hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06277947 id: SYSKY-2024-096-01 briefTitle: Administration of Hyperthermic Intraperitoneal Chemotherapy in the General Ward acronym: GARD-HIPEC overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2024-12 date: 2025-05 date: 2024-02-26 date: 2024-02-26 name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University class: OTHER name: Shenshan Medical Center, Memorial Hospital of Sun Yat-sen University briefSummary: Ovarian cancer is the most lethal gynecologic malignancy. The majority of patients get diagnosed with advanced disease with peritoneal dissemination.It has been demonstrated that the addition of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) to interval debulking surgery can improve the prognosis. The National Comprehensive Cancer Network (NCCN) treatment guideline has recommended HIPEC as a first-line treatment for patients with advanced ovarian cancer. However, the guideline recommended the "Dutch model" of HIPEC, which is limited for routinely being performed in China. So we propose a HIPEC treatment modality, the bedside closed HIPEC in the general ward (C-HIPEC), which is suitable for the clinical characteristics of China. The aim of this study was to evaluate the safety of this model as a way to lay the foundation for subsequent efficacy evaluation and clinical promotion. conditions: Epithelial Ovarian Cancer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Patients would receive C-HIPEC in the general ward after interval debulking surgery in 24 hours. primaryPurpose: TREATMENT masking: NONE count: 92 type: ESTIMATED name: China Hyperthermic Intraperitoneal Chemotherapy(C-HIPEC) measure: The incidence of adverse events of grade 3-5 measure: Time to progress (TTP) measure: The Time to the First Subsequent Therapy，TTFST measure: Quality of life, QLQ-C30 sex: FEMALE minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University city: Guangzhou country: China lat: 23.11667 lon: 113.25 hasResults: False
nctId: NCT06277921 id: 110-2 briefTitle: Morbidity and Mortality After Esophageal and Esophagogastric Junction Cancer Surgery acronym: ESOSTAT overallStatus: NOT_YET_RECRUITING date: 2024-03-18 date: 2024-09-18 date: 2024-12-31 date: 2024-02-26 date: 2024-02-26 name: P. Herzen Moscow Oncology Research Institute class: OTHER_GOV name: National Medical Research Radiological Centre of the Ministry of Health of Russia briefSummary: Esophageal and esophagogastric junction cancer is still one of the main health care issue and esophagectomy with lymph node dissection is the only chance to be cure.
However, esophagectomy for esophageal cancer is a complex procedure which carries high risk of morbidity rate of 24% and a mortality rate of 2% to 5.6%, respectively There is a need to study the differences of 90-day postoperative morbidity and mortality in different clinics and centers of the Russian Federation. conditions: Esophageal Cancer conditions: Oesophageal Cancer conditions: Siewert Type I Adenocarcinoma of Esophagogastric Junction conditions: Siewert Type III Adenocarcinoma of Esophagogastric Junction studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 400 type: ESTIMATED name: Elective Surgery for gastric cancer measure: the type of complications and the incidence of it sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: A.S. Loginov Moscow Clinical Scientific Center city: Moscow country: Russian Federation lat: 55.75222 lon: 37.61556 facility: I.M. Sechenov First Moscow State Medical University city: Moscow country: Russian Federation lat: 55.75222 lon: 37.61556 facility: P.Herzen Moscow Oncological Research Institute city: Moscow country: Russian Federation name: Andrey Ryabov role: CONTACT name: Nuriddin Abdulkhakimov role: CONTACT lat: 55.75222 lon: 37.61556 facility: Petrovsky National Research Centre of Surgery city: Moscow country: Russian Federation lat: 55.75222 lon: 37.61556 facility: Vishnevsky National Medical Research Center of Surgery city: Moscow country: Russian Federation lat: 55.75222 lon: 37.61556 facility: Nizhny Novgorod Regional Clinical Oncological Dispensary city: Nizhny Novgorod country: Russian Federation lat: 56.32867 lon: 44.00205 facility: A.Tsyb Medical Radiological Research Centre city: Obninsk country: Russian Federation lat: 55.09681 lon: 36.61006 facility: National Medical Research Centre for Oncology city: Rostov-on-Don country: Russian Federation lat: 47.23135 lon: 39.72328 facility: Petrov National Medical Research Center of Oncology city: Saint Petersburg country: Russian Federation lat: 59.93863 lon: 30.31413 hasResults: False
