hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06286995, orgStudyIdInfo id: 6280, briefTitle: Postoperative Pain Assessment After Canal Preparation by Different NiTi File Systems, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-10-14, primaryCompletionDateStruct date: 2024-01-29, completionDateStruct date: 2024-02-14, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: Ain Shams University, class: OTHER, descriptionModule briefSummary: The participants were divided into two groups : group one ( Trunatomy file group)(n=10) was mechanically prepared the canals by Trunatomy file and group two ( Edgeendo x7 file group) ( n=10) was prepared the canals by Edgeendo x7 file, the participants were assessed pain preoperatively and postoperatively by Visual Analog Scale(VAS), conditionsModule conditions: Post Operative Pain, conditions: Inflammation, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: This study was designed to be randomized,single- blinded, single-center clinical trial, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: A) Sequence generation: was done using random sequence number generated by computer software B) Allocation concealment Mechanism:folded,numbered papers were placed in tightly sealed envelopes containing patients' coding, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 20, type: ACTUAL, armsInterventionsModule interventions name: Chemomechanical preparation for root canals, outcomesModule primaryOutcomes measure: Level of post operative pain using 10-cm visual analogue scale ( VAS), secondaryOutcomes measure: Level of inflammatory mediators substance P in apical fluid samples, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule locations facility: Ain Shams university, city: Cairo, country: Egypt, geoPoint lat: 30.06263, lon: 31.24967, hasResults: False
protocolSection identificationModule nctId: NCT06286982, orgStudyIdInfo id: OASIS III, briefTitle: The Oral Symptom Assessment Scale in Older Patients With Frailty, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-06-06, primaryCompletionDateStruct date: 2024-07-06, completionDateStruct date: 2024-07-06, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-03-07, sponsorCollaboratorsModule leadSponsor name: Our Lady's Hospice and Care Services, class: OTHER, descriptionModule briefSummary: Oral (or mouth) symptoms are common in older patients who live with frailty. It is known that frailty describes someone's overall resilience and how this relates to the chances of recovery following a health problem. A questionnaire called the Oral Symptom Assessment Scale (or OSAS) was designed to look at mouth symptoms in patients who had an advanced cancer. These symptoms may overlap with patients who have frailty.This research study is taking place to find out if the OSAS will be a suitable questionnaire that can be used in older patients with frailty.This study will take place in Our Lady's Hospice \& Care Services, Harold's Cross and St James' Hospital over six months., conditionsModule conditions: Frailty, conditions: Older Adults, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 250, type: ESTIMATED, armsInterventionsModule interventions name: Oral Symptom Assessment Scale, outcomesModule primaryOutcomes measure: To determine the prevalence of oral symptoms in older patients with frailty, primaryOutcomes measure: To determine the clinical features of these oral symptoms in this group (i.e. frequency, severity and level of distress), primaryOutcomes measure: To determine the relationship between oral symptoms and Clinical Frailty Score / Cumulative Illness Rating Scale for Geriatrics/Medications, primaryOutcomes measure: To provide initial validation of OSAS in older patients with frailty, eligibilityModule sex: ALL, minimumAge: 65 Years, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: St James's Hospital, status: RECRUITING, city: Dublin, zip: D8, country: Ireland, contacts name: Niamh Cleary, MB MICGP, role: CONTACT, phone: +353876603466 (Ireland), email: clearynm@tcd.ie, contacts name: Amanda Lavan, PhD MRCPI, role: SUB_INVESTIGATOR, contacts name: Roman Romero Ortuno, MSc PhD MRCP, role: SUB_INVESTIGATOR, geoPoint lat: 53.33306, lon: -6.24889, locations facility: Our Lady's Hospice and Care Services, status: RECRUITING, city: Dublin, zip: Dublin 6W, country: Ireland, contacts name: Niamh M Cleary, MB MICGP, role: CONTACT, phone: +353876603466 (Ireland), email: clearynm@tcd.ie, contacts name: Norah Fagan, RGN MSc, role: SUB_INVESTIGATOR, geoPoint lat: 53.33306, lon: -6.24889, hasResults: False
protocolSection identificationModule nctId: NCT06286969, orgStudyIdInfo id: ZSLL-ZN-2024-007-01, briefTitle: Clinical Study on Intensive Multi-acupuncture in the Treatment of Lumbar Muscle Strain., statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2025-03-01, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: Xu Xinnan, class: OTHER, descriptionModule briefSummary: Acupuncture is widely used as a routine treatment for lumbar muscle strain. The aim of this randomized controlled trial is to evaluate the effectiveness of the intensive multi-acupuncture method. This trial will include 108 patients with lumbar muscle strain injury from two outpatient clinics. All participants will be randomized in a 1:1 ratio to the intensive multi-acupuncture method group and the normal needling group. Outcomes will be assessed before the intervention, after one treatment, after five treatments, and at follow-up 2 weeks after the end of treatment. The primary outcome indicator will be the clinical efficacy evaluation criteria, and the secondary outcome indicators will be the pain visual analog scale (VAS) score, the Japanese Orthopaedic Association Assessment Treatment Score (JOA) score, the lumbar joint mobility measurement scale, and the Modified Ashworth Grading Scale. This study will provide evidence as to whether the intensive multi-acupuncture method is safe and effective., conditionsModule conditions: Lumbar Muscle Strain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 108, type: ESTIMATED, armsInterventionsModule interventions name: acupuncture, outcomesModule primaryOutcomes measure: clinical efficacy evaluation criteria, secondaryOutcomes measure: Pain visual analog scale (VAS) score, secondaryOutcomes measure: Japanese Orthopaedic Association Scores, secondaryOutcomes measure: Lumbar Joint Mobility Measurement Scale, secondaryOutcomes measure: Improvement of the Ashworth Rating Scale, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06286930, orgStudyIdInfo id: STU-2023-0470, briefTitle: Cerebellar tDCS Stimulation in Children and Adult Women With Anorexia Nervosa Disorder, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-01-02, completionDateStruct date: 2026-01-02, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: University of Texas Southwestern Medical Center, class: OTHER, descriptionModule briefSummary: Hypothesis: Will the use of tDCS brain modulation in the cerebellum assist in restricted behaviors, social cognition and cognitive flexibility in women with anorexia nervosa in addition to other therapies?Primary Outcomes:1. To observe the impacts and outcomes of cerebellar transcranial direct current stimulation (tDCS) on social behaviors measured by Cyberball and Trust Game.2. To observe the neuropsychological impacts of cerebellar tDCS through fMRI imaging as well as looking at the Region of Interest (ROI) of changes in the Default Mode Network and Cerebellum circuits and their activation levels in those networks.Secondary Outcomes:1.To observe the impacts and outcome of cerebellar transcranial direct current stimulation (tDCS) measuring the differences between anodal and cathodal stimulation. To observe potential increases in responses to social stimuli, decreases in eating disorder/depressive symptomology via cathodal stimulation. To also observe potential little to no changes in social stimuli and eating disorder/depressive symptomology via anodal stimulation., conditionsModule conditions: Anorexia Nervosa, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 15, type: ESTIMATED, armsInterventionsModule interventions name: anodal trans cranial direct current stimulation (tDCS), interventions name: cathodal trans cranial direct current stimulation (tDCS), outcomesModule primaryOutcomes measure: tDCS impact on social behaviors using Cyberball, primaryOutcomes measure: tDCS impact on social behaviors using the Trust Game, primaryOutcomes measure: neurological impacts of tDCS as measured by fMRI imaging, secondaryOutcomes measure: measure the differences of social stimuli and eating disorder/depressive symptomology, secondaryOutcomes measure: measure the differences of social stimuli and eating disorder/depressive symptomology, secondaryOutcomes measure: measuring the differences of social stimuli and eating disorder/depressive symptomology measuring using the Food Rating Task., secondaryOutcomes measure: measure the differences of social stimuli and mental flexibility with Trail Making Task, secondaryOutcomes measure: measure the differences of social stimuli and eating disorder/depressive symptomology utilizing Patient Health Questionnaire-9., eligibilityModule sex: FEMALE, minimumAge: 15 Years, maximumAge: 30 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06286917, orgStudyIdInfo id: R24001, briefTitle: Initiation of Noninvasive Ventilation in ALS Patients With Chronic Respiratory Insufficiency, acronym: InNIVALS, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-05, primaryCompletionDateStruct date: 2028-12, completionDateStruct date: 2029-12, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Tampere University, class: OTHER, descriptionModule briefSummary: This research will study whether noninvasive ventilation (NIV) used to treat chronic respiratory insufficiency in patients with amyotrophic lateral sclerosis (ALS) can be initiated as successfully in the outpatient setting as in the conventional inpatient setting, and what the costs of these alternative initiation methods are., conditionsModule conditions: Ventilation Therapy, conditions: ALS, conditions: Chronic Respiratory Failure, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: SINGLE, whoMasked: INVESTIGATOR, enrollmentInfo count: 120, type: ESTIMATED, armsInterventionsModule interventions name: NIV initiation in patients with ALS, outcomesModule primaryOutcomes measure: NIV usage hours according to different initiation locations in patients with ALS, primaryOutcomes measure: Compliance with NIV according to NIV initiation setting in patients with ALS, primaryOutcomes measure: Decrease in blood carbon dioxide levels in patients with ALS depending on the place of NIV initiation., otherOutcomes measure: Costs of initiation of NIV in outpatient setting compared with inpatient setting in patients with ALS, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 99 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Tampere University Hospital, status: RECRUITING, city: Tampere, zip: 33520, country: Finland, contacts name: Heidi A Rantala, MD, PhD, role: CONTACT, phone: +3583311611, email: heidi.rantala@tuni.fi, contacts name: Lauri Lehtimäki, MD, PhD, role: CONTACT, phone: +3583311611, email: lauri.lehtimaki@tuni.fi, contacts name: Hanna Korkeamäki, MD, MSc, role: PRINCIPAL_INVESTIGATOR, contacts name: Hannele Hasala, MD, PhD, role: SUB_INVESTIGATOR, contacts name: Sirpa Leivo-Korpela, MD, PhD, role: SUB_INVESTIGATOR, geoPoint lat: 61.49911, lon: 23.78712, hasResults: False
protocolSection identificationModule nctId: NCT06286904, orgStudyIdInfo id: McMaster-Myant 16633, briefTitle: Sleep Position Pattern Recording, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2024-12-01, completionDateStruct date: 2025-03-30, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: Myant Medical Corp., class: INDUSTRY, collaborators name: McMaster University, descriptionModule briefSummary: The main goal of this study is to validate the accuracy of the body position detection by non-invasive wearable monitors (Skiin garments, Myant Medical Corp) during sleep in pregnant participants. This is a first step towards examining the association between maternal sleep position and fetal growth., conditionsModule conditions: Pregnant Women, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 52, type: ESTIMATED, armsInterventionsModule interventions name: Skiin Garment system, outcomesModule primaryOutcomes measure: Accuracy of Skiin Garment system for detecting sleep position of pregnant women, secondaryOutcomes measure: Questionnaire on wearable device invasiveness and satisfaction, secondaryOutcomes measure: Participant recruitment rate, secondaryOutcomes measure: Participant retention rate, eligibilityModule sex: FEMALE, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: McMaster University, city: Hamilton, state: Ontario, zip: L8S 4K1, country: Canada, contacts name: Kyle McGowan, role: CONTACT, phone: 905.521.2100, phoneExt: 21334, email: mcgowank@mcmaster.ca, contacts name: Eran Ashwal, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 43.25011, lon: -79.84963, hasResults: False
protocolSection identificationModule nctId: NCT06286891, orgStudyIdInfo id: CAAE: 73520523.7.0000.0068, briefTitle: Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-29, primaryCompletionDateStruct date: 2024-11-01, completionDateStruct date: 2025-09-30, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-03-19, sponsorCollaboratorsModule leadSponsor name: University of Sao Paulo General Hospital, class: OTHER, descriptionModule briefSummary: The goal of this observational and prospective study is to investigate changes in physical performance, lung function, respiratory and peripheral muscle strength in patients during the postoperative period following pulmonary endarterectomy (PET)., conditionsModule conditions: Chronic Thromboembolic Pulmonary Hypertension, conditions: Physical Disability, conditions: Fragility, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 50, type: ESTIMATED, outcomesModule primaryOutcomes measure: To investigate changes in physical performance measured by Six-Minute Walk Test., primaryOutcomes measure: To investigate changes in physical performance measured by Short Physical Performance Battery (SPPB)., primaryOutcomes measure: To investigate changes in physical performance by 1-minute sit-to-stand test (1-MSTST)., primaryOutcomes measure: To investigate changes in peripheral muscle strength., primaryOutcomes measure: To investigate changes in respiratory muscle strength:, primaryOutcomes measure: To investigate changes in lung function test measure by spirometry:, primaryOutcomes measure: To investigate frailty by Clinical Frailty Scale (CFS), secondaryOutcomes measure: To explore potential preoperative and immediate postoperative risk factors as predictors of functional loss., secondaryOutcomes measure: To investigate changes in hemodynamic and respiratory variables during the funcional tests., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Instituto do Coração - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, status: RECRUITING, city: São Paulo, state: SP, zip: 05403-000, country: Brazil, contacts name: Orival Freitas Filho, MD, role: SUB_INVESTIGATOR, contacts name: Fabio B Jatene, MD,PhD, role: SUB_INVESTIGATOR, contacts name: Kelly CO Abud, PT, PhD, role: SUB_INVESTIGATOR, geoPoint lat: -23.5475, lon: -46.63611, hasResults: False
protocolSection identificationModule nctId: NCT06286865, orgStudyIdInfo id: 260972(REK), briefTitle: Improving Quality of ICD-10 Coding Using AI: Protocol for a Crossover Randomized Controlled Trial, acronym: ClinCode, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-10-20, primaryCompletionDateStruct date: 2024-04, completionDateStruct date: 2024-04, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: University Hospital of North Norway, class: OTHER, collaborators name: The Research Council of Norway, descriptionModule briefSummary: The goal of this randomised trial is to learn about the role of AI in clinical coding practice. The main question it aims to answer is:Can the AI-based CAC system reduce the burden of clinical coding and also improve the quality of such coding? Participants will be asked to code clinical texts both while they use our CAC system and while they do not., conditionsModule conditions: Gastrointestinal Diseases, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: DIAGNOSTIC, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Easy-ICD, outcomesModule primaryOutcomes measure: Time, primaryOutcomes measure: Accuracy, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Norwegian Centre for E-health Research, status: RECRUITING, city: Tromso, state: Troms, zip: 9019, country: Norway, contacts name: Taridzo F Chomutare, PhD, role: CONTACT, phone: +4747680032, email: taridzo.chomutare@ehealthresearch.no, contacts name: Hercules Dalianis, PhD, role: CONTACT, phone: +46705681359, email: hercules@dsv.su.se, geoPoint lat: 69.6489, lon: 18.95508, hasResults: False
protocolSection identificationModule nctId: NCT06286852, orgStudyIdInfo id: EDE BA, briefTitle: Italian Language Validation of The Eating Disorder Examination (EDE) - Child Version, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2022-11-01, primaryCompletionDateStruct date: 2023-12-30, completionDateStruct date: 2024-06-30, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: Meyer Children's Hospital IRCCS, class: OTHER, descriptionModule briefSummary: Although eating disorders often occur during or after puberty, it is likely that critical antecedent conditions can be established before adolescence. The Eating Disorder Examination has been adapted for children and is described by Bryant - Waugh, Cooper, Taylor and Lask (1996). The EDE is considered the gold standard of measures of eating disorder psychopathology (Wilson, 1993), and this adaptation, which allows its use with a younger age group, is a potentially important addition to the assessment of eating disorders in children. The latest version of EDE, the l7th edition, has now surpassed its predecessors.The aim of the study is to evaluate the psychometric properties of the Child vers ion EDE (chEDE) translated into Italian, in a sample of patients with eating disorder, conditionsModule conditions: Feeding and Eating Disorders of Childhood, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 250, type: ESTIMATED, armsInterventionsModule interventions name: Administration of K-SADS-PL- Kiddie-Schedule for Affective Disorder and Schizophrenia-Present and Lifetime version (Kaufmann, 2002), interventions name: Administration of ChEDE- Child Version of the EatingDisorder Examination, outcomesModule primaryOutcomes measure: K-SADS-PL (Kiddie-Schedule for Affective Disorder and Schizophrenia-Present and Lifetime version) questionnaire, primaryOutcomes measure: ChEDE (Child Version of the EatingDisorder Examination), eligibilityModule sex: ALL, minimumAge: 8 Years, maximumAge: 17 Years, stdAges: CHILD, contactsLocationsModule locations facility: Meyer Children's Hospital IRCCS, city: Firenze, country: Italy, geoPoint lat: 43.77925, lon: 11.24626, locations facility: USL Toscana Centro, city: Firenze, country: Italy, geoPoint lat: 43.77925, lon: 11.24626, locations facility: Ospedale Villa Garda, city: Garda, country: Italy, geoPoint lat: 45.57889, lon: 10.71763, hasResults: False
protocolSection identificationModule nctId: NCT06286839, orgStudyIdInfo id: AFCRO-150, briefTitle: Study of Cannabidiol (CBD) in Healthy Volunteers, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-05-12, primaryCompletionDateStruct date: 2022-10-28, completionDateStruct date: 2022-12-14, studyFirstPostDateStruct date: 2024-02-29, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: NextEvo Inc., class: INDUSTRY, collaborators name: Atlantia Food Clinical Trials, descriptionModule briefSummary: This was a prospective, single-centre, open label, randomized, two-arm, parallel design study to evaluate the effect of four-weeks consumption of active study product on primary endpoint in healthy adults, conditionsModule conditions: Immune System and Related Disorders, conditions: Immune System Diseases, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 26, type: ACTUAL, armsInterventionsModule interventions name: Cannabidiol (CBD), outcomesModule primaryOutcomes measure: Plasma CBD pharmacokinetics of twice daily intake of 2 different doses of CBD over three days, primaryOutcomes measure: Evaluate the safety of twice daily intake of 2 different doses of CBD over three 3 days, secondaryOutcomes measure: Plasma CBD maximal concentration (Cmax, ng/ml), secondaryOutcomes measure: Plasma CBD time to peak (Tmax, minutes), secondaryOutcomes measure: Percentage Change between groups on whole blood LPS stimulated cytokines (% change), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule locations facility: Altantia Clinical Trials, city: Chicago, state: Illinois, zip: 60611, country: United States, geoPoint lat: 41.85003, lon: -87.65005, hasResults: False