hackint0sh/New-Dataset huggingface dataset:
Over eighteen months, 124 outpatients beginning H\&NC radiotherapy at Forcilles's Hospital will undergo weekly clinical and water-swallow tests by a speech language therapist, with videofluoroscopy when SD is suspected. Ultrasound evaluations pre-treatment and at seven and fourteen days will be conducted by blinded ultrasonographers. Cox models will test ultrasound measurement thresholds for SD prediction, estimating sensitivity, specificity, and prediction values. A global ultrasound predictive model will be developed via logistic multivariable regression.
The study aims to establish an association between ultrasound markers and SD, improving early detection for tailored management. This non-invasive alternative to videofluoroscopy offers potential for enhancing patient outcomes in H\&NC radiotherapy. conditions: Swallowing Disorders studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 112 type: ESTIMATED measure: The primary endpoint is the predictive ability of morphology and/or movement of the tongue, hyoid bone and suprahyoid muscles measured by ultrasound on the occurrence of TDs during radiotherapy. measure: Inter and intra-rater evaluation measure: Predictive capacity of observed changes in ultrasound to anticipate swallowing disorders development measure: Predictive capacity of ultrasound markers measured at inclusion on the incidence of undernutrition during radiotherapy. measure: Predictive capacity of observed changes in ultrasound to anticipate incidence of undernutrition or nutritional status evolution during radiotherapy. measure: Predictive capacity of ultrasound markers for anticipating quality of life assessed by the MD Anderson Dysphagia Inventory questionnaire at 30 days of radiotherapy treatment measure: Ratio of ultrasound measurements of tongue, hyoid bone, and suprahyoid muscle morphology and/or movement successfully conducted sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hôpital Forcilles status: RECRUITING city: Férolles-Attilly zip: 77150 country: France name: Aymeric Le Neindre, PhD role: CONTACT phone: +33160646093 email: aleneindre@cognacq-jay.fr name: Carlos DIAZ LOPEZ, MSc role: PRINCIPAL_INVESTIGATOR lat: 48.73184 lon: 2.63088 hasResults: False
nctId: NCT06386991 id: 2024/206 briefTitle: Effect of Different Irrigation Solutions on Postoperative Pain and Lesion Healing overallStatus: RECRUITING date: 2024-01-01 date: 2024-08-01 date: 2026-01-01 date: 2024-04-26 date: 2024-04-26 name: TC Erciyes University class: OTHER briefSummary: In this study researchers plan to conduct, three different irrigation solutions that are responsible for the release of growth factors necessary for the success of regenerative endodontic treatments will be used. These solutions; Ethylene Diamine Tetra Acetic Acid (EDTA), Etidronic Acid and Citric Acid. The aim of this study is to evaluate the effect of different irrigation solutions used in regenerative endodontic treatment of necrotic open apex molar teeth on postoperative pain. Additionally, the healing of these teeth will be monitored for 1 year. conditions: Endodontic Disease studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 39 type: ESTIMATED name: Using ethylenediaminetetraacetic acid (EDTA), citric acid ((MONO/ANH) and etidronic acid (HEBP) to clean root canals during regenerative endodontic treatments measure: Determining and recording pain levels on the pain scale between treatment sessions measure: In the follow-up sessions after the treatment, the size of the lesion in the bone (mm2) is measured by radiography. sex: ALL minimumAge: 8 Years maximumAge: 15 Years stdAges: CHILD facility: Erciyes Üniversitesi Diş Hekimliği Fakültesi status: RECRUITING city: Kayseri zip: 38039 country: Turkey name: ERASLAN AKYÜZ role: CONTACT phone: 4447138 phoneExt: 0352 email: ipekemamak@hotmail.com name: ÜSTÜN role: CONTACT phone: 4447138 phoneExt: 0352 email: yustun@erciyes.edu.tr lat: 38.73222 lon: 35.48528 hasResults: False
nctId: NCT06386978 id: 2024/209 briefTitle: Analgesic Efficacy of Transvers Abdominis Plane Block and Transversalis Fascia Plane Block in Cesarean Section overallStatus: RECRUITING date: 2024-05-30 date: 2025-05-30 date: 2026-05-30 date: 2024-04-26 date: 2024-04-26 name: TC Erciyes University class: OTHER briefSummary: This study was designed as a prospective, randomized observational clinical trial.
TAP Block Group (n=30,Group 1): Spinal Anesthesia + TAP block ; TFP Block group (n=30,Group 2): Spinal Anesthesia + TFP block ; Control group (n=30,Group 3); Spinal Anesthesia + No block; conditions: Obstetric studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 90 type: ESTIMATED name: Transverse Facia Plane Block (TAP Block) name: Transversalis Facia Plane Block (TFP Block) name: Control measure: VAS score evaluation measure: time until the first analgesic request measure: Satisfaction/Dissatisfaction sex: FEMALE minimumAge: 18 Years maximumAge: 49 Years stdAges: ADULT facility: Erciyes University status: RECRUITING city: Kayseri zip: 38039 country: Turkey name: Kudret Dogru, Prof role: CONTACT phone: +905334735112 email: kdogru@erciyes.edu.tr name: Sibel Pehlivan, Asssoc Prof. role: CONTACT phone: +905052532919 email: sibelpehlivan@erciyes.edu.tr lat: 38.73222 lon: 35.48528 hasResults: False
nctId: NCT06386965 id: 010.99/15 briefTitle: Sevoflurane Versus Propofol: Effect on Stress Response overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-05 date: 2024-06-05 date: 2024-06-05 date: 2024-04-26 date: 2024-04-26 name: Dr. Lutfi Kirdar Kartal Training and Research Hospital class: OTHER_GOV briefSummary: Stress is defined as hormonal and metabolic changes in the biological system that follow any injury. The stress response occurs as a general systemic response to injury and includes a wide range of endocrinological, immunological and hematological effects. The level of stress in the surgical process can affect not only the patients outcome but also the overall health system.
The aim of investigators' for this study was to investigate the effect of different anesthetic agents on stress inflammatory response in the preoperative, peroperative and postoperative periods. conditions: Propofol conditions: Sevoflurane conditions: Inflammatory Response studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 40 type: ESTIMATED name: taking blood sample measure: compare inflammatory markers with sevolurane and propofol : glucose, WBC, procalcitonin, CRP, erytrocyte sedimentation rate, ferritin, pre albumin, albumin,tranferrin sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Health Science, Kartal Dr Lutfi Kırdar Training and Researh Hospital city: İstanbul country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06386952 id: 02/2024-2025 briefTitle: To Compare People With T2DM Who Have Double Hump Versus Who do Not Have Double Hump overallStatus: RECRUITING date: 2024-05-01 date: 2025-05-31 date: 2025-06-30 date: 2024-04-26 date: 2024-04-26 name: Diabetes Foundation, India class: OTHER name: National Diabetes Obesity and Cholesterol Foundation briefSummary: Hypothesis: Double Hump in people with T2D is associated with higher magnitude of complication than people with single hump or no hump
3. CVS-Stroke/ TIA/Carotid Blockage \>50% conditions: Type 2 Diabetes Mellitus With Complication studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 200 type: ESTIMATED measure: Double Hump increases diabetes complications sex: ALL minimumAge: 20 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Anoop misra status: RECRUITING city: New Delhi state: Delhi zip: 110048 country: India name: Anoop Misra, MD role: CONTACT phone: 01149101222 email: anoopmisra@gmail.com name: Koel Dutta, M.Sc role: CONTACT phone: 01149101222 email: koelduttac@gmail.com name: Anoop Misra, MD role: PRINCIPAL_INVESTIGATOR name: Koel Dutta, M.Sc role: SUB_INVESTIGATOR lat: 28.63576 lon: 77.22445 hasResults: False
nctId: NCT06386939 id: 01/2024-2025 briefTitle: Comparison of Micro- and Macrovascular Disease(s) in People With T2D, Who Have Moderate to Severe Acanthosis Nigricans vs. Those Who do Not Have Acanthosis Nigricans overallStatus: RECRUITING date: 2024-05-01 date: 2025-10-30 date: 2025-11-30 date: 2024-04-26 date: 2024-04-26 name: Diabetes Foundation, India class: OTHER name: National Diabetes Obesity and Cholesterol Foundation briefSummary: Hypothesis: Moderate to severe acanthosis nigricans in people with T2D is associated with higher magnitude of complication than people who do not have acanthosis nigricans.
3. CVS-Stroke/ TIA/Carotid Blockage \>50% conditions: Type 2 Diabetes Mellitus With Complication studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: OTHER count: 300 type: ESTIMATED measure: Moderate to Severe Acanthosis Nigricans increases diabetes complications sex: ALL minimumAge: 20 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Anoop misra status: RECRUITING city: New Delhi state: Delhi zip: 110048 country: India name: Anoop Misra, MD role: CONTACT phone: 01149101222 email: anoopmisra@gmail.com name: Koel Dutta, M.Sc role: CONTACT phone: 01149101222 email: koelduttac@gmail.com name: Anoop Misra, MD role: PRINCIPAL_INVESTIGATOR name: Koel Dutta, M.Sc role: SUB_INVESTIGATOR lat: 28.63576 lon: 77.22445 hasResults: False
nctId: NCT06386926 id: P.T.REC/012/005075 briefTitle: Radial Shockwave Versus Ultrasound Phonophoresis overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-07 date: 2024-09 date: 2024-04-26 date: 2024-04-26 name: Cairo University class: OTHER briefSummary: Comparative study to compare the effect of radial shockwave versus ultrasound phonophoresis in management of chronic supraspinatus tendinitis consists of 3 groups exp1(shockwave treatment + conventional physical therapy) , exp2( ultrasound phonophoresis+ conventional physical therapy) and control group ( conventional physical therapy) conditions: Supraspinatus Tendinitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 69 type: ESTIMATED name: Electro Therapy measure: change in the thickness of supraspinatus tendon measure: change in pain intesity measure: Change in shoulder range of motion measure: Function of the Upper Limb measure: measure weight in kg and height in cm sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Cairo university city: Giza country: Egypt name: Shady Alkadry role: CONTACT lat: 30.00808 lon: 31.21093 hasResults: False
nctId: NCT06386913 id: IRB-20-1065 briefTitle: Implementation and Evaluation of Measurement-Based Care (MBC) Training overallStatus: ACTIVE_NOT_RECRUITING date: 2021-02-09 date: 2024-06-30 date: 2024-12-31 date: 2024-04-26 date: 2024-04-26 name: Carilion Clinic class: OTHER name: Virginia Polytechnic Institute and State University briefSummary: The purpose of this study is to get feedback on a new standardized Measurement-Based Care (MBC) provider training program. conditions: Healthy studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Clinicians completed pre- and post-training surveys. Patient satisfaction was assessed prior to and after clinician training. primaryPurpose: OTHER masking: NONE count: 56 type: ACTUAL name: Training measure: Digital MBC training rate measure: Assessing feasibility of a novel digital MBC training in mental health providers (FIM) measure: Assessing acceptability of a novel digital MBC training program in mental health providers (AIM) measure: Assessing appropriateness of a novel digital MBC training program in mental health providers (IAM) measure: Monitoring and Feedback Attitudes Scale (MFA) measure: Attitudes Towards Standardized Assessment Scales: Monitoring and Feedback (ASA-MF) measure: Clinician Attitude and Satisfaction Survey (CASS) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Carilion Clinic city: Roanoke state: Virginia zip: 24014 country: United States lat: 37.27097 lon: -79.94143 hasResults: False
nctId: NCT06386900 id: S67595 briefTitle: The Impact of Grand Tour Cycling on Sleep and the Hematological and Metabolomic Profile in World-class Cyclists overallStatus: ENROLLING_BY_INVITATION date: 2023-07-01 date: 2024-09-15 date: 2024-12-01 date: 2024-04-26 date: 2024-04-26 name: KU Leuven class: OTHER briefSummary: This project aims to identify the effect of a 3-week Grand Tour (e.g. Tour de France, Giro d'Italia, and Vuelta a España) on sleep, hematological parameters and the serum metabolome in world-class cyclists. conditions: Overreaching studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 16 type: ESTIMATED name: Cyclist measure: Serum metabolome abundance of cyclists participating in a Grand Tour measure: Sleep efficiency during the Grand Tour measure: Total sleep time during the Grand Tour measure: Blood haemoglobin concentration measure: Wakefulness after sleep onset measure: Light sleep measure: Deep sleep measure: REM sleep measure: Red blood cell concentration measure: Subjective fatigue sex: MALE minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: KU Leuven city: Leuven state: Vlaams-Brabant zip: 3000 country: Belgium lat: 50.87959 lon: 4.70093 hasResults: False
