The study will last about 33 weeks for each participant, including screening (1 week), Lead-in period (4 weeks), treatment period (26 weeks) and follow up period (2 weeks). conditions: Diabetes Mellitus, Type 2 studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 112 type: ESTIMATED name: Insulin Lispro-aabc name: Insulin Glargine measure: Percentage of Participants with at least 1 Episode of Hypoglycemia measure: Percentage of Participants with Severe Hypoglycemic Events measure: Percentage of Participants with Nocturnal Hypoglycemia Events measure: Percentage of Participants with Nocturnal and All Documented Hypoglycemic Events measure: Change from Baseline to Week 26 in Body Weight measure: Change from Baseline to Week 26 in Insulin Treatment Satisfaction Questionnaire (ITSQ) Score measure: Change from Baseline to Week 26 in Hemoglobin A1c (HbA1c) measure: Percentage of Participants Achieving HbA1c Less Than (<) 7% measure: Change from Baseline to Week 26 in 1- and 2-hour Postprandial Glucose (PPG) Values measure: Change from Baseline to Week 26 in Bolus Insulin Dose, Basal Insulin Dose, and Basal: Bolus Ratio measure: Change from Baseline to Week 26 in 9-Point Self-Monitored Blood Glucose (SMBG) Values sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: King George Hospital, Visakhapatnam city: Vizag state: Andhra Pradesh zip: 530002 country: India name: Bongi Vivekanand role: PRINCIPAL_INVESTIGATOR lat: 17.68009 lon: 83.20161 facility: Diabetes Research Centre city: Royapuram state: Chennai zip: 600013 country: India name: VIJAY VISHWANATHAN role: PRINCIPAL_INVESTIGATOR lat: 13.11405 lon: 80.29474 facility: Vijyaratna Dibetes Diagnosis Treatment Centre city: Ahmedabad state: Gujarat zip: 380007 country: India name: Sanjeev Phatak role: PRINCIPAL_INVESTIGATOR lat: 23.02579 lon: 72.58727 facility: Center for Diabetes and Endocrine Care city: Bengaluru state: Karnataka zip: 560043 country: India name: K M Prasanna Kumar role: PRINCIPAL_INVESTIGATOR lat: 12.97194 lon: 77.59369 facility: Chellaram Diabetes Institute city: Pune state: Maharashtra zip: 411021 country: India name: Unnikrishnan Gopalkrishnan role: PRINCIPAL_INVESTIGATOR lat: 18.51957 lon: 73.85535 facility: Sahyadri Super Speciality Hospital city: Pune state: Maharashtra country: India name: Uday Phadke role: PRINCIPAL_INVESTIGATOR lat: 18.51957 lon: 73.85535 facility: S. P. Medical College & A G Hospital city: Bikaner state: Rajasthan zip: 334003 country: India name: Bal Kishan Gupta role: PRINCIPAL_INVESTIGATOR lat: 28.01762 lon: 73.31495 facility: Rajasthan University of Health Sciences city: Jaipur state: Rajasthan zip: 302033 country: India name: Sudhir Bhandari role: PRINCIPAL_INVESTIGATOR lat: 26.91962 lon: 75.78781 facility: Kovai Diabetes Speciality Center and Hospital city: Coimbatore state: Tamil Nadu zip: 641009 country: India name: Ramanathan Balamurugan role: PRINCIPAL_INVESTIGATOR lat: 11.00555 lon: 76.96612 facility: Osmania Medical College & Hospital city: Hyderabad state: Telangana zip: 500012 country: India name: Rakesh Sahay role: PRINCIPAL_INVESTIGATOR lat: 17.38405 lon: 78.45636 facility: Brij Medical Center Pvt. Ltd. city: Kanpur state: Uttar Pradesh zip: 208020 country: India name: brij mohan role: PRINCIPAL_INVESTIGATOR lat: 26.46523 lon: 80.34975 facility: Medical College & Hospital, Kolkata city: Kolkata state: West Bengal zip: 700073 country: India name: Animesh Maiti role: PRINCIPAL_INVESTIGATOR lat: 22.56263 lon: 88.36304 hasResults: False