hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06358326 id: Karabuk-1 briefTitle: Dry Needling and Rehabilitatin Carpal Tunnel Syndrome overallStatus: RECRUITING date: 2024-04-05 date: 2024-08-30 date: 2024-09-30 date: 2024-04-10 date: 2024-04-10 name: Karabuk University class: OTHER briefSummary: Dry needling is used for myofascial release. However, its effectiveness in carpal tunnel syndrome (CTS) is not well known. It is thought that dry needling may also be an effective treatment for CTS by providing relaxation in the fascial tissue. Therefore, this study will examine the effects of dry needling treatment on pain, function, range of motion, proprioception and disability in patients with CTS. conditions: Dry Needling conditions: Carpal Tunnel Syndrome conditions: Myofacial Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Parallel Assignment primaryPurpose: TREATMENT masking: TRIPLE maskingDescription: Triple-blind study; the patients will not be informed about their groups (training group or the control group) and they will be evaluated and trained at different places and times. whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Dry needling name: Control group measure: Pain severity measure: Wrist range of motion measure: Position sense measure: Severity of symptoms measure: Functional status measure: Hands activity level measure: neuropathic pain severity measure: Nerve cross-sectional area sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Pursaklar State Hospital status: RECRUITING city: Ankara country: Turkey name: Fidan Yılmaz, Msc role: CONTACT phone: 0551 207 2954 email: fdnylmz07@gmail.com lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06358300 id: Usakpcos2 briefTitle: Visceral Adiposity Index Differences Between Subtypes of Polycystic Ovary Syndrome overallStatus: COMPLETED date: 2022-01-01 date: 2022-09-01 date: 2023-07-20 date: 2024-04-10 date: 2024-04-10 name: Uşak University class: OTHER briefSummary: We aimed to investigate visceral adiposity index (VAI) in patients with different phenotype of policystic ovary syndrome (PCOS) and to compare healthy controls. conditions: Visceral Adiposity Index conditions: Polycystic Ovary Syndrome studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 300 type: ACTUAL measure: Visceral Adiposity Index Differences Between Subtypes of Polycystic Ovary Syndrome sex: FEMALE minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: Usak Training and Research Hospital city: Usak zip: 64100 country: Turkey lat: 38.67351 lon: 29.4058 hasResults: False
nctId: NCT06358287 id: STUDY19030375 briefTitle: Neural Correlates of Auriculotherapy overallStatus: COMPLETED date: 2021-07-15 date: 2022-11-07 date: 2022-11-07 date: 2024-04-10 date: 2024-04-10 name: Keith M. Vogt, MD, PhD class: OTHER briefSummary: Chronic pain continues to be a major health issue, creating a significant societal burden, as it is an independent risk factor for opioid use disorder (OUD) and deaths. Acute pain episodes can often engender OUD due to lack of effective strategies to treat pain and prevent the transition to chronic pain. One potential non-opioid method for pain relief is auriculotherapy (AT), where acupuncture-like treatment is administered to the ear. The objective of this pilot study is to illustrate that AT-related brain effects can be found using functional connectivity MRI (fcMRI) in patients with low back pain. conditions: Chronic Pain studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 10 type: ACTUAL name: cryogenic auriculotherapy measure: Default Mode Network (DMN)-to-Anterior Cingulate Cortex (ACC) connectivity measure: Brief Pain Inventory (BPI) Severity Scores MRI #1 measure: BPI Pain Severity Scores MRI #2 measure: General Anxiety Disorder-7 (GAD-7) Scoring sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: UPMC Montefiore city: Pittsburgh state: Pennsylvania zip: 15213 country: United States lat: 40.44062 lon: -79.99589 hasResults: False
nctId: NCT06358274 id: MED-2024-32848 briefTitle: Nutritional and Metabolic Dynamics of Thru-Hiking: A Longitudinal Study on the Colorado Trail overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-07-01 date: 2024-07-01 date: 2024-04-10 date: 2024-04-10 name: University of Minnesota class: OTHER briefSummary: Thru-hiking the Colorado Trail presents distinct challenges owing to its diverse landscapes and high altitudes. The study aims to delve into the physiological and nutritional facets of extended wilderness trekking among thru-hikers. Activities encompass participant recruitment from the Colorado Trail Foundation community, baseline and post-trail assessments including blood lipid panel analysis and anthropometric measurements, data collection during the trail period involving recording daily mileage, exertion levels, and dietary intake, rigorous statistical analysis to explore correlations among various parameters, and adherence to ethical considerations including obtaining formal approval and ensuring informed consent procedures are followed to safeguard participants' rights and privacy. Through this endeavor, the study seeks to offer insights into the metabolic responses and cardiovascular implications associated with thru-hiking, shedding light on the interplay between diet, lifestyle factors, and metabolic health in challenging environments.
The specific aims include examining the metabolic responses and cardiovascular implications associated with thru-hiking, exploring correlations between dietary intake and blood lipid profiles, and elucidating the interplay between lifestyle factors and metabolic health in demanding environments. This study is not limited to program evaluation, quality assurance, or improvement activities within a specific department or setting but rather seeks to contribute to scientific knowledge and inform evidence-based recommendations for individuals engaging in thru-hiking or similar high-intensity activities. conditions: Thru-hiking studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30 type: ESTIMATED name: Thru-hiking measure: blood lipid panel: total cholesterol measure: blood lipid panel: high-density lipoprotein (HDL) measure: blood lipid panel: low-density lipoprotein (LDL) measure: blood lipid panel: triglycerides sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06358261 id: IRB00433279 id: R03DK135898 type: NIH link: https://reporter.nih.gov/quickSearch/R03DK135898 briefTitle: Study of a Diabetes Prevention Patient Activation Clinical Decision Support Tool overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-09 date: 2025-09 date: 2024-04-10 date: 2024-04-23 name: Johns Hopkins University class: OTHER name: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) briefSummary: The investigators overarching goal is to increase the percentage of patients engaging in diabetes prevention activities to reduce the incidence of diabetes. The investigators objective is to design and pilot test a prediabetes clinical decision support (CDS) tool in the electronic health record (EHR) that will assess the patient's activation level based on responses to a questionnaire. Based on the patient's assessed level of activation, the tool will generate several communication recommendations to guide clinicians in conversations related to prediabetes/lifestyle change and tailor recommendations about available resources (e.g., care manager, health coach, DPP) to support patient activation. conditions: PreDiabetes conditions: Lifestyle, Healthy conditions: Activation, Patient studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: pilot group-randomized controlled trial primaryPurpose: PREVENTION masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 100 type: ESTIMATED name: Diabetes Prevention Patient Activation Clinical Decision Support Tool measure: patient activation as assessed by the Patient Activation Measure Survey (PAM) measure: number of participants referred to Diabetes Prevention Program measure: number of participants prescribed metformin measure: percent of participants who make diet changes measure: change in amount and frequency of physical activity sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06358248 id: SPHERE briefTitle: Standardized Physician-modified Fenestrated Endograft Registry acronym: SPHERE overallStatus: RECRUITING date: 2023-10-01 date: 2028-10-01 date: 2033-10-01 date: 2024-04-10 date: 2024-04-16 name: University Hospital Padova class: OTHER briefSummary: Multicenter retrospective study including all consecutive patients treated by PMEG using a standard modification technique of Valiant Captivia (Medtronic, Minneapolis, MN-USA). conditions: Aortic Aneurysm, Thoracoabdominal conditions: Aortic Diseases studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 50 type: ESTIMATED name: Physician-modification of Valiant Captivia Endograft (Medtronic, Minneapolis, MN-USA). measure: Technical success measure: Freedom from target vessel instability measure: Freedom from endograft instability measure: Early (30-days) Major Adverse Event (MAE) measure: Aneurysm sac dynamics sex: ALL minimumAge: 18 Years maximumAge: 100 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Vascular and Endovascular Clinic - Padova University status: RECRUITING city: Padova zip: 35020 country: Italy name: Michele Piazza, Pr role: CONTACT phone: 3498644688 email: michele.piazza@unipd.it lat: 45.40797 lon: 11.88586 hasResults: False
nctId: NCT06358235 id: SDU-IH-HA-01 briefTitle: The Effect of Music Therapy on Dyspnea Severity and Vital Signs overallStatus: RECRUITING date: 2024-01-07 date: 2024-05-30 date: 2024-06-30 date: 2024-04-10 date: 2024-04-10 name: Suleyman Demirel University class: OTHER briefSummary: This study aims to investigate the effect of music therapy on dyspnea severity and quality of life indicators in patients with Chronic Obstructive Pulmonary Disease (COPD) admitted to the intensive care unit. The study will be conducted at Isparta City Hospital and Kumluca State Hospital in Antalya, Turkey, using an experimental design. Patients will be divided into experimental and control groups, selected using randomization.
Patients in the experimental group will receive music therapy in the Hüseyni maqam, while those in the control group will not receive any music therapy. Life indicators and Modified Borg Scale (MBS) values of patients in the experimental group will be recorded before, immediately after, and 30 minutes post-application. Music therapy will be administered to patients for only one day, once in the morning. Data for patients in the control group will be collected at the same time intervals. The results of this study aim to contribute to the literature on the impact of music therapy on dyspnea severity and quality of life indicators in COPD patients. conditions: Dyspnea conditions: Chronic Obstructive Pulmonary Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 60 type: ESTIMATED name: Music Therapy name: No Music therapy measure: Patient Identification Form measure: Modified Borg Scale measure: Vital Signs Record Chart measure: Blood Test Results Record Chart sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Suleyman Demırel University status: RECRUITING city: Isparta zip: 32200 country: Turkey name: Hafize Aydemir role: CONTACT phone: +905078380979 email: aydemirhafize1998@gmail.com lat: 37.76444 lon: 30.55222 hasResults: False
nctId: NCT06358222 id: LUNon-invasive briefTitle: Predicting Non-small Cell Lung Cancer (NSCLC) Lymph Node Metastasis: Integrating Circulating Tumor DNA (ctDNA) Mutation/ Methylation Profiling With Positron Emission Tomography-computed Tomography (PET-CT) Scan overallStatus: RECRUITING date: 2023-12-15 date: 2027-12-31 date: 2027-12-31 date: 2024-04-10 date: 2024-04-10 name: Shanghai Chest Hospital class: OTHER briefSummary: This is a single center, prospective and observational study conducted in three stages to predict the NSCLC lymph node metastasis based on ctDNA/specific methylation molecular features combined with PET-CT imaging features and intervention study. conditions: Carcinoma conditions: Non-small Cell Lung Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 200 type: ESTIMATED name: Blood ctDNA + methylation + PET-CT and Postoperative pathology name: MRD+ methylation (or combined with PET-CT) and Invasive mediastinoscopy /EBUS-TBNA name: Intraoperative lymph node dissection measure: Negative prediction value (NPV) of lymph node metastasis rates measure: Disease-free survival (DFS) measure: ctDNA-free interval (CFI) measure: Overall Survival (OS) sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Shanghai Chest Hospital status: RECRUITING city: ShangHai country: China name: Feng Yao, PhD role: CONTACT phone: 021-22200000 email: yaofeng@shsmu.edu.cn lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06358209 id: LY2024-045-B briefTitle: Safety and Efficacy of Ventricular Irrigation for Ventriculitis overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2026-05-30 date: 2026-05-30 date: 2024-04-10 date: 2024-04-10 name: RenJi Hospital class: OTHER name: Southern Medical University, China name: First Affiliated Hospital of Zhejiang University name: 904 Hospital of the People's Liberation Army Joint Logistic Support Force name: Shenzhen Second People's Hospital name: First Affiliated Hospital of Wannan Medical College name: Huashan Hospital briefSummary: Ventriculitis is a severe infectious disease of the central nervous system with diverse etiologies. Currently, the treatment for ventriculitis is challenging, with poor prognosis. The mortality rate of ventriculitis is generally reported to be higher than 30%, with the highest reaching over 75%. Even among survivors, over 60% suffer from a variety of neurological sequelae, including cognitive impairment, gait disturbances, paralysis, behavioral disorders, and epilepsy.
Currently, treatments for ventriculitis recommended by guidelines primarily focus on the selection and administration of antibiotics, while the effects of surgical interventions have not been fully elucidated. In recent years, several studies have explored the use of ventricular irrigation in ventriculitis, indicating that ventricular irrigation techniques may accelerate the control of ventricular infection, mitigate damage to the central nervous system caused by infections, improve the prognosis of ventriculitis, and reduce complications such as hydrocephalus. However, current studies are still relatively scarce, and mostly case reports and retrospective studies. High-quality evidence is still lacking for the application of ventricular irrigation in ventriculitis.
This multicenter randomized controlled trial aims to explore the safety and effectiveness of ventricular irrigation compared to conventional treatment for severe ventriculitis, analyze the effectiveness of ventricular irrigation across different pathogen subgroups, and investigate independent risk factors for different prognostic states in patients with severe ventriculitis. conditions: Central Nervous System Infections studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 104 type: ESTIMATED name: Ventricular irrigation measure: Mortality rate measure: GOSE measure: CRS-R measure: DRS measure: mRS measure: Microbial culture measure: CSF glucose measure: CSF protein measure: CSF WBC count measure: Length of stay measure: Complications sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: First Affiliated Hospital of Wannan Medical College city: Wuhu state: Anhui country: China name: Xuefei Shao, Dr role: CONTACT lat: 31.33728 lon: 118.37351 facility: Zhujiang Hospital of Southern Medical University city: Guangzhou state: Guangdong country: China name: Qinghua Wang, Dr role: CONTACT lat: 23.11667 lon: 113.25 facility: Shenzhen Second People's Hospital city: Shenzhen state: Guangdong country: China name: Xianjian Huang, Dr role: CONTACT lat: 22.54554 lon: 114.0683 facility: 904 Hospital of the People's Liberation Army Joint Logistic Support Force city: Wuxi state: Jiangsu country: China name: Likun Yang, Dr role: CONTACT lat: 31.56887 lon: 120.28857 facility: Huashan Hospital city: Shanghai state: Shanghai country: China name: Jin Hu, Dr role: CONTACT lat: 31.22222 lon: 121.45806 facility: Renji Hospital, School of Medicine, Shanghai Jiaotong University city: Shanghai state: Shanghai country: China name: Jiyao Jiang, Dr role: CONTACT phone: 021-68383729 email: jiyaojiang@126.com name: Junfeng Feng, Dr role: CONTACT phone: 13611860825 email: fengjfmail@163.com lat: 31.22222 lon: 121.45806 facility: First Affiliated Hospital of Zhejiang University city: Hangzhou state: Zhejiang country: China name: Xiaofeng Yang, Dr role: CONTACT lat: 30.29365 lon: 120.16142 hasResults: False
nctId: NCT06358196 id: CESAH briefTitle: Complex Exploratory Study of Alcohol-Associated Hepatitis acronym: CESAH overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-04-30 date: 2026-04-30 date: 2024-04-10 date: 2024-04-10 name: Pavol Jozef Safarik University class: OTHER name: L Pasteur University Hospital name: Hospital Agel Kosice-Saca name: Technical University in Kosice name: Western University name: University of Roma La Sapienza briefSummary: Alcohol-associated hepatitis is a clinical syndrome distinct from steatohepatitis or liver cirrhosis. It is associated with high mortality and characterized by an absence of effective treatment, while corticosteroids, which are currently used as the first-line treatment are effective only in a subpopulation of patients and only on 28-days survival - their effect on survival does not last beyond this interval. The proposed study is a complex exploratory study of alcohol-associated hepatitis with several epidemiology- and prognosis-related aims. conditions: Alcoholic Hepatitis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED measure: Standardized annual incidence of (severe) alcoholic hepatitis in the Kosice Urban Area measure: Threshold of alcohol consumption associated with (an increased risk of) developing AH measure: Diagnostic accuracy of NIAAA and NIAAAm-CRP measure: Prognostic performance of Maddrey, MELD, MELD-Na, MELD 3.0, GAHS, ABIC, Lille score measure: Prognostic performance of SOFA and CLIF-C measure: An update of Maddrey, MELD, MELD-Na, MELD 3.0, GAHS, ABIC, Lille score measure: Alternative to Lille model measure: Prognostic model for 90 day survival measure: Uper limit of MELD or Maddrey scores beyond which patients no longer derive any therapeutic benefit from corticosteroid treatment measure: Natural course of nonsevere alcoholic hepatitis measure: Natural course of severe alcoholic hepatitis measure: Risk score for bacterial infection before corticosteroid treatment in patients with alcoholic hepatitis measure: Distinguishing sterile Inflammation from infection in alcoholic hepatitis measure: GUT microbiome and treatment response in alcoholic hepatitis measure: Hypothalamus-pituitary-adrenal axis and treatment response in alcoholic hepatitis measure: Adherence to outpatient psychiatric management measure: Nutritional status and treatment response in alcoholic hepatitis sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Pavol Jozef Safarik University city: Kosice zip: 04012 country: Slovakia name: Jakub Gazda, MD, PhD role: CONTACT phone: +421911115288 email: jakub.gazda@upjs.sk name: Martin Janicko, MD, PhD role: CONTACT email: martin.janicko@upjs.sk lat: 48.71395 lon: 21.25808 hasResults: False
nctId: NCT06358183 id: ESC001 briefTitle: Surgical Capacity in Zimbabwean Public Hospitals overallStatus: COMPLETED date: 2019-04-24 date: 2024-02-25 date: 2024-03-15 date: 2024-04-10 date: 2024-04-10 name: Parirenyatwa Hospital class: OTHER briefSummary: This study aimed to understand how ready Zimbabwe's public hospitals are to perform essential surgeries, which are critical for treating a wide range of health issues from emergencies like car accidents to planned procedures such as childbirth by caesarean section. The researchers looked at hospitals across Zimbabwe to see what kind of surgery facilities, equipment, and specialists were available. conditions: Surgery conditions: Anesthesia studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 80 type: ACTUAL name: No intervention measure: Bellwether procedures measure: Procedures measure: SAO density measure: Infrastructure sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Parirenyatwa Hospital city: Harare country: Zimbabwe lat: -17.82772 lon: 31.05337 hasResults: False
nctId: NCT06358157 id: CLN02001 briefTitle: The Ladera Large Bore Closure Feasibility Study overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2024-12 date: 2025-02 date: 2024-04-10 date: 2024-04-10 name: Ladera Medical class: INDUSTRY name: Avania briefSummary: This study evaluates the safety and performance of the Ladera Medical suture-mediated large bore closure (LBC) system in gaining post procedure hemostasis in subjects undergoing interventional catheterization procedures using a large-bore procedure sheath. conditions: Vascular Closure conditions: Femoral Arteriotomy Closure studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Prospective, non-randomized primaryPurpose: TREATMENT masking: NONE count: 30 type: ESTIMATED name: Ladera LBC System measure: Primary Safety Endpoint: Major Arterial Access Site Closure-related Complications measure: Primary Performance Endpoint: Time to Hemostasis measure: Secondary Safety Endpoint: Minor Arterial Access Site Closure-related Complications measure: Secondary Performance Endpoint: Time-to-Ambulation measure: Secondary Performance Endpoint: Time-to-Discharge Eligibility measure: Secondary Performance Endpoint: Incidence of Procedural Success measure: Secondary Performance Endpoint: Incidence of Device Technical Success sex: ALL minimumAge: 21 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False