hackint0sh/New-Dataset huggingface dataset:
The care pathway of patients with this type of disease represents an optimal setting for the implementation of an innovative narrative medicine pathway that, aided by integrative therapies, aims to support and accompain them in their treatment journey with a continuum of care. Moreover, the narrative medicine platform will implement the actual "static" way to define QoL with the classic Patient-Reported Outcomes (PROs) questionnaires, that reflect the patient status at a certain time point and not as a dinamic entity. It is on the basis of these assumptions that the present application project on the use of the DNMLAB digital narrative diary in the oncology department of the Fondazione Policlinico Gemelli was born. conditions: Breast Cancer conditions: Narrative Medicine conditions: HER2-negative Breast Cancer conditions: Patient Satisfaction studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: RETROSPECTIVE count: 50 type: ESTIMATED name: introduction of digital listening may improve the quality of life of patients withe breast cancer measure: Standardized quality-of-life measurement measure: Perceived quality of life measure: Personalization of the care pathway measure: Quality of the patient-physician relationship. measure: Interaction between multidisciplinary teams measure: Patient involvement and compliance in the care pathway measure: lifestyles best suited to positively affect quality of life measure: Awareness of disease condition sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06348641 id: 2011-KAEK-25 2022/12-11 briefTitle: Reducing Pain and Increasing Comfort During a Retinopathy of Prematurity Examination overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2025-04-20 date: 2025-04-20 date: 2024-04-05 date: 2024-04-05 name: Nurgül Tekin class: OTHER briefSummary: The aim of this study is to investigate the effect of baby massage applied to babies with retinopathy of prematurity on the pain and comfort of the newborn.
This was randomised-controlled study in the NICU at the Health Sciences University Bursa High Specialization Training and Research Hospital, Bursa, Turkey. The population of the study will consist of preterms hospitalized in the neonatal intensive care unit during the time period of the study. In the calculation of the sample size, the power level was 80% and the significance level was 5%. When the effect size was determined as 0.8 in the examination of the difference between the experimental and control groups in terms of the premature infant pain profile (PIPP) variable, it was determined by the statistical expert that the number of babies to be included in each group was 26 and 52 babies in total should be included in the study. Based on this, the study sample was determined as 60 preterm infants in 30 experimental and 30 control groups. Block randomization method will be applied in the randomization of the groups.
The researcher has an IAIM infant massage certificate. Before starting the infant massage, jewelry will be removed and hands will be washed. In the study, leg and face massage will be applied among the massage techniques in the IAIM guidelines. conditions: Pain conditions: Retinopathy of Prematurity conditions: Premature Baby 26 to 32 Weeks conditions: Premature Baby 33 to 36 Weeks studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: In the calculation of the sample size, the power level was 80% and the significance level was 5%. When the effect size was determined as 0.8 in the examination of the difference between the experimental and control groups in terms of the premature infant pain profile (PIPP) variable, it was determined by the statistical expert that the number of babies to be included in each group was 26 and 52 babies in total should be included in the study. Based on this, the study sample was determined as 60 preterm infants in 30 experimental and 30 control groups. Block randomization method will be applied in the randomization of the groups. primaryPurpose: SUPPORTIVE_CARE masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: baby massage measure: Pain during examination for retinopathy of prematurity measure: Comfort during retinopathy of prematurity examination sex: ALL minimumAge: 1 Day maximumAge: 40 Days stdAges: CHILD hasResults: False
nctId: NCT06348628 id: P/38/04/2021 briefTitle: Motivational Interviewing in the Management of Non Alcoholic Fatty Liver Disease overallStatus: ACTIVE_NOT_RECRUITING date: 2022-05-31 date: 2025-01 date: 2025-07 date: 2024-04-05 date: 2024-04-05 name: Madunil Anuk Niriella class: OTHER briefSummary: The goal of this study is to assess if motivational counselling works to reduce the weight in participants with Non Alcoholic Fatty Liver Disease (NAFLD). conditions: Non-Alcoholic Fatty Liver Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 231 type: ACTUAL name: Motivational Interview name: Placebo measure: Change in weight after 1 year compared to baseline measure: Change in Aspartate aminotransferase (AST) level and Alanine aminotransferase (ALT) level after 1 year compared to baseline measure: Change in platelet count after 1 year compared to baseline measure: Change in waist circumference and hip circumference after 1 year compared to baseline measure: Change in total fat percentage and visceral fat percentage after 1 year compared to baseline measure: Change in motivation for weight loss after 1 year compared to baseline measure: Change in depression, anxiety and stress after 1 year compared to baseline measure: Change in quality of life after 1 year compared to baseline sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Faculty of Medicine, University of Kelaniya city: Ragama state: Western Province zip: 11010 country: Sri Lanka lat: 7.0292 lon: 79.917 hasResults: False
nctId: NCT06348615 id: DEFBODY briefTitle: Study Aimed at Evaluation of the Effectiveness and Tolerability of an Anti-cellulite Cream Medical Device acronym: DEFBODY overallStatus: RECRUITING date: 2024-01-23 date: 2024-04-23 date: 2024-06-07 date: 2024-04-05 date: 2024-04-08 name: ICIM International S.r.l. a socio unico class: INDUSTRY briefSummary: Post-marketing clinical study conducted on a CE medical device, named Defense Body, cellulite treatment, edematous fibrosclerotic panniculopathy (2nd and 3rd stage pathology), reducing draining cream-gel, to verify its effectiveness and tolerability on a panel of 56 subjects females affected by 2nd and 3rd degree PEF. The effectiveness of the device is measured in terms of reduction in thigh circumference, improvement in the appearance of the skin with reduction of the orange peel appearance and improvement in skin smoothness. conditions: Cellulite studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 56 type: ESTIMATED name: Anti-cellulite cream-gel Medical Device (DEFBODY) measure: First day of study initiation: clinical history; personal and demographic data and previous or concomitant treatments measure: First day of study initiation: BMI measure: First day of study initiation: Measurement of waist circumference, hip circumference and thigh circumference measure: First day of study initiation: digital photographs of the area to be treated measure: First day of study initiation: skin profilemetry of the thigh measure: First day of study initiation: pinch test measure: After 28 days of treatment: recording of any concomitant pharmacological treatments that have occurred. measure: After 28 days of treatment: BMI measure: After 28 days of treatment: Measurement of waist circumference, hip circumference and thigh circumference measure: After 28 days of treatment: digital photographs of the area to be treated measure: After 28 days of treatment: skin profilemetry of the thigh measure: After 28 days of treatment: pinch test measure: After 28 days of treatment: AE or AED or Drop-off measure: After 28 days of treatment: satisfaction evaluation and compliance measure: After 56 days of treatment: recording of any concomitant pharmacological treatments that have occurred. measure: After 56 days of treatment: BMI measure: After 56 days of treatment: Measurement of waist circumference, hip circumference and thigh circumference measure: After 56 days of treatment: digital photographs of the area to be treated measure: After 56 days of treatment: skin profilemetry of the thigh measure: After 56 days of treatment: pinch test measure: After 56 days of treatment: AE or AED or Drop-off measure: After 56 days of treatment: evaluation of compliance measure: After 56 days of treatment: overall rating of