hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06334679 id: zeynepersoz briefTitle: The Effect of Cold Gel Pack Application on Itching in Burn Patients in the Maturation Stage overallStatus: RECRUITING date: 2024-01-15 date: 2024-11-15 date: 2024-12-15 date: 2024-03-28 date: 2024-03-28 name: Marmara University class: OTHER briefSummary: Burn is a serious trauma that causes acute damage to the skin and subcutaneous tissues due to the effect of heat, electricity, radiation, physical, and chemical substances. It has been reported that the incidence of itching is high in burn patients during the maturation stage of wound healing. The literature suggests that in managing the symptom of itching, skin hydration support along with cold application methods can also be used. The integrity of the skin, the duration, frequency, characteristics, areas of itching, and identifying conditions that increase or decrease itching are important for managing itching. This study is planned to be conducted with a randomized controlled design to examine the effect of applying cold gel packs to burn areas of burn patients during the maturation stage on itching. This researcher's hypothesis is that burn patients who applied cold gel packs to burn areas during the maturation phase had lower itching severity (frequency, duration, intensity) than those who did not. conditions: Burns conditions: Pruritus studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: It is a prospective interventional type two-group randomized controlled clinical study. Distribution according to the groups and layers to be assigned for each intervention; Group-1 (Experiment) was designed as clinical routine (liquid petroleum jelly) and cold gel pack, and Group-2 (Control) was designed as clinical routine (liquid petroleum jelly). primaryPurpose: SUPPORTIVE_CARE masking: SINGLE maskingDescription: When cold application studies in the literature are examined, cold gel packs are placed in a sheath and contacted with the skin of the patients. Therefore, due to the nature of the application method to be used, patients and the researcher will not be considered blind. The evaluator will be considered blind in the analysis of the study. whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Cold Gel Packet Application measure: Itching severity measure: Itching grade sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Kartal Dr.Lütfi Kırdar City Hospital status: RECRUITING city: Istanbul country: Turkey name: Zeynep Ersoz role: CONTACT phone: 05553496718 email: zeynepersoz08@gmail.com name: Gaye Filinte role: CONTACT phone: 5339576333 email: gayetaylan@yahoo.com lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06334666 id: SI 172/2024 briefTitle: The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD. overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-04-01 date: 2026-06-01 date: 2024-03-28 date: 2024-03-28 name: Mahidol University class: OTHER briefSummary: The study conducted a health survey among Thai adults in 2022 and found a significant increase in obesity and nonalcoholic fatty liver disease (NAFLD), leading to metabolic-associated steatotic liver disease (MASLD). The prevalence of NAFLD was 19.7%, with higher rates in individuals with metabolic syndrome and diabetes. MASLD is associated with insulin resistance and genetic polymorphisms, particularly the patatin like phospholipase domain containing 3-rs738409 variant. Additionally, physical activity was inversely related to liver disease risk, with higher step counts associated with reduced incidence of NAFLD and liver-related mortality. The study aims to investigate the impact of dietary advice and pedometer use on physical activity levels and health outcomes in MASLD patients over 24 weeks. conditions: Daily Step Count conditions: MASLD conditions: BMI conditions: Metabolic Syndrome conditions: NAFLD conditions: Insulin Resistance conditions: Genetic Polymorphism conditions: Cardiovascular Disease (CVD) studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 86 type: ESTIMATED name: Encourage using pedometer measure: To compare the changes in hepatic fat accumulation assessed by MRI-PDFF between the MASLD patient group wearing pedometers to promote physical activity, compared to the MASLD patient group with normal daily walking behavior. measure: To compare changes in metabolic parameters between the MASLD patient group wearing pedometers to promote physical activity, compared to the MASLD patient group with normal daily walking behavior, along with dietary adjustments. measure: To study the impact of genes on changes in hepatic fat accumulation between the MASLD patient group wearing pedometers to promote physical activity, compared to the MASLD patient group with normal daily walking behavior. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06334653 id: H-23069670 briefTitle: Exercise-regulated Organ Crosstalk, Influence of IL-6 acronym: EVEX overallStatus: NOT_YET_RECRUITING date: 2024-04-09 date: 2024-11-01 date: 2024-11-01 date: 2024-03-28 date: 2024-04-09 name: Helga Ellingsgaard class: OTHER briefSummary: Overall the study investigates organ crosstalk during exercise. More specifically, the study investigates the role of IL-6 in regulating glucose, fatty acid, and amino acid kinetics at whole body level and in skeletal muscle, liver, and brain. Furthermore, the study investigates the uptake and release of extracellular vesicles in skeletal muscle, liver, and brain in reponse to exercise. conditions: Healthy Volunteers Only conditions: Energy Metabolism studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 30 type: ESTIMATED name: exercise measure: Whole body substrate kinetics. measure: Tissue specific utilization and production of substrates. measure: IL-6 regulation of protein synthesis and degradation. measure: Number of EVs from muscle, liver, and brain. measure: Size of EVs from muscle, liver, and brain. measure: EVs from muscle, liver, and brain. measure: Influence of exercise on EV number. measure: Influence of exercise on EV size measure: Influence of exercise on EV content. measure: Tissue specific proteomic content of EVs. measure: Lactate. measure: Pyruvate. measure: Keto acids. measure: Ketone bodies. measure: Influence of IL-6 on fatty acid oxidation rates. measure: Influence of IL-6 on insulin. measure: Influence of IL-6 on glucagon. measure: Influence of IL-6 on epinephrine. measure: Influence of IL-6 on norepinephrine. measure: IL-6 levels. measure: Influence of IL-6 on substrate usage. measure: Influence of IL-6 on perceived exertion. sex: MALE minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Rigshospitalet city: Copenhagen state: Capital Region zip: 2100 country: Denmark name: Helga Ellingsgaard, PhD role: CONTACT phone: +4535457544 email: helga.ellingsgaard@regionh.dk name: Peter S Plomgaard, MD PhD role: CONTACT phone: +4535457544 email: Peter.Plomgaard@regionh.dk lat: 55.67594 lon: 12.56553 hasResults: False
nctId: NCT06334640 id: 37C302 briefTitle: Sleeping Quality and Chronic Ocular Diseases acronym: SONNO-OCU overallStatus: RECRUITING date: 2023-10-17 date: 2024-10-17 date: 2025-10-17 date: 2024-03-28 date: 2024-03-28 name: Istituto Auxologico Italiano class: OTHER briefSummary: To assess the impact of sleep quality on chronic eyes diseases conditions: Sleep Disorder studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 186 type: ESTIMATED name: Three questionaires measure: Proportion of sleep disorders in patients and healthy volunteers sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Istituto Auxologico Italiano IRCCS status: RECRUITING city: Milan zip: 20145 country: Italy name: Paolo Milani, MD role: CONTACT lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06334627 id: ENREACH briefTitle: Every Newborn-Reach Up Early Education Intervention for All Children- a Parent Group Intervention for School Readiness in Bangladesh, Nepal, and Tanzania acronym: EN-REACH overallStatus: ACTIVE_NOT_RECRUITING date: 2022-05-03 date: 2024-04-15 date: 2024-09-15 date: 2024-03-28 date: 2024-03-28 name: London School of Hygiene and Tropical Medicine class: OTHER name: International Centre for Diarrhoeal Disease Research, Bangladesh name: Golden Community, Nepal name: Muhimbili University of Health and Allied Sciences name: University of Glasgow briefSummary: The goal of this clinical trial is to test the effect of a pre-primary education parent group intervention in children with and without disability in Nepal Bangladesh and Tanzania. The main question it aims to answer are:
Participants will attend parent group sessions every two weeks for a total of 9 sessions. Researchers will compare a control group to see if there are impacts on school readiness and child development. conditions: Child Development conditions: Child Development Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 1651 type: ACTUAL name: Pre-Primary Intervention measure: Measuring Early Learning Quality and Outcomes (MELQO Tool) measure: The Pediatric Evaluation of Disability Inventory measure: Washington Group Questionnaire measure: The Wechsler Preschool & Primary Scale of Intelligence measure: Pre-school Register measure: Mental Health Questionnaire measure: Pediatric Quality of Life Inventory (PEDSQL Tool) sex: ALL minimumAge: 4 Years maximumAge: 6 Years stdAges: CHILD facility: International Centre for Diarrheal Disease Research, Bangladesh city: Dhaka country: Bangladesh lat: 23.7104 lon: 90.40744 facility: Golden Community city: Lalitpur country: Nepal lat: 27.67658 lon: 85.31417 facility: Muhimbili University of Health and Allied Sciences city: Dar Es Salaam country: Tanzania lat: -6.82349 lon: 39.26951 hasResults: False
nctId: NCT06334614 id: IIT_iReach briefTitle: iReach: a Rehabilitative Medical Device overallStatus: NOT_YET_RECRUITING date: 2024-12-08 date: 2025-05-08 date: 2025-12-08 date: 2024-03-28 date: 2024-03-28 name: Istituto Italiano di Tecnologia class: OTHER briefSummary: The broad goal of this clinical trial is to demonstrate whether a one-month rehabilitative training with our medical device, iReach, can promote the recovery of spatial and sensorimotor abilities and the cortical reorganization process in children with visual impairment between 3 and 36 months of age. conditions: Blindness conditions: Visual Impairment studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Participant masking because the clinical trial involves infants whoMasked: PARTICIPANT count: 55 type: ESTIMATED name: iReach measure: Incidence of Device Adverse Events measure: Change in motor skills after training with iReach medical device measure: Perceptual responses to multisensory stimuli measure: Change in motor abilities following the rehabilitation with the iReach medical device measure: Variation in the power of the cortical activity following the rehabilitation with the iReach medical device sex: ALL minimumAge: 3 Months maximumAge: 36 Months stdAges: CHILD hasResults: False
nctId: NCT06334601 id: 09C333 briefTitle: Diurnal Evaluation of OSA Upper Airway Collapsibility and Muscle Responsiveness acronym: Muscle-OSA overallStatus: RECRUITING date: 2023-01-15 date: 2025-12-31 date: 2025-12-31 date: 2024-03-28 date: 2024-03-28 name: Istituto Auxologico Italiano class: OTHER briefSummary: In the framework of pathophysiological trait in obstructive sleep apnea (OSA) patients, a simplified method is proposed to measure upper airway (UA) collapsibility and muscle responsiveness during wakefulness. conditions: Obstructive Sleep Apnea studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 66 type: ESTIMATED name: Tests of upper airway collapsibility and muscle responsiveness. measure: Upper airway collapsibility measure: Upper airway muscle responsiveness sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS Istituto Auxologico Italiano,Ospedale San Luca status: RECRUITING city: Milano zip: 20145 country: Italy name: Elisa Perger, MD role: CONTACT phone: +390261911 phoneExt: 2705 email: e.perger@auxologico.it lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06334588 id: APHP240105 id: 2023-A02668-37 type: REGISTRY domain: ID-RCB briefTitle: Understanding the Mechanisms of Autism : an MRI and Social Cognition Study acronym: ECLAT overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2029-04 date: 2031-04 date: 2024-03-28 date: 2024-03-28 name: Assistance Publique - Hôpitaux de Paris class: OTHER briefSummary: The main goal of this study is to investigate anatomo-functional brain abnormalities associated with autism spectrum disorders using a multimodal brain imaging approach, as well as its links to social cognition difficulties measured using eye-tracking conditions: Autism Spectrum Disorder studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: DIAGNOSTIC masking: NONE count: 160 type: ESTIMATED name: MRI name: Eye-tracking name: Clinical Scales name: Research of genetic anomalies measure: Rest cerebral blood flow (CBF) measure: Measurements of white matter microstructure - fractional anisotropy measure: Measurements of white matter microstructure - mean diffusivity measure: Measurements of white matter microstructure - radial diffusivity measure: Measurements of white matter microstructure - axial diffusivity measure: Measurements of resting state functional connectivity measure: Correlation between social perception and multimodal brain imaging measure: Correlation between clinical severity and multimodal brain imaging measure: Imaging abnormalities associated with known genetic mutations measure: Social perception abnormalities associated with known genetic mutations measure: Anatomic changes over time - study of developmental trajectory measure: Social perception changes over time - study of developmental trajectory measure: Brain imaging in young children associated with ASD measure: Early data on social perception sex: ALL minimumAge: 3 Months maximumAge: 25 Years stdAges: CHILD stdAges: ADULT facility: Hôpital Necker Enfants Malades city: Paris zip: 75015 country: France name: Nathalie BODDAERT, MD, PhD role: CONTACT phone: +33 1.71.39.65.30 email: nathalie.boddaert@aphp.fr lat: 48.85341 lon: 2.3488 hasResults: False
nctId: NCT06334575 id: 2023-505245-13-00 briefTitle: Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels acronym: 3TR-ICS-COPD overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2025-12 date: 2025-12 date: 2024-03-28 date: 2024-03-28 name: Maria Joyera Rodríguez class: OTHER briefSummary: The 3TR-ICS COPD study is an international, multicentre, randomized, parallel, controlled study that will recruit clinically stable former smokers COPD patients (with no exacerbations in the previous 8 weeks) on treatment with dual long-acting bronchodilators (LABA+LAMA), minimum 8 weeks of usage, not receiving ICS (either naïve or \> 3 months since last usage). The overall objective of this clinical trial is to identify the molecular signatures associated with the molecular response to ICS treatment in patients with COPD stratified by the levels of circulating eosinophils, and the potential influence of the pulmonary microbiome conditions: Chronic Obstructive Pulmonary Disease studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 135 type: ESTIMATED name: Budesonide measure: Significant molecular changes in COPD stratified by their blood eosinophil counts. measure: Significant molecular changes in COPD with different airflow limitation severities. sex: ALL minimumAge: 40 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Philips University of Marburg city: Marburg country: Germany name: Peter Alter role: CONTACT lat: 50.80904 lon: 8.77069 facility: Academisch Ziekenhuis Groningen city: Groningen country: Netherlands name: Marteen van den Berge role: CONTACT lat: 53.21917 lon: 6.56667 facility: Clínic Barcelona city: Barcelona zip: 08036 country: Spain name: Alvar Agustí role: CONTACT lat: 41.38879 lon: 2.15899 facility: Son Espases city: Palma De Mallorca zip: 07120 country: Spain name: Francisco de Borja Cosio role: CONTACT lat: 39.56939 lon: 2.65024 facility: University of Leicester city: Leicester country: United Kingdom name: Christopher Brightling role: CONTACT lat: 52.6386 lon: -1.13169 facility: Imperial College London city: London country: United Kingdom name: Lydia J Finney role: CONTACT lat: 51.50853 lon: -0.12574 hasResults: False
nctId: NCT06334562 id: KY-2023-112 briefTitle: The Clinical Effect of Sugammadex Sodium (Domestic) for Antagonizing Neuromuscular Blockade After Thoracic Surgery overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-01-31 date: 2025-08-31 date: 2024-03-28 date: 2024-03-28 name: The Fourth Affiliated Hospital of Zhejiang University School of Medicine class: OTHER briefSummary: This study aims to compare the use of sugammadex (domestic) and neostigmine for antagonism after thoracic surgery, and observe the effect of sugammadex (domestic) on neuromuscular blockade antagonism after thoracic surgery, in order to provide a basis for optimizing the use of muscle relaxants and their antagonists during anesthesia. conditions: Neuromuscular Blockade studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 80 type: ESTIMATED name: SUGAMMADEX SODIUM 100 Mg in 1 mL name: Neostigmine measure: Muscle relaxation recovery time sex: ALL minimumAge: 19 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06334549 id: LSKY2023-107-01 briefTitle: A Prospective Study of Vasopressor on Cerebral Oxygenation During General Anesthesia overallStatus: RECRUITING date: 2024-03-05 date: 2024-12-05 date: 2024-12-05 date: 2024-03-28 date: 2024-03-28 name: Dalian Municipal Central Hospital class: OTHER briefSummary: The purpose of this study is to investigate whether norepinephrine(N), phenylephrine(P) or ephedrine(E) have different effect on cerebral oxygenation in abdominal surgery with propofol or sevoflurane. conditions: Hypotension Drug-Induced studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 180 type: ESTIMATED name: Ephedrine-P name: Phenylephrine-P name: Norepinephrine-P name: Ephedrine-S name: Phenylephrine-S name: Norepinephrine-S measure: Continual changes in Cerebral Oxygen Saturation measure: Continual changes in systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood pressure (MAP) measure: Continual changes in heart rate (HR) measure: Continual changes in stroke volume (SV) measure: Continual changes in cardiac output (CO) measure: Continual changes in systemic vascular resistance (SVR) sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Dalian Municipal Central Hospital status: RECRUITING city: Dalian state: Liaoning zip: 116033 country: China name: Liping Han, M.D. role: CONTACT lat: 38.91222 lon: 121.60222 hasResults: False
nctId: NCT06334536 id: 0832/66 briefTitle: Multi-country Survey on Violence Against Women Among Medical Staff overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-03 date: 2025-03 date: 2024-03-28 date: 2024-03-28 name: Chulalongkorn University class: OTHER name: Asia and Oceania Federation of Obstetrics and Gynaecology briefSummary: The goal of this observational study is to investigate the knowledge, attitude, and practice (KAP) towards violence against women (VAW) among medical staff in the Department of Obstetrics and Gynecology in Asia and Oceania countries
Participants will be asked to complete the online self-administrated questionnaire. conditions: Violence Against Women studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 400 type: ESTIMATED measure: KAP towards VAW measure: KAP towards support service of VAW sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06334523 id: Volem briefTitle: Ventilation of the Extremely Premature Infants Optimized by Dead Space Washout acronym: Volem overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-12-30 date: 2027-12-31 date: 2024-03-28 date: 2024-03-28 name: Centre Hospitalier Intercommunal Creteil class: OTHER briefSummary: The Continuous Tracheal Gas Insufflation (CTGI) is a ventilation option of conventional ventilation to reduce or even cancel dead space due to respiratory prostheses. This objective is particularly interesting in the smallest preterm infants in which the volume of anatomical dead space due to prostheses is little different from the tidal volume. The principle of this option is to continuously blow an additional flow of 0.2 L/min at tip of endotracheal tube to purge expired CO2 trapped in the prostheses to have a CO2-free volume of gas available for subsequent insufflation. conditions: Extremely Low Birthweight Infant conditions: Continuous Tracheal Gas Insufflation conditions: Medical Device conditions: Lung Protection conditions: Ventilator-Induced Lung Injury studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 144 type: ESTIMATED name: ventilation measure: cumulative duration of non-invasive ventilation periods in living patients measure: The pressure gradient of the ventilation measure: The age at the definitive withdrawal of any ventilatory support (PPS) measure: Definitive weaning age of invasive ventilation measure: Definitive O2 weaning age measure: the death rate measure: The rate of recourse to the HFO measure: The level of pneumothorax measure: The rate of bronchopulmonary dysplasia (BPD) diagnosed measure: Rate of postnatal systemic corticosteroid therapy measure: Duration of exposure to systemic sedatives measure: The cumulative day invasive ventilation measure: Non-programmed extubation rate measure: Rate of secondary blooddstream infection measure: neuroimaging complication measure: Neurodevelopmental monitoring measure: Pulmonary inflammation by cytokine dosage for intubated patients measure: Pulmonary inflammation by cytokine dosage for intubated patients measure: Pulmonary inflammation by cytokine dosage for intubated patients measure: rate of Retinopathy rank >1 measure: severe hypoxemia measure: Additional dose of surfactant sex: ALL minimumAge: 23 Weeks maximumAge: 26 Weeks stdAges: CHILD hasResults: False