hackint0sh/New-Dataset huggingface dataset:
The research is planned to start on 01.01.2024. Participants will be divided into experimental and control groups using the block randomization method. Participants in the experimental group will first receive 8 sessions of diabetes coaching every 10 days after the chemistry interview. No intervention will be made to the control group. The preliminary implementation of the research will be carried out with 4 individuals with diabetes who voluntarily accept participation and meet the inclusion criteria. Data will be collected by face-to-face interview method. Data will be analyzed with IBM SPSS V23 program. conditions: Diabetes Mellitus, Type 2 studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Experimental and control group. primaryPurpose: PREVENTION masking: DOUBLE maskingDescription: When the researcher evaluates the participant according to the inclusion criteria, written consent will be obtained from the participant and pre-evaluation forms will be applied when compliance with the criteria is achieved. Afterwards, the participant's group will be notified to the researcher by the independent researcher and randomization will be carried out. With this; Data entries will be made by an independent researcher as group A and group B, without writing the group names. Until the data analysis and reporting is completed, the statistician will be blinded to which group is the intervention and which group is the control. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 64 type: ESTIMATED name: Diabetes coaching measure: Type 2 Diabetes Self-Management Scale measure: Diabetes Distress Scale measure: HbA1c Monitoring Form measure: Introductory Features Form sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06265168 id: req-2023-01512; am23Sutter3 briefTitle: Comprehensive Observations and Multidisciplinary Approaches in the Management of Unconscious Patients acronym: COMA overallStatus: RECRUITING date: 2024-03-01 date: 2026-12-31 date: 2026-12-31 date: 2024-02-20 date: 2024-04-11 name: University Hospital, Basel, Switzerland class: OTHER briefSummary: This prospective observational high-fidelity simulation study aims to observe and better understand how physicians from different disciplines differentiate in the management of a comatose patient and how their diagnostic and treatment approaches adhere to current recommendations in a highly standardized simulated scenario. The results gained by this study will give more insight into the current quality of diagnostic procedures and treatment and help refine recommendations in this context. The investigators hypothesize that physicians do not strictly adhere (regarding diagnostic approach and treatment) to current guidelines/recommendations when confronted with a comatose patient. conditions: Coma studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 30 type: ESTIMATED name: Simulation measure: To reveal diagnostic and treatment approaches of physicians from different disciplines when confronted with a comatose patient. measure: Physicians' grade of adherence to current recommendations regarding diagnostic procedures and treatment of a comatose patient measure: Participants' self-evaluation of their performance in hindsight sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: University Hospital Basel status: RECRUITING city: Basel country: Switzerland name: Prof. Dr. Sutter role: CONTACT name: Liliane Nueesch role: CONTACT lat: 47.55839 lon: 7.57327 hasResults: False
nctId: NCT06265155 id: SuzhouMHAnhui briefTitle: Triggers of Acute Ischemic Stroke Due to Large Vessel Occlusion overallStatus: RECRUITING date: 2024-02-01 date: 2025-06-30 date: 2025-12-31 date: 2024-02-20 date: 2024-03-28 name: Anzhi Li class: OTHER briefSummary: Acute ischemic stroke has a high incidence, ischemic stroke caused by large vessel occlusion is serious and has a poor prognosis, and its triggers in the short term before onset are not clear. The aim of this study was to evaluate the short-term risk of acute ischemic stroke caused by multiple triggers. In this trial, through a case-crossover study design, patients were asked about the exposure to each trigger in the previous year and the exposure during the preictal risk period (the exposure observed during the risk period) for each potential trigger of acute ischemic stroke caused by large vessel occlusion. To evaluate the relative risk of ischemic stroke resulting from exposure to triggers, comparing exposure during the dangerous period with the usual frequency of exposure. Relative risks and corresponding 95% CIs were estimated for past-year exposure and past-year mean exposure (assessed as chronic risk factors) and time to last exposure (assessed as triggers). Scientifically evaluate exposure to a range of potential triggers, including infection, mood, smoking, alcohol consumption, diarrhea and vomiting, extreme temperature changes, and several factors that increase blood pressure and their risk of developing acute ischemic stroke. conditions: Triggers of Acute Ischemic Stroke Due to Large Vessel Occlusion studyType: OBSERVATIONAL observationalModel: CASE_CROSSOVER timePerspective: PROSPECTIVE count: 302 type: ESTIMATED measure: RR values for exposure during the risk period versus exposure in the past year for each trigger sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Suzhou Hospital Anhui Medical University status: RECRUITING city: Suzhou state: Anhui zip: 234000 country: China name: Anzhi Li, B.S. role: CONTACT phone: +8615903860581 email: 365819805@qq.com name: Zhengfei Ma, M.D. role: CONTACT phone: 13866586362 email: Zhengfeima@126.com lat: 31.30408 lon: 120.59538 hasResults: False
nctId: NCT06265142 id: MoH/CSR/23/26368 briefTitle: Clean Catch Urine Feasibility and Contamination Rate Compared to Bladder Catheterization Urine in Pre-Continent Children overallStatus: NOT_YET_RECRUITING date: 2024-02-15 date: 2024-09-01 date: 2024-12-01 date: 2024-02-20 date: 2024-02-20 name: Oman Medical Speciality Board class: OTHER_GOV briefSummary: Introduction: Urinary tract infections (UTIs) are a common source of infection in children, accounting for a significant proportion of visits every year. Diagnosing UTIs requires obtaining a urine specimen, which can be collected using four methods: invasive techniques, such as suprapubic aspiration and urethral bladder catheterization, and noninvasive techniques, such as sterile bag and clean catch. However, catheterization can be a painful and invasive procedure, particularly in young infants who are less cooperative, and sometimes tends to be rejected by parents.
Outcome: Contamination rate and feasibility of both urine sampling techniques conditions: Urinary Tract Infections studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Patient will be assessed in triage and cases to be included in the study as per the inclusion criteria, after that patients will be randomized using computerized block randomization technique into two groups. Then, patients will be assigned to a bed, pulse oximetry to be applied, data collection sheet to be filled, confirm that infant had good feeding/ didn't pass urine over last 20 minutes and proper cleaning to be done. The next step will be, collecting urine sample according to randomization group. Group A patients (control group), urine to be collected by standardized catheterization technique while group B by standard CCU technique. Meanwhile, time of each procedure to be documented. Regarding group B , after collecting urine by CCU , we recommend to collect another sample by catheterization to guide the management and antibiotic choice. primaryPurpose: DIAGNOSTIC masking: SINGLE maskingDescription: The statistician who will analyze the data will be blinded. whoMasked: OUTCOMES_ASSESSOR count: 80 type: ESTIMATED name: Bladder catheterization name: clean catch urine via bladder massage technique measure: Urine culture contamination rate measure: Parental satisfaction questionnaire measure: duration of the procedure measure: Pain score sex: ALL minimumAge: 1 Day maximumAge: 6 Months stdAges: CHILD typeAbbrev: Prot hasProtocol: True hasSap: False hasIcf: False label: Study Protocol date: 2024-01-01 uploadDate: 2024-02-14T09:44 filename: Prot_000.pdf size: 662911 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2024-01-01 uploadDate: 2024-02-14T09:45 filename: ICF_001.pdf size: 128074 hasResults: False
nctId: NCT06265129 id: R.23.12.2429 briefTitle: The Association Between Obstructive Sleep Apnea Severity and Red Blood Cells Indices overallStatus: COMPLETED date: 2023-03-20 date: 2023-10-20 date: 2023-12-20 date: 2024-02-20 date: 2024-02-20 name: Mansoura University class: OTHER briefSummary: Obstructive sleep apnea syndrome (OSAS) is characterized by recurrent episodes of obstructive events (apnea and hypopnea) and intermittent hypoxia, which in turn contributes to the systemic inflammation that underlies this disease and its consequences (Ryan et al 2009, Gileles-Hillel et al 2014). This systemic inflammation leads to endothelial dysfunction, which contributes to the pathogenesis of cardiovascular complications in OSAS, in addition to the exposure to risk factors, such as male gender, older age, obesity, and lack of exercise (Lorenzi Filho et al 2010). Some red blood cells (RBC) and platelets indices have emerged as inflammatory biomarkers in various diseases (Tertemiz et al 2016) The severity of OSA is significantly associated with increase hematocrit, even after controlling for possible confounding variables. However, nocturnal hypoxemia in OSA does not usually lead to clinical polycythemia (Choi et al 2006). In patients referred with a clinical diagnosis of OSAS, RDW may be a marker for the severity of the condition. As RDW is usually included in a complete blood count, it could provide an inexpensive tool for triaging OSAS patients for polysomnography evaluation (Sökücü et al 2012). The hematological indices white blood cell count (WBC), neutrophil count, lymphocyte count, mean platelet volume (MPV), platelet distribution width (PDW), and red blood cell distribution width (RDW) have been proposed as alternative markers to those normally used clinically, e.g., interleukin-6 (IL6) and C-reactive protein, to evaluate the burden of inflammation in OSAS (Wu et al 2018) conditions: Obstructive Sleep Apnea studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 30 type: ACTUAL name: Complete blood picture (done in the morning after the night of monitored sleep by PSG. With stress on red blood cell indices (RBC count, MCV, MCH, RDW) measure: Red Blood Cells Indices sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Tamer Awad Elsayed city: Mansoura state: Dakhlia zip: 050 country: Egypt lat: 31.03637 lon: 31.38069 hasResults: False
nctId: NCT06265116 id: A0801024 CD briefTitle: One-Step Universal Adhesives: A 3-year Clinical Trial in Class II Composite Restorations overallStatus: RECRUITING date: 2024-01-23 date: 2027-01-23 date: 2027-01-30 date: 2024-02-20 date: 2024-02-20 name: Mansoura University class: OTHER briefSummary: to evaluate and compare the clinical performance and periodontal responses of four commercially available one-step universal adhesives with different formulations in Class II composite restorations over a three-year period. conditions: Dental Caries Class II conditions: Marginal Integrity of Composite Restorations With Universal Adhesives studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 48 type: ESTIMATED name: One-step universal adhesive measure: Percentage of functional and biological properties for each group sex: ALL minimumAge: 20 Years maximumAge: 40 Years stdAges: ADULT facility: Omar Abd El-Fattah Abd El-Maksoud status: RECRUITING city: Mansoura state: Dakahlia zip: 35516 country: Egypt name: Omar A Abd El-Maksoud role: CONTACT phone: 01024366555 email: omarabdelfata7.92@gmail.com lat: 31.03637 lon: 31.38069 hasResults: False
nctId: NCT06265103 id: 20190407 briefTitle: Epilepsy Learning Healthcare System (ELHS) acronym: ELHS overallStatus: RECRUITING date: 2019-03-20 date: 2099-02-14 date: 2099-02-14 date: 2024-02-20 date: 2024-02-20 name: Epilepsy Foundation of America class: OTHER briefSummary: The Epilepsy Learning Health System (ELHS) is a quality improvement and research network to improve outcomes for people with epilepsy. The ELHS is designed as a model of value-based chronic care for epilepsy as envisioned by the National Academies of Medicine Committee in their landmark reports "The Learning Health System" and "Epilepsy Across the Spectrum: Promoting Health and Understanding".
nctId: NCT06265090 id: F.P.T 2307017 briefTitle: Effect of Lumbar Stabilization Exercises Combined With Ball and Balloon Exercise in Treatment of Chronic Non-specific Low Back Pain overallStatus: COMPLETED date: 2022-01-10 date: 2022-12-20 date: 2023-01-10 date: 2024-02-20 date: 2024-02-20 name: Delta University for Science and Technology class: OTHER briefSummary: \[Background\] Low back pain occurs when a poor lifestyle weakens the muscular strength of the waist and excessive loads on and tensions of the muscles create pain. Mediating muscle weakening to stabilize the trunk is an important aspect in the recovery of body function in patients with LBP \[Purpose\], this study was conducted to investigate the effect of core stability exercises combined with ball and balloon exercises on chronic non-specific low back pain. \[Subjects and Methods\] a sixty patient of chronic non-specific low back pain were randomly assigned into two groups, group (A) received core stability exercises combined with ball and balloon exercises and group (B) received core stability exercises, these exercises were performed for three times a week for four weeks. Pain was assessed by visual analogue scale (VAS). Spinal function was measured by Arabic Oswestery Disability Index (AODI) and pulmonary function was assessed by pulmonary function test including forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), FEV1/FVC, maximum voluntary ventilation (MVV) and peak expiratory flow (PEF) before and after the study.
Keywords: core stability exercises, ball and balloon exercises, chronic non-specific low back pain conditions: Chronic Mechanical Low Back Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: This randomized controlled experimental trial was carried out at the outpatient clinic of faculty of physical therapy, Delta University for science and technology from April 2023 to October 2023. The aims of the study and the study protocol were explained for each patient before participation in the study. All patients signed an approved informed consent form for participation in this study. Before starting the treatment program, a complete history and physical examination will be taken for all patients.
The local ethics committee approved this study (Delta University for science and technology, faculty of Physical Therapy, Ethics committee F.P.T 2307017). primaryPurpose: TREATMENT masking: TRIPLE maskingDescription: the participants were selected randomly without their knowledge about in experimental or control group the assessor was for assessment only and the therapist was for treatment only whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 60 type: ACTUAL name: therapeutic exercises name: exercises measure: visual analogue score measure: forced expiratory volume in the first second (FEV1) in liters measure: forced vital capacity (FVC) in liters measure: FVC/FEV1 ratio measure: maximum voluntary ventilation (MVV) measure: peak expiratory flow (PEF) in liter/min measure: Arabic Oswestery Disability Index (AODI) for functional assessment measure: weight measure: age measure: height sex: ALL minimumAge: 18 Years maximumAge: 25 Years stdAges: ADULT facility: Delta University For Science and Technology city: Al Manşūrah state: Gamasah zip: 11152 country: Egypt lat: 31.03637 lon: 31.38069 hasResults: False
nctId: NCT06265077 id: 2023-199 briefTitle: Novel Preventive Approach Against Filgrastim-Induced Bone Pain in Cancer Patients overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2024-08 date: 2024-08 date: 2024-02-20 date: 2024-02-20 name: Noha Mansour class: OTHER briefSummary: No randomized controlled trial evaluated the safety and efficacy of double blockade on G-CSF induced bone pain. Therefore, this study aims to evaluate the efficacy and safety of double blockade on the incidence and severity of G-CSF induced bone pain. conditions: Breast Cancer conditions: Filgrastim Adverse Reaction studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: DOUBLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 60 type: ESTIMATED name: Placebo name: famotidine and loratadine measure: The incidence of grade 2 or 3 bone pain in cycle 1 according to Common Terminology Criteria for Adverse Events sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06265064 id: KhonKaenUniversity briefTitle: STOP-Bang Score and Factors Predicting Difficult Intubation for Prediction of Difficult Mask Ventilation in Obese Patients overallStatus: COMPLETED date: 2022-07-11 date: 2023-10-31 date: 2023-10-31 date: 2024-02-20 date: 2024-02-20 name: Khon Kaen University class: OTHER briefSummary: The goal of this prospective observational study is to test combination of STOP-Bang score and factors predicting difficult intubation can improve accuracy of prediction difficult mask ventilation in obese patients that undergoing to elective surgery under general anesthesia.
Researchers will compare obese patients with/without high STOP bang score \>=3 point plus factor predicting difficult intubation (Mallampati grade 3-4, Neck circumference \> 42 cm, Thyromental distance \< 6 cm)to prediction difficult mask ventilation conditions: Obesity conditions: OSA studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 278 type: ACTUAL name: STOP-Bang score >= 3 with factors predicting difficult intubation measure: Difficult mask ventilation measure: Resipiratory complication sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: KhonKaen University city: Nai Muang state: Khonkaen zip: +66 country: Thailand lat: 15.17901 lon: 100.1282 hasResults: False
nctId: NCT06265038 id: SANAT-CAGE-2022 briefTitle: Confirmatory Investigation to Evaluate the Performance and Safety of ReSpace TiCell Cage Implants in TLIF overallStatus: RECRUITING date: 2024-02-01 date: 2026-02-01 date: 2026-10-01 date: 2024-02-20 date: 2024-02-21 name: Sanatmetal Orthopaedic and Traumatologic Equipment Manufacturer Ltd. class: INDUSTRY briefSummary: The primary objective of this study is to confirm superiority for the efficacy of the ReSpace Ticell Cage implants in Transforaminal Lumbar Interbody Fusion compared to state-of-the-art.
* To evaluate if using the device can be considered as safe overall. conditions: Degenerative Instability conditions: Spondylolisthesis conditions: Post-discectomy Syndrome conditions: Post-traumatic Instability studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Prospective, single-arm, open-label clinical trial. This clinical investigation addresses to collect data on clinical performance, effectiveness and safety of Sanatmetál's ReSpace TiCell Cage in human subjects following the good clinical practice according to the Medical Device Regulation (MDR) \& EN ISO 14155:2020. The study is conducted in Hungary at National Center for Spinal Disorders. primaryPurpose: OTHER masking: NONE count: 99 type: ESTIMATED name: ReSpace TiCell Cage measure: CT imaging_1 - cumulative fusion rate measure: CT imaging_2 - fusion status measure: Visual Analog Scale measure: Oswestry Disability Index (ODI) measure: AE and ADE measure: Complications measure: Surgical revisions sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: National Center for Spinal Disorders status: RECRUITING city: Budapest state: Pest zip: 1126 country: Hungary name: Aron Lazary, MD, PhD role: CONTACT phone: +36118877900 phoneExt: 5671 email: lazary.aron@gmail.com lat: 47.49801 lon: 19.03991 hasResults: False
nctId: NCT06265025 id: GM103-CT-101 briefTitle: GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors overallStatus: RECRUITING date: 2024-02-20 date: 2025-05-30 date: 2028-10-30 date: 2024-02-20 date: 2024-03-21 name: GeneMedicine Co., Ltd. class: INDUSTRY briefSummary: The purpose of this study is to measure safety, tolerability, and preliminary antitumor efficacy of GM103 administered alone and in combination with pembrolizumab in patients with locally advanced, unresectable, refractory and/or metastatic solid tumors (including but not limited to head and neck cancer, malignant melanoma, CRC, renal cell carcinoma, cervical cancer, and breast cancer). Study details include: conditions: Head and Neck Cancer conditions: Malignant Melanoma conditions: Colorectal Cancer conditions: Renal Cell Carcinoma conditions: Cervical Cancer conditions: Breast Cancer studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: Dose escalation and dose expansion primaryPurpose: TREATMENT masking: NONE count: 125 type: ESTIMATED name: GM103 (Part A) name: GM103 (Part B) name: GM103 and Pembrolizumab (Part C) measure: Percentage of patients with DLTs by cohorts measure: Percentage of patients with DLTs measure: Incidence of AEs, AESIs, SAEs, AEs leading to discontinuation, and AEs resulting in death measure: ORR measure: DCR defined as the proportion of patients whose BOR was CR, PR and SD measure: Median PFS defined as the time from the date of the first administration of study drug to the date of disease progression or death measure: Incidence of GM103 detection measure: Changes in the level of anti-adenovirus antibodies(ADA) in blood compared to baseline (ADA in genome copies/mL using qPCR) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: National Cancer Center status: NOT_YET_RECRUITING city: Goyang-si state: Gyeonggi-do zip: 10408 country: Korea, Republic of name: WY Choi role: CONTACT lat: 37.65639 lon: 126.835 facility: Korea University Anam Hospital status: NOT_YET_RECRUITING city: Seoul zip: 02841 country: Korea, Republic of name: SH Lee role: CONTACT lat: 37.566 lon: 126.9784 facility: Hanyang University Seoul Hospital status: NOT_YET_RECRUITING city: Seoul zip: 04763 country: Korea, Republic of name: MS Chung role: CONTACT lat: 37.566 lon: 126.9784 facility: Severance Hospital, Yonsei University Health System status: RECRUITING city: Seoul country: Korea, Republic of name: JY Lee role: CONTACT lat: 37.566 lon: 126.9784 hasResults: False
nctId: NCT06265012 id: PHV01-C-101 briefTitle: Study to Evaluate the Recombinant Vesicular Stomatitis Virus (rVSV)-Marburg Virus Vaccine Candidate (PHV01) in Healthy Adult Subjects acronym: PHV01 overallStatus: RECRUITING date: 2024-02-05 date: 2024-04-17 date: 2024-09-16 date: 2024-02-20 date: 2024-02-22 name: Public Health Vaccines LLC class: INDUSTRY name: Biomedical Advanced Research and Development Authority briefSummary: This is a Phase 1 randomized, single-blind, placebo-controlled, ascending dose study to evaluate the safety and immunogenicity of rVSV∆G-MARV-GP \[Angola\] (PHV01, Marburg Virus glycoprotein \[MARV GP\] Vaccine) in healthy adults. PHV01 is a live, attenuated rVSV vaccine expressing the MARV GP. The main questions it aims to answer are: