hackint0sh/New-Dataset huggingface dataset:
Parents who choose to be in this study will complete a survey to help researchers figure out if the parent is eligible for the larger study. If a parent is eligible for the larger study and chooses to participate, if so, the participants will be randomly assigned to either receive the I-PCIT intervention now or to be on a waitlist and begin I-PCIT in 5-6 months. The whole study consists of completing I-PCIT sessions with a clinician and completing 3-4 follow-up surveys after the initial screener survey. conditions: Pediatric Cancer conditions: Oncology conditions: Disruptive Behavior studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: This is a pilot feasibility trial. We are using a 2:1 (intervention: waitlist control) randomized controlled design. primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 300 type: ESTIMATED name: Internet-Based Parent-Child Interaction Therapy measure: I-PCIT Feasibility as assessed by intervention completion measure: I-PCIT Acceptability as assessed by the Treatment Evaluation Inventory Short form sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Johns Hopkins All Children's Hospital status: RECRUITING city: Saint Petersburg state: Florida zip: 33701 country: United States name: Melissa Faith, Ph.D. role: CONTACT phone: 727-295-8477 email: mfaith1@jhmi.edu lat: 27.77086 lon: -82.67927 hasResults: False
nctId: NCT06346769 id: SelcukB briefTitle: Composite Restorations Performed by Placing Polyethylene Fiber overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-01 date: 2024-10-15 date: 2025-04-15 date: 2024-04-04 date: 2024-04-04 name: Selcuk University class: OTHER briefSummary: This study aimed to evaluate the 12-month clinical performance of direct composite restorations by placing polyethylene fibers in different directions in endodontically treated posterior teeth. In this clinical study, Clearfil SE Bond (Kuraray/Japan) adhesive system, G-aenial Universal Injectable (GC/Tokyo, Japan), G-aenial A'chord (GC/Tokyo, Japan) composites, and polyethylene fiber (Ribbond, USA) were used. In the restoration of the teeth included in the study, polyethylene fiber was placed in different directions according to the amount of remaining tooth tissue and cavity preparation. The restorations were divided into three groups according to the direction of fiber placement ('O' shape, mesiodistal I shape, buccolingual I shape) (n=12). Restorations were evaluated according to modified USPHS criteria in 1st week and 6th months from the placement date. The Chi-square test was used for statistical analysis of the difference between the groups, and the Cochran Q test was used for the significance of the difference between time-dependent changes within each group (p\<0.05). conditions: Endodontically Treated Teeth studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 68 type: ACTUAL name: Polyethylene Fiber measure: Retention measure: Color match measure: Marginal Discoloration measure: Marginal adaptation measure: Secondary caries measure: Surface texture measure: Anatomical form sex: ALL minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Selcuk University, Faculty of Dentistry, Restorative Dentistry Department city: Konya country: Turkey lat: 37.87135 lon: 32.48464 facility: Selcuk University, Faculty of Dentistry city: Konya country: Turkey lat: 37.87135 lon: 32.48464 hasResults: False
nctId: NCT06346756 id: SelcukA briefTitle: Clinical Evaluation of Class II Restorations overallStatus: COMPLETED date: 2023-01-01 date: 2023-07-01 date: 2023-07-15 date: 2024-04-04 date: 2024-04-04 name: Selcuk University class: OTHER briefSummary: This study aims to evaluate the one-year clinical performance of Class II restorations made with high-filling injectable and condensable universal composite resins.
The study included 62 patients and 147 restorations. It used G-aenial Universal Injectable (GCI), G-aenial A'CHORD (GCA), Tetric Prime (TP), Filtek Ultimate (FU) composites, and the Clearfil SE Bond adhesive system. GCI only in premolar teeth; GCA, TP, and FU have been used to restore premolar and molar teeth. Restorations were evaluated and scored according to modified USPHS criteria at seven days, six months, and one year. Chi-square and Cochran Q tests were used for statistical analysis (p\<0.05). conditions: Dental Caries conditions: Dental Caries Class II studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 62 type: ACTUAL name: Treatment of dental caries. measure: Retention measure: color match measure: marginal adaptation measure: marginal discoloration measure: surface texture measure: anatomical form measure: secondary caries measure: postoperative sensitivity sex: ALL minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Selcuk University, Faculty of Dentistry city: Konya country: Turkey lat: 37.87135 lon: 32.48464 hasResults: False
nctId: NCT06346743 id: IRB/2023/1119/SIMS briefTitle: Comparison of Effects of Fenofibrate Adjuvant Therapy Versus Conventional Phototherapy in Neonatal Jaundice. overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-07 date: 2024-08 date: 2024-04-04 date: 2024-04-04 name: Muhammad Zark class: OTHER_GOV briefSummary: Neonatal jaundice has significant importance in neonatal morbidity and mortality world-wide. Though phototherapy has a relentless use in neonatal jaundice, its cumbersome side effects and the physical separation of baby from the mother eventually result as increase in days of hospitalization adding to the mental anguish of the parents. This study is conducted to observe the reduction of serum bilirubin level in neonates treated with Fenofibrate as an adjuvant to phototherapy in treatment of exaggerated physiological hyperbilirubinemia. After informed consent, single dose of Fenofibrate will be given to the group A (intervention group) and Group B (non-intervention) will only be given phototherapy. Then every 24-hourly sample for serum bilirubin will be sent for lab analysis, for 3 days. A randomized control trial is conducted and later on, the data will be analyzed in the SPSS 26. Quantitative variables like age will be presented as mean ± SD. Qualitative variables like gender will be presented as percentage and frequency. Comparison of two groups intervention group and non-intervention group, apply independent sample t-test. P value \< 0.05 will be taken as significant. Limitation of the proposed study includes limited sample size, study population limited to only one hospital and no follow-up in plan. If the role of Fenofibrate is established in the management of exaggerated physiological hyperbilirubinemia in newborns, it will be beneficial to minimize the risk of the complications, rapid regression of hyperbilirubinemia \& shortening the length of hospital stay. conditions: Physiological Neonatal Jaundice conditions: Physiological Hyperbilirubinaemia studyType: INTERVENTIONAL phases: PHASE2 phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: To compare the effects of Fenofibrate adjuvant to phototherapy with conventional phototherapy for exaggerated neonatal hyperbilirubinemia in the form of bilirubin reduction, duration of phototherapy, hospital stay \& observation of side-effects.
After informed consent, single dose of Fenofibrate will be given to the group A (intervention group) and Group B (non-intervention) will only be given phototherapy. Then every 24-hourly sample for serum bilirubin will be sent for lab analysis, for 3 days. A randomized control trial is conducted. primaryPurpose: TREATMENT masking: NONE count: 156 type: ESTIMATED name: Fenofibrate name: Phototherapy measure: number of days needed for serum bilirubin to decrease below phototherapy range measure: Hospital length of Stay sex: ALL minimumAge: 24 Hours maximumAge: 14 Days stdAges: CHILD facility: Services Institute of Medical Sciences city: Lahore state: Punjab zip: 54000 country: Pakistan name: Noman Abdullah role: CONTACT phone: +923124100143 email: info@sims.edu.pk name: Muhammad Zark, MBBS role: PRINCIPAL_INVESTIGATOR lat: 31.558 lon: 74.35071 hasResults: False
