protocolSection identificationModule nctId: NCT06348511, orgStudyIdInfo id: 0165-22-TLV, briefTitle: XTics - A Gamified Enhancer of Non-Pharmacological Interventions in Tic Disorders, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-07-01, primaryCompletionDateStruct date: 2022-12-31, completionDateStruct date: 2022-12-31, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Tel-Aviv Sourasky Medical Center, class: OTHER_GOV, descriptionModule briefSummary: The investigators developed a neuroscientifically-informed gamified tic-therapy platform. The investigators previously identified tic-triggering elements in movies and video games. Next, the investigators employed these elements to generate and validate a gamified intervention protocol, which is based on a video game the investigators designed (called XTics). The study tests the efficacy of the gamified tool integrated in an exposure and response prevention (ERP) protocol to enhance both patient's compliance and clinical outcome., conditionsModule conditions: Tic Disorders, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: The study tested the impact of contingent and immediate reward (ICR) given by the game in respect to the participant's tic frequency relative to a random and non-contingent delayed reward (DR) provided by the end of the training day. Each participant underwent three training days in each of the the modes during one week. The training days included 3 (first day) or 4 (second and third days) game sessions. The order of the training modes was random., primaryPurpose: DIAGNOSTIC, maskingInfo masking: SINGLE, maskingDescription: Personnel who interact directly with the study subjects were not aware of the assigned treatments. Personnel who analyze the data collected from the study are not aware of the treatment applied to any given group., whoMasked: INVESTIGATOR, enrollmentInfo count: 35, type: ACTUAL, armsInterventionsModule interventions name: XTics, outcomesModule primaryOutcomes measure: The Tic Yale Global Tic Severity Scale (YGTSS), primaryOutcomes measure: The Parent Tic Questionnaire (PTQ), primaryOutcomes measure: Premonitory Urge for Tic Scale (PUTS), primaryOutcomes measure: The Subjective Units of Distress Scale (SUDS), primaryOutcomes measure: The "Urge Thermometer", primaryOutcomes measure: Rush Videotape Protocol, primaryOutcomes measure: Tic-to-tic interval, secondaryOutcomes measure: The Screen for Child Anxiety Related Emotional Disorders (SCARED), secondaryOutcomes measure: The Children Depression Inventory (CDI), secondaryOutcomes measure: The Conners' Parent Rating Scale-Revised Long Form (CRS:RL), secondaryOutcomes measure: Obsessive Compulsive Inventory-Child Version (OCI-CV), secondaryOutcomes measure: The Behavior Rating Inventory of Executive Function (BRIEF), secondaryOutcomes measure: The Emotion Regulation Questionnaire (ERQ), secondaryOutcomes measure: User Engagement Scale (UES), eligibilityModule sex: ALL, minimumAge: 7 Years, maximumAge: 15 Years, stdAges: CHILD, contactsLocationsModule locations facility: Sagol Brain Institute, Tel Aviv Sourasky Medical Center, city: Tel Aviv, country: Israel, geoPoint lat: 32.08088, lon: 34.78057, hasResults: False