hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06311279 id: Soh-Med-24-03-01MD briefTitle: End to End Versus Side to End Anastomosis After Anterior Resection of Cancer Rectum overallStatus: RECRUITING date: 2024-03-05 date: 2025-01-01 date: 2025-03-20 date: 2024-03-15 date: 2024-03-15 name: Sohag University class: OTHER briefSummary: Comparison between end to end and side to end anastomosis after anterior resection of cancer rectum and compare the outcomes of both surgical techniques. The main outcomes were bowel functional outcomes and QoL. Bowel functional outcomes mainly included three indexes: stool frequency, urgency, incomplete defecation, and incontinence. The secondary outcomes were surgical outcomes including operative time, postoperative hospital stay, postoperative complications, reoperation, and mortality. conditions: Rectum Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SINGLE_GROUP interventionModelDescription: Comparison between end to end and side to end anastomosis after anterior resection of cancer rectum and compare the outcomes of both surgical techniques. The main outcomes were bowel functional outcomes and QoL. Bowel functional outcomes mainly included three indexes: stool frequency, urgency, incomplete defecation, and incontinence. The secondary outcomes were surgical outcomes including operative time, postoperative hospital stay, postoperative complications, reoperation, and mortality primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: randomized comparative clinical trial whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 20 type: ESTIMATED name: Anterior resection of Rectal cancer measure: Operative time measure: Anastomotic leakage measure: hospital stay measure: Mortality measure: Anastomotic leak amount sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sohag university status: RECRUITING city: Sohag zip: 82511 country: Egypt name: Nabil A Al-Ameer, MD role: CONTACT phone: 1118416290 email: Nabil.abdelnaser@med.sohag.edu.eg name: Ahmed G Hassanein, MD role: CONTACT phone: 1552538300 phoneExt: 0020 email: ethics@med.sohag.edu.eg lat: 26.55695 lon: 31.69478 hasResults: False
nctId: NCT06311266 id: 34-424 ex 21/22 briefTitle: Robotic Endoscopic Neurosurgical Interventions acronym: RENI overallStatus: NOT_YET_RECRUITING date: 2024-03-30 date: 2025-03 date: 2025-10 date: 2024-03-15 date: 2024-03-15 name: Medical University of Graz class: OTHER briefSummary: Endoscopic operations have become increasingly important in the field of neurosurgery over the past decade and require a high degree of precision. Current methods for setting the planned trajectory only offer limited precision due to the manual control, which can lead to complications.
The investigators therefore expect not only an increase in the accuracy of endoscopic interventions, but also a reduction in morbidity. conditions: Robot for Endoscopic Neurosurgical Interventions studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: prospective, randomized, single center cohort trial primaryPurpose: DEVICE_FEASIBILITY masking: SINGLE maskingDescription: Due to the surgical workflow (using the robotic guided device or not) the performing surgical team will not be blinded to the allocated group. However, investigators will be blinded to the allocation of the patients. whoMasked: PARTICIPANT count: 19 type: ESTIMATED name: Robotic endoscopic neurosurgical intervention measure: Target Error (TE) measure: Adverse Effect sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06311253 id: 2024-LACTOFERRINPREGNANT briefTitle: Non-surgical Periodontal Treatment With Adjunctive Use of Lactoferrin Contained in Toothpaste and Mouthwash overallStatus: ENROLLING_BY_INVITATION date: 2024-03-20 date: 2024-11 date: 2024-11 date: 2024-03-15 date: 2024-04-26 name: University of Pavia class: OTHER briefSummary: The aim of the study is to assess the effect of lactoferrin in LBC complex can be effective in reducing periodontal clinical parameters in a 6-month study on pregnant patients. conditions: Periodontal Diseases studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: Emoform Glic Toothpaste name: Emoform Glic Mouthwash measure: Change in Recession (R) measure: Change in Plaque Index (Silness and Loe, 1964) measure: Change in Bleeding on Probing (BoP) measure: Change in Probing Pocket Depth (PPD) measure: Change in modified Marginal Gingival Index (mMGI) measure: Change in Papillary Marginal Gingival Index (PMGI) measure: Change in Plaque Control Record (PCR%) measure: Change in Clinical Attachment Loss (CAL) sex: ALL minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: Unit of Dental Hygiene - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Paediatrics - University of Pavia city: Pavia state: Lombardy zip: 27100 country: Italy lat: 45.19205 lon: 9.15917 hasResults: False
nctId: NCT06311240 id: 02-24-108-003 briefTitle: Chronic Pain in Patients in Hemodialysis acronym: DolERC overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-06 date: 2024-09 date: 2024-03-15 date: 2024-03-15 name: Cardenal Herrera University class: OTHER name: Consorci Sanitari de Terrassa briefSummary: Pain is one of the most common symptoms among patients with End Stage Renal Disease (ESRD), and often goes unrecognized or inadequately managed in hemodialysis patients. More than 50% of patients undergoing hemodialysis suffer from pain, with 75% of them being treated ineffectively due to healthcare professionals\&#39; lack of awareness of this symptom. Therefore, pain management in this population is a complex and challenging task for healthcare providers. The most prevalent pain syndromes in hemodialysis patients include musculoskeletal disorders, metabolic neuropathies, in addition to typical intradialytic pain.
The aim of this study is to assess the presence and characteristics of chronic pain in patients with ESRD undergoing hemodialysis to determine whether it is relevant to include the management of chronic pain in the holistic treatment (physical activity, nutrition, and psychological support) already being implemented in various studies for these patients. conditions: Chronic Pain conditions: Chronic Kidney Disease studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 40 type: ESTIMATED measure: Stress level assessed by the salivary cortisol test measure: Stress level assessed by the perceived stress scale (PSS) measure: Self- efficacy assessed by questionnaire measure: Quality of sleep assessed by Pittsburgh Sleep Quality Index measure: The impact of headaches on life assessed by Headache Impact Test-6 measure: Anxiety and depression assessed by Hospital anxiety and depression scale (HADS) measure: Aspects of catastrophic cognitions about pain-rumination, magnification, and helplessness assessed by The Pain Catastrophizing Scale (PCS) measure: Chronic pain assessd by Chronic Pain Grade Questionnaire sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Consorci Sanitari de Terrassa city: Terrassa state: Barcelona zip: 08227 country: Spain name: Vicent Esteve-Simó, PhD role: CONTACT phone: 00 34 937310007 email: vesteve@cst.cat lat: 41.56667 lon: 2.01667 facility: Universidad Cardenal Herrera-CEU, CEU Universities city: Alfara del Patriarca state: Valencia zip: 46115 country: Spain name: Eva Segura Orti, PhD role: CONTACT phone: 0034961369000 phoneExt: 64439 email: ESEGURA@UCHCEU.ES lat: 39.55 lon: -0.38333 hasResults: False
nctId: NCT06311227 id: NCI-2024-01904 id: NCI-2024-01904 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: 10637 type: OTHER domain: National Cancer Institute LAO id: 10637 type: OTHER domain: CTEP briefTitle: Venetoclax for the Treatment of Patients With Relapsed Hairy Cell Leukemia overallStatus: NOT_YET_RECRUITING date: 2024-05-20 date: 2025-07-01 date: 2025-07-01 date: 2024-03-15 date: 2024-03-15 name: National Cancer Institute (NCI) class: NIH briefSummary: This phase II trial tests how well venetoclax works in treating patients with hairy cell leukemia that has come back after a period of improvement (relapsed). Venetoclax is in a class of medications called B-cell lymphoma-2 (BCL-2) inhibitors. It may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. conditions: Recurrent Hairy Cell Leukemia conditions: Recurrent Hairy Cell Leukemia Variant studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 20 type: ESTIMATED name: Biospecimen Collection name: Bone Marrow Aspiration name: Bone Marrow Biopsy name: Computed Tomography name: Magnetic Resonance Imaging name: Venetoclax measure: Objective response rate measure: Complete remission (CR) rate measure: Minimal residual disease (MRD)-negative CR rate measure: MRD negativilty measure: Incidence of adverse events measure: Complete response duration measure: MRD-negative survival measure: TP53 mutations and other mutations measure: Whole exome sequencing of relapsed HCL/HCLv samples sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06311201 id: P.T.REC/012/004256 briefTitle: Effect of Pilates Exercises on Diastasis Recti Abdominis in Postpartum Women overallStatus: COMPLETED date: 2023-09-26 date: 2024-01-26 date: 2024-01-26 date: 2024-03-15 date: 2024-03-19 name: Cairo University class: OTHER briefSummary: The purpose of the study was to investigate the effect of Pilates exercises on diastasis recti abdominis in postpartum women. conditions: Diastasis Recti studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: INVESTIGATOR count: 50 type: ACTUAL name: Abdominal belt name: Pilates exercises measure: Measurement of separation between the two-rectus abdominis muscles above the umbilicus at rest measure: Measurement of separation between the two-rectus abdominis muscles above the umbilicus during contraction measure: Measurement of separation between the two-rectus abdominis muscles at level of the umbilicus at rest measure: Measurement of separation between the two-rectus abdominis muscles at level of the umbilicus during contraction measure: Measurement of separation between the two-rectus abdominis muscles below the umbilicus at rest measure: Measurement of separation between the two-rectus abdominis muscles below the umbilicus during contraction measure: Assessment of trunk flexion strength measure: Assessment of static trunk flexion endurance measure: Assessment of functional status sex: FEMALE minimumAge: 20 Years maximumAge: 35 Years stdAges: ADULT facility: Cairo University city: Giza country: Egypt lat: 30.00808 lon: 31.21093 hasResults: False
nctId: NCT06311188 id: HUM00240243 id: 1R21MD016940-01A1 type: NIH link: https://reporter.nih.gov/quickSearch/1R21MD016940-01A1 briefTitle: Exploring PTSD Symptoms, Barriers and Facilitators to Mindfulness overallStatus: NOT_YET_RECRUITING date: 2024-04-14 date: 2024-11-30 date: 2025-01-31 date: 2024-03-15 date: 2024-03-25 name: University of Michigan class: OTHER name: National Institute on Minority Health and Health Disparities (NIMHD) briefSummary: The purpose of this study is to investigate justice-involved Black/African American female adolescents' (JI BAFAs; N=35) self-reported outcomes: stress, posttraumatic stress disorder (PTSD), recidivism, etc., as well as their parents/caregivers' (P/Cs; N=35) stress and pre- and post- intervention results along with their views of an adapted intervention. conditions: Stress conditions: Trauma conditions: PTSD conditions: HPA studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Single arm trial primaryPurpose: TREATMENT masking: NONE count: 90 type: ESTIMATED name: ITR Healing intervention measure: PTSD Screen measure: PTSD Checklist measure: Stress Psychosocial measure: Stress Physiological measure: Parent/Caregiver-Child Relationship measure: Five Facet Mindfulness Questionnaire (FFMQ) measure: Recidivism measure: Personal Agency measure: Racial Identity measure: Parenting Stress measure: MoCA screen measure: CESD - Depression screen sex: ALL minimumAge: 14 Years maximumAge: 90 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06311175 id: H20-0114 briefTitle: Diet Tracking Prescriptions for Weight Loss overallStatus: RECRUITING date: 2024-04-30 date: 2024-05-31 date: 2024-09-01 date: 2024-03-15 date: 2024-04-25 name: University of Connecticut class: OTHER briefSummary: Lifestyle interventions are effective at producing modest weight loss. One of the strongest predictors of weight loss is food tracking, which involves logging all food and beverage consumed each day in an effort to stay within a daily calorie goal. Standard lifestyle interventions prescribe daily food tracking for the length of the program which can range from 3-24 months. This can be a taxing prescription that is not feasible to do long term for many people. The purpose of this pilot feasibility randomized trial is to test the feasibility of 3 tracking prescriptions during an 8 week digital weight loss intervention: 1) tracking daily, 2) tracking two weeks on and one week off, 3) tracking every other week. Feasibility is defined as tracking prescription compliance, burden, acceptability, and perceived efficacy, and tracking self-efficacy. Diet tracking will be evaluated one month after the intervention ends so that groups can be compared on diet tracking maintenance. conditions: Obesity studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Participants will be randomly assigned to one of three intervention groups in parallel for the duration of the study primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 108 type: ESTIMATED name: Dietary Tracking Prescription measure: Compliance with diet tracking prescription measure: Persistence with diet tracking prescription measure: Burden of tracking prescription measure: Acceptability of tracking prescription measure: Perceived efficacy of tracking prescription measure: Self-efficacy of diet tracking measure: Diet Tracking One Month Post-Intervention sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Connecticut status: RECRUITING city: Storrs state: Connecticut zip: 06269 country: United States name: Sherry Pagoto, PhD role: CONTACT phone: 860-486-2313 email: sherry.pagoto@uconn.edu name: Sherry Pagoto, PhD role: PRINCIPAL_INVESTIGATOR lat: 41.80843 lon: -72.24952 typeAbbrev: Prot hasProtocol: True hasSap: False hasIcf: False label: Study Protocol date: 2023-09-14 uploadDate: 2024-01-03T11:42 filename: Prot_000.pdf size: 518051 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2023-09-14 uploadDate: 2024-03-12T13:35 filename: ICF_001.pdf size: 296855 hasResults: False
nctId: NCT06311162 id: 2023-01615 briefTitle: Early Life Intervention in Pediatrics Supported by E-health - SMOKE acronym: ELIPSE-II overallStatus: NOT_YET_RECRUITING date: 2024-03-31 date: 2027-08-31 date: 2028-07-31 date: 2024-03-15 date: 2024-03-20 name: Insel Gruppe AG, University Hospital Bern class: OTHER name: University of Bern briefSummary: Unrestricted parental smoking habits are lifestyle risk behaviors associated with chronic, systemic inflammation, which promotes the pathogenesis of non-communicable diseases (NCDs). Exposure to secondhand tobacco smoke in early life contributes to the development of specific NCDs in children, i.e. asthma. Early preventive measures to improve lifestyle behavior in parents are therefore of utmost importance. The aim of ELIPSE-II is to assess whether an eHealth application intervention for parents is feasible and efficacious in lowering levels of urinary cotinine as a measure of second-hand smoke exposure in their children . conditions: Smoking Reduction conditions: Asthma in Children conditions: Wheezing conditions: Non-Communicable Disease conditions: Life Style conditions: Behavior, Smoking studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Single-blind randomized controlled parallel-group clinical trial primaryPurpose: PREVENTION masking: DOUBLE maskingDescription: The study team members who are conducting assessments on the participants remain blinded to the treatment allocation. whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 160 type: ESTIMATED name: Life-Style app name: Sham Comparator measure: Change from baseline in urinary levels of cotinine in children measure: Change from baseline in urinary levels of cotinine in children measure: Change from baseline in protective measures taken by parents to protect children from second-hand smoke exposure measure: Acceptance and usability of the app (parent reported outcome) measure: Acceptance of the app measure: Usability of the app measure: Number of episodes of airway disease in children measure: Frequency of inhalant medications or antibiotics required for airway disease in children measure: Amount of inhalant medications or antibiotics required for airway disease in children measure: Number of episodes of severe airway disease in children requiring hospitalization measure: Change from baseline in parental smoking intensity (number of cigarettes smoked per day) sex: ALL maximumAge: 5 Years stdAges: CHILD facility: Department of Paediatrics, Inselspital, Bern University Hospital city: Bern zip: 3010 country: Switzerland name: Julian Jakob, MD role: CONTACT phone: +41 31 632 12 93 email: julian.jakob@insel.ch name: Matthias V. Kopp, Prof, MD role: CONTACT phone: +41 31 66 4 13 51 email: matthias.kopp@insel.ch name: Julian Jakob, MD role: SUB_INVESTIGATOR name: Andrea Wyssen, PhD role: SUB_INVESTIGATOR lat: 46.94809 lon: 7.44744 hasResults: False
nctId: NCT06311149 id: 479/2023/Oss/AOUFe briefTitle: Multicenter Evaluation of Patients Using LATITUDE Monitoring System acronym: Multitude overallStatus: RECRUITING date: 2023-12-01 date: 2043-12-31 date: 2043-12-31 date: 2024-03-15 date: 2024-03-15 name: University Hospital of Ferrara class: OTHER briefSummary: The Multitude is a registry of patients who receive commercially available CIEDs that remotely communicate through the LATITUDE monitoring system and transfer data to a central database.
The Multitude study will facilitate the sharing of scientific proposals within a large network of researchers, and it will allow researchers to record the experience with medical devices throughout the device and patient lifecycle. conditions: Cardiovascular Diseases conditions: Arrhythmias, Cardiac conditions: Heart Failure conditions: Sudden Cardiac Death studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 20000 type: ESTIMATED measure: Mortality measure: Hospitalization measure: Device therapy measure: Device-related complications sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Azienda Ospedaliero-Universitaria di Ferrara status: RECRUITING city: Ferrara zip: 44124 country: Italy name: Matteo Bertini, MD, PhD role: CONTACT email: brtmtt2@unife.it lat: 44.83804 lon: 11.62057 facility: Policlinico Federico II status: RECRUITING city: Napoli country: Italy name: Antonio Rapacciuolo role: CONTACT email: antonio.rapacciuolo@unina.it lat: 40.85216 lon: 14.26811 hasResults: False
nctId: NCT06311136 id: PEAK briefTitle: Effectiveness of an Ecological Momentary Emotion Regulation Intervention overallStatus: RECRUITING date: 2024-01-12 date: 2024-12 date: 2024-12 date: 2024-03-15 date: 2024-03-18 name: Heidelberg University class: OTHER briefSummary: This two-armed randomized controlled trial aims to investigate the effectiveness of an emotion regulation intervention in individuals with and without depressive disorders. The study encompasses participants diagnosed with mild to moderate major depression or persistent depressive disorder and healthy controls without a current depressive disorder.
A second aim of the study is to compare beliefs about positive emotions and strategies to regulate them between individuals with and without current depressive disorders. Furthermore, the investigators aim to examine why individuals might choose unfavorable emotion regulation strategies even when feeling good. Therefore, another research question is, how emotion beliefs might explain emotion regulation strategy choice. conditions: Depressive Disorder, Major conditions: Persistent Depressive Disorder conditions: Healthy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized Controlled Trial with an Intervention Group and a Control Group without an intervention. primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: During the treatment phase, both the intervention and monitoring-only control groups use a diary called "Positive Everyday Affect Knowledge". Participants are informed that the diary entries may include instructions for implementing specific emotion regulation strategies in their daily activities. However, this component of the procedure is not characterized explicitly as an intervention. This methodological consideration ensures that differences observed between the groups can be attributed to the intervention itself, rather than to differences in participants' expectations.
Clinical interviews will be conducted blindly. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 200 type: ESTIMATED name: Valence-Specific Ecological Momentary Intervention measure: Emotion Regulation Ability (Positive, Negative Emotions) measure: Emotion Regulation Self-Efficacy for Positive and Negative Emotions measure: Emotion Regulation Strategy Use in Positive and Negative Emotional Contexts measure: Depressive Symptoms measure: Positive and Negative Affect measure: Emotion Beliefs (Controllability, Usefulness) about Positive and Negative Emotions measure: Well-being measure: Life Satisfaction measure: Emotion Beliefs about Positive Emotions (Delay Happiness, Living in the Moment) measure: Emotion Beliefs about Positive Emotions (Fear of Happiness) measure: Negative Emotional Contrast Avoidance measure: Emotion Regulation Strategy Use measure: Self-Esteem measure: Locus of Control measure: Controllability Beliefs about Emotions measure: Anxiety Symptoms sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Clinical Psychology and Psychotherapy, Institute of Psychology, Heidelberg University status: RECRUITING city: Heidelberg zip: 69117 country: Germany name: Ilka Mueller, M.Sc. role: CONTACT phone: +496221/547362 email: ilka.mueller@psychologie.uni-heidelberg.de name: Luise Pruessner, M.Sc. role: CONTACT phone: +496221/547282 email: luise.pruessner@psychologie.uni-heidelberg.de lat: 49.40768 lon: 8.69079 hasResults: False
nctId: NCT06311123 id: ISR IM047-059 briefTitle: Understanding Ozanimod's MOA Via Mass Cytometry in Ulcerative Colitis overallStatus: RECRUITING date: 2023-10-06 date: 2026-09-30 date: 2026-09-30 date: 2024-03-15 date: 2024-03-15 name: University of California, San Diego class: OTHER briefSummary: The goal of this observational study is to learn about the mechanism of action of ozanimod in patients with ulcerative colitis (UC). The main questions it aims to answer are: