The objective of the present trial is to determine whether remote ischemic conditioning performed early after out-of-hospital cardiac arrest can decrease mortality, or multiple organ failure and/or severe neurological failure. conditions: Out-Of-Hospital Cardiac Arrest studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 220 type: ESTIMATED name: Remote ischemic conditioning name: No remote ischemic conditioning measure: All cause of death measure: Multiple organ failure measure: Severe neurological failure measure: Sepsis-related Organ Failure Assessment (SOFA) score measure: Sepsis-related Organ Failure Assessment (SOFA) score measure: Sepsis-related Organ Failure Assessment (SOFA) score measure: Sepsis-related Organ Failure Assessment (SOFA) score after exclusion of the neurological sub-score measure: Sepsis-related Organ Failure Assessment (SOFA) score after exclusion of the neurological sub-score measure: Sepsis-related Organ Failure Assessment (SOFA) score after exclusion of the neurological sub-score measure: Sepsis-related Organ Failure Assessment (SOFA) sub-scores for each organ dysfunction measure: Sepsis-related Organ Failure Assessment (SOFA) sub-scores for each organ dysfunction measure: Sepsis-related Organ Failure Assessment (SOFA) sub-scores for each organ dysfunction measure: Mean Sepsis-related Organ Failure Assessment (SOFA) score measure: Mean Sepsis-related Organ Failure Assessment (SOFA) score after exclusion of the neurological sub-score measure: Variations of the Sepsis-related Organ Failure Assessment (SOFA) score (delta-SOFA) measure: Variations of the Sepsis-related Organ Failure Assessment (SOFA) score (delta-SOFA) after exclusion of the neurological sub-score measure: Serum level of neuron-specific enolase (NSE) measure: Cerebral Performance Categories (CPC) scale measure: All-cause mortality sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hôpital Louis Pradel city: Bron zip: 69500 country: France name: Thomas BOCHATON role: CONTACT phone: 04 72 35 75 41 phoneExt: +33 email: thomas.bochaton@chu-lyon.fr name: Thomas BOCHATON role: PRINCIPAL_INVESTIGATOR lat: 45.73333 lon: 4.91667 facility: Hôpital Gabriel Montpied, CHU de Clermont Ferrand city: Clermont-Ferrand zip: 63000 country: France name: François THOUY role: CONTACT phone: 04 73 75 07 50 phoneExt: +33 email: fthouy@chu-clermontferrand.fr name: François THOUY role: PRINCIPAL_INVESTIGATOR lat: 45.77966 lon: 3.08628 facility: Centre Jean Perrin, Clermont-Ferrand city: Clermont-Ferrand zip: 69300 country: France name: Alexandre LAUTRETTE role: CONTACT phone: 04 73 27 80 80 phoneExt: +33 email: alautrette@chu-clermontferrand.fr name: Alexandre LAUTRETTE role: PRINCIPAL_INVESTIGATOR lat: 45.77966 lon: 3.08628 facility: Hôpital F Mitterrand, CHU de Dijon city: Dijon zip: 21079 country: France name: Jean-Pierre QUENOT role: CONTACT phone: 03 80 29 37 51 phoneExt: +33 email: jean-pierre.quenot@chu-dijon.fr name: Jean-Pierre QUENOT role: PRINCIPAL_INVESTIGATOR lat: 47.31667 lon: 5.01667 facility: Hôpital Albert Michallon, CHU de Grenoble city: La Tronche zip: 38700 country: France name: Carole SCHWEBEL role: CONTACT phone: 04 76 76 87 79 phoneExt: +33 email: cschwebel@chu-grenoble.fr name: Carole SCHWEBEL role: PRINCIPAL_INVESTIGATOR lat: 45.20429 lon: 5.73645 facility: Hôpital Edouard Herriot city: Lyon zip: 69003 country: France name: Marie-Line HARLAY role: CONTACT phone: 04 72 11 28 62 phoneExt: +33 email: marie-line.harlay@chu-lyon.fr name: Laurent ARGAUD role: CONTACT phone: 04 72 11 28 62 phoneExt: +33 email: laurent.argaud@chu-lyon.fr name: Marie-Line HARLAY role: PRINCIPAL_INVESTIGATOR name: Laurent ARGAUD role: SUB_INVESTIGATOR name: Martin COUR role: SUB_INVESTIGATOR lat: 45.74848 lon: 4.84669 facility: Hôpital Saint-Joseph Saint-Luc city: Lyon zip: 69007 country: France name: Emmanuel VIVIER role: CONTACT phone: 04 78 61 82 09 phoneExt: +33 email: evivier@ch-stjosephstluc-lyon.fr name: Emmanuel VIVIER role: PRINCIPAL_INVESTIGATOR lat: 45.74848 lon: 4.84669 facility: Hôpital de la Timone, CHU de Marseille city: Marseille zip: 13385 country: France name: Marc GAINNIER role: CONTACT phone: 04 91 38 85 50 phoneExt: +33 email: marc.gainnier@ap-hm.fr name: Marc GAINNIER role: PRINCIPAL_INVESTIGATOR lat: 43.29551 lon: 5.38958 facility: Hôpital lapeyronie, CHU de Montpellier city: Montpellier zip: 34295 country: France name: Kada KLOUCHE role: CONTACT phone: 04 67 33 77 36 phoneExt: +33 email: k-klouche@chu-montpellier.fr name: Kada KLOUCHE role: PRINCIPAL_INVESTIGATOR lat: 43.61092 lon: 3.87723 facility: Hôpital Universitaire Carémeau city: Nîmes zip: 30029 country: France name: Claire ROGER role: CONTACT phone: 04 66 68 33 31 phoneExt: +33 email: claire.roger@chu-nimes.fr name: Claire ROGER role: PRINCIPAL_INVESTIGATOR lat: 43.83333 lon: 4.35 facility: Hôpital Lyon-Sud city: Pierre-Bénite zip: 69310 country: France name: Auguste DARGENT role: CONTACT phone: 04 78 86 21 18 phoneExt: +33 email: auguste.dargent@chu-lyon.fr name: Auguste DARGENT role: PRINCIPAL_INVESTIGATOR lat: 45.7009 lon: 4.82511 facility: Hôpital Nord, CHU de St Etienne city: Saint-Priest-en-Jarez zip: 42270 country: France name: Guillaume THIERY role: CONTACT phone: 04 77 12 78 62 phoneExt: +33 email: guillaume.thiery@chu-st-etienne.fr name: Guillaume THIERY role: PRINCIPAL_INVESTIGATOR lat: 45.47501 lon: 4.37614 facility: Hôpital Nord-Ouest city: Villefranche-sur-Saône zip: 69655 country: France name: Julien ILLINGER role: CONTACT phone: 04 74 09 29 31 phoneExt: +33 email: jillinger@hno.fr name: Julien ILLINGER role: PRINCIPAL_INVESTIGATOR lat: 45.98333 lon: 4.71667 hasResults: False