hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06271200 id: MG-113-GP-03 briefTitle: Intervention on Metabolism and Related Chronic Diseases overallStatus: NOT_YET_RECRUITING date: 2024-02-20 date: 2026-01-19 date: 2027-12-31 date: 2024-02-21 date: 2024-02-21 name: National Health Research Institutes, Taiwan class: OTHER name: Tri-Service General Hospital name: Chang Gung Memorial Hospital name: National Taiwan University Hospital Hsin-Chu Branch name: Taichung Armed Forces General Hospital briefSummary: This study is a randomized, parallel-group, observer-masked clinical trial. A total of 120 obese participants with MetS will be enrolled. Eligible subjects will be randomly assigned to the ILI group or ULI group with an allocation ratio of 2:1. The ILI group will be instructed to eat in 8 hours while fasting in 16 hours on daily basis over 24 weeks. Furthermore, enhanced daily physical activities with walking more than 10,000 steps will be implemented. The enrolled participants will be instructed to follow a diet with reduction of daily intake of 500 kcals per day. ILI group will be asked to use the Health2Sync mobile app to track self-measured outcomes and daily diet control. The investigators objectively measure step counts for participants of ILI group during 24-week intervention period using a wearable device (Fitbit Inspire 2). Participants are asked to attach the pedometer on their waist belt, except while bathing and sleeping. The ULI group will be instructed to follow habitual meal timing. In addition, all participants of both groups will receive the health education. Anthropometric, sociodemographic data, biochemical variables, and metabolic variables will be measured at baseline and during follow-up visit. DEXA and MRI of abdomen will be measured at baseline and during following up visits. The proposed trial is designed to provide 85% statistical power to detect a significant difference in changes in the metabolic syndrome severity score after reduction \> 5% body weight over 24 weeks. conditions: Metabolic Syndrome studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: This study is a randomized, parallel-group, observer-masked clinical trial. A total of 120 obese participants with MetS will be enrolled. Eligible subjects will be randomly assigned to the ILI group or ULI group with an allocation ratio of 2:1. primaryPurpose: PREVENTION masking: NONE count: 120 type: ESTIMATED name: Intermittent fasting and 10,000 steps per day measure: Change in the metabolic syndrome severity score (Z score) after reduction > 5% body weight from baseline to 24 weeks sex: ALL minimumAge: 20 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Institute of Molecular and Genomic Medicine, National Health Resesarch Institutes city: Zhunan state: Miaoli County zip: 350 country: Taiwan name: Vivian Wang, Master role: CONTACT phone: +886-37-206166 phoneExt: 35374 email: ywwang@nhri.edu.tw lat: 22.57358 lon: 120.54147 hasResults: False
nctId: NCT06271187 id: A-ER-110-507 briefTitle: Dynamic-orthosis Programs for Stroke Hand Function overallStatus: RECRUITING date: 2023-01-22 date: 2024-10-31 date: 2024-12-31 date: 2024-02-21 date: 2024-02-21 name: National Cheng-Kung University Hospital class: OTHER briefSummary: This study aims to investigate the training benefits of modular 3D printed dynamic orthoses on upper limb function in stroke survivors. conditions: Stroke studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 80 type: ESTIMATED name: Dynamic-orthosis name: Traditional stroke occupational therapy training measure: Fugl-Meyer Assessment- Upper Extremity measure: Box and Block Test measure: Motor Activity Log measure: Modified Ashworth scale measure: Upper limb joint range of motion sex: ALL minimumAge: 20 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: National Cheng Kung University status: RECRUITING city: Tainan zip: 701 country: Taiwan name: JER-HAO CHANG, PH.D. role: CONTACT phone: 886-6-2353535 phoneExt: 5912 email: jerhao@ncku.edu.tw lat: 22.99083 lon: 120.21333 hasResults: False
nctId: NCT06271174 id: RC23_0009 briefTitle: Avoid With Locoregional Analgesia Persistant Postoperative Pain In Children acronym: AWA3PASIC overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-05 date: 2026-05 date: 2024-02-21 date: 2024-04-09 name: Nantes University Hospital class: OTHER name: Fondation Apicil briefSummary: Persistent postoperative pain is a substantial pain (scores 4-10 using a 0-10 numeric scale) that develops 3 months after surgery.
The goal is to show the decrease of the incidence of the persistent postoperative pain in the group "locoregional analgesia". conditions: Persistent Postoperative Pain studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 208 type: ESTIMATED name: Carbocaine name: Profofol and/or Suxaméthonium and/or Sévoflurane measure: Persistent Postoperative Pain measure: Screening of neuropathic pain if persistent postoperative pain - 3 months measure: Screening of neuropathic pain if persistent postoperative pain - 6 months measure: Screening of neuropathic pain if persistent postoperative pain - 12 months measure: 1st EN score in immediate post-operative ICU before morphine titration measure: Persistent postoperative pain at 6 months. measure: Persistent postoperative pain at 12 months. measure: Postoperative nausea and vomiting measure: Time in Post Interventional Care Unit measure: Opioïd dose received - Per-operative measure: Opioïd dose received - in Post Interventional Care Unit measure: Opioïd dose received measure: Intravenous Morphine dose received in Post Interventional Care Unit sex: ALL minimumAge: 5 Years maximumAge: 183 Months stdAges: CHILD hasResults: False
nctId: NCT06271161 id: F002 briefTitle: The Effect of Pharyngeal Cooling Applications on Postoperative Throat Pain and Nausea Vomiting overallStatus: COMPLETED date: 2023-01-01 date: 2023-11-01 date: 2024-01-01 date: 2024-02-21 date: 2024-02-21 name: Selcuk University class: OTHER briefSummary: The goal of this observational study is to to evaluate the effects of a throat pack soaked with saline at +4 ºC on postoperative throat pain (POTP) and postoperative nausea and vomiting (PONV) in dental surgical procedures performed under general anesthesia. The main questions it aims to answer are: 1. How long can we keep the pharyngeal mucosa cold using tampons and cold wash solutions? 2. Does cooling the pharyngeal mucosa reduce the incidence of postoperative sore throat and nausea and vomiting? conditions: Postoperative Pain conditions: Postoperative Nausea and Vomiting conditions: Throat, Sore conditions: Anesthesia studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 84 type: ACTUAL measure: The incidence of postoperative sore throat and noise vomiting was investigated in dental surgery involving the application of cooling to the pharyngeal area, particularly when a throat pack was used. measure: Intraoperative change in nasopharyngeal temperature from baseline (ºC ), intraoperative opioid usage (mcg), postoperative analgesic usage (mg),antiemetic usage(mg) and any adverse events due to throat pack were recorded. sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Funda Arun city: Selçuklu state: Konya zip: 42000 country: Turkey lat: 37.8842 lon: 32.49222 hasResults: False
nctId: NCT06271148 id: Mutah University id: Myah REC/133/2023 type: REGISTRY domain: Mutah university school of medicine briefTitle: Career and Lifestyle Among Female Surgeons in Jordan overallStatus: COMPLETED date: 2023-02-03 date: 2023-12-17 date: 2023-12-31 date: 2024-02-21 date: 2024-02-21 name: Mohammad Abu-Jeyyab class: OTHER briefSummary: A study conducted to evaluate the female surgeons in Jordan from different lifestyle conditions: Surgery conditions: Lifestyle studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 224 type: ACTUAL name: Interview measure: Career and Lifestyle Among Female Surgeons in Jordan measure: Working Hours measure: Sex Bias measure: inadequate mentorship measure: having 30 days of leave measure: salary sex: FEMALE stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Mutah University city: Al-Karak zip: 61710 country: Jordan lat: 31.16368 lon: 35.76204 hasResults: False
nctId: NCT06271135 id: LU20170508 briefTitle: Assessing the Quality of Life of Patients With Rosacea overallStatus: COMPLETED date: 2017-05-08 date: 2018-11-30 date: 2018-11-30 date: 2024-02-21 date: 2024-02-21 name: Medical University of Bialystok class: OTHER name: University of Lomza briefSummary: The study population consisted of 160 patients (123 women and 37 men) with rosacea, who agreed to participate in this study. Patients were qualified for the study among people visiting the cosmetic studio in Choroszcz in the period from June 2017 to November 2018, based on the diagnosis of a dermatologist and cosmetologist. The cosmetic intervention was performed using CAPILLARY REPAIR SERUM (30ml). Study participants completed self-reported questionnaire and standardized questionnaires. conditions: Rosacea studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 160 type: ACTUAL name: CAPILLARY REPAIR SERUM 30ml measure: Elements influenced on quality of life of participants with rosacea measure: Self-reported questionnaire measure: Dietary Questionnaire measure: The Physical Activity Questionnaire measure: DLQI (Dermatology Life Quality Index) measure: SWLS (Satisfaction With Life Scale) measure: BDI (Beck Depression Inventory) sex: ALL minimumAge: 30 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Medical University of Bialystok city: Białystok zip: 15-089 country: Poland lat: 53.13333 lon: 23.16433 hasResults: False
nctId: NCT06271122 id: COMPET-1 briefTitle: Identification of Explanatory Factors for the Lack of Muscle Strength Gain Following a Pulmonary Rehabilitation Program in COPD Patients overallStatus: RECRUITING date: 2024-01-18 date: 2025-05-16 date: 2025-05-16 date: 2024-02-21 date: 2024-02-21 name: Korian class: OTHER briefSummary: Chronic Obstructive Pulmonary Disease (COPD) is a chronic respiratory disease associated with various comorbidities, including muscle weakness (MW), which is very worrying due to its negative impact on patients' quality of life and survival. To address this issue, muscle strengthening is incorporated into pulmonary rehabilitation programs. However, its effectiveness is unclear, as although there is an average improvement in muscle strength, one in two patients does not show a clinically relevant improvement. To understand this non-response, it is crucial to examine the effect of muscle strengthening programs on the two main determinants of force production: the muscle and the central command. Muscle adaptations following a muscle strengthening program are well-documented, showing improvements in muscle function (cross-sectional area, lean mass, etc.). Conversely, only one study has investigated central adaptations after a muscle strengthening program, clearly demonstrating a lack of effect.
The investigators hypothesize that patients showing no improvement in muscle strength after pulmonary rehabilitation (non-responders) have a significantly lower level of voluntary activation before starting the program compared to responding patients (responders). conditions: Chronic Obstructive Pulmonary Disease studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 36 type: ESTIMATED name: Voluntary activation assessed by magnetic stimulation measure: Central voluntary activation assessed by transcranial magnetic stimulation (TMS) measure: Muscle excitability assessed by femoral magnetic stimulation (FMS) measure: Contractile properties assessed by femoral magnetic stimulation (FMS) measure: Corticospinal excitability assessed by transcranial magnetic stimulation (TMS) measure: Intra-cortical inhibitions transcranial magnetic stimulation (TMS) measure: Voluntary activation assessed by femoral magnetic stimulation (FMS) sex: ALL minimumAge: 40 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Clinique du Souffle La Vallonie status: RECRUITING city: Lodève zip: 34700 country: France name: Nelly Heraud, PhD role: CONTACT phone: +33467888491 email: nelly.heraud@clariane.fr name: Nicolas Oliver, MD role: PRINCIPAL_INVESTIGATOR lat: 43.71667 lon: 3.31667 hasResults: False
nctId: NCT06271109 id: Soh-Med-24-01-04MD briefTitle: Short Term Surgical Outcomes of Anatomical Versus Non Anatomical Laparoscopic Liver Resection for Liver Tumors overallStatus: ENROLLING_BY_INVITATION date: 2021-12-01 date: 2025-06-01 date: 2025-06-01 date: 2024-02-21 date: 2024-02-21 name: Sohag University class: OTHER briefSummary: aimed to discuss the short term surgical outcomes of Anatomical versus Non anatomical laparoscopic Liver resection for Liver tumors. conditions: Liver Neoplasms studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: OTHER count: 50 type: ESTIMATED name: Anatomical laparoscopic liver resection for liver neoplasms name: Non-Anatomical laparoscopic liver resection for liver neoplasms measure: complete resection of the neoplasm measure: residual liver tissue measure: recurrence rate sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Sohag University city: Sohag country: Egypt lat: 26.55695 lon: 31.69478 hasResults: False
nctId: NCT06271096 id: 638/ADR/KMC briefTitle: Intramuscular Midazolam Versus Intravenous Diazepam for Acute Seizure in Children overallStatus: COMPLETED date: 2019-11-01 date: 2022-11-01 date: 2024-01-01 date: 2024-02-21 date: 2024-02-23 name: Arooj Khan class: OTHER briefSummary: IM-midazolam in acute seizures, whenever IV cannulation is not possible. It is easy to administer and can be used in prehospital settings as IV cannulation requires experience, especially in pediatric age group. Moreover, the transit time to the hospital can be prolonged in our areas which can delay the treatment if intravenous cannulation is considered. More studies are required to assess the feasibility of administering IM-midazolam in a prehospital setting to control acute seizures conditions: Seizures studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: This study was a randomized controlled trial carried out between November 2019 to November 2022 in the Pediatric department of Khyber Teaching Hospital. A total of 150 children who presented to the emergency department with seizures were enrolled in this study via consecutive sampling. This study was approved by the Ethical Review primaryPurpose: TREATMENT masking: NONE count: 150 type: ACTUAL name: Intra muscular Midazolam name: Intravascular Diazepam measure: Fits Controlled sex: ALL minimumAge: 3 Months maximumAge: 5 Years stdAges: CHILD facility: Khyber Teaching Hospital city: Peshawar zip: 25000 country: Pakistan lat: 34.008 lon: 71.57849 hasResults: False
nctId: NCT06271070 id: 2023-R23 briefTitle: Analysis of Correlation Between Skin Carotenoid Level and Basic Indicators of Health Status Related to Lifestyle in Vietnamese: An Observational Study overallStatus: RECRUITING date: 2024-01-16 date: 2024-05-31 date: 2024-12-31 date: 2024-02-21 date: 2024-02-21 name: KAGOME CO., LTD. class: INDUSTRY name: Dr. Binh_Teleclinic - Branch of E2E Solution Company Limited briefSummary: To clarify the relationship between vegetable intake and lifestyle-related disease in Vietnam, we measure skin carotenoid levels and basic indicators of health status related to lifestyle and analyze the correlation between them. This is an important study that can lead to dietary suggestions for preventing lifestyle-related diseases in Vietnam. conditions: Lifestyle Risk Reduction studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 300 type: ESTIMATED name: Non-intervention measure: Skin carotenoid level measure: Blood markers of lifestyle-related diseases measure: BMI measure: Body fat percentage measure: Blood pressure measure: Questionnaire sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Dr. Binh_Teleclinic - Branch of E2E Solution Company Limited status: RECRUITING city: Hanoi zip: 11612 country: Vietnam name: Nguyen Thuy Lan, Doctor role: CONTACT phone: +84 243 622 7799 lat: 21.0245 lon: 105.84117 hasResults: False
nctId: NCT06271057 id: CARMOD briefTitle: Golcadomide Post-CAR T-cell in R/R Aggressive Large B-cell Lymphoma Patients With High Risk of Relapse overallStatus: NOT_YET_RECRUITING date: 2024-04-22 date: 2026-01-15 date: 2027-10-20 date: 2024-02-21 date: 2024-02-21 name: The Lymphoma Academic Research Organisation class: OTHER name: Lymphoma Study Association briefSummary: This study is an open-label, multicenter, proof of concept, phase 2 trial. Patients will be recruited over 18 months. Safety analysis will be performed with a stop of the enrollment after 3 patients have either 1 complete treatment cycle or permanently discontinued treatment whichever occurs first.
The primary objective of the study is to estimate the efficacy of golcadomide administered post-anti-CD19 CAR T-cell infusion, Efficacy determination will be based upon the primary endpoint of complete metabolic response (CMR) rate at 3 months after infusion of anti-CD19 CAR T-cell assessed by study investigator. conditions: Diffuse Large B-cell Lymphoma Refractory conditions: Refractory Primary Mediastinal Large B-Cell Lymphoma conditions: Refractory Transformed B-cell Non-Hodgkin Lymphoma conditions: Refractory High Grade B-Cell Lymphoma studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 65 type: ESTIMATED name: golcadomide measure: Complete metabolic response rate (CMR rate) measure: Objective response rate (ORR) measure: Objective response rate (ORR) measure: Complete response rate (CRR) measure: Duration of response (DR) measure: Event-free survival (EFS) measure: Progression-free survival (PFS) measure: Time To Next anti-Lymphoma Treatment (TTNLT) measure: Overall survival (OS) measure: Incidence of Adverse Events and Serious Adverse events sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hopital Henri Mondor city: Créteil zip: 94010 country: France lat: 48.78333 lon: 2.46667 facility: Chu Dijon Bourgogne city: Dijon zip: 21000 country: France lat: 47.31667 lon: 5.01667 facility: Chu de Grenoble city: La Tronche zip: 38700 country: France lat: 45.20429 lon: 5.73645 facility: Chru de Lille city: Lille zip: 59037 country: France lat: 50.63297 lon: 3.05858 facility: Institut Paoli Calmettes city: Marseille zip: 13273 country: France lat: 43.29551 lon: 5.38958 facility: Chu de Montpellier city: Montpellier zip: 34090 country: France lat: 43.61092 lon: 3.87723 facility: Chu de Nantes city: Nantes zip: 44093 country: France lat: 47.21725 lon: -1.55336 facility: Hopital Saint-Louis city: Paris zip: 75475 country: France lat: 48.85341 lon: 2.3488 facility: Chu de Bordeaux city: Pessac zip: 33604 country: France lat: 44.81011 lon: -0.64129 facility: Chu Pontchaillou city: Rennes zip: 35033 country: France lat: 48.11198 lon: -1.67429 facility: Centre Henri Becquerel city: Rouen zip: 76038 country: France lat: 49.44313 lon: 1.09932 facility: Iuct Oncopole city: Toulouse zip: 31059 country: France lat: 43.60426 lon: 1.44367 facility: Chu Brabois city: Vandœuvre-lès-Nancy zip: 54511 country: France lat: 48.65 lon: 6.18333 hasResults: False
nctId: NCT06271044 id: RAILESS briefTitle: a. Reducing Radioiodine Treatment in Papillary Thyroid Cancer. RAILESS overallStatus: ACTIVE_NOT_RECRUITING date: 2014-10 date: 2024-12 date: 2027-12-31 date: 2024-02-21 date: 2024-02-21 name: Helsinki University Central Hospital class: OTHER briefSummary: To study if its is safe to reduce the amount of postoperative treatments in those patients, who have been operated on because of a low-risk intrathyroidal papillary thyroid cancer with diameter of 11-20mm, and in whom postoperative thyroglobulin levels are of low level. conditions: to Omit Radioiodine Treatment Safely in Patients With Low -Risk Papillary Thyroid Cancer With Seize of 11-20mm studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Patients with low risk papillary thyroid cancer either received a radioiodine treatment according to the normal Finnish treatment schedule or were schedulded for only follow-up . primaryPurpose: OTHER masking: NONE maskingDescription: No masking. count: 61 type: ACTUAL name: With radioiodine treatment name: With postoperative radioiodine treatment measure: Event free situation during follow-up event free /disease free sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06271031 id: LHS0211 briefTitle: Process Mapping and Data Collection to Inform a Computer Simulation Model of Hospitalised Patients With Bloodstream Infection, Sepsis and Systemic Infection acronym: CSM-BSI overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-12-31 date: 2026-03-31 date: 2024-02-21 date: 2024-02-21 name: Liverpool University Hospitals NHS Foundation Trust class: OTHER_GOV briefSummary: The goal of this study is to create a computer simulation of patients with bloodstream infection to understand how changes in healthcare policies and resources affect patient treatment. This simulation will help doctors and health-care decision makers make better choices in treating these patients and avoid overusing antibiotics that can lead to antibiotic resistance. Antibiotic resistance is when bacteria can't be killed by antibiotics anymore. Participants will not receive treatments as this is an observational study, but the study will involve:
* A 30-day observational study to observe patient treatment for bloodstream infections. conditions: Sepsis conditions: Bloodstream Infection conditions: Bacteraemia studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: RETROSPECTIVE count: 100 type: ESTIMATED measure: Generation of a software simulation model that is fine tuned to the observed data. measure: Exploration of the performance of the model in different hypothesised scenarios. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT typeAbbrev: Prot_ICF hasProtocol: True hasSap: False hasIcf: True label: Study Protocol and Informed Consent Form date: 2023-10-10 uploadDate: 2023-11-14T09:05 filename: Prot_ICF_000.pdf size: 2058603 hasResults: False
nctId: NCT06271018 id: GMIO-2024-0001 briefTitle: TocILizumab in aorTitis in GCA (TILT) acronym: TILT overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-10-01 date: 2028-04-01 date: 2024-02-21 date: 2024-02-21 name: GMIOFrance class: UNKNOWN briefSummary: This is a french multicenter observational study assessing safety and efficacy of biosimilar of Tocilizumab in Giant Cell Arteritis (GCA) with active aortitis, including 14 reference centers from the Groupe d'Etude Français des vascularites des gros vaisseaux (GEFA).
Giant Cell Arteritis (GCA), formerly known as temporal arteritis, is the most common form of systemic vasculitis in patients aged ≥ 50 years. GCA is defined by granulomatous arteritis that affects large#sized and medium#sized blood vessels with a predisposition to affect the cranial arteries. Aortitis accounted for more than 50% of GCA patients with the new imaging techniques. Aortitis is typically diagnosed using imaging tests such as magnetic resonance imaging (MRI) or Computed Tomography (CT) scans. Aortitis is an inflammation of the aorta, leading to a range of symptoms such as fever, weight loss, fatigue, and chest pain. In severe cases, aortic aneurysms or aortic dissection can occur, which can be life-threatening.