protocolSection identificationModule nctId: NCT06360549, orgStudyIdInfo id: TJ-IRB202403019, briefTitle: Effect of Percutaneous Acupoint Electrical Stimulation on Delirium, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-12-30, completionDateStruct date: 2025-06-30, studyFirstPostDateStruct date: 2024-04-11, lastUpdatePostDateStruct date: 2024-04-11, sponsorCollaboratorsModule leadSponsor name: Qin Zhang, class: OTHER, collaborators name: National Natural Science Foundation of China, descriptionModule briefSummary: This study is a multicenter, prospective, randomized controlled clinical trial that aims to observe the impact of Transcutaneous Electrical Acupoint Stimulation (TEAS) on plasma TK/MMP3 in a randomized controlled setting. The intervention group received percutaneous acupoint electrical stimulation, whereas the control group underwent conventional treatment. The primary objective is to enhance the management of postoperative delirium, specifically focusing on the occurrence and severity of delirium following thoracoscopic pulmonary resection. Additionally, various perioperative inflammatory markers, cognitive function, recovery quality, pain levels, anxiety, sleep patterns, postoperative complications, and overall hospital stay duration were monitored to elucidate the mechanisms through which percutaneous acupoint electrical stimulation improves postoperative delirium., conditionsModule conditions: Delirium, Postoperative, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The intervention group was percutaneous acupoint electrical stimulation treatment group, and the control group was conventional treatment group.Inclusion criteria:1. Voluntarily sign informed consent;2. Age ≥18 years old;3. Patients undergoing thoracoscopic pneumonectomy;4. ASA Grade I-III;, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 238, type: ESTIMATED, armsInterventionsModule interventions name: Transcutaneous Electrical Acupoint Stimulation, outcomesModule primaryOutcomes measure: Delirium (using the Delirium Rating Scale, DRS), secondaryOutcomes measure: Mini-Mental State Examination (MMSE), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Guangdong Hospital of Traditional Chinese Medicine, status: NOT_YET_RECRUITING, city: Guangzhou, state: Guangdong, zip: 510000, country: China, contacts name: Jiemin Deng, role: CONTACT, phone: 2780, email: qin4298@sina.com, contacts name: Jiemin Deng, role: CONTACT, geoPoint lat: 23.11667, lon: 113.25, locations facility: Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, status: RECRUITING, city: Wuhan, state: Hubei, zip: 430030, country: China, contacts name: Qin Zhang, phd, role: CONTACT, phone: 15717154768, email: qzhang8@tjh.tjmu.edu.cn, contacts name: Qin Zhang, phd, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 30.58333, lon: 114.26667, hasResults: False