Study investigators responsible for analysing cognitive performance variables and physiological sleep data will be be blind to which vibration and noise interventions were introduced on which study nights. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 24 type: ESTIMATED name: Railway noise name: Low level railway vibration name: Intermediate level railway vibration name: High level railway vibration measure: Fasting insulin resistance in the morning immediately after the Control night measure: Fasting insulin resistance in the morning immediately after the low vibration night measure: Fasting insulin resistance in the morning immediately after the intermediate vibration night measure: Fasting insulin resistance in the morning immediately after the high vibration night measure: Total sleep time during the Control night measure: Total sleep time during the low vibration night measure: Total sleep time during the intermediate vibration night measure: Total sleep time during the high vibration night measure: Total amount of N1 sleep during the Control night measure: Total amount of N2 sleep during the Control night measure: Total amount of N3 sleep during the Control night measure: Total amount of rapid eye movement (REM) sleep during the Control night measure: Total amount of N1 sleep during the low vibration night measure: Total amount of N2 sleep during the low vibration night measure: Total amount of N3 sleep during the low vibration night measure: Total amount of rapid eye movement (REM) sleep during the low vibration night measure: Total amount of N1 sleep during the intermediate vibration night measure: Total amount of N2 sleep during the intermediate vibration night measure: Total amount of N3 sleep during the intermediate vibration night measure: Total amount of rapid eye movement (REM) sleep during the intermediate vibration night measure: Total amount of N1 sleep during the high vibration night measure: Total amount of N2 sleep during the high vibration night measure: Total amount of N3 sleep during the high vibration night measure: Total amount of rapid eye movement (REM) sleep during the high vibration night measure: Wakefulness after sleep onset (WASO) during the Control night measure: Wakefulness after sleep onset (WASO) during the low vibration night measure: Wakefulness after sleep onset (WASO) during the intermediate night measure: Wakefulness after sleep onset (WASO) during the high vibration night measure: Number of awakenings during the Control night measure: Number of awakenings during exposure to low vibration measure: Number of awakenings during exposure to intermediate vibration measure: Number of awakenings during exposure to high vibration measure: Sleep onset latency (SOL) during the Control Night measure: Sleep onset latency (SOL) during the low vibration night measure: Sleep onset latency (SOL) during the intermediate vibration night measure: Sleep onset latency (SOL) during the high vibration night measure: Sleep efficiency during the Control night measure: Sleep efficiency during the low vibration night measure: Sleep efficiency during the intermediate vibration night measure: S Sleep efficiency during the high vibration night measure: Sleep depth assessed using the odds ratio product (ORP) during the Control night measure: Sleep depth assessed using the odds ratio product (ORP) during the low vibration night measure: Sleep depth assessed using the odds ratio product (ORP) during the intermediate vibration night measure: Sleep depth assessed using the odds ratio product (ORP) during the high vibration night measure: Maximal change of odds ratio product (ORP) during exposure to railway vibration events measure: Area under the curve of odds ratio product (ORP) during exposure to railway vibration events, calculated using the trapezoid rule measure: N-acetylglucosamine/galactosamine (GlycA) concentration after the Control night measure: N-acetylglucosamine/galactosamine (GlycA) concentration after exposure to low vibration night measure: N-acetylglucosamine/galactosamine (GlycA) concentration after exposure to intermediate vibration measure: N-acetylglucosamine/galactosamine (GlycA) concentration after exposure to high vibration measure: Sialic acid (GlycB) concentration after the Control night measure: Sialic acid (GlycB) concentration after exposure to low vibration measure: Sialic acid (GlycB) concentration after exposure to intermediate vibration measure: Sialic acid (GlycB) concentration after exposure to high vibration measure: Supramolecular phospholipid composite (SPC) concentration after the Control night measure: Supramolecular phospholipid composite (SPC) concentration after exposure to low vibration measure: Supramolecular phospholipid composite (SPC) concentration after exposure to intermediate vibration measure: Supramolecular phospholipid composite (SPC) concentration after exposure to high vibration measure: Ethanol concentration (mmol/L) after the Control night measure: Ethanol concentration (mmol/L) after exposure to low vibration night measure: Ethanol concentration (mmol/L) after exposure to intermediate vibration night measure: Ethanol concentration (mmol/L) after exposure to high vibration night measure: Trimethylamine-N-oxide concentration (mmol/L) after exposure to Control night measure: Trimethylamine-N-oxide concentration (mmol/L) after exposure to low vibration night measure: Trimethylamine-N-oxide concentration (mmol/L) after exposure to intermediate vibration night measure: Trimethylamine-N-oxide concentration (mmol/L) after exposure to high vibration night measure: 2-Aminobutyric acid concentration (mmol/L) after exposure to Control night measure: 2-Aminobutyric acid concentration (mmol/L) after exposure to low vibration night measure: 2-Aminobutyric acid concentration (mmol/L) after exposure to intermediate vibration night measure: 2-Aminobutyric acid concentration (mmol/L) after exposure to high vibration night measure: Alanine concentration (mmol/L) after exposure to Control night measure: Alanine concentration (mmol/L) after exposure to low vibration night measure: Alanine concentration (mmol/L) after exposure to intermediate vibration night measure: Alanine concentration (mmol/L) after exposure to high vibration night measure: Asparagine concentration (mmol/L) after exposure to Control night measure: Asparagine concentration (mmol/L) after exposure to low vibration night measure: Asparagine concentration (mmol/L) after exposure to intermediate vibration night measure: Asparagine concentration (mmol/L) after exposure to high vibration night measure: Creatine concentration (mmol/L) after exposure to Control night measure: Creatine concentration (mmol/L) after exposure to low vibration night measure: Creatine concentration (mmol/L) after exposure to intermediate vibration night measure: Creatine concentration (mmol/L) after exposure to high vibration night measure: Creatinine concentration (mmol/L) after exposure to Control night measure: Creatinine concentration (mmol/L) after exposure to low vibration night measure: Creatinine concentration (mmol/L) after exposure to intermediate vibration night measure: Creatinine concentration (mmol/L) after exposure to high vibration night measure: Glutamic acid concentration (mmol/L) after exposure to Control night measure: Glutamic acid concentration (mmol/L) after exposure to low vibration night measure: Glutamic acid concentration (mmol/L) after exposure to intermediate vibration night measure: Glutamic acid concentration (mmol/L) after exposure to high vibration night measure: Glutamine concentration (mmol/L) after exposure to Control night measure: Glutamine concentration (mmol/L) after exposure to low vibration night measure: Glutamine concentration (mmol/L) after exposure to intermediate vibration night measure: Glutamine concentration (mmol/L) after exposure to high vibration night measure: Glycine concentration (mmol/L) after exposure to Control night measure: Glycine concentration (mmol/L) after exposure to low vibration night measure: Glycine concentration (mmol/L) after exposure to intermediate vibration night measure: Glycine concentration (mmol/L) after exposure to high vibration night measure: Histidine concentration (mmol/L) after exposure to Control night measure: Histidine concentration (mmol/L) after exposure to low vibration night measure: Histidine concentration (mmol/L) after exposure to intermediate vibration night measure: Histidine concentration (mmol/L) after exposure to high vibration night measure: Isoleucine concentration (mmol/L) after exposure to Control night measure: Isoleucine concentration (mmol/L) after exposure to low vibration night measure: Isoleucine concentration (mmol/L) after exposure to intermediate vibration night measure: Isoleucine concentration (mmol/L) after exposure to high vibration night measure: Leucine concentration (mmol/L) after exposure to Control night measure: Leucine concentration (mmol/L) after exposure to low vibration night measure: Leucine concentration (mmol/L) after exposure to intermediate vibration night measure: Leucine concentration (mmol/L) after exposure to high vibration night measure: Lysine concentration (mmol/L) after exposure to Control night measure: Lysine concentration (mmol/L) after exposure to low vibration night measure: Lysine concentration (mmol/L) after exposure to intermediate vibration night measure: Lysine concentration (mmol/L) after exposure to high vibration night measure: Methionine concentration (mmol/L) after exposure to Control night measure: Methionine concentration (mmol/L) after exposure to low vibration night measure: Methionine concentration (mmol/L) after exposure to intermediate vibration night measure: Methionine concentration (mmol/L) after exposure to high vibration night measure: N,N-Dimethylglycine concentration (mmol/L) after Control night measure: N,N-Dimethylglycine concentration (mmol/L) after exposure to low vibration night measure: N,N-Dimethylglycine concentration (mmol/L) after exposure to intermediate vibration night measure: N,N-Dimethylglycine concentration (mmol/L) after exposure to high vibration night measure: Ornithine concentration (mmol/L) after exposure to Control night measure: Ornithine concentration (mmol/L) after exposure to low vibration night measure: Ornithine concentration (mmol/L) after exposure to intermediate vibration night measure: Ornithine concentration (mmol/L) after exposure to high vibration night measure: Phenylalanine concentration (mmol/L) after exposure to Control night measure: Phenylalanine concentration (mmol/L) after exposure to low vibration night measure: Phenylalanine concentration (mmol/L) after exposure to intermediate vibration night measure: Phenylalanine concentration (mmol/L) after exposure to high vibration night measure: Proline concentration (mmol/L) after exposure to Control night measure: Proline concentration (mmol/L) after exposure to low vibration night measure: Proline concentration (mmol/L) after exposure to intermediate vibration night measure: Proline concentration (mmol/L) after exposure to high vibration night measure: Sarcosine concentration (mmol/L) after exposure to Control night measure: Sarcosine concentration (mmol/L) after exposure to low vibration night measure: Sarcosine concentration (mmol/L) after exposure to intermediate vibration night measure: Sarcosine concentration (mmol/L) after exposure to high vibration night measure: Threonine concentration (mmol/L) after exposure to Control night measure: Threonine concentration (mmol/L) after exposure to low vibration night measure: Threonine concentration (mmol/L) after exposure to intermediate vibration night measure: Threonine concentration (mmol/L) after exposure to high vibration night measure: Tyrosine concentration (mmol/L) after exposure toControl night measure: Tyrosine concentration (mmol/L) after exposure to low vibration night measure: Tyrosine concentration (mmol/L) after exposure to intermediate vibration night measure: Tyrosine concentration (mmol/L) after exposure to high vibration night measure: Valine concentration (mmol/L) after Control night measure: Valine concentration (mmol/L) after exposure to low vibration night measure: Valine concentration (mmol/L) after exposure to intermediate vibration night measure: Valine concentration (mmol/L) after exposure to high vibration night measure: 2-Hydroxybutyric acid concentration (mmol/L) after exposure to Control night measure: 2-Hydroxybutyric acid concentration (mmol/L) after exposure to low vibration night measure: 2-Hydroxybutyric acid concentration (mmol/L) after exposure to intermediate vibration night measure: 2-Hydroxybutyric acid concentration (mmol/L) after exposure to high vibration night measure: Acetic acid concentration (mmol/L) after exposure to Control night measure: Acetic acid concentration (mmol/L) after exposure to low vibration night measure: Acetic acid concentration (mmol/L) after exposure to intermediate vibration night measure: Acetic acid concentration (mmol/L) after exposure to high vibration night measure: Citric acid concentration (mmol/L) after Control night measure: Citric acid concentration (mmol/L) after exposure to low vibration night measure: Citric acid concentration (mmol/L) after exposure to intermediate vibration night measure: Citric acid concentration (mmol/L) after exposure to high vibration night measure: Formic acid concentration (mmol/L) after exposure to Control night measure: Formic acid concentration (mmol/L) after exposure to low vibration night measure: Formic acid concentration (mmol/L) after exposure to intermediate vibration night measure: Formic acid concentration (mmol/L) after exposure to high vibration night measure: Lactic acid concentration (mmol/L) after exposure to Control night measure: Lactic acid concentration (mmol/L) after exposure to low vibration night measure: Lactic acid concentration (mmol/L) after exposure to intermediate vibration night measure: Lactic acid concentration (mmol/L) after exposure to high vibration night measure: Succinic acid concentration (mmol/L) after exposure to Control night measure: Succinic acid concentration (mmol/L) after exposure to low vibration night measure: Succinic acid concentration (mmol/L) after exposure to intermediate vibration night measure: Succinic acid concentration (mmol/L) after exposure to high vibration night measure: Choline concentration (mmol/L) after exposure to Control night measure: Choline concentration (mmol/L) after exposure to low vibration night measure: Choline concentration (mmol/L) after exposure to intermediate vibration night measure: Choline concentration (mmol/L) after exposure to high vibration night measure: 2-Oxoglutaric acid concentration (mmol/L) after exposure to Control night measure: 2-Oxoglutaric acid concentration (mmol/L) after exposure to low vibration night measure: 2-Oxoglutaric acid concentration (mmol/L) after exposure to intermediate vibration night measure: 2-Oxoglutaric acid concentration (mmol/L) after exposure to high vibration night measure: 3-Hydroxybutyric acid concentration (mmol/L) after exposure to Control night measure: 3-Hydroxybutyric acid concentration (mmol/L) after exposure to low vibration night measure: 3-Hydroxybutyric acid concentration (mmol/L) after exposure to intermediate vibration night measure: 3-Hydroxybutyric acid concentration (mmol/L) after exposure to high vibration night measure: Acetoacetic acid concentration (mmol/L) after exposure to Control night measure: Acetoacetic acid concentration (mmol/L) after exposure to low vibration night measure: Acetoacetic acid concentration (mmol/L) after exposure to intermediate vibration night measure: Acetoacetic acid concentration (mmol/L) after exposure to high vibration night measure: Acetone concentration (mmol/L) after exposure to Control night measure: Acetone concentration (mmol/L) after exposure to low vibration night measure: Acetone concentration (mmol/L) after exposure to intermediate vibration night measure: Acetone concentration (mmol/L) after exposure to high vibration night measure: Pyruvic acid concentration (mmol/L) after exposure to Control night measure: Pyruvic acid concentration (mmol/L) after exposure to low vibration night measure: Pyruvic acid concentration (mmol/L) after exposure to intermediate vibration night measure: Pyruvic acid concentration (mmol/L) after exposure to high vibration night measure: D-Galactose concentration (mmol/L) after exposure to Control night measure: D-Galactose concentration (mmol/L) after exposure to low vibration night measure: D-Galactose concentration (mmol/L) after exposure to intermediate vibration night measure: D-Galactose concentration (mmol/L) after exposure to high vibration night measure: Glucose concentration (mmol/L) after exposure to Control night measure: Glucose concentration (mmol/L) after exposure to low vibration night measure: Glucose concentration (mmol/L) after exposure to intermediate vibration night measure: Glucose concentration (mmol/L) after exposure to high vibration night measure: Glycerol concentration (mmol/L) after exposure to Control night measure: Glycerol concentration (mmol/L) after exposure to low vibration night measure: Glycerol concentration (mmol/L) after exposure to intermediate vibration night measure: Glycerol concentration (mmol/L) after exposure to high vibration night measure: Dimethylsulfone concentration (mmol/L) after exposure to Control night measure: Dimethylsulfone concentration (mmol/L) after exposure to low vibration night measure: Dimethylsulfone concentration (mmol/L) after exposure to intermediate vibration night measure: Dimethylsulfone concentration (mmol/L) after exposure to high vibration night measure: Response to an oral glucose bolus, calculated as area under curve for glucose, in the morning after the control night measure: Response to an oral glucose bolus, calculated as area under curve for glucose, in the morning after the low vibration night measure: Response to an oral glucose bolus, calculated as area under curve for glucose, in the morning after the intermediate vibration night measure: Response to an oral glucose bolus, calculated as area under curve for glucose, in the morning after the high vibration night measure: Response to an oral glucose load calculated as area under curve for insulin, in the morning after the low vibration night measure: Response to an oral glucose load calculated as area under curve for insulin, in the morning after the intermediate vibration night measure: Response to an oral glucose load calculated as area under curve for insulin, in the morning after the high vibration night measure: Early response to an oral glucose load calculated as area under curve for insulin, in the morning after the control night measure: Early response to an oral glucose load calculated as area under curve for insulin, in the morning after the low vibration night measure: Early response to an oral glucose load calculated as area under curve for insulin, in the morning after the intermediate vibration night measure: Early response to an oral glucose load calculated as area under curve for insulin, in the morning after the high vibration night measure: Glucose tolerance in the morning after exposure to low vibration, assessed as glucose concentration 120 minutes after a glucose bolus measure: Glucose tolerance in the morning after exposure to intermediate vibration, assessed as glucose concentration 120 minutes after a glucose bolus measure: Glucose tolerance in the morning after exposure to high vibration, assessed as glucose concentration 120 minutes after a glucose bolus measure: Glucose tolerance in the morning after Control night, assessed as glucose concentration 120 minutes after a glucose bolus measure: Stumvoll Insulin sensitivity Index in the morning after control measure: Stumvoll Insulin sensitivity Index in the morning after exposure to low vibration measure: Stumvoll Insulin sensitivity Index in the morning after exposure to intermediate vibration measure: Stumvoll Insulin sensitivity Index in the morning after exposure to high vibration measure: Matsuda insulin sensitivity index in the morning after control exposure measure: Matsuda insulin sensitivity index in the morning after exposure to low vibration measure: Matsuda insulin sensitivity index in the morning after exposure to intermediate vibration measure: Matsuda insulin sensitivity index in the morning after exposure to high vibration measure: Evening subjective sleepiness, assessed using the Karolinska Sleepiness Scale after exposure to control measure: Evening subjective sleepiness, assessed using the Karolinska Sleepiness Scale after exposure to low vibration measure: Evening subjective sleepiness, assessed using the Karolinska Sleepiness Scale after exposure to intermediate vibration measure: Evening subjective sleepiness, assessed using the Karolinska Sleepiness Scale after exposure to high vibration measure: Morning subjective sleepiness, assessed using the Karolinska Sleepiness Scale after exposure to control measure: Morning subjective sleepiness, assessed using the Karolinska Sleepiness Scale after exposure to low vibration measure: Morning subjective sleepiness, assessed using the Karolinska Sleepiness Scale after exposure to intermediate vibration measure: Morning subjective sleepiness, assessed using the Karolinska Sleepiness Scale after exposure to high vibration measure: Self-reported sleep disturbance by vibration after control exposure measure: Self-reported sleep disturbance by vibration after exposure to low vibration measure: Self-reported sleep disturbance by vibration after exposure to intermediate vibration measure: Self-reported sleep disturbance by vibration after exposure to high vibration measure: Morning positive affect, assessed using the Positive and Negative Affect Schedule (PANAS) after control exposure measure: Morning positive affect, assessed using the Positive and Negative Affect Schedule (PANAS) after exposure to low vibration measure: Morning positive affect, assessed using the Positive and Negative Affect Schedule (PANAS) after exposure to intermediate vibration measure: Morning positive affect, assessed using the Positive and Negative Affect Schedule (PANAS) after exposure to high vibration measure: Morning negative affect, assessed using the Positive and Negative Affect Schedule (PANAS) after control exposure measure: Morning negative affect, assessed using the Positive and Negative Affect Schedule (PANAS) after exposure to low vibration measure: Morning negative affect, assessed using the Positive and Negative Affect Schedule (PANAS) after exposure to intermediate vibration measure: Morning negative affect, assessed using the Positive and Negative Affect Schedule (PANAS) after exposure to high vibration measure: Evening negative affect, assessed using the Positive and Negative Affect Schedule (PANAS) after exposure to control measure: Evening negative affect, assessed using the Positive and Negative Affect Schedule (PANAS) after exposure to low vibration measure: Evening negative affect, assessed using the Positive and Negative Affect Schedule (PANAS) after exposure to intermediate vibration measure: Evening negative affect, assessed using the Positive and Negative Affect Schedule (PANAS) after exposure to high vibration measure: Evening positive affect, assessed using the Positive and Negative Affect Schedule (PANAS) after exposure to control measure: Evening positive affect, assessed using the Positive and Negative Affect Schedule (PANAS) after exposure to low vibration measure: Evening positive affect, assessed using the Positive and Negative Affect Schedule (PANAS) after exposure to intermediate vibration measure: Evening positive affect, assessed using the Positive and Negative Affect Schedule (PANAS) after exposure to high vibration measure: Event-related cardiovascular activation in response to control measure: Event-related cardiovascular activation in response to low vibration measure: Event-related cardiovascular activation in response to intermediate vibration measure: Event-related cardiovascular activation in response to high vibration measure: Evening neurobehavioural speed measure: Evening neurobehavioural accuracy sex: ALL minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT facility: University of Gothenburg status: RECRUITING city: Gothenburg state: Västra Götaland zip: 42650 country: Sweden name: Michael G Smith, PhD role: CONTACT phone: +46317862843 email: michael.smith@amm.gu.se lat: 57.70716 lon: 11.96679 hasResults: False