hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06372405 id: PSP-501/D125/79/00000 briefTitle: Instructed Cognitive Reappraisal in Reducing Affective, Behavioral and Psychophysiological Symptoms of Misophonia overallStatus: RECRUITING date: 2024-03-18 date: 2024-12 date: 2025-09-30 date: 2024-04-18 date: 2024-04-18 name: University of Warsaw, Poland class: OTHER name: Duke University briefSummary: Misophonia is a disorder causing intense reactions to specific sounds, disrupting daily life. Current treatments lack evidence-based support. The goal of this study is to explore the effectiveness of cognitive reappraisal (CR) in reducing misophonic responses. The study involves 100 participants assigned to either a 4-week CR program or Autogenic Training. Emotional regulation, symptoms of anxiety and depression, quality of life, and more will be assessed using various questionnaire-based measures; perseverations with a task-based test (Wisconsin Card Sorting Test); the presence of psychiatric and personality disorders using face-to-face interviews (The Mini-International Neuropsychiatric Interview (M.I.N.I.) and "Structured Clinical Interview for DSM-5® Personality Disorders" (SCID-5-PD) conditions: Misophonia Treatment studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 108 type: ESTIMATED name: Cognitive reappraisal name: Schultz Autogenic Training measure: Change in misophonia symptoms measured by S-Five - Externalizing subscale measure: Change in misophonia symptoms measured by S-Five - Internalizing subscale measure: Change in misophonia symptoms measured by S-Five - Threat subscale measure: Change in misophonia symptoms measured by S-Five - Impact subscale measure: CHange in misophonia symptoms measured by S-Five - Outburst subscale measure: Change of aversiveness rating (valence/pleasure) on the Manikin Scales. measure: Change of arousal rating on the Manikin Scales. measure: Change in Galvanic Skin Response measure: Change in average HR during the trigger presentation measure: Diagnosis of personality disorders as a predictor of worse treatment outcome. measure: Working Alliance Inventory will be related to better treatment outcomes. measure: Meeting criteria for psychiatric disorders - measure: Hearing test - standard and high frequency pure-tone audiometry sex: ALL minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: Faculty of Psychology, University of Warsaw status: RECRUITING city: Warsaw state: Masovian Voivodeship zip: 00-183 country: Poland name: Marta Siepsiak, PhD role: CONTACT phone: 0048661152533 email: marta.siepsiak@psych.uw.edu.pl name: Marta Siepsiak, PhD role: PRINCIPAL_INVESTIGATOR lat: 52.22977 lon: 21.01178 hasResults: False
nctId: NCT06372392 id: 1.0 briefTitle: Universal Fixed Meal Boluses Usage in Patients With Medtronic Minimed 780G Pumps overallStatus: RECRUITING date: 2023-10-10 date: 2024-06-10 date: 2024-12-01 date: 2024-04-18 date: 2024-04-18 name: Tartu University Hospital class: OTHER name: Estonia Research Council briefSummary: Cross-over study of 20 pediatric patients (age 7-19) randomized to the group receiving universal fixed meal boluses coefficients (300/TDD for breakfast and 400/TDD other meal) or to the group with individualized coefficients for the period of 14 days with consecutive analysis of the results from Carelink Raport. conditions: Type1diabetes studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 20 type: ESTIMATED name: Universal meal coefficient utilization measure: Time in range (TIR) measure: TBR measure: TAR measure: auto-corrections % measure: coefficient of variability sex: ALL minimumAge: 7 Years maximumAge: 19 Years stdAges: CHILD stdAges: ADULT facility: TartuUH status: RECRUITING city: Tartu state: Tartumaa zip: 50406 country: Estonia name: Aleksandr Peet role: CONTACT phone: 5532256 email: aleksandr.peet@kliinikum.ee lat: 58.38062 lon: 26.72509 hasResults: False
nctId: NCT06372379 id: 8780_UC2 briefTitle: Development of a Multipurpose Dashboard to Monitor the Situation of Emergency Departments acronym: eCREAM-UC2 overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2025-01 date: 2027-09 date: 2024-04-18 date: 2024-04-18 name: Mario Negri Institute for Pharmacological Research class: OTHER name: Astir S.r.l. name: Orobix Life S.r.l. name: Fondazione Bruno Kessler briefSummary: An emergency department (ED) is a healthcare service that provides the first clinical assessment and treatment to patients with various acute conditions. These departments, however, are often overwhelmed by the large volume of patients. As a consequence, ED crowding has become a global concern and has been correlated to reduced timeliness and effectiveness of care and increased patient mortality. Concerning input, 20% to 30% of patients are brought to the ED by ambulance; the remaining are self-presenting for the vast majority. Notably, non-urgent conditions characterize a high proportion of all ED visits worldwide, and almost all of these visits involve self-presenting patients. Increasing the awareness of these patients about the mandate of EDs and the real-time situation of the neighboring emergency departments has the potential to reduce the self-presentation of patients with minor, non-urgent conditions. Such patient empowerment can be achieved through a dashboard. Concerning throughput, working in the ED requires emergency physicians and nurses to treat many patients at once while maintaining situational awareness of the surroundings. This is especially true for the head of the department, but it also holds for all physicians. It can be crucial, for example, for physicians to know if there is a bottleneck in the flow of the entire patient care process, such as a particularly high average waiting time for radiology reporting or cardiologic consultation. The availability of this information allows countermeasures to be put in place to regain efficiency. All this can be achieved through dedicated dashboards automatically fed from various information system. In addition, appropriate dashboards also enable health policymakers to monitor specific epidemiological phenomena, such as the emergence of certain infectious diseases, in a timely manner. conditions: Emergency Medicine studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 162000 type: ESTIMATED name: no intervention measure: Daschboards sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06372366 id: Dental caries and vit.difiency briefTitle: Relationship Between Vitamins Deficiency and Caries Experience Among a Group of Egyptian Children overallStatus: NOT_YET_RECRUITING date: 2024-07-15 date: 2024-10-15 date: 2025-12-15 date: 2024-04-18 date: 2024-04-19 name: Cairo University class: OTHER briefSummary: Dental caries is a worldwide condition characterized by localized destruction of dental hard tissue by acidic by-products from bacterial fermentation of dietary carbohydrates . Dental caries is considered to be the single most common chronic childhood disease, and its prevalence is thought to have increased recently. conditions: Dental Caries conditions: Vitamin Deficiency studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 2 type: ESTIMATED measure: Caries prevalence sex: ALL minimumAge: 3 Years maximumAge: 5 Years stdAges: CHILD hasResults: False
nctId: NCT06372353 id: 777 briefTitle: The Effect Of Baduanjin Exercises In Patients With Idiopathic Pulmonary Fibrosis overallStatus: COMPLETED date: 2022-06-01 date: 2023-05-24 date: 2023-06-06 date: 2024-04-18 date: 2024-04-18 name: Marmara University class: OTHER briefSummary: Introduction and Objectives:IPF, characterized by shortness of breath and progressive deterioration in lung function.Baduanjin (BJ) is a mindbody health exercise that combines physical exercise with psychological properties to maximize both physical and mental health.The aim of the study is to investigate the effectiveness of these exercises in patients with IPF and to present an alternative in terms of the applicability of BJ exercises as a new treatment method
Methods: 28 volunteers were invited to the study.These patients were randomly divided into 2 groups.The subjects in the exercise group were given 24 sessions of supervised online BJ exercise training, 3 days a week, for 8 weeks. The patients included in the control group did not receive any training during the 8 week period conditions: Pulmonary Fibrosis, Idiopathic studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 28 type: ACTUAL name: Baduanjin Exercise measure: Functional capacity measure: Pulmonary Function Tests measure: Pulmonary Function Tests measure: Pulmonary Function Tests measure: Pulmonary Function Tests measure: Respiratory muscle strength measure: Respiratory muscle strength measure: St. George's Respiratory Questionnaire sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: İstanbul University - Cerrahpaşa city: Istanbul state: Fatih country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06372340 id: 2023BJYYEC-217-01 briefTitle: Intelligent Diagnosis and Treatment System for Pelvic Floor Dysfunction in Elderly Women overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2025-08-31 date: 2025-12-31 date: 2024-04-18 date: 2024-04-18 name: Beijing Hospital class: OTHER_GOV briefSummary: The aim of this study is to propose an intelligent diagnosis and treatment system for for pelvic floor dysfunction in elderly women. The main question it aims to answer: 1) How can the investigators find out early if older women have different pelvic floor muscle functions? 2）How can the investigators give personalized treatment plans based on differences in pelvic floor function? Participants will be assigned different training programs by the system. The investigators will compare the treatment effects and costs of older women with pelvic floor dysfunction using and not using the system. All the participants will be offered examinations for pelvic floor function and different treatments. All examinations and treatments are non-invasive. conditions: Pelvic Organ Prolapse conditions: Urinary Incontinence conditions: Diagnosis studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The participants will be allocated to experimental group(EG) or the control group(CG). Subjects in the experimental group (EG) will receive personalized pelvic floor muscle training guidance provided by the system, whereas subjects in the control group(CG) will exercise according to the handbook or oral guidance. primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Assessments regarding pelvic floor muscle strength will be conducted by an assessor blind to treatment allocation. The assessor will go through a profound assessment training program. Due to the nature of the intervention neither participants nor care providers can be blinded to allocation, but are strongly inculcated not to disclose the allocation status of the participant at the follow up assessments. An employee outside the research team will feed data into the computer in separate datasets so that the researchers can analyse data without having access to information about the allocation. whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 300 type: ESTIMATED name: Personalized pelvic floor rehabilitation program generated by the intelligent diagnosis and treatment system. name: Standard pelvic floor muscle training(PFMT) program measure: Modified Oxford Scale (MOS) measure: Surface Electromyography Data measure: The score of Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) measure: The score of the Pelvic Floor Distress Inventory (PFDI-20) measure: Subjective staging used Pelvic Organ Prolapse Quantification (POP-Q) System sex: FEMALE minimumAge: 60 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06372327 id: 73468 briefTitle: Move Often eVery Day 2.0 acronym: MOVD overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2026-07 date: 2024-04-18 date: 2024-04-19 name: Stanford University class: OTHER briefSummary: The purpose of this study is to assess a novel, widely-accessible intervention to both promote active breaks from work and improve cognitive and psychological performances at work in motivationally-accessible bouts. This will be done by interrupting prolonged sitting with 1-4 short (1-4 minutes), moderate-to-vigorous physical activity (MVPA) bouts with no equipment, and simple video-based instructions. The short bouts will be referred to as "exercise snacks." In this proposed exercise snacks intervention, investigators explicitly target a population with sedentary jobs due to the generalizability. conditions: Exercise studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: FACTORIAL interventionModelDescription: This will be a 2 (Exercise snack number) x 2 (Exercise snack length) factorial design. primaryPurpose: PREVENTION masking: NONE count: 40 type: ESTIMATED name: Daily Exercise Snacks measure: Number of self-reported exercise snack breaks at work at week 7 measure: Number of self-reported exercise snack breaks at work at week 18 measure: Number of self-reported exercise snack breaks at work at week 30 during follow-up measure: Liking of exercise snacks sex: FEMALE minimumAge: 30 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Stanford University School of Medicine city: Stanford state: California zip: 94305-7240 country: United States lat: 37.42411 lon: -122.16608 hasResults: False
nctId: NCT06372314 id: 1000081221 briefTitle: Isoleucine, Leucine, Valine and Tryptophan Requirements in TPN Fed Neonates overallStatus: NOT_YET_RECRUITING date: 2024-08 date: 2027-12 date: 2027-12 date: 2024-04-18 date: 2024-04-18 name: The Hospital for Sick Children class: OTHER briefSummary: This project will be conducted in 2 hospitals in Brazil to assess the requirements for four essential amino acids in TPN fed neonates. Using the Carbon Oxidation method (indicator amino oxidation and direct amino acid oxidation method), the investigators will determine the requirement of each of the 4 amino acids.
The investigators will determine the requirement for Isoleucine, Leucine, Valine and Tryptophan. The investigators will recruit 18- 20 babies per amino acid study. Breath and urine samples will be collected to determine the oxidation of the indicator amino acid. The response of the indicator amino acid to changes in intake of the test amino acid (isoleucine, leucine, valine and tryptophan) will be analyzed by bi-phase linear mixed effect model to determine the breakpoint or mean requirement for each amino acid. It is hypothesized that the requirement for isoleucine, leucine, valine and tryptophan will be at least 50% lower than what is currently available in commercial solutions used for TPN feeding of neonates. conditions: Stable Neonates Receiving Total Parenteral Nutrition (TPN) studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 80 type: ESTIMATED name: Total parenteral nutrition (TPN): this is total nutrition provided by central vein. measure: Amino acid oxidation using a labelled amino acid. sex: ALL minimumAge: 1 Day maximumAge: 28 Days stdAges: CHILD facility: Hospital de Caridade Dr. Astrogildo de Azevedo, and University Hospital of Santa Maria, Santa Maria, Brazil city: Santa Maria country: Brazil name: Ivo Dr Prola, MD, PhD role: CONTACT phone: 6477815786 email: iprolla@gmail.com name: Beatriz Dr Porto, MD role: CONTACT phone: 6475002171 email: bsilveiraporto@gmail.com lat: -29.68417 lon: -53.80694 hasResults: False
nctId: NCT06372301 id: 1-10-72-179-23 briefTitle: Dobutamine Stress Echocardiography in LF/LG Aortic Stenosis and Wild-type Transthyretin Amyloid Cardiomyopathy acronym: DobAttrAS overallStatus: RECRUITING date: 2024-04-02 date: 2025-11-01 date: 2026-04-01 date: 2024-04-18 date: 2024-04-18 name: Steen Hvitfeldt Poulsen class: OTHER briefSummary: The goal of this prospective clinical study is improve the diagnosis of Low-flow low-gradient aortic stenosis (LF/LG AS), in patients with co-existing wild-type transthyretin cardiac amyloidosis (ATTRwt). The main question it aims to answer is whether the classic dobutamine-stress echocardiography can be used to determine AS severity in patients with ATTRwt and LF/LG AS This question will be tried to answer by comparing dobutamine stress echocardiography, with the invasively measured aortic valve area (which is considered as the gold standard).
In addition we aim to assess the degree of myocardial fibrosis and amyloid infiltration, assessed by light microscopy and cardiac magnetic resonance (CMRI) and evaluation of myocyte mitochondrial function by high resolution respirometry and their relation to AS severity and hemodynamic response to dobutamine. conditions: Transthyretin Amyloid Cardiomyopathy conditions: Aortic Stenosis studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 24 type: ESTIMATED name: Dobutamine stress echocardiography measure: The correlation between echocardiography derived projected aortic valve area (AVAproj) and invasively assessed AVAproj under dobutamine infusion. measure: Correlation between echocardiography derived AVA and invasively assessed AVA at rest and at different dobutamine infusion levels. measure: Increase of SVI, LV ejection fraction and LV-global longitudinal strain of 10 % during maximal dobutamine stimulation. measure: Correlation between echo- and invasive measured SVI. measure: Degree of myocardial fibrosis, amyloid infiltration and mitochondrial dysfunction and its relation to AS severity and hemodynamic response to dobutamine measure: Reduction of mean pulmonary artery wedge pressure and/or mean pulmonary artery pressure by 10 %. measure: Complication rate and symptomatic side effects during dobutamine challenge sex: ALL minimumAge: 65 Years stdAges: OLDER_ADULT facility: Department of Cardiology, Aarhus University Hospital status: RECRUITING city: Aarhus zip: 8200 country: Denmark name: Ali Hussein Jaber Mejren, MD role: CONTACT phone: 0045 91 65 18 48 email: alimej@clin.au.dk lat: 56.15674 lon: 10.21076 hasResults: False
nctId: NCT06372288 id: 22-1754 briefTitle: Theta Burst TMS for Treatment of Methamphetamine Use Disorder overallStatus: RECRUITING date: 2023-12-20 date: 2024-12 date: 2025-12 date: 2024-04-18 date: 2024-04-26 name: Carilion Clinic class: OTHER name: Virginia Polytechnic Institute and State University briefSummary: This study is using Transcranial Magnetic Stimulation (TMS) to determine if interventional psychiatry treatment can help with the treatment of Methamphetamine Use Disorder. Individuals with Methamphetamine Use Disorder will receive 5 consecutive TMS treatment sessions based off of randomization. Participants will be randomized to one of two groups. TMS treatment arm or sham-TMS arm. conditions: Methamphetamine Abuse studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Participants will be randomized to either receive 5 transcranial magnetic stimulations or 5 sham transcranial magnetic stimulation (no therapeutic levels of stimulation) sessions. primaryPurpose: TREATMENT masking: TRIPLE maskingDescription: One study personnel not involved in participant interventions will be unblinded and will randomize participants and confirm the set up of the device for the session prior to the blinded study personnel interacting with the participant. Both the participant and the blinded study personnel will not know which group the participant will be part of throughout the study sessions. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 40 type: ESTIMATED name: Transcranial Magnetic Stimulation name: Sham Transcranial Magnetic Stimulation measure: Stimulant Craving Questionnaire (STCQ) measure: Urine Drug Screen (UDS) measure: Generalized Anxiety Disorder-7 (GAD-7) measure: Patient Health Questionnaire-9 (PHQ-9) measure: Quality - Life Enjoyment Scale - Questionnaire (Q-LES-Q) measure: Hamilton Anxiety Scale (HAM-A) measure: Montgomery Asberg Depression Rating Scale (MADRS) measure: Clinical Global Impression - Severity (CGI-S) measure: Clinical Global Impression - Improvement (CGI-I) sex: ALL minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: Carilion Clinic status: RECRUITING city: Roanoke state: Virginia zip: 24014 country: United States name: Sooraj John, M.D. role: CONTACT name: Maryann Hollen, B.S. role: CONTACT phone: 540-566-8081 lat: 37.27097 lon: -79.94143 hasResults: False
nctId: NCT06372262 id: Rowers2022 briefTitle: Effect of 2000-meter Rowing Test on Parameters of Intestinal Integrity in Elite Rowers During Competitive Phase acronym: Rowers overallStatus: COMPLETED date: 2022-06-01 date: 2022-06-30 date: 2022-06-30 date: 2024-04-17 date: 2024-04-17 name: Poznan University of Physical Education class: OTHER briefSummary: The study aimed to check the 2000m ergometer test on markers of gut permeability in the competitive phase of rowers. 18 members of the Polish rowing team took part in the study. conditions: Endothelial Dysfunction studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 18 type: ACTUAL name: ergometer test measure: I-FABP (intestinal fatty acid binding protein)to measure epithelial wall injury measure: zonulin to measure tight junction leakage measure: LBP (lipopolysaccharide binding protein) to measure endotoxin measure: LPS (lipopolysaccharide) to measure endotoxin measure: Lactic acid to measure fatigue after the race measure: energy measure: fiber intake measure: protein measure: carbohydrate measure: body mass measure: Body composition - water measure: Body composition - fat measure: Lean body mass sex: MALE minimumAge: 18 Years maximumAge: 23 Years stdAges: ADULT facility: Poznan University of Physical Education city: Poznań country: Poland lat: 52.40692 lon: 16.92993 hasResults: False