hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06288880 id: kilis_4 briefTitle: Impact of Earthquake Trauma on Nurses' Compassion Fatigue: A Study From Kahramanmaraş, Turkey overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-04-01 date: 2024-05-01 date: 2024-03-01 date: 2024-03-01 name: Kilis 7 Aralik University class: OTHER name: Hasan Kalyoncu University briefSummary: This study investigates the impact of earthquake trauma on compassion fatigue among nurses working in emergency services following the devastating earthquakes on 6 February 2023, in Kahramanmaraş, Turkey. These earthquakes, with magnitudes of approximately 7.7 and 7.6, affected 11 provinces and resulted in over 50,000 deaths and 100,000 injuries, placing emergency service nurses at the forefront of dealing with the aftermath and trauma. The concept of compassion fatigue, characterised by a reduced capacity for empathy after repeated exposure to traumatic events, is a significant concern for nurses who have been directly involved in the care of earthquake victims. This study aims to explore the extent of earthquake trauma and compassion fatigue among these nurses, examining the relationship between these two conditions and their long-term effects. Given the limited research on post-traumatic stress disorder and compassion fatigue among emergency service nurses, this study seeks to contribute valuable insights into the psychological impacts of disaster response on healthcare professionals. The hypotheses tested aim to better understand the risks and psychological burdens faced by nurses in the wake of such natural disasters. conditions: Earthquake conditions: Compassion Fatigue studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 250 type: ESTIMATED measure: Section 1: Demographic Information Form measure: Section 2: Post-Earthquake Trauma Level Determination Scale measure: Section 3: Compassion Fatigue Short Scale sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Islam Elagöz city: Kilis zip: 79100 country: Turkey name: islam elagöz role: CONTACT name: Aynur koyuncu role: CONTACT lat: 36.71611 lon: 37.115 hasResults: False
nctId: NCT06288867 id: FMASU MD28/2024 briefTitle: A 12 Months Prospective Study Comparing Functional Outcome Scores in Hip Arthroscopic Labral Repair Versus Debridement overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-09-01 date: 2025-12-01 date: 2024-03-01 date: 2024-03-18 name: Ain Shams University class: OTHER briefSummary: This study aims to address hip labral tears and compare between arthroscopic labral repair versus debridement. conditions: Hip Injuries conditions: Acetabular Labral Tear conditions: Femoro Acetabular Impingement studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 20 type: ESTIMATED name: Arthroscopic Labral Repair name: Arthroscopic Labral Debridement measure: Change from baseline in Hip Function, as measured by Hip Outcome Score (HOS) measure: Change from baseline in Hip Function, as measured by Harris Hip Score (HHS) measure: Change from baseline in Pain, as measured by the Visual Analogue Scale (VAS) sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Ain Shams University city: Cairo country: Egypt name: Karim A Salem, MD role: CONTACT phone: 1000017388 phoneExt: +20 email: karimatefsalem@gmail.com lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06288854 id: 66222 briefTitle: Efficacy of Olanzapine on Weight Gain in Advanced Gynecologic Cancer With Paclitaxel and Carboplatin: a Double Blind, Placebo-controlled Randomized Trial overallStatus: NOT_YET_RECRUITING date: 2024-04-03 date: 2025-03-31 date: 2025-06-30 date: 2024-03-01 date: 2024-03-12 name: Rajavithi Hospital class: OTHER_GOV briefSummary: * Efficacy of olanzapine on weight gain in advanced stage gynecologic cancer
* Proprotion of pateints in advanced stage gynecologic cancer who recieving paclitaxel and carboplatin chemotherapy gain weight on olanzapine or placebo conditions: Weight Gain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: olanzapine vs placebo primaryPurpose: PREVENTION masking: SINGLE whoMasked: PARTICIPANT count: 48 type: ESTIMATED name: weight gain each group measure: Efficacy of olanzapine on weight gain in advanzed stage gynecologic cancer recieving paclitexal and carboplatin chemotherapy sex: FEMALE minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06288841 id: TJMZ2023-008 briefTitle: Efficacy and Safety of Liposomal Bupivacaine Under ERAS Concept for Postoperative Analgesia of Ultrasound-Guided QLB in Gynecologic Laparoscopic Patients: A Randomized, Single-blind, Active-Controlled Clinical Study overallStatus: RECRUITING date: 2023-11-30 date: 2024-07-31 date: 2024-11-29 date: 2024-03-01 date: 2024-03-01 name: Tianjin Medical University General Hospital class: OTHER briefSummary: With the development of the concept of comfortable medicine and enhanced recovery surgery (ERAS), optimizing the perioperative management of patients, reducing surgical stress, and reducing postoperative pain can effectively reduce perioperative complications and achieve the purpose of accelerating recovery. As an important part of ERAS, multimodal analgesia is the core concept of perioperative analgesia management. As a kind of perioperative multimodal analgesia, quadratus lumbar muscle block (QLB) is a type of local anesthetic drug injected around the quadratus lumbar muscle to reduce or eliminate abdominal wall pain and visceral pain after abdominal surgery. QLB has been used successfully for pain control after laparoscopic and open surgery, reducing perioperative opioid use and improving prognosis-related measures such as PONV and length of hospital stay. Bupivacaine liposomes use DepoFoam technology to encapsulate the drug in polycystic liposomes, which can prolong the release time of bupivacaine due to the different rupture times of different vesicles, and the postoperative analgesia can be up to 72 hours. In this project, patients who undergo elective laparoscopic uterine and double adnexectomy were selected to be injected with lipososomes of bupivacaine at different concentrations under ultrasound guidance of bilateral posterior QLB before anesthesia induction, and the effect of liposomal bupivacaine on postoperative pain was investigated by evaluating the postoperative pain and incidence of adverse events. This study will greatly promote the clinical promotion and application of bupivacaine liposome, improve the postoperative comfort and satisfaction of patients, and accelerate the postoperative recovery of patients. conditions: Pharmacological Action studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 200 type: ESTIMATED name: Ropivacaine injection name: Bupivacaine liposome measure: NRS pain score within 72 hours after surgery sex: FEMALE minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Tianjin Medical University General Hospital status: RECRUITING city: Tianjin state: Tianjin zip: 300052 country: China name: Ning Luo role: CONTACT phone: 13622098703 email: ningluo1996@163.com lat: 39.14222 lon: 117.17667 hasResults: False
nctId: NCT06288828 id: IRB0569/66 briefTitle: The Efficacy of Aerobic Exercise Training on Autonomic Nervous System and Endothelial Function in Patients With Compensated Cirrhosis overallStatus: NOT_YET_RECRUITING date: 2024-03-05 date: 2024-08-01 date: 2025-12-31 date: 2024-03-01 date: 2024-03-01 name: King Chulalongkorn Memorial Hospital class: OTHER name: Chulalongkorn University briefSummary: The goal of this clinical trial is to explore the impact of a 16-week aerobic exercise regimen on the autonomic nervous system and endothelial function in patients with compensated cirrhosis who maintain sedentary lifestyles. The primary research question is:
Participants in the intervention group will undergo 150 minutes of moderate aerobic exercise per week for 16 weeks, accompanied by a personalized nutritional plan (1.2 grams of protein per kilogram of ideal body weight per day and a calorie intake of 35 kilocalories per kilogram of ideal body weight per day). The control group will solely receive nutritional guidance and maintain their sedentary lifestyle. The researchers will compare outcomes between these two groups. conditions: Cirrhosis conditions: Aerobic Exercises conditions: Lifestyle Modification conditions: Endothelial Function conditions: Autonomic Nervous System conditions: Autonomic Dysfunction conditions: Heart Rate Variability conditions: Flow Mediated Dilation conditions: Sarcopenia conditions: Physical Activity conditions: Physical Functional Performance studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: INVESTIGATOR count: 70 type: ESTIMATED name: Aerobic exercise name: Nutrition consultant measure: Autonomic function test: Heart rate variability (HRV) measure: Endothelial function test: Flow mediated dilation (FMD) in % FMD change measure: Physical function measure: Muscle mass change measure: Muscle strength change sex: ALL minimumAge: 45 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Faculty of medicine, King Chulalongkorn Memorial Hospital city: Bangkok zip: 10330 country: Thailand lat: 13.75398 lon: 100.50144 hasResults: False
nctId: NCT06288815 id: TUH oral fluid TKA briefTitle: Oral Fluid vs IV Fluid After Primary TKA overallStatus: RECRUITING date: 2024-01-10 date: 2024-12 date: 2025-06 date: 2024-03-01 date: 2024-03-04 name: Thammasat University Hospital class: OTHER briefSummary: The goal of this study is to compared efficacy of oral fluid and intravenous fluid after primary unilateral total knee arthroplasty.
Does oral fluid replacement after primary unilateral total knee arthroplasty provide a patient recover faster than intravenous fluids replacement? conditions: Osteoarthritis, Knee conditions: Total Knee Arthroplasty conditions: Oral Fluid Replacement studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 130 type: ESTIMATED name: Oral fluid name: IV fluid measure: Time to stand and walk measure: Time up and go measure: Incidence of oliguria measure: Incidence of nausea/vomiting measure: Urine specific gravity measure: the levels of certain electrolytes measure: the levels of creatinine measure: the levels of blood urea nitrogen (BUN). measure: Complications sex: ALL minimumAge: 40 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Thammasat University status: RECRUITING city: Khlong Luang state: Pathum Thani zip: 12120 country: Thailand name: Yot Tanariyakul, M.D. role: CONTACT phone: 663930257 email: y.tanariyakul@gmail.com name: Nattapol Tammachote, M.D. role: PRINCIPAL_INVESTIGATOR lat: 14.06467 lon: 100.64578 hasResults: False
nctId: NCT06288802 id: 04-2023-200647 briefTitle: Study of Wilms Tumors Among Patients of Shefa Al-Orman Children Cancer Hospital overallStatus: RECRUITING date: 2020-06-15 date: 2024-06 date: 2024-12 date: 2024-03-01 date: 2024-03-01 name: South Egypt Cancer Institute class: OTHER name: Shefa Al-orman Children Cancer Hospital name: Assiut University briefSummary: The goal of this cross sectional observational study is to determine the percentage of Wilms tumors among pediatric cancers at Shefa Al-Orman Children Cancer Hospital from june 2020 to june 2024,to study the outcome of patients with Wilms tumor treated according to SIOP Umbrella protocol during the study period and to study the treatment related complications during therapy according to common terminology criteria of adverse events version 5.0 (CTCAE Version 5.0). conditions: Wilms Tumor studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 50 type: ESTIMATED measure: Overall-survival (OS) measure: Event-free survival (EFS) sex: ALL maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Shefa Al-orman Children Cancer Hospital status: RECRUITING city: Luxor country: Egypt name: Mahmoud Elzembely, MD role: CONTACT phone: +201146703107 email: elzimbily@aun.edu.eg lat: 25.69893 lon: 32.6421 hasResults: False
nctId: NCT06288789 id: SFI-TR briefTitle: Turkish Validity and Reliability of the Social Frailty Index overallStatus: COMPLETED date: 2024-02-25 date: 2024-03-20 date: 2024-03-30 date: 2024-03-01 date: 2024-04-25 name: Pamukkale University class: OTHER briefSummary: The aim was to examine the validity and reliability of the Social Frailty Index in Turkish among older adults. 65 years and above older adults will be included included in the study. Older adults who agree to participate in the study will first be administered the Hodkinson Mental Test. Those who score 6 points and above will be included in the study. To evaluate the validity of the \"Social Frailty Index\", Social Inclusion Scale, Older people\'s quality of life-brief (OPQOL-brief) and Lubben Social Network Scale will be applied to the participants. To determine the reliability of the \"Social Frailty Index\", older adults who do not receive any treatment will be tested and re-tested at one-week intervals. conditions: Elderly conditions: Frailty conditions: Quality of Life studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 186 type: ACTUAL name: Social Frailty Index measure: Social Frailty Index measure: Socıal Inclusıon Scale measure: Older people's quality of life-brief (OPQOL-brief) measure: Lubben Social Network Scale sex: ALL minimumAge: 65 Years stdAges: OLDER_ADULT facility: Elif Gur Kabul city: Usak state: Merkez zip: 64200 country: Turkey lat: 38.67351 lon: 29.4058 hasResults: False
nctId: NCT06288776 id: SOD/ERB/2023/22-04 briefTitle: Efficacy of Azadirachta Indica Based Herbal Mouthwash in Treating the Tooth Hypersensitivity overallStatus: COMPLETED date: 2023-02-01 date: 2023-04-30 date: 2023-04-30 date: 2024-03-01 date: 2024-03-01 name: Pakistan Institute of Medical Sciences class: OTHER_GOV briefSummary: Type of study: Single-blinded clinical trial to evaluate the effectiveness of Azadirachta indica based Herbal mouthwash to treat the tooth sensitivity in patients.
Participants aged 20 years and above having Gingival Index score 3 will be included in the study. Their tooth sensitivity will be checked initially and then they will be given Herbal based mouthwash for 3 months. Again, their tooth sensitivity shall be checked after 3 months. conditions: Tooth Sensitivity studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: In this study, participants will be selected by consecutive non-random sampling technique. primaryPurpose: TREATMENT masking: NONE maskingDescription: Single-blinded study where participant will be masked. count: 120 type: ACTUAL name: Herbal based mouthwash measure: Toothsensitivity declination with herbal based mouthwash sex: ALL minimumAge: 20 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Afsheen Mansoor city: Islamabad zip: 44080 country: Pakistan lat: 33.72148 lon: 73.04329 hasResults: False
nctId: NCT06288763 id: SC220192 briefTitle: Nerve Transfer to Improve Function in High Level Tetraplegia overallStatus: RECRUITING date: 2024-02-05 date: 2028-03-01 date: 2028-12-31 date: 2024-03-01 date: 2024-04-02 name: Washington University School of Medicine class: OTHER name: University of Michigan name: University of Calgary name: The Methodist Hospital Research Institute name: University of Pennsylvania name: University of Utah name: Stanford University name: University of Miami name: Johns Hopkins University name: University of Alberta briefSummary: The goal of this observational study is to determine if nerve transfer surgeries improve upper extremity function and quality of life in patients with a high level cervical spinal cord injury.
nctId: NCT06288750 id: sdllycyyqx001 briefTitle: Protective Effect of Indocyanine Green Fluorescence Imaging Technology on Parathyroid Glands During Total Thyroidectomy overallStatus: RECRUITING date: 2024-02-01 date: 2025-06-01 date: 2025-06-30 date: 2024-03-01 date: 2024-03-05 name: Shandong Linglong Yingcheng Hospital class: NETWORK briefSummary: Accurate identification and evaluation of the parathyroid glands (PGs) intraoperatively is critical to reduce the incidence of postoperative hypoparathyroidism after total thyroidectomy. Near-infrared fluorescence imaging (NIFI), including the autofluorescence (AF) and indocyanine green fluorescence (ICGF) imaging, is a promising technique to protect PGs. This study aimed to assess whether the combined use of AF and ICGF could reduce the incidence of postoperative hypoparathyroidism and improve the identification and evaluation of PGs during total thyroidectomy. conditions: Total Thyroidectomy conditions: Parathyroid Function Low Adverse Event conditions: Parathyroid Glands--Diseases conditions: Indocyanine Green studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: PREVENTION masking: DOUBLE whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 200 type: ESTIMATED name: Indocyanine Green name: No indocyanine green measure: Identification of parathyroid glands (PGs) by NIR/ICG camera detected high-contrast measure: Central lymph node dissetion (CLND) sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Shandong Linglong Yingcheng Hospital status: RECRUITING city: Yantai state: Shandong zip: 264000 country: China name: Xuan Qiu, MD role: CONTACT phone: 8618354280081 email: qiuxuan100@163.com name: Ni Wang, MD role: CONTACT phone: 8618705353551 email: wangni1989@163.com lat: 37.47649 lon: 121.44081 hasResults: False
nctId: NCT06288737 id: 54335073 briefTitle: Assessing Patient Engagement in Keratoconus Clinical Research overallStatus: NOT_YET_RECRUITING date: 2025-03 date: 2026-03 date: 2027-03 date: 2024-03-01 date: 2024-03-01 name: Power Life Sciences Inc. class: INDUSTRY briefSummary: This study aims to investigate the influences behind patient choices regarding involvement, discontinuation, or re-engagement in keratoconus clinical trials. Uncovering these factors is essential to enhance the relevance and efficacy of future research endeavors.
In essence, this trial aims to deepen understanding of the factors influencing participation in keratoconus clinical trials. Elevating participation rates could expedite the development of innovative treatments for this challenging condition. conditions: Keratoconus studyType: OBSERVATIONAL observationalModel: CASE_CROSSOVER timePerspective: PROSPECTIVE count: 500 type: ESTIMATED measure: Rate of patients who decide to join in a keratoconus clinical trial measure: Number of keratoconus patients who remain in clinical trial until completion sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Power Life Sciences city: San Francisco state: California zip: 94107 country: United States name: Michael B Gill role: CONTACT phone: 415-900-4227 email: https://www.withpower.com/contact-us@withpower.com lat: 37.77493 lon: -122.41942 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2024-02-23 uploadDate: 2024-02-23T11:13 filename: ICF_000.pdf size: 73995 hasResults: False
nctId: NCT06288724 id: NatIntensive briefTitle: MOdifiable facTors to Improve VentilAtion ThErapy in ICU acronym: MOTIVATE-ICU overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-09 date: 2024-09 date: 2024-03-01 date: 2024-03-01 name: Nat Intensive Care Surveillance - MORU class: OTHER name: D'Or Institute for Research and Education name: University of Oxford name: Wellcome Trust name: Makerere University briefSummary: ABSTRACT Introduction: Invasively ventilated patients in low and middle-income countries (LMICs) experience significantly higher mortality compared to those in High income countries (HICs). Direct application of HIC strategies to LMICs maybe ineffective due to context-specific challenges. This study aims to leverage the Intensive Care Registry of Uganda (ICRU) to identify ICU structural and process-related modifiable factors that impact patient outcomes in a low income country.
Methods: The MOTIVATE-ICU is a prospective multicentre observational study in invasively ventilated patients. It involves a registry-embedded component examining patient- and process-related factors and a cross-sectional survey on ICU organizational structures. Inclusion criteria encompass patients aged ≥ 15 years undergoing IMV in Ugandan ICUs. Primary outcomes are ICU mortality, ICU length of stay (LOS), and duration of ventilation. Secondary outcomes include ventilator-associated complications, non-pulmonary organ support. tTracheostomy outcomes will be explored in a pre-planned substudy. Factors potentially associated with outcomes will be categorized into two groups; non-modifiable factors and potentially modifiable. Non-modifiable factors will include patient-related factors like age, comorbidities and illness severity; potentially modifiable factors include processes of care (e.g. sedation levels) and ICU organizational structure (e.g. staffing patterns). Multilevel multivariable logistic regression will be utilized to study associations, with both patient and ICU level fixed effects considered.
Ethics and Dissemination: Given its observational nature, this study seeks a waiver for patient individual informed consent. Data anonymization ensures patient privacy. Following the principles of the Declaration of Helsinki, relevant ethical approvals will be acquired. Study findings will be disseminated through conferences and peer-reviewed journals. conditions: Critical Illness conditions: Invasive Mechanical Ventilation conditions: ICU Mortality conditions: Developing Countries conditions: Risk Factors studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 625 type: ESTIMATED measure: ICU mortality measure: ICU Length of Stay measure: Duration of mechanical ventilation measure: Duration of non-pulmonary organ support measure: ICU-Free days measure: Ventilator-free days measure: Ventilator-associated Pneumonia measure: Tracheobronchitis measure: Non-infectious Pulmonary complication measure: Readmission measure: Unplanned extubations measure: Tracheostomy related outcomes sex: ALL minimumAge: 15 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False