protocolSection identificationModule nctId: NCT06356246, orgStudyIdInfo id: APHP240363, briefTitle: Oral Health Status of Cystic Fibrosis Patients. An Online Survey in Collaboration With the Vaincre la Mucoviscidose Patient Association., acronym: E-MUCODENT, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2024-08-01, completionDateStruct date: 2024-08-01, studyFirstPostDateStruct date: 2024-04-10, lastUpdatePostDateStruct date: 2024-04-10, sponsorCollaboratorsModule leadSponsor name: Assistance Publique - Hôpitaux de Paris, class: OTHER, collaborators name: Vaincre la Mucoviscidose, descriptionModule briefSummary: Cystic Fibrosis (CF) is a rare hereditary disease with autosomal recessive transmission, affecting 1 in 4700 births in France. Numerous studies have explored the links between oral health and CF, predominantly focusing on a children population. These studies reveal hyposalivation, a risk of dental erosion, an increased prevalence of enamel structural defects, but a reduced prevalence of dental caries in CF children, potentially explained by better oral hygiene. Periodontal disease does not appear to be increased in this population, while the oral quality of life of CF patients has been insufficiently studied.Today, emerging challenges arise due to the increased life expectancy of CF patients, attributed to the rise of modulators such as Kaftrio®, resulting in an adult-majority population in France. The study of periodontal diseases, associated with oral dysbiosis, becomes relevant as they represent bacterial reservoirs that could impact respiratory complications in CF patients.To deepen understanding of the links between oral health and CF, as well as to improve oral health of these patients, it is crucial to update the specific oral profile of this population. A cross-sectional survey using a questionnaire is proposed to include a large number of CF patients in France, aiming for real-life data. This questionnaire is constructed around internationally recognized tools for comparative analysis with normative data. Collaboration with the Patients Association "Vaincre la Mucoviscidose" (VLM) facilitates questionnaire creation, dissemination, and interpretation of results., conditionsModule conditions: Cystic Fibrosis, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 400, type: ESTIMATED, outcomesModule primaryOutcomes measure: Periodontal Risk Screening Score PESS, secondaryOutcomes measure: Assess the adherence to good oral hygiene practices and dental follow-up in adult CF patients according to French Union for Oral Health (UFSBD) 2021, secondaryOutcomes measure: Evaluate the risk of dental caries and tooth wear, secondaryOutcomes measure: Assess the oral quality of life, secondaryOutcomes measure: Evaluate oral dryness, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Marjolaine GOSSET, city: Ivry-sur-Seine, state: Ile-de-France, zip: 94270, country: France, contacts name: Marjolaine GOSSET, MD, PhD, role: CONTACT, phone: +33 (0)1 49 59 48 20, email: marjolaine.gosset@aphp.fr, contacts name: Anne Sophie Duflos, Vaincre La Mucoviscidose, role: CONTACT, phone: +33 (0)1 40 78 91 97, email: asduflos@vaincrelamuco.org, geoPoint lat: 48.81568, lon: 2.38487, hasResults: False