hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06371625 id: AP2202-30104 briefTitle: U/S Guided Transversus Thoracic and Pectoral Nerve Block Versus Pectoral Nerve Block in MRM overallStatus: COMPLETED date: 2022-07-02 date: 2023-08-01 date: 2023-10-01 date: 2024-04-17 date: 2024-04-22 name: Ahmed Mohamed Soliman class: OTHER briefSummary: Interfascial blocks score over regional anesthetic techniques such as Transversus Thoracic Plane Block and Pectoral Nerves (PECS) Block as they have no risk of sympathetic blockade, intrathecal or epidural spread, which may lead to hemodynamic instability and prolonged hospital stay. The transversus thoracic muscle plane block (TTP) block is a newly developed regional anesthesia technique which provides analgesia to the anterior chest wall. First described by Ueshima et al. in 2015, the TTP block is a single-shot nerve block that deposits local anesthetic in the transversus thoracic muscle plane between the internal intercostal and transversus thoracic muscles. TTP block targets the anterior branches of the intercostal nerves (T2-6).
The pectoral nerves (PECS) block provides analgesia of the lateral mammary region, the intercostobrachial and lateral cutaneous branches of the intercostal nerves (T2-T6), the medial cutaneous nerve of the arm and forearm, and the long thoracic and thoracodorsal nerves. The modified PECS block produces excellent analgesia and can be used to provide balanced anesthesia. conditions: Breast Cancer conditions: Analgesia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: to determine the analgesic effect of ultrasound guided Transversus Thoracic and Pectoral Nerve Block compared to ultrasound guided Pectoral Nerve Block in patients undergoing modified radical mastectomy regarding the following : 1-Post-operative opioid (morphine) consumption in the 1st 24 hours 2- Postoperative Numeric Pain Rating Scale. 3. Effect on hemodynamics: Mean arterial blood pressure and Heart rate. 4. Intraoperative fentanyl consumption. 5. Duration of analgesic effect primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE maskingDescription: The patients will be randomly assigned into two equal comparable groups using computer- generated random numbers in opaque closed envelopes, each of which will include 11 per group. Randomization will be done by statistician and each group of the patient will revealed only when the included patient is transferred to preanesthetic room. whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 22 type: ACTUAL name: Transeversus Thoracic Plane Block (TTPB) and Pectoral Nerves (PECS) Block name: Pectoral Nerves (PECS) Block measure: visual analogue scale "VAS score" measure: total morphine consumption measure: mean blood pressure measure: heart rate measure: first analgesic dose sex: FEMALE minimumAge: 20 Years maximumAge: 60 Years stdAges: ADULT facility: National cancer Insititute Cairo university city: Cairo zip: 11796 country: Egypt lat: 30.06263 lon: 31.24967 facility: National cancer Insititute city: Cairo zip: 11796 country: Egypt lat: 30.06263 lon: 31.24967 facility: Ahmed Mohamed Soliman city: Giza country: Egypt lat: 30.00808 lon: 31.21093 hasResults: False
nctId: NCT06371612 id: MersinU*GUGUCU_004 briefTitle: Effect of Ball Squeezing and Adhesive Remover Use on Pain and Fear in Children Aged 6-9 Years During the Removal of Peripheral Intravenous Cannula overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-07-30 date: 2024-11-20 date: 2024-04-17 date: 2024-04-17 name: Mersin University class: OTHER briefSummary: Pediatric nurses have a key role in reducing pain related to interventions during the hospitalisation process. In this context, according to the type of invasive intervention, the nurse determines the appropriate non-pharmacological methods for the effective management of pain, taking into account the child's individuality, developmental stage and clinical presentation. For children during the hospitalisation process, the removal of a peripheral venous line is a painful and stressful experience, as is the insertion of a peripheral venous line. Children experience acute pain during the removal of hypoallergenic adhesives used for fixation of the peripheral venous line. The practice guideline recommends the use of alcohol-free silicone-based aerosol sprays for the removal of medical adhesive/ fixation materials (NICU Brain Sensitive Care Committee, 2015).
In this study, it was aimed to examine the effect of ball squeezing (active distraction) as a distraction method and the use of alcohol-free silicone-based aerosol adhesive remover spray on pain and fear in children aged 6-9 years during peripheral intravenous cannula removal. conditions: Procedural Pain conditions: Fear of Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE maskingDescription: The children and their parents will be blinded to the groups. The principal researchers (R1, R2) will be blinded to the research hypotheses. The opaque envelopes are stored in a locked cabinet by the researcher who performed the randomization. Data entries will be performed using the codes A, B and C. Codes will be shared with the researchers after statistical analyses are conducted and the research report is written. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 96 type: ESTIMATED name: Standard Care name: Adhesive Remover Spray name: Ball Squeezing + Adhesive Remover Spray measure: Pain assesed by Wong-Baker FACES measure: Fear by Children's Fear Scale measure: Pain assesed by Wong-Baker FACES measure: Fear by Children's Fear Scale sex: ALL minimumAge: 6 Years maximumAge: 9 Years stdAges: CHILD facility: Mersin University city: Mersin state: Yenişehir zip: 33343 country: Turkey lat: 36.79526 lon: 34.61792 hasResults: False
nctId: NCT06371599 id: MersinU*GUGUCU_003 briefTitle: The Effect of Watching Cartoons and Playing Games as Distraction Method During Peripheral Intravenous Cannula Placement on Pain and Fear in Children Aged 6-9 Years overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-06-30 date: 2024-11-20 date: 2024-04-17 date: 2024-04-17 name: Mersin University class: OTHER briefSummary: Active and passive distraction methods are frequently used in the nursing management of procedural pain in children. There are no studies comparing the effects of watching cartoon (passive) and playing game (active) as distraction methods on pain and fear associated with peripheral intravenous cannula placement in children aged 6-9 years.
This study aimed to compare the effects of playing game (active distraction) and watching cartoon (passive distraction) techniques on pain and fear during peripheral intravenous cannula placement in children aged 6-9 years. conditions: Procedural Pain conditions: Fear of Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE maskingDescription: The children and their parents will be blinded to the groups. The principal researchers (R1, R2) will be blinded to the research hypotheses. The opaque envelopes are stored in a locked cabinet by the researcher who performed the randomization. Data entries will be performed using the codes A and B. Codes will be shared with the researchers after statistical analyses are conducted and the research report is written. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 64 type: ESTIMATED name: Playing game name: Watching cartoon measure: Pain assesed by Wong-Baker FACES measure: Fear by Children's Fear Scale measure: Pain assesed by Wong-Baker FACES measure: Fear by Children's Fear Scale sex: ALL minimumAge: 6 Years maximumAge: 9 Years stdAges: CHILD facility: Mersin University city: Mersin state: Yenişehir zip: 33343 country: Turkey lat: 36.79526 lon: 34.61792 hasResults: False
nctId: NCT06371586 id: NCC4537 briefTitle: Neo-Sequence 2：NCT Plus Anti-angiogenesis Therapy and Immunotherapy for LADGC overallStatus: RECRUITING date: 2024-03-01 date: 2027-03-01 date: 2027-03-01 date: 2024-04-17 date: 2024-04-17 name: Cancer Institute and Hospital, Chinese Academy of Medical Sciences class: OTHER briefSummary: The regimen of Albumin paclitaxel+SOX+BEV neoadjuvant therapy lasted for 6 cycles, during which PD-1 monoclonal antibody therapy was interspersed for 4 cycles for locally advanced diffuse gastric cancer. conditions: Gastric Cancer conditions: Diffuse Type Carcinoma studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 67 type: ESTIMATED name: Albumin paclitaxel+SOX+BEV+ PD-1 monoclonal antibody therapy measure: Pathological response rate measure: EFS measure: OS measure: R0 measure: Safety (adverse events) and surgical complications sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Cancer hospital，Chinese acadamy of medical sciences status: RECRUITING city: Beijing country: China name: Chunxia Du role: CONTACT phone: 87787121 email: retinadcx@vip.163.com lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06371573 id: MPN-USspleen briefTitle: Ultrasound Examination for Spleen Volume Evaluation in Myeloproliferative Neoplasms overallStatus: COMPLETED date: 2017-04-20 date: 2024-01-20 date: 2024-03-20 date: 2024-04-17 date: 2024-04-17 name: Federico II University class: OTHER briefSummary: Adult patients (\>18 years) with newly diagnosis of Ph negative myeloproliferative neoplasms (MPNs) according to WHO 2016 criteria, will be recruited to this study.
The patient was placed in a supine or right-sided position until complete organ visualization was achieved. Perimeter, longitudinal diameter (LD), and area, defined as the maximum measurements with splenic borders and angles clearly defined, were measured, and SV (in milliliters) was calculated automatically. For each subject, the mean value of 3 measurements repeated on the same imaging session was calculated and recorded for final analysis. Within two weeks from the US, each patient underwent an MRI of the upper abdomen to evaluate the splenic volume. MRI examinations were performed using a 3T Biograph mMR scanner (Siemens Healthcare, Erlangen, Germany) with 4-channel flex phased-array body coil. Routine clinical abdominal MRI acquisition includes coronal T2W Half-Fourier Acquisition Single-shot Turbo spin Echo imaging (HASTE), axial T1 Dual-echo FSE, axial T2 TSE Fat Sat, and an axial diffusion-weighted imaging (DWI). The DWI includes an apparent diffusion coefficient (ADC) map that was automatically generated at the time of acquisition. At last, an isotropic 2mm3 axial Volumetric Interpolated Breath-hold Examination (VIBE) sequence for SV evaluation was acquired. For the latter, attention was paid to optimize the field of view to the spleen, in order to reduce patient's apnea and possible respiratory artifacts. A radiologist with mote than 10 years of experience in abdominal MRI reporting performed measurement of the three orthogonal diameters of the spleen for each patient. Subsequently, SV was calculated using ITK-SNAP software and semi-automatic 3D segmentation approach, firstly based on a signal threshold. conditions: Myeloproliferative Neoplasm conditions: Polycythemia Vera conditions: Essential Thrombocythemia conditions: Primary Myelofibrosis conditions: Prefibrotic/Early Primary Myelofibrosis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 45 type: ACTUAL name: ULTRASOUND EXAM AND MRI SCAN measure: agreement between two different diagnostic methods sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Federico II University city: Naples zip: 80131 country: Italy lat: 40.85216 lon: 14.26811 hasResults: False
nctId: NCT06371560 id: KAP-ABR-Perio briefTitle: Antibiotics, Antibiotic Resistance, and Prescribing Practices Among Periodontists: Cross Sectional KAP Study overallStatus: NOT_YET_RECRUITING date: 2024-04-25 date: 2024-09-30 date: 2024-10-30 date: 2024-04-17 date: 2024-04-23 name: Cairo University class: OTHER briefSummary: Antibiotic resistance is a global health threats that require attention from all healthcare providers. In Periodontology, antibiotic is prescribed in many clinical situations. The aim of this study is to assess the followings among Periodontists (1) The knowledge, attitude, and practices (KAP) towards antibiotics and antibiotic resistance; (2) The prescribing practices of antibiotics in periodontal therapy; (3) The correlation between personal perception of antibiotics uses and the professional prescription patterns; and (4) The differences in antibiotics prescription in relation to the years of experience and the academic background. conditions: Antibiotic Resistance conditions: Antibiotic Use conditions: Periodontitis studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 400 type: ESTIMATED name: Questionnaire measure: KAP measure: The prescribing practices of antibiotics in periodontal therapy measure: The correlation between personal perception of antibiotics uses and the professional prescription patterns measure: The differences in antibiotics prescription in relation to the years of experience and the academic background. sex: ALL minimumAge: 25 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06371547 id: BEUFTR-3 briefTitle: Efficiency of Different Gastrocnemius Stretching Exercises overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2024-10-15 date: 2024-12-15 date: 2024-04-17 date: 2024-04-17 name: Bitlis Eren University class: OTHER briefSummary: The primary aim of this study is to investigate the effects of different types and durations of gastrocnemius stretching on the viscoelastic properties of the gastrocnemius muscle, Achilles tendon, and plantar fascia.In addition, pain threshold of the gastrocnemius muscle and plantar fascia, as well as on hamstring tightness will be measured. conditions: Muscle Tightness studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Interventions and assessment will be performed by separate researchers. whoMasked: OUTCOMES_ASSESSOR count: 48 type: ESTIMATED name: Stretching Exercise measure: Measurement of the Viscoelastic Properties measure: Ankle-foot Dorsiflexion Index measure: Measurement of the Mechanosensitivity measure: Assessment of Hamstring Tightness measure: Dominant Leg Determination measure: Navicular Drop Test measure: Self-reported Effects of Stretching Exercises measure: The Satisfaction Level with the Stretching measure: Compliance with Stretching Exercise Program sex: ALL minimumAge: 18 Years maximumAge: 25 Years stdAges: ADULT facility: Bitlis Eren University city: Bitlis state: Merkez zip: 13000 country: Turkey lat: 38.40115 lon: 42.10784 hasResults: False
nctId: NCT06371534 id: QL2109-101 briefTitle: A Study Comparing Pharmacokinetic and Safety of QL2109 and DARZALEX FASPRO® in Healthy Adults overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-04 date: 2025-04 date: 2024-04-17 date: 2024-04-17 name: Qilu Pharmaceutical Co., Ltd. class: INDUSTRY briefSummary: The goal of this clinical trial is to compare the pharmacokinetic and safety similarity of QL2109 with DARZALEX FASPRO® in healthy male volunteers.
Participants will receive a single injection of QL2109/ DARZALEX FASPRO® Researchers will compare pharmacokinetic, safety, and immunogenic similarities between the two groups. conditions: Tumor studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 228 type: ESTIMATED name: QL2109 name: DARZALEX FASPRO® measure: AUC0-∞ measure: Cmax sex: MALE minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: The First Affiliated Hospital of Zhejiang University School of Medicine city: Hangzhou state: Zhejiang zip: 310006 country: China name: qingwei zhao, Professor role: CONTACT email: qwzhao@zju.edu.cn name: qingwei zhao, Professor role: PRINCIPAL_INVESTIGATOR name: xingjiang hu, Professor role: PRINCIPAL_INVESTIGATOR lat: 30.29365 lon: 120.16142 facility: The First Affiliated Hospital of Zhejiang University School of Medicine city: Hangzhou state: Zhejiang zip: 310006 country: China name: qingwei ZHAO, Professor role: CONTACT email: qwzhao@zju.edu.cn name: xingjiang HU, Professor role: CONTACT email: hxj319@163.com name: qingwei ZHAO, Professor role: PRINCIPAL_INVESTIGATOR name: xingjiang HU, Professor role: PRINCIPAL_INVESTIGATOR lat: 30.29365 lon: 120.16142 hasResults: False
nctId: NCT06371521 id: 4933 briefTitle: Ergogenic Effects of Sportlegs overallStatus: RECRUITING date: 2024-01-24 date: 2024-06-01 date: 2024-06-01 date: 2024-04-17 date: 2024-04-17 name: Christopher Bell class: OTHER briefSummary: Sportlegs is a commercially available dietary/sports supplement. It is manufactured by a local, Colorado-based company: Sport Specifics Inc. Although Sportlegs has been on the market for approximately 20-years, very little empirical research has been completed to determine if Sportlegs improves exercise performance. Sport Specifics Inc. has commissioned Colorado State University to investigate the ergogenic effects of Sportlegs. conditions: Performance Enhancing Product Use studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Randomized, Placebo-Controlled, Double Blind Crossover Intervention primaryPurpose: BASIC_SCIENCE masking: TRIPLE maskingDescription: Investigators and Participants are both blinded to whether the participants will be consuming Sportlegs or Placebo during a given study visit. whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 15 type: ESTIMATED name: Sportlegs name: Placebo measure: Maximal Oxygen Uptake measure: Lactate Threshold measure: Rating of Perceived Exertion (RPE) measure: Maximal sustained mean power sex: ALL minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT facility: Colorado State University status: RECRUITING city: Fort Collins state: Colorado zip: 80523 country: United States name: Christopher Bell, Ph.D. role: CONTACT phone: 970-491-7522 email: christopher.bell@colostate.edu name: Taylor R Ewell, MS role: CONTACT phone: 7197611417 email: taylor.ewell@colostate.edu lat: 40.58526 lon: -105.08442 hasResults: False
nctId: NCT06371508 id: 14042024 briefTitle: Breast Cancer and Breast Self-examination Education overallStatus: RECRUITING date: 2024-02-01 date: 2024-05-15 date: 2024-06-15 date: 2024-04-17 date: 2024-04-17 name: Sakarya University class: OTHER briefSummary: According to a news published by the World Health Organization (WHO); More than 2.3 million cases of breast cancer occur each year, making it the most common cancer among adults. In 95% of all countries, breast cancer is the first or second cause of female cancer death. In 2020, 2.3 million women worldwide were diagnosed with breast cancer and 685,000 deaths occurred (WHO, 2023; https://www.who.int/news/item/03-02-2023-who-launches-new-roadmap- on-breast-cancer). In our country, breast cancer ranks first among the most common cancer types in women, and the number of breast cancer cases in women in 2020 was recorded as 74 638 (IARC, 2023). As a result of this situation, WHO (2023) published the Global Breast Cancer Initiative Framework to save 2.5 million lives from breast cancer by 2040. This published framework includes health promotion for early detection, timely diagnosis and comprehensive management of breast cancer.
One of the most effective ways to reduce breast cancer mortality and morbidity rate is early diagnosis. It is important to determine early diagnosis and signs and symptoms of cancer before they appear. Early diagnosis of breast cancer is possible with breast self-examination (BSE), clinical breast examination and mammography (Kayar, 2019). Breast self-examination is an important examination method in terms of detecting changes in breast tissue and preventing subsequent complications (Abo Al-Shiekh et al., 2021). It is also an easy-to-apply, cheap and non-invasive method. In our country, it is recommended that women regularly perform breast self-examination every month after the age of 20, women between the ages of 20 and 40 should have a clinical breast examination every two years, and women between the ages of 40 and 69 should have a clinical breast examination every year and have a mammogram every two years (Ministry of Health, 2019). .
There are studies showing that fear of breast cancer has a positive and negative impact on early diagnosis behaviors (Champion et al., 2004; Yavan et al., 2010). Champion et al. (2004) stated that women with moderate breast cancer fear had a high rate of early detection behavior, whereas low and high fear levels had a negative effect on behavior. In the study conducted by Yavan et al. (2010) on 188 women, 2% of the women. They found that 3 of them had regular BSE and 78.7% of them had never had a mammography. In addition, 85% of the women included in the study stated that they had a fear of breast cancer due to a family history of breast cancer, being diagnosed with breast cancer, and the presence of risk factors. Study results show that fear of breast cancer affects screening results. Therefore, our aim in the study is; To determine the effect of breast cancer and BSE training given to women on breast cancer fear and BSE skills. conditions: Breast Cancer conditions: Breast Self-Examination studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 96 type: ESTIMATED name: Education based on breast cancer and breast examination measure: Champion Breast Cancer Fear Scale Change measure: Breast Self Examination Checklist Success Score sex: FEMALE minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Kocadere Sağlık Evi status: RECRUITING city: Yalova country: Turkey name: Muge Saglık, Msc. role: CONTACT phone: +905343817563 email: mge.saglk@gmail.com lat: 40.65501 lon: 29.27693 hasResults: False
nctId: NCT06371495 id: statins in ischemic stroke briefTitle: Statins Role in Acute Ischemic Stroke acronym: observation overallStatus: NOT_YET_RECRUITING date: 2024-08-13 date: 2025-02-28 date: 2025-08-30 date: 2024-04-17 date: 2024-04-17 name: Assiut University class: OTHER briefSummary: Strokes is amajor cause of death and disabilities in different countried conditions: Stroke, Acute studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 105 type: ESTIMATED name: rosuvastatin measure: Carotid duplex will be done at the onset and after 1 month and 3 months of the onset. sex: ALL minimumAge: 20 Years maximumAge: 99 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False