product satisfaction sex: FEMALE minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: Dermatology Unit - I.R.C.C.S. Ospedale San Raffaele status: RECRUITING city: Milano country: Italy name: Santo Raffaele Mercuri role: CONTACT name: Vittoria Giulia Bianchi role: CONTACT lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06348589 id: 2023-05959-01 briefTitle: Orthostatic Hypotension and Blood Pressure Variability in Persons Undergoing Hemodialysis overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-09 date: 2024-09 date: 2024-04-04 date: 2024-04-04 name: Vrinnevi Hospital class: OTHER name: Linkoeping University briefSummary: High blood pressure is a risk factor for end-stage renal disease and is common in patients undergoing maintenance hemodialysis. Intradialytic hypotension is associated with an adverse prognosis. More knowledge is needed to identify patients at high risk for intradialytic hypotension and dialysis-associated hypotensive episodes. The aim of this observational single-center pilot study is to evaluate whether point-of-care ultrasound measurements may predict intradialytic hypotension and orthostatic blood pressure falls, in patients with chronic kidney disease who undergo maintenance hemodialysis. conditions: Chronic Kidney Disease Requiring Chronic Dialysis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 50 type: ESTIMATED measure: Intra-dialytic systolic blood pressure fall of 20 mmHg or larger measure: Post-dialytic orthostatic systolic blood pressure fall of 20 mmHg or larger sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06348576 id: AD-209P3 briefTitle: Phase III Study to Evaluate the Efficacy and Safety of AD-209 overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-02 date: 2025-02 date: 2024-04-04 date: 2024-04-04 name: Addpharma Inc. class: INDUSTRY briefSummary: The purpose of this study is to evaluate the efficacy and safety of AD-209 conditions: Hypertension,Essential studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 280 type: ESTIMATED name: AD-209 name: AD-2091 name: AD-209 Placebo name: AD-2091 Placebo measure: Change rate of MSSBP sex: ALL minimumAge: 19 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Korea University Guro Hospital city: Seoul country: Korea, Republic of name: Chang Gyu Park, M.D., Ph.D role: CONTACT name: Chang Gyu Park, M.D., Ph.D role: PRINCIPAL_INVESTIGATOR lat: 37.566 lon: 126.9784 hasResults: False
nctId: NCT06348563 id: 7437787981 briefTitle: AGED Diagnostics Liver Disease Assessment acronym: AGEDDX overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2025-05-15 date: 2025-09-15 date: 2024-04-04 date: 2024-04-04 name: Active Genomes Expressed Diagnostics, Corp class: INDUSTRY name: Arizona Clinical Trials name: Walter Reed National Military Medical Center briefSummary: Continue development of previously established methods to further validate candidate biomarkers that can discriminate steatosis from NASH and separately stage fibrosis from blood. The first assessment is to conduct test method verification to expand sample size to several hundred samples through whole genome sequencing methods. The second assessment is focused on biomarker validation by comparing targeted sequencing from patient plasma. Several sub- assessments will be conducted to support overall biomarker development efforts. conditions: NASH With Fibrosis conditions: NAFLD conditions: Healthy studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: SINGLE whoMasked: PARTICIPANT count: 400 type: ESTIMATED name: AGED Multiple Target Assay in Healthy Controls name: AGED Multiple Target Assay in NAFLD Participants name: AGED Multiple Target Assay in Fibrosis Participants measure: Test Method Verification, Whole genome bisulfite sequencing assessment for liver tissue and plasma measure: Biomarker Validation, Targeted Epigenetic Sequencing Assessment sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: AGED Diagnostics city: Bethesda state: Maryland zip: 20002 country: United States name: Rachel Zayas role: CONTACT phone: 617-777-7971 email: rachel@ageddiagnostics.com lat: 38.98067 lon: -77.10026 hasResults: False
nctId: NCT06348550 id: BFMKP 01 briefTitle: Effect of the Association of Berberine Fitosoma® and Monacolin K MonaKoPure® on Glyco-metabolic Parameters in Dysglycemic and Dyslipidemic Patients. overallStatus: RECRUITING date: 2023-11-30 date: 2024-07 date: 2024-09 date: 2024-04-04 date: 2024-04-04 name: University of Pavia class: OTHER name: Foundation IRCCS San Matteo Hospital briefSummary: The objective of this study is to evaluate the effectiveness of the association Berberina Fitosoma® and monacolin K MonaKoPure® (Berberol® K supplement) compared to placebo on glucidic and lipid parameters in subjects with fasting blood glucose (FPG) values between 100 and 125 mg/dl and with total cholesterol (TC) values ≥ 200 mg/dl. conditions: Dyslipidemias conditions: Dysglycemia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 120 type: ESTIMATED name: Berberol® K name: Placebo measure: Variation of LDL cholesterol measure: Variation of lipid profile measure: Change in glycemic status sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS Policlinico S. Matteo Foundation status: RECRUITING city: Pavia zip: 27100 country: Italy name: Giuseppe Derosa, MD, PhD role: CONTACT email: giuseppe.derosa@unipv.it name: Pamela Maffioli, MD role: CONTACT email: p.maffioli@smatteo.pv.it name: Giuseppe Derosa, MD, PhD role: PRINCIPAL_INVESTIGATOR name: Pamela Maffioli, MD role: SUB_INVESTIGATOR lat: 45.19205 lon: 9.15917 hasResults: False
nctId: NCT06348537 id: Polyphenol-Fibromyalgia briefTitle: Effects of Olive Polyphenols in Fibromyalgia Patients overallStatus: COMPLETED date: 2021-01-20 date: 2021-04-01 date: 2023-09-01 date: 2024-04-04 date: 2024-04-04 name: Universidad de Granada class: OTHER name: Solvitae Medical, S.L name: University of Jaén briefSummary: To study the effects of a nutritional intervention with an olive (poly)phenol preparation in female patients with FM. conditions: Fibromyalgia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 40 type: ACTUAL name: Olive Polyphenols name: Placebo measure: Plasma proteome measure: Lipid peroxidation measure: Aldolase measure: C-reactive protein (CRP) measure: Impact of fibromyalgia measure: Quality of Life measure: Red blood cells measure: Haemoglobin measure: Fibrinogen measure: Total cholesterol measure: Cholesterol ratio measure: LDL cholesterol measure: Cortisol sex: FEMALE minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Jaén city: Jaén zip: 23071 country: Spain lat: 37.76922 lon: -3.79028 hasResults: False
nctId: NCT06348524 id: ferumoxytol_2015 briefTitle: Ferumoxytol-enhanced Magnetic Resonance Imaging overallStatus: NOT_YET_RECRUITING date: 2024-08-03 date: 2024-12-30 date: 2025-12-30 date: 2024-04-04 date: 2024-04-04 name: Transmed Solutions class: OTHER briefSummary: There are no current alternatives to diagnostic contrast-requiring imaging for patients with an eGFR \<30mL/min due to the association of gadolinium-based imaging modalities to nephrogenic systemic fibrosis and iodinated contrast-induced kidney injury. Ferumoxytol-enhanced imaging may offer an alternative approach. conditions: Coronary Artery Disease studyType: INTERVENTIONAL phases: PHASE3 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 36 type: ESTIMATED name: Ferumoxytol injection measure: Detect the absence of ≥50% stenosis in the coronary artery tree measure: Detect stenosis in proximal and distal segments of the coronary artery tree measure: Compare ferumoxtyol enhanced magnetic resonance angiography with stress echocardiography sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06348511 id: 0165-22-TLV briefTitle: XTics - A Gamified Enhancer of Non-Pharmacological Interventions in Tic Disorders overallStatus: COMPLETED date: 2022-07-01 date: 2022-12-31 date: 2022-12-31 date: 2024-04-04 date: 2024-04-04 name: Tel-Aviv Sourasky Medical Center class: OTHER_GOV briefSummary: The investigators developed a neuroscientifically-informed gamified tic-therapy platform. The investigators previously identified tic-triggering elements in movies and video games. Next, the investigators employed these elements to generate and validate a gamified intervention protocol, which is based on a video game the investigators designed (called XTics). The study tests the efficacy of the gamified tool integrated in an exposure and response prevention (ERP) protocol to enhance both patient's compliance and clinical outcome. conditions: Tic Disorders studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: The study tested the impact of contingent and immediate reward (ICR) given by the game in respect to the participant's tic frequency relative to a random and non-contingent delayed reward (DR) provided by the end of the training day. Each participant underwent three training days in each of the the modes during one week. The training days included 3 (first day) or 4 (second and third days) game sessions. The order of the training modes was random. primaryPurpose: DIAGNOSTIC masking: SINGLE maskingDescription: Personnel who interact directly with the study subjects were not aware of the assigned treatments. Personnel who analyze the data collected from the study are not aware of the treatment applied to any given group. whoMasked: INVESTIGATOR count: 35 type: ACTUAL name: XTics measure: The Tic Yale Global Tic Severity Scale (YGTSS) measure: The Parent Tic Questionnaire (PTQ) measure: Premonitory Urge for Tic Scale (PUTS) measure: The Subjective Units of Distress Scale (SUDS) measure: The "Urge Thermometer" measure: Rush Videotape Protocol measure: Tic-to-tic interval measure: The Screen for Child Anxiety Related Emotional Disorders (SCARED) measure: The Children Depression Inventory (CDI) measure: The Conners' Parent Rating Scale-Revised Long Form (CRS:RL) measure: Obsessive Compulsive Inventory-Child Version (OCI-CV) measure: The Behavior Rating Inventory of Executive Function (BRIEF) measure: The Emotion Regulation Questionnaire (ERQ) measure: User Engagement Scale (UES) sex: ALL minimumAge: 7 Years maximumAge: 15 Years stdAges: CHILD facility: Sagol Brain Institute, Tel Aviv Sourasky Medical Center city: Tel Aviv country: Israel lat: 32.08088 lon: 34.78057 hasResults: False
nctId: NCT06348498 id: TSL-TCM-JSP-Ⅰb briefTitle: Pharmacokinetic and Pharmacodynamic of Jia Shen Tablets in Chronic Heart Failure overallStatus: NOT_YET_RECRUITING date: 2024-03-31 date: 2026-06-30 date: 2026-06-30 date: 2024-04-04 date: 2024-04-04 name: Tasly Pharmaceutical Group Co., Ltd class: INDUSTRY briefSummary: Evaluate the pharmacokinetic and pharmacodynamic characteristics of Jia Shen Tablets in patients with Chronic Heart Failure. conditions: Heart Failure studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 18 type: ESTIMATED name: Jia Shen Tablet measure: Pharmacokinetic characteristic evaluation：Maximum observed plasma concentration (Cmax) measure: Plasma PK analysis: Time to reach peak or maximum observed concentration following drug administration (Tmax) measure: Plasma PK analysis: Area under curve at steady state (AUCss) measure: NT-proBNP measure: 6-Minutes-Walking-Test (6MWT) measure: Echocardiogram results measure: NYHA classification measure: AEs sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine city: Tianjin state: Tianjin country: China name: Yuhong Huang role: CONTACT lat: 39.14222 lon: 117.17667 hasResults: False
nctId: NCT06348485 id: VGHTCCTC_NPCbleeding001 briefTitle: Massive Nasal Bleeding in Patients With NPC Received Curative RT overallStatus: COMPLETED date: 1994-12-01 date: 2019-04-30 date: 2024-02-29 date: 2024-04-04 date: 2024-04-04 name: Taichung Veterans General Hospital class: OTHER briefSummary: To investigate the incidence, predictive markers, and survival impact of massive nasal bleeding in nasopharyngeal carcinoma (NPC) patients who received curative radiotherapy (RT) with/without chemotherapy. A total of 1327 patients with previously untreated, biopsy-proven NPC, and no distant metastasis were retrospective reviewed. Investigators analyzed the occurrence rates of massive nasal bleeding between different characteristics and tried to identify important predictive factors. Investigators compared overall survival between patients with and without massive nasal bleeding by Kaplan-Meier method. conditions: Nasopharyngeal Carcinoma Patients Treated With Curative Radiotherapy studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: RETROSPECTIVE count: 1327 type: ACTUAL name: Patients without massive nasal bleeding name: Patients with massive nasal bleeding measure: Massive Nasal Bleeding Rate measure: Overall Survival sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Taichung Veterans General Hospital city: Taichung zip: 407 country: Taiwan lat: 24.1469 lon: 120.6839 hasResults: False