The MarkVCID Consortium includes 17 US medical centers, a Coordinating Center, an External Advisory Committee, and NIH leadership. Data and biospecimens collected as part of this research study will be stored in a research database and biorepositories, so that researchers can use this information to study brain function. conditions: Cognitive Impairment conditions: Dementia studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 1800 type: ESTIMATED name: No interventions measure: SVD progression as measured by decline in global cognition measure: SVD progression as measured by decline in executive function sex: ALL minimumAge: 60 Years maximumAge: 90 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Southern California status: RECRUITING city: Los Angeles state: California zip: 90033 country: United States name: Danny JJ Wang, PhD, MSCE role: CONTACT phone: 323-442-7246 email: JJ.Wang@loni.usc.edu lat: 34.05223 lon: -118.24368 facility: University of California Los Angeles status: RECRUITING city: Los Angeles state: California zip: 90095 country: United States name: Jason Hinman, MD, PhD role: CONTACT phone: 310-794-1195 email: JHinman@mednet.ucla.edu lat: 34.05223 lon: -118.24368 facility: University of California Davis status: RECRUITING city: Sacramento state: California zip: 95817 country: United States name: Pauline Maillard, PhD role: CONTACT phone: 916-734-3588 email: pmaillard@ucdavis.edu lat: 38.58157 lon: -121.4944 facility: University of California San Francisco status: RECRUITING city: San Francisco state: California zip: 94158 country: United States name: Joel Kramer, PsyD role: CONTACT phone: 415-476-5572 email: Joel.Kramer@ucsf.edu lat: 37.77493 lon: -122.41942 facility: Olive View - UCLA Medical Center status: RECRUITING city: Sylmar state: California zip: 91342 country: United States name: Keith Vossel, MD role: CONTACT phone: 310-794-1195 email: KVossel@mednet.ucla.edu lat: 34.30778 lon: -118.44925 facility: Mayo Clinic Florida status: RECRUITING city: Jacksonville state: Florida zip: 32224 country: United States name: Gregory Day role: CONTACT phone: 904-953-0856 email: Day.Gregory@mayo.edu lat: 30.33218 lon: -81.65565 facility: Rush University Medical Center & Illinois Institute of Technology status: RECRUITING city: Chicago state: Illinois zip: 60612 country: United States name: Konstantinos Arfanakis, PhD role: CONTACT phone: 312-567-3864 email: Konstantinos_Arfanakis@rush.edu lat: 41.85003 lon: -87.65005 facility: University of Kentucky status: RECRUITING city: Lexington state: Kentucky zip: 40536 country: United States name: Gregory Jicha, MD, PhD role: CONTACT phone: 859-257-1000 email: gregory.jicha@uky.edu lat: 37.98869 lon: -84.47772 facility: University of Maryland, Baltimore status: RECRUITING city: Baltimore state: Maryland zip: 21201 country: United States name: Peiying Liu, PhD role: CONTACT phone: 410-706-2441 email: PeiyingLiu@som.umaryland.edu lat: 39.29038 lon: -76.61219 facility: Johns Hopkins University status: RECRUITING city: Baltimore state: Maryland zip: 21287 country: United States name: Hanzhang Lu, PhD role: CONTACT phone: 410-955-1431 email: hlu3@jhmi.edu lat: 39.29038 lon: -76.61219 facility: Mayo Clinic Rochester status: RECRUITING city: Rochester state: Minnesota zip: 55901 country: United States name: Ronald Petersen, MD, PhD role: CONTACT phone: 507-284-1588 email: peter8@mayo.edu lat: 44.02163 lon: -92.4699 facility: University of Mississippi Medical Center status: RECRUITING city: Jackson state: Mississippi zip: 39216 country: United States name: Gwen Windham, MD role: CONTACT phone: 601-984-5610 email: gwindham@umc.edu lat: 32.29876 lon: -90.18481 facility: Washington University in St. Louis status: RECRUITING city: Saint Louis state: Missouri zip: 63110 country: United States name: Jin-Moo Lee, MD, PhD role: CONTACT phone: 314-362-7382 email: leejm@wustl.edu lat: 38.62727 lon: -90.19789 facility: University of New Mexico status: RECRUITING city: Albuquerque state: New Mexico zip: 87131 country: United States name: Gary Rosenberg, MD role: CONTACT phone: 505-272-3315 email: GRosenberg@salud.unm.edu lat: 35.08449 lon: -106.65114 facility: University of Texas Southwestern status: RECRUITING city: Dallas state: Texas zip: 75390 country: United States name: Rong Zhang, PhD role: CONTACT phone: 214-345-4619 email: RongZhang@texashealth.org lat: 32.78306 lon: -96.80667 facility: University of Texas Health Science Center Houston status: RECRUITING city: Houston state: Texas zip: 77030 country: United States name: Sean Savitz, MD role: CONTACT phone: 713-500-7083 email: Sean.I.Savitz@uth.tmc.edu lat: 29.76328 lon: -95.36327 facility: University of Texas Health Science Center San Antonio status: RECRUITING city: San Antonio state: Texas zip: 78229 country: United States name: Claudia Satizabal, PhD role: CONTACT phone: 210-450-8417 email: satizabal@uthscsa.edu lat: 29.42412 lon: -98.49363 hasResults: False