hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06342102 id: ID 4286 briefTitle: PENG and LFCN Block Versus FIC Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis Focused on Movement (Retro-PvF) acronym: Retro-PvF overallStatus: NOT_YET_RECRUITING date: 2024-03-26 date: 2024-03-26 date: 2024-04-30 date: 2024-04-02 date: 2024-04-04 name: Ospedale Edoardo Bassini class: OTHER briefSummary: Total hip arthroplasty is a major surgical procedure performed on a growing number of patients. Optimal pain control with limited muscle weakness is paramount for a swift initiation of physical therapy and ambulation, thus expediting hospital discharge. Amongst the many peripheral nerve blocks, FIB (fascia iliaca block) has been recommended as the block of choice by many international guidelines since it offers the best pain control with a relatively low risk of motor block. PENG (pericapsular nerve group) and its association with LFCN (lateral femoral cutaneous nerve) has been proposed as an effective alternative that offers comparable, If not better, pain control with a considerably lower risk for motor block compared to FIB. Given the novelty of this block, there are few published papers on the subject, mostly case series or case reports thus justifying the need for retrospective study. conditions: Regional Anesthesia Block conditions: Regional Anesthesia conditions: Total Hip Replacement Surgery conditions: Total Hip Arthroplasty \(THA\) studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 80 type: ESTIMATED name: PENG + LFCN block name: FIC block measure: Movement of the lower limb affected by surgery measure: pain control measure: pain control measure: pain control measure: Morphine Milligram Equivalents (MME) of "pro re nata" (PRN) opioid doses measure: Morphine Milligram Equivalents (MME) of "pro re nata" (PRN) opioid doses measure: Morphine Milligram Equivalents (MME) of "pro re nata" (PRN) opioid doses measure: time to first opioid request measure: time to first postoperative ambulation sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06342089 id: NCT06342089 briefTitle: Association Between Molar Incisor Hypomineralization And Type I Diabetes Milletus. overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2024-11 date: 2025-05 date: 2024-04-02 date: 2024-04-05 name: Cairo University class: OTHER briefSummary: * Determine the association between molar incisor hypomineralization and type I diabetes millutes, its severity and treatment need via clinical examination of children with type I diabetes millutes .
* The results of the study will be regularly monitored by the supervisors who will have full access to these results. conditions: Molar Incisor Hypomineralization studyType: OBSERVATIONAL observationalModel: ECOLOGIC_OR_COMMUNITY timePerspective: RETROSPECTIVE count: 238 type: ESTIMATED name: Type I diabetes milletus measure: Association between molar incisor Hypomineralization and type I diabetes milletus measure: Severity of molar incisor Hypomineralization among among a group of children with type I diabetes milletus. measure: Treatment need sex: ALL minimumAge: 8 Years maximumAge: 14 Years stdAges: CHILD hasResults: False
nctId: NCT06342076 id: 2023-596 briefTitle: Comparison of the Efficacy of Peripheral Nerve Blocks in Major Open Gynaecological Cancer Surgery overallStatus: COMPLETED date: 2024-01-01 date: 2024-03-01 date: 2024-03-01 date: 2024-04-02 date: 2024-04-02 name: Bakirkoy Dr. Sadi Konuk Research and Training Hospital class: OTHER_GOV briefSummary: The aim of this prospective randomized study was to compare the effectiveness of subcostal transversus abdominis plane block or rectus sheath block applied in addition to posterior transversus abdominis plane block for postoperative analgesia in major gynecological cancer surgeries.
\[Is subcostal transversus abdominis plane block more effective in postoperative analgesia? \] \[Is there a difference in pain scores at 24 hours after surgery? \] Since pain scores within the first 24 hours after surgery will be evaluated, participants will be asked to give a value between 0 and 10 at certain time periods. conditions: Postoperative Pain conditions: Postoperative Complications conditions: Analgesia conditions: Regional Anesthesia Morbidity studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Prospective randomize study primaryPurpose: SUPPORTIVE_CARE masking: NONE maskingDescription: Prospective randomize study count: 50 type: ACTUAL name: Patients undergoing subcostal transversus abdominis plane block and posterior transversus abdominis plane block name: Patients undergoing rectus sheat block and posterior transversus abdominis plane block measure: visuel analog scale measure: amount of opioid used sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Başakşehir Çam and Sakura City Hospital city: Istanbul state: Basaksehir country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06342063 id: 20-0070-E briefTitle: The Effects of Preoperative Blood Flow Restriction Training in Patients Undergoing ACL Reconstruction acronym: BFRACL overallStatus: COMPLETED date: 2021-04-01 date: 2023-10-31 date: 2024-01-31 date: 2024-04-02 date: 2024-04-02 name: Women's College Hospital class: OTHER briefSummary: This prospective feasibility study is designed to assess pre-operative BFR in patients awaiting ACL reconstruction. This study will serve the following: (1) to determine if BFR improves strength testing prior to surgery and (2) to determine if BFR reduces QF muscle group atrophy prior to surgery. Additionally, preliminary results on pre-operative clinical and quality of life scores will be collected. If this study shows encouraging results, it will serve as a template for a more comprehensive randomized control trial. conditions: ACL Injury conditions: Sports Physical Therapy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Patients were recruited and randomized to one of the two treatment arms. primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Outcome measurement was blinded to participant intervention. whoMasked: OUTCOMES_ASSESSOR count: 32 type: ACTUAL name: Blood Flow Restriction Therapy name: Blood Flow Restriction Therapy Sham measure: Biodex Strength Testing measure: Short Form Health Survey 12 (SF-12) measure: Knee Injury and Osteoarthritis Outcome Score (KOOS) sex: ALL minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Mount Sinai Hospital city: Toronto state: Ontario zip: M5G 1X5 country: Canada lat: 43.70011 lon: -79.4163 typeAbbrev: Prot hasProtocol: True hasSap: False hasIcf: False label: Study Protocol date: 2022-10-28 uploadDate: 2024-03-07T20:51 filename: Prot_000.pdf size: 303762 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2022-10-28 uploadDate: 2024-03-23T13:30 filename: ICF_001.pdf size: 892575 hasResults: False
nctId: NCT06342050 id: STU-2023-0548 id: R01MD011686 type: NIH link: https://reporter.nih.gov/quickSearch/R01MD011686 briefTitle: Socioecological Factors Associated With Ethnic Disparities in Bariatric Surgery Utilization and Post-WLS overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-02 date: 2025-08 date: 2024-04-02 date: 2024-04-02 name: University of Texas Southwestern Medical Center class: OTHER name: National Institute on Minority Health and Health Disparities (NIMHD) briefSummary: The goal of this cross-sectional observational study is to examine potential relationships between the blood and gut microbiota of patients with obesity before and after weight loss surgery (WLS) and evaluate potential ethnic differences in the blood and gut microbiotas before and after the WLS.
Hypothesis2: Ethnic differences will be detected in both the pre- and post-WLS groups. conditions: Obesity conditions: Metabolic Syndrome studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 100 type: ESTIMATED measure: Gut Microbial Composition measure: Blood Microbial Composition measure: Body Weight (kg) measure: Body Height (meters) measure: Fat Mass (Kg) measure: Fat-free Mass (Kg) measure: Body water (%) measure: Skeletal Muscle Mass (kg) measure: Fasting Glucose (mg/dL) measure: Fasting Insulin (mIU/L) measure: Lipopolysaccharides (%) measure: Lipopolysaccharides binding protein (mIU/L) sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2024-03-19 uploadDate: 2024-03-27T14:38 filename: Prot_SAP_000.pdf size: 316789 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2024-03-19 uploadDate: 2024-03-27T14:39 filename: ICF_001.pdf size: 297665 hasResults: False
nctId: NCT06342037 id: N22TON briefTitle: NOvel Immunotherapy Strategies for Advanced Triple Negative Breast Cancer (TNBC) Patients: TONIC-3 Trial acronym: TONIC-3 overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2026-04-01 date: 2030-04-01 date: 2024-04-02 date: 2024-04-18 name: The Netherlands Cancer Institute class: OTHER name: Hoffmann-La Roche briefSummary: This is a single center, non-blinded, multi-cohort, non-comparative phase II trial to study the safety and efficacy of tiragolumab with atezolizumab and/or ipilimumab in advanced triple-negative breast cancer. conditions: Metastatic Breast Cancer studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 60 type: ESTIMATED name: Tiragolumab name: Atezolizumab name: Ipilimumab measure: PFS-12 measure: Incidence of adverse events measure: Objective response rate measure: Clinical benefit rate measure: Progression-free survival measure: Overall survival sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06342024 id: 23-871 briefTitle: Pistachio Consumption on Inflammatory Markers and Lean Body Mass overallStatus: RECRUITING date: 2024-02-20 date: 2025-05-30 date: 2025-08-31 date: 2024-04-02 date: 2024-04-02 name: Virginia Polytechnic Institute and State University class: OTHER briefSummary: Pistachio nuts (Pistacia vera L.) are a nutrient- and energy-dense food, and are a significant source of 15 different micronutrients. In addition to an excellent micronutrient profile, pistachios are a good source of monounsaturated and polyunsaturated fats (linoleic acid, oleic acid, and plant sterols). Pistachios have the lowest amount of total fat, and the highest protein, fiber, and phytosterol content compared to other nuts. They possess a high antioxidant content. Specifically, pistachios have high amounts of lutein, zeaxanthin, and phenolic compounds (e.g., anthocyanins, flavonoids, and proanthocyanidins). These aforementioned compounds are known for their anti-inflammatory effects. Pistachios also have been shown to reduce the risk of cardiovascular disease, metabolic syndrome, and all-cause mortality.
The purpose of this study will be to determine the effects of consuming 1.5 ounces of pistachios per day compared to consuming no pistachios per day on inflammatory markers (creatine kinase, C-reactive protein, cortisol, Interleukin-8, tumor necrosis factor-alpha, copper-zinc superoxide dismutase, and glutathione peroxidase concentrations) and lean body mass in women and men, 40 to 60 years of age, who have been recreationally active for at least six months (exercising three to five days per week). It is hypothesized that pistachio consumption will significantly lower inflammatory response and significantly increase lean body mass.
The overall goal of this study is to evaluate the effects of pistachio consumption on inflammatory markers and lean body mass in women and men, 40 to 60 years of age, who exercise three to five days per week. This study could provide a simple, healthy way for recreationally active individuals to decrease inflammation and improve body composition. conditions: Inflammatory Response studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Eligible participants will be randomized to one of two groups (pistachio vs. control) using permuted block randomization with stratification to balance assignment by sex. Randomization allocation tables will be created by a biostatistician not involved in the clinical trial using SAS software, version 9.4 (SAS Institute, Cary, NC, USA). The tables will be stored within the REDCap system at Virginia Tech, in such a way that only the biostatistician will be able to view them. Study outcomes will be analyzed blind to allocation status. primaryPurpose: OTHER masking: NONE maskingDescription: Not apply count: 144 type: ESTIMATED name: Pistachio group measure: C-reactive protein concentrations in the blood measure: Creatine kinase concentrations in the blood measure: Cortisol concentrations in the blood measure: Interleukin-8 concentrations in the blood measure: Tumor necrosis factor-alpha concentrations in the blood measure: Copper-zinc superoxide dismutase concentrations in the blood measure: Glutathione peroxidase concentrations in the blood measure: Lean body mass measure: Body weight measure: Height measure: Body Mass Index measure: Magnesium concentrations in the blood measure: Iron concentrations in the blood measure: Zinc concentrations in the blood sex: ALL minimumAge: 40 Years maximumAge: 60 Years stdAges: ADULT facility: Virginia Polytechnic Institute and State University status: RECRUITING city: Blacksburg state: Virginia zip: 24061 country: United States name: Stella L Volpe, PhD role: CONTACT phone: 540-231-3805 email: stellalv@vt.edu name: Alexandra Hanlon, PhD role: CONTACT phone: 540-231-5657 email: alhanlon@vt.edu lat: 37.22957 lon: -80.41394 hasResults: False
nctId: NCT06342011 id: KY-2024-039 briefTitle: Effect of Anti-inflammatory Diet in Patients With Inflammatory Bowel Disease overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-01 date: 2025-12-31 date: 2024-04-02 date: 2024-04-02 name: The Fourth Affiliated Hospital of Zhejiang University School of Medicine class: OTHER briefSummary: For the first time, this study developed an anti-inflammatory diet （AID） recipe suitable for Inflammatory bowel disease（IBD） patients and developed an AID application program to verify the intervention effect of AID on IBD patients, which not only promoted the application of AID in IBD patients and promoted the promotion of AID model, but also provided new ideas for the prevention and treatment strategies for IBD patients. conditions: Inflammatory Bowel Diseases studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: DOUBLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 88 type: ESTIMATED name: Anti-inflammatory diet group measure: C-reactive protein measure: Erythrocyte sedimentation rate (ESR) measure: Leukocyte measure: Self-Rating Anxiety Scale，SAS measure: Self-Rating depression scale，SDS measure: Simplified Chinese version of Inflammatory Bowel Disease Quality of Life Scale (IBDQ) measure: Inflammatory Bowel Disease Self-Efficacy Scale (IBD-SES) measure: Body Mass Index sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Fourth Affiliated Hospital of Zhejiang University School of Medicine city: Yiwu state: Zhejiang zip: 322000 country: China name: Xia Qian, BA role: CONTACT phone: 15968110117 email: 1632936247@qq.com lat: 29.31506 lon: 120.07676 hasResults: False
nctId: NCT06341998 id: HERO2020 briefTitle: Clinical Study of Chemotherapy in the Treatment of Recurrent/Refractory Yolk Sac Tumor in Children acronym: SCRRYST overallStatus: COMPLETED date: 2020-06-01 date: 2024-01-01 date: 2024-02-01 date: 2024-04-02 date: 2024-04-02 name: Shandong First Medical University class: OTHER briefSummary: Remarkable progress has been made in treating germ-cell tumor (GCT) through the use of platinum-based regimens. However, part of yolk sac tumor (YST) with cisplatin resistance or recurrence is nevertheless prone to relapse after second-line treatment. This leaves a gap in effective treatment, which needs to be filled by novel therapeutic approaches. This paper is the first one to report the treatment combining sirolimus with nab-paclitaxel, ifosfamide, and carboplatin (S-TIC) for children with repeated relapsed or refractory yolk sac tumor (rrrYST). conditions: Germ Cell Tumor conditions: Yolk Sac Tumor studyType: INTERVENTIONAL phases: PHASE2 phases: PHASE3 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 32 type: ACTUAL name: sirolimus combined with chemotherapy in the treatment of recurrent/refractory yolk sac tumor in children measure: Objective Response Rate Allocation 'Non-Randomized' implies that this is a multi-arm study, but only one arm has been specified. Objective Response Rate measure: Progression-free Survival sex: ALL minimumAge: 1 Year maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Shandong Cancer Hospital and Institute city: Jinan state: Shandong zip: 250117 country: China lat: 36.66833 lon: 116.99722 hasResults: False
nctId: NCT06341985 id: IEO 1593 briefTitle: DOsimetry and Radiation Induced NAusea in Head and Neck Cancers acronym: DORIAN overallStatus: RECRUITING date: 2021-11-15 date: 2024-11-15 date: 2024-12-31 date: 2024-04-02 date: 2024-04-02 name: European Institute of Oncology class: OTHER briefSummary: This is a prospective cohort study for the analysis of correlation between dosimetric parameters and RANV (Radiation Associated Nausea and Vomiting) in patients with head and neck cancer undergoing exclusive radiotherapy (RT).
nctId: NCT06341972 id: IRB00247005 id: K23HL155735 type: NIH link: https://reporter.nih.gov/quickSearch/K23HL155735 briefTitle: Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention acronym: SMARA overallStatus: NOT_YET_RECRUITING date: 2024-06-15 date: 2027-02-01 date: 2027-09-01 date: 2024-04-02 date: 2024-04-02 name: Johns Hopkins University class: OTHER name: Francis Family Foundation name: National Heart, Lung, and Blood Institute (NHLBI) briefSummary: A growing number of patients are surviving a stay in the intensive care unit (ICU) but may experience long-lasting psychological problems, but research evaluating such treatment for ICU patients is scant.
Participants will participate in a cognitive behavioral therapy informed self-management intervention aimed to reduce anxiety symptoms. Researchers will compare the intervention group to patients who receive usual care to see if the intervention reduces symptoms at the the conclusion of the intervention and at 3 months follow-up. conditions: Respiratory Failure conditions: Anxiety conditions: Critical Illness studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: pilot randomized controlled trial primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Cognitive behavioral therapy based self-management for anxiety measure: Treatment Satisfaction Questionnaire measure: average accrual rate of 2 patients/month across all patients measure: treatment feasibility as assessed by sessions completed measure: treatment feasibility as assessed by drop out rate measure: Visual Analog Scale - Anxiety measure: State Anxiety Inventory measure: Hopkins Rehab Engagement Scale measure: Self Efficacy for Managing Chronic Disease Rating Scale measure: Hospital Anxiety and Depression Scale measure: Quality of Life as assessed by the European Quality of Life Scale (EQ-5D) measure: Post Traumatic Stress Disorder as assessed by the Impact of Events Scale - 6 measure: Healthcare Utilization as assessed by Healthcare Utilization interview measure: Montreal Cognitive Assessment - Blind sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06341959 id: GerodentPLUS1 briefTitle: Can a Low-threshold Check-up Motivate Older People to Schedule a Dental Visit? overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-12-30 date: 2024-12-30 date: 2024-04-02 date: 2024-04-26 name: University Ghent class: OTHER briefSummary: There is little research on the effect of oral screening campaigns for improving oral health in older people. Therefore, the aim of this study is to investigate the effect of a low-threshold contact with an oral health professional, including an oral health examination, on dental attendance of older people (65 years of age or older). conditions: Oral Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The intervention group will be provided with tools to facilitate dental contact and will be informed about the importance of regular dental visits. Participants are given the opportunity to receive an oral examination. Afterwards, each participant will receive brochures with oral hygiene instructions to take home. Participants will receive information about any identified oral pathology. A referral letter for the dentist and a report for the general practitioner will also be prepared to increase social influence. If the participant doesn't have a dentist, the participant will receive a list of contact information for dentists in the area.
In the control group, no oral examination will be performed. However, participants will be given a list of nearby dentists and flyers with oral hygiene instructions. primaryPurpose: HEALTH_SERVICES_RESEARCH masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 194 type: ESTIMATED name: Oral screening measure: Contacted a dentist sex: ALL minimumAge: 65 Years stdAges: OLDER_ADULT typeAbbrev: Prot_SAP_ICF hasProtocol: True hasSap: True hasIcf: True label: Study Protocol, Statistical Analysis Plan, and Informed Consent Form date: 2024-03-25 uploadDate: 2024-03-25T05:59 filename: Prot_SAP_ICF_000.pdf size: 743439 hasResults: False
nctId: NCT06341946 id: Soh-Med-24-02-05MD briefTitle: Role of Endoscopic Third Ventriculostomy in Management of Malfunctioning Ventriculoperitoneal Shunt overallStatus: NOT_YET_RECRUITING date: 2024-04-05 date: 2025-10-01 date: 2025-11 date: 2024-04-02 date: 2024-04-02 name: Sohag University class: OTHER briefSummary: The aim of this study is to analyze our experience in management of malfunctioning ventriculoperitoneal shunt by using endoscopic third ventriculostomy (ETV). conditions: Hydrocephalus conditions: Shunt Malfunction studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: All patients with malfunctioning VP shunt will be included in this study primaryPurpose: TREATMENT masking: NONE count: 30 type: ESTIMATED name: Endoscopic third ventriculostomy measure: Glasgow Coma Scale (GCS) measure: visual analogue scale( VAS ) measure: visual acuity measure: radiological CT brain and or MRI brain sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06341933 id: 2024-BÇEK/41 briefTitle: Risk Factors for AKI in Patients Undergoing VATS for Pulmonary Resection overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2024-12-15 date: 2025-04-15 date: 2024-04-02 date: 2024-04-02 name: Atatürk Chest Diseases and Chest Surgery Training and Research Hospital class: OTHER briefSummary: This study aims to investigate the potential factors contributing to the development of Acute Kidney Injury (AKI) in patients undergoing pulmonary resection with Video Assisted Thoracoscopic Surgery (VATS) for lung malignancy. The study will focus on demographic data, laboratory parameters, perioperative fluid management, and haemodynamics.