hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06375928 id: CARPEDIEM-1 briefTitle: EUS-guided Choledochoduodenostomy vs ERCP as First Line in Malignant Distal Obstruction in Resectable Disease (CARPEDIEM-1 Trial) overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-02-01 date: 2026-05-01 date: 2024-04-19 date: 2024-04-19 name: Hospital Universitari de Bellvitge class: OTHER name: Hospital Mutua de Terrassa name: Hospital Clínico Universitario de Valencia name: Hospital General Universitario de Alicante name: Hospital Universitario Ramon y Cajal name: Hospital General Universitario de Castellón name: Hospital Álvaro Cunqueiro name: Complejo Hospitalario Universitario de Santiago name: University Hospital Virgen de las Nieves name: Complejo Hospitalario de Navarra name: Hospital de Sant Pau name: University of Salamanca briefSummary: The aim of this clinical trial is to evaluate temporal delay (days) between biliary drainage (EUS-CDS vs ERCP as first line therapy) and surgery in patients with resectable distal malignant biliary obstruction. conditions: Malignant Biliary Obstruction conditions: Pancreatic Cancer Resectable conditions: Biliary Tract Neoplasms studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 44 type: ESTIMATED name: Endoscopic biliary drainage name: Self-expandable metallic stent (SEMS) name: Lumen-apposing metal stent (LAMS) and double-pigtail plastic stent (DPPS) measure: Delay in days between endoscopic biliary drainage and cephalic duodenopancreatectomy (CDP) measure: Technical success measure: Clinical success measure: AE - biliary drainage measure: AE - surgery sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hospital Universitari de Bellvitge city: L'Hospitalet de Llobregat state: Barcelona, Catalonia zip: 08907 country: Spain name: Joan B Gornals, MD, PhD role: CONTACT phone: +34 93 260 76 82 phoneExt: 2624 email: jgornals@bellvitgehospital.cat name: Maria Puigcerver-Mas, MD role: CONTACT phone: +34 687332007 email: mariapuigcervermas@gmail.com name: Julia Escuer-Turu, MD role: SUB_INVESTIGATOR name: Daniel Luna Rodriguez, MD role: SUB_INVESTIGATOR name: Albert Sumalla, MD role: SUB_INVESTIGATOR name: Berta Laquente, MD, PhD role: SUB_INVESTIGATOR name: Juli Busquets, MD, PhD role: SUB_INVESTIGATOR name: Julio Velasquez Rodriguez, MD role: SUB_INVESTIGATOR name: Sandra Maisterra, MD role: SUB_INVESTIGATOR name: Carme Loras, MD, PhD role: PRINCIPAL_INVESTIGATOR name: Charly Guarner Argente, MD, PHD role: PRINCIPAL_INVESTIGATOR name: Jose Lariño, MD, PhD role: PRINCIPAL_INVESTIGATOR name: Rafael Pedraza, MD role: PRINCIPAL_INVESTIGATOR name: Jose Ramon Aparicio, MD, PhD role: PRINCIPAL_INVESTIGATOR name: Vicente Sanchiz, MD, PhD role: PRINCIPAL_INVESTIGATOR name: Eduardo Redondo, MD, PhD role: PRINCIPAL_INVESTIGATOR name: Juan J Vila, MD, PhD role: PRINCIPAL_INVESTIGATOR lat: 41.35967 lon: 2.10028 hasResults: False
nctId: NCT06375902 id: 2022289RNA briefTitle: The Fragility of Metaphors (FraMe): Learning, Loosing, and How to Train Them acronym: FRAME overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-10 date: 2025-10 date: 2024-04-19 date: 2024-04-19 name: IRCCS San Raffaele class: OTHER briefSummary: Tracking down the difficulties in metaphor comprehension experienced by individuals with schizophrenia across different metaphor types and exploring the neurological correlates via EEG recording technique conditions: Schizophrenia; Psychosis studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 64 type: ESTIMATED name: PragmaCom measure: Tracking down the difficulties in metaphor comprehension via a behavioural task measure: Tracking down the difficulties in metaphor comprehension via task during electrophysiological recording measure: Evaluation of psychopathology measure: Evaluation of cognition measure: Evaluation of Theory of Mind measure: Evaluation of functioning measure: Evaluate the efficacy of a rehabilitative training in restoring metaphor comprehension ability sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06375889 id: 69HCL24_0250 id: 2024-A00796-41 type: OTHER domain: ID-RCB briefTitle: Platelet Activation in Delayed Cerebral Ischemia Secondary to Aneurysmal Subarachnoid Hemorrhage acronym: APICRASH overallStatus: NOT_YET_RECRUITING date: 2024-05-13 date: 2025-06-13 date: 2025-06-13 date: 2024-04-19 date: 2024-04-19 name: Hospices Civils de Lyon class: OTHER briefSummary: Aneurysmal subarachnoid haemorrhage is a complex pathology, the pathophysiology of which is still imperfectly understood. Its morbidity and mortality remain significant. In addition to the damage sustained by the brain in the immediate aftermath of aneurysmal rupture, which is inaccessible to life-saving treatment, a significant proportion of lesions occur at a distance from the initial event. Delayed cerebral ischaemia is one of the most morbid complications. It combines an inflammatory pattern with vascular dysfunction and neuronal excitotoxicity, leading to avoidable secondary neuronal loss.
It therefore seems appropriate to propose temporal monitoring of platelet activation kinetics over time, combined with concomitant collection of markers of endothelial damage, in order to clarify the vascular chronobiology of this pathology. conditions: Aneuvrysmal Subarachnoid Hemorrhage conditions: Delayed Cerebral Ischemia conditions: Endotheliopathy conditions: Platelets Kinetic studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 40 type: ESTIMATED name: blood test measure: The difference in the percentage of platelets expressing P-selectin, reflecting their irreversible activation. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Anaesthesiology and Intensive Care medicine department, Pierre Wertheimer hospital city: Bron state: Auvergne-Rhône-Alpes zip: 69005 country: France name: Nicolas Chardon, MD;Msc role: CONTACT phone: 683396245 phoneExt: 33 email: nicolas.chardon@chu-lyon.fr name: Nicolas Chardon, MD;msc role: PRINCIPAL_INVESTIGATOR lat: 45.73333 lon: 4.91667 facility: Neurovascular intensive care unit department, Pierre Wertheimer hospital city: Bron state: Auvergnes-Rhones-Alpes zip: 69005 country: France name: Nicolas Chardon, MD;Msc role: CONTACT phone: 683396245 phoneExt: 33 email: nicolas.chardon@chu-lyon.fr name: Nicolas Chardon, MD;Msc role: PRINCIPAL_INVESTIGATOR lat: 45.73333 lon: 4.91667 hasResults: False
nctId: NCT06375876 id: 2000034173 id: 15JOVW-22-GG-04755-STOP type: OTHER_GRANT domain: Office on Violence Against Women (OVW) briefTitle: Single Session Intervention to Promote Hope overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-04 date: 2025-04 date: 2024-04-19 date: 2024-04-26 name: Yale University class: OTHER name: Office on Violence Against Women (OVW) briefSummary: The purpose of this study is to develop a brief, self-guided single-session intervention (SSI) that targets the development of, or increase in, hope, and pilot test it for the primary outcomes of feasibility, acceptability/likeability, safety, and changes in hope, and the secondary outcomes of self-worth, empowerment, and emotional wellbeing among women experiencing intimate partner violence (IPV). The study will be conducted in 2 stages: intervention development (Intervention Development Stage), and pilot testing the intervention (Pilot Stage). The focus of this registration is the Pilot Stage. conditions: Domestic Violence studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 65 type: ESTIMATED name: Single-session intervention (SSI) measure: Feasibility assessed by percent enrolled measure: Feasibility assessed by time to complete measure: Feasibility assessed by post-intervention survey/process supplement measure: Acceptability/likability assessed using the Program Feeback Scale measure: Safety assessed using end of study survey measure: Change in Hope assessed using Herth Hope Index measure: Change in Hope assessed using Trait Hope Scale measure: Change in Hope assessed using Beck Hopelessness Scale (single item) measure: Change in Self-worth measure: Change in Empowerment assessed using The Personal Progress Scale-Revised (PPS-R) measure: Change in Emotional wellbeing measured by the Patient Health Questionnaire-2 (PHQ-2) measure: Change in Emotional wellbeing measured by the State Joy Scale sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Consultation Center at Yale city: New Haven state: Connecticut zip: 06511 country: United States name: Ashley Clayton role: CONTACT phone: 203-623-9830 email: ashley.clayton@yale.edu lat: 41.30815 lon: -72.92816 hasResults: False
nctId: NCT06375863 id: 44-2023 briefTitle: QT Changes in Geriatric Patients: a Comparison of Spinal and General Anesthesia overallStatus: COMPLETED date: 2023-03-29 date: 2023-05-29 date: 2023-05-29 date: 2024-04-19 date: 2024-04-19 name: Haseki Training and Research Hospital class: OTHER briefSummary: QT interval, defined as the time between the beginning of the QRS complex and the end of the T wave in electrocardiography (ECG), is an indicator of depolarization and repolarization of the myocardium.11 Prolongation of the heart rate corrected QT (QTc) interval reflects electrical instability of ventricles and is associated with life-threatening ventricular arrhythmias, including torsade de pointes, ventricular fibrillation and sudden cardiac death.
