hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06331975 id: IEO 0836 briefTitle: Radiomics and Radiogenomics of Non-small Cell Lung Cancer overallStatus: COMPLETED date: 2018-06-12 date: 2023-01-31 date: 2023-09-14 date: 2024-03-26 date: 2024-03-26 name: European Institute of Oncology class: OTHER briefSummary: In this study, the radiomic characteristics and a broad range of genetic aberrations in lung adenocarcinomas will be evaluated. Investigators will assess changes in the radiomic and genetic profiles during targeted therapies in a subset of patients harboring treatable mutations. Patients undergoing targeted therapies will also be evaluated for variations in genomic profile and radiomic signature during follow-up conditions: Non Small Cell Lung Cancer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 91 type: ACTUAL name: Radiomic signature measure: Evaluation of the association between the status of Epidermal Growth Factor Receptor (EGFR), Anaplastic Lymphoma Kinase (ALK), Kirsten Rat Sarcoma Virus (KRAS) and nodal status measure: Evaluation of the association between the status of EGFR, ALK, KRAS and overall survival (OS) measure: Evaluation of the association between the status of EGFR, ALK, KRAS and disease free survival (DFS) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: European Institute of Oncology city: Milan country: Italy lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06331962 id: B-ER-112-010 briefTitle: Digestive Tract Cancer and CIPN overallStatus: RECRUITING date: 2023-05-19 date: 2025-07-31 date: 2025-07-31 date: 2024-03-26 date: 2024-03-26 name: National Cheng-Kung University Hospital class: OTHER name: National Cheng Kung University briefSummary: According to the incidence rate of cancer, the digestive tract cancer accounts for two of the top ten cancers. It also accounts for half of the top ten causes of cancer death. Chemotherapy remains one of the most common forms of cancer treatment, and chemotherapy-induced peripheral neuropathy (CIPN) is one of the common adverse effects of cancer treatment in cancer survivors. To date, there is no exercise guideline established for patients with CIPN; therefore, CIPN remains quite threatening to cancer survivors. Due to limited studies on effects of exercise on improvement of CIPN symptoms in patients with digestive tract cancers, this study aims to investigate the effects of exercise and different intervention delivery modes (remote home exercise and exercise under supervision) at different time points on the CIPN symptoms, body inflammatory index, physical function, and quality of life of gastrointestinal cancer survivors with chemotherapy-induced peripheral neuropathy. conditions: Digestive Tract Cancer conditions: Chemotherapy-induced Peripheral Neuropathy conditions: Remote Exercise studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 90 type: ESTIMATED name: remote home-based exercise therapy group name: supervised exercise therapy group name: regular care group measure: Basic information measure: gene measure: body height measure: body weight measure: body mass index measure: blood data measure: Questionnaire of Quality of Life measure: Questionnaire of Chemotherapy-Induced Peripheral Neuropathy measure: Muscle Strength measure: Dynamic Balance measure: Sensation Test measure: Cardiovascular Endurance sex: ALL minimumAge: 20 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Physical Therapy, National Cheng-Kung University status: RECRUITING city: Tainan zip: 701 country: Taiwan name: Cheng-Feng Lin, Ph.D role: CONTACT lat: 22.99083 lon: 120.21333 hasResults: False
nctId: NCT06331949 id: TR TOKAT02 briefTitle: Video Supported Training on Non-Stress Test Application to Pregnant Women overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-11-01 date: 2024-11-01 date: 2024-03-26 date: 2024-03-26 name: Hilal Özbek class: OTHER briefSummary: Women go through many practices during their pregnancy. These practices, along with ignorance, create stress in the mother. However, performing the procedures for the first time may increase the mother's stress level. Stress during pregnancy also affects prenatal attachment. Non-Stress Test (NST) Application is a test applied to pregnant women starting from the 28th week of pregnancy and provides information about the baby's well-being and uterine contractions. There is a gap in the literature regarding education for pregnant women undergoing NST regarding stress levels and prenatal attachment. With this study, stress levels and prenatal attachment levels in pregnant women will be determined during NST, which is frequently applied during pregnancy. Additionally, the effects of midwifery care in this process will be realized. In this way, solutions will be produced for problems that may arise. A better quality of midwifery care will be provided conditions: First Pregnancy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: PARTICIPANT count: 74 type: ESTIMATED name: video assisted training measure: State-Trait Anxiety Scale measure: Prenatal Attachment Inventory (PAI) measure: State-Trait Anxiety Scale measure: Prenatal Attachment Inventory (PAI) measure: State-Trait Anxiety Scale measure: Prenatal Attachment Inventory (PAI) sex: FEMALE minimumAge: 18 Years maximumAge: 49 Years stdAges: ADULT hasResults: False
nctId: NCT06331936 id: Shenzhen Project briefTitle: Improving Emotional Regulation Skills of Children in Difficulty in Shenzhen overallStatus: RECRUITING date: 2024-01-06 date: 2024-06 date: 2024-09 date: 2024-03-26 date: 2024-03-26 name: City University of Hong Kong class: OTHER name: International Social Service Hong Kong Branch briefSummary: The study aims to 1) improve the emotional regulation strategies of children in difficulty in Shenzhen, and 2) develop and publish a set of evidence-based intervention manuals for professional use. Based on the intervention manual design of the researchers' previous study conducted in Hong Kong, the current research revised the intervention manual to adapt to the context of mainland China. This study adopts a randomized wait-list control trial design. The researchers aim to recruit 200 children in difficulty aged 8 to 14 as participants and randomly assign them to an experimental and a wait-list control group with a ratio of 3:2. Each participant will attend four sessions of intervention and one booster session, and each session requires around 1.5 to 2 hours to complete. The participants will complete assessments before the first session of the intervention (T1), immediately after the fourth session of the intervention (T2), and one month after the completion of the intervention (T3). A qualitative assessment will also be conducted after the booster session. conditions: Emotion Regulation conditions: Parent-Child Relations conditions: Happiness conditions: Positive Affect studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Children will be randomly assigned to two groups: intervention and waitlist control groups. Children in the waitlist control group will receive experimental intervention after treatment for the experimental group finishes. primaryPurpose: PREVENTION masking: SINGLE maskingDescription: At the recruitment phase, the participants and the social workers who lead the intervention will not know which arm the participants will be assigned. A cluster of approximately 10 participants formed a group based on their attendance date in the intervention program. This group will be randomly assigned to one of the two intervention arms through pre-prepared randomization list calculated by random allocation software. whoMasked: PARTICIPANT count: 200 type: ESTIMATED name: Emotion regulation measure: 10-item Emotional Management Strategy Questionnaire measure: 10-item Positive and Negative Affect Schedule measure: Patient Health Questionnaire-9 measure: Generalized Anxiety Disorder Scale measure: Subjective Happiness Scale measure: Connor-Davidson Resilience Scale 10-Item measure: Child-Parent Relationship Scale measure: Family Harmony Scale sex: ALL minimumAge: 8 Years maximumAge: 14 Years stdAges: CHILD facility: City University of Hong Kong status: RECRUITING city: Hong Kong country: China name: Nancy Xiaonan YU, Ph.D. role: CONTACT phone: (852)34429436 email: nancy.yu@cityu.edu.hk lat: 22.39407 lon: 114.13737 hasResults: False
nctId: NCT06331923 id: U1111-1305-0484 briefTitle: Assessing the Effectiveness of Continuous Glucose Monitoring in Enhancing Surgical Outcomes for Diabetic Patients overallStatus: RECRUITING date: 2024-04-12 date: 2025-10-31 date: 2025-12-31 date: 2024-03-26 date: 2024-04-16 name: Beijing Tsinghua Chang Gung Hospital class: OTHER name: Peking University International Hospital name: Wang Jing Hospital name: ZhuHai Hospital name: Beijing Hospital name: Siyang County Hospital of Traditional Chinese Medicine name: Second Hospital of Shanxi Medical University name: Henan Provincial Chest Hospital name: Fuzhou First Hospital name: Pinggu Hospital of Beijing Traditional Chinese Medicine Hospital name: The First Affiliated Hospital of Anhui University of Chinese Medicine name: The First Affiliated Hospital of Zhengzhou University name: Mindong Hospital of Ningde name: The Fifth Hospital of Xiamen name: People's Hospital of Ningxia Hui Autonomous Region name: The First People's Hospital of Changzhou name: The Fifth hospital of Deyang name: Suzhou Municipal Hospital name: Tang-Du Hospital name: Yiyang Central Hospital name: First Affiliated Hospital of Xinjiang Medical University name: Peng Ding Shan Shi Zhong Yi Yi Yuan name: Yueyang Central Hospital name: The First People's Hospital of Lianyungang name: Haimen District Traditional Chinese Medicine Hospital name: The 910th Hospital name: The Second Affiliated Hospital of Zhejiang Chinese Medical University name: Beijing Tiantan Hospital name: Affiliated Hospital of Jiangsu University name: Liaocheng People's Hospital name: Beijing Chao Yang Hospital name: Jilin City Hospital of Chemical Industry name: Creen Hospital-465 name: Wuhan Central Hospital name: Air Force Military Medical University, China name: Shanghai Tong Ren Hospital name: Beijing Anzhen Hospital name: Emergency General Hospital name: Beijing Tongren Hospital name: Civil Aviation General Hospital name: Peking University Shougang Hospital name: The First Affiliated Hospital of Anhui Medical University name: Chinese PLA Central Hospital briefSummary: The goal of this multi-center, pragmatic, randomized controlled trial is to assess the effectiveness of continuous glucose monitoring (CGM) compared with conventional monitoring in enhancing surgical outcomes for diabetic patients. The main questions it aims to answer are:
The investigators will compare conventional monitoring group to see if CGM could reduce the CCIs for patients with diabetes or impaired glucose tolerance within 30 days after surgery. conditions: Comprehensive Complication Index studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 10168 type: ESTIMATED name: Continuous glucose monitoring (CGM) device measure: Comprehensive complication index measure: Postoperative complications measure: Morality measure: The length of the stay in the intensive care unit measure: The length of hospital stay measure: The overall hospitalization cost measure: Perioperative glucose level sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Zhifeng Gao status: RECRUITING city: Beijing state: Beijing zip: 102218 country: China name: Zhifeng Gao, MD role: CONTACT phone: 18756235568 email: btchgzf@hotmail.com lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06331910 id: TITNCUES briefTitle: Efficacy and Safety of Topical Insulin for Neurotrophic Corneal Ulcers overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-04-01 date: 2025-05-01 date: 2024-03-26 date: 2024-03-26 name: Assiut University class: OTHER briefSummary: To evaluate Safety and efficacy of topical insulin in treatment of neurotrophic corneal ulcers conditions: Neurotrophic Keratopathy studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 14 type: ESTIMATED name: insulin eye drops measure: Decrease in ulcer size and the increase in visual acuity . sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT hasResults: False
nctId: NCT06331897 id: Bronchial asthma briefTitle: Bronchial Asthma & Its Exacerbation overallStatus: NOT_YET_RECRUITING date: 2025-01-01 date: 2026-01-01 date: 2026-06-01 date: 2024-03-26 date: 2024-03-26 name: Assiut University class: OTHER briefSummary: Our goals is to assess :
1¬_ the role of spirometer in case of asthma exacerbation 2_hematological parameters (N/L ratio \& platelet indices \&CRP )in asthma exacerbation for diagnosing and classifying asthma severity and its exacerbation conditions: Bronchial Asthma studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 50 type: ESTIMATED measure: Assessment of Broncial asthma & its exacerbation : the utility of laboratory investigation , chest imaging , pulmonary function tests sex: ALL minimumAge: 2 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT hasResults: False
nctId: NCT06331884 id: PCZ_Phase1 briefTitle: Phase 1 Study to Evaluate Safety, Tolerability and Pharmacokinetics/-Dynamics of AK1967 (Procizumab) overallStatus: RECRUITING date: 2024-03-07 date: 2024-07-31 date: 2024-07-31 date: 2024-03-26 date: 2024-03-26 name: 4TEEN4 Pharmaceuticals GmbH class: INDUSTRY briefSummary: Dipeptidyl peptidase 3 (DPP3) is a protease involved in the degradation of several cardiovascular mediators. During cardiogenic shock, upregulation of the vasoconstrictive molecule angiotensin II is a physiologic and potentially life-saving response aimed at maintaining adequate tissue perfusion. As circulating (c)DPP3 is able to effectively cleave angiotensin II, it may represent a novel factor contributing to hemodynamic instability during cardiogenic shock.
Recently, a cDPP3-antagonizing antibody called AK1967 (commonly referred to as Procizumab) has been developed. In animal models of cardiogenic- and septic shock, inhibition of cDPP3 by AK1967 resulted in improved cardiac function and survival. Furthermore, AK1967 has shown an excellent safety record in different preclinical studies. In the current study the safety, tolerability and pharmacokinetics/-dynamics of AK1967 will be investigated in healthy male subjects. conditions: Safety and Tolerability studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 24 type: ESTIMATED name: AK1967 (Procizumab) name: Placebo measure: Reported number of adverse events from baseline (start of Procizumab administration) up until the last follow-up visit after Procizumab administration sex: MALE minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: Radboud University Medical Center status: RECRUITING city: Nijmegen state: Gelderland zip: 6525 country: Netherlands name: Peter Pickkers, MD, PhD role: CONTACT lat: 51.8425 lon: 5.85278 hasResults: False
nctId: NCT06331871 id: 2004202111621 briefTitle: Effectiveness of US-PENS for Patients With Post-surgical Shoulder Pain overallStatus: RECRUITING date: 2024-02-01 date: 2025-10-30 date: 2025-10-30 date: 2024-03-26 date: 2024-03-26 name: Universidad Rey Juan Carlos class: OTHER briefSummary: The aim of this clinical trial was to demonstrate the effectiveness of the application of ultrasound-guided percutaneous nerve stimulation (US-PENS) directed at the axillary nerve and the suprascapular nerve, in patients with post-surgical shoulder pain.
The intervention and follow-up period of the participants took place over 12 weeks. conditions: Ultrasound-Guided Percutaneous Electrical Nerve Stimulation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: 70 patients with shoulder pain undergoing arthroscopic surgery were recruited. They were divided into two groups at random; physiotherapy protocol group (n=35) and experimental group to which the same protocol was practiced and two sessions of ultrasound-guided percutaneous nerve stimulation (US-PENS) were added (n=35). primaryPurpose: TREATMENT masking: NONE count: 70 type: ESTIMATED name: Ultrasound Guied Percutaneus Electrical Nerve Stimulation (US-PENS) and Manual physiotherapy protocol based on available evidence. name: Manual physiotherapy protocol based on available evidence. measure: The Numeric Pain Rating Scale (NPRS) measure: Disabilities of the Arm, Shoulder and Hand (DASH) measure: The Shoulder Pain and Disability Index (SPADI) measure: GONIOMETRY measure: DINAMOMETRY measure: PAIN THRESHOLD ON PRESSURE sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Clinica Cemtro status: RECRUITING city: Madrid zip: 28049 country: Spain name: MARIO J ABRIL SERVÁN role: CONTACT phone: +34636707810 email: MASERVAN@HOTMAIL.COM name: FERNANDO GARCÍA SANZ role: CONTACT phone: +34917355757 email: fisioterapiaclub@clinicacemtro.com name: MARIO J ABRIL SERVÁN role: PRINCIPAL_INVESTIGATOR name: ADRIÁN CASES role: SUB_INVESTIGATOR lat: 40.4165 lon: -3.70256 hasResults: False
nctId: NCT06331858 id: KutahyaHSU-DRGOKPINARDROMER-43 briefTitle: The Effect of Adding Instrumented Hip Concentric Abductor Strengthening Exercise in Knee Osteoarthritis overallStatus: RECRUITING date: 2023-09-20 date: 2024-03-29 date: 2024-03-29 date: 2024-03-26 date: 2024-03-26 name: Kutahya Health Sciences University class: OTHER briefSummary: The aim of this study was to investigate the effectiveness of adding hip device-assisted concentric abductor strengthening (HDACAS) program to knee device-assisted concentric flexor-extensor strengthening (KDACFES) program on pain, function, physical performance, quality of life and gait parameters in patients with knee osteoarthritis (OA). conditions: Knee Osteoarthritis conditions: Pain conditions: Physical Disability studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: 1. STUDY GROUP
2. CONTROL GROUP primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Before and after the treatment, all patients were evaluated by a blind evaluator in terms of physical examination, pain and functionality, physical performance, quality of life and gait parameters. whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: hip device-assisted concentric abductor strengthening (HDACAS) name: knee device-assisted concentric flexor-extensor strengthening (KDACFES) measure: Western Ontario and McMaster Universities (WOMAC) measure: The Lequesne Algofunctional index measure: TIME UP AND GO TEST measure: 30 SECOND CHAIR TEST measure: 40 METER SELF PACED WALK TEST measure: SIX MINUTES WALK TEST measure: STAIR CLIMB TEST measure: Visual Analog Scale (VAS) measure: Mini Osteoarthritis Knee and Hip Quality of Life Scale sex: ALL minimumAge: 45 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Kutahya Health Sciences University status: RECRUITING city: Kutahya zip: 43100 country: Turkey name: Hasan Huseyin Gokpinar, Ass. Prof. role: CONTACT phone: +905052842222 email: hasanhuseyin.gokpinar@ksbu.edu.tr name: Ömer Özyümlü role: CONTACT phone: +905442024671 email: omer.ozyumlu@gmail.com lat: 39.42417 lon: 29.98333 facility: Kutahya Health Sciences University status: RECRUITING city: Kutahya zip: 43100 country: Turkey name: Hasan Huseyin Gokpinar, Ass. Prof. role: CONTACT phone: +905052842222 email: hasanhuseyin.gokpinar@ksbu.edu.tr lat: 39.42417 lon: 29.98333 hasResults: False
nctId: NCT06331845 id: NPC012 briefTitle: Stop and go Strategy as First-line Treatment for Widely Metastatic Nasopharyngeal Carcinoma overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-05-01 date: 2028-05-01 date: 2024-03-26 date: 2024-03-26 name: Fujian Cancer Hospital class: OTHER_GOV briefSummary: This study aimed to investigate the value of a novel strategy of intermittent systematic chemotherapy (ISC) in widely metastatic nasopharyngeal carcinoma (wmNPC) patients who achieve objective response after systematic chemotherapy (SC). conditions: Metastatic Nasopharyngeal Carcinoma conditions: Intermittent Systematic Chemotherapy studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 39 type: ESTIMATED name: Gemcitabine name: Cisplatin name: Paclitaxel protein-bound name: Capecitabine name: Tislelizumab measure: progression-free survival measure: progression-free survival 2 measure: overall survival sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06331832 id: 2323-EAP id: 2021-002339-44 type: EUDRACT_NUMBER briefTitle: Expanded Access of Imvotamab (IGM-2323) in Patients With R/R NHL overallStatus: NO_LONGER_AVAILABLE date: 2024-03-26 date: 2024-03-26 name: IGM Biosciences, Inc. class: INDUSTRY briefSummary: Expanded Access of Imvotamab (IGM-2323) in Patients with Relapsed/Refractory Non-Hodgkin Lymphomas from IGM-2323-001 clinical trial. conditions: Relapsed/Refractory Non-Hodgkin Lymphomas studyType: EXPANDED_ACCESS name: IGM2323 sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sir Charles Gairdner Hospital city: Nedlands state: Western Australia country: Australia lat: -31.98184 lon: 115.8073 facility: Samsung Medical Center city: Seoul state: Gangnam-gu country: Korea, Republic of lat: 37.566 lon: 126.9784 facility: START-Madrid Centro Integral Oncologico Clara Campal city: Madrid country: Spain lat: 40.4165 lon: -3.70256 hasResults: False
nctId: NCT06331819 id: 7-3-2024 briefTitle: Clinical Association Between Obstructive Sleep Apnea, Facial Pigmentation, and Vasovagal Symptoms. acronym: VasOSA overallStatus: RECRUITING date: 2024-03-10 date: 2025-01-01 date: 2025-03-01 date: 2024-03-26 date: 2024-03-26 name: Jordan Collaborating Cardiology Group class: OTHER briefSummary: The goal of this prospective cohort study is to study patients referred for sleep study by in-lab polysomnography in the Jordan University Hospital and the Jordan Hospital. The main aims are: