protocolSection identificationModule nctId: NCT06296849, orgStudyIdInfo id: 00007344, briefTitle: Dyadic Financial Incentive Treatments for Dual Smoker Couples, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-18, primaryCompletionDateStruct date: 2028-05, completionDateStruct date: 2028-05, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: University of Georgia, class: OTHER, collaborators name: McMaster University, collaborators name: University of Kentucky, descriptionModule briefSummary: Smokers partnered with other smokers (i.e., dual-smoker couples) represent \~2/3 of all smokers. Dual-smoker couples (DSCs) are less likely to try to quit smoking and more likely to relapse during a quit attempt, reducing overall smoking cessation rates and representing a high-risk clinical population. Despite their high prevalence and risk for persistent smoking, however, there are limited data on smoking cessation interventions among DSCs. Building on previous research that suggests a) financial incentive treatments (FITs) are effective at increasing quit rates and b) dyadic adaptations of FITs are feasible for implementation in DSCs, the proposed study will systematically two versions of FITs to enhance smoking cessation among DSCs. In addition to determining the efficacy of these dyadic FITs for smoking abstinence in DSCs, the investigators will consider the cost and cost effectiveness of each adaptation as well as mechanisms of change to inform future implementation research. The investigators will additionally consider secondary outcomes including abstinence during treatment and long-term abstinence maintenance after end of treatment.The investigators will address these questions in a three-group randomized controlled trial (RCT). In all conditions, individuals who have smoking partners (i.e., targets) will receive usual care (combination fast and slow acting Nicotine Replacement Therapy + quitting resources). In two conditions, participants will receive incentives for abstinence at three time points (1, 3, and 6 months post-baseline). In the SFIT condition, only the target in a couple will be offered incentives; in the DFIT condition, both target and partner will be offered incentives. Primary efficacy outcome is % point-prevalence abstinence at 6 months post-baseline among targets. Secondary outcomes are point-prevalence abstinence at 1 and 3 months during the treatment and 6 months post-treatment (12-months post-baseline), as well as partner outcomes. The investigators will evaluate possible mechanisms of change including partner support and individual and partner motivation to quit as well as evaluate the cost and relative cost of each abstainer within and across condition. These data on the efficacy, mechanisms, and costs of FITs for DSCs will inform population level implementation and promote successful quitting in this treatment refractory population., conditionsModule conditions: Smoking, Cigarette, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, enrollmentInfo count: 900, type: ESTIMATED, armsInterventionsModule interventions name: Financial Incentive Treatment (FIT), outcomesModule primaryOutcomes measure: Point-Prevalence Abstinence at End of Treatment, secondaryOutcomes measure: Point-Prevalence Abstinence After Treatment, secondaryOutcomes measure: Point-Prevalence Abstinence at First Follow-up, secondaryOutcomes measure: Point-Prevalence Abstinence at Second Follow-up, secondaryOutcomes measure: Partner Point-Prevalence Abstinence, secondaryOutcomes measure: Smoking Heaviness, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Georgia, status: RECRUITING, city: Athens, state: Georgia, zip: 30602, country: United States, contacts name: Michelle R vanDellen, PhD, role: CONTACT, email: mvd@uga.edu, geoPoint lat: 33.96095, lon: -83.37794, hasResults: False