protocolSection identificationModule nctId: NCT06378112, orgStudyIdInfo id: 2734/CEIH/2022, briefTitle: Extraction Socket Augmentation. A Clinical Study, acronym: GTO, statusModule overallStatus: RECRUITING, startDateStruct date: 2022-05-20, primaryCompletionDateStruct date: 2025-01-15, completionDateStruct date: 2025-12-30, studyFirstPostDateStruct date: 2024-04-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Universidad de Granada, class: OTHER, descriptionModule briefSummary: Extraction socket preservation is defined as alveolar ridge preservation within the bone envelope remaining after tooth extraction, meanwhile ridge augmentation is defined as increasing the volume of alveolar ridge beyond the bony envelope at the time of tooth extraction. It is recommended to use in cases where extraction socket anatomy is intact. In contrast definition "extraction socket augmentation" defines alveolar ridge restoration when bony walls of the socket are partly or completely lost. In the case of severe loss (\> 50%) of the buccal bone plate, preservation of hard tissue with a prolonged healing time before implant placement has been suggested.The null hypothesis of this experimental work states that: (i) the two different bone graft materials gained the same amount of bone following horizontal ridge augmentation procedure; (i) the two different bone graft materials exhibit similar histological and histomorphometric results Therefore, the main purpose of the current study is to compare two different biomaterials using guided bone regeneration procedures in the ridge preservation/ augmentation (hard-tissue preservation)., conditionsModule conditions: Edentulous Alveolar Ridge With Labial Resorption, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: * Group 1 (test group): Guided bone regeneration procedure with GTO® as bone graft and soft collagenated cortical membrane (OsteoBiol® Lamina; Tecnoss srl) as graft stabilizer.* Group 2 (control): Guided bone regeneration procedure with Apatos Mix® cortico-cancellous heterologous bone mix (OsteoBiol®; Tecnoss srl) as bone graft and soft collagenated cortical membrane (OsteoBiol® Lamina; Tecnoss srl) as graft stabilizer., primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: GTO®, outcomesModule primaryOutcomes measure: Dimensional bone changes, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Dental School, status: RECRUITING, city: Granada, zip: E18071, country: Spain, contacts name: Manuel Toledano, Professor, role: CONTACT, email: toledano@ugr.es, contacts name: Raquel Osorio, role: CONTACT, email: rosorio@ugr.es, contacts name: Manuel Toledano, Professor, role: PRINCIPAL_INVESTIGATOR, contacts name: Raquel Osorio, Professor, role: SUB_INVESTIGATOR, contacts name: Cristina Vallecillo, PhD, role: SUB_INVESTIGATOR, contacts name: Marta Vallecillo-Rivas, PhD, role: SUB_INVESTIGATOR, contacts name: Manuel Toledano-Osorio, PhD, role: SUB_INVESTIGATOR, geoPoint lat: 37.18817, lon: -3.60667, hasResults: False