hackint0sh/New-Dataset huggingface dataset:
* Can the device compare pressure dynamics between pre- and post-operative periods in neonates and infants who undergo surgical treatments Participants will undergo standard of care evaluations for hydrocephalus (anterior fontanelle assessment and head circumference measurement) and wear the device during standard of care evaluation; pre- and post- ventricular reservoir taps, as applicable; and/or pre- and post-operatively, as applicable. conditions: Hydrocephalus in Infants studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: Aim 1: Comparison of neonates and infants with hydrocephalus and without Aim 2: Using smart soft contact lens (SSCL) for pre- and post-operative measurements on neonates and/or infants managed operatively (shunt placement) Aim 3: Direct validation by comparing SSCL to external ventricular drain (EVD) intracranial pressure (ICP) monitoring Aim 4: Using SSCL for pre- and post- reservoir tap measurements on neonates and/or infants managed operatively (reservoir placement) Aim 1: 10 patients per arm, two arms Aim 2: 5-10 patients, one arm Aim 3: 5-10 patients, one arm Aim 4: 5-10 patients, one arm primaryPurpose: SCREENING masking: NONE count: 25 type: ESTIMATED name: Non-Invasive Pressure Monitor measure: Efficacy of modified smart soft contact lens evaluation of external intracranial pressure sex: ALL minimumAge: 0 Months maximumAge: 12 Months stdAges: CHILD facility: Riley Hospital for Children city: Indianapolis state: Indiana zip: 46202 country: United States name: Jignesh Talior, MD role: CONTACT phone: 317-944-6201 lat: 39.76838 lon: -86.15804 hasResults: False
nctId: NCT06310200 id: IRB-2023-398 briefTitle: Sphenopalatine Ganglion Block and Cold Induced Headaches overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-06-01 date: 2024-07-01 date: 2024-03-15 date: 2024-03-15 name: Wright State University class: OTHER briefSummary: The primary objective of this study is to determine if a sphenopalatine ganglion (SPG) block, performed through intranasal atomization of 4% lidocaine, is able to prevent cold induced cephalgia ("Brain Freeze"). Secondary objectives will be to determine the degree of decreased pain/duration of brain freeze after sphenopalatine ganglion block conditions: Cold Induced Headache conditions: Brain Freeze conditions: Cold Induced Cephalgia conditions: Headache studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: QUADRUPLE maskingDescription: All besides PI whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 30 type: ESTIMATED name: Lidocaine Topical 4% Topical Solution name: Bitrex name: normal saline measure: Does sphenopalatine ganglion (SPG) block prevent cold induced cephalgia measure: Degree of pain measure: Duration of brain freeze measure: Time to onset of headache sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06310174 id: IRB00362883 briefTitle: Study Examining the Effect of a Novel Cannulation Knife on User Satisfaction and Common Central Venous Catheter Insertion Complications acronym: SCAD overallStatus: RECRUITING date: 2023-12-22 date: 2026-03 date: 2027-05 date: 2024-03-15 date: 2024-03-15 name: Johns Hopkins University class: OTHER briefSummary: The purpose of this study is to assess user satisfaction and the frequency of common central venous catheter insertion complications when using a novel cannulation knife. conditions: Central Venous Catheter Exit Site Infection studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 144 type: ESTIMATED measure: User satisfaction with the new cannulation knife for CVC insertion. measure: Frequency of skin incision revisions. measure: Frequency of procedures being aborted and restarted. measure: Frequency of reverting to use of the scalpel normally used to make the incision. measure: Presence of a clean, dry dressing. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Johns Hopkins Hospital status: RECRUITING city: Baltimore state: Maryland zip: 21287 country: United States name: Lisa Fornaresio, PhD role: CONTACT phone: 443-927-3984 email: lisa.fornaresio@jhmi.edu name: Zyriah Robinson role: CONTACT phone: 443.927.3983 email: zyriah.robinson@jhmi.edu name: James Gammie, MD role: PRINCIPAL_INVESTIGATOR lat: 39.29038 lon: -76.61219 hasResults: False
nctId: NCT06310161 id: 855161 briefTitle: Light Therapy in End Stage Kidney Disease overallStatus: NOT_YET_RECRUITING date: 2024-08-01 date: 2024-12-01 date: 2025-03-01 date: 2024-03-15 date: 2024-04-23 name: University of Pennsylvania class: OTHER briefSummary: The goal of this clinical trial is to test light therapy in patients with end stage kidney disease who are receiving hemodialysis. The main aim is to determine if light therapy decreases fatigue severity. Participants will receive light therapy using special glasses for one hour during the dialysis sessions for four weeks of treatment. conditions: End Stage Renal Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Bright light name: Dim Light measure: Fatigue Severity Scale sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06310148 id: UW 24-019 briefTitle: Evaluation of the Chronic Disease Co-Care Pilot Scheme overallStatus: RECRUITING date: 2024-01-18 date: 2025-07-01 date: 2026-12-31 date: 2024-03-15 date: 2024-03-22 name: The University of Hong Kong class: OTHER name: Health and Medical Research Fund name: Primary Healthcare Office, Hong Kong briefSummary: The Chronic Disease Co-Care (CDCC) Pilot Scheme is initiated for early screening and management of people with hypertension (HT), pre-diabetes mellitus (pre-DM) and diabetes mellitus (DM) in Hong Kong. This study will evaluate the quality of care, feasibility, acceptability, effectiveness and cost-effectiveness of the Scheme.
This is a 12-month cohort study among the District Health Centre (DHC) or DHC Express, healthcare providers, CDCC participants and a comparison group of 1,886 non-participants. All the person-in charge, 2 family doctors and 1 of each allied health provider from each DHC/DHC Express will be administered with the questionnaires on quality of care and costing. All CDCC participants will be included in subject characteristics, among which a convenience sample of 548 will complete a telephone survey on experience, enablement and satisfaction of the CDCC Pilot Scheme. The health outcomes of 1,886 CDCC participants and 1,886 non-participants will be compared for evaluation of effectiveness and cost-effectiveness.
Participant characteristics, enablement, compliance to the standards of care, and costing of CDCC Pilot Scheme will be summarized using descriptive statistics. Differences in the proportion of patients meeting treatment targeted for HT, pre-DM and DM after 12 months will be compared by chi-squared test and logistic regressions. The incremental cost-effectiveness ratio will be evaluated by comparing with the World Health Organization (WHO) threshold. This study will inform future healthcare planning and policy for manpower and resource allocation. conditions: Diabetes Mellitus, Type 2 conditions: Hypertension conditions: Chronic Disease conditions: Disease Management conditions: Primary Healthcare studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 3772 type: ESTIMATED name: The Chronic Disease Co-Care (CDCC) Pilot Scheme measure: Characteristics of the Chronic Disease Co-Care (CDCC) participants measure: Healthcare providers' adherence to care standards on the evaluation framework by the quality of care questionnaire measure: Enablement of CDCC participants by the Chinese Patient Enablement Instrument measure: Effectiveness of the CDCC Pilot Scheme on disease control for pre-diabetes mellitus (pre-DM) and DM in percent of Glycated Hemoglobin (HbA1c) and hypertension (HT) in millimeter of mercury of systolic blood pressure (SBP)/diastolic blood pressure (DBP) measure: The additional costs for delivering the CDCC Pilot Scheme by the costing questionnaire measure: The cost-effectiveness for delivering the CDCC Pilot Scheme on the incremental cost-effectiveness ratio measure: Experience and satisfaction of CDCC participants by the experience and enablement questionnaire measure: Number of attendance to doctor consultation on times in comparison groups measure: Rate of diagnosis of HT and/or DM on dichotomous yes/no response in comparison groups measure: Changes in mean HbA1c/FPG in percent between two groups measure: Changes in mean SBP and DBP in millimeter of mercury between two groups measure: Changes in mean of HbA1c in percent between two groups measure: Changes in BMI in kilogram per square metre between two groups measure: Changes in the rate of smoking cessation and rate of alcohol abstinence between two groups by the Health Risk Factor Assessment measure: The predicted 10-year cardiovascular disease (CVD) risk between two groups measure: Amount of direct medical costs between two groups sex: ALL minimumAge: 45 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Jockey Club Building for Interdisciplinary Research 5 Sassoon Road, Pok Fu Lam, HONG KONG status: RECRUITING city: Hong Kong country: Hong Kong name: Eric Yuk Fai Wan role: CONTACT phone: 852 28315057 phoneExt: 852 28147475 email: yfwan@hku.hk lat: 22.27832 lon: 114.17469 hasResults: False
nctId: NCT06310135 id: STUDY-23-00816 briefTitle: Filtered Eyewear to Prevent Light-induced Melatonin Suppression - Aim 1 overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-05 date: 2024-03-15 date: 2024-03-15 name: Icahn School of Medicine at Mount Sinai class: OTHER briefSummary: The aim of this study is to determine the relative effectiveness of monocular and binocular light exposures, with and without selective blue-blocking filtering, on nocturnal melatonin suppression, subjective sleepiness, and visual performance of night shift workers. conditions: Sleep Quality studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 30 type: ESTIMATED name: Filtered Eyewear name: Unfiltered Eyewear name: No Filters measure: Melatonin Levels measure: Karolinska Sleepiness scale to measure Subjective Sleepiness measure: Numerical Verification Task (NVT) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Light and Health Research Center city: Menands state: New York zip: 12204 country: United States name: Barbara Plitnick, RN role: CONTACT phone: 518-242-4603 email: barbara.plitnick@mountsinai.org name: Mariana Figueiro role: PRINCIPAL_INVESTIGATOR lat: 42.69202 lon: -73.72456 hasResults: False
nctId: NCT06310122 id: ESWT on planter fascitis briefTitle: Effect of Extracorporeal Shockwave Therapy on Gait Parameters in Patients With Planter Fascitis overallStatus: NOT_YET_RECRUITING date: 2024-03-12 date: 2024-09-01 date: 2025-03-30 date: 2024-03-15 date: 2024-03-15 name: Cairo University class: OTHER briefSummary: The purpose of this study is :
* to determine the effect of extracorporeal shockwave on gait parameters in patients with plantar fasciitis conditions: Plantar Fascitis conditions: Extracorporeal Shockwave Therapy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Two groups : group (A) , group (B) One of them will receive traditional treatment ( ultra sound , exercises) Other one will recieve extracorporeal shockwave therapy and traditional treatment also primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 52 type: ESTIMATED name: Extracorporeal shockwave therapy name: ultrasound measure: Stride length mean distance measured by (meter) measure: stride time mean time measured by (second) measure: speed mean distance/ time measured by (meter/second) measure: cadence mean number of steps /times. measure: pain intensity level. measure: Foot function sex: FEMALE minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT hasResults: False
nctId: NCT06310109 id: 2358_OPBG 2020 briefTitle: Effect of Pediatric Intensive Care Unit Diaries on PICS-p acronym: PICS-p overallStatus: RECRUITING date: 2021-07-14 date: 2024-05-31 date: 2024-10-31 date: 2024-03-15 date: 2024-03-15 name: Bambino Gesù Children's Hospital IRCCS class: OTHER name: Ministry of Health, Italy briefSummary: When children become very sick and need to stay in a Pediatric Intensive Care Unit (PICU), it can have a big impact on their recovery and their family's well-being. Sometimes kids and their families feel worried or sad even after they leave the hospital. This can have an impact on the quality of their life after hospital discharge.
The investigators hope that by understanding how these diaries can help, healthcare professionals can make hospital experiences better for everyone involved. conditions: Post Intensive Care Syndrome conditions: Narrative Medicine conditions: Post Traumatic Stress Disorder conditions: Anxiety conditions: Depression studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 110 type: ESTIMATED name: PICU diary measure: Parent's Post Traumatic Stress Disease (PTSD) measure: Parent's Anxiety measure: Child's Strengths and difficulties measure: Child's Post Traumatic Stress Disease (PTSD) measure: Child's Anxiety measure: Child's Depression measure: Satisfaction with PICU care measure: Patient's Quality of Life sex: ALL maximumAge: 19 Years stdAges: CHILD stdAges: ADULT facility: Bambino Gesù Children's Hospital IRCCS status: RECRUITING city: Rome zip: 00165 country: Italy name: Orsola Gawronski, PhD role: CONTACT lat: 41.89193 lon: 12.51133 hasResults: False
nctId: NCT06310096 id: E-59394181-604.01-79277 briefTitle: Role of Thoracolumbar Fascia Stretching on Pain Parameters With Non-Specific Chronic Low Back Pain overallStatus: RECRUITING date: 2024-01-01 date: 2024-03-11 date: 2024-03-11 date: 2024-03-15 date: 2024-03-15 name: Atılım University class: OTHER name: Kirsehir Ahi Evran Universitesi briefSummary: Role of Thoracolumbar Fascia Stretching on Pain Parameters with Non-Specific Chronic Low Back Pain conditions: Pain conditions: Low Back Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: NONE count: 30 type: ESTIMATED name: TLF fascial stretching exercise name: conventional physiotherapy program. measure: Pain threshold measure: Temporal summation measure: NRS(Numerical rating scales) measure: Pain Sensitivity Scale (PSS) measure: Brief Pain Inventory (BPI) sex: ALL minimumAge: 20 Years maximumAge: 60 Years stdAges: ADULT facility: Atılım University status: RECRUITING city: Ankara country: Turkey name: Naime Uluğ, PhD. role: CONTACT phone: +905365434409 email: naime.ulug@atilim.edu.tr lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06310083 id: SMR for Turbinate Hypertrophy briefTitle: Endoscopic Submucosal Resection Turbinoplasty VS Turbinectomy overallStatus: COMPLETED date: 2023-02-01 date: 2024-01-31 date: 2024-01-31 date: 2024-03-15 date: 2024-03-15 name: Ahmed Nabil Selim class: OTHER briefSummary: The aim of our study is to compare endoscopic submucosal resection Turbinoplasty and partial inferior turbinectomy regarding clinical and radiological evaluation and its possible complications in the treatment of Chronic inferior turbinate hypertrophy. conditions: Turbinate; Hypertrophy Mucous Membrane studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A total of 40 patients were enrolled in the study. The patients were randomly classified into two groups, with 20 in each group.
Group B (control group): Who applied for partial inferior turbinectomy. primaryPurpose: TREATMENT masking: QUADRUPLE maskingDescription: The surgeons performed the nasal surgery and evaluating postoperative measurable outcomes was blinded about cases who were subjected to Endoscopic submucosal resection Turbinoplasty whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 40 type: ACTUAL name: Submucosal Resection Turbinoplasty Versus Partial Inferior Turbinectomy measure: Nasal Obstruction measure: Nasal Discharge measure: Crustations measure: intra operative blood loss measure: Duration of operation (Minutes ) measure: Hyposmia measure: Size Of Anterior part of Turbinate measure: Size Of Posterior part of Turbinate measure: Space of Anterior nasal Cavity measure: Space of posterior nasal Cavity sex: ALL minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Al-Azhar University Hospital of Assiut city: Assiut zip: 17511 country: Egypt lat: 27.18096 lon: 31.18368 hasResults: False
nctId: NCT06310070 id: IRB-23-1965 briefTitle: 3D Printed Personalized Ostomy Appliance acronym: 3DPPOA overallStatus: NOT_YET_RECRUITING date: 2025-03-05 date: 2025-03-05 date: 2025-06-05 date: 2024-03-13 date: 2024-03-21 name: Carilion Clinic class: OTHER name: Virginia Polytechnic Institute and State University briefSummary: The goal of this clinical trial is to learn about the effectiveness of using a 3D scan for a personal ostomy appliance. The main question it aims to answer is:
* Participate in daily surveys and weekly quality of life surveys conducted over the phone conditions: 3D Printing conditions: Ostomy conditions: Leakage studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: PREVENTION masking: NONE count: 30 type: ESTIMATED name: 3D Printed Personalized Ostomy Appliance measure: Incidence of Leaks measure: Number of appliances measure: Overall patient satisfaction sex: ALL minimumAge: 18 Years maximumAge: 100 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06310057 id: 4139 briefTitle: Tofacitinib in the Treatment of Refractory Axial Spondyloarthritis Patients: A Dose Escalation Study overallStatus: COMPLETED date: 2022-01-01 date: 2024-03-01 date: 2024-03-01 date: 2024-03-13 date: 2024-03-13 name: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh class: OTHER name: Incepta Pharmaceuticals Ltd briefSummary: The goal of this clinical trial is to assess the efficacy of tofacitinib in refractory axial spodyloarthritis (ax-SpA) with dose escalation from 10mg to 15mg. Patients will start on 10mg and then divided into 2 groups (10 and 15) at 3rd month according to major improvement criteria.
* If escalation of tofacitinib is justified if clinical criteria is not fulfilled at 10mg conditions: Axial Spondyloarthritis studyType: INTERVENTIONAL phases: PHASE4 allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Dose escalation study, all the patients will recieve 10mg tofacitinib at the beginning. Then at 3rd month, one group will continue at 10mg, if they fulfill the ASDAS major improvement criteria and other group will escalate to 15mg. primaryPurpose: TREATMENT masking: NONE count: 92 type: ACTUAL name: Tofacitinib measure: To assess the ASDAS CRP major improvement criteria in refractory ax-SpA patients with dose escalation from 10mg to 15mg measure: Clinicodemographic characteristics of Ax-SpA, ASDAS CRP outcome rates, quality of life, adverse effects sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Bangabandhu Sheikh Mujib Medical University city: Dhaka zip: 1000 country: Bangladesh lat: 23.7104 lon: 90.40744 hasResults: False
nctId: NCT06310044 id: Commiphora Myrrh briefTitle: Effect of Commiphora Myrrh Solution as a Root Canal Irrigant on Post Operative Pain and Bacterial Load Reduction in Necrotic Tooth overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-01-01 date: 2025-01-01 date: 2024-03-13 date: 2024-03-13 name: Cairo University class: OTHER briefSummary: Clinically compare the post-operative pain , incidences post-operative swelling , post-operative number of analgesic tablets taken by patient and amount of bacterial load reduction after using 50% Commiphora Myrrh Chemomechanical preparation , versus 2.5% NaOCl,in asymptomatic necrotic mandibular premolar treated in single visit. conditions: Necrotic Pulp studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 42 type: ESTIMATED name: Root canal irrigant Commiphora Myrrh 50% measure: Post-operative pain measure: incidence of Post-operative swelling measure: Amount of intracanal Bacterial CFUs/ml measure: Number of analgesic Counting Tablets taken by the patient after endodontic treatment sex: ALL minimumAge: 20 Years maximumAge: 40 Years stdAges: ADULT hasResults: False
nctId: NCT06310018 id: 2023A070902 briefTitle: Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE acronym: SONIC-PE overallStatus: NOT_YET_RECRUITING date: 2024-06-30 date: 2025-06-30 date: 2025-12-31 date: 2024-03-13 date: 2024-03-15 name: Brigham and Women's Hospital class: OTHER name: Boston Scientific Corporation briefSummary: SONIC-PE is a multicenter, prospective, single-arm study of 10 patients with bilateral PE treated with ultrasound-facilitated, catheter-directed lower-dose fibrinolysis (total dose 8 mg tPA given as 2 mg/hour/catheter over 2 hours) followed by 50 patients (total dose 6 mg tPA given as 3 mg/hour/catheter given over 1 hour) with the EKOS+™ system to determine its impact on the change in RV-to-LV diameter, refined Modified Miller Score, and distal pulmonary vascular blood volume as well as to assess International Society on Thrombosis and Haemostasis (ISTH) major bleeding. conditions: Pulmonary Embolism conditions: Right Ventricular Dysfunction conditions: Right Ventricular Failure studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: multicenter, prospective, single-arm study primaryPurpose: TREATMENT masking: NONE count: 60 type: ESTIMATED name: Ultrasound-facilitated, catheter-directed lower-dose fibrinolysis measure: Change in RV-to-LV diameter ratio as measured by chest CT from baseline to 48 ± 6 hours measure: Frequency of ISTH major bleeding at 72 hours measure: Change in chest CT-measured blood volume in the distal pulmonary vasculature from baseline to 48 ± 6 hours measure: Change in refined Modified Miller Score as measured by chest CT from baseline to 48 ± 6 hours as measured by chest CT from baseline to 48 ± 6 hours sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False