hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06321874, orgStudyIdInfo id: EPHIRAS, briefTitle: Effects of Oxygen After Abdominal Oncological Surgery, acronym: EPHIRAS, statusModule overallStatus: COMPLETED, startDateStruct date: 2011-01-01, primaryCompletionDateStruct date: 2011-11-01, completionDateStruct date: 2011-11-01, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Jules Bordet Institute, class: OTHER, descriptionModule briefSummary: The aims of the research is to determine whether a Hyperoxic intermittent stimuli protocol can increase reticulocyte counts, signififying a rise in EPO production, in patients undergoing abdominal surgery, conditionsModule conditions: Abdominal Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomization was conducted post-surgery in a 1:1 ratio across groups: Normobaric Oxygen Paradox (NOP) group, and a control (CTR) group. The NOP group received 60% oxygen for two hours on days 1, 3, and 5 post-surgery using a venti-mask. The CTR group did not receive oxygen therapy during the post-operatory period starting from day 1. All patients could receive oxygen during the surgery and the first 24 hours post-surgery (day 0) as needed. The belonging to one group or the other was blinded to the laboratory staff., primaryPurpose: BASIC_SCIENCE, maskingInfo masking: SINGLE, maskingDescription: The belonging to one group or the other was blinded to the laboratory staff., whoMasked: CARE_PROVIDER, enrollmentInfo count: 49, type: ACTUAL, armsInterventionsModule interventions name: Oxygen, outcomesModule primaryOutcomes measure: Percentage change in reticulocyte count, secondaryOutcomes measure: haematocrit levels mesure, secondaryOutcomes measure: haemoglobin levels mesure, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Khalife Maher, city: Brussels, zip: 1000, country: Belgium, geoPoint lat: 50.85045, lon: 4.34878, hasResults: False
protocolSection identificationModule nctId: NCT06321848, orgStudyIdInfo id: DUCGM2426, briefTitle: Weaning Ventilator Using Heart, Lung And Diaphragm Ultrasound, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2026-03, completionDateStruct date: 2026-04, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: Hanoi Medical University, class: OTHER, descriptionModule briefSummary: Postextubation distress is detrimental to the prognosis of critically ill patients with successful spontaneous breathing trial. Failure to wean is known to be connected with heart, lung, and diaphragm problems. The aim of this study was to investigate how a composite model comprising diaphragm, lung, and heart ultrasonography indications could predict the weaning outcome.Methods: Ultrasonic features of the diaphragm, heart, and lungs are going to be collected along with clinical data about the patients. Either the successful weaning group or the failed weaning group is going to comprised the patients. Multivariate logistic regression analysis is going to be used to identify the variables that may be associated with the likelihood of weaning failure. A multiindicator combination model is going to be developed to increase the predictive accuracy after the possible indicators' accuracy in foretelling the weaning outcome was assessed., conditionsModule conditions: Ventilator Weaning, conditions: Ultrasound, designModule studyType: OBSERVATIONAL, designInfo observationalModel: ECOLOGIC_OR_COMMUNITY, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 190, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: The ventilator weaning outcome, secondaryOutcomes measure: The hospital length of stay, secondaryOutcomes measure: The ICU length of stay, secondaryOutcomes measure: The duration of mechanical ventilation, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06321835, orgStudyIdInfo id: 16-10/13, briefTitle: The Effect of Different Patient Positions on Endotracheal Tube Cuff Pressure, statusModule overallStatus: COMPLETED, startDateStruct date: 2016-12-09, primaryCompletionDateStruct date: 2018-01-15, completionDateStruct date: 2018-06-15, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: Ege University, class: OTHER, descriptionModule briefSummary: Background: The placement of a cuffed endotracheal tube for the administration of general anesthesia is a routine procedure. In the part of the intubation tube located in the trachea, there is a balloon (cuff) to prevent gase leakage, aspiration of secretions and gastric contents into the lungs. Inadequate inflation of cuff may lead to inadequate ventilation, aspiration and associated complications, while excessive inflation may cause complications in ranging from postoperative pharyngeal complaints to tracheal rupture due to increased cuff pressure. This study aimed to determine the effect of different patient positions on the endotracheal cuff pressure in patients undergoing urological procedures.Methods: This is a prospective study conducted on 200 patients undergoing urological procedures in supine, prone, lateral flank and litotomy positions. After intubation (T0), the cuff pressure was checked with a cuff manometer and adjusted at 25 cmH2O as the baseline and continuously monitored. The cuff pressure was checked again before (T1) and after achieving the final position (T2) and then at 5 (T3), 10 (T4), 15 (T5), 30, 45, 60, 90, 120, 150, 180 minutes after the position, at the end of the procedure (T6) and before extubation (T7). At postoperative 2nd and 12th hours, the patients were interviewed for sore throat, hoarseness and cough., conditionsModule conditions: Endotracheal Tube Cuff Pressure, conditions: Patient Positions, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 200, type: ACTUAL, armsInterventionsModule interventions name: Endotracheal tube cuff pressure measurement, outcomesModule primaryOutcomes measure: The Effect of Different Patient Positions on Endotracheal Tube Cuff Pressure in Patients Undergoing Urological Procedures: A Prospective Study, secondaryOutcomes measure: The Effect of Different Patient Positions on Endotracheal Tube Cuff Pressure in Patients, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06321809, orgStudyIdInfo id: HUTF-FM-DABDCO-01, briefTitle: Intensive Lifestyle Interventions to Overweight and Obese Patients in Primary Care, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-01-25, primaryCompletionDateStruct date: 2022-10-01, completionDateStruct date: 2022-12-01, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-21, sponsorCollaboratorsModule leadSponsor name: Duygu Ayhan Baser, class: OTHER, collaborators name: Hacettepe University, descriptionModule briefSummary: The goal of this clinical trial is to compare in the effect of different lifestyle interventions in overweight and obese participants. The main questions it aims to answer are:* effect on anthropometric measurements* effect on lipid profile* effect on weight-related quality of life* observe the differences between interventions The study participants were stratified into three groups: intervention, control-1, and control-2.* Intervention group: They were given a calorie-restricted diet and exercise plan by a dietician or physiotherapist at their first visit, and were followed up by telephone calls at weeks 2, 4, 6, 8 and 10 over 12 weeks.* Control-1 group: During the initial medical interview, the participants were given a calorie-restricted diet programme by a dietician and an exercise programme by a physiotherapist; they were followed up over 12 weeks with telephone calls at week 4.* Control-2 group: The participants were not provided with any programme, and the importance of weight loss was emphasised by the family physicians. Dietary and physical activity advice was given according to the recommendations in the Turkish Endocrine and Metabolism Association 2019 Obesity Diagnosis and Treatment Guide, and was followed up with phone calls at weeks 2, 4, 6, 8 and 10 over a 12-weeks., conditionsModule conditions: Obesity, conditions: Life Style, conditions: Lifestyle, Sedentary, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CROSSOVER, timePerspective: PROSPECTIVE, enrollmentInfo count: 152, type: ACTUAL, armsInterventionsModule interventions name: intensive lifestyle, outcomesModule primaryOutcomes measure: primary outcome, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Hacettepe University, city: Ankara, country: Turkey, geoPoint lat: 39.91987, lon: 32.85427, hasResults: False
protocolSection identificationModule nctId: NCT06321783, orgStudyIdInfo id: E-77082166-604.01.02-407303, briefTitle: Relationship Between Cervical Proprioception and Endurance With Hand-eye Coordination and Postural Control, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-03-06, primaryCompletionDateStruct date: 2024-07-12, completionDateStruct date: 2024-09-06, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: Gazi University, class: OTHER, descriptionModule briefSummary: The aim of our study is to investigate the relationship between cervical proprioception and cervical muscle endurance with hand-eye coordination and postural control in individuals with forward head posture (FHP) and to compare them with a control group with normal head posture. After the demographic information and physical characteristics of the individuals are recorded, their craniovertebral angles (CVA) will be measured and they will be assigned to Group 1 (forward head posture) or Group 2 (normal head posture). Then, the individuals' cervical proprioception, hand-eye coordination, postural control and cervical muscle endurance values will be measured respectively. Cervical muscle endurance will be evaluated last, taking into account possible muscle fatigue, in order not to affect other measurement results. The recorded values will be compared between groups and the relationship of cervical proprioception and muscle endurance with hand-eye coordination and postural control will be examined. All evaluations will be made by the same researcher., conditionsModule conditions: Forward Head Posture, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Assessment, outcomesModule primaryOutcomes measure: Cervical Proprioception, primaryOutcomes measure: Hand-Eye Coordination, primaryOutcomes measure: Postural Stability Test, primaryOutcomes measure: Stability Limit Test, primaryOutcomes measure: Modified Sensory Organization Test, primaryOutcomes measure: Endurance of Cervical Muscles, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 24 Years, stdAges: ADULT, contactsLocationsModule locations facility: Gazi University, status: RECRUITING, city: Ankara, state: Çankaya, zip: 06490, country: Turkey, contacts name: Tuğçe Çoban, MSc, role: CONTACT, phone: +905454098540, email: fzttugce@yahoo.com, geoPoint lat: 39.91987, lon: 32.85427, hasResults: False
