hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06378905 id: 141/57 briefTitle: Cukurova Score Validation Study acronym: CUKUROVA overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-03 date: 2027-03 date: 2024-04-23 date: 2024-04-23 name: Cukurova University class: OTHER name: Muğla Sıtkı Koçman University name: Sakarya University name: Gazi University name: Ankara Etlik City Hospital name: Kayseri City Hospital name: Mersin University name: Selçuk University name: Bezmialem Vakif University name: Uludag University name: Mersin City Hospital name: Marmara University name: Prof. Dr. Cemil Tascıoglu City Hospital name: Ankara University name: Ege University name: Hacettepe University name: Akdeniz University name: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital name: Mustafa Kemal University name: Trakya University briefSummary: Despite significant advancements in imaging technologies, surgical techniques, chemotherapeutic regimens, and treatment strategies in recent years, ovarian cancer continues to remain the most deadly gynecological malignancy. Approximately 90% of ovarian cancers originate from the coelomic epithelium or modified mesothelial cells and are classified as epithelial ovarian cancers. The majority of patients with epithelial ovarian cancer (70-80%) present in advanced stages. The primary treatment for advanced-stage (stage 3-4) disease consists of primary cytoreductive surgery followed by adjuvant chemotherapy. Cytoreductive surgery aims to remove all visible tumor implants regardless of the extent of the disease and achieve no visible residual tumor (complete cytoreduction, R0) at the end of the surgery. In cases where R0 cannot be achieved (due to poor general condition and/or extensive tumor that cannot be completely excised surgically), the option of neoadjuvant chemotherapy followed by interval cytoreductive surgery is considered. Primary cytoreductive surgery is still the preferred option and is considered a quality indicator for centers performing advanced-stage ovarian cancer surgeries. Despite advancements in surgery, the decision for interval surgery following primary surgery or neoadjuvant chemotherapy is often based on the surgeon's experience, imaging results, and clinic preferences. Various methods and scores have been published and applied to predict which patients are suitable for primary surgery.
The Cukurova score developed in our clinic conceptualizes prioritizing surgical procedures using radiological imaging and diagnostic exploratory laparoscopy to achieve complete cytoreduction in harmony with the patient's clinical and performance status, rather than focusing solely on tumor burden. The score showed high success rates for complete cytoreduction and also was useful in terms of predicting the morbidity and mortality. However, the Cukurova score study was conducted in single center. Validation of scores in centers with different capacities is expected to facilitate their widespread use and acceptance. Therefore, in this study, the investigators plan to conduct a validation study of the score in a total of 20 centers in Turkey, including our center. This study aims to evaluate the validity of the Cukurova score in predicting outcomes of primary cytoreduction in advanced ovarian cancer patients and thus determining the decision for primary cytoreductive surgery or neoadjuvant chemotherapy followed by interval cytoreductive surgery. conditions: Epithelial Ovarian Cancer conditions: Primary Cytoreduction studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 130 type: ESTIMATED measure: Rate of complete cytoreduction measure: Rate of postoperative 90-days mortality measure: Rate of postoperative morbidity sex: FEMALE minimumAge: 18 Years maximumAge: 100 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Cukurova University city: Adana zip: 01330 country: Turkey name: Ghanim Khatib, MD role: CONTACT phone: 03223386060 email: ghanim.khatib@gmail.com name: Ghanim Khatib, MD role: CONTACT phone: +903223386060 phoneExt: Khatib email: ghanim.khatib@gmail.com name: Ghanim Khatib, MD,Ass.Prof role: PRINCIPAL_INVESTIGATOR lat: 37.00167 lon: 35.32889 hasResults: False
nctId: NCT06378879 id: 1073/1/3/26 briefTitle: Intermittent Boluses Versus Infusion of Propofol During Gastroscopy overallStatus: NOT_YET_RECRUITING date: 2024-05-06 date: 2025-04-30 date: 2025-07-30 date: 2024-04-23 date: 2024-04-23 name: Al-Balqa Applied University class: OTHER name: Luzmila Hospital briefSummary: It is unclear whether continuous infusion or intermittent bolus injection of propofol is better for achieving adequate sedation during a standard upper endoscopy. The study aimed to compare the efficacy and safety of continuous infusion and intermittent bolus injection of Propofol (Diprivan) during a standard upper endoscopy. In this prospective study, patients will be randomly assigned to undergo a standard upper endoscopy with either continuous infusion (CI group) or intermittent bolus injection (BI group) of Propofol (Diprivan) administered by an anesthesiologist. The primary outcome will be to assess the quality of sedation by the endoscopist (VAS). In addition to other sedation-related parameters that will include sedation induction time (minutes), total dose of propofol (mg), recovery time (minutes) using Aldrete score, any involuntary patient movement, and adverse events. conditions: Anesthesia studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 100 type: ESTIMATED name: Propofol 100 MG in 10 ML Injection measure: Sedation induction time (minutes) measure: Total dose of propofol (mg) measure: Recovery time (minutes) measure: Involuntary movement measure: Quality of sedation measure: Adverse events sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06378853 id: 2023DZKY-049-01 briefTitle: Risk Factors of Postoperative Complications and Survival Rate in Pancreatic Ductal Adenocarcinoma Patients overallStatus: COMPLETED date: 2019-01-01 date: 2023-12-31 date: 2024-02-28 date: 2024-04-23 date: 2024-04-23 name: Jinling Hospital, China class: OTHER briefSummary: By evaluating the nutritional status of patients with pancreatic ductal adenocarcinoma (PDAC) admitted to Jinling Hospital, collecting relevant clinical data. we aim to conduct correlation analysis with patient clinical information, such as survival time, hospitalization time, nutritional status, hematological indicators, etc., in order to reveal the prognostic factors for overall survival and postoperative complications of PDAC patients. conditions: Pancreatic Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 548 type: ACTUAL name: no intervention measure: complications measure: overall survival measure: risk factors sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Jinling Hospital city: Nanjing country: China lat: 32.06167 lon: 118.77778 hasResults: False
nctId: NCT06378840 id: KY2021-268-B briefTitle: the Predictive Value of Immune Cell in Locally Advanced Cervical Cancer overallStatus: RECRUITING date: 2022-01-01 date: 2024-12-30 date: 2024-12-30 date: 2024-04-23 date: 2024-04-23 name: RenJi Hospital class: OTHER briefSummary: To explore the predictive value of immune cells by single-cell sequencing on the outcome of locally advanced cervical cancer treated by concurrent chemoradiotherapy Followed by PD-1 inhibitor conditions: Locally Advanced Cervical Carcinoma conditions: Concurrent Chemoradiotherapy conditions: Immunotherapy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 20 type: ESTIMATED name: Nab-paclitaxel/Platinum, Sintilimab measure: the change of immune cells in the blood after chemoradiotherapy and immunotherapy measure: the predictive value of the changed immune cell subtype in the blood on the side effect of immunotherapy measure: the predictive value of the changed immune cell subtype in the blood on the effect of chemoradiotherapy and immunotherapy measure: the change of immune cells in the tissue after chemoradiotherapy measure: the predictive value of the changed immune cell subtype in the tissue on the effect of chemoradiotherapy and immunotherapy measure: the predictive value of the changed immune cell subtype in the tumor microenvironment on the side effect of immunotherapy sex: FEMALE minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: RenJi hospital status: RECRUITING city: Shanghai zip: 200127 country: China name: Haiyan Chen, Dr role: CONTACT phone: +862168383624 email: chenhaiyan@renji.com lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06378827 id: 418-1/2 briefTitle: Intraoperative Dexmedetomidine and Coronary Artery Bypass Graft Surgery overallStatus: RECRUITING date: 2024-04-03 date: 2024-07 date: 2024-10 date: 2024-04-23 date: 2024-04-23 name: University of Novi Sad class: OTHER briefSummary: This is a prospective randomized clinical trial designed to determine the effect of intraoperative dexmedetomidine administration on renal function after coronary artery bypass graft surgery. conditions: Acute Kidney Injury studyType: INTERVENTIONAL phases: PHASE2 phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: DOUBLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 100 type: ESTIMATED name: Dexmedetomidine measure: Indicator of renal function measure: An early biomarker of kidney injury measure: The change of inflammatory markers measure: Length of postoperative mechanical ventilation measure: Length of stay in the intensive care unit sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Novi Sad, Faculty of Medicine status: RECRUITING city: Novi Sad zip: 21000 country: Serbia name: Ranko Zdravkovic role: CONTACT phone: +381654674620 email: ranko.zdravkovic@mf.uns.ac.rs lat: 45.25167 lon: 19.83694 hasResults: False
nctId: NCT06378814 id: IRAS N335444 briefTitle: Outcome of Selective & Nonselective Caries Removal in Permanent Teeth acronym: RCT-SNCR overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-04-30 date: 2030-04-30 date: 2024-04-23 date: 2024-04-29 name: King's College London class: OTHER name: Guy's and St Thomas' NHS Foundation Trust briefSummary: Patients presenting with deep decay within permanent teeth presents a common clinical challenge to dentists. The aim of this trial is to compare the success rate of the non-selective caries removal (NSCR) and selective caries removal (SCR) in managing deep caries, as both methods are commonly used in clinical practice.
This study will be a randomized controlled trial, with participants divided into two groups: NSCR group and SCR group. Participants of deep caries lesions (reaching more than two-thirds of dentin on periapical radiographs) Both groups will undergo either NSCR or SCR, followed by Partial Pulpotomy (PP) in cases with pulp exposure. Success rates will be assessed at follow-up visits scheduled 1, 3, and 5 years radiographs will be used to assess for pulp health(vitality).
In conclusion, this trial aims to compare the success rate of NSCR and SCR in managing deep caries lesions in permanent teeth, as both methods are commonly used in clinical practice. The results of this study will provide valuable insights into the effectiveness of these two treatment approaches and will help clinicians to make informed decisions when choosing the appropriate treatment approaches. conditions: Deep Caries conditions: Carious Exposure of Pulp studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: two arms parallel randomized clinical trial primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 168 type: ESTIMATED name: Selective Caries Removal (No Pulp Exposure) name: Non-Selective Caries Removal (No Pulp exposure) name: Partial Pulpotomy (Pulp Exposed) measure: To compare the success rate of maintaining pulp vitality assessed by pulp sensibility test between Selective Caries Removal or Non- Selective Caries Removal techniques after one year of the intervention. measure: Periapical Health Assessment Using Periapical Index Score in Deep Caries Lesion Treatment measure: Quality of Life Assessment ( Using OHIP-14 questionnaire) in Deep Caries Lesion Treatment: A Comparative Study of Selective Caries Removal and Partial Pulpotomy sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06378801 id: RADX-P-2408 briefTitle: Radicle Relaxation 24: A Study of Health and Wellness Products on Stress and Related Health Outcomes overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-29 date: 2024-05 date: 2024-08 date: 2024-04-22 date: 2024-04-24 name: Radicle Science class: INDUSTRY briefSummary: A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on stress and related health outcomes conditions: Stress studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Participants will be stratified based on gender at birth, then randomized to one of the study arms primaryPurpose: OTHER masking: DOUBLE maskingDescription: The investigator is blinded to the participants' study product assignment. Participants are blinded to the study product they are assigned. whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 500 type: ACTUAL name: Placebo Control Form 1 name: Relaxation Active Study Product 1.1 measure: Change in stress measure: Change in feelings of anxiety measure: Change in cognitive function measure: Change in mood (emotional distress-depression) measure: Minimal clinically important difference (MCID) in stress measure: Minimal clinically important difference (MCID) in feelings of anxiety measure: Minimal clinically important difference (MCID) in cognitive function measure: Minimal clinically important difference (MCID) in mood (emotional distress-depression) measure: Change in concentration of at-home (direct-to-consumer) specimen assays either saliva, blood or stool sex: ALL minimumAge: 21 Years maximumAge: 105 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Radicle Science, Inc city: Del Mar state: California zip: 92014 country: United States lat: 32.95949 lon: -117.26531 hasResults: False
nctId: NCT06378788 id: 2023/211 briefTitle: Muscle Architecture and Muscle Strength in Fibromyalgia overallStatus: RECRUITING date: 2024-02-01 date: 2024-04-30 date: 2024-06-30 date: 2024-04-22 date: 2024-04-25 name: Bezmialem Vakif University class: OTHER briefSummary: The goal of this observational study is to determine whether there is decrease in muscle mass and muscle strength in Fibromyalgia Syndrome (FMS) patients in comparison to controls. And to determine whether these parameters are correlated with clinical ones. Briefly the main questions investigators aims to answer are:
* Is there a correlation between muscle strength in FMS and disease activity, pain and functionality? conditions: Fibromyalgia conditions: Sarcopenia conditions: Muscle Weakness studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: CROSS_SECTIONAL count: 30 type: ESTIMATED name: Demographic information form name: widespread pain index (WPI) name: symptom severity scale (SSS) name: Fibromyalgia Impact Questionnaire (FIQ) name: Tender Point examination name: Muscle Architecture visualized with ultrasound name: Sarcopenia assessed by measuring isometric strengths of different parts of the body name: Timed Up & Go (TUG) measure: Quadriceps Femoris Vastus Lateralis Muscle Thickness measure: Quadriceps Femoris Vastus Lateralis Fascicle Length measure: Quadriceps Femoris Vastus Medialis Muscle Thickness measure: Quadriceps Femoris Vastus Medialis Fascicle Length measure: Quadriceps Femoris Rectus Femoris Muscle Thickness measure: Quadriceps Femoris Rectus Femoris Fascicle Length measure: Tibialis Anterior Muscle Thickness measure: Tibialis Anterior Muscle Fascicle Length measure: Gastrocnemius Muscle Vastus Medialis Muscle Thickness measure: Gastrocnemius Muscle Vastus Medialis Fascicle Length measure: Gastrocnemius Muscle Vastus Lateralis Muscle Thickness measure: Gastrocnemius Muscle Vastus Lateralis Fascicle Length measure: Cervical Muscle strength measure: Truncal Muscle strength measure: Shoulder Muscle strength measure: Hip Muscle strength measure: Knee Muscle strength measure: Ankle Muscle strength measure: Timed Up & Go (TUG) sex: FEMALE minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Bezmialem Vakif University status: RECRUITING city: Istanbul state: Fatih zip: 34093 country: Turkey name: Mehmet Serkan Kılıçoğlu, Ass.Prof. role: CONTACT phone: +902124530453 email: drserkankilicoglu@yahoo.com name: Delal Ozturk, Res.Ass. role: CONTACT phone: +902124530453 email: drdelalozturk@gmail.com lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06378775 id: H23-03334 briefTitle: Robotically-assisted Minimally-invasive Direct Coronary Artery Bypass With Stenting, Randomized Against Coronary Artery Bypass Graft Surgery acronym: ROBOT RCT overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-05-01 date: 2028-12-01 date: 2024-04-22 date: 2024-04-23 name: Cardiology Research UBC class: OTHER briefSummary: The study objective is to compare standard CABG to a hybrid revascularization strategy (RA-MIDCAB + PCI) in patients who have multi-vessel CAD and an indication for surgery, but who have a slightly higher risk of post-operative complications. conditions: Coronary Artery Disease conditions: Multivessel Coronary Artery Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 80 type: ESTIMATED name: Coronary Artery Bypass Graft name: Robotically-assisted minimally-invasive direct coronary artery bypass name: Percutaneous Coronary Intervention measure: Post-operative Length of Stay measure: Conversion to sternotomy / CABG measure: Intubation duration measure: ICU length of stay sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06378762 id: 6/2021 briefTitle: Interference of Endurance Training on Strength Development and Neuromuscular Adaptations overallStatus: ACTIVE_NOT_RECRUITING date: 2022-04-01 date: 2024-07-30 date: 2025-07-30 date: 2024-04-22 date: 2024-04-22 name: University of Lisbon class: OTHER name: Fundação para a Ciência e a Tecnologia briefSummary: This study aims to find out if performing combined strength and endurance exercise in the same program (called concurrent training-CT) leads to similar long-term improvements in neuromuscular function as doing each type of exercise separately. The main questions it seeks to answer are:
Does performing CT result in similar improvements in strength and power as doing just strength training? Does performing CT result in similar improvements in cardiorespiratory fitness as doing just endurance training? Are neuromuscular adaptations similar between CT and just strength training? Researchers will compare the results between three groups: the CT group, the endurance training group (E), and the strength training group (S) to answer these questions. conditions: Exercise studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 30 type: ACTUAL name: Endurance Exercise name: Strength Exercise name: Concurrent Exercise measure: Maximal Isometric Strength measure: Maximal Dynamic Strength measure: Surface EMG measure: H-reflex excitability measure: V-wave measure: Lower Body Muscle Power measure: Muscle architecture of the quadriceps femoris sex: MALE minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT facility: Faculdade de Motricidade Humana - Universidade de Lisboa city: Lisboa state: Cruz Quebrada - Dafundo zip: 1499-002 country: Portugal lat: 38.71667 lon: -9.13333 hasResults: False
nctId: NCT06378736 id: 21-1027 briefTitle: Electroencephalogram Recording in Patients With Systemic Lupus Erythematosus overallStatus: RECRUITING date: 2024-01-22 date: 2026-03-23 date: 2026-03-23 date: 2024-04-22 date: 2024-04-29 name: Northwell Health class: OTHER briefSummary: Patients with systemic lupus erythematosus (SLE) often experience a frustrating decline of their cognitive skills that includes considerable problems in attention, learning, and memory. This lupus-related cognitive dysfunction (termed SLE-CD) is recognized as the most prevalent of the nineteen neuropsychiatric SLE syndromes, as it affects up to 80% of patients and can significantly decrease their quality of life. The goal is to have tools that can be used for diagnosis and for monitoring responses after targeted interventions and therapies. This study will focus on electroencephalographic (EEG) signals, which will be detected noninvasively from scalp placed surface electrodes while the subjects are in a state of wakeful rest. Our hypothesis is that a subset of brain oscillations known as theta and gamma, and their co-modulation or coupling will be disrupted in SLE patients. This research protocol will subject patients with systemic lupus erythematosus (SLE) to scalp electroencephalography (EEG), with the goal of determining whether specific EEG patterns ('theta-gamma coupling') appear abnormal during wakeful-rest periods of 20 minutes. The investigators are interested in using scalp EEG because it is a standard, safe and robust technique for monitoring the electrophysiological activity of neurons in the cerebral cortex. conditions: Systemic Lupus Erythematosus studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 40 type: ESTIMATED name: Electroencephalography (EEG) signals, which will be detected noninvasively from dry scalp surface electrodes while the subjects are in a state of wakeful rest. measure: A measure of the amount and relationship of theta and gamma waves in the EEG recording. The ability to perform the block building task and the ability to choose among unfolded three-dimensional objects. sex: FEMALE minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Northwell Health-Feinstein Insitute status: RECRUITING city: Manhasset state: New York zip: 11030 country: United States name: Bruce T Volpe, MD role: CONTACT phone: 516-562-3384 email: bvolpe1@northwell.edu name: Celina B. Fernandez, MS role: CONTACT phone: 5165623646 email: cfernandez14@northwell.edu lat: 40.79788 lon: -73.69957 hasResults: False
nctId: NCT06378723 id: 2024/01/24 briefTitle: The Relationship Between Upper Extremity Functionality, Trunk Control and Balance in Children With Cerebral Palsy overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-01 date: 2024-04-15 date: 2024-04-16 date: 2024-04-22 date: 2024-04-23 name: Eastern Mediterranean University class: OTHER briefSummary: The aim of this study is to examine the relationship between trunk control, upper extremity functionality and balance in children with cerebral palsy and to compare this relationship with healthy sedentary children.This study is carried out through Eastern Mediterranean University Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Pediatric Rehabilitation Unit. conditions: Cerebral Palsy conditions: Diplegic Cerebral Palsy conditions: Balance; Distorted studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: OTHER count: 53 type: ACTUAL name: Balance Tests measure: trunk control measure: upper extremity functionality measure: balance measure: Weight and Height sex: ALL minimumAge: 8 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Eastern Mediterranean University city: Famagusta zip: 99628 country: Cyprus lat: 35.12054 lon: 33.93894 facility: Yeni Sihirli Eller Özel Eğitim ve Rehabilitasyon Merkezi city: Adana state: Çukurova zip: 01170 country: Turkey lat: 37.00167 lon: 35.32889 hasResults: False