hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06260631 id: P.T.REC/012/004807 briefTitle: Efficacy of High-intensity Laser Acupuncture in Patients With Chronic, Non-specific Low Back Pain overallStatus: RECRUITING date: 2024-02-25 date: 2024-08 date: 2024-08 date: 2024-02-15 date: 2024-04-26 name: Cairo University class: OTHER name: King Khalid University briefSummary: The purpose of this study is to investigate the efficacy of high-intensity laser acupuncture on peak torque, power of trunk extensors and flexors, back pain, range of motion, function, and satisfaction in patients with chronic nonspecific low back pain (CNLBP). conditions: Chronic Nonspecific Low-back Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: high-intensity laser acupuncture and exercise therapy program primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: random generator whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: high-intensity laser acupuncture and Exercise therapy program name: Sham laser acupuncture measure: peak torque measure: peak torque measure: Average Power measure: Average Power measure: Pain Intensity measure: Pain Intensity measure: lumbar flexion and extension ROM assessment measure: lumbar flexion and extension ROM assessment measure: Disability measure: Disability measure: patient Satisfaction measure: patient Satisfaction sex: ALL minimumAge: 20 Years maximumAge: 40 Years stdAges: ADULT facility: Doaa Ayoub Elimy status: RECRUITING city: Giza zip: 11251 country: Egypt name: Doaa A Elimy, lecturer role: CONTACT phone: 00201066474654 email: do3aayoub25@gmail.com lat: 30.00808 lon: 31.21093 hasResults: False
nctId: NCT06260618 id: 2021/HRE00065 briefTitle: Effect of Chitodex Gel in Tympanoplasty Surgery overallStatus: RECRUITING date: 2021-11-20 date: 2024-05-13 date: 2024-05-13 date: 2024-02-15 date: 2024-02-20 name: Central Adelaide Local Health Network Incorporated class: OTHER_GOV name: University of Adelaide briefSummary: The general purpose of this study is to compare Chitosan-dextran (Chitodex) gel versus current standard of care, Gelfoam, as a middle ear (ME) and external auditory canal (EAC) packing agent as part of tympanoplasty procedures to close tympanic membrane perforations (TMP). conditions: Tympanic Membrane Perforation conditions: Tympanic Membrane Inflammation conditions: Surgery conditions: Otitis Media studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Single blinded randomised clinical trial primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Masked: The people receiving the treatment/s, The people analysing the results/data Unmasked: The surgeon administering the treatment. whoMasked: PARTICIPANT count: 44 type: ESTIMATED name: Gelfoam name: Chitodex measure: Number of participants with tympanic membrane closure measure: rate of tympanic membrane closure measure: Number of participants with improved hearing measure: Number of participants with improved eardrum function measure: Ease of use of product compared to active comparator - surgeon feedback measure: Time taken to complete surgery measure: Number of Participants with improved quality of life sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Queen Elizabeth Hospital status: RECRUITING city: Adelaide state: South Australia zip: 5011 country: Australia name: Prof Peter John Wormald, MD role: CONTACT phone: +61 8 8222 7158 email: pjwormald@gmail.com name: Emma Barry, BSc (Hons) role: CONTACT phone: +61 8 8222 7158 email: emma.barry@adelaide.edu.au name: Prof Peter John Wormald, MD role: PRINCIPAL_INVESTIGATOR lat: -34.92866 lon: 138.59863 facility: The Memorial Hospital status: RECRUITING city: North Adelaide state: South Australia zip: 5006 country: Australia name: Prof Peter John Wormald, MD role: CONTACT phone: +61 8 8222 7158 email: prwormald@gmail.com lat: -34.90733 lon: 138.59141 hasResults: False
nctId: NCT06260605 id: Burcu Bayrak 1 id: Burcu type: REGISTRY domain: Bayrak briefTitle: Complications of Diabetes With Puzzles acronym: Diabetes with overallStatus: COMPLETED date: 2023-12-19 date: 2024-02-20 date: 2024-03-04 date: 2024-02-15 date: 2024-03-07 name: Bilecik Seyh Edebali Universitesi class: OTHER briefSummary: In this study, it was aimed to investigate the effect of diabetes complications training on endocrine system diseases and nursing care in the Internal Medicine Nursing course on the knowledge level of nursing students. conditions: Diabetes Complications studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 110 type: ACTUAL name: Education measure: Education sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Bilecik Şeyh Edebali University city: Bilecik state: Merkez country: Turkey lat: 40.14192 lon: 29.97932 hasResults: False
