hackint0sh/temp-data huggingface dataset:
protocolSection identificationModule nctId: NCT06326359, orgStudyIdInfo id: Soh-Med-24-02-03MD, briefTitle: Autologous Stromal Vascular Fraction in Treatment of Male Androgenic Alopecia, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03, primaryCompletionDateStruct date: 2024-10, completionDateStruct date: 2026-10, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Sohag University, class: OTHER, descriptionModule briefSummary: Evaluation of Safety and efficacy of autologous stromal vascular fraction derived from denovo versus platelet rich plasma enhanced donner site in treatment of male androgenic alopecia, conditionsModule conditions: Androgenic Alopecia, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 40, type: ESTIMATED, armsInterventionsModule interventions name: autologous stromal vascular fraction, outcomesModule primaryOutcomes measure: hair density, primaryOutcomes measure: hair shaft thickness, eligibilityModule sex: MALE, minimumAge: 18 Years, maximumAge: 55 Years, stdAges: ADULT, contactsLocationsModule, hasResults: False
protocolSection identificationModule nctId: NCT06326346, orgStudyIdInfo id: AMC2401, briefTitle: GIST Oral Paclitaxel(Liporaxel), statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-06-01, primaryCompletionDateStruct date: 2027-03-31, completionDateStruct date: 2027-03-31, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-27, sponsorCollaboratorsModule leadSponsor name: Asan Medical Center, class: OTHER, descriptionModule briefSummary: The purpose of this study is to evaluate safety and efficacy of Liporaxel for patients with GIST who failed on prior standard treatments, including imatinib, sunitinib, and regorafenib, and with low P-glycoprotein expression., conditionsModule conditions: Gastrointestinal Stromal Tumors, designModule studyType: INTERVENTIONAL, phases: PHASE2, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 28, type: ESTIMATED, armsInterventionsModule interventions name: Liporaxel, outcomesModule primaryOutcomes measure: 16 week disease control rate, secondaryOutcomes measure: Progression-free survival, secondaryOutcomes measure: Overall survival, secondaryOutcomes measure: Objective response rate, secondaryOutcomes measure: Adverse event assessed by NCI-CTCAE Version 5.0, eligibilityModule sex: ALL, minimumAge: 20 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Asan Medical Center, University of Ulsan College of Medicine, city: Seoul, state: Songpagu, zip: 138-736, country: Korea, Republic of, contacts name: Min-Hee Ryu, MD, PhD, role: CONTACT, phone: 82-2-3010-5936, email: miniryu@amc.seoul.kr, contacts name: Hyung-Don Kim, MD, PhD, role: CONTACT, phone: 82-2-3010-0236, email: kimhdmd@amc.seoul.kr, geoPoint lat: 37.566, lon: 126.9784, hasResults: False
protocolSection identificationModule nctId: NCT06326333, orgStudyIdInfo id: E.Kurul-E2-24-6176, briefTitle: Combination of Parasternal and Serratus Anterior Plane Block in Coronary Artery Bypass Graft Surgery, statusModule overallStatus: COMPLETED, startDateStruct date: 2024-02-07, primaryCompletionDateStruct date: 2024-03-27, completionDateStruct date: 2024-04-18, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-04-22, sponsorCollaboratorsModule leadSponsor name: Ankara City Hospital Bilkent, class: OTHER, descriptionModule briefSummary: Postoperative analgesia is a critical risk factor for the development of pulmonary and cardiovascular complications in coronary artery bypass graft (CABG) surgery. If patients with high pain levels cannot breathe effectively, it may lead to atelectasis, cardiac ischemia, and arrhythmias. This prolongs the time it takes for patients to be discharged and increases the frequency of postoperative pulmonary complications and postoperative morbidity.In addition to intravenous medications, various neuraxial and peripheral nerve blocks can be used in cardiac surgery. In recent years, neuraxial anesthesia has been avoided due to the use of intraoperative high-dose heparin. As an alternative, peripheral nerve blocks have recently gained popularity. Parasternal block (PSB) and serratus anterior plane block (SAPB) are very superficial and easy to reach. Recently, in the literature, the number of cases performed with these blocks under ultrasound guidance and the number of randomized controlled prospective studies have increased.With this study, it was aimed to observe the analgesic effects on both the sternum and the drain site by applying PSB and SAPB applications simultaneously in the postoperative analgesia of CABG patients., conditionsModule conditions: Parasternal Block, conditions: Serratus Anterior Plane Block, conditions: Acute Pain, conditions: Postoperative Analgesia, conditions: Cardiac Surgery, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: NA, interventionModel: SINGLE_GROUP, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 20, type: ACTUAL, armsInterventionsModule interventions name: Combined parasternal block and serratus anterior plane block, outcomesModule primaryOutcomes measure: Pain Scores, primaryOutcomes measure: Pain Scores, primaryOutcomes measure: Pain Scores, primaryOutcomes measure: Pain Scores, primaryOutcomes measure: Pain Scores, secondaryOutcomes measure: Remifentanyl Consumption, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 80 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ankara City Hospital, city: Çankaya, state: Ankara, zip: 06290, country: Turkey, geoPoint lat: 39.9179, lon: 32.86268, hasResults: False
protocolSection identificationModule nctId: NCT06326307, orgStudyIdInfo id: 247-05-21, briefTitle: Effectiveness of Puppet Modeling Technique on Children Undergoing Stressful Dental Procedures, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-01-01, primaryCompletionDateStruct date: 2023-12-01, completionDateStruct date: 2023-12-01, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: King Abdulaziz University, class: OTHER, descriptionModule briefSummary: The goal of this RCT is to compare puppet modeling technique vs tell show and do on children undergoing stressful dental procedures'* The main question\[s\] it aims to answer are:  1. To compare the effect of puppet modeling vs tell show and do on the cooperation of children during the administration of local anesthesia.  2. To compare the effect of puppet modeling vs tell show and do on the anxiety level of children during the administration of local anesthesia.type of study: clinical trial participant population/health conditions: HealthyIn this randomized crossover clinical trial, study subjects were randomly allocated into two groups:* Group I : Children who received puppet behavior guidance during their first visit and tell-show-do guidance in their second visit, 2 weeks later. (P-TSD)* Group II : Children who received the tell-show-do behavior guidance during their first visit and puppet behavioral guidance in their second visit, 2 weeks later.(TSD-P), conditionsModule conditions: Behavioral Guidance in Pediatric Dentistry, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: CROSSOVER, interventionModelDescription: * Group I : Children who received puppet behavior guidance during their first visit and tell-show-do guidance in their second visit, 2 weeks later. (P-TSD)* Group II: Children who received the tell-show-do behavior guidance during their first visit and puppet behavioral guidance in their second visit, 2 weeks later.(TSD-P), primaryPurpose: TREATMENT, maskingInfo masking: SINGLE, maskingDescription: Two evaluators, who are blinded to the experimented techniques, watched recorded videos of both groups separately and gave their behavior assessment., whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 41, type: ACTUAL, armsInterventionsModule interventions name: Tell Show and Do Guidance, interventions name: Puppet Guidance, outcomesModule primaryOutcomes measure: Heart rate, primaryOutcomes measure: Facial Image Scale, primaryOutcomes measure: Vehnam Anxiety Rating Scale, primaryOutcomes measure: Frankl behavior rating scale, primaryOutcomes measure: FLACC Pain scale, primaryOutcomes measure: Venham Scale of Dental behavior, eligibilityModule sex: ALL, minimumAge: 3 Years, maximumAge: 8 Years, stdAges: CHILD, contactsLocationsModule locations facility: King Abulaziz university dental hospital, city: Jeddah, state: Makkah, zip: 21589, country: Saudi Arabia, geoPoint lat: 21.54238, lon: 39.19797, hasResults: False
protocolSection identificationModule nctId: NCT06326294, orgStudyIdInfo id: 727/CNBS/23, briefTitle: Assessment of the Effectiveness of TA Versus LEEP for Cervical Cancer Risk Reduction in WLHIV in Mozambique, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-04, primaryCompletionDateStruct date: 2027-09, completionDateStruct date: 2027-12, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Instituto Nacional de Saúde, Mozambique, class: OTHER_GOV, collaborators name: M.D. Anderson Cancer Center, descriptionModule briefSummary: Given that WLWH are more likely to develop persistent HPV infection and CC, effective screening and the management and treatment of pre-cancerous cervical abnormalities is critical to decrease the global burden of cervical cancer. The vast majority of WLWH live in SSA, where resources are more constrained. Therefore, simple, affordable, and effective tools are needed for the prevention of cervical cancer in SSA. In this setting, the best method for treatment of screen-positive WLWH has not been determined. The proposed study will compare the effectiveness of TA vs. LEEP, for treating precursor lesions (CIN 2/3) and HPV infection in WLWH, identify the determinants of treatment failure, and develop a strategy to predict patients in whom treatment is likely to fail so that alternative treatments can be provided. Moreover, local evidence of the optimal method of treatments is necessary to inform health policy and promote adherence., conditionsModule conditions: HIV Infections, conditions: HPV Infection, conditions: CIN 2/3, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: To compare TA, an ablative cervical treatment modality, and LEEP, an excisional cervical treatment modality, in screen-positive WLWH patients, for eradication of hrHPV and effectiveness of treating biopsy-confirmed CIN 2/3., primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 4844, type: ESTIMATED, armsInterventionsModule interventions name: Thermal ablation, interventions name: LOOP ELECTROSURGICAL EXCISION PROCEDURE, outcomesModule primaryOutcomes measure: Comparison of treatment success rates for biopsy-confirmed CIN 2/3: Thermoablation (TA) vs. Loop Electrosurgical Excision Procedure (LEEP), eligibilityModule sex: FEMALE, minimumAge: 25 Years, maximumAge: 49 Years, stdAges: ADULT, contactsLocationsModule locations facility: INSMozambique, city: Maputo, country: Mozambique, geoPoint lat: -25.96553, lon: 32.58322, hasResults: False
protocolSection identificationModule nctId: NCT06326281, orgStudyIdInfo id: ACHBILKENT-ANEST-BK-01, briefTitle: Postoperative Pain Management in Laparoscopic Cholecystectomies, statusModule overallStatus: COMPLETED, startDateStruct date: 2023-07-01, primaryCompletionDateStruct date: 2024-02-22, completionDateStruct date: 2024-02-28, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Ankara City Hospital Bilkent, class: OTHER, descriptionModule briefSummary: This study is to demonstrate the effectiveness of external oblique intercostal plane block, a new block method, in the treatment of postoperative pain occurring after laparoscopic cholecystectomy operations, which are frequently and widely performed today.It aims to add new applications to multimodal analgesia methods, which provide the greatest contribution to the early recovery process after surgery, and to contribute to the early recovery process by increasing patient satisfaction., conditionsModule conditions: Cholecystitis/Cholelithiasis, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, interventionModelDescription: Evaluation of postoperative pain in 4 groups in laparoscopic cholecystectomy with control group, primaryPurpose: TREATMENT, maskingInfo masking: DOUBLE, maskingDescription: Patients were not told which method would be used The person evaluating the patients did not know which method was applied to which patient., whoMasked: PARTICIPANT, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 100, type: ACTUAL, armsInterventionsModule interventions name: external oblique intercostal plane block group, interventions name: oblique subcostal TAP block group, interventions name: Local anesthetic infiltration group, interventions name: control group, outcomesModule primaryOutcomes measure: Visual Analogue Scale Score, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 65 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ankara Bılkent City Hospital, city: Ankara, zip: 06100, country: Turkey, geoPoint lat: 39.91987, lon: 32.85427, hasResults: False
protocolSection identificationModule nctId: NCT06326255, orgStudyIdInfo id: LYASD, briefTitle: Feasibility and Acceptability of Laughter Yoga in Children With Autism Spectrum Disorder and Their Parents, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-03-15, primaryCompletionDateStruct date: 2024-10-01, completionDateStruct date: 2025-12-31, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: The Hong Kong Polytechnic University, class: OTHER, descriptionModule briefSummary: This is a pilot randomised controlled trial to explore the acceptability and feasibility of laughter yoga about anxiety and depression reduction in children with ASD and parenting stress reduction for their parents. Hypotheses of this study include:1. Laughter yoga is acceptable to children with ASD and their parents.2. Laughter yoga is feasible for anxiety and depression reduction in children with ASD and parenting stress reduction in their parents.3. Participants in the experimental group will have significantly more reduction in depression, anxiety and parental stress than those in the wait-list-control group., conditionsModule conditions: Autism Spectrum Disorder, conditions: Parenting Stress, conditions: Depression, conditions: Anxiety, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: PREVENTION, maskingInfo masking: NONE, enrollmentInfo count: 66, type: ESTIMATED, armsInterventionsModule interventions name: laughter yoga, outcomesModule primaryOutcomes measure: Response rate, primaryOutcomes measure: Attrition rate, primaryOutcomes measure: Attendance rate, primaryOutcomes measure: Perception on laughter yoga, primaryOutcomes measure: Difficulties in laughter yoga, primaryOutcomes measure: Safety issues, secondaryOutcomes measure: Depression, secondaryOutcomes measure: Anxiety, secondaryOutcomes measure: Parenting Stress, secondaryOutcomes measure: Child-parent Relationships, eligibilityModule sex: ALL, minimumAge: 8 Years, stdAges: CHILD, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The Hong Kong Polytechnic University, city: Hong Kong, country: Hong Kong, geoPoint lat: 22.27832, lon: 114.17469, hasResults: False
protocolSection identificationModule nctId: NCT06326242, orgStudyIdInfo id: IEO 1648, briefTitle: What Unmet Need for the Patients?A Focus on the Social Determinants of Health in Phase 1 Clinical Trials, statusModule overallStatus: RECRUITING, startDateStruct date: 2023-03-27, primaryCompletionDateStruct date: 2024-12-31, completionDateStruct date: 2024-12-31, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: European Institute of Oncology, class: OTHER, descriptionModule briefSummary: An observational prospective study of patients enrolled and treated with experimental drugs in Phase I studies., conditionsModule conditions: Solid Tumor, designModule studyType: OBSERVATIONAL, designInfo observationalModel: OTHER, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Solid Tumor, outcomesModule primaryOutcomes measure: The geographical accessibility of patients attending the Phase 1 facility of the European Institute of Oncology (IEO)., secondaryOutcomes measure: The characterization of enrolled patients involves assessing their participation in clinical trials, secondaryOutcomes measure: The characterization of enrolled patients based on therapeutic compliance., secondaryOutcomes measure: The protocol prescriptions in relation to socioeconomic and geographical determinants., eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: European Institute of oncology, status: RECRUITING, city: Milano, zip: 20141, country: Italy, contacts name: Teresa Profeta, role: CONTACT, phone: +390294372561, geoPoint lat: 45.46427, lon: 9.18951, hasResults: False
protocolSection identificationModule nctId: NCT06326229, orgStudyIdInfo id: CEIm 3096, briefTitle: Clinical Validation of Musculoskeletal ICF Core Set in Primary Care Physiotherapy, statusModule overallStatus: NOT_YET_RECRUITING, startDateStruct date: 2024-05-06, primaryCompletionDateStruct date: 2025-01-31, completionDateStruct date: 2025-09-26, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-04-05, sponsorCollaboratorsModule leadSponsor name: University of Valladolid, class: OTHER, collaborators name: Castilla-León Health Service, descriptionModule briefSummary: The aim of this observational study is to validate the content of a tailored ICF core set for the management of musculoskeletal conditions in primary care physiotherapy services.The main question it aims to answer is:- Are the ICF entities included in the ICF Core Set under evaluation useful from a clinical point of view?Participants will evaluate the relevance of each ICF entity included in the ICF core set according to their musculoskeletal condition., conditionsModule conditions: Musculoskeletal Diseases, designModule studyType: OBSERVATIONAL, designInfo observationalModel: COHORT, timePerspective: CROSS_SECTIONAL, enrollmentInfo count: 385, type: ESTIMATED, armsInterventionsModule interventions name: ICF entities assessment, outcomesModule primaryOutcomes measure: ICF core set for post-acute musculoskeletal conditions (adapted version for primary care physiotherapy services), otherOutcomes measure: Sociodemographic data of the sample, eligibilityModule sex: ALL, minimumAge: 18 Years, maximumAge: 99 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Ólvega Primary Care Physiotherapy service, city: Ólvega, state: Soria, zip: 42110, country: Spain, contacts name: Héctor Hernández Lázaro, PhD, role: CONTACT, phone: +34976645480, phoneExt: 38229, email: hhernandezl@saludcastillayleon.es, geoPoint lat: 41.77901, lon: -1.98391, hasResults: False
protocolSection identificationModule nctId: NCT06326216, orgStudyIdInfo id: 19-011292, secondaryIdInfos id: NCI-2023-05221, type: REGISTRY, domain: CTRP (Clinical Trial Reporting Program), secondaryIdInfos id: 19-011292, type: OTHER, domain: Mayo Clinic Institutional Review Board, briefTitle: Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatment of Prostate Cancer, statusModule overallStatus: RECRUITING, startDateStruct date: 2020-06-10, primaryCompletionDateStruct date: 2025-07-01, completionDateStruct date: 2025-07-01, studyFirstPostDateStruct date: 2024-03-22, lastUpdatePostDateStruct date: 2024-03-22, sponsorCollaboratorsModule leadSponsor name: Mayo Clinic, class: OTHER, descriptionModule briefSummary: This study is being done to determine whether levels of prostate cancer derived extracellular vesicles from blood and urine specimens correlate with response to primary local treatment (surgery) in prostate cancer., conditionsModule conditions: Prostate Carcinoma, designModule studyType: OBSERVATIONAL, designInfo observationalModel: CASE_CONTROL, timePerspective: PROSPECTIVE, enrollmentInfo count: 100, type: ESTIMATED, armsInterventionsModule interventions name: Non-Interventional Study, outcomesModule primaryOutcomes measure: Levels of prostate cancer-derived extracellular vesicles (EVs) - radical prostatectomy, primaryOutcomes measure: Levels of prostate cancer-derived extracellular vesicles (EVs) - negative controls, primaryOutcomes measure: Correlation between prostate specific antigen (PSA) levels and prostate cancer-derived EVs, primaryOutcomes measure: Prostate cancer-derived EV levels, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Mayo Clinic in Rochester, status: RECRUITING, city: Rochester, state: Minnesota, zip: 55905, country: United States, contacts name: Clinical Trials Referral Office, role: CONTACT, phone: 855-776-0015, email: mayocliniccancerstudies@mayo.edu, contacts name: Eugene D. Kwon, M.D., role: PRINCIPAL_INVESTIGATOR, geoPoint lat: 44.02163, lon: -92.4699, hasResults: False