hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06279156 id: MTU-EC-IM-0-014/65 briefTitle: Optimal Frequency of Total Body Water Measurements by Bioelectrical Impedance Analysis to Prevent Intradialytic Hypotension overallStatus: COMPLETED date: 2022-06-01 date: 2023-02-28 date: 2023-02-28 date: 2024-02-26 date: 2024-03-06 name: Thammasat University Hospital class: OTHER briefSummary: The goal of this clinical trial was to compare the efficiencies of bioelectrical impedance analysis (BIA) measurement frequency in preventing intradialytic hypotension in end-stage renal disease (ESRD) patients undergoing regular hemodialysis. The main question aimed to answer about the optimum frequency of BIA measurements to prevent intradialytic hypotension.
Researchers compared the efficiencies of BIA measurements between the every-1-month group and the every-2-month group to prevent intradialytic hypotension. conditions: Intradialytic Hypotension conditions: End Stage Renal Disease on Dialysis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: PREVENTION masking: NONE count: 94 type: ACTUAL name: Bioelectrical Impedance Analysis (BIA) measure: incidence rate ratio of intra-dialytic hypotension of every-1-month BIA to every-2-month BIA measure: factors affecting intra-dialytic hypotension sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Thammasat University Hospital city: Pathum Thani zip: 12120 country: Thailand lat: 14.01346 lon: 100.53049 hasResults: False
nctId: NCT06279143 id: dOCT-pBCC briefTitle: The Diagnostic Accuracy of Advanced Imaging in Identifying Suspected Skin Cancer (Basal Cell Carcinoma) Around the Eyes acronym: dOCT-pBCC overallStatus: RECRUITING date: 2024-04-04 date: 2026-08-31 date: 2026-11-30 date: 2024-02-26 date: 2024-04-25 name: Vejle Hospital class: OTHER briefSummary: The purpose is to investigate the diagnostic value (sensitivity and specificity) of dermal-Optical Coherence Tomography (D-OCT, VivoSight Dx), in patients with clinically suspected BCC lesions inside the periocular region and compare these results to previous reports using D-OCT in diagnosing lesions outside the periocular area.
* Delineation of periocular BCC tumour extension is possible using both D-OCT probes conditions: BCC - Basal Cell Carcinoma conditions: BCC conditions: Skin Diseases conditions: Eyelid Tumor conditions: Eyelid Diseases studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 210 type: ESTIMATED measure: Diagnostic accuracy of D-OCT in diagnosing BCC inside the periocular region, compared to previous reports on lesions outside the periocular region measure: Comparative diagnostic accuracy of D-OCT´s standard vs customized probe for diagnosing BCC measure: Comparative diagnostic accuracy of D-OCT´s standard vs customized probe for subtyping BCC measure: Observer agreement in identifying presence/absence of BCC lesions, using D-OCT measure: Observer agreement in classifying BCC lesions into subtypes, using D-OCT measure: Observer agreement in mapping BCC lesions prior to surgery, using D-OCT measure: Quantification of learning curve in correctly diagnosing BCC over time with increasing experience with D-OCT measure: Quantification of learning curve in correctly identifying BCC subtypes over time with increasing experience with D-OCT measure: Quantification of skills in correctly demarcating BCC over time with increasing experience with D-OCT measure: Accuracy of D-OCT in delineation of periocular BCC extension prior to surgery sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Ophthalmology, University Hospital of Southern Denmark, Vejle Hospital status: RECRUITING city: Vejle state: Region Of Southern Danmark zip: 7100 country: Denmark name: Sveina B Karlsdóttir, MD role: CONTACT phone: 53420448 phoneExt: 0045 email: sveina@outlook.dk name: Susanne Støvring role: CONTACT phone: 79406461 phoneExt: 0045 email: susanne.stoevring@rsyd.dk lat: 55.70927 lon: 9.5357 hasResults: False
nctId: NCT06279130 id: N23NEO briefTitle: Pan-tumor Neoadjuvant Basket Study of Immune Check-point Inhibition and Novel Immuno-oncology Combinations acronym: NEOASIS overallStatus: RECRUITING date: 2024-01-29 date: 2029-01-29 date: 2034-01-29 date: 2024-02-26 date: 2024-02-26 name: The Netherlands Cancer Institute class: OTHER name: Agenus Inc. briefSummary: In this study, the efficacy of botensilimab and balstilimab in mismatch repair deficient (dMMR) and mismatch repair proficient (pMMR) tumors will be assessed. conditions: Resectable MMR-deficient Solid Tumors conditions: Resectable MMR-proficient Solid Tumors studyType: INTERVENTIONAL phases: PHASE2 phases: PHASE3 allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Basket, open-label primaryPurpose: TREATMENT masking: NONE count: 92 type: ESTIMATED name: botensilimab name: balstilimab measure: Major pathological response rate measure: Pathological response rates measure: Event free survival measure: Disease free survival measure: Overall survival measure: Radiological response sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Netherlands Cancer Institute status: RECRUITING city: Amsterdam state: Noord-Holland zip: 1066 CX country: Netherlands name: Marieke van de Belt, MsC role: CONTACT name: Myriam Chalabi, MD PhD role: PRINCIPAL_INVESTIGATOR lat: 52.37403 lon: 4.88969 hasResults: False
nctId: NCT06279117 id: 2023/9/8 briefTitle: The Effect of Therapeutic Touch on Exam Anxiety overallStatus: RECRUITING date: 2024-01-15 date: 2024-02-23 date: 2024-03-10 date: 2024-02-26 date: 2024-02-26 name: Dokuz Eylul University class: OTHER briefSummary: Aim: This study was planned to determine the effect of therapeutic touch applied to nursing students on test anxiety.
Method: Students who met the inclusion criteria were divided into therapeutic touch and control groups using the randomization method. After the groups were determined, the students filled out the Introductory Information Form and the State Exam Anxiety Scale. 30 minutes before the exam, therapeutic touch was applied to each of the students, who were divided into groups, for 20 minutes. No application was made to the control group, and they were told to wait in the classroom where the group was waiting as they wished.Immediately after the application was completed, the scale was re-applied to both groups. conditions: Test Anxiety studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomised controlled clinical trial primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: PARTICIPANT count: 50 type: ESTIMATED name: therapeutic touch measure: Text Anxiety measure: Text Anxiety sex: ALL minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT facility: Gizem Göktuna status: RECRUITING city: İzmir zip: 35000 country: Turkey name: Gizem Göktuna role: CONTACT phone: +905448303393 email: gizemgoktuna@gmail.com lat: 38.41273 lon: 27.13838 hasResults: False
nctId: NCT06279104 id: 2023-TJ-OCCC briefTitle: A Comparative Study of the Treatment of Real-world Patients With Clear Cell Carcinoma of the Ovary overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-05-01 date: 2025-05-01 date: 2024-02-26 date: 2024-02-26 name: Tongji Hospital class: OTHER name: Wuhan Union Hospital, China name: Henan Cancer Hospital name: Qilu Hospital of Shandong University name: Hubei Cancer Hospital name: Anhui Provincial Cancer Hospital name: Peking University Cancer Hospital & Institute name: Hunan Province Tumor Hospital name: First Affiliated Hospital of Suzhou Medical College name: Shandong Tumor Hospital name: Chongqing University Cancer Hospital name: First Affiliated Hospital of Zhongshan Medical University name: Peking University Shenzhen Hospital briefSummary: The goal of this observational study is to learn about the treatment effectiveness of physician's choice of chemotherapy and the immune checkpoint inhibitor (ICI)-based therapy in patients with relapsed/refractory ovarian clear cell carcinoma (OCCC), and compare the treatment response with the phase II, single-arm clinical trial INOVA to investigate the efficacy of combinational therapy of sintilimab plus bevacizumab. The main questions it aims to answer are:
Participants will be respectively retrieved and extracted de-identified, longitudinal electronic health records (EHR)-derived data. conditions: Ovarian Clear Cell Carcinoma studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: RETROSPECTIVE count: 150 type: ESTIMATED name: physician's choice of chemotherapy name: immune checkpoint inhibitor based therapy measure: tumor response rate measure: progression-free survival (PFS) measure: time to response (TTR) measure: duration of response (DOR) measure: disease control rate (DCR) sex: FEMALE minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06279091 id: A0104023PP briefTitle: Correlation of Children and Parental Anxiety and Effectiveness of Breathing Exercises on Anxiety Reduction overallStatus: ACTIVE_NOT_RECRUITING date: 2023-05-23 date: 2023-11-05 date: 2024-05-23 date: 2024-02-26 date: 2024-02-26 name: Mansoura University class: OTHER briefSummary: The purpose of this study to evaluate the correlation between children and parental dental anxiety as well as to evaluate the effectiveness of breathing exercises on anxiety reduction. conditions: Dental Anxiety studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Selected children will be divided randomly into 3 groups:
Control group (Group I). Diaphragmatic Breathing group (Group II). Bubble Blower Breathing group (Group III). primaryPurpose: OTHER masking: NONE count: 90 type: ESTIMATED name: Diaphragmatic Breathing name: Bubble Blower Breathing name: Tell Show Do measure: scale of dental anxiety by Corah Dental Anxiety Scale (CDAS) measure: scale of dental anxiety by Facial Image Scale (FIS) measure: scale of dental anxiety by Venham Clinical Anxiety Scale (VCAS) measure: scale of dental anxiety by Pulse Oximeter sex: ALL minimumAge: 5 Years maximumAge: 8 Years stdAges: CHILD facility: Mansura University city: Mansoura state: Dakahlia zip: 35511 country: Egypt lat: 31.03637 lon: 31.38069 hasResults: False
nctId: NCT06279078 id: AJOUIRB-DB-2023-446 briefTitle: Long-term Effect of Steroid on Metabolic Diseases in Asthmatics overallStatus: RECRUITING date: 2023-12-30 date: 2024-12-30 date: 2025-06-30 date: 2024-02-26 date: 2024-02-26 name: Ajou University School of Medicine class: OTHER name: AstraZeneca briefSummary: The goal of this retrospective/observational study is to compare the clinical outcomes between the high-cumulative-dose group and the low- cumulative-dose group of oral/inhaled corticosteroid in the long-term management of asthma patients. The main hypothesis are:
iv. High cumulative dose of corticosteroid affects bone metabolism-related diagnostic tests and laboratory values and the prescription rate of bone metabolism-related medications. conditions: Asthma conditions: Osteoporosis, Osteopenia conditions: Osteoporosis Risk conditions: Osteoporotic Fractures studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 20000 type: ESTIMATED name: Corticosteroid measure: Prevalence of osteoporosis/osteopenia measure: Bone mineral density (BMD) score measure: Total alkaline phosphatase measure: Corrected calcium measure: Serum phosphate measure: Serum albumin measure: prevalence of steroid related comorbidities(Diabetes Mellitus, Hypertension, Hyperlipidemia, etc.) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ajou University Medical Center status: RECRUITING city: Suwon state: Gyeonggi zip: 16499 country: Korea, Republic of name: Hyun-Seob Jeon, M.D. role: CONTACT phone: +82-31-219-4612 email: googlingpenguin@gmail.com name: Hae-Sim Park, M.D., Ph.D. role: CONTACT phone: +82-31-219-4779 email: hspark@ajou.ac.kr lat: 37.29111 lon: 127.00889 hasResults: False
nctId: NCT06279065 id: 373/23-EP briefTitle: Investigation of the Influence of the Human Microbiome on the Pathogenesis and Recurrence Probability in Giant Cell Arteritis acronym: GCA-Biom overallStatus: RECRUITING date: 2024-02-18 date: 2026-02-18 date: 2028-02 date: 2024-02-26 date: 2024-02-26 name: University of Bonn class: OTHER briefSummary: The longitudinal observational study aims to assess the impact of the microbiome especially the gut-microbiome in the emergence and course of giant cell arteritis (GCA) patients. At diagnosis and 6 month follow up we will analyze the oral, blood and gut microbiome from GCA patients and healthy controls. Thereby identified potential candidate commensal will be further analyzed for possible interactions and influence on the immune system. conditions: Giant Cell Arteritis studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 50 type: ESTIMATED name: Analysis of blood and microbiome samples (stool, oral lavage) measure: Significant differences in the composition of the microbiome measure: Influence of the microbiome on therapy response e.g. increased probability of recurrence with accumulation of specific microbiome species measure: potential association of microbiom composition with application of immune modulating drugs sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Clinic of Internal Medicine III, Department of Oncology, Haematology, Rheumatology and Clinical Immunology, University Hospital Bonn status: RECRUITING city: Bonn state: North Rhine-Westphalia zip: 53127 country: Germany name: Valentin S. Schäfer, Dr. med. role: CONTACT phone: +49 228 287-17000 email: rheumatologie@ukbonn.de lat: 50.73438 lon: 7.09549 facility: University Hospital Bonn status: RECRUITING city: Bonn zip: 53127 country: Germany name: Valentin Schäfer, MD role: CONTACT phone: +28 287 17000 email: rheumatologie@ukbonn.de name: Maike Adamson role: CONTACT phone: +28 287 17000 email: rheumatologie@ukbonn.de lat: 50.73438 lon: 7.09549 hasResults: False
nctId: NCT06279052 id: RC31/23/0535 briefTitle: Adolescent Projections During Transition in Prader-Willi Syndrome acronym: APT-WILL overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-12-01 date: 2024-12-01 date: 2024-02-26 date: 2024-02-28 name: University Hospital, Toulouse class: OTHER briefSummary: Single-center, cross-sectional qualitative study seeking to collect the experience of adolescence and the transition to adulthood of people affected by Prader-Willi syndrome in a population. To do this, the present will carry out a qualitative study with a reflexive thematic analysis of the data collected through semi-structured interviews using an interview guide. conditions: Prader-Willi Syndrome studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 20 type: ESTIMATED name: Phone interview measure: Experience of the disease and aspirations regarding the future sex: ALL minimumAge: 15 Years maximumAge: 20 Years stdAges: CHILD stdAges: ADULT facility: CHU de Toulouse city: Toulouse country: France name: Grégoire BENVEGNU role: CONTACT email: benvegnu.g@chu-toulouse.fr name: Dalil Benkanoun role: CONTACT email: dalil.benkanoun@hotmail.fr lat: 43.60426 lon: 1.44367 hasResults: False
nctId: NCT06279039 id: KY20230116-06 briefTitle: Clinical Observation of Exosomes in Patients After Q-switched Laser Surgery overallStatus: RECRUITING date: 2022-09-01 date: 2024-08-31 date: 2024-12-31 date: 2024-02-26 date: 2024-02-26 name: Nanjing First Hospital, Nanjing Medical University class: OTHER briefSummary: the goal of this half-face controlled study is to evaluate the effect of exosome-containing liquid dressings on the recovery of patients after Nd:YAG laser 532 treatment. conditions: Exosome conditions: Skin Regeneration conditions: Laser studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 38 type: ESTIMATED name: Exosome liquid dressing measure: Global Aesthetic Improvement Scale score measure: Dermatology Quality of life index measure: post-inflammatory hyperpigmentation sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Jie Dai status: RECRUITING city: Nanjing state: Jiangsu zip: 210006 country: China name: jie dai role: CONTACT phone: 02552271117 email: karry_dj@126.com lat: 32.06167 lon: 118.77778 hasResults: False
nctId: NCT06279026 id: PG-006-5 briefTitle: UTAA17 Injection in the Treatment of Relapsed/Refractory Multiple Myeloma overallStatus: RECRUITING date: 2024-04-01 date: 2027-04-01 date: 2027-07-01 date: 2024-02-26 date: 2024-02-26 name: PersonGen BioTherapeutics (Suzhou) Co., Ltd. class: INDUSTRY name: Second Affiliated Hospital of Soochow University briefSummary: The clinical trial was designed as a single-arm, open-label clinical study, with the main purpose of exploring the safety, pharmacokinetics, and best recommended dose (RP2D) of the UTAA17 injection in the treatment of relapsed or refractory multiple myeloma (r/r MM) subjects, and also the efficacy will be observed. Eligible subjects will accept the infusion of UTAA17 injection after pretreatment, and their blood will be collected before and after infusion for evaluation of pharmacokinetics, immunogenicity and safety. This study plans to evaluate efficacy using the revised Evaluation of Efficacy in multiple myeloma -IMWG criteria (2016), which will be evaluated at 4w, 2m, 3m, 6m, and 6 to 24m (at a frequency of Q3m) after cell reinfusion, in addition to the baseline period. Efficacy evaluation continues until one of the following occurs: subject disease progression (PD), acceptance of a new antitumor therapy, death, occurrence of intolerable toxicity, investigator decision, or patient decision to withdraw. conditions: Relapsed/Refractory Multiple Myeloma studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: UTAA17 injection primaryPurpose: TREATMENT masking: NONE count: 15 type: ESTIMATED name: UTAA17 Injection measure: DLT measure: RP2D sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Second Affiliated Hospital of Soochow University status: RECRUITING city: Suzhou state: Jiangsu zip: 215000 country: China name: Huimin Meng, doctor role: CONTACT phone: +86-18015580390 email: huimin.meng@persongen.com.cn lat: 31.30408 lon: 120.59538 hasResults: False
nctId: NCT06279000 id: CTU 22/025 briefTitle: Colchicine in Patients at Cardiac Risk Undergoing Major Non-Cardiac Surgery acronym: COLCAT overallStatus: NOT_YET_RECRUITING date: 2024-10-01 date: 2027-09-30 date: 2028-09-30 date: 2024-02-26 date: 2024-02-28 name: Cantonal Hospital of St. Gallen class: OTHER briefSummary: Perioperative myocardial injury/infarction (PMI) and major adverse cardiovascular events (MACE) are common causes of morbidity and mortality in patients at increased cardiovascular risk undergoing non-cardiac surgery.
These encouraging results in non-surgical patients ask for a similar investigation in patients undergoing major non-cardiac surgery. The aim of the proposed study is to investigate the effects of perioperative colchicine administration on the incidence of PMI/MACE. conditions: Cardiovascular Diseases conditions: Cardiovascular Complication conditions: Perioperative Complication conditions: Myocardial Infarction studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: randomized, triple-blinded, placebo-controlled, multicenter primaryPurpose: TREATMENT masking: QUADRUPLE maskingDescription: Patients, anaesthesia providers and all other health care workers involved in the treatment and the study personal will be blinded to the group allocation by provision of equal looking study drugs (verum and placebo), which are repacked for blinding. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 880 type: ESTIMATED name: Colchicine name: Placebo measure: Perioperative Myocardial Injury/Infarction measure: Major Adverse Cardiovascular Events measure: New onset Atrial fibrillation measure: postoperative high sensitive cardiac Troponin T concentrations measure: long term cardiovascular outcome measure: Gastrointestinal adverse events sex: ALL minimumAge: 45 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06278987 id: ANES-2024-32661 briefTitle: Comparison of Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter in Patients With a Hip Fracture overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2026-06-01 date: 2026-12-01 date: 2024-02-26 date: 2024-03-19 name: University of Minnesota class: OTHER briefSummary: The purpose of this study is to determine if patients with hip fractures who undergo cryoablation of the PENG have improved pain control 30 days from surgery when compared to those who have a fascia iliaca catheter. conditions: Hip Fractures studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: This is a randomized prospective controlled trial. This will be single blinded trial. Randomization will be 1:1 primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 150 type: ESTIMATED name: PENG block and cryoablation name: fascia iliaca compartment block measure: Maximum pain score on Post-operative day 30 measure: Opioid use measure: functional pain scores measure: number of patients using opioids measure: Length of Hospital Stay measure: Time to first ambulation measure: Number of patients returned home by Post Operative Day 30 sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06278974 id: PDSFGOCLMC-2023-001 briefTitle: Comparing Myopia Treatments in Youth: Defocus Spectacles, Glasses, and Ortho-K overallStatus: RECRUITING date: 2023-11-10 date: 2025-05-01 date: 2025-05-01 date: 2024-02-26 date: 2024-02-26 name: He Eye Hospital class: OTHER briefSummary: The research project titled "A Comparative Study on the Clinical Efficacy, Quality of Life, and Cost of Use of Peripheral Defocus Spectacles, Frame Glasses, and Orthokeratology Lenses in Myopic Children and Adolescents" aims to evaluate different non-surgical myopia correction methods in children. It focuses on assessing the impact of peripheral defocus spectacles, frame glasses, and orthokeratology lenses on the quality of life, clinical effectiveness, and costs associated with each method. The study is a prospective cohort study involving 300 children aged 13-17 years with myopia ranging from -1.00D to -6.00D. It aims to compare the psychological, social, and educational aspects of these correction methods, alongside their costs and clinical outcomes over a period of one year. conditions: Myopia conditions: Cost-effectiveness Analysis conditions: Quality of Life studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 300 type: ESTIMATED measure: Improvement in Quality of Life Scores measure: Cost-Effectiveness Analysis measure: Clinical Effectiveness Analysis sex: ALL minimumAge: 13 Years maximumAge: 17 Years stdAges: CHILD facility: HeEyeHospital status: RECRUITING city: Shenyang state: Liaoning zip: 110000 country: China name: Lan Hu, Master role: CONTACT phone: 15940406919 email: hulan@hsyk.com.cn lat: 41.79222 lon: 123.43278 hasResults: False