hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06261437 id: M-11053 id: MO230060 type: OTHER_GRANT domain: Military Operational Medicine Research Program (MOMRP) briefTitle: Effect of Ration Formulations on Warfighter Energy Balance and Physical Performance During a Field Training Exercise overallStatus: NOT_YET_RECRUITING date: 2024-02-22 date: 2024-03-04 date: 2024-03-04 date: 2024-02-15 date: 2024-02-15 name: United States Army Research Institute of Environmental Medicine class: FED briefSummary: The goal of this randomized clinical trial is to determine the effects of consuming the Close Combat Assault Ration (CCAR) compared to the First Strike Ration (FSR) during a 7-day strenuous military training on energy intake and energy balance in healthy, Active Duty Warfighters.
Participants will be asked to consume either the CCAR or FSR as the sole nutrition source during a 7-day field training exercise (FTX). The vertical jump test, running-based anaerobic sprint test, and lower-body strength pull will be conducted pre and post the 7-day FTX to assess physical performance. Energy expenditure and intake will be measured by the doubly-labelled water method and dietary logs, respectively. Surveys will be completed to assess ration acceptability and gastrointestinal symptoms.
Researchers will compare the CCAR and FSR groups to see if their consumption impacted energy intake, energy balance, physical performance, ration acceptance, or gastrointestinal side effects. conditions: Healthy Volunteers studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: SINGLE whoMasked: PARTICIPANT count: 60 type: ESTIMATED name: CCAR name: FSR measure: Energy intake measure: Energy expenditure measure: Energy balance measure: Physical performance (vertical jump) measure: Physical performance (peak power) measure: Physical performance (Anaerobic capacity) measure: Physical performance (lower-body strength) measure: Food acceptance scale measure: Gastrointestinal Quality of Life Index measure: Hunger and Satiety Visual Analog Scales sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: U.S. Army Research Institute of Environmental Medicine city: Natick state: Massachusetts zip: 01760 country: United States name: USARIEM role: CONTACT phone: 508-206-2200 email: usarmy.natick.medcom-usariem.mbx.usariem-webmaster@health.mil name: Michael A Dawson, PhD role: PRINCIPAL_INVESTIGATOR lat: 42.28343 lon: -71.3495 hasResults: False
nctId: NCT06261411 id: 999430 id: FOU2024-00038 type: REGISTRY domain: Forskning och Utveckling (Region Uppsala) briefTitle: Lung Ultrasound as Alternative to Radiation in Thoracic Surgery acronym: LUS-ART overallStatus: ENROLLING_BY_INVITATION date: 2024-02-12 date: 2025-04-30 date: 2025-04-30 date: 2024-02-15 date: 2024-02-20 name: Uppsala University Hospital class: OTHER briefSummary: This projects aim is to study the effects of substitute conventional chest x-ray with lung ultrasound for patients undergoing thoracic surgery.
Participants in the study will be randomized to either ultrasound or routine chest x-ray as the primary method of diagnosis after having received surgery to their lungs. conditions: Thoracic Surgery conditions: Ultrasonography studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Case-Control primaryPurpose: DIAGNOSTIC masking: SINGLE maskingDescription: Inter-rater variability will be masked. whoMasked: OUTCOMES_ASSESSOR count: 110 type: ESTIMATED name: Lung Ultrasound measure: Reduction in chest x-ray measure: Re-insertion of chest tube measure: Delayed removal of chest tube measure: Time to chest tube removal measure: Patient Satisfaction measure: Missed Care measure: Inter-rater variability sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Uppsala Akademiska sjukhuset city: Uppsala state: Uppland zip: 751 85 country: Sweden lat: 59.85882 lon: 17.63889 typeAbbrev: Prot hasProtocol: True hasSap: False hasIcf: False label: Study Protocol date: 2024-02-02 uploadDate: 2024-02-07T05:12 filename: Prot_000.pdf size: 806384 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2024-02-02 uploadDate: 2024-02-07T05:12 filename: ICF_001.pdf size: 350352 hasResults: False
nctId: NCT06261398 id: 2023H0065 briefTitle: Better Birth Outcomes Through Technology, Education, and Reporting acronym: BETTER overallStatus: RECRUITING date: 2024-02-26 date: 2027-09 date: 2028-03 date: 2024-02-15 date: 2024-02-28 name: Ohio State University class: OTHER name: American Heart Association briefSummary: This is a pragmatic randomized control trial to evaluate the BETTER intervention compared to standard obstetrical care (control) to determine whether it helps to reduce maternal anemia and other adverse pregnancy outcomes. The BETTER intervention includes one motivational interviewing session and bi-weekly text messages to encourage patients to connect with resources that address their social needs, including housing, food, and transportation. Quantitative data will be used to study participant outcomes, including surveys, and electronic health record data. conditions: Pregnancy conditions: Maternal Anemia conditions: Pre-Term Birth conditions: Hypertensive Disorders studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 550 type: ESTIMATED name: BETTER: motivational interviewing and text messaging name: Standard of care measure: Incidence of maternal anemia measure: Incidence of Pre-term birth measure: Incidence of Hypertensive disorders of pregnancy measure: Incidence of infection measure: Incidence of Cesarean Delivery measure: Incidence of Postpartum hemorrhage measure: Incidence Severe maternal morbidity measure: Incidence of maternal mortality measure: Incidence of Small for gestational age birth measure: Incidence of Large for gestational age measure: Incidence of NICU admission measure: Incidence of Perinatal mortality measure: Incidence of Prenatal care visits measure: Incidence of Antepartum admission measure: Length of stay (days) measure: Postpartum re-admission sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Ohio State University Outpatient Care East status: RECRUITING city: Columbus state: Ohio zip: 43203 country: United States name: William Grobman, MD, MBA role: CONTACT phone: 614-293-4929 email: William.Grobman@osumc.edu name: Anna Bartholomew, BSN, RN, MPH role: CONTACT phone: 614-685-3229 email: Anna.Bartholomew@osumc.edu lat: 39.96118 lon: -82.99879 facility: McCampbell Hall status: RECRUITING city: Columbus state: Ohio zip: 43210 country: United States name: William Grobman, MD, MBA role: CONTACT phone: 614-293-4929 email: William.Grobman@osumc.edu name: Anna Bartholomew, BSN, RN, MPH role: CONTACT phone: 614-685-3229 email: Anna.Bartholomew@osumc.edu lat: 39.96118 lon: -82.99879 facility: The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine status: RECRUITING city: Columbus state: Ohio zip: 43210 country: United States name: William Grobman, MD, MBA role: CONTACT phone: 614-293-4929 email: William.Grobman@osumc.edu name: Anna Bartholomew, BSN, RN, MPH role: CONTACT phone: 614-685-3229 email: Anna.Bartholomew@osumc.edu lat: 39.96118 lon: -82.99879 hasResults: False
nctId: NCT06261385 id: typology briefTitle: Development of Typology-based Smoking Relapse Prevention: A Q-methodology and a Pilot Randomized Controlled Trial overallStatus: RECRUITING date: 2024-01-23 date: 2024-10-31 date: 2025-01-31 date: 2024-02-15 date: 2024-02-15 name: The University of Hong Kong class: OTHER name: Health and Medical Research Fund briefSummary: This study aims to develop a typology-based intervention delivered by smoking cessation (SC) counselors to prevent smoking relapse in ex-smokers who recently quit. The two main research questions include (1) Can a typology-based smoking relapse prevention intervention be feasible and accepted by the smokers and SC counselors who deliver the new intervention? (2) What is the preliminary evidence on the efficacy of the typology-based smoking relapse prevention to increase tobacco abstinence in ex-smokers who have recently quit? If the intervention shows at least a small effect size (i.e. risk ratio\>1.3), or the intervention is feasible while modifications can potentially increase the efficacy, a future definitive RCT is warranted. conditions: Smoking Cessation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: SINGLE maskingDescription: Outcome assessors at the telephone follow-up are blinded to the group allocation. whoMasked: OUTCOMES_ASSESSOR count: 510 type: ESTIMATED name: typology-based intervention measure: self-reported abstinence in the past 30 days at 2-month follow-up measure: iScreen OFD Cotinine Saliva Test Kit (<30ng/ml) biochemical validated tobacco abstinence measure: the difference of the feasibility and acceptability score of the typology-based intervention between the intervention and control group. measure: Time required for the counselling measure: Compliance rate of the SC counsellors in following the intervention protocol measure: Proportion of screened clients who participate in the RCT measure: Dropout rate of the participants who consent to the RCT measure: Satisfaction on the SC counsellors measure: Satisfaction on the e-messages measure: Frequency of reading the e-messages measure: Perceived effectiveness on the intervention measure: Satisfaction on the enrolment procedures measure: Intention to recommend the intervention to other smokers measure: Satisfaction about the intervention from SC counsellor measure: Perceived appropriateness of the intervention length from SC counsellor measure: Satisfaction on the enrolment procedures from SC counsellor measure: Perceived effectiveness of the screening tool from SC counsellor measure: Perceived clients' acceptance of the intervention from SC counsellor measure: Intention to apply this intervention in other clients from SC counsellor sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: LKS Faculty of Medicine status: RECRUITING city: Hong Kong zip: 00 country: Hong Kong name: Derek YT Cheung, PhD role: CONTACT phone: +852 3917 6652 email: derekcheung@hku.hk lat: 22.27832 lon: 114.17469 hasResults: False
nctId: NCT06261372 id: KY2023PJ204 briefTitle: Mindfulness Meditation Combined With Progressive Muscle Relaxation Training for Uremic Sarcopenia overallStatus: COMPLETED date: 2023-08-15 date: 2023-11-15 date: 2023-11-15 date: 2024-02-15 date: 2024-02-15 name: Ningbo Medical Center Lihuili Hospital class: OTHER_GOV briefSummary: To study the effect of mindfulness meditation combined with progressive muscle relaxation training on clinical efficacy and quality of life in maintenance hemodialysis (MHD) patients with sarcopenia. Eligible sarcopenic patients in our hospital were randomly assigned to a control group (n = 24) and an intervention group (n = 25). The control group received conventional dialysis treatment, while the intervention group received mindfulness meditation combined with progressive muscle relaxation training during the interdialysis period in addition to conventional dialysis treatment. The effect of the intervention was evaluated after 12 weeks.To observe whether the combined intervention training can improve the motor ability and quality of life of patients with sarcopenia in a short period of time. conditions: Hemodialysis Patients With Sarcopenia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 49 type: ACTUAL name: The mindfulness meditation combined with progressive muscle relaxation training . measure: 10 sit-to-stand test in seconds measure: Grip strength in kilograms measure: 6-meter walk test in metre per second measure: KDQOLTM(Kidney Disease Quality of Life short Form) score measure: interleukin-6 (IL-6) measure: high-sensitivity C-reactive protein (hsCRP) measure: albumin(ALB) measure: prealbumin (PA） sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Li Huili Hospital, Ningbo Medical Center city: Ningbo state: Zhejiang zip: 315046 country: China lat: 29.87819 lon: 121.54945 hasResults: False
nctId: NCT06261359 id: CEND1-202 briefTitle: A Study of CEND-1 With Chemotherapy as First-Line Therapy in Patients With Pancreatic Ductal Adenocarcinoma overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2025-04 date: 2026-10 date: 2024-02-15 date: 2024-02-15 name: Qilu Pharmaceutical Co., Ltd. class: INDUSTRY briefSummary: The purpose of this study is to evaluate the efficacy and safety of CEND-1 in combination with gemcitabine/nab-paclitaxel versus gemcitabine/nab-paclitaxel and placebo as first-line treatment in patients with Locally Advanced Unresectable or Metastatic Pancreatic Ductal Adenocarcinoma. conditions: Pancreatic Ductal Adenocarcinoma (PDAC) studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 120 type: ESTIMATED name: CEND-1 name: Gemcitabine name: Nab paclitaxel measure: Objective response rate (ORR) measure: Overall Survival (OS) measure: Progression Free Survival(PFS) measure: 6-month PFS rate measure: Duration Of Response (DOR) measure: Disease Control Rate (DCR) measure: Incidence of AEs, SAEs and treatment-emergent adverse events (TEAEs) sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Chinese People's Liberation Army (PLA) General Hospital city: Beijing state: Beijing zip: 100000 country: China lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06261346 id: 20230420 briefTitle: Plasma Rich in Growth Factors in Corneal Endothelial Transplantation overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2026-04-30 date: 2026-06-30 date: 2024-02-15 date: 2024-04-02 name: Price Vision Group class: INDUSTRY briefSummary: The purpose of the study is to determine the safety and efficacy of brief intraoperative corneal endothelial graft incubation in plasma rich in growth factors (PRGF) for reducing postoperative endothelial cell loss. Subjects scheduled for endothelial keratoplasty will be enrolled and randomized to have the graft incubated in PRGF or not prior to graft implantation. The main outcome is the percentage central corneal endothelial cell loss 6 months after surgery. conditions: Fuchs' Endothelial Dystrophy conditions: Corneal Edema studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 100 type: ESTIMATED name: PRGF measure: Endothelial cell loss at 6 months measure: Corneal endothelial cell density measure: Endothelial cell loss measure: Best corrected visual acuity measure: Re-bubble rate sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Bascom Palmer Eye Institute city: Miami state: Florida zip: 33136 country: United States name: Alfonso Sabater, MD role: CONTACT phone: 305-326-6326 email: asabater@med.miami.edu lat: 25.77427 lon: -80.19366 facility: Price Vision Group city: Indianapolis state: Indiana zip: 46260 country: United States name: Marianne Price, PhD role: CONTACT phone: 317-814-2990 email: mprice@cornea.org lat: 39.76838 lon: -86.15804 hasResults: False
nctId: NCT06261333 id: 23-11519-BO briefTitle: Quality of Life in Patients With Hemorrhagic Telangiectasia overallStatus: ENROLLING_BY_INVITATION date: 2024-01-22 date: 2024-12-31 date: 2025-12-31 date: 2024-02-15 date: 2024-02-15 name: University Hospital, Essen class: OTHER briefSummary: Hereditary Hemorrhagic Telangiectasia (HHT), also known as Osler's disease, is a genetic disorder that leads to abnormal blood vessel formations. It primarily affects blood vessels in the skin, mucous membranes, and internal organs. The disease can be clinically diagnosed using the Curaçao criteria (1. Positive family history of HHT, 2. Recurrent and spontaneous epistaxis, 3. Multiple typical telangiectasias, 4. Organ involvement with vascular malformations, especially in the liver, lungs, gastrointestinal tract, or brain); if a patient meets at least 3 criteria, the diagnosis of HHT can be established.
Patients with HHT often have telangiectasias on their faces. Additionally, many patients suffer from anemia, which can result in a pale and potentially tired appearance. Patients with HHT may be less satisfied with their appearance due to the aesthetic changes in their faces and may also experience psychosocial impairment. To further investigate this, various validated questionnaires (FACE-Q©, PROMIS-Profile-29+2, EQ5D), as well as routinely collected clinical data (e.g., laboratory values including hemoglobin levels, Curaçao criteria, smoking status, alcohol consumption, and the Epistaxis Severity Score (ESS)) will be used. conditions: Hereditary Hemorrhagic Telangiectasia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 250 type: ESTIMATED name: Questionnaires measure: Quality of Life and Patient Satisfaction measured using the FACE-Questionnaire sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Departement of Otorhinolaryngology - Head and Neck Surgery University Hospital Essen city: Essen state: NRW zip: 45147 country: Germany lat: 51.45657 lon: 7.01228 hasResults: False
nctId: NCT06261320 id: 2023-506950-18-00 briefTitle: Mesotherapy Treatment of Irritable Bowel Syndrome acronym: MESOCOLO overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-28 date: 2025-12-31 date: 2026-01-31 date: 2024-02-15 date: 2024-04-05 name: Polyclinique de l'Europe class: OTHER briefSummary: Irritable bowel syndrome (IBS) is a gastrointestinal transit disorder characterized by chronic abdominal pain and impaired transit in the absence of demonstrated organic disease. Considered a non-fatal disease, its effects relate more to quality of life, work production and health care systems.
Several published case studies evaluating the effect of mesotherapy on improving the severity of the disease have demonstrated an improvement in the symptoms of this syndrome. Due to the limited number of case studies and the insufficient level of evidence to conclude, our study will therefore be a before-and-after intervention study, to evaluate the effect of four mesotherapy sessions on the treatment of IBS symptoms. conditions: Inflammatory Bowel Diseases studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 27 type: ACTUAL name: Mesotherapy with mesocaine, thiocolchicoside, amitriptyline, magnesium pidolate measure: Irritable Bowel Syndrome Symptom Severity Scale(IBS-SSS) measure: Functional Digestive Disorders Quality of Life questionnaire (FDDQL) measure: Pain evaluation measure: Global satisfaction measure: Anxiety evaluation : Questionnaire "Hospital anxiety and depression scale" sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Polyclinique de l'Europe city: Saint-Nazaire zip: 44600 country: France lat: 47.28333 lon: -2.2 hasResults: False
nctId: NCT06261307 id: 13462111 briefTitle: Language Development Deficits and Early Interactive Music Intervention acronym: BusyBaby overallStatus: RECRUITING date: 2024-03-11 date: 2026-03 date: 2027-03 date: 2024-02-15 date: 2024-04-05 name: University of Helsinki class: OTHER name: Folkhälsan Research Center name: Karolinska Institutet name: University of Turku name: University of Jyvaskyla name: Academy of Finland briefSummary: Investigators compare effects of 6-month music versus circus group interventions on language development in infants and toddlers with or without familial risk for dyslexia (anticipated total N=200). Effects of intervention timing, dyslexia risk and genetics, and social-emotional factors on the intervention outcomes are investigated. conditions: Dyslexia, Developmental conditions: Language Development Disorders conditions: Language Development studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The experimental arm will receive music training and the control arm will receive circus training. primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: A dedicated member of the research team will be in charge of randomization of the participants to the two intervention arms, to ensure blindness of other team members. This member will not act as an outcomes assessor or a care provider.
Outcomes assessors will be unaware of the intervention arm and risk status (dyslexia risk vs no risk) of the children; caregivers will be reminded not to mention these to the researcher. Person in charge of randomization keeps track of violations of outcome assessor blindness. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 200 type: ESTIMATED name: Music intervention name: Circus intervention measure: Infant-Toddler Checklist (ITC) measure: MacArthur-Bates Communicative Development Inventory (MCDI) 8-16mo measure: Mismatch response (MMR) speech, amplitude measure: Mismatch response (MMR) speech, latency measure: Mismatch response (MMR) speech, laterality measure: Obligatory event-related potential (ERP) speech, amplitude measure: Obligatory event-related potential (ERP) speech, latency measure: Obligatory event-related potential (ERP) speech, laterality measure: Infant-Toddler Checklist (ITC) follow-up measure: MacArthur-Bates Communicative Development Inventory (MCDI) 16-30mo follow-up measure: Mismatch response (MMR) speech, amplitude follow-up measure: Mismatch response (MMR) speech, latency follow-up measure: Mismatch response (MMR) speech, laterality follow-up measure: Obligatory event-related potential (ERP) speech, amplitude follow-up measure: Obligatory event-related potential (ERP) speech, latency follow-up measure: Obligatory event-related potential (ERP) speech, laterality follow-up measure: Reynell Developmental Language Scales III (RDLS-III) measure: Infant Behavior Questionnaire Revised short form (IBQ-R-sf) measure: Early Childhood Behavior Questionnaire short form (ECBQ-sf) measure: Parenting Stress Index Short Form (PSI-sf) measure: Brief Infant-Toddler Social Emotional Assessment (BITSEA) measure: Parental dyslexia status (dyslexia - no dyslexia) measure: Allele groupings for dyslexia susceptibility genes measure: Gross and fine motor development measure: Bayley Scales III Motor scale measure: Mismatch response (MMR) music, amplitude measure: Mismatch response (MMR) music, latency measure: Mismatch response (MMR) music, laterality measure: Obligatory event-related potential (ERP) music, amplitude measure: Obligatory event-related potential (ERP) music, latency measure: Obligatory event-related potential (ERP) music, laterality measure: Music test scores (three parts of MMBB-MB) measure: Music-related activities measure: Musical background of parents measure: Home literacy measure: Multilingualism measure: Screen time sex: ALL minimumAge: 8 Months maximumAge: 12 Months stdAges: CHILD facility: University of Helsinki status: RECRUITING city: Helsinki zip: 00014 country: Finland name: Paula Virtala, PhD role: CONTACT phone: +358408446907 email: paula.virtala@helsinki.fi lat: 60.16952 lon: 24.93545 hasResults: False