hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06291597, orgStudyIdInfo id: 22071, briefTitle: Vaping Adverse Lung and Heart Events Cohort, acronym: VapALERT, statusModule overallStatus: RECRUITING, startDateStruct date: 2021-10-14, primaryCompletionDateStruct date: 2031-12, completionDateStruct date: 2032-06, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Laval University, class: OTHER, collaborators name: Ministere de la Sante et des Services Sociaux, descriptionModule briefSummary: This prospective study assesses the pulmonary and cardiovascular effets of vaping in adult electronic cigarette users with biannual visits and a 5-year follow-up., conditionsModule conditions: Vaping, conditions: Electronic Cigarette Use, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 250, type: ESTIMATED, armsInterventionsModule interventions name: Vaping, outcomesModule primaryOutcomes measure: Number of participants who vape daily with impaired lung volumes., primaryOutcomes measure: Number of participants who vape daily with impaired lung diffusion capacity., primaryOutcomes measure: Number of participants who vape daily with impaired spirometry., primaryOutcomes measure: Number of participants who vape daily with airway hyperresponsiveness., primaryOutcomes measure: Number of participants who vape daily with changes in blood cell count., primaryOutcomes measure: Number of participants who vape daily with changes in sputum cell count., primaryOutcomes measure: Vaping, tobacco and cannabis smoking habits of participants., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: IUCPQ-UL, status: RECRUITING, city: Québec, zip: G1V 4G5, country: Canada, contacts name: Ariane Lechasseur, PhD, role: CONTACT, phone: 418-656-8711, phoneExt: 2652, email: ariane.lechasseur@criucpq.ulaval.ca, contacts name: Mathieu C Morissette, PhD, role: PRINCIPAL_INVESTIGATOR, contacts name: Andréanne Côté, MD, MSc, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 46.81228, lon: -71.21454, hasResults: False
protocolSection identificationModule nctId: NCT06291584, orgStudyIdInfo id: P20230001, briefTitle: Effects of Exercises on Functional Capacity, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-10-01, primaryCompletionDateStruct date: 2024-05-01, completionDateStruct date: 2024-10-01, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Kırklareli University, class: OTHER, descriptionModule briefSummary: In this study, the researchers aim to investigate the effects of strengthening and respiratory exercises on the face and online on functional capacity., conditionsModule conditions: Nicotine Addiction, conditions: Respiratory Disease, conditions: Sedentary Behavior, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The study consists of three groups. Groups to be formed: Group 1: face-to-face exercise group; Group 2: Online (Telehealth) Exercise Group; Group 3: Control Group, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: First of all, the randomization of exercise groups will be performed according to the closed envelope procedure. The student who selects one of the envelopes with the names of the three groups will be included in the group written in the envelope he selected., whoMasked: PARTICIPANT, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Exercise, outcomesModule primaryOutcomes measure: International Physical Activity Questionnaire - Short Form, primaryOutcomes measure: Six-Minute Walk Test- (6MWT), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Kirklareli University, status: RECRUITING, city: Kırklareli, state: Kayalı, zip: 39000, country: Turkey, contacts name: Fulya DEMIRHAN, Res. Ass., role: CONTACT, phone: +90-532-353-2208, email: fulyademirhan@klu.edu.tr, geoPoint lat: 41.73508, lon: 27.22521, hasResults: False
protocolSection identificationModule nctId: NCT06291571, orgStudyIdInfo id: 324543, briefTitle: Assessment of Microorganisms and Host Response In Liver Diseases, acronym: MILD, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2029-02-28, completionDateStruct date: 2030-03-01, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: University of Aberdeen, class: OTHER, descriptionModule briefSummary: The normal human gut is home to millions of microbes including bacteria, fungi, and viruses, collectively forming the gut microbiota, which exists in harmony within us. Much research is still required to fully understand the contribution of microbes resident in the large intestine in liver diseases. The liver receives blood from the gut carrying all the necessary nutrients needed for our body but also has to deal with toxins derived from the microbes residing in the intestines. The gut microbiota is altered in liver disease. We still do not know clearly how this change impacts liver function and the health of liver patients. The purpose of our study is to answer this question by assessing the gut microbiota using modern microbiological and molecular methods. By studying the alterations in the gut microbiota in patients with liver disease we can understand how they affect our immune system and metabolism. This will help design novel medicinal products to prevent and treat liver disease., conditionsModule conditions: Gut Microbiome, conditions: Liver