hackint0sh/New-Dataset huggingface dataset:
The simulation program will include interactive case scenarios, virtual patients, and simulation sessions led by an instructor providing feedback to students. Additionally, learning materials covering topics such as prevention, recognition, and correction of medication errors will be provided conditions: Nurse studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: This study was planned as a randomized controlled study to evaluate the crisis management skills of student nurses in drug safety simulation. primaryPurpose: HEALTH_SERVICES_RESEARCH masking: SINGLE maskingDescription: The researchers declare that the data obtained from randomly formed groups will be numbered and entered into the statistical analysis program to hide the identity information and that two researchers will be assigned during the entry. whoMasked: PARTICIPANT count: 70 type: ESTIMATED name: drug safety simulation measure: The effect of drug safety simulation application on the crisis management skill level of nursing students. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06359392 id: DNZNC466DGR7 id: 1R21NR020383-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R21NR020383-01 briefTitle: Palliative Care Messaging for American Indians overallStatus: NOT_YET_RECRUITING date: 2024-04-08 date: 2024-05-15 date: 2024-05-15 date: 2024-04-11 date: 2024-04-11 name: South Dakota State University class: OTHER name: Great Plains Tribal Leaders Health Board name: National Institute of Nursing Research (NINR) briefSummary: The investigators will be conducting a randomized trial in 3 reservation communities to test the efficacy of the narrative as culture-centric health promotion model for increasing American Indian tribal members' palliative care knowledge and intentions to discuss palliative care. conditions: Knowledge, Attitudes, Practice studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 360 type: ESTIMATED name: No message name: Culture-centric message name: General messge measure: Palliative Care Knowledge Scale (PaCKS) measure: Knowledge of Care Options (KOCO) measure: Hospice and Palliative Care Questionnaire (HPCQ) measure: Identification and Transportation with Palliative Care Message measure: Attitudes and Intentions to Discuss Palliative Care sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: South Dakota State University city: Rapid City state: South Dakota zip: 57701 country: United States name: Mary J Isaacson, PhD, RN, RHNC, CHPN, FPCN role: CONTACT phone: 605-670-0975 email: mary.isaacson@sdstate.edu name: Karla Hunter, PhD role: CONTACT phone: 605-212-0894 email: karla.hunter@sdstate.edu name: Mary J Isaacson, PhD, RN, RHNC, CHPN, FPCN role: PRINCIPAL_INVESTIGATOR lat: 44.08054 lon: -103.23101 hasResults: False
nctId: NCT06359366 id: ShenzhenH-guo briefTitle: Perineal Massage Combined With Hip Joint Training overallStatus: NOT_YET_RECRUITING date: 2024-04-10 date: 2024-07-31 date: 2024-08-31 date: 2024-04-11 date: 2024-04-11 name: Shenzhen Hospital of Southern Medical University class: OTHER briefSummary: The goal of this clinical trial is to learn if perineal massage combined with hip joint training works to improve pelvic function (urinary incontinence, constipation and hip motion) in pregnant women. The main questions it aims to answer are:
receive the intervention (perineal massage combined with hip joint training ) or regular training and treatment fifth a week at 36 weeks gestation before participants receive first-time intervention, they complete Demographic sociological , ICI-Q-LF, Wexner constipation and hip motion questionnaires conditions: Pelvic Floor Disorders studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: when the participants are enrolled in this study, they will be allocated to groups randomly by an independent researcher and sign the consent form. The care providers will not know the outcomes of this study, they just provide treatment for pregnant women; therefore, the care providers could be masked. an independent investigator will send a questionnaire to the participant, and the investigator does not know the intervention participants received; thus they could be masked. whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 108 type: ESTIMATED name: perineal massage combined hip joint training measure: pelvic floor function(constipation) measure: pelvic floor function (urinary incontinence score) measure: hip motion sex: FEMALE minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT hasResults: False
nctId: NCT06359353 id: B-1902-520-004 briefTitle: Effect of Pitavastatin on Bone overallStatus: COMPLETED date: 2019-04-08 date: 2022-02-10 date: 2023-12-19 date: 2024-04-11 date: 2024-04-11 name: Seoul National University Bundang Hospital class: OTHER name: JW Pharmaceutical briefSummary: This clinical trial investigates the effects of pitavastatin on bone health in postmenopausal women with osteopenia or osteoporosis and hypercholesterolemia. Given the high prevalence of osteoporosis in aging populations and the associated risks, even with existing treatments, this study addresses a critical gap in medical research. Statins, specifically HMG-CoA reductase inhibitors, are suggested to benefit bone metabolism by promoting bone formation and reducing resorption. However, the specific impact of pitavastatin on bone metabolism lacks clinical evidence.
The study's primary goal is to determine the effects of a 12-month pitavastatin regimen on bone metabolism markers in this population. This research could significantly contribute to developing more effective osteoporosis treatments for postmenopausal women, combining bone health and cholesterol management strategies. conditions: Osteoporosis, Osteopenia conditions: Hypercholesterolemia conditions: Menopausal Osteoporosis studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: PREVENTION masking: NONE count: 70 type: ACTUAL name: Pitavastatin measure: Change in blood urinary N-Telopeptide of Type I Collagen levels compared to baseline after 6 months measure: Change in blood C-Telopeptide of Type I Collagen levels measure: Change in blood Osteocalcin levels measure: Change in urinary N-Telopeptide of Type I Collagen levels measure: Change in blood Procollagen Type 1 N-Terminal Propeptide levels measure: Change in blood LDL-cholesterol levels measure: Change in blood HbA1c levels measure: Changes in bone mineral density measure: Changes of the outcomes after 12 months sex: FEMALE maximumAge: 75 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Seoul National University Bundang Hospital city: Seongnam state: Gyeonggi zip: 463-707 country: Korea, Republic of lat: 37.43861 lon: 127.13778 hasResults: False
nctId: NCT06359340 id: OBOT-2018C2-13158 briefTitle: Therapy and Peer Support for Patients Taking Medication for Opioid Use Disorder overallStatus: RECRUITING date: 2020-03-13 date: 2024-04-30 date: 2025-04-30 date: 2024-04-11 date: 2024-04-11 name: Public Health Management Corporation class: OTHER name: Boston University name: Patient-Centered Outcomes Research Institute name: Philadelphia College of Osteopathic Medicine name: University of Pennsylvania briefSummary: Current clinical guidelines for medication assisted treatment (MAT) of opioid use disorder (OUD) recommend that treatment include a psychosocial component to help address psychological factors related to addiction. However, a knowledge gap exists regarding the most effective forms of psychosocial intervention and what interventions are most effective for different types of patients. This gap represents a significant barrier to the widespread implementation of effective office-based opioid treatment (OBOT) with buprenorphine, which is important to improving opioid treatment and responding to the critical needs of individuals living with OUD. The overarching goal of this patient-centered research is to address the diverse needs and preferences of OUD patients in regards to psychosocial approaches and to overcome the "one-size-fits-all" strategies that are typically used to treat OUD. Importantly, the investigators arrived at this goal, in part, through collaboration and consultation with former patients who have received different types of treatments for OUD. In this manner, patients provided important insight to inform the selection of interventions to be evaluated, patient characteristics that may differentially impact the effects of the interventions, and the patient outcomes to be examined. conditions: Opioid-use Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: FACTORIAL primaryPurpose: TREATMENT masking: NONE count: 440 type: ESTIMATED name: Psychosocial treatment measure: Changes in urinalysis-confirmed opioid use from baseline through one year post-study entry measure: Days Retained in Office-Based Buprenorphine Treatment measure: Changes in quality of life assessment: Short Form-36 (SF-36) from baseline through one year post-study entry measure: Changes in multidimensional problem severity from baseline through one year post-study entry measure: Changes in the percentage of individuals engaging in urinalysis-confirmed use of other (non-opioid) drugs from baseline to one year post-study entry measure: Changes in ED utilization from baseline to one year post-study entry measure: Changes in opioid overdose rates measure: Changes in treatment satisfaction from baseline to one year post-study entry measure: Job satisfaction and stress sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Philadelphia College of Osteopathic Medicine status: RECRUITING city: Philadelphia state: Pennsylvania zip: 19131 country: United States name: David S Festinger, Ph.D. role: CONTACT phone: 215-871-6546 email: DavidFe@pcom.edu lat: 39.95233 lon: -75.16379 hasResults: False
nctId: NCT06359327 id: Pro00075623 briefTitle: Effect of Consumption of Pep19 on Quality of Life overallStatus: RECRUITING date: 2024-04-17 date: 2024-07-17 date: 2024-08-15 date: 2024-04-11 date: 2024-04-19 name: Proteimax Biotechnology Israel LTD class: INDUSTRY briefSummary: Pep19 is a naturally occurring peptide (protein) that triggers loss of body fat. It has been certified Generally Recognized as Safe (GRAS) at up to 3.8 grams per day and may be included in various foods. Pep19 has no effect on the brain, heart, pancreas or skeletal muscle. It is highly purified, not allergenic or mutagenic, and free of microbes, metals and other contaminants. Preliminary, open-label, uncontrolled studies have shown that Pep19 is well tolerated in rodents, dogs, and humans. This placebo-controlled study will evaluate the effects of two doses of Pep19™ -- 2 mg and 5 mg - on quality of life and sleep quality in obese subjects. conditions: Quality of Life conditions: Obesity conditions: Sleep Quality studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: SINGLE whoMasked: PARTICIPANT count: 24 type: ESTIMATED name: Placebo name: Pep19 2 mg name: Pep19 5 mg measure: Improvement on QoL measure: Improvement on Sleep quality measure: Temperature measure: Blood pressure measure: Heart rate measure: circumference measure: blood tests measure: Body fat measure: Body weight sex: ALL minimumAge: 40 Years maximumAge: 60 Years stdAges: ADULT facility: Precision Clinical Research, LLC status: RECRUITING city: Sunrise state: Florida zip: 33351 country: United States name: Jason Haffizulla, MD role: CONTACT lat: 26.13397 lon: -80.1131 hasResults: False
nctId: NCT06359314 id: STU00219362 briefTitle: Anxiety Lowering and Deprescribing Through Emotion Regulation acronym: ALDER overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-07 date: 2024-07 date: 2024-04-11 date: 2024-04-11 name: Northwestern University class: OTHER briefSummary: The goal of this clinical trial is to test ALDER (Anxiety Lowering and Deprescribing through Emotion Regulation), an online self-guided positive emotion intervention, in patients over the age of 65 who are candidates for benzodiazepine receptor agonist (BZRA, commonly called benzos, or z-drugs) deprescribing. The main questions it aims to answer are:
Participants will complete the 5-week online self-guided ALDER intervention as well as two survey assessments, one before the intervention and one after. conditions: Benzodiazepine Dependence conditions: Anxiety Disorders conditions: Sleep Disturbance studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 40 type: ESTIMATED name: ALDER measure: Feasibility of intervention measure: Acceptability of intervention measure: Adoption of intervention measure: Patient benzodiazepine receptor agonist (BZRA) use measure: Patient attitude towards deprescribing BZRAs measure: Patient-reported sleep disturbance measure: Patient-reported anxiety measure: Patient-reported stress measure: Patient-reported depression measure: Patient-reported positive affect measure: Patient-reported meaning and purpose measure: Patient-reported comorbidities sex: ALL minimumAge: 65 Years stdAges: OLDER_ADULT hasResults: False
nctId: NCT06359301 id: H-34 briefTitle: H-34 DELTA Revision Cup overallStatus: RECRUITING date: 2021-09-14 date: 2026-03-31 date: 2029-03-31 date: 2024-04-11 date: 2024-04-11 name: Limacorporate S.p.a class: INDUSTRY briefSummary: THis study is aimed to provide a clinical and radiographic evaluation of 49 suitable subjects who underwent a total hip arthroplasty with DELTA Revision acetabular cup. conditions: Hip, Osteoarthritis studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 49 type: ESTIMATED name: DELTA Revision acetabular cup measure: Harris Hip Score (HHS) measure: ROM measurement measure: Oxforn Hip Score (OHS) measure: Survival rate measure: Radiographic implant evaluation and stability assessment of the DELTA Revision acetabular cup measure: Incidence, type and severity of all the Adverse Events (AEs), Serious Adverse Events (SAEs), Adverse Device Effects (ADEs), and Serious Adverse Device Effects (SADEs) occurred at each follow-up sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Samodzielny Publiczny Szpital Kliniczny im. Prof. Adama Grucy CMKP status: RECRUITING city: Otwock zip: 05-400 country: Poland name: Jerzy Bialecki role: CONTACT lat: 52.10577 lon: 21.26129 hasResults: False
nctId: NCT06359288 id: 2023/01.11/2023/6 briefTitle: Preterm Newborn Mothers' Anxiety and Self-Efficacy overallStatus: COMPLETED date: 2023-01-01 date: 2023-12-01 date: 2024-03-23 date: 2024-04-11 date: 2024-04-11 name: Kocaeli University class: OTHER briefSummary: The aim of this study was to evaluate the effect of QR code supported infant care training given to mothers of preterm newborns on maternal self-efficacy and maternal anxiety level . conditions: Nursing Care conditions: Mother-Infant Interaction conditions: Education studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The study was conducted experimentally with a pre-test and post-test control group. primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE maskingDescription: Double blinding was used in the study. For this purpose, the participants were not specified in which group they belonged to the research. Therefore, a separate informed consent form was prepared for each group. In order to avoid bias in the analysis of the research data, statistician blinding was also applied.
While coding the research data, the research groups were coded as A and B, and the statistician was prevented from knowing which letter represented which group. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 80 type: ACTUAL name: Group receiving QR code supported training measure: Perceived Maternal Self-Efficacy Scale (PMES)- Survey measure: State-Trait Anxiety Inventory (STAI)- Survey Scale sex: FEMALE minimumAge: 19 Years maximumAge: 45 Years stdAges: ADULT facility: Kocaeli University city: Kocaeli state: İzmit zip: 41380 country: Turkey lat: 39.62497 lon: 27.51145 hasResults: False
nctId: NCT06359275 id: iPULSAR-PC briefTitle: PD-1 Combined With Chemotherapy and PULSAR in LAPC and Local Recurrence Patients overallStatus: RECRUITING date: 2024-04-01 date: 2025-12-01 date: 2027-10-01 date: 2024-04-11 date: 2024-04-11 name: Fudan University class: OTHER briefSummary: This trial is a phase II clinical trial of the safety and efficacy of PD-1 antibody (Toripalimab) in combination with paclitaxel (albumin-bound type) and gemcitabine and PULSAR radiotherapy in patients with locally advanced unresectable pancreatic cancer and patients with only local recurrence after pancreatic cancer surgery, to observe the safety and efficacy of PD-1 antibody (Toripalimab) in combination with paclitaxel (albumin-bound type) and gemcitabine and PULSAR in the treatment of patients with locally advanced unresectable pancreatic cancer. conditions: Pancreatic Cancer studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: NONE count: 81 type: ESTIMATED name: PD-1 name: Nab-paclitaxel name: Gemcitabine name: PULSAR measure: Progression-free survival (PFS) measure: Progression-free survival (ORR) measure: Overall survival (OS) measure: Surgical Conversion Rate sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fudan University Shanghai Cancer Center status: RECRUITING city: Shanhai country: China name: Weijing Zhang role: CONTACT phone: 021-64175590 email: andwater@163.com hasResults: False
nctId: NCT06359262 id: KI-HAS-001 briefTitle: Evaluating the Hope@School Prevention Program acronym: Hope@School overallStatus: NOT_YET_RECRUITING date: 2027-01-01 date: 2027-12-30 date: 2028-12-30 date: 2024-04-11 date: 2024-04-11 name: Karolinska Institutet class: OTHER briefSummary: This multi-center cluster-randomized controlled trial aims to evaluate the feasibility, effectiveness and overall impact of the Hope@School (H@S) program by comparing mental health outcomes in students participating in the H@S program with students having only access to regular student health care (treatment as usual - TAU).
To determine if the H@S program is feasible, acceptable, usable and safe for students, families, teachers and school leaders To establish if the H@S program is associated with improvements in quality of life, everyday functioning, peer relations and general mental health. conditions: Mental Health Wellness 1 studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 3220 type: ESTIMATED name: Hope@School name: Treatment as usual measure: KIDSCREEN-27 Child version measure: KIDSCREEN-27 Parent version measure: Mental Health-Promoting Knowledge (MHPK-10) measure: Healthy Behaviours in School-aged Children survey protocol (HBSC) part 1 measure: Digital Addiction Scale for Children (DASC) measure: Healthy Behaviours in School-aged Children survey protocol (HBSC) part 2 sex: ALL minimumAge: 8 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT hasResults: False
nctId: NCT06359249 id: V.3-06/02/2024 briefTitle: Do the Symptoms of Chronic Constipation Improve With a Primary Care Programme Based on Behavioural Re-education and Abdominal Massage? overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-01 date: 2026-12-28 date: 2026-12-28 date: 2024-04-11 date: 2024-04-11 name: Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina class: OTHER name: Universitat de Vic briefSummary: Constipation is one of the most common digestive problems in today's society. In Spain, it is estimated that this condition affects between 12% and 20% of the population, being more frequent in women, contributing considerably to the quality of life, to the increase of medical visits and to high costs for the health system. The objectives of the study are to reduce the rate of constipation and laxative use in the short term with a structured rehabilitation programme consisting of abdominal massage therapy and behavioural re-education, to improve the quality of life of these patients, and to assess whether the proposed treatment is effective in the short and medium term. conditions: Constipation Chronic Idiopathic studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 45 type: ESTIMATED name: change of habits name: change of habits + auto abdominal massage measure: Degree of constipation measure: Stool characteristics measure: Quality of life focused on patients with constipation measure: The number of laxatives taken by each participant measure: Other patient characteristics such as sex, age, previous conditions, and level of physical activity with the VREM questionnaire. sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Cristina Segura Bayona city: Igualada state: Barcelona zip: 08700 country: Spain lat: 41.58098 lon: 1.6172 hasResults: False
nctId: NCT06359236 id: 122S049 briefTitle: Development and Effectiveness of Cognitive Behavioral Therapy Based Weight Control Mobile Application "BI'KILO" overallStatus: ACTIVE_NOT_RECRUITING date: 2022-06-01 date: 2024-01-01 date: 2024-04-01 date: 2024-04-11 date: 2024-04-11 name: Eskisehir Osmangazi University class: OTHER name: The Scientific and Technological Research Council of Turkey briefSummary: The primary purpose of this project is to observe the effects of Cognitive Behavioral Psychotherapy-based weight-loss mobile application (Bi' Kilo) in 4 essential areas (Anthropometric, Biochemical, Psychometric, Cognitive) in overweight and obese individuals and to test whether these effects will persist after ten weeks. In this context, the original value of the proposed study is that a mobile application will be produced that is suitable for the culture and whose effectiveness has been scientifically proven.
The study group of the research will consist of overweight and obese individuals. The first stage will be a pilot study to identify the shortcomings of the Bi'Kilo mobile application. After eliminating the deficiencies of the Bi' Kilo mobile application, a working group will be formed in the second phase of the research. At this stage, the sample will be divided into two different groups within the scope of the study and a study group and a control group will be formed.