hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06318013 id: 2022-KAEK-15427-04-204-2022101 briefTitle: Perineural and Systemic Dexamethasone Use in Dental Surgeries in Terms of Anesthesia Duration and Postop Complaints overallStatus: RECRUITING date: 2024-03-27 date: 2024-04-15 date: 2024-07-01 date: 2024-03-19 date: 2024-03-29 name: Karamanoğlu Mehmetbey University class: OTHER briefSummary: Participants will be asked to use some medications after the tooth extraction procedure. These drugs can be used in different ways. Investigators plan to monitor the pain, swelling and duration of anesthesia in the body as a result of participants use. conditions: Impacted Third Molar Tooth studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: OTHER count: 60 type: ESTIMATED name: vitality test measure: Swelling measure: Duration of anesthesia measure: Pain Score sex: ALL minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: Karamanoğlu Mehmetbey University Ahmet Keleşoğlu Faculty of Dentistry status: RECRUITING city: Karaman zip: 70100 country: Turkey name: Faruk Ayhan Başçiftçi, Dr role: CONTACT phone: 338-226-2082 email: dis@kmu.edu.tr name: Sümeyye Çelik Özsoy, Dr role: CONTACT phone: 338-226-2082 email: sumeyyecelik@kmu.edu.tr name: Doğan Ilgaz Kaya, Dr role: PRINCIPAL_INVESTIGATOR lat: 37.18111 lon: 33.215 hasResults: False
nctId: NCT06318000 id: SN4/20/22 briefTitle: Physical Activity and Sports for People With Visual Impairments overallStatus: COMPLETED date: 2020-03-01 date: 2022-12-31 date: 2022-12-31 date: 2024-03-19 date: 2024-03-20 name: Józef Piłsudski University of Physical Education class: OTHER briefSummary: Purpose of this study was to assess the relationship between the visual impairment degree and the level of children's fundamental motor skills, balance and bilateral coordination. conditions: Blindness conditions: Visual Impairment studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 76 type: ACTUAL name: Balance test, bilateral coordination test, fundamental motor skills test measure: Center of pressure (CoP) path length was measured measure: Surface area of stabilogram was measured measure: Raw and scale score for each item measure: Qualitative performance criteria (points) measure: Body mass in kg measure: Body height in cm sex: ALL minimumAge: 7 Years maximumAge: 17 Years stdAges: CHILD facility: University of Physical Education city: Warsaw zip: 00-968 country: Poland lat: 52.22977 lon: 21.01178 hasResults: False
nctId: NCT06317987 id: 2068557 id: P50DA054072 type: NIH link: https://reporter.nih.gov/quickSearch/P50DA054072 briefTitle: Addressing Barriers to Care for Substance Use Disorder Pilot Study acronym: ABCSUD Pilot overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-04-02 date: 2025-04-02 date: 2024-03-19 date: 2024-04-19 name: Kaiser Permanente class: OTHER name: National Institute on Drug Abuse (NIDA) name: Stanford University briefSummary: The Addressing Barriers to Care for Substance Use Disorder Pilot (ABC-SUD Pilot) is a randomized pilot study that will precede a larger trial. The ABC-SUD Pilot is a parallel group, cluster-randomized pilot feasibility trial, with clinicians (care coordinators) as the unit of randomization.