protocolSection identificationModule nctId: NCT06321770, orgStudyIdInfo id: 075-2022, briefTitle: Oral Supplementation With Active Collagen Peptides and Skin Health Improvement, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-03-15, primaryCompletionDateStruct date: 2023-04-16, completionDateStruct date: 2023-05-24, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: Gala Servicios Clinicos S.L., class: OTHER, descriptionModule briefSummary: The present study aims to investigate the efficacy of daily supplementation with COLLinstant® LMW over a 6-week period in improving visible signs of aging. This in-cludes assessing its impact on skin wrinkle reduction, as well as its potential to en-hance skin elasticity and moisturization. COLLinstant® LMW was administered orally in a single-center, randomized, double-blind, placebo-controlled clinical trial. A sec-ondary objective involves comparing skin improvement, product satisfaction, and monitoring adverse events among middle-aged female volunteers., conditionsModule conditions: Facial Wrinkles, conditions: Skin Hydration, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized, Double-Blind, Placebo-Controlled Study, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: Randomized, Double-Blind, Placebo-Controlled Study, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 80, type: ACTUAL, armsInterventionsModule interventions name: Bioactive collagen peptides, interventions name: Placebo, outcomesModule primaryOutcomes measure: Skin wrinkling volume (px^3), primaryOutcomes measure: Skin wrinkling area (px^2), primaryOutcomes measure: Skin wrinkling depth (px), primaryOutcomes measure: R0= Skin firmness (mm), primaryOutcomes measure: R2= gross elasticity (%) of the skin, primaryOutcomes measure: R5= Skin net elasticity (%), primaryOutcomes measure: R7= Skin elastic recovery (%), primaryOutcomes measure: R9= Skin fatigue (mm), primaryOutcomes measure: Skin hydration (AU), secondaryOutcomes measure: Subjective perception of product efficacy, secondaryOutcomes measure: Subjective perception of the organoleptic characteristics of the product, secondaryOutcomes measure: Opinion on the degree of satisfaction with the product, eligibilityModule sex: FEMALE, minimumAge: 30 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: GALA Laboratories, city: Don Benito, state: Badajoz, zip: 06400, country: Spain, geoPoint lat: 38.95627, lon: -5.86162, hasResults: False
protocolSection identificationModule nctId: NCT06321757, orgStudyIdInfo id: EPIC30-PARIS, briefTitle: PREVAIL Paclitaxel-coated Balloon in Small Coronary Disease and High-bleeding Risk Patients, acronym: PARIS, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-26, primaryCompletionDateStruct date: 2025-09-30, completionDateStruct date: 2026-12-30, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Fundación EPIC, class: OTHER, descriptionModule briefSummary: Post-market, prospective, observational, multicenter, non-intervention study, to demonstrate the effectiveness of drug-coated ballon (DCB)therapy in real-world patients with small native vessel coronary artery disease, and to demonstrate the safety of short dual antiplatelet therapy (7 days) in high-bleeding risk patients with native small vessel coronary artery disease treated with DCB therapy. A percutaneous coronary intervention (PCI) with DCB will be performed in patients with native vessel coronary artery disease based on the criterion of the treating physician., conditionsModule conditions: Coronary Artery Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: PROSPECTIVE, enrollmentInfo count: 501, type: ESTIMATED, armsInterventionsModule interventions name: Percutaneous Coronary Intervention with DCB and DAPT, outcomesModule primaryOutcomes measure: Effectiveness of DCB therapy, secondaryOutcomes measure: Cardiac death, secondaryOutcomes measure: All-cause mortality, secondaryOutcomes measure: Target vessel myocardial infarction, secondaryOutcomes measure: New target lesion revascularization (TLR), secondaryOutcomes measure: Target vessel failure (TVF), secondaryOutcomes measure: Major bleeding, secondaryOutcomes measure: Minor bleeding, secondaryOutcomes measure: 1-year MACE indicende (cardiac mortality, myocardial infarction, and new revascularization of the target lesion) in high-bleeding risk patients treated with a short dual antiplatelet treatment (7 days), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hospital Universitario Clinico San Cecilio, status: RECRUITING, city: Granada, zip: 18016, country: Spain, geoPoint lat: 37.18817, lon: -3.60667, locations facility: Hospital Universitario Juan Ramon Jimenez, status: RECRUITING, city: Huelva, zip: 21005, country: Spain, geoPoint lat: 37.26638, lon: -6.94004, locations facility: Hospital Universitario de Leon, status: RECRUITING, city: León, zip: 24071, country: Spain, geoPoint lat: 42.60003, lon: -5.57032, locations facility: Hospital Universitario Y Politecnico La Fe, status: RECRUITING, city: Valencia, zip: 46026, country: Spain, geoPoint lat: 39.46975, lon: -0.37739, locations facility: Hospital Clinico Universitario de Valladolid, status: RECRUITING, city: Valladolid, zip: 47003, country: Spain, geoPoint lat: 41.65518, lon: -4.72372, hasResults: False
