protocolSection identificationModule nctId: NCT06295016, orgStudyIdInfo id: NYCU112130AE, briefTitle: Stressors and Recovery Regulation on the Super-compensation Effect, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-09-01, primaryCompletionDateStruct date: 2024-08-31, completionDateStruct date: 2025-08-31, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: National Yang Ming University, class: OTHER, descriptionModule briefSummary: Purpose: Investigating the effects of stressors and recovery regulation on the super-compensation effect of high-intensity intensive training (IT) in endurance athletes. Methods: This study will recruit 176 competitively trained endurance adult athletes. Participants will conduct a 7-week 3-stage experiment, including 3 weeks of regular training, 3 weeks of 130% progressive IT, and 1 week of 55% taper. Measurement will include training responses (performance and fatigue symptoms), stressors, recovery regulation, and mood state at baseline, during and after regular training, IT, and taper separately. According to the performance after taper, all participants will category into either the responder or non-responder of well-response to supercompensation effect. Statistic analysis: Independent t-test, Chi-squared test, and binary logistic regression will be used to compare the difference in training responses, stressors, recovery regulation, and mood state characteristics between responder and non-responder groups. P value sets at 0.15 for identifying the potential predictors. Logistic stepwise multiple regression will be used further to determine the significant predictors for the responders of well-response to the super-compensation among endurance athletes. P value sets at 0.05., conditionsModule conditions: Exercise Overtraining, conditions: Stressor, Psychological, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: SINGLE_GROUP, interventionModelDescription: The present study is designed as a prospective intervention and prognostic prediction study, employing a single-subject design with a reversal (ABA) design. This design involves a self-controlled intervention experiment with three phases: baseline training period (A), high-intensity, high-volume training period (B), and reduced training period (A). Subsequently, the study aims to explore predictive factors influencing the presence or absence of favorable compensatory training effects following the intervention., primaryPurpose: SCREENING, maskingInfo masking: DOUBLE, maskingDescription: Prior to the commencement of the experiment and during the experimental period, both the participants and the investigator will be unaware of whether the participants exhibit a good response to compensatory training effects. After the participants complete the entire experimental procedure, they will be grouped post hoc based on their outcomes following the intervention, according to predetermined criteria.The criteria for determining whether there is a good response to compensatory training effects:1. Non-response group: Exercise performance during the tapering period (week 7) shows a significant increase compared to post-intervention (week 6) and is higher than pre-intervention (week 3) exercise performance.2. Response group: Exercise performance during the tapering period (week 7) shows a significant increase compared to post-intervention (week 6) and is higher than the change in exercise performance during normal training (= week 3 - week 1)., whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 158, type: ESTIMATED, armsInterventionsModule interventions name: High-intensity intensive training, interventions name: Taper, outcomesModule primaryOutcomes measure: Stressor, primaryOutcomes measure: Recovery regulation, primaryOutcomes measure: Mood state, primaryOutcomes measure: Peak power output, secondaryOutcomes measure: Maximal heart rate, secondaryOutcomes measure: Fatigue state, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule locations facility: Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University, status: RECRUITING, city: Taipei, zip: 112304, country: Taiwan, contacts name: Wei-Wun Tsai, role: CONTACT, phone: +886-02-2826-7939, email: tmwk@nycu.edu.tw, geoPoint lat: 25.04776, lon: 121.53185, hasResults: False