nctId: NCT06277908 id: 110-1 briefTitle: Postoperative Morbidity and Mortality After Gastric Cancer Surgery acronym: GASTROSTAT overallStatus: NOT_YET_RECRUITING date: 2024-03-18 date: 2024-09-18 date: 2024-12-31 date: 2024-02-26 date: 2024-02-26 name: P. Herzen Moscow Oncology Research Institute class: OTHER_GOV name: National Medical Research Radiological Centre of the Ministry of Health of Russia briefSummary: Gastric cancer is still one of the main health care issue and gastrectomy with lymph node dissection is the only chance to be cure. Trials show that the postoperative course differs significantly between eastern and western centers, as well as between clinics within Russian Federation. Postoperative 30-day postoperative mortality after gastric cancer surgery ranges from 1% to 5%, and postoperative complication rates range from 10% to 40%. To improve the quality of further studies and recommendations for standardization of surgical treatment of gastric cancer and its complications, there is a need to study the differences in 90-day postoperative morbidity and mortality in different clinics and centers of the Russian Federation. conditions: Gastric Cancer conditions: Siewert Type III Adenocarcinoma of Esophagogastric Junction conditions: Stomach Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 700 type: ESTIMATED name: Elective Surgery for gastric cancer measure: the type of complications and the incidence of it sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: A.S. Loginov Moscow Clinical Scientific Center city: Moscow country: Russian Federation name: Roman Izrailov role: CONTACT name: Nikolay Semenov role: CONTACT lat: 55.75222 lon: 37.61556 facility: A.Tsyb Medical Radiological Research Centre city: Moscow country: Russian Federation lat: 55.75222 lon: 37.61556 facility: I.M. Sechenov First Moscow State Medical University city: Moscow country: Russian Federation lat: 55.75222 lon: 37.61556 facility: P.Herzen Moscow Oncological Research Institute city: Moscow country: Russian Federation name: Andrey Ryabov role: CONTACT name: Nuriddin Abdulkhakimov role: CONTACT lat: 55.75222 lon: 37.61556 facility: Petrovsky National Research Centre of Surgery city: Moscow country: Russian Federation lat: 55.75222 lon: 37.61556 facility: Vishnevsky National Medical Research Center of Surgery city: Moscow country: Russian Federation lat: 55.75222 lon: 37.61556 facility: Nizhny Novgorod Regional Clinical Oncological Dispensary city: Nizhny Novgorod country: Russian Federation lat: 56.32867 lon: 44.00205 facility: National Medical Research Centre for Oncology city: Rostov-on-Don country: Russian Federation lat: 47.23135 lon: 39.72328 facility: Petrov National Medical Research Center of Oncology city: Saint Petersburg country: Russian Federation lat: 59.93863 lon: 30.31413 hasResults: False
nctId: NCT06277895 id: KYLL-202401-047 briefTitle: VOCs in Patients With Acute Cardiogenic Chest Pain overallStatus: RECRUITING date: 2024-01-26 date: 2024-12-31 date: 2024-12-31 date: 2024-02-26 date: 2024-02-26 name: Qilu Hospital of Shandong University class: OTHER briefSummary: The goal of this observation study is to compare VOCs in cardiogenic chest pain population/health conditions, to answer：Establishment and promotion of the application system of emergency rapid detection of expiratory Volatile Organic Compounds (VOCs) in patients with acute cardiogenic chest pain
2. The relationship between abnormal VOCs (mainly aldehydes) and prognosis of patients and the correlation with Super-score for early warning of acute heart failure. conditions: Acute Coronary Syndrome conditions: Acute Aortic Syndrome studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: DIAGNOSTIC masking: NONE count: 1400 type: ESTIMATED name: VOCs measure: Baseline VOCs (aldehydes) levels in healthy population measure: MACE in patients with cardiogenic chest pain sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Qilu hospital status: RECRUITING city: Jinan state: Shandong zip: 250012 country: China name: yuan bian role: CONTACT phone: 18560084775 email: 15165110975@163.com lat: 36.66833 lon: 116.99722 hasResults: False
nctId: NCT06277882 id: Si 067/2024 briefTitle: Efficacy and Durability of Hepatitis A Vaccination in Patients With Advanced Fibrosis and Cirrhosis overallStatus: RECRUITING date: 2024-02-29 date: 2025-03-01 date: 2025-05-31 date: 2024-02-26 date: 2024-03-19 name: Mahidol University class: OTHER briefSummary: The hepatitis A virus (HAV) is a significant global public health concern. The hepatitis A virus is transmitted primarily by the faecal-oral route, leading to acute hepatitis. Symptoms include low-grade fever, anorexia, jaundice, and typically resolve without complications.
