protocolSection identificationModule nctId: NCT06379490, orgStudyIdInfo id: CTA no: 2024-510572-20-00, secondaryIdInfos id: 2024-510572-20-00, type: CTIS, secondaryIdInfos id: P-2023-296, type: OTHER, domain: Privacy - Region Hovedstaden, briefTitle: Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-04-23, primaryCompletionDateStruct date: 2024-08-01, completionDateStruct date: 2025-09-01, studyFirstPostDateStruct date: 2024-04-23, lastUpdatePostDateStruct date: 2024-04-24, sponsorCollaboratorsModule leadSponsor name: Nordsjaellands Hospital, class: OTHER, descriptionModule briefSummary: To investigate the feasibility of the lateral infraclavicular plexus brachialis (LIC) block for acute closed reduction of distal radius fractures, the investigators will compare the pain-relieving and muscle-relaxing properties of the LIC block with short- and long-acting local anesthetics in different concentrations but at the same volume. In addition to motor and sensory blockade during repositioning, feasibility will also be assessed by other patient-related and block-related factors, as well as by factors related to the repositioning and plastering procedure., conditionsModule conditions: Distal Radius Fractures, conditions: Lidocaine, conditions: Ropivacaine, conditions: Fracture Dislocation, conditions: Closed Reduction of Fracture and Application of Plaster Cast, conditions: Colles' Fracture, designModule studyType: INTERVENTIONAL, phases: PHASE3, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: QUADRUPLE, whoMasked: PARTICIPANT, whoMasked: CARE_PROVIDER, whoMasked: INVESTIGATOR, whoMasked: OUTCOMES_ASSESSOR, enrollmentInfo count: 63, type: ESTIMATED, armsInterventionsModule interventions name: Ropivacaine 0.2% Injectable Solution, interventions name: Lidocaine epinephrine, interventions name: Ropivacaine 0.5% Injectable Solution, outcomesModule primaryOutcomes measure: Block success, otherOutcomes measure: Degree of sensory and motor blockade, otherOutcomes measure: Total duration of sensory blockade, otherOutcomes measure: Total duration of motor blockade, otherOutcomes measure: Pain intensity before block performance, otherOutcomes measure: Time to pain relief/lowest pain intensity, otherOutcomes measure: Pain intensity during closed reduction, otherOutcomes measure: Pain intensity during cast application, otherOutcomes measure: Time to pain breakthrough after the blockade has ended, otherOutcomes measure: Maximum pain intensity after the blockade has ended, otherOutcomes measure: Duration of maximum pain intensity after the blockade has ended, otherOutcomes measure: Amount of strong painkillers consumed by patients within 24 hours after closed reduction, otherOutcomes measure: Grading of closed reduction difficulty, otherOutcomes measure: Quality of closed reduction evaluated by X-ray imaging, otherOutcomes measure: Attempts used for closed reduction, otherOutcomes measure: Grading of casting difficulty, otherOutcomes measure: The patient's experience of the treatment, otherOutcomes measure: Occurence of adverse events (AE) and serious adverse events (SAE), eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: Copenhagen University Hospital - North Zealand, status: RECRUITING, city: Hillerød, zip: 3400, country: Denmark, contacts name: Anders K. Nørskov, PhD, role: CONTACT, phone: 48 29 74 59, phoneExt: +45, email: anders.kehlet.noerskov@regionh.dk, contacts name: Kai H. W. Lange, DMSc, role: CONTACT, phone: 48 29 42 52, phoneExt: +45, email: kai.henrik.wiborg.lange@regionh.dk, geoPoint lat: 55.92791, lon: 12.30081, hasResults: False