hackint0sh/New-Dataset huggingface dataset:
Patients who are diagnosed with pancreatic tumor based on preoperative radiographic findings and will undergo radical resection are included in this clinical study. PCLE will be used in surgery to identify tumor is malignant or not, and surgeons will decide procedures of surgery based on outcomes of PCLE. In this present study, clinical trials will be divided into two phases. In the first phase, based on the definitive postoperative pathologic diagnosis, characteristic imaging structures that were collected by PCLE will be identified and primary diagnostic imaging criteria for pancreatic cancer would be developed. In the second phase, this criterion will be used for rapid intraoperative diagnosis of pancreatic cancer and predicting status of resection margin. In addition, accuracy of PCLE will be verified based on postoperative pathologic reports. conditions: Pancreatic Cancer conditions: Diagnosis conditions: Pancreatoduodenectomy conditions: Distal Pancreatectomy studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Patients diagnosed with pancreatic tumours will undergo surgical resection, and PCLE will be used for identifying the behaviour of tumours (benign or malignant neoplasms) and predicting the status of resection margin. primaryPurpose: TREATMENT masking: NONE count: 200 type: ESTIMATED name: probe confocal laser endomicroscopy measure: diagnostic efficacy measure: Rate of R0 resection sex: ALL minimumAge: 18 Years maximumAge: 90 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Huadong Hospital affiliated to Fudan University status: RECRUITING city: Shanghai state: Shanghai zip: 200040 country: China name: Chunjing Li, M.S role: CONTACT phone: 14790068967 email: Lcj1479006@163.com name: Chongyi Jiang, M.D role: CONTACT phone: +8618101802916 email: jiangzhongyi9@126.com lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06289790 id: 16/BW/2023' briefTitle: Erector Spinae Plane (ESP) Block vs Intravenous Lignocaine Infusion in (VATS) overallStatus: NOT_YET_RECRUITING date: 2024-02-26 date: 2024-11-07 date: 2024-11-07 date: 2024-03-04 date: 2024-03-04 name: Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland class: OTHER briefSummary: The goal of this clinical trial is to compare analgesic efficacy of erector spinae plane (ESP) block vs intravenous lignocaine infusion in video- assisted thoracoscopy (VATS. The main goals are to compare post- operative pain scores and cumulative post- operative opioid doses in both groups conditions: Thoracic Surgery, Video-Assisted studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Patient and nursing staff will be blinded to the performed intervention. PI and performing anaesthesiologist will not be blinded. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 60 type: ESTIMATED name: Erector Spinae Plane (ESP) block name: Lignocaine measure: pain score on numerical rating score measure: cumulative opioid dose measure: incidence of severe hypotension measure: incidence of nausea and vomiting measure: incidence of priuritis measure: incidence of local anaesthetic systemic toxicity symptoms measure: intra-operative cumulative opioid dose measure: time to discharge from hospital sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: National Medical Institute of the Ministry of the Interior and Administration city: Warsaw state: Mazowieckie zip: 02-507 country: Poland role: CONTACT phone: 722 14 50 phoneExt: (47) email: anestezja@cskmswia.gov.pl name: Antoni Okniński, MD role: PRINCIPAL_INVESTIGATOR name: Iwona Pikto-Pietkiewicz, MD role: SUB_INVESTIGATOR lat: 52.22977 lon: 21.01178 hasResults: False
nctId: NCT06289777 id: aortic remodeling briefTitle: Aortic Remodeling After Endovascular Management of Type B Aortic Dissection. overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2026-03-01 date: 2026-04-01 date: 2024-03-04 date: 2024-03-04 name: Assiut University class: OTHER briefSummary: Assess the clinical outcome, morphological changes and behaviour of type B aortic dissection after endovascular repair. conditions: Type B Aortic Dissection studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30 type: ESTIMATED name: TEVAR measure: Analysis of aortic remodeling measure: technical success sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Faculty of Medicine city: Asyut zip: 71515 country: Egypt lat: 27.18096 lon: 31.18368 hasResults: False
nctId: NCT06289764 id: 7/02/2024/131 briefTitle: The Effect of Aromatherapy Application With Bergamot and Grapefruit Essential Oils on PMS acronym: Aromatherapy overallStatus: RECRUITING date: 2024-02-01 date: 2024-04-20 date: 2024-05-30 date: 2024-03-04 date: 2024-03-04 name: Esra ÖZER class: OTHER name: KTO Karatay University briefSummary: Aromatherapy is;the science of using highly concentrated essential oils or essences distilled from plants to take advantage of their therapeutic properties. Essential oils or essences are obtained from various parts of plants (root, leaf, flower, bark, fruit) and used therapeutically for physical and psychological well-being.
Although the use of aromatherapy in womens health is widespread, there is no study comparing bergamot and grapefruit essential oils. The aim of this study was to determine the effect of aromatherapy with bergamot and grapefruit essential oils on premenstrual syndrome and menstrual symptoms. conditions: Premenstrual Syndrome-PMS studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 90 type: ESTIMATED name: Bergamot Essential Oil name: Grapefruit Essential Oil name: Sweet almond oil measure: Premenstrual syndrome scale (PMS) measure: Menstrual Symptom Scale sex: FEMALE minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: Ankara Medipol Unıversty status: RECRUITING city: Ankara state: Altındağ zip: 06000 country: Turkey name: Esra ÖZER, Asisst. Prof. role: CONTACT phone: +905433630475 email: esraozellllll@gmail.com name: Şerife İrem DÖNER, research assistant role: SUB_INVESTIGATOR name: Hafize DAĞ TÜZMEN, lecturer role: PRINCIPAL_INVESTIGATOR lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06289751 id: NACI-CerV-004 briefTitle: Neoadjuvant Chemoimmunotherapy and Extrafascial Hysterectomy for IB2 Cervical Cancer overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2026-03-01 date: 2031-01-01 date: 2024-03-04 date: 2024-03-04 name: Tongji Hospital class: OTHER name: The First Affiliated Hospital of China University of Science and Technology (Anhui Provincial) name: Women Hospital, School of Medicine, Zhejiang University name: Southwest Hospital, China name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University name: Sichuan Cancer Hospital and Research Institute name: Qilu Hospital of Shandong University name: Beijing Friendship Hospital name: Tianjin Medical University name: West China Second University Hospital name: Xiangya Hospital of Central South University name: Gansu Provincial Maternal and Child Health Care Hospital name: Zhejiang Cancer Hospital name: Shengjing Hospital briefSummary: This study is an exploratory clinical trial to investigate the feasibility of neoadjuvant chemoimmunotherapy plus extrafascial hysterectomy and pelvic lymph node dissection in patients with stage IB2 (2018 FIGO) cervical cancer and to observe the response rate to treatment, adverse effects and complications, and to assess the survival rate of patients. conditions: Cervical Cancer conditions: Neoadjuvant Chemoimmunotherapy conditions: Radical Hysterectomy conditions: Fertility Preservation studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: a multicentre, single-arm, phase 2 trial primaryPurpose: TREATMENT masking: NONE count: 50 type: ESTIMATED name: Cadonilimab name: Paclitaxel-albumin name: Cisplatin name: Extrafascial hysterectomy measure: Percentage of patients meeting ConCerV criteria measure: Objective Response Rate, ORR measure: Proportion of patients requiring postoperative adjuvant therapy measure: Number of Participants with Treatment-Emergent Adverse Events as assessed by CTCAE v4.0 measure: the surgical complication measure: Pathologic Complete Response measure: Overall survival, OS measure: progression-free survival, PFS sex: FEMALE minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology city: Wuhan state: Hubei zip: 430030 country: China name: Gang Chen role: CONTACT phone: 086-027-8362 email: gumpc@126.com name: Jing Chen role: CONTACT phone: 086-027-8362 email: chenjing3223@126.com name: Gang Chen role: PRINCIPAL_INVESTIGATOR name: Kezhen Li role: PRINCIPAL_INVESTIGATOR lat: 30.58333 lon: 114.26667 hasResults: False
nctId: NCT06289738 id: ICF in Takayasu Arteritis briefTitle: ICF in Takayasu Arteritis overallStatus: RECRUITING date: 2024-02-21 date: 2024-03-20 date: 2024-03-25 date: 2024-03-04 date: 2024-03-04 name: Pamukkale University class: OTHER briefSummary: The aim was to analyze the problem in patients with Takayasu Arteritis based on the International Classification of Functioning, Disability and Health.The sample of our study will consist of individuals between the ages of 18-65 who have been diagnosed with Takayasu Arteritis by rheumatologists and are followed by Pamukkale University Rheumatology Clinic. conditions: Takayasu Arteritis studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 15 type: ESTIMATED name: ICF measure: 6 open-ended questions sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Elif Gur Kabul status: RECRUITING city: Uşak country: Turkey name: Elif Gur Kabul, Assistant Professor role: CONTACT phone: 00.90.2582964282 phoneExt: 4282 email: elifgur1988@hotmail.com lat: 38.67351 lon: 29.4058 hasResults: False
nctId: NCT06289725 id: IRB-VN01002-23932 briefTitle: Impact of Hepatitis B Virus Genotype on Treatment Response in Children With Chronic Hepatitis B overallStatus: RECRUITING date: 2024-01-01 date: 2026-01-01 date: 2026-01-01 date: 2024-03-04 date: 2024-03-18 name: Ly Hoa Anh Minh class: OTHER briefSummary: The study aimed to evaluate the relationship between hepatitis B virus genotype and treatment response in children with chronic hepatitis B with specific treatment indications. This is a prospective cohort study, with a follow-up period of at least 12 months, conducted at Children's Hospital 1 and City Children's Hospital, Ho Chi Minh City, Vietnam. The patient's blood was taken to be tested for hepatitis B virus genotyping using Sanger sequencing at the Center for Molecular Biomedicine Ho Chi Minh City. The research hypothesis is that genotype is related to treatment response. conditions: Chronic Hepatitis b studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 84 type: ESTIMATED name: antiviral treatment measure: Serological response for HBeAg measure: Virological response measure: Biochemical response sex: ALL minimumAge: 2 Years maximumAge: 16 Years stdAges: CHILD facility: Children's Hospital 1 status: RECRUITING city: Ho Chi Minh City country: Vietnam name: Minh Hoa Anh Ly role: CONTACT phone: 0902352622 email: lhaminh.ncs.nhi23@ump.edu.vn lat: 10.82302 lon: 106.62965 facility: City Children's Hospital status: RECRUITING city: Ho Chi Minh City country: Vietnam name: Minh Hoa Anh Ly role: CONTACT email: lhaminh.ncs.nhi23@ump.edu.vn lat: 10.82302 lon: 106.62965 hasResults: False
nctId: NCT06289712 id: APHP231660 briefTitle: Evaluation of the Ablation of Hepatic Lesions by Electroporation acronym: EVALHEP overallStatus: RECRUITING date: 2023-11-23 date: 2025-05-23 date: 2025-05-23 date: 2024-03-04 date: 2024-03-04 name: Assistance Publique - Hôpitaux de Paris class: OTHER name: Inria Team MONC briefSummary: Irreversible electroporation is a curative treatment for cancerous liver lesions, performed on deep-seated tumors that are not eligible for surgical resection or percutaneous thermal ablation.
The EVALHEP project aims to develop criteria for evaluating the effectiveness of the treatment based on imaging, mathematical models, and numerical simulations to assist radiologists who perform these complex procedures. conditions: Liver Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 50 type: ESTIMATED measure: Correlate 3D numerical simulations of the IRE electric field with patient imaging follow-up measure: Calculation of the tumor coverage rate by the various electric field isolines at different relevant values (for example, three-dimensional isolines between 300 and 700V.cm-1 will be simulated numerically). measure: Correlation of recovery rate with treatment outcome and local recurrence during clinical follow-up measure: Identification and assessment of imaging biomarkers (radiomics-based) using numerical simulation and post-therapeutic imaging for treatment response evaluation. measure: Digital resolution of electrical potential and tissue conductivity values from test pulses at the start of the procedure. measure: Develop software solutions potentially usable in real-time and tailored for clinical use. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Service d'imagerie diagnostique et interventionnelle tri-site des HUPSSD status: RECRUITING city: Bobigny zip: 93009 country: France name: Olivier SUTTER role: CONTACT phone: 01 72 40 00 12 email: olivier.sutter@aphp.fr lat: 48.9 lon: 2.45 hasResults: False
nctId: NCT06289673 id: INITIALL id: NCI-2024-01659 type: REGISTRY domain: NCI Clinical Trial Registration Program briefTitle: Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2034-05 date: 2039-05 date: 2024-03-04 date: 2024-03-15 name: St. Jude Children's Research Hospital class: OTHER briefSummary: The goal of this study is to provide sufficient therapy during the time a patients' B-cell Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Leukemia (LLy) risk category is being determined. The term "risk" refers to the chance of the ALL or LLy coming back after treatment.
* To assess event free and overall survival data of patients enrolled on this study. conditions: Acute Lymphoblastic Leukemia conditions: Lymphoblastic Lymphoma conditions: Mixed Phenotype Acute Leukemia studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 850 type: ESTIMATED name: Dexamethasone name: Vincristine name: Daunorubicin name: Intrathecal triple therapy (methotrexate + hydrocortisone + cytarabine) name: Methotrexate name: Cytarabine measure: Sufficient phenotypic and/or genomic data necessary for therapeutic protocol assignment by Day 8 (completion of INITIALL therapy). measure: Complete data within the INITIALL database measure: Event Free Survival (EFS) measure: Overall Survival (OS) sex: ALL minimumAge: 1 Year maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: United States, Tennessee St. Jude Children's Research Hospital city: Memphis state: Tennessee zip: 38105 country: United States name: Seth E. Karol, MD role: CONTACT phone: 866-278-5833 email: referralinfo@stjude.org name: Seth E. Karol, MD role: PRINCIPAL_INVESTIGATOR lat: 35.14953 lon: -90.04898 hasResults: False
nctId: NCT06289647 id: 19-28923B id: 5UG1EY030833 type: NIH link: https://reporter.nih.gov/quickSearch/5UG1EY030833 briefTitle: Azithromycin Reduction to Reach Elimination of Trachoma B acronym: ARRET overallStatus: NOT_YET_RECRUITING date: 2024-02-28 date: 2029-08-31 date: 2029-08-31 date: 2024-03-04 date: 2024-03-04 name: University of California, San Francisco class: OTHER name: Institut National de Recherche Biomédicale. Kinshasa, République Démocratique du Congo name: National Eye Institute (NEI) briefSummary: The investigators propose a randomized controlled trial of discontinuation versus continuation of annual mass azithromycin distribution in hypoendemic communities of Maniema, DRC. The investigators will randomize communities with up to 20% Trachomatous Inflammation - Follicular (TF) prevalence following at least 5 years of mass azithromycin distribution to discontinuation or continuation of 3 additional years of annual mass azithromycin distribution. conditions: Trachoma studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Double (Investigator, Outcomes Assessor) whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 100000 type: ESTIMATED name: Azithromycin measure: Ocular chlamydia measured in a population-based sample of 0-9 year-old children measure: Infectious load of chlamydia among 0-9-year-old children infected with ocular chlamydia measure: Conjunctival inflammation sex: ALL minimumAge: 1 Month maximumAge: 9 Years stdAges: CHILD facility: University of California, San Francisco city: Kindu state: Maniema country: Congo, The Democratic Republic of the lat: -2.94373 lon: 25.92237 hasResults: False
nctId: NCT06289634 id: Pending briefTitle: The Influence of Sound on Stress, Anxiety, and Mood overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-04 date: 2024-04 date: 2024-03-04 date: 2024-03-04 name: Medgar Evers College, The City University of New York class: OTHER briefSummary: Multiple studies have highlighted music's ability to evoke diverse emotional states. Past research reveals that factors like musical elements, and the environment impact how people respond emotionally to music. For instance, faster tempos tend to heighten arousal, while minor key compositions evoke more arousal compared to major key compositions. In efforts to induce specific emotions post-stress, the research found that both pleasant and sad music aided stress recovery. Similarly, other researchers noted that positively rated music was more effective in reducing stress than negatively rated music, especially low arousal compositions over high arousal ones. Several studies focused on applying music to reduce stress and anxiety. In addition to man-made musical tones, the positive impact of natural surroundings on emotional state has been widely explored. A psycho-evolutionary viewpoint was offered, suggesting that humans have evolved in natural settings, making us inherently attuned to them physically and psychologically. A non-threatening natural environment, rich in aesthetically pleasing elements like visible escape routes, greenery, and water, tends to reduce stress and generate interest. In this study, the researchers are exploring how different sounds-man-made instrumental music versus natural sounds-affect stress, anxiety, and mood among the students of Medgar Evers College. Using an experimental approach, the researchers will assess pretest stress levels (via the perceived stress scale (PSS), anxiety (generalized anxiety disorder (GAD-7), and mood (four-dimensional mood scale (4DMS) among a sample of students. After randomly dividing them into two groups, each group will listen to one of the designated sounds (man-made music or nature sounds) for 30 minutes daily over 15 days. The researchers will then have them retake the stress, anxiety, and mood scales for post-test comparison. Statistical analysis (mixed ANOVA) will help to compare scores within and between groups. Ultimately, this study aims to determine the influence of tonal input on stress and anxiety levels among students, crucial given the significant stress they often experience. conditions: Healthy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 20 type: ESTIMATED name: Man-made sounds name: Natural sounds measure: Stress measure: Anxiety measure: Mood sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06289621 id: 2024P000420 id: K01TW012180 type: NIH link: https://reporter.nih.gov/quickSearch/K01TW012180 briefTitle: Brief Transdiagnostic Treatment for Anxiety Disorders and Post-traumatic Stress Disorder (PTSD) in South Africa overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-07-31 date: 2026-12-31 date: 2024-03-04 date: 2024-03-15 name: Massachusetts General Hospital class: OTHER name: University of Stellenbosch name: Fogarty International Center of the National Institute of Health name: Harvard Medical School (HMS and HSDM) briefSummary: The purpose of this study is to examine the use of a brief transdiagnostic treatment for anxiety disorders and (post-traumatic stress disorder (PTSD) in South Africa. The intervention will be delivered by non-specialist providers (e.g., nurses) in primary care clinics. The brief intervention group will be compared to an enhanced standard care control group. conditions: Anxiety Disorders conditions: Post-traumatic Stress Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: This is a Type 1 hybrid-effectiveness implementation trial. Study participants are randomized into the brief transdiagnostic treatment for anxiety disorders and post-traumatic stress disorder (PTSD) or an enhanced standard care control group. primaryPurpose: TREATMENT masking: NONE count: 60 type: ESTIMATED name: False Safety Behavioral Elimination Treatment (FSET) name: Enhanced Standard Care measure: Structured Clinical Interview for the DSM-5 (SCID-5) measure: Clinician-Administered PTSD Scale for the DSM-5 (CAPS) measure: Work Social Adjustment Scale (WSAS) measure: General Anxiety Disorder-7 (GAD-7) measure: Beck Anxiety Inventory (BAI) measure: Safety Aid Scale (SAS) measure: Post-traumatic Disorder Checklist (PCL-5 PTSD Checklist (PCL-5) measure: Patient Health Questionnaire - 9 (PHQ-9) measure: Beck Depression Inventory (BDI) measure: Anxiety Sensitivity Index -3 measure: Life Events Checklist (LEC) measure: Alcohol Use Disorders Identification Test (AUDIT) sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06289608 id: ID_2024 briefTitle: Bruxism and Underlying Psichological Factors overallStatus: RECRUITING date: 2023-02-01 date: 2024-03-01 date: 2024-03-01 date: 2024-03-04 date: 2024-03-04 name: University of Salamanca class: OTHER briefSummary: The aim of this study was o determine the relationship between self-reported bruxism (SB) and some psychological factors (i.e: Anxiety State-Trait; Stress Reactivity Index, Beck Depression Inventory). A consecutive sample of 101 patients that reported at least 2 of the 6 items of Bruxism self-reported index, were explored clinically for quantifying the number and severity of worn teeth, and also the severe and location of the muscular pain according to an standardized inventory. conditions: Bruxism conditions: Muscular Disorders, Atrophic conditions: Temporomandibular Joint Disorders studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 100 type: ESTIMATED name: No intervention measure: Depression Level measure: Stress Level measure: Anxiety sex: ALL minimumAge: 18 Years maximumAge: 100 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Clinica Odontológica de la Universidad de Salamanca status: RECRUITING city: Salamanca zip: 37007 country: Spain name: JAVIER MONTERO, DDS role: CONTACT phone: 619429971 email: javimont@usal.es lat: 40.96882 lon: -5.66388 hasResults: False