hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06350305 id: Screening for high-risk COPD briefTitle: Screening for High-risk Chronic Obstructive Pulmonary Disease overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-04-30 date: 2027-10-31 date: 2024-04-05 date: 2024-04-11 name: Henan University of Traditional Chinese Medicine class: OTHER briefSummary: This study is a multicenter cross-sectional study design aimed at screening risk factors for the combination of disease and syndrome in high-risk individuals with chronic obstructive pulmonary disease (COPD). conditions: High-risk COPD studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 3600 type: ESTIMATED name: questionnaire survey measure: COPD screening questionnaire from Terrassa (EGARPOC) measure: COPD assessment in primary care to identify undiagnosed respiratory disease and exacerbation risk questionnaire (CAPTURE) measure: COPD Assessment Test (CAT) measure: COPD screening questionnaire (COPD-Q) measure: chronic obstructive pulmonary disease diagnostic questionnaire (CDQ) measure: modified chronic obstructive pulmonary disease diagnostic questionnaire (mCDQ) measure: Simple screening questionnaire measure: lung function questionnaire (LFQ) measure: chronic obstructive pulmonary disease screening questionnaire (COPD-SQ) measure: chronic obstructive pulmonary disease population screener questionnaire (COPD-PS) measure: Chronic Obstructive Pulmonary Disease Risk Scale (COPDRS) measure: Standardised Scale of Physical Fitness in Chinese Medicine measure: Syndrome therapeutic evaluation scale of chronic obstructive pulmonary disease (COPD-STES) sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The First Affiliated Hospital of Henan University of Chinese Medicine city: Zhengzhou state: Henan zip: 450000 country: China name: yang Xie, doctor role: CONTACT phone: 0371-66248624 email: xieyanghn@163.com lat: 34.75778 lon: 113.64861 hasResults: False
nctId: NCT06350292 id: 0161464 briefTitle: SLEEP-COPE: Sleep Intervention for Oppositional Children overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-01-01 date: 2025-02-01 date: 2024-04-05 date: 2024-04-05 name: University of South Florida class: OTHER briefSummary: Children with Oppositional Defiant Disorder (ODD) are at risk for insomnia, arousal dysfunction, mood problems, and noncompliance. Cognitive behavioral treatment for insomnia (CBT-I) holds promise for improving insomnia and related concerns. Telehealth delivery will reduce the burden of in-person sessions, particularly in areas where there is low mental healthcare access. Telehealth CBT-I is efficacious in adults and children but has not been tested in children with ODD. The proposed trial is the next logical step - development and iterative testing of SLEEP-COPE, a brief dyadic telehealth CBT-I for children with ODD and their parents. conditions: Insomnia Chronic conditions: Oppositional Defiant Disorder studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 25 type: ESTIMATED name: SLEEP: COPE measure: Child Daily Sleep Diaries measure: Parent Daily Sleep Diaries measure: Child Actigraphy measure: Parent Actigraphy measure: Child Salivary Cortisol measure: Child Hair Cortisol measure: The Revised Childhood Anxiety and Depression Scale measure: PROMIS Child Sleep Disturbance measure: Alabama Parenting Questionnaire measure: Perceived Stress Scale measure: Child Disruptive Behavior Disorders Checklist measure: Beck Depression Inventory-II measure: State-Trait Anxiety Inventory measure: PROMIS Adult Sleep Disturbance measure: Pediatric Sleep Questionnaire measure: Epworth Sleepiness Scale sex: ALL minimumAge: 8 Years maximumAge: 12 Years stdAges: CHILD hasResults: False
nctId: NCT06350279 id: HSK39297-101 briefTitle: A Phase I Study to Assess the Safety,Tolerability, PK, PD, and Food Effect of HSK39297 in Healthy Subjects overallStatus: RECRUITING date: 2023-12-25 date: 2024-05-31 date: 2024-07-31 date: 2024-04-05 date: 2024-04-05 name: Haisco Pharmaceutical Group Co., Ltd. class: INDUSTRY briefSummary: This is a Phase I, randomized, subject-blinded, placebo controlled study to assess the safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD),and food effect (FE) of HSK39297 following (1) a single ascending dose (part 1), (2) 10 days of multiple ascending dose (part 2), and (3) a single dose two-period crossover FE cohort. conditions: Healthy studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 