hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06383260 id: 009-0001-7719-1189 briefTitle: Assessing the Prevalence of Attention Deficit Hyperactivity Disorder (ADHD) Symptoms in Undiagnosed Young Adults:A Cross Sectional Study overallStatus: COMPLETED date: 2023-07-01 date: 2023-09-01 date: 2023-09-01 date: 2024-04-25 date: 2024-04-25 name: Jinnah Sindh Medical University class: OTHER briefSummary: To asses the prevalence of Attention deficit hyperactivity disrorder in undiagnosed young adults. conditions: Finding the Prevalence of ADHD in Undiagnosed Young Adults studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 200 type: ACTUAL name: Behavioral diagnostic measure: Assess the prevalence of undiagnosed ADHD in Young adults sex: ALL minimumAge: 18 Years maximumAge: 24 Years stdAges: ADULT facility: JSMU city: Karachi state: Sindh zip: 75330 country: Pakistan lat: 24.8608 lon: 67.0104 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2023-09-01 uploadDate: 2024-04-21T04:06 filename: Prot_SAP_000.pdf size: 834129 hasResults: False
nctId: NCT06383247 id: AMU-PD-multicenter briefTitle: The Efficacy of Repetitive Transcranial Magnetic Stimulation With Precision Neuronavigation in Parkinson's Disease overallStatus: NOT_YET_RECRUITING date: 2024-11-01 date: 2028-12-31 date: 2030-12-31 date: 2024-04-25 date: 2024-04-29 name: Anhui Medical University class: OTHER briefSummary: Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive and widely used neuromodulation technology. Small sample studies have shown that rTMS treatment can significantly improve the symptoms of Parkinson's disease(PD) and delay the progression of the disease. In order to further explore the effectiveness of rTMS in the treatment of PD and lay the foundation for its clinical promotion, our research team plans to conduct a randomized double-blind controlled study of rTMS in the treatment of PD in multiple centers across the country. conditions: Parkinson Disease conditions: Transcranial Magenetic Stimualtion conditions: Supplementary Motor Area studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 312 type: ESTIMATED name: transcranial magnetic stimulation measure: Movement Disorder Society- Unified Parkinson's Disease Rating Scale III scores measure: Movement Disorder Society- Unified Parkinson's Disease Rating Scale Ⅰ scores measure: Movement Disorder Society- Unified Parkinson's Disease Rating Scale Ⅱ scores measure: Movement Disorder Society- Unified Parkinson's Disease Rating Scale Ⅳ scores sex: ALL minimumAge: 40 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Cognitive Neuropsychology Lab Anhui Medical University city: Hefei state: Anhui zip: 230032 country: China lat: 31.86389 lon: 117.28083 hasResults: False
nctId: NCT06383234 id: PAR 89/21 briefTitle: REduced Pain After Bariatric Surgery - Sleeve Gastrectomy acronym: REPABS-SG overallStatus: COMPLETED date: 2022-01-10 date: 2023-09-21 date: 2023-09-28 date: 2024-04-25 date: 2024-04-25 name: Fondazione Policlinico Universitario Campus Bio-Medico class: OTHER briefSummary: This study aims to analyze the effect of laparoscopic guided transversus abdominis plane (LG-TAP) block compared to placebo for postoperative analgesia following laparoscopic sleeve gastrectomy. One group of participants received a (LG-TAP) block with local anesthetic while the other group received (LG-TAP) block with saline solution (placebo). conditions: Pain conditions: Postoperative Pain conditions: Acute Pain conditions: Analgesia conditions: Bariatric Surgery Candidate conditions: Anesthesia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 110 type: ACTUAL name: LG-TAP block with local anesthetic name: LG-TAP block with saline solution name: Port site infiltration measure: Pain Score measure: Morphine Consumption measure: Toradol Consumption measure: Nausea and/or vomiting measure: Lenght of Hospital Stay measure: Time to walking measure: Time to first flatus measure: Surgical Complication sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fondazione Policlinico Universitario Campus Bio-medico city: Rome zip: 00128 country: Italy lat: 41.89193 lon: 12.51133 hasResults: False
nctId: NCT06383221 id: 83244570 briefTitle: Study of the Intervention Effect of Stepped-care Models on Depression Symptoms During Pregnancy. overallStatus: NOT_YET_RECRUITING date: 2024-05-20 date: 2025-10-20 date: 2026-03-10 date: 2024-04-25 date: 2024-04-25 name: Fangbiao Tao class: OTHER briefSummary: In this study, pregnant women were screened and managed for depression in three time windows: early pregnancy, mid-pregnancy, and late pregnancy. Pregnant women who screened positive for depression during pregnancy were dynamically enrolled in the study and stratified into randomized groups based on gestation period (early/mid/late) and randomly assigned to the intervention and control groups on a 1:1 basis. Pregnant women in the intervention group attended a three-week "mental fitness boot camp" and were assessed at 3 weeks, and if they still screened positive for depression, they were offered 4 times one-on-one counseling sessions by the obstetrician. The control group received routine care. conditions: Perinatal Depression conditions: Stepped Care studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 600 type: ESTIMATED name: "Mental Fitness Boot Camp - Advanced Counseling" Step-by-Step Care measure: Edinburgh Postnatal Depression Scale measure: Generalized Anxiety Disorder measure: World Health Organization Five-item Well-Being Index sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06383208 id: 2024-ZF-13 briefTitle: Cardiovascular-Renal Adverse Prognosis Assessment System for Coronary Heart Disease With Chronic Kidney Disease Based on Metabolomics acronym: CRUISE-MET overallStatus: RECRUITING date: 2024-04-01 date: 2027-03-31 date: 2027-03-31 date: 2024-04-25 date: 2024-04-25 name: China-Japan Friendship Hospital class: OTHER briefSummary: Coronary heart disease (CHD) combined with chronic kidney disease (CKD) affects a substantial portion of the population and carries a significant disease burden, often leading to poor outcomes. Despite efforts to strictly control traditional risk factors, the efficacy in improving outcomes for patients with both CHD and CKD has been limited. Recent advancements in lipid metabolism research have identified new lipid metabolites associated with the occurrence and prognosis of CHD and CKD. Our preliminary trial has shown that levels of certain lipid metabolites, such as Cer(18:1/16:0), HexCer(18:1/16:0), and PI(18:0/18:1), are notably elevated in patients with CHD and reduced kidney function compared to those with relatively normal kidney function. This suggests that dysregulation of these non-traditional lipid metabolites may contribute to residual risk for adverse outcomes in these patients.
Furthermore, the emerging concept of "cardiovascular-kidney-metabolic syndrome" and the availability of new treatment options highlight the urgent need for a risk stratification tool tailored to modern management strategies and treatment goals to guide preventive measures effectively. To address this, we propose to conduct a prospective cohort study focusing on CHD combined with CKD. This study aims to comprehensively understand the clinical characteristics, diagnosis, treatment status, and cardiovascular-kidney prognosis in these patients. Through advanced metabolomics analysis, we seek to identify lipid metabolism profiles and non-traditional lipid metabolites associated with the progression of coronary artery disease in CHD-CKD patients. Leveraging clinical databases and metabolomics data, we will develop a robust risk prediction model for adverse cardiovascular-kidney outcomes, providing valuable guidance for clinical diagnosis, treatment decisions, and ultimately improving patient prognosis. conditions: Chronic Kidney Diseases conditions: Coronary Heart Disease conditions: Lipid Metabolism Disorders studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 470 type: ESTIMATED name: lipid metabolomics measure: Incidence of cardiovascular adverse events measure: Incidence of Renal composite endpoint event measure: Incidence of All-cause mortality measure: Incidence of Repeat revascularization measure: Incidence of bleeding sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: China-Japan Friendship Hospital status: RECRUITING city: Beijing state: Beijing country: China name: Chen Qiang, MD role: CONTACT phone: +86 13882712184 email: dawangchen@163.com lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06383195 id: SBA 24/189 briefTitle: The Reliability and Validity of the Ankylosing Spondylitis Performance Index (ASPI) in Enthesitis-Related Arthritis overallStatus: RECRUITING date: 2024-03-21 date: 2026-03-20 date: 2026-03-20 date: 2024-04-25 date: 2024-04-25 name: Hacettepe University class: OTHER briefSummary: This study assesses the test-retest reliability, construct validity, and minimal detectable change of the Ankylosing Spondylitis Performance Index (ASPI) in assessing the physical function of patients with Enthesitis-related arthritis (ERA). conditions: Enthesitis Related Arthritis conditions: Enthesitis Related Arthritis, Juvenile studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 40 type: ESTIMATED measure: Ankylosing Spondylitis Performance Index (ASPI) measure: Childhood Health Assessment Questionnaire (CHAQ) measure: Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) measure: Bath Ankylosing Spondylitis Functional Index (BASFI) measure: Bath Ankylosing Spondylitis Metrology Index (BASMI) measure: Modified Paediatric Mini Mental Scale (MPMMS) sex: ALL minimumAge: 7 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Hacettepe University status: RECRUITING city: Ankara country: Turkey name: Sinan Buran, RA role: CONTACT email: pt.sinanburan@gmail.com lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06383182 id: Y (2024) 054 briefTitle: Change in Serum Biomarkers After Endovascular Treatment for Acute Anterior Circulation Large Vessel Occlusion overallStatus: NOT_YET_RECRUITING date: 2024-05-07 date: 2026-12-30 date: 2026-12-30 date: 2024-04-25 date: 2024-04-25 name: General Hospital of Shenyang Military Region class: OTHER briefSummary: Acute ischaemic stroke (AIS) results in high rates of neurological morbidity and mortality, especially in patients with large vessel occlusion (LVO). Endovascular therapy (EVT) has been approved as the most effective treatment for patients with LVO , but about half patients undergoing EVT did not achieve good outcome. The mechanisms of poor prognosis are complex. How to accurately identify serological biomarkers related to patients' clinical prognosis is an important research topic nowadays. conditions: Ischemic Stroke studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 200 type: ESTIMATED name: endovascular treatment measure: Dynamic changes in serum biomarkers after endovascular treatment measure: favourable functional outcome, defined as modified Rankin Scale (mRS) 0-2 measure: excellent functional outcome, defined as modified Rankin Scale (mRS) 0-1 measure: distribution of modified Rankin Scale (mRS) score measure: early neurological improvement, defined as 4 or more decrease in National Institute of Health stroke scale (NIHSS) measure: changes in National Institute of Health stroke scale (NIHSS) measure: symptomatic intracranial hemorrhage (sICH) measure: occurence of new stroke or other vascular events measure: the association between cerebral circulation time (CCT) and clinical outcomes measure: the association between serum biomarkers and clinical outcomes measure: the association between serum biomarkers and status of vessel recanalization sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: General Hospital of Northern Theater Command city: ShenYang zip: 110840 country: China lat: 41.79222 lon: 123.43278 hasResults: False
nctId: NCT06383169 id: wanglizhong briefTitle: Impact of External Drainage of the Lumbar Cistern in Patients With Hydrocephalus Following Meningioma Surgery and Its Influence on Patient Satisfaction overallStatus: COMPLETED date: 2019-05-01 date: 2022-05-01 date: 2022-05-30 date: 2024-04-25 date: 2024-04-25 name: First Hospital of Zhangjiakou City class: OTHER briefSummary: This study aims to investigate the effect of external lumbar cistern drainage in preventing postoperative hydrocephalus in patients who have undergone meningioma surgery and its impact on patient satisfaction. conditions: Investigate the Effect of External Lumbar Cistern Drainage in Preventing Postoperative Hydrocephalus in Patients Who Have Undergone Meningioma Surgery studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 86 type: ACTUAL measure: Comparison of general clinical data measure: Comparison of the response rate measure: Comparison of GCS scores and intracranial pressure measure: Comparison of KPS scores and satisfaction sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: First Hospital of Zhangjiakou City city: Zhangjiakou country: China lat: 40.81 lon: 114.87944 hasResults: False
nctId: NCT06383156 id: MD157/2023 briefTitle: The Use of Lung US, Fluoroscopy and Auscultation to Confirm Proper Positioning of Left Sided DLT : A Comparative Study overallStatus: NOT_YET_RECRUITING date: 2024-04-17 date: 2024-09-18 date: 2024-10-01 date: 2024-04-25 date: 2024-04-25 name: Ain Shams University class: OTHER briefSummary: The aim of this study is to compare between The Use of Lung ultrasound, Fluoroscopy and Auscultation to Confirm Proper Positioning of Left Sided DLT in elective thoracic surgeries. conditions: Endotracheal Tube Wrongly Placed During Anesthetic Procedure studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 90 type: ESTIMATED name: Double lumen endotracheal tube measure: the specificity in confirming the position of the LDLT and matching the observation of flexible bronchoscope measure: sensitivity and accuracy in confirming the position of the LDLT. sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT hasResults: False
nctId: NCT06383143 id: AC-020-IT briefTitle: Promoting Diagnosis and Management of AL in Italy (ProDigALIty) acronym: ProDigALIty overallStatus: RECRUITING date: 2023-05-01 date: 2025-05-01 date: 2025-05-01 date: 2024-04-25 date: 2024-04-25 name: IRCCS Policlinico S. Matteo class: OTHER briefSummary: We plan to establish a dedicated network of Italian Hematologic Departments interconnected with the Amyloidosis Research and Treatment Center in Pavia to:
3. Investigate the clinical utility of novel diagnostic technologies, including light chain sequencing and N-glycosylation analysis conditions: AL Amyloidosis conditions: Smoldering Multiple Myeloma conditions: Monoclonal Gammopathy of Undetermined Significance studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 760 type: ESTIMATED name: no intervention measure: Assess proportion of patients with newly diagnosed AL identified through the biomarker-based screening of at-risk patient measure: Assess the proportion of patients with deep haematological response after frontline therapy (best response evaluation) in the new enhanced, contemporary, real-world series of AL patients enrolled during the study. measure: 3. Identify associations of clonal light chain features with different clinical features at baseline. measure: Description of the baseline characteristics and 6-months outcome, as well as the time to AL development for patients with AL identified through the biomarker-based screening measure: Description of the baseline characteristics of MGUS/SMM patients with abnormal FLCR measure: Identification of clinical and biological correlates of hematological response measure: To verify whether implementing a dedicated pipeline for referral of AL patients to the National Referral Center will increase the proportion of patients from spoke centers measure: Identification of associations of clonal light chain features with event-free survival measure: Validation of existing algorithms for predicting AL amyloidosis status sex: ALL minimumAge: 18 Years maximumAge: 99 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Azienda Ospedaliera Policlinico Consorziale status: RECRUITING city: Bari country: Italy name: PELLEGRINO MUSTO, MD role: CONTACT phone: 080 5593471 email: ematologiacontrapianto@policlinico.ba.it name: PELLEGRINO MUSTO, MD role: PRINCIPAL_INVESTIGATOR name: Angela Minervini, MD, PhD role: SUB_INVESTIGATOR lat: 41.11148 lon: 16.8554 facility: Azienda Ospedaliero Universitaria Policlinico G.Rodolico - San Marco status: RECRUITING city: Catania country: Italy name: Francesco Di Raimondo, MD role: CONTACT phone: 095/378.1956 email: segremat@unict.it name: Francesco Di Raimondo, MD role: PRINCIPAL_INVESTIGATOR name: Concetta Maria Sebastiana Conticello, MD, PhD role: SUB_INVESTIGATOR lat: 37.49223 lon: 15.07041 facility: Fondazione Irccs Policlinico San Matteo status: RECRUITING city: Pavia country: Italy name: GIOVANNI PALLADINI, MD, PhD role: CONTACT phone: +390382502994 email: segreteria.amiloidosi@smatteo.pv.it name: GIOVANNI PALLADINI, MD, PhD role: PRINCIPAL_INVESTIGATOR name: Luca Arcaini, MD role: PRINCIPAL_INVESTIGATOR name: Mario Ulisse Nuvolone, MD, PhD role: SUB_INVESTIGATOR lat: 45.19205 lon: 9.15917 facility: EMATOLOGIA - Città della Scienza e Salute - Torino status: RECRUITING city: Torino country: Italy name: FRANCESCA MARIA GAY, MD, PhD role: CONTACT phone: 011.633.5550 - 5935 email: ematologia@cittadellasalute.to.it name: FRANCESCA MARIA GAY, MD, PhD role: PRINCIPAL_INVESTIGATOR name: Stefania Oliva, MD, PhD role: SUB_INVESTIGATOR lat: 45.07049 lon: 7.68682 hasResults: False
nctId: NCT06383130 id: 24SM8792 briefTitle: London Asthma Diagnostics Study acronym: LADS overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-12 date: 2026-07 date: 2024-04-25 date: 2024-04-25 name: Imperial College London class: OTHER name: Asthma UK name: General Practitioners Research Institute briefSummary: The goal of this trial is to learn if the addition of oscillometry with reversibility testing increases diagnostic accuracy in adult asthma diagnosis, when added to current standard of care tests: spirometry with reversibility testing and Fractional Exhaled Nitric Oxide (FeNO). The main question it aims to answer is:
* Optionally participate in our qualitative substudy on patients views and attitudes to asthma testing and oscillometry conditions: Asthma studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 225 type: ESTIMATED name: Oscillometry with reversibility testing name: Breath volatile testing name: Nasal eosinophil peroxidase name: Handheld capnometry measure: To evaluate the diagnostic accuracy (sensitivity, specificity) of a combination of oscillometry ± reversibility, spirometry ± reversibility and FeNO measure: To conduct an analysis comparing the diagnostic accuracy of (i) oscillometry ± reversibility with spirometry ± reversibility, (ii) spirometry±reversibility with FeNO and (iii) oscillometry ±reversibility and FeNO measure: To compare the concordance of positive and negative test results for (i) oscillometry±reversibility, (ii) spirometry ±reversibility and (iii) Fractional Exhaled Nitric Oxide (FeNO) measure: To collect data on (i) testing time, (ii) testing burden, (iii) general feasibility of implementation of the asthma diagnostic tests measure: To evaluate the diagnostic accuracy of the targeted reactive aldehyde species (RASP) panel in breath for asthma diagnosis measure: To evaluate the diagnostic accuracy of nasal biomarker eosinophil peroxidase (EPX) measure: To evaluate the diagnostic accuracy of tidal breath CO2 waveforms using the N-Tidal handheld capnometry device sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Imperial College Healthcare NHS Trust city: London zip: W2 1PG country: United Kingdom lat: 51.50853 lon: -0.12574 facility: Imperial College Healthcare NHS Trust city: London zip: W21NY country: United Kingdom name: Eleanor Quek, MBBS role: CONTACT phone: 07411429994 email: e.quek@imperial.ac.uk name: Salman Siddiqui, PhD role: CONTACT email: s.siddiqui@imperial.ac.uk name: Salman Siddiqui, PhD role: PRINCIPAL_INVESTIGATOR lat: 51.50853 lon: -0.12574 facility: Nottingham University Hospitals NHS Trust city: Nottingham zip: NG7 2UH country: United Kingdom name: Matthew Martin, PhD role: CONTACT email: matthew.martin4@nottingham.ac.uk name: Matthew Martin, PhD role: SUB_INVESTIGATOR lat: 52.9536 lon: -1.15047 hasResults: False
nctId: NCT06383117 id: UL1TR002378 type: NIH link: https://reporter.nih.gov/quickSearch/UL1TR002378 id: KL2TR002381 type: NIH link: https://reporter.nih.gov/quickSearch/KL2TR002381 briefTitle: Understanding Effects of Calcium on the Gut-Bone Axis overallStatus: COMPLETED date: 2023-10-17 date: 2024-02-23 date: 2024-02-23 date: 2024-04-25 date: 2024-04-25 name: University of Georgia class: OTHER name: National Center for Advancing Translational Sciences (NCATS) briefSummary: The study team is inviting 13 healthy people to complete a study to explore how calcium affects hormones and bones after eating. Participants will be asked to complete two study visits within eight weeks. Before each visit, participants will be asked to not eat or drink (except water) for 9 hours. At each visit, participants will eat the same meal provided by the research team. Along with their meal, they will take a pill - in one session, this will be a calcium supplement, and in the other, a placebo (a pill with no calcium), but they won't know which one they are taking at which session. A phlebotomist will draw blood before the meal and pill, then again several times after eating. Blood draws will take place over three hours. During that time, participants will complete questionnaires about health, diet, and physical activity.