hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06325670 id: 23/50374 briefTitle: Type 2 Diabetes and Binge Eating Disorder (BED) overallStatus: RECRUITING date: 2024-02-23 date: 2024-12 date: 2025-06 date: 2024-03-22 date: 2024-03-22 name: Odense University Hospital class: OTHER name: Jascha Fonden name: Independent Research Fund Denmark briefSummary: The goal of this research project is to improve the treatment of individuals living with both type 2 diabetes (T2D) and Binge Eating Disorder (BED). The research hypothesizes that BED treatment will not only improve BED symptoms but also improve T2D severity and associated cardiovascular risk factors. The research involves a multidisciplinary team, including experts in endocrinology, psychology, and eating disorders.
Researchers will compare participants' outcomes before and after the treatment program to assess changes in BED symptoms, T2D severity, and associated cardiovascular risk factors. conditions: Diabetes Mellitus, Type 2 conditions: Binge-Eating Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 64 type: ESTIMATED name: BED treatment name: Waitlist measure: Number of binge eating episodes measure: Binge Eating Disorder Questionnaire measure: Glucose Sensor Data for Blood Glucose Profile measure: HbA1c measure: Eating Disorder Examination Questionnaire (EDE-Q) measure: Major Depression Inventory (MDI) measure: Problem Areas In Diabetes (PAID20) measure: Lipid profile measure: Body Mass Index (BMI) measure: Blood Pressure sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Region Of Southern Denmark Locations status: RECRUITING city: Odense state: Region Of Southern Denmark zip: 5000 country: Denmark name: Pernille Fiil Nybo, Cand.psych. role: CONTACT phone: +45 2042 7108 email: Pernille.Fiil.Nybo@rsyd.dk name: Jakob Linnet, Dr. med., cand.psych. role: CONTACT phone: +45 2913 8045 email: jakob.linnet@rsyd.dk lat: 55.39594 lon: 10.38831 hasResults: False
nctId: NCT06325657 id: C3671032 briefTitle: A Study to Learn About the Vaccine RSVpreF In Pregnant Participants With HIV and Their Infants acronym: MORISOT overallStatus: RECRUITING date: 2024-03-12 date: 2025-06-11 date: 2025-06-11 date: 2024-03-22 date: 2024-04-11 name: Pfizer class: INDUSTRY briefSummary: The purpose of the study is to learn about the safety and immune activity of the RSVpreF vaccine. It will be studied in infants born to mothers living with HIV. These infants may have higher chances of getting sick or dying due to RSV infection. Respiratory Syncytial Virus (RSV) is a common type of virus (germ) that can cause severe illness (airway diseases), where medical help is needed. Vaccines help your body make antibodies which help fight against diseases. The antibodies are substances your body uses to fight off an infection. The antibodies can be passed to the infant through the placenta of the mother.
nctId: NCT06325644 id: 2023H0258 id: CDMRP-PR212399-G type: OTHER_GRANT domain: Departent of Defense briefTitle: Well-Formulated Ketogenic Diet Polycystic Kidney Disease overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2027-04-01 date: 2024-03-22 date: 2024-03-22 name: Ohio State University class: OTHER briefSummary: This is a prospective study to determine ketogenic diet effect on htTKV, GFR, microalbuminuria. This is a single-center study of 20 patients with ADPKD and deemed high risk for progression to ESRD. This determined by combination of features of ADPKD and htTKV as assessed by prior computed tomography (CT) or MRI. Patients will be recruited from the Polycystic Kidney Disease (PKD) Clinic at Ohio State University Wexner Medical Center. Enrolled patients will have MRI for htTKV, urinary studies, blood tests at baseline, 6 months, and 52 weeks. Blood for GFR will be assessed three times over the course of the study including baseline, 6 months, and 1 year. Participants will follow ketogenic diet for 52 weeks. Investigatory diet team will manage the ketogenic diet. conditions: Polycystic Kidney Disease studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: BASIC_SCIENCE masking: NONE count: 20 type: ESTIMATED name: Ketogenic Diet name: Ketone/Glucose Monitoring name: CGM/CKM name: Blood Draw name: Body Composition name: Change in glomerular filtration rate (mg/mmol) via magnetic resonance imaging (MRI) . measure: Finger Stick Beta-Hydroxybutyrate measure: Finger Stick Glucose measure: Blood Pressure sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT typeAbbrev: Prot hasProtocol: True hasSap: False hasIcf: False label: Study Protocol date: 2024-01-07 uploadDate: 2024-03-19T14:40 filename: Prot_000.pdf size: 409140 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2024-01-07 uploadDate: 2024-03-19T14:40 filename: ICF_001.pdf size: 428384 hasResults: False
nctId: NCT06325631 id: Ankara City Hospital Bilkent briefTitle: Comparative Evaluation of the Results of Facet Joint Injections overallStatus: RECRUITING date: 2023-01-02 date: 2024-03-31 date: 2024-04-30 date: 2024-03-22 date: 2024-03-22 name: Oznur Uzun class: OTHER briefSummary: Low back pain affects 60 to 90% of the total population. It is one of the most common causes of disability in adults. Low back pain can be originated from a wide variety of structures, and the facet joint is one of these structures. It is thought that 21 to 41% of low back pain originates from the facet joint. A wide variety of conservative treatments, including intra-articular injections, are used to treat low back pain originating from the facet joint. However, there is still no consensus on the most effective treatment method. With appropriate patient selection, facet joint injections can provide significant improvements in patients' pain scores. After Goldthwait defined the facet joint concept in 1911, Ghormley defined facet joint syndrome in 1933. The source of pain in 40-50% of patients is the lumbar facet joints. Innervation of the lumbar facet joints is provided by the medial branches of the dorsal roots of the spinal nerves. In 1975, Shealy described the coagulation of the articular nerve support of the spinal facet joints with the radiofrequency method. These methods have been further developed over time. The results of facet joint injections are satisfactory in well-selected patient groups. It has been shown that intra-articular steroid injection to the facet joint is superior to systemic steroid use in patients with low back pain. In this study, it was aimed to methodically compare the facet joint injections applied to patients diagnosed with facet syndrome in the outpatient clinic of the Physical Therapy and Rehabilitation Hospital in terms of patient pain scores, application time, effort spent and patient anxiety. Intra-articular injections will be performed under by fluoroscopy or ultrasound guidance or anatomic location. conditions: Low Back Pain, Mechanical conditions: Facet Syndrome of Lumbar Spine studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: SINGLE whoMasked: INVESTIGATOR count: 30 type: ESTIMATED name: Intra-articular injection to lumbar facet joint measure: Visual Analogue Scale sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Ankara Bilkent Şehir Hastanesi status: RECRUITING city: Ankara country: Turkey name: Öznur UZUN, MD role: CONTACT phone: +905052912734 email: soznuruzuns@gmail.com lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06325618 id: 1-10-72-138-23 briefTitle: Lymphedema, Low-grade Inflammation and the Vasculature in Turner Syndrome acronym: TSCOR_V overallStatus: RECRUITING date: 2024-01-08 date: 2027-08 date: 2027-08 date: 2024-03-22 date: 2024-03-22 name: University of Aarhus class: OTHER name: Aarhus University Hospital briefSummary: 100 women with karyotype verified TS, previously examined at 4 study visits during a 19-year period will be asked to participate in a 5th study visit. Healthy age-matched females will be included as controls in a ratio 2:1.
The aim is to examine and quantify the cardiovascular and lymphatic system in women with TS. The investigators will study a possible causal mechanism between the known pathologic phenotype and alterations in these systems to understand, prevent or treat the life-threatening complications in TS. conditions: Turner Syndrome conditions: Cardiovascular Diseases conditions: Lymphedema conditions: Inflammation studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: CROSS_SECTIONAL count: 150 type: ESTIMATED name: No intervention other than obtaining biopsies name: Indocyanine green (ICG) measure: Grade dysfunction of clinical and subclinical lymphedema using Indocyanine Green Lymphography and Magnetic Resonance Lymphangiography. measure: Detecting low-grade inflammation in Turner Syndrome preforming FDG-PET/CT-scans to locate low grade inflammation. measure: Heat maps of the distribution of wall shear stress in the aorta measure: MRI evaluation and description of vascular abnormalities in Turner Syndrome measure: Cardiac MRI to evaluate function measure: Cardiac MRI to evaluate fibrosis of the myocardium measure: Mapping DNA-methylations patterns in multiple tissues measure: Immunologic changes in Turner Syndrome sex: FEMALE minimumAge: 18 Years maximumAge: 100 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Aarhus University Hospital status: RECRUITING city: Aarhus N zip: 8200 country: Denmark name: Line Balsby, MD role: CONTACT phone: +4520461203 email: libals@clin.au.dk name: Claus Gravholt, MD, Prof. role: CONTACT lat: 56.15674 lon: 10.21076 hasResults: False
nctId: NCT06325605 id: GRYY-LL-KJ2022-064 briefTitle: Efficacy and Safety of Bifidobacterium Combined With High-frequency Transcranial Magnetic Stimulation in the Treatment of Adolescent Depression overallStatus: COMPLETED date: 2022-03-01 date: 2022-10-31 date: 2022-10-31 date: 2024-03-22 date: 2024-03-22 name: Zhen-Hong Hu class: OTHER briefSummary: A total of 100 patients with adolescent depression who were admitted to our hospital between March 2022 and October 2022 were selected. On the basis of double blinding, these patients were randomly divided into the observation group(n=50) and the control group(n=50) using a random number table. 5S management method was used in the whole process of treatment to improve the hospital environment, increase the work efficiency and reduce the occurrence of cross infection through the effective implementation of the five steps of sort(Seiri), set in order(Seiton), shine (Seiso), standardize(Seiketsu) and sustain(Shitsuke). conditions: Adolescent Depression studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 100 type: ACTUAL name: Bifidobacterium name: High-frequency rTMS name: Escitalopram Oxalate measure: HAMD-24 scores measure: TNF-α measure: IL-1β measure: IL-6 measure: DA measure: 5-HT measure: COR measure: Serum miR-16 measure: Serum miR-195 sex: ALL minimumAge: 13 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Tangshan Workers' Hospital city: Tangshan state: Hebei zip: 063003 country: China lat: 39.63333 lon: 118.18333 hasResults: False
nctId: NCT06325592 id: REHSIL2023V1.1 briefTitle: Association Between Surgical Timing and Route of Total Hysterectomy After LEEP and Perioperative Risk in Patients With Cervical HSIL overallStatus: COMPLETED date: 2023-10-01 date: 2024-03-01 date: 2024-03-01 date: 2024-03-22 date: 2024-03-22 name: Sichuan Cancer Hospital and Research Institute class: OTHER briefSummary: This study aimed to analyze perioperative information in patients with high-grade squamous intraepithelial lesion (HSIL) undergoing total hysterectomy (TH), offering insights into optimal surgery timing, selecting the operation path, and enhancing surgical operation details. conditions: High-Grade Squamous Intraepithelial Lesions studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 826 type: ACTUAL name: surgical timing and operation path measure: Postoperative fever measure: Postoperative therapeutic use of antibiotics measure: Postoperative complications measure: Postoperative hospitalization days measure: Postoperative hemoglobin measure: Postoperative white blood cell count measure: Postoperative erythrocyte count measure: Postoperative albumin number measure: Postoperative CRP value sex: FEMALE stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Sichuan Cancer Hospital and Research Institute city: Chengdu state: Sichuan zip: 610000 country: China lat: 30.66667 lon: 104.06667 hasResults: False
nctId: NCT06325579 id: AA29411356 briefTitle: Immersive Virtual Reality for Dysphagia acronym: IVRys overallStatus: COMPLETED date: 2021-05-24 date: 2023-02-28 date: 2023-03-31 date: 2024-03-22 date: 2024-03-25 name: Sheffield Hallam University class: OTHER briefSummary: People who have suffered a stroke are at high risk of suffering from oropharyngeal dysphagia with long and intensive exercise programmes. Early access to treatment and engaging therapies is very important for recovery. Immersive virtual reality technology presents an innovative treatment that could help patients improve swallowing. The aim of this study is to improve swallowing in stroke patients using two bespoke immersive virtual reality treatment with real-time feedback. The study consisted in a small feasibility study with stroke patients suffering dysphagia (n = 6, aged of 39 to 80 (M=71.17, SD=15.94). Results obtained through interviews with the patients indicated no discomfort reported during the game. All patients reported enjoying the game and feeling engaged and immersive and four out of six patients reported that they would like to use it every day as part of their Speech and Language therapy. The SALT assistant involved in the study stated that the system had the potential to encourage patients to swallow, being more functional than conventional speech therapy. She identified improvements needed for a better functioning of the VR rehabilitation system for Dysphagia. In a future study, wireless headsets will be used, without a laptop, and it will be important to improve the reliability and design of the strain gauge or innovate in the use of a different technology. conditions: Virtual Reality conditions: Dysphagia conditions: Treatment Compliance studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DEVICE_FEASIBILITY masking: NONE count: 6 type: ACTUAL name: Immersive Virtual Reality for Dysphagia Treatment measure: Feasibility of the system. Semi-structure Interviews with patients and staffs. Qualitative outcomes. measure: Feasibility of the system. Semi-structure Interviews with patients. Quantitative outcomes. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sheffield Hallam University city: Sheffield state: South Yorkshire zip: S1 2NU country: United Kingdom lat: 53.38297 lon: -1.4659 hasResults: False
nctId: NCT06325566 id: MSB-DR004 briefTitle: Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back Pain acronym: HyaluronicAcid overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-08 date: 2027-08 date: 2024-03-22 date: 2024-03-22 name: Mesoblast, Ltd. class: INDUSTRY briefSummary: The primary purpose of this study is to evaluate the efficacy of rexlemestrocel-L+HA compared to control in reducing low back pain at 12 months post-treatment and safety of a single injection of rexlemestrocel-L+HA injected into a lumbar intervertebral disc compared to control through 12 months post-treatment. conditions: Degenerative Disc Disease studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 300 type: ESTIMATED name: Rexlemestrocel-L + HA mixture name: Saline measure: Mean Change From Baseline in Daily Average Low Back Pain at 12 Months Post-treatment Based on Visual Analog Scale (VAS) Score measure: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs) measure: Percentage of 30% VAS Pain Responders at 12 Months Post-treatment measure: Mean Change From Baseline in Quality of Life Measured by Euroqol-5D (EQ-5D) Index Score at 12 Months Post-treatment measure: Percentage of Minimal Pain Responders at 12 Months Post-treatment measure: Mean Change From Baseline in Function as Measured by Oswestry Disability Index (ODI) Questionnaire Score at 12 Months Post-treatment measure: Percentage of Participants With 30% VAS and 10-point ODI Treatment Success at 12 Months Post-treatment measure: Percentage of Participants Who Ceased Opioid Usage at 24 Months Post-treatment sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06325553 id: 022_2566 briefTitle: Incidence of Platelet Refractoriness in Adult Acute Leukemia Patients Receiving Prestorage Filtered Blood and Comparing With Historical Control acronym: PTR overallStatus: RECRUITING date: 2024-03-30 date: 2025-03-30 date: 2026-03-30 date: 2024-03-22 date: 2024-03-22 name: Siriraj Hospital class: OTHER briefSummary: This research project is evaluate the incidence of platelet refractoriness in newly diagnosed acute leukemia patients receiving PFB during induction and first consolidation phase chemotherapy compared to 2 historical control groups which are patients receiving non-leukocyte depleted blood product group and leukocyte depleted blood product group and demonstrate cost-effectiveness of using blood products with filtered process to prevent clinical platelet refractoriness compare with using HLA-matched blood products after platelet refractoriness occurs conditions: Platelet Refractoriness in Adult Acute Leukemia studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 252 type: ESTIMATED measure: Descriptive statistics measure: Inferential statistics sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Siriraj hospital status: RECRUITING city: Bangkok zip: 10700 country: Thailand name: weerapat Owattanapanich, MD role: CONTACT phone: 0891081963 email: weerapato36733@gmail.com name: Phakaporn Chamweha, DR role: CONTACT phone: 06855156615 email: phakaporn.cham@gmail.com lat: 13.75398 lon: 100.50144 hasResults: False
nctId: NCT06325540 id: pulpcapping briefTitle: Clinical Success of Indirect Pulp Capping: 1-Year Follow-Up overallStatus: COMPLETED date: 2023-01-01 date: 2024-02-01 date: 2024-02-15 date: 2024-03-22 date: 2024-03-22 name: Saglik Bilimleri Universitesi class: OTHER briefSummary: The goal of this clinical trial is to compare the clinical success of theracal pt, therabase, and biodentine indirect pulp capping on primary molars with deep dentin caries. Indirect pulp capping was used on the primary molars of the participants with deep dentin caries. It is aimed to compare the success of biodentine, which is considered the gold standard used in capping treatments, and the currently marketed Teracal PT and Therabase materials after 1, 6 months and 1 year, with biodentine and with each other, and find out which material is more successful. conditions: Dentin, Carious conditions: Indirect Pulp Capping studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Indirect pulp capping will be applied to primary molar teeth with deep dentin caries in 3 groups with 3 different materials(biodentine, thermal pt, therabase). primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: patients and the researcher who evaluates the follow-up results of the patients will not know which material was used for indirect pulp coating. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 76 type: ACTUAL name: indirect pulp capping with theracal pt name: indirect pulp capping with therabase name: indirect pulp capping with biodentine measure: successful completion of research measure: unseccessful completion of research sex: ALL minimumAge: 5 Years maximumAge: 9 Years stdAges: CHILD facility: Sağlık Bilimleri Üniversitesi city: Istanbul country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06325527 id: YuGarden-01 briefTitle: Cognitive Impairment Cohort Study of the Elderly Population in YuGarden overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2031-04-01 date: 2031-06-01 date: 2024-03-22 date: 2024-03-22 name: Ruijin Hospital class: OTHER briefSummary: The goal of this prospective observational research with an 8-year follow-up is to study the cognitive changes in the elderly in YuGarden community, Shanghai, China.
* to build a predictive model for the progression of cognitive impairment conditions: Alzheimer Disease conditions: Neurodegenerative Diseases conditions: Cognitive Impairment conditions: Mild Cognitive Impairment studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 1872 type: ESTIMATED measure: Incidence of cognitive impairment measure: The change of Mini-Mental State Examination (MMSE) measure: The change of Barthel Index for Activities of Daily Living (ADL) measure: The change of blood biomarkers measure: The change of urine biomarkers measure: The change of feces biomarkers measure: The change of gingival crevicular fluid biomarkers measure: The change of electroencephalogram (EEG) measure: The change of speech information measure: The change of structural MRI measure: The change of functional MRI measure: The change of magnetic susceptibility measure: The change of perfusion MR imaging measure: Positron emission tomography (PET) sex: ALL minimumAge: 60 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine city: Shanghai state: Shanghai country: China name: Jinwen Xiao role: CONTACT phone: 13917310784 email: jw_xiao78@163.com name: Gang Wang role: PRINCIPAL_INVESTIGATOR lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06325514 id: NA2024 briefTitle: Artificial Intelligence Based Program to Classify Oral Cavity Findings Based on Clinical Image Analysis overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-08-01 date: 2024-09-01 date: 2024-03-22 date: 2024-03-26 name: Cairo University class: OTHER briefSummary: This study aims to develop an AI program that can classify oral findings into Normal/variation of normal or an oral disease by clinical photos analysis, aiding in lowering the percentages of false positive and false negative diagnosis of oral diseases. conditions: Oral Cancer conditions: Oral Lichen Planus conditions: Fordyce Granule conditions: Leukoplakia conditions: Erythroplakia conditions: Leukoedemas, Oral conditions: Lichenoid Reaction studyType: OBSERVATIONAL observationalModel: ECOLOGIC_OR_COMMUNITY timePerspective: CROSS_SECTIONAL count: 241 type: ESTIMATED name: Artificial intelligence based program measure: risk stratification sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06325501 id: AA-2024-1 briefTitle: Misoprostol Versus Oxytocin Infusion On Reducing Blood Loss During Abdominal Myomectomy overallStatus: RECRUITING date: 2024-03-01 date: 2024-12-01 date: 2025-01-01 date: 2024-03-22 date: 2024-03-22 name: Cairo University class: OTHER briefSummary: Uterine leiomyomas, or fibroids, are common benign tumors among women, especially those over 35 years old. They can cause various issues, including heavy menstrual bleeding, anemia, pelvic pain, and pressure symptoms. Surgery is often necessary for symptomatic fibroids, with hysterectomy recommended for women over 40 and myomectomy for those wishing to preserve their uterus. Myomectomy can be performed using different surgical approaches but can be associated with significant morbidity, particularly major blood loss, especially in abdominal myomectomy, where up to 20% of women may require blood transfusion.