hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06344013 id: 29BRC24.0034 - BUNDLE ABCDEF briefTitle: The ABCDEF Bundle in Critical Care: a French National Survey Still a Long Way to go! overallStatus: COMPLETED date: 2022-07-01 date: 2022-07-31 date: 2022-07-31 date: 2024-04-03 date: 2024-04-03 name: University Hospital, Brest class: OTHER briefSummary: The goal of this observational study is to evaluate the knowledge and compliance of French intensive care units with the ABCDEF (A: Assessment, Prevention, Management of Pain, B: Both Spontaneous Awakening Trials and Spontaneous Breathing Trials, C: Choice of Sedation and Analgesia, D: Delirium Assessment, Prevention, and Management, E: Early Mobility and Exercise, F: Family Engagement and Empowerment) bundle. French ICU doctors will be asked to answer a questionnaire available online. conditions: Delirium studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 341 type: ACTUAL measure: knowledge and compliance of French intensive care units with the ABCDEF sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Chu Brest city: Brest zip: 29609 country: France lat: 48.3903 lon: -4.48628 hasResults: False
nctId: NCT06344000 id: RICU20240323 briefTitle: Study on Disease Progression and Nutritional Status in Bronchiectasis overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2027-04-15 date: 2027-04-15 date: 2024-04-03 date: 2024-04-03 name: Wuhan Union Hospital, China class: OTHER briefSummary: Bronchiectasis is a common lung disease. The Bronchiectasis Severity Index (BSI) is a widely used assessment system. The body mass index (BMI) is a commonly used measure of nutritional status, but it has its limitations. To provide a more comprehensive assessment, the investigators also consider other nutrition-related indices such as upper arm circumference, calf circumference, skinfold thickness and grip strength. The investigators will specify the relationship between nutritional status and disease progression by measuring nutrition-related indicators and tracking participants' disease progression. conditions: Bronchiectasis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 300 type: ESTIMATED name: inapplicable measure: Frequency of acute exacerbations of bronchiectasis measure: Deterioration of lung function measure: Severity of dyspnoea measure: Bhalla scores on CT of participants' lungs measure: Frequency of hospitalisation measure: Death sex: ALL minimumAge: 18 Years maximumAge: 100 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Wuhan Union Hospital city: Wuhan state: Hubei zip: 430022 country: China name: Xiaorong Wang role: CONTACT phone: 18627195231 phoneExt: +86 email: rong-100@163.com lat: 30.58333 lon: 114.26667 hasResults: False
nctId: NCT06343987 id: 1-10-72-165-23 briefTitle: The FEMA Study: Feasibility of Exercise in Patients With Metastatic Breast Cancer and Adiposity overallStatus: RECRUITING date: 2024-02-19 date: 2024-12 date: 2025-03 date: 2024-04-03 date: 2024-04-09 name: Aarhus University Hospital class: OTHER name: Danish Cancer Society briefSummary: The goal of this clinical trial is to test a physical activity program in patients with metastatic breast cancer and overweight receiving endocrine-based treatment.
Participants will randomized 2:1 to either a physical activity program or care as usual. conditions: Metastatic Breast Cancer conditions: Estrogen-receptor-positive Breast Cancer conditions: Adiposity studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Continuous inclusion. Randomized 2:1 - intervention group and observational group, respectively. primaryPurpose: TREATMENT masking: NONE count: 21 type: ESTIMATED name: Physical Activity measure: Adherence as assessed by attendance rate measure: Metabolic efficacy assessed by change in metabolic score measure: Perceived satisfaction assessed by qualitative interviews measure: Health-related quality of life as assessed by EORTC-QLQ-30 measure: Cancer coping as assessed by CBI-12 measure: Sleep quality as assessed by PSQI measure: Insomnia as assessed by ISI measure: Change in C-reactive protein measure: Change in leukocytes measure: Change in HbA1c measure: Change in LDL cholesterol measure: Change in HDL cholesterol measure: Change in BMI measure: Fat mass measure: Muscle mass measure: Visceral fat measure: VO2 max measure: Handgrip strength measure: Sit-rising sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Oncology, Aarhus University Hospital status: RECRUITING city: Aarhus N state: Central Denmark Region zip: 8200 country: Denmark name: Signe Borgquist, MD, PhD role: CONTACT phone: + 45 22 62 45 25 email: signe.borgquist@auh.rm.dk name: May W Nielsen, Bsc.Med. role: CONTACT phone: +45 29 90 66 05 email: maywni@gmail.com lat: 56.15674 lon: 10.21076 hasResults: False
nctId: NCT06343974 id: 0843 briefTitle: Noninvasive Evaluation of Fetal Hyperinsulinemia With Ultrasound Radiomics overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-12-31 date: 2026-05-01 date: 2024-04-03 date: 2024-04-03 name: Turku University Hospital class: OTHER_GOV briefSummary: The goal of this observational study is to compare fetal liver ultrasound radiomics between pregnancies complicated by type 1 diabetes and healthy controls.
