hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06296732, orgStudyIdInfo id: NCPHOI-2024-01, briefTitle: Abdominal Neuroblastoma Laparoscopic Surgery Risk Factors Stratification, acronym: ANLAP-R, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-10-19, primaryCompletionDateStruct date: 2026-10-26, completionDateStruct date: 2031-11-01, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Federal Research Institute of Pediatric Hematology, Oncology and Immunology, class: OTHER, collaborators name: Corporate Fund University Medical Centre, descriptionModule briefSummary: Surgery plays significant role in treatment of neurogenic tumors, both for benign ganglioneuroma and for high risk neuroblastoma. The world literature has accumulated large experience in laparoscopic surgery for abdominal neuroblastoma. The presence of IDRF (image-defined risk factors) and tumor size (\>4-7 cm) are considered as common contraindications for minimally invasive surgery in neuroblastoma. However, the recent studies have shown that presence of IDRF is not an absolute contraindication for laparoscopic surgery. This open-label, nonrandomized, observational, phase III evaluates role and weight of different surgical risk factors (including IDRF, tumor size, tumor localization, tumor volume/patient height ratio, previous open surgical procedures, previous chemotherapy etc.) in the laparoscopic neuroblastoma resections. The aim of this study is to create novel risk factors scoring system for laparoscopic surgery in abdominal neuroblastoma., conditionsModule conditions: Neuroblastoma, conditions: Ganglioneuroma, conditions: Ganglioneuroblastoma, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: Duration of surgery intervention, outcomesModule primaryOutcomes measure: Duration of surgery intervention, secondaryOutcomes measure: The influence of surgical risk factors, secondaryOutcomes measure: Cases of conversion from laparoscopic to cavity access, secondaryOutcomes measure: Comparison of surgeon's visual assessment of the tumor resection, secondaryOutcomes measure: 1-, 3-, 5-years local recurrence-free survival, eligibilityModule sex: ALL, minimumAge: 1 Day, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Research Institute of Pediatric Hematology, Oncology and Immunology, status: RECRUITING, city: Moscow, country: Russian Federation, contacts name: Dmitry m Akhaladze, MD, Doc, role: CONTACT, phone: +7 (905) 587-89-92,, email: d.g.akhaladze@gmail.com, geoPoint lat: 55.75222, lon: 37.61556, hasResults: False
protocolSection identificationModule nctId: NCT06296719, orgStudyIdInfo id: ACP Community 2024, briefTitle: The Chit-Chat Educational Intervention to Promote Advance Care Planning in the Community, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2025-06, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: The Hong Kong Polytechnic University, class: OTHER, descriptionModule briefSummary: The purpose of this study is to estimate the effect size of the Chit-Chat intervention on ACP engagement among family members of older adults with multi-morbidity., conditionsModule conditions: Old Age, conditions: Family Members, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Chit-Chat, outcomesModule primaryOutcomes measure: ACP engagement, secondaryOutcomes measure: Knowledge of ACP, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06296706, orgStudyIdInfo id: HB1801-010, briefTitle: A Clinical Study of Docetaxel for Injection (Albumin-bound) in Patients With Gastric Cancer, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2026-06-01, completionDateStruct date: 2027-06-01, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: CSPC ZhongQi Pharmaceutical Technology Co., Ltd., class: INDUSTRY, descriptionModule briefSummary: This trial is a multicenter, randomized, controlled phase Ш clinical study of comparison of Docetaxel for Injection (Albumin-bound) and Taxotere in locally advanced or metastatic gastric adenocarcinoma or gastroesophageal junction adenocarcinoma with previous first-line treatment failure., conditionsModule conditions: Gastric Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 630, type: ESTIMATED, armsInterventionsModule interventions name: Docetaxel for injection (Albumin-bound), interventions name: Taxotere (docetaxel), outcomesModule primaryOutcomes measure: OS, secondaryOutcomes measure: ORR by IRC, secondaryOutcomes measure: ORR by investigator, secondaryOutcomes measure: PFS, secondaryOutcomes measure: DCR, secondaryOutcomes measure: DoR, secondaryOutcomes measure: AE and SAE, secondaryOutcomes measure: Plasma concentration of docetaxel (free and total), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06296667, orgStudyIdInfo id: P.T.REC/012/003644, briefTitle: Effect of Core Muscles Training On Patients With Chronic Mechanical Low Back Pain According To SALIBA'S Postural Classification System, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2023-05-01, primaryCompletionDateStruct date: 2024-03-15, completionDateStruct date: 2024-04-01, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Cairo University, class: OTHER, descriptionModule briefSummary: This study is designed as a pre and post experimental study. The purposes of this study are to evaluate the effect of core muscles training in patients with chronic mechanical low back pain according to SALIBA'S postural classification system (SPCS) in terms of pain intensity, function, and core muscles endurance., conditionsModule conditions: Chronic Low-back Pain, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 60, type: ACTUAL, armsInterventionsModule interventions name: core muscles training exercises, outcomesModule primaryOutcomes measure: pain intensity., primaryOutcomes measure: function disability, primaryOutcomes measure: core muscles endurance, otherOutcomes measure: participants gender will be male and females, their age in years,their height in meters,weight in kilograms., eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule locations facility: Cairo University,Faculty of Physical Therapy, city: Giza, zip: 11432, country: Egypt, geoPoint lat: 30.00808, lon: 31.21093, hasResults: False
protocolSection identificationModule nctId: NCT06296654, orgStudyIdInfo id: 25/2021-22 dt. Dec. 12,2021, briefTitle: Effect of Empowerment-Based Interventions on Self-Efficacy and Self-Care Capacity Among Adults With Sickle Cell Disease, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-03-20, primaryCompletionDateStruct date: 2022-10-21, completionDateStruct date: 2022-10-22, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: University of Bahrain, class: OTHER, descriptionModule briefSummary: This study aimed to To investigate the effect of empowerment-based interventions (EBI) on self-efficacy and self-care capacity among adults with Sickle Cell Disease (SCD).The hypotheses of this study were: Adults with SCD who receive EBI exhibit higher self-efficacy, self- management capacity and HRQoL than those who do not., conditionsModule conditions: Self-Efficacy, conditions: Self-Care, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: SUPPORTIVE_CARE, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 68, type: ACTUAL, armsInterventionsModule interventions name: Empowerment-Based Interventions, interventions name: Standard Health Education, outcomesModule primaryOutcomes measure: Sickle Cell Self-Efficacy, secondaryOutcomes measure: Self-Care Capacity, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: College of Health and Sport Sciences, University of Bahrain, city: Manama, zip: 11511, country: Bahrain, geoPoint lat: 26.22787, lon: 50.58565, hasResults: False
protocolSection identificationModule nctId: NCT06296641, orgStudyIdInfo id: AAAU9477, briefTitle: Needs Navigation for Caregivers of AYAs, acronym: Cope-CAYAC, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-16, primaryCompletionDateStruct date: 2025-02, completionDateStruct date: 2025-05, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Columbia University, class: OTHER, descriptionModule briefSummary: The overall aim of the study is to address unmet health-related social needs and reduce outcome disparities among AYA cancer survivors. Aim 1 aimed to refine a needs navigation model in partnership with expert consultants. Aim 2 and 3 will involve the deployment and pilot testing of the adapted needs navigation intervention among caregivers of younger AYAs with cancer., conditionsModule conditions: Cancer in Adolescence, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: Participants who screen positive all move forward to receive the intervention, primaryPurpose: HEALTH_SERVICES_RESEARCH, maskingInfo masking: NONE, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: Needs navigation intervention, outcomesModule primaryOutcomes measure: Number of (OR percentage of) participants who completed the intervention, primaryOutcomes measure: Percentage of eligible participants who consented to be in study, secondaryOutcomes measure: Personal Financial Wellness Scale (PFWS) / Comprehensive Score of Financial Toxicity (COST measure), eligibilityModule sex: ALL, minimumAge: 15 Years, maximumAge: 26 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Columbia University Irving Medical Center, status: RECRUITING, city: New York, state: New York, zip: 10032, country: United States, contacts name: Melissa Beauchemin, PhD, MSN,CPNP-PC, CPO, role: CONTACT, geoPoint lat: 40.71427, lon: -74.00597, hasResults: False
protocolSection identificationModule nctId: NCT06296628, orgStudyIdInfo id: 2000037049, secondaryIdInfos id: 000, type: OTHER, domain: CTGTY, briefTitle: Rehabilitation Device for Hand Mirror Therapy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2024-04, completionDateStruct date: 2024-04, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Yale University, class: OTHER, collaborators name: Management Center Innsbruck (MCI), Austria, collaborators name: Yale School of Engineering Center for Engineering 26 Innovation and Design, descriptionModule briefSummary: This study is a randomized and open comparative study that uses two parallel groups: a control group training with conventional therapy and another group that trains with the device "Miraπ". The participants are patients with stroke with motor weakness in one hand. Two measurement visits are required. During those visits, different hand function assessments will be carried out to analyze the motor function of the subjects hand. The measurements will be done during their inpatient rehabilitation stay, one at time of admission and the second at discharge, each taking 20 minutes. In the time between the measurement visits, the hand therapy takes place fivemtimes a week., conditionsModule conditions: Stroke, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Participants are patients admitted to the acute inpatient rehabilitation unit for rehabilitation of the hand and fingers who have one paralyzed hand without pronounced spasticity., primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 10, type: ESTIMATED, armsInterventionsModule interventions name: Miraπ, interventions name: Mirror Therapy, outcomesModule primaryOutcomes measure: Change in Jebsen-Taylor Hand Function Test score, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Yale New Haven Health Inpatient Rehabilitation Unit, Bridgeport Hospital, city: Bridgeport, state: Connecticut, zip: 06610, country: United States, geoPoint lat: 41.16704, lon: -73.20483, hasResults: False
protocolSection identificationModule nctId: NCT06296615, orgStudyIdInfo id: 2020-022, briefTitle: Whether Vaginal Microbiota Affects Pregnancy Outcomes After Embryo Transfer, statusModule overallStatus: COMPLETED, startDateStruct date: 2021-04-01, primaryCompletionDateStruct date: 2022-10-30, completionDateStruct date: 2022-10-30, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: ShangHai Ji Ai Genetics & IVF Institute, class: OTHER, descriptionModule briefSummary: The goal of this observational study is to learn about vaginal microbial characteristics in the patients under in vitro fertilization treatment. The study aims to address the following questions: (1) Is there any difference in microbial composition between the pregnancy and non-pregnancy groups? (2) Is there any differences in specific bacterial species between the two groups? (3) What are the favorable or unfavorable profiles of vaginal microbiota associated with achieving pregnancy? Patients will be asked to complete a questionnaire regarding their basic characteristics, and vaginal secretions will be collected via vaginal swab during frozen-blastocyst transfer procedures. The study will compare vaginal microbiota between pregnant and non-pregnant patients to assess its potential influence on clinical outcomes., conditionsModule conditions: Infertility, Female, conditions: Microbial Colonization, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 161, type: ACTUAL, outcomesModule primaryOutcomes measure: Rate of clinical pregnancy, eligibilityModule sex: FEMALE, minimumAge: 20 Years, maximumAge: 40 Years, stdAges: ADULT, contactsLocationsModule locations facility: Shanghai Ji Ai Genetics & IVF Institute, city: Shanghai, country: China, geoPoint lat: 31.22222, lon: 121.45806, hasResults: False
protocolSection identificationModule nctId: NCT06296602, orgStudyIdInfo id: 2023/777, briefTitle: Screening Anal HPV Colonization in Men Sex Men Using Pre-exposure Prophylaxis for HIV (ANAPreP'HPV), acronym: ANAPreP'HPV, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-04, primaryCompletionDateStruct date: 2024-11-04, completionDateStruct date: 2024-11-04, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: Centre Hospitalier Universitaire de Besancon, class: OTHER, descriptionModule briefSummary: This is an interventional study investigating HPV carriage and liquid-based cytology at anal level. It will be offered to all patients undergoing PreP consultations at Besançon University Hospital. The anal swab will be taken by the doctor using a cyto-brush during the consultation., conditionsModule conditions: Pre-Exposure Prophylaxis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, interventionModelDescription: A prelevement for HPV genotyping and anal cytology will be carried out in addition to the anal swabs taken quarterly to screen for other sexually transmitted infections.A questionnaire will be completed by the doctor to record the data of interest., primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: A prelevement for HPV genotyping and anal cytology will be carried out in addition to the anal swabs taken quarterly to screen for other sexually transmitted infections., outcomesModule primaryOutcomes measure: prevalence HPV, primaryOutcomes measure: typing HPV, secondaryOutcomes measure: High risk HPV risk factors, secondaryOutcomes measure: Cytologist abnormalies, eligibilityModule sex: MALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: CHU Besançon, status: RECRUITING, city: Besancon, zip: 25000, country: France, contacts name: Cédric LEBRETON, Dr, role: CONTACT, geoPoint lat: 47.24878, lon: 6.01815, hasResults: False
protocolSection identificationModule nctId: NCT06296589, orgStudyIdInfo id: HT94252310861, briefTitle: Trauma-Informed Guilt Reduction Therapy Compared to Prolonged Exposure, acronym: PORT, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06, primaryCompletionDateStruct date: 2027-07, completionDateStruct date: 2027-08, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Veterans Medical Research Foundation, class: OTHER, collaborators name: University of Minnesota, collaborators name: Center for Veterans Research and Education, descriptionModule briefSummary: The goal of this clinical trial is to learn if receiving Trauma-Informed Guilt Reduction (TrIGR) Therapy is as effective as receiving Prolonged Exposure Therapy among veterans with PTSD and trauma related guilt. The main questions it aims to answer are:Will TrIGR be comparable to PE in terms of PTSD symptom reduction? Will it TrIGR be comparable to PE in improving functioning and reducing depression symptoms? Will it be superior in improving trauma-related guilt and shame?, conditionsModule conditions: Stress Disorders, Post-Traumatic, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 158, type: ESTIMATED, armsInterventionsModule interventions name: Trauma Informed Guilt Reduction Therapy, interventions name: Prolonged Exposure Therapy, outcomesModule primaryOutcomes measure: Clinician Administered PTSD Scale for DSM-5 (CAPS-5), secondaryOutcomes measure: Patient Health Questionnaire-9 (PHQ-9), secondaryOutcomes measure: Brief Psychosocial Functioning Inventory (B-IPF), secondaryOutcomes measure: Trauma Related Guilt Inventory Cognitions Scale (TRGI), secondaryOutcomes measure: Trauma Related Shame Inventory (TRSI), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Little Rock Veterans Health Care System (LRVHCS), city: Little Rock, state: Arkansas, zip: 72205, country: United States, contacts name: Brandon Griffin, role: CONTACT, phone: 501-257-1000, email: Brandon.Griffin2@va.gov, geoPoint lat: 34.74648, lon: -92.28959, locations facility: Southeast Louisiana Veterans Health Care System (SLVHCS), city: New Orleans, state: Louisiana, zip: 70119, country: United States, contacts name: Laurel Franklin, PhD, role: CONTACT, phone: 800-935-8387, email: Laurel.Franklin@va.gov, geoPoint lat: 29.95465, lon: -90.07507, locations facility: William S. Middleton Memorial Hospital, city: Madison, state: Wisconsin, zip: 53705, country: United States, contacts name: Michael Messina, PhD, role: CONTACT, phone: 608-284-6302, email: Michael.Messina2@va.gov, geoPoint lat: 43.07305, lon: -89.40123, hasResults: False
protocolSection identificationModule nctId: NCT06296576, orgStudyIdInfo id: CHM-2023/S49/06, briefTitle: Acceleration Time Assessment for Prediction of Critical Limb Ischemia, acronym: ATACLI, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2026-05-01, completionDateStruct date: 2026-05-01, studyFirstPostDateStruct date: 2024-03-06, lastUpdatePostDateStruct date: 2024-03-06, sponsorCollaboratorsModule leadSponsor name: Centre Hospitalier le Mans, class: OTHER, descriptionModule briefSummary: Critical Limb Ischaemia (CLI), the final stage of arterial disease, is a therapeutic emergency whose prognosis depends largely on the time taken to diagnose it. The growing prevalence of this condition and the associated healthcare costs make it an important public health objective. Diagnostic criteria for Critical Limb Ischaemia differ between learned societies and countries.Its diagnosis is most frequently based on the combination of a clinical criterion (ischaemic decubitus pain and/or necrotic wounds, with a time to onset \> 2 weeks) and a haemodynamic criterion (ankle systolic pressure (ASP) \< 50mmHg or toe systolic pressure (TSP) \< 30 mmHg or transcutaneous oxygen pressure (TCPO2) \< 30 mmHg).Recent studies have highlighted the importance of pulsed Doppler flow analysis in quantifying arteriopathy of the lower limbs, both by systematically analysing flow modulation and by measuring the systolic rise time of distal arteries (dorsal artery of the foot and lateral plantar artery).The main aim of our study is therefore to validate a reliable and accessible diagnostic tool for screening patients suffering from CLI so that they can be referred to a reference centre as early as possible., conditionsModule conditions: Critical Limb Ischemia, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 431, type: ESTIMATED, armsInterventionsModule interventions name: arterial ultrasound scan, outcomesModule primaryOutcomes measure: Evaluate the intrinsic diagnostic performance of the maximum systolic rise time (TASmax) in the distal arteries of the foot, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Centre Hospitalier de CHOLET, city: Cholet, zip: 49300, country: France, contacts name: Marie GAUME, role: CONTACT, email: marie.gaume@ch-cholet.fr, contacts name: Jean-Eudes TRIHAN, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 47.06667, lon: -0.88333, locations facility: Centre Hospitalier du Mans, city: Le Mans, zip: 72000, country: France, contacts name: Christelle JADEAU, role: CONTACT, phone: 02 44 71 07 81, email: cjadeau@ch-lemans.fr, contacts name: Claire NEVEUX-BRECHETEAU, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 48.0, lon: 0.2, hasResults: False