* Scores in epilepsy severity. Participants will be randomized in a cross-over, and will receive 10 days of tDCS or Sham. Each day will allow 2 periods of 20 minutes stimulation separated by 20 minutes off (with 40 minutes of cathodal stimulation total). conditions: Epilepsy conditions: Drug Resistant Epilepsy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 60 type: ESTIMATED name: transcranial direct current stimulation measure: To obtain a significant seizure frequency change at the end of tDCS sessions compared to the seizure frequency calculated in the pre-treatment period of reference. measure: To obtain a significant seizure frequency change at the end of tDCS sessions compared to the seizure frequency calculated in the pre-treatment period of reference. measure: To obtain a significant seizure frequency change at the end of tDCS sessions compared to the seizure frequency calculated in the pre-treatment period of reference. measure: To obtain a significant seizure frequency change at the end of tDCS sessions compared to the seizure frequency calculated in the pre-treatment period of reference. measure: Evaluation of the number of responders (defined as patient with >50% of seizure reduction) measure: Evaluation of the number of responders (defined as patient with >50% of seizure reduction) measure: Evaluation of the number of responders (defined as patient with >50% of seizure reduction) measure: Evaluation of the number of responders (defined as patient with >50% of seizure reduction) measure: Evaluate the number of seizure-free patients measure: Evaluate the number of seizure-free patients measure: Evaluate the number of seizure-free patients measure: Evaluate the number of seizure-free patients measure: Quality of life after stimulation sessions with the baseline period measure: Quality of life after stimulation sessions with the baseline period measure: Quality of life after stimulation sessions with the baseline period measure: Quality of life after stimulation sessions with the baseline period measure: Evaluation of the change in seizure severity measure: Evaluation of the change in seizure severity measure: Evaluation of the change in seizure severity measure: Evaluation of the change in seizure severity measure: Changes in psychiatric comorbidities measure: Changes in psychiatric comorbidities measure: Changes in psychiatric comorbidities measure: Changes in psychiatric comorbidities measure: Safety assessment and possible side effects measure: Safety assessment and possible side effects measure: Safety assessment and possible side effects measure: Safety assessment and possible side effects measure: Compare brain functional connectivity before and after tDCS treatment measure: Evaluation of the impact of tDCS on interictal epileptic spikes (IESs) measure: Evaluation of the impact of tDCS on interictal epileptic spikes measure: Evaluation of the impact of tDCS on interictal epileptic spikes measure: Evaluation of the impact of tDCS on interictal epileptic spikes measure: Evaluation of the impact of tDCS on interictal epileptic spikes sex: ALL minimumAge: 9 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Service de Neurophysiologie Clinique de l'Enfant et de L'Adulte, Pôle de Neurosciences Cliniques city: Bordeaux zip: 33000 country: France name: Jerome Aupy role: CONTACT email: Jerome.aupy@chu-bordeaux.fr lat: 44.84044 lon: -0.5805 facility: Département Neurologie Fonctionnelle et Epilepsie, Hôpital neurologique - Hospices Civils de Lyon city: Bron zip: 69677 country: France name: Sylvain Rheims role: CONTACT email: Sylvain.rheims@chu-lyon.fr lat: 45.73333 lon: 4.91667 facility: Service de Neurophysiologie clinique - Hôpital Roger Salengro, CHU Lille city: Lille zip: 59037 country: France name: Philippe Derambure role: CONTACT email: Philippe.Derambure@chru-lille.fr lat: 50.63297 lon: 3.05858 facility: Service Epileptologie et Rythmologie Cérébrale, Hôpital La Timone city: Marseille zip: 13005 country: France name: Fabrice Bartolomei role: CONTACT email: Fabrice.bartolomei@ap-hm.fr lat: 43.29551 lon: 5.38958 facility: Service de Neurophysiologie clinique - GHU Psychiatrie et Neurosciences Sainte-Anne city: Paris zip: 75014 country: France name: Martine Gavaret role: CONTACT email: m.gavaret@ghu-paris.fr lat: 48.85341 lon: 2.3488 facility: Service de Neurologie - CHU de Rennes - Hôpital Pontchaillou city: Rennes zip: 35033 country: France name: Anca Nica role: CONTACT email: Anca.nica@chu-rennes.fr lat: 48.11198 lon: -1.67429 facility: Explorations neurophysiologiques - Pôle neurosciences, CHU de Toulouse, Hôpital Pierre Paul Riquet city: Toulouse zip: 31059 country: France name: Luc Valton role: CONTACT email: valton.l@chu-toulouse.fr lat: 43.60426 lon: 1.44367 hasResults: False