hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06266559, orgStudyIdInfo id: 202101896A3, briefTitle: Efficacy Evaluation of Chang Geng Healthy Drink on Patients With Non-alcoholic Fatty Liver Disease, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-02-15, primaryCompletionDateStruct date: 2024-03-20, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: Chang Gung Memorial Hospital, class: OTHER, descriptionModule briefSummary: For non-alcoholic fatty liver disease, there is currently no effective treatment options. Traditional Chinese medicine (TCM) has a long history of treating liver diseases. However, TCM treatment methods are diverse, and there is currently a lack of high-quality clinical research to confirm the efficacy of Chinese herbal medicine. Thereafter, Chang-Gung Healthy Drink which is a TCM based healthy drink may be used to alleviate the clinical adverse event of non-alcoholic fatty liver disease patients., conditionsModule conditions: Non-Alcoholic Fatty Liver Disease, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Chang Geng Healthy Drink, outcomesModule primaryOutcomes measure: Fatigue Visual Analogue Scale - Current fatigue level, primaryOutcomes measure: Fatigue Visual Analogue Scale - Other daily specific task fatigue level, primaryOutcomes measure: Laboratory Data (Linver Function Index), primaryOutcomes measure: Liver stiffness measurement (kPa), primaryOutcomes measure: Controlled attenuation parameter (dB/m), secondaryOutcomes measure: Number of Participants With Clinical Significant Adverse Avent (Safety Measures), eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06266546, orgStudyIdInfo id: CRYOTXA, briefTitle: Prophylactic Endobronchial Tranexamic Acid to Reduce Bleeding in Transbronchial Cryobiopsy, acronym: CRYOTXA, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2025-03-01, completionDateStruct date: 2025-03-01, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-03-26, sponsorCollaboratorsModule leadSponsor name: Ascension Via Christi Hospitals Wichita, Inc., class: OTHER, descriptionModule briefSummary: Transbronchial cryobiopsies are common procedures used to obtain tissue samples from airways for diagnostic purposes. While these procedures are safe, there is a risk of bleeding from the biopsy site. We are conducting a research study to assess the safety and effectiveness of using tranexamic acid prior to undergoing a transbronchial cryobiopsy., conditionsModule conditions: Hemorrhage Lung, conditions: Endobronchial Mass, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: NON_RANDOMIZED, interventionModel: SINGLE_GROUP, interventionModelDescription: The study will be a prospective, single-arm, non-randomized trial, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Tranexamic acid, outcomesModule primaryOutcomes measure: Major Hemorrhage, secondaryOutcomes measure: Early termination of the procedure due to bleeding, secondaryOutcomes measure: Rate of intermediate hemorrhage, secondaryOutcomes measure: Rate of minor hemorrhage, secondaryOutcomes measure: Inadequate tissue sampling due to bleeding, secondaryOutcomes measure: Graded use of other measures to control bleeding (not prophylactic), secondaryOutcomes measure: Unplanned hospital admission for bleeding complications, secondaryOutcomes measure: Acute cardiovascular side effects, secondaryOutcomes measure: All cause 28 day mortality, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ascension Via Christi, city: Wichita, state: Kansas, zip: 67214, country: United States, geoPoint lat: 37.69224, lon: -97.33754, hasResults: False
protocolSection identificationModule nctId: NCT06266533, orgStudyIdInfo id: Pro2023002473, briefTitle: Dismantling the U.S. Social Norm of the "Kids' Food" Archetype (REACH Project), statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-21, primaryCompletionDateStruct date: 2024-07-01, completionDateStruct date: 2024-07-01, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Rutgers, The State University of New Jersey, class: OTHER, descriptionModule briefSummary: This project is the first stage of a health promotion campaign to shift social norms about marketing and feeding children ultra-processed foods. Embedded within a longitudinal ethnographic study using photo-elicitation techniques, mothers of preschool-age children will be randomly assigned to arts-based or traditional education about ultra-processed food., conditionsModule conditions: Food Selection, conditions: Environmental Exposure, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Participants will be randomly assigned to a conventional nutrition education or an arts-based education group., primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 38, type: ESTIMATED, armsInterventionsModule interventions name: Conventional Ultra-processed Food Nutrition Education, interventions name: Arts-based Ultra-processed Food Nutrition Education, outcomesModule primaryOutcomes measure: Ultra-Processed Food Knowledge, primaryOutcomes measure: Environmental assessment of ultra-processed food, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 85 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Leaguers Inc. Head Start, status: RECRUITING, city: Newark, state: New Jersey, zip: 07102, country: United States, contacts name: Aurthur Nabi, role: CONTACT, phone: 973-643-0300, email: "arthuarthur_nabi@theleaguers.org, geoPoint lat: 40.73566, lon: -74.17237, hasResults: False
