hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06355882 id: LCOSDental briefTitle: Patients With Low Cardiac Output Syndrome Undergoing Local Dental Anesthesia overallStatus: RECRUITING date: 2023-08-08 date: 2024-12-01 date: 2024-12-01 date: 2024-04-10 date: 2024-04-22 name: University of Sao Paulo General Hospital class: OTHER name: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior. briefSummary: Patients with low cardiac output syndrome requiring surgical and periodontal dental treatment will be selected to undergo the dental procedure using local dental anesthetic: 2% lidocaine with epinephrine and 2% lidocaine without vasoconstrictor. Cardiovascular events and the safety of using two cartridges (3.6 mL) will be evaluated. They will be evaluated by Holter monitoring in the period of 1 hour before, during and 1 hour after the procedure and blood pressure correction will be performed conditions: Low Cardiac Output Syndrome studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 29 type: ESTIMATED name: Anesthetic infiltration measure: Amount ventricular and supraventricular arrhythmia sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Instituto do Coração HCFMUSP status: RECRUITING city: São Paulo zip: 05403000 country: Brazil name: Itamara LI Neves, PhD role: CONTACT phone: 1126615229 email: itamara@incor.usp.br name: Mariana DC Dias role: CONTACT phone: 19996614440 email: mariana2497@gmail.com name: Itamara LI Neves, PhD role: PRINCIPAL_INVESTIGATOR lat: -23.5475 lon: -46.63611 hasResults: False
nctId: NCT06355869 id: s65337 briefTitle: Repeatability of Gait Deviations in Children With Cerebral Palsy overallStatus: COMPLETED date: 2021-08-17 date: 2023-05-31 date: 2023-05-31 date: 2024-04-10 date: 2024-04-15 name: Universitaire Ziekenhuizen KU Leuven class: OTHER briefSummary: Three-dimensional gait analysis (3DGA) is the 'gold standard' for measurement and description of gait. Gait variability can arise from intrinsic and extrinsic factors and may vary between walking conditions. This study aimed to define the inter-trial (intrinsic) and inter-session (extrinsic) repeatability in gait analysis data of children with CP who were walking in four conditions, namely barefoot or with ankle-foot orthosis, and overground or treadmill. conditions: Spastic Cerebral Palsy studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 10 type: ACTUAL name: repeated 3D gait-analysis measure: The standard error of measurement (SEM) of the continuous kinematic gait waveforms measure: The intra-class correlation (ICC) of the gait indices measure: The standard error of measurement (SEM) of the continuous kinetic gait waveforms measure: The standard error of measurement (SEM) of the gait indices sex: ALL minimumAge: 6 Years maximumAge: 17 Years stdAges: CHILD facility: UZ Leuven city: Leuven state: Vlaams-Brabant zip: 3000 country: Belgium lat: 50.87959 lon: 4.70093 hasResults: False
nctId: NCT06355856 id: ACH-PNT-04(01/22) briefTitle: Efficacy/ Safety of DNN.22.17.036 in Male Patients With Pattern Hair Loss acronym: CAPELLI overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-05 date: 2025-05 date: 2024-04-10 date: 2024-04-10 name: Ache Laboratorios Farmaceuticos S.A. class: INDUSTRY briefSummary: Evaluation of the efficacy and safety of DNN.22.17.036 versus 10573048700 in the treatment of male pattern hair loss. conditions: Alopecia studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 196 type: ESTIMATED name: DNN.22.17.036 name: 10573048700 measure: Percentage variation of hairs in the hair loss phase sex: MALE minimumAge: 25 Years maximumAge: 60 Years stdAges: ADULT hasResults: False
nctId: NCT06355843 id: SXY briefTitle: Clinical Applications of Integrated PET/MR and PET/CT in the Diagnosis and Treatment of Prostate Cancer. overallStatus: SUSPENDED date: 2022-04-28 date: 2023-09-30 date: 2027-03-31 date: 2024-04-09 date: 2024-04-09 name: The First Affiliated Hospital of Anhui Medical University class: OTHER name: National Natural Science Foundation of China briefSummary: The goal of this study type: observational study (prospective study) is to study prostate cancer occurrence and recurrence, to specifically identify and localize tumor foci at the molecular level at an early stage, to evaluate the prognosis of patients, and to accurately stage not only intermediate- and high-risk prostate cancer patients with a primary diagnosis, but also detect recurrent foci in patients with biochemical recurrence, to restage those who have developed metastases, to assess tumor load, and to ultimately assist in determining the personalized treatment plans. The main question it aims to answer is whether 68Ga-PSMA PET/CT (PET/MR) examination is beneficial for assessing the
