hackint0sh/New-Dataset huggingface dataset:
The goal of this clinical trial is to test whether performing a knee-to-chest flexion maneuver directly after elective caesarean section will decrease the incidence of respiratory distress in term infants when compared to the standard care conditions: Transient Tachypnea of the Newborn studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: SINGLE whoMasked: PARTICIPANT count: 562 type: ESTIMATED name: Knee-to-chest-flexion manoeuvre measure: respiratory distress measure: adverse outcome of knee-to-chest flexion maneuver sex: ALL maximumAge: 30 Minutes stdAges: CHILD facility: Kilimanjaro Christian Medical Centre status: RECRUITING city: Moshi state: Kilimanjaro zip: P.O.Box 3010 country: Tanzania name: Febronia L Shirima, MD role: CONTACT phone: +255714143368 email: febbylaw17@gmail.com name: Bariki Mchome, PhD role: CONTACT phone: +255784280027 email: barikimchome@gmail.com name: Febronia L Shirima, MD role: SUB_INVESTIGATOR name: Bariki Mchome, PhD role: PRINCIPAL_INVESTIGATOR name: Blandina T Mmbaga, PhD role: PRINCIPAL_INVESTIGATOR lat: -3.35 lon: 37.33333 hasResults: False
nctId: NCT06270810 id: Aero-PA briefTitle: Cardiometabolic Effects of Combined Aerobic Exercise and Non-Exercise Physical Activity overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-11 date: 2025-03-18 date: 2025-06-01 date: 2024-02-21 date: 2024-03-15 name: Kastamonu University class: OTHER briefSummary: The goal of this clinical trial is to investigate whether increasing non-exercise physical activity combined with aerobic exercise in overweight young women is superior to performing aerobic exercise alone in terms of some cardiometabolic variables.
To answer this question, overweight young women will be randomly assigned to two different groups of this research. Volunteers in one of the groups will do moderate-intensity aerobic training and the other group will increase their non-exercise physical activities in addition to moderate-intensity aerobic training. Then researchers will compare two groups to see the differences in cardiometabolic variables. conditions: Overweight studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 32 type: ESTIMATED name: Aerobic Exercise name: Increasing non-Exercise Physical Activity measure: Low Density Lipoprotein (LDL) Cholesterol measure: High Density Lipoprotein (HDL) Cholesterol measure: Total Cholesterol measure: Glycated Hemoglobin (HbA1C) measure: Serum Triglycerides measure: Maximal Oxygen Consumption measure: Systolic Blood Pressure measure: Diastolic Blood Pressure measure: Body Fat Percentage measure: Fat-free Mass measure: Waist Circumference measure: Hip Circumference sex: FEMALE minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: Kastamonu University, Çatalzeytin Vocational School city: Çatalzeyti̇n state: Kastamonu zip: 37 country: Turkey hasResults: False
nctId: NCT06270797 id: KMUHIRB-E(I)-20230184 briefTitle: Pre-anesthesia Imaging-based Respiratory Assessment and Analysis overallStatus: RECRUITING date: 2024-03-01 date: 2026-12-31 date: 2026-12-31 date: 2024-02-21 date: 2024-02-21 name: Kaohsiung Medical University Chung-Ho Memorial Hospital class: OTHER briefSummary: This study is to establish a preoperative respiratory imaging assessment database and develop a difficult intubation risk prediction model and further risk analysis. We attempt to construct it into a pre-anesthesia intubation risk assessment software as the clinical decision support system. conditions: Clinical Decision Support System studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30000 type: ESTIMATED name: intubation for general anesthesia measure: A pre-anesthesia evaluation measure: Perform non-invasive imaging capture. measure: difficult intubation prediction measure: time to successfully extubate the nasotracheal tube after anesthesia measure: safely discharged from post-anesthesia care unit (postoperative recovery room) measure: side effects and adverse events sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Kaohsiung Medical University Chung-Ho Memorial Hospital status: RECRUITING city: Kaohsiung state: Sanmin Dist zip: 80756 country: Taiwan name: Tz Ping Gau, MD role: CONTACT phone: +886912060962 email: u9401066@gap.kmu.edu.tw lat: 22.61626 lon: 120.31333 hasResults: False
nctId: NCT06270784 id: 09.2024.122 briefTitle: Traditional vs Orthodontic Extraction of Impacted Teeth Related to the Inferior Alveolar Nerve overallStatus: RECRUITING date: 2024-01-17 date: 2024-07-17 date: 2024-09-17 date: 2024-02-21 date: 2024-02-21 name: Marmara University class: OTHER briefSummary: The aim of this clinical study was to compare the effects of traditional and orthodontic extraction methods on postoperative nerve damage in impacted third molars associated with the inferior alveolar nerve. The main question it aims to answer is:
Researchers will compare traditional and orthodontic extraction methods to see if extraction methods affect postoperative nerve damage. conditions: Inferior Alveolar Nerve Injuries studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 30 type: ESTIMATED name: Traditional Extraction name: Orthodontic Extraction measure: The effect of the extraction method on nerve injury measure: 2-point discrimination test sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Marmara University status: RECRUITING city: Istanbul state: Basibuyuk zip: 34854 country: Turkey name: Senem Askin Ekinci, DDS role: CONTACT phone: +902167775000 email: askinsenem@gmail.com lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06270771 id: 5823 briefTitle: OURA Ring Wearable Testing in MDS Patients: a Feasibility and Discovery Pilot Study acronym: OURA MDS overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2025-08-01 date: 2026-02-01 date: 2024-02-21 date: 2024-02-21 name: Sunnybrook Health Sciences Centre class: OTHER briefSummary: A prospective, single center, single arm phase 2 cohort feasibility study of the OURA ring in adult MDS patients. Patients with MDS will wear the OURA ring and upload biometrics weekly. Quality of life measures will be clinically evaluated and correlated with biometrics. We hypothesize that it will be feasible for MDS patients to wear the OURA ring 70% of the time for 3 months. conditions: MDS conditions: Myelodysplastic Syndromes studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 60 type: ESTIMATED name: OURA Ring measure: Feasibility of patients with MDS wearing the OURA ring measure: Exploratory correlations between physiologic changes captured by the wearable device and physical functioning sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sunnybrook Health Sciences Research Centre city: Toronto state: Ontario zip: M4N 3M5 country: Canada name: Rena Buckstein role: CONTACT phone: 416-480-5000 phoneExt: 689565 email: rena.buckstein@sunnybrook.ca name: Geetha Yogendran role: CONTACT phone: 416-480-5000 phoneExt: 689565 email: geetha.yogendran@sunnybrook.ca name: Rena Buckstein role: PRINCIPAL_INVESTIGATOR lat: 43.70011 lon: -79.4163 hasResults: False
nctId: NCT06270758 id: 453/2023/Sper/IOR briefTitle: Clinical Validation of BBCT-hip acronym: ValidaBBCT-hip overallStatus: RECRUITING date: 2023-11-07 date: 2030-11-06 date: 2030-11-06 date: 2024-02-21 date: 2024-02-21 name: Istituto Ortopedico Rizzoli class: OTHER briefSummary: The clinical study is aimed at assessing the accuracy of the in silico methodology BBCT-hip. BBCT-hip takes as inputs the subject-specific height and weight, and the CT scan of his femur to predict the risk of fracture for the femur upon falling. In the study, 150 subjects who suffered from a fracture will be enrolled, in addition to 150 control subjects. CT scans will be carried out for both groups (no later than 3 months for the fracture group) and BBCT-hip run,in order that the risk of fracture will be obtained. First, a transversal study will be performed, where the stratification accuracy of BBCT-hip will be assessed in terms of the ability of the predicted risk of fracture to separate fracture and control subjects. Furthermore, the control subjets will be followed up to assess BBCT-hip predictive accuracy through a longitudinal study. conditions: Osteoporosis studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 300 type: ESTIMATED name: CT scan at the femur measure: Femoral fracture event measure: BBCT-hip risk prediction measure: T-score sex: FEMALE minimumAge: 65 Years maximumAge: 85 Years stdAges: OLDER_ADULT facility: Rizzoli Orthopaedic Institute status: RECRUITING city: Bologna zip: 40136 country: Italy name: Alessandra Aldieri, PhD role: CONTACT phone: +390516366565 email: alessandra.aldieri@ior.it name: Fabio Baruffaldi role: CONTACT phone: +390516366850 email: fabio.baruffaldi@ior.it lat: 44.49381 lon: 11.33875 facility: Rizzoli Orthopaedic Institute status: RECRUITING city: Bologna zip: 40136 country: Italy name: Alessandra Aldieri, PhD role: CONTACT phone: +39 051 636 6565 email: alessandra.aldieri@polito.ior.ir name: Fabio Baruffaldi role: CONTACT phone: + 39 051 6366850 email: fabio.baruffaldi@ior.it lat: 44.49381 lon: 11.33875 hasResults: False
nctId: NCT06270745 id: sdycllyy001 briefTitle: ICG Anastomotic Control in Digestive System Surgery overallStatus: RECRUITING date: 2018-01-01 date: 2024-02-01 date: 2024-06-01 date: 2024-02-21 date: 2024-02-23 name: Shandong Linglong Yingcheng Hospital class: NETWORK briefSummary: This was a parallel single-center retrospective cohort study conducted at Linglong Yingcheng Hospital, Shandong, China. The purpose of this study was to investigate the effect of indocyanine green (ICG) on patients undergoing digestive system surgery (subtotal gastrectomy, partial hepatectomy, transverse colectomy, left colectomy, including sigmoid resection, and splenic colic resection). ) of anastomotic leakage (AL). Secondary objectives were to detect and study the impact of various risk factors on AL and on morbidity and surgical performance within 30 days of surgery. conditions: Surgical Anastomosis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 200 type: ESTIMATED name: indocyanine green measure: Anastomotic leak at 30 days measure: Post-operative morbidity sex: ALL minimumAge: 18 Years maximumAge: 90 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Shandong Linglong Yingcheng Hospital status: RECRUITING city: Yantai state: Shandong zip: 264000 country: China name: Xuan Qiu, MD role: CONTACT phone: 8618354280081 email: qiuxuan100@163.com name: Ni Wang, MD role: CONTACT phone: 8618705353551 email: wangni1989@163.com lat: 37.47649 lon: 121.44081 hasResults: False
nctId: NCT06270732 id: PID2021-125444OB-100-II-iM briefTitle: Efficacy of iMentalize and MISC-SA to Foster Parents' Mentalization and Children Mental Health in General Population. acronym: iMentalize overallStatus: RECRUITING date: 2024-02-05 date: 2025-02-21 date: 2025-03-03 date: 2024-02-21 date: 2024-02-21 name: Universitat Autonoma de Barcelona class: OTHER name: Ministerio de Economía y Competitividad, Spain briefSummary: OBJECTIVES: The goal of this parallel randomized controlled trial is to test the efﬁcacy of the iMentalize program and the Mediational Intervention for Sensitizing Caregivers - Self Administered version (MISC-SA) to foster parents' mentalization and children mental health in families from general population.
PARTICIPANTS will randomly receive one of the 3 interventions, all based in 30 weekly online non-synchronic sessions extended across 1 year: the iMentalize program (based on parent-child sessions where they see and talk about cartoon shorts), the MISC-SA (self-administered MISC version based on guided video-feedback using recordings of one's own parent-child interactions), and MISC-R (also self-administered but mainly based on readings and cognitive exercises instead of video-feedback), which is used here as Treatment as Usual (TAU, control group) because it is the most similar to most other intellectual and mainly theoretical trainings.
* MISC-SA shows efficacy in fostering parent's mentalization and children mental health compared with TAU (control group). conditions: Emotional Intelligence conditions: Social Interaction conditions: Mental Health Wellness 1 conditions: Well-Being, Psychological studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Double-blind, parallel group, randomized controlled trial primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 105 type: ESTIMATED name: iMentalize Program (iMentalize) name: Mediational Intervention for Sensitizing Caregivers, Self-Administered version (MISC-SA) name: Mediational Intervention for Sensitizing Caregivers - Readings version (MISC-R): Treatment as Usual (TAU) measure: Parental Reﬂective Function Questionnaire (PRFQ) measure: Trait Meta-Mood Scale (24 items) (TMMS-24) measure: Basic Empathy Scale (BES) measure: Movie for the Assessment of Social Cognition (MASC) measure: Stirling Children's Wellbeing Scale (SCWBS) measure: Child Well-Being Level (CWBL) measure: Strengths and Difﬁculties Questionnaire (SDQ) measure: Achenbach System for Empirically Assessment (ASEBA) measure: Observing Mediational Interaction (OMI) measure: Parental Stress Questionnaire (PSI) measure: Goldberg Health Questionnaire (28 items) (GHQ-28) measure: Difﬁculties in Emotional Regulation Scale (DERS) measure: Oxford Happiness Questionnaire (OHQ) measure: Rosenberg's Self-Esteem Scale (RSES) measure: Parental Sense of Competence Scale (PSOC) measure: Self-Other Mentalization Scale (SOMS) measure: Reﬂective Functioning Scale - Youth (5 items version) (RFQ-Y5) measure: Trait Meta-Mood Scale - Children version (TMMS-C) measure: Big Five Questionnaire for Children and Adolescents (BFQ-NA) measure: BarOn Inventory of Emotional Intelligence for children aged 7 to 18 years old (BarOn) measure: Rosenberg's Self-Esteem Scale - Child version (RSES-C) measure: Battery of Socialization (BAS) measure: Inventory of Learning Patterns, reduced version (60 items) (ILP-60) measure: Relationship Questionnaire (RQ) measure: Time with the Child (TC) sex: ALL minimumAge: 25 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sergi Ballespí status: RECRUITING city: Barcelona zip: 08193 country: Spain name: Anna Ciraso, Researcher role: CONTACT phone: +34661858272 email: anna.ciraso@uab.cat name: Ana Carolina Pacheco, Researcher role: CONTACT phone: +573153561564 email: anacarolina.pacheco@autonoma.cat lat: 41.38879 lon: 2.15899 facility: Universitat Autònoma de Barcelona status: RECRUITING city: Barcelona zip: 08193 country: Spain name: Anna Ciraso, Researcher role: CONTACT phone: +34661858272 email: anna.ciraso@uab.cat name: Ana Carolina Pacheco, Researcher role: CONTACT phone: +573153561564 email: anacarolina.pacheco@autonoma.cat lat: 41.38879 lon: 2.15899 hasResults: False
nctId: NCT06270706 id: PLN-101095-ONC-101 briefTitle: A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors overallStatus: RECRUITING date: 2023-08-30 date: 2025-06 date: 2025-12 date: 2024-02-21 date: 2024-02-21 name: Pliant Therapeutics, Inc. class: INDUSTRY briefSummary: This is a Phase 1a/1b, dose-escalation/expansion, consecutive-cohort, open-label study to evaluate the safety, tolerability, PK, PD, and preliminary evidence of antitumor activity of PLN-101095 in combination with pembrolizumab (the study treatment regimen) in adult participants with advanced or metastatic solid tumors for which pembrolizumab is indicated but have documented disease progression (refractory \[primary resistance\]) or relapsed \[secondary resistance\]) after at least 3 months from the start of treatment with pembrolizumab.
* Part 2: Dose-expansion cohorts using Simon's 2-stage design conditions: Metastatic Solid Tumor studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: NONE count: 77 type: ESTIMATED name: PLN-101095 name: Pembrolizumab measure: Proportion of participants with treatment-emergent adverse events and serious adverse events per CTCAE Version 5.0. measure: Number of participants with a Dose Limiting Toxicity (DLT) defined as toxicities that meet predefined severity criteria, assess as having a suspected relationship to study drug, unrelated to disease, inter-current illness, or concomitant medications. measure: Maximum observed plasma concentration (Cmax) to characterize the plasma pharmacokinetics (PK). measure: Time to maximum observed concentration (Tmax) to characterize the plasma pharmacokinetics (PK). measure: Area under the concentration-time curve over a dosing interval (AUC0-τ) to characterize the plasma pharmacokinetics (PK). measure: Disease control rate (DCR) is defined by the proportion of participants who maintain disease control (iCR, iPR or iSD) per iRECIST Version 1.1. measure: Objective response rate (ORR) is defined by the proportion of participants with an iCR or iPR per iRECIST Version 1.1. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: South Texas Accelerated Research Therapeutics (START) status: RECRUITING city: Grand Rapids state: Michigan zip: 49546 country: United States lat: 42.96336 lon: -85.66809 facility: NEXT Austin status: RECRUITING city: Austin state: Texas zip: 78758 country: United States lat: 30.26715 lon: -97.74306 facility: University of Texas MD Anderson Cancer Center status: RECRUITING city: Houston state: Texas zip: 77030 country: United States lat: 29.76328 lon: -95.36327 facility: NEXT Virginia status: RECRUITING city: Fairfax state: Virginia zip: 22031 country: United States lat: 38.84622 lon: -77.30637 hasResults: False
nctId: NCT06270693 id: Dr Sushma briefTitle: hsCRP & CH Indices in Patients With Coronary Artery Disease With and Without Apical Periodontitis overallStatus: ACTIVE_NOT_RECRUITING date: 2022-11-01 date: 2024-02-01 date: 2024-04-01 date: 2024-02-21 date: 2024-02-21 name: Postgraduate Institute of Dental Sciences Rohtak class: OTHER briefSummary: Endodontic treatment is done in Patients with chronic pulp exposure in patients with Coronary Artery Disease and systemic inflammatory markers recorded before and and after treatment and compared with patients with Coronary Artery Disease without chronic pulp exposure. conditions: Apical Periodontitis conditions: Coronary Artery Disease studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 70 type: ACTUAL name: Endodontic treatment measure: Serum hsCRP measure: complete hemogram indices measure: Periapical index SCORE CHANGE sex: ALL minimumAge: 40 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: PGIDS city: Rohtak state: Haryana zip: 124001 country: India lat: 28.89447 lon: 76.58917 hasResults: False
nctId: NCT06270680 id: STUDY00023019 briefTitle: Carotenoids for Collision Athletes overallStatus: NOT_YET_RECRUITING date: 2024-08-01 date: 2024-12-20 date: 2024-12-20 date: 2024-02-21 date: 2024-03-18 name: Penn State University class: OTHER name: MacuHealth name: Orlando Regional Medical Center briefSummary: This is a supplement study being conducted to find out if collision sport athletes who are exposed to repetitive head impacts while supplementing with carotenoids will have decreased pro-inflammatory blood biomarkers, increases in macular pigment optical density, improved contrast sensitivity, greater retinal nerve fiber thickness, and better overall visual quality of life scores compared to collision athletes taking a placebo. conditions: Head Injury conditions: Carotenoids studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 52 type: ESTIMATED name: Vision Edge Pro name: Placebo measure: Blood and saliva biomarkers via venous blood draw and spitting into sterile cup. measure: Visual Performance: Speed of visual processing measure: Visual Performance: Contrast Sensitivity measure: Skin carotenoid concentration measure: Retinal Nerve Fiber Layer Thickness measure: Macular Pigment Optical Density measure: Visual Quality of Life Scores measure: Visual Quality of Life Scores measure: Demographic information measure: Demographic information sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Pennsylvania State University city: University Park state: Pennsylvania zip: 16802 country: United States name: Semyon Slobounov, PhD role: CONTACT phone: 814-571-4298 email: sms18@psu.edu name: Jonathan Kelly, MS role: CONTACT phone: 9495565035 email: jtk5577@psu.edu name: Semyon Slobounov, PhD role: PRINCIPAL_INVESTIGATOR lat: 40.80201 lon: -77.85639 hasResults: False
nctId: NCT06270667 id: LYMfit briefTitle: Effects of Exercise Training in Survivors of Lymphoma acronym: LYMfit overallStatus: RECRUITING date: 2024-03-20 date: 2028-09-01 date: 2028-09-01 date: 2024-02-21 date: 2024-03-22 name: Norwegian School of Sport Sciences class: OTHER name: Uppsala University briefSummary: This study aims to compare the effects of aerobic exercise with or without addition of resistance exercise to usual care in individuals treated with anthracyclines for lymphomas and to compare exercise effects to age- and sex-matched individuals with no prior history of malignant diseases. conditions: Lymphoma conditions: Physical Exercise conditions: Cardiotoxicity conditions: Cardiovascular Diseases conditions: Chemotherapeutic Toxicity studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 280 type: ESTIMATED name: Aerobic Exercise name: Combined Aerobic and Resistance Exercise measure: VO2peak measure: Systolic- and diastolic heart chamber dimensions measure: Systolic- and diastolic longitudinal strain measure: Lean body mass measure: Fat mass measure: Forced Vital Capacity measure: Forced Expiratory Volume 1 sec measure: Maximal voluntary ventilation measure: Diffusion capacity measure: Physical activity measure: Physical activity measure: Global Health related Quality of life measure: Blood volume measure: Muscle fiber area measure: Muscle fiber type measure: Muscle mitochondria mass measure: Muscle genome-wide DNA methylation and gene expression measure: Adverse events sex: ALL minimumAge: 20 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Norweigan School of Sport Sciences status: NOT_YET_RECRUITING city: Oslo country: Norway name: Tormod S. Nilsen, PhD role: CONTACT lat: 59.91273 lon: 10.74609 facility: Helena Igelström status: RECRUITING city: Uppsala country: Sweden name: Helena Igelström, PhD role: CONTACT name: Anna Henriksson, PhD role: CONTACT phone: 709394175 phoneExt: 0046 email: anna.km.henriksson@uu.se name: Helena Igelström, PhD role: PRINCIPAL_INVESTIGATOR name: Anna Henriksson, PhD role: SUB_INVESTIGATOR lat: 59.85882 lon: 17.63889 hasResults: False