Spinal anesthesia can cause profound prolongation of the QTc interval due to disparity between lumbar and thoracic sympathetic activity following subarachnoid block. Meanwhile inhalational anesthetics, sevoflurane, isoflurane, and desflurane are known to prolong QTc interval and intravenous anesthetics such as propofol, thiopental, etomidate and ketamin can also cause remarkable prolongation of the QTc interval. Moreover laryngoscopy and intubation may contribute to prolongation of the QTc interval because of the sympathetic stimulation.
To the best of knowledge, there was no published study to compare spinal anesthesia and inhalational anesthesia in elderly patients with regard to the QT interval changes. Investigators aimed to investigate the effects of spinal anesthesia on QT, QTc intervals and to compare general anesthesia with sevofluran in elderly patients. conditions: Anesthesia, Spinal conditions: Sevoflurane conditions: Long QT Syndrome studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: DIAGNOSTIC masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 58 type: ACTUAL name: QT and QTc interval measure: QTc interval measure: QT sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Health Science University, Haseki Training and Research Hospital city: Istanbul country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06375850 id: Effects of topical sesame oil briefTitle: Effects of Topical Sesame Oil in the Prevention of Peripheral Venous Catheter Phlebitis: Clinical Trial. overallStatus: RECRUITING date: 2022-06-05 date: 2025-02-11 date: 2025-05-11 date: 2024-04-19 date: 2024-04-19 name: Hospital Universitario Marqués de Valdecilla class: OTHER briefSummary: Cancer is a disease that, despite having a higher cure rate, is currently on the rise, with an increase in the number of diagnoses.
With the use of topical sesame oil, and thanks to its anti-inflammatory properties, the investigators intend to study whether it is effective in preventing the appearance of phlebitis. conditions: Phlebitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 300 type: ESTIMATED name: Sesame oil name: Saline solution measure: Number of phlebitis in oncology patients with peripheral catheter to whom sesame oil is applied topically measure: Other adverse effects that appear in relation to the topical application of sesame oil in patients with peripheral catheters sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hospital Universitario Marqués de Valdecilla status: RECRUITING city: Santander state: Cantabria zip: 39008 country: Spain name: Virginia Meneses Campos role: CONTACT phone: +34942202520 email: virginia.meneses@scsalud.es name: Virginia Meneses Campos role: PRINCIPAL_INVESTIGATOR lat: 43.46472 lon: -3.80444 hasResults: False
nctId: NCT06375837 id: bioactive-NCCLs briefTitle: Comparative Evaluation of an Alkasite-based Restorative Material and Two Different Resin Composites overallStatus: RECRUITING date: 2024-04-15 date: 2024-06-15 date: 2026-06-15 date: 2024-04-19 date: 2024-04-19 name: Hacettepe University class: OTHER briefSummary: The clinical performance of an an alkasite-based restorative material and two different resin composites will be evaluated and compared in non-carious cervical lesions. After recruiting participants with at least three non-carious cervical lesions, all restorations will be placed by a single clinician. Lesions will be divided in three groups: an alkasite-based restorative material (Cention N, Ivoclar Vivadent, Schaan, Liechtenstein (CN)), hybrid resin composite (Gradia Direct Anterior, GC, Tokyo, Japan (GD)) and a highly filled flowable resin composite ((G-aenial Universal Flo, GC, Tokyo, Japan (GF)). All restorative procedures will be conducted according to manufacturers' instructions. Restorations will be scored using FDI criteria. Descriptive statistics will be performed using chi-square tests. conditions: Tooth Diseases studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 33 type: ESTIMATED name: an alkasite-based restorative material name: hybrid resin composite name: a highly filled flowable resin composite measure: Clinical performances of different restorative systems according to FDI criteria (Esthetic properties) measure: Clinical performances of different restorative systems according to FDI criteria (Functional properties) measure: Clinical performances of different restorative systems according to FDI criteria (Biological properties) sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hacettepe University status: RECRUITING city: Ankara country: Turkey name: Fatma Oz role: CONTACT lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06375824 id: TCM for Pre-COPD briefTitle: Bufei Recipe Reduces the Incidence Rate of COPD overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-04-30 date: 2027-10-31 date: 2024-04-19 date: 2024-04-19 name: Henan University of Traditional Chinese Medicine class: OTHER name: West China Hospital name: The First Affiliated Hospital of Zhejiang Chinese Medical University briefSummary: Establish early TCM prevention and treatment program to reduce the incidence rate of COPD. conditions: Preserved Ratio Impaired Spirometry studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 1100 type: ESTIMATED name: Bufei Recipe name: Bufei Recipe placebo measure: Incidence rate of COPD measure: FVC measure: FEV1 measure: FEV1% pred measure: FEV1/FVC measure: IPAG-Q measure: LFQ measure: COPD-PS measure: CAT measure: SF-36 measure: Clinical symptoms measure: Biochemical indicators sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06375798 id: 2020137 briefTitle: Clinical Study of Breast Conserving Surgery Combined With Intraoperative Radiotherapy for Early Breast Cancer overallStatus: RECRUITING date: 2020-11-19 date: 2026-11-19 date: 2026-11-19 date: 2024-04-19 date: 2024-04-19 name: Hebei Medical University Fourth Hospital class: OTHER briefSummary: A Single-center, open, prospective study，for analyzing the local recurrence rate, the incidence of incision complications and the aesthetic effect of intraoperative radiotherapy in early breast cancer patients after breast-conserving surgery. conditions: Breast Cancer conditions: HER2-negative Breast Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 620 type: ESTIMATED name: radiotherapy measure: LRFS sex: FEMALE minimumAge: 55 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Fourth Hospital of Hebei Medical University status: RECRUITING city: Shijiazhuang state: Hebei country: China name: qimei wang, attending role: CONTACT phone: 18633051639 email: maggie92320@hotmail.com lat: 38.04139 lon: 114.47861 hasResults: False
nctId: NCT06375785 id: LSVT-BIG vs Otago briefTitle: Two Different Exercise Methods in Geriatrics overallStatus: COMPLETED date: 2023-03-01 date: 2023-06-01 date: 2024-03-01 date: 2024-04-19 date: 2024-04-23 name: Halic University class: OTHER name: Fenerbahce University name: Istanbul Galata University name: Biruni University briefSummary: The aim of the study is to compare slow rhythmic exercises with large amplitude exercises in elderly people conditions: Elderly People conditions: Nursing Homes studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 70 type: ACTUAL name: Otago-based (slow rhythmic) exercise group name: LSVT BIG-based (large amplitude) exercise group measure: Timed Up &Go Test measure: Performanz Balance System measure: Functional Reaching Test measure: Six Minute Walking Test measure: Tinetti Balance and Gait Assessment measure: Activity-Specific Balance and Confidence Scale measure: Five Times Sit to Stand measure: Montreal Cognitive Assessment Test measure: KATZ Activities of Daily Living Scale measure: Clinical Frailty Scale sex: ALL minimumAge: 65 Years maximumAge: 80 Years stdAges: OLDER_ADULT facility: Haliç University city: Istanbul state: Eyüpsultan country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06375772 id: 2-DG-02 briefTitle: A Controlled Human Rhinovirus Infection Study of 2-Deoxy-D-Glucose in Healthy Adults overallStatus: RECRUITING date: 2024-04-02 date: 2024-08-31 date: 2024-12-31 date: 2024-04-19 date: 2024-04-19 name: G.ST Antivirals GmbH class: INDUSTRY briefSummary: 2-DG-02 is a randomized, placebo-controlled, double-blind Phase 2 study to investigate the efficacy and safety of 2-Deoxy-D-Glucose as a pre-exposure prophylaxis using the rhinovirus challenge model in healthy study participants. conditions: Acute Nasopharyngitis studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 128 type: ESTIMATED name: 2-Deoxy-D-glucose name: Placebo measure: The difference in the rate of rhinovirus-associated illness between 2-DG and placebo measure: Number of infected subjects measure: Difference in percent of infected subjects measure: Difference in percent of days virus positive measure: Difference in peak nasal virus load measure: Difference in AUC nasal virus load measure: Difference in Total Jackson Symptom Score measure: Duration of illness measure: Difference in percent of days Jackson Symptom Score positive measure: Difference in Peak Jackson Symptom Score measure: Difference in peak total WURSS-21 measure: Difference in AUC total WURSS-21 measure: Occurrence of adverse events (AEs) and adverse drug-reactions (ADRs) measure: Biodistribution of multiple doses of 2-DG in plasma samples measure: Biodistribution of multiple doses of 2-DG in nasal wash samples sex: ALL minimumAge: 18 Years maximumAge: 64 Years stdAges: ADULT facility: Centre for Human Drug Research status: RECRUITING city: Leiden zip: 2333 country: Netherlands name: Ingrid de Visser- Kamerling, PhD role: CONTACT phone: +31 71 5246400 email: clintrials@chdr.nl lat: 52.15833 lon: 4.49306 hasResults: False
nctId: NCT06375759 id: XWSSB briefTitle: Subarachnoid-Subarachnoid (S-S) Bypass Versus Adhesion Lysis in Spinal Arachnoiditis and Syringomyelia overallStatus: RECRUITING date: 2024-04 date: 2025-04 date: 2027-04 date: 2024-04-19 date: 2024-04-19 name: Xuanwu Hospital, Beijing class: OTHER briefSummary: To determine whether Subarachnoid-Subarachnoid (S-S) Bypass results in better patient outcomes with fewer complications and improved quality of life compared to intradural adhesion lysis in individuals with Spinal Arachnoiditis and Syringomyelia. conditions: Syringomyelia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 200 type: ESTIMATED name: Subarachnoid-Subarachnoid (S-S) Bypass name: Intradural Adhesion Lysis measure: complication measure: improvement or resolution of the syrinx, measure: ASIA score measure: Klekamp and Sammi syringomyelia scale measure: modified Japanese Orthopaedic Association Scores (mJOA) measure: xuanwu syringomyelia scale sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fengzeng Jian status: RECRUITING city: Beijing state: Beijing zip: 100053 country: China name: Yuan Chenghua role: CONTACT email: yuanchenghua@ccmu.edu.cn name: Jian Fengzeng role: CONTACT email: jianfengzeng@xwh.ccmu.edu.cn name: jian guan, dr role: SUB_INVESTIGATOR lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06375746 id: 0091-22-WOMC briefTitle: The Impact of a Customized Informative Video Prior to Induction of Labor on Anxiety Relieve - a Randomized Controlled Trial overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-08-01 date: 2024-08-31 date: 2024-04-19 date: 2024-04-19 name: Wolfson Medical Center class: OTHER_GOV briefSummary: To determine whether watching a personalized video prior to medically indicated labor induction among term parturients reduces anxiety levels according to the STAI questionnaire, compared to a standard counselling. conditions: Induction of Labor Affected Fetus / Newborn studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 180 type: ESTIMATED name: Personalized video measure: STAI questionnaire score measure: satisfaction questionnaire sex: FEMALE minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT hasResults: False
nctId: NCT06375733 id: GFH009X1202 briefTitle: A Study of GFH009 in Combination With Zanubrutinib in Subjects With Relapsed or Refractory DLBCL overallStatus: RECRUITING date: 2024-03-20 date: 2026-12-31 date: 2026-12-31 date: 2024-04-19 date: 2024-04-19 name: Zhejiang Genfleet Therapeutics Co., Ltd. class: INDUSTRY briefSummary: This is a multicentre, open-label phase Ib/II study. The purpose of the study is to assess the safety and efficacy of GFH009 in combination with Zanubrutinib in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) conditions: Large B-cell Lymphoma studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 51 type: ESTIMATED name: GFH009 name: Zanubrutinib name: GFH009 name: Zanubrutinib measure: Phase Ib: adverse events(AEs) measure: Phase II: ORR sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Guangxi Medical University Cancer Hospital&Guangxi Cancer Institute status: RECRUITING city: Nanning country: China name: Cen Hong role: CONTACT lat: 22.81667 lon: 108.31667 facility: Affiliated Cancer Hospital of Zhengzhou University Henan Cancer Hospital status: RECRUITING city: Zhengzhou country: China name: Keshu Zhou role: CONTACT lat: 34.75778 lon: 113.64861 hasResults: False