* Compared the antibody levels against the hepatitis A virus (Anti-HAV IgG) of the standard 2-dose (0, 6 months) hepatitis A vaccination regimen versus the intensive 3-dose (0, 1, 6 months) hepatitis A vaccination regimen in patients with advanced fibrosis and cirrhosis. conditions: Cirrhosis conditions: Hep A conditions: Vaccination studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 50 type: ESTIMATED name: HAVRIX measure: Post-vaccination serological response rate measure: Post-vaccination serological response measure: Post-vaccination serological response measure: Anti-hepatitis A Virus (HAV) antibody at month 1 measure: Anti-hepatitis A Virus (HAV) antibody at month 7 measure: Anti-hepatitis A Virus (HAV) antibody at 1 year sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Faculty of Medicine, Siriraj Hospital status: RECRUITING city: Bangkok Noi state: Bangkok zip: 10700 country: Thailand name: Watcharasak Chotiyaputta, Asso Prof role: CONTACT phone: 6624197281 email: watcharasak.cho@mahidol.ac.th lat: 13.76266 lon: 100.47798 hasResults: False
nctId: NCT06277869 id: PR-22146 briefTitle: Effectiveness Trial of Thermal Jacket overallStatus: RECRUITING date: 2024-03-01 date: 2024-12-22 date: 2024-12-31 date: 2024-02-26 date: 2024-03-07 name: International Centre for Diarrhoeal Disease Research, Bangladesh class: OTHER name: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh name: Directorate General of Health Services (DGHS), Bangladesh name: Poeticgem International Ltd briefSummary: Globally, over 15 million neonates are born preterm each year. They account for approximately 30% of global neonatal deaths and 19% of total neonatal deaths in Bangladesh. They usually die because they cannot maintain normal temperature due to their weight, immature skin and underdeveloped thermal regulatory capacity of the brain.
Objectives: The aim of this study is to test whether the thermal jacket can attain and maintain euthermia of preterm or LBW neonates in clinical settings of Bangladesh. conditions: Preterm Neonate conditions: Low Birthweight Neonate studyType: INTERVENTIONAL phases: PHASE2 allocation: NON_RANDOMIZED interventionModel: FACTORIAL interventionModelDescription: Stepped wedge cluster randomised trial primaryPurpose: TREATMENT masking: NONE count: 300 type: ESTIMATED name: Thermal Jacket name: Kangaroo Mother Care measure: Body temperature of preterm or low birthweight neonates maintain the euthermic range. sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Lakshmipur District Hospital status: RECRUITING city: Lakshmipur state: Chattogram zip: 3700 country: Bangladesh name: Ahmed Kabir, MBBS role: CONTACT phone: 01842587456 email: laxmipur@hospital.dghs.gov.bd lat: 22.9443 lon: 90.83005 facility: Kushtia 250 Bedded General Hospital status: RECRUITING city: Kushtia state: Khulna zip: 7000 country: Bangladesh name: Md. Rafiqul Islam, MBBS role: CONTACT phone: 01829699289 email: kushtia@hospi.dghs.gov.bd lat: 23.9028 lon: 89.11943 facility: Jamalpur 250 Beded General Hospital status: NOT_YET_RECRUITING city: Jamalpur state: Mymensingh zip: 2000 country: Bangladesh name: Muhammad Mahfuzur Rahman, MBBS role: CONTACT phone: 01716267689 email: jamalpur@hospital.dghs.gov.bd lat: 24.91965 lon: 89.94812 hasResults: False
nctId: NCT06277856 id: Aysun Eksioglu id: Ayse Akyar type: OTHER domain: Ege University briefTitle: Peer Interaction of Primiparas Sharing a Room With Multiparas With Successful Breastfeeding Experience overallStatus: RECRUITING date: 2023-09-15 date: 2024-06-15 date: 2024-09-15 date: 2024-02-26 date: 2024-02-26 name: Ege University class: OTHER briefSummary: The World Health Organization (WHO) states that peer support breastfeeding education programs are effective interventions for improving breastfeeding outcomes. In this context, the WHO's Global Strategy for Infant and Young Child Feeding recommends the implementation of "lay health worker peer counselors" and "mother-to-mother support groups" to promote and support breastfeeding. The tenth step of the Baby-Friendly Hospital Initiative also emphasizes the importance of mother-to-mother support as a successful intervention for breastfeeding. However, in our country, there have been limited studies and efforts to provide peer education and support for breastfeeding. Although various valuable studies using different educational techniques have been conducted to improve breastfeeding rates, the integration of these programs into routine clinical practice remains insufficient. This study aims to implement a peer interactive education program in postpartum rooms to bring experienced and inexperienced mothers together, as part of the hospital routine. The project will focus on the development and implementation of a peer interactive education program and will investigate its impact on the breastfeeding self-efficacy of primiparous mothers. The research follows a two-group pre-test and post-test design, is non-blind, and uses randomized controlled methodology. Initially, the hospital rooms will be rearranged to accommodate the implementation of the peer support breastfeeding education module. Researcher midwives will provide a brief training to experienced peer educator mothers who have previously breastfed.Afterwards, the peer education program will be conducted when the experienced mother and primiparous mother are together in the room. The study emphasizes improving early postpartum breastfeeding success and aims to make peer interaction a routine part of hospital practice. The feasibility of implementing peer education in hospitals will be evaluated, considering its simplicity and practicality. The impact of peer interactions on the mother's breastfeeding self-efficacy and attitudes towards breastfeeding will be assessed.
Overall, this research aims to improve breastfeeding rates by implementing peer support programs in hospital settings and evaluating the outcomes of peer interactions in terms of the mother's breastfeeding self-efficacy and attitudes towards breastfeeding. conditions: Mothers studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE maskingDescription: In order to eliminate selection bias in the study, "block randomisation" method, one of the fixed probability randomisation methods, will be used and women who meet the inclusion criteria will be distributed to the intervention and control groups. whoMasked: INVESTIGATOR count: 128 type: ESTIMATED name: Peer interaction/control measure: breastfeeding self-efficacy measure: exclusive breastfeeding rate sex: FEMALE minimumAge: 18 Years maximumAge: 49 Years stdAges: ADULT facility: Ege University status: RECRUITING city: Izmir zip: 35100 country: Turkey name: Ayşe Akyar, Midwife role: CONTACT phone: +905538507280 email: akyarayse_02@hotmail.com; lat: 38.41273 lon: 27.13838 hasResults: False
nctId: NCT06277843 id: PR-21131 briefTitle: Low-Cost and Reusable Thermal Jacket for Managing Preterm or Low Birth Weight Neonates. overallStatus: COMPLETED date: 2022-06-13 date: 2022-09-01 date: 2022-09-30 date: 2024-02-26 date: 2024-02-26 name: International Centre for Diarrhoeal Disease Research, Bangladesh class: OTHER name: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh name: Directorate General of Health Services (DGHS), Bangladesh name: Poeticgem International Ltd name: University of Dhaka briefSummary: Globally, over 15 million neonates are born preterm each year. They account for approximately 30% of global neonatal deaths and 19% of total neonatal deaths in Bangladesh. They usually die because they cannot maintain normal temperature due to their weight, immature skin and underdeveloped thermal regulatory capacity of the brain.
Objective of this study is to conduct clinical safety trial of the thermal jacket to test whether the thermal jacket can retain euthermia of preterm or LBW neonates for 2 hours. conditions: Preterm conditions: Low Birthweight conditions: Hypothermia Neonatal studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Single arm non-randomized trial primaryPurpose: TREATMENT masking: NONE count: 10 type: ACTUAL name: Thermal Jacket measure: Body temperature of preterm or low birthweight neonates and duration of time in euthermic range. sex: ALL minimumAge: 0 Hours maximumAge: 72 Hours stdAges: CHILD facility: Bangabandhu Sheikh Mujib Medical University (BSMMU) city: Dhaka zip: 1000 country: Bangladesh lat: 23.7104 lon: 90.40744 hasResults: False
nctId: NCT06277830 id: 2023P002788 briefTitle: Physical Activity Monitoring in Myasthenia Gravis overallStatus: RECRUITING date: 2024-02-14 date: 2024-06 date: 2024-06 date: 2024-02-26 date: 2024-03-04 name: Massachusetts General Hospital class: OTHER name: BioSensics briefSummary: The goal of this observational study is to evaluate the feasibility of using wearable sensor and digital technologies to measure motor and speech function in adults with autoimmune Myasthenia Gravis (MG).
Participants will wear a pendant sensor for 7 days and then participate in tablet-based and in-person myasthenia-specific physical examinations. This will be performed in concert with routine care in the Massachusetts General Hospital MG clinic. conditions: Myasthenia Gravis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 20 type: ESTIMATED name: Wearable sensor measure: Primary outcome measure: Exploratory outcome sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Massachusetts General Hospital status: RECRUITING city: Boston state: Massachusetts zip: 02114 country: United States name: Carina Stafstrom, BS role: CONTACT email: cstafstrom@mgh.harvard.edu role: CONTACT phone: 617-726-5175 lat: 42.35843 lon: -71.05977 hasResults: False
nctId: NCT06277817 id: 2021/1916 briefTitle: The Effect of Chest Physiotherapy Methods Applied Before Aspiration on Respiratory Characteristics overallStatus: COMPLETED date: 2021-05-19 date: 2021-06-25 date: 2022-10-24 date: 2024-02-26 date: 2024-02-26 name: Inonu University class: OTHER briefSummary: Physiotherapy is one of the most frequently used supportive treatments in intensive care units due to its positive effects on critically ill patients. Chest physiotherapy (GF), which constitutes the most effective part of the physiotherapy programs applied to intensive care patients under mechanical ventilation (MV) support, consists of a series of techniques aimed at clearing airway secretions, facilitating appropriate lung ventilation by increasing lung volume and respiratory muscle strength, and improving the respiratory system and gas exchange. . Of these techniques, manually applied percussion vibration and expiratory rib cage compression (EGCC) are some of the most commonly applied GF techniques in patients on MV support. This study was conducted to evaluate the effect of chest physiotherapy techniques applied before aspiration on vital signs, blood gas values and amount of secretion in patients on mechanical ventilation support. conditions: Patient Involvement studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The randomization of this study was performed by a statistical expert independent of the study, using the computer-assisted Random Allocation Rule method, which is one of the random assignment methods (http://biostatapps.inonu.edu.tr/RAY/).78 patients to be included in the study were divided into 3 groups and assigned an equal number of patients in each group according to the results of the random assignment method. In order to assign patients to research groups impartially, the research groups determined were written on papers and group assignments were made by drawing lots. Thus, the number of individuals in the groups and the probability of each patient included in the study being in either of the experimental or control groups were equalized. primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: PARTICIPANT count: 78 type: ACTUAL name: expiratory rib cage compression name: percussion vibration measure: The effect of percussion vibration on the amount of secretion measure: Effect of expiratory rib cage compression on the amount of secretion measure: Effect of percussion vibration on blood gas parameters measure: Effect of expiratory rib cage compression on blood gas parameters measure: Perküsyon vibrasyonun yaşam bulgularına etkisi measure: Effect of expiratory rib cage compression on vital signs sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Tunceli State Hospital city: Tunceli zip: 62000 country: Turkey lat: 39.09921 lon: 39.54351 hasResults: False
nctId: NCT06277804 id: LTC004-102 briefTitle: A Phase I Study of LTC004 Combin With FC in Patients With Advanced/Metastatic Malignancies Tumor overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2027-07-01 date: 2027-07-01 date: 2024-02-26 date: 2024-02-26 name: Letolab class: INDUSTRY briefSummary: This was a multicenter, open PHASE I study of LTC004 in Combination With Cyclophosphamide and Fludarabine in Patients With Advanced/Metastatic Malignancies Tumor, the study design consisting of 2 phases: Phase Ia (Phase Ia dose escalation) and Phase Ib (Phase Ib expansion). The objective of this study was to evaluate combination safety, tolerability, pharmacokinetic,pharmacodynamics characteristics, and initial efficacy in advanced malignant tumors. conditions: Adult Solid Tumor studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: NONE count: 48 type: ESTIMATED name: LTC004 in Combination With Cyclophosphamide and Fludarabine measure: Safety, tolerability and antitumor efficacy of Combination. measure: PK Characteristics and immunogenicity of Combination sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06277791 id: HStomatologyWuhan1 briefTitle: The Combination of Adebrelimab and TP Regimen for Neoadjuvant Therapy in Patients With Stage IVB Oral Squamous Cell Carcinoma overallStatus: RECRUITING date: 2023-08-19 date: 2024-07-31 date: 2025-07-31 date: 2024-02-26 date: 2024-02-26 name: Hospital of Stomatology, Wuhan University class: OTHER briefSummary: The goal of this \[type of study:clinical trial\] is to \[learn about\] in \[Clinical IVB stage oral squamous cell carcinoma patients\]. The main question it aims to answer are: