hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06335511 id: 631-2021-OSS-AUSLBO briefTitle: Decompression Versus Instrumented Fusion for Lumbar Degenerative Disease. Clinical and Biomechanical Outcome Study acronym: ARCHIMEDE overallStatus: RECRUITING date: 2022-10-10 date: 2025-02-28 date: 2025-02-28 date: 2024-03-28 date: 2024-03-28 name: Azienda Usl di Bologna class: OTHER_GOV briefSummary: Identification of clinical and instrumental parameters that could predict the outcome of surgical decompression of lumbar degenerative stenosis. conditions: Lumbar Spinal Stenosis conditions: Degenerative Lumbar Spinal Stenosis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED name: microsurgical decompression name: decompression and instrumented fusion measure: Short Form 12 measure: Short Form 12 measure: Short Form 12 measure: Short Form 12 measure: Visual Analogue Scale measure: Visual Analogue Scale measure: Visual Analogue Scale measure: Visual Analogue Scale measure: Oswestry Disability Index measure: Oswestry Disability Index measure: Oswestry Disability Index measure: Oswestry Disability Index measure: EuroQol-5D measure: EuroQol-5D measure: EuroQol-5D measure: EuroQol-5D measure: Postural Balance measure: Postural Balance measure: Postural Balance measure: Postural Balance measure: Locomotor performance measure: Locomotor performance measure: Locomotor performance measure: Locomotor performance measure: Spinal mobility measure: Spinal mobility measure: Spinal mobility measure: Spinal mobility measure: Evaluation of costs sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS Istituto Ortopedico Rizzolo status: RECRUITING city: Bologna zip: 40136 country: Italy name: Giovanni Barbanti Brodano, Dr. role: CONTACT phone: +390516366971 email: giovanni.barbantibrodano@ior.it lat: 44.49381 lon: 11.33875 facility: IRCCS Istituto delle Scienze Neurologiche di Bologna status: RECRUITING city: Bologna zip: 40139 country: Italy name: Alfredo Conti, Prof. role: CONTACT phone: 3382131017 email: alfredo.conti2@unibo.it lat: 44.49381 lon: 11.33875 hasResults: False
nctId: NCT06335498 id: 130-0008P briefTitle: Further Study of AFGen1 Clinical Performance acronym: CS3 overallStatus: ACTIVE_NOT_RECRUITING date: 2024-04-02 date: 2024-04-12 date: 2024-04-19 date: 2024-03-28 date: 2024-04-12 name: TriVirum, Inc. class: INDUSTRY briefSummary: AFGen1 is indicated for use on symptomatic or asymptomatic adults who are at risk of developing or who have atrial fibrillation, where a software assisted analysis of ambulatory ECG is needed to identify episodes of Afib. The purpose of this study is to establish further evidence for the clinical performance of AFGen1 on human participants. conditions: Atrial Fibrillation conditions: Afib conditions: ECG studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 20 type: ESTIMATED name: ECG co-measurement name: Periodic ECG triggered measurement measure: Bland-Altman Comparison measure: Qualitative Evaluation measure: Adhesive performance sex: ALL minimumAge: 18 Years maximumAge: 90 Years stdAges: ADULT stdAges: OLDER_ADULT facility: 1808 49Th St Ct NW city: Gig Harbor state: Washington zip: 98335 country: United States lat: 47.32926 lon: -122.58013 hasResults: False
nctId: NCT06335485 id: 2020- P123456 briefTitle: Cognitive Behavioral Therapy (CBT) Pain Prevention Intervention for Women Undergoing Surgery overallStatus: COMPLETED date: 2021-04-01 date: 2022-09-29 date: 2022-09-29 date: 2024-03-28 date: 2024-03-28 name: Brigham and Women's Hospital class: OTHER briefSummary: This study investigates a Cognitive Behavioral Therapy (CBT) intervention for women who are undergoing elective surgery. The objective is to provide a toolkit of stress management techniques to decrease pain and opioid use following surgery. conditions: Back Pain conditions: Cognitive Behavioral Therapy conditions: Surgery studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Patients are randomized to either the intervention group or general group, for the intervention group patients will be randomly assigned to attend 4 weekly online virtual CBT sessions that will provide information on stress and pain reduction techniques before surgery, and 2 sessions following patient surgery. primaryPurpose: PREVENTION masking: NONE count: 32 type: ACTUAL name: Cognitive Behavioral Therapy measure: Numeric Pain Rating measure: Pain Medication Usage measure: Activity Tracking (Digital Phenotyping) sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Brigham and Women's Hospital city: Boston state: Massachusetts zip: 02115 country: United States lat: 42.35843 lon: -71.05977 hasResults: False