Participants will undergo ultrasound examination to collect ultrasound data for the analyses. conditions: Pregnancy in Diabetic conditions: Diabetes Mellitus, Type 1 studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 60 type: ESTIMATED measure: Fetal liver ultrasound texture measure: Birth weight in grams measure: Birth weight centile measure: Large for gestational age (LGA) measure: Interventricular septum (IVS) width measure: Number of pregnancies with neonatal hypoglycemia measure: Rate of neonatal hypoglycemia treated with oral dextrose gel measure: Rate of neonatal hypoglycemia treated with intravenous (IV) glucose measure: Length of treatment for neonatal hypoglycemia measure: Number of neonates admitted to neonatal intensive care unit (NICU) measure: Length of NICU admission measure: Number of pregnancies with neonatal respiratory complications related to maternal diabetes measure: Number of pregnancies with neonatal hyperbilirubinemia measure: Maternal HbA1c concentration measure: Glucose management indicator (GMI) measure: Time in glycemic range (TIR) measure: Time above glucose range measure: Time below glucose range sex: FEMALE minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Turku University Hospital city: Turku country: Finland lat: 60.45148 lon: 22.26869 hasResults: False
nctId: NCT06343961 id: 2024-76 briefTitle: Intraoperative Application of Fluorescein Sodium Angiography in Vascular Retinopathy overallStatus: NOT_YET_RECRUITING date: 2024-04-18 date: 2025-12 date: 2025-12 date: 2024-04-03 date: 2024-04-03 name: Jie Zhong class: OTHER briefSummary: The study used a new surgical technique: intraoperative fluorescence imaging,In the 1980s, some scholars proposed the concept of intraoperative fluorescein angiography.During vitrectomy, intraoperative fluorescein angiography under 3D microscope can guide the surgeon to observe the non-perfusion area and new blood vessels on the same screen for accurate retinal photocoagulation therapy.Through this technology, the primary retinal disease can be identified in time after the removal of vitreous hemorrhage during surgery, providing effective imaging evidence support for the design of further treatment. conditions: Vascular Retinopathy of Left Eye (Disorder) conditions: Vascular Retinopathy of Right Eye (Disorder) conditions: Diabetic Retinopathy conditions: Retinal Vein Occlusion conditions: Retinal Vasculitis conditions: Vitreous Hemorrhage studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A total of 80 patients with vitreous hemorrhage diagnosed in Sichuan Provincial People's Hospital from January 2024 to December 2025 were selected. The number of included cases was calculated according to the minimum sample size of 200 patients with vitreous hemorrhage in our hospital, 95% confidence level and 5% confidence interval, and the calculated result was 79. The included cases were equally divided by random number method. 40 patients in the control group were given vitrectomy and other conventional operations such as retinal laser photocoagulation. In contrast group, 40 patients were given vitrectomy combined with intraoperative fluorescein angiography and other conventional operations such as retinal laser photocoagulation. The diagnosis rate of primary disease cause, observation rate of neovascularization and non-perfusion area, visual acuity, visual field, thickness of macular fovea and postoperative complications (ciliary detachment, secondary vitreous hemorrhage, neovascu primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 80 type: ESTIMATED name: Intraoperative Fluorescein Angiography measure: best corrected visual acuity measure: Central retinal thickness sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06343948 id: BL-B01D1-306 briefTitle: A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Unresectable Locally Advanced, Recurrent, or Metastatic HR+HER2- Breast Cancer overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-05 date: 2026-05 date: 2024-04-03 date: 2024-04-04 name: Sichuan Baili Pharmaceutical Co., Ltd. class: INDUSTRY name: Baili-Bio (Chengdu) Pharmaceutical Co., Ltd. briefSummary: This trial is a registered phase III, randomized, open-label, multicenter study to evaluate the efficacy and safety of BL-B01D1 in patients with unresectable locally advanced, recurrent, or metastatic HR+HER2- breast cancer after failure of at least one prior line of chemotherapy. conditions: HR+HER2- Breast Cancer studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 382 type: ESTIMATED name: BL-B01D1 name: Eribulin name: Vinorelbine name: Gemcitabine name: Capecitabine measure: Progression-free survival (PFS) measure: Overall survival (OS) measure: Objective Response Rate (ORR) measure: Disease Control Rate (DCR) measure: Duration of Response (DOR) measure: Treatment Emergent Adverse Event (TEAE) measure: Anti-drug antibody (ADA) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Cancer Hospital Chinese Academy of Medical Sciences city: Beijing state: Beijing country: China name: Binghe Xu role: CONTACT lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06343935 id: YY-20394-014 briefTitle: A National Multicenter, Real-world Study of Linperlisib in the Treatment of Lymphoma overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2024-04-30 date: 2025-04-30 date: 2024-04-03 date: 2024-04-03 name: Shanghai YingLi Pharmaceutical Co. Ltd. class: INDUSTRY briefSummary: This is a national multicenter, randomized controlled, open, dose-optimized Phase IV study. It is expected to enroll approximately 88 patients with relapsed/refractory indolent B-cell lymphoma. The aim is to evaluate the efficacy and safety of linperlisib in the treatment of patients with relapsed/refractory indolent B-cell lymphoma at two doses/modes of administration (clinically recommended dose/mode and optimized dose/mode). conditions: Indolent B-cell Lymphoma studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 88 type: ESTIMATED name: Linperlisib measure: Progression free survival measure: Objective response rate measure: Overall survival measure: Adverse event measure: Serious adverse event sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06343909 id: REC/RCR & AHS/23/0197Ayesha briefTitle: Foot and Hip Abductor Strengthening in Patients With Knee Osteoarthritis. overallStatus: RECRUITING date: 2023-11-23 date: 2024-06-01 date: 2024-06-01 date: 2024-04-03 date: 2024-04-03 name: Riphah International University class: OTHER briefSummary: The study will be Randomized controlled trail, Subject diagnosed with knee osteoarthritis meeting predetermined inclusion and exclusion criteria will be divided into two groups.
Pre assessment will be done using pain, ROM, function, foot arches and knee alignment as subjective measurement through KOOS questionnaire, goniometer, 2D frontal plane projection, Berkemann foot prints using ink and paper ,30s chair stand test, nine step stair climb,40m fast paced walk test,Global rating of change score respectively . One group will be treated with hip abductor strengthening exercise along with conventional exercises and second group will be treated with intrinsic foot muscle strengthening exercise along with conventional exercises. Post treatment values recorded after the session.After data collection from defined study setting,data will be entered and analyzed at Riphah International University,Lahore conditions: Knee Osteoarthritis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 30 type: ESTIMATED name: Hip abductor strengthening exercise name: Intrinsic foot muscle strengthening along with conventional exercises measure: Knee Osteoarthritis Outcome Score (KOOS) measure: Berkemann foot prints measure: Frontal plane projection measure: Goniometer measure: 30 seconds chair stand test measure: Overall self-perception by Global Rating of Change Score measure: 9 step stairs climb test. measure: 40-m fast-paced walk test sex: ALL minimumAge: 40 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: THQ hospital KRK. status: RECRUITING city: Lahore state: Punjab country: Pakistan name: Ayesha Anwar, DPT role: CONTACT phone: 03340003448 email: ayeshaanwarali123@gmail.com lat: 31.558 lon: 74.35071 hasResults: False
nctId: NCT06343896 id: AnkaraCHBilkent-tntaygurt briefTitle: Evaluation of Sedation Depth and Reliability With Integrated Pulmonary Index (IPI) Follow-up in Pediatric Radiological Interventions acronym: IPI overallStatus: RECRUITING date: 2024-04-01 date: 2024-06-15 date: 2024-10-15 date: 2024-04-03 date: 2024-04-05 name: Ankara City Hospital Bilkent class: OTHER briefSummary: In this study, we aimed to investigate the predictability of possible respiratory complications and the effect of the addition of the integrated pulmonary (EPI) score to the evaluation of the patient's respiratory index status in addition to the SPO2 measurement available in standard ASA monitoring in pediatric patients undergoing interventional radiological procedures under sedoanesthesia. conditions: Sedation conditions: BIS conditions: Integrated Pulmonary Index studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 68 type: ESTIMATED name: monitorization reliability measure: EVALUATION OF IPI RELIABILITY IN PEDIATRIC PATIENTS measure: BİS correlation with the IPI measure: pulse oximetry correlation with the IPI measure: noninvasive blood pressure measure: heart rate measure: respiratory rate measure: end tidal carbondioxide measure: apnea and hypoxia conditions that develop in the patient during anesthesia measure: postoperative recovery time measure: intraoperative total dose of medication used measure: postoperative nausea and vomiting sex: ALL minimumAge: 2 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Ankara City Hospital, Bilkent status: RECRUITING city: Ankara country: Turkey name: tugbanur taygurt role: CONTACT phone: +905322005632 email: tugbanurtaygurt@gmail.com lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06343883 id: 24-353 briefTitle: Investigation of Low-intensity Focused Ultrasound Pressure overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-07 date: 2026-07 date: 2024-04-03 date: 2024-04-03 name: Virginia Polytechnic Institute and State University class: OTHER briefSummary: Investigating the relationship between input pressure of low-intensity focused ultrasound and an evoked potential in both eeg and fMRI. conditions: Somatic Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: Primary cohort (safety) will be collected prior to full study collection. Primary collection will involve highest pressure application and follow-up safety scans (MRI) to be reviewed by a Neuroradiologist. Once cleared - parallel design will be utilized for eeg and fMRI cohorts. Both cohorts will receive 3 LIFU pressures randomized over 3 study visits. Electrical stimulations will be applied pre and post LIFU administration to induce somatosensory evoked potentials (SEPs). primaryPurpose: BASIC_SCIENCE masking: NONE maskingDescription: No masking, no sham. All subjects will receive all conditions, all of which are active. count: 25 type: ESTIMATED name: low-intensity focused ultrasound - low pressure name: low-intensity focused ultrasound - medium pressure name: low-intensity focused ultrasound - high pressure measure: Report of Symptoms Questionnaire measure: MRI measure: EEG measure: fMRI sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fralin Biomedical Research Institute at VTC city: Roanoke state: Virginia zip: 24016 country: United States name: Jessica Florig, MPH role: CONTACT phone: 540-526-2261 email: jnw@vtc.vt.edu name: Wynn Legon, PhD role: PRINCIPAL_INVESTIGATOR lat: 37.27097 lon: -79.94143 hasResults: False
nctId: NCT06343870 id: ESTIME briefTitle: Estradiol and Testosterone Subdermal Implants for Menopause Treatment (ESTIME) acronym: ESTIME overallStatus: NOT_YET_RECRUITING date: 2024-05-31 date: 2025-01-31 date: 2025-04-30 date: 2024-04-03 date: 2024-04-03 name: University of Sao Paulo General Hospital class: OTHER briefSummary: Estrogen and androgen deficiencies negatively impact the quality of life of women at different stages of life, especially after menopause. New modalities and new therapeutic alternatives have been researched. Parenteral administration of estradiol and testosterone could be effective to treat symptoms secondary to estrogen and androgen deficiencies and minimize these adverse events. This study evaluates the efficiency of subdermal implant-bioabsorbable use in women with menopausal symptoms associated with secondary estrogen and androgen deficiencies in women with natural menopause, premature ovarian failure or surgical menopause due to cervical cancer. Pharmacokinetic, biochemical, metabolic, thromboembolic and hormonal data will be evaluated, as well as the effects on quality of life, menopausal symptoms and sexual function after treatment. conditions: Menopause conditions: Testosterone Deficiency conditions: Estrogen Deficiency studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Parallel Assignment primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 140 type: ESTIMATED name: testosterone pellet (100 mg) name: Placebo measure: Evaluate hormonal, metabolic thromboembolic and clinical effects on climacteric symptoms measure: Evaluate response in quality of life and sexual function sex: FEMALE minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT hasResults: False
nctId: NCT06343857 id: CE-AVEC 878/2022/Oss/AOUFe briefTitle: Joint Self-Assessment Forms for Knee, Ankle and Shoulder overallStatus: ACTIVE_NOT_RECRUITING date: 2023-05-01 date: 2024-04-30 date: 2024-04-30 date: 2024-04-03 date: 2024-04-03 name: University Hospital of Ferrara class: OTHER briefSummary: The present study represents the pilot phase of the project aimed at developing anatomical site-specific self-assessment questionnaires (shoulder, knee and ankle) that can advise the subject of the need for an orthopaedic specialist examination.
The data collected from the questionnaires will be used to evaluate the statistical significance (p value) of each question in the questionnaire in relation to the outcome of the orthopaedic specialist visit. Through a multivariate logistic analysis of the answers given by the subject, it will be possible to 'weight' each answer to obtain a final value that gives an indication of an orthopaedic specialist visit. conditions: Osteoarthritis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 150 type: ESTIMATED name: self-assessment questionnaire measure: Observation of the distribution of questionnaire responses for each anatomical site. measure: Therapeutic indication of the orthopaedic specialist for each subject participating in the study sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS Istituto Ortopedico Rizzoli, Clinica Ortopedica e Traumatologica II city: Bologna state: BO country: Italy lat: 44.49381 lon: 11.33875 facility: Unità Operativa di Chirurgia della Spalla I.R.C.C.S. Ospedale Galeazzi-Sant'Ambrogio city: Milan state: MI country: Italy lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06343844 id: 49RC23_0070 briefTitle: Disparities in Myocardial Infarction Remodeling According to Gender acronym: REMOVE 2 overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2039-09-01 date: 2040-07-01 date: 2024-04-03 date: 2024-04-03 name: University Hospital, Angers class: OTHER_GOV briefSummary: Following myocardial infarction, female individuals demonstrate a poorer prognosis, characterized by elevated rates of mortality and heart failure. A primary hypothesis suggests unfavorable cardiac remodeling in women. This remodeling, defined as alterations in cardiac size and shape post-infarction, necessitates repeated non-invasive imaging for study. conditions: Myocardial Infarction conditions: Ventricular Remodeling studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 1650 type: ESTIMATED name: cardiac imaging to assess left ventricular volumes and function measure: Asses left ventricular remodeling disparities between genders measure: Evaluate the evolution of remodeling at Month 3 measure: Assess remodeling changes between inclusion and Month 12 measure: Assess the prevalence of comorbidities and their impact on the effect on the outcome: post-infarction cardiac remodeling with gender (cardiovascular risk factors, renal function, hepatic functionperipheral artery disease, way of life) measure: Explore prognostic disparities between men and women. measure: Evaluate lifestyle habits up to 10 years: outcome anxiety/depression measure: Evaluate lifestyle habits up to 10 years: outcome diet score measure: Evaluate lifestyle habits up to 10 years: outcome physical activity measure: Assess the risk of remodeling based on specific parameters in female subjects: presence of endometriosis measure: Assess the risk of remodeling based on specific parameters in female subjects: presence of polycystic ovary measure: Assess the risk of remodeling based on specific parameters in female subjects: presence of uterine fibroma measure: Assess the risk of remodeling based on specific parameters in female subjects: presence of hormonal therapy measure: Assess the risk of remodeling based on specific parameters in female subjects: date of first period measure: Assess the risk of remodeling based on specific parameters in female subjects: pregnancy measure: Assess the risk of remodeling based on specific parameters in female subjects: children measure: Assess the risk of remodeling based on specific parameters in female subjects: obstetrical event measure: Assess the risk of remodeling based on specific parameters in female subjects: menopause sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False