hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06388447, orgStudyIdInfo id: UCMSC1, briefTitle: Reconstruction of Deficient Interdental Papilla Using Stem Cells vs Physiological Saline: a RCT, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2023-12-01, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2025-03-30, studyFirstPostDateStruct date: 2024-04-29, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: University of Malaya, class: OTHER, descriptionModule briefSummary: The goal of this study is to assess the reconstruction of interdental papilla following the injection of UC-MSCs or physiological saline in patients with interdental papilla deficiency. Participants will be randomised into 2 groups (intervention vs placebo) to receive the treatment., conditionsModule conditions: Gingival Recession, Localized, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 20, type: ESTIMATED, armsInterventionsModule interventions name: Umbilical cord-mesenchymal stem cells, outcomesModule primaryOutcomes measure: Reconstruction of the deficient interdental papilla with soft tissue, primaryOutcomes measure: Reconstruction of the deficient interdental papilla with bone, primaryOutcomes measure: Reconstruction of the deficient interdental papilla with bone, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Orthodontic Postgraduate Clinic, city: Kuala Lumpur, state: Wilayah Persekutuan Kuala Lumpur, zip: 50603, country: Malaysia, geoPoint lat: 3.1412, lon: 101.68653, hasResults: False
protocolSection identificationModule nctId: NCT06388421, orgStudyIdInfo id: GMS-PH-401, briefTitle: DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD), statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-08-01, primaryCompletionDateStruct date: 2030-08-01, completionDateStruct date: 2030-11-30, studyFirstPostDateStruct date: 2024-04-29, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: United Therapeutics, class: INDUSTRY, descriptionModule briefSummary: This is a prospective, non-interventional, multicenter, registry of patients with pulmonary associated with interstitial lung disease (PH-ILD)., conditionsModule conditions: Pulmonary Hypertension Due to Lung Diseases and Hypoxia, conditions: Pulmonary Hypertension, conditions: Interstitial Lung Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 1000, type: ESTIMATED, armsInterventionsModule interventions name: Prospective study assessments, outcomesModule primaryOutcomes measure: Baseline characteristics as described by demographics, medical history, ILD history, PH history, family history (comorbidities), and diagnostic right heart catheterization values, secondaryOutcomes measure: Changes in clinical features relating to patients' interstitial lung disease and pulmonary hypertension, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06388408, orgStudyIdInfo id: SufMAST, briefTitle: Effects of Sufentanil Target Controlled Infusion on Patient State Index Values and Electroencephalographic Spectrum During Total Intravenous Anesthesia With Propofol, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-05, primaryCompletionDateStruct date: 2024-09-15, completionDateStruct date: 2024-09-30, studyFirstPostDateStruct date: 2024-04-29, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: University of Padova, class: OTHER, descriptionModule briefSummary: Sufentanil Target Controlled infusion (TCI, Gepts model) effects on Neuromonitoring during Total Intravenous Anesthesia (TIVA) with Propofol TCI (Eleveld model) has not been investigate yet.Authors aim to investigate its effect on Patient State index (PSi), the power spectrum EEG, the Analgesia Nociception Index (ANI) nad pupillometry values during maintenance durin TIVA-TCI with Propofol and Sufentanil., conditionsModule conditions: Anesthesia Brain Monitor, conditions: Sufentanil, conditions: Target Controlled Infusion, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 40, type: ESTIMATED, outcomesModule primaryOutcomes measure: Effects of Sufentanil on Patient State index (PSi) during stable Propofol general anesthesia, primaryOutcomes measure: Effects of Sufentanil on Electroencephalogram (EEG) power spectrum during stable Propofol general anesthesia, primaryOutcomes measure: Effects of Sufentanil on Analgesia Nociception Index (ANI) during stable Propofol general anesthesia, secondaryOutcomes measure: Analgesia Nociception Index (ANI) values and postoperative pain, secondaryOutcomes measure: Patient State Index (PSi) values and postoperative delirium, secondaryOutcomes measure: Analgesia Nociception Index (ANi) values and postoperative delirium, eligibilityModule sex: FEMALE, minimumAge: 18 Years, maximumAge: 90 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Treviso Regional Hospital, city: Treviso, state: TV, zip: 31100, country: Italy, geoPoint lat: 45.66673, lon: 12.2416, hasResults: False
protocolSection identificationModule nctId: NCT06388382, orgStudyIdInfo id: UKKx2024, briefTitle: Investigation of the Audible ICD Alert Tone, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-15, primaryCompletionDateStruct date: 2025-05-15, completionDateStruct date: 2025-05-30, studyFirstPostDateStruct date: 2024-04-29, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: Universitätsklinikum Köln, class: OTHER, descriptionModule briefSummary: Ability of ICD patients to hear the audible ICD alert is being assessed., conditionsModule conditions: Implantable Defibrillator User, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 150, type: ESTIMATED, armsInterventionsModule interventions name: Alert tone demonstration, outcomesModule primaryOutcomes measure: Alert tone audible, eligibilityModule sex: ALL, minimumAge: 15 Years, maximumAge: 100 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University Hospital Cologne, city: Cologne, zip: 50937, country: Germany, geoPoint lat: 50.93333, lon: 6.95, hasResults: False
protocolSection identificationModule nctId: NCT06388369, orgStudyIdInfo id: CA184-608, briefTitle: Neoadjuvant Lu-PSMA Radioligand Therapy and Ipilimumab in Men With Very High-risk Prostate Cancer, acronym: NEPI, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2027-03, completionDateStruct date: 2028-09, studyFirstPostDateStruct date: 2024-04-29, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: University Hospital, Essen, class: OTHER, collaborators name: Advanced Accelerator Applications, collaborators name: Bristol-Myers Squibb, descriptionModule briefSummary: A randomized, open-label Phase I/II study of neoadjuvant treatment with \[177Lu\]Lu-PSMA-617 radioligandtherapy (LuPSMA) with or without Ipilimumab in participants with very high-risk prostate cancer who are candidates for Radical Prostatectomy., conditionsModule conditions: Very High Risk Prostate Carcinoma, designModule studyType: INTERVENTIONAL, phases: PHASE1, phases: PHASE2, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: The first patients are enrolled - without randomization - into the Safety Cohort to assess whether the treatment regime under investigation, i.e. Ipilimumab (3mg/kg) + \[177Lu\]Lu-PSMA-617 RLT (7,4 GBq), is appropriately tolerated as per dose escalation algorithm.If it is established that Ipilimumab (3mg/kg) + \[177Lu\]Lu-PSMA-617 RLT (7,4 GBq) is appropriately tolerated, patients will be randomized into the two arms of the Analysis Cohort:* Arm A: Ipilimumab + \[177Lu\]Lu-PSMA-617 RLT* Arm B: \[177Lu\]Lu-PSMA-617 RLT, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 58, type: ESTIMATED, armsInterventionsModule interventions name: [177Lu]Lu-PSMA-617, interventions name: Ipilimumab, outcomesModule primaryOutcomes measure: Feasibility to perform prostatectomy on time, primaryOutcomes measure: Clinical activity: Proportion of participants in the full analysis set who achieve a pCR, secondaryOutcomes measure: Safety Profile of neoadjuvant treatment before radical prostatectomy, secondaryOutcomes measure: Safety Profile of neoadjuvant treatment before radical prostatectomy, eligibilityModule sex: MALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University Hospital Essen, Clinic of Urology, city: Essen, zip: 45147, country: Germany, contacts name: PD Dr. med. Ulrich Krafft, role: CONTACT, email: ulrich.krafft@uk-essen.de, geoPoint lat: 51.45657, lon: 7.01228, hasResults: False
protocolSection identificationModule nctId: NCT06388356, orgStudyIdInfo id: 042024, briefTitle: Patient's Informational Privacy in Prehospital Emergency Care - Educational Intervention Study for the Paramedics, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2024-03-25, primaryCompletionDateStruct date: 2024-05-19, completionDateStruct date: 2024-06-16, studyFirstPostDateStruct date: 2024-04-29, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: Eini Koskimies, class: OTHER, descriptionModule briefSummary: The main goal of this educational intervention study about patient's informational privacy (IP) is to evaluate the effect of the educational intervention into the paramedics' knowledge and attitude regarding patient's IP. The study also investigates the usability and the feasibility of the educational intervention.The main questions it aims to answer are:1. What is the effect of the educational intervention on the   1. theoretical knowledge of paramedics' regarding IP?   2. the paramedics' attitude towards patient's IP?2. What is the usability and feasibility of the intervention being evaluated according to the respondents?, conditionsModule conditions: Knowledge, conditions: Attitude of Health Personnel, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Two groups, intervention and control group. Only intervention group is receiveing the intervention., primaryPurpose: BASIC_SCIENCE, maskingInfo masking: NONE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: Educational intervention - Yksityisyyttä ensihoitoon / Informational privacy for preospital emergency care, outcomesModule primaryOutcomes measure: Paramedics' knowledge about patient's informational privacy, secondaryOutcomes measure: paramedics' attitude towards patient's informational privacy., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Turku, city: Turku, zip: 20520, country: Finland, geoPoint lat: 60.45148, lon: 22.26869, hasResults: False
protocolSection identificationModule nctId: NCT06388343, orgStudyIdInfo id: S68485, briefTitle: Causes of Listening Difficulties in Children, acronym: CLINIC, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2025-01, primaryCompletionDateStruct date: 2027-12, completionDateStruct date: 2027-12, studyFirstPostDateStruct date: 2024-04-29, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: Universitaire Ziekenhuizen KU Leuven, class: OTHER, collaborators name: Universitair Ziekenhuis Brussel, descriptionModule briefSummary: Many children experience listening and processing difficulties (LiD), especially in background noise, despite normal hearing sensitivity. The prevalence of these problems is estimated at 0.5-1% in the general population. Listening difficulties are associated with developmental disorders (DD) such as specific language disorders, autism spectrum disorder (ASD), ADHD and learning disabilities. Many children with developmental problems are easily distracted by sounds, have difficulty concentrating for long periods, processing language, remembering and summarizing oral information, and can experience academic difficulties (reading, writing). Early identification, differential diagnosis and intervention are important to help children overcome these difficulties and reach their full potential. Some concerns about these listening and processing problems, such as the lack of a gold standard to diagnose LiD and age-appropriate reference data, led to the initiation of this study.CLINIC aims to develop a new approach to diagnose the causes of listening difficulties in children. This is accomplished through (1) a validated parent questionnaire and (2) a multidisciplinary behavioral assessment tool. Data from these combined measures will lead to evidence-based profiles of children with LiD, which in turn will help streamline their referral pathways and care pathways., conditionsModule conditions: Listening Difficulties, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: DIAGNOSTIC, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 280, type: ESTIMATED, armsInterventionsModule interventions name: Evaluation of Children's Listening and Processing Skills, interventions name: Multidisciplinary behavioral assessment, outcomesModule primaryOutcomes measure: ECLiPS questionnaire, primaryOutcomes measure: Behavioral measures, eligibilityModule sex: ALL, minimumAge: 6 Years, maximumAge: 14 Years, stdAges: CHILD, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06388330, orgStudyIdInfo id: s61692, briefTitle: The Effect of a Low FODMAP Diet in Functional Dyspepsia Patients With Meal Related Symptoms, acronym: FFD, statusModule overallStatus: COMPLETED, startDateStruct date: 2019-04-26, primaryCompletionDateStruct date: 2022-03-08, completionDateStruct date: 2022-03-08, studyFirstPostDateStruct date: 2024-04-29, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: Universitaire Ziekenhuizen KU Leuven, class: OTHER, descriptionModule briefSummary: In this study, the investigators will evaluate the FODMAP diet as an alternative treatment for functional dyspepsia and explore its effect on different aspects of the pathophysiology of FD., conditionsModule conditions: Functional Dyspepsia, conditions: FODMAP Diet, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, maskingDescription: open label strict diet phase blinded participant during reintroduction, enrollmentInfo count: 32, type: ACTUAL, armsInterventionsModule interventions name: low FODMAP diet, outcomesModule primaryOutcomes measure: Improvement on gastrointestinal symptoms, secondaryOutcomes measure: Reintroduction period, secondaryOutcomes measure: Evaluation of the low FODMAP diet on IBS related symptoms, secondaryOutcomes measure: Evaluation of the low FODMAP diet on symptom response and quality of life, secondaryOutcomes measure: Evaluation of the low FODMAP diet on depression, somatization, secondaryOutcomes measure: Evaluation of the low FODMAP diet on duodenal barrier function, secondaryOutcomes measure: Evaluation of the low FODMAP diet on gastric emptying, secondaryOutcomes measure: Evaluation of the low FODMAP diet on gastric accommodation, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: KU Leuven, city: Leuven, state: Vlaams-Brabant, zip: 3000, country: Belgium, geoPoint lat: 50.87959, lon: 4.70093, hasResults: False
protocolSection identificationModule nctId: NCT06388317, orgStudyIdInfo id: 123632, briefTitle: Machine-based Algorithm for Increased Physical Activity and Sustained User Engagement, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-01-01, primaryCompletionDateStruct date: 2025-01-01, completionDateStruct date: 2025-02-01, studyFirstPostDateStruct date: 2024-04-29, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: Western University, Canada, class: OTHER, descriptionModule briefSummary: This 12-week study compares the effectiveness of personalized daily step goals generated by a machine learning algorithm in the Sprout app versus fixed daily step goals of 10,000 steps among adults. Participants will be recruited through the Sprout app, and after a 1-week run-in period, they will be assigned to either the intervention or control group. The intervention group will receive adaptive goals based on their historical step data, while the control group will have a fixed goal. Both groups will receive financial incentives. This study aims to inform future interventions measuring changes in daily steps and app engagement levels (i.e., time spent on app, number of app opens) by studying how using financial incentives and an adaptive goal-setting design can improve physical activity levels of app users, informed by a machine learning algorithm., conditionsModule conditions: Health Behavior, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Retrospective, quasi-experimental study., primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: Participants are unaware of the other intervention arm (i.e., adaptive step goals versus static step goals)., whoMasked: PARTICIPANT, enrollmentInfo count: 500, type: ESTIMATED, armsInterventionsModule interventions name: Adaptive Step Goal (Intervention), interventions name: Static Step Goal (Control), outcomesModule primaryOutcomes measure: Step count, secondaryOutcomes measure: Number of app opens, total time spent on app, number of pages opened, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Western University, city: London, state: Ontario, country: Canada, geoPoint lat: 42.98339, lon: -81.23304, hasResults: False
protocolSection identificationModule nctId: NCT06388304, orgStudyIdInfo id: 23-0556, briefTitle: THRIVE Study: Positive Affect Training for Endocrine Therapy Medication Adherence, acronym: THRIVE, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-12, primaryCompletionDateStruct date: 2024-10-12, completionDateStruct date: 2024-12-12, studyFirstPostDateStruct date: 2024-04-29, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: Joanna Arch, class: OTHER, descriptionModule briefSummary: The purpose of this study is to pilot and refine an online behavioral intervention based on Positive Affect Training (PAT) that aims to increase positive emotional attitudes and decrease negative emotional attitudes toward endocrine therapy (ET, i.e., anti-hormonal medication) and to increase positive affect and decrease negative affect more generally, among post-treatment breast cancer survivors who are prescribed ET to prevent recurrence of breast cancer., conditionsModule conditions: Breast Cancer, conditions: DCIS, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: NONE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: THRIVE Online PAT Program, outcomesModule primaryOutcomes measure: Acceptability of THRIVE intervention (AIM), primaryOutcomes measure: Feasibility of THRIVE intervention, primaryOutcomes measure: Client Satisfaction Survey, eligibilityModule sex: FEMALE, minimumAge: 21 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Colorado Boulder, status: RECRUITING, city: Boulder, state: Colorado, zip: 80309, country: United States, contacts name: Sienna Russel, role: CONTACT, phone: 720-897-1850, email: archlab@colorado.edu, contacts name: Madeline Nealis, MPH, role: CONTACT, phone: 720-897-1850, email: archlab@colorado.edu, contacts name: Joanna Arch, PhD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 40.01499, lon: -105.27055, hasResults: False
protocolSection identificationModule nctId: NCT06388265, orgStudyIdInfo id: 18/2018, Acta 26-6-2018, briefTitle: Emotional and Oral Characteristics of Patients That Attend a Dental Consultation for the Extraction of Third Molars, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-01-09, primaryCompletionDateStruct date: 2023-07-31, completionDateStruct date: 2023-07-31, studyFirstPostDateStruct date: 2024-04-29, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: University of Barcelona, class: OTHER, descriptionModule briefSummary: Analyze the level of anxiety, hemodynamic parameters, oral status, and satisfaction among patients undergoing third molar extraction, we will assess those who attend the Master of Oral Medicine, Surgery, and Implantology program at the University of Barcelona., conditionsModule conditions: Anxiety and Fear, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, enrollmentInfo count: 75, type: ACTUAL, armsInterventionsModule interventions name: Trifold information, outcomesModule primaryOutcomes measure: Changes in STAI-S, primaryOutcomes measure: Changes in MDAS, secondaryOutcomes measure: Changes in blood pressure, secondaryOutcomes measure: Changes in Heart rate, secondaryOutcomes measure: Changes in Oxygen saturation, secondaryOutcomes measure: Patient Satisfaction of procedure, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Hospital Odontològic Universitat de Barcelona, city: L'Hospitalet De Llobregat, state: Barcelona, zip: 08907, country: Spain, geoPoint lat: 41.35967, lon: 2.10028, hasResults: False