protocolSection identificationModule nctId: NCT06321731, orgStudyIdInfo id: D5980R00096, briefTitle: Real-World Outcomes in COPD Patients Starting Trixeo (Budesonide/Glycopyrronium/Formoterol) in Spain., acronym: ORESTES, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-30, primaryCompletionDateStruct date: 2024-11-30, completionDateStruct date: 2024-11-30, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: AstraZeneca, class: INDUSTRY, descriptionModule briefSummary: The aim of the ORESTES study is to describe the characteristics of the COPD patients initiating Trixeo (BGF -budesonide/glycopyrronium/formoterol) in Spain and to assess their real-world outcomes up to 12 months afterwards.For that purpose,a descriptive, observational, multi-centre, longitudinal, retrospective cohort study involving \~20 Spanish centres and aiming to include between 500 and 700 patients, has been designed., conditionsModule conditions: Chronic Obstructive Pulmonary Disease (COPD), designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 500, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: Annualized rate of exacerbations after BGF initiation, secondaryOutcomes measure: Demographic and clinical profile of patients initiating BGF., secondaryOutcomes measure: Lung Function after BGF initiation, secondaryOutcomes measure: Eosinophils count after BGF initiation, secondaryOutcomes measure: Persistence to treatment (BGF), secondaryOutcomes measure: Need for rescue medication after BGF initiation, secondaryOutcomes measure: Use of oral corticosteroids (OCS) after BGF initiation, secondaryOutcomes measure: HCRUs related to COPD after BGF initiation, otherOutcomes measure: Annualized rate of severe cardiovascular (CV)-related outcomes after initiation of BGF., otherOutcomes measure: Mortality (% and time to event) after BGF initiation, eligibilityModule sex: ALL, minimumAge: 40 Years, maximumAge: 130 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06321718, orgStudyIdInfo id: 04-2023-200629, briefTitle: Pericapsular Nerve Group Block vs Supra Inguinal Fascia Iliaca Compartment Block, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2025-03-01, completionDateStruct date: 2025-04-01, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: This study aims to assess the efficacy of PENG block performed with LFCN block in controlling postoperative pain and promoting motor function recovery and to compare its effectiveness with S-FICB., conditionsModule conditions: Pain, Postoperative, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: 96 Patients will be enrolled. Choice of type of anesthesia will be established according to every individual patient, but spinal anesthesia will be preferred over general anesthesia. The block will be administered under supervision of the supervisor senior staff before induction of anesthesia. 2 groups well be assessed1. Group (A) will receive PENG + LFCN block2. The second group (B): S-FICB, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: Through website computer program randomization program to distribute cases into two groups using their order number, whoMasked: PARTICIPANT, enrollmentInfo count: 96, type: ESTIMATED, armsInterventionsModule interventions name: PENG + LFCN block versus S-FICB, outcomesModule primaryOutcomes measure: recording time for "return of full muscle power", secondaryOutcomes measure: • The degree of hip flexion on the operative side, secondaryOutcomes measure: • Static and dynamic pain scores., secondaryOutcomes measure: postoperative nausea and vomiting (PONV) scale, secondaryOutcomes measure: • The number of rescue analgesia, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06321705, orgStudyIdInfo id: CS1-004, briefTitle: Safety and Efficacy of Continued CS1 Treatment of Patients With Pulmonary Arterial Hypertension, statusModule overallStatus: AVAILABLE, studyFirstPostDateStruct date: 2024-03-20, lastUpdatePostDateStruct date: 2024-03-20, sponsorCollaboratorsModule leadSponsor name: Cereno Scientific AB, class: INDUSTRY, collaborators name: Worldwide Clinical Trials, collaborators name: Abbott, descriptionModule briefSummary: CS1-004 will be an extension of the CS1-003 Study. The primary objective of the CS1-004 study is to evaluate long-term safety and tolerability of continued treatment with CS1., conditionsModule conditions: Pulmonary Arterial Hypertension, designModule studyType: EXPANDED_ACCESS, armsInterventionsModule interventions name: CS1, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Fredrik Frick, status: AVAILABLE, city: Gothenburg, country: Sweden, contacts name: Fredrik Frick, role: CONTACT, phone: +46725479566, email: Fredrik.Frick@cerenoscientific.com, geoPoint lat: 57.70716, lon: 11.96679, hasResults: False