (≥18 years) with ASA physical status I-III scheduled for elective laparoscopic cholecystectomy will be eligible for inclusion. The participants will be randomized to receive either 8 mg of IV Dexamethasone at the time of induction of anesthesia or 8 mg of oral Dexamethasone at night before surgery. The primary outcome will be the incidence of postoperative nausea and vomiting. 814 patients are intended to be recruited for this non-inferiority trial., primaryPurpose: PREVENTION, maskingInfo masking: SINGLE, maskingDescription: The outcome assessors will be blinded to the group allocation., whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 814, type: ESTIMATED, armsInterventionsModule interventions name: Dexamethasone Oral, interventions name: Dexamethasone, outcomesModule primaryOutcomes measure: Postoperative nausea or vomiting (PONV), secondaryOutcomes measure: Rescue antiemetic, secondaryOutcomes measure: Early PONV, secondaryOutcomes measure: Late PONV, secondaryOutcomes measure: Visual Analogue Scale (VAS) at the time of discharge from PACU, secondaryOutcomes measure: VAS at the time of discharge from hospital, secondaryOutcomes measure: Postoperative fatigue, secondaryOutcomes measure: Postoperative quality of recovery, secondaryOutcomes measure: Post-Discharge Nausea and Vomiting (PDNV), otherOutcomes measure: Surgical Site Infection (at follow-up), otherOutcomes measure: Itching or burning sensation on dexamethasone injections, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Mansoura University Faculty of Medicine, status: RECRUITING, city: Mansoura, state: Aldakahlia, zip: 35516, country: Egypt, contacts name: Moataz M Emara, MD, EDAIC, role: CONTACT, phone: 01064048848, email: mm.emara@mans.edu.eg, geoPoint lat: 31.03637, lon: 31.38069, hasResults: False
protocolSection identificationModule nctId: NCT06288022, orgStudyIdInfo id: COA. MURA2023/947, briefTitle: Comparison of Total Tubeless Mini-PCNL Versus Tubeless Mini-PCNL, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2026-04-30, completionDateStruct date: 2026-06-30, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-07, sponsorCollaboratorsModule leadSponsor name: Mahidol University, class: OTHER, descriptionModule briefSummary: Limited literature has focused on the use of totally tubeless mini-percutaneous nephrolithotomy (Mini-PCNL) for the treatment of large renal stones.This Randomized Controlled trial aims to compare complication and safety of Mini-PCNL between total tubeless and tubeless Mini-PCNL., conditionsModule conditions: Surgery-Complications, conditions: Nephrolithiasis Staghorn Calculus, conditions: Safety Issues, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized Controlled Trial in 2 group1. total tubeless mini-PCNL2. tubeless mini-PCNL, primaryPurpose: OTHER, maskingInfo masking: DOUBLE, maskingDescription: All eligible patients will be provided with an explanation of the research and invited to participate.Patient will participate or not depends on whether they not meet the surgical exclusion criteria. If they meet the criteria, they will not participate in the research. If they not meet the criteria, they will be randomly assigned to one of the groups.Patients will not be informed of the treatment intervention in advance, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, enrollmentInfo count: 130, type: ESTIMATED, armsInterventionsModule interventions name: total tubeless mini-PCNL, interventions name: tubeless mini-PCNL, outcomesModule primaryOutcomes measure: incidence of complications between total tubeless mini-pcnl and tubeless mini-PCNL, secondaryOutcomes measure: The secondary objective is to assess the surgical outcomes between total tubeless mini-pcnl and tubeless mini-PCNL, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ramathibodi Hospital, Mahidol University, city: Bangkok, state: Ratchathewi, zip: 10400, country: Thailand, contacts name: Thanakorn Sirajarus, role: CONTACT, phone: 086-599-3259, email: Thanakorn.sjr@gmail.com, contacts name: Chinnakhet Ketsuwan, role: CONTACT, phone: 086-345-6901, email: chinnakhet.ket@mahidol.ac.th, geoPoint lat: 13.75398, lon: 100.50144, hasResults: False
protocolSection identificationModule nctId: NCT06288009, orgStudyIdInfo id: 2135389, briefTitle: Outcomes of Running Locking Suture vs Standard Running Suture in Surgical Wounds, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2025-03-01, completionDateStruct date: 2025-06-01, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: University of California, Davis, class: OTHER, descriptionModule briefSummary: When patients have surgery on the head and face, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring. Several studies have been done to test ways to close wounds that reduce scarring. The most commonly performed closure technique uses running sutures, where a single strand of suture is continued along the length of the wound with a series of uninterrupted stiches. However, alternative closure techniques exist such as the running locking suture, which can offer advantages such as improved tension and thus reduce post-operative complications with better aesthetic outcome. In this study, half the wound will be stitched with standard running sutures and the other half will be stitched with running locking sutures. This will allow us to see if the side with running locking sutures heals with less scarring., conditionsModule conditions: Scarring, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: SINGLE, maskingDescription: Two blinded observers will record their scores independently using the POSAS instrument., whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Running locking suture, interventions name: Standard running suture, outcomesModule primaryOutcomes measure: Observer Scar Assessment as measured by Patient Observer Scar Assessment Score (POSAS), secondaryOutcomes measure: Patient Scar Assessment as measured by Patient Observer Scar Assessment Score (POSAS), secondaryOutcomes measure: Width of Scar as measured using Trace-to-Tape Method, secondaryOutcomes measure: Complications or Adverse Events from Treatment, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of California, Davis - Dermatology Department, status: RECRUITING, city: Sacramento, state: California, zip: 95816, country: United States, contacts name: John Robb, BS, role: CONTACT, phone: 916-551-2636, email: jmrobb@ucdavis.edu, contacts name: Daniel Eisen, MD, role: CONTACT, phone: 916-551-2611, email: dbeisen@ucdavis.edu, contacts name: Daniel Eisen, MD, role: PRINCIPAL_INVESTIGATOR, contacts name: Keemberly Kim, MD, role: SUB_INVESTIGATOR, contacts name: Samantha Daniel, MD, role: SUB_INVESTIGATOR, geoPoint lat: 38.58157, lon: -121.4944, hasResults: False
protocolSection identificationModule nctId: NCT06287996, orgStudyIdInfo id: 23MMHIS503e NA, briefTitle: Effects of Warm Water Footbath Intervention on Sleep Quality, Fatigue and Heart Rate Variability in Patients With Heart Failure, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2024-02-23, primaryCompletionDateStruct date: 2024-06-01, completionDateStruct date: 2024-08-01, studyFirstPostDateStruct date: 2024-03-01, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Mackay Memorial Hospital, class: OTHER, descriptionModule briefSummary: This study adopted an experimental research design to explore the effects of a warm water foot bath program on fatigue, sleep, and heart rate variability in patients with heart failure. The subjects of the study were heart failure patients in the cardiology outpatient department. The patients were randomly assigned to the experimental group and the control group. The control group received routine care and wore an actigraph. The experimental group received 4 additional care in addition to routine care and wearing an actigraph. Weekly warm water foot bath, data collection includes subjective sleep quality and fatigue level, physiological measurements: sleep quality-sleep time and efficiency, and heart rate variability index., conditionsModule conditions: Footbath, conditions: Heart Failure, conditions: Sleep Quality, conditions: Fatigue, conditions: Heart Rate Variability, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 76, type: ESTIMATED, armsInterventionsModule interventions name: footbath and actigraphy, interventions name: actigraphy, outcomesModule primaryOutcomes measure: sleep quality, secondaryOutcomes measure: fatigue, otherOutcomes measure: heart rate variability, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Mackay Memorial Hospital, city: Taipei, state: Zhongshan, zip: 104, country: Taiwan, geoPoint lat: 25.04776, lon: 121.53185, hasResults: False