protocolSection identificationModule nctId: NCT06347237, orgStudyIdInfo id: NL84429.078.23, briefTitle: PsA Digital Phenotyping and Inflammation Drivers Study, acronym: PDPID, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2025-12, completionDateStruct date: 2025-12, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-04, sponsorCollaboratorsModule leadSponsor name: Jolanda Luime, class: OTHER, collaborators name: University of Oxford - Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, collaborators name: Aristotle University of Thessaloniki - Hipokrateion Hospital Thessaloniki, collaborators name: Portuguese Society of Rheumatology - The Rheumatic Diseases Portuguese Registry (Reuma.pt), descriptionModule briefSummary: The goal of this observational study is to develop and internally validate a machine learning model for detecting flare using a digital biomarker and a machine learning model for predicting flare, in patients with psoriatic arthritis. The main questions it aims to answer are:* In patients with psoriatic arthritis, is a digital biomarker capable of detecting a flare as compared to clinical defined flare by the rheumatologist?* In patients with psoriatic arthritis, what factors trigger a psoriatic arthritis flare ?Participants will be requested to:* Install app on their phone* Use a smartwatch* Complete questionnaires* Collect biological material, conditionsModule conditions: Psoriatic Arthritis, conditions: Flare Up, Symptom, conditions: Psoriatic Arthritis Aggravated, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 600, type: ESTIMATED, outcomesModule primaryOutcomes measure: Absence of flare in patients, secondaryOutcomes measure: Minimal disease Activity (MDA), secondaryOutcomes measure: Psoriatic Arthritis Disease Activity Score (PASDAS), secondaryOutcomes measure: Disease Activity Psoriatic Arthritis (DAPSA), secondaryOutcomes measure: Psoriatic Arthritis Impact of Disease (PsAID), secondaryOutcomes measure: Morning stiffness, otherOutcomes measure: Keystroke dynamics, otherOutcomes measure: Screen time, otherOutcomes measure: Accelerometer data, otherOutcomes measure: Gyroscope sensor data, otherOutcomes measure: Steps count, otherOutcomes measure: Physical activity intensity and categories, otherOutcomes measure: Motion, otherOutcomes measure: Distance, otherOutcomes measure: Pulse Ox, otherOutcomes measure: Respiration, otherOutcomes measure: Body battery, otherOutcomes measure: Stress (digital), otherOutcomes measure: Heart rate, otherOutcomes measure: Beat-to-beat intervals, otherOutcomes measure: Sleeping time, otherOutcomes measure: Sleeping type, otherOutcomes measure: Hand and feet photos, otherOutcomes measure: Hand and body movements videos, otherOutcomes measure: Medical history, otherOutcomes measure: Joint count, otherOutcomes measure: Enthesitis, otherOutcomes measure: Body surface area, otherOutcomes measure: Weight, otherOutcomes measure: Height, otherOutcomes measure: Abdominal circumference, otherOutcomes measure: ClASsification criteria for Psoriatic ARthritis (CASPAR) score, otherOutcomes measure: Demographics, otherOutcomes measure: VAS Pain, otherOutcomes measure: HAQ questionnaire, otherOutcomes measure: VAS patient global, otherOutcomes measure: PSAID questionnaire, otherOutcomes measure: SF-36 questionnaire, otherOutcomes measure: EQ5d questionnaire, otherOutcomes measure: Work Productivity and Activity Impairment (WPAI) questionnaire, otherOutcomes measure: Health care questionnaire, otherOutcomes measure: Patient Health Questionnaire (PHQ9) questionnaire, otherOutcomes measure: Perceived Stress Scale (PSS), otherOutcomes measure: Global Rating of Change (GRoC) Scale, otherOutcomes measure: Life events questionnaire, otherOutcomes measure: Digital literacy questionnaire, otherOutcomes measure: Inflammatory blood marker, otherOutcomes measure: Genetic variants, otherOutcomes measure: Gut microbiome, otherOutcomes measure: Stress (cortisol levels), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, hasResults: False