hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06287372 id: 3261 briefTitle: Comparison of Changes in Intra-myocardial Amino Acids During Use of Calafiore and Modified Del Nido Cardioplegia overallStatus: COMPLETED date: 2022-07-04 date: 2023-07-04 date: 2023-07-04 date: 2024-03-01 date: 2024-03-07 name: Damascus University class: OTHER briefSummary: The aim of the present study was to investigate intra-operative changes in markers of myocardial injury and myocardial intracellular amino acids during ischemia and reperfusion, comparing two methods of myocardial protection; Calafiore intermittent antegrade warm blood cardioplegia or modified del Nido intermittent antegrade cold blood cardioplegia in routine coronary artery bypass grafting procedures. conditions: Myocardial Injury conditions: Cardiac Surgery conditions: Myocardial Protection studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 20 type: ACTUAL name: Cardioplegic solution measure: Changes in markers of myocardial injury measure: Changes in myocardial amino acid concentrations sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Damascus University Cardiac Surgery Hospital city: Damascus country: Syrian Arab Republic lat: 33.5102 lon: 36.29128 hasResults: False
nctId: NCT06287359 id: Local/2024/MP-01 briefTitle: Experience of Parents/Carers of Children With Severe Motor Disabilities Suffering From Spinal Pain? acronym: Vé-Quo-Pa-H-R overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-12 date: 2024-12 date: 2024-03-01 date: 2024-04-05 name: Centre Hospitalier Universitaire de Nīmes class: OTHER briefSummary: Parents of disabled children suffer from back pain more frequently than the general population. At present, the literature does not identify any specific factors responsible for this suffering.
With this in mind, the investigators are conducting a qualitative study to gain a better understanding of the day-to-day lives of these parents. conditions: Low Back Pain studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 15 type: ESTIMATED name: individual interviews measure: Individual interviews sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06287346 id: 240101 briefTitle: 5-Years PMCF Study of Ceramic Dental Implants One-piece Versus Two-piece. acronym: 240101 overallStatus: RECRUITING date: 2024-01-01 date: 2029-01-01 date: 2030-01-01 date: 2024-03-01 date: 2024-03-01 name: CeraRoot SL class: INDUSTRY briefSummary: The goal of this cohort observational study is to compare in the survival rate of ceramic dental implants placed in patients with missing or hopeless teeth . The main question\[s\] it aims to answer are:
* What are the complications associated to the procedure and differences between the two groups. conditions: Edentulism conditions: Tooth Loss studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 652 type: ESTIMATED name: dental implant measure: Survival rate measure: Complications sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Family Holistic Dentistry status: RECRUITING city: Boulder state: Colorado zip: 80303 country: United States name: CARMEN BURKE, DDS role: CONTACT phone: 303-219-0499 email: carmen@carmenburke.com name: CARMEN BURKE, DDS role: PRINCIPAL_INVESTIGATOR lat: 40.01499 lon: -105.27055 facility: CeraRoot CLINIC status: RECRUITING city: Les Franqueses del Vallès state: Barcelona zip: 08520 country: Spain name: JOSEP OLIVA-OCHOA, DDS MSC role: CONTACT phone: 800-485-1613 email: josep.oliva@cerarootclinic.com name: Ekaterina Treatment coordinator role: CONTACT phone: +34 935 950 247 email: ekaterina@ceraroot.com name: JOSEP OLIVA-OCHOA, DDS MSC role: PRINCIPAL_INVESTIGATOR name: XAVIER OLIVA-OCHOA, DDS MSC role: SUB_INVESTIGATOR name: CARLA OLIVA-PORTA, STUDENT role: SUB_INVESTIGATOR name: ARNAU OLIVA-PORTA, STUDENT role: SUB_INVESTIGATOR lat: 41.61929 lon: 2.29829 hasResults: False
nctId: NCT06287333 id: 2023PI221 briefTitle: Video-respiratory Polygraphy in Children overallStatus: NOT_YET_RECRUITING date: 2024-02-22 date: 2024-02-22 date: 2024-02-28 date: 2024-03-01 date: 2024-03-01 name: Central Hospital, Nancy, France class: OTHER briefSummary: The diagnosis of obstructive sleep apnea-hypopnea syndrome in children (OSAS) requires a polysomnography (PSG) in a sleep lab with video surveillance and monitoring by a nurse. But PSG is a cumbersome exam, sometimes difficult to perform in children. Simplified exams as respiratory polygraphy (RP) which uses only respiratory signals can be used for the diagnosis of OSAS but studies show that it underestimates the obstructive apnea-hypopnea index (OAHI) because the total sleep time cannot be accurately estimated. The use of a video camera with software synchronous with the RP software could compensate for this disadvantage, by estimating when the child is sleeping or not. conditions: Sleep Apnea, Obstructive studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 66 type: ESTIMATED name: Polysomnography in routine care measure: OAHI in video-RP significantly correlated with OAHI in PSG measure: Diagnostic ability of video-RP to identify OSAS in children measure: Diagnostic ability of video-RP to identify moderate-severe OSAS in children sex: ALL minimumAge: 2 Years maximumAge: 19 Years stdAges: CHILD stdAges: ADULT hasResults: False
nctId: NCT06287320 id: Bioplc briefTitle: The Predictive Biomarkers in Patients With Locally Advanced Non-small Cell Lung Cancer overallStatus: RECRUITING date: 2024-03-01 date: 2025-12-31 date: 2026-02-28 date: 2024-03-01 date: 2024-03-01 name: Cancer Institute and Hospital, Chinese Academy of Medical Sciences class: OTHER briefSummary: This study is a prospective cohort study to evaluate the peripheral blood lymphocyte subsets as predicative biomarkers reflecting the efficacy and toxicity in patients with locally advanced non-small cell lung cancer (NSCLC) received chemoradiotherapy (CRT) with or without immune checkpoint inhibitors (ICIs). conditions: Locally Advanced Non-small Cell Lung Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 200 type: ESTIMATED name: concurrent or sequential chemoradiotherapy name: Immunotherapy measure: Adverse Event measure: Progression-free survival (PFS) measure: Overall survival (OS) measure: Objective Response Rate (ORR) measure: Disease control rate (DCR) sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Chinese Academy of Medical Science and Peking Union Medical College status: RECRUITING city: Beijing state: Beijing zip: 100021 country: China name: Nan Bi, MD, PhD role: CONTACT email: binan_email@163.com lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06287294 id: RS23-042 briefTitle: An Investigation Into Taste Problems Associated With Xerostomia in Patients With Advanced Cancer overallStatus: RECRUITING date: 2023-08-30 date: 2024-12-31 date: 2024-12-31 date: 2024-03-01 date: 2024-03-01 name: Our Lady's Hospice and Care Services class: OTHER briefSummary: Taste problems and xerostomia (dry mouth) are common among patients with advanced cancer. These symptoms can affect the pleasure of eating and drinking, reduce dietary intake, cause low mood, and a lower quality of life. This study will explore the relationship between dry mouth and taste problems in patients with advanced cancer. conditions: Taste, Altered conditions: Xerostomia conditions: Neoplasms studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 120 type: ESTIMATED measure: To measure the prevalence of taste problems in patients with advanced cancer with a dry mouth using the Oral Symptom Assessment Scale (questionnaire) measure: To identify an association of any other oral symptoms present in patients with taste problems and dry mouth who have advanced cancer using the Oral Symptom Assessment Scale (questionnaire) measure: To characterise the taste disturbances i.e. to identify reduced taste, heightened taste, altered taste or no taste using the Taste Questionnaire in Palliative Care (questionnaire) and Waterless Empirical Taste Test (objective taste test) measure: To identify what impact taste problems are having on patients dietary intake using the Taste Questionnaire in Palliative Care (questionnaire). measure: To identify what impact taste problems are having on patients quality of life using the Taste Questionnaire in Palliative Care (questionnaire). sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Our Lady's Hospice and Care Services status: RECRUITING city: Dublin zip: D6WRY72 country: Ireland name: Andrew Davies, FRCP role: CONTACT phone: 0035314986235 email: andavies@tcd.ie name: Marie Hannon, BSc role: CONTACT phone: 0035314912558 email: marie.hannon@ucdconnect.ie lat: 53.33306 lon: -6.24889 hasResults: False
nctId: NCT06287281 id: Heel01 briefTitle: High-heeled Shoes in a Sample of Young Women overallStatus: RECRUITING date: 2023-12-15 date: 2024-02-15 date: 2024-02-28 date: 2024-03-01 date: 2024-03-01 name: Manusapiens class: OTHER briefSummary: At a postural level, many doctors, physiotherapists and chiropractors are convinced that lower back pain induced by heels is due to an increase in lumbar lordosis associated with an anterior pelvic tilt; this thought is even shared by the American Chiropractic Association and the American Physical Therapy Association.
The secondary outcome will be to verify in the sample analyzed whether there are different behaviors between the subgroups of those who have complained in their anamnesis and those who have never complained of lower back pain when using high-heeled shoes for a few hours. conditions: Low Back Pain conditions: Healthy studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 34 type: ESTIMATED name: heel hight shoes measure: effect of high-heeled shoes on trunk inclination measure: effect of high-heeled shoes on pelvic inclination measure: effect of high-heeled shoes on lordotic angle measure: effect of high-heeled shoes on kyphotic angle measure: effect of high-heeled shoes on lumbar arrow measure: effect of high-heeled shoes on cervical arrow measure: different response on trunk inclination between the subgroups (suffering from back pain and asymptomatic) measure: different response on pelvic inclination between the subgroups (suffering from back pain and asymptomatic) measure: different response on lordotic angle between the subgroups (suffering from back pain and asymptomatic) measure: different response on kyphotic angle between the subgroups (suffering from back pain and asymptomatic) measure: different response on lumbar arrow between the subgroups (suffering from back pain and asymptomatic) measure: different response on cervical arrow between the subgroups (suffering from back pain and asymptomatic) sex: FEMALE minimumAge: 20 Years maximumAge: 40 Years stdAges: ADULT facility: Spine Center status: RECRUITING city: Bologna zip: 40128 country: Italy name: Saverio Colonna, MD role: CONTACT phone: +39 051 095 2375 email: direzione@spine-center.it lat: 44.49381 lon: 11.33875 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2024-02-10 uploadDate: 2024-02-10T21:29 filename: Prot_SAP_000.pdf size: 222277 hasResults: False
nctId: NCT06287268 id: CETB115G1401 briefTitle: Revolade Tablets Specified Drug-use Survey overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2028-10-31 date: 2028-10-31 date: 2024-03-01 date: 2024-03-01 name: Novartis Pharmaceuticals class: INDUSTRY briefSummary: This is a multicenter, single-arm, non-interventional study (NIS) to confirm the safety and efficacy of eltrombopag in Anti-Thymocyte Globulin (ATG) treatment naive pediatric patients with aplastic anemia (AA). conditions: Aplastic Anemia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: OTHER count: 10 type: ESTIMATED name: eltrombopag measure: Occurrence of serious adverse events measure: Occurrence of adverse events and adverse drug reactions leading to treatment discontinuation measure: Occurrence of adverse events and adverse drug reactions applicable to safety specifications (hepatic dysfunction and hematopoietic malignancies) measure: Occurrence of clonal evolution measure: Hematologic response status measure: Change over time from baseline in platelet count measure: Change over time from baseline in hemoglobin measure: Change over time from baseline in neutrophil count measure: Change over time from baseline in reticulocyte count measure: Change over time from baseline in transfusion dependence measure: Change over time from baseline in transfusion volume sex: ALL minimumAge: 6 Years maximumAge: 17 Years stdAges: CHILD hasResults: False
nctId: NCT06287255 id: 2023H0314 briefTitle: Feasibility and Acceptability of Incorporating Smartwatches Into an Exercise is Medicine Program in Older Individuals acronym: EIM+ overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2025-09-30 date: 2025-09-30 date: 2024-03-01 date: 2024-03-01 name: Ohio State University class: OTHER briefSummary: The effects of exercise on prevention and improved control of chronic diseases, reduced mortality, and improved quality of life are well established. Exercise has been shown to prevent heart disease, stroke, type 2 diabetes, depression, and certain types of cancers. In addition to prevention, physical activity is included in the standard or care for many chronic diseases and used in treatment. For example, the American Diabetes Association has identified positive health behaviors like physical activity as foundational in the treatment and management of disease and improving overall quality of life.
The integration of technology among a 65+ population of EIM participants provides a novel approach to improving individual's health. Thus, our study aims to provide EIM participants aged 65+ with smartwatches in the hopes of increasing their overall physical activity levels. conditions: Physical Inactivity conditions: Obesity studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: A single-arm trial primaryPurpose: PREVENTION masking: NONE count: 150 type: ESTIMATED name: EIM+ measure: Feasibility of EIM+ measure: Acceptability of EIM+ measure: Change in physical activity measure: Change in weight measure: Change in BMI measure: Change in hip circumference measure: Change in waist circumference measure: Change in blood pressure measure: Change in heart rate variability measure: Change in hemoglobin A1c measure: Change in perceived stress measure: Change in depressive symptoms measure: Change in diet measure: Change in activity minutes per week measure: Change in daily steps total measure: Change in measured steps per minute measure: Change in sleep quality measure: Change in sleep duration measure: Change in estimated energy expenditure measure: Change in heart rate measure: Change in distance moved measure: Change in minutes of vigorous activity measure: Change in minutes of moderate activity measure: Change in minutes of light activity measure: Change in minutes of sedentary time measure: Change in number of manually entered and automatically detected physical activities (walking, running, etc.) measure: Change in quality of life measures sex: ALL minimumAge: 65 Years stdAges: OLDER_ADULT facility: The Ohio State University city: Columbus state: Ohio zip: 43202 country: United States name: Toluwa C Nafiu, B.S. role: CONTACT phone: 614-293-2404 email: toluwaniose.nafiu@osumc.edu name: Joshua Joseph, MD role: PRINCIPAL_INVESTIGATOR lat: 39.96118 lon: -82.99879 hasResults: False
nctId: NCT06287242 id: 24-01-282 briefTitle: Validation of the Cervicothoracic Differentiation Test acronym: EMU overallStatus: RECRUITING date: 2024-02-20 date: 2025-02 date: 2025-02 date: 2024-03-01 date: 2024-03-01 name: University of Hartford class: OTHER briefSummary: The goal of this clinical trial is to compare the effects of two spinal manipulations in adults between the ages of 18-65 based on the results of a non-invasive clinical test. The main question it aims to answer is: • Does matched or unmatched region of manipulation based on the CTDT result in greater reduction of pain levels and improvement in range of motion in adults with neck pain compared to unmatched manipulations? Participants will be asked to:
Researchers will compare the effects of manipulation matched to CTDT test result to individuals in the unmatched CTDT manipulation group to see if the CTDT may indicate which region will provide a greater treatment effect for individuals with neck pain. conditions: Neck Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE maskingDescription: Blinded research assistants will perform all baseline and follow-up measures. Investigator providing manipulation is blinded to group allocation (matched/unmatched) Participants will not be told if the CTDT indicates that they would benefit from cervical or thoracic manipulation, and the investigator performing the CTDT will only indicate which region is to be manipulated. All investigators are blinded to the work of the others and submit their results to an additional research assistant who will enter the data in a spreadsheet not accessible to the remainder of the research team until the conclusion of the study. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: spinal manipulation measure: pain with motion measure: pain at rest measure: range of motion measure: neck disability index sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Hartford status: RECRUITING city: West Hartford state: Connecticut zip: 06117 country: United States name: Brian Swanson, PT, DSc role: CONTACT phone: 860-768-5314 email: bswanson@hartford.edu lat: 41.76204 lon: -72.74204 hasResults: False
nctId: NCT06287229 id: 2023-0627 id: NCI-2024-01756 type: OTHER domain: NCI-CTRP Clinical Registry briefTitle: Phase Ib/II Study Assessing the Clinical Activity and Safety of Brexucabtagene Autoleucel as a Consolidation in Patients With Relapsed/Refractory (R/R) and Newly Diagnosed B-cell Acute Lymphocytic Leukemia (ALL) Post Cytoreduction With Mini-HCVD-inotuzumab-blinatumomab/HCVAD-inotuzumab-blinatumomab overallStatus: NOT_YET_RECRUITING date: 2024-08-31 date: 2028-12-31 date: 2030-12-31 date: 2024-03-01 date: 2024-04-12 name: M.D. Anderson Cancer Center class: OTHER briefSummary: To learn about the safety of giving the drug brexucabtagene autoleucel to participants with relapsed/refractory B-cell ALL after treatment with inotuzumab ozogamicin, blinatumomab, and either hyper-CVAD or mini-hyper-CVD. Also, to learn if giving brexucabtagene autoleucel to patients with relapsed/refractory or high-risk, newly diagnosed B-cell ALL after treatment with inotuzumab ozogamicin, blinatumomab, and either hyper-CVAD or mini-hyper-CVD can help to control the disease. conditions: Relapsed/Refractory conditions: B-cell Acute Lymphocytic Leukemia studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 40 type: ESTIMATED name: Blinatumomab name: Inotuzumab Ozogamicin name: Hyper-CVAD name: Mini-hyper-CVD measure: Safety and adverse events (AEs) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: MD Anderson Cancer Center city: Houston state: Texas zip: 77030 country: United States name: Elias Jabbour, MD role: CONTACT phone: 713-792-4764 email: ejabbour@mdanderson.org name: Elias Jabbour, MD role: PRINCIPAL_INVESTIGATOR lat: 29.76328 lon: -95.36327 hasResults: False
nctId: NCT06287216 id: 2024001 briefTitle: Preliminary Evaluation of a Mental Health Program: a Comparison Study overallStatus: NOT_YET_RECRUITING date: 2024-02-29 date: 2024-04-30 date: 2024-04-30 date: 2024-03-01 date: 2024-03-01 name: The Royal Ottawa Mental Health Centre class: OTHER briefSummary: The mental hygiene challenge is a Royal Ottawa Health Care Group led initiative to engage the staff, clients and community members to attend to their mental well-being by way of practicing mental hygiene activities for 10 min on a daily basis, throughout the month of March. Participants are encouraged to choose one or many of the practices recommended and do them for about 10 minutes a day. Participants are encouraged to make it their own, in that they can combine the practice or tailor them in a way that suits them best. When signing up for the challenge, participants receive free access to a toolkit with brief outlines and instructional videos on various mental hygiene practices.
We also encourage participants to divide the 10 minutes in whatever way best works for them, such as 10 minutes all at once, 5 minutes twice, or even 2 minutes five times. This study aims to expand on the work that was done in 2022 and 2023, when the World Health Organization - 5 Wellbeing Index (WHO-5) and the Warwick Edinburgh Mental Wellbeing Scale (WEMWBS) were collected from participants to ascertain the impact of mental hygiene, by way of including a control group. conditions: Mental Wellbeing studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: PREVENTION masking: SINGLE whoMasked: PARTICIPANT count: 200 type: ESTIMATED name: Mental Hygiene name: Self-Care measure: Change in level of mental wellbeing as measured by the WHO-5 index. measure: Change in level of mental wellbeing as measured by the WEMWBS. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06287203 id: Pro2023001498 id: 3R01DA050721-04S1 type: NIH link: https://reporter.nih.gov/quickSearch/3R01DA050721-04S1 briefTitle: Novel Prevention Intervention Program to Reduce Risky Patterns of Substance Use Among Emerging Adults acronym: ARFP overallStatus: NOT_YET_RECRUITING date: 2024-03-20 date: 2024-11-20 date: 2024-11-20 date: 2024-03-01 date: 2024-03-01 name: Rutgers, The State University of New Jersey class: OTHER name: National Institute on Drug Abuse (NIDA) briefSummary: The purpose of this research study is to test whether completion of a new personalized feedback program is associated with reductions in risky substance use among emerging adults (18-25 years of age). conditions: Substance Use studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE maskingDescription: Participants will not be made aware of their condition at baseline; however, they will know their condition once they receives their estimates (or not, in the case of the control condition) and are taken to their follow-up resources. count: 450 type: ESTIMATED name: Addiction Risk Feedback Program measure: Alcohol Consumption measure: Alcohol Problems measure: Drug Use Problems measure: Readiness to change measure: Future substance use intentions measure: Worry About Substance Use Disorders measure: Perceived Susceptibility measure: Well-Being measure: Anxiety and Depressive Symptoms measure: Addiction Risk Program Satisfaction measure: Feelings About Results measure: Satisfaction with the Assigned Conditions sex: ALL minimumAge: 18 Years maximumAge: 25 Years stdAges: ADULT facility: Rutgers Robert Wood Johnson Medical School city: Piscataway state: New Jersey zip: 08854 country: United States name: Emily Balcke role: CONTACT email: dnadiscoverystudy@rutgers.edu name: Danielle Dick, PhD role: PRINCIPAL_INVESTIGATOR lat: 40.49927 lon: -74.39904 hasResults: False