protocolSection identificationModule nctId: NCT06347705, orgStudyIdInfo id: 23-252, briefTitle: A Study of 2141-V11 in Combination With Standard Treatments in People With Prostate Cancer, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-28, primaryCompletionDateStruct date: 2029-03-28, completionDateStruct date: 2029-03-28, studyFirstPostDateStruct date: 2024-04-04, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: Memorial Sloan Kettering Cancer Center, class: OTHER, descriptionModule briefSummary: The purpose of this study is to see whether combining 2141-V11 with various standard treatments is an effective treatment approach for prostate cancer. 2141-V11 works by activating the immune system to find and kill cancer cells. Researchers will look at whether this treatment approach is able to completely get rid of cancer in participants, and they will check for the presence of minimal residual disease (MRD) in participants. MRD is a small number of cancer cells that can be detected in the body after treatment., conditionsModule conditions: Prostate Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 99, type: ESTIMATED, armsInterventionsModule interventions name: 2141-V11 Antibody, outcomesModule primaryOutcomes measure: Number of participants with a complete response or minimal residual disease., eligibilityModule sex: MALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities), status: RECRUITING, city: Basking Ridge, state: New Jersey, zip: 07920, country: United States, contacts name: Matthew Dallos, MD, role: CONTACT, phone: 646-888-4716, geoPoint lat: 40.70621, lon: -74.54932, locations facility: Memorial Sloan Kettering Monmouth (Limited protocol activities), status: RECRUITING, city: Middletown, state: New Jersey, zip: 07748, country: United States, contacts name: Matthew Dallos, MD, role: CONTACT, phone: 646-888-4716, geoPoint lat: 40.39652, lon: -74.09211, locations facility: Memorial Sloan Kettering Bergen (Limited Protocol Activities), status: RECRUITING, city: Montvale, state: New Jersey, zip: 07645, country: United States, contacts name: Matthew Dallos, MD, role: CONTACT, phone: 646-888-4716, geoPoint lat: 41.04676, lon: -74.02292, locations facility: Memorial Sloan Kettering Suffolk-Commack (Limited protocol activity), status: RECRUITING, city: Commack, state: New York, zip: 11725, country: United States, contacts name: Matthew Dallos, MD, role: CONTACT, phone: 646-888-4716, geoPoint lat: 40.84288, lon: -73.29289, locations facility: Memorial Sloan Kettering Westchester (Limited Protocol Activities), status: RECRUITING, city: Harrison, state: New York, zip: 10604, country: United States, contacts name: Matthew Dallos, MD, role: CONTACT, phone: 646-888-4716, geoPoint lat: 40.96899, lon: -73.71263, locations facility: Memorial Sloan Kettering Cancer Center (All protocol activites), status: RECRUITING, city: New York, state: New York, zip: 10065, country: United States, contacts name: Matthew Dallos, MD, role: CONTACT, phone: 646-888-4716, geoPoint lat: 40.71427, lon: -74.00597, locations facility: Memorial Sloan Kettering Nassau (Limited Protocol Activites), status: RECRUITING, city: Rockville Centre, state: New York, zip: 11553, country: United States, contacts name: Matthew Dallos, MD, role: CONTACT, phone: 646-888-4716, geoPoint lat: 40.65871, lon: -73.64124, hasResults: False