nctId: NCT06323538 id: 01 briefTitle: Cohort Study on Plant-based Diets (COPLANT Study) acronym: COPLANT overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2027-03-31 date: 2047-03-31 date: 2024-03-21 date: 2024-03-22 name: German Federal Institute for Risk Assessment class: OTHER name: Max Rubner-Institut name: University of Bonn name: Research Institute for Plant-Based Nutrition name: University of Jena name: University of Regensburg name: Heidelberg University name: University of Vienna briefSummary: The Cohort on Plant-based Diets (COPLANT) study is a multi-centre cohort study that starts baseline recruitment from 2024 to 2027 with approximately 6,000 participants in Germany and Austria. The COPLANT study focuses on vegan (no animal products), vegetarian (no meat and fish, but dairy products and eggs), pescetarian (no meat, but fish) and omnivorous (mixed diet including all possible animal products) diets. The aim of the COPLANT study is to gain new insights on health benefits and risks as well as social, ecological and economic effects of different plant-based diets in comparison to a mixed diet. In addition to a detailed dietary survey using an app adapted to the needs of this study, the baseline examination includes measurements of body composition, bone health, cardiovascular risk factors, diabetes risk, contaminants and lifestyle. For the basic laboratory program, fasting blood, 24-hour urine collection and a stool sample are taken from all study participants. Furthermore, specific aspects of dietary behavior, physical activity and other lifestyle factors are collected via questionnaires. Follow-up studies are planned at intervals of 5, 10 and 20 years after the baseline visit. conditions: Dietary Exposure conditions: Diabetes Mellitus, Type 2 conditions: Cardiovascular Diseases conditions: Bone Loss conditions: Sustainability conditions: Exposure conditions: Obesity conditions: Vitamin Deficiency conditions: Mineral Deficiency studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 6000 type: ESTIMATED measure: Incidence of diabetes type 2 measure: Incidence of cardiovascular diseases measure: Incidence of cancer measure: Vitamin B12 measure: Holo-transcobalamine measure: Homocysteine measure: Methylmalonic acid measure: Vitamin B1 status measure: Vitamin B2 status measure: Vitamin B6 status measure: Vitamin C status measure: Vitamin D status measure: Vitamin E status measure: Iron measure: Ferritin measure: Transferrin measure: Zinc status measure: Selenium status measure: Iodine status measure: Blood pressure measure: Blood lipids measure: Fasting insulin measure: Fasting glucose measure: Glycated hemoglobin (HbA1c) measure: C-peptide measure: Osteocalcin measure: Ostase measure: Parathormone measure: N-terminal propeptide of type I procollagen (PINP) measure: C-terminal telopeptide of type I collagen (CTX) measure: Creatinine measure: Uric acid measure: Cytstatin C measure: Thyroid stimulating hormone (TSH) measure: Free triiodothyronine (fT3) measure: Free thyroxine (fT4) measure: Body fat measure: Skeletal muscle mass measure: Total Body Water measure: Energy intake measure: Nutrient intake measure: Intake of dietary supplements measure: Intake of medication measure: Heavy metals measure: Halogenated, polycyclic aromatic hydrocarbons (dioxins) measure: Mycotoxins measure: Per- and polyfluoroalkyl substances (PFAS) measure: Microbiome sex: ALL minimumAge: 18 Years maximumAge: 69 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University Vienna city: Vienna zip: 1090 country: Austria lat: 48.20849 lon: 16.37208 facility: Max Rubner-Institut city: Karlsruhe state: Baden-Württemberg zip: 76131 country: Germany name: Benedikt Merz, PhD role: CONTACT email: benedikt.merz@mri.bund.de lat: 49.00937 lon: 8.40444 facility: Friedrich-Schiller University city: Jena state: Thuringia zip: 07743 country: Germany name: Christine Dawczynski, PhD role: CONTACT phone: +49 3641 949656 email: christine.dawczynski@uni-jena.de lat: 50.92878 lon: 11.5899 facility: The German Federal Institut for Risk Assessment city: Berlin zip: 10589 country: Germany name: Cornelia Weikert, Prof role: CONTACT phone: +49 30 1841255000 email: Cornelia.Weikert@bfr.bund.de lat: 52.52437 lon: 13.41053 facility: University Bonn city: Bonn country: Germany name: Ute Nöthlings, Prof role: CONTACT email: noethlings@uni-bonn.de lat: 50.73438 lon: 7.09549 facility: Research Institute for Plant-Based Nutrition, Gießen city: Gießen zip: 35444 country: Germany name: Markus Keller, PhD role: CONTACT email: keller@ifpe-giessen.de lat: 50.58727 lon: 8.67554 facility: University Heidelberg city: Heidelberg zip: 69120 country: Germany name: Ina Danquah role: CONTACT email: ina.danquah@uni-heidelberg.de lat: 49.40768 lon: 8.69079 facility: University Regensburg city: Regensburg zip: 93053 country: Germany name: Michael Leitzmann, Prof role: CONTACT email: Michael.Leitzmann@klinik.uni-regensburg.de name: Beate Fischer role: CONTACT email: Beate.Fischer@klinik.uni-regensburg.de lat: 49.01513 lon: 12.10161 typeAbbrev: Prot hasProtocol: True hasSap: False hasIcf: False label: Study Protocol date: 2023-11-20 uploadDate: 2024-02-23T09:43 filename: Prot_000.pdf size: 1528917 hasResults: False