hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06366074 id: HUM00252120 briefTitle: Early-feasibility Study to Evaluate Usability and Safety of the Watch-Transcutaneous Electrical Acustimulation (TEA) Device overallStatus: NOT_YET_RECRUITING date: 2024-08 date: 2025-08 date: 2025-08 date: 2024-04-15 date: 2024-04-15 name: University of Michigan class: OTHER name: Transtimulation Research, Inc briefSummary: This project is being completed to test the usability and safety of the Watch-Transcutaneous Electrical Acustimulation (TEA) Device.
This is a pilot study that will lead to future projects for cancer patients that may experience chemotherapy-induced symptoms. conditions: Healthy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Prevalence of delayed Chemotherapy-induced nausea, emesis, and dyspeptic symptoms (CINEDS) is 75% in women vs 51% in men (60% to 40% ratio). Therefore, every effort will be made to recruit at least 60% female subjects into the clinical study. primaryPurpose: OTHER masking: NONE count: 20 type: ESTIMATED name: Watch-TEA group name: Tethered TEA device measure: Usability of the device for both groups day 3 measure: Number of adverse events related to the device noted on the safety questionnaire measure: Number of Transcutaneous Electrical Acustimulation (TEA)-related adverse events for both groups 3 days measure: Number of TEA-related adverse events for both groups 60 minutes at maximal tolerable level measure: Number of non-treatment TEA adverse events for both groups sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Michigan city: Ann Arbor state: Michigan zip: 48109 country: United States name: Colin Burnett role: CONTACT phone: 734-647-2806 email: bucolin@umich.edu name: Jiande Chen, PhD role: PRINCIPAL_INVESTIGATOR lat: 42.27756 lon: -83.74088 hasResults: False
nctId: NCT06366061 id: 2020-02868 briefTitle: A COMPARISON OF LEFT VENTRICULAR FUNCTION IN THE APICAL 4 CHAMBER AND SUBCOSTAL 4 CHAMBER TTE VIEWS IN THE PERIOPERATIVE SETTING overallStatus: RECRUITING date: 2022-05-14 date: 2024-07-01 date: 2024-12-01 date: 2024-04-15 date: 2024-04-15 name: Eckhard Mauermann class: OTHER briefSummary: This study aims to examine the correlation and agreement of regional and global measurements of ventricular function in the apical 4 chamber and subcostal 4 chamber view. Additionally, we will explore limitations of the technology and explore the effect of left lateral positioning. conditions: Cardiac Functional Disturbances During Surgery studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED measure: S'Tissue Doppler Index (TDI) AP4C supine vs. S'STE SC4C supine measure: Global longitudinal strain (GLS), AP4C supine vs. GLS, SC4C supine, i.e. clinical questions: can we use the SC4C for global markers of ventricular function? measure: Comparison of high Frame Rate (FR) vs. low FR of the following measures: [ i) S'STE AP4C supine, ii) GLS AP4C supine, iii) SR AP4C supine] measure: Comparison of the measured values in the cardiological gold standard (Left lateral decubitus (LLD)) vs. supine, for the following values [ i) S'TDI AP4C, ii) S'STE AP4C, iii) GLS] sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University Hospital Basel status: RECRUITING city: Basel state: Basel Stadt zip: 4000 country: Switzerland name: Michael Lampart, Prakt. med. role: CONTACT phone: +41764006180 email: michael.lampart@usb.ch lat: 47.55839 lon: 7.57327 hasResults: False
nctId: NCT06366048 id: EHBHKY2022-K-025 briefTitle: A Study on Relationship Between Resected Normal Liver Parenchymal Volume（RNLV）and Post-Hepatectomy Liver Failure (PHLF) acronym: RNLV overallStatus: ACTIVE_NOT_RECRUITING date: 2022-12-01 date: 2024-05-31 date: 2024-12-31 date: 2024-04-15 date: 2024-04-18 name: National Natural Science Foundation of China class: OTHER_GOV briefSummary: The post-hepatotectomy liver failure (PHLF) is still the most worrisome complication of hepatic resection. Surgeons have always been making efforts to preoperatively predict PHLF using kinds of techniques, scoring systems, and variables. The investigators of this study tried to create an individual predictive model based on the variable, resected normal parenchymal volume (RNLV), then assessing the performance and value of the model in clinical practice. conditions: Liver Failure studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: RETROSPECTIVE count: 1133 type: ACTUAL name: the different definitions of PHLF according to 50-50 criteria and ISGLS criteria measure: Probability of PHLF was predicted with our individual model based on RNLV. sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: The Third Affiliated Hospital of Naval Medical University city: Shanhai state: Shanghai zip: 201800 country: China hasResults: False
nctId: NCT06366035 id: NMRR ID-24-00924-HPO briefTitle: LoVE4MUM: Virtual Engagement for Preventing Postpartum Depression acronym: LoVE4MUM overallStatus: NOT_YET_RECRUITING date: 2024-04-22 date: 2024-06-03 date: 2024-10-01 date: 2024-04-15 date: 2024-04-16 name: National Institutes of Health, Ministry of Health Malaysia class: OTHER briefSummary: Postpartum depression is a serious concern affecting mothers and their infants, especially with limited traditional support. This pilot study evaluates the effectiveness of a novel mobile app called LoVE4MUM, developed based on Cognitive Behavioral Therapy and Psychoeducation principles, in preventing postpartum depression. The pilot trial involves 64 mothers randomly assigned to receive either standard care or standard care plus the LoVE4MUM. Primary outcome is improvement in depression, with secondary outcomes including mental health literacy and automatic negative thoughts. This research aims to provide initial evidence on the potential of mobile health tools to support maternal mental health, paving the way for future accessible and effective interventions. conditions: Postpartum Depression conditions: Maternal Behavior conditions: mHealth Intervention conditions: Mental Health Issue studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Single Blinded, Pilot Randomized Control Trial primaryPurpose: PREVENTION masking: SINGLE whoMasked: INVESTIGATOR count: 64 type: ESTIMATED name: LoVE4MUM mobile application measure: Postpartum Depression measure: Postpartum Mental Health Literacy measure: Automatic Negative Frequency sex: FEMALE minimumAge: 19 Years maximumAge: 50 Years stdAges: ADULT facility: Hospital Tengku Ampuan Rahimah city: Klang state: Selangor zip: 41586 country: Malaysia name: Noor Fadzleeyanna Mohd Yahaya, MOG role: CONTACT phone: 03-3375 7000 name: Noor Fadzleeyanna Mohd Yahaya, MOG role: PRINCIPAL_INVESTIGATOR name: Shalisah Sarip, PhD role: SUB_INVESTIGATOR name: Norfazilah Ahmad, PhD role: SUB_INVESTIGATOR lat: 3.03333 lon: 101.45 facility: Hospital Shah Alam city: Shah Alam state: Selangor zip: 40000 country: Malaysia name: Siti Sabrina Kamarudin role: CONTACT phone: 0355263000 phoneExt: 3305 email: saby721@gmail.com name: Siti Sabrina Kamarudin, MBBS role: PRINCIPAL_INVESTIGATOR name: NNurul Syuhaida Abdul Razak, MOG role: SUB_INVESTIGATOR name: Idayu Badilla Idris, PhD role: SUB_INVESTIGATOR lat: 3.08507 lon: 101.53281 hasResults: False
nctId: NCT06366022 id: Warsaw.06 briefTitle: Evaluation of the Treatment of Multiple Gingival Recession Using Modified Coronally Advanced Tunnel With Subepithelial Connective Tissue Graft Depending on the Positioning of the Graft overallStatus: RECRUITING date: 2023-05-30 date: 2024-05-30 date: 2024-05-30 date: 2024-04-15 date: 2024-04-15 name: Medical University of Warsaw class: OTHER briefSummary: Microsurgical coronally advanced tunnel procedures using subepithelial connective tissue grafts (sCTG) are predictable for healing of multiple adjacent type 1 and 2 gingival recessions (RT1 and RT2). In order to reduce patient morbidity and enhance periodontal wound healing with sCTG can be used. The aim of this study is to compare the results of the modified tunneling technique with subepithelial connective tissue graft in gingival recessions placed with the inner side towards the flap cover graft and the outer side towards the flap cover graft. conditions: Gingival Recession studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 20 type: ESTIMATED name: The tunnel technique for root coverage with CTG with inner side of the graft name: The tunnel technique for root coverage with CTG with outer side of the graft measure: Clinical attachment level (CAL) measure: Recession height (RH) measure: Recession width (RW) measure: Width of keratinized tissue (KTW) measure: Thickness of keratinized tissue (GT measure: Average recession coverage (ARC) measure: Complete recession coverage measure: Probing pocket depth (PPD) measure: Root coverage esthetic score (RES) measure: Post surgical pain and swelling measure: Patient's satisfaction with treatment sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Department of Periodontology and Oral Mucosa Diseases, Medical University of Warsaw status: RECRUITING city: Warsaw state: MAzowsze zip: 00-246 country: Poland name: Bartłomiej Górski, PhD role: CONTACT phone: 48225022099 lat: 52.22977 lon: 21.01178 hasResults: False
nctId: NCT06366009 id: Warsaw Study briefTitle: Assessment of Patients With Drug-resistant Temporal Lobe Epilepsy With EEG Extended With Intra-auricular Electrodes overallStatus: NOT_YET_RECRUITING date: 2024-04-08 date: 2024-07-31 date: 2024-07-31 date: 2024-04-15 date: 2024-04-15 name: Przemyslaw Kunert class: INDUSTRY name: NaoX Technologies name: Warsaw Medical University Clinical Center name: Departments and Clinics of Emergency Medicine of the Medical University of Gdańsk briefSummary: The study aims to evaluate the effectiveness of long-term video EEG monitoring using 10-20 electrodes extended with intra-auricular electrodes in locating the seizure onset zone and interictal epileptiform discharges (IEDs) in patients with temporal lobe epilepsy (TLE) and nontemporal lobe epilepsy (non-TLE). conditions: Epilepsy conditions: Focal Epilepsy conditions: Drug Resistant Epilepsy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30 type: ESTIMATED name: NaoX in-ear EEG system measure: determination of the starting point of focal temporal epileptic seizures measure: Identification of subgroups of epileptic patterns measure: Assessment of ease-of-use and comfort of use of the NAOX in-ear EEG system by patients and the EEG technician sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Kliniki Neurochirurgii CSK UCK WUM city: Warsaw country: Poland name: Przemysław Kunert, Prof. role: CONTACT name: Maja Kopytek-Beuzen, Dr. role: CONTACT lat: 52.22977 lon: 21.01178 hasResults: False
nctId: NCT06365996 id: Core set geriatric ICF briefTitle: Development and Validation of the Polish Geriatric Core Set. overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-12-15 date: 2025-12-15 date: 2024-04-15 date: 2024-04-15 name: University of Rzeszow class: OTHER briefSummary: Population ageing is a global problem. With ageing, involutionary changes and multimorbidity increase, leading to limitations in the performance of daily activities and disability. Proposed by the World Health Organisation (WHO), the geriatric core set is a set of categories of the International Classification of Functioning, Disability and Health (ICF) that allows for a comprehensive assessment of a person of geriatric age. In Poland, the geriatric core set has not yet been adapted and validated. Therefore, the aim of this study is the cultural adaptation and validation of the Polish version of the ICF-based categorical profile for the assessment of older people. conditions: Aging studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 800 type: ESTIMATED measure: ICF Geriatric core set measure: Sociodemographic data of the sample measure: Disability - WHODAS 2.0 v 36 item sex: ALL minimumAge: 60 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Rzeszow city: Rzeszów state: Podkarpacie zip: 35-959 country: Poland name: Agnieszka Sozańska, professor role: CONTACT phone: 530172857 email: asozanska@ur.edu.pl lat: 50.04132 lon: 21.99901 hasResults: False
nctId: NCT06365983 id: UFRGS-Cassio briefTitle: Comparison of Free Gingival Graft and Linear Incision for Connective Tissue overallStatus: RECRUITING date: 2023-04-28 date: 2025-04-28 date: 2026-04-28 date: 2024-04-15 date: 2024-04-15 name: Federal University of Rio Grande do Sul class: OTHER briefSummary: A randomized controlled non-inferiority trial will be conducted with 24 individuals aged 18 or older, who are periodontally healthy and require root coverage in bilateral multiple RT1-type recessions involving at least two teeth on each side of the mouth. The number of teeth to be covered must be equal on both sides to avoid imbalance in patient-centered comparisons.
INCLUSION CRITERIA Patients aged 18 or older requiring root coverage in bilateral multiple recessions involving at least two teeth on each side of the mouth will be included. The number of teeth to be covered must be equal on both sides to avoid imbalance in patient-centered comparisons. Recessions should be RT1 type according to the 2017 Workshop on the Classification of Periodontal Conditions and Diseases (Jepsen et al. 2018) and without non-carious cervical lesions.
Compare the two grafts in terms of clinical outcomes of root coverage; Compare the two grafts in terms of digital outcomes of root coverage obtained in scanning and tomography; Compare the two grafts in terms of patient-centered outcomes. conditions: Connective Tissue conditions: Gingiva conditions: Gingival Recession conditions: Humans studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A randomized controlled non-inferiority trial will be conducted with 24 individuals aged 18 or older, who are periodontally healthy and require root coverage in bilateral multiple RT1-type recessions involving at least two teeth on each side of the mouth. The number of teeth to be covered must be equal on both sides to avoid imbalance in patient-centered comparisons. primaryPurpose: TREATMENT masking: SINGLE maskingDescription: All sample randomization procedures will be carried out by a researcher not involved in treatments and clinical examinations. An external researcher not affiliated with the study will be responsible for maintaining participant allocation confidentiality. Sides will be identified by numbers stored in opaque, sealed envelopes with the randomization sequence. Outcome assessors will be blinded to the experimental group to which participants belong. whoMasked: OUTCOMES_ASSESSOR count: 24 type: ESTIMATED name: Connective Tissue with Free Gingival Graft name: Connective Tissue with Linear Incision measure: Percentage of root coverage measure: Recession depth sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Alex Nogueira Haas status: RECRUITING city: Porto Alegre state: RS zip: 95780000 country: Brazil name: Cássio Cardona Orth role: CONTACT phone: 11999791876 email: cassio.orth@gmail.com lat: -30.03306 lon: -51.23 hasResults: False
nctId: NCT06365970 id: HCC 23-056 briefTitle: Niraparib and Dostarlimab for Patients With MMR-D/MSI-H Colorectal Cancers overallStatus: NOT_YET_RECRUITING date: 2024-05-31 date: 2026-05-31 date: 2027-05-31 date: 2024-04-15 date: 2024-04-15 name: Ibrahim Halil Sahin class: OTHER name: GlaxoSmithKline briefSummary: The second line of therapy for patients with MSI-H CRC who experience disease progression on anti-PD1 based therapies is not well defined and there is an unmet need for research for patients with anti-PD1 refractory MSI-H CRC. This study will examine the combination of niraparib and dostarlimab for a synergistic antitumor effect for patients with MSI-H CRC. conditions: MMR-D/MSI-H Colorectal Cancers studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 20 type: ESTIMATED name: Niraparib name: Dostarlimab measure: Objective response rate (ORR) measure: Adverse Events Related to Treatment measure: Progression-free Survival (PFS) measure: Duration of Response (DoR) measure: Overall Survival (OS) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: UPMC Hillman Cancer Center city: Pittsburgh state: Pennsylvania zip: 15232 country: United States name: Debra Diecks, MSN role: CONTACT phone: 412-623-8364 email: diecksda@upmc.edu name: Ibrahim Sahin, MD role: PRINCIPAL_INVESTIGATOR lat: 40.44062 lon: -79.99589 hasResults: False
nctId: NCT06365957 id: BSERE24-APP001-FED briefTitle: Acute Effects of Exercise Combined With Ketone Ester Supplement overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-03 date: 2025-04 date: 2024-04-15 date: 2024-04-22 name: University of Macau class: OTHER briefSummary: To examine the acute changes in cardiometabolic and neurocognitive outcomes in response to exercise combined with ketone ester supplement in overweight/obese adults. conditions: Overweight and Obesity conditions: Cognitive Change conditions: Ketoses, Metabolic studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: SUPPORTIVE_CARE masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 20 type: ESTIMATED name: Ketone monoester supplementation name: High-intensity interval exercise name: Moderate-intensity continuous exercise name: Placebo measure: Maximal Oxygen Uptake measure: Systolic Blood Pressure measure: Diastolic Blood Pressure measure: Concentration of Blood Lipid measure: Concentration of Blood Glucose measure: Concentration of Blood Beta-Hydroxybutyrate measure: Concentration of Blood Lactic Acid measure: Concentration of Blood Insulin measure: Reaction Time of Stroop Task measure: Accuracy of Stroop Task measure: Reaction Time of N-back Task measure: Accuracy of N-back Task measure: Cerebral Hemoglobin Concentration measure: Arousal Level sex: ALL minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT hasResults: False
nctId: NCT06365944 id: CHUBX 2023/73 briefTitle: Concussion in French Non-professional Handball League : Efficiency of a Concussion Protocol, the White Card Process acronym: PRECCOCE overallStatus: RECRUITING date: 2024-04-20 date: 2026-04-20 date: 2026-04-20 date: 2024-04-15 date: 2024-04-24 name: University Hospital, Bordeaux class: OTHER briefSummary: Sport related concussion is a major issue for many contact sports, such as Rugby, Football, Hockey and Handball. As a response, some federations like World Rugby set up a concussion protocol, that starts with the referee having the responsibility to issue a blue card when suspecting a concussed player and thus have him off the field for medical examination. The French handball federation (FFHB) as well as its concussion protocol called "Protocole carton blanc", in this study we aim to describe the efficiency of this protocol. conditions: Brain Concussion conditions: Cerebral Concussion studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 3000 type: ESTIMATED measure: Proportion, as a percentage, of participant declaring no medical care while being estimated at risk of having a concussion (assessed by answers to the questionnaire) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Bordeaux University Hospital status: RECRUITING city: Bordeaux country: France name: Quentin LHUAIRE role: CONTACT lat: 44.84044 lon: -0.5805 hasResults: False
nctId: NCT06365931 id: 160224 briefTitle: Physiological and Functional Effects of Percutaneous Neuromodulation vs Transcutaneous Neuromodulation overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-16 date: 2024-02-16 date: 2024-04-30 date: 2024-04-15 date: 2024-04-15 name: University of Extremadura class: OTHER briefSummary: INTRODUCTION: Clubfoot, drop foot or clubfoot, is a disorder that prevents reaching 100º of dorsiflexion actively. Its etiology is varied, and may be due to congenital problems, direct alteration of the bone structure, spasticity or shortening of the posterior musculature (triceps suralis), a neurological factor or a combination of several. Thus, we can differentiate between congenital clubfoot and acquired clubfoot. Stroke is one of the main causes of acquired clubfoot, which is due to paralysis of the dorsiflexor musculature and/or spasticity of the plantar flexor musculature. Electrical stimulation is able to increase muscle activation by depolarization of the motor plate and modulation of nerve conduction. This can be done transcutaneously, through surface electrodes or percutaneously through needles, so neuromodulation is presented as a tool applicable to the pathology of the equine foot, if we take into account the increased activation of the dorsiflexors of the foot.
METHODOLOGY: a clinical trial with randomized probabilistic assignment in four groups is proposed: G1 (percutaneous neuromodulation): patients will receive a needle circuit approaching the deep peroneal nerve in an ultrasound-guided manner. They will receive a 20-30Hz symmetrical biphasic current; G2 (transcutaneous neuromodulation): patients will have a superficial electrode circuit placed over the belly of the tibialis anterior muscle. They will receive a symmetrical biphasic current of 20-30Hz; G3 (placebo-percutaneous group): in which the patients will receive the neuromodulation circuit with needles at 0 intensity; G2 (placebo-transcutaneous group): the patients will receive the electrodes at 0 intensity over the belly of the tibialis anterior muscle.
The variables to be analyzed are: anthropometric variables (age, weight, height, BMI), muscle oxygenation (SatO2, O2Hb, HHb and THb), muscle strength of the foot dorsiflexors measured with dynamometer, muscle activation by surface electromyography, active and passive joint balance with goniometry or inclinometer, assessment of gait and balance, assessment of load distribution by static and dynamic pressure platform, spasticity and questionnaire on quality of life and functionality. The acute effects after one intervention session (pre-post intervention of one session) and the effects after a 10-session program will be analyzed. conditions: Stroke/Brain Attack studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 30 type: ACTUAL name: Percutaneous neuromodulation name: Transcutaneous neuromodulation name: Placebo-percutaneous name: Placebo-transcutaneous name: Percutaneous neuromodulation or Transcutaneous neuromodulation (optional) measure: Muscle activity measure: Displacement of the center of pressures (CoP) measure: Articular amplitude measure: Balance measure: Balance measure: Gait measure: Tissue oxygen in muscle measure: Muscular strength measure: Functionality measure: quality of life index measure: Spasticity sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mª Dolores Apolo Arenas city: Badajoz country: Spain lat: 38.87789 lon: -6.97061 hasResults: False