* Assessment of patient prognosis. Participants will sign an informed consent form, undergo 68Ga-PSMA PET/CT (PET/MR) before surgery or biopsy, and have regular follow-up after obtaining pathological results of surgical resection or puncture biopsy, 6 weeks after surgery or biopsy, and then every 3 months; the follow-up will include: blood PSA, whole-body bone imaging, etc. conditions: Prostate Cancer conditions: Pet-ct studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 50 type: ESTIMATED name: 68Ga-PSMA measure: Measuring the value of 68Ga-PSMA PET/MRI in the diagnosis and staging of primary prostate cancer and comparing it with mp-MRI and PET/CT measure: Exploring whether 68Ga-PSMA PET/MRI can be used as a method for diagnostic efficacy sex: MALE minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: First affiliated hospital of anhui university city: Hefei state: Anhui zip: 230032 country: China lat: 31.86389 lon: 117.28083 hasResults: False
nctId: NCT06355830 id: RETimaging4iAMD briefTitle: Intermediate Age-related Macular Degeneration - Multimodal Analysis and Longitudinal Study acronym: Imaging4iAMD overallStatus: RECRUITING date: 2019-01-02 date: 2025-06 date: 2026-06 date: 2024-04-09 date: 2024-04-09 name: Universidade Nova de Lisboa class: OTHER name: iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, UNL name: Centro Hospitalar de Lisboa Central EPE, Lisboa, Portugal name: Centro Hospitalar Universitário de São João, Porto, Portugal briefSummary: Study: observational prospective clinical study. Study population: Subjects over 55 years old with drusen secondary to intermediate AMD.
Primary outcome: Identifying imaging predictors of iAMD progression. conditions: Age-Related Macular Degeneration studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 150 type: ESTIMATED name: Orthoptic assessment (Outcome measure) measure: Change in incomplete retinal pigment epithelial and outer retinal atrophy (iRORA) from baseline measure: Change in Drusen morphology from baseline measure: Change in Subfoveal drusen area from baseline measure: Change in other drusen area from baseline measure: Change in Drusen reflectivity from baseline measure: Change in other Drusen homogeneity from baseline measure: Change in ellipsoid zone disruption from baseline measure: Change in Drusen homogeneity from baseline measure: Change in hyperreflective foci from baseline measure: Change in hyperreflective foci location (within 500-μm disc area) from baseline measure: Change in hyperreflective foci association to drusen from baseline measure: Progression to Moderate Vision Loss measure: Geographic Atrophy (GA) Growth Rate measure: Progression to Advanced AMD according to international classification/grading system sex: ALL minimumAge: 55 Years maximumAge: 95 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ophthalmology Service, Centro Hospitalar de Lisboa Central EPE status: RECRUITING city: Lisbon zip: 1150-199 country: Portugal name: Rita Flores, MD role: CONTACT phone: 00351218841000 phoneExt: 21355 email: ritamariaflores@gmail.com lat: 38.71667 lon: -9.13333 hasResults: False
nctId: NCT06355817 id: HS25941 briefTitle: Distraction Techniques in Periocular Anesthesia: Tapping vs Vibration overallStatus: COMPLETED date: 2023-09-21 date: 2024-03-19 date: 2024-03-19 date: 2024-04-09 date: 2024-04-22 name: University of Manitoba class: OTHER name: Winnipeg Regional Health Authority briefSummary: To compare the efficacy of topical tapping vs vibration in lowering pain scores for periocular anesthesia injections. conditions: Anesthetics, Local conditions: Blepharoplasty conditions: Age-Related Ptosis conditions: Adult conditions: Humans conditions: Lidocaine conditions: Ophthalmologic Surgical Procedure conditions: Vibration conditions: Surgery studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Each patient will receive both interventions and serve as their own comparator. primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: The participant and surgeon was not made aware of which intervention the participant would receive first until the time of the procedure. Randomization was made at the time of the procedure. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 80 type: ACTUAL name: Vibration name: Tapping measure: Pain Reduction in Tapping vs Vibration distraction techniques in peri-ocular local anesthesia measure: Difference in Pain Reduction sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Misericordia Health Centre city: Winnipeg state: Manitoba zip: R3C 1A2 country: Canada lat: 49.8844 lon: -97.14704 hasResults: False
nctId: NCT06355804 id: STUDY2023-1565 briefTitle: Lifestyle Physical Activity Intervention for Persons Newly Diagnosed With Multiple Sclerosis overallStatus: NOT_YET_RECRUITING date: 2024-04-22 date: 2025-04-22 date: 2025-04-22 date: 2024-04-09 date: 2024-04-09 name: University of Illinois at Chicago class: OTHER briefSummary: The overall objective of the current study is to determine the efficacy of a 16-week remotely delivered lifestyle behavioral intervention compared with a control condition (i.e., waitlist control) in persons newly diagnosed with MS (disease duration ≤ 2 years).
Specific Aim 2: To investigate the efficacy of the 16-week, remotely delivered physical activity behavior change intervention compared with the control condition for improvements in fatigue, depression, anxiety, and QoL in persons newly diagnosed with MS. The investigators hypothesize that there will be beneficial effects on the symptoms and QoL outcomes immediately after the physical activity intervention compared with minimal changes in the control condition. conditions: Multiple Sclerosis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 50 type: ESTIMATED name: Physical activity condition name: Waitlist condition measure: Physical Activity Behavior measure: Physical Activity Behavior measure: Physical Activity Level (Light physical activity) measure: Physical Activity Level (Moderate-to-vigorous physical activity) measure: Physical Activity Level (Daily step count) measure: Health-related quality of Life measure: Health-related Quality of Life measure: Fatigue Severity measure: Depressive Symptoms measure: Anxiety sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06355791 id: PDPROJ-4-TP-001-23 briefTitle: The Stability Study acronym: STABILITY overallStatus: ENROLLING_BY_INVITATION date: 2024-04-15 date: 2025-04-30 date: 2025-09-30 date: 2024-04-09 date: 2024-04-09 name: Spinal Simplicity LLC class: INDUSTRY briefSummary: The studied indication is degenerative conditions of the lumbar spine resulting in back pain with lower extremity symptoms and neurogenic claudication.
The purpose of this study is to evaluate the effectiveness and safety of instrumented posterior arthrodesis using the Spinal Simplicity Minuteman G5 MIS Fusion Plate and bone graft material in patients with degenerative conditions of the lumbar spine resulting in chronic low back pain with lower extremity symptoms and concurrent neurogenic claudication. conditions: Lumbar Spinal Stenosis conditions: Spondylolisthesis studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 150 type: ESTIMATED name: Minuteman G5 measure: NRS Back and Leg measure: ODI measure: PROMIS 29 2.0 measure: 12 Month Fusion Assessment sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Kansas University Medical Center city: Kansas City state: Kansas zip: 66160 country: United States lat: 39.11417 lon: -94.62746 hasResults: False
nctId: NCT06355778 id: HUM00234185 id: 1R01DA056415 type: NIH link: https://reporter.nih.gov/quickSearch/1R01DA056415 briefTitle: Adversity, Brain and Opioid Use Study overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2028-04 date: 2028-04 date: 2024-04-09 date: 2024-04-09 name: University of Michigan class: OTHER name: National Institute on Drug Abuse (NIDA) briefSummary: The way people process and remember information may be related to adverse childhood experiences and Opioid Use Disorder symptoms. The purpose of this project is to examine brain function and performance during learning and memory tasks in adults. The study will compare measures of learning and memory across three groups of participants: those with an Opioid Use Disorder (OUD) that take buprenorphine for opioid replacement therapy, adults without an Opioid Use Disorder taking buprenorphine, and healthy adults that do not have an Opioid Use Disorder and are not taking buprenorphine. conditions: Opioid Use Disorder conditions: Healthy studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: NONE count: 315 type: ESTIMATED name: Magnetic Resonance Imaging (MRI) name: Computer Tasks measure: Differences in Blood Oxygen Level Dependent (BOLD) signal in the hippocampus measure: Differences in Hippocampal (Hpc) volume measure: Differences in hippocampal circuit connectivity measure: Differences in performance measure: Differences in performance measure: Differences in threat reactivity measured via skin conductance response (SCR) measure: Differences in threat reactivity measured via skin conductance response (SCR) sex: ALL minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: University of Michigan city: Ann Arbor state: Michigan zip: 48109 country: United States name: Mariya Churina role: CONTACT email: AdversityBrainOUD@med.umich.edu name: Elizabeth Duval, PhD role: PRINCIPAL_INVESTIGATOR lat: 42.27756 lon: -83.74088 hasResults: False
nctId: NCT06355765 id: CITIZ_001 briefTitle: Citicoline & Antioxidants in Glaucoma overallStatus: COMPLETED date: 2022-01-10 date: 2022-12-10 date: 2022-12-10 date: 2024-04-09 date: 2024-04-17 name: University of Naples class: OTHER briefSummary: To evaluate the long-term effects of oral citicoline, vitamins A, B, C and E, and blackcurrant therapy in patients with primary open-angle glaucoma (POAG) using optical coherence tomography (OCT), OCT angiography (OCTA) and microperimetry parameters. conditions: Glaucoma, Open-Angle studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 60 type: ACTUAL name: Citicoline blackcurrant supplement measure: Evaluation of Ganglionar cells complex (GCC) measure: Evaluation of Retinal nerve fiber layer (RNFL) sex: ALL minimumAge: 30 Years maximumAge: 90 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Naples Federico II city: NAples zip: 80131 country: Italy lat: 40.85216 lon: 14.26811 hasResults: False
nctId: NCT06355752 id: 0018-N-23 briefTitle: Biomarkers of Pain and Stress Perception and Dry Needling Technique Application overallStatus: RECRUITING date: 2024-04-12 date: 2024-07-15 date: 2024-07-15 date: 2024-04-09 date: 2024-04-16 name: University of Alcala class: OTHER briefSummary: The use of the dry needling technique has become widespread in recent years for the treatment of musculoskeletal pain. Although dry needling has been shown to be effective in the treatment of shoulder pain, elbow pain, headache, etc., we do not yet have a clear understanding of the mechanisms of action that justify its beneficial effects.
Another group will be treated with a sham technique. conditions: Low Back Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 36 type: ESTIMATED name: Dry needling of lumbar iliocostalis muscle name: Sham dry needling lumbar iliocostalis muscle measure: Extracting Blood Samples and Obtaining Serum/Plasma sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Centro Investigación Fisioterapia y Dolor status: RECRUITING city: Alcalá De Henares state: Madrid zip: 28805 country: Spain name: Patricia Martinez-Merinero, PhD role: CONTACT phone: 683378391 email: info@institutofisioterapiaydolor.es name: Laura Cabellos role: CONTACT phone: 683378391 email: clinica.fisio@fgua.es lat: 40.48205 lon: -3.35996 hasResults: False
nctId: NCT06355739 id: BIC-19GG, BIC-2019,BIC-2219 briefTitle: CD19-targeted CAR T Cell Autotransfusion for the Treatment of Recurrent/Refractory B-cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma in Children With CD19+ overallStatus: RECRUITING date: 2024-02-01 date: 2026-12-01 date: 2027-01-15 date: 2024-04-09 date: 2024-04-09 name: Zhu Xiaofan class: OTHER briefSummary: To evaluate the safety and efficacy of BIC-19GG, BIC-2019, BIC-2219 in the treatment of relapsed/refractory B acute lymphoblastic leukemia/lymphoblastic lymphoma in children conditions: B Lymphocytic Leukemia conditions: B Lymphoblastic Lymphoma studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 60 type: ESTIMATED name: CAR T cell injection measure: Overall survival and event-free survival measure: Overall remission rate measure: Adverse events sex: ALL minimumAge: 3 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Department of Pediatrics, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences status: RECRUITING city: Tianjin state: Tianjin zip: 300020 country: China name: Xiaofan Zhu, MD role: CONTACT phone: 86-21-23909001 email: xfzhu@ihcams.ac.cn name: Jingliao Zhang, MD role: SUB_INVESTIGATOR lat: 39.14222 lon: 117.17667 facility: InstituteHBDH status: NOT_YET_RECRUITING city: Tianjin state: Tianjin zip: 300020 country: China name: Zhu Xiaofan role: CONTACT phone: 86-21-23909001 email: xfzhu@ihcams.ac.cn name: Guo Ye role: PRINCIPAL_INVESTIGATOR name: Yang Wenyu role: PRINCIPAL_INVESTIGATOR name: Chen Xiaojuan role: PRINCIPAL_INVESTIGATOR name: Chen Yumei role: PRINCIPAL_INVESTIGATOR name: Ruan Min role: PRINCIPAL_INVESTIGATOR lat: 39.14222 lon: 117.17667 hasResults: False
nctId: NCT06355726 id: ILBS-Alcoholic Hepatitis-03 briefTitle: Efficacy of Plasma Exchange Therapy vs Standard Medical Therapy in Severe Alcoholic Hepatitis With High Discriminant Function overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-02-28 date: 2025-02-28 date: 2024-04-09 date: 2024-04-09 name: Institute of Liver and Biliary Sciences, India class: OTHER briefSummary: Alcoholic hepatitis, the most florid form of alcoholic liver disease, has a very high short-term mortality of up to 50% and no specific therapies are available other than steroids. Steroids also only show a limited utility in improving the short-term survival and boast no evidence of any long-term benefits. Additionally, only a small proportion of patients with alcoholic hepatitis are eligible to receive steroids. Thus, a large number of patients are either not eligible or do not respond to steroids and this group outnumbers those who do respond to steroids, leaving us without any specific therapeutic options for a majority of these individuals.\[1\] Even liver transplantation is not feasible in most cases due to the presence of sepsis or recent alcohol consumption and many ethical and logistic issues are involved despite the documented safety and survival benefits of early liver transplantation in patients with severe alcoholic hepatitis (SAH) not responding to medical management.\[2,8\] Therefore, newer, more effective, and nontransplant therapeutic options for managing severe alcoholic hepatitis are needed. TPE is expected to be an effective and well-tolerated bridge therapy in patients with severe alcoholic hepatitis of moderate severity not improving on SMT and without immediate prospects for liver transplantation. conditions: Alcoholic Hepatitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 60 type: ESTIMATED name: Plasma Exchange name: Standard Medical Treatment measure: Liver transplant free survival at 28 days, 90 days and 180 days. measure: Change in total bilirubin and INR as measured by Discriminant Functions measure: Number of patients with change in Model for End Stage Liver Disease (MELD) measure: Number of patients with change in CTP measure: Number of patients with change in LSM,SSM measure: Mortality in both groups measure: clinical improvement in the form of jaundice as measured by total bilirubin measure: clinical improvement in the form of hepatic encephalopathy as measured by west haven criteria measure: clinical improvement in the form of ascites as measured by ICA criteria. measure: Frequency of decompensation events on follow up period measure: Adverse events during plasma exchange sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Institute of Liver & Biliary Sciences (ILBS) city: New Delhi state: Delhi zip: 110070 country: India lat: 28.63576 lon: 77.22445 hasResults: False
nctId: NCT06355713 id: 69HCL23_0899 id: 2023-A02010-45 type: OTHER domain: ID-RCB briefTitle: Improvement of Symptoms After Removal of the Essure® Contraceptive Implant acronym: ABLES overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2031-08-01 date: 2036-06-01 date: 2024-04-09 date: 2024-04-09 name: Hospices Civils de Lyon class: OTHER briefSummary: ESSURE® is an implantable medical device for definitive and irreversible sterilization indicated for adult women of childbearing age. These implants are inserted into the fallopian tubes by hysteroscopy. Marketed in 2002, ESSURE® contraceptive implants were withdrawn from the French market in 2017 (and worldwide in 2017 and 2018) following the observation in certain patients of polymorphic and non-specific gynecological and extra-gynecological symptoms. Studies with small numbers and short-term follow-up have shown a significant improvement in these symptoms after implant explantation. This constitutes a real public health problem since according to the report of the EPI-PHARE Scientific Interest Group, 198,000 French women have these implants and only 30,000 of them, or 15%, have been explanted, knowing that explantation of ESSURE® implants is recommended only in symptomatic patients. A large number of these patients, presenting symptoms, have not yet been treated for an explant.
nctId: NCT06355700 id: 5476 briefTitle: Hepatocellular Carcinoma Liver Organoids acronym: HELIO overallStatus: RECRUITING date: 2023-06-15 date: 2025-03 date: 2025-03 date: 2024-04-09 date: 2024-04-09 name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS class: OTHER briefSummary: The goal of this interventional study is to create hepatocellular carcinoma organoids from liver bioptic samples of individuals with hepatocellular carcinoma. The main questions it aims to answer are: