hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06367023 id: 32-2024 briefTitle: Effectiveness of Brahma Kumaris Raja Yoga Meditation on Quality of Life of Youth in the Deaddiction Center of Biratnagar overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-10-30 date: 2025-03-30 date: 2024-04-16 date: 2024-04-16 name: Manipur International University class: OTHER name: Brahmakumaris briefSummary: Drug addiction is a public health problem, mainly youths are involved in the addiction and the major reason were due to peer pressure. Spiritual meditation is thought to foster a deeper sense of meaning, which creates new sources of positive reinforcement, increasing motivation for alternative behavior patterns, such as entering treatment or maintaining abstinence. Cluster Randomized Control Trial will be performed for 1-year period where mixed method study design will be performed. The major variables will be Anxiety and depression score, Happiness index, Quality of life, Rate of Relapse, Age, Gender, Occupation, Education, Income, Family Size, Family Income, Family support, Social status- High/Middle/Low, History of drug use self, Types of drugs, Duration of usage: Reason of drug use, how they have started, Amount of drugs, Frequency of use, Family history of drug use, Money spent on drugs per month. A modified validated Questionnaire will be used. CRCT will be done by CONSORT Guidelines. A total of 160 samples will be taken, (40 from each center, two were given Meditation intervention and 80 were given standard treatment as a control group) and 16 qualitative interviews will be taken (4 from each center). The intervention will be given for 3 months, for 6 days one hour per day Rajyoga meditation basic course will be provided, followed by a 1-hour daily spiritual lesson, Positive thinking and motivation classes will be provided to the intervention group, and in the control group standard treatment will be given. Follow-up will be done after 1 month of discharge from the rehabilitation centers. Ethical clearance will be taken from the Ethical Review Board (ERB) of the Nepal Health Research Council (NHRC). This study will be useful for developing policy and practice in rehabilitation centers to apply the technique of Rajyoga Meditation in relapse prevention. conditions: Prevalence conditions: Depression conditions: Happiness conditions: Quality of Life conditions: Anxiety studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 160 type: ESTIMATED name: Rajyoga Meditation Practice measure: Anxiety score measure: Depression score measure: quality of life score measure: Rate of Relapse sex: MALE minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Rehabilitation center city: Biratnagar state: Koshi zip: 56613 country: Nepal name: Rajiv Ranjan Karn, MPH role: CONTACT phone: +9779842068053 email: rajiv2061@gmail.com name: Ajaya Bhattarai, PhD role: CONTACT phone: +9779842077434 email: bkajaya@gmail.com lat: 26.45505 lon: 87.27007 hasResults: False
nctId: NCT06367010 id: MR-36-24-010942 briefTitle: Clinical Efficacy of 125I Brachytherapy Combined With Anlotinib in Radioiodine Refractory Thyroid Carcinoma Patients overallStatus: COMPLETED date: 2019-01-01 date: 2024-04-01 date: 2024-04-01 date: 2024-04-16 date: 2024-04-16 name: Jiangxi Provincial Cancer Hospital class: OTHER briefSummary: A retrospective analysis was conducted on patients with radioiodine-refractory thyroid carcinoma (RRTC) who underwent radioactive 125I seed implantation combined with anlotinib from January 2019 to October 2024 at Jiangxi Cancer Hospital. Data on tumor size changes before and after treatment, serological tests (including serum TG, TgAb, CTn, CEA, etc.), changes in patients' pain scores, and side effects were collected to evaluate the clinical efficacy and safety of this therapy. conditions: Thyroid Neoplasms studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 8 type: ACTUAL name: Iodine-125 brachytherapy combine with Anlotinib measure: The CT images were used to measure the change in the maximum diameter of the lesion in millimeters. measure: Serological assessment measure: Use the Numerical Rating Scale (NRS) to record patients' pain scores. measure: Number of participants with treatment-related adverse events as assessed by Common Terminology Criteria for Adverse Events (CTCAE) version 5.0 sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Jiangxi Cancer Hospital city: Nanchang state: Jiangxi zip: 330029 country: China lat: 28.68396 lon: 115.85306 hasResults: False