96 type: ESTIMATED name: HSK39297 measure: The number and severity of treatment emergent adverse events (TEAEs) . measure: AUC measure: Cmax measure: Tmax measure: t1/2 measure: AP change measure: Bb sex: ALL minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Beijing Tongren Hospital status: RECRUITING city: Beijing country: China name: Laichun Lu role: CONTACT lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06350266 id: 2024-0183 briefTitle: Informing Low-acuity Emergency Department Patients of Non-emergent Resources overallStatus: NOT_YET_RECRUITING date: 2024-04-22 date: 2024-12 date: 2024-12 date: 2024-04-05 date: 2024-04-05 name: Geisinger Clinic class: OTHER briefSummary: The goal of this campaign is to reduce unnecessary ED visits/encourage patients with low acuity visits to follow up with an appropriate provider and/or to seek care outside of the ED in the future. In this campaign, patients will be assigned to receive or not receive outreach following ED discharge that is aligned with the goal. Outreach will occur via a text message, as well as information added to the patient's after visit summary, and will include one or more calls to action that make patients aware of other Geisinger resources and avenues through which they can seek care outside of the ED. These may include, but are not limited to, walk-in urgent care, virtual urgent care, PCP appointments, and/or other ways in which to contact Geisinger. We will measure whether ED use differs across patients in different outreach conditions. We will also examine whether patients followed through on the message-specific calls to action in the messages differently across conditions. conditions: Emergency Service, Hospital studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE maskingDescription: Patients will be aware of their own messages but not of messages sent to other patients or in other arms. count: 8300 type: ESTIMATED name: Information about healthcare resources measure: Return to ED measure: PCP appointment scheduled measure: PCP visit measure: Telehealth appointment scheduled measure: Telehealth appointment attended measure: Urgent care visit measure: Call made to PCP measure: Any of the suggested actions taken sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06350253 id: 22-X-187 briefTitle: Comparison Of Measured To Predicted Resting Metabolism overallStatus: RECRUITING date: 2023-03-14 date: 2024-12-31 date: 2025-12-31 date: 2024-04-05 date: 2024-04-05 name: Ohio University class: OTHER briefSummary: The purpose of this study is to compare RMR values from the BIA, predicted equations, and indirect calorimetry. conditions: Body Weight studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 150 type: ESTIMATED name: Metabolic cart name: MedGem name: BIA measure: Resting metabolic rate sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Ohio University Exercise Physiology Lab status: RECRUITING city: Athens state: Ohio zip: 45701 country: United States name: Angela Hillman, PhD role: CONTACT phone: 740-593-0153 email: hillman@ohio.edu lat: 39.32924 lon: -82.10126 hasResults: False
nctId: NCT06350240 id: KUzunAkkaya briefTitle: Effects of Textured Insoles and Exercise in Children With Joint Hypermobility overallStatus: RECRUITING date: 2023-11-01 date: 2024-11-01 date: 2024-11-30 date: 2024-04-05 date: 2024-04-05 name: Gazi University class: OTHER name: TÜBİTAK briefSummary: Joint hypermobility is the condition that the joints have a greater range of motion than normal and can be observed frequently in children. In children with joint hypermobility, motor problems, tactile and proprioceptive sensory disorders can be observed. It is very important to support children with joint hypermobility with intervention programs that are rich in both motor and sensory aspects. The aim of this project is to create an exercise protocol rich in tactile, proprioceptive senses for children with joint hypermobility and to examine the effects of using textured insoles in addition to exercise on tactile sense, balance, foot load distribution and quality of life in children. conditions: Child, Only conditions: Joint Laxity conditions: Exercise conditions: Textured Insoles studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: INVESTIGATOR count: 40 type: ESTIMATED name: Exercise name: Exercise+texture insoles measure: Tactile sense measure: Foot load distribution