hackint0sh/New-Dataset huggingface dataset:
Researchers will compare the Praxis and Control group to determine if the Praxis group shows improvement over the control group with respect to the military-relevant behavioral performance outcomes and patient-reported symptom scores after the end of the rehabilitation. conditions: Brain Concussion conditions: Vestibular Disorder conditions: Cognition Disorder conditions: Mild Traumatic Brain Injury studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: DEVICE_FEASIBILITY masking: NONE count: 30 type: ESTIMATED name: Praxis name: Supervised cardiovascular exercise measure: Perceived usability of the Praxis system measured by the System Usability Scale (SUS) measure: Change in Dizziness Handicap Inventory (DHI) score measure: Change in Pittsburgh Sleep Quality Index (PSQI) score measure: Change in Generalized Anxiety Disorder scale (GAD-7) score measure: Change in Post-Traumatic Stress Disorder Check List - Military Version (PCL-M) score measure: Change in Vestibular Activities Avoidance Instrument-9 (VAAI-9) score measure: Change in Headache Impact Test-6 (HIT-6) score measure: Change in Santa Barbara Sense of Direction Scale (SBSOD) score measure: Change in time required to perform 300-yard shuttle run (single- and dual-task) measure: Change in perceived fogginess measure: Change in time required to perform 5-10-5 shuttle run measure: Change in score for 4-Item Hybrid Assessment of Mobility for mTBI (HAM-4-mTBI) measure: Change in time required to perform POrtable WARrior Test Of Tactical AgiLity (POWAR-TOTAL) (single- and dual-task) measure: Change in Vestibular/Ocular Motor Screening (VOMS) total symptom score measure: Compliance with 20-minute daily dose of gaze stability exercises sex: ALL minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Brooke Army Medical Center city: Fort Sam Houston state: Texas zip: 78234 country: United States lat: 29.45746 lon: -98.4472 hasResults: False
nctId: NCT06314451 id: HAS.22.11.035 briefTitle: Cross-condition Validation of the Steroid PRO overallStatus: RECRUITING date: 2022-06-01 date: 2024-05-31 date: 2024-05-31 date: 2024-03-18 date: 2024-03-20 name: University of the West of England class: OTHER name: Johns Hopkins University name: University of Pittsburgh briefSummary: Testing a questionnaire about treatment with steroids for skin, lung or gastric conditions conditions: Inflammatory Disease conditions: Immune System Disorder conditions: Gastrointestinal Diseases conditions: Dermatologic Disease conditions: Respiratory Disease studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 60 type: ESTIMATED name: Cognitive Interview measure: Steroid PRO sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of the West of England status: RECRUITING city: Bristol zip: BS2 8HW country: United Kingdom name: Joanna C Robson role: CONTACT phone: 01173427417 email: Jo.Robson@uwe.ac.uk lat: 51.45523 lon: -2.59665 hasResults: False
nctId: NCT06314438 id: STUDY00017189 id: UL1TR002319 type: NIH link: https://reporter.nih.gov/quickSearch/UL1TR002319 briefTitle: Culturally-Responsive Curriculum for Caregivers With Children at Autism Likelihood overallStatus: ACTIVE_NOT_RECRUITING date: 2023-12-15 date: 2024-03-15 date: 2024-03-15 date: 2024-03-18 date: 2024-03-18 name: University of Washington class: OTHER name: National Center for Advancing Translational Sciences (NCATS) briefSummary: The goal of this clinical trial is to examine how helpful and relevant the Family Care Project workbook is for families from culturally and linguistically diverse backgrounds who have a young child at autism likelihood. The main questions this trial aims to answer are:
Participants will complete surveys that elicit their feedback on their use of the workbook. conditions: Autism conditions: Development Delay studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 41 type: ACTUAL name: Family Care Project measure: Staff Training Feedback Survey of Implementation Properties (self-report) measure: Staff Competence in Assisting Families with Children at-autism Likelihood Survey (self-report) measure: The Maternal Self-Efficacy Scale Questionnaire measure: Caregiver Knowledge and Use of Behaviors that Support Children at autism-likelihood Survey measure: Current Services Utilized by Families to Support Children at autism-likelihood Survey measure: Family Care Project Feedback Survey of Implementation Properties sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mother Africa city: Kent state: Washington zip: 98032 country: United States lat: 47.38093 lon: -122.23484 hasResults: False
nctId: NCT06314425 id: IRB_20240714 briefTitle: Zirconia Implants: Practice-based Evidence acronym: SDS overallStatus: RECRUITING date: 2024-04-28 date: 2024-05 date: 2025-12 date: 2024-03-18 date: 2024-04-16 name: Swiss Dental Solutions class: INDUSTRY name: VISTA Institute for Therapeutic Innovations briefSummary: This study is a prospective case series clinical study to examine the effectiveness of Ceramic dental implants manufactured by Swiss Dental Solutions (SDS). Participants with an indication from the dentist for teeth extraction and replacement are invited to participate in this study. Participating in this study will involve the use of dental implants manufactured by Swiss Dental Solutions (SDS zirconia dental implants), submission of the case data, including pre-operative information, intra-operative details, and post-operative follow-up data, to the study site and its collaborating partners.
The SDS zirconia dental implants used in this research are FDA cleared devices that are available for dental treatments. conditions: Dental Implants conditions: Ceramic Implant studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 100 type: ESTIMATED name: Immediate dental implants placements on fresh sockets after tooth extraction measure: Cumulative Survival Rate (CSR) measure: Marginal Bone Loss (MBL) measure: Pink Esthetic Score (PES) sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Brighton Periodontal & Implant Dental Group status: RECRUITING city: Woodland Hills state: California zip: 91367 country: United States name: Homayoun Zadeh, PhD, DDS role: CONTACT phone: 818-703-7733 email: homazadeh@gmail.com name: Etyene Schnurr, PhD, DDM role: CONTACT phone: 0797213110 email: etyene.schnurr@swiss-biohealth.com lat: 34.16834 lon: -118.60592 hasResults: False
nctId: NCT06314412 id: 24C211 briefTitle: Transcutaneous Posterior Tibial Nerve Stimulation in Patients With Multiple Sclerosis Related Urge Incontinence acronym: SANS-REHAB overallStatus: RECRUITING date: 2023-02-13 date: 2025-04 date: 2025-07 date: 2024-03-18 date: 2024-03-18 name: Istituto Auxologico Italiano class: OTHER briefSummary: Recently, several studies have investigated the safety and efficacy of the Stoller afferent nerve stimulation (SANS) treatment in Multiple Sclerosis (MS) patients. However, because of the differences among the published protocols (percutaneous versus transcutaneous stimulation, stimulation site, total number of sessions), and the absence of data on the duration of the effect, this treatment is not yet currently included in the rehabilitation programs. The present study aims at evaluating the efficacy of a protocol of SANS in the short- and medium-term follow-up.
The efficacy of the proposed stimulation protocol on the physiological parameters of bladder function will be also investigated. conditions: Multiple Sclerosis studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 20 type: ESTIMATED name: Stoller's Afferent Nerve Stimulation (SANS) measure: Measure of variation of incontinence. measure: Measure of variation of urinary urgency sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Istituto Auxologico Italiano status: RECRUITING city: Milan zip: 20122 country: Italy name: Laura Perucca, MD role: CONTACT phone: +3902619116247 email: l.perucca@auxologico.it name: Nicole Bompani, MD role: CONTACT phone: +3902619116151 email: n.bompani@auxologico.it lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06314399 id: 2023-18 id: DVO005 2555-CV1837 type: OTHER domain: Universidad del Rosario Research Ethics Committee briefTitle: Predictive Factors Associated to Bile Cultures and Antibiogram Resistance in Patients With Laparoscopic Cholecystectomy acronym: BACILO overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-12 date: 2026-06 date: 2024-03-18 date: 2024-03-18 name: Hospital Universitario Mayor Méderi class: OTHER name: Universidad del Rosario briefSummary: The BACILO study was designed with the objective of having robust data on local epidemiological bacterial colonisation information on bile cultures with patients taken to laparoscopic cholecystectomy in our institution to find which predictive factors are associated with culture positivity and antibiotic resistance patterns. Secondary endpoints include evaluating demographical, clinical and surgical variables and establishing comparison between both positive and negative bile cultures and between antibiotic sensitive and resistant microorganism strain isolations. conditions: Biliary Infection conditions: Antibiotic Resistant Strain studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 703 type: ESTIMATED name: Bile culture and phenotypic antibiogram resistance test measure: Bile culture positivity measure: Phenotypical antibiogram resistance measure: Microbial characteristics measure: Bile culture and antibiotic resistance relationship measure: Demographical and clinical characteristics measure: Surgical characteristics and outcomes measure: Determination of predictive factors (age, diabetes mellitus, choledocholithiasis / ERCP, C-reactive protein, cholecystitis and Tokyo guidelines severity of cholecystitis) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06314386 id: 23.139.01 id: R01NR020866 type: NIH link: https://reporter.nih.gov/quickSearch/R01NR020866 briefTitle: Systems Analysis and Improvement Approach to Prevent TB acronym: SAIA-TB overallStatus: NOT_YET_RECRUITING date: 2025-01-06 date: 2028-02-29 date: 2029-02-28 date: 2024-03-18 date: 2024-03-18 name: Boston College class: OTHER name: National Institutes of Health (NIH) name: Boston University name: University of Washington name: Medical Research Council, South Africa name: National Institute of Nursing Research (NINR) briefSummary: This randomized trial uses the evidence-based Systems Analysis and Improvement Approach (SAIA) adapted for tuberculosis (SAIA-TB) to assess the comprehensive tuberculosis (TB) care cascade across 16 clinics in rural Eastern Cape, South Africa to improve patient outcomes. The aims of this study are to:
The investigators hypothesize that SAIA-TB implementation will lead to a 20% increase in each of: TB screening, TB preventive treatment initiation, and TB disease treatment initiation during the 18-month intervention period. conditions: Tuberculosis conditions: TPT conditions: TB - Tuberculosis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Stepped Wedge Crossover Cluster primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 19560 type: ESTIMATED name: Systems Analysis and Improvement Approach for TB (SAIA-TB) measure: TB Screening measure: Linkage to care for TB disease treatment measure: TB Evaluation measure: TB Diagnosis measure: Successful TB Prevention Treatment (TPT) Outcome measure: Successful TB Outcome sex: ALL minimumAge: 0 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Addo Clinic city: Addo country: South Africa lat: -33.54833 lon: 25.6899 facility: Lukhanyiso Clinic city: Addo country: South Africa lat: -33.54833 lon: 25.6899 facility: Kwa-Nonqubela Clinic city: Alexandria country: South Africa facility: Marselle Clinic city: Boesmansriviermond country: South Africa lat: -33.6863 lon: 26.65604 facility: Masakhane Clinic city: Hankey country: South Africa lat: -33.83308 lon: 24.88359 facility: Humansdorp Clinic city: Humansdorp country: South Africa lat: -34.02903 lon: 24.76912 facility: Pellsrus Clinic city: Jeffrey's Bay country: South Africa lat: -34.05031 lon: 24.90762 facility: Joubertina CHC city: Joubertina country: South Africa lat: -33.82547 lon: 23.85618 facility: Louterwater Clinic city: Joubertina country: South Africa lat: -33.82547 lon: 23.85618 facility: Twee Riviere Clinic city: Joubertina country: South Africa lat: -33.82547 lon: 23.85618 facility: Kareedouw Clinic city: Kareedouw country: South Africa lat: -33.9528 lon: 24.29053 facility: Kenton On Sea Clinic city: Kenton on Sea country: South Africa lat: -33.68421 lon: 26.67036 facility: Kirkwood Clinic city: Kirkwood country: South Africa lat: -33.39829 lon: 25.44279 facility: Moses Mabida Clinic city: Kirkwood country: South Africa lat: -33.39829 lon: 25.44279 facility: Imizamo Yetho Clinic city: Patensie country: South Africa lat: -33.76007 lon: 24.81383 facility: Nkwenkwezi Clinic city: Port Alfred country: South Africa lat: -33.58601 lon: 26.88329 hasResults: False
nctId: NCT06314373 id: HSK39775-101/201 briefTitle: A Study for HSK39775 in Participants With Solid Tumors overallStatus: RECRUITING date: 2024-03-07 date: 2028-02-01 date: 2028-09-01 date: 2024-03-18 date: 2024-03-18 name: Xizang Haisco Pharmaceutical Co., Ltd class: INDUSTRY briefSummary: This research is designed to determine if HSK39775 is safe, tolerable, and has anti-cancer activity in patients with advanced solid tumors. conditions: Advanced Solid Tumors studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 243 type: ESTIMATED name: HSK39775 Monotherapy measure: AE/SAE measure: DLT measure: MTD/MAD measure: Maximum Plasma Concentration [Cmax] measure: Area Under Curve[AUC] measure: Time to maximum observed concentration [Tmax] measure: Elimination half-life [t1/2] measure: Overall Response Rate (ORR) per RECIST V1.1 measure: Progression Free Survival measure: Time To Response measure: Disease Control Rate measure: Best percentage change in target lesion sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fundan University Shanghai Cancer Center status: RECRUITING city: Shanghai state: Shanghai zip: 200032 country: China lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06314360 id: BAP_PFS briefTitle: Comparison of Foot Posture, Plantar Pressure, and Postural Balance in Patellofemoral Pain Patients and Healthy Subjects overallStatus: ENROLLING_BY_INVITATION date: 2024-03 date: 2024-06 date: 2024-10 date: 2024-03-18 date: 2024-03-18 name: Hacettepe University class: OTHER briefSummary: Patellofemoral pain syndrome (PFS) is a musculoskeletal problem characterized by pain felt in the front of the knee or behind the patella, commonly affecting individuals in adolescence or young adulthood, especially those engaged in sports such as cycling and running. It is one of the most encountered knee injuries and can have a poor prognosis. The intensity of knee pain increases during functional activities such as stair climbing, squatting, running, and jumping due to the increased patellofemoral joint reaction force.
A disturbance in postural stability is observed in individuals with PFS due to pain during functional activities. Studies examining changes in foot posture, plantar pressure, and postural balance in individuals with PFS are quite limited and controversial. Moreover, research that simultaneously investigates these parameters and interprets the results is scarce. Some studies have utilized detailed technical systems such as medical imaging or motion analysis, while practical methods incorporating foot posture and plantar pressure analyses are available and easy to use in clinical settings.
The use of practical and fast assessment methods in planning treatments for PFS is crucial for early rehabilitation planning. Practical methods such as foot posture, plantar pressure, and postural balance assessments, which can be used in clinical settings, may provide benefits in shaping rehabilitation goals related to lower extremity alignment in individuals with PFS. The objective of this study is to compare the foot posture, plantar pressure, and postural stability of individuals with PFS with healthy individuals. Additionally, the investigators aim to investigate the relationship between foot posture, plantar pressure parameters, postural balance, and functional level in individuals with PFS. Through these objectives, it will be possible to identify potential parameters that could be effective in rehabilitation processes and contribute to determining treatment programs by revealing biomechanical changes in individuals with PFS. conditions: Patellofemoral Pain Syndrome studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 50 type: ESTIMATED name: No intervention. measure: Plantar Pressure measure: Postural Stability measure: Foot posture measure: Functionality measure: Pain Assessment measure: Limb dominance sex: ALL minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Hacettepe University city: Ankara state: Ankara/Sıhhıye zip: 06100 country: Turkey lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06314347 id: gibtuipekkirmaci briefTitle: Reference Value of Figure of 8 Walk Test overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-10-30 date: 2024-11-30 date: 2024-03-18 date: 2024-03-18 name: Gaziantep Islam Science and Technology University class: OTHER briefSummary: The aim of the study is to determine the reference values of the Figure 8 Walking Test in healthy adults. conditions: Healthy studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 1000 type: ESTIMATED name: Figure of 8 walk test measure: Figure of 8 walk test measure: Age measure: gender measure: height measure: weight sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06314334 id: SHCA-NKT-202301 briefTitle: Screening Study of Combined Sequential Chemotherapy and Radiation Therapy for Early-stage NK/T-cell Lymphoma overallStatus: RECRUITING date: 2023-03-04 date: 2026-12-30 date: 2028-12-30 date: 2024-03-18 date: 2024-03-18 name: Fudan University class: OTHER briefSummary: Extranodal NK/T-cell lymphoma, nasal type (NKTCL) is a common malignant tumor in East Asian populations, often starting in the nasal cavity and spreading to other organs. Associated with EBV infection, NKTCL is aggressive. Early-stage patients typically receive chemo and radiotherapy, with promising outcomes. Recent studies show the potential of immune checkpoint inhibitors in NKTCL treatment. However, optimal treatment sequencing and efficacy remain unclear. This study aims to compare three strategies: (A) Pegaspargase with Sintilimab and radiotherapy; (B) chemo then radiotherapy (PGemOx); (C) sandwich chemoradiotherapy (GELAD). The goal is to identify the best treatment based on 24-month progression-free survival. conditions: Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Participants were stratified according to the NRI prognostic index obtained from the baseline assessment (NRI \<2, NRI ≥2) and randomly assigned to three groups receiving different experimental treatments.
