hackint0sh/New-Dataset huggingface dataset:
Researchers will compare SafeCare Kenya to care as usual by community health volunteers to see if SafeCare Kenya families show improvements in parent interaction skills, safety and health knowledge, potential for child abuse, child behavior problems, child injuries, parenting stress, and child and parent quality of life. conditions: Child Maltreatment conditions: Parenting studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 369 type: ESTIMATED name: SafeCare Kenya name: Care as Usual by Community Health Volunteers measure: Change from Baseline in score on Child Planned Activities Training (cPAT) at 6 months measure: Change from Baseline in score on Child Planned Activities Training (cPAT) at 18 months measure: Change from Baseline in scores on Parenting Young Children (PARYC) at 6 months measure: Change from Baseline in scores on Parenting Young Children (PARYC) at 18 months measure: Change from Baseline in score on How to Keep your Child Safe and Healthy Quiz at 6 months measure: Change from Baseline in score on How to Keep your Child Safe and Healthy Quiz at 18 months measure: Change from Baseline in score on Brief Child Abuse Potential Inventory (BCAPI) at 6 months measure: Change from Baseline in score on Brief Child Abuse Potential Inventory (BCAPI) at 18 months measure: Change from Baseline in score on Child Behavior Checklist (CBCL) at 6 months measure: Change from Baseline in score on Child Behavior Checklist (CBCL) at 18 months measure: Change from Baseline in scores on Parenting Stress Index at 6 months measure: Change from Baseline in scores on Parenting Stress Index at 18 months measure: Change from Baseline in score on Childhood injuries at 6 months measure: Change from Baseline in score on Childhood injuries at 18 months measure: Change from Baseline in score on Child Quality of Life at 6 months measure: Change from Baseline in score on Child Quality of Life at 18 months measure: Change from Baseline in score on Parent Quality of Life at 6 months measure: Change from Baseline in score on Parent Quality of Life at 18 months measure: Client satisfaction measure: Provider fidelity measure: Parent Interview measure: Provider Interview measure: Trainer Interview measure: Stakeholder Interview measure: Readiness Assessment for the Prevention of Child Maltreatment (RAP-CM) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Africa Mental Health Research and Training Foundation status: RECRUITING city: Nairobi country: Kenya name: Victoria Mutiso, PhD role: CONTACT phone: (254) 202 651 360 email: vmutiso@amhf.or.ke name: Christine Musyimi, PhD role: CONTACT phone: (254) 202 651 360 email: christine.musyimi@amhf.or.ke name: David Ndetei, MD role: PRINCIPAL_INVESTIGATOR lat: -1.28333 lon: 36.81667 hasResults: False
nctId: NCT06363682 id: 2023PI225 briefTitle: Interventional Reference Levels (IRL) in Digestive Endoscopy acronym: EndoscopX overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-06-11 date: 2024-06-11 date: 2024-04-12 date: 2024-04-12 name: Central Hospital, Nancy, France class: OTHER briefSummary: Scopy uses X-rays and is not without risk (deterministic and stochastic effects) for the patient and the nursing staff present in the room at the time of an endoscopic procedure requiring its use: its use must be reasoned with a benefit/risk balance in favour of carrying out the interventional procedure. In France, there is currently no multicentre study exploring the radiation doses used for each type of endoscopic procedure.
* Radiation protection assessment for workers conditions: Each Endoscopic Intervention Using X-rays studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 1000 type: ESTIMATED name: ERCP name: endoscopic ultrasound name: gastroscopy name: Colonoscopy name: placement of a nasojejunal tube measure: To define IRL (interventional reference levels) adapted to each type of endoscopic procedure. measure: Application of regulatory texts measure: Assessment of patient radiation protection measure: Radiation protection assessment for workers sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hospital University of Nancy city: Nancy state: Meurthe-et-Moselle zip: 54000 country: France name: MUNIER W Munier Wendy role: CONTACT phone: +3383155457 email: w.munier@chru-nancy.fr name: CHEVAUX JB Doctor CHEVAUX Jean-Baptiste, PhD role: PRINCIPAL_INVESTIGATOR lat: 48.68439 lon: 6.18496 hasResults: False
nctId: NCT06363669 id: 1_CAF_AWF briefTitle: Effects of Caffeine-based Supplement on Physical Performance overallStatus: COMPLETED date: 2018-01-15 date: 2024-03-30 date: 2024-03-30 date: 2024-04-12 date: 2024-04-12 name: University School of Physical Education, Krakow, Poland class: OTHER briefSummary: The aim of the study was to determine the acute effects of multi-ingredient pre-workout supple-ment (MIPS) containing: beta-alanine, taurine, caffeine, L-tyrosine, and cayenne pepper (capsaicin) on physical performance in untrained men conditions: Muscle Power studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: DIAGNOSTIC masking: SINGLE whoMasked: PARTICIPANT count: 12 type: ACTUAL name: multi-ingredient pre-workout dietary supplement (caffeine-based) measure: anaerobic power measure: aerobic power sex: MALE minimumAge: 19 Years maximumAge: 30 Years stdAges: ADULT facility: University School of Physical Education in Cracow city: Krakow zip: 31-571 country: Poland lat: 50.06143 lon: 19.93658 hasResults: False
nctId: NCT06363656 id: 76455623.5.0000.0068 briefTitle: Assessment of Smartwatch SAMSUNG to Monitor Sleep Quality: an Observational Prospective Study - SleepEx2 Protocol acronym: SLEEP-EX2 overallStatus: RECRUITING date: 2024-02-15 date: 2024-05-28 date: 2024-07-30 date: 2024-04-12 date: 2024-04-26 name: University of Sao Paulo General Hospital class: OTHER name: Samsung Eletrônica da Amazônia Ltda name: Academic Research Organization of Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP briefSummary: The goal of this study is to learn if a smartwatch is effective to identify factors related to sleep quality and habits of adults (30 years old or more), enabling the improvement and/or creation of instruments to assess overall health status and sleep quality.
- Does the smartwatch application (software) indicate sleep habits and measure sleep quality in accordance to the standardized clinical instruments commonly used to assess sleep? conditions: Insomnia conditions: Sleep Initiation and Maintenance Disorders conditions: Health Status conditions: Wearable Electronic Devices conditions: Sleep studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 158 type: ESTIMATED name: Wears the smartwatch during the sleep time to capture sleep characteristics and answer questionaires measure: Concordance between the smartwatch application and clinical assessment sex: ALL minimumAge: 30 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Instituto do Coracao do Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo status: RECRUITING city: São Paulo zip: 05403-900 country: Brazil name: ARO-InCor Academic Research Organization Office role: CONTACT phone: +55 11 2661-5795 email: aro@incor.usp.br name: Daniel Queiroz, PhD role: CONTACT phone: +55 11 9-4138-5473 email: daniel.queiroz@incor.usp.br name: Geraldo Lorenzi Filho, MD, PhD role: PRINCIPAL_INVESTIGATOR lat: -23.5475 lon: -46.63611 hasResults: False
nctId: NCT06363643 id: Prehab01 briefTitle: Lower Limb Arthroplasty: Effects of a Tele Prehabilitation Program With Indirect Electrostimulation. overallStatus: NOT_YET_RECRUITING date: 2024-04-22 date: 2024-07-26 date: 2024-07-26 date: 2024-04-12 date: 2024-04-12 name: University of Pavia class: OTHER briefSummary: Preoperative fitness is known to predict postoperative outcomes following lower limb arthroplasty, but many patients, especially the most fragile, arrive at surgery with reduced mobility and functional capacity.
Prehabilitation (Prehab) encompasses a series of interventions that are intended to help patients improve their physical state and psychological well-being pre-intervention to reduce the days of hospitalization and the number of post-operative complications. Patients who participate in Prehab require less postoperative care and consequently have less impact on the cost of the healthcare system. However, adherence to a face-to-face program is usually poor and presents both organizational and psychophysical barriers. In the last years, telerehabilitation has proven to be a viable alternative to face-to-face treatment and has already been adopted for the Prehab. Electrostimulation (ESM) is regularly used successfully in clinical settings for the recovery of muscle tone in patients with orthopedic pathologies. In addition, it has already been used for Prehab, showing an increase in muscle strength and a decrease in postoperative hospital stay following knee arthroplasty. Also Exercise offers benefits in the treatment of orthopedic patients because improve: strength, cardiovascular fitness, functional capacities and quality of life. Therefore, in a group of patients who are candidates for elective lower limb arthroplasty surgery, it was decided to evaluate the effects of a Tele Prehab program, based on the ESM, and compare them with those of an Tele Prehab exercise program, equal in dose and duration. The proposal differs from those present in the literature for complete administration in telerehabilitation, including evaluations. conditions: Osteo Arthritis Knee and Hip conditions: Lower Limb Arthroplasty studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 44 type: ESTIMATED name: ELECTROSTIMULATION (ES) name: EXERCISE (C) measure: Change from baseline in functional capacities on 30 Seconds Chair Stand Test (30CST) at week 4 measure: Change from baseline in functional capacities on Timed Up and Go test (TUG) at week 4. sex: ALL minimumAge: 55 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: "Città di Pavia Healthcare Institute" city: Pavia zip: 27100 country: Italy name: Luca Marin role: CONTACT phone: 0382 433658 phoneExt: +39 email: luca.marin@unipv.it name: Luca Marin role: PRINCIPAL_INVESTIGATOR name: Matteo Chiodarono role: SUB_INVESTIGATOR lat: 45.19205 lon: 9.15917 hasResults: False
nctId: NCT06363630 id: CA073-1000 briefTitle: A Study to Evaluate the Effect of Cytochrome P450 (CYP) 3A Inhibitor (Itraconazole) and Inducer (Rifampin) on the Drug Levels of Golcadomide (BMS-986369) in Healthy Participants overallStatus: NOT_YET_RECRUITING date: 2024-04-16 date: 2024-08-19 date: 2024-08-19 date: 2024-04-12 date: 2024-04-12 name: Celgene class: INDUSTRY briefSummary: The purpose of this study is to evaluate the drug-drug interaction (DDI) potential of coadministration of itraconazole or rifampin on the single dose drug levels of golcadomide. conditions: Healthy Volunteers studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: NONE count: 36 type: ESTIMATED name: Itraconazole name: Rifampin name: Golcadomide measure: Maximum observed plasma concentration (Cmax) measure: Area under the plasma concentration-time curve from time zero to time of the last quantifiable concentration (AUC(0-T)) measure: Area under the plasma concentration-time curve from time zero extrapolated to infinite time (AUC(INF)) measure: Number of participants with adverse events (AEs) measure: Number of participants with physical exam abnormalities measure: Number of participants with vital sign abnormalities measure: Number of participants with clinical laboratory safety test abnormalities measure: Number of participants with electrocardiogram abnormalities measure: Number of participants with concomitant medications measure: Number of participants with concomitant procedures measure: Time of maximum observed plasma concentration (Tmax) measure: Apparent terminal phase half-life (T-HALF) measure: Apparent total body clearance (CLT/F) measure: Apparent volume of distribution (Vz/F) sex: ALL minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: Local Institution - 0001 city: Lenexa state: Kansas zip: 66219 country: United States name: Site 0001 role: CONTACT lat: 38.95362 lon: -94.73357 hasResults: False
