hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06316024 id: IRB2023056 briefTitle: Early Oral Intake of Different Types of Diets Affecting Gastrointestinal Function overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-03 date: 2025-03 date: 2024-03-18 date: 2024-03-18 name: Chiayi Christian Hospital class: OTHER briefSummary: The percentage of cesarean deliveries is on the rise, accounting for 30-40% of all deliveries in Taiwan. Following a cesarean delivery, a few doctors in Taiwan still adheres to the progressive eating regimen of "nothing per mouth" for 24 hours or until the patient passes flatus or hears bowel sounds. However, a meta-analysis has shown that early oral intake (6-8 hours) significantly reduces the time required for the restoration of gastrointestinal function and hospital stay compared to delayed oral intake. Furthermore, early oral intake has not shown to increase the likelihood of gastrointestinal complications. While several food types have been adopted for early oral intake, no study has investigated the effect of different food types on clinical outcomes regarding gastrointestinal function and hospital stay for cesarean delivery. Therefore, the objective of this study is to investigate the effect of different food types on clinical outcomes for cesarean delivery through a randomized controlled trial. The subjects of this study are pregnant women who come to Chiayi Christian Hospital to schedule cesarean deliveries. They are randomly assigned to one of four groups: nothing by mouth, water, juice/sports drink, or chewing gum. The relevant clinical outcomes, such as time to first bowel sound or readiness for discharge, are recorded. One-way analysis of variance or Chi-square test is used to compare the differences among the four groups. Our expected results could provide valuable information on the type of food that could be used to improve the recovery of mothers after cesarean delivery and increase the quality of breastfeeding. conditions: Cesarean Section studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 200 type: ESTIMATED name: water name: juice/sport drink group name: Chewing gum group measure: first time to bowel sound measure: beginning of breastmilk lactation measure: length of hospital stay measure: time to first drink measure: time to first solid food intake measure: duration of IV hydration measure: IV cannulae removal measure: first ambulation measure: first stool measure: satisfaction VAS (0-100) regarding the early intake sex: FEMALE minimumAge: 20 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06316011 id: MCG-chestpain briefTitle: MCG for Risk Stratifications of Patients With Chest Pain overallStatus: NOT_YET_RECRUITING date: 2024-03-20 date: 2024-04-30 date: 2024-08-31 date: 2024-03-18 date: 2024-03-18 name: Qilu Hospital of Shandong University class: OTHER briefSummary: This prospective cohort study is aimed at identification and risk stratification of patients who have symptoms of acute chest pain suspected with acute coronary syndrome （ACS） using Magnetocardiography （MCG）. conditions: Acute Coronary Syndrome studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 3620 type: ESTIMATED name: Magnetocardiography measure: Efficacy of MCG for the detection and risk stratification in patients with chest pain sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06315998 id: MCG-Structural briefTitle: Diagnosis of Structural Heart Disease Using MCG overallStatus: NOT_YET_RECRUITING date: 2024-03-18 date: 2025-04-30 date: 2025-09-30 date: 2024-03-18 date: 2024-03-18 name: Qilu Hospital of Shandong University class: OTHER briefSummary: The purpose of this prospective cohort study is to determine the parameters of cardiac magnetic imaging to identify structural heart disease using use transthoracic echocardiography or cardiac magnetic resonance as reference standard. conditions: Structural Heart Abnormality studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 2914 type: ESTIMATED name: Magnetocardiography measure: The efficacy of the MCG in identifying structural heart disease sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06315985 id: GAksoy briefTitle: Classical Turkish Music for Pregnant Women With Preeclampsia overallStatus: NOT_YET_RECRUITING date: 2024-03-20 date: 2024-09-20 date: 2025-03-20 date: 2024-03-18 date: 2024-03-20 name: Tarsus University class: OTHER briefSummary: Stress and Sleep of Classical Turkish Music in Pregnant Women Diagnosed with Preeclampsia in Clinics The study to be carried out to determine the effect on quality is a randomized controlled experimental research. All patients who comply with the limitations of the study and volunteer will be included in the study. When the studies in the literature are examined, there are a limited number of studies on the effects of music on pregnant women diagnosed with preeclampsia, and no studies have been found on the effects of music on stress and sleep quality in pregnant women with preeclampsia. This research aimed to determine the effect of Classical Turkish Music on stress and sleep quality in pregnant women diagnosed with Preeclampsia in clinics. conditions: Pre-Eclampsia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: This was a parallel group, randomized controlled trial conducted in a tertiary hospital in Mersin city center, Turkey. In parallel with the purpose of the study, participants were selected from the pregnant women diagnosed with preeclampsia who were hospitalized at Mersin City Training and Research Hospital.The population of the research is the G\* Power 3.1.9.4 was determined by analysis using. In the analysis, the sample size was taken as a sample size of at least 80%, a medium effect size (0.5) and a two-way type 1 error value of 0.05, since no study similar to the study could be found, and a total of 128 pregnant women were included in the two groups (in each group) to determine the difference between the averages of two independent groups. It was calculated as 64 pregnant women). Considering the drop out rate of 10% during the research, the total number of samples was found to be 142 (experimental group: n=71, control group: n=71) pregnant women. primaryPurpose: SUPPORTIVE_CARE masking: SINGLE maskingDescription: Participant will be masking. whoMasked: PARTICIPANT count: 142 type: ESTIMATED name: Experimental group: Listenning to the Turkish Classical Music to pregnant women diagnosed with preeclampsia measure: Perceived Stress measure: Sleep Quality sex: FEMALE minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Gülay Aksoy city: Mersin zip: 33080 country: Turkey name: Gülay Aksoy role: CONTACT phone: +905518627438 email: 220931003@tarsus.edu.tr name: Eylem Toker role: CONTACT email: eylemtoker@tarsus.edu.tr lat: 36.79526 lon: 34.61792 hasResults: False
nctId: NCT06315972 id: 2022-000054-28 briefTitle: Combining Clemastine and Aerobic Exercise to Treat Cognitive Dysfunction in Schizophrenia by Targeting Myelin Plasticity acronym: OligoTreat overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-11 date: 2028-04 date: 2024-03-18 date: 2024-03-20 name: LMU Klinikum class: OTHER briefSummary: Schizophrenia (SZ) is a broad clinical entity characterized by different subjective symptoms,behavioural signs, and disease course. Research has pointed to numerous biological indicators tentatively associated with neurocognitive dysfunction, brain structural and neurochemical alterations. Cognitive deficits occur as early as the prodromal phase of the illness and significantly determine its outcome. Pathophysiologically, SZ is regarded as a disconnectome disorder in which frontal and temporal brain regions are functionally disconnected, which contributes substantially to the development of cognitive dysfunction.
Impaired connectivity is related to synaptic (microconnectivity) and myelin (macroconnectivity) plasticity. With design-based stereology, a decreased number of oligodendrocytes (OLs) in the CA4 hippocampal subregion as the basis for disturbed myelination and impaired cognition, but also a decrease in the prefrontal cortex were observed. Animal studies demonstrated that clemastine enhances remyelination by increasing the differentiation of oligodendrocyte precursor cells (OPCs) and showed that aerobic exercise increases the rate of remyelination and proliferation of OPCs; this clinically meaningful effect of aerobic exercise is stronger in combination with clemastine. Furthermore, aerobic exercise improves everyday functioning, measured by the Global Assessment of Functioning (GAF) scale, and cognitive dysfunction in SZ and increases hippocampal volume, especially the volume in the hippocampal CA4 subregion. This regional volume change correlates negatively with global and cell-specific polygenic risk scores (PRSs), indicating that OPCs are involved in the genetic risk mechanisms