nctId: NCT06346730 id: 142-18 briefTitle: The Effect of Virtual Reality Application on Anxiety and Patient Satisfaction During Intrauterine Insemination (IUI) acronym: (IUI) overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2024-08-30 date: 2024-09-30 date: 2024-04-04 date: 2024-04-09 name: Suleyman Demirel University class: OTHER briefSummary: This study will conduct as a randomized pretest-posttest study to examine the effect of virtual reality glasses (VRG) application during the IUI procedure on anxiety and patient satisfaction. The population of the research will consist of women who were treated with assisted reproductive techniques and underwent IUI at the infertility polyclinic of Ministry of Health Adana City Training and Research Hospital between May and December 2024 and who meet the research criteria. The research sample was calculated as a total of 90 people (at least 45 people in each group) using the power program. Data; Personal Information Form, Visual Assessment Scale (VAS), State Trait Anxiety Inventory (STAI) and Patient's Perception of Nursing Care Scale will be collected from women who agree to participate in the research. Virtual reality glasses will be applied to the intervention group. conditions: Virtual Reality conditions: Anxiety conditions: Patient Satisfaction conditions: Intrauterine Insemination (IUI) studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The sample will divide into intervention and control groups primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 90 type: ESTIMATED name: Virtual reality glasses to intervention group measure: State Trait Anxiety Inventory (STAI) measure: Patient's Perception of Nursing Care Scale sex: FEMALE minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT hasResults: False
nctId: NCT06346717 id: SINOPU-elif 2 briefTitle: Mobile Application Based Care for Total Knee Prosthesis Patients acronym: KneeMobilApp overallStatus: RECRUITING date: 2024-03-27 date: 2025-03-30 date: 2025-03-30 date: 2024-04-04 date: 2024-04-04 name: Sinop University class: OTHER briefSummary: Total knee prosthesis (TKP); It is a surgical treatment used in the management of functional limitations and severe pain occurring on the degenerated joint surface as a result of rheumatoid arthritis, osteoarthritis, posttraumatic arthritis and other nonspecific arthritis. Nursing care is of great importance in the success of TKP surgery. Reducing pain, preventing complications, increasing self-care ability, and improving the quality of life by improving postoperative knee functions are the main goals of postoperative nursing care. In order to achieve these goals, patients and their relatives need to receive training on home care in the post-operative period before discharge. With the increasing use of mobile technologies in daily life and the increasing adoption of e-health, the opportunity for people to improve their self-management skills through e-health is increasing. Mobile Health (m-Health) provides convenience in many areas such as educating the public, warning about potential diseases and disease risks, and communicating with messages, notifications and video when necessary. It also affects the way nursing services are delivered and provides great benefits in the delivery of nursing services. For all these reasons, it was aimed to examine the effect of mobile application-supported care given to patients with total knee prosthesis on functional status and self-care ability. conditions: Knee Prosthesis conditions: Mobile Application studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: PARTICIPANT count: 60 type: ESTIMATED name: "Knee Prosthesis-M" mobile application service measure: Knee Injury and Osteoarthritis Outcome Score = KOOS measure: Exercise of Self-Care Agency=ESCA sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Elif ALTINKAYNAK SARAL status: RECRUITING city: Merkez state: Osmaniye Köyü zip: 5700 country: Turkey name: ELİF ALTINKAYNAK SARAL, PhD role: CONTACT phone: 05436071986 email: ealtinkynk@hotmail.com name: Sonay GÖKTAŞ, PhD role: CONTACT phone: 05324567776 email: sonay.goktas@sbu.edu.tr hasResults: False
nctId: NCT06346704 id: PR5030-66 briefTitle: Prospective Longitudinal Monocentric Study to Evaluate the Syde® Digital Endpoint in Patients With Multiple Sclerosis acronym: NHS-MS-EGYPT overallStatus: NOT_YET_RECRUITING date: 2024-04-25 date: 2026-11-30 date: 2026-11-30 date: 2024-04-04 date: 2024-04-04 name: SYSNAV class: INDUSTRY briefSummary: The study aims to assess the validity of real-world activity monitoring by the Syde® wearable device in subjects with multiple slclerosis. The Syde® collected data will be compared to on-site conventional clinical endpoints for MS pathology (EDSS, FSS and T25FWT). Subjects with multiple sclerosis will be assessed every 6 months for 2 years. conditions: Multiple Sclerosis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED name: Digital HealthTechnology measure: Longitudinal change of 95th centile of stride velocity measure: Correlation of the Syde® variables with the clinical assessments EDSS, FSS and T25FWT sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06346691 id: MTU-EC-IM-0-235/66 briefTitle: Bronchodilator Effect of Oral Doxofylline and Procaterol in Chronic Obstructive Pulmonary Disease overallStatus: NOT_YET_RECRUITING date: 2024-04-16 date: 2024-09-30 date: 2024-12-31 date: 2024-04-04 date: 2024-04-05 name: Thammasat University class: OTHER briefSummary: The goal of this clinical trial is to determine if doxofylline and procaterol are effective in treating patients with stable chronic obstructive pulmonary disease (COPD). It will also assess the safety of both drugs.
* What medical problems do participants experience when taking doxofylline and procaterol?" conditions: COPD studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Crossover randomized controlled trial primaryPurpose: TREATMENT masking: NONE count: 20 type: ESTIMATED name: Doxofylline name: Procaterol measure: Forced expiratory volume in 1 second (FEV1) measure: Forced vital capacity (FVC) measure: Forced expiratory flow at 25-75% of FVC (FEF25-75) measure: modified Medical Research Council (mMRC) score measure: COPD Assessment Test (CAT) sex: ALL minimumAge: 40 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06346678 id: MTU-EC-IM-0-016/67 briefTitle: Accuracy of Accuhaler Tester, Ellipta Tester and Turbutester in Patients With Chronic Obstructive Pulmonary Disease overallStatus: NOT_YET_RECRUITING date: 2024-04-16 date: 2024-08-31 date: 2024-10-31 date: 2024-04-04 date: 2024-04-04 name: Thammasat University class: OTHER briefSummary: The goal of this observational study is to investigate the accuracy of Accuhaler tester, Ellipta tester and Turbutester in patients with chronic obstructive pulmonary disease (COPD). The main question it aims to answer is:
• Do Accuhaler tester, Ellipta tester, and Turbutester demonstrate comparable accuracy to the In-check DIAL for assessing inspiratory inhalation force in COPD patients? conditions: Chronic Obstructive Pulmonary Disease studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 80 type: ESTIMATED name: Accuhaler tester measure: Accuracy of Accuhaler tester measure: Accuracy of Ellipta tester measure: Accuracy of Turbutester measure: Prevalence of suboptimal peak inspiratory flow rate measure: Prevalence of insufficient peak inspiratory flow rate sex: ALL minimumAge: 40 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06346665 id: DZIF Tx-Cohort briefTitle: The Transplant Cohort of the German Center for Infection Research overallStatus: RECRUITING date: 2016-01 date: 2025-12 date: 2030-12 date: 2024-04-04 date: 2024-04-23 name: Technical University of Munich class: OTHER name: Hannover Medical School name: University Hospital Heidelberg name: Universität Tübingen name: Klinikum der Universität München name: Max von Pettenkofer-Institut München name: Nierenzentrum Heidelberg name: Helmholtz Centre for Infection Research briefSummary: Medical data and biological samples obtained from transplant patients are collected and managed across Germany with the help of the DZIF Transplant Cohort. The data and samples form the basis of scientific studies which investigate the connections between numerous factors influencing an organ's susceptibility to infection and organ function. conditions: Infections conditions: Transplant Complication conditions: Transplant Failure conditions: Immunosuppression studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 3000 type: ESTIMATED measure: Realisation of studies that focus on the the medical needs of transplant patients, particularly with regard to their susceptibility to infection sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Technische Universität München status: RECRUITING city: München country: Germany name: Daniela Schindle, Dr. role: CONTACT lat: 48.13743 lon: 11.57549 hasResults: False
nctId: NCT06346652 id: REC-UOL-216-03-2024 briefTitle: Effects of Core Strengthening and PNF Pattern on Static Balance and Plantar Pressure in Chronic Stroke Patients overallStatus: RECRUITING date: 2024-03-10 date: 2024-04-22 date: 2024-04-30 date: 2024-04-04 date: 2024-04-04 name: University of Lahore class: OTHER briefSummary: Stroke is a neurological disease characterized by neurological deficits caused by insufficiency of blood supply to brain. Disruption of blood supply to brain can be due to blockage of blood supply (ischemic) or leakage of blood in brain due to rupture of blood vessel (hemorrhagic). 90.5% of global occurrence of stroke was subjected to modifiable risk factors according to Global Burden of Disease study.
This study aims to compare the effects of core strengthening and proprioceptive neuromuscular facilitation on static standing balance and plantar pressure in chronic stroke patients. conditions: Chronic Stroke studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 73 type: ESTIMATED name: Routine Physical Therapy name: Routine Physical Therapy+ PNF and Core Stregthening measure: Static Standing Balance measure: Plantar Pressure sex: ALL minimumAge: 45 Years maximumAge: 60 Years stdAges: ADULT facility: The University of Lahore Teaching Hospital status: RECRUITING city: Lahore zip: 54000 country: Pakistan name: Safa Saleem, MSPTN role: CONTACT phone: 03354028864 email: safah.saleem@gmail.com name: Sameed Liaqat, MPhil role: CONTACT phone: 03249004200 email: samiliaqat3@gmail.com lat: 31.558 lon: 74.35071 hasResults: False
nctId: NCT06346626 id: 2WIN-S2024 briefTitle: To Evaluate the Consistency and Repeatability of Portable Automatic Optometry 2-WINS for Cycloplegic Optometry in Adolescents and Children overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-06-01 date: 2024-06-01 date: 2024-04-04 date: 2024-04-04 name: He Eye Hospital class: OTHER briefSummary: Myopia, also known as short-sightedness or near-sightedness, is a prevalent condition that typically emerges during childhood and early adulthood. It occurs when the eye elongates excessively, causing images of distant objects to focus in front of the retina, leading to blurred distance vision. The number of people with myopia is increasing every year, reaching half of the world's population by 2050. The global potential productivity loss due to uncorrected refractive errors was $244 billion in 2015. Due to the strong association between high myopia and pathological changes in the choroid, retina, and sclera, leading to irreversible vision loss, and the fact that correcting the refractive error does not halt the progression of pathology, the prevention of myopia, especially high myopia, has emerged as a crucial international public health concern. In ocular examinations of children under noncycloplegic conditions, the influence of accommodation cannot be disregarded.
Cycloplegic refraction is widely regarded as the gold standard in epidemiological assessment of refractive errors in pediatric populations. Moreover, due to children's decreased cooperation and unreliable responses, subjective refraction tests are less valued, and objective tests under cycloplegia are preferred. The portable vision screener 2WIN-S is a binocular tool that detects various ocular abnormalities and measures the refraction of both eyes. Along with measuring phorias/tropias in prismatic diopters and objective refraction in the range of -15D to +15D, 2WIN-S also captures additional features.
This study employed the cycloplegic condition to measurements using 2WIN-S, ARK-1 and subjective testing, we wanted to test the reliability and accuracy of 2WIN-S. conditions: Optometry studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 150 type: ESTIMATED measure: The optometric result (2WIN-S) measure: The optometric result(ARK-1) measure: The optometric result(subjective refraction) measure: The optometric result sex: ALL minimumAge: 3 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT hasResults: False
nctId: NCT06346613 id: B2024-076R briefTitle: Prevalence and Affecting Factors of Sleep and Circadian Rhythm Disorders in ICU overallStatus: RECRUITING date: 2024-03-07 date: 2025-01-31 date: 2025-12-31 date: 2024-04-04 date: 2024-04-04 name: Shanghai Zhongshan Hospital class: OTHER briefSummary: Most ICU patients experience sleep and circadian disruption (SCD), which causes a profound negative impact on patients, such as prolonged mechanical ventilation, glucose intolerance, and the occurrence of delirium. In order to better promote the alignment of circadian rhythm in ICU patients, this project will explore the prevalence of SCD and a series of influencing factors contributing to SCD in ICU patients, to help construct targeted intervention programs in the future. conditions: Sleep Deprivation conditions: Circadian Rhythm Disorders conditions: Critical Illness studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 56 type: ESTIMATED measure: Rhythmicity of melatonin levels. measure: Overnight sleep duration measure: Wake after sleep onset(WASO) measure: Overnight Rapid Eye Movement (REM) proportion measure: Overnight non-rapid eye movement stage 1 (NREM1) proportion measure: Overnight non-rapid eye movement stage 2 (NREM2) proportion measure: Overnight non-rapid eye movement stage 3 (NREM3) proportion measure: Sleep period time ratio (sleep continuity) measure: Subject sleep quality measure: Activity counts sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: 180 Fenglin Road status: RECRUITING city: Shanghai zip: 20032 country: China name: Shining Cai, MSc role: CONTACT phone: 86-021-64041990 phoneExt: 2724 email: cai.shining@zs-hospital.sh.cn name: Yuxia Zhang, PhD role: PRINCIPAL_INVESTIGATOR lat: 31.22222 lon: 121.45806 hasResults: False