measure: Balance measure: Foot posture measure: Quality of life assessment sex: ALL minimumAge: 5 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Gazi University status: RECRUITING city: Ankara country: Turkey name: Kamile Uzun Akkaya, Phd role: CONTACT lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06350227 id: WestChinaSU briefTitle: Impact of Different Hemostasis Methods on Ovarian Function and Fertility During Laparoscopic Ovarian Cystectomy of Benign Ovarian Cyst overallStatus: RECRUITING date: 2024-01-04 date: 2026-01 date: 2026-06 date: 2024-04-05 date: 2024-04-05 name: West China Second University Hospital class: OTHER briefSummary: The purpose of this study is to compare the impact of different hemostasis methods during laparoscopic ovarian cystectomy on ovarian function and fertility in women with benign ovarian cysts. conditions: Ovarian Cyst Benign studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 165 type: ESTIMATED name: the absorbable hemostat and suture name: electrocoagulation and suture name: suture measure: Antral Follicle Count (AFC) measure: Anti-Mullerian hormone (AMH) sex: FEMALE minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: West China Second University Hospital, Sichuan University status: RECRUITING city: Chengdu state: Sichuan country: China name: Yanru Long role: CONTACT phone: 86-13550169017 email: 2801443341@qq.com lat: 30.66667 lon: 104.06667 hasResults: False
nctId: NCT06350214 id: #2005-06; #2011-17; #2018-01 briefTitle: Physical Activity and Nutrition in Cancer Survivors overallStatus: COMPLETED date: 2007-01-01 date: 2018-12-31 date: 2018-12-31 date: 2024-04-05 date: 2024-04-05 name: West China Hospital class: OTHER briefSummary: This study aims to investigate the independent and combined associations between physical activity and nutrition condition with mortality among cancer survivors. conditions: Cancer conditions: Nutrition, Healthy conditions: Physical Inactivity studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 3100 type: ACTUAL name: physical activity and nutrition assessment measure: All-cause mortality measure: Cause-specific mortality sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06350201 id: KY2024.0124.02 briefTitle: Machine Learning-based Classification of Symptom Clusters and Online CBT overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-12-01 date: 2024-12-01 date: 2024-04-05 date: 2024-04-09 name: Wuhan Mental Health Centre class: OTHER briefSummary: To breakthrough the bottleneck identified, we will conduct a cross-sectional study to develop a symptom clustering model for depression and anxiety. A wide range of statistical methods as well as machine learning approaches were explored, and a cohesive hierarchical clustering algorithm will be used. After developing the model, a symptom-matched intervention program based on problem solving therapy will be formulated. We are supposed to examine whether its use for personalizing symptom-matched psychological treatment can lead to improved patient outcomes, compared with usual care. This project is expected to provide a new and precise method for the emotion management, which will provide a standardized intervention pathway combining screening with treatment for the management of depression symptom and anxiety symptom. A preciser intervention matched to individual symptoms may provide important insight in improving patient outcome as well as a standardized mood management pathway targeting to the early detection and intervention for community residents. conditions: Depression and Anxiety Symptom studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 120 type: ESTIMATED name: cognitive behavior therapy name: control group measure: The Patient Health Questionnaire (PHQ-9) measure: 7-tiem Generalized Anxiety Disorder Scale,GAD-.7 sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06350188 id: ECM#2024-506 briefTitle: Efficacy of Kinesiotape on Treatment of Nonspecific Cardiac Chest Pain overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-22 date: 2024-06-22 date: 2024-07-22 date: 2024-04-05 date: 2024-04-05 name: Cairo University class: OTHER briefSummary: purpose of the study To investigate the effect of Kinesio-tape on treatment of nonspecific cardiac chest pain conditions: Nonspecific Cardiac Chest Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 30 type: ACTUAL name: experimental name: traditional measure: PAIN USING VIISUSL ANALOGE SCALE measure: PERSSURE PAIN THRESHOLD measure: SHOULDER RANGE OF MOTION measure: shoulder pain and disability sex: ALL minimumAge: 20 Years maximumAge: 35 Years stdAges: ADULT facility: Huda Badr Abd Elhamed city: Cairo country: Egypt lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06350175 id: 2212697123 briefTitle: Emergency Department Management of Tobacco Use Disorder overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-03 date: 2025-06 date: 2024-04-05 date: 2024-04-16 name: West Virginia University class: OTHER briefSummary: The objective of this study is to determine the effectiveness of ED initiated NRT on tobacco cessation point abstinence rates as reported by patients at 2 weeks and 1 month post randomization, and continued abstinence rates at 3 months compared to standard of care therapy. conditions: Tobacco Use Disorder conditions: Tobacco Use Cessation studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: INVESTIGATOR count: 100 type: ESTIMATED name: Nicotine Replacement Therapy Agent name: West Virginia Quit Line measure: Percentage of Continued Abstinence Rate (2 weeks) measure: Percentage of Continued Abstinence Rate (1 month) measure: Percentage of Continued Abstinence Rate (3 months) measure: Patient Health Questionnaire 2 (Baseline) measure: Patient Health Questionnaire 2 (3 months from baseline) measure: Heaviness of Smoking Index (Baseline) measure: Heaviness of Smoking Index (3 months from baseline) measure: Richmond Test (Baseline) measure: Richmond Test (3 months from baseline) sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: West Virginia University city: Morgantown state: West Virginia zip: 26505 country: United States lat: 39.62953 lon: -79.9559 hasResults: False
nctId: NCT06350162 id: ASTRUM-LC12 briefTitle: Testing the Addition of Radiation Therapy to the Immune Therapy Treatment for ES-SCLC overallStatus: RECRUITING date: 2023-10-18 date: 2024-12-31 date: 2025-12-31 date: 2024-04-05 date: 2024-04-05 name: Zhejiang Cancer Hospital class: OTHER briefSummary: This phase II trial compares the effect of adding radiation therapy to the usual maintenance therapy with Serplulimab versus Serplulimab alone in patients who have already received Serplulimab plus chemotherapy for the treatment of extensive stage small cell lung cancer . conditions: Extensive Stage Lung Small Cell Cancer studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 100 type: ESTIMATED name: Serplulimab name: Chest Radiation measure: 1-year Progression-free survival rate measure: Progression-free survival (PFS) measure: Overall survival (OS) measure: Duration of response (DOR) measure: Disease control rate (DCR) measure: Number of participants with treatment-related adverse events as assessed by CTCAE v5.0 sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Zhejiang Cancer Hospital status: RECRUITING city: Hangzhou country: China name: jing Qin role: CONTACT lat: 30.29365 lon: 120.16142 hasResults: False
nctId: NCT06350149 id: STUDY00004637 id: 1R21DK128731-01A1 type: NIH link: https://reporter.nih.gov/quickSearch/1R21DK128731-01A1 briefTitle: A Pilot and Feasibility Study to Evaluate High vs Low Glycemic Index Mixed Meal Tolerance Test in Adolescents and Young Adults With Cystic Fibrosis overallStatus: RECRUITING date: 2024-03-22 date: 2025-09 date: 2025-09 date: 2024-04-05 date: 2024-04-05 name: Emory University class: OTHER name: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) briefSummary: The goal of this study is to determine the extent to which excess dietary simple sugars serve as a secondary mediating factor in Cystic fibrosis-related diabetes (CFRD) development. The main questions it aims to answer are:
Participants will be randomized to a mixed diet and blood will be drawn before and after the mixed meal challenge. conditions: Cystic Fibrosis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: FACTORIAL primaryPurpose: OTHER masking: NONE count: 40 type: ESTIMATED name: Sugar Sweetened Beverages (SSB) name: Hi GI name: Lo GI measure: Recruitment Rate measure: Refusal Rate measure: Investigator Fidelity measure: Participant Fidelity measure: Acceptability measure: Retention Rates measure: Recruitment measure: Change in plasma Cysteine (Cys) measure: Change in plasma Cystine (CySS) measure: Change in plasma Glutathione (GSH) measure: Change in plasma Glutathione Disulfide (GSSG) measure: Change in redox potentials (EhCys/ CySS and EhGSH/GSSG) measure: Insulinogenic index measure: Whole body insulin sensitivity index (WBISI-Matsuda) measure: Disposition Index measure: Change in plasma Eh Cys/CySS measure: Change in incremental glucose AUC measure: Changes in Plasma insulin measure: Changes in Plasma C-peptide measure: Changes in Plasma Glucagon measure: Changes in Plasma Incretins: glucagon-like peptide-1 (GLP-1) measure: Changes in Plasma Incretins: total glucose-dependent insulinotropic polypeptide (GIP) sex: ALL minimumAge: 12 Years maximumAge: 21 Years stdAges: CHILD stdAges: ADULT facility: Center for Advanced Pediatrics: Emory Healthcare status: RECRUITING city: Atlanta state: Georgia zip: 30329 country: United States name: Tanicia Daley, MD role: CONTACT phone: 404-785-5437 email: tanicia.daley@emory.edu name: Arlene Stecenko, MD role: CONTACT phone: 404-727-1460 email: astecen@emory.edu name: Tanicia Daley, MD role: PRINCIPAL_INVESTIGATOR name: Jessica Alvarez, PhD role: SUB_INVESTIGATOR name: Arlene Stecenko, MD role: SUB_INVESTIGATOR lat: 33.749 lon: -84.38798 hasResults: False
nctId: NCT06350136 id: 2024/05-37 briefTitle: The Effect of Self-Management Support Provided to Hypertension Patients Affected by the Earthquake Via Tele-Nursing on Patients' Treatment Compliance and Self-Care Management overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2024-12-01 date: 2025-06-01 date: 2024-04-05 date: 2024-04-08 name: Firat University class: OTHER briefSummary: This important research includes a randomized controlled trial evaluating the potential of self-management support provided via telenursing to earthquake-affected hypertension patients to improve patients' treatment adherence and overall self-care management. This study will be carried out at Fırat University Hospital and will cover a wide range of effects on health outcomes in individuals receiving hypertension treatment. The sample selected from hypertension patients, which constitute the population of the research, was based on predetermined power analysis criteria. It has been determined that at least 51 hypertension patients should be included in each of the intervention and control groups, and accordingly, a total of 150 hypertension patients will be included in the study.
. The results obtained within this framework may provide guidance in the development and implementation of Turkey's health policies, and may also shed light on strategies for the management of other similar health problems. On the other hand, strengthening the digital health infrastructure and effective management of chronic diseases, which are among the health-related targets of the Development Plan, further emphasize the importance of this research. The success of the self-management model supported by tele-nursing can serve as an example in the integration of digital health technologies into Turkey's healthcare system and be an important step towards achieving strategic goals in this field. conditions: With Tele-Nursing studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: PARTICIPANT count: 150 type: ESTIMATED name: With Tele-Nursing measure: Hill-Bone Hypertension Treatment Compliance Scale measure: Self-Care Management Scale in Chronic Diseases; measure: Psychological Impact of Earthquake Scale: measure: Earthquake Stress Coping Strategies Scale sex: ALL minimumAge: 55 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06350110 id: ESBI202492 briefTitle: Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE) acronym: BAH242 overallStatus: NOT_YET_RECRUITING date: 2024-11-10 date: 2025-12-10 date: 2025-12-28 date: 2024-04-05 date: 2024-04-05 name: Essen Biotech class: OTHER briefSummary: This study is a preliminary investigation, with a single-group design, not randomized and transparent, focusing on treatment. Its purpose is to identify the highest dose of BH002 injection (CD19-BCMA CAR-T cells) that patients suffering from resistant systemic lupus erythematosus can tolerate. conditions: Systemic Lupus Erythematosus conditions: Lupus Nephritis conditions: Autoimmune Diseases conditions: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis conditions: Granulomatous Polyangiitis conditions: Microscopic Polyangiitis conditions: Systemic Sclerosis conditions: Idiopathic Inflammatory Myopathies conditions: Sjogren's Syndrome studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Single Group Assignment