hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06379841, orgStudyIdInfo id: STUDY00007357, briefTitle: Green Hysteroscopy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2025-05, completionDateStruct date: 2025-05, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Emory University, class: OTHER, descriptionModule briefSummary: The purpose of this study is to determine whether green draping in the operating room prior to a hysteroscopy results in a decreased operating room time.Secondary aims are to determine whether there are any differences in infection rate, complication rate, fluid deficit, operating room turnover time, conditionsModule conditions: Hysteroscopy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Green Draping Procedure, interventions name: Full Draping Procedure, outcomesModule primaryOutcomes measure: Difference in operative times, secondaryOutcomes measure: Infection Rate, secondaryOutcomes measure: Post Operative complication Rate, secondaryOutcomes measure: Peri operative Complication Rate, secondaryOutcomes measure: Number of cases of Fluid deficits, secondaryOutcomes measure: Operative room turnover time in Full Draping, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Emory Hospital, city: Atlanta, state: Georgia, zip: 30322, country: United States, geoPoint lat: 33.749, lon: -84.38798, locations facility: Emory Dunwoody Clinic, city: Atlanta, state: Georgia, zip: 30338, country: United States, geoPoint lat: 33.749, lon: -84.38798, locations facility: Emory Saint Joseph's Hospital, city: Atlanta, state: Georgia, zip: 30342, country: United States, geoPoint lat: 33.749, lon: -84.38798, hasResults: False
protocolSection identificationModule nctId: NCT06379815, orgStudyIdInfo id: EMRL-23-03, briefTitle: Effect of Oral Lactate Ingestion on Appetite Regulation, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2024-08, completionDateStruct date: 2024-08, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Wilfrid Laurier University, class: OTHER, collaborators name: Natural Sciences and Engineering Research Council, Canada, descriptionModule briefSummary: The goal if this study is to determine how oral lactate ingestion affects markers of appetite regulation. Researchers will compare oral lactate ingestion to a sodium chloride placebo. Participants will consume the lactate or placebo solution and then have blood samples and assessments of appetite over the course of 90 min. Free-living energy intake will be measured for 3 days surrounding each experimental session., conditionsModule conditions: Appetitive Behavior, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: Participants will consume a sodium lactate and sodium chloride placebo in a double-blind, crossover design., primaryPurpose: BASIC_SCIENCE, maskingInfo masking: TRIPLE, maskingDescription: The allocation of lactate and placebo will be completed by a researcher not involved in data collection. Both the participant and the researchers collecting and analyzing the data will be blinded to the treatment allocation. This will be completed in a counter-balanced order., whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 12, type: ESTIMATED, armsInterventionsModule interventions name: Sodium Lactate, interventions name: Sodium Chloride, outcomesModule primaryOutcomes measure: Blood Lactate, primaryOutcomes measure: Acylated ghrelin, primaryOutcomes measure: Total ghrelin, secondaryOutcomes measure: Subjective appetite perception, secondaryOutcomes measure: Free-living energy intake, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 35 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06379776, orgStudyIdInfo id: LabForSIMS-LC1, briefTitle: 3D Model - Classification of Thoracic and Lumbar Spinal Fractures., statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-25, primaryCompletionDateStruct date: 2026-09-30, completionDateStruct date: 2026-09-30, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Université Paris-Sud, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to evaluate and compare the effectiveness of a 3D interactive model versus traditional teaching methods in enhancing the teaching of thoracic and lumbar spine fractures classification (AO Spine) among orthopedic residents.The main questions this study aims to answer are:Does the use of a 3D interactive model improve residents' knowledge regarding the AO Spine classification of spine fractures compared to traditional teaching methods? To what extent does the utilization of a 3D interactive model enhance understanding of spinal anatomy, injury mechanisms, pathophysiology, and fracture diagnosis among surgical residents?Participants will be randomly assigned to either:Group A: Access to the 3D interactive model depicting thoracic and lumbar spine fractures based on the AO Spine classification. They can explore fractures, access textual information, and anatomical annotations.Group B: Traditional teaching materials including slides, texts, and diagrams illustrating spine fractures according to the AO Spine classification.Researchers will compare the post-training knowledge and confidence levels in managing spine fractures between the two groups to assess the efficacy of the 3D model.Participants will be required to fill out pre- and post-training questionnaires assessing their knowledge, experience with 3D educational tools, confidence levels in managing spine fractures, and satisfaction with the teaching method.The study aims to ascertain if the use of the 3D model significantly enhances residents' comprehension of spine fractures compared to conventional teaching methods within the orthopedic curriculum., conditionsModule conditions: Lumbar Spine Disease, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Education through a 3D model, interventions name: Education through a traditional pedagogical support, outcomesModule primaryOutcomes measure: Specific Questionnaire, secondaryOutcomes measure: Objective Structured Assessment of Technical Skills (OSATS), secondaryOutcomes measure: Subjective questionnaire, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06379737, orgStudyIdInfo id: 359n/AO/23, secondaryIdInfos id: MASI_CARIVARI21_01, type: OTHER_GRANT, domain: Fondazione Cariparo, briefTitle: Multi-systemic Rehabilitative Interventions in Long COVID-19 Patients in Two Different Settings: a Randomized Controlled Trial, acronym: MULTI-COVID, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-01-01, primaryCompletionDateStruct date: 2023-12-20, completionDateStruct date: 2023-12-20, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Padua University General Hospital, class: OTHER, descriptionModule briefSummary: Objective: This study aimed to evaluate the effectiveness of a multisystem rehabilitation program for Long Covid patients in two different settings.Design: Randomized controlled trial. Settings: Health resort and home-based. Participants: 72 Long Covid patients. Interventions: Patients were randomly assigned into two groups: Group A (n=36) received health resort intervention, and Group B (n=36) received home-based care. Both groups underwent a 5-week rehabilitation program, involving motor, respiratory, and cognitive exercises, two sessions per week.Outcomes: Assessments were conducted before (T0) and after treatment (T1), at 3 (T2) and 6 months (T3), including respiratory and physical function, handgrip strength, fatigue, pain, quality of life, psychological function, and satisfaction., conditionsModule conditions: Long COVID, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: INVESTIGATOR, enrollmentInfo count: 72, type: ACTUAL, armsInterventionsModule interventions name: Multi-systemic Rehabilitation, outcomesModule primaryOutcomes measure: Numerical Rating Scale (NRS), primaryOutcomes measure: Hand grip strength, primaryOutcomes measure: Barthel Dyspnea Scale, primaryOutcomes measure: Fatigue Assessment Scale, primaryOutcomes measure: Beck's Depression Inventory (BDI, primaryOutcomes measure: Beck Anxiety Inventory (BAI), primaryOutcomes measure: 12-Item Short Form Health Survey (SF-12), secondaryOutcomes measure: Patients satisfaction, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Universityof Padua, city: Padova, zip: 35128, country: Italy, geoPoint lat: 45.40797, lon: 11.88586, hasResults: False
protocolSection identificationModule nctId: NCT06379724, orgStudyIdInfo id: 150349, briefTitle: Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin Graft, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06, primaryCompletionDateStruct date: 2026-12, completionDateStruct date: 2026-12, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: University of Kansas Medical Center, class: OTHER, descriptionModule briefSummary: Investigators hypothesize that topical tranexamic acid will have better or comparable efficacy to topical thrombin in reducing hematoma formation at the wound base. The purpose of the study is to demonstrate that topical tranexamic acid will be a non-inferior alternative medication to the current standard of care,THROMBIN-JMI®, and at a lower cost to the health system., conditionsModule conditions: Burns, conditions: Skin Graft Complications, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Prospective, randomized, blinded, non-inferiority study, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: Subjects will be blinded to their randomization group. Study subject number will be linked to their randomization group. Blinding may be broken if the subject experiences an adverse reaction to the medication utilized for their group so that they are aware that they cannot receive the medication in the future. The research coordinator will have the code to the blind. The surgical team will not be blinded as the overall consistency of the topical agents will differ and may be apparent., whoMasked: PARTICIPANT, enrollmentInfo count: 62, type: ESTIMATED, armsInterventionsModule interventions name: Tranexamic acid, interventions name: Thrombin JMI, interventions name: skin graft, outcomesModule primaryOutcomes measure: The number of participants with hematoma occurrence, primaryOutcomes measure: The rate of percentage of graft take adherence amongst participants, primaryOutcomes measure: Comparison of number of participants that require re-operation, secondaryOutcomes measure: Difference in cost between two hemostatic agents, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06379711, orgStudyIdInfo id: H22-03727, briefTitle: Cardiopulmonary Changes Following Spinal Cord Stimulation in Individuals With Spinal Cord Injury, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-08-01, primaryCompletionDateStruct date: 2028-08-01, completionDateStruct date: 2028-08-01, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: University of British Columbia, class: OTHER, descriptionModule briefSummary: The aim of this study is to examine the mechanisms of transcutaneous spinal cord stimulation (tSCS) for improving cardiovascular and pulmonary function in individuals with chronic motor-complete spinal cord injury (SCI) by measuring vascular related endothelial biomarkers, plasma catecholamines, and respiratory parameters., conditionsModule conditions: Spinal Cord Injuries, conditions: Cardiovascular Diseases, conditions: Cardiopulmonary Diseases, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: Pre-Post Study, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 22, type: ESTIMATED, armsInterventionsModule interventions name: Transcutaneous Spinal Cord Stimulation (tSCS), outcomesModule primaryOutcomes measure: Circulating endothelial biomarkers in EMV/µL (Park et al., 2023), secondaryOutcomes measure: Plasma catecholamines in nmol/L (Claydon & Krassioukov, 2008), secondaryOutcomes measure: Spirometric parameters for lung volume in ml/kg (Aung et al., 2019) for FVC, secondaryOutcomes measure: Spirometric parameters for lung volume in ml/kg (Aung et al., 2019) for FEV1, eligibilityModule sex: ALL, minimumAge: 19 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Blusson Spinal Cord Centre, city: Vancouver, state: British Columbia, zip: V5Z 1M9, country: Canada, geoPoint lat: 49.24966, lon: -123.11934, hasResults: False
protocolSection identificationModule nctId: NCT06379698, orgStudyIdInfo id: CHUBX 2023/78, briefTitle: Rein 3D PRINT PERSONALIZE, acronym: R3DP-P, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-15, primaryCompletionDateStruct date: 2027-06-15, completionDateStruct date: 2027-06-15, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: University Hospital, Bordeaux, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to compare preoperative information and patient experience using a personalized versus a generic 3D printed models of patients' tumoral kidney before and after nephron-sparing surgery. The main outcome measure will be based on semi-structured interviews with the patient and the carers., conditionsModule conditions: Tumoral Kidney, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 90, type: ESTIMATED, armsInterventionsModule interventions name: personalized 3D model pré-opérative education, interventions name: generic 3D model pré-opérative education, outcomesModule primaryOutcomes measure: Qualitative assessment of patient experience 1, primaryOutcomes measure: Qualitative assessment of patient experience 2, primaryOutcomes measure: Qualitative assessment of patient experience 3, secondaryOutcomes measure: Description of interactions between carers and patients, secondaryOutcomes measure: Comparison of the evolution and frequency of terms used by patients in the 2 groups during their care., secondaryOutcomes measure: Studying the use of the 3D-printed kidney model introduced during the medical information consultation up to the post-operative visit by describing the life of the model throughout the entire care process, secondaryOutcomes measure: To study the level of understanding of renal anatomy and surgical issues according to the type of tool (personalized vs generic 3D printed model), secondaryOutcomes measure: Comparison of the level of health literacy between the two groups at different times with changes in the average score on the literacy questionnaire (HLSEU-Q16: European Health Literacy Survey Questionnaire), secondaryOutcomes measure: Description of the changes perceived by carers in patients management in both group, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: CHU de Bordeaux, city: Bordeaux, country: France, contacts name: Gaëlle MARGUE, Docteur, role: CONTACT, geoPoint lat: 44.84044, lon: -0.5805, hasResults: False
protocolSection identificationModule nctId: NCT06379685, orgStudyIdInfo id: SOPH190-0923/I, briefTitle: Study to Evaluate the Safety and Tolerability of PRO-190 Ophthalmic Solution Compared to Systane Ultra® on the Ocular Surface., statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09-30, primaryCompletionDateStruct date: 2025-04-30, completionDateStruct date: 2025-04-30, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Laboratorios Sophia S.A de C.V., class: INDUSTRY, descriptionModule briefSummary: This is a phase I clinical study to evaluate the safety and tolerability of PRO-190 ophthalmic solution through the incidence of unexpected adverse events, changes in Best Corrected Visual Acuity (BCVA), changes in ocular surface integrity, changes in the ocular comfort index (OCI) score, and IOP measurement compared to Systane Ultra®., conditionsModule conditions: Dry Eye, conditions: Dry Eyes Chronic, conditions: Dry Eye Syndromes, designModule studyType: INTERVENTIONAL, phases: PHASE1, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Phase I, controlled, comparative, controlled, comparative., primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: Single-blind, whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 32, type: ESTIMATED, armsInterventionsModule interventions name: PRO-190, interventions name: Systane Ultra®, outcomesModule primaryOutcomes measure: Incidence Unexpected Related Adverse Reactions, secondaryOutcomes measure: Changes in the ocular comfort index (OCI) score in between interventions, secondaryOutcomes measure: Changes in Best Corrected Visual Acuity (BCVA), secondaryOutcomes measure: Changes in tear film breakup time, secondaryOutcomes measure: Changes in intraocular pressure (IOP), secondaryOutcomes measure: Changes in the integrity of the ocular surface (fluorescein staining), secondaryOutcomes measure: Changes in lissamine green staining, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06379672, orgStudyIdInfo id: 2023[No.193], briefTitle: Resonance Breathing Training for Long Covid-related Myocardial Injury, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-25, primaryCompletionDateStruct date: 2024-08-25, completionDateStruct date: 2024-09-05, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Chengdu Sport University, class: OTHER, descriptionModule briefSummary: An investigation of the efficacy of resonance breathing training in the rehabilitation of patients with Long covid-related myocardial injury, conditionsModule conditions: Long COVID, conditions: Myocardial Injury, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 70, type: ESTIMATED, armsInterventionsModule interventions name: Resonance breathing, outcomesModule primaryOutcomes measure: New YorkHeart Association (NYHA), primaryOutcomes measure: left ventricle global longitudinal strain, LVGLS, secondaryOutcomes measure: hypertension, secondaryOutcomes measure: Average heart rate, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06379646, orgStudyIdInfo id: YTS109-003, briefTitle: An Clinical Study of YTS109 Cell Injection in Subjects With Recurrent/Refractory Autoimmune Disease, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-22, primaryCompletionDateStruct date: 2025-04-21, completionDateStruct date: 2026-04-21, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: China Immunotech (Beijing) Biotechnology Co., Ltd., class: INDUSTRY, collaborators name: Shanghai Changzheng Hospital, descriptionModule briefSummary: An exploratory clinical study of the safety and efficacy of YTS109 cell injection in subjects with recurrent/refractory autoimmune disease, conditionsModule conditions: Systemic Lupus Erythematosus, conditions: Systemic Sclerosis, conditions: Inflammatory Myopathy, conditions: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, conditions: Antiphospholipid Syndrome, conditions: Sjogren's Syndrome, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 6, type: ESTIMATED, armsInterventionsModule interventions name: YTS109, outcomesModule primaryOutcomes measure: Safety outcomes, primaryOutcomes measure: Efficacy outcomes for SLE, primaryOutcomes measure: Efficacy outcomes for Sjogren's Syndrome, primaryOutcomes measure: Efficacy outcomes for Systemic Sclerosis, primaryOutcomes measure: Efficacy outcomes for Inflammatory Myopathy, primaryOutcomes measure: Efficacy outcomes for Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, primaryOutcomes measure: Efficacy outcomes for Antiphospholipid Syndrome, secondaryOutcomes measure: Peak Plasma Concentration (Cmax) of YTS109, secondaryOutcomes measure: Time to Peak (Tmax) of YTS109, secondaryOutcomes measure: Area under the plasma concentration versus time curve (AUC) of YTS109, secondaryOutcomes measure: PD parameters, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False