hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06387927 id: PT-NEUR-10/2023-520 briefTitle: Effect of Home-exercise Programs Versus Supervised Core Stability Exercises on Hypertensive Patient With Low Back Pain overallStatus: COMPLETED date: 2023-09-02 date: 2024-02-02 date: 2024-02-20 date: 2024-04-29 date: 2024-04-29 name: Ahram Canadian University class: OTHER briefSummary: Thirty male and female hypertension patients with chronic mechanical non-specific low back pain were included in this randomized controlled study conducted at the Ababa Private Physical Therapy Center in Beni-Seuf, Egypt. They were randomly assigned into two equal groups; the study group A control (n = 15) had a supervised conventional core stability, while the study group B (n = 15) received a home exercise program. In both groups' patients had evaluations before and after their six-week course of therapy. Modified-modified Schober test was used to assess the active back range of motion (ROM), Arabic version of Oswestry disability index (ODI) was utilized to evaluate functional disability, and visual analog scale (VAS) was used to measure pain. conditions: Hypertension conditions: Low Back Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 30 type: ACTUAL name: home exercise program name: the core stability exercise measure: Assessment of pain measure: Assessment of lumbar flexion range of motion measure: Assessment of functional disability sex: ALL minimumAge: 30 Years maximumAge: 50 Years stdAges: ADULT facility: Faculty of physical therapy city: Giza zip: 3387722 country: Egypt lat: 30.00808 lon: 31.21093 hasResults: False
nctId: NCT06387914 id: PID 16707 id: 23/WM/0219 type: OTHER domain: Ethics Committee (South Birmingham REC) UK briefTitle: Efficacy of Pain Intervention With Deep Brain Stimulation Neuromodulation acronym: EPIONE overallStatus: NOT_YET_RECRUITING date: 2024-05-02 date: 2026-05-02 date: 2027-05-02 date: 2024-04-29 date: 2024-04-29 name: University of Oxford class: OTHER name: Jon MoultonTrust name: Placito Bequest name: Bioinduction briefSummary: The goal of this clinical trial is to learn if deep brain stimulation (DBS) works to treat severe pain following a stroke in adults. It will also learn about the safety of deep brain stimulation. The main questions it aims to answer are:
* Fill in questionnaires about pain and mood and have check ups remotely conditions: Central Post Stroke Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Double-blind trial, within subject randomisation and cross-over. primaryPurpose: TREATMENT masking: TRIPLE maskingDescription: Blinding maintained using the hand held controller (shows ON at all times) and programs which ensure equivalent battery drain at all stimulation settings.
Pseudo-ON =high frequency, low amplitude stimulation. Frequency up to 250 Hertz(Hz), Amplitude less than 0.5 milliamps(mA), Pulse Width 500 microseconds(uS). whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 30 type: ESTIMATED name: Stimulation ON name: Stimulation Pseudo-ON measure: McGill Pain Questionnaire V2.0 -Short Form - Present Pain Intensity (MQ-SF-PPI) score measure: Numerical Rating Scale (NRS) measure: McGill Pain Questionnaire V2.0 short form (MPQ-SF) McGill Pain Questionnaire V2.0 short form) MPQ-SF (McGill Pain Questionnaire V2.0 short form) measure: Brief Pain Inventory (BPI) - Short Form measure: Beck Depression Inventory (BDI II) measure: Patients' Global Impression of Change (PGIC) measure: EuroQol Quality of life (EQ5D-5L) measure: Healthy Days Measures (HDM) measure: Adverse Events (AEs) measure: Heart rate variability (HRV) measure: Client Service Receipt Inventory (CSRI) measure: MRI sex: ALL minimumAge: 21 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06387901 id: PABTOX - part 1 briefTitle: Investigating Paclitaxel Toxicity in Breast Cancer: The Roles of Physical Activity and Body Composition. acronym: PABTOX overallStatus: NOT_YET_RECRUITING date: 2024-05-06 date: 2025-05-06 date: 2025-10-31 date: 2024-04-29 date: 2024-04-29 name: Universitair Ziekenhuis Brussel class: OTHER name: Vrije Universiteit Brussel name: University Ghent briefSummary: This study looks into how a common breast cancer treatment, paclitaxel, can sometimes cause severe side effects that make it hard for patients to continue treatment. These side effects can significantly affect a patient's quality of life and even impact their recovery and overall health costs. What's interesting about this research is that it considers how a patient's lifestyle, specifically their physical activity levels and body makeup (like how much muscle and fat they have), might influence these side effects.
In simpler terms, this research is trying to find a way to make breast cancer treatment with paclitaxel safer and more comfortable by considering how a person's lifestyle and body type might affect their reaction to the drug. This could make a big difference in helping patients complete their treatment successfully and with a better quality of life. conditions: Breast Cancer conditions: Paclitaxel Adverse Reaction conditions: Chemotherapeutic Toxicity conditions: Chemotherapeutic Agent Toxicity conditions: Body Weight conditions: Physical Inactivity studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 40 type: ESTIMATED name: Paclitaxel Chemotherapy measure: Identification of Body Composition Parameter (Muscle mass) Related to Dose-Limiting Toxicities (DLTs) measure: Identification of Body Composition Parameters (Fat %) Related to Dose-Limiting Toxicities (DLTs) measure: Identification of Physical Activity Parameters Related to Dose-Limiting Toxicities (DLTs) measure: Paclitaxel Exposure Analysis (Cmax) measure: Paclitaxel Exposure Analysis (AUC) measure: Number and Type of Dose-Limiting Toxicities measure: Treatment-Related Adverse Events measure: Body Composition Measurement via Bioelectrical Impedance Analysis (BIA) (muscle mass) measure: Body Composition Measurement via Bioelectrical Impedance Analysis (BIA) (fat %) measure: Body Composition Measurement via Dual X-ray Absorptiometry (DEXA) (muscle mass) measure: Body Composition Measurement via Dual X-ray Absorptiometry (DEXA) (fat mass) measure: Body Composition Measurement via Dual X-ray Absorptiometry (DEXA) (extracellular fluid) measure: The European Organization for Research and Treatment of Cancer quality of life questionnaire (EORTC QLQ-C30) measure: EORTC QLQ-BR45 Breast (BR) Cancer Module measure: EORTC QLQ- Chemotherapy-Induced Peripheral Neuropathy (CIPN) 20 measure: European Health Interview Survey Physical Activity Questionnaire (EHIS PAQ) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Vrije Universiteit Brussel city: Brussel state: Jette zip: 1090 country: Belgium name: Nele Adriaenssens role: CONTACT phone: +32 2 476 36 23 email: Nele.Adriaenssens@vub.be name: Len De Nys role: CONTACT phone: +32 472 99 49 48 email: Len.de.nys@vub.be lat: 50.85045 lon: 4.34878 hasResults: False
nctId: NCT06387888 id: E-31034136-302.08.01-4221 briefTitle: The Effect of Mother's Voice on the Levels of Pain and Comfort in Newborns acronym: Newborn overallStatus: COMPLETED date: 2021-07-01 date: 2021-09-01 date: 2022-04-30 date: 2024-04-29 date: 2024-04-29 name: Istanbul Medipol University Hospital class: OTHER briefSummary: This study was conducted in a randomized controlled experimental type to determine the effect of maternal voice during care on pain and comfort level in term newborns receiving mechanical ventilation. The sample of the study was consisted of 60 term newborns receiving mechanical ventilation who were hospitalized in the 7-bed Neonatal Intensive Care Unit of a private hospital in Istanbul in accordance with the selection criteria. Introductory Information Form, Vital Signs Follow-up Form, Neonatal Comfort Behavior Scale and Neonatal Pain Scale (NPASS) forms prepared by the researchers were used as data collection tools. conditions: Newborns studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: INVESTIGATOR count: 60 type: ACTUAL name: Listening to mother's voice measure: Neonatal Comfort Behavior Scale measure: Neonatal Comfort Behavior Scale (COMFORTneo): sex: ALL minimumAge: 3 Weeks maximumAge: 41 Weeks stdAges: CHILD facility: Istanbul Medipol University Hospital city: Istanbul state: Beykoz country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06387875 id: Hangzhou Bay Cohort briefTitle: Cohort in Qianwan New District, Ningbo overallStatus: RECRUITING date: 2023-11-01 date: 2027-06-30 date: 2027-06-30 date: 2024-04-29 date: 2024-04-29 name: RenJi Hospital class: OTHER name: Ningbo Hangzhou Bay Hospital briefSummary: Our objective is to carry out research on prevention and control of noncommunicable chronic diseases, and establish a risk prediction mechanism for chronic diseases to promote early detection, early diagnosis and early treatment of chronic diseases in natural population in Qianwan District of Ningbo, significantly reduce medical costs and extend population life span. conditions: Cardiovascular Diseases conditions: Stroke conditions: Non-Communicable Chronic Diseases studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30000 type: ESTIMATED measure: death measure: incidence of cardio-cerebrovascular diseases measure: incidence of other non-communicable chronic diseases sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ren Ji Hospital Afflited to School of Medicine, Shanghai Jiao Tong University status: RECRUITING city: Shanghai country: China name: Jun Pu, MD,PHD role: CONTACT phone: 86-21-68383477 email: pujun310@hotmail.com lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06387862 id: 2022SIMBIOV briefTitle: Pharmacokinetics of Inhaled Levosimendan acronym: Symbiov overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2024-11 date: 2025-01 date: 2024-04-29 date: 2024-04-29 name: Universitair Ziekenhuis Brussel class: OTHER briefSummary: Determination of biological availability, time-to-peak and elimination half-life of inhaled levosimendan by administration of an inhaled- and intravenous dose of levosimendan. conditions: Left Ventricular Dysfunction studyType: INTERVENTIONAL phases: PHASE2 allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: BASIC_SCIENCE masking: NONE count: 6 type: ESTIMATED name: Levosimendan 2.5 milligram/milliliter Injectable Solutiondose Inhaled name: Levosimendan 2.5 milligram/milliliter Injectable Solutiondose Intravenous measure: Bioavailability of inhaled levosimendan measure: Time-to-peak of inhaled levosimendan measure: Elimination half-life of inhaled levosimenan measure: Effect of inhaled levosimendan on MAP measure: Effect of inhaled levosimendan on TVR measure: Effect of inhaled levosimendan on CO measure: Effect of inhaled levosimendan on LVOT VTI measure: Effect of inhaled levosimendan on FAC of the right vetricle measure: Effect of inhaled levosimendan on S' measure: Effect of inhaled levosimendan on SPAP sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: UZ Brussel city: Brussel zip: 1090 country: Belgium name: Matthias Raes, MD role: CONTACT phone: 024749872 email: matthias.raes@uzbrussel.be name: Marie-Claire Van Malderen, SC role: CONTACT phone: 024763110 email: marieclaire.vanmalderen@uzbrussel.be lat: 50.85045 lon: 4.34878 hasResults: False
nctId: NCT06387849 id: 03/2023 briefTitle: Aromatherapy Effect on Pain and Anxiety After C-section overallStatus: COMPLETED date: 2023-04-21 date: 2023-08-31 date: 2023-08-31 date: 2024-04-29 date: 2024-04-29 name: University Tunis El Manar class: OTHER briefSummary: A prospective randomized triple blinded study conducted in the obstetrics gynecology department of Ben Arous hospital over a period of four months and 10 days between April 2023 and August 2023.
The aim of this study was to evaluate the effectiveness of lavender aromatherapy on postoperative pain and anxiety after cesarean section under spinal anesthesia in Tunisian women. conditions: Post-operative Pain conditions: Post-operative Anxiety studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 100 type: ACTUAL name: Aromatherapy name: Placebo measure: Post-operative pain level measure: Post-operative anxiety level measure: Heart Rate (HR) measure: Systolic Blood Pressure (SBP) measure: Diastolic Blood Pressure (DBP) measure: Respiratory Rate (RR) measure: Pulsatile Oxygen Saturation sex: FEMALE minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Ben Arous Regional Hospital city: Ben Arous country: Tunisia lat: 36.75306 lon: 10.21889 hasResults: False
nctId: NCT06387836 id: B2024-063 briefTitle: LINC01844 as a Diagnostic Biomarker for POCD in Elderly Patients overallStatus: RECRUITING date: 2024-02-21 date: 2025-02-21 date: 2025-06-30 date: 2024-04-29 date: 2024-04-29 name: Shanghai Zhongshan Hospital class: OTHER briefSummary: Postoperative cognitive dysfunction (POCD) is a common complication after surgery that is associated with more adverse events and death. The goal of this observational study is to learn about the diagnosis performance of long intergenic non-coding RNA(LINC01844) level in blood of older people for POCD. The main question it aims to answer is:
Does the relative level of LINC01844 in blood help diagnose POCD of older people after surgery? Participants undergoing elective lumbar decompression and fusion will finish neuropsychological evaluations one day before and 1st, 3rd and 5th day after surgery. At the same timepoint, the relative level of LINC01844 in blood will also be tested. conditions: Postoperative Cognitive Dysfunction studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 63 type: ESTIMATED measure: relative level of LINC01844 measure: serum reactive protein-C measure: serum interleukin-6 sex: ALL minimumAge: 65 Years maximumAge: 85 Years stdAges: OLDER_ADULT facility: Zhongshan Hospital Fudan University status: RECRUITING city: Shanghai state: Shanghai zip: 200032 country: China name: Danfeng Jin, M.D. role: CONTACT phone: +8613795306154 email: jindanfeng0506@163.com name: Shengjin Ge, Ph.D. role: CONTACT phone: +8613601926171 email: ge.shengjin@zs-hospital.sh.cn name: Shengjin Ge, Ph.D. role: PRINCIPAL_INVESTIGATOR lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06387823 id: K5321 briefTitle: Efficacy and Safety of Sivelestat Sodium and Dexamethasone in the Treatment of ARDS acronym: STAR overallStatus: NOT_YET_RECRUITING date: 2024-04-27 date: 2025-06-01 date: 2025-09-01 date: 2024-04-29 date: 2024-04-29 name: Peking Union Medical College Hospital class: OTHER name: Peking University name: Shanghai Huilun Pharmaceutical Co., Ltd. briefSummary: The goal of this clinical trial is to evaluate the efficacy and safety of Sivelestat sodium and dexamethasone in the treatment of patients with moderate to severe ARDS. The main questions it aims to answer are:
* Is dexamethasone more effective in the treatment of patients with moderate to severe ARDS compared with placebo? Participants will receive Sivelestat sodium, dexamethasone or placebo. Researchers will compare the efficacy and safety of Sivelestat sodium, dexamethasone and placebo. conditions: Acute Respiratory Distress Syndrome studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 300 type: ESTIMATED name: Sivelestat sodium name: Dexamethasone name: Sivelestat sodium placebo name: Dexamethasone placebo measure: 28-day ventilator-free days measure: Informed consent rate measure: Recruitment rate measure: Recruitment compliance rate measure: Protocol adherence rate measure: Completion of follow-up visits measure: 28-day mortality measure: 90-day mortality measure: 28-day length of stay measure: 28-day organ support free day measure: Sequential organ failure assessment (SOFA) measure: Murray's acute lung injury score measure: C-reactive protein (CRP) measure: Interleukin-6 (IL-6) measure: Interleukin-8 (IL-8) measure: Procalcitonin (PCT) measure: Neutrophil-to-lymphocyte Ratio (NLR) measure: Neutrophil elastase measure: New-onset infection rate measure: Re-intubation rate measure: Adverse event sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06387810 id: MA-PC-II-010 briefTitle: Irinotecan Liposome II in Combination With 5-FU/LV and Oxaliplatin in Perioperative Treatment of Borderline Resectable Pancreatic Cancer acronym: undetermined overallStatus: NOT_YET_RECRUITING date: 2024-04-17 date: 2026-04-30 date: 2026-06-30 date: 2024-04-29 date: 2024-04-29 name: Peking Union Medical College Hospital class: OTHER briefSummary: This is a prospective, single-arm, phase II study to evaluate the efficacy and safety of irinotecan liposome II in combination with oxaliplatin and 5-FU/LV in perioperative treatment of borderline resectable pancreatic cancer in 45 patients. conditions: Borderline Resectable Pancreatic Cancer studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 45 type: ESTIMATED name: irinotecan liposome II combined with 5-FU/LV and oxaliplatin measure: event free survival measure: overall survival measure: R0 resection rate measure: R1 excision rate measure: adverse event sex: ALL minimumAge: 18 Years maximumAge: 110 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06387797 id: UNLV-2023-321 briefTitle: Primary and Secondary Prevention of Type 2 Diabetes Mellitus in Clark County overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-05-30 date: 2025-05-31 date: 2024-04-29 date: 2024-04-29 name: University of Nevada, Las Vegas class: OTHER name: University of Nevada, Reno briefSummary: This pilot and feasibility study aims to assess the effectiveness of a nutrition education intervention using the Cooking Matters for Adults Curriculum (SNAP-Ed). The study compares this standard curriculum with an enhanced version that includes the same curriculum but has additional components, incorporating specific information related to type 2 diabetes. Additionally, participants in the enhanced group will receive continuous glucose monitors to wear during the study for 10 days. The primary outcomes of the study include evaluating the acceptability of the intervention, and the feasibility of conducting the intervention at the UNLV Nutrition Center. The investigators will also assess participants' Knowledge, Attitudes, and Intentions regarding produce consumption. Alongside feasibility and acceptability, the study aims to explore the preliminary effectiveness of the intervention in increasing fruit and vegetable consumption, reducing HbA1c, managing cardiometabolic risk, and improving gut microbiome composition and diversity among participants in the program. The investigators will also assess changes in other lifestyle behaviors from baseline to post-intervention (6 weeks) (sleep, stress, physical activity, and sedentary behavior). conditions: At Risk for Type 2 Diabetes Mellitus conditions: Pre Diabetes studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Participants will be randomized to one of two parallel study arms.
2. CMA + Enhanced cooking classes with added components comprising cooking practices specific to diabetes prevention, online information as well as short assignments and activities regarding sleep, stress, physical activity, and sedentary behaviors. The CMA+ arm will also have the opportunity to use a continuous glucose monitor (CGM) for 10 days immediately following the baseline assessment visit. This will be an optional component and participants will not be excluded if they do not wish to use the CGM. (6 weeks) primaryPurpose: PREVENTION masking: SINGLE maskingDescription: Because of the parallel arm differences, it would not be possible to mask the arm assignment for the participant or investigator. However, we will mask the arm assignment for the outcomes assessor, in particular for the HbA1c% assessment. whoMasked: OUTCOMES_ASSESSOR count: 120 type: ESTIMATED name: Cooking Matters for Adults (CMA+) name: Cooking Matters for Adults (CMA) measure: Feasibility of conducting the intervention measure: Acceptability of the intervention measure: Acceptability of each cooking class measure: Knowledge about the importance of produce consumption measure: Attitudes toward produce consumption measure: Intentions to consume recommended amounts of produce during and after intervention measure: Changes in fruit and vegetable consumption in servings per day measure: HbA1c% measure: Body weight in kg measure: Gut Microbiota composition measure: waist circumference in cm measure: body fat percentage (%) measure: non fat mass in kg measure: blood pressure in mmHg measure: fasting blood glucose in mg/dL measure: fasting total cholesterol in mg/dL measure: fasting LDL cholesterol in mg/dL measure: fasting HDL cholesterol in mg/dL measure: fasting triglyceride level in mg/dL measure: Usual dietary quality measure: Week 6 dietary quality measure: physical activity energy expenditure average kcals per day measure: Time spent in sedentary behavior in minutes per day measure: physical activity intensity distribution as minutes per day and average percentage of day measure: sleep quantity in hours per day measure: sleep quality measure: stress levels measure: Nutrition Security sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Nevada, Las Vegas city: Las Vegas state: Nevada zip: 89154 country: United States name: Sara K Rosenkranz, PhD role: CONTACT phone: 702-895-0938 email: Sara.Rosenkranz@unlv.edu name: Richard Rosenkranz, PhD role: CONTACT phone: 702-895-5198 email: Richard.Rosenkranz@unlv.edu name: Keren Morales, B.S., RD role: SUB_INVESTIGATOR name: Donya Shahamati, B.S. role: SUB_INVESTIGATOR name: Laura Kruskall, PhD, RD role: SUB_INVESTIGATOR name: Elika Nematian, M.S. role: SUB_INVESTIGATOR lat: 36.17497 lon: -115.13722 hasResults: False