hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06357624 id: Physiotherapy briefTitle: Effectiveness of Mulligan Mobilization Technique overallStatus: COMPLETED date: 2023-01-01 date: 2023-05-30 date: 2023-05-30 date: 2024-04-10 date: 2024-04-10 name: Karabuk University class: OTHER briefSummary: The aim of this study was to investigate the effects of the Mulligan mobilization technique (MMT) on pain intensity, joint position sense (JPS), kinesiophobia, and disability level in individuals with nonspecific neck pain. A total of 34 female individuals with nonspecific neck pain were included in the study. Pain intensity, JPS, kinesiophobia, and disability levels of all participants were evaluated before and after the 3-week intervention. Participants were randomly divided into two groups. In the first group, the participants received MMT by the physiotherapist twice a week for 3 weeks, and self-mobilization techniques as a home exercise program. The second group was trained only self-mobilization techniques. conditions: Neck Pain conditions: Disability Physical conditions: Kinesiophobia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 34 type: ACTUAL name: Mulligan mobilization name: Self-Mobilization measure: Disability measure: Neck Pain Severity measure: Joint Position Sense sex: FEMALE minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Tarik Ozmen city: Karabük country: Turkey lat: 41.20488 lon: 32.62768 hasResults: False
nctId: NCT06357611 id: OST1_015 briefTitle: Combination of Two Osteopathic Techniques for the Hamstring's Stretching Capacity in Basketball Female Players overallStatus: RECRUITING date: 2024-09-16 date: 2024-12-01 date: 2024-12-17 date: 2024-04-10 date: 2024-04-10 name: Natália Maria Oliveira Campelo class: OTHER briefSummary: It is known that there are studies that prove the effectiveness of muscle energy techniques and the fourth ventricle technique separately, however, information is scarce regarding the combination of the two and their effectiveness in the population. The aim of this randomized controlled study is to compare the immediate effects of the techniques compared to the muscle energy technique alone in female basketball players. conditions: Healthy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: In order to allocate each participant to an intervention group, each voluntary participation questionnaire was assigned a number. Subsequently, all the numbers of the participants in the sample were randomly distributed among the 3 groups by the principal investigator. primaryPurpose: OTHER masking: SINGLE whoMasked: PARTICIPANT count: 30 type: ESTIMATED name: Simulated technique name: Muscle energy technique name: 4th ventricle technique and muscular energy technique measure: Altered range of motion of the hamstring muscles. sex: FEMALE minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT facility: Escola Superior de Saúde do Porto status: RECRUITING city: Porto zip: 4200-072 country: Portugal name: Natália Campelo role: CONTACT phone: +35122 206 1000 email: nmc@ess.ipp.pt name: Natália MO Campelo role: PRINCIPAL_INVESTIGATOR lat: 41.14961 lon: -8.61099 hasResults: False
nctId: NCT06357598 id: QYFYEC2023-95 briefTitle: Preoperative Neoadjuvant Immunotherapy Combined With Chemotherapy for Stage Ⅲ Unresectable Non-small Cell Lung Cancer acronym: PILOT overallStatus: RECRUITING date: 2024-01-18 date: 2024-12-31 date: 2025-12-31 date: 2024-04-10 date: 2024-04-10 name: The Affiliated Hospital of Qingdao University class: OTHER briefSummary: Explorative study, which evaluates the effect of Tislelizumab combined with chemotherapy in neoadjuvant treatment of stage Ⅲ unresectable non-small-cell lung carcinoma. conditions: Non-small-cell Lung Cancer (NSCLC) studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 30 type: ESTIMATED name: Tislelizumab name: Pemetrexed (Non-squamous NSCLC) or Nab-paclitaxel(Squamous NSCLC) name: Carboplatin or Cisplatin name: Surgery measure: R0 Resection Rate measure: Objective Response Rate (ORR) measure: Resectability Rate measure: Major Pathological Response (MPR) Rate measure: Rate of grade 3 and higher grade treatment-related adverse events measure: Progression-Free Survival (PFS) measure: Pathological Complete Response (pCR) Rate sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: the Affiliated Hospital of Qingdao University status: RECRUITING city: Qingdao state: Shandong zip: 266000 country: China name: Zhe Wu, PhD role: CONTACT phone: +86 17863934867 email: 17863934867@163.com lat: 36.06488 lon: 120.38042 hasResults: False
nctId: NCT06357585 id: SBUBURCUCALİK briefTitle: Providing Web-based Training to Parents Of Children With Leukemia overallStatus: RECRUITING date: 2021-09-24 date: 2024-04 date: 2024-04 date: 2024-04-10 date: 2024-04-10 name: Saglik Bilimleri Universitesi class: OTHER briefSummary: Following and implementing innovations and current developments in care practices for children diagnosed with leukemia and their parents will allow the quality of care to increase. The purpose of this research is to evaluate the effect of web-based education given to parents of children diagnosed with leukemia on their knowledge level, satisfaction and self-efficacy.
