hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06333444, orgStudyIdInfo id: n. 08, 09/03/2021, briefTitle: Counselling Intervention for College Students Experienced Psychological Distress, acronym: TRESPASS, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-01-01, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: University of Campania "Luigi Vanvitelli", class: OTHER, descriptionModule briefSummary: The goal of this clinical trial is to evaluate mental health and academic motivation in university students asking help to university counselling service (UCS) in Southern Italy before anf after four weekly psychological sessions.The main question it aims to answer are:* is the psychological counselling intervention useful in improving psychological distress and academic motivation* which psychological variables predict the intervention outcome, conditionsModule conditions: University Students, conditions: Psychological Intervention, conditions: Psychological Distress, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: Four weekly psychological counselling intervention, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: four weekly psychological counselling intervention, outcomesModule primaryOutcomes measure: psychological distress, primaryOutcomes measure: Academic motivation, secondaryOutcomes measure: Emotion regulation ability, secondaryOutcomes measure: perceived loneliness, secondaryOutcomes measure: drop-out intention, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 30 Years, stdAges: ADULT, contactsLocationsModule locations facility: University of Campania, status: RECRUITING, city: Caserta, zip: 81100, country: Italy, contacts name: ALDA TRONCONE, role: CONTACT, email: alda.troncone@unicampania.it, geoPoint lat: 41.07262, lon: 14.33231, hasResults: False
protocolSection identificationModule nctId: NCT06333431, orgStudyIdInfo id: WN/WF, briefTitle: Effects of WN and WF During Gastroscopy, acronym: WF/WN_GCPY, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-03, primaryCompletionDateStruct date: 2024-05-30, completionDateStruct date: 2024-06-08, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Suleyman Demirel University, class: OTHER, descriptionModule briefSummary: Background: Gastroscopy is an endoscopic procedure that allows examination of the upper gastrointestinal system, including the esophagus, stomach and duodenum. The procedure is a difficult and stressful diagnosis and treatment method for the patient. Problems such as stress, fear and pain experienced during endoscopy cause anxiety.Purpose: To examine effects of glass waterfall and white noise on pain, anxiety and physiological parameters during gastroscopy Method: The population of the study consists of all patients who applied to Mardin Education and Research Hospital, Department of General Surgery, Endoscopy Unit and were scheduled for gastroscopy. The sample will be represented by 156 patients whose gastroscopy procedure is planned between the specified dates and who meet the criteria for inclusion in the sample. In calculating the sample of the study, power analysis was performed and it was found the effect size of 1.16, 95% power and 0.05% margin of error for this study, that a total of 156 individuals for the three groups and at 52 individuals for each group. Before gastroscopy procedure, the patients included in the study will be randomly divided into three groups: 52 glass waterfall group, 52 white noise group and 52 control group., conditionsModule conditions: Misadventure During Endoscopic Examination, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Parallel Assignment experimental model using randomized pretest and posttest with control group, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 156, type: ESTIMATED, armsInterventionsModule interventions name: Glass Waterfall group, interventions name: white noise group, outcomesModule primaryOutcomes measure: Patient Information Form, primaryOutcomes measure: Visual Analogue Scale (VAS), primaryOutcomes measure: State and Trait Anxiety Scale (STAI), primaryOutcomes measure: The Patient Observation Form, primaryOutcomes measure: Pulse rate before and after gatroscopy procedure, primaryOutcomes measure: Respiratory rate before and after gatroscopy procedure, primaryOutcomes measure: Systolic and diastolic blood pressure before and after gatroscopy procedure, primaryOutcomes measure: Oxygen saturation values before and after gatroscopy procedure, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06333405, orgStudyIdInfo id: FMTNEC/01/2024, briefTitle: Fecal Microbiota Transplantation (FMT) as a Prophylaxis of Necrotizing Enterocolitis (NEC) - Clinical Study, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2025-01-31, completionDateStruct date: 2025-01-31, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Medical University of Warsaw, class: OTHER, descriptionModule briefSummary: The aim of the study is to assess the safety of fecal microbiota transplantation (FMT) as a preventive method for the development of Necrotizing enterocolitis (NEC) in a group of premature infants.This is the first stage of a clinical trial testing the effectiveness of FMT in NEC, the aim of which is to examine the safety profile and analyze all side effects., conditionsModule conditions: Necrotizing Enterocolitis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: single group, open label, observational study with intervention (FMT), primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: Fecal Microbiota Transplantation, outcomesModule primaryOutcomes measure: Adverse reactions monitoring, eligibilityModule sex: ALL, minimumAge: 24 Weeks, maximumAge: 36 Weeks, stdAges: CHILD, contactsLocationsModule locations facility: Medical University of Warsaw, Pediatric Surgery Clinic, city: Warsaw, state: Mazovian Voivodeship, zip: 02-097, country: Poland, contacts name: Marek Wolski, MD, PhD, role: CONTACT, phone: 665578922, phoneExt: +48, email: marek.wolski@wum.edu.pl, contacts name: Ewa A. Biegańska, MD, role: CONTACT, phone: 692542543, phoneExt: +48, email: ewa.bieganska@wum.edu.pl, geoPoint lat: 52.22977, lon: 21.01178, hasResults: False
protocolSection identificationModule nctId: NCT06333327, orgStudyIdInfo id: 1432022000278, briefTitle: Multicenter Registry of Atrial Fibrillation Ablation With Radiofrequency Balloon Catheter, acronym: COLLABORATE, statusModule overallStatus: RECRUITING, startDateStruct date: 2021-01-01, primaryCompletionDateStruct date: 2030-01-01, completionDateStruct date: 2030-12-01, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Universitair Ziekenhuis Brussel, class: OTHER, descriptionModule briefSummary: All consecutive patients with paroxysmal or persistent atrial fibrillation undergoing pulmonary vein isolation with the radiofrequency balloon catheter (RFB) "Heliostar" (Biosense Webster) will be included in a multicenter observational registry. The aim of the study is to assess the safety and arrhythmic outcome of atrial fibrillation ablation with the RFB in a real-world setting., conditionsModule conditions: Atrial Fibrillation, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 2000, type: ESTIMATED, armsInterventionsModule interventions name: Pulmonary vein isolation with the multielectrode radiofrequency balloon catheter, outcomesModule primaryOutcomes measure: Atrial arrhythmia recurrence after ablation, primaryOutcomes measure: Procedural safety, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 85 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: UZ Brussel Heart Rhythm Management Center, status: RECRUITING, city: Brussels, zip: 1090, country: Belgium, contacts name: Carlo de Asmundis, MD, PhD, role: CONTACT, phone: +32024763704, email: hrmc@uzbrussel.be, geoPoint lat: 50.85045, lon: 4.34878, hasResults: False
protocolSection identificationModule nctId: NCT06333301, orgStudyIdInfo id: TIME-ZZZ, briefTitle: Translational Initiative to Map Epigenetics in Sleep, acronym: TIME-ZZZ, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2034-04, completionDateStruct date: 2034-04, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Elysium Health, class: INDUSTRY, collaborators name: University of Oxford, descriptionModule briefSummary: The primary aim of TIME-ZZZ is to explore the relationship between chronotype, incidence of depression and biological age, and whether individuals working "out-of-phase" with their chronotype are more likely to exhibit signs of depression and accelerated biological aging., conditionsModule conditions: Biological Aging, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 10000, type: ESTIMATED, armsInterventionsModule interventions name: Surveys, outcomesModule primaryOutcomes measure: Effect of being "out of phase" with chronotype on biological age, secondaryOutcomes measure: Effect of Chronotype Alignment and Depression Risk in Relation to Rate of Aging, secondaryOutcomes measure: Identification of DNA methylation markers associated with chronotype, secondaryOutcomes measure: Identification of DNA methylation markers associated with depression, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06333288, orgStudyIdInfo id: 2024-0268, briefTitle: Pilot Trial to Evaluate PROblem Solving Therapy and APPLE Watch for College Students, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-15, primaryCompletionDateStruct date: 2024-11-30, completionDateStruct date: 2025-03-30, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: University of Illinois at Chicago, class: OTHER, descriptionModule briefSummary: The goals of this Pilot Trial