nctId: NCT06335472 id: Three nerves radiofrequency briefTitle: Three Nerves Versus Suprascapular Nerve Radiofrequency Combined With Hydrodissection in Adhesive Capsulitis overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-02-03 date: 2027-03-05 date: 2024-03-28 date: 2024-03-28 name: Assiut University class: OTHER briefSummary: comparison between effect of three nerves pulsed radiofrequency combined with hydro-dissection versus suprascapular nerve Pulsed Radiofrequency combined with hydrodissection on pain control in adhesive capsulitis within six months follow up. conditions: Analgesia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Ultrasound-guided effect of three nerves pulsed radiofrequency versus supra-scapular nerve pulsed radiofrequency both combined with hydro-dissection in reducing the intensity of pain in adhesive capsulitis primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: pain control and range of motion in adhesive capsulitis whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 60 type: ESTIMATED name: 3 nerves pulsed radiofrequency with hydrodissection name: suprascapular nerve pulsed radiofrequency with hydrodissection measure: The most effective modality on pain management of shoulder adhesive capsulitis using visual analog score. sex: ALL minimumAge: 30 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Assiut university Hospital city: Assiut country: Egypt name: safaa noaman, assistant lecturer role: CONTACT lat: 27.18096 lon: 31.18368 hasResults: False
nctId: NCT06335459 id: Epidemiology of bunion briefTitle: Epidemiology of Bunion and Risk Factors overallStatus: NOT_YET_RECRUITING date: 2024-07-24 date: 2025-04-05 date: 2025-06-01 date: 2024-03-28 date: 2024-03-28 name: Assiut University class: OTHER briefSummary: Analysis of the collected data to determine:
* Risk factors. Radiological and clinical patterns and their association with specific risk factors Of Hallux Valgus conditions: Hallux Valgus and Bunion studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 2000 type: ESTIMATED name: epidemiology measure: History taken and well clinical examination and AP Foot standing position of 2000 randomly case with determination of Hallux Valgus angles knowing if It's Hallux Valgus or not calculating The prevalence sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06335446 id: 011040- AT validation phase id: PG/16/10/32016 type: OTHER_GRANT domain: British Heart Foundation briefTitle: Identification, Electro-mechanical Characterisation and Ablation of Driver Regions in Persistent Atrial Fibrillation overallStatus: COMPLETED date: 2016-10 date: 2019-10 date: 2019-10 date: 2024-03-28 date: 2024-03-28 name: Barts & The London NHS Trust class: OTHER briefSummary: Atrial fibrillation (AF) is the most common sustained heart rhythm abnormality. Its incidence is increasing partly due to the aging population and it has been referred to as a growing epidemic. AF results in irregular contractions of the heart causing unpleasant symptoms of palpitations and increasing the risk of stroke, heart failure and death. Percutaneous catheter ablation is a safe treatment option in symptomatic patients with AF. The success rate of these procedures have improved with time due to our better understanding of AF, development of new techniques and technology, and greater physician experience. However, the success rate of these procedures still only remains around 70%. This is secondary to our limited ability to find the areas that drive AF.
STAR mapping is a novel mapping system that has been developed with a view of better identifying the sites that drive AF through taking into account the mechanisms of AF we have so far demonstrated. To validate this mapping system we aim to use it in patients with atrial tachycardia (AT), which is a heart rhythm abnormality of which the mechanism can be readily identified with the existing mapping systems used in clinical practice. We will demonstrate that the STAR mapping algorithm can effectively map AT. conditions: Atrial Tachycardia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30 type: ACTUAL name: Novel mapping algorithm measure: STAR maps compared to conventional maps sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Barts Heart Centre city: London zip: EC1A 7BE country: United Kingdom lat: 51.50853 lon: -0.12574 hasResults: False
nctId: NCT06335433 id: RM_30_06_22b briefTitle: Isometric Handgrip Training Frequency and Blood Pressure in People With Hypertension overallStatus: RECRUITING date: 2024-03-20 date: 2026-03 date: 2026-03 date: 2024-03-28 date: 2024-03-28 name: Swansea University class: OTHER briefSummary: Hypertension is the most important cause of cardiovascular disease (CVD), stroke, and premature death (WHO, 2021). It is estimated by The World Health Organisation in 2021 that 1.4 billion individuals across the globe have high blood pressure, with only 14% of people actively managing these elevated levels. Simple and effective lifestyle strategies are required to help people improve their blood pressure and/or attenuate increases in blood pressure with ageing. Physical activity is one possible strategy: in previous research, several different types of physical activity have been shown to have beneficial effects on blood pressure (Blackwell et al., 2017). However, many individuals do not adhere to currently recommended levels of physical activity (150 mins of moderate intensity physical activity per week), due to a combination of the required time commitment, lack of motivation, and the associated levels of effort, exertion, and physical discomfort (Korkiakangas et al 2009). Thus, there is a need to identify alternative exercise interventions which will overcome these barriers but remain effective at improving blood pressure (Herrod, Lund, \& Phillips, 2021, Toohey et al, 2018).
Low intensity isometric hand grip exercise training (IET) has been shown to result in large decreases in resting blood pressure in younger and older age groups, in both men and women, and in individuals with normal as well as elevated baseline blood pressure (Badrov et al, 2013; Bentley et al., 2018; Millar et al., 2014). In this research, IET has almost universally involved performing 4 x 2 IET holds at 30% of maximal voluntary contraction, 3 times a week, over a 4-8-week intervention (Millar et al, 2014). There are very few studies that have investigated the effect of changing different protocol parameters on changes in blood pressure and vascular health, and the minimal effective dose of IET is unknown. Defining the minimal effective dose of different types of exercise may help overcome key barriers to exercise by lowering the required time commitment, reducing perceived effort/exertion, and promoting more positive affective responses. One important modifiable parameter is training frequency and it is unknown whether reducing the frequency of IET will reduce the efficacy for improving blood pressure.
Therefore, the primary objective of this study is to determine if reducing the frequency of isometric handgrip training from four times a week to two times a week will affect the improvements in resting blood pressure and vascular health in people with hypertension. A secondary objective is to investigate the acute affective and perceptual responses to sessions of IET and the effect of training on these acute affective/perceptual responses. conditions: Hypertension studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomised controlled trial primaryPurpose: TREATMENT masking: NONE count: 45 type: ESTIMATED name: Exercise Training (Isometric Handgrip Exercise) measure: Office measured supine and seated systolic, diastolic and mean arterial pressure measure: Office measured central systolic, diastolic and mean arterial pressure measure: 24-h mean ambulatory systolic, diastolic, and mean arterial pressure measure: Daytime ambulatory systolic, diastolic, and mean arterial pressure measure: Sleeping ambulatory systolic, diastolic and mean arterial pressure measure: Carotid-Femoral Pulse Wave Velocity measure: Affective Valence (Feeling Scale) measure: Ratings of perceived exertion sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Swansea University status: RECRUITING city: Swansea state: Wales zip: SA18EN country: United Kingdom name: Richard Metcalfe, PhD role: CONTACT phone: 01792205678 phoneExt: 4779 email: r.s.metcalfe@swansea.ac.uk lat: 51.62079 lon: -3.94323 hasResults: False
nctId: NCT06335420 id: 324-2023-GB briefTitle: Prophylactic Properties of Carrot Juice in Patients With High-Risk Colorectal Polyps acronym: Px7 overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-04 date: 2026-09 date: 2024-03-28 date: 2024-03-28 name: Odense University Hospital class: OTHER name: Karolinska Institutet name: Umeå University name: Uppsala University Hospital name: Sahlgrenska University Hospital, Sweden name: Svendborg Hospital briefSummary: The goal of this prospective randomized double-blinded bi-national study is to test the prophylactic effect of polyacetylenes from carrots on the population of patients who had a resection of high-risk adenomas of the large bowel.
Researchers will compare the group with ingestion of FaOH/FaDOH rich carrot juice versus the group consuming placebo juice, to see if the polyacetylenes significantly reduces neoplastic transformation and growth in high-risk patients. conditions: Colorectal Cancer Prevention studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 400 type: ESTIMATED name: Carrot juice from Yellowstone carrots cultivars name: Placebo juice measure: Number and size of polyps found at the one-year follow up colonoscopy measure: Polyp number and size in relation to carrot consumption measurement measure: Compliance rate (Juice consumption level) measure: Side effects measure: Acceptability of treatment sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Surgery, Odense University Hospital city: Odense zip: 5000 country: Denmark lat: 55.39594 lon: 10.38831 hasResults: False
nctId: NCT06335381 id: 24-0131 id: 1R01NR021134-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R01NR021134-01 briefTitle: MOMs Chat and Care Study acronym: MOMs-CC overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2027-12-31 date: 2028-06-30 date: 2024-03-28 date: 2024-04-01 name: Northwell Health class: OTHER name: National Institute of Nursing Research (NINR) briefSummary: The purpose of this pragmatic, randomized clinical trial designed to test the effectiveness of an integrated care model approach at two different levels of intensity designed to facilitate timely, appropriate care for high-risk Black birthing people and reduce risk for severe maternal morbidity (SMM). Eligible Black birthing people (n = 674) will be recruited and randomized to one of two study arms: MOMs High-Touch (MOMs-HT) vs. MOMs Low-Touch (MOMs-LT). The two study arms will be compared on incidence of SMM at labor and delivery (Aim 1), incidence rate of SMM-related hospitalizations at 1-month and 1-year postpartum (Aim 1a), time to preeclampsia diagnosis and initiation of treatment (Aim 2), change in perceived social support domains (Aim 3), and physical activity trajectories (exploratory Aim 4). Mixed methods will also be used to examine facilitators and barriers to implementation (Aim 5). Findings from this study will help to determine how to feasibly implement an effective and sustainable integrated care approach to address SMM disparities. conditions: Severe Maternal Morbidity studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Participants will be assigned to one of two groups in parallel for the duration of the study. primaryPurpose: PREVENTION masking: SINGLE maskingDescription: The Principal Investigator and Biostatistician will be masked. whoMasked: INVESTIGATOR count: 674 type: ESTIMATED name: Northwell Pregnancy & Peds Chats name: Prenatal Telehealth Visits name: Postpartum Telehealth Visits name: Home Blood Pressure Monitor name: Fitbit measure: Severe maternal morbidity (SMM) measure: Preeclampsia measure: Informational Support measure: Emotional Support measure: Tangible Support measure: Minutes of Physical Activity measure: Barriers to Exercise sex: FEMALE minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Northwell Health city: Manhasset state: New York zip: 11030 country: United States name: Stephanie L Fitzpatrick, PhD role: CONTACT lat: 40.79788 lon: -73.69957 hasResults: False
nctId: NCT06335368 id: 201512178RINC briefTitle: Assessment of Nutritional and Growth Status in Rett Syndrome Patients overallStatus: COMPLETED date: 2016-03-09 date: 2016-05-23 date: 2020-10-26 date: 2024-03-28 date: 2024-03-28 name: National Taiwan University Hospital class: OTHER briefSummary: Children with Rett syndrome are in a period of rapid growth, and proper and appropriate nutritional support is very important. Past foreign research papers it has been pointed out that most of these patients have feeding difficulties, dysphagia, and digestive tract abnormalities, are often constipated, and may suffer from osteoporosis and other problems. Lack of proper nutritional support will seriously affect their growth, development and health. in view of There is a lack of relevant research in China, so the investigators would like to use this research to explore the nutritional, growth and postural status of Rett's disease patients, as the reference direction and goal of dietary adjustment and nutritional support for patients, and establish dietary and nutritional strategies for sick children in Taiwan. conditions: Rett Syndrome conditions: Neurologic Disorder studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: RETROSPECTIVE count: 70 type: ACTUAL name: Nutrition and Growth Status measure: gender, age , disease history checklist measure: Change in Body height measure: Change in Body weight measure: Change in knee height measure: Change in arms height measure: Change in waist measure: Change in hip circumferences sex: ALL minimumAge: 1 Year maximumAge: 18 Years stdAges: CHILD stdAges: ADULT hasResults: False
nctId: NCT06335355 id: SHR-1316-307 briefTitle: A Phase II/III Study of Adebrelimab in Combination With SHR-8068 and Chemotherapy in Advanced or Metastatic NSCLC Patients overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2028-10 date: 2030-10 date: 2024-03-28 date: 2024-03-28 name: Shanghai Shengdi Pharmaceutical Co., Ltd class: INDUSTRY briefSummary: Evaluating the Efficacy and safety of Adebrelimab in Combination with Platinum-based Doublet Chemotherapy and SHR-8068 as First-line Therapy for Patients with Advanced or Metastatic NSCLC Carrying STK11/KEAP1/KRAS Mutations conditions: Non-squamous Non-small Cell Lung Cancer studyType: INTERVENTIONAL phases: PHASE2 phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 401 type: ESTIMATED name: Adebrelimab + SHR-8068 + Pemetrexed + Carboplatin name: Camrelizumab + Pemetrexed + Carboplatin name: Adebrelimab + Pemetrexed + Carboplatin measure: Investigator-assessed Objective Response Rate (Phase One) measure: Overall Survival (Phase Two) measure: The incidence and severity of Adverse Events (AEs) (Phases One and Two) measure: Duration of Response (DoR) based on Investigator Assessment (Phases One and Two) measure: Disease Control Rate (DCR) based on Investigator Assessment (Phases One and Two) measure: Progression-Free Survival (PFS) based on Investigator Assessment (Phases One and Two) measure: Overall Survival (OS) (Phase One) measure: Objective Response Rate (ORR) based on Investigator Assessment (Phase Two) sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Affiliated Tumor Hospital of Shandong First Medical University city: Jinan state: Shandong zip: 250117 country: China name: Jinming Yu role: PRINCIPAL_INVESTIGATOR lat: 36.66833 lon: 116.99722 hasResults: False
nctId: NCT06335342 id: IEO 0726 briefTitle: Radiotherapy Treatments for Neoplasms in the Head and Neck Region overallStatus: RECRUITING date: 2018-02-22 date: 2024-12-31 date: 2024-12-31 date: 2024-03-28 date: 2024-03-28 name: European Institute of Oncology class: OTHER briefSummary: The aim of this study is the evaluation of clinical and dosimetric aspects, tolerance, and effectiveness of radiotherapy treatments in the head and neck region.
Eligible patients undergoing radiotherapy for primary or secondary neoplasms localized in the head and neck anatomical region. conditions: Head and Neck Neoplasms studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 4050 type: ESTIMATED measure: Overall Survival measure: Disease free survival sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: European Institute of Oncology status: RECRUITING city: Milan country: Italy name: Barbara Alicja Jereczek role: CONTACT lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06335329 id: Pro00133616 briefTitle: Point-of-Care Ultrasound (POCUS) Findings and Impact on Vaping overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-07 date: 2025-07 date: 2024-03-28 date: 2024-04-02 name: Medical University of South Carolina class: OTHER briefSummary: Vaping has emerged as a prominent public health crisis in recent years. In 2023, the National Youth Tobacco Survey found that more than 2.1 million adolescents endorse vaping, with 25% of those endorsing daily use. Many adolescents also perceive vapes as safer than cigarettes, and more acceptable to use both indoors and outdoors compared to cigarettes. Vapes are available in numerous device and delivery systems, with the psychoactive agent commonly including nicotine or cannabis, although these can be of a wide variety of concentrations and formulations. They may be ultra-compact and allow for ease of concealment. In addition, they are produced in a variety of appealing flavorings such as candy, desserts, and fruits. Other constituents include the liquids and aerosolized components of the vaping cartridges, including formaldehyde, acetone, glycerol, propylene glycol, acetaldehyde, and heavy metals. Many of the flavoring concentrates, as well as the vaporized solvents, have not been evaluated for long term safety. One of these additives, vitamin E acetate, present in primarily illicit vaping devices, rose to national attention in 2019 for a suspected link to the dramatic increase in vaping/e-cigarette associated lung injury (EVALI) cases, with over 60 confirmed deaths since that time.