hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06316037, orgStudyIdInfo id: 2024 DUTHEIL ADAPTAWORK_2, briefTitle: Adaptation of Work in a Hospital and Assessment of Feelings of Quality of Life at Work, Teleworking and Face-to-face, acronym: ADAPTAWORK_2, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-09-12, primaryCompletionDateStruct date: 2024-01-20, completionDateStruct date: 2024-01-20, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: University Hospital, Clermont-Ferrand, class: OTHER, descriptionModule briefSummary: The ADAPTAWORK_2 study is a follow-up to the first qualitative study, to evaluate the feelings of hospital workers in all occupations about teleworking. This involves measuring the variation between three periods: before the COVID-19 pandemic, during the first lockdown an after the pandemic.Secondary objectives were: 1) to evaluate wich factors were associated to the feelings towards teleworking, 2) to assess musculo-squeletal disorders among teleworkers and the other participants, 3) to assess psycho-social risks among teleworkers and the oher participants, and 4) to evaluate teleworking costs, conditionsModule conditions: Work-Related Stress, conditions: Work-Related Condition, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 945, type: ACTUAL, outcomesModule primaryOutcomes measure: Feeling about teleworking, secondaryOutcomes measure: Musculo-squeletic pain, secondaryOutcomes measure: psychosocial risks, secondaryOutcomes measure: purchases, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: CHU de Clermont-Ferrand, city: Clermont-Ferrand, country: France, geoPoint lat: 45.77966, lon: 3.08628, hasResults: False
protocolSection identificationModule nctId: NCT06316011, orgStudyIdInfo id: MCG-chestpain, briefTitle: MCG for Risk Stratifications of Patients With Chest Pain, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-20, primaryCompletionDateStruct date: 2024-04-30, completionDateStruct date: 2024-08-31, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Qilu Hospital of Shandong University, class: OTHER, descriptionModule briefSummary: This prospective cohort study is aimed at identification and risk stratification of patients who have symptoms of acute chest pain suspected with acute coronary syndrome （ACS） using Magnetocardiography （MCG）., conditionsModule conditions: Acute Coronary Syndrome, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 3620, type: ESTIMATED, armsInterventionsModule interventions name: Magnetocardiography, outcomesModule primaryOutcomes measure: Efficacy of MCG for the detection and risk stratification in patients with chest pain, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06315998, orgStudyIdInfo id: MCG-Structural, briefTitle: Diagnosis of Structural Heart Disease Using MCG, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-18, primaryCompletionDateStruct date: 2025-04-30, completionDateStruct date: 2025-09-30, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Qilu Hospital of Shandong University, class: OTHER, descriptionModule briefSummary: The purpose of this prospective cohort study is to determine the parameters of cardiac magnetic imaging to identify structural heart disease using use transthoracic echocardiography or cardiac magnetic resonance as reference standard., conditionsModule conditions: Structural Heart Abnormality, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 2914, type: ESTIMATED, armsInterventionsModule interventions name: Magnetocardiography, outcomesModule primaryOutcomes measure: The efficacy of the MCG in identifying structural heart disease, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06315946, orgStudyIdInfo id: 17E3241, briefTitle: Efficacy of a Cryogenic Medical Device on Skin Tags Versus a Comparator Product., statusModule overallStatus: COMPLETED, startDateStruct date: 2018-10-04, primaryCompletionDateStruct date: 2019-01-07, completionDateStruct date: 2019-03-11, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Oystershell NV, class: INDUSTRY, descriptionModule briefSummary: Evaluate the efficacy of the test medical device (Pixie® skin tag) in the treatment of skin tags versus a comparator product (Wortie® skin tag remover)., conditionsModule conditions: Skin Tags, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: INVESTIGATOR, enrollmentInfo count: 56, type: ACTUAL, armsInterventionsModule interventions name: Pixie® skin tag, interventions name: Wortie® Skin Tag Remover, outcomesModule primaryOutcomes measure: Percentage of subjects with successful treatment, secondaryOutcomes measure: Number of treatments, secondaryOutcomes measure: Visual aspect, secondaryOutcomes measure: Macrophotographs on skin tag remission, secondaryOutcomes measure: Evaluation of the skin condition, secondaryOutcomes measure: Degree of pain, secondaryOutcomes measure: Recording of adverse events, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: DERMSCAN - PharmScan, city: Villeurbanne, zip: 69100, country: France, geoPoint lat: 45.76667, lon: 4.88333, hasResults: False
protocolSection identificationModule nctId: NCT06315933, orgStudyIdInfo id: S-K1093, briefTitle: Anesthesia Neurodevelopmental Impact in Congenital Scoliosis Children, statusModule overallStatus: RECRUITING, startDateStruct date: 2020-01-13, primaryCompletionDateStruct date: 2025-12, completionDateStruct date: 2026-12, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Peking Union Medical College Hospital, class: OTHER, descriptionModule briefSummary: In the past, a large number of animal studies have suggested that anesthesia exposure has potential neurotoxic effects, resulting in persistent cognitive and behavioral deficits. At present, there is still a lack of sufficient clinical research evidence to prove whether anesthesia exposure has long-term effects on neurodevelopment. The existing clinical research data suggests that a single short-time anesthesia exposure in young children does not affect long-term neurodevelopmental outcomes. Early onset scoliosis, including congenital scoliosis, is a type of scoliosis deformity that occurs before the age of 10. Posterior scoliosis correction surgery is one of the common treatment. There is currently no research indicating the impact of early single or multiple long-duration anesthesia exposure on the neurological development of children with congenital scoliosis. The aim of this study is to determine the long-term effect of general anesthesia exposure on neurocognitive function and behavior in children with congenital scoliosis, in order to provide reference for related clinical work., conditionsModule conditions: General Anesthetics Toxicity, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: OTHER, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: General anesthesia, outcomesModule primaryOutcomes measure: full-scale intelligence quotient, FSIQ, secondaryOutcomes measure: Verbal Comprehension Index (VCI), Perceptual Reasoning/Organization Index (PRI/POI), Working Memory Index (WMI), Processing Speed Index (PSI), secondaryOutcomes measure: CBCL Total score, CBCL Internalizing score, CBCL Externalizing score, secondaryOutcomes measure: SDQ Emotional symptoms, SDQ conduct problems, SDQ hyperactivity, SDQ peer problems, SDQ total difficulties, SDQ prosocial behaviors, SDQ impact factor, eligibilityModule sex: ALL, minimumAge: 6 Years, maximumAge: 16 Years, stdAges: CHILD, contactsLocationsModule locations facility: Peking Union Medical College Hospital, status: RECRUITING, city: Beijing, state: Beijing, zip: 100730, country: China, contacts name: Lulu Ma, Dr., role: CONTACT, phone: 0086-010-13811049619, email: malulu@pumch.cn, geoPoint lat: 39.9075, lon: 116.39723, hasResults: False
protocolSection identificationModule nctId: NCT06315907, orgStudyIdInfo id: PBRC 2024-012, briefTitle: Development and Validation of a Brief Food Noise Questionnaire, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2024-04-25, primaryCompletionDateStruct date: 2024-05-24, completionDateStruct date: 2024-05-28, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-04-26, sponsorCollaboratorsModule leadSponsor name: Pennington Biomedical Research Center, class: OTHER, collaborators name: Weight Watchers International, descriptionModule briefSummary: The purpose of the research is to develop and test the reliability and validity of a brief questionnaire to measure food noise., conditionsModule conditions: Eating Behavior, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 400, type: ESTIMATED, armsInterventionsModule interventions name: Responses to survey questions, outcomesModule primaryOutcomes measure: Scores on the food noise questionnaire, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Pennington Biomedical Research Center, city: Baton Rouge, state: Louisiana, zip: 70806, country: United States, geoPoint lat: 30.45075, lon: -91.15455, hasResults: False
protocolSection identificationModule nctId: NCT06315894, orgStudyIdInfo id: PI-22-191, briefTitle: Supervised Computerized Active Program for People With Post-COVID Syndrome (SuperCAP Study), acronym: SuperCAP, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-10-03, primaryCompletionDateStruct date: 2024-10, completionDateStruct date: 2025-09, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia, class: OTHER, collaborators name: Institut de Recerca de la SIDA IrsiCaixa, collaborators name: Germans Trias i Pujol Hospital, descriptionModule briefSummary: SuperCAP study is a project aimed at designing and implementing an online program for improvement of cognitive, emotional, and functional status in post-COVID condition., conditionsModule conditions: Post-COVID Condition, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized Controlled Trial, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: SuperCAP Program, outcomesModule primaryOutcomes measure: Change in Self-reported Cognitive Functioning, secondaryOutcomes measure: Change in Performance-based Cognitive Functioning, secondaryOutcomes measure: Change in Depression Symptoms, secondaryOutcomes measure: Change in Anxiety Symptoms, secondaryOutcomes measure: Change in Daily Activities Functioning, secondaryOutcomes measure: Change in Physical Activity, secondaryOutcomes measure: Change in Quality of Life, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Germans Trias I Pujol Hospital, status: RECRUITING, city: Badalona, state: Barcelona, zip: 08916, country: Spain, contacts name: Jose A MUñoz-Moreno, MD,PhD, role: CONTACT, phone: 93 465 7897, email: jmuñoz@lluita.org, contacts name: Jose A. Muñoz-Moreno, MD,PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 41.45004, lon: 2.24741, hasResults: False
protocolSection identificationModule nctId: NCT06315881, orgStudyIdInfo id: OSU-23116, secondaryIdInfos id: NCI-2024-00666, type: REGISTRY, domain: CTRP (Clinical Trial Reporting Program), secondaryIdInfos id: U54CA287392, type: NIH, link: https://reporter.nih.gov/quickSearch/U54CA287392, briefTitle: Informing Oral Nicotine Pouch Regulations to Promote Public Health, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09-01, primaryCompletionDateStruct date: 2025-12-31, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Ohio State University Comprehensive Cancer Center, class: OTHER, collaborators name: National Cancer Institute (NCI), descriptionModule briefSummary: This clinical trial evaluates the characteristics of oral nicotine pouches (ONPs) to determine if they are a comparable substitute to cigarette or smokeless tobacco (ST) products. ONPs contain nicotine but no tobacco and are used primarily by adult tobacco uses in the United States (US). ONPs are recognized by the Food and Drug Administration as having lower risk than combustible cigarettes and are approved as a modified risk tobacco product. While ONPs have lower toxic risk than other tobacco products, acute and longer term harm related to their use has not been studied. Information gathered from this study may identify product characteristics of ONPs that improve successful switching from high-risk cigarettes or ST to lower risk ONPs., conditionsModule conditions: Tobacco-Related Carcinoma, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 160, type: ESTIMATED, armsInterventionsModule interventions name: Biospecimen Collection, interventions name: Cigarette, interventions name: Nicotine Oral Pouch, interventions name: Nicotine Oral Pouch, interventions name: Nicotine Oral Pouch, interventions name: Nicotine Oral Pouch, interventions name: Smokeless Tobacco, interventions name: Survey Administration, interventions name: Text Message-Based Navigation Intervention, outcomesModule primaryOutcomes measure: Increased nicotine delivery, primaryOutcomes measure: Liking, primaryOutcomes measure: Craving/withdrawal suppression, primaryOutcomes measure: Rate of switching to ONP, primaryOutcomes measure: Rate of switching to ONPs, eligibilityModule sex: ALL, minimumAge: 21 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ohio State University Comprehensive Cancer Center, city: Columbus, state: Ohio, zip: 43210, country: United States, contacts name: Brittney L. Keller-Hamilton, PhD, MPH, role: CONTACT, phone: 614-366-9652, contacts name: Brittney L. Keller-Hamilton, PhD, MPH, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 39.96118, lon: -82.99879, hasResults: False
protocolSection identificationModule nctId: NCT06315868, orgStudyIdInfo id: 5590, briefTitle: Breast Cancer Subtype Characterization Through Patient's Derived Organoids., acronym: BCinsightPDO, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-06-15, primaryCompletionDateStruct date: 2026-06-15, completionDateStruct date: 2027-06-15, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, class: OTHER, descriptionModule briefSummary: Development of tools to predict patients chemo-sensitivity and identification of corresponding biomarkers is an urgent challenge for BC patients lacking targeted therapies, such as TNBC, or for patients experiencing relapse after adjuvant chemotherapy or targeted therapies.The refinement of 3D-cultivation techniques, experienced in the last decade, has allowed cultivation of patients-derived cancer cells in organotypic structures, named patient-derived organoids (PDO), which preserve histologic, genomic and transcriptomic features of primary tumors. PDO allow propagation, pharmacological treatment and genetic manipulation of patients-derived cancer cells in a close to physiology setting, thus representing a promising tool in the development of personalized therapies, conditionsModule conditions: Breast Cancer, conditions: Organoids, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 306, type: ESTIMATED, outcomesModule primaryOutcomes measure: evaluate the histological and molecular conformity (yes/no) between PDO and matched primary and/or recurrent BC sample, in order to develop a live biobank of ER/PR+, HER2+ and TNBC PDO., primaryOutcomes measure: evaluate the sensitivity of ER/PR+, HER2+ and TNBC PDO to novel therapeutic agents in clinical trials for BC or other cancer types, secondaryOutcomes measure: test the sensitivity of PDO to splicing-targeting treatments, either alone or in combination with other therapies, secondaryOutcomes measure: test the synergizing effects of agents splicing-targeting treatments to immunotherapies by co-culture experiments with autologous immune cells, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: IRCCS Fondazione Policlinico A. Gemelli, status: RECRUITING, city: Roma, zip: 00168, country: Italy, contacts name: alba di leone, MD, role: CONTACT, phone: 0039 3474980503, email: alba.dileone@policlinicogemelli.it, geoPoint lat: 41.89193, lon: 12.51133, hasResults: False
protocolSection identificationModule nctId: NCT06315855, orgStudyIdInfo id: STUDY00006928, briefTitle: Leveraging Telehealth to Improve Oral Health Among Cancer Survivors, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-25, primaryCompletionDateStruct date: 2025-03-25, completionDateStruct date: 2025-12-25, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Georgetown University, class: OTHER, descriptionModule briefSummary: The investigators will conduct a 2-arm 6-month randomized clinical controlled trial to evaluate the effectiveness of an oral Telehealth Intervention (THI) in preventing cancer-related oral complications, improving oral health maintenance and oral health related quality of life, and reducing systemic inflammation compared to Usual Care (UC) among unselected cancer survivors., conditionsModule conditions: Oral Mucositis, conditions: Periodontal Diseases, conditions: Cancer, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Telehealth Intervention (THI), outcomesModule primaryOutcomes measure: mucositis, primaryOutcomes measure: gingival inflammation and periodontal disease, primaryOutcomes measure: tooth decay, primaryOutcomes measure: oral health related quality of life, secondaryOutcomes measure: systemic inflammation, secondaryOutcomes measure: overall health related quality of life, secondaryOutcomes measure: comorbidities, eligibilityModule sex: ALL, minimumAge: 25 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False
protocolSection identificationModule nctId: NCT06315829, orgStudyIdInfo id: IRB00429753, briefTitle: Artificial Intelligence-based Video Analysis to Detect Infantile Spasms, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2026-05, completionDateStruct date: 2026-05, studyFirstPostDateStruct date: 2024-03-18, lastUpdatePostDateStruct date: 2024-03-18, sponsorCollaboratorsModule leadSponsor name: Johns Hopkins University, class: OTHER, descriptionModule briefSummary: Infantile spasms are a type of seizure linked to developmental issues. Unfortunately, they are often misdiagnosed, causing delays in treatment. The purpose of this study is to develop a computer program that can reliably differentiate infantile spasms from similar, yet benign movements in videos. This computer program will learn from videos taken by parents of study participants. Quickly recognizing and treating infantile spasms is crucial for ensuring the best developmental outcomes., conditionsModule conditions: Infantile Spasms, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: Spasm Vision, outcomesModule primaryOutcomes measure: Model Sensitivity (Recall), primaryOutcomes measure: Model Specificity, primaryOutcomes measure: Model Positive Predictive Value (Precision), primaryOutcomes measure: Model Negative Predictive Value, eligibilityModule sex: ALL, maximumAge: 2 Years, stdAges: CHILD, contactsLocationsModule locations facility: Johns Hopkins Hospital, city: Baltimore, state: Maryland, zip: 21287, country: United States, contacts name: Glenn Rivera, MD, role: CONTACT, phone: 410-955-4259, email: griver14@jh.edu, geoPoint lat: 39.29038, lon: -76.61219, hasResults: False