The research is a single-blind randomized controlled experimental research type. The research will be conducted in a single center, Ankara Bilkent City Hospital MH4 Children's Hospital Hematology-Oncology Clinics and Leukemia Polyclinic. The population of the research consists of parents of children diagnosed with leukemia between the ages of 2-18 who are followed and treated in the specified places. The sample of the research consists of 72 participants, 36 in the experimental group (the group that received web-supported training) and 36 in the control group (the group that continued routine treatment).
The consent of the parents who meet the research criteria and voluntarily agree to participate in the study will be obtained with the "Informed Voluntary Consent Form" and the parents in both the experimental group and the control group will be given the "Child and Parent Introductory Information Form", "Child with Leukemia Parent Information Level Pre-Test Evaluation Form". ", "Generalized Perceived Self-Efficacy Scale" will be applied. Once the sufficient number is reached, web-based training will be provided to the parents in the experimental group. "Parents of Children with Leukemia Knowledge Level Post-Test Evaluation Form", "Generalized Perceived Self-Efficacy Scale" and "Web-Based Parents of Children with Leukemia Training Satisfaction Evaluation Form" will be applied to the parents who complete the training. No intervention will be made to the parents in the control group, and the children will continue their routine care and treatment process. The "Child with Leukemia Parent Knowledge Level Posttest Evaluation Form" and the "Generalized Perceived Self-Efficacy Scale" will also be applied to the parents in the control group. conditions: Leukemia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Web-based training will be provided to parents in the experimental group, and parents in the control group will continue their routine treatment and care process. primaryPurpose: SUPPORTIVE_CARE masking: SINGLE maskingDescription: Participant blinding was done because the parents who participated in the study voluntarily did not know which group they were in until the end of the study. whoMasked: PARTICIPANT count: 72 type: ESTIMATED name: Web based education name: inactive group measure: Child with Leukemia Parent Knowledge Level Pre-Test Evaluation Form measure: Child with Leukemia Parent Knowledge Level Post-Test Evaluation Form measure: Web-Based Child with Leukemia Parent Education Satisfaction Evaluation Form measure: Generalized Perceived Self-Efficacy Scale measure: Generalized Perceived Self-Efficacy Scale sex: ALL minimumAge: 2 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: University of Health Sciences status: RECRUITING city: Ankara state: Keçiören zip: 06018 country: Turkey name: Burcu ÇALIK BAĞRIYANIK role: CONTACT phone: 05067075349 email: brc_clk@outlook.com lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06357572 id: ENZ13-2024 briefTitle: Real-life Clinical FEIBA Samples Measured Using the Version A of the HemA EnzySystem overallStatus: COMPLETED date: 2024-03-26 date: 2024-03-27 date: 2024-03-27 date: 2024-04-10 date: 2024-04-10 name: Enzyre B.V. class: INDUSTRY name: Instytut Hematologii i Transfuzjologii, Warschau, Poland briefSummary: The goal of this observational study is to assess if the version A of the HemA EnzySystem, a novel portable coagulation testing platform, can be used in patients with hemophilia A treated with Factor VIII Bypassing Agent (FEIBA). The main question\[s\] it aims to answer are:
Participants are asked to fill in a questionnaire regarding their general health and hemophilia treatment. Subsequently, blood will be drawn from the patients before, and at 30, 120, and 240 minutes after FEIBA administration. Whole blood is immediately tested using the Version A HemA EnzySystem, and plasma is generated for testing with the Ceveron s100 (Technoclone). Leftover samples are frozen for later additional coagulation testing. conditions: Hemophilia A With Inhibitor conditions: Hemophilia A studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 6 type: ACTUAL name: Thrombin generation assay (EnzySystem HemA version A - whole blood) name: Thrombin generation assay (Ceveron s100 (Technoclone) - fresh plasma) name: Additional coagulation tests measure: Time between venipuncture and TGA result measure: Agreement between TGA obtained with the EnzySystem HemA version A and conventional TGA results sex: MALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Institute of Hematology and Blood Transfusion city: Warsaw state: Mazowieckie Województwo country: Poland lat: 52.22977 lon: 21.01178 hasResults: False
nctId: NCT06357559 id: OCTA in Myopic CNV briefTitle: OCTA Changes in Choroidal Neovascularization in High Myopia overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2024-09-15 date: 2024-12-01 date: 2024-04-10 date: 2024-04-10 name: Sohag University class: OTHER briefSummary: To Analyze the Ability of Optical Coherence Tomography Angiography ( OCT-A ) to detect the presence of myopic Choroidal Neovascularization and to describe the structural features of Myopic CNV.. conditions: Myopic Choroidal Neovascularisation studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 100 type: ESTIMATED name: OCTA measure: Describing the Choroidal Neovascularization in High Myopic Patients diagnosed by OCTA sex: ALL minimumAge: 10 Years maximumAge: 75 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06357520 id: D6970C00005 briefTitle: A Study to Investigate the Pharmacokinetics of Baxdrostat When Given Alone and in Combination With Itraconazole in Healthy Participants overallStatus: RECRUITING date: 2024-04-16 date: 2024-06-06 date: 2024-06-06 date: 2024-04-10 date: 2024-04-25 name: AstraZeneca class: INDUSTRY briefSummary: The main purpose of this study is to assess the effect of itraconazole on the pharmacokinetic (PK) of baxdrostat. conditions: Healthy Participants studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 14 type: ESTIMATED name: Baxdrostat name: Itraconazole measure: Area Under Plasma Concentration-Time Curve From Time Zero To Infinity (AUCinf) measure: Maximum Observed Plasma Drug Concentration (Cmax) measure: Extrapolated Area Under The Curve From Tlast to Infinity (AUCextr) measure: Area Under Plasma Concentration Curve from Time Zero to the Last Quantifiable Concentration (AUClast) measure: Apparent Total Body Clearance (CL/F) measure: Apparent Volume Of Distribution Based On The Terminal Phase (Vz/F) measure: Terminal Elimination Half-life (t1/2λz) measure: Terminal Rate Constant (λz) measure: Mean Residence Time (MRTinf) measure: Time To Reach Maximum Observed Concentration (tmax) measure: Ratio of Baxdrostat (Baxdrostat + Itraconazole) to Baxdrostat (Alone) Based on Maximum Plasma Concentration (RCmax) measure: Ratio of Baxdrostat (Baxdrostat + Itraconazole) to Baxdrostat (Alone) Based on AUClast (RAUClast) measure: Ratio of Baxdrostat (Baxdrostat + Itraconazole) to Baxdrostat (Alone) Based on AUCinf (RAUCinf) measure: Number of Participants with Adverse Events sex: ALL minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: Research Site status: RECRUITING city: Brooklyn state: Maryland zip: 21225 country: United States lat: 39.23039 lon: -76.60219 hasResults: False
nctId: NCT06357507 id: hayam hamdy briefTitle: Molecular Characterization of Moraxella Catarrhalis From Pneumonic Children at Pediatric Assiut University Hospital acronym: Mcatarrhalis overallStatus: NOT_YET_RECRUITING date: 2024-12-01 date: 2027-12-01 date: 2027-12-20 date: 2024-04-10 date: 2024-04-16 name: Assiut University class: OTHER briefSummary: moraxella catarrhalis is responsible for respiratory tract infection in children and adults with streptococcus pneumonia and haemophilus influenza.Moraxella catarrhalis is gram negative diplococci, non-motile and non spore bearing bacteria. Until, 1995 it was considered as a non pathogenic respiratory tract flora.This bacteria is an important pathogen and a common cause of both upper and lower respiratory tract infections, pneumonia, sinusitis and conjunctivitis in infants, children and in elderly patients. In adults, M. catarrhalis also causes chronic obstructive pulmonary disease (COPD) and pneumonia. However, it is associated with a number of respiratory infections affecting both children and adults, including laryngitis, bronchitis and pneumonia . conditions: Respiratory Tract Infections studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 90 type: ESTIMATED measure: isolation of moraxella catarrhalis measure: detection of virulence genes of moraxella catarrhalis measure: detetion of antibiotic resistance sex: ALL minimumAge: 1 Month stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06357494 id: Thyroid Doppler in Graves' briefTitle: Assessment of Thyroid Doppler Ultrasound in Followup of Pediatric Graves' Disease overallStatus: NOT_YET_RECRUITING date: 2024-04-05 date: 2027-04-05 date: 2028-04-05 date: 2024-04-10 date: 2024-04-10 name: Assiut University class: OTHER briefSummary: All cases of the study will be diagnosed as Graves' by History, examination, laboratory (FT3, FT4, TSH \& TRAbs), X-ray on left wrist for bone age, neck grey scale ultrasonography for thyroid gland size, shape, echotexture, vascularity and nodule characters if present with TIRAD score calculation.
Doppler ultrasound will be done at 0, 12 and 24 months. conditions: Doppler Ultrasound in Follow up of Graves' Patients studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 32 type: ESTIMATED measure: To make follow up of graves disease easier and improve patients adherence to treatment and follow up plan. measure: better control of disease in our patients, less complications, less mortality and better prognosis. sex: ALL minimumAge: 1 Year maximumAge: 18 Years stdAges: CHILD stdAges: ADULT hasResults: False
nctId: NCT06357481 id: SaglikBilimleriU-22-122 briefTitle: Evaluation of Postoperative Pain After Single Visit Retreatment of Symptomatic and Asymptomatic Teeth acronym: Endodontics overallStatus: COMPLETED date: 2023-01-26 date: 2023-01-30 date: 2024-01-28 date: 2024-04-10 date: 2024-04-17 name: Saglik Bilimleri Universitesi class: OTHER briefSummary: Introduction: The aim of this study comparing the post operative pain after the retreatment of asymptomatic and symptomatic teeth that during single visit treatment with rotary and reciprocal nickel titanium files.
Methods: One hundred and forty one patients scheduled for non-surgical endodontic retreatment were included for evaluation. Eighty five patients who needed endodontic retreatment were assingned to 2 groups according to semptomatic or asemptomatic teeth and 4 subgroups with rotary and resiprocal files. Endodontic filling material was removed with One Flare and MicroMega REMOVER files in the retreatment kit. Patients then recorded their postoperative pain on a VAS scale at 24h, 48h, 72h, 7 days and 14 days post-treatment. Results were analyzed using the Shapiro-Wilk, Mann-Whitney U, Kruskal-Wallis, Dunn-Bonferroni and Pearson Chi-square tests. conditions: Post-operative Pain conditions: Retreatment conditions: Symptomatic Periapical Periodontitis conditions: Endodontic Disease conditions: Asymptomatic Periapical Periodontitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Eighty patients who needed endodontic retreatment were assingned to 2 groups according to symptomatic or asymptomatic teeth and 4 subgroups with rotary and resiprocal files. primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 80 type: ACTUAL name: Endodontic Retreatment measure: Post-operative pain sex: ALL minimumAge: 18 Years maximumAge: 67 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hüseyin Gürkan Güneç city: Istanbul state: Uskudar zip: 34450 country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06357468 id: UKGEB003 briefTitle: Analysis of Pain Management and Pain Perception Intrapartum and Postpartum in Women With Vaginal Births in Difference Between Physician-led and Midwife-led Birth overallStatus: RECRUITING date: 2023-01-01 date: 2024-06-30 date: 2024-12-31 date: 2024-04-10 date: 2024-04-10 name: Martin-Luther-Universität Halle-Wittenberg class: OTHER briefSummary: The aim of the analysis is to describe the differences and similarities in obstetric pain management and pain perception intrapartum and postpartum in women with vaginal births in contrast to physician-led births and midwife-led births conditions: Pain, Labor studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 400 type: ESTIMATED name: midwife-led births in low risk women in pregnancy measure: Pain perception measure: Satisfaction with pain therapy measure: Pain perception in women with perineal tear grade III sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University Hospital of Halle status: RECRUITING city: Halle state: Saxony Anhalt zip: 06120 country: Germany name: Marcus Riemer, MD role: CONTACT phone: 03455573946 email: marcus.riemer@uk-halle.de lat: 51.48159 lon: 11.97948 hasResults: False
nctId: NCT06357455 id: Platelet CellSaver Liver trnsp briefTitle: Platelet Count and Function After Usage of Two Different Cell Saver Devices During Liver Transplant Surgery acronym: PLFLTS overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-06-01 date: 2025-06-01 date: 2024-04-10 date: 2024-04-10 name: Eduardo Schiffer class: OTHER name: University Hospital, Geneva name: Insel Gruppe AG, University Hospital Bern briefSummary: Intraoperative cell salvage is commonly used in surgeries that carry a major hemorrhagic risk to reduce the administration of allogeneic red blood cells and thus improve the outcome for the patient. When processing the salvaged blood, however, a large part of the patient's plasma is washed out. This is a disadvantage with regard to an optimal coagulation status after these types of surgeries, especially liver transplantation.
The investigators aim to study the performance of two different cell saver devices regarding preservation of platelet number and function. conditions: Liver Transplant conditions: Hemorrhage, Surgical studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 40 type: ESTIMATED name: Cell Salvage Autotransfusion: SAME™ device name: Cell Salvage Autotransfusion: Autolog™ device measure: Platelet number measure: Platelet function measure: Platelet function measure: Platelet function measure: Platelet function measure: Platelet function measure: Platelet function measure: Blood plasma albumin level measure: Blood hemoglobin level measure: Blood lactate level measure: Free hemoglobin level measure: Anti-Xa activity measure: Number of allogeneic blood products used measure: Number of coagulation concentrates used measure: Amount of autologous blood at the end of the liver transplantation sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Geneva University Hospitals city: Geneva zip: 1211 country: Switzerland name: Eduardo Schiffer, MD role: CONTACT email: eduardo.schiffer@hcuge.ch name: Tony Mouawad, MD role: PRINCIPAL_INVESTIGATOR lat: 46.20222 lon: 6.14569 hasResults: False
nctId: NCT06357442 id: 23-2305 briefTitle: Assessment of Endometrial Thickness Among Adolescent and Young Adult Patients on Estrogen Replacement Therapy Using Daily Oral Micronized Progesterone Versus the Etonogestrel Implant. overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-04 date: 2025-04 date: 2024-04-10 date: 2024-04-10 name: University of Colorado, Denver class: OTHER briefSummary: The goal of this observational study is to compare endometrial stripe thickness in adolescent and young adult (AYA) patients with a uterus on estrogen replacement therapy using oral progesterone versus the etonogstrel implant for endometrial protection.
Researchers will compare the change in endometrial thickness after 6 months of progesterone use to see if there is a significant difference in the mean change between the prometrium and Nexplanon groups. conditions: Primary Ovarian Insufficiency conditions: Hypogonadotropic Hypogonadism conditions: Hormone Replacement Therapy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 34 type: ESTIMATED measure: Mean change in endometrial thickness after 6 months of progesterone therapy measure: Measure the mean endometrial thickness on estrogen replacement therapy measure: Satisfaction of progesterone replacement therapy measure: Bleeding patterns on progesterone replacement therapy measure: Side effects of progesterone replacement therapy measure: Adherence to progesterone replacement therapy measure: Rate of enrollment and attrition measure: Number of patients willing to be randomized in future trial sex: FEMALE minimumAge: 12 Years maximumAge: 25 Years stdAges: CHILD stdAges: ADULT hasResults: False