nctId: NCT06260592 id: Aysun Acun 4 briefTitle: Ethical Attitude and Humanistic Acting Skills of Intensive Care Nurses overallStatus: RECRUITING date: 2024-02-06 date: 2024-03 date: 2024-03 date: 2024-02-15 date: 2024-02-15 name: Bilecik Seyh Edebali Universitesi class: OTHER briefSummary: Today, rapidly developing technology and changing treatment and care conditions increase the tendency towards ethical values both as an intellectual concept and as a moral guide. The nursing profession, which focuses on people in ethical terms, is also performed by people. This situation brings with it many ethical dilemmas in areas where health care services are provided. In ICUs, long and critical treatments of patients, differences of opinion between the medical team and the institution, non-compliance with patient rights, difficulties in terminal patient care, procedures performed without the patient\'s consent, distribution of limited medical resources, unethical attitudes and attitudes of nurse colleagues, Many issues such as long-term exposure to stressors and constant alarm sounds can cause mental distress and negative emotions in intensive care nurses. One of the effective ways to increase the quality of care provided by nurses is humanistic practice ability. The presence of humanistic practice ability provides more realistic, human-centered nursing care, improves the quality of life of patients, and also positively affects health expenditures. conditions: Humanistic Care Skills studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 400 type: ESTIMATED measure: Ethical compliance of nurses in the intensive care unit measure: Humanistic care skills of nurses in the intensive care unit sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Bilecik Şeyh Edebali University status: RECRUITING city: Bilecik zip: 11000 country: Turkey name: Aysun Acun, PhD role: CONTACT phone: +905072104506 email: aysun.acun@bilecik.edu.tr name: Aysun Acun, PhD role: PRINCIPAL_INVESTIGATOR lat: 40.14192 lon: 29.97932 hasResults: False
nctId: NCT06260579 id: S-number 66153 id: S006722N type: OTHER_GRANT domain: Research Foundation Flanders - SBO project briefTitle: Home-based Exercise and Physical Activity Intervention After Kidney Transplantation: Impact of Exercise Intensity acronym: PHOENIX-Kidney overallStatus: RECRUITING date: 2022-11-14 date: 2025-09-30 date: 2029-12 date: 2024-02-15 date: 2024-02-15 name: KU Leuven class: OTHER name: University Ghent briefSummary: This multicentre two-phased RCT aims to evaluate implementation potential, cost-effectiveness, effectiveness, and the role of exercise intensity of a home-based exercise and physical activity intervention to improve de novo kidney transplant recipients' physical fitness, cardiovascular health, gut microbiome characteristics, and health-related quality of life. The first phase of this study comprehends a six-month exercise training intervention. Patients will be randomized into (i) a sham intervention consisting of low-intensity balance and stretching exercises (LIT), (ii) a moderate-intensity aerobic and strength training intervention (MIT), or (iii) a moderate- and high-intensity aerobic and strength training intervention (MHIT). The second phase of this study comprehends a physical activity maintenance intervention provided to MIT and MHIT but not LIT. A total of 147 de novo kidney transplant recipients will be recruited from two independent Belgian transplant centres i.e. UZ Leuven and UZ Ghent. conditions: Physical Activity conditions: Exercise Training conditions: Kidney Transplantation conditions: Physical Fitness conditions: Cardiovascular Health conditions: Gut Microbiome conditions: Health-related Quality of Life conditions: Implementation conditions: Cost-effectiveness studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Parallel group randomized controlled trial primaryPurpose: OTHER masking: SINGLE maskingDescription: Outcome assessors are blinded to the group allocation of the patients. Due to the nature of the intervention, blinding of the patients is not possible. However, a sham training intervention is provided to the control group. whoMasked: OUTCOMES_ASSESSOR count: 147 type: ESTIMATED name: Exercise/physical activity measure: Changes in peak oxygen consumption (VO2peak) measure: Health-related physical fitness sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: UZ Ghent status: RECRUITING city: Ghent zip: 9000 country: Belgium name: Calders Patrick, PhD role: CONTACT lat: 51.05 lon: 3.71667 facility: UZ Leuven status: RECRUITING city: Leuven zip: 3000 country: Belgium name: Amaryllis Van Craenenbroeck, MD, PhD role: CONTACT lat: 50.87959 lon: 4.70093 hasResults: False
nctId: NCT06260566 id: H-52570 briefTitle: Tolerability of Enteral NAC in Infants overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2027-02 date: 2027-02 date: 2024-02-15 date: 2024-04-15 name: Sanjiv Harpavat class: OTHER name: Baylor College of Medicine briefSummary: Biliary atresia (BA) is a neonatal liver disease characterized by impaired bile flow and is the most common indication for pediatric liver transplantation. BA can be treated with the Kasai portoenterostomy (KP), a procedure that attempts to restore bile flow and slow disease progression. However, success of the KP procedure is quite variable, and lack of adjuvant medical therapies following KP is a major gap in pediatric hepatology.
This study begins to explore oral N-acetylcysteine (NAC) as a potential medical therapy in BA by determining whether an oral formulation can be given to infants. The primary objective is to determine tolerability of the oral NAC formulation. The primary outcome is tolerating at least 3 out of 4 total doses without emesis. The Bayesian Optimal Interval Design (BOIN) trial design will be used to determine the maximum tolerated dose of oral NAC. Our secondary objective is to assess palatability of the oral NAC formulation by comparing facial expressions when taking oral NAC versus other medications commonly given to cholestatic infants. conditions: Biliary Atresia studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: The study consists of two parts:
* Administering applesauce plus NAC (for infants who tolerate applesauce in study days 1-2): In study days 3-4, infants will receive an individualized dose of powdered oral NAC mixed into one infant spoon of applesauce by mouth twice a day for a maximum of four doses of NAC medication. primaryPurpose: OTHER masking: NONE maskingDescription: N/A. No Masking count: 12 type: ESTIMATED name: N-Acetylcysteine measure: No emesis within 30 minutes of administration of at least 3 of 4 total doses of oral NAC measure: Oral NAC palatability compared to clinically indicated medications using the facial expression scale measure: Oral NAC-specific adverse event evaluation sex: ALL minimumAge: 122 Days maximumAge: 273 Days stdAges: CHILD hasResults: False
nctId: NCT06260553 id: SCOG008 briefTitle: Metronomic Oral Vinorelbine Combination With Tislelizumab in EGFR/ALK-negative Advanced NSCLC overallStatus: ENROLLING_BY_INVITATION date: 2024-02-07 date: 2025-02-07 date: 2025-08-07 date: 2024-02-15 date: 2024-02-15 name: Fujian Cancer Hospital class: OTHER_GOV briefSummary: To evaluate the efficacy of metronomic chemotherapy combination with tislelizumab in EGFR/ALK-negative advanced NSCLC patients intolerant to first-line standard chemotherapy. conditions: EGFR/ ALK-negative Advanced NSCLC studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 40 type: ESTIMATED name: tislelizumab and metronomic oral vinorelbine measure: PFS measure: ORR measure: DCR measure: AE sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Fujian cancer hospital city: Fuzhou state: Fujian country: China lat: 26.06139 lon: 119.30611 hasResults: False
nctId: NCT06260540 id: Core Endurance briefTitle: Core Endurance in Healthy Young Adults overallStatus: RECRUITING date: 2024-02-01 date: 2024-02-29 date: 2024-04-29 date: 2024-02-15 date: 2024-03-26 name: Karabuk University class: OTHER briefSummary: This study aimed to examine the effect of core endurance levels on upper extremity function, muscle strength and reaction time in healthy young adults. The "core" region functions as a connection point between the upper and lower extremities and enables the transfer of force from this region to the extremities. This region is a basic structure where the force required for all movements is generated and transmitted from the proximal segments to the distal segments. "Core" stabilization has a significant impact on limb functionality, and stabilization of the proximal segments is necessary to maintain the mobility and function of the distal segments. To establish a stable base during functional activities, the "core" muscles are activated before the upper and lower extremity muscles. This ensures force production and transfer of resulting forces, thus supporting the mobility of the distal segments. Increasing core stabilization increases force production in the extremities, and control of core strength, balance and movement maximizes upper and lower extremity functions. Any impairment in core stabilization reduces the quality of movement and increases the risk of injury to the upper extremity. Therefore, it has been stated that "core" stabilization has a significant effect on athletic performance and upper extremity functions. There are not enough studies in the literature investigating this effect in healthy young adults. Most existing studies focus on the role of core endurance on athlete performance.
The aim of this study is not only to investigate core endurance levels in healthy young adults but also to examine the effect of core endurance levels on upper extremity function, muscle strength and reaction time. conditions: Health Risk Behaviors studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 104 type: ESTIMATED measure: Side bridge test measure: Prone bridge test (plank) test measure: Trunk flexion endurance test measure: Sorensen test measure: Purdue Pegboard test measure: Isometric hand dynamometer for muscle strength measure: Nelson hand reaction test sex: ALL minimumAge: 18 Years maximumAge: 25 Years stdAges: ADULT facility: Karabuk University status: RECRUITING city: Karabuk zip: 78000 country: Turkey lat: 41.20488 lon: 32.62768 hasResults: False
nctId: NCT06260514 id: APR-1051-001 briefTitle: Study of APR-1051 in Patients With Advanced Solid Tumors overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2027-06 date: 2028-06 date: 2024-02-15 date: 2024-02-15 name: Aprea Therapeutics class: INDUSTRY briefSummary: The purpose of this study is to assess the safety and effectiveness of APR-1051 through the performance of a Phase 1, open-label, safety, PK, and preliminary efficacy study of oral APR-1051 in patients with advanced solid tumors. conditions: Advanced Solid Tumor studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 79 type: ESTIMATED name: APR-1051 measure: Treatment-related adverse events measure: Recommended dose of APR-1051 measure: Pharmacokinetics: Cmax/Cmin of APR-1051 measure: Pharmacokinetics: Tmax of APR-1051 measure: Pharmacokinetics: AUC of APR-1051 measure: Pharmacokinetics: t1/2 of APR-1051 sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06260501 id: ATADEK-2023-13/463 briefTitle: Wetting Solution-ideal Body Weight Ratio in Liposuction Procedures overallStatus: COMPLETED date: 2021-09-01 date: 2023-09-30 date: 2023-10-30 date: 2024-02-15 date: 2024-02-15 name: Acibadem University class: OTHER briefSummary: Although the use of wetting solutions during high-volume liposuction is a standard approach, it is unclear how to optimize wetting solutions and components and their effect on postoperative complications.. Since the super-wet technique (aspiration of 1 cc per 1 cc of infiltrate) was introduced in 1986, it has become one of the most frequently applied techniques worldwide . Adrenaline and lidocaine are often added to WS due to their hemostatic and analgesic effects One of the major advantages of super-wet technique is that blood loss is quite low. However, potential cardiovascular side effects of WS and the amounts of epinephrine and lidocaine they contain, such as volume overload, local anesthetic toxicity, hypertension, arrhythmia, and tachycardia, are still a scoop of investigation. In this study, we examined the WS and the medications it contains from a different perspective to understand the possible cause of these adverse outcomes. Despite the most suitable candidates for liposuction are patients with a BMI\<30 kg/m2 and low comorbidity and age, the patient group undergoing liposuction is often obese, and overweight individuals require that obesity-related pathophysiological changes be taken into consideration. Therefore, we analyzed the patients by dividing them into two groups according to the amount of WS applied according to their IBW (WS/IBW≤90ml/kg: group I and WS/IBW\>90ml/kg: group I). In this study we aimed to evaluate the effect of wetting solutions and components calculated according to ideal body weight (IBW) on postoperative complications conditions: Liposuction conditions: Obesity conditions: Postoperative Complications studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: RETROSPECTIVE count: 192 type: ACTUAL name: super-wet technique measure: Mean arterial pressure (MAP) was measured to detect hypertension and hypotension. measure: The Numerical Pain Rating Scale (NRS) was used to assess postoperative pain level sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Acibadem Altunizade Hospital city: Istanbul country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06260488 id: 8925 briefTitle: Histological Segmentation of the Superficial Femoral Artery From Microscan to CT Using Artificial Intelligence acronym: CTPred overallStatus: NOT_YET_RECRUITING date: 2024-02-15 date: 2025-06-15 date: 2025-08-15 date: 2024-02-15 date: 2024-02-15 name: University Hospital, Strasbourg, France class: OTHER briefSummary: The femoropopliteal artery segment (FPAS) is one of the longest arteries in the human body, undergoing torsion, compression, flexion and extension due to lower limb movements. Endovascular surgery is considered to be the treatment of choice for the peripheral arterial disease, the results of which depend on the physiological forces on the arterial wall, the anatomy of the vessels and the characteristics of the lesions being treated. The atheromatous disease includes, in a simple way, 3 categories of plaques: calcified, fibrous, and lipidic. The study of these plaques and their differentiation in imaging and histology in the FPAS has already been the subject of research. To treat them, there are angioplasty balloons and stents with different designs and components, with different mechanical properties and different impregnated molecules.
This microscanner can be used ex vivo. In the framework of a project, the learning algorithm was be créated (Convolutional Neural Networks) to automatically segment microscanner slices: after taking FPAS from amputated limbs, we correlated ex-vivo microscanner images of the arteries with their histology. The correlation was then performed manually between the microscanner images, and the histological sections obtained. the algorithm well be trained on these slices and validated its performance. The validation of the CT and microscanner concordance was the subject of scientific publications. conditions: Peripheral Artery Disease conditions: Femoropopliteal Stenosis studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 20 type: ESTIMATED name: Endovascular surgery measure: Assessing the feasibility of histological segmentation of the superficial femoral artery on preoperative microscanner using artificial intelligence sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06260475 id: IUA - 246-18 briefTitle: IUA Committee Research Project on the Management of TASC C and D Aortoiliac Lesions overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-08-31 date: 2024-12-31 date: 2024-02-15 date: 2024-02-15 name: Universidade do Porto class: OTHER name: Clinical Centre of Serbia name: University of Padova name: University of Bari name: University of Trieste name: University of Nis name: Centro Hospitalar de Vila Nova de Gaia/Espinho name: Hospital Centre Hospitalar de Trás-os-Montes e Alto Douro name: Centro Hospitalar do Porto briefSummary: This study aims to evaluate the clinical, imaging results of endovascular revascularization of the aorto-iliac sector in comparison with aortobifemoral bypass and the hybrid approach, in patients with atherosclerotic disease of the iliac sector classified as type C and D by the TransAtlantic Inter-Society Consensus (TASC II conditions: Aortoiliac Atherosclerosis conditions: Aortoiliac Occlusive Disease conditions: Aortoiliac Atherosclerosis With Gangrene conditions: Aortoiliac Atherosclerosis Without Gangrene conditions: Aortoiliac Obstruction conditions: Peripheral Arterial Disease conditions: Peripheral Vascular Diseases studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 500 type: ESTIMATED name: Aortobifemoral bypass name: aortoiliac stenting measure: Major Amputation measure: Cardiovascular Death measure: acute myorcardial infartion measure: Major Adverse Limb Events measure: Major adverse cardiovascular events measure: Death measure: Intensive care unit instay measure: acute kidney injury (AKI) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Centro Hospitalar Universitário de São João, EPE city: Porto zip: 4200-319 country: Portugal name: Joao Rocha-Neves role: CONTACT phone: +351910486230 email: joaorochaneves@hotmail.com lat: 41.14961 lon: -8.61099 facility: Faculdade de Medicina da Universidade do Porto city: Porto zip: 4200-319 country: Portugal lat: 41.14961 lon: -8.61099 hasResults: False