are to test the preliminary efficacy of Problom-Solving Therapy (PST)-APPLE Watch in a 2-arm pilot Randomized Control Trial (RCT), vs education only-control to reduce alcohol use disorder symptoms and improve alcohol abstinence., conditionsModule conditions: Alcohol Use Disorder, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: PRO-APPLE Study is a 2-arm pilot Randomized Control Trial (RCT)., primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 44, type: ESTIMATED, armsInterventionsModule interventions name: PST-APPLE Watch group, interventions name: Education-only control group, outcomesModule primaryOutcomes measure: Alcohol abstinence, secondaryOutcomes measure: Change in AUD severity at 3 months., secondaryOutcomes measure: Change in AUD frequency status., secondaryOutcomes measure: Change in Alcohol-related negative consequences at 3 months., secondaryOutcomes measure: Change in Alcohol use at 3 months., secondaryOutcomes measure: Change in Reasons for drinking at 3 months., secondaryOutcomes measure: Change in negative affect at 3 months., secondaryOutcomes measure: Change in positive affect at 3 months., secondaryOutcomes measure: Change in Cognitive performance (executive cognitive ability and attention and working memory) at 3 months., secondaryOutcomes measure: Change in the quality of life at 3 months., secondaryOutcomes measure: Percent heavy drinking days at 3 months., secondaryOutcomes measure: Percent binge drinking days at 3 months., secondaryOutcomes measure: Percent days abstinence at 3 months., otherOutcomes measure: Intervention Acceptability, otherOutcomes measure: Intervention Fidelity, otherOutcomes measure: Participant Retention, otherOutcomes measure: Protocol Acceptability, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 25 Years, stdAges: ADULT, contactsLocationsModule locations facility: University of Illinois at Chicago, city: Chicago, state: Illinois, zip: 60608, country: United States, contacts name: Hagar Hallihan, role: CONTACT, geoPoint lat: 41.85003, lon: -87.65005, hasResults: False
protocolSection identificationModule nctId: NCT06333262, orgStudyIdInfo id: 24-017, briefTitle: Fixed Duration Pirtobrutinib and Obinutuzumab in Chronic Lymphocytic Leukemia, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2027-02-01, completionDateStruct date: 2029-02-01, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-04-23, sponsorCollaboratorsModule leadSponsor name: Inhye Ahn, class: OTHER, collaborators name: Loxo Oncology, Inc., descriptionModule briefSummary: This study will evaluate fixed-duration therapy with pirtobrutinib and obinutuzumab given over 12 cycles (approximately 1 year) as first-line treatment of chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL or SLL)., conditionsModule conditions: Chronic Lymphocytic Leukemia, conditions: Small Lymphocytic Lymphoma, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: NA, interventionModel: SEQUENTIAL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Pirtobrutinib, interventions name: Obinutuzumab, outcomesModule primaryOutcomes measure: Rate of complete response after initial therapy, secondaryOutcomes measure: Overall response rate, secondaryOutcomes measure: Rate of partial response, secondaryOutcomes measure: Time to next line of therapy, secondaryOutcomes measure: Event-free survival, secondaryOutcomes measure: Progression-free survival, secondaryOutcomes measure: Overall survival, secondaryOutcomes measure: Rate of re-treatment with pirtobrutinib, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Beth Israel Deaconess Medical Center, status: RECRUITING, city: Boston, state: Massachusetts, zip: 02215, country: United States, contacts name: Jon Arnason, MD, role: CONTACT, contacts name: Jon Arnason, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 42.35843, lon: -71.05977, locations facility: Brigham & Women's Hospital, status: RECRUITING, city: Boston, state: Massachusetts, zip: 02215, country: United States, contacts name: Inhye Ahn, role: CONTACT, contacts name: Inhye Ahn, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 42.35843, lon: -71.05977, locations facility: Dana-Farber Cancer Institute, status: RECRUITING, city: Boston, state: Massachusetts, zip: 02215, country: United States, contacts name: Megan Forsyth, role: CONTACT, phone: 857-215-1405, email: megan_forsyth@dfci.harvard.edu, contacts name: Inhye Ahn, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 42.35843, lon: -71.05977, hasResults: False
protocolSection identificationModule nctId: NCT06333236, orgStudyIdInfo id: OCU_KRON, briefTitle: Effect of Kron (Citicoline and Nicotinamide Oral Solution) on Patients With Open-angle Glaucoma, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-25, primaryCompletionDateStruct date: 2024-09-30, completionDateStruct date: 2024-11-30, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: ASST Santi Paolo e Carlo, class: OTHER, descriptionModule briefSummary: Aim of this study is to investigate the administration effects of the combination of citicoline 40mg/ml and nicotinamide 15mg/ml oral solution (Kron®) on short term improvement in inner retinal function, bioelectrical activity of the visual cortex and visual function., conditionsModule conditions: Glaucoma, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Food for Special Medical Purposes: Kron®, outcomesModule primaryOutcomes measure: Electrofunctional evaluation, secondaryOutcomes measure: VF and SD-OCT, eligibilityModule sex: ALL, minimumAge: 40 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06333197, orgStudyIdInfo id: Mandibular condylar fracture, briefTitle: Approaches for Open Reduction and Internal Fixation of Mandibular Condylar Fracture, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-03-01, completionDateStruct date: 2025-07-01, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-28, sponsorCollaboratorsModule leadSponsor name: Assiut University, class: OTHER, descriptionModule briefSummary: The condylar region is the most frequent anatomical site for mandibular fractures .Condylar fractures constitute 25.5% to 35.5% of all mandibular fractures. The mandibular condyle fracture is a type of fracture that affects the condyle, which is the knuckle-like projection of the mandible (lower jaw) that articulates with the temporal bone to form the temporomandibular joint (TMJ)., conditionsModule conditions: Mandibular Fractures, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: ALL Patients diagnosed with Extra Capsular Fracture of Mandibular Condyle amenable for surgery., primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: ORIF through transparotid approach, interventions name: ORIF through retroparotid approach, outcomesModule primaryOutcomes measure: Facial nerve injury, primaryOutcomes measure: Operative time, secondaryOutcomes measure: Fracture stability, secondaryOutcomes measure: Mouth opening, secondaryOutcomes measure: Other Complication related to the Approach, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06333184, orgStudyIdInfo id: 3085-4215, briefTitle: Smoothies and Blood Sugars, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-20, primaryCompletionDateStruct date: 2024-08-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-27, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: University of Bath, class: OTHER, descriptionModule briefSummary: Glycaemic responses to fruit smoothies may depend on the food matrix (e.g., degree of processing and physical structure), ingestion rate, dose ingested and fibre content. Furthermore, the method of sampling could alter inferences. The aim of this project is to characterise how these factors affect the glycaemic response to a commercially available fruit smoothie. Participants will ingest 7 different test drinks in a randomised, crossover design with fingerstick capillary blood sampling alongside continuous glucose monitors. Test drinks will include a glucose reference (CONTROL), the commercial product matched for carbohydrate to CONTROL (PRODUCT), equivalent carbohydrate ingested as whole fruits (WHOLE), equivalent carbohydrate ingested as blended fruits (WHOLE), equivalent carbohydrate as the commercial product ingested slowly (SLOW), equivalent carbohydrate as the commercial product ingested with additional fibre (FIBRE), and the commercial product ingested in a dose typically bought (DOSE). These data will provide insight into how the food matrix and different patterns of ingestion can alter the glycaemic response to a fruit smoothie, and how the measurement method may alter interpretations., conditionsModule conditions: Metabolic Disturbance, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 15, type: ESTIMATED, armsInterventionsModule interventions name: Food, outcomesModule primaryOutcomes measure: Glycaemic index of product with capillary vs CGM, secondaryOutcomes measure: Glycaemic index of all conditions with capillary vs CGM, otherOutcomes measure: Condition-by-sampling interaction, otherOutcomes measure: GI of products in capillary samples, otherOutcomes measure: GI of products in continuous glucose monitors, otherOutcomes measure: Peak glucose capillary vs CGM, otherOutcomes measure: Time to peak glucose capillary vs CGM, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Department for Health, University of Bath, status: RECRUITING, city: Bath, zip: BA2 7AY, country: United Kingdom, contacts name: Javier T Gonzalez, PhD, role: CONTACT, phone: +44 (0) 1225 38, phoneExt: 5125, email: j.t.gonzalez@bath.ac.uk, geoPoint lat: 51.3751, lon: -2.36172, hasResults: False