nctId: NCT06386887 id: CASE1824 briefTitle: Fasting During Neoadjuvant Chemotherapy in Patient With Epithelial Ovarian Cancer overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2025-12-01 date: 2026-01-01 date: 2024-04-26 date: 2024-04-26 name: Case Comprehensive Cancer Center class: OTHER briefSummary: The goal of this clinical trial is to see if timed fasting (periods of time that you don't eat) in participants who are receiving chemotherapy prior to surgery is achievable, safe and can improve quality of life, symptoms and outcomes (results) compared to participants who receive standard dietary recommendations in individuals being treated for epithelial ovarian cancer . The main questions it aims to answer are:
nctId: NCT06386861 id: 24.210.01e briefTitle: Validating the Spanish "Attitudes Toward Genomics and Precision Medicine" (AGPM). overallStatus: RECRUITING date: 2024-04-14 date: 2024-05-31 date: 2024-12-31 date: 2024-04-26 date: 2024-04-26 name: Boston College class: OTHER briefSummary: the investigators aim to evaluate English and Spanish versions of the "Attitudes toward genomics and precision medicine" instrument (AGPM). This study will help validating a Spanish version of the AGPM among people identifying as Hispanic, Latino/a, or Latinx. Having a valid instrument is important for developing tailored interventions to decrease disparities in genomic healthcare for this population. conditions: Adult ALL studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: 500 English-speaking Latinx individuals 500 Spanish-speaking Latinx individuals primaryPurpose: OTHER masking: NONE count: 1000 type: ESTIMATED name: Attitudes Toward Genomics and Precision Medicine (English) name: Attitudes Toward Genomics and Precision Medicine (Spanish) measure: Psychometric properties measure: Health literacy/numeracy sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Boston College status: RECRUITING city: Chestnut Hill state: Massachusetts zip: 02467 country: United States name: Andrew A Dwyer, FNP-BC, PhD role: CONTACT phone: 617-552-1711 email: andrew.dwyer@bc.edu name: Maria Pineros-Leano, PhD role: SUB_INVESTIGATOR lat: 42.33065 lon: -71.16616 hasResults: False
nctId: NCT06386848 id: 2023PI187 briefTitle: Strategy to Adapt Botulinum Toxin Doses in Dystonia overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-05-01 date: 2024-06-01 date: 2024-04-26 date: 2024-04-26 name: Central Hospital, Nancy, France class: OTHER briefSummary: The study is designed to observ and collect the doses of botulinum toxin injected in dystonia in different centres to compare the initial dose and the dose recommended.
The hypothesis is that we inject smaller doses than we could regarding the recommandations conditions: Dystonia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 100 type: ESTIMATED name: Botulinum toxin measure: First dose of botulinum toxin injected, U measure: Effective dose of botulinum toxin measure: Side effects sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06386835 id: CREC2021.724-T briefTitle: Collagen Paste vs Mucosal Advancement Flap for FIA overallStatus: RECRUITING date: 2024-01-26 date: 2026-03-31 date: 2027-03-31 date: 2024-04-26 date: 2024-04-26 name: Chinese University of Hong Kong class: OTHER briefSummary: The treatment for fistula-in-ano (FIA) remains a challenge to General and Colorectal Surgeons Worldwide. A variety of surgical treatments have been described for high anal fistulas, but none offers the panacea of fistula eradication with guaranteed preservation of continence. This study compares Collagen paste injection to mucosal advancement flap for the treatment of fistula-in-ano. conditions: Fistula-in-ano studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 118 type: ESTIMATED name: Collagen Paste name: Mucosal advancement measure: Clinical healing of Fistula-in-ano measure: 30-day morbidity measure: Quality of life score measure: Postoperative pain score measure: Faecal incontinence rate measure: Hospital readmission rate sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Surgery, Chinese University of Hong Kong status: RECRUITING city: Shatin state: New Territories country: Hong Kong name: Kaori Futaba role: CONTACT email: kfutaba@surgery.cuhk.edu.hk lat: 22.38333 lon: 114.18333 facility: Prince of Wlaes Hospital status: RECRUITING city: Sha Tin country: Hong Kong name: Kaori Futaba role: CONTACT phone: 35051495 email: kfutaba@surgery.cuhk.edu.hk lat: 22.38333 lon: 114.18333 hasResults: False