and disturbed plasticity underlying SZ. In patients with multiple sclerosis, 90 days' administration of clemastine fumarate 10.72 mg/day, corresponding to clemastine 8 mg/day, significantly decreased the P100 latency delay of visual evoked potentials (VEPs) as a sign of myelin repair. In a bicentric, randomized, double-blind, controlled phase IIb clinical trial with a 2-arm parallel group design in patients with SZ, the study will compare the effects of aerobic exercise training plus clemastine vs. aerobic exercise training plus placebo over a period of 3 months on 1) everyday functioning and 2) working memory as primary outcomes. conditions: Schizophrenia studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 90 type: ESTIMATED name: clemastine (8 mg/day) name: Placebo measure: change in Global Assessment of Functioning measure: change in working memory performance sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06315959 id: ESPCHRONIC2023 briefTitle: Bilateral Erector Spinae Plane Block for Postoperative Chronic Pain After Open Heart Surgery overallStatus: RECRUITING date: 2024-04-01 date: 2025-01-15 date: 2025-03-15 date: 2024-03-18 date: 2024-04-02 name: Ondokuz Mayıs University class: OTHER briefSummary: The aim of this study is to investigate the effect of bilateral erector spinae plane (ESP) block application on postoperative chronic pain in patients undergoing on-pump open-heart surgery. At 3 months post-discharge, patients will be contacted by phone to assess their chronic pain status. Pain intensity and status will be evaluated using the Brief Pain Inventory, and the character of pain will be assessed using the Douleur Neuropathique 4 (DN4) score. Additionally, the patient's anxiety and depression status will be evaluated using the Hospital Anxiety and Depression Scale. conditions: Chronic Pain conditions: Cardiac Surgery conditions: Post Operative Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A block randomization list will be created by a doctor who does not participate in patient follow-up using a web-based program, 'Research Randomizer (Urbaniak and Plous, 2013)'. primaryPurpose: TREATMENT masking: QUADRUPLE maskingDescription: Sealed opaque envelopes containing study participation numbers will be used to assign each patient. A researcher not involved in patient follow-up will use the web-based "Research Randomizer" (Urbaniak and Plous 2013) tool to give each participation number to a random group with a 1:1 ratio. A nurse not an active investigator in the study will have each participant choose an envelope containing the study participation number. They will inform the anesthetist administering the block/blocks about which group the patient is in immediately before administration. Researchers, surgeons, and nurses will not be aware of the randomization of groups. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 50 type: ESTIMATED name: Bilateral ultrasound guided erector spinae plane block name: morphine PCA name: Control group name: morphine PCA measure: Chronic pain status measure: Postoperative opioid consumption in the first 24 Hours measure: Postoperative pain scores measure: The incidences of post-operative nausea and vomiting (PONV) measure: The number of patient requiring rescue analgesic measure: Time to extubation measure: The number of patients with complications measure: Chronic pain status at 6 months. measure: Length of stay in the ICU sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ondokuz Mayis University status: RECRUITING city: Samsun state: Atakum zip: 55139 country: Turkey name: BURHAN DOST role: CONTACT phone: 05327042493 email: burhandost@hotmail.com lat: 41.27976 lon: 36.3361 hasResults: False
nctId: NCT06315946 id: 17E3241 briefTitle: Efficacy of a Cryogenic Medical Device on Skin Tags Versus a Comparator Product. overallStatus: COMPLETED date: 2018-10-04 date: 2019-01-07 date: 2019-03-11 date: 2024-03-18 date: 2024-03-18 name: Oystershell NV class: INDUSTRY briefSummary: Evaluate the efficacy of the test medical device (Pixie® skin tag) in the treatment of skin tags versus a comparator product (Wortie® skin tag remover). conditions: Skin Tags studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: INVESTIGATOR count: 56 type: ACTUAL name: Pixie® skin tag name: Wortie® Skin Tag Remover measure: Percentage of subjects with successful treatment measure: Number of treatments measure: Visual aspect measure: Macrophotographs on skin tag remission measure: Evaluation of the skin condition measure: Degree of pain measure: Recording of adverse events sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: DERMSCAN - PharmScan city: Villeurbanne zip: 69100 country: France lat: 45.76667 lon: 4.88333 hasResults: False
nctId: NCT06315933 id: S-K1093 briefTitle: Anesthesia Neurodevelopmental Impact in Congenital Scoliosis Children overallStatus: RECRUITING date: 2020-01-13 date: 2025-12 date: 2026-12 date: 2024-03-18 date: 2024-03-18 name: Peking Union Medical College Hospital class: OTHER briefSummary: In the past, a large number of animal studies have suggested that anesthesia exposure has potential neurotoxic effects, resulting in persistent cognitive and behavioral deficits. At present, there is still a lack of sufficient clinical research evidence to prove whether anesthesia exposure has long-term effects on neurodevelopment. The existing clinical research data suggests that a single short-time anesthesia exposure in young children does not affect long-term neurodevelopmental outcomes. Early onset scoliosis, including congenital scoliosis, is a type of scoliosis deformity that occurs before the age of 10. Posterior scoliosis correction surgery is one of the common treatment. There is currently no research indicating the impact of early single or multiple long-duration anesthesia exposure on the neurological development of children with congenital scoliosis. The aim of this study is to determine the long-term effect of general anesthesia exposure on neurocognitive function and behavior in children with congenital scoliosis, in order to provide reference for related clinical work. conditions: General Anesthetics Toxicity studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: OTHER count: 80 type: ESTIMATED name: General anesthesia measure: full-scale intelligence quotient, FSIQ measure: Verbal Comprehension Index (VCI), Perceptual Reasoning/Organization Index (PRI/POI), Working Memory Index (WMI), Processing Speed Index (PSI) measure: CBCL Total score, CBCL Internalizing score, CBCL Externalizing score measure: SDQ Emotional symptoms, SDQ conduct problems, SDQ hyperactivity, SDQ peer problems, SDQ total difficulties, SDQ prosocial behaviors, SDQ impact factor sex: ALL minimumAge: 6 Years maximumAge: 16 Years stdAges: CHILD facility: Peking Union Medical College Hospital status: RECRUITING city: Beijing state: Beijing zip: 100730 country: China name: Lulu Ma, Dr. role: CONTACT phone: 0086-010-13811049619 email: malulu@pumch.cn lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06315920 id: AFMS-MREC 009/2021 briefTitle: Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department acronym: PASC overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-05-01 date: 2026-07-01 date: 2024-03-18 date: 2024-03-18 name: Oman Medical Speciality Board class: OTHER_GOV name: Armed Forces Hospital, Oman briefSummary: Introduction: This study focuses on the treatment of painful crises in Sickle Cell Disease (SCD) patients using Paracoxib, a non-opioid, compared to Morphine. It addresses the need for alternative medications that reduce opioid dependency while providing effective analgesia.
Assessment and Data Collection: The assessment of pain relief, side effects, and other relevant clinical outcomes is conducted by healthcare providers who are blinded to the treatment allocation. This minimizes bias in the evaluation of the treatment's efficacy and safety. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 226 type: ESTIMATED name: Parecoxib name: Morphine measure: Pain reduction at 60 mins. measure: Adverse Events/Side Effects measure: The need of rescue pain medications measure: Recurrent visit sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06315907 id: PBRC 2024-012 briefTitle: Development and Validation of a Brief Food Noise Questionnaire overallStatus: ENROLLING_BY_INVITATION date: 2024-04-25 date: 2024-05-24 date: 2024-05-28 date: 2024-03-18 date: 2024-04-26 name: Pennington Biomedical Research Center class: OTHER name: Weight Watchers International briefSummary: The purpose of the research is to develop and test the reliability and validity of a brief questionnaire to measure food noise. conditions: Eating Behavior studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 400 type: ESTIMATED name: Responses to survey questions measure: Scores on the food noise questionnaire sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Pennington Biomedical Research Center city: Baton Rouge state: Louisiana zip: 70806 country: United States lat: 30.45075 lon: -91.15455 hasResults: False
nctId: NCT06315894 id: PI-22-191 briefTitle: Supervised Computerized Active Program for People With Post-COVID Syndrome (SuperCAP Study) acronym: SuperCAP overallStatus: RECRUITING date: 2023-10-03 date: 2024-10 date: 2025-09 date: 2024-03-18 date: 2024-03-18 name: Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia class: OTHER name: Institut de Recerca de la SIDA IrsiCaixa name: Germans Trias i Pujol Hospital briefSummary: SuperCAP study is a project aimed at designing and implementing an online program for improvement of cognitive, emotional, and functional status in post-COVID condition. conditions: Post-COVID Condition studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized Controlled Trial primaryPurpose: TREATMENT masking: NONE count: 60 type: ESTIMATED name: SuperCAP Program measure: Change in Self-reported Cognitive Functioning measure: Change in Performance-based Cognitive Functioning measure: Change in Depression Symptoms measure: Change in Anxiety Symptoms measure: Change in Daily Activities Functioning measure: Change in Physical Activity measure: Change in Quality of Life sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Germans Trias I Pujol Hospital status: RECRUITING city: Badalona state: Barcelona zip: 08916 country: Spain name: Jose A MUñoz-Moreno, MD,PhD role: CONTACT phone: 93 465 7897 email: jmuñoz@lluita.org name: Jose A. Muñoz-Moreno, MD,PhD role: PRINCIPAL_INVESTIGATOR lat: 41.45004 lon: 2.24741 hasResults: False
nctId: NCT06315881 id: OSU-23116 id: NCI-2024-00666 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: U54CA287392 type: NIH link: https://reporter.nih.gov/quickSearch/U54CA287392 briefTitle: Informing Oral Nicotine Pouch Regulations to Promote Public Health overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2025-12-31 date: 2025-12-31 date: 2024-03-18 date: 2024-03-18 name: Ohio State University Comprehensive Cancer Center class: OTHER name: National Cancer Institute (NCI) briefSummary: This clinical trial evaluates the characteristics of oral nicotine pouches (ONPs) to determine if they are a comparable substitute to cigarette or smokeless tobacco (ST) products. ONPs contain nicotine but no tobacco and are used primarily by adult tobacco uses in the United States (US). ONPs are recognized by the Food and Drug Administration as having lower risk than combustible cigarettes and are approved as a modified risk tobacco product. While ONPs have lower toxic risk than other tobacco products, acute and longer term harm related to their use has not been studied. Information gathered from this study may identify product characteristics of ONPs that improve successful switching from high-risk cigarettes or ST to lower risk ONPs. conditions: Tobacco-Related Carcinoma studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 160 type: ESTIMATED name: Biospecimen Collection name: Cigarette name: Nicotine Oral Pouch name: Nicotine Oral Pouch name: Nicotine Oral Pouch name: Nicotine Oral Pouch name: Smokeless Tobacco name: Survey Administration name: Text Message-Based Navigation Intervention measure: Increased nicotine delivery measure: Liking measure: Craving/withdrawal suppression measure: Rate of switching to ONP measure: Rate of switching to ONPs sex: ALL minimumAge: 21 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ohio State University Comprehensive Cancer Center city: Columbus state: Ohio zip: 43210 country: United States name: Brittney L. Keller-Hamilton, PhD, MPH role: CONTACT phone: 614-366-9652 name: Brittney L. Keller-Hamilton, PhD, MPH role: PRINCIPAL_INVESTIGATOR lat: 39.96118 lon: -82.99879 hasResults: False
nctId: NCT06315868 id: 5590 briefTitle: Breast Cancer Subtype Characterization Through Patient's Derived Organoids. acronym: BCinsightPDO overallStatus: RECRUITING date: 2023-06-15 date: 2026-06-15 date: 2027-06-15 date: 2024-03-18 date: 2024-03-18 name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS class: OTHER briefSummary: Development of tools to predict patients chemo-sensitivity and identification of corresponding biomarkers is an urgent challenge for BC patients lacking targeted therapies, such as TNBC, or for patients experiencing relapse after adjuvant chemotherapy or targeted therapies.