hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06286943 id: S68124 briefTitle: The Effects of Short-Chain Fatty Acids in Psychosocial Stress-Induced Impairment on Core Executive Functions acronym: GUTSIE overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-03 date: 2025-05 date: 2024-02-29 date: 2024-02-29 name: Universitaire Ziekenhuizen KU Leuven class: OTHER name: United States Department of Defense briefSummary: The aim of the present trial is to examine core executive functions (EFs) as a functional outcome of attenuating the cortisol response to acute laboratory stress through colonic delivery of an Short Chain Fatty Acids (SCFAs) mix (acetate, propionate, butyrate).
Each participant will undergo 2 study visits: one will involve a stress condition and the other will involve a no-stress condition. Each study visit is preceded by a 1-week intervention or placebo period and separated by a 3-4 week washout period. To induce stress, participants will perform the Maastricht Acute Stress Task (MAST) or sham MAST as the control condition. To assess EF performance, three cognitive tasks will be performed 15 minutes after task offset: n-back task for WM; Stop Signal Task for RI; and Wisconsin Card Sorting Test for CF. Saliva samples will be collected before, during and after the (sham) MAST to assess the cortisol response. Blood samples will be collected throughout all study visits to quantify serum SCFAs, inflammatory markers and ACTH. Additionally, cardiovascular variables will be measured, and self-report questionnaires will be completed to evaluate autonomic response to the condition and subjective stress responses, respectively conditions: Executive Function studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 80 type: ESTIMATED name: Short Chain Fatty Acids (SCFAs). name: Placebo name: Maastricht Acute Stress Task name: No-stress control task measure: Working memory measure: Cognitive Flexibility measure: Response Inhibition sex: MALE minimumAge: 20 Years maximumAge: 40 Years stdAges: ADULT hasResults: False
nctId: NCT06286930 id: STU-2023-0470 briefTitle: Cerebellar tDCS Stimulation in Children and Adult Women With Anorexia Nervosa Disorder overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-01-02 date: 2026-01-02 date: 2024-02-29 date: 2024-02-29 name: University of Texas Southwestern Medical Center class: OTHER briefSummary: Hypothesis: Will the use of tDCS brain modulation in the cerebellum assist in restricted behaviors, social cognition and cognitive flexibility in women with anorexia nervosa in addition to other therapies?
1.To observe the impacts and outcome of cerebellar transcranial direct current stimulation (tDCS) measuring the differences between anodal and cathodal stimulation. To observe potential increases in responses to social stimuli, decreases in eating disorder/depressive symptomology via cathodal stimulation. To also observe potential little to no changes in social stimuli and eating disorder/depressive symptomology via anodal stimulation. conditions: Anorexia Nervosa studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 15 type: ESTIMATED name: anodal trans cranial direct current stimulation (tDCS) name: cathodal trans cranial direct current stimulation (tDCS) measure: tDCS impact on social behaviors using Cyberball measure: tDCS impact on social behaviors using the Trust Game measure: neurological impacts of tDCS as measured by fMRI imaging measure: measure the differences of social stimuli and eating disorder/depressive symptomology measure: measure the differences of social stimuli and eating disorder/depressive symptomology measure: measuring the differences of social stimuli and eating disorder/depressive symptomology measuring using the Food Rating Task. measure: measure the differences of social stimuli and mental flexibility with Trail Making Task measure: measure the differences of social stimuli and eating disorder/depressive symptomology utilizing Patient Health Questionnaire-9. sex: FEMALE minimumAge: 15 Years maximumAge: 30 Years stdAges: CHILD stdAges: ADULT hasResults: False
nctId: NCT06286917 id: R24001 briefTitle: Initiation of Noninvasive Ventilation in ALS Patients With Chronic Respiratory Insufficiency acronym: InNIVALS overallStatus: RECRUITING date: 2024-03-05 date: 2028-12 date: 2029-12 date: 2024-02-29 date: 2024-03-22 name: Tampere University class: OTHER briefSummary: This research will study whether noninvasive ventilation (NIV) used to treat chronic respiratory insufficiency in patients with amyotrophic lateral sclerosis (ALS) can be initiated as successfully in the outpatient setting as in the conventional inpatient setting, and what the costs of these alternative initiation methods are. conditions: Ventilation Therapy conditions: ALS conditions: Chronic Respiratory Failure studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: SINGLE whoMasked: INVESTIGATOR count: 120 type: ESTIMATED name: NIV initiation in patients with ALS measure: NIV usage hours according to different initiation locations in patients with ALS measure: Compliance with NIV according to NIV initiation setting in patients with ALS measure: Decrease in blood carbon dioxide levels in patients with ALS depending on the place of NIV initiation. measure: Costs of initiation of NIV in outpatient setting compared with inpatient setting in patients with ALS sex: ALL minimumAge: 18 Years maximumAge: 99 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Tampere University Hospital status: RECRUITING city: Tampere zip: 33520 country: Finland name: Heidi A Rantala, MD, PhD role: CONTACT phone: +3583311611 email: heidi.rantala@tuni.fi name: Lauri Lehtimäki, MD, PhD role: CONTACT phone: +3583311611 email: lauri.lehtimaki@tuni.fi name: Hanna Korkeamäki, MD, MSc role: PRINCIPAL_INVESTIGATOR name: Hannele Hasala, MD, PhD role: SUB_INVESTIGATOR name: Sirpa Leivo-Korpela, MD, PhD role: SUB_INVESTIGATOR lat: 61.49911 lon: 23.78712 hasResults: False
nctId: NCT06286904 id: McMaster-Myant 16633 briefTitle: Sleep Position Pattern Recording overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-12-01 date: 2025-03-30 date: 2024-02-29 date: 2024-03-01 name: Myant Medical Corp. class: INDUSTRY name: McMaster University briefSummary: The main goal of this study is to validate the accuracy of the body position detection by non-invasive wearable monitors (Skiin garments, Myant Medical Corp) during sleep in pregnant participants. This is a first step towards examining the association between maternal sleep position and fetal growth. conditions: Pregnant Women studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 52 type: ESTIMATED name: Skiin Garment system measure: Accuracy of Skiin Garment system for detecting sleep position of pregnant women measure: Questionnaire on wearable device invasiveness and satisfaction measure: Participant recruitment rate measure: Participant retention rate sex: FEMALE stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: McMaster University city: Hamilton state: Ontario zip: L8S 4K1 country: Canada name: Kyle McGowan role: CONTACT phone: 905.521.2100 phoneExt: 21334 email: mcgowank@mcmaster.ca name: Eran Ashwal role: PRINCIPAL_INVESTIGATOR lat: 43.25011 lon: -79.84963 hasResults: False
nctId: NCT06286891 id: CAAE: 73520523.7.0000.0068 briefTitle: Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients overallStatus: RECRUITING date: 2024-02-29 date: 2024-11-01 date: 2025-09-30 date: 2024-02-29 date: 2024-03-19 name: University of Sao Paulo General Hospital class: OTHER briefSummary: The goal of this observational and prospective study is to investigate changes in physical performance, lung function, respiratory and peripheral muscle strength in patients during the postoperative period following pulmonary endarterectomy (PET). conditions: Chronic Thromboembolic Pulmonary Hypertension conditions: Physical Disability conditions: Fragility studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 50 type: ESTIMATED measure: To investigate changes in physical performance measured by Six-Minute Walk Test. measure: To investigate changes in physical performance measured by Short Physical Performance Battery (SPPB). measure: To investigate changes in physical performance by 1-minute sit-to-stand test (1-MSTST). measure: To investigate changes in peripheral muscle strength. measure: To investigate changes in respiratory muscle strength: measure: To investigate changes in lung function test measure by spirometry: measure: To investigate frailty by Clinical Frailty Scale (CFS) measure: To explore potential preoperative and immediate postoperative risk factors as predictors of functional loss. measure: To investigate changes in hemodynamic and respiratory variables during the funcional tests. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Instituto do Coração - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo status: RECRUITING city: São Paulo state: SP zip: 05403-000 country: Brazil name: Orival Freitas Filho, MD role: SUB_INVESTIGATOR name: Fabio B Jatene, MD,PhD role: SUB_INVESTIGATOR name: Kelly CO Abud, PT, PhD role: SUB_INVESTIGATOR lat: -23.5475 lon: -46.63611 hasResults: False
nctId: NCT06286865 id: 260972(REK) briefTitle: Improving Quality of ICD-10 Coding Using AI: Protocol for a Crossover Randomized Controlled Trial acronym: ClinCode overallStatus: RECRUITING date: 2023-10-20 date: 2024-04 date: 2024-04 date: 2024-02-29 date: 2024-02-29 name: University Hospital of North Norway class: OTHER name: The Research Council of Norway briefSummary: The goal of this randomised trial is to learn about the role of AI in clinical coding practice. The main question it aims to answer is:
Can the AI-based CAC system reduce the burden of clinical coding and also improve the quality of such coding? Participants will be asked to code clinical texts both while they use our CAC system and while they do not. conditions: Gastrointestinal Diseases studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: DIAGNOSTIC masking: SINGLE whoMasked: PARTICIPANT count: 30 type: ESTIMATED name: Easy-ICD measure: Time measure: Accuracy sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Norwegian Centre for E-health Research status: RECRUITING city: Tromso state: Troms zip: 9019 country: Norway name: Taridzo F Chomutare, PhD role: CONTACT phone: +4747680032 email: taridzo.chomutare@ehealthresearch.no name: Hercules Dalianis, PhD role: CONTACT phone: +46705681359 email: hercules@dsv.su.se lat: 69.6489 lon: 18.95508 hasResults: False
nctId: NCT06286852 id: EDE BA briefTitle: Italian Language Validation of The Eating Disorder Examination (EDE) - Child Version overallStatus: ACTIVE_NOT_RECRUITING date: 2022-11-01 date: 2023-12-30 date: 2024-06-30 date: 2024-02-29 date: 2024-02-29 name: Meyer Children's Hospital IRCCS class: OTHER briefSummary: Although eating disorders often occur during or after puberty, it is likely that critical antecedent conditions can be established before adolescence. The Eating Disorder Examination has been adapted for children and is described by Bryant - Waugh, Cooper, Taylor and Lask (1996). The EDE is considered the gold standard of measures of eating disorder psychopathology (Wilson, 1993), and this adaptation, which allows its use with a younger age group, is a potentially important addition to the assessment of eating disorders in children. The latest version of EDE, the l7th edition, has now surpassed its predecessors.
The aim of the study is to evaluate the psychometric properties of the Child vers ion EDE (chEDE) translated into Italian, in a sample of patients with eating disorder conditions: Feeding and Eating Disorders of Childhood studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 250 type: ESTIMATED name: Administration of K-SADS-PL- Kiddie-Schedule for Affective Disorder and Schizophrenia-Present and Lifetime version (Kaufmann, 2002) name: Administration of ChEDE- Child Version of the EatingDisorder Examination measure: K-SADS-PL (Kiddie-Schedule for Affective Disorder and Schizophrenia-Present and Lifetime version) questionnaire measure: ChEDE (Child Version of the EatingDisorder Examination) sex: ALL minimumAge: 8 Years maximumAge: 17 Years stdAges: CHILD facility: Meyer Children's Hospital IRCCS city: Firenze country: Italy lat: 43.77925 lon: 11.24626 facility: USL Toscana Centro city: Firenze country: Italy lat: 43.77925 lon: 11.24626 facility: Ospedale Villa Garda city: Garda country: Italy lat: 45.57889 lon: 10.71763 hasResults: False
nctId: NCT06286839 id: AFCRO-150 briefTitle: Study of Cannabidiol (CBD) in Healthy Volunteers overallStatus: COMPLETED date: 2022-05-12 date: 2022-10-28 date: 2022-12-14 date: 2024-02-29 date: 2024-02-29 name: NextEvo Inc. class: INDUSTRY name: Atlantia Food Clinical Trials briefSummary: This was a prospective, single-centre, open label, randomized, two-arm, parallel design study to evaluate the effect of four-weeks consumption of active study product on primary endpoint in healthy adults conditions: Immune System and Related Disorders conditions: Immune System Diseases studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 26 type: ACTUAL name: Cannabidiol (CBD) measure: Plasma CBD pharmacokinetics of twice daily intake of 2 different doses of CBD over three days measure: Evaluate the safety of twice daily intake of 2 different doses of CBD over three 3 days measure: Plasma CBD maximal concentration (Cmax, ng/ml) measure: Plasma CBD time to peak (Tmax, minutes) measure: Percentage Change between groups on whole blood LPS stimulated cytokines (% change) sex: ALL minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Altantia Clinical Trials city: Chicago state: Illinois zip: 60611 country: United States lat: 41.85003 lon: -87.65005 hasResults: False
nctId: NCT06286826 id: ATRESO briefTitle: A Study of Patients Undergoing Surgical Treatment for Oesophageal Atresia overallStatus: RECRUITING date: 2023-10-12 date: 2024-10-12 date: 2026-01-12 date: 2024-02-29 date: 2024-03-04 name: Meyer Children's Hospital IRCCS class: OTHER briefSummary: Oesophageal atresia (EA) is a rare congenital anomaly whose prevalence varies between 1 and 2 per 5000 live births in Europe. This condition is characterised by an interruption of the oesophagus often associated with the presence of a tracheo-oesophageal fistula (FTE).
The primary objective is to assess the incidence of musculoskeletal abnormalities, of any type, in the long term (4 years after surgery) in patients with oesophageal atresia treated surgically by two different approaches: postero-lateral thoracotomy and mini-thoracotomy with muscle preservation conditions: Atresia Esophagus studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 50 type: ESTIMATED name: Postero-lateral thoracotomy name: Minithoracotomy measure: incidence of musculoskeletal abnormalities patients with oesophageal atresia treated surgically measure: incidence of musculoskeletal abnormalities in the short term measure: incidence of musculoskeletal abnormalities in the medium term measure: Evaluation of severity of outcomes in the medium, short and long term measure: Predective Facotrs evaluation sex: ALL minimumAge: 1 Day maximumAge: 13 Years stdAges: CHILD facility: Spedali Civili di Brescia status: RECRUITING city: Brescia zip: 25123 country: Italy name: Daniele Alberti role: CONTACT email: daniele.alberti@unibs.it lat: 45.53558 lon: 10.21472 facility: Meyer Children's Hospital IRCCS status: RECRUITING city: Florence zip: 50139 country: Italy name: Elisa Severi role: CONTACT phone: 0555662900 email: elisa.severi@meyer.it lat: 43.77925 lon: 11.24626 facility: Ospedale Bambino Gesù di Roma status: RECRUITING city: Roma zip: 00165 country: Italy name: Andrea Conforti, MD role: CONTACT email: andrea.conforti@opbg.net lat: 41.89193 lon: 12.51133 hasResults: False
nctId: NCT06286813 id: Akarakoc briefTitle: The Effect of Almond and Extra Virgin Olive Oils on Maintaining Skin Integrity in Neonates overallStatus: RECRUITING date: 2024-03-02 date: 2024-05-03 date: 2024-05-30 date: 2024-02-29 date: 2024-02-29 name: Marmara University class: OTHER briefSummary: This study aimed to evaluate the effects of extra virgin olive and almond oils on maintaining skin integrity in neonates admitted to the neonatal intensive care unit.
Interventional research with two parallel groups and no control group conditions: Skin Care studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Interventional research with two parallel groups (almond olive group and virgin olive oil group) and no control group. primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 120 type: ESTIMATED name: Plant (natural) oils measure: Neonatal skin condition score measure: Skin moisture meter(DMM): sex: ALL minimumAge: 1 Hour maximumAge: 72 Hours stdAges: CHILD facility: Bakırköy Dr. Sadi Konuk Training and Research Hospital status: RECRUITING city: Istanbul zip: 34854 country: Turkey name: AYŞE KARAKOÇ role: CONTACT phone: +905335695138 email: akarakoc@marmara.edu.tr name: Irem Zulal Topçuoglu Arslan role: SUB_INVESTIGATOR lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06286800 id: PRO00036824 briefTitle: Personalized Transcranial Direct Current Stimulation in Stroke Recovery overallStatus: NOT_YET_RECRUITING date: 2024-03-14 date: 2026-03-14 date: 2026-09-14 date: 2024-02-29 date: 2024-02-29 name: The Methodist Hospital Research Institute class: OTHER briefSummary: The central objective of this application is to explore the neural substrate of personalized tDCS (ptDCS) and to determine whether the paradigm for each stroke patient can predict the amount of sustained clinical improvement through increased connectivity as measured by a biomarker of plasticity. conditions: Stroke studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 80 type: ESTIMATED name: Transcranial direct current stimulation (tDCS) with OT name: Sham tDCS with OT measure: fMRI functional connectivity biomarker measure: Wolf Motor Function Test measure: Fugl-Meyer assessment sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06286787 id: HSEARS20221110002 briefTitle: Efficacy of Mountain Craft Training at Enhancing the Resilience and Physio-psychological Well-being of Children From Low-income Families overallStatus: RECRUITING date: 2023-11-16 date: 2024-11-01 date: 2024-11-01 date: 2024-02-29 date: 2024-02-29 name: The Hong Kong Polytechnic University class: OTHER briefSummary: It is imperative to offer adequate community resources and psychosocial support, with a particular focus on enhancing resilience for children from low-income families. This study aims to determine the feasibility, acceptability, and preliminary efficacy of mountain craft training in enhancing resilience and self-esteem, reducing depressive symptoms, and improving the physical health of children from low-income families. conditions: Resilience conditions: Well-being conditions: Children studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 40 type: ESTIMATED name: Intervention name: Placebo measure: Resilience Scale-14 (RS-14) measure: Chinese version of the Center for Epidemiologic Studies Depression Scale for Children (CES-DC) measure: Chinese version of Rosenberg's Self-Esteem Scale (RSES) measure: The children's peak expiratory flow rate sex: ALL minimumAge: 12 Years maximumAge: 14 Years stdAges: CHILD facility: The Asbury Methodist Social Service status: RECRUITING city: Hong Kong country: China name: Chung role: CONTACT email: okjoyce.chung@polyu.edu.hk lat: 22.39407 lon: 114.13737 hasResults: False
nctId: NCT06286774 id: 2096884 briefTitle: Sleep as a Mechanism of Change in Alcohol Use acronym: ReTRAIN overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2028-04-01 date: 2028-04-01 date: 2024-02-29 date: 2024-02-29 name: University of Missouri-Columbia class: OTHER briefSummary: This project aims to evaluate improvement of insomnia as a mechanism of improvement in alcohol use outcomes. conditions: Insomnia conditions: Alcohol; Harmful Use studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Subjects will be randomized to Cognitive Behavioral Therapy for Insomnia (CBT-I) or waitlist control. primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: PI Miller and study therapists will be blinded to assessment outcomes, and assessment RAs will be blinded to participant condition. whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 256 type: ESTIMATED name: Cognitive Behavioral Therapy for Insomnia measure: Insomnia Symptoms measure: Drinking quantity measure: Alcohol-related consequences measure: Treatment willingness (alcohol) measure: Alcohol craving measure: Negative emotionality measure: Response inhibition measure: Working memory measure: Delay discounting measure: Alcohol to help with sleep measure: Heartrate variability measure: Dysfunctional Beliefs and Attitudes about Sleep Scale sex: ALL minimumAge: 18 Years maximumAge: 49 Years stdAges: ADULT facility: University of Missouri-Columbia city: Columbia state: Missouri zip: 65212 country: United States lat: 38.95171 lon: -92.33407 hasResults: False
nctId: NCT06286761 id: 2100332 briefTitle: Routine Validation and Reproducibility Testing of Laboratory Measures and Research Techniques Used for Metabolism Research (VAL) acronym: VAL overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2028-03 date: 2028-03 date: 2024-02-29 date: 2024-02-29 name: Bettina Mittendorfer class: OTHER briefSummary: The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research on chronic diseases (obesity, pre-diabetes and type-2 diabetes, dyslipidemia, non-alcoholic fatty liver disease, cardiovascular disease, etc.), nutrition, and metabolism (the process by which a substance is handled in your body) at the University of Missouri. As technology changes and we start to use new testing methods, it is necessary to compare results from old tests, equipment and devices and new tests, equipment, or devices and the reproducibility of these measurements to make sure we are getting accurate results. Reproducibility means performing the same test more than once to see if the same results can be achieved each time. conditions: Obesity studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED name: endothelial cell collection measure: Validation and reproducibility testing for blood assays measure: Validation and reproducibility testing for endothelial cell collection measure: Validation and reproducibility testing for mixed meal ingestion measure: Validation and reproducibility testing for glucose tolerance testing measure: Validation and reproducibility testing for DEXA measure: Validation and reproducibility testing for MRI measure: Validation and reproducibility testing for MRS sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False