hackint0sh/New-Dataset huggingface dataset:
* What the reasons for the adopted infant and young child-feeding practices in Slum-dwelling women Participants will be measured for their height and weight, interviewed for Socio-demographic characteristics, birth history of the infant, infant feeding indicators and will be involved in focused group discussions and in-depth interviews to gain understanding into their adopted appropriate and inappropriate feeding practices. conditions: Infant studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 510 type: ESTIMATED name: No intervention measure: Infant and young child-feeding practices among women living in urban areas and slums in Pune and rural areas around Pune, India will have been assessed measure: Reasons for the adopted infant and young child-feeding practices will have been investigated sex: FEMALE minimumAge: 18 Years maximumAge: 49 Years stdAges: ADULT facility: Hirabai Cowasji Jehangir Medical Research Institute status: RECRUITING city: Pune state: Maharashtra zip: 411001 country: India name: Anuradha V. Khadilkar, MBBS,MD role: CONTACT phone: 9850244305 email: anuradhavkhadilkar@gmail.com name: Rubina M. Mandlik, Ph.D. role: CONTACT phone: 9922959588 email: rubymandlik@hotmail.com lat: 18.51957 lon: 73.85535 hasResults: False
nctId: NCT06307938 id: 619020 briefTitle: Circulating Tumor DNA in Patients Summoned for Colonoscopy; - a Liquid Biopsy for Detection, Characterization, Individualized Treatment and Follow-up of Colorectal Cancer acronym: CoLiQ overallStatus: NOT_YET_RECRUITING date: 2025-01 date: 2027-12 date: 2027-12 date: 2024-03-13 date: 2024-03-13 name: Helse Nord-Trøndelag HF class: OTHER name: Norwegian University of Science and Technology briefSummary: CoLiQ is an observational study designed to evaluate the clinical usefulness of circulating tumor DNA (ctDNA) markers found in blood, as a liquid biopsy for diagnosis, prognosis and follow-up of colorectal cancer. The main questions it aims to answer are: 1) Can a panel of ctDNA markers identify CRC patients among the other patients summoned for colonoscopy? and 2) Does the type, number and level of ctDNA markers vary with the subtype and clinical course of CRC? Participants will be asked to answer a questionnaire and give a blood sample at inclusion. In addition, patients with CRC will be asked to give an extra test tube at their routine treatment and follow-up blood sampling. conditions: Colorectal Cancer conditions: Colorectal Adenoma studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 3000 type: ESTIMATED name: liquid biopsy measure: Colorectal cancer measure: Colorectal adenoma measure: Inflammatory bowel disease measure: Recurrence measure: Death measure: Treatment response sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06307925 id: HC010-001 briefTitle: A Phase I Study to Evaluate the Safety, Pharmacokinetics and Antitumor Activity of HC010 in Patients With Advanced Solid Tumors overallStatus: RECRUITING date: 2024-03-27 date: 2025-12-31 date: 2025-12-31 date: 2024-03-13 date: 2024-04-10 name: HC Biopharma Inc. class: INDUSTRY briefSummary: This clinical trial is a multicenter, open, single-arm, non-randomized, dose-escalation and dose-expansion, phase I clinical study in patients with advanced recurrent or metastatic solid tumors.The goal of this study is to evaluate the safety and tolerability of HC010 monotherapy in patients with advanced solid tumors. conditions: Advanced Solid Tumor studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 122 type: ESTIMATED name: HC010 measure: Incidence of dose-limiting toxicity measure: Adverse events measure: serious adverse events measure: Maximum Tolerated Dose measure: Recommended Dose for Phase II Clinical Studies measure: pharmacokinetics:Cmax measure: Objective response rate measure: duration of response measure: progression-free survival measure: overall survival measure: Disease control rate measure: pharmacokinetics:AUC0-last measure: pharmacokinetics:tmax measure: pharmacokinetics:Vd sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sun Yat-sen University Cancer Center status: RECRUITING city: Guangzhou state: Guangdong country: China name: Li Zhang, MD role: CONTACT phone: +86 139 0228 2893 email: zhangli@sysucc.org.cn lat: 23.11667 lon: 113.25 hasResults: False
nctId: NCT06307912 id: 202301 briefTitle: Physiotherapists' Placebo or Nocebo Communication Regarding VR overallStatus: COMPLETED date: 2023-11-01 date: 2023-12-01 date: 2023-12-01 date: 2024-03-13 date: 2024-03-13 name: HAN University of Applied Sciences class: OTHER briefSummary: Rationale: Chronic musculoskeletal pain (CMP) is a common and disabling condition. Physiotherapy is the most frequently administered nonpharmacological treatment option for patients with CMP and recently virtual reality (VR) was introduced in physiotherapy care as a novel treatment modality. Proper communication about physiotherapy treatment (modalities) is important to improve treatment outcomes, by applying placebo effects enhancing communication and avoiding nocebo effects enhancing communication. However, yet is still unknown to what extent this applies to communication of physiotherapists about VR in healthy participants.
Primary study parameters: The primary study parameters are treatment credibility and treatment expectation. Treatment credibility and treatment expectations will be measured using the Dutch credibility and expectancy questionnaire (CEQ). conditions: Communication studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 126 type: ACTUAL name: Video placebo communication name: Video nocebo communication measure: Change in treatment expectancy measured using the Credibility and Expectancy Questionnaire (CEQ) measure: Change in treatment credibility measured using the Credibility and Expectancy Questionnaire (CEQ) measure: Change in openness to VR measured using a single question sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: HAN University of Applied Sciences city: Nijmegen state: Overijssel zip: 6525EN country: Netherlands lat: 51.8425 lon: 5.85278 hasResults: False
nctId: NCT06307899 id: E-77082166-302.08.01-639069 briefTitle: Immediate Effects of Different Stretching Methods for Pectoralis Minor Muscle overallStatus: RECRUITING date: 2023-09-11 date: 2024-07-03 date: 2024-09-04 date: 2024-03-13 date: 2024-03-13 name: Gazi University class: OTHER briefSummary: The aim of our study is to compare the effects of different stretching methods for the pectoralis minor (PM) muscle on scapula position, PM muscle length and scapular muscle activation in individuals with shoulder protraction. Unilateral corner stretching, manual stretching and proprioceptive neuromuscular facilitation (PNF) stretching methods will be applied randomly, 2 days apart, to volunteer individuals who agree to participate in our study. Three different stretching methods (unilateral corner stretching, manual stretching and PNF stretching) will be applied to individuals randomly, 48 hours apart, and PM length, PM index, scapula upward rotation and EMG values will be recorded by a blind evaluator before and after the stretching application. conditions: Rounded Shoulder Posture studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 25 type: ESTIMATED name: Unilateral Corner Stretch name: Manual Stretching name: PNF Stretching measure: Pectoralis Minor Length measure: Pectoralis Minor Length measure: Pectoralis Minor Index measure: Pectoralis Minor Index measure: Scapula Upward Rotation Measurement measure: Scapula Upward Rotation Measurement measure: EMG Analysis measure: EMG Analysis sex: ALL minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: Gazi University status: RECRUITING city: Ankara state: Çankaya zip: 06490 country: Turkey name: Tuğçe Çoban, MSc role: CONTACT phone: +905454098540 email: fzttugce@yahoo.com lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06307886 id: GaziosmanpasaTREHSs briefTitle: Comparison of Five-year Survival and Disease-free Survival in Patients Diagnosed With Endometrium Cancer Who Underwent Total Laparoscopic Hysterectomy With and Without Uterine Manipulator overallStatus: RECRUITING date: 2023-09-01 date: 2024-09-01 date: 2028-09-01 date: 2024-03-13 date: 2024-03-13 name: Gaziosmanpasa Research and Education Hospital class: OTHER_GOV briefSummary: Comparison of five-year survival and disease-free survival in patients diagnosed with endometrium cancer who underwent total laparoscopic hysterectomy with and without a uterine manipulator conditions: Endometrial Cancer studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 108 type: ESTIMATED name: Patients Diagnosed With Endometrium Cancer Who Underwent Total Laparoscopic Hysterectomy With manipulator name: lPatients Diagnosed With Endometrium Cancer Who Underwent Total Laparoscopic Hysterectomy without uterine manipulator measure: five year survival in patients diagnosed with endometrial cancer measure: disease-free survival in patients diagnosed with endometrial cancer sex: FEMALE minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Gaziosmanpasa Training and research hospital status: RECRUITING city: Istanbul country: Turkey name: Süleyman Salman, Professor role: CONTACT phone: +905059345470 email: sleymansalman@gmail.com name: Havva Betül Bacak, Specialist role: CONTACT phone: +905333610088 email: hbbacak90@gmail.com name: Fatma Ketenci Gencer, Associate Professor role: SUB_INVESTIGATOR lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06307873 id: GaziosmanpasaTREH. briefTitle: Comparison of the Effects of Sacrospinous Fixation and V-notes Lateral Suspension Operations overallStatus: RECRUITING date: 2023-09-01 date: 2024-09-01 date: 2025-09-01 date: 2024-03-13 date: 2024-03-13 name: Gaziosmanpasa Research and Education Hospital class: OTHER_GOV briefSummary: Comparison of the effects of sacrospinous fixation and v-notes lateral suspension operations on anatomical recovery, effectiveness and quality of life in a training and research hospital gynecology and obstetrics clinic. conditions: Genital Prolapse, Unspecified studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 70 type: ESTIMATED name: pre and post operative POP-Q results name: pre and post operative PİSQ-12 results measure: Pre and post operative assessment of POP-Q measurements measure: Pre and post operative assessment of Pelvic Organ Prolapse / Incontinence Sexual sex: FEMALE minimumAge: 35 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Gaziosmanpasa Training and Research Hospital status: RECRUITING city: Istanbul country: Turkey name: Süleyman Salman, Professor role: CONTACT phone: +905059345470 email: sleymansalman@gmail.com name: Havva Betül Bacak, Specialist role: CONTACT phone: +905333610088 email: hbbacak90@gmail.com name: Fatma Ketenci Gencer, Associate Professor role: SUB_INVESTIGATOR lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06307860 id: 15270977512@163.com briefTitle: Comparison of Different Ablation Surgeries on Left Atrial Reverse Remodeling in Patients With Atrial Fibrillation overallStatus: RECRUITING date: 2022-06-01 date: 2024-06-30 date: 2025-03-01 date: 2024-03-13 date: 2024-03-15 name: Yun Wan class: OTHER briefSummary: The goal of this Ambispective cohort Study is to compare in patients with paroxysmal atrial fibrillation undergo pulse field ablation and radiofrequency ablation, respectively. The main question it aims to answer are:Comparison of the therapeutic effects of pulse field ablation and traditional thermal ablation on patients with paroxysmal atrial fibrillation and postoperative left atrial reverse remodeling.Participants will Perform pulse field ablation or radiofrequency ablation according to different groups, and cooperate to complete outpatient follow-up 6 months after surgery. conditions: Atrial Fibrillation studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: OTHER count: 120 type: ESTIMATED name: pulsed field ablation name: radiofrequency ablation measure: Recurrence rate of atrial arrhythmias measure: Left atrial end diastolic diameter measure: p wave dispersion measure: Pulmonary vein stenosis rate measure: Postoperative complications sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ganzhou People's Hospital status: RECRUITING city: Ganzhou state: Jiangxi zip: 341000 country: China name: Wan Yun, Bachelor role: CONTACT phone: 15270977512 email: 15270977512@163.com name: Luo Jun, doctor role: CONTACT phone: 13970107015 email: luojun1966@163.com hasResults: False
nctId: NCT06307834 id: 26760 id: 24POST1194772 type: OTHER_GRANT domain: American Heart Association (AHA) briefTitle: Restoring Grasp Ability in Stroke Survivors Through MI-Based Training overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-06-30 date: 2025-12-31 date: 2024-03-13 date: 2024-03-13 name: North Carolina State University class: OTHER briefSummary: Stroke is a leading cause of disability. Most stroke survivors face challenge in using their arm and hand to carry out daily task, such as grasping or holding objects. This issue makes it tough for nearly 65% of stroke survivors to return to work and take care of themselves. The cause of their disability is changes in their brain's activity patterns of the motor cortex area. Traditional therapy does not directly alter these brain changes, which makes it less effective. As a way to help stroke survivors, people are looking into ways to train the brain directly. A method they found is motor imagery, which involves mental practicing of a task. Studies suggest that this type of training can potentially alter the brain's patterns, which can be seen through EEG. An EEG shows a fixed pattern during movement, called SMR (sensory motor rhythm). Studies have found that people can learn to control this SMR through mental practice of a task. The SMR changes in a similar way during both movement and motor imagery. Therefore, mental practice of hand tasks can lead to improvement in actual hand movements. It has already been shown that stroke survivors can open their hands more easily after receiving SMR training. Along with that, they also have trouble to hold and release objects. SMR training may be able to address these issues by changing brain patterns. But it is not clear yet if SMR training can improve all three stages of grasping (open, close, release), and to what extent it can enhance overall hand function.
This study plans to include 20 adults who have experienced a stroke and have ongoing problems with moving their hands. Half of these participants will take part in a training in which they will learn to control their SMR for three distinct hand tasks (open, close, and release). The first session will be followed by eight training sessions. To guide users toward specific changes in EEG activity, we will provide visual feedback in training. As soon as an appropriate EEG change is made, a hand exoskeleton will help them open and close their hand. The other group of 10 patients will have traditional therapy. They will do 9 sessions of hand exercises. During and after the training, we will test both groups to see how well their hand function improved. The result will help us determine which training method is better for stroke survivors. conditions: Stroke studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 20 type: ESTIMATED name: Neurofeedback - based therapy name: Standard hand exercise therapy measure: Change of Box & Block test (BBT) measure: Change of Action Research Arm Test (ARAT) measure: Change of Wolf Motor Function Test (WMFT) sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hand Rehabilitation Lab city: Raleigh state: North Carolina zip: 27695 country: United States name: Rinku Roy, PhD role: CONTACT phone: 212-731-4114 email: rroy2@ncsu.edu name: Derek G Kamper, PhD role: CONTACT phone: 9195154411 email: dgkamper@ncsu.edu lat: 35.7721 lon: -78.63861 hasResults: False
nctId: NCT06307821 id: WK2024002 briefTitle: the Role of Probiotic in Protein Metabolism overallStatus: RECRUITING date: 2024-03-25 date: 2024-06-25 date: 2024-07-30 date: 2024-03-13 date: 2024-04-09 name: Wecare Probiotics Co., Ltd. class: INDUSTRY briefSummary: This study investigates the functional effects of probiotics on athletes by administering Weizmannella coagulans BC99 for six weeks. It aims to assess the probiotic's influence on skeletal muscle content, athletic performance, and protein digestion and metabolism. This is achieved by monitoring changes in digestive enzymes, amino acids, body composition, and hormone levels. The research seeks to offer a theoretical foundation for optimizing athletes' training and nutrition strategies and suggests the potential of probiotics in enhancing nutrient absorption and utilization, particularly in individuals with compromised digestive capabilities. conditions: Healthy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Double（Participant,Investigator） whoMasked: PARTICIPANT count: 70 type: ESTIMATED name: Probiotic measure: Digestibility and absorption of dietary protein sex: ALL minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: Henan University of Science and Technology status: RECRUITING city: Luoyang state: Henan zip: 471000 country: China name: Ying Wu, Dr. role: CONTACT phone: +86 18639283502 email: wuying2000@126.com lat: 34.68361 lon: 112.45361 hasResults: False
nctId: NCT06307808 id: Vitamin briefTitle: Viral Immunity in Solid Organ Transplant Recipients: Monitoring Of The Response To Hepatitis B Booster Vaccination acronym: VITAMIN overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2025-09-30 date: 2025-10-01 date: 2024-03-13 date: 2024-03-13 name: University Hospital, Grenoble class: OTHER name: National Agency for Research on AIDS and Viral Hepatitis (ANRS) briefSummary: Solid Organ Transplantation (SOT) is made possible by the use of a lifelong immunosuppressive treatment. This treatment limits the response of the immune system, enabling long-term survival of the transplanted organ, but also leading to weaker anti-infectious responses.
In order to provide a detailed picture of the immune response, we will investigate the usual serological response (anti-HBs antibodies), but also the cellular memory (both T and B) using ELISpot assays and flow-cytometry, over a 6 months period following booster vaccination. conditions: HBV conditions: Kidney Transplantation conditions: Liver Transplantation studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 66 type: ESTIMATED name: Tacrolimus name: Belatacept measure: Titer of anti-HBs ELISA antibody measure: Number of anti-HBs memory B cells sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Grenoble University Hospital city: Grenoble state: Aura zip: 38043 country: France name: Pr Thomas Jouve role: PRINCIPAL_INVESTIGATOR lat: 45.16667 lon: 5.71667 hasResults: False
nctId: NCT06307795 id: ANS014004-I-US-01 briefTitle: A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-04 date: 2027-10 date: 2024-03-13 date: 2024-03-13 name: Avistone Biotechnology Co., Ltd. class: INDUSTRY briefSummary: This is a Phase 1, first-in-human, open-label, multi-center study with the aim of exploring the safety, tolerability, PK, and preliminary anti-tumor activity of ANS014004 as a single agent in participants with locally advanced or metastatic solid tumors. conditions: Locally Advanced or Metastatic Solid Tumors studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 63 type: ESTIMATED name: ANS014004 measure: Incidence of Adverse Events (AEs) measure: Incidence of Serious Adverse Events (SAEs) measure: Incidence of dose-limiting toxicities (DLT) as defined in the protocol measure: Incidence of baseline laboratory finding, ECG and vital signs changes measure: Proportion of patients with radiological response (ORR) measure: Objective Response Rate (ORR) measure: Duration of Response (DoR) measure: Disease Control Rate (DCR) measure: Progression free Survival (PFS) measure: Overall Survival (OS) measure: Pharmacokinetics of ANS014004: Plasma PK concentrations measure: Pharmacokinetics of ANS014004: Area under the concentration time curve (AUC) measure: Pharmacokinetics of ANS014004: Maximum plasma concentration of the study drug (C-max) measure: Pharmacokinetics of ANS014004: Time to maximum plasma concentration of the study drug (T-max) measure: Pharmacokinetics of ANS014004: Clearance measure: Pharmacokinetics of ANS014004: Half-life sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sarah Cannon Research Institute city: Denver state: Colorado zip: 80218 country: United States name: MD role: CONTACT lat: 39.73915 lon: -104.9847 facility: Advent Health city: Orlando state: Florida zip: 32804 country: United States lat: 28.53834 lon: -81.37924 facility: The University of Texas - MD Anderson Cancer Center city: Houston state: Texas zip: 77030 country: United States lat: 29.76328 lon: -95.36327 facility: NEXT Oncology, Virginia city: Fairfax state: Virginia zip: 22031 country: United States lat: 38.84622 lon: -77.30637 facility: Univ. of Washington Medical Center city: Seattle state: Washington zip: 98109-1024 country: United States lat: 47.60621 lon: -122.33207 hasResults: False
nctId: NCT06307782 id: 12833 briefTitle: The Effect of Oral Whey Consumption on Insulin Resistance, Cortisol, Crp, Albumin Level and Healing Quality Before Total Hip Arthroplasty acronym: WHEY THA overallStatus: ACTIVE_NOT_RECRUITING date: 2023-06-25 date: 2024-12-30 date: 2024-12-30 date: 2024-03-13 date: 2024-03-13 name: TC Erciyes University class: OTHER briefSummary: Purpose: It was planned to determine the effect of oral whey given before total hip arthroplasty (THA) on postoperative insulin resistance, cortisol, CRP((C reactive protein), albumin level and healing quality.
Design: It was planned as Randomized Controlled. Method: Research: The study is planned to include individuals aged 50-70, who are planned for THA in the orthopedics and traumatology clinic of a public hospital, who have undergone spinal anesthesia, who have BMI \<40 and ASA (American Society of Anesthesiologists)1,2,3. Individuals with endocrine or renal disorders or allergies to whey will be excluded from the study. It was planned to include at least 60 patients in the study (30 in the intervention group, 30 in the control group). It is planned to use the Patient Introduction Information Form, Physiological Measurements Chart (vital findings (blood pressure, pulse, respiratory SpO2 (pulse oximetry) value), blood glucose, cortisol, CRP and albumin value and insulin resistance) and postoperative recovery quality scale in data collection. The intervention group will be given 600 ml of oral whey 6 hours before the surgery, and the control group will be allowed to drink 600 ml of drinking water 6 hours before the surgery. 3ml of blood will be taken for blood glucose, CRP, cortisol, albumin and insulin resistance values 24 hours before the surgery, just before entering the surgery and 24 hours after the surgery. The first part of the healing quality scale is planned to be evaluated immediately before the surgery, and the second part 24 hours after the surgery.