protocolSection identificationModule nctId: NCT06266520, orgStudyIdInfo id: DongyangH, briefTitle: MNK Therapy in Releasing the Superficial Fascia for Patients With AAS: an Assessor-blinded, Randomised Controlled Trial, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-01-01, primaryCompletionDateStruct date: 2025-06-01, completionDateStruct date: 2025-06-01, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: Sen-wei Lu, class: OTHER, descriptionModule briefSummary: The goal of this type of randomized controlled trial, employing a blinded evaluator methodology, to verify the clinical efficacy and safety of MNK therapy. This aims to provide a reference for clinical practitioners and AAS patients in their decision-making process.Participants will randomly allocated into two groups using a random number table method, with forty patients in each group. The experimental group (Group 1) underwent MNK therapy to release the superficial fascia, while the control group (Group 2) received conventional acupuncture treatment., conditionsModule conditions: Acute Ankle Sprain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: MNK therapy to release the superficial fascia, interventions name: acupuncture, outcomesModule primaryOutcomes measure: Visual Analogue Scale (VAS), primaryOutcomes measure: Kofoed Ankle Score, eligibilityModule sex: ALL, minimumAge: 16 Years, maximumAge: 55 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: The Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, China, status: RECRUITING, city: Dongyang, state: Zhejiang, zip: 322100, country: China, contacts name: Sen-wei Lu, Dr., role: CONTACT, phone: +8613989441117, email: lswlsw1121@163.com, geoPoint lat: 29.26778, lon: 120.22528, hasResults: False
protocolSection identificationModule nctId: NCT06266507, orgStudyIdInfo id: 169, briefTitle: Examining the Effect of Occupational Therapy-Based Parent Coaching on Feeding Problems in Children With a Preterm Birth, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-02-15, primaryCompletionDateStruct date: 2025-02-15, completionDateStruct date: 2025-03-15, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: Ankara Medipol University, class: OTHER, descriptionModule briefSummary: Feeding problems are common in children with a history of premature birth, and these problems continue into early childhood. Feeding problems are affected by many biopsychosocial factors, and the context in which feeding takes place and the attitudes and behaviors of parents can also be effective in the emergence or continuation of these problems. The aim of our study is to evaluate the effects of occupational therapy-based parent coaching intervention on mothers and their children, who are considered to be primarily responsible for the feeding of children in our country. 46 mothers with premature children will be included in our study and participants will be randomly assigned to intervention/control groups. Mothers will fill out a sociodemographic information form, Behavioral Pediatric Feeding Assessment Scale, Sensory Profile Questionnaire - Oral Sensory Processing Subtest, Family Feeding Strategies Scale and Parental Self-Efficacy Scale via Google forms. Mothers in the research group will be given online occupational therapy-based parent coaching training for 10 weeks. Second evaluations will be carried out after the training; Final evaluations will be applied after 1 month of follow-up., conditionsModule conditions: Feeding Behavior, conditions: Mother-Child Relations, conditions: Feeding and Eating Disorders, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 46, type: ESTIMATED, armsInterventionsModule interventions name: Ergotherapy Based Parent Coaching, interventions name: Informative Brochure Distribution, outcomesModule primaryOutcomes measure: Behavioral Pediatric Feeding Assessment Scale, primaryOutcomes measure: Sensory Profile Questionnaire - Oral Sensory Processing Test, secondaryOutcomes measure: Feeding Strategies Quesstionnaire, secondaryOutcomes measure: Parental Self-Efficacy Scale, eligibilityModule sex: FEMALE, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ankara Medipol University, city: Ankara, state: Ankara/ Altındağ, zip: 06110, country: Turkey, geoPoint lat: 39.91987, lon: 32.85427, hasResults: False
