hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06295185 id: AJOUIRB-IV-2024-097 briefTitle: Digital Therapeutic Workplace Technology as a Employee Management Tool and Employee's Mental Health Care overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-06-30 date: 2024-07-01 date: 2024-03-06 date: 2024-03-06 name: Ajou University School of Medicine class: OTHER briefSummary: The purpose of the study is to determine whether a digital healthcare app for employee's mental health can effectively improve the mental health of Hisbeans's employees and the managerial performance of Hisbeans, which is represented as a 'social enterprise'. conditions: Depression conditions: Mental Health Issue studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 150 type: ESTIMATED name: application MARO name: Sham application measure: Change in network on the Standard Name Generator Approach scale measure: Change in depression symptoms severity on the Patient Health Questionnaire-9 measure: Change in social capital on the Social Capital Scale measure: Change in perceived workload on the Perceived Workload Scale measure: Change in job self-efficacy on the Job Self-Efficacy Scale measure: Change in sense of meaningfulness for job on the Sense of Meaningfulness for Job Scale measure: Change in work orientation toward his or her job on the Work Orientation Scale measure: Change in sense of psychological safety on the Perception of Psychological Safety Scale of Company Employees measure: Change in firm performance on the Company weekly sales records measure: Change in amsenteeism/leaves on the absenteeism/leave scales for employees with severe mental disabilities measure: Change in stress regulation skill on the Emotional/Cognitive/Behavioral State Questionnaire measure: Change in anxiety symptoms severity on the General Anxiety Disorder-7items scale measure: Change in perceived stress level on the Perceived Stress Scale measure: Change in social functioning on Social Adaptation Self Rating Scale measure: Change in positive psychological capital on Korean version of Positive Psychological Capital Scale measure: Change in Organizational Companionship on Organizational Culture Inventory measure: Change in individual's social network on Lubben Social Network Scale-18 sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06295172 id: LF15_NLF_301 briefTitle: A Study Comparing Lafullen15 and Lafullen for Temporary Nasolabial Fold Improvement overallStatus: NOT_YET_RECRUITING date: 2024-03-29 date: 2025-09-30 date: 2026-04-30 date: 2024-03-06 date: 2024-03-06 name: Samyang Biopharmaceuticals Corporation class: INDUSTRY briefSummary: The objective of this clinical trial is to verify the safety and efficacy of Lafullen15 in the temporary improvement of nasolabial Folds conditions: Nasolabial Folds studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A Randomized, Evaluator-blind, Matched pairs, Prospective, Non inferiority, Confirmatory Study primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 73 type: ESTIMATED name: Lafullen15 name: Lafullen measure: Changes in WSRS at 12 months after the last application of the clinical trial medical device compared to the baseline evaluated by an independent evaluator sex: ALL minimumAge: 19 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06295159 id: MCC-22574 briefTitle: Biomarker Driven Patient Selection Neoadjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma overallStatus: RECRUITING date: 2024-02-28 date: 2027-03 date: 2027-03 date: 2024-03-06 date: 2024-03-13 name: H. Lee Moffitt Cancer Center and Research Institute class: OTHER briefSummary: The purpose of this study is to determine if neoadjuvant (treatment before surgery) immunotherapy treatment based on tumor biomarkers results in better participant outcomes. Immunotherapy is the treatment of disease by using a person's own immune system. conditions: Melanoma Stage III conditions: Melanoma Stage IV conditions: Advanced Melanoma conditions: Melanoma studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 30 type: ESTIMATED name: Nivolumab name: Nivolumab + Relatlimab