hackint0sh/New-Dataset huggingface dataset:
The main objective of this study was to analyse the relationship between cerebrovascular disease and CMD in patients with atherosclerotic coronary artery disease (CAD). conditions: Microcirculation conditions: Coronary Artery Disease conditions: Cerebrovascular Circulation studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED name: Coronary angiography measure: MACE measure: MACE measure: Cerebral microcirculation measure: Cerebral microcirculation sex: ALL minimumAge: 45 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College status: RECRUITING city: Beijing state: Beijing zip: 100000 country: China name: Weijing Wang, PhD role: CONTACT phone: +8601088326200 email: wangweijing99@163.com lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06368622 id: CDM10001814 briefTitle: Evolve China PMCF Study overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-11 date: 2031-08 date: 2024-04-16 date: 2024-04-16 name: Stryker Neurovascular class: INDUSTRY name: Stryker (Beijing) Healthcare Products Co., Ltd briefSummary: A prospective, multi-center, single-arm, open-label, observational post-market real-world registry. The expected duration of the study is 8 years (including up to 5-years' follow-up).
Each subject will be followed in accordance with the standard of care (SOC) at each participating hospital. conditions: Intracranial Aneurysm studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 500 type: ESTIMATED name: Surpass Evolve Flow Diverter System measure: Neurological death or disabling stroke measure: 100% occlusion without significant parent artery stenosis measure: Procedure- and device-related serious adverse events measure: Key neurological events measure: Procedural success measure: Device success measure: Re-sheathing success sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Xuanwu Hospital Capital Medical University city: Beijing state: Beijing country: China lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06368609 id: 2024-09 briefTitle: Preliminary Evaluation of Two Rapid Diagnostic Test Prototypes for Strongyloides Stercoralis Infection acronym: PROTOSS overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-05 date: 2024-05 date: 2024-04-16 date: 2024-04-18 name: IRCCS Sacro Cuore Don Calabria di Negrar class: OTHER briefSummary: Single center, no profit experimental study on sera available in the Tropica Biobank. conditions: Strongyloides Stercoralis Infection studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 100 type: ESTIMATED name: IgG RDT name: IgG4 RDT measure: RDTs IgG results: positive or negative measure: RDTs IgG4 results: positive or negative measure: Agreement between readers sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS Sacro Cuore Don Calabria hospital city: Negrar state: Verona zip: 37024 country: Italy name: Dora Buonfrate role: CONTACT email: dora.buonfrate@sacrocuore.it name: Dora Buonfrate role: PRINCIPAL_INVESTIGATOR lat: 45.52918 lon: 10.93899 hasResults: False
nctId: NCT06368596 id: 2024-04 briefTitle: ENDS (ENDometriosis & FuSobacterium) Unveiling the Contribution of Fusobacterium Infection to the Development of Endometriosis acronym: ENDS overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-10 date: 2025-10 date: 2024-04-16 date: 2024-04-16 name: IRCCS Sacro Cuore Don Calabria di Negrar class: OTHER briefSummary: This will be a clinical interventional longitudinal study, without pharmacological intervention/device evaluation.