Diseases, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule, outcomesModule primaryOutcomes measure: To identify the bacterial, fungal, and virological agents present in patients with liver disease as opposed to controls, secondaryOutcomes measure: To assess the host immune response against specific microbes isolated from patients with liver disease and controls, secondaryOutcomes measure: To characterise the changes in the liver immune microenvironment by analysing liver biopsies from patients, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06291558, orgStudyIdInfo id: P202200027, briefTitle: Exercise Training for Smoking Students, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-10-01, primaryCompletionDateStruct date: 2024-05-01, completionDateStruct date: 2024-10-01, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Kırklareli University, class: OTHER, descriptionModule briefSummary: Smoking can damage lung functions as a result of high carbon monoxide and low hemoglobin oxygen carrying capacity in the blood. Smoking between young people continues to increase, which can cause respiratory function problems and lung diseases at an early age. In the studies, it has been seen that smoking may reduce the oppression and exercise ability., conditionsModule conditions: Nicotine Dependence, conditions: Smoking, conditions: Physical Inactivity, conditions: Depression, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: SINGLE, maskingDescription: The participants will be informed that the study was carried out for scientific purposes and the information will not be shared with third parties. Randomization of exercise groups will be performed according to the closed envelope procedure. The student who selects one of the envelopes with the names of the 3 groups will be included in the group written in the envelope he selected. Information about other groups will not be shared., whoMasked: PARTICIPANT, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Exercise, outcomesModule primaryOutcomes measure: International Physical Activity Questionnaire (Short), primaryOutcomes measure: Six-Minute Walk Test, primaryOutcomes measure: Scoring the Fagerstrom Test for Nicotine Dependence (FTND), primaryOutcomes measure: Beck's Depression Inventory (BDI), primaryOutcomes measure: Lung Function Test, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Kirklareli University, status: RECRUITING, city: Kırklareli, state: Kayalı, zip: 39000, country: Turkey, contacts name: Fulya DEMIRHAN, Res. Ass., role: CONTACT, phone: +90-532-353-2208, email: fulyademirhan@klu.edu.tr, geoPoint lat: 41.73508, lon: 27.22521, hasResults: False
protocolSection identificationModule nctId: NCT06291545, orgStudyIdInfo id: JW-SBC202202, briefTitle: Effectiveness and Safety of Coronary Scoring Balloon Dilation Catheter in the Pretreatment of Coronary Stenosis Lesions, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-20, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2025-06-30, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-05, sponsorCollaboratorsModule leadSponsor name: JW Medical Systems Ltd, class: INDUSTRY, descriptionModule briefSummary: This trial adopts a prospective, multicenter, randomized controlled, and non-inferiority comparison trial design, and plans to recruit 200 eligible subjects who will be randomly assigned to the experimental group or the control group in a 1:1 ratio. All randomly enrolled subjects will be followed up until 30 days after the surgery., conditionsModule conditions: Coronary Artery Disease, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: Coronary artery scoring balloon dilation catheter（JW Medical Systems Ltd）, interventions name: ScoreFlex NC Coronary Dilatation Catheter, outcomesModule primaryOutcomes measure: Rate of successful device usage, secondaryOutcomes measure: Rate of success of the surgery, secondaryOutcomes measure: Incidence of in-hospital MACE, secondaryOutcomes measure: Incidence of PoCE within 30 days after surgery, secondaryOutcomes measure: The lumen is obtained immediately, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06291532, orgStudyIdInfo id: VRRS01, briefTitle: Feasibility and Usability of a Virtual Reality System, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2023-04-01, primaryCompletionDateStruct date: 2025-09-30, completionDateStruct date: 2025-09-30, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: IRCCS Centro Neurolesi "Bonino-Pulejo", class: OTHER, descriptionModule briefSummary: Intellectual disability (ID) and autism spectrum disorder (ASD) are often co-occurring neurodevelopmental disorders that require composite intervention. However, standardized rehabilitation programs presented several limitations due to behavioral problems and poor engagement in proposed activity. The Virtual Reality Rehabilitation System (VRRS) is a medical device is recognized as one of the most advanced systems to rehabilitate patients with motor, cognitive, linguistic and behavioral disorders. The use of VRRS offers the opportunity to adapting task parameters according to the patient's performance and the virtual system increases engagement and avoids boredom and frustration. the patients underwent a two months experimental intervention integrated into the regular activity of a semi-residential center for autistic adolescents and young adults., conditionsModule conditions: Autism Spectrum Disorder, conditions: Intellectual Disability, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Rehabilitation with VRRS, outcomesModule primaryOutcomes measure: Usability questionnaire, primaryOutcomes measure: Virtual Reality Rehabilitation System (VRRS) electromedical device parameters: screen attention time, primaryOutcomes measure: Virtual Reality Rehabilitation System (VRRS) electromedical device parameters: the number of repetitions of the exercises., primaryOutcomes measure: Virtual Reality Rehabilitation System (VRRS) electromedical device parameters:global scores for exercise., eligibilityModule sex: ALL, minimumAge: 6 Years, maximumAge: 40 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: IRCCS Centro Neurolesi Bonino Pulejo, city: Messina, zip: 98124, country: Italy, geoPoint lat: 38.19394, lon: 15.55256, hasResults: False
protocolSection identificationModule nctId: NCT06291519, orgStudyIdInfo id: SHN50343434, briefTitle: The Effect of Multisensory Stimulus Method on Pain and Physiological Parameters in Infants, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-01-01, primaryCompletionDateStruct date: 2023-12-30, completionDateStruct date: 2023-12-30, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Istanbul University - Cerrahpasa (IUC), class: OTHER, descriptionModule briefSummary: This study aimed to investigate the impact of employing the multi-sensory stimulation technique by both the mother and the nurse on the pain and physiological responses of infants aged 2-6 months during vaccination. The significance of pain experienced during vaccination in children is emphasized, potentially leading to avoidance behaviors toward healthcare services. There is growing evidence supporting the efficacy of non-pharmacological interventions. Multi-sensory stimulation, which integrates various stimuli such as taste, touch, and speech, alleviates infant pain. However, there has been a lack of studies assessing the effectiveness of this approach during vaccination administered by different healthcare providers. Hence, this study sought to explore the effects of multi-sensory stimulation by both mother and nurse applied to pain and physiological parameters. It is anticipated that the findings of this study will contribute to both pain management strategies and healthcare practices., conditionsModule conditions: Multisensory Stimulation, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized controlled experimental design, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: NONE, enrollmentInfo count: 96, type: ACTUAL, armsInterventionsModule interventions name: Multi-sensory Stimulation Method-Mother Applying the Method to the Baby, interventions name: Multi-sensory Stimulation Method-Nurse Applying the Method to the Baby, interventions name: Breastfeeding Applied Group, outcomesModule primaryOutcomes measure: The Effect of Multiple Sensory Stimulus Method, secondaryOutcomes measure: Comparison of the group in which the mother applied multiple sensory stimuli and the group in which the nurse applied multiple sensory stimuli, eligibilityModule sex: ALL, minimumAge: 2 Months, maximumAge: 6 Months, stdAges: CHILD, contactsLocationsModule locations facility: Istanbul University-Cerrahpasa, city: Istanbul, state: None Selected, zip: 34381, country: Turkey, geoPoint lat: 41.01384, lon: 28.94966, hasResults: False
protocolSection identificationModule nctId: NCT06291506, orgStudyIdInfo id: 6270, briefTitle: SUbstrate Ablation in Persistent Atrial Fibrillation for Elimination of Recurrences (SUPAFER)., acronym: SUPAFER, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-05-01, primaryCompletionDateStruct date: 2026-05-01, completionDateStruct date: 2026-05-01, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Hospital Universitario La Paz, class: OTHER, descriptionModule briefSummary: Antecedents: electrical isolation of pulmonary veins is the standard treatment for patients with atrial fibrillation. However, its efficacy is lower in persistent and chronic forms of this arrhythmia compared to paroxysmal atrial fibrillation. Many complementary techniques have been proposed, that added to pulmonary veins isolation, may reduce the recurrence rate of atrial fibrillation. However, none of them has obtained consistent results. Linear ablation aims to parcellate and modify the left atrial substrate responsible for atrial fibrillation maintenance. Previous studies have offered contradictory results using linear ablation.Methods: SUPAFER is a multicenter, 1:1 randomized clinical trial that compares the efficacy of pulmonary veins isolation alone vs pulmonary vein isolation plus an specific protocol of left atrial linear ablation. Contrary to previous studies, the specific SUPAFER linear ablation is systematic, homogeneous and target atrial areas that have not been systematically ablated in previous trials. The trial aims at demonstrating the superiority of the combined ablative approach during 1-year follow-up. Daily transtelephonic ECG samples a 30 days continuous ECG monitoring are used to maximize de detection of recurrences, even asymptomatic., conditionsModule conditions: Persistent and Long Lasting or Chronic Atrial Fibrillation, conditions: Atrial Fibrillation Ablation, conditions: Linear Left Atrial Ablation, conditions: Daily Transtelephonic Electrocardiogram, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: 1:1 randomization, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 176, type: ESTIMATED, armsInterventionsModule interventions name: Radiofrequency ablation of heart atrial tissue., outcomesModule primaryOutcomes measure: Recurrences of sustained >30 secons atrial arrhythmias measured by daily ECG samples (Kardia Alivecor) and 30 days continuous Holter., secondaryOutcomes measure: Acute intraprocedure efficacy., secondaryOutcomes measure: Complications., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: La Paz University Hospital - IdiPaz, status: RECRUITING, city: Madrid, country: Spain, contacts name: José Luis Merino, MD, role: CONTACT, phone: +34 912071301, email: lapaz@arritmias.net, contacts name: Sergio Castrejón Castrejón, role: SUB_INVESTIGATOR, geoPoint lat: 40.4165, lon: -3.70256, hasResults: False
protocolSection identificationModule nctId: NCT06291493, orgStudyIdInfo id: CS-2024-0002, briefTitle: Precision Study Measuring Potassium (K) in Capillary Specimens, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06, primaryCompletionDateStruct date: 2024-10, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Abbott Point of Care, class: INDUSTRY, descriptionModule briefSummary: Assessing precision of i-STAT K test using the IUO i-STAT CG8+ cartridge on the i-STAT 1 Analyzer., conditionsModule conditions: Precision of Potassium (K) Test in Capillary Whole Blood, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: Capillary precision analysis will be performed for Potassium K., primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 150, type: ESTIMATED, armsInterventionsModule interventions name: Fingerstick blood draw, outcomesModule primaryOutcomes measure: Precision for Potassium (K) Test, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06291454, orgStudyIdInfo id: 741100, briefTitle: GCF Levels of Chemokines in Periodontitis, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-01-01, primaryCompletionDateStruct date: 2023-12-01, completionDateStruct date: 2023-12-01, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: T.C. ORDU ÜNİVERSİTESİ, class: OTHER, descriptionModule briefSummary: This study aimed to determine CCL19/MIP3beta(β) and CCL20/MIP3alpha(α) in the gingival crevicular fluid (GCF) of the patients with different periodontitis phenotypes.A total of 72 individuals, 24 with Stage III Grade B periodontitis (Group 1), 24 with Stage III Grade C periodontitis (Group 2), and 24 periodontally healthy (control group) (Group 3), were included in the study. GCF and clinical periodontal parameters were obtained at baseline. MIP3β and MIP3α levels in GCF were determined by ELISA., conditionsModule conditions: Periodontal Diseases, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 72, type: ACTUAL, armsInterventionsModule interventions name: Routine periodontal examination, outcomesModule primaryOutcomes measure: CCL19/MIP3beta(β) levels, primaryOutcomes measure: CCL20/MIP3alpha(α) levels, secondaryOutcomes measure: CCL19/MIP3beta(β) levels and clinical parameters, secondaryOutcomes measure: CCL20/MIP3alpha(α) levels and clinical parameters, eligibilityModule sex: ALL, minimumAge: 22 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule locations facility: Ordu University, Faculty of Dentistry, city: Ordu, zip: 52100, country: Turkey, geoPoint lat: 40.97782, lon: 37.89047, hasResults: False
protocolSection identificationModule nctId: NCT06291402, orgStudyIdInfo id: RC 34-1-2024, briefTitle: Nasal Packing Duration and Development of Pharyngitis After Septorhinoplasty Surgery, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-10, primaryCompletionDateStruct date: 2024-06-15, completionDateStruct date: 2024-06-15, studyFirstPostDateStruct date: 2024-03-04, lastUpdatePostDateStruct date: 2024-03-04, sponsorCollaboratorsModule leadSponsor name: Al-Azhar University, class: OTHER, collaborators name: Benha University, descriptionModule briefSummary: Septoplasty or septal reconstruction is a corrective surgical procedure performed to straighten the nasal septum. It may be associated with numerous complications. To minimize these complications, both nasal cavities are frequently packed with different types of nasal packing. In our study we will try to find relationship between duration of nasal packing and postrhinoplasty sore throat and pharyngitis., conditionsModule conditions: Rhinitis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, outcomesModule primaryOutcomes measure: Sore throat, secondaryOutcomes measure: Dysphagia, secondaryOutcomes measure: Throat irritation, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Neveen Kohaf, city: Tanta, zip: 11865, country: Egypt, contacts name: Neveen Kohaf, Ph.D, role: CONTACT, phone: +201060383012, email: nevenabdo@azhar.edu.eg, contacts name: Haney Bauiomy, M.D, role: PRINCIPAL_INVESTIGATOR, contacts name: Ahmed Abosakaya, M.D, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 30.78847, lon: 31.00192, hasResults: False