protocolSection identificationModule nctId: NCT06298227, orgStudyIdInfo id: Medipol Hospital 1, briefTitle: Erector Spinae Plane Block vs Quadratus Lumborum Block for Laparoscopic Nephrectomy, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-11, primaryCompletionDateStruct date: 2024-07-20, completionDateStruct date: 2024-07-30, studyFirstPostDateStruct date: 2024-03-07, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: Istanbul Medipol University Hospital, class: OTHER, descriptionModule briefSummary: Ultrasound (US) guided Quadratus Lumborum Block (QLB) is performed at the level of the 12th rib, in the parasagittal oblique plane, at the L1-L2 level. As there are modifications of the block generally local anesthetic is given between quadratus lumborum (QL) and psoas major (PM) muscles (Anterior QLB). The QLB provides a sensory block between T7 - L1. Therefore, QLBs are used to provide postoperative analgesia for abdominal, obstetric, gynecologic, and urologic surgeries.US-guided erector spinae plane block (ESPB) is performed at the level of the T11 transverse process. After visualization of the erector spinae (ES) muscle and the transverse process, local anesthetic is injected under the ES muscle. ESPB provides a sensory block of the anterior, posterior, and lateral thoracic and abdominal walls accordingly it's used for postoperative analgesia after thoracal wall repairs, thoracotomies, percutaneous nephrolithotomies, nephrectomies, and ventral hernia repairs.This study aims to compare the effectiveness of US-guided ESPB and QLB on postoperative pain control after laparoscopic nephrectomy., conditionsModule conditions: Kidney Diseases, conditions: Kidney Failure, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Sixty patients aged 18-65 years old with American Society of Anesthesiologists (ASA) classification I-II and scheduled for laparoscopic nephrectomy surgery will be included in the study. Patients will be randomly divided into two groups (Group ESPB = ESPB group, Group QLB = QLB group) including 30 patients each, before entering the operating room., primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: Outcomes assessor and participants will be blinded to the study, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Postoperative analgesia management with Paracerol® and IV PCA with Talinat®, interventions name: Erector spinae plane block, interventions name: Quadratus lumborum plane block, outcomesModule primaryOutcomes measure: Amount of total opioid consumption (Fentanyl PCA) at the first 24 hours period postoperatively, secondaryOutcomes measure: Pain scores (Numerical rating scale-NRS), secondaryOutcomes measure: Need for rescue analgesia (meperidine), secondaryOutcomes measure: Adverse events, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Istanbul Medipol University Mega Hospital Complex, status: RECRUITING, city: Istanbul, state: Bağcılar, country: Turkey, contacts name: Ayşe İnce, Assist Prof, role: CONTACT, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False