protocolSection identificationModule nctId: NCT06266481, orgStudyIdInfo id: pua04202312313157, briefTitle: Topical Dexamethasone Versus Topical Lidocaine Spray to Reduce POST in Shoulder Arthroscopic Surgeries: A Comparative Study, acronym: post, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-04-30, completionDateStruct date: 2024-05-30, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: Pharos University in Alexandria, class: OTHER, descriptionModule briefSummary: postoperative sore throat is the most frequent side effects after anaesthesia intubation. Dexamethasone and 10% lidocaine spray used prior to surgery has shown useful in managing these complications at the moment. In order to examine the prophylactic impact of local Dexamethasone and lidocaine on postoperative sore throat, this study was conducted., conditionsModule conditions: Postoperative Sore Throat, designModule studyType: INTERVENTIONAL, phases: PHASE2, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Topical dexamethasone, interventions name: 10% lidocaine was sprayed over the tube for the second group, outcomesModule primaryOutcomes measure: Topical dexamethasone versus topical lidocaine spray to reduce post-intubation sore throat in shoulder arthroscopic surgeries: A comparative study, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 50 Years, stdAges: ADULT, contactsLocationsModule locations facility: Pharos University, status: RECRUITING, city: Alexandria, zip: 21348, country: Egypt, contacts name: mona el. massoud, ph anesthesia, role: CONTACT, phone: 002+01005542232, email: mona.elsaid@pua.edu.eg, contacts name: hatem a. attalla, ph anaesthesia, role: CONTACT, phone: 002+1001445568, email: hatattalla@hotmail.com, contacts name: mona el. massoud, lecture, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 31.21564, lon: 29.95527, hasResults: False
protocolSection identificationModule nctId: NCT06266442, orgStudyIdInfo id: Mav-WGS, briefTitle: M. Avium WGS During Mav-PD Treatment, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02, primaryCompletionDateStruct date: 2026-09, completionDateStruct date: 2026-09, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: University Health Network, Toronto, class: OTHER, collaborators name: Western University, Canada, collaborators name: Public Health Ontario Laboratory, Canada, descriptionModule briefSummary: This is a prospective observational study using whole genome sequencing (WGS) to investigate whether new strains (other than the initially identified strain(s)) of M. avium are responsible for persistently culture positive sputum during treatment (refractory disease), or the reversion to culture positive sputum after prior conversion to negative. The study will further investigate for differences between participants living in the Toronto/York region versus participants living elsewhere.The primary goal of this prospective observational study is to understand why some patients with M. avium lung disease have persistent or recurrent M. avium in their sputum despite treatment. The aim is to understand whether it is usually due to treatment failure or new infection., conditionsModule conditions: Mycobacterium Avium, conditions: Mycobacterium Infections, Nontuberculous, conditions: Mycobacterium Infections, conditions: Nontuberculous Mycobacterial Lung Disease, conditions: Respiratory Tract Diseases, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: Whole genome sequencing testing, outcomesModule primaryOutcomes measure: Proportion of patients with persistent culture-positive sputum despite antimicrobial therapy, secondaryOutcomes measure: Whether patients with Mav-PD have evidence of polyclonal infection as demonstrated by the presence of >1 strain of M. avium in the pre-treatment sputum or a sputum sample during treatment, secondaryOutcomes measure: Whether there is a source of infection from the home water environment, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University Health Network, status: RECRUITING, city: Toronto, state: Ontario, zip: M5G, country: Canada, contacts name: Matty Mehrabi, B.Sc. M. Ed, role: CONTACT, phone: 416-603-5726, email: matty.mehrabi@uhn.ca, contacts name: Theodore Marras, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 43.70011, lon: -79.4163, hasResults: False
protocolSection identificationModule nctId: NCT06266429, orgStudyIdInfo id: STUDY00001304, briefTitle: Metabolomic Profiling of Racial Disparity, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2026-12-31, completionDateStruct date: 2026-12-31, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-02-20, sponsorCollaboratorsModule leadSponsor name: Olubukola Nafiu, class: OTHER, descriptionModule briefSummary: Tonsillectomy ± adenoidectomy (T\&A) is one of the most common surgical operations with over 500,000 pediatric T\&As performed annually in the United States. Unfortunately, despite advances in anesthetic and surgical techniques, moderate-severe post-tonsillectomy pain (PTP) remains a significant problem affecting up to 62% of children. PTP is thought to arise from pharyngeal mucosal inflammation, which produces local nerve irritation and pharyngeal muscle spasm. Patient factors and surgical techniques also play major roles. Race is an important phenotypic risk factor for moderately severe early PTP. The underlying molecular basis of this differential pain experience is presently unknown. This gap in knowledge means that therapies are poorly targeted and often unsuccessful. Indeed, treatment options for PTP have not advanced substantively for many years. Metabolomics provides novel opportunities to investigate common and unique "metabolic signature" of PTP through the analysis of low molecular weight compounds produced in response to tissue injury. Therefore, the central themes of this proposal are that (1) PTP is a complex process that may be determined by molecular level factors such as preoperative systemic inflammation and metabolic profile, and (2) these molecular level factors may explain the excess burden of PTP among minority children. Here the investigators seek to utilize a combined clinical, biological and untargeted metabolomics approach to identify candidate small and large serum molecules that may influence the frequency and severity of PTP in children across racial groups. This approach to exploring the molecular basis of PTP is novel and knowledge from the study should substantially enhance understanding of the mechanisms underlying pediatric PTP - and narrow the racial disparities in post-operative pain., conditionsModule conditions: Adenoid Hypertrophy, conditions: Tonsillar Hypertrophy, conditions: Surgery, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Blood collection, outcomesModule primaryOutcomes measure: Mean fold-change of metabolomics markers by race using untargeted reverse-phase liquid-chromatographic mass spectrometry, primaryOutcomes measure: Highest pain score, primaryOutcomes measure: Last pain score, eligibilityModule sex: ALL, minimumAge: 4 Years, maximumAge: 17 Years, stdAges: CHILD, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06266416, orgStudyIdInfo id: 115207, briefTitle: IMARA for Black Male Caregivers and Girls Empowerment (IMAGE), acronym: IMAGE, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-25, primaryCompletionDateStruct date: 2027-05-31, completionDateStruct date: 2028-05-31, studyFirstPostDateStruct date: 2024-02-20, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: University of Illinois at Chicago, class: OTHER, collaborators name: University of Michigan, descriptionModule briefSummary: The scientific premise of this research is that individual, interpersonal, and structural factors impact Black girls' sexual reproductive health outcomes (sexually transmitted infection (STI) and Human Immunodeficiency Virus (HIV)) and experience of sexual violence. This study expands STI/HIV prevention programs to include Black male caregivers, a potentially valuable yet underutilized resource to protect Black girls and reduce their exposure to STI/HIV and sexual violence., conditionsModule conditions: Sexually Transmitted Infections (Not HIV or Hepatitis), conditions: HIV Infections, conditions: Sexual Behavior, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: This study will evaluate the efficacy of IMAGE with 14-18-year-old Black girls (n=300) and male caregivers (n=300) in a 2-arm individually randomized controlled trial. The researchers will compare SRH outcomes (STI incidence, self-reported sexual behavior) at 6- and 12-months among girls randomized to IMAGE or a time-matched general health promotion control program (FUEL).The researchers will simultaneously evaluate implementation determinants (barriers, facilitators, constraints) and processes at Community Based Organizations working through the 3 steps of the implementation model (Prepare, Roll out, and Sustain)., primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: SINGLE, whoMasked: INVESTIGATOR, enrollmentInfo count: 612, type: ESTIMATED, armsInterventionsModule interventions name: IMARA for Black Male Caregivers and Girls Empowerment, interventions name: Time-matched control program, outcomesModule primaryOutcomes measure: STI Incidence in Participants, secondaryOutcomes measure: Rate of STI History among Participants, secondaryOutcomes measure: Number of Participants Using Condoms, secondaryOutcomes measure: Number of Sexual Partners of Participants, eligibilityModule sex: ALL, minimumAge: 14 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Illinois Chicago, city: Chicago, state: Illinois, zip: 60612, country: United States, contacts name: LIsa Sharp, PhD, role: CONTACT, phone: 312-966-1819, email: sharpl@uic.edu, contacts name: Sue Littau, role: CONTACT, phone: 312.996.3932, email: slittau@uic.edu, geoPoint lat: 41.85003, lon: -87.65005, hasResults: False