hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06269588 id: NBM-NP004 briefTitle: Efficacy and Safety of Nexpowder™ for Non-variceal, Upper Gastrointestinal Bleeding overallStatus: RECRUITING date: 2024-02 date: 2024-12 date: 2024-12 date: 2024-02-21 date: 2024-02-21 name: Changi General Hospital class: OTHER name: Next Biomedical Co., Ltd. name: Tan Tock Seng Hospital name: National University Hospital, Singapore briefSummary: The purpose of this pilot clinical trial is to confirm the efficacy and safety of Nexpowder™ for hemostasis in pilot cohort of patients with NVUGIB in Singapore conditions: Gastrointestinal Hemorrhage conditions: Hematemesis; With Ulcer conditions: Endoscopy studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: prospective single arm intervention cohort primaryPurpose: TREATMENT masking: NONE count: 24 type: ESTIMATED name: Nexpowder measure: endoscopic hemostasis measure: recurrent bleeding rate on second-look endoscopy measure: hydrogel persistence rate at the bleeding site measure: Recurrent bleeding within 30 days after endoscopic therapy sex: ALL minimumAge: 21 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Changi General Hospital status: RECRUITING city: Singapore zip: 529889 country: Singapore name: Tiing Ang, MRCP (UK) role: CONTACT phone: 69365737 email: ang.tiing.leong@singhealth.com.sg lat: 1.28967 lon: 103.85007 hasResults: False
nctId: NCT06269575 id: Dysphagia briefTitle: Evaluation Of The Effectiveness Of Safe Nutrition Program Applied To Acute Stroke Patients With Dysphagia overallStatus: COMPLETED date: 2020-10-05 date: 2023-08-15 date: 2023-12-15 date: 2024-02-21 date: 2024-02-21 name: Istanbul University - Cerrahpasa (IUC) class: OTHER briefSummary: It was planned in a quasi-experimental design with a non-randomized control group. The study was planned to be completed in three stages: control, preparation and intervention periods.
Question 1: Does a safe nutrition program prevent aspiration pneumonia, dehydration and malnutrition in acute stroke patients with dysphagia? Question 2: Is the safe nutrition program effective on addiction level, quality of life and depression in acute stroke patients with dysphagia? Question 3: Does a safe nutrition program shorten the hospital stay and NG tube duration in acute stroke patients with dysphagia? conditions: DYSPHAGIA studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: non-randomized controlled primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 78 type: ACTUAL name: SAFE NUTRITION PROGRAM measure: Complications of dysphagia measure: Complications of dysphagia measure: Complications of dysphagia measure: Stroke-Specific Quality of Life Scale (SS-QOL) measure: Swallowing Anxiety Scale (YKÖ) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Istanbul Universitesi-Cerrahpasa city: Istanbul country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06269562 id: clavicle briefTitle: SPSIPB and CPB on Clavicle Surgeries overallStatus: COMPLETED date: 2023-06-20 date: 2023-12-20 date: 2024-02-04 date: 2024-02-21 date: 2024-02-21 name: Cumhuriyet University class: OTHER briefSummary: Clavicular fractures represent a common occurrence often necessitating effective pain management strategies, particularly following surgical interventions. This study involved a cohort of five patients who underwent clavicular fracture surgery under general anesthesia. A novel analgesic approach combining two distinct nerve block techniques-Serratus Posterior Superior Intercostal Plane Block (SPSIPB) and Clavipectoral Plane Block (CPB)-was employed for postoperative pain control. The procedural methodology encompassed the administration of SPSIPB preceding anesthesia induction, followed by CPB subsequent to induction. SPSIPB targeted specific neural regions responsible for sensory blockade within the innervation of the clavicular skin, whereas CPB focused on the clavipectoral fascia. Standard anesthesia protocols were utilized, and postoperative pain levels were evaluated using Numeric Rating Scores (NRS). conditions: Clavicle Fracture conditions: Postoperative Pain conditions: Analgesia studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 5 type: ACTUAL name: Serratus posterior superior intercostal plane block and clavipectoral plane block measure: Numerical Rating Scale measure: tramadol consumption sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Sivas Cumhuriyet University city: Sivas zip: 58050 country: Turkey lat: 39.74833 lon: 37.01611 hasResults: False
nctId: NCT06269549 id: KDS_KOA briefTitle: Kinesiological / Dietary Supplement Intervention in Knee Osteoarthritis acronym: KDSKOA overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-09-30 date: 2025-12-31 date: 2024-02-21 date: 2024-02-26 name: University of Primorska class: OTHER name: Community Healthcare Center dr. Adolf Drolc Maribor (HCM) briefSummary: The goal of this clinical trial is to assess the effectiveness of dietary supplement combined with exercise in managing knee osteoarthritis (KOA). The main questions it aims to answer are:
nctId: NCT06269536 id: UC-SK004 briefTitle: Stress-reducing Intervention in Urothelial Carcinoma overallStatus: RECRUITING date: 2024-02-15 date: 2027-02-15 date: 2029-02-15 date: 2024-02-21 date: 2024-02-21 name: Comenius University class: OTHER briefSummary: The aim of this interventional study is to test the heart-rate variability biofeedback intervention (HRV BI) in patients with muscle-infiltrating bladder carcinoma (MIBC) treated with chemotherapy based on cisplatin in neoadjuvant setting followed by local therapy (standard of care, SOC) compared to SOC alone. conditions: Bladder Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 50 type: ESTIMATED name: HRV biofeedback measure: Primary Objective: Inflammation measure: Primary Objective: Heart Rate Variability (HRV) measure: Primary Objective: Quality of Life (QoL) measure: Primary Objective: Working memory measure: Primary objective: Executive function measure: Primary objective: Salivary Cortisol Slopes measure: Primary objective: Sleep Quality measure: Secondary objective: Serious Adverse Events measure: Secondary objective: Disease-Free Survival (DFS) measure: Secondary objective: Overall Survival (OS) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: National Cancer Institute status: RECRUITING city: Bratislava zip: 83310 country: Slovakia name: Katarina Rejlekova role: CONTACT email: katarina.rejlekova@nou.sk name: Patrik Palacka role: PRINCIPAL_INVESTIGATOR lat: 48.14816 lon: 17.10674 hasResults: False
nctId: NCT06269523 id: MFR032024 briefTitle: Effects of Rehabilitation and Kinesio Taping to Prevent Axillary Web Syndrome After Breast Cancer Surgery overallStatus: COMPLETED date: 2021-07-21 date: 2023-01-31 date: 2024-01-31 date: 2024-02-21 date: 2024-02-21 name: University of Palermo class: OTHER briefSummary: Axillary web syndrome (AWS) is a complication associated with breast cancer surgery, characterized by pain, functional limitation of the shoulder and decreased quality of life. There are several physical treatment options to reduce pain and improve the functionality of the upper limb in women with AWS. This study evaluates the effectiveness of an early rehabilitation approach to prevent axillary web syndrome consisting in functional and proprioceptive re-education, manual lymphatic drainage and kinesio taping after breast cancer surgery. conditions: Axillary Web Syndrome studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 18 type: ACTUAL name: Kinesio taping, Lymphatic drainage name: Lymphatic drainage measure: NRS Scale measure: Joint excursion shoulder measure: Muscular strength of the upper limbs measure: Constant Murley Score measure: upper limbs circumferenze (cyrtometry) sex: FEMALE minimumAge: 45 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Functional Recovery and Rehabilitation Unit of the A.O.U.P. Paolo Giaccone city: Palermo zip: 90127 country: Italy lat: 38.13205 lon: 13.33561 hasResults: False
nctId: NCT06269510 id: HUM00242997 id: 1R01AA030748-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R01AA030748-01 briefTitle: Enhancing Alcohol Treatment Engagement in Associated Liver Disease (ALD) Patients overallStatus: NOT_YET_RECRUITING date: 2025-04 date: 2027-07 date: 2027-07 date: 2024-02-21 date: 2024-03-26 name: University of Michigan class: OTHER name: National Institute on Alcohol Abuse and Alcoholism (NIAAA) briefSummary: The purpose of this trial is to see if providing patients with alcohol-related liver disease with tailored alcohol use treatment options will increase engagement with treatment and correct possible misconceptions. conditions: Alcohol-related Liver Disease conditions: Liver Diseases studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: Computer-generated urn randomization will ensure balanced groups based on stage of ALD (advanced ALD and non-advanced ALD) and inpatient versus outpatient status at time of recruitment. Second stage randomization to 3-month intervention conditions will be stratified based on response and non-response status. Urn randomization using stage of ALD and inpatient versus outpatient recruitment will also be used at the second stage randomization. Re-randomization of non-responders will be computerized and stratified by stage of ALD and inpatient vs outpatient status. primaryPurpose: TREATMENT masking: NONE count: 268 type: ESTIMATED name: ENGAGE-ALD Application (APP) name: Treatment Facilitation bundle name: Enhanced Usual Care measure: Alcohol treatment engagement measure: Alcohol Use Frequency as Measured by a 30-day alcohol recall calendar method measure: Percent heavy drinking days (PHDD) measure: Change in Liver health based on liver laboratory values (aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase) for all participants measure: Change in Liver health based on liver laboratory values (total bilirubin) for all participants measure: Change in Liver health based on The Model for End-Stage Liver Disease (MELD) score in participants with cirrhosis or alcoholic hepatitis sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Michigan city: Ann Arbor state: Michigan zip: 48109 country: United States name: Haila Asefa role: CONTACT phone: 734-232-0284 email: asefah@umich.edu name: Jessica Mellinger, MD, MSc role: PRINCIPAL_INVESTIGATOR lat: 42.27756 lon: -83.74088 hasResults: False
nctId: NCT06269497 id: 2018/2300 briefTitle: TiO2-scaffolds for Alveolar Ridge Preservation acronym: TIOSCAFF overallStatus: COMPLETED date: 2021-11-09 date: 2022-06-20 date: 2023-08-10 date: 2024-02-21 date: 2024-02-21 name: University of Oslo class: OTHER briefSummary: The goal of this clinical trial is to evaluate the safety of placing TiO2 scaffolds in alveolar ridge and to evaluate if the scaffold material contributes to maintain the anatomy and the volume of the alveolar process after tooth extraction. conditions: Alveolar Bone Resorption studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Observational study / clinical trial primaryPurpose: OTHER masking: NONE count: 10 type: ACTUAL name: Scaffold placement name: CBCT measure: Adverse reactions measure: Anatomy measure: Inflammation measure: Mineralization sex: ALL minimumAge: 20 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Faculty of Dentistry, University of Oslo city: Oslo zip: Postboks 1142 Blindern country: Norway lat: 59.91273 lon: 10.74609 hasResults: False
nctId: NCT06269471 id: 2023-A02039-36 briefTitle: On the ICC's Path: a Prevalence Study acronym: SSICC overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-05-30 date: 2024-07-30 date: 2024-02-21 date: 2024-02-21 name: University Hospital, Grenoble class: OTHER briefSummary: The number of trailers is growing all the time, and TRu seems to be a risky activity for the ankle joint. Ankle sprains can lead to significant health consequences, as in the case of chronic ankle instability.
However, there are no studies informing of the prevalence of chronic ankle instability in trail running. The aim of this study is therefore to take stock of chronic ankle instability in trail running in France. conditions: Chronic Ankle Instability studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 385 type: ESTIMATED measure: Prevalence of chronic ankle instability in trailers measure: Socio-demographic data (1/4) measure: Socio-demographic data (2/4) measure: Socio-demographic data (3/4) measure: Socio-demographic data (4/4) measure: Trail running and prevalence reports (1/11) measure: Trail running and prevalence reports (2/11) measure: Trail running and prevalence reports (3/11) measure: Trail running and prevalence reports (4/11) measure: Trail running and prevalence reports (5/11) measure: Trail running and prevalence reports (6/11) measure: Trail running and prevalence reports (7/11) measure: Trail running and prevalence reports (8/11) measure: Trail running and prevalence reports (9/11) measure: Trail running and prevalence reports (10/11) measure: Trail running and prevalence reports (11/11) measure: Associated pathologies (1/2) measure: Associated pathologies (2/2) measure: Medical care (1/3) measure: Medical care (2/3) measure: Medical care (3/3) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University Grenoble Alpes city: Grenoble zip: 38000 country: France name: Leo Druart role: CONTACT email: leo.druart@univ-grenoble-alpes.fr name: Audrey Milon role: PRINCIPAL_INVESTIGATOR name: Massamba M'Baye role: SUB_INVESTIGATOR name: Thomas Lathière role: SUB_INVESTIGATOR name: Maïa Dolopogoloff role: SUB_INVESTIGATOR name: Guillaume Néron role: SUB_INVESTIGATOR lat: 45.16667 lon: 5.71667 hasResults: False
nctId: NCT06269458 id: ABU-001 briefTitle: The Effects of Mother-Baby Yoga and Baby Massage on Attachment and Sleep overallStatus: COMPLETED date: 2023-01-01 date: 2023-11-25 date: 2023-12-26 date: 2024-02-21 date: 2024-02-21 name: Antalya Bilim University class: OTHER briefSummary: Purpose: This study was conducted to examine the effects of mother-baby yoga and massage on mother-baby bonding and the baby's sleep.
Method: A randomised, crossover pilot study was conducted in the postpartum service of a hospital between January and November 2023, with 60 mothers and their babies in the postpartum period, 30 in each group. To the mothers and their babies included in the research, baby massage was applied to one group and mother-baby yoga was applied to the other. After four weeks, the groups' practices were changed. In the results of the research, characteristics related to attachment and sleep were evaluated. conditions: Newborn conditions: Yoga conditions: Mother-Infant Interaction conditions: Sleep studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 60 type: ACTUAL name: Baby Massage name: Monther-Baby Yoga measure: Attachment measure: Weight and Sleep sex: ALL minimumAge: 0 Days maximumAge: 5 Days stdAges: CHILD facility: Antalya Bilim Üniversitesi city: Antalya country: Turkey lat: 36.90812 lon: 30.69556 hasResults: False
nctId: NCT06269445 id: 2023-942-01 briefTitle: The Efficacy and Safety of Lcaritin Combined With Bevacizumab and FOLFIRI in Treatment of Liver Metastases From Colorectal Cancer overallStatus: RECRUITING date: 2024-01-01 date: 2025-02-01 date: 2026-02-01 date: 2024-02-21 date: 2024-02-21 name: Sir Run Run Shaw Hospital class: OTHER briefSummary: To evaluate the efficacy and safety of the combination regimen of Icaritin with bevacizumab + FOLFIRI in patients with liver metastases from advanced colorectal cancer. conditions: Colorectal Cancer studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 20 type: ESTIMATED name: Icaritin Combined With Bevacizumab and FOLFIRI measure: Progression-free survival(PFS) measure: Objective remission rate (ORR) measure: Overall survival (OS) measure: Disease Control Rate (DCR) measure: Duration of ongoing remission (DOR) measure: TRAEs measure: Quality of life of the patients sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sir Run Run Shaw Hospital, Zhejiang University School of Medicine status: RECRUITING city: Hangzhou state: Zhejiang zip: 310000 country: China name: Fei Wang role: CONTACT phone: 13732236150 email: 21418531@zju.edu.cn lat: 30.29365 lon: 120.16142 hasResults: False
nctId: NCT06269432 id: 2023YFS0042 briefTitle: Precise Antiplatelet THerapy Guided by Platelet Aggregation Function in Acute Ischemic STROKE（PATH-STROKE） acronym: PATH-STROKE overallStatus: RECRUITING date: 2023-01-01 date: 2025-12-31 date: 2025-12-31 date: 2024-02-21 date: 2024-02-21 name: Sichuan Provincial People's Hospital class: OTHER briefSummary: Objectives of Study:To explore the efficacy and safety of antiplatelet therapy in patients with non-cardiogenic cerebral infarction under the guidance of platelet aggregation function. conditions: Ischemic Stroke conditions: Antiplatelet Drug studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 3524 type: ESTIMATED name: Precision Antiplatelet Therapy Trial Group name: Traditional Antiplatelet Therapy Control Group measure: 3-month major ischemic events and major bleeding events measure: disability measure: Cardiovascular or cerebrovascular mortality sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sichuan Provincial People's Hospital status: RECRUITING city: Chengdu state: Sichuan zip: 610072 country: China name: Jie Yang, doctor role: CONTACT phone: +86 13678130516 email: yangjie1126@163.com lat: 30.66667 lon: 104.06667 hasResults: False
nctId: NCT06269419 id: 2023-KY295 briefTitle: Study of Natural Course Progression of Diabetic Retinopathy overallStatus: RECRUITING date: 2024-02-25 date: 2029-01-01 date: 2029-01-01 date: 2024-02-21 date: 2024-03-12 name: Jie Li class: OTHER briefSummary: The goal of this observational study is to observe the formation and development of the non-perfusion area of diabetic retinopathy in the posterior area of the retina in type 2 diabetes patients aged 18-75 years old, who can cooperate with all examinations and sign informed consent, clinical myopathy examination and Optos 7 field of vision with mild than severe NPDR, and no other exclusion indicators.The main questions it aims to answer are whether posterior retinal non-perfusion area occurs earlier than peripheral non-perfusion area and whether the rate of non-perfusion area expansion is a risk factor for the progression of diabetic retinopathy.
Best corrected vision, logarithmic visual acuity chart. Tupai OCTA, 24×20mm range, 6×6mm range scan. Optos fundus imaging, color and no red light images. Fundus fluorescence angiography (only preliminary examination for the first time found mild to moderate NPDR patients, who have been angiographed in the past, only at the 5th year, or as required by the condition).
Urinary microalbumin/urinary creatinine ACR. Microvisual field. conditions: Biomarkers of Diabetic Retinopathy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 200 type: ESTIMATED measure: Observation and follow-up of biomarkers of diabetic retinopathy measure: Level of Glycosylated hemoglobin measure: Creatinine measure: Total cholesterol measure: Urinary microalbumin measure: Urea measure: Glomerular filtration rate measure: Triglycerides measure: Low-density lipoprotein cholesterol measure: High-density lipoprotein cholesterol measure: Urinary creatinine ACR sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sichuan Academy of Medical Science Sichuan Provincial Hosptial status: RECRUITING city: Chendu state: Sichuan zip: 610014 country: China name: Jie Li, doctor role: CONTACT phone: +86 13908094675 email: lijieyk@med.uestc.edu.cn hasResults: False
nctId: NCT06269406 id: SW008 briefTitle: A Combination of Ibuprofen With Curcumin Covered With Liquorice Root Supplementation in the Management of Postoperative Dental Pain in Adults acronym: ICLID overallStatus: NOT_YET_RECRUITING date: 2024-03-10 date: 2024-07-10 date: 2024-09-10 date: 2024-02-21 date: 2024-02-21 name: S.LAB (SOLOWAYS) class: OTHER name: NMSI DENTMASTER briefSummary: Dental pain, a common issue in stomatology, requires a multifaceted treatment approach. This study explores the efficacy of combining Ibuprofen with curcumin and liquorice root supplements for managing postoperative dental pain. Curcumin, known for its antioxidant and anti-inflammatory properties, along with liquorice root, may enhance pain relief beyond conventional NSAIDs like Ibuprofen. This randomized, double-blind, placebo-controlled trial aims to evaluate the safety and effectiveness of this combination therapy in adults undergoing the removal of impacted third molars. Participants, aged 18-85, were divided into groups receiving different doses of Ibuprofen and curcumin with liquorice root, compared to a control group receiving Ibuprofen and placebo. The primary outcome is the sum of pain intensity differences over 8 hours, with secondary outcomes including total pain relief and the occurrence of any adverse events. The anticipated sample size, considering a 20% dropout rate, is 264 participants, ensuring the study is powered to detect significant differences in pain management efficacy. conditions: Dental Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 264 type: ESTIMATED name: ibuprofen 400 mg in combination with Curcumin covered with liquorice root 100 mg name: ibuprofen 200 mg in combination with Curcumin covered with liquorice root 100 mg name: The combination of ibuprofen 400 mg and placebo in patients after 2-4 molars procedure measure: Sum of pain intensity differences (SPID), SPID on the visual analog score VAS (points) measure: Total pain relief (TOTPAR) % measure: Time to pain half pain gone (in minutes) measure: Duration of pain half gone (in minutes) measure: Any adverse events (facial swelling, nausea, vomiting, headache) (%) sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Nmsi Dentmaster city: Novosibirsk state: Novosibirsk Region zip: 630090 country: Russian Federation name: Gatilova A Tatyana, MD role: CONTACT phone: 9529399919 phoneExt: +7 lat: 55.0415 lon: 82.9346 hasResults: False