hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06295913 id: HYTOLIVE15 briefTitle: Hydroxytyrosol Dietary Supplement and Prevention of Age-Related Diseases acronym: HYTOLIVE15 overallStatus: RECRUITING date: 2024-03 date: 2024-07 date: 2024-12 date: 2024-03-06 date: 2024-03-06 name: National Research Council, Spain class: OTHER_GOV name: Genosa I+D briefSummary: The primary objective of this study is to ascertain the effects of chronic consumption of a hydroxytyrosol-rich extract from olive (Hytolive®) in a population at high risk of developing age-related pathologies such as type 2 diabetes and cardiovascular diseases. The markers measured will be associated with oxidative stress, inflammation, and homeostasis glucose and lipid profiles. Improvements in these parameters could potentially prevent the onset of pathologies associated with aging. conditions: Overweight conditions: PreDiabetes studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Group 1, hydroxytyrosol-rich extract pill (Hytolive®); Group 2, placebo pill primaryPurpose: BASIC_SCIENCE masking: TRIPLE maskingDescription: Participants will be randomly allocated to treatment A and B. Both pills will have the same aspect and will be packed similarly whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 50 type: ESTIMATED name: Group 1, hydroxytyrosol-rich extract capsule (Hytolive®) name: Group 2, capsule of placebo measure: LDL-ox as marker of oxidative status measure: Emotional well-being determined by Warwick-Edinburgh Mental Well-being Scale measure: Sleep quality determined by Pittsburgh Sleep Quality Index measure: Fatigue test determined by Borg Rating Of Perceived Exertion measure: Fasting glucose measure: Fasting insulin measure: Glycated hemoglobin (HbA1c) measure: Glucagon-like peptide-1 (GLP-1) measure: Total cholesterol measure: High density lipoproteins (HDL) measure: Low density lipoproteins (LDL) triglicéridos, apoliporpotein A1 and B) measure: Triglycerides measure: Apoliporpotein A1 measure: Apoliporpotein B measure: Total antioxidant status (TAS) measure: Total oxidative status (TOS) measure: Oxides of nitrogen (NOx) measure: Thiobarbituric acid reactive substances (TBARS) measure: C reactive protein measure: Interleukine 6 (IL-6) measure: Tumor necrosis factor alpha (TNF-α) measure: Interleukine 10 (IL-10) measure: Alanine aminotransfesare (transaminases ALT) measure: Aspartate aminotransferase (transaminase AST) sex: ALL minimumAge: 40 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Institute of Food Science, Technology and Nutrition, National Research Council (ICTAN-CSIC) status: RECRUITING city: Madrid state: Comunidad Autónoma De Madrid zip: 28040 country: Spain name: Raquel Mateos, PhD role: CONTACT phone: +34 915492300 phoneExt: 436341 email: raquel.mateos@ictan.csic.es name: Mª Ángeles Martín, PhD role: CONTACT phone: +34 915492300 phoneExt: 436340 email: amartina@ictan.csic.es lat: 40.4165 lon: -3.70256 hasResults: False
nctId: NCT06295900 id: 19.10.2023/63 briefTitle: The Effect of Aromatherapy Massage on Sleep Quality overallStatus: RECRUITING date: 2024-01-05 date: 2024-12 date: 2024-12 date: 2024-03-06 date: 2024-03-06 name: Nilgün Erdoğan class: OTHER briefSummary: Sleep disturbance is one of the most common complaints of patients admitted to ICU. Insufficient sleep in intensive care units may be associated with environmental reasons such as excessive light at night, loud warning sounds and mechanical ventilation alarms, as well as non-environmental factors, including the situation at the time of admission. Sleep assessment is subjective in nature, so it is difficult to perform in the ICU. Since communication with the patient is prevented, clear information about perceived rest and disturbing factors cannot be provided. For this reason, night rest is an issue that is often forgotten and ignored. This study applied a mixture of lavender, medicinal chamomile and neroli oil (in 20 ml of sweet almond oil; lavender oil 2 drops, medicinal chamomile 4 drops, neroli oil 6 drops) to patients who were monitored in intensive care on high-flow and oxygen, once a day for three days. This study will be conducted to determine the effect of aromatherapy massage applied for a total of 30 minutes on sleep quality. conditions: Diabetes Mellitus conditions: Respiratory Failure conditions: Pneumonia conditions: Respiratory Disease conditions: Stroke, Ischemic studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: It will be conducted as a randomized controlled single-blind study primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 62 type: ESTIMATED name: Intervention 1 Group name: Intervention 2 Group name: Placebo Control Group measure: Patient Introduction Form measure: Patient Follow-up Form measure: Visual Comparison Sleep Scale sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ömer Halisdemir University Training and Research Hospital status: RECRUITING city: Nigde zip: 51100 country: Turkey name: nilgun erdogan, researcher role: CONTACT phone: 5312599220 email: nilgunerdogan37@gmail.com lat: 37.96583 lon: 34.67935 hasResults: False
nctId: NCT06295887 id: E-2402 briefTitle: Educational Efficacy of VR vs. Simulator in Emergency Medical Training overallStatus: NOT_YET_RECRUITING date: 2024-04-13 date: 2025-02-28 date: 2025-12-31 date: 2024-03-06 date: 2024-03-08 name: Seoul National University Hospital class: OTHER name: Seoul National University briefSummary: It has not been revealed which is more effective: an education program using virtual reality technology or a simulation education program using Sim-man.
After the classes and surveys are completed for each group, the participants will be able to receive other educational methods if they wish. conditions: Simulation Training studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: control group vs. test group, 1:1 primaryPurpose: OTHER masking: NONE count: 166 type: ESTIMATED name: Educational Program using VR or simulator designed to improve medical intern's performance managing emergency situation measure: self-rated confidence for managing emergency situation measure: self-rated confidence for managing emergency situation measure: performance in managing emergency situation measure: usability of Virtual Reality simulation program using User Experience Questionnaire Short measure: usability of Virtual Reality simulation program using Simulator Sickness Questionnaire measure: usability of Virtual Reality simulation program using System Usability Scale sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06295874 id: 12.10.2022/50 briefTitle: The Effect of Aromatherapy Massage on Pain, Anxiety and Comfort overallStatus: RECRUITING date: 2023-01-05 date: 2024-08-30 date: 2024-08-30 date: 2024-03-06 date: 2024-03-06 name: Nilgün Erdoğan class: OTHER briefSummary: Patients in the intensive care unit (ICU) experience physical and psychological discomfort, including pain. Anxiety is a condition frequently encountered in the ICU. The hospital environment, especially the ICU, is reported as a significant cause of anxiety for patients. Comfort is a holistic, subjective and multidimensional concept that is affected by physical, environmental, social and psycho-spiritual contexts and changes over time and space. Comfort in intensive care is often associated with pain relief and end-of-life care. Assessment tools have been developed to measure patient comfort in the ICU, including levels of pain, delirium, and sedation. This work; Patients who are monitored in intensive care under high-flow and oxygen are treated with a mixture of lavender, thyme and eucalyptus oil (20 ml; lavender oil 5 drops, thyme oil 4 drops, eucalyptus oil 3 drops and 20 ml almond oil) twice a day for three days. This study was conducted to determine the effect of aromatherapy massage applied for a total of 30 minutes on some physiological parameters, pain, anxiety and intensive care comfort of the patients. conditions: Respiratory Insufficiency conditions: Pulmonary Disease, Chronic Obstructive conditions: Diabetes Mellitus, Type 2 conditions: High Blood Pressure conditions: Stroke, Ischemic studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: randomized controlled single blind study primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 61 type: ESTIMATED name: Effect of aromatherapy massage on vital signs, pain, anxiety and comfort level measure: Patient Introduction Form measure: Patient Follow-up Form measure: Drug Monitoring Form measure: Visual Pain Scale measure: Face Anxiety Scale measure: Comfort Rating Scale sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ömer Halisdemir University Training and Research Hospital status: RECRUITING city: Nigde zip: 51100 country: Turkey name: nilgun erdogan, researcher role: CONTACT phone: 5312599220 email: nilgunerdogan37@gmail.com lat: 37.96583 lon: 34.67935 hasResults: False
nctId: NCT06295861 id: 2023-1194 briefTitle: Prospective Cohort Study of Panvascular Disease overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-21 date: 2028-11-30 date: 2028-12-31 date: 2024-03-06 date: 2024-03-06 name: Second Affiliated Hospital, School of Medicine, Zhejiang University class: OTHER briefSummary: To construct a comprehensive big data platform for Chinese people with panvascular disease, and establish a Chinese panvascular disease oriented to guide treatment decisions Cohort and imaging, biological database; According to the clinical features, morphological structure, pathological characteristics of panvascularization, vascular age As the core of the evaluation, a standard evaluation system and a risk prediction model of intervention technology suitable for the diagnosis and treatment of patients with panvascular disease in China were established. Into the Further optimize the treatment strategies, protocols and clinical pathways for panvascular disease to improve patient prognosis and promote its application. conditions: ASCVD studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 50000 type: ESTIMATED name: no different intervention between the two cohort. measure: Cardiovascular adverse events measure: Cardiovascular mortality measure: Rate of receiving vascular revascularization measure: Readmission rate for vascular reasons sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Cardiology, The Second Affiliated Hospital, School of Medicine, Zhejiang University city: Hangzhou state: Zhejiang zip: 310000 country: China lat: 30.29365 lon: 120.16142 facility: Second Affiliated Hospital, School of Medicine, Zhejiang University city: Hangzhou state: Zhejiang zip: 310000 country: China lat: 30.29365 lon: 120.16142 hasResults: False
nctId: NCT06295848 id: KayseriCH005 briefTitle: The Effects of Cardiac Rehabilitation Programme in Hypertensive Rheumatoid Arthritis Patients acronym: CARDIRA overallStatus: RECRUITING date: 2022-12-15 date: 2024-04-15 date: 2024-06-15 date: 2024-03-06 date: 2024-03-28 name: Kayseri City Hospital class: OTHER_GOV briefSummary: The aim of this study is to investigate the beneficial impacts of the 6-week standardized CR program applied to hypertensive RA patients whose disease activity is under control with regular pharmacological treatment.
Subjects will be randomly assigned to one of two groups: 1.) standard of care (SOC) treatment or 2.) SOC plus a 6 week CR program. conditions: Cardiac Rehabilitation conditions: Rheumatoid Arthritis conditions: Hypertension studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 40 type: ESTIMATED name: Exercise measure: Framingham Risk Score(FRS) measure: QRISK-3 Risk Score measure: 24-Hour Ambulatory Blood Pressure measure: DAS28 measure: Maximal oxygen consumption (VO2max) measure: The Six-Minute Walk Test (6MWT) measure: The 36-Item Short Form Survey (SF-36) measure: International Physical Activity Questionnaire (IPAQ) - Short Form measure: Beck Depression Inventory (BDI) sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Health Sciences University, Kayseri Medicine Faculty status: RECRUITING city: Kayseri state: Kocasinan zip: 38080 country: Turkey name: HAVVA TALAY ÇALIŞ, PROFESSOR role: CONTACT phone: +905326874541 email: htalaycalis@yahoo.com name: PROFESSOR role: CONTACT lat: 38.73222 lon: 35.48528 hasResults: False
nctId: NCT06295835 id: CS-2024-0001 briefTitle: Method Comparison Study for Measuring Potassium (K) and Ionized Calcium (iCa) in Blood overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-09 date: 2024-12 date: 2024-03-06 date: 2024-03-22 name: Abbott Point of Care class: INDUSTRY briefSummary: Method comparison study for Potassium (K) and ionized calcium (iCa). conditions: Potassium (K) and Ionized Calcium (iCa) in Capillary Whole Blood studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Capillary whole blood specimens will be tested in duplicate on the i-STAT 1 Analyzer with the CG8+ cartridge and a blood analyte testing comparator device. primaryPurpose: DIAGNOSTIC masking: NONE count: 200 type: ESTIMATED name: Fingerstick blood draw measure: Performance comparison measure: Performance comparison sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06295822 id: CMUH112-REC2-063 briefTitle: The Effectiveness of Chinese Medicine Nuan-gong-ye on Primary Dysmenorrhea overallStatus: RECRUITING date: 2024-03-04 date: 2025-08-31 date: 2026-02-28 date: 2024-03-06 date: 2024-04-10 name: China Medical University Hospital class: OTHER briefSummary: Primary dysmenorrhea is a common under-diagnosed complaint, with a prevalence of about 45-95% in women of childbearing age and about 10-25% in severe cases. Menstrual pain can be classified as primary or secondary. Primary menstrual pain is a crampy pain in the lower abdomen without any pelvic pathology, which usually occurs 6 to 12 months after the first menstruation. Primary menstrual pain is usually most severe on the first day of the menstrual cycle and lasts for 8 to 72 hours. The cause is still unknown, but studies suggest that it may be related to increased prostaglandins, which cause painful contractions of the uterus. The pain is often accompanied by other menstrual discomfort symptoms, including headache, breast tenderness, drowsiness, nausea, vomiting, constipation or diarrhea, and psychological anxiety, depression or irritability. In the case of secondary menstrual pain, there are clear pelvic pathologies, such as endometriosis, uterine fibroids, and pelvic inflammatory disease. conditions: Chinese Medicine conditions: Primary Dysmenorrhea studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 82 type: ESTIMATED name: Nuan-gong-ye name: Placebo measure: Visual Analogue Scale (VAS) measure: Short Form McGill Pain Questionnaire (MPQ-SF) sex: FEMALE minimumAge: 20 Years maximumAge: 40 Years stdAges: ADULT facility: China Medical University Hospital status: RECRUITING city: Taichung zip: 404 country: Taiwan name: HSUAN HSUAN WU role: CONTACT phone: +886928030693 email: whh900710@gmail.com lat: 24.1469 lon: 120.6839 hasResults: False
nctId: NCT06295796 id: 8527-008 id: MK-8527-008 type: OTHER domain: Merck briefTitle: A Study of MK-8527 in Participants With Moderate and Severe Renal Impairment (MK-8527-008) overallStatus: NOT_YET_RECRUITING date: 2024-06-17 date: 2025-04-14 date: 2025-04-14 date: 2024-03-06 date: 2024-04-26 name: Merck Sharp & Dohme LLC class: INDUSTRY briefSummary: The goal of this study is to evaluate the effect of moderate and severe renal impairment (RI) on the pharmacokinetics (PK), safety, and tolerability of MK-8527. There will be no hypothesis testing in the study. conditions: Renal Impairment studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 18 type: ESTIMATED name: MK-8527 measure: Area under the concentration versus time curve from time 0 to last quantifiable sample (AUC0-last) of MK-8527 in plasma measure: Area under the concentration versus time curve from time 0 to infinity (AUC0-inf) of MK-8527 in plasma measure: Maximum concentration (Cmax) of MK-8527 in plasma measure: Time to Maximum concentration (Tmax) of MK-8527 in plasma measure: Apparent terminal half-life (t1/2) of MK-8527 in plasma measure: Apparent Clearance (CL/F) of MK-8527 in plasma measure: Apparent volume of distribution during terminal phase (Vz/F) of MK-8527 in plasma measure: Number of participants who experience one or more adverse events (AEs) measure: Number of participants who discontinue study due to an AE measure: AUC0-last of MK-8527-triphosphate (TP) in peripheral blood mononuclear cells (PBMCs) measure: AUC0-inf of MK-8527-TP in PBMCs measure: Cmax of MK-8527-TP in PBMCs measure: Concentration at 168 hours (C168) of MK-8527-TP in PBMCs measure: Concentration at 672 hours (C672) of MK-8527-TP in PBMCs measure: Tmax of MK-8527-TP in PBMCs measure: t1/2 of MK-8527-TP in PBMCs sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06295783 id: 2023-1059 id: NCI-2024-01955 type: OTHER domain: NCI-CTRP Clinical Registry briefTitle: Prospective Evaluation of the Relation Between Different Questionnaires Measuring Radiation-induced Side-effect overallStatus: NOT_YET_RECRUITING date: 2024-08-31 date: 2025-02-01 date: 2027-02-01 date: 2024-03-06 date: 2024-03-06 name: M.D. Anderson Cancer Center class: OTHER briefSummary: To learn more about how you would rate the intensity or severity of your symptoms during or after radiation therapy using questionnaires with different rating scales. conditions: Radiation studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 300 type: ESTIMATED name: MDASI-HN name: EORTC QLQ-C30 name: EORTC HN35 measure: Safety and adverse events (AEs) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: MD Anderson Cancer Center city: Houston state: Texas zip: 77030 country: United States name: Amy Moreno, MD role: CONTACT phone: 713-745-4590 email: akmoreno@mdanderson.org name: Amy Moreno, MD role: PRINCIPAL_INVESTIGATOR lat: 29.76328 lon: -95.36327 hasResults: False
nctId: NCT06295770 id: 23-006712 briefTitle: Obinutuzumab in Treatment of Fibrillary Glomerulonephritis overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2027-04-01 date: 2024-03-06 date: 2024-03-06 name: Mayo Clinic class: OTHER briefSummary: The purpose of this research is to learn if Obinutuzumab is effective and safe in treating patients with fibrillary glomerulonephritis (FGN). conditions: Fibrillary Glomerulonephritis studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 20 type: ESTIMATED name: Obinutuzumab measure: Change in proteinuria from baseline to 12 months post treatment with Obinutuzumab measure: Change in proteinuria from baseline to 6 months post treatment with Obinutuzumab measure: Rate of complete or partial remission measure: Improvement in serum albumin measure: Stabilization of kidney function measure: Serious Adverse Events (SAEs) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mayo Clinic city: Rochester state: Minnesota zip: 55905 country: United States name: Angela Reinke role: CONTACT phone: 507-266-1047 email: Reinke.Angela@mayo.edu name: Nicholas Geroux role: CONTACT phone: 507-266-0956 email: Geroux.Nicholas@mayo.edu name: Ladan Zand role: PRINCIPAL_INVESTIGATOR lat: 44.02163 lon: -92.4699 hasResults: False
nctId: NCT06295757 id: 2023LS102 briefTitle: Effects of Relighting on Smoke Toxicant Deliveries and Subjective Smoking Measures overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-01-01 date: 2027-01-01 date: 2024-03-06 date: 2024-03-06 name: Masonic Cancer Center, University of Minnesota class: OTHER name: National Institutes of Health (NIH) briefSummary: Characterize effects of relighting on smoke toxicant deliveries and subjective smoking measures. This will be a within-subject comparison in a single experimental group of 30 smokers who report engaging in relighting behaviors. We will assess smoking intensity for relit and non-relit (i.e., smoked continuously without relighting) cigarettes in the natural environment and will conduct in-clinic measurements of smoking topography and subjective responses for relit and non-relit cigarettes. Information on relighting patterns and smoking topography collected from each participant will be used to compare machine-measured smoke yields of key harmful constituents when their usual cigarettes are smoked with and without relighting. Hypothesis: Relit cigarettes will produce higher levels of toxicants than non-relit cigarettes. conditions: Tobacco Use conditions: Cigarette Smoking conditions: Nicotine Dependence studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: OTHER masking: NONE count: 30 type: ESTIMATED name: Cigarettes measure: Average Nicotine Level measure: Average Puff Volume sex: ALL minimumAge: 21 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06295744 id: 2023-1724 id: Protocol Version 2/5/2024 type: OTHER domain: UW Madison id: A533300 type: OTHER domain: UW Madison id: UW23114 type: REGISTRY domain: UWCCC OnCore ID briefTitle: Outcomes and Cosmesis With Whole Breast Irradiation and Boost overallStatus: RECRUITING date: 2024-04-17 date: 2029-02 date: 2032-02 date: 2024-03-06 date: 2024-04-24 name: University of Wisconsin, Madison class: OTHER briefSummary: This study is being done to evaluate cosmetic, patient-reported outcome measures (PROMs), and toxicities for women undergoing ultra-short whole breast irradiation (WBI) therapy with simultaneous integrated boost (SIB). 50 participants will be on study for up to 60 months. conditions: Early-stage Breast Cancer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 50 type: ESTIMATED name: Radiation Therapy measure: Harvard Breast Cosmesis Scale Score measure: Change in BREAST-Q Score measure: Incidence of Acute Toxicities measure: Incidence of Late Toxicities measure: Ipsilateral Breast Tumor Recurrence-Free Survival measure: Overall Survival (OS) sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: UW Carbone Cancer Center status: RECRUITING city: Madison state: Wisconsin zip: 53792 country: United States lat: 43.07305 lon: -89.40123 hasResults: False