hackint0sh/New-Dataset huggingface dataset:
While applying both scales, care will be taken to ensure that children, parents and observers do not see each other's evaluations and are not influenced by each other. In this way, the child, parent and independent observer will score blindly before and after the procedure. whoMasked: PARTICIPANT count: 147 type: ESTIMATED name: Coolsense and Buzzy measure: Faces Pain Scale- Revised (FPS-R) measure: Children's Fear Scale (CFS) measure: Heart rate measure: Oxygen saturation measure: Respiratory rate measure: Blood pressure sex: ALL minimumAge: 6 Years maximumAge: 12 Years stdAges: CHILD hasResults: False
nctId: NCT06369636 id: myucesu briefTitle: Comparison of El-Ganzouri Risk Index and Airway Ultrasonographic Evaluation in Thyroid Surgery overallStatus: COMPLETED date: 2023-06-01 date: 2023-10-31 date: 2024-01-28 date: 2024-04-17 date: 2024-04-17 name: Ankara City Hospital Bilkent class: OTHER briefSummary: The primary purpose of this prospective observational study was to compare these tests used to predict difficult intubation in patients undergoing thyroid surgery. Secondarily; By comparing these tests, we aim to find the test that best predicts difficult intubation and to determine the incidence of difficult intubation in patients who will undergo thyroid surgery. conditions: Thyroid Surgery conditions: Difficult Intubation studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 120 type: ACTUAL name: Thyroid Surgery measure: Compare EGRI and airway ultrasonographic parameters measure: Find which is the best test predicts difficult intubation measure: Finding the incidence of difficult intubation in thyroid surgery sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ankara Bilkent City Hospital city: Ankara state: Çankaya zip: 06800 country: Turkey lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06369623 id: IRB2023-00466 briefTitle: Monetary Incentive Delay Task for Probing Reward-related Neural Processes acronym: MID overallStatus: RECRUITING date: 2024-04-06 date: 2028-11-30 date: 2028-11-30 date: 2024-04-17 date: 2024-04-17 name: Stony Brook University class: OTHER briefSummary: 150 males and 150 females ages 14-17 years-old will be enrolled in an observational, longitudinal study. There are three planned in-person visits: a baseline assessment, an 18-month follow-up, and a 36-month follow-up. The in-person visits will include assessment of substance use and other individual differences (e.g., reward function, psychiatric history), neuromelanin-sensitive MRI, as well as functional brain activation collected while the participant is at rest (resting-state fMRI) and while the participant completes a Monetary Incentive Delay task. Subjects will also be asked to complete past 90-day substance use assessments remotely every 90 days for 36 months. conditions: Adolescent Development studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 300 type: ESTIMATED name: Monetary Incentive Delay Task measure: Functional Brain Activation from Monetary Incentive Delay Task sex: ALL minimumAge: 14 Years maximumAge: 17 Years stdAges: CHILD facility: Stony Brook Medicine status: RECRUITING city: Stony Brook state: New York zip: 11794 country: United States name: Greg Perlman, PhD role: CONTACT phone: 631-638-1922 email: greg.perlman@stonybrookmedicine.edu name: Roman Kotov, PhD role: CONTACT name: Greg Perlman, PhD role: PRINCIPAL_INVESTIGATOR lat: 40.92565 lon: -73.14094 hasResults: False
nctId: NCT06369610 id: GMROA2256 id: NCI-2024-03020 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: 22-012591 type: OTHER domain: Mayo Clinic Institutional Review Board id: GMROA2256 type: OTHER domain: Mayo Clinic in Arizona briefTitle: Risk Stratified De-escalated Hormone Therapy With Radiation Therapy for the Treatment Prostate Cancer overallStatus: RECRUITING date: 2024-04-22 date: 2027-04-22 date: 2027-04-22 date: 2024-04-17 date: 2024-04-24 name: Mayo Clinic class: OTHER briefSummary: This phase II trial tests how well risk based de-escalated hormone therapy (i.e., fewer treatments) with radiation works in treating patients with prostate cancer. Androgen deprivation therapy (ADT), such as gonadotropin-releasing hormone analogs (LHRH) and abiraterone acetate (Zytiga), lower the amount of the male hormone, testosterone, made by the body. This may help kill or stop the growth of tumor cells that need testosterone to grow. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Research has shown that long-term ADT is beneficial for patients with high-risk prostate cancer. However, there are few studies that determine ADT treatment based on risk factors. Giving risk based de-escalated ADT with radiation therapy may be as effective as giving more ADT in treating high-risk prostate cancer. conditions: Oligometastatic Prostate Carcinoma conditions: Prostate Adenocarcinoma studyType: INTERVENTIONAL phases: PHASE2 allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 64 type: ESTIMATED name: Abiraterone Acetate name: Biospecimen Collection name: Computed Tomography name: Gonadotropin-releasing Hormone Analog name: Magnetic Resonance Imaging name: Positron Emission Tomography name: Questionnaire Administration name: Radiation Therapy measure: Hormonal domain scores sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mayo Clinic in Arizona status: RECRUITING city: Scottsdale state: Arizona zip: 85259 country: United States name: Clinical Trials Referral Office role: CONTACT phone: 855-776-0015 email: mayocliniccancerstudies@mayo.edu name: Carlos E. Vargas, M.D. role: PRINCIPAL_INVESTIGATOR lat: 33.50921 lon: -111.89903 hasResults: False
nctId: NCT06369597 id: Robot2024 briefTitle: A Randomized Controlled Trial of the Safety and Efficacy of Robotic Telesurgery Versus Laparoscopic Surgery overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2024-12-31 date: 2025-03-31 date: 2024-04-17 date: 2024-04-17 name: Sun Yat-sen University class: OTHER briefSummary: This is a randomized controlled trial that will be preceded by a safety trial focusing on the safety and efficacy of robotic telesurgery. The hypothesis is that robotic telesurgery has a non-inferior primary endpoint event rate to local laparoscopic surgery. conditions: Liver Cancer conditions