Group C (sandwiched radiotherapy group) received 2 cycles of the GELAD regimen chemotherapy initially, followed by radiotherapy and another two cycles GELAD chemotherapy. primaryPurpose: TREATMENT masking: NONE count: 210 type: ESTIMATED name: Sintilimab+Pegaspargase name: P-GemOx name: GELAD name: IMRT measure: PFS24 measure: ORR measure: OS measure: EFS measure: TRAE sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fudan University Shanghai Cancer Center status: RECRUITING city: Shanghai state: Shanghai zip: 200032 country: China name: Rong Tao, MD role: CONTACT phone: 8621-64175590 email: rtao@shca.org.cn name: Chuanxu Liu, MD role: CONTACT phone: 8621-64175590 email: liuchuanxu@shca.org.cn name: Rong Tao, MD role: PRINCIPAL_INVESTIGATOR lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06314321 id: 2021-K151-01 briefTitle: The Effect of Baduanjin on Shoulder Function in Maintenance Hemodialysis Patients overallStatus: COMPLETED date: 2022-01-01 date: 2023-06-30 date: 2024-02-20 date: 2024-03-18 date: 2024-03-29 name: Affiliated Hospital of Nantong University class: OTHER briefSummary: The aim of this study is to examine the effect of 18-month Baduanjin exercise on shoulder joint function in maintenance hemodialysis (MHD) patients. 60 MHD patients aged 18-75 will included in this study and randomly divided into two groups (intervention group and control group). The intervention group will be led by a professional person and underwent Baduanjin exercise three times a week before hemodialysis. The control group maintained routine treatment and daily activities. conditions: Hemodialysis Complication conditions: Shoulder Joint Disorder conditions: CKD-MBD studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 60 type: ACTUAL name: Baduanjin exercise measure: Shoulder joint function score measure: Shoulder joint internal rotation function measure: Muscle strength measurement measure: Area of biceps brachii muscle measure: Changes in the Short Form-36 (SF-36) and European Quality of Life Five Dimension（EQ-5D-5L） measure: Changes in the Hospital Anxiety and Depression Scale （HADS） sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Affiliated Hospital of Nantong University city: Nantong state: Jiangsu zip: 226000 country: China lat: 32.03028 lon: 120.87472 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2021-11-30 uploadDate: 2024-03-12T09:17 filename: Prot_SAP_000.pdf size: 148387 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2021-11-30 uploadDate: 2024-03-12T09:19 filename: ICF_001.pdf size: 165056 hasResults: False
nctId: NCT06314308 id: AAAU8161 id: 5P30AG064198-05 type: NIH link: https://reporter.nih.gov/quickSearch/5P30AG064198-05 briefTitle: Community Health Worker Assisted Task Specific and Cognitive Therapy at Home With Exposure After Stroke acronym: CATCHES overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-05 date: 2025-05 date: 2024-03-18 date: 2024-03-26 name: Columbia University class: OTHER name: National Institute on Aging (NIA) briefSummary: CATCHES is a novel intervention for preliminary testing, integrating Task Specific Therapy at home guided by Community Health Workers (CHW) under supervision of a licensed Physical Therapist (PT) guided by telehealth based Cognitive Behavioral Therapy (CBT) to reduce task specific fears through repetitive exposure and adaptive behavioral activation strategies and facilitate engagement in physical activity.