nctId: NCT06366997 id: CQGOG0207 briefTitle: Diagnosis of Epithelial Ovarian Cancer Using Ovarian Cancer Score (OCS) Test overallStatus: COMPLETED date: 2019-10-09 date: 2023-04-18 date: 2023-05-05 date: 2024-04-16 date: 2024-04-16 name: Chongqing University Cancer Hospital class: OTHER name: Zhejiang Cancer Hospital name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University name: The First Affiliated Hospital of Zhengzhou University name: 3D Medicines Corporation briefSummary: The study is designed to confirm the performance of the 3D Medicines Corporation OCS test in diagnosis of epithelial ovarian cancer in patients with adnexal mass. To this end, blood samples from female patients with adnexal mass required surgical resection from four centers are obtained and analysis in the study. conditions: Epithelial Ovarian Cancer conditions: Adnexal Mass studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 1352 type: ACTUAL measure: the Performance of Discrimination of Benign Disease and Malignant tumors by the OCS Value. sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: No.181, Hanyulu Road, Shapingba District city: Chongqing state: Chongqing zip: 400030 country: China lat: 29.56278 lon: 106.55278 hasResults: False
nctId: NCT06366984 id: Adeel4 briefTitle: Outcome of Plastibell Circumcision Versus Open Method Circumcision overallStatus: COMPLETED date: 2022-01-11 date: 2022-07-11 date: 2022-08-11 date: 2024-04-16 date: 2024-04-16 name: Children Hospital and Institute of Child Health, Lahore class: OTHER briefSummary: To compare the outcomes of plastibell circumcision method with open surgical technique in infants presenting at tertiary care hospital.
Methods This randomized controlled trial (NCT??) was conducted at Pediatric surgery department, the Children's hospital and the University of Child health, Lahore. Study was carried out over a period of six months from 11-01-2022 to 11-07-2022. Non probability, purposive sampling was used. 174 infants presenting for circumcision were admitted and assigned a method of circumcision randomly. They were randomly divided in to 2 groups by using opaque sealed envelope technique. Infants in group A were underwent plastibell circumcision while infants in group B were underwent open technique circumcision. 87 circumcisions were performed by each method. The informed consent was taken from parents for inclusion into the study. All infants were underwent circumcision under local anesthesia as per assigned method. Same preoperative, per-operative, and postoperative care was given to each regardless of the technique. These patients were followed for 3 hours to assess bleeding as per operational definition. Then followed on an outpatient basis every 6th day until complete healing is achieved (30 days).The data regarding age, weight, duration of procedure, wound infection and post circumcision bleeding was recorded in a predesigned performa. (As per operational definition). conditions: Bleeding conditions: Site Infection studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized controll trial primaryPurpose: OTHER masking: SINGLE maskingDescription: outcome assessor is unaware of group allocated whoMasked: OUTCOMES_ASSESSOR count: 174 type: ACTUAL name: plastibell name: open method measure: infection sex: MALE minimumAge: 1 Day maximumAge: 12 Months stdAges: CHILD facility: The Children Hospital city: Lahore state: Punjab zip: 42000 country: Pakistan lat: 31.558 lon: 74.35071 hasResults: False
nctId: NCT06366971 id: auhucgun01 briefTitle: The Effect of Pelvic Proprioceptive Neuromuscular Facilitation Techniques in Patients With Sacroiliac Joint Dysfunction overallStatus: COMPLETED date: 2023-12-01 date: 2024-03-31 date: 2024-03-31 date: 2024-04-16 date: 2024-04-16 name: Biruni University class: OTHER briefSummary: The sacroiliac joint dysfunction (SIJD) which has a widely heterogeneous etiology, may cause impairment of stability, mobility, posture and flexibility as well as pain due to adaptive or pathological biomechanical changes. In 2020, the number of patients with low back pain (LBP) worldwide was more than half a billion and is expected to exceed 800 million by 2050. Although SIJD has been shown to be related with LBP in more than 30% of patients with LBP, SIJD is still often overlooked as a cause of LBP. Once the diagnosis of SIJD is confirmed by physical examination, the first treatment option consists of the use of a nonsteroidal anti-inflammatory drug or physiotherapy approaches. The proprioceptive neuromuscular facilitation (PNF) is a neurophysiological model-based multifaceted exercise method which is widely used in rehabilitation practice. However, despite the major role of SIJD among the causes of LBP, there are limited studies investigating the efficacy of PNF in SIJD and its effectiveness remains unclear. Thus, the aim of this study was to investigate the effect of pelvic PNF techniques on pain, mobility, flexibility, lumbar range of motion, posture, and trunk muscle endurance in patients with SIJD. conditions: Sacroiliac Joint Dysfunction studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 34 type: ACTUAL name: The Patient Education name: The Pelvic Proprioceptive Neuromuscular Facilitation Techniques Training measure: The Level of Low Back Pain measure: Mobility measure: Flexibility measure: Lumbar Range of Motion measure: Posture measure: Trunk Muscle Endurance sex: ALL minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: Istanbul Atlas University city: Istanbul state: Kagıthane zip: 34408 country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06366958 id: Dorsal wrist ganglion briefTitle: Arthroscopic Versus Open Excision of Dorsal Wrist Ganglion overallStatus: NOT_YET_RECRUITING date: 2024-05-02 date: 2025-02-02 date: 2025-04-02 date: 2024-04-16 date: 2024-04-16 name: Assiut University class: OTHER briefSummary: compare recurrence rates after open and arthroscopic excision of dorsal wrist ganglion conditions: Hand Ganglion studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 46 type: ESTIMATED name: excision of dorsal wrist ganglion measure: comparison of recurrence rate after open versus arthroscopic excision of dorsal wrist ganglion measure: compare post operative pain ,range of motion ,hang grip strength and post operative scar after open versus arthroscopic excision of dorsal wrist ganglion sex: ALL minimumAge: 10 Years maximumAge: 70 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06366945 id: SYSKY-2024-157-02 briefTitle: Tirelizumab in Combination With Carboplatin and Polymeric Micellar Paclitaxel for Neoadjuvant Therapy in cN+ HNSCC overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2026-12-30 date: 2029-05-30 date: 2024-04-16 date: 2024-04-16 name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University class: OTHER briefSummary: To explore the efficiency and safety of Tislelizumab combinated with carboplatin and polymeric micellar paclitaxel as a new neoadjuvant treatment regimen for resectable HNSCC patients with clinical positive lymph node metastasis conditions: Head and Neck Squamous Cell Carcinoma conditions: Head and Neck Cancer conditions: HNSCC conditions: Head Cancer Neck studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 85 type: ESTIMATED name: Carboplatin name: Tislelizumab name: Polymeric Micellar Paclitaxel name: Surgical Resection of Primary +/- Neck Dissection name: Post-operative radiation therapy measure: Major pathological response (MPR) rate of metastatic lymph nodes measure: Major pathological response (MPR) rate of primary tumor measure: Event-free survival (EFS) measure: Overall survival（OS） measure: Incidence of treatment-related adverse events measure: EORTC QLQ-C30 measure: pathological downstaging rate measure: Distant metastasis-free survival(DMFS) rate measure: logical regional-free survival(LRFS) rate measure: Correlation between ctDNA dynamic detection and 1-year and 2-year EFS and OS rate after Neoadjuvant immunochemotherapy sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06366932 id: DermAtOmics-II briefTitle: Optimization of Atopic Dermatitis Treatment That Requires Second-line Systemic Therapy Through Predictive Models overallStatus: RECRUITING date: 2023-09-25 date: 2025-09 date: 2025-09 date: 2024-04-16 date: 2024-04-16 name: Instituto de Investigación Hospital Universitario La Paz class: OTHER briefSummary: This is a low-intervention phase IV trial. The main objective is to optimize the treatment of patients with moderate-severe atopic dermatitis that require systemic treatment after failure, intolerance or contraindication to cyclosporine. conditions: Atopic Dermatitis studyType: INTERVENTIONAL phases: PHASE4 allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Phase IV, low-intervention clinical trial to develop prediction models that allow to determine the most appropriate therapeutic strategy in patients diagnosed with atopic dermatitis that need second-line systemic treatment. primaryPurpose: TREATMENT masking: NONE count: 150 type: ESTIMATED name: Second-line systemic treatment name: Folllow-up of second-line systemic treatment already started measure: Percentage of patients with primary non-response to second-line treatment. measure: Percentage of patients achieving EASI-75 measure: Time to treatment failure after week 16 measure: Mean percentage of change in Eczema Area and Severity Index (EASI) score measure: Percentage of change in SCORAD (SCORing Atopic Dermatitis) measure: Improvement of at least 75% in SCORAD (SCORing Atopic Dermatitis) measure: Change of IGA (Investigator Global Assessment) measure: Time to IGA score of 0/1 (Investigator Global Assessment) measure: Change of BSA (Body surface area) measure: Change in NRS measure: Change in RECAP measure: Percentage of patients having a variation of 4 points in their improvement in DLQI measure: Change in POEM (Patient-Oriented Eczema Measure) measure: Rate of adverse events associated to second-line systemic treatment measure: Percentage of patients reaching EASI-90 (Percentage of patients reaching 90 percentage) sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Hospital La Paz status: RECRUITING city: Madrid zip: 28046 country: Spain name: Irene García, MD role: CONTACT phone: +34-912071466 email: irene.ucicec@gmail.com lat: 40.4165 lon: -3.70256 hasResults: False
nctId: NCT06366919 id: DPT/Batch-Fall19/559 briefTitle: Comparison of Effectiveness of Alexander Technique Versus Feldenkrais Technique in Non - Specific Neck Pain Patients overallStatus: ACTIVE_NOT_RECRUITING date: 2024-04-01 date: 2024-05-15 date: 2024-06-15 date: 2024-04-16 date: 2024-04-16 name: Superior University class: OTHER briefSummary: Comparison of Effectiveness of Alexander Technique Versus Feldenkrais Technique in Non - Specific Neck Pain Patients conditions: Neck Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: DIAGNOSTIC masking: NONE count: 44 type: ACTUAL name: Alexander Technique (AT) name: Feldenkrais Technique (FT) measure: Northwick Park Neck Pain Questionnaire measure: REEDCO Posture Assessment and Sleep Quality Scale sex: ALL minimumAge: 20 Years maximumAge: 25 Years stdAges: ADULT facility: Chaudary Muhammad Akram Teaching Hospital, Azra Naheed Medical College, Superior University city: Lahore state: Punjab country: Pakistan lat: 31.558 lon: 74.35071 hasResults: False
nctId: NCT06366906 id: SYSKY-2023-426-01 briefTitle: 10-year Retrospective Study of Oral and Maxillofacial Squamous Cell Carcinoma overallStatus: COMPLETED date: 2023-05-10 date: 2024-02-10 date: 2024-02-10 date: 2024-04-16 date: 2024-04-16 name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University class: OTHER briefSummary: Introduction: The incidence of occult cervical lymph node metastases (OCLNM) is reported to be 20%-30% in early-stage oral cancer and oropharyngeal cancer. There is a lack of an accurate diagnostic method to predict occult lymph node metastasis and to help surgeons make precise treatment decisions.
Methods: A total of 319 patients diagnosed with early-stage OC or OP SCC were retrospectively enrolled and divided into training, test and external validation sets. Traditional radiomics features and DLFs were extracted from their MRI images. The least absolute shrinkage and selection operator (LASSO) analysis was employed to identify the most valuable features. Prediction models for OCLNM were developed using radiomics features and DLFs. The effectiveness of the models and their clinical applicability were evaluated using the area under the curve (AUC), decision curve analysis (DCA) and survival analysis. conditions: HNSCC conditions: AI conditions: Radiomic conditions: MRI studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: RETROSPECTIVE count: 319 type: ACTUAL name: The Resnet50 deep learning (DL) model measure: AUC(the area under the curve) values of the model sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Sun yat-sen memorial hospital city: Guangzhou state: Guangdong zip: 510000 country: China lat: 23.11667 lon: 113.25 facility: Sun yat-sun memorial hospital city: Guangzhou state: Guangdong zip: 510000 country: China lat: 23.11667 lon: 113.25 hasResults: False
nctId: NCT06366893 id: PR(AG)297/2019 briefTitle: Enteral Supplementation With Docosahexaenoic Acid and Arachidonic Acid (DHA-AA) in Preterm Infants overallStatus: RECRUITING date: 2024-03-04 date: 2025-03-04 date: 2025-03-04 date: 2024-04-16 date: 2024-04-19 name: Hospital Universitari Vall d'Hebron Research Institute class: OTHER briefSummary: Docosahexaenoic acid (DHA) and arachidonic acid (AA) have a critical effect on the health and neuronal development of the fetus and newborn. Their deficiency has been associated with increased neonatal morbidity, especially in preterm newborns at birth. Direct DHA supplementation during the first few weeks of life could prevent this deficiency.
The study is a single-center, prospective, randomized, controlled, open-label study involving preterm infants admitted to the Neonatology Department of Vall d'Hebron University Hospital in Barcelona. conditions: Infant, Premature, Diseases studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 80 type: ESTIMATED name: DHA/AA emulsion supplement for preterm infant measure: Percentage comparison of erythrocyte membrane levels of DHA and AA measure: Tolerance of DHA emulsion administration measure: Compare the presence of pathologies in preterm infants between the supplemented group and the control group sex: ALL maximumAge: 7 Days stdAges: CHILD facility: Hospital Materno Infantil Vall d'Hebron status: RECRUITING city: Barcelona zip: 08035 country: Spain name: Félix Castillo Salinas, Dr. role: CONTACT phone: +34 934893899 email: felix.castillo@vallhebron.cat name: Félix Castillo Salinas, Dr. role: PRINCIPAL_INVESTIGATOR lat: 41.38879 lon: 2.15899 hasResults: False
nctId: NCT06366880 id: 2022.HPS.DI.434 briefTitle: Parenteral Nutrition Cycling for Prevention of Cholestatic Syndrome in Newborn overallStatus: RECRUITING date: 2024-03-11 date: 2024-12-15 date: 2025-12-15 date: 2024-04-16 date: 2024-04-16 name: Hospital Pediátrico de Sinaloa class: OTHER_GOV briefSummary: Background: Despite the use of parenteral nutrition cycling (PNC) in neonatal intensive care units (NICU), there is limited evidence regarding the benefits in relation to the nutrición parenteral total (NPT) in term and late preterm infants.
The aim of this randomised controlled trial (RCT) is to evaluate the benefits and risks of PNC AND parenteral nutrition total (NPT) in term and late preterm infants. conditions: Cholestasis in Newborn studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 66 type: ESTIMATED name: Parenteral nutrition cycling measure: Incidence of cholestasis on Day 28 of admission. measure: are total plasma bilirrubine profiles measure: the incidence of hypoglycaemia sex: ALL minimumAge: 1 Hour maximumAge: 28 Days stdAges: CHILD facility: Hospital Pediatrico de Sinaloa status: RECRUITING city: Culiacán state: Sinaloa zip: 80200 country: Mexico name: Ana Karen Camargo Angulo, Dr. role: CONTACT phone: 6681890586 phoneExt: +52 email: anakarencamargo96@gmail.com lat: 24.79032 lon: -107.38782 hasResults: False
nctId: NCT06366867 id: Pro00097579 briefTitle: An Open Platform of Serious Games for Cognitive Intervention overallStatus: RECRUITING date: 2022-08-03 date: 2025-08-01 date: 2025-12-01 date: 2024-04-16 date: 2024-04-16 name: University of Alberta class: OTHER name: Alberta Health services name: CapitalCare briefSummary: Computer games are increasingly utilized as tools for studying cognitive skills, aging, individual differences, and development. They offer a unique advantage by presenting challenges that more closely mirror the complexities and demands of everyday tasks compared to traditional laboratory experiments, clinical tests, and standardized assessments. Our team took an innovative step in this direction by developing a suite of tablet-based games, titled VibrantMinds. These games, varying in type, are designed to measure diverse cognitive indicators, acting as proxies for assessments typically conducted using paper-and-pencil tests in clinical settings.
Building on this foundation, we are now poised to conduct an in-depth investigation into the actual effectiveness of serious computer games (SCGs) for cognitive enhancement and their application in real-world settings for older adults. This next phase of research will leverage the VibrantMinds platform to carry out studies aimed at validating software-defined indicators of cognitive function and measuring the impact of game-based interventions on cognitive abilities, health-related quality of life, and other significant real-life outcomes.