hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06281808, orgStudyIdInfo id: R490, briefTitle: Photon Counting Detector CT Image Quality, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-02-28, primaryCompletionDateStruct date: 2026-09-01, completionDateStruct date: 2026-12-31, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Reto Sutter, MD, class: OTHER, descriptionModule briefSummary: This study aims to compare subjective image quality and diagnostic accuracy of a photon counting detector computed tomography (PCD-CT) scanner compared with an energy integrating detector (EID)-CT scanner as the reference standard., conditionsModule conditions: Diagnostic Imaging, conditions: Tomography, X Ray Computed, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: DIAGNOSTIC, maskingInfo masking: NONE, enrollmentInfo count: 200, type: ESTIMATED, armsInterventionsModule interventions name: Photon Counting Detector CT, outcomesModule primaryOutcomes measure: Image Quality PCD CT, primaryOutcomes measure: Diagnostic Accuracy PCD CT, eligibilityModule sex: ALL, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06281795, orgStudyIdInfo id: 1.24., briefTitle: Neuromodulation of the Autonomic Nervous System in Athletes, acronym: NANSA, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-01-31, completionDateStruct date: 2026-01-31, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Bakulev Scientific Center of Cardiovascular Surgery, class: OTHER_GOV, collaborators name: Foundation for the Support of Physical Culture and Sports BECOME A CHAMPION, collaborators name: Autonomous Non-Profit organization of additional education sports school BECOME A CHAMPION, descriptionModule briefSummary: There are few studies in the literature that have evaluated the effects of using percutaneous stimulation of the auricular branch of the vagus nerve for sports purposes (to accelerate recovery after physical exertion). It has been demonstrated that tVNS in athletes improved the rate of heart rate recovery, reduced lactic acid levels in blood plasma, reduced pain, reduced overtraining syndrome and fatigue levels., conditionsModule conditions: Efficacy, Self, conditions: Fatigue; Muscle, Heart, conditions: Fatigue, Mental, conditions: Fatigue; Combat, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: 1:1 randomization of active stimulation vs. sham stimulation, primaryPurpose: TREATMENT, maskingInfo masking: TRIPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, enrollmentInfo count: 125, type: ESTIMATED, armsInterventionsModule interventions name: tVNS, outcomesModule primaryOutcomes measure: Dynamics of maximum oxygen consumption (VO2max)., primaryOutcomes measure: The dynamics of the treadmill speed at the level of the anaerobic threshold of metabolism., secondaryOutcomes measure: Dynamics of the treadmill speed at the level of the aerobic metabolism threshold of metabolism., secondaryOutcomes measure: The dynamics of the heart rate (HR) at the level of the anaerobic threshold of metabolism., secondaryOutcomes measure: The dynamics of the heart rate (HR) at the level of the aerobic threshold of metabolism., secondaryOutcomes measure: The dynamics of RMSSD., secondaryOutcomes measure: HF dynamics, secondaryOutcomes measure: Dynamics of the LF/HF ratio., eligibilityModule sex: ALL, minimumAge: 15 Years, maximumAge: 35 Years, stdAges: CHILD, stdAges: ADULT, contactsLocationsModule locations facility: Autonomous Non-Profit organization of additional education sports school BECOME A CHAMPION, city: Krasnodar, country: Russian Federation, geoPoint lat: 45.04484, lon: 38.97603, hasResults: False
protocolSection identificationModule nctId: NCT06281743, orgStudyIdInfo id: LST-Ped Survey, briefTitle: Attitudes to Decisions to Withdraw or Withhold Life-sustaining Treatments in Critically Ill Children, acronym: LSTPedSurvey, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2025-12, completionDateStruct date: 2026-12, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-03-15, sponsorCollaboratorsModule leadSponsor name: Göteborg University, class: OTHER, descriptionModule briefSummary: The aim of this study is to investigate attitudes on decisions to withdraw or withhold life-sustaining treatments in critically ill children in Swedish intensive care units. This is a survey among pediatric critical care physicians., conditionsModule conditions: Pediatric Disorder, conditions: Critical Illness, conditions: Ethics, Narrative, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Survey, outcomesModule primaryOutcomes measure: Attitudes and experiences -questionnaire, eligibilityModule sex: ALL, minimumAge: 1 Year, maximumAge: 100 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06281730, orgStudyIdInfo id: 23-009197, briefTitle: Use of New Generation Fetoscopes in Pregnancies Affected by Fetal Diseases Amenable to Fetoscopy Therapy, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-05, primaryCompletionDateStruct date: 2044-02, completionDateStruct date: 2044-02, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-04-09, sponsorCollaboratorsModule leadSponsor name: Mayo Clinic, class: OTHER, descriptionModule briefSummary: The Researchers are trying to determine feasibility and safety of performing surgery in the womb with the Karl Storz fetoscopes (a tool used to access the baby in the body of the mother). This are new and improved fetoscopes that are not yet approved by the FDA., conditionsModule conditions: In Utero Procedure Affecting Fetus or Newborn, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Karl Storz New Generation Fetoscope - curved 11508AAK, interventions name: Karl Storz New Generation Fetoscope - straight 11506AAK, outcomesModule primaryOutcomes measure: Adverse events, primaryOutcomes measure: Serious Adverse Events, primaryOutcomes measure: Device malfunctions, secondaryOutcomes measure: Mean gestational age at delivery, secondaryOutcomes measure: Successful Completion, secondaryOutcomes measure: Satisfaction scores, secondaryOutcomes measure: Live births, secondaryOutcomes measure: Neonatal deaths, eligibilityModule sex: FEMALE, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Mayo Clinic Minnesota, status: RECRUITING, city: Rochester, state: Minnesota, zip: 55905, country: United States, geoPoint lat: 44.02163, lon: -92.4699, hasResults: False
protocolSection identificationModule nctId: NCT06281691, orgStudyIdInfo id: GreenBladder, briefTitle: GreenBladder - Early Detection of Bladder Cancer in Residents in Greenland Using a Urinary Marker and a Mobile Cystoscopy Unit, statusModule overallStatus: ENROLLING_BY_INVITATION, startDateStruct date: 2023-04-28, primaryCompletionDateStruct date: 2024-07-01, completionDateStruct date: 2025-11-30, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Jørgen Bjerggaard Jensen, class: OTHER, collaborators name: Cepheid, collaborators name: Laborie Medical Technologies Inc., collaborators name: Vingmed Danmark A/S, collaborators name: OneMed A/S, descriptionModule briefSummary: The goal of this observational study is to evaluate whether a urinary biomarker (Xpert® Bladder Cancer Detection Test) can be used as a selection tool to decide which patients that should undergo cystoscopy in haematuria work-up or in other indications where bladder tumor is suspected. Hereby, the investigators will investigate in which patients where cystoscopy can be omitted, particularly in areas with limited access to urological service. With these more selected investigations, patients with bladder tumors will potentially be selected to earlier diagnosis compared to the current non-selected investigations with the inherent logistic and economical challenges. With this strategy, the investigators aim at improving the current poor prognosis for bladder cancer patients in Greenland., conditionsModule conditions: Urinary Bladder Neoplasms, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 150, type: ESTIMATED, armsInterventionsModule interventions name: Xpert® Bladder Cancer Detection Test, outcomesModule primaryOutcomes measure: Accuracy of urinary marker (Xpert Bladder Cancer Detection Test) in patients undergoing cystoscopy for bladder cancer investigation, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Department of Urology, Aarhus University Hopsital, city: Aarhus, zip: 8000, country: Denmark, geoPoint lat: 56.15674, lon: 10.21076, locations facility: Queen Ingrid's Hospital, city: Nuuk, zip: 3900, country: Greenland, geoPoint lat: 64.18347, lon: -51.72157, hasResults: False
protocolSection identificationModule nctId: NCT06281678, orgStudyIdInfo id: CIBI363A202, briefTitle: A Study of IBI363 in Subjects With Advanced Solid Malignancies, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2026-03-01, completionDateStruct date: 2026-12-31, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Innovent Biologics (Suzhou) Co. Ltd., class: INDUSTRY, descriptionModule briefSummary: This is a Phase 2, open-label, multicenter study designed to evaluate the efficacy, safety and tolerability of IBI363 (study drug) in subjects with advanced, refractory solid malignancies., conditionsModule conditions: Solid Tumors, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 160, type: ESTIMATED, armsInterventionsModule interventions name: IBI363, outcomesModule primaryOutcomes measure: Objective response rate (ORR), secondaryOutcomes measure: Adverse Event （AE）, secondaryOutcomes measure: Dose-limiting Toxicity （DLT）, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: University of Kansas Medcial Center Research Institute, city: Fairway, state: Kansas, zip: 66205, country: United States, contacts name: Saqib Abbasi, role: CONTACT, phone: 913-945-7545, email: sabbasi@kumc.edu, geoPoint lat: 39.02223, lon: -94.6319, hasResults: False
protocolSection identificationModule nctId: NCT06281652, orgStudyIdInfo id: Cognichess, briefTitle: Cognitive Intervention With Go and Chess in Early and Subjective Cognitive Decline, acronym: Cognichess, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-02-13, primaryCompletionDateStruct date: 2025-02-13, completionDateStruct date: 2025-02-13, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-03-01, sponsorCollaboratorsModule leadSponsor name: University of Milano Bicocca, class: OTHER, descriptionModule briefSummary: The goal of this clinical trial\]is to evaluate if learning to play traditional board games could improve cognition in subjects with mild cognitive impairment and subjective cognitive decline. The main questions it aims to answer are:* Do Go and Chess improve cognition?* Is a game better than the other? Is the effect of both games on cognition synergistic?* Do Go and Chess improve quality of life?* Do Go and Chess improve mood?* Do Go and Chess improve lifestyle?Participants will be randomized to one of four groups:* Group intervention with Go, once a week, for 12 weeks* Group intervention with Chess, once a week, for 12 weeks* Group intervention with Go and Chess, twice a week, for 12 weeks* Control group, conditionsModule conditions: Mild Cognitive Impairment, conditions: Subjective Cognitive Decline, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: OTHER, maskingInfo masking: NONE, enrollmentInfo count: 80, type: ESTIMATED, armsInterventionsModule interventions name: Go classes, interventions name: Chess classes, outcomesModule primaryOutcomes measure: General cognition, secondaryOutcomes measure: Digit Span Forward, secondaryOutcomes measure: Digit Span Backwards, secondaryOutcomes measure: Trail Making Test - part A, secondaryOutcomes measure: Trail Making Test - part B, secondaryOutcomes measure: Semantic fluency, secondaryOutcomes measure: Quality of life indicator, secondaryOutcomes measure: Depression, secondaryOutcomes measure: Lifestyle, eligibilityModule sex: ALL, minimumAge: 55 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Fondazione IRCCS San Gerardo dei Tintori, status: RECRUITING, city: Monza, state: Lombardia, zip: 20900, country: Italy, contacts name: Lucio Tremolizzo, MD, PhD, role: CONTACT, phone: +390392339082, email: lucio.tremolizzo@unimib.it, contacts name: Federico Emanuele Pozzi, MD, role: SUB_INVESTIGATOR, geoPoint lat: 45.58005, lon: 9.27246, hasResults: False
protocolSection identificationModule nctId: NCT06281639, orgStudyIdInfo id: RAPID, briefTitle: RAPID: a Comparison Study of a Novel Ultrasound Device of Automated Congenital Heart Imaging, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04-01, primaryCompletionDateStruct date: 2025-04-01, completionDateStruct date: 2025-04-01, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: University of Minnesota, class: OTHER, descriptionModule briefSummary: The RAPID ultrasound is a portable imaging device that captures a one point image from the subcostal region of the heart. The device is set on the patient's chest and captures the image in \&lt;1 minute. It uses ultrasound imaging energy that is similar to commercialized devices and safe for patients of all ages and sizes. The device is a non-significant risk and therefore will not require an IDE. Images from RAPID will be taken directly before or after the standard clinical PCU. Images taken from both the RAPID device and the standard PCU will be de-identified and stored securely in BOX for review by two independent cardiologists. Image reviews will be conducted within Box., conditionsModule conditions: Congenital Heart Disease, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: PROSPECTIVE, enrollmentInfo count: 50, type: ESTIMATED, armsInterventionsModule interventions name: RAPID, outcomesModule primaryOutcomes measure: RAPID imaging quality, eligibilityModule sex: ALL, maximumAge: 1 Year, stdAges: CHILD, contactsLocationsModule locations facility: University of Minnesota, city: Minneapolis, state: Minnesota, zip: 55414, country: United States, contacts name: Gwenyth Fischer, MD, role: CONTACT, phone: 612-625-6678, email: fisch662@umn.edu, geoPoint lat: 44.97997, lon: -93.26384, hasResults: False
protocolSection identificationModule nctId: NCT06281626, orgStudyIdInfo id: 2024_RIPH_01_Preservatif, briefTitle: Use of the Free Male Condom Scheme in Young Adults Aged 18 to 25, acronym: Préservatif, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-01, primaryCompletionDateStruct date: 2024-05-01, completionDateStruct date: 2024-10-01, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: Université de Reims Champagne-Ardenne, class: OTHER, descriptionModule briefSummary: For several years, the incidence of sexually transmitted infections (STIs) has been rising sharply, while that of HIV has stagnated. This is due to the decline in condom use since the late 1990s, despite the fact that condom are considered the only effective way to prevent STIs.In France, 40% of STIs concern young people aged 15 to 25. The national public health strategy aims to stem the circulation of HIV and eliminate STIs as a major public health problem by 2030. To achieve this, several measures have been implemented: reimbursement of male condoms on prescription (2018), 100% free contraception and prevention in sexual health consultation (2021), and more recently, free, non-prescription access to male condoms in pharmacies (end 2022)., conditionsModule conditions: Comdom, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_ONLY, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 2000, type: ESTIMATED, armsInterventionsModule interventions name: Data collection, outcomesModule primaryOutcomes measure: use of free male condoms, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 25 Years, stdAges: ADULT, contactsLocationsModule locations facility: Ufr Medecine Urca, city: Reims, zip: 51100, country: France, geoPoint lat: 49.25, lon: 4.03333, locations facility: Université de Reims Champagne Ardenne, city: Reims, zip: 51100, country: France, geoPoint lat: 49.25, lon: 4.03333, hasResults: False
protocolSection identificationModule nctId: NCT06281613, orgStudyIdInfo id: 2024-AMCOPTEO, briefTitle: Comparison of AMCOP Bioactivator and High-pull Headgear in Treating Skeletal Class II Hyperdivergent Pediatric Patients, statusModule overallStatus: ACTIVE_NOT_RECRUITING, startDateStruct date: 2024-03-03, primaryCompletionDateStruct date: 2024-04-01, completionDateStruct date: 2024-04-05, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-03-08, sponsorCollaboratorsModule leadSponsor name: University of Pavia, class: OTHER, descriptionModule briefSummary: The aim of the present study was to retrospectively compare the clinical use of high-pull headgear versus AMCOP bioactivators for hyperdivergent pediatric patients.Cephalometric radiographs from pediatric patients treated at the Unit of Orthodontics and Pediatric Dentistry, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy and at the private practice of Dr. Cardarelli, Isernia, Italy will be collected.Cephalometric tracing from Giannì analysis will be performed at the baseline (T0) and after 18 months of treatment (T1)., conditionsModule conditions: Skeletal Malocclusion, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: RETROSPECTIVE, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: AMCOP group, interventions name: High-pull headgear, outcomesModule primaryOutcomes measure: Change in cephalometric angular measurements, primaryOutcomes measure: Linear regressions, primaryOutcomes measure: Change in cephalometric linear measurements, eligibilityModule sex: ALL, minimumAge: 7 Years, maximumAge: 11 Years, stdAges: CHILD, contactsLocationsModule locations facility: Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia, city: Pavia, state: Lombardy, zip: 27100, country: Italy, geoPoint lat: 45.19205, lon: 9.15917, hasResults: False
protocolSection identificationModule nctId: NCT06281587, orgStudyIdInfo id: SNFyodorov, briefTitle: Pathogenetic Risk Factors for Corneal Graft Rejection, statusModule overallStatus: COMPLETED, startDateStruct date: 2011-01, primaryCompletionDateStruct date: 2019-01, completionDateStruct date: 2019-01, studyFirstPostDateStruct date: 2024-02-28, lastUpdatePostDateStruct date: 2024-02-28, sponsorCollaboratorsModule leadSponsor name: The S.N. Fyodorov Eye Microsurgery State Institution, class: OTHER_GOV, descriptionModule briefSummary: There are many predictors that may influence the development of corneal graft rejection after penetrating keratoplasty. In our study investigators analysed the results of keratoplasty and the risk factors for graft rejection.Investigators analysed data from 493 patients who underwent penetrating keratoplasty between 2011 and 2019. Keratoplasty outcomes were followed up at subsequent clinic visits until December 2021. Then, 93 medical records were selected (taking into account the completeness of the medical records) and divided into two groups based on the primary diagnosis that was an indication for keratoplasty: high-risk and low-risk patients. Investigators then estimated the survival time (clear graft) of the corneal graft using Kaplan-Meier statistical survival analysis. Investigators also investigated the factors that influence corneal graft opacity., conditionsModule conditions: Graft Rejection, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: RETROSPECTIVE, enrollmentInfo count: 93, type: ACTUAL, armsInterventionsModule interventions name: penetrating keratoplasty, outcomesModule primaryOutcomes measure: Cohort group Kaplan-Meier survival analysis (clear graft engraftment), eligibilityModule sex: ALL, minimumAge: 13 Years, maximumAge: 70 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations city: Krasnodar, zip: 350012, country: Russian Federation, geoPoint lat: 45.04484, lon: 38.97603, hasResults: False