name: Ipilimumab measure: Pathologic Major Response (pMR) measure: Preoperative Radiologic Response Rate measure: Complete Pathologic Response Rate (pCR) measure: Partial Pathologic Response Rate (pPR) measure: Non-Response Pathologic Response Rate (pNR) measure: Progression Free Survival (PFS) measure: Overall Survival (OS) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Moffitt Cancer Center status: RECRUITING city: Tampa state: Florida zip: 33612 country: United States name: Justin Martin role: CONTACT phone: 813-745-7544 email: Justin.Martin@moffitt.org name: Ahmad Tarhini, MD, PhD role: PRINCIPAL_INVESTIGATOR lat: 27.94752 lon: -82.45843 hasResults: False
nctId: NCT06295146 id: STUDY23050075 briefTitle: Virtual Peer Coaching in Manual Wheelchair Skills overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-12-30 date: 2027-12-30 date: 2024-03-06 date: 2024-03-06 name: University of Pittsburgh class: OTHER briefSummary: The objective of this study is to determine the effectiveness of remote manual wheelchair skills training program. First, peer coaches will be enrolled and trained. Then, trainees will be enrolled into one of three interventions: intervention with remote feedback (Group 1), wait list control group (Group 2), and structured self-study (Group 3). conditions: Wheelchair conditions: Paraplegia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: For trainees, we will use a randomized, single-blinded, two-period cross-over study design for Groups 1 and 2. Participants will complete baseline assessments and then be randomized to either Group 1 or Group 2. After we have completed enrollment for Groups 1 and 2 (N=40 per group) we will enroll participants into Group 3 ( N=40 per group). primaryPurpose: BASIC_SCIENCE masking: SINGLE whoMasked: PARTICIPANT count: 132 type: ESTIMATED name: Intervention A: 1-on-1 wheelchair skills training by a peer coach name: Intervention B: Training via educational videos measure: Capacity, confidence, and performance of wheelchair skills will improve following training measure: Wheelchair Skills Test Questionnaire (WST-Q) improvement from baseline following training measure: Wheelchair Skills Test Questionnaire (WST-Q) improvement from baseline (6 months) measure: Wheelchair Skills Test Questionnaire (WST-Q) improvement from baseline (12 months) measure: Goal Attainment Scale (GAS) improvement from baseline (post training) measure: Craig Handicap Assessment and Reporting Technique Short Form (CHART-SF) Mobility improvement (6 months) measure: Craig Handicap Assessment and Reporting Technique Short Form (CHART-SF) Mobility improvement (1 year) measure: Wheelchair Outcome Measure (WhOM) Satisfaction with Participation in Meaningful Activities after baseline (6 months) measure: Wheelchair Outcome Measure (WhOM) Satisfaction with Participation in Meaningful Activities after baseline (1 year) measure: Life Space Assessment (LSA) improvement from baseline (6 months) measure: Life Space Assessment (LSA) improvement from baseline (1 year) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06295133 id: PROMESS - STRESS briefTitle: Preventive Remediation of Stress for Optimal MEdical StudentS overallStatus: RECRUITING date: 2023-11-11 date: 2024-09-30 date: 2024-09-30 date: 2024-03-06 date: 2024-03-06 name: Research on Healthcare Performance Lab U1290 class: OTHER briefSummary: Medical students are subjected to a high competitive pressure throughout their curriculum. High levels of stress are associated with a deterioration in quality of life and learning abilities.
nctId: NCT06295120 id: 362-1 briefTitle: The Optimal Antibiotic Treatment Duration for Community-acquired Pneumonia in Adults Diagnosed in General Practice in Denmark (CAP-D) acronym: CAP-D overallStatus: RECRUITING date: 2023-11-13 date: 2024-12-31 date: 2024-12-31 date: 2024-03-06 date: 2024-03-20 name: Research Unit for General Practice in Aalborg class: OTHER briefSummary: The aim of this randomised controlled trial is to identify the optimal treatment duration with phenoxymethylpenicillin for community-acquired pneumonia diagnosed in general practice.
Consenting patients who meet all the eligibility criteria will be randomised (1:1:1:1:1) to either three, four, five, six or seven days of treatment with phenoxymethylpenicillin 1.2 MIE four times daily. conditions: Community-acquired Pneumonia studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 600 type: ESTIMATED name: Phenoxymethylpenicillin 1.2 MIE 4 times daily measure: Treatment failure at day 30 measure: Clinical recovery at day 8 measure: The Acute Respiratory Tract Infection Questionnaire (ARTIQ) score measure: Prolonged antibiotic treatment measure: Change in type of antibiotic measure: Relapse of acute Lower Respiratory Tract Infection (LRTI) measure: Reconsultation measure: New prescriptions within 30 days measure: Hospitalisation measure: Mortality measure: Adverse events measure: Treatment adherence sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Research Unit for General Practice Aalborg status: RECRUITING city: Gistrup zip: 9260 country: Denmark name: Line Maj Jensen role: CONTACT phone: +45 25 69 99 33 email: lmj@dcm.aau.dk lat: 56.9943 lon: 9.99085 hasResults: False
nctId: NCT06295107 id: 2023-00195-01 briefTitle: Reliability of Range of Movement Measurements in Cerebral Palsy overallStatus: RECRUITING date: 2023-10-01 date: 2024-07-01 date: 2024-07-01 date: 2024-03-06 date: 2024-03-06 name: Region Skane class: OTHER briefSummary: The aim is to investigate the inter-rater reliability of passive range of motion (pROM) measurement with goniometer of knee extension and ankle dorsiflexion for children with unilateral spastic cerebral palsy (USCP) and secondary to explore to what extent spasticity influences the reliability. conditions: Cerebral Palsy conditions: Movement Disorders in Children studyType: OBSERVATIONAL observationalModel: CASE_CROSSOVER timePerspective: PROSPECTIVE count: 32 type: ESTIMATED name: Ankle Passive Range of Movement (pROM) name: Knee Passive Range of Movement (pROM) measure: Ankle range of motion measure: Knee range of motion sex: ALL minimumAge: 2 Years maximumAge: 17 Years stdAges: CHILD facility: Children Habilitation Unit status: RECRUITING city: Lund state: Skane zip: 22241 country: Sweden name: Olof Linden, MD role: CONTACT phone: 0046708475690 email: olof.linden@skane.se lat: 55.70584 lon: 13.19321 hasResults: False
nctId: NCT06295094 id: PIPAC-OPC6 briefTitle: The Efficacy of PIPAC and Minimally Invasive Radical Resection in High-risk Gastric Cancer Patients. acronym: EPICURE overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2027-01 date: 2028-01 date: 2024-03-06 date: 2024-03-06 name: Odense University Hospital class: OTHER name: Karolinska University Hospital briefSummary: The goal of this randomized clinical trial is to investigate whether pressurized intraperitoneal chemotherapy (PIPAC), delivered immediately after minimally invasive D2 gastrectomy and repeated 6-8 weeks later, improves 12-month peritoneal disease-free survival in patients with high-risk gastric adenocarcinoma when compared to standard treatment. conditions: Gastric Cancer conditions: Chemotherapy, Adjuvant conditions: Peritoneal Metastases conditions: Minimally Invasive Surgical Procedures studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 264 type: ESTIMATED name: Cisplatin name: Doxorubicin measure: Peritoneal disease-free survival measure: Disease-free survival measure: Overall survival measure: Length of stay measure: Postoperative toxicity measure: Postoperative complications measure: Postoperative mortality measure: Rate of positive peritoneal lavage measure: Patient-reported Quality of life measure: Patient-reported Quality of life measure: Number of patients not receiving adjuvant chemotherapy sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: City of Hope city: Duarte state: California zip: 91010 country: United States name: Yanghee Woo, PhD role: CONTACT email: yhwoo@coh.org lat: 34.13945 lon: -117.97729 facility: Odense University Hospital city: Odense C zip: 5000 country: Denmark lat: 55.39594 lon: 10.38831 facility: University Hospital Lille city: Lille country: France name: Clarisse Eveno, PhD role: CONTACT email: clarisse.eveno@gmail.com lat: 50.63297 lon: 3.05858 facility: Charité, University of Berlin city: Berlin country: Germany name: Beate Rau, PhD role: CONTACT email: beate.rau@charite.de lat: 52.52437 lon: 13.41053 facility: Karolinska University Hospital city: Stockholm country: Sweden lat: 59.33258 lon: 18.0649 hasResults: False
nctId: NCT06295081 id: NL79864.091.22 id: 112927 type: OTHER domain: RadboudUMC briefTitle: TREAT Study - Improving the Interpretation of Troponin Concentrations Following Exercise and Their Clinical Significance acronym: TREAT overallStatus: RECRUITING date: 2022-06-15 date: 2024-07-01 date: 2044-07-01 date: 2024-03-06 date: 2024-03-06 name: Radboud University Medical Center class: OTHER name: Maastricht University Medical Center briefSummary: The goal of this observational study is to learn about cardiac biomarker release following exercise in amateur athletes.
Question 2: Is the prevalence of (subclinical) coronary artery disease higher in individuals with high post-exercise cardiac troponin concentrations in comparison to individuals with low post-exercise cardiac troponin concentrations? Hypothesis 2: We hypothesize that athletes with the highest post-exercise cTn concentrations have a higher prevalence of coronary atherosclerosis compared to athletes matched for sex and age with the lowest post-exercise cTn concentrations.
Optional visit 3: a blood sample will be drawn. Visit 4: 10% of participants will undergo a cardiac CT scan to assess the prevalence of (subclinical) coronary artery disease. conditions: Coronary Artery Disease studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 1500 type: ESTIMATED name: Exercise exposure measure: High-sensitivity cardiac troponin I (hs-cTnI) measure: High-sensitivity cardiac troponin T (hs-cTnT) measure: General CT scan data measure: Coronary artery calcification score measure: Coronary stenosis and plaque characteristics measure: Computed tomography derived Fractional Flow Reserve measure: Incidence of mortality measure: Incidence of major adverse cardiovascular events measure: Participant characteristics (personal info) measure: Participant characteristics (baseline measurements) measure: Participant characteristics (Exercise characteristics): measure: Medical History questionnaire, part 1 (general info and cardiovascular complaints) measure: Medical History questionnaire, part 2 (diseases and/or conditions) measure: Medical History questionnaire, part 3 (family history, COVID-19 info and medication use) measure: Exercise History questionnaire, part 1 (exercise history, participation in endurance races and current training status) measure: Exercise History questionnaire, part 2 (strength exercise) measure: Other biomarker concentrations in blood sex: ALL minimumAge: 40 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: RadboudUMC status: RECRUITING city: Nijmegen state: Gelderland zip: 6525 GC country: Netherlands name: Sylvan Janssen, MSc role: CONTACT phone: +31243613416 email: sylvan.janssen@radboudumc.nl name: IKS Integraal kwaliteitssysteem role: CONTACT phone: +31243614894 email: integraalkwaliteitssysteemwetenschappelijkonderzoek@radboudumc.nl lat: 51.8425 lon: 5.85278 typeAbbrev: Prot_SAP_ICF hasProtocol: True hasSap: True hasIcf: True label: Study Protocol, Statistical Analysis Plan, and Informed Consent Form date: 2023-01-16 uploadDate: 2023-04-13T09:57 filename: Prot_SAP_ICF_000.pdf size: 852144 hasResults: False
nctId: NCT06295068 id: PRT-1400-11 briefTitle: Evaluation of ARi With OpSens SavvyWire acronym: ARi overallStatus: RECRUITING date: 2023-11-30 date: 2024-04-30 date: 2024-04-30 date: 2024-03-06 date: 2024-03-06 name: Opsens, Inc. class: INDUSTRY briefSummary: The goal of this observational study is to establish the degree of agreement to Aortic Regurgitation (AR) severity during aortic valve intervention between the Aortic Regurgitation Index (ARi) measured by the Opsens SavvyWire, Echography and Aortography in subjects with severe aortic stenosis (AS) undergoing echo guided valve intervention. The main question it aims to answer is how the ARi measured with the Opsens SavvyWire compared with regurgitation evaluation derived by Echography and Aortography. conditions: Aortic Valve Insufficiency studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30 type: ESTIMATED name: Transcatheter Aortic Valve Replacement (TAVR) name: Balloon Aortic Valvuloplasty (BAV) measure: Correlation of the Aortic Regurgitation Index (ARi) measured with the Opsens SavvyWire compared with regurgitation evaluation derived by Echography and Aortography measure: Correlation of the Time Integration Aortic Regurgitation Index (TIARI) measured using the SavvyWire compare with regurgitation evaluation derived by Echography (TEE/TTE) and Aortography measure: Correlation of the Aortic Regurgitation Index Ratio measured using the Opsens SavvyWire compare with regurgitation evaluation derived by Echography and Aortography sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: AHS Morristown Medical Center status: RECRUITING city: Morristown state: New Jersey zip: 07960 country: United States name: Christine Ciprich role: CONTACT phone: 973-971-7541 email: christine.ciprich@atlantichealth.org name: Philippe Généreux, MD role: PRINCIPAL_INVESTIGATOR lat: 40.79677 lon: -74.48154 hasResults: False
nctId: NCT06295055 id: Dentistry Prince of Songkla briefTitle: Semi-rigid Shell Barrier System for Alveolar Bone Augmentation (SSBS for ABA) acronym: SSBS for ABA overallStatus: RECRUITING date: 2024-01-04 date: 2024-10-31 date: 2025-06-30 date: 2024-03-06 date: 2024-03-06 name: Prince of Songkla University class: OTHER briefSummary: This study aims to compare the clinical outcome before and after augmentation in case series of 10 patients. The main question it aims to answer is Whether the semi-rigid shell system facilitates bone regeneration in moderate to severe alveolar bone defects after 4 months of bone augmentation. Participants with bone defects between 3 to 8 millimeters (moderate to severe bone defect) will be treated with xenograft covered with the semi-rigid shell barrier system as a stage approach technique for implant placement. conditions: Guided Bone Regeneration conditions: Bone Formation conditions: Bone Volume studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Before- after augmentation in patients with alveolar bone defects primaryPurpose: TREATMENT masking: NONE count: 10 type: ESTIMATED name: Ridge augmentation with semi-rigid shell barrier system measure: Bone gain evaluation measure: Biocompatibility evaluation measure: Ridge volume change of alveolar ridge evaluation sex: ALL minimumAge: 20 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Prince of Songkla status: RECRUITING city: Songkhla state: Hatyai zip: 90110 country: Thailand name: panisa tantiwongs role: CONTACT phone: 0824864497 email: k-kampt@hotmail.com lat: 7.19882 lon: 100.5951 hasResults: False
nctId: NCT06295042 id: 32-235 ex 19/20 briefTitle: Complications and Long-term Satisfaction in Autologous vs. Implant-Based Breast Reconstruction overallStatus: COMPLETED date: 2019-10-10 date: 2023-11-28 date: 2024-02-01 date: 2024-03-06 date: 2024-03-06 name: Medical University of Graz class: OTHER briefSummary: Current literature on complications and health-related quality of life in autologous and alloplastic breast reconstruction is inconclusive. Despite the great demand for more in-depth, long-term studies of both techniques, current evidence is low or moderate and there are only few studies focusing on both health-related quality of life and complication rates in the same patient collective.
This study aims at investigating the complex relationship between the occurrence of complications and patient-reported long-time satisfaction in autologous and alloplastic breast reconstruction. conditions: Complications, Postoperative/Perioperative conditions: Quality of Life conditions: Satisfaction, Patient studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 162 type: ACTUAL name: BREAST-Q Questionnaire measure: Complications measure: Health-related quality of life and satisfaction sex: FEMALE minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Medical University of Graz city: Graz zip: 8036 country: Austria lat: 47.06667 lon: 15.45 hasResults: False
nctId: NCT06295029 id: CPA-Z05-ZC-2023-002 briefTitle: Personalized Medication Software for BCL-2 Inhibitor in AML Patients Using Machine Learning and Genomics overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2027-12-31 date: 2027-12-31 date: 2024-03-06 date: 2024-03-06 name: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School class: OTHER briefSummary: Severe neutropenia caused by venetoclax,a B-cell lymphoma-2(BCL-2) inhibitor, is the main cause of venetoclax tapering, drug discontinuation, and treatment delay. This study combines machine learning and genomics, hoping to develop models to predict venetoclax dose in Acute myeloid leukemia(AML) patients and compare the efficacy and safety differences of model-guided individualized medication regimen with current conventional regimen. According to the demographic information, the drug information, the drug concentration of the target patients, the laboratory examination, the single nucleotide polymorphism(SNP) information and the adverse reactions of the AML patients, and the model was constructed through machine learning. conditions: Acute Myeloid Leukemia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 200 type: ESTIMATED measure: Overall survival (OS) measure: Progression-free survival (PFS) measure: Overall adverse event rate measure: Incidence of grade III and above adverse events sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False