protocolSection identificationModule nctId: NCT06272435, orgStudyIdInfo id: PRO-FY2024-64, briefTitle: Beverage Hydration Index: Assessment of Four Rehydration Solutions, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-12-23, primaryCompletionDateStruct date: 2024-05-31, completionDateStruct date: 2024-05-31, studyFirstPostDateStruct date: 2024-02-22, lastUpdatePostDateStruct date: 2024-02-22, sponsorCollaboratorsModule leadSponsor name: University of Memphis, class: OTHER, descriptionModule briefSummary: No studies to date to evaluate the effects of the three different liquid IV electrolyte products on the beverage hydration index (BHI). Therefore, the purpose of this study is to determine the impact of three different LIV products (Hydration multiplier, Sugar Free formulation with Amino Acids, and Sugar Free with allulose) on hydration status in young and active men and women compared to a control (water). The study will follow the same approach as used by Maughan and colleagues (2016) to measure the fluid balance (the difference between the amount of water consumed and passed as urine) and BHI (the relative amount of urine passed after consumption of a drink compared to water) including time in positive fluid balance, as well as determining electrolyte concentrations, osmolality, specific gravity, and sodium and potassium in urine., conditionsModule conditions: Hydration, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: Semi-blinded, placebo controlled, crossover design, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: SINGLE, maskingDescription: Treatments will be labeled A-D. Subjects will be provided prepared beverages prepared in cup., whoMasked: PARTICIPANT, enrollmentInfo count: 28, type: ESTIMATED, armsInterventionsModule interventions name: Multiplier, interventions name: Sugar Free, interventions name: Sugar Free with Amino Acids, interventions name: Water, outcomesModule primaryOutcomes measure: Beverage Hydration Index, primaryOutcomes measure: Beverage Hydration Index, primaryOutcomes measure: Beverage Hydration Index, primaryOutcomes measure: Beverage Hydration Index, primaryOutcomes measure: Beverage Hydration Index, secondaryOutcomes measure: Net Fluid Balance, secondaryOutcomes measure: Net Fluid Balance, secondaryOutcomes measure: Net Fluid Balance, secondaryOutcomes measure: Net Fluid Balance, secondaryOutcomes measure: Net Fluid Balance, secondaryOutcomes measure: Urine Osmolality, secondaryOutcomes measure: Urine Osmolality, secondaryOutcomes measure: Urine Osmolality, secondaryOutcomes measure: Urine Osmolality, secondaryOutcomes measure: Urine Osmolality, secondaryOutcomes measure: Urine Osmolality, secondaryOutcomes measure: Urine Sodium, secondaryOutcomes measure: Urine Sodium, secondaryOutcomes measure: Urine Sodium, secondaryOutcomes measure: Urine Sodium, secondaryOutcomes measure: Urine Sodium, secondaryOutcomes measure: Urine Sodium, secondaryOutcomes measure: Urine Potassium, secondaryOutcomes measure: Urine Potassium, secondaryOutcomes measure: Urine Potassium, secondaryOutcomes measure: Urine Potassium, secondaryOutcomes measure: Urine Potassium, secondaryOutcomes measure: Urine Potassium, secondaryOutcomes measure: Urine Specific Gravity, secondaryOutcomes measure: Urine Specific Gravity, secondaryOutcomes measure: Urine Specific Gravity, secondaryOutcomes measure: Urine Specific Gravity, secondaryOutcomes measure: Urine Specific Gravity, secondaryOutcomes measure: Urine Specific Gravity, secondaryOutcomes measure: Urine Specific Gravity, secondaryOutcomes measure: Sodium balance, secondaryOutcomes measure: Sodium balance, secondaryOutcomes measure: Sodium balance, secondaryOutcomes measure: Sodium balance, secondaryOutcomes measure: Sodium balance, secondaryOutcomes measure: Potassium balance, secondaryOutcomes measure: Potassium balance, secondaryOutcomes measure: Potassium balance, secondaryOutcomes measure: Potassium balance, secondaryOutcomes measure: Potassium balance, secondaryOutcomes measure: Body Mass, secondaryOutcomes measure: Body Mass, secondaryOutcomes measure: Mood and Digestive Questionnaire, secondaryOutcomes measure: Mood and Digestive Questionnaire, secondaryOutcomes measure: Mood and Digestive Questionnaire, secondaryOutcomes measure: Mood and Digestive Questionnaire, secondaryOutcomes measure: Mood and Digestive Questionnaire, secondaryOutcomes measure: Mood and Digestive Questionnaire, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 45 Years, stdAges: ADULT, contactsLocationsModule locations facility: Center for Nutraceutical and Dietary Supplement Research, status: RECRUITING, city: Memphis, state: Tennessee, zip: 38152, country: United States, contacts name: Jackie Pence, Ph.D., role: CONTACT, phone: 901-678-1547, email: jpence1@memphis.edu, contacts name: Richard J Bloomer, Ph.D., role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 35.14953, lon: -90.04898, hasResults: False