hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06276699 id: FAHS briefTitle: Efficacy of a Combination of Conservative Treatments Compared to Isometric Exercise on Clinical Outcomes in Patients With Cervical Radiculopathy overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-05 date: 2024-06 date: 2024-02-26 date: 2024-04-16 name: University of Peradeniya class: OTHER briefSummary: This intervention study is to evaluate the efficacy of a combination of conservative treatments compared to isometric exercise on clinical outcomes in patients with cervical radiculopathy. It is a randomized, parallel, 2-arm superiority trial study. The study will be conducted at the District General Hospital in Trincomalee, where patients with cervical radiculopathy seek medical care. Patients who refer to the Department of Physical Medicine (DPM) from the Out Patients Department (OPD), orthopedic clinic and surgical clinic with a diagnosis of cervical radiculopathy or neck and arm pain (symptoms extending distal to the shoulder) will be eligible for recruitment. The study details will be explained to the subjects in the language that they best understand. Written informed consent will be obtained from the individuals who express their willingness to participate in the study, and they will sign the informed consent document accordingly. conditions: Cervical Radiculopathy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 46 type: ESTIMATED name: 1.Isometric exercise 2.combined conservative treatment measure: Difference in pain intensity measured by Visual Analogue Scale (VAS) between combination of treatments and isometric exercises at 6-weeks post-baseline. measure: Difference in cervical ROM measured by Goniometry between combination of treatments and isometric exercises at 6-weeks post-baseline. measure: Difference in functional disability measured by Neck Disability Index between combination of treatments and isometric exercises at 6-weeks post-baseline sex: ALL minimumAge: 35 Years maximumAge: 60 Years stdAges: ADULT hasResults: False
nctId: NCT06276686 id: RS211 - 332296 briefTitle: Exercise for Improving Long-course Chemoradiotherapy Efficacy in People With Locally Advanced Rectal Cancer overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-01 date: 2026-02 date: 2024-02-26 date: 2024-04-24 name: University of Hull class: OTHER name: Hull University Teaching Hospitals NHS Trust briefSummary: This is a single arm feasibility study of exercise for improving long- course neoadjuvant chemoradiotherapy (NACRT) efficacy in people diagnosed with locally advanced rectal cancer. The study aims to recruit up to 30 patients from the Queen's Centre for Oncology and Haematology of Castle Hill Hospital, Cottingham, diagnosed with locally advanced rectal cancer. Consenting patients will be provided with an 11-week course of structured aerobic exercises and resistance training in the periods before, during and after their chemoradiotherapy treatment. The patients will be followed up for 6 months post long course neoadjuvant chemoradiotherapy (NACRT), with a total of 3 assessment periods. conditions: Locally Advanced Rectal Carcinoma studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: BASIC_SCIENCE masking: NONE count: 30 type: ESTIMATED name: Supervised Vigorous intensity aerobic interval exercise measure: Recruitment rate measure: Attendance rate measure: withdrawal rate measure: Serum Carcinoembryonic antigen levels measure: Quality of life measure: Quality of life measure: Physical activity levels sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06276673 id: 301 briefTitle: The Influences of Single Chamber vs. Multi-chamber Blood Flow Restriction Cuffs overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-13 date: 2024-11-10 date: 2024-12-10 date: 2024-02-26 date: 2024-02-26 name: Salisbury University class: OTHER briefSummary: The purpose of this study is to investigate the use of single (SC) and multi-chamber (MC) blood flow restriction (BFR) cuff exercise on indices of arterial stiffness, muscle morphology, and participant perception. conditions: Blood Vessel Disease conditions: Muscle Edema studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Participants will undergo three treatment sessions (control (no BFR), SC BFR, and MC BFR) in a randomized order separated by one week. primaryPurpose: BASIC_SCIENCE masking: NONE maskingDescription: Unable to blind due to differences in cuff size and appearance. count: 35 type: ESTIMATED name: Delfi measure: Arterial Stiffness measure: Muscle Morphology sex: ALL minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: Salisbury University city: Salisbury state: Maryland zip: 21801 country: United States lat: 38.36067 lon: -75.59937 hasResults: False
nctId: NCT06276660 id: STUDY23070079 briefTitle: Post-Concussion Differences Between Buffalo Concussion Treadmill Test (BCTT) and Modified Dynamic Exertion (mEXiT) Test overallStatus: RECRUITING date: 2024-03-05 date: 2024-09 date: 2024-12-31 date: 2024-02-26 date: 2024-03-06 name: University of Pittsburgh class: OTHER briefSummary: This study aims to compare symptom provocation, physiologic response, and rate of perceived (RPE) between the Buffalo Concussion Treadmill Test (BCTT) and a Modified Dynamic Exertion (mEXiT) test after sport related concussion in adolescents aged 14-17. Participants will be enrolled at their initial concussion clinical visit within 14 days of their injury, and randomly assigned to either the BCTT or mEXiT group. Participants will complete a single visit. conditions: Mild Traumatic Brain Injury studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 60 type: ESTIMATED name: BCTT name: Dynamic ExIT measure: Physiological response to dynamic or aerobic test (HEART RATE) measure: Post Concussion Symptom Scale measure: Patient Health Questionnaire (PHQ-9) measure: Generalized Anxiety Disorder (GAD-7) measure: Vestibular Ocular Motor Screening (VOMS) measure: Clinical Profiles Screening (CP-Screen) measure: Blood Pressure sex: ALL minimumAge: 14 Years maximumAge: 17 Years stdAges: CHILD facility: UPMC/Univ of Pgh Sports Medicine Concussion Research Program status: RECRUITING city: Pittsburgh state: Pennsylvania zip: 15203 country: United States name: Cynthia Holland, MPH role: CONTACT phone: 412-904-1298 email: clh197@pitt.edu lat: 40.44062 lon: -79.99589 hasResults: False
nctId: NCT06276647 id: 850584 id: R01MD016029 type: NIH link: https://reporter.nih.gov/quickSearch/R01MD016029 briefTitle: Improving Health Outcomes and Equity by Targeting Postpartum Mothers at Highest Risk acronym: HOME overallStatus: RECRUITING date: 2024-02-20 date: 2025-02-15 date: 2025-05-31 date: 2024-02-26 date: 2024-03-01 name: University of Pennsylvania class: OTHER name: National Institutes of Health (NIH) name: Columbia University name: National Institute on Minority Health and Health Disparities (NIMHD) briefSummary: The goal of this educational clinical trial is to identify Black women most at risk for poor outcomes following delivery, the problems they experience, and to create a system to improve quality of postpartum care for high-risk women. The main question\[s\] it aims to answer are:
Participants will be put into the study group or control group. The study group will receive a pamphlet postpartum with helpful information as well as a patient navigator who the participants will be able to reach out to their first 30 days postpartum. conditions: Maternal Behavior conditions: Postpartum Depression studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 214 type: ESTIMATED name: HOME measure: Emergency Department (ED) Visits and Readmissions measure: Ability to Obtain Needed Services measure: Depressive Symptoms measure: Depressive Symptoms sex: FEMALE minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: Hospital of the University of Pennsylvania status: RECRUITING city: Philadelphia state: Pennsylvania zip: 19104 country: United States name: Elizabeth Howell, MD MPP role: CONTACT email: elizabeth.howell1@pennmedicine.upenn.edu name: Micki Burdick, PhD role: CONTACT email: micki.burdick@pennmedicine.upenn.edu name: Elizabeth Howell, MD MPP role: PRINCIPAL_INVESTIGATOR lat: 39.95233 lon: -75.16379 hasResults: False
nctId: NCT06276634 id: STU00219535 id: R21HD108587 type: NIH link: https://reporter.nih.gov/quickSearch/R21HD108587 briefTitle: Intermittent Hypoxia in Persons With Multiple Sclerosis overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-01 date: 2027-01 date: 2024-02-26 date: 2024-04-09 name: Shirley Ryan AbilityLab class: OTHER name: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) name: Northwestern University briefSummary: This study aims to understand the mechanisms of a novel intervention involving breathing short durations of low levels of oxygen for persons with multiple sclerosis (MS). This intervention with low levels of oxygen is called Acute Intermittent Hypoxia (AIH), the levels of oxygen experienced are similar to breathing the air on a tall mountain, for less than 1 minute at a time. Previous studies have shown that AIH is a safe and effective way to increase strength in persons with MS. Here the investigators aim to look at brain activation and ankle strength before and after AIH to gain a better understanding of how the AIH may improve strength in those persons with MS. conditions: Multiple Sclerosis conditions: Multiple Sclerosis-Relapsing-Remitting conditions: Multiple Sclerosis, Secondary Progressive studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Randomized, double-blind, placebo-controlled, cross-over, repeated measures study design primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 21 type: ESTIMATED name: Acute Intermittent Hypoxia name: Sham-Acute Intermittent Hypoxia measure: Ankle Plantarflexion Strength measure: Task fMRI measure: Timed 25 Feet Walk test measure: Six-Minute Walk test measure: Stride length measure: 12-Item Multiple Sclerosis walk scale (MSWS-12) measure: Resting-State fMRI sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Shirley Ryan AbilityLab city: Chicago state: Illinois zip: 60611 country: United States name: Alexander Barry, MS, CCRC role: CONTACT phone: 312-238-1435 email: abarry@sralab.org name: Milap Sandhu, PT, PhD role: PRINCIPAL_INVESTIGATOR name: Molly Bright, D.Phil. role: SUB_INVESTIGATOR lat: 41.85003 lon: -87.65005 hasResults: False
nctId: NCT06276621 id: STUDY00003564 briefTitle: Family Bridge Program overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-05 date: 2026-05 date: 2024-02-26 date: 2024-02-26 name: Seattle Children's Hospital class: OTHER name: Children's Hospital of Philadelphia briefSummary: Pediatric healthcare inequities in the United States (US) remain persistent and pervasive. Suboptimal patient-provider communication plays an important role in creating and maintaining disparate outcomes; this is compounded by mismatches between a family's skills and resources and demands imposed by the complexity of the health system (such as health literacy and system navigation). Few interventions exist to address inequities related to communication and system navigation in the inpatient setting; given the established links between these inequities and disparate clinical outcomes, such interventions are needed. To address this gap, the study team collaborated with parents/caregivers, staff, and providers to develop and pilot-test a novel program to improve navigation ability, communication, and hospital-to-home transition for a diverse population of children and their families, The Family Bridge Program (FBP).
The FBP combines principles of effective patient navigation and communication coaching interventions into a brief and targeted inpatient program. It is designed for a broad population of low-income children of color, is not disease-specific, is not limited to English proficient families, and is less time-intensive than traditional navigation, to enable provision of support to more families. The FBP, delivered in-person by a trained lay navigator, includes: (1) hospital orientation; (2) unmet social needs screening (e.g., food insecurity); (3) parent communication and cultural preference assessment, relayed to the medical team; (4) communication coaching for parents; (5) emotional support; (6) assistance with care coordination and logistics; and (7) a phone call 2 days post-discharge. Program elements are flexibly delivered based on parent need and interest.
In pilot testing, the program was feasible to deliver, acceptable to parents and providers, and significantly improved parent-reported system navigation ability. The current R01 proposes a two-site randomized controlled trial (RCT) of the effectiveness of FBP among 728 families of low-income children of color. Enrolled families will be randomized 1:1 (stratified by site and language) to FBP or usual care plus written resources. The specific aims of this clinical trial are to (1) Test the effect of the FBP on parent-reported system navigation ability, quality of hospital-to-home transition, diagnosis comprehension, observed communication quality, perceived stress and revisits for families of low-income children of color; (2) Examine whether changes in parent-reported barriers and needs mediate program effects; and (3) Identify subgroups of parents among whom the FBP is more effective. The proposed RCT will use a rigorous design to test a feasible, innovative program to address a critical national problem. If effective, the Family Bridge Program would provide a scalable model for improving health care experiences and outcomes for families of low-income children of color, including those who prefer a language other than English for their medical care. conditions: Healthcare Inequities conditions: General Pediatric Medical Conditions conditions: Healthcare System Navigation conditions: Patient-provider Communication studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 728 type: ESTIMATED name: Family Bridge Program name: Care as usual - resources only measure: System Navigation Ability measure: Pediatric Transition Experience Measure (P-TEM) measure: Diagnosis Comprehension measure: Perceived Stress Scale measure: Observed Communication: utterances in which team offers information measure: Observed Communication: utterances in which team offers supportive talk measure: Observed Communication: utterances in which parent asks questions measure: Observed Communication: utterances in which parent responds assertively measure: Observed Communication: parent talk-time measure: Observed Communication: global partnership rating measure: 30-day readmissions sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06276608 id: PED_Fe_def briefTitle: Iron Deficiency in Pediatric Heart Surgery overallStatus: RECRUITING date: 2024-02-23 date: 2024-04-20 date: 2024-06-30 date: 2024-02-26 date: 2024-02-28 name: Queen Fabiola Children's University Hospital class: OTHER briefSummary: The prevalence of iron deficiency in pediatric cardiac surgery patients is not very well known. Iron deficiency can lead to anemia, higher transfusion rates and possibly higher complication rates. In this retrospective study, the iron status of all patients undergoing pediatric cardiac surgery at our institution between January 2019 and december 2023 will be analyzed. Together with iron status, transfusion requirements as well as complications will be recorded. Iron status will be reported with descriptive statistics, patients with or without iron deficiency will be compared using non-parametric tests. conditions: Iron Deficiencies conditions: Iron Deficiency Anemia conditions: Cardiac Surgical Procedures conditions: Congenital Heart Disease in Children studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 300 type: ESTIMATED name: Iron status measure: Prevalence of preoperative iron deficiency (%) measure: Complications sex: ALL maximumAge: 16 Years stdAges: CHILD facility: H.U.B - Hôpital Universitaire des Enfants Reine Fabiola status: RECRUITING city: Brussels zip: 1020 country: Belgium name: Denis Schmartz, MD role: CONTACT phone: +3225553919 email: denis.schmartz@hubruxelles.be lat: 50.85045 lon: 4.34878 hasResults: False
nctId: NCT06276595 id: IRB00009466 briefTitle: Telling Our Daughters Our Story acronym: TODOS overallStatus: ACTIVE_NOT_RECRUITING date: 2019-03-30 date: 2022-03-22 date: 2024-07-30 date: 2024-02-26 date: 2024-02-26 name: Johns Hopkins Bloomberg School of Public Health class: OTHER name: White Mountain Apache Tribe name: Native American Research Centers for Health briefSummary: The objective of this research study is to evaluate a culturally grounded program among American Indian (AI) female children and the children's female caregivers. This project will evaluate the impact of "Nowhi Isdza bit Nadagoldi: Telling Our Daughters Our Story (henceforth referred to as TODOS) on associated risk and protective factors for early substance use and sexual debut through a randomized controlled trial on the White Mountain Apache (WMA) reservation. The investigators will examine whether the TODOS program effectively reduces risk factors and improves protective factors associated with early substance use and sexual debut, with long term goals of reducing teen pregnancy and teen substance use. conditions: Substance Use conditions: Sexual Behavior studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 183 type: ACTUAL name: Nowhi Isdza bit Nadagoldi: Telling Our Daughters Our Story (TODOS) name: Control condition - 3 Monthly Group Activities in the Community measure: Change in child cultural knowledge score on knowledge assessment measure: Change in average score on risky behaviors assessment measure: Change in child reproductive health knowledge via a reproductive health knowledge questionnaire sex: FEMALE minimumAge: 8 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: White Mountain Apache Center for Indigenous Health city: Whiteriver state: Arizona zip: 85941 country: United States lat: 33.83699 lon: -109.96427 hasResults: False
nctId: NCT06276582 id: 519379-2 briefTitle: Screening for Neonatal Jaundice With a Mobile Health Device: a Validation Study in Oaxaca, Mexico. overallStatus: RECRUITING date: 2023-01-17 date: 2024-05-31 date: 2024-05-31 date: 2024-02-26 date: 2024-02-26 name: Norwegian University of Science and Technology class: OTHER name: Picterus AS name: Instituto Mexicano del Seguro Social briefSummary: The performance and accuracy of the smartphone application (app) Picterus Jaundice Pro (PicterusJP) will be validated by a cross-sectional study conducted in low resource settings in Mexico. Physics-based and machine learning-based models will be used to analyze the images obtained with the app and its performance will be compared. conditions: Jaundice, Neonatal studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: SCREENING masking: NONE count: 150 type: ESTIMATED name: Screening for neonatal jaundice with a mobile health device measure: Enable high qualitative estimation of bilirubin levels in the blood of Mexican newborns using Picterus JP measure: Correlation between bilirubin measurements with Picterus JP and total serum bilirubin measure: Accuracy of Picterus JP to screen for neonatal jaundice sex: ALL minimumAge: 1 Day maximumAge: 14 Days stdAges: CHILD facility: Hospital General de Zona 1 status: RECRUITING city: Oaxaca zip: 68040 country: Mexico name: Rey Manuel Silva Mendez role: CONTACT phone: +529511283520 email: reymsilvam@gmail.com lat: 17.06542 lon: -96.72365 hasResults: False
nctId: NCT06276569 id: 2023-LCYJ-MS-26 briefTitle: Efficacy and Safety of Sivelestat in Preventing Postoperative Acute Respiratory Distress Syndrome After Cardiac Surgery :a Single Centre Random Control Trial. overallStatus: NOT_YET_RECRUITING date: 2024-02-18 date: 2026-06-30 date: 2026-12-31 date: 2024-02-26 date: 2024-02-28 name: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School class: OTHER briefSummary: The aim of this study is to assess the effectiveness and safety of sivelestat sodium in preventing acute respiratory distress syndrome (ARDS) following cardiac surgery, with the objective of providing evidence-based support for its clinical application. conditions: Cardiac Disease studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 384 type: ESTIMATED name: Sivelestat name: placebo measure: Oxygenation index measure: Inflammatory index measure: Myocardial injury marker measure: Acute physiology and chronic health evaluation(APACHE II) socre measure: Murray socre measure: ICU time measure: In-hospital time measure: 30-day all-cause mortality measure: 90-day all-cause mortality sex: ALL minimumAge: 50 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06276543 id: C-BSEAL-002 briefTitle: Bactiseal Catheter Safety Registry Study overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2026-07-31 date: 2026-12-31 date: 2024-02-26 date: 2024-04-19 name: Integra LifeSciences Corporation class: INDUSTRY briefSummary: Research Purpose:
5. Relevant examinations in case of postoperative infection, including bacterial culture and drug resistance testing (if done) conditions: Hydrocephalus studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 200 type: ESTIMATED name: antibiotic-impregnated catheter measure: Infection outcome measure: Safety outcome sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Beijing Children's Hospital, Capital Medical University city: Beijing state: Beijing zip: 100045 country: China name: Hailang Sun, MD role: CONTACT phone: 0086-10-59616408 email: et2007yy@163.com lat: 39.9075 lon: 116.39723 facility: Xuanwu Hospital, Capital Medical University city: Beijing state: Beijing zip: 100053 country: China name: Ning Wang, MD role: CONTACT phone: 010-83198899 lat: 39.9075 lon: 116.39723 facility: Beijing Hospital city: Beijing state: Beijing zip: 100730 country: China name: Cheng Sha, MD role: CONTACT phone: 0086-10-85132266 email: bjshacheng@163.com lat: 39.9075 lon: 116.39723 facility: Guangzhou Women and Children Medical Center city: Guangzhou state: Guangdong zip: 510623 country: China name: Fangcheng Li, MD role: CONTACT phone: 020-81886332 lat: 23.11667 lon: 113.25 facility: Guangdong Province People Hospital city: Guangzhou state: Guangdong zip: 519041 country: China name: Feng Wang, MD role: CONTACT phone: 0086 20 83827812 lat: 23.11667 lon: 113.25 facility: Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology city: Wuhan state: Hubei zip: 430030 country: China name: Ting Lei, MD role: CONTACT phone: 0086 27 83662688 lat: 30.58333 lon: 114.26667 facility: Shanghai Children's Medical Center affiliated to Shanghai Jiaotong University School of Medicine city: Shanghai state: Shanghai zip: 200127 country: China name: Nan Bao, MD role: CONTACT phone: 0086-21-38626161 email: baonan@scmc.com.cn lat: 31.22222 lon: 121.45806 facility: West China Hospital of Sichuan University city: Chengdu state: Sichuan zip: 610041 country: China name: Jianguo Xu, MD role: CONTACT phone: 0086 28 85422114 lat: 30.66667 lon: 104.06667 hasResults: False