nctId: NCT06386822 id: 23-1562H briefTitle: The Development of a System for the Measurement of Tremor overallStatus: RECRUITING date: 2023-08-01 date: 2024-12 date: 2024-12 date: 2024-04-26 date: 2024-04-26 name: The Bionics Institute of Australia class: OTHER briefSummary: The goal of this clinical trial is to develop a system which can be used to measure movements in people with Essential Tremor (with or without dystonia). The main questions it aims to answer are:
Participants will don the equipment used to measure their tremor and replicate a series of standardised movements to measure their tremor, in and out of the VR platform. The assessment will take no longer than an hour. conditions: Tremor studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Single group assignment. Up to 90 participants with Essential Tremor and up to 30 Control participants will be recruited to the study. Both groups will undergo the same intervention. primaryPurpose: OTHER masking: NONE count: 120 type: ESTIMATED name: HTC Vive Pro Eye name: HTC Vive Tracker name: Valve Index Controllers name: Biokin measure: To quantify Essential Tremor and dystonia using a measurement system sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Royal Victorian Eye and Ear Hospital status: RECRUITING city: East Melbourne state: Victoria zip: 3002 country: Australia name: Sarah Osborn, BSc role: CONTACT phone: 061396677500 email: sosborn@bionicsinstitute.org lat: -37.81667 lon: 144.9879 hasResults: False
nctId: NCT06386809 id: 2024 -25 briefTitle: Effectiveness of Transcutaneous Auricular Vagus Nerve Stimulation in Bruxism overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-08-01 date: 2024-11-01 date: 2024-04-26 date: 2024-04-26 name: Bandırma Onyedi Eylül University class: OTHER briefSummary: Our study aimed to investigate the effects of transcutaneous auricular vagus nerve stimulation (TAVNS) application on treatment efficacy in bruxism in terms of masseter muscle activity, pain, stress level, sleep and life quality, and autonomic functions. conditions: Bruxism studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 40 type: ESTIMATED name: TAVNS name: Exercise program measure: Pain Severity measure: Oral Health Quality of Life measure: Stress Level measure: Sleep Quality measure: Pressure Pain Threshold measure: Muscle Activation Measurement measure: Measurement of heart rate variability/ Autonomic nervous system evaluation sex: ALL minimumAge: 20 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Bandırma Onyedi Eylül University city: Balıkesir country: Turkey lat: 39.64917 lon: 27.88611 hasResults: False
nctId: NCT06386796 id: Asw.U./867/11/23 briefTitle: Renal Resistive Index as a Predictor of Acute Renal Impairment in High-risk Patients overallStatus: RECRUITING date: 2024-04-01 date: 2025-12-31 date: 2026-04-01 date: 2024-04-26 date: 2024-04-26 name: Aswan University class: OTHER briefSummary: To study the ability of RRI, measured by bedside Doppler ultrasound, in detecting acute kidney injury in high-risk patients admitted to surgical intensive care unit, Aswan university hospital, compared with renal biomarkers and conventional assessment using urine output and serum creatinine levels. conditions: Acute Kidney Injury conditions: Critical Illness studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED measure: Early detection of acute kidney injury. measure: Diagnosis of acute kidney injury. measure: To grade the severity of AKI. measure: To predict clinical outcome (clinical improvement) measure: To predict clinical outcome (necessity for renal replacement therapy) measure: To predict clinical outcome (death) sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Aswan University status: RECRUITING city: Aswan zip: 81528 country: Egypt name: Soudy S Hammad role: CONTACT phone: +201014761523 email: soudi.salah@aswu.edu.eg name: Tarek S Hemaida role: CONTACT phone: 01007363190 email: dr.tarek@aswu.edu.eg name: mohamed H Abolwafa, MSc role: PRINCIPAL_INVESTIGATOR lat: 24.09082 lon: 32.89942 hasResults: False