hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06304402, orgStudyIdInfo id: 7978-GOA, briefTitle: Comparing Shoulder Stretching and Percussive Massage on Shoulder Rotation and Attack Speed in Female Volleyball Players, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-10, primaryCompletionDateStruct date: 2024-05-01, completionDateStruct date: 2024-06-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Dokuz Eylul University, class: OTHER, descriptionModule briefSummary: This study aims to investigate the acute effects of PNF modified sleeper stretches and percussive massage treatment on shoulder rotation movements and attack speed in female volleyball players and compare these applications., conditionsModule conditions: Sports Physical Therapy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 56, type: ESTIMATED, armsInterventionsModule interventions name: The Percussive Massage Treatment, interventions name: The Proprioceptive Neuromuscular Facilitation Stretching, outcomesModule primaryOutcomes measure: Shoulder internal rotation range of motion, secondaryOutcomes measure: Attack Speed, eligibilityModule sex: FEMALE, minimumAge: 14 Years, maximumAge: 40 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Dokuz Eylul University, School of Physical Therapy and Rehabilitation, status: RECRUITING, city: İzmir, state: Balçova, zip: 35340, country: Turkey, contacts name: Gonca Sahiner, PhD, role: CONTACT, geoPoint lat: 38.41273, lon: 27.13838, hasResults: False
protocolSection identificationModule nctId: NCT06304389, orgStudyIdInfo id: BLUELIGHT-VNS, briefTitle: Effect of Blue Light on Vagus Nerve Stimulation in Patients With Refractory Epilepsy, acronym: BLUELIGHTVNS, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-07-01, primaryCompletionDateStruct date: 2023-07-01, completionDateStruct date: 2026-04, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Cliniques universitaires Saint-Luc- Université Catholique de Louvain, class: OTHER, descriptionModule briefSummary: Vagus nerve stimulation (VNS) is an adjunctive treatment for refractory epilepsy. Although widely used, there is still a substantial number of patients with insufficient response. Light, and particularly blue light, can stimulate alertness, attention and cognition through modulation of anatomical targets which are common to the vagal afferent network. This project aims at understanding how exposure to blue enriched light may influence VNS effects in patients with refractory epilepsy by exploring the modulation of a series of biomarkers of VNS action. This could possibly lead to new therapeutic strategies to increase efficacy of VNS., conditionsModule conditions: Refractory Epilepsy, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NON_RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Patients with refractory epilepsy (divided in non responders \& responders), and healthy subjects, primaryPurpose: BASIC_SCIENCE, maskingInfo masking: SINGLE, whoMasked: PARTICIPANT, enrollmentInfo count: 34, type: ESTIMATED, armsInterventionsModule interventions name: electroencephalography, electrocardiogram, pupillometry, evoked potentials, light administration, interventions name: transcutaneous vagus nerve stimulation, electroencephalography, pupillometry, electrocardiogram, light administration, outcomesModule primaryOutcomes measure: Effect of blue light on VNS biomarkers, primaryOutcomes measure: Effect of blue light on VNS biomarkers, primaryOutcomes measure: Effect of blue light on VNS biomarkers, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 60 Years, stdAges: ADULT, contactsLocationsModule locations facility: Cliniques Universitaires Saint Luc, status: RECRUITING, city: Woluwe-Saint-Lambert, zip: 1200, country: Belgium, contacts name: Inci Cakiroglu, Phd student, role: CONTACT, phone: +32470612917, email: inci.cakiroglu@uclouvain.be, contacts name: Inci Cakiroglu, Phd student, role: SUB_INVESTIGATOR, geoPoint lat: 50.84389, lon: 4.42912, hasResults: False
protocolSection identificationModule nctId: NCT06304376, orgStudyIdInfo id: OMFS/FSDC002, briefTitle: Evaluation of Shell Technique in Secondary Alveolar Cleft Grafting, acronym: Alveolar cleft, statusModule overallStatus: COMPLETED, startDateStruct date: 2022-03-12, primaryCompletionDateStruct date: 2023-11-30, completionDateStruct date: 2024-02-22, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: October 6 University, class: OTHER, collaborators name: Ministry of Health, Kuwait, descriptionModule briefSummary: This study aims to evaluate the sufficiency of Khoury shell technique for reconstruction of alveolar cleft. Khoury technique was carried out using cortical bone shell fixed away from alveolar bone using two micro-screws, which was harvested from anterior iliac bone crest. The gap between the shell cortical bone and the native alveolar bone was filled by cancellous bone which was harvested from anterior iliac crest bone. The whole graft was covered by collagen membrane. The volumetric bone gain of the defect was determined via CBCT., conditionsModule conditions: Alveolar Cleft, conditions: Alveolar Ridge Cleft, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 14, type: ACTUAL, armsInterventionsModule interventions name: Alveolar ridge grafting, outcomesModule primaryOutcomes measure: Volumetric bone gain, secondaryOutcomes measure: Eruption of the tooth in the cleft, eligibilityModule sex: ALL, minimumAge: 7 Years, maximumAge: 14 Years, stdAges: CHILD, contactsLocationsModule locations facility: Ministry of Health, Farwaniya Hospital, city: Al Farwānīyah, zip: 81004, country: Kuwait, geoPoint lat: 29.2775, lon: 47.95861, hasResults: False
protocolSection identificationModule nctId: NCT06304363, orgStudyIdInfo id: Braining booster, briefTitle: Braining - Evaluation of Acute Effects of Physical Exercise, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-09-01, primaryCompletionDateStruct date: 2025-12-31, completionDateStruct date: 2026-12-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Region Stockholm, class: OTHER_GOV, collaborators name: Karolinska Institutet, descriptionModule briefSummary: "Braining" is a clinical method for physical exercise as adjunctive therapy in psychiatric care. The core components are personnel-led group training sessions and motivating contact with psychiatric staff, as well as measurements and evaluations before and after a training period.The scientific purpose of this study is to investigate immediate and short-term effects of a booster-session of several Braining classes., conditionsModule conditions: Psychiatric Disorder, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 30, type: ESTIMATED, armsInterventionsModule interventions name: Braining, outcomesModule primaryOutcomes measure: Anxiety Visual Analogue Scale (VAS), secondaryOutcomes measure: Beck Anxiety Inventory BAI, secondaryOutcomes measure: Montgomery-Åsberg Depression Rating Scale MADRS, secondaryOutcomes measure: High sensitivity C-reactive protein hsCRP, secondaryOutcomes measure: Brain-derived neurotrophic factor BDNF, secondaryOutcomes measure: Telomerase activity, secondaryOutcomes measure: Motivational factors of continued exercise, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Region Stockholm, Psykiatri Sydväst (Psychiatric Clinic Psychiatry Southwest), city: Stockholm, zip: 14186, country: Sweden, geoPoint lat: 59.33258, lon: 18.0649, hasResults: False
protocolSection identificationModule nctId: NCT06304350, orgStudyIdInfo id: SGHDOT-24-20, briefTitle: Pembrolizumab Combined With Preoperative Chemotherapy (Albumin Paclitaxel+Carboplatin) Neoadjuvant Therapy for Resectable Locally Advanced (Stage II/III) Esophageal Squamous Cell Carcinoma, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-17, primaryCompletionDateStruct date: 2026-02-25, completionDateStruct date: 2026-12-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-13, sponsorCollaboratorsModule leadSponsor name: Tongji University, class: OTHER, descriptionModule briefSummary: This study is a prospective, single center, open label, single arm clinical study. Select resectable locally advanced (cT3-4aN0M0, cT1-3N1-2M0, cII/III stage) esophageal cancer with pathological diagnosis of squamous cell carcinoma for inclusion, receive pembrolizumab combined with platinum containing dual drug (albumin paclitaxel+carboplatin) treatment for 2 courses, and undergo surgery. After surgery, continue pembrolizumab immunotherapy. Using pCR as the main endpoint of the study, conditionsModule conditions: Esophageal Cancer, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 25, type: ESTIMATED, armsInterventionsModule interventions name: Combination of pembrolizumab and platinum containing dual drugs, outcomesModule primaryOutcomes measure: Pathological complete remission (pCR), secondaryOutcomes measure: Major pathological remission (MPR), secondaryOutcomes measure: R0 resection rate, secondaryOutcomes measure: Progression free survival (PFS), secondaryOutcomes measure: Total survival time (OS), secondaryOutcomes measure: Safety (incidence of adverse drug reactions), eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 75 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Shanghai General Hospital, status: RECRUITING, city: Shanghai, state: Shanghai, zip: 200080, country: China, contacts name: Jiang Fan, MD, role: CONTACT, phone: 02163240090, email: fan_jiang@tongji.edu.cn, contacts name: Jiang Fan, MD, role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 31.22222, lon: 121.45806, hasResults: False
protocolSection identificationModule nctId: NCT06304337, orgStudyIdInfo id: YXLL-KY-2023(162), briefTitle: Application of New Oropharyngeal Airway Management in Patients Undergoing Painless Gastroenteroscopy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-03, primaryCompletionDateStruct date: 2024-10-10, completionDateStruct date: 2025-03-03, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Qianfoshan Hospital, class: OTHER, descriptionModule briefSummary: The objective of this study was to investigate the application of new oropharyngeal airway management in patients undergoing painless gastroenteroscopy.To see if it can really solve the problem of airway obstruction during anesthesia.The incidence of hypoxia (Spo2\<90%, t\>10s) and severe hypoxia (Spo2\<85%) during anesthesia and sedation, as well as the incidence of cough and laryngeal spasm, as well as the dose, endoscopist satisfaction, and the incidence of various adverse events were observed.To accumulate clinical experience and reference of anesthesia in obese patients., conditionsModule conditions: Airway Management, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, enrollmentInfo count: 228, type: ESTIMATED, armsInterventionsModule interventions name: New oropharyngeal airway group, outcomesModule primaryOutcomes measure: Incidence of hypoxia (Spo2<90%,t>10s) and severe hypoxia (Spo2<85%) during anesthetic sedation, secondaryOutcomes measure: The incidence of choking, reflux aspiration and laryngeal spasm were recorded, secondaryOutcomes measure: The dose of additional drugs during the operation, secondaryOutcomes measure: Endoscopist satisfaction, secondaryOutcomes measure: Record adverse events that occur throughout the process, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 95 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06304324, orgStudyIdInfo id: 18/2023, briefTitle: Dexmedetomidine vs Dexamethasone in Popliteal Nerve Block, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-03-31, completionDateStruct date: 2025-04-30, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Poznan University of Medical Sciences, class: OTHER, descriptionModule briefSummary: Effect of Perineural Dexmedetomidine vs. Dexamethasone on the duration of popliteal nerve block for Anesthesia After Pediatric ankle/foot surgery., conditionsModule conditions: Ankle Disease, conditions: Ankle Injuries and Disorders, conditions: Foot Injury, conditions: Foot Diseases, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 90, type: ESTIMATED, armsInterventionsModule interventions name: 0.9% Sodium chloride, interventions name: 0.1mg/kg Dexamethasone, interventions name: 0.05ug/kg Dexmedetomidine, outcomesModule primaryOutcomes measure: time to the first need of opiate following the procedure, secondaryOutcomes measure: Face, Legs, Activity, Cry, Consolability (FLACC) Behavioral Scale, secondaryOutcomes measure: Face, Legs, Activity, Cry, Consolability (FLACC) Behavioral Scale, secondaryOutcomes measure: Face, Legs, Activity, Cry, Consolability (FLACC) Behavioral Scale, secondaryOutcomes measure: Face, Legs, Activity, Cry, Consolability (FLACC) Behavioral Scale, secondaryOutcomes measure: Face, Legs, Activity, Cry, Consolability (FLACC) Behavioral Scale, secondaryOutcomes measure: Face, Legs, Activity, Cry, Consolability (FLACC) Behavioral Scale, secondaryOutcomes measure: Face, Legs, Activity, Cry, Consolability (FLACC) Behavioral Scale, secondaryOutcomes measure: Face, Legs, Activity, Cry, Consolability (FLACC) Behavioral Scale, secondaryOutcomes measure: Face, Legs, Activity, Cry, Consolability (FLACC) Behavioral Scale, secondaryOutcomes measure: Neutrophil-to-lymphocyte ratio, secondaryOutcomes measure: Platelet-to-lymphocyte ratio, secondaryOutcomes measure: Platelet-to-lymphocyte ratio, secondaryOutcomes measure: Time to mobilization, eligibilityModule sex: ALL, minimumAge: 3 Months, maximumAge: 18 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Department of Spine Diseases and Pediatric Orthopedics, University of Medical Sciences, Poznań, Poland, city: Poznań, state: Wielkopolska, zip: 61-545, country: Poland, geoPoint lat: 52.40692, lon: 16.92993, hasResults: False
protocolSection identificationModule nctId: NCT06304298, orgStudyIdInfo id: 10/2023, briefTitle: NLR and PLR Levels Following iPACK Block in Knee Arthroplasty, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-01, primaryCompletionDateStruct date: 2025-07-01, completionDateStruct date: 2025-08-01, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Poznan University of Medical Sciences, class: OTHER, descriptionModule briefSummary: Effect of iPACK block on NLR and PLR following knee arthroplasty, conditionsModule conditions: Knee Arthropathy, conditions: Knee Osteoarthritis, conditions: Knee Pain Chronic, designModule studyType: INTERVENTIONAL, phases: PHASE4, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, enrollmentInfo count: 60, type: ESTIMATED, armsInterventionsModule interventions name: 0.9% Sodium Chloride Injection, interventions name: Ropivacaine 0.2% Injectable Solution, outcomesModule primaryOutcomes measure: Neutrophil-to-lymphocyte ratio, primaryOutcomes measure: Neutrophil-to-lymphocyte ratio, primaryOutcomes measure: Neutrophil-to-lymphocyte ratio, secondaryOutcomes measure: PLR, secondaryOutcomes measure: PLR, secondaryOutcomes measure: PLR, secondaryOutcomes measure: first need of opiate, secondaryOutcomes measure: Opioid Consumption, secondaryOutcomes measure: Pain score, secondaryOutcomes measure: Pain score, secondaryOutcomes measure: Pain score, secondaryOutcomes measure: Pain score, secondaryOutcomes measure: Pain score, secondaryOutcomes measure: Pain score, secondaryOutcomes measure: Pain score, eligibilityModule sex: ALL, minimumAge: 20 Years, maximumAge: 90 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06304285, orgStudyIdInfo id: 2023-ky421, briefTitle: A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2026-12-31, completionDateStruct date: 2026-12-31, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: The First Affiliated Hospital of University of Science and Technology of China, class: OTHER, descriptionModule briefSummary: The incidence of PD is high, and when the disease is serious to a certain extent, the effect of drugs to control symptoms decreases, resulting in a significant reduction in the quality of life of patients. Recent studies have found that these PD symptoms are closely related to the intestine. For several cases of PD syndrome patients complicated with chronic appendicitis, our research group conducted acupuncture on points related to constipation and chronic appendicitis, and found that constipation and related motor symptoms of patients could be significantly improved. Clinical studies have shown that acupuncture also has a certain therapeutic effect on non-motor symptoms of Parkinson's disease, such as anxiety and depression, decreased olfactory function, sleep disorders, constipation, early skeletal muscle pain, cognitive dysfunction, etc., which can delay the progression of the disease and improve the quality of life of patients. Starting from intestinal acupuncture, this project further clarified the role of acupuncture treatment in the comprehensive treatment of PD, conditionsModule conditions: Parkinson's Disease, conditions: Chronic Appendicitis, conditions: Acupuncture, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 84, type: ESTIMATED, armsInterventionsModule interventions name: Acupuncture treatment, interventions name: Sham acupuncture treatment, outcomesModule primaryOutcomes measure: Score of MDS Unified-Parkinson Disease Rating Scale III, eligibilityModule sex: ALL, minimumAge: 40 Years, maximumAge: 70 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The First Affiliated Hospital of University of Science and Technology of China, status: RECRUITING, city: Hefei, state: Anhui, zip: 230001, country: China, contacts name: Yuhua Chen, M.M.S., role: CONTACT, phone: +8615955236270, email: yh1215@mail.ustc.edu.cn, contacts name: Chao Han, M.D., role: CONTACT, phone: +8615255629713, email: chaohan@ustc.edu.cn, geoPoint lat: 31.86389, lon: 117.28083, hasResults: False
protocolSection identificationModule nctId: NCT06304272, orgStudyIdInfo id: Irrigation, briefTitle: Comparison Between Drinking Water and Normal Saline in Irrigating Traumatic Wound, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2026-09, completionDateStruct date: 2027-12, studyFirstPostDateStruct date: 2024-03-12, lastUpdatePostDateStruct date: 2024-03-12, sponsorCollaboratorsModule leadSponsor name: Patan Academy of Health Sciences, class: OTHER, descriptionModule briefSummary: There is a controversy regarding the roles of the Normal saline and Tap water in irrigation of the wound. It has been suggested that antiseptic solution including normal saline has cytotoxic effect while tap water damages the fibroblast. There are no high level evidence to support one type of solution over other, systematic review have found no difference in wound infection between irrigation with normal saline vs tap water. There are ten randomized controlled trial comparing tap water with normal saline for irrigating wound published between 1992 to 2016. These RCT are analyzed in three systemic review and meta-analysis published on 2016, 2019, 2022, which showed that tap water and normal saline has no difference in terms of infection rate. The infection rate observed in various studies ranges from 0-11.5% in normal saline group and 0-12.6% in tap water group with no statistically significant difference., conditionsModule conditions: Trauma, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Randomized, double blinded, parallel, non-inferiority trial, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, enrollmentInfo count: 440, type: ESTIMATED, armsInterventionsModule interventions name: Irrigating Traumatic Wound with Drinking Water, outcomesModule primaryOutcomes measure: Comparison between drinking water and normal saline in irrigating traumatic wound: Noninferiority trial., eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False