The experimental intervention, Care Navigation, will be evaluated for its potential to increase the utilization of substance use disorder treatment among patients who contact the mental health treatment access center. The investigators note that Care Navigation will be delivered by study "care navigators", who are distinct from the health system's care coordinators. conditions: Drug Use Disorders conditions: Illicit Drug Use conditions: Alcohol-Related Disorders studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Care coordinators will be randomized to two parallel groups: usual care (UC; i.e., the comparator group) and usual care plus care navigation (UC + CN; i.e., the experimental group). All care coordinators will continue offering substance use resources and treatment options to patients as usual. Clinicians randomized to UC + CN will be able to offer and refer patients to a care navigator. primaryPurpose: HEALTH_SERVICES_RESEARCH masking: SINGLE maskingDescription: All study outcomes are extracted from secondary data including electronic health record and healthcare claims databases whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: Care Navigation measure: Rate of patient interest in care navigation measure: Feasibility of patient consent procedures measure: SUD treatment - 30 days measure: SUD treatment - 60 days measure: SUD treatment - 90 days measure: SUD treatment visits - 30 days measure: SUD treatment visits - 60 days measure: SUD treatment visits - 90 days measure: Days until SUD treatment utilization from clinical assessment appointment sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06317974 id: 2022/210 briefTitle: The Effect of Breastfeeding Education on Breast Milk Perception and Self-Efficacy in the Pregnancy Health Belief Model overallStatus: COMPLETED date: 2022-06-30 date: 2022-12-31 date: 2023-02-15 date: 2024-03-19 date: 2024-03-19 name: Istanbul University - Cerrahpasa (IUC) class: OTHER briefSummary: Objective: The aim of this study was to evaluate the effect of breastfeeding education based on the Health Belief Model during the antenatal period on couples' perception and self-efficacy regarding breast milk. conditions: Breastfeeding Education studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized controlled, experimental research design in pre-test, post-test design Made with primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 220 type: ACTUAL name: Breastfeeding education based on the Health Belief model measure: Mothers' and fathers' perception of breast milk, assessed using the Adults' Breast Milk Perception Scale. measure: Breastfeeding self-efficacy of mothers evaluated using the Breastfeeding Self-Efficacy Scale-Short Form during Pregnancy measure: Paternal breastfeeding self-efficacy assessed using the Paternal Breastfeeding Self-Efficacy Scale. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Istanbul University - Cerrahpasa city: Istanbul country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06317961 id: INT200-22 briefTitle: Pilot Study on the Use of iENTER, iCONSENT and iPARTICIPATE E-tools overallStatus: RECRUITING date: 2023-04-05 date: 2025-01-31 date: 2025-01-31 date: 2024-03-19 date: 2024-03-19 name: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano class: OTHER name: Vall d'Hebron Institute of Oncology name: The Netherlands Cancer Institute briefSummary: Precision oncology is the future of fighting cancer. Cancer Core Europe (CCE) developed a precision medicine trial, i.e. the Basket of Basket (BoB) study, to provide personalised treatment to a large number of patients by incorporating a molecular profiling platform. The EU-funded CCE_DART project, developed within the CCE Consortium, is aimed at improving efficiency and transform platform trials into data-rich translational research programmes. Within the CCE_DART project working area D "Patient involvement through information and partnership" three interconnected web e-tools were developed aimed at promoting patient information, recruitment, and involvement as well as facilitating adherence to the CCE BoB trial: 1) iENTER: informative web site addressed to potential BoB trial participants, their caregivers, patients' advocates, and the public; 2) iCONSENT: web app for remote management of the informed consent process in the CCE BoB trial.3) iPARTICIPATE: web app allowing remote access to BoB trial patients trial visits calendar, medications list and posology, to upload documents and download reports, messaging between patients and clinical staff. The main objective of this study is to carry out field testing and assess usability of the e-tools iENTER, iCONSENT and iPARTICIPATE. The study is also addressed at collecting patients' suggestions for improvements of the e-tools. conditions: Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30 type: ESTIMATED measure: SUS questionnaire sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fondazione IRCCS Istituto Nazionale dei Tumori status: RECRUITING city: Milano zip: 20133 country: Italy name: Rosalba Miceli, PhD role: CONTACT phone: +39 0223903198 email: rosalba.miceli@istitutotumori.mi.it name: Sara Iadecola role: CONTACT phone: +39 0223903198 email: sara.iadecola@istitutotumori.mi.it lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06317948 id: IG23150 briefTitle: Improving the Quality of Radiotherapy by Multi-Institution Knowledge-Based Planning Optimization Models (Acronym: MIKAPOCo, Multi-Institutional Knowledge-based Approach in Plan Optimization for the Community) acronym: MIKAPOCo overallStatus: ENROLLING_BY_INVITATION date: 2022-10-28 date: 2022-10-28 date: 2025-10-28 date: 2024-03-19 date: 2024-03-20 name: IRCCS Ospedale San Raffaele class: OTHER briefSummary: Investigators central hypothesis is that it is possible to create libraries of "consistent" Knowledge-Based plan-models derived from large Institutional experiences. These libraries can be used to guide automated RT planning and serve as tools to assist centers for plan quality assurance (QA) and plan prediction.
Quantifying Inter-institute variability of RT planning and building libraries of interchangeable and validated multi-Institutional KB plan prediction models is expected to impact on the quality of planning at the national level. The project has the potential of facilitating the introduction of AI approaches in plan optimization, thus reducing intra and inter-Institute planning variability. Improving plan quality is expected to translate into better outcome after RT in terms of local control and, even more, of side effects and Quality of life. Positive impact is also expected in patient selection for advanced techniques, in plan audit and plan optimization in clinical trials, in technology comparison and cost-benefit analyses as well as in the RT educational field. conditions: Breast Cancer conditions: Prostate Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 1000 type: ESTIMATED name: treatment plan comparison measure: model interchangeability sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS Ospedale San Raffaele city: Milano zip: 20133 country: Italy lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06317935 id: HU-ERG-BK-01 briefTitle: The Effect of Virtual Reality Application on Independence and Hand Functions in Daily Life in Children With CP overallStatus: NOT_YET_RECRUITING date: 2024-04-23 date: 2024-06-29 date: 2024-10-29 date: 2024-03-19 date: 2024-03-19 name: Hacettepe University class: OTHER name: Ankara Bilkent City Hospital briefSummary: The aim of this study is to evaluate the effect of virtual reality applications on the level of independence and upper extremity functionality perceived by children in daily life in children with hemipegic cerebral palsy.
After the initial evaluation is completed, group A, represented as the intervention group, will receive ArmeoSenso virtual reality intervention in the upper extremity hand function laboratory for 3 weeks, 5 days a week, each session for 30 minutes, in addition to traditional occupational therapy and physiotherapy rehabilitation programs. Meanwhile, group B, represented as the control group, will continue the traditional occupational therapy and physiotherapy rehabilitation program. At the end of the third week of the intervention, tests measuring upper extremity functionality and perceived independence level will be repeated.
The control group (B) will receive only traditional occupational therapy and physiotherapy approaches for the first 3 weeks, and between 3-6 weeks, they will receive virtual reality application in addition to traditional approaches for 30 minutes, 5 days a week for 3 weeks. primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 52 type: ESTIMATED name: ArmeoSenso name: Traditional Rehabilitation measure: The effect of virtual reality applications on perceived independence in daily life in hemiplegic CP. measure: The effect of virtual reality applications on upper extremity functionality in daily life in children with hemiplegic CP. measure: Dosimetry of virtual reality applications sex: ALL minimumAge: 6 Years maximumAge: 12 Years stdAges: CHILD facility: Ankara Bilkent City Hospital city: Multiple Locations state: Ankara zip: 06000 country: Turkey name: Başak Karadağ, MSc role: CONTACT phone: +905059462128 email: basakhacettepe@hotmail.com name: Berke Aras, Ass. Prof. role: CONTACT phone: +90365851518 email: drberkearas@gmail.com hasResults: False
nctId: NCT06317922 id: DRYEYE-IVT Project briefTitle: Evaluation of Dry Eye Disease's Signs in Patients Who Were Administered Intravitreal Anti-VEGF Injections acronym: DRYEYE-IVT overallStatus: RECRUITING date: 2024-02-05 date: 2025-05-12 date: 2025-05-12 date: 2024-03-19 date: 2024-03-20 name: Francesco Bandello class: OTHER briefSummary: The goal of this interventional, monocentric, prospective, single-masked, case-control study is to evaluate the efficacy of Thealoz Duo (artificial tear containing trehalose 3 g and hyaluronic acid 0.15 g) in comparison to a saline solution (Hydrabak containing Sodium Chloride 0,9 g, Sodium Dihydrogen Phosphate Dihydrate, Disodium Hydrogen Phosphate Dodecahydrate), to reduce the signs of ocular discomfort and ocular side effects in patients who have received Intravitreal injections.
In any case, the instillation of saline solution should not alter the ocular surface. conditions: Dry Eye Syndromes studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The participants will be randomized in two arms (treatment arm and control arm) in a ratio of 1:1. primaryPurpose: TREATMENT masking: TRIPLE maskingDescription: There are two teams:
* to perform the follow-up visit and assessments provided to test the ocular surface. whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Thealoz Duo; name: sham (Hydrabak) measure: Administration of Ocular Surface Disease Index (OSDI) to the patient measure: administration of Visual Analog Scale for Pain to the patient measure: evaluation of matrix metalloproteinase 9 gene expression measure: TearLab Osmolarity measure: Schirmer's test measure: tear film Break Up Time (tBUT) measure: conjunctival hyperemia according to Efron grading scale measure: fluorescein staining sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS Ospedale San Raffaele _O.U. Ophthalmology status: RECRUITING city: Milan zip: 20123 country: Italy name: Giulia Basile, MPharm role: CONTACT phone: +39 0226433545 email: basile.giulia@hsr.it lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06317909 id: 23-03 DONNER-2 briefTitle: Development of a Novel Non-invasive Inflammometry Following Allergen Challenge in Patients With Mild Allergic Asthma overallStatus: RECRUITING date: 2024-06-01 date: 2025-09 date: 2025-09 date: 2024-03-19 date: 2024-03-19 name: Fraunhofer-Institute of Toxicology and Experimental Medicine class: OTHER briefSummary: The goal of this exploratory method-development study is to to establish and evaluate novel non-invasive methods to monitor airway inflammation induced by allergen challenge (both by instillation during bronchoscopy and by inhalation) in patients with mild allergic asthma.
* blood sampling (in total approx. 190 ml) conditions: Mild Allergic Asthma studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 15 type: ESTIMATED name: allergen challenge measure: Exploratory (1. priority) Changes in soluble mediators [i.e. IL-4, IL-5, IL-8, IL-13, IL-33, TSLP, IL-1, IL-6, INF-alpha, MMP-9, CXCL1, SP-D, albumin] in Bronchoalveolar lavage (BAL) after segmental allergen challenge measure: Exploratory (1. priority) Changes in soluble mediators [i.e. IL-4, IL-5, IL-8, IL-13, IL-33, TSLP, IL-1, IL-6, NF-alpha, MMP-9, CXCL1, SP-D, albumin] in Sputum after inhalative allergen challenge measure: Exploratory (1. priority) Changes in non-invasive exhaled particles [i.e.IL-4, IL-5, IL-8, IL-13, IL-33, TSLP, IL-1, IL-6, NF-alpha, MMP-9, CXCL1, SP-D, albumin]after inhalative allergen challenge measure: Exploratory (1. priority) Changes in non-invasive exhaled particles [i.e.IL-4, IL-5, IL-8, IL-13, IL-33, TSLP, IL-1, IL-6, NF-alpha, MMP-9, CXCL1, SP-D, albumin]after segmental allergen challenge measure: Exploratory (1. priority) Changes in cell analyzation in BAL [i.e.total cells, neutrophil granulocytes, eosinophil granulocytes, basophil granulocytes, monocytes/macrophages, lymphocytes and dendritic cells] after segmental allergen challenge measure: Exploratory (1. priority) Changes in cell analyzation in Sputum [i.e.total cells, neutrophil granulocytes, eosinophil granulocytes, basophil granulocytes, monocytes/macrophages, lymphocytes and dendritic cells] after inhalative allergen challenge measure: Exploratory (2. priority) Detection of Ribonucleic acid (RNA) in exhaled particles measure: Exploratory (2. priority) Changes in Fractional exhaled nitric oxide (FeNO) after inhalative allergen challenge measure: Exploratory (2. priority) Changes in FeNO after segmental allergen challenge measure: Exploratory (2. priority) Quantification of regional ventilation, perfusion, and diffusion by magnetic resonance imaging (MRI) sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fraunhofer Institute for Toxicology and Experimental Medicine status: RECRUITING city: Hannover state: Lower Saxony zip: 30625 country: Germany name: Jens M Hohlfeld role: CONTACT email: jens.hohlfeld@item.fraunhofer.de lat: 52.37052 lon: 9.73322 hasResults: False
nctId: NCT06317896 id: 2024-KY-048-01 briefTitle: Value of Dynamic Monitoring of Early Recurrence of Hepatocellular Carcinoma After Radical Resection Based on CTCS overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-12-31 date: 2026-12-31 date: 2024-03-19 date: 2024-03-19 name: Zhujiang Hospital class: OTHER briefSummary: On the basis of previous retrospective studies, the Task Force will further optimize the CTCs longitudinal surveillance model and initially validate the subclonal origin (CTC-DNA) of recurrent/metastatic foci derived from CTCs at the molecular level in hepatocellular carcinoma, prospective clinical trials will be conducted to further validate the predictive value of the CTCS longitudinal monitoring model in predicting postoperative recurrence of hepatocellular carcinoma, and to verify whether it is earlier than imaging to indicate recurrence, to explore the clinical feasibility of CTCs in guiding postoperative adjuvant therapy of liver cancer, and to provide new ideas for early intervention strategy of liver cancer after operation, to establish a set of standardized clinical scheme of auxiliary treatment for patients with liver cancer after operation for accurate and individualized"Early diagnosis and treatment". conditions: Hepatocellular Carcinoma conditions: Circulating Tumor Cell conditions: Recurrence conditions: Surgery studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 82 type: ESTIMATED name: circulating tumor cells measure: 2-year recurrence-free survival rate measure: Correlation between CTCs status dynamic changes and relapse measure: Correlation between metastasis，primary tumor and CTCs in blood through NGS and CTC-DNA sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Sixth Affiliated Hospital of South China University of Technology city: Foshan state: Guangdong country: China name: Weichao Liang, Prof. role: CONTACT phone: 13590542927 name: Weichao Liang role: PRINCIPAL_INVESTIGATOR lat: 23.02677 lon: 113.13148 facility: Zhujiang Hospital of Southern Medical University city: Guangzhou state: Guangdong zip: 510220 country: China name: Mingxin Pan, Prof. role: CONTACT phone: +8618928918216 email: pmxwxy@sohu.com name: Zhoubin Feng role: CONTACT phone: 19830551997 email: Fzbin1001@163.com name: Mingxin Pan, Prof. role: PRINCIPAL_INVESTIGATOR lat: 23.11667 lon: 113.25 facility: Affiliated Cancer Hospital and Institute of Guangzhou Medical University city: Guangzhou state: Guangdong country: China name: Yinbing Wu, Prof. role: CONTACT phone: 18620007296 name: Yinbing Wu role: PRINCIPAL_INVESTIGATOR lat: 23.11667 lon: 113.25 hasResults: False
nctId: NCT06317883 id: CORALS briefTitle: Childhood Obesity Risk Assessment Longitudinal Study acronym: CORALS overallStatus: ACTIVE_NOT_RECRUITING date: 2019-05-27 date: 2032-07-14 date: 2032-07-14 date: 2024-03-19 date: 2024-03-19 name: Consorcio Centro de Investigación Biomédica en Red (CIBER) class: OTHER_GOV name: Instituto de Salud Carlos III name: Maimónides Biomedical Research Institute of Córdoba name: Universidad de Córdoba name: Institut Investigacio Sanitaria Pere Virgili name: University Rovira i Virgili name: Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN) briefSummary: Childhood obesity is a major public health problem worldwide. Europe has a high prevalence of obesity, which is accentuated in Mediterranean countries. Spain has a high prevalence of both overweight (percentage: 21.5 in boys and 22.2 in girls) and obesity (percentage: 10.6 in boys and 11.8 in girls) in children aged 6-9 years.
From childhood, obesity is associated with an increased risk of diseases such as insulin resistance, type 2 diabetes, hypertension, metabolic syndrome, musculoskeletal problems, sleep disorders and mental health problems. Obesity is a complex, multi-causal problem involving individual risk factors such as behavior and genetics. Behavioral factors include diet, physical activity, sedentary lifestyle, sleep, and others. It is therefore important to study each of the individual risk factors for obesity. There are few large sample studies in European/Spanish children and no longitudinal studies estimating the incidence of obesity in preschool children based on exposure to different risk factors, considering not only the effect of food consumption but also dietary habits and patterns.
nctId: NCT06317870 id: CHUV_PENGIT briefTitle: Pericapsular Nerve Block Versus Intrathecal Morphine for Analgesia After Primary Hip Arthroplasty acronym: PENGIT overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-01-01 date: 2027-05-01 date: 2024-03-19 date: 2024-03-19 name: Centre Hospitalier Universitaire Vaudois class: OTHER briefSummary: The aim of this clinical trial is to compare the analgesic effect of pericapsular nerve block (PENG) with intrathecal morphine in patients scheduled for total hip replacement surgery. The main question to be answered is whether the PENG block is equivalent to intrathecal morphine in reducing postoperative pain.