hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06363201 id: CAT2024/PED01 briefTitle: Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid Tumours overallStatus: NOT_YET_RECRUITING date: 2024-04-28 date: 2024-12-15 date: 2025-12-15 date: 2024-04-12 date: 2024-04-12 name: Catalysis SL class: INDUSTRY briefSummary: Exploratory study to evaluate the effect and safety of the use of Ocoxin® oral solution on the quality of life of paediatric patients with advanced stage solid tumours. conditions: Advanced Cancer conditions: Advanced Solid Tumor conditions: Lymphoma, Hodgkin conditions: Central Nervous System Tumor conditions: Sarcoma conditions: Germ Cell Tumor conditions: Pediatric Cancer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 40 type: ESTIMATED name: Ocoxin Oral solution measure: Quality of Life measure: Degree of toxicity related to oncospecific treatment measure: Nutritional Status measure: Presence of Adverse Events (AE) measure: Metabolic Status measure: Physical Status measure: Response to oncospecific treatment sex: ALL minimumAge: 7 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Hospital Escuela, Tegucigalpa (Honduras) city: Tegucigalpa state: Francisco Morazan zip: 504 country: Honduras name: Ingrid C. Arambú Elvir, Dr. role: CONTACT phone: 50498878486 email: ingridcarolinaa@yahoo.com name: Ingrid C. Arambú Elvir, Dr. role: PRINCIPAL_INVESTIGATOR name: Alejandra Elonor Zapata, Dr. role: SUB_INVESTIGATOR name: Clarissa L. Aguilar Molina, Dr. role: SUB_INVESTIGATOR name: Darío Vinicio Cáceres, Dr. role: SUB_INVESTIGATOR name: Gerardo Ismael Castro, Dr. role: SUB_INVESTIGATOR lat: 14.0818 lon: -87.20681 hasResults: False
nctId: NCT06363188 id: effect of ESWT on fractures briefTitle: The Impact of ESWT on Healing of Fractured Mandible overallStatus: RECRUITING date: 2024-02-01 date: 2024-08-01 date: 2025-08-30 date: 2024-04-12 date: 2024-04-12 name: Cairo University class: OTHER briefSummary: studying if using extracorporeal radial shockwave therapy as an adjuvant therapy help in accelerating the bone healing and regeneration in mandibular fractures by comparing it with the standard protocol for fractures fixation by plates and screws. conditions: Fractured Mandible Due to Trauma studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 10 type: ESTIMATED name: Radial Extracorporeal shockwave measure: bone healing (denisty of bone) measure: pain sensation sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Cairo Univeristy status: RECRUITING city: Cairo country: Egypt name: khloud nasr eldin, GP role: CONTACT phone: 01014919174 email: khloud.ahmed@dentistry.cu.edu.eg name: Emad Saied, prof. role: CONTACT phone: 01222117986 lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06363175 id: 8737 id: 343073 type: OTHER domain: Integrated Research Application system (IRAS) briefTitle: PREMs In Vascular SurgERy Enhancement Study acronym: PREMIERE overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-08-01 date: 2026-06-01 date: 2024-04-12 date: 2024-04-15 name: Cardiff and Vale University Health Board class: OTHER_GOV name: Welsh Value in Health Centre (WViHC) name: Centre for Healthcare Evaluation, Device Assessment, and Research (CEDAR) briefSummary: THE PROBLEM:
In the second phase, a larger number of vascular patients (100-300 depending on how long the 'draft' PREM is) from hospitals across Wales will complete the questionnaire. Statistical tests will look at the results to see if the questionnaire works well to capture patients' experiences. Based on these results, small changes will be made to make the 'draft' PREM better. This will make sure the 'final PREM' is ready for widespread use in Wales and beyond.
The patients' experience team at CAVUHB has reviewed our patients' materials. Our research team includes PPI co-applicants (DC and AH). DC a double amputee who has had many vascular operations. DC has experience raising awareness about vascular disease through public forums like the Limbless Association Charity and BBC Radio Wales. AH has issues with her leg due to smoking and had a keyhole operation to help with that. She had some problems after the procedure This is her first time as a PPI representative. DC and AH supported our research design and will be steering group members. Also, our research focuses on giving patients a voice and will include patients across Wales. A diverse group of patients will be involved across all stages of the PREM development. conditions: Vascular Diseases conditions: Patient Empowerment conditions: Patient Satisfaction conditions: Patient Engagement conditions: Surgery studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 330 type: ESTIMATED measure: Degree of Validity of the PREM measure: Degree of Reliability of the PREM measure: Degree of Responsiveness of the PREM measure: Degree of Feasibility of implementing the PREM in clinical practice sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Southeast Wales Vascular Network-Cardiff and Vale University Health Board city: Cardiff state: Wales country: United Kingdom lat: 51.48 lon: -3.18 hasResults: False
nctId: NCT06363162 id: LRR202404 briefTitle: Evaluate the Effectiveness and Safety of Raman IVD Analyzer in the Molecular Diagnosis of Gliomas During Surgery overallStatus: RECRUITING date: 2022-12-01 date: 2025-06-30 date: 2025-12-31 date: 2024-04-12 date: 2024-04-12 name: Beijing Tiantan Hospital class: OTHER name: West China Hospital name: The First Affiliated Hospital of Zhengzhou University name: Capital Medical University name: Jiangsu Raman Medical Equipment Co., Ltd. briefSummary: To distinguish various molecular subtypes of gliomas by spectra data obtained from Raman analyzer, including IDH mutant, 1p/19q-codeleted, ATRX deletion, TERT promoter mutation, MGMT promoter methylation, EGFR amplification, H3 K27-altered, TP53 mutant, PTEN deficiency, ki 67, AQP4, VEGF, and so on, comparing with the results of Immunohistochemistry or genetic test on the same brain tissue samples. conditions: Glioma studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: The same sample was diagnosed using Raman spectroscopy and immunohistochemistry or genetic test, respectively. Calculate the AUC, the accuracy, the sensitivity and specificity of a Raman analyzer using immunohistochemistry or genetic test results as the gold standard. primaryPurpose: DIAGNOSTIC masking: NONE maskingDescription: Blind assessment: Researchers using Raman analyzer during surgery are not aware of the subjects' preoperative diagnostic results, while researchers conducting immunohistochemistry or genetic test after surgery are not aware of the subjects' preoperative diagnostic results and the diagnostic results of Raman analyzer. count: 200 type: ESTIMATED name: Immunohistochemistry or genetic test measure: Area Under the Curve measure: Accuracy measure: Sensitivity measure: Specificity measure: Kappa coefficient measure: Time consumption for the Raman analyzer in detection measure: Adverse Event Incidence Rate measure: Serious Adverse Event Incidence Rate measure: Operator adverse events sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Beijing Tiantan Hospital status: RECRUITING city: Beijing state: Beijing zip: 100071 country: China name: Yinyan Wang, MD and PhD role: CONTACT phone: +86 13581698953 email: tiantanyinyan@126.com lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06363149 id: 2024-11-DM-136 briefTitle: Disseminated Intravascular Coagulation (DIC) Score and Organ Dysfunction in Septic Shock Patients overallStatus: RECRUITING date: 2024-04-12 date: 2025-09 date: 2025-09 date: 2024-04-12 date: 2024-04-16 name: Sanjay Gandhi Postgraduate Institute of Medical Sciences class: OTHER_GOV briefSummary: Septic shock is common complication in patients with critical illnesses, with higher incidence in low and medium income countries like ours. Disseminated intravascular coagulation (DIC) is also common in patients presenting to intensive care units. Further DIC is common coexisting condition seen in many patients presenting with sepsis and septic shock.
Understanding effects of DIC on organ dysfunction in septic shock patients can help to prognosticate and guide towards early intervention. Also, there is paucity of literature on effect of DIC score changes on organ dysfunction in patients with septic shock. conditions: Septic Shock conditions: Disseminated Intravascular Coagulation studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 60 type: ESTIMATED measure: Effect of Disseminated Intravascular Coagulation score changes on organ dysfunction in septic shock patients at day 7 measure: Effect of Disseminated Intravascular Coagulation score changes on organ dysfunction in septic shock patients at day 14 sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sanjay Gandhi Postgraduate Institute of Medical Sciences status: RECRUITING city: Lucknow state: Uttar Pradesh zip: 226014 country: India name: Mohan Gurjar, MD, PDCC role: CONTACT name: Dinesh Chandra, MD, DM role: CONTACT name: Mohan Gurjar, MD, PDCC role: PRINCIPAL_INVESTIGATOR name: Sanjay Chaudhary, MD role: SUB_INVESTIGATOR name: Dinesh Chandra, MD, DM role: PRINCIPAL_INVESTIGATOR lat: 26.83928 lon: 80.92313 hasResults: False
nctId: NCT06363136 id: 14.06.2023-111176 briefTitle: Foot Posture, Strength, Performance, and Postural Control in Isolated Gastrocnemius Tightness overallStatus: RECRUITING date: 2024-02-01 date: 2024-05-30 date: 2024-06-30 date: 2024-04-12 date: 2024-04-12 name: Bezmialem Vakif University class: OTHER briefSummary: Studies on gastrocnemius tightness in healthy children are limited, but there is evidence that ankle dorsiflexion decreases with increasing age in children. It is not known whether gastrocnemius tightness is a normal finding in children, but recurrent leg pain is common in children. It is also known that flexible flatfoot is a normal observation in developing children and that the medial longitudinal arch develops during the first decade of life. Both foot morphology and ankle dorsiflexion change in developing children; however, it is not known whether there is a relationship between them or not.
In the literature, there is no study evaluating foot posture, muscle strength, functional performance, and postural control in children with isolated gastrocnemius muscle tightness. It was planned to evaluate postural control using computerized dynamic posturography (Biodex Balance System), lower extremity muscle strength using a hand-held dynamometer, foot posture using the Foot Posture Index (FPI-6), and functional performance using single-foot-double-foot jump tests in healthy children with isolated gastrocnemius muscle tightness. conditions: Gastrocnemius Tightness conditions: Postural Control conditions: Muscle Strength conditions: Functional Performance conditions: Foot Posture studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: CROSS_SECTIONAL count: 28 type: ESTIMATED measure: Postural Control Assessment measure: Lower extremity muscle strength measurement measure: Foot posture assessment measure: Functional performance assessment sex: ALL minimumAge: 7 Years maximumAge: 16 Years stdAges: CHILD facility: Bezmialem Vakif University status: RECRUITING city: Istanbul country: Turkey name: Deniz Tuncer, PhD, PT role: CONTACT name: Fatma Eren, PT role: CONTACT name: Fatma Eren, PT role: SUB_INVESTIGATOR name: Deniz Tuncer, PhD, PT role: PRINCIPAL_INVESTIGATOR lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06363123 id: BFHHZML20240009 briefTitle: Plasma Metabolic Biomarkers for Multi-Cancer Diagnosis overallStatus: RECRUITING date: 2024-03-29 date: 2024-10 date: 2025-04 date: 2024-04-12 date: 2024-04-15 name: Beijing Friendship Hospital class: OTHER briefSummary: The aim of this observational study is to comprehensively analyze the metabolites in plasma samples from multi-cancer patients using advanced mass spectrometry detection technology, in conjunction with metabolomics approaches. The goal is to construct a plasma metabolite database for multi-cancer patients. Simultaneously, we will delve into the exploration and validation of a series of metabolic biomarkers for early multi-cancer diagnosis. The objective is to establish a safer, more convenient, and more sensitive early screening method, thereby providing a reliable scientific foundation and critical evidence for improving the early diagnostic process for individuals at high risk of multi-cancer. conditions: Lung Cancer conditions: Breast Cancer conditions: Colorectal Cancer conditions: Thyroid Cancer conditions: Gastric Cancer conditions: Cervical Cancer conditions: Liver Cancer conditions: Pancreatic Cancer conditions: Cholangiocarcinoma conditions: Prostate Cancer conditions: Esophageal Cancer conditions: Ovarian Cancer conditions: Renal Cell Carcinoma studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 2700 type: ESTIMATED measure: Plasma metabolite content sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Cancer Hospital Chinese Academy of Medical Sciences status: RECRUITING city: Beijing state: Beijing zip: 100021 country: China name: Yibin Xie, Ph.D. role: CONTACT lat: 39.9075 lon: 116.39723 facility: Beijing Friendship Hospital, Capital Medical University status: RECRUITING city: Beijing state: Beijing zip: 100050 country: China name: Li Min, Ph. D. role: CONTACT phone: +86 13552652141 email: minli@ccmu.edu.cn name: Bilian Kang, Ph.D. role: CONTACT phone: +86 18001218793 email: kbl@mail.ccmu.edu.cn lat: 39.9075 lon: 116.39723 facility: Hebei Tumor Hospital status: RECRUITING city: Shijiazhuang state: Hebei zip: 050010 country: China name: Lianmei Zhao, Ph.D. role: CONTACT lat: 38.04139 lon: 114.47861 facility: Zhejiang Cancer Hospital status: RECRUITING city: Hangzhou state: Zhejiang zip: 310022 country: China name: Qian Song, Ph.D. role: CONTACT lat: 30.29365 lon: 120.16142 hasResults: False
nctId: NCT06363110 id: 22724 briefTitle: An Observational Study to Learn More About Vericiguat Treatment Patterns and Its Safety in People With Chronic Heart Failure With Reduced Ejection Fraction in Routine Medical Care in the United States acronym: HOVER overallStatus: ACTIVE_NOT_RECRUITING date: 2024-04-10 date: 2024-06-30 date: 2024-06-30 date: 2024-04-12 date: 2024-04-16 name: Bayer class: INDUSTRY briefSummary: This is an observational study in which data already collected from people with chronic heart failure with reduced ejection fraction (HFrEF) are studied.
In this study, only available data from routine care are collected. No visits or tests are required as part of this study. conditions: Chronic Heart Failure With Reduced Ejection Fraction studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 1400 type: ESTIMATED name: Vericiguat (Verquvo, BAY1021189) measure: Number of patients having vericiguat daily dose of 2.5 mg, 5 mg and 10 mg at index date measure: Number of patients having daily dose of 10 mg/day within the 90 days after vericiguat initiation measure: Days from index date to first occurrence of 10 mg/day dose measure: Number of patients who received a dose of 2.5 mg/day, 5 mg/day and 10 mg/day, or discontinued drug therapy each day over the 90-day follow-up period measure: Number of patients having any Vericiguat up-titration within the 90 days after vericiguat initiation measure: Number of patients having specific titration scenarios within the 90 days after vericiguat initiation measure: Number of patients having hypotension or syncope in the entire 90 days after vericiguat initiation and by 30 days intervals sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Bayer city: Whippany state: New Jersey zip: 07981 country: United States lat: 40.82454 lon: -74.4171 hasResults: False
nctId: NCT06363084 id: IST-Nim-PC-6 briefTitle: A Retrospective Study for Nimotuzumab Plus Postoperative Adjuvant Chemotherapy for Resectable Pancreatic Cancer overallStatus: COMPLETED date: 2016-05-01 date: 2022-07-31 date: 2023-06-30 date: 2024-04-12 date: 2024-04-12 name: Ruijin Hospital class: OTHER briefSummary: This trial is a retrospective, observational study, patients who underwent surgical resection of the pancreas for non-metastatic pancreatic cancer between 2016 and 2022 were selected and divided into two groups according to with (study arm) or without (control arm) nimotuzumab. The primary efficacy endpoint was overall survival (OS). conditions: Resectable Pancreatic Cancer studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: RETROSPECTIVE count: 64 type: ACTUAL name: Nimotuzumab measure: overall survival (OS） measure: disease-free survival (DFS) measure: locoregional recurrence-free survival (LRRFS) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06363071 id: 202000495A3 briefTitle: APA and PAS Training for Gait Initiation in Parkinson's Disease overallStatus: RECRUITING date: 2022-06-13 date: 2025-03-31 date: 2025-05-31 date: 2024-04-12 date: 2024-04-12 name: Chang Gung University class: OTHER briefSummary: Our research focused on understanding the interplay between brain excitability and balance function in patients with Parkinson's disease (PD), alongside evaluating effective physical therapy methods. It highlights the prevalence of non-motor disorders and cognitive impairments among PD patients, including balance and postural issues, cognitive function decline, and gait instability. Additionally, it notes that PD patients exhibit abnormal electrophysiological responses, indicating altered central excitability. conditions: Parkinson Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 100 type: ESTIMATED name: Weight shift training and APA feedback name: Paired associative stimulation measure: Balance Performance measure: COP Path Length in Balance Tasks measure: COP Displacement in Balance Tasks measure: Motor Evoked Potentials (MEPs) measure: Intracortical Facilitation (ICF) measure: Intracortical Inhibition (ICI) measure: Walking Speed measure: Step Length measure: Step Time measure: COP Velocity in Balance Tasks measure: COP Area in Balance Tasks measure: Double Support Time measure: Single Support Time measure: Swing Time measure: Stance Time measure: Cadence sex: ALL minimumAge: 20 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Chang Gung University status: RECRUITING city: Taoyuan zip: 333 country: Taiwan name: Ya-Ju Chang, PhD role: CONTACT phone: 88632118800 phoneExt: 5515 email: yjchang@mail.cgu.edu.tw lat: 24.95233 lon: 121.20193 hasResults: False
nctId: NCT06363058 id: 201902166B0 briefTitle: Electrical Stimulation Cycling Training Effects on SCA overallStatus: RECRUITING date: 2022-04-08 date: 2025-07-31 date: 2025-07-31 date: 2024-04-12 date: 2024-04-17 name: Chang Gung University class: OTHER briefSummary: To focuses on the challenges faced by individuals with spinocerebellar ataxia (SCA), highlighting the major clinical sign of ataxia that affects their stability and ability to perform daily activities, thereby impacting their quality of life. It outlines the concept of neural plasticity, which is the brain's ability to adapt through changes in excitability, and notes that these changes are more enduring in the central nervous system (CNS) than in the peripheral nervous system (PNS). This adaptability, crucial for memory and motor learning, is compromised in SCA patients due to impaired brain areas and pathways. The summary further delves into motor learning, distinguishing between explicit and implicit learning, and points out that SCA patients exhibit deficiencies in procedural learning and cerebellar function. It also introduces the concept of priming as a preparatory mechanism that can enhance the effectiveness of physical therapy by modifying subsequent responses to stimuli. The document suggests that cycling, as an aerobic exercise, could prime the brain for improved blood flow and oxygenation, thereby supporting synaptic plasticity and the release of beneficial neurotrophic factors. Finally, the project aims to deepen the understanding of motor performance and learning mechanisms in SCA patients and apply these insights to clinical rehabilitation strategies. conditions: Spinocerebellar Ataxia (SCA) studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: CROSSOVER primaryPurpose: OTHER masking: NONE count: 145 type: ESTIMATED name: ES Cycling Training measure: Overall Response Time measure: Overall Error Rate measure: Motor Evoked Potentials (MEPs) measure: Intracortical Facilitation (ICF) measure: Intracortical Inhibition (ICI) measure: Total Scale for the Assessment and Rating of Ataxia (SARA) Score measure: Total Berg Balance Scale (BBS) Score measure: Total Time to Complete the Time Up and Go test (TUG test) measure: Walking Speed measure: Step Length measure: Step Time measure: Double Support Time measure: Single Support Time measure: Swing Time measure: Stance Time measure: Cadence sex: ALL minimumAge: 20 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Chang Gung University status: RECRUITING city: Taoyuan zip: 333 country: Taiwan name: Ya-Ju Chang, PhD role: CONTACT phone: 88632118800 phoneExt: 5515 email: yjchang@mail.cgu.edu.tw lat: 24.95233 lon: 121.20193 hasResults: False
nctId: NCT06363045 id: NIDEK-TONOREF-UK-0001 briefTitle: Comparative Study of the NIDEK TONOREF III With Predicate Devices overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-11 date: 2024-11 date: 2024-04-12 date: 2024-04-17 name: Nidek Co. LTD. class: INDUSTRY briefSummary: The primary objective of this clinical study is to prove that tonometry values for NIDEK TONOREF III are comparable to the predicate device and to prove that the pachymeter function of NIDEK TONOREF III is equivalent to the predicate device. The secondary objective is to demonstrate that the test device is as safe as the predicate devices. conditions: Intraocular Pressure studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 220 type: ESTIMATED name: NIDEK TONOREF III name: Haag-Streit, PERKINS HAND-HELD APPLANATION TONOMETER name: NIDEK CEM-530 measure: Equivalent to legally-marketed devices measure: Equivalent to the pachymeter function measure: The numbers of adverse events sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Aston University city: Birmingham zip: B4 7ET, UK country: United Kingdom lat: 52.48142 lon: -1.89983 hasResults: False
nctId: NCT06363032 id: 202110104RINB briefTitle: Elastography in Predicting Renal Outcome overallStatus: RECRUITING date: 2021-12-27 date: 2024-12-31 date: 2025-12-31 date: 2024-04-12 date: 2024-04-12 name: National Taiwan University Hospital class: OTHER briefSummary: There are two types of elastography: strain elastography assesses the degree of strain when applying a given amount of force to the skin. Shear-wave elastography assesses the velocity of shear wave propagation within the target lesion. A part of the tissue is deformed by a "push pulse", the velocity of the shear waves propagating within the tissue is detected, and the stiffness of the tissue is assessed based on the detected shear velocity. Shear-wave elastography has been intensively studied in thyroid, breast, liver, cervical lymph nodes, and musculoskeletal diseases with promising result.