hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06276738, orgStudyIdInfo id: Adenocyte 102, briefTitle: The LINFU® U.S. Registry in Patients With Clinical Signs and/or Symptoms of Disease, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-30, primaryCompletionDateStruct date: 2034-03-01, completionDateStruct date: 2034-05-01, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-29, sponsorCollaboratorsModule leadSponsor name: Adenocyte, LLC, class: INDUSTRY, descriptionModule briefSummary: Evaluate LINFU® in patients who exhibit signs or symptoms (i.e. jaundice, abdominal pain, weight loss, nausea and vomiting etc.) suggestive of pancreatic cancer (PDAC) or have evidence of imaging studies suggestive of PDAC., conditionsModule conditions: Pancreatic Cancer, conditions: Jaundice, conditions: Abdominal Neoplasm, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 1000, type: ESTIMATED, armsInterventionsModule interventions name: LINFU® (Low Intensity Non-Focused Ultrasound excitation of the pancreas), outcomesModule primaryOutcomes measure: The number of pancreatic ductal adenocarcinomas identified only with LINFU® will be compared to standard screening methods, secondaryOutcomes measure: The change in size of pancreatic ductal adenocarcinomas identified only with LINFU® will be determined, secondaryOutcomes measure: Determine the number of patients with pancreatic ductal adenocarcinoma identified only with LINFU® that require medical or surgical intervention, otherOutcomes measure: Yearly survival rate of patients with pancreatic ductal adenocarcinomas identified only with LINFU®, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 90 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06276712, orgStudyIdInfo id: UNISS_PHD_Osstem_5, briefTitle: RCT Comparing KS Versus TS for Ovedenture, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-12-30, completionDateStruct date: 2028-01-30, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Università degli Studi di Sassari, class: OTHER, collaborators name: Dr. Dario Melodia, collaborators name: Dr. Milena Pisano, collaborators name: Dr. Aurea Lumbau, collaborators name: Prof. Silvio Mario Meloni, collaborators name: Prof. Edoardo Baldoni, descriptionModule briefSummary: To evaluate the clinical and radiographic outcomes of KS implants used to rehabilitate edentulous mandible with dental-retained overdentures, and to compare it with same treatment on TS implants, conditionsModule conditions: Dental Implant, conditions: Dental Implant-Abutment Design, conditions: Edentulous Jaw, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: A multicenters, randomized controlled trial., primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: A blinded (when possible) outcome assessor will evaluate all the outcomes and will take the radiogram for centralized analysis., whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 48, type: ESTIMATED, armsInterventionsModule interventions name: Implant placement with 3.5 mm diameter KS implants., interventions name: Implant placement with 3.5 mm diameter TS implants., outcomesModule primaryOutcomes measure: Number of implant failure, primaryOutcomes measure: Number of prosthesis failure, primaryOutcomes measure: Number of complications, primaryOutcomes measure: Rate of implant stability, secondaryOutcomes measure: Peri-implant marginal bone level changes, secondaryOutcomes measure: Patient satisfaction, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06276699, orgStudyIdInfo id: FAHS, briefTitle: Efficacy of a Combination of Conservative Treatments Compared to Isometric Exercise on Clinical Outcomes in Patients With Cervical Radiculopathy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2024-05, completionDateStruct date: 2024-06, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-04-16, sponsorCollaboratorsModule leadSponsor name: University of Peradeniya, class: OTHER, descriptionModule briefSummary: This intervention study is to evaluate the efficacy of a combination of conservative treatments compared to isometric exercise on clinical outcomes in patients with cervical radiculopathy. It is a randomized, parallel, 2-arm superiority trial study. The study will be conducted at the District General Hospital in Trincomalee, where patients with cervical radiculopathy seek medical care. Patients who refer to the Department of Physical Medicine (DPM) from the Out Patients Department (OPD), orthopedic clinic and surgical clinic with a diagnosis of cervical radiculopathy or neck and arm pain (symptoms extending distal to the shoulder) will be eligible for recruitment. The study details will be explained to the subjects in the language that they best understand. Written informed consent will be obtained from the individuals who express their willingness to participate in the study, and they will sign the informed consent document accordingly., conditionsModule conditions: Cervical Radiculopathy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 46, type: ESTIMATED, armsInterventionsModule interventions name: 1.Isometric exercise 2.combined conservative treatment, outcomesModule primaryOutcomes measure: Difference in pain intensity measured by Visual Analogue Scale (VAS) between combination of treatments and isometric exercises at 6-weeks post-baseline., secondaryOutcomes measure: Difference in cervical ROM measured by Goniometry between combination of treatments and isometric exercises at 6-weeks post-baseline., secondaryOutcomes measure: Difference in functional disability measured by Neck Disability Index between combination of treatments and isometric exercises at 6-weeks post-baseline, eligibilityModule sex: ALL, minimumAge: 35 Years, maximumAge: 60 Years, stdAges: ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06276686, orgStudyIdInfo id: RS211 - 332296, briefTitle: Exercise for Improving Long-course Chemoradiotherapy Efficacy in People With Locally Advanced Rectal Cancer, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06, primaryCompletionDateStruct date: 2026-01, completionDateStruct date: 2026-02, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: University of Hull, class: OTHER, collaborators name: Hull University Teaching Hospitals NHS Trust, descriptionModule briefSummary: This is a single arm feasibility study of exercise for improving long- course neoadjuvant chemoradiotherapy (NACRT) efficacy in people diagnosed with locally advanced rectal cancer. The study aims to recruit up to 30 patients from the Queen's Centre for Oncology and Haematology of Castle Hill Hospital, Cottingham, diagnosed with locally advanced rectal cancer. Consenting patients will be provided with an 11-week course of structured aerobic exercises and resistance training in the periods before, during and after their chemoradiotherapy treatment. The patients will be followed up for 6 months post long course neoadjuvant chemoradiotherapy (NACRT), with a total of 3 assessment periods., conditionsModule conditions: Locally Advanced Rectal Carcinoma, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Supervised Vigorous intensity aerobic interval exercise, outcomesModule primaryOutcomes measure: Recruitment rate, primaryOutcomes measure: Attendance rate, primaryOutcomes measure: withdrawal rate, secondaryOutcomes measure: Serum Carcinoembryonic antigen levels, secondaryOutcomes measure: Quality of life, secondaryOutcomes measure: Quality of life, secondaryOutcomes measure: Physical activity levels, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06276673, orgStudyIdInfo id: 301, briefTitle: The Influences of Single Chamber vs. Multi-chamber Blood Flow Restriction Cuffs, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-02-13, primaryCompletionDateStruct date: 2024-11-10, completionDateStruct date: 2024-12-10, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Salisbury University, class: OTHER, descriptionModule briefSummary: The purpose of this study is to investigate the use of single (SC) and multi-chamber (MC) blood flow restriction (BFR) cuff exercise on indices of arterial stiffness, muscle morphology, and participant perception., conditionsModule conditions: Blood Vessel Disease, conditions: Muscle Edema, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: Participants will undergo three treatment sessions (control (no BFR), SC BFR, and MC BFR) in a randomized order separated by one week., primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, maskingDescription: Unable to blind due to differences in cuff size and appearance., enrollmentInfo count: 35, type: ESTIMATED, armsInterventionsModule interventions name: Delfi, outcomesModule primaryOutcomes measure: Arterial Stiffness, primaryOutcomes measure: Muscle Morphology, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Salisbury University, city: Salisbury, state: Maryland, zip: 21801, country: United States, geoPoint lat: 38.36067, lon: -75.59937, hasResults: False
protocolSection identificationModule nctId: NCT06276660, orgStudyIdInfo id: STUDY23070079, briefTitle: Post-Concussion Differences Between Buffalo Concussion Treadmill Test (BCTT) and Modified Dynamic Exertion (mEXiT) Test, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-05, primaryCompletionDateStruct date: 2024-09, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: University of Pittsburgh, class: OTHER, descriptionModule briefSummary: This study aims to compare symptom provocation, physiologic response, and rate of perceived (RPE) between the Buffalo Concussion Treadmill Test (BCTT) and a Modified Dynamic Exertion (mEXiT) test after sport related concussion in adolescents aged 14-17. Participants will be enrolled at their initial concussion clinical visit within 14 days of their injury, and randomly assigned to either the BCTT or mEXiT group. Participants will complete a single visit., conditionsModule conditions: Mild Traumatic Brain Injury, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: NONE, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: BCTT, interventions name: Dynamic ExIT, outcomesModule primaryOutcomes measure: Physiological response to dynamic or aerobic test (HEART RATE), secondaryOutcomes measure: Post Concussion Symptom Scale, secondaryOutcomes measure: Patient Health Questionnaire (PHQ-9), secondaryOutcomes measure: Generalized Anxiety Disorder (GAD-7), secondaryOutcomes measure: Vestibular Ocular Motor Screening (VOMS), secondaryOutcomes measure: Clinical Profiles Screening (CP-Screen), secondaryOutcomes measure: Blood Pressure, eligibilityModule sex: ALL, minimumAge: 14 Years, maximumAge: 17 Years, stdAges: CHILD, contactsLocationsModule locations facility: UPMC/Univ of Pgh Sports Medicine Concussion Research Program, status: RECRUITING, city: Pittsburgh, state: Pennsylvania, zip: 15203, country: United States, contacts name: Cynthia Holland, MPH, role: CONTACT, phone: 412-904-1298, email: clh197@pitt.edu, geoPoint lat: 40.44062, lon: -79.99589, hasResults: False
protocolSection identificationModule nctId: NCT06276647, orgStudyIdInfo id: 850584, secondaryIdInfos id: R01MD016029, type: NIH, link: https://reporter.nih.gov/quickSearch/R01MD016029, briefTitle: Improving Health Outcomes and Equity by Targeting Postpartum Mothers at Highest Risk, acronym: HOME, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-20, primaryCompletionDateStruct date: 2025-02-15, completionDateStruct date: 2025-05-31, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: University of Pennsylvania, class: OTHER, collaborators name: National Institutes of Health (NIH), collaborators name: Columbia University, collaborators name: National Institute on Minority Health and Health Disparities (NIMHD), descriptionModule briefSummary: The goal of this educational clinical trial is to identify Black women most at risk for poor outcomes following delivery, the problems they experience, and to create a system to improve quality of postpartum care for high-risk women. The main question\[s\] it aims to answer are:* How can the investigators help postpartum Black people who have poor outcomes by decreasing the number of ED visits/readmissions for postpartum people within the first 30 days postpartum?* How can the investigators increase the ability of participants to "obtain needed services" and ability for patients to see their provider when they need to, in the 30-day post discharge period as one of the main pathways of unnecessary ED visits?Participants will be put into the study group or control group. The study group will receive a pamphlet postpartum with helpful information as well as a patient navigator who the participants will be able to reach out to their first 30 days postpartum., conditionsModule conditions: Maternal Behavior, conditions: Postpartum Depression, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 214, type: ESTIMATED, armsInterventionsModule interventions name: HOME, outcomesModule primaryOutcomes measure: Emergency Department (ED) Visits and Readmissions, secondaryOutcomes measure: Ability to Obtain Needed Services, secondaryOutcomes measure: Depressive Symptoms, secondaryOutcomes measure: Depressive Symptoms, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule locations facility: Hospital of the University of Pennsylvania, status: RECRUITING, city: Philadelphia, state: Pennsylvania, zip: 19104, country: United States, contacts name: Elizabeth Howell, MD MPP, role: CONTACT, email: elizabeth.howell1@pennmedicine.upenn.edu, contacts name: Micki Burdick, PhD, role: CONTACT, email: micki.burdick@pennmedicine.upenn.edu, contacts name: Elizabeth Howell, MD MPP, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 39.95233, lon: -75.16379, hasResults: False
protocolSection identificationModule nctId: NCT06276634, orgStudyIdInfo id: STU00219535, secondaryIdInfos id: R21HD108587, type: NIH, link: https://reporter.nih.gov/quickSearch/R21HD108587, briefTitle: Intermittent Hypoxia in Persons With Multiple Sclerosis, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2026-01, completionDateStruct date: 2027-01, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Shirley Ryan AbilityLab, class: OTHER, collaborators name: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), collaborators name: Northwestern University, descriptionModule briefSummary: This study aims to understand the mechanisms of a novel intervention involving breathing short durations of low levels of oxygen for persons with multiple sclerosis (MS). This intervention with low levels of oxygen is called Acute Intermittent Hypoxia (AIH), the levels of oxygen experienced are similar to breathing the air on a tall mountain, for less than 1 minute at a time. Previous studies have shown that AIH is a safe and effective way to increase strength in persons with MS. Here the investigators aim to look at brain activation and ankle strength before and after AIH to gain a better understanding of how the AIH may improve strength in those persons with MS., conditionsModule conditions: Multiple Sclerosis, conditions: Multiple Sclerosis-Relapsing-Remitting, conditions: Multiple Sclerosis, Secondary Progressive, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: Randomized, double-blind, placebo-controlled, cross-over, repeated measures study design, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 21, type: ESTIMATED, armsInterventionsModule interventions name: Acute Intermittent Hypoxia, interventions name: Sham-Acute Intermittent Hypoxia, outcomesModule primaryOutcomes measure: Ankle Plantarflexion Strength, secondaryOutcomes measure: Task fMRI, otherOutcomes measure: Timed 25 Feet Walk test, otherOutcomes measure: Six-Minute Walk test, otherOutcomes measure: Stride length, otherOutcomes measure: 12-Item Multiple Sclerosis walk scale (MSWS-12), otherOutcomes measure: Resting-State fMRI, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Shirley Ryan AbilityLab, city: Chicago, state: Illinois, zip: 60611, country: United States, contacts name: Alexander Barry, MS, CCRC, role: CONTACT, phone: 312-238-1435, email: abarry@sralab.org, contacts name: Milap Sandhu, PT, PhD, role: PRINCIPAL_INVESTIGATOR, contacts name: Molly Bright, D.Phil., role: SUB_INVESTIGATOR, geoPoint lat: 41.85003, lon: -87.65005, hasResults: False
protocolSection identificationModule nctId: NCT06276608, orgStudyIdInfo id: PED_Fe_def, briefTitle: Iron Deficiency in Pediatric Heart Surgery, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-23, primaryCompletionDateStruct date: 2024-04-20, completionDateStruct date: 2024-06-30, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Queen Fabiola Children's University Hospital, class: OTHER, descriptionModule briefSummary: The prevalence of iron deficiency in pediatric cardiac surgery patients is not very well known. Iron deficiency can lead to anemia, higher transfusion rates and possibly higher complication rates. In this retrospective study, the iron status of all patients undergoing pediatric cardiac surgery at our institution between January 2019 and december 2023 will be analyzed. Together with iron status, transfusion requirements as well as complications will be recorded. Iron status will be reported with descriptive statistics, patients with or without iron deficiency will be compared using non-parametric tests., conditionsModule conditions: Iron Deficiencies, conditions: Iron Deficiency Anemia, conditions: Cardiac Surgical Procedures, conditions: Congenital Heart Disease in Children, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 300, type: ESTIMATED, armsInterventionsModule interventions name: Iron status, outcomesModule primaryOutcomes measure: Prevalence of preoperative iron deficiency (%), primaryOutcomes measure: Complications, eligibilityModule sex: ALL, maximumAge: 16 Years, stdAges: CHILD, contactsLocationsModule locations facility: H.U.B - Hôpital Universitaire des Enfants Reine Fabiola, status: RECRUITING, city: Brussels, zip: 1020, country: Belgium, contacts name: Denis Schmartz, MD, role: CONTACT, phone: +3225553919, email: denis.schmartz@hubruxelles.be, geoPoint lat: 50.85045, lon: 4.34878, hasResults: False
protocolSection identificationModule nctId: NCT06276595, orgStudyIdInfo id: IRB00009466, briefTitle: Telling Our Daughters Our Story, acronym: TODOS, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2019-03-30, primaryCompletionDateStruct date: 2022-03-22, completionDateStruct date: 2024-07-30, studyFirstPostDateStruct date: 2024-02-26, lastUpdatePostDateStruct date: 2024-02-26, sponsorCollaboratorsModule leadSponsor name: Johns Hopkins Bloomberg School of Public Health, class: OTHER, collaborators name: White Mountain Apache Tribe, collaborators name: Native American Research Centers for Health, descriptionModule briefSummary: The objective of this research study is to evaluate a culturally grounded program among American Indian (AI) female children and the children's female caregivers. This project will evaluate the impact of "Nowhi Isdza bit Nadagoldi: Telling Our Daughters Our Story (henceforth referred to as TODOS) on associated risk and protective factors for early substance use and sexual debut through a randomized controlled trial on the White Mountain Apache (WMA) reservation. The investigators will examine whether the TODOS program effectively reduces risk factors and improves protective factors associated with early substance use and sexual debut, with long term goals of reducing teen pregnancy and teen substance use., conditionsModule conditions: Substance Use, conditions: Sexual Behavior, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 183, type: ACTUAL, armsInterventionsModule interventions name: Nowhi Isdza bit Nadagoldi: Telling Our Daughters Our Story (TODOS), interventions name: Control condition - 3 Monthly Group Activities in the Community, outcomesModule primaryOutcomes measure: Change in child cultural knowledge score on knowledge assessment, primaryOutcomes measure: Change in average score on risky behaviors assessment, primaryOutcomes measure: Change in child reproductive health knowledge via a reproductive health knowledge questionnaire, eligibilityModule sex: FEMALE, minimumAge: 8 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: White Mountain Apache Center for Indigenous Health, city: Whiteriver, state: Arizona, zip: 85941, country: United States, geoPoint lat: 33.83699, lon: -109.96427, hasResults: False