hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06289218 id: Treating knee osteoarthritis briefTitle: Kinesio Taping Versus Interferential Current Therapy in Treating Knee Osteoarthritis overallStatus: NOT_YET_RECRUITING date: 2024-06-25 date: 2025-06 date: 2025-09 date: 2024-03-01 date: 2024-03-05 name: Cairo University class: OTHER briefSummary: The purpose of this study will be to compare the combined effect of using Kinesio taping versus interferential current with an exercise program on knee pain, function, knee range of motion, knee muscle strength, and functional mobility in chronic knee osteoarthritis. conditions: Knee Osteoarthritis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 48 type: ESTIMATED name: interferential current name: kinesio taping name: exercise measure: knee flexion range of motion measure: knee extension range of motion measure: quadriceps muscle strength measure: The Western Ontario and McMaster Universities Osteoarthritis Index measure: Timed up and go test sex: ALL minimumAge: 40 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06289205 id: 60/IRB/SLMC/SWL briefTitle: "Comparing Methotrexate Usage Techniques to Prevent Proliferative Vitreoretinopaty After Retinal Detachment Vitrectomy" overallStatus: RECRUITING date: 2024-03 date: 2025-02 date: 2025-05 date: 2024-03-01 date: 2024-03-01 name: University of Health Sciences Lahore class: OTHER briefSummary: This clinical trial, involving participants with rhegmatogenous retinal detachment, aims to compare Methotrexate Usage Techniques in preventing Proliferative Vitreoretinopathy (PVR) after vitrectomy. The study will evaluate the development of PVR, retinal detachment recurrence, and improvement in visual acuity. Participants will undergo retinal detachment surgery using the vitrectomy technique and will be divided into two groups. One group will receive Methotrexate infusion during surgery, while the other will receive repeated Methotrexate injections post-surgery. The researcher will analyze and compare outcomes between the two groups. conditions: Proliferative Vitreoretinopathy studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Using lottery methods patients will be divided into two groups with 60 subjects in each group. Group 1 will be regarded as control group and per operative methotrexate infusion will be used by mixing 75 mg of methotrexate into one litre of BSS solution. Group 2 will be regarded as the study group and will receive 500 µg of intra-silicon oil methotrexate at the end of the surgery and then at 1st, 2nd, 3rd , 4th and 6th post operative weeks. primaryPurpose: PREVENTION masking: SINGLE maskingDescription: This will be a single-blind study in which the subjects will be unaware of the intervention. Blinding will be maintained by ensuring that subjects are unaware of the dosing regimens they are receiving. whoMasked: PARTICIPANT count: 120 type: ESTIMATED name: Methotrexate measure: Development of Proliferative Vitreoretinopathy (PVR) measure: Recurrence of Retinal Detachment measure: Visual Acuity Improvement sex: ALL minimumAge: 20 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sahiwal Medical College & Teaching Hospital, Sahiwal, Pakistan status: RECRUITING city: Sahiwal state: Punjab zip: 57000 country: Pakistan name: Ahmad Z Jamil, FCPS,FRCS role: CONTACT phone: +923334853851 email: ahmadzeeshandr@gmail.com lat: 30.66667 lon: 73.1 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2024-02-24 uploadDate: 2024-02-24T14:05 filename: Prot_SAP_000.pdf size: 182492 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2024-02-24 uploadDate: 2024-02-24T14:06 filename: ICF_001.pdf size: 185782 hasResults: False
nctId: NCT06289192 id: IRB00396489 briefTitle: Testing C-Raven, a Virtual Tobacco Cessation Intervention, in the Community overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-12 date: 2025-06 date: 2024-03-01 date: 2024-03-15 name: Johns Hopkins University class: OTHER name: Maryland Cigarette Restitution Fund briefSummary: To inform a future randomized trial of a virtual counselor led computer delivered intervention for tobacco cessation augmented with community health worker (CHW) support and navigation to lung cancer screening in low-income housing units in Baltimore, the investigators propose to collect data on intervention acceptability and feasibility among individuals in public housing as well as feedback on use of shared decision making when referring for low-dose chest CT (LDCT).
The investigators will conduct a feasibility pilot study of a virtual counselor plus community health worker intervention. With a sample of participants from public housing units (N=15), the investigators will collect data on feasibility of recruitment, intervention engagement and completion, and short-term smoking cessation outcomes. Individuals will be assessed at baseline, 1 month and 3 months. At the end of three months, the investigators will conduct follow up interviews with a subset of pilot participants to collect qualitative data on intervention acceptability. Based on this information, the investigators will make iterative improvements to the combined intervention. conditions: Tobacco Dependence studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 15 type: ESTIMATED name: C-Raven Virtual Tobacco Cessation Counseling name: Nicotine Replacement Product name: Community Health Worker name: Lung Cancer Screening measure: Acceptability and Feasibility measure: Readiness to quit smoking as assessed by The Readiness Ruler measure: Number of Participants that Uptake nicotine replacement therapy measure: Continued use of nicotine replacement therapy measure: Number of quit attempts measure: Number of participants than maintain cessation measure: Number of participants that uptake Quit Line services measure: Participant engagement with community health worker as assessed by number of CHW interactions measure: Participant satisfaction as assessed by study team survey sex: ALL minimumAge: 50 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Chase House Apartments city: Baltimore state: Maryland zip: 21201 country: United States name: Jeanne Clark, MD role: CONTACT phone: 410-614-1135 email: jmclark@jhmi.edu name: Alejandra Ellison-Barnes, MD role: CONTACT phone: 4106141135 email: aelliso6@jhmi.edu lat: 39.29038 lon: -76.61219 facility: Monument East city: Baltimore state: Maryland zip: 21202 country: United States name: Jeanne Clark, MD role: CONTACT phone: 410-614-1135 email: jmclark@jhmi.edu name: Alejandra Ellison-Barnes, MD role: CONTACT phone: 4106141135 email: aelliso6@jhmi.edu lat: 39.29038 lon: -76.61219 facility: Johns Hopkins University School of Medicine city: Baltimore state: Maryland zip: 21205 country: United States name: Jeanne Clark, MD role: CONTACT phone: 410-614-1135 email: jmclark@jhmi.edu name: Alejandra Ellison-Barnes, MD role: CONTACT phone: 4106141135 email: aelliso6@jhmi.edu lat: 39.29038 lon: -76.61219 hasResults: False
nctId: NCT06289179 id: Thyroid and cortisol in sepsis briefTitle: Thyroid and Cortisol Hormone Response to Sepsis overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2026-02-20 date: 2026-10-25 date: 2024-03-01 date: 2024-03-01 name: Assiut University class: OTHER briefSummary: Thyroid and cortisol hormone response to sepsis conditions: Sepsis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 114 type: ESTIMATED measure: Pattern of cortisol level and thyroid function response to sepsis in ICU sex: ALL minimumAge: 18 Years maximumAge: 100 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06289153 id: 23-01182 briefTitle: Internal Bracing Following ACL Reconstruction overallStatus: RECRUITING date: 2024-03-01 date: 2025-02-26 date: 2025-08-26 date: 2024-03-01 date: 2024-03-12 name: NYU Langone Health class: OTHER briefSummary: The purpose of this study is to assess Anterior Cruciate Ligament (ACL) healing through analyzing clinical, radiographic, functional and patient-reported outcomes following ACL reconstruction with quadriceps graft with and without internal bracing. conditions: ACL Injury studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 30 type: ESTIMATED name: Arthrex Internal Brace name: ACL Reconstruction measure: Change from Baseline in 2000 International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Form at Month 6 Post-Operation measure: Change from Baseline in 2000 IKDC Subjective Knee Evaluation Form Score at Month 12 Post-Operation measure: Change from Baseline in Lysholm Knee Scoring System Score at Month 6 Post-Operation measure: Change from Baseline in Lysholm Knee Scoring System Score at Month 12 Post-Operation measure: Change from Baseline in Visual Analogue Scale (VAS) - Pain Score at Month 6 Post-Operation measure: Change from Baseline in Visual Analogue Scale (VAS) - Pain Score at Month 12 Post-Operation sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: NYU Langone Health status: RECRUITING city: New York state: New York zip: 10016 country: United States lat: 40.71427 lon: -74.00597 hasResults: False
nctId: NCT06289140 id: BIOPTERO2 briefTitle: Oral Bioavailability of a New Formulation of Pterostilbene Cocrystal in Comparison With Its Free Form (BIOPTERO2) acronym: BIOPTERO2 overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-04 date: 2024-04 date: 2024-03-01 date: 2024-03-01 name: Fundació Eurecat class: OTHER name: Circe, S.L. briefSummary: The goal of this interventional study is to to evaluate the oral bioavailability of the crystallized form of pterostilbene (ccPT) compared to its commercial free base form (pterostilbene (PT) in healthy volunteers. The main question it aims to answer are:
Researchers will analyze the three postprandial assays to determine which type of ccPT encapsulation provides the highest bioavailability compared to the commercial free base form (PT). conditions: Biological Availability studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: OTHER masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 6 type: ESTIMATED name: Pterostilbene cocrystal (ccPT) - Gelatin capsule name: Pterostilbene free form (PT) name: Pterostilbene cocrystal (ccPT) - Gastro-resistant capsule measure: Bioavailability of Pterostilbene calculated by area under the curve (AUC 0-24) of plasma pterostilbene levels, both free and total. measure: Area under the curve (AUC 0-inf) of plasma pterostilbene levels, both free and total. measure: Relative bioavailability of plasma pterostilbene levels (Frel). measure: Maximum plasma concentration (Cmax) measure: Time for maximum plasma concentration (Tmax) measure: Half-life (T1/2). sex: MALE minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fundació Eurecat city: Reus zip: 43204 country: Spain name: Antoni Caimari, PhD role: CONTACT phone: 0034 977 300 431 email: antoni.caimari@eurecat.org name: Anna Crescenti, PhD role: CONTACT phone: 0034 977 300 431 email: anna.crescenti@eurecat.org lat: 41.15612 lon: 1.10687 hasResults: False
nctId: NCT06289127 id: GO 22/595 briefTitle: Test Properties of Lower Quarter Y-Balance Test: Effect of Verbal Instructions and Focus Techniques overallStatus: COMPLETED date: 2022-07-20 date: 2023-02-02 date: 2023-11-10 date: 2024-03-01 date: 2024-03-04 name: Hacettepe University class: OTHER briefSummary: The Lower Quadrant Y-Balance Test (LQYBT) is a landmark test used in assessing lower extremity performance, determining risk factors for injury, and making return-to-sport decisions. Studies have shown that the individual's focus of attention affects balance. The literature, has shown that the use of external focus is more effective than the use of internal focus in the execution of a movement.Consistent with these findings, the use of an external focus instruction during the LQYBT may lead to achieve more realistic and a higher performance outcome than the test result with standard instructions. The primary aim of this study was to investigate the effects of using different instructions and focusing techniques on test performance on the LQYBT. The secondary aim was to investigate the reliability of the different instructions and focus tests we used for the LQYBT.
Hypothesis of the study that test performance can be further enhanced by differentiating the instructions and focus techniques. A more effective assessment of individual performance may help us to make a more realistic decision to return to sport. conditions: Healthy conditions: Attention Disturbances conditions: Physical Stress studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 2 type: ACTUAL name: Lower Quarter Y Balance Test measure: Investigate the effects of using different instructions and focusing techniques on test performance on the LQYBT. measure: Investigate the reliability of the different instructions and focus tests we used for the LQYBT. sex: ALL minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: Hacettepe University city: Ankara state: Sıhhıye zip: 06430 country: Turkey lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06289114 id: S-20220005 briefTitle: Predictive Utility of a Short-term Improvement in Objectively Measured Physical Activity in Rheumatoid Arthritis (PUSIPA) acronym: PUSIPA overallStatus: RECRUITING date: 2023-09-01 date: 2025-09-01 date: 2025-09-01 date: 2024-03-01 date: 2024-03-01 name: Hospital of South West Jutland class: OTHER briefSummary: SUMMARY Background: Several studies have shown physical activity (PA) to be inversely correlated to disease activity in rheumatoid arthritis (RA) patients. However, it is unclear whether improved PA leads to lower disease activity or if low disease activity predicts improved PA in rheumatoid arthritis patients. Furthermore, it is unknown how fibromyalgia (FM) affects this interaction.
Measurements: RA patients will be divided into two groups depending on their improvement in physical activity after onset of biological treatment. The percentage of time spent in moderate-to-vigorously physical activity (MVPA) i.e., the percentage of time a patient is in motion \[walking, running, bicycling, or swimming\] is measured prior to, one week, and approximately 3 months after biological treatment onset, respectively. The MVPA ratio (MVPA After biological treatment/MVPA Before biological treatment) will divide patients enabling a contrast between two groups: Those with high improvement considering MVPA (after 1 week; the upper tertile of MVPA ratio of the sample) and those without. Treatment response (achieving a disease activity score \< 3.2) after approximately 3 months from baseline will be analyzed as the contrast between groups. conditions: Rheumatoid Arthritis conditions: Fibromyalgia, Secondary conditions: Fatigue conditions: Physical Inactivity studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED measure: MVPA ratio before and after biological therapy measure: Disease activity score (DAS) measure: Fibromyalgia measure: Fatigue measure: Physical activity scores on questionnaire sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Esbjerg Hospital status: RECRUITING city: Esbjerg zip: 6700 country: Denmark name: Philip R Lage-Hansen, MD role: CONTACT phone: +4530114582 email: philip.rask.lage-hansen3@rsyd.dk lat: 55.47028 lon: 8.45187 hasResults: False
nctId: NCT06289101 id: IRB00422008 id: R21HD112617 type: NIH link: https://reporter.nih.gov/quickSearch/R21HD112617 briefTitle: text4FATHER R21: Social Media - Efficacy Trial overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-06 date: 2024-03-01 date: 2024-03-01 name: Johns Hopkins University class: OTHER name: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) briefSummary: This project will be the first to examine the efficacy of a text messaging intervention designed to recruit first-time fathers-to-be using social media across the U.S. to become involved during pregnancy through two months of postnatal age to support infant, mother, and father well-being. conditions: Fathers conditions: Mobile Health conditions: Nuclear Family studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: 2 groups will be enrolled and randomized to receipt or not receipt of the intervention. primaryPurpose: PREVENTION masking: NONE count: 180 type: ESTIMATED name: text4FATHER measure: Change in Self-efficacy as assessed by the Parenting Sense of Competence Scale (PSOC) measure: Karitane Parenting Confidence Scale (KPCS) measure: Fathering Self-Efficacy Scale (FSES) measure: Father Engagement Scale (FES) measure: The Co-Parenting Relationship Scale sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Johns Hopkins Hospital city: Baltimore state: Maryland zip: 21287 country: United States lat: 39.29038 lon: -76.61219 hasResults: False
nctId: NCT06289088 id: E-10840098-772.02-4659 briefTitle: The Effect of an Individually Adapted Lumbosacral Orthosis on Plantar Pressure and Balance acronym: lumbosacral overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-04 date: 2024-05-04 date: 2024-05-04 date: 2024-03-01 date: 2024-03-19 name: Istanbul Medipol University Hospital class: OTHER briefSummary: The aim of this study is to examine the effect of steel underwire lumbosacral orthosis adapted to the individual by the prosthetist orthotist on pain, comfort, plantar pressure, static and dynamic balance in individuals with low back pain. conditions: Orthosis conditions: Low Back Pain, Postural studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Single group, crossover study primaryPurpose: OTHER masking: SINGLE whoMasked: PARTICIPANT count: 30 type: ESTIMATED name: First Intervention name: Second Intervention name: Third Intervention measure: Visual Analog scale measure: Orthosis comfort score measure: Functional Reach Test (FRT) measure: Pedobarographic evaluation measure: Y balance test sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Istanbul Medipol University city: Istanbul country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06289075 id: 23-1096-retro briefTitle: PrognostICate- Study:Prognostication of ICU- and Ventilator- Days Over the Next Years Until 2040 acronym: PrognostICate overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-06-01 date: 2024-12-01 date: 2024-03-01 date: 2024-03-01 name: University Hospital of Cologne class: OTHER name: Johann Wolfgang Goethe University Hospital name: Monash University name: The Alfred name: Albert Einstein College of Medicine name: Montefiore Hospital briefSummary: The Objective of our retrospective multicenter- study is to forecast ICU length of stay (ICULOS) and length of mechanical ventilation (LOMV) in ICU patients of different groups (regarding gender, age group, medical vs surgical admission) worldwide for the next years up to the year of 2040 using statistical forecasting models and historical, national and international ICU databases and population databases. conditions: ICU Admission studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 10000000 type: ESTIMATED name: Intensive Care Unit (ICU) treatment measure: Length of mechanical ventilation measure: Length of ICU stay sex: ALL minimumAge: 1 Day maximumAge: 120 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06289062 id: NACI-CERV-005 briefTitle: Neoadjuvant Chemotherapy Plus Camrelizumab for FIGO Stage IB1 Cervical Cancer overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-12-01 date: 2030-12-01 date: 2024-03-01 date: 2024-03-01 name: Tongji Hospital class: OTHER name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University name: Women Hospital, School of Medicine, Zhejiang University name: Third Military Medical University name: Beijing Friendship Hospital name: Sichuan Cancer Hospital and Research Institute name: Tianjin Medical University name: West China Second University Hospital name: Xiangya Hospital of Central South University name: Qilu Hospital of Shandong University name: Gansu Cancer Hospital name: Zhejiang Cancer Hospital name: Shengjing Hospital name: Anhui Provincial Cancer Hospital briefSummary: This multicenter, prospective clinical trial is designed to enroll PD-L1 expression-positive patients with stage IB1 cervical cancer who desire fertility preservation to undergo neoadjuvant chemotherapy in combination with a PD-1 inhibitor to evaluate the rate of complete pathologic remission, treatment-related adverse events, pregnancy rate, miscarriage rate, preterm birth rate, live birth rate, PFS and OS. conditions: Cervical Cancer conditions: Neoadjuvant Chemoimmunotherapy conditions: Fertility Preservation studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 40 type: ESTIMATED name: Camrelizumab name: Cisplatin name: Nab paclitaxel name: biopsy measure: Pathologic complete response measure: The negative conversion of HPV measure: Pregnancy rate measure: Miscarriage rate measure: Live birth rate measure: Preterm birth rate measure: Adverse Event measure: Surgical complications measure: Change from Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) Physical Function Score measure: Change from Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Symptom Specific Scale for Cervical Cancer (EORTC QLQ-CX24) Score measure: Event-free survival (EFS) measure: Overall survival (OS) sex: FEMALE minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology city: Wuhan state: Hubei zip: 430030 country: China name: Kezhen Li role: CONTACT phone: 086-027-8362 email: tjkeke@126.com name: Jing Chen role: CONTACT phone: 086-027-8362 email: chenjing3223@126.com name: Kezhen Li role: PRINCIPAL_INVESTIGATOR name: Gang Chen role: PRINCIPAL_INVESTIGATOR lat: 30.58333 lon: 114.26667 hasResults: False