The study is classified as interventional, as Fusobacterium detection is not part of the routine management of these patients; from the patients' point of view, participation in the study will involve the execution of additional vaginal and cervical swabs as additional procedure, while the endometrial biopsy will not represent an additional examination, as the study will include only patients for whom this examination is expected as per normal clinical practice. conditions: Endometriosis studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: DIAGNOSTIC masking: NONE count: 845 type: ESTIMATED name: Fusobacterium detection measure: Fusobacterium sp presence (Y/N) in endometrial biopsy in women with endometriosis measure: Fusobacterium presence (Y/N) in endometrial biopsy in women without endometriosis measure: Fusobacterium presence (Y/N) in vaginal and cervical swab in all women enrolled measure: Fusobacterium presence (Y/N) in endometrial biopsy in women with and without PID complicating endometriosis . measure: Fusobacterium presence (Y/N) in biopsies of endometrial tissue involving different sites (superficial lesions, deep endometriosis, ovarian endometrioma), if present measure: Fusobacterium presence (Y/N) in endometrial biopsy in women with and without infertility associated to endometriosis measure: Fusobacterium presence (Y/N) in endometrial biopsy in women with and without hysteroscopic signs of chronic endometritis in patients with and without endometriosis sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS Sacro Cuore Don Calabria di Negrar city: Negrar state: Verona country: Italy name: Marcello Ceccaroni, Doctor role: CONTACT email: marcello.ceccaroni@sacrocuore.it role: CONTACT phone: 0456013111 name: Marcello Ceccaroni role: PRINCIPAL_INVESTIGATOR name: Dora Buonfrate role: SUB_INVESTIGATOR lat: 45.52918 lon: 10.93899 hasResults: False
nctId: NCT06368583 id: 24-05 briefTitle: The Patient AS EDUcator in Anesthesia: Exploring the Patients' and Providers' Experience During Neuraxial Labour Analgesia acronym: PAS-EDU-NLA overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-12 date: 2024-12 date: 2024-04-16 date: 2024-04-23 name: Samuel Lunenfeld Research Institute, Mount Sinai Hospital class: OTHER briefSummary: During the process of labour and delivery, patients may experience a wide range of events in a short time frame. This study focuses on exploring these experiences and aims to incorporate the improvements from these experiences so that in future, the expectations of patients delivering can be met as much as possible. Since every patient and encounter is unique, they might have a variety of experiences, be it during the labour epidural placement or during the delivery of the baby. Our study aims to explore the patients' perspective and learn about their preferences, concerns and suggestions regarding their experience and to then use this information to enhance the quality of future anesthesia care during labour and delivery.
Patients who underwent labour and delivery and received labour epidural for pain management will be approached the day following the delivery, while their recollection of their experience is still fresh, and given the opportunity to participate in the study which will involve the completion of a questionnaire as well as an interview lasting approximately 20-25 minutes. In addition to interviewing the patients, the study will also involve several interviews of the obstetricians, anesthesiologists, and nurses with the goals of seeing how the patients' experiences compare to the providers' perspective of the care they are delivering. Following the gathering of this information and identification of potential improvements in current practice, a follow up study will be performed aiming to implement changes and improve the quality of anesthesia care during labour and delivery. conditions: Well-Being, Psychological studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30 type: ESTIMATED name: Interview measure: Patient questionnaire measure: Patient interview sex: FEMALE minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Mount Sinai Hospital city: Toronto state: Ontario zip: M5G1X5 country: Canada name: Sabine Nabecker, MD role: CONTACT phone: 416-586-4800 phoneExt: 5270 email: sabine.nabecker@sinaihealth.ca name: Ron George, MD role: SUB_INVESTIGATOR name: Kristi Downey, MSc role: SUB_INVESTIGATOR name: Sunti Barahi, MD role: SUB_INVESTIGATOR name: Ratesh Bassi, MD role: SUB_INVESTIGATOR name: Afsheen Nasir, MD role: SUB_INVESTIGATOR lat: 43.70011 lon: -79.4163 hasResults: False
nctId: NCT06368570 id: 24-04 briefTitle: The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During Routine Cesarean Delivery acronym: PAS-EDU-RCD overallStatus: RECRUITING date: 2024-04-25 date: 2024-12 date: 2024-12 date: 2024-04-16 date: 2024-04-26 name: Samuel Lunenfeld Research Institute, Mount Sinai Hospital class: OTHER briefSummary: This study aims to explore the experience that the patient has as they undergo a routine Cesarean Delivery (CD). The indication for undergoing a routine CD varies amongst patients, but usually there is either an obstetric or medical reason for requiring a planned delivery of an infant via CD. Similarly, the experience of the CD varies significantly between patients as there are many patient, surgical and anesthetic factors that interact to create the unique experience each patient has. This study aims to explore the patients' perspective and learn about their preferences, concerns and suggestions regarding their experience of CD and to then use this information to enhance the quality of future anesthesia care for elective CD.
Patients who have undergone a routine CD will be approached the day following their delivery, while their recollection of their experience is still fresh, and given the opportunity to participate in the study, which will involve the completion of a questionnaire as well as an interview lasting approximately 20-25 minutes. In addition to interviewing the patients, the study will also involve several interviews of obstetricians, anesthesiologists and nurses with the goal of seeing how the patients' experiences compare to the providers' perspective of the care they are delivering. Following the gathering of this information and identification of potential improvements in current practice a follow up study will be performed aiming to implement changes and improve the quality of anesthesia care during elective CD. conditions: Well-Being, Psychological studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30 type: ESTIMATED name: Interview measure: Patient questionnaire measure: Patient interview sex: FEMALE minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Mount Sinai Hospital status: RECRUITING city: Toronto state: Ontario zip: M5G1X5 country: Canada name: Sabine Nabecker, MD role: CONTACT phone: 416-586-4800 phoneExt: 5270 email: sabine.nabecker@sinaihealth.ca name: Ron George, MD role: SUB_INVESTIGATOR name: Kristi Downey, MSc role: SUB_INVESTIGATOR name: Fernanda Septimio Lanza Oliveira, MD role: SUB_INVESTIGATOR name: Lada Kordich, MD role: SUB_INVESTIGATOR name: Afsheen Nasir, MD role: SUB_INVESTIGATOR lat: 43.70011 lon: -79.4163 hasResults: False
nctId: NCT06368557 id: 22/59602 briefTitle: Internet-based Cognitive Behavioral Intervention for Adolescents With Anxiety Disorders overallStatus: RECRUITING date: 2023-10-10 date: 2025-03 date: 2025-06 date: 2024-04-16 date: 2024-04-16 name: Region of Southern Denmark class: OTHER name: University of Aarhus briefSummary: The goal of the randomized controlled trial is to find out if the internet-based therapy (iCBT) intervention CoolMinds, is effective in helping adolescents with anxiety. The adolescents in the study are aged between 12 and 17 years of age, who live in the region of Southern Denmark. They must have an anxiety diagnosis according to the
nctId: NCT06368544 id: M2023816 briefTitle: Effect of Early Gait Training on Knee Cartilage Degeneration After Anterior Cruciate Ligament Reconstruction overallStatus: RECRUITING date: 2024-01-07 date: 2030-02-07 date: 2030-02-07 date: 2024-04-16 date: 2024-04-16 name: Peking University Third Hospital class: OTHER briefSummary: A randomized controlled clinical study was conducted to elucidate the relationship between the lower extremity biomechanics of patients undergoing early gait training after ACLR surgery.The relationship between the biochemical characteristics of cartilage and the biomechanical risk index were proposed to providing exercise guidance and training for middle-aged people and it is suggested that it can prevent and reduce the risk of cartilage degeneration early after operation. conditions: Anterior Cruciate Ligament Injuries conditions: Cartilage Degeneration studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 30 type: ESTIMATED name: lower-body positive-pressure measure: Gait biomechanical data measure: Gait biomechanical data measure: Gait biomechanical data measure: Gait biomechanical data measure: Gait biomechanical data measure: Biochemical characteristics of knee cartilage measure: Biochemical characteristics of knee cartilage sex: ALL minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: Peking University Third Hospital status: RECRUITING city: Beijing country: China name: ren shuang role: CONTACT phone: xixishuang123@126.com lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06368531 id: 2314270 briefTitle: Long-term Monitoring of Sleep With Ear-EEG in Patients With Chronic Pain overallStatus: RECRUITING date: 2024-04-04 date: 2025-02-15 date: 2025-08-15 date: 2024-04-16 date: 2024-04-16 name: Odense University Hospital class: OTHER name: University of Aarhus name: T&W Engineering A/S briefSummary: Insomnia is reported by more than 50% of patients with chronic pain. In this study, the investigators aim to advance the understanding of physiological sleep in individuals with chronic pain. To do this the investigators will monitor at-home sleep with an ear-EEG over 20 nights in patients with chronic pain and collect self-reported measures of sleep and pain. The collected data will be used to explore and characterize intra-individual variations in sleep metrics (e.g. total sleep time, time in each sleep stage (N1, N2, N3, REM), sleep latency, REM stage latency, wake after sleep onset, sleep efficiency, number of arousals and arousal index) over 20 nights. conditions: Chronic Pain conditions: Insomnia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 25 type: ESTIMATED measure: sleep period time (SPT) from Ear EEG measure: Qualitative sleep parameters obtained from sleep diary. measure: Pain intensity rating measure: Time from sleep onset until final awakening (TST) from Ear EEG measure: Sleep efficiency (SE) from Ear EEG measure: Sleep onset latency (SOL) from Ear EEG measure: Wake after sleep onset (WASO) from Ear EEG measure: REM sleep latency from Ear EEG measure: Time from sleep onset until first epoch of REM stage sleep from Ear EEG measure: Amount of wake and stage N1, N2, N3, and R sleep as a percentage of SPT from Ear EEG measure: Number of awakenings within TST from Ear EEG measure: Arousal index which is number of arousals per hour from Ear EEG measure: Ease-of-use and Comfort with ear EEG measure: Adverse device effects measure: Polysomnography measure: Sleep quality measure: Insomnia measure: The Graded Chronic Pain Scale Revised measure: Age measure: Sex measure: Ethnicity measure: Height measure: Weight measure: Level of education measure: Obstructive sleep apnea sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Pain Center, Department of Anesthesiology and Intensive Care Medicine, University Hospital Odense status: RECRUITING city: Odense zip: 5000 country: Denmark name: Henrik B Vaegter, PhD role: CONTACT phone: 004565413869 lat: 55.39594 lon: 10.38831 hasResults: False
nctId: NCT06368518 id: ID01/2024/MZHCM-Reg/NV briefTitle: Austrian HCM Registry overallStatus: RECRUITING date: 2024-03-08 date: 2034-03 date: 2034-03 date: 2024-04-16 date: 2024-04-16 name: Medical University of Graz class: OTHER briefSummary: The Austrian Hypertrophic Cardiomyopathy (HCM) Registry is a prospective, multicenter registry enrolling patients at multiple outpatient clinics across Austria including academic and non-academic centers. Patients will undergo a structured examination process including assessment for symptoms of HCM, past medical history, concomitant medication, family history and the presence of HCM-specific red flags. Furthermore, clinical data derived from electrocardiogram, echocardiography, laboratory analysis, and genetic testing will be collected focusing on a lean variable dictionary and, in addition, specific hypothesis-driven research parameters. All data are entered into an electronic case report form (eCRF) (Phoenix Clinical Trial Management System). In order to perform multicenter analyses, data can be extracted from the eCRF after approval by the steering committee. conditions: Hypertrophic Cardiomyopathy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 200 type: ESTIMATED measure: All cause mortality measure: Cardiovascular events sex: ALL minimumAge: 18 Years maximumAge: 100 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Medical University of Graz status: RECRUITING city: Graz state: Styria zip: 8036 country: Austria name: Nicolas Verheyen, MD, PHD role: CONTACT phone: 004331638530173 email: nicolas.verheyen@medunigraz.at name: Viktoria Santner, MD role: CONTACT email: viktoria.santner@medunigraz.at name: Nicolas Verheyen, MD, PHD role: PRINCIPAL_INVESTIGATOR lat: 47.06667 lon: 15.45 hasResults: False
nctId: NCT06368505 id: R.24.02.2506.R1 briefTitle: Platelet-Rich Plasma Injection Versus Hydrodissection in the Treatment of Carpal Tunnel Syndrome overallStatus: RECRUITING date: 2024-01-16 date: 2024-06-16 date: 2024-07-16 date: 2024-04-16 date: 2024-04-16 name: Osama Ahmed Elshafei class: OTHER briefSummary: The goal of this clinical trial is to compare the efficacy of Ultrasound-Guided Platelet-Rich Plasma Injection versus Hydrodissection (using 2ml saline, 2ml dexamethasone and 1ml lidocaine) in the Treatment of Carpal Tunnel Syndrome. The main questions it aims to answer are:
* Assessed for efficacy and safety of the intervention conditions: Carpal Tunnel Syndrome studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 64 type: ESTIMATED name: ultrasound guided PRP injection name: ultrasound guided hydrodissection measure: Boston Carpal Tunnel Syndrome Questionnaire (BCTQ) measure: The visual analog scale (VAS) measure: The cross-sectional area (CSA) of the Median nerve sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mansoura University status: RECRUITING city: Mansoura zip: 35511 country: Egypt name: osama elshafei, MD PHD role: CONTACT email: osama_elshafei@mans.edu.eg name: Dena El-Ghzzawy role: CONTACT email: Profdr_os@yahoo.com name: Dena El-Ghzzawy, MD role: SUB_INVESTIGATOR name: OSAMA ELSHAFEI, MD PHD role: PRINCIPAL_INVESTIGATOR lat: 31.03637 lon: 31.38069 hasResults: False
nctId: NCT06368492 id: P137 id: 2021-002909-10 type: EUDRACT_NUMBER id: NL78008.068.21 type: OTHER domain: METC azM/Maastricht University briefTitle: The Impact of Psilocybin on Pain in Fibromyalgia Patients acronym: PsiloFM overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-12 date: 2025-12 date: 2024-04-16 date: 2024-04-16 name: Maastricht University class: OTHER name: Leiden University Medical Center briefSummary: Rationale: Recent evidence shows that Lysergic Acid Diethylamide (LSD), even when administered in low, non-hallucinogenic doses, can produce analgesic effects and improve pain tolerance in a sample of healthy volunteers. Such results complement what was already observed with other serotonergic psychedelics such as psilocybin: survey studies and case series indicate that its use may lead to improvements in chronic pain conditions such as migraines, cluster headaches and phantom limb pain even at low, non-psychedelic doses. These effects have however not yet been investigated and confirmed in clinical populations under controlled experimental conditions.
Study design: The present study uses a double-blind, randomized, placebo-controlled design. All participants will receive a placebo and 2 doses of psilocybin (5 mg or 10 mg) and will undergo the Cold Pressor Test (CPT) and the Pain Pressure Threshold Task (PPT) o test its analgesic effects. conditions: Fibromyalgia studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: double-blind, randomized, within-subjects, placebo-controlled design. primaryPurpose: TREATMENT masking: NONE maskingDescription: Blinding will be handled by one of the study pharmacies and order and allocation of the treatment to each participant will be completely randomized. This setup ensures that neither the participant nor the experimenter running the test day will be aware of the contents of the capsule. count: 35 type: ESTIMATED name: Psilocybin name: Hypnosis script measure: Ischemic Pain perception measure: Pressure-evoked Pain perception measure: Self-reported pain measure: Subjective effects: psychedelic phenomenology measure: Subjective effects: mood measure: Subjective effects: intensity of effects measure: Subjective effects: Ego dissolution measure: Subjective effects: Dissociation measure: Psychiatric symptoms measure: Cognitive performance measure: Vigilance measure: Empathy measure: Creativity measure: Creativity measure: Autobiographical memory measure: Autobiographical memory measure: Treatment expectancy measure: Treatment expectancy measure: Fibromyalgia-related pain measure: Personality measure: Absorption measure: Interpersonal Reactivity measure: Depression sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Maastricht University city: Maastricht state: Limburg zip: 6226AK country: Netherlands name: Mauro Cavarra, MSc role: CONTACT phone: +313494438261 email: m.cavarra@maastrichtuniversity.nl lat: 50.84833 lon: 5.68889 facility: Leiden University Medical Center city: Leiden state: South Holland zip: 2333 country: Netherlands name: Monique van Velzen, PhD role: CONTACT email: M.van_Velzen@lumc.nl lat: 52.15833 lon: 4.49306 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2023-09-08 uploadDate: 2023-10-30T07:36 filename: Prot_SAP_000.pdf size: 673739 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2023-10-10 uploadDate: 2023-10-30T07:38 filename: ICF_001.pdf size: 451492 hasResults: False
nctId: NCT06368479 id: CLS-016B briefTitle: A Prospective Cross-Sectional Study to Evaluate Diagnostic Sensitivity and Specificity of iStatis HBsAg Test at the Point-Of-Care Site Settings overallStatus: RECRUITING date: 2024-03-20 date: 2024-07-01 date: 2024-07-01 date: 2024-04-16 date: 2024-04-16 name: bioLytical Laboratories class: INDUSTRY briefSummary: A prospective cross-sectional study in which surgically non-invasive sample-taking is done only for the purpose of testing the samples on iStatis HBsAg Test at the point of care. conditions: Hepatitis B conditions: Hepatitis B Infection studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SCREENING masking: DOUBLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 4400 type: ESTIMATED name: iStatis HBsAg Test measure: iStatis Performance sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Epicentre Health Research status: RECRUITING city: Hillcrest state: Kwazulu Natal zip: 3650 country: South Africa name: Cherie Cawood role: CONTACT phone: +27828202955 email: cheriec@epicentre.org.za hasResults: False