nctId: NCT06363617 id: CSAPG-58 briefTitle: Implementation of the Fatty Liver Index in Primary Care acronym: FLI-AP overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-05 date: 2024-04-12 date: 2024-04-15 name: Consorci Sanitari de l'Alt Penedès i Garraf class: OTHER briefSummary: This trial aims to evaluate the impact on cardiovascular risk control in individuals in risk of being affected by hepatic steatosis through the implementation of a screening test (Fatty Liver Index) in Primary Care. Medical teams in a primary care center will be divided into 2 groups, with one group using the screening test in their clinical practice. The number of interventions on cardiovascular risk occurring in patients attended by each group of medical teams will be evaluated and compared. conditions: Hepatic Steatosis conditions: Overweight and Obesity studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 434 type: ESTIMATED name: FLI measure: Lifestyle Intervention measure: Low-density lipoprotein cholesterol measure: Triglycerides measure: Gamma-glutamyl transpeptidase measure: Medical and nursing visits measure: Analytical checks in the first year measure: Lipid-lowering drugs measure: Healthcare spending measure: FLI administration sex: ALL minimumAge: 14 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Centro de Salud Vilanova i la Geltrú 3 Baix A Mar city: Vilanova I La Geltrú state: Barcelona country: Spain name: M Carmen Rosas, MD role: CONTACT phone: +34 938 10 30 03 email: mrosas@csapg.cat name: Noemí Casaponsa role: CONTACT phone: +34 938960026 phoneExt: 43197 email: recerca@csapg.cat name: M Carmen Rosas, MD role: PRINCIPAL_INVESTIGATOR lat: 41.22392 lon: 1.72511 hasResults: False
nctId: NCT06363604 id: XHEC-C-2023-128-2 briefTitle: Evaluation of PWI Assisted by Marshall Ethanolization in Ablation of Persistent Atrial Fibrillation overallStatus: RECRUITING date: 2023-12-01 date: 2026-09 date: 2026-11 date: 2024-04-12 date: 2024-04-12 name: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine class: OTHER briefSummary: This is a prospective, randomized controlled, single-blind, multi-center clinical trial study aiming to investigate whether the strategy of posterior wall isolation (PWI) assisted by vein of Marshall ethanol infusion (VOMEI) could improve the success rate of persistent atrial fibrillation ablation. conditions: Atrial Fibrillation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A total of 260 participants with persistent AF who undergo radiofrequency catheter ablation and received VOMEI + PVI will be randomized assigned to two groups at 1:1 ratio.
Group 0 (Control): VOMEI + PVI + linear ablation of mitral isthmus. Group 1 (Experimental): VOMEI + PVI + linear ablation of mitral isthmus + PWI primaryPurpose: TREATMENT masking: SINGLE maskingDescription: This study used a single-blind design for the subjects. A statistician created a random sequence of numbers using a randomization scheme. The sequence was then placed in opaque coded envelopes and sealed in numerical order. When a patient met the inclusion and exclusion criteria and was assigned a number, the researcher notified the manager to obtain the corresponding envelope and perform the intervention according to the grouping plan inside the envelope. Group 0 correspond to the control group not receiving PWI isolation, while group 1 correspond to the experimental group for PWI isolation. whoMasked: PARTICIPANT count: 260 type: ESTIMATED name: VOMEI + PVI + linear ablation of mitral isthmus name: Posterior wall isolation measure: Recurrence of atrial arrhythmias measure: Procedural complications sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Xinhua Hospital, Shanghai Jiao Tong University status: RECRUITING city: Shanghai state: Shanghai zip: 200092 country: China name: Mu Chen role: CONTACT phone: +86 021 25077275 email: chenmu@xinhuamed.com.cn lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06363591 id: Wise vs wide briefTitle: Single- vs Two-staged Excisions of Thin Melanoma acronym: WvW overallStatus: NOT_YET_RECRUITING date: 2024-10-01 date: 2034-12-31 date: 2034-12-31 date: 2024-04-12 date: 2024-04-15 name: Vastra Gotaland Region class: OTHER_GOV name: Stockholm Region name: Region Skane name: Region Västerbotten name: Region Örebro County name: Blekinge County Council Hospital name: Region Östergötland name: Dalarna County Council, Sweden briefSummary: The overall aim of this national, multicenter, prospective, randomized, and controlled study is to enhance the management of patients with thin melanoma (≤1 mm Breslow thickness). The investigators hypothesize that wide local excisions (WLEs) following complete excision of thin melanoma do not affect the risk of recurrence, defined as the occurrence of local, regional, distant disease, or melanoma-specific death during a 5- to 10-year follow-up period. conditions: Melanoma (Skin) conditions: Surgery studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Patients with thin (≤1.0 mm) invasive melanomas excised with a histopathological margin ≥1.5 mm will be offered to participate following informed consent and randomization (1:1) to either:
2. Experimental treatment with no WLE. primaryPurpose: TREATMENT masking: NONE count: 2486 type: ESTIMATED name: Wise vs wide measure: Recurrence rate at 5 years. measure: Recurrence rate at 10 years. measure: Postoperative complications measure: Scar length, width and quality measure: Scar length, width and quality measure: Patients' quality of life measure: Patient satisfaction measure: Patients' quality of life measure: Patient satisfaction measure: Patients' quality of life measure: Patient satisfaction measure: Direct and indirect costs per patient sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06363578 id: 36264PR604/3/24 briefTitle: Different Doses of Dexmedetomidine in External Oblique Intercostal Plane Block in Splenectomy overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2024-10-01 date: 2024-10-01 date: 2024-04-12 date: 2024-04-12 name: Tanta University class: OTHER briefSummary: The aim of this study is to compare the analgesic effects of different doses of dexmedetomidine as an adjuvant in external oblique intercostal plane block (EOIPB) in splenectomy. conditions: Dexmedetomidine conditions: External Oblique Intercostal Plane Block conditions: Splenectomy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 50 type: ESTIMATED name: Dexmedetomidine 0.5 μg/kg name: Dexmedetomidine 1 μg/kg measure: Time to the 1st rescue analgesia measure: Intraoperative fentanyl consumption measure: Total morphine consumption measure: Degree of pain measure: Heart rate measure: Mean arterial pressure measure: The incidence of adverse events sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Tanta University city: Tanta state: El-Gharbia zip: 31527 country: Egypt name: Mohammed S Elsharkawy, MD role: CONTACT phone: 00201148207870 email: mselsharkawy@med.tanta.edu.eg name: Saad A Moharam, MD role: PRINCIPAL_INVESTIGATOR lat: 30.78847 lon: 31.00192 hasResults: False
nctId: NCT06363565 id: MN-2022-11 briefTitle: Effects of Supplementation of Compound Nutrients on Plasma Homocysteine in Chinese Adults overallStatus: RECRUITING date: 2023-06-01 date: 2025-12-31 date: 2025-12-31 date: 2024-04-12 date: 2024-04-12 name: Sun Yat-sen University class: OTHER briefSummary: The purpose of this study is to determine whether supplementation of compound nutrients, including folic acid, vitamin B6, vitamin B12, and betaine, will decrease the level of plasma homocysteine in Chinese adults with homocysteine levels above 10 μmol/L. conditions: Homocysteine studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 220 type: ESTIMATED name: supplementation of compound nutrients name: placebo control measure: levels of homocysteine sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: SunYat-sen University status: RECRUITING city: Guangzhou state: Guangdong zip: 510080 country: China name: Zhu Huilian role: CONTACT lat: 23.11667 lon: 113.25 hasResults: False
nctId: NCT06363552 id: WETARI briefTitle: A Study of SC-0191 in Subjects With Metastatic Colorectal Cancer overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-04 date: 2025-12 date: 2024-04-12 date: 2024-04-12 name: Tianshu Liu class: OTHER briefSummary: The goal of this clinical trial is to evaluate the preliminary safety and efficacy of SC0191 as single agent or in combination with bevacizumab or 5-FU/LV in advanced colorectal cancer. conditions: Metastatic Colorectal Cancer studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 36 type: ESTIMATED name: SC0191 name: SC0191 + Bevacizumab name: SC0191 + 5-FU/LV measure: Objective Response Rate measure: Incidence and Severity of Dose Limiting Toxicities (DLTs) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Zhongshan Hospital Affiliated to Fudan University city: Shanghai state: Shanghai zip: 200032 country: China lat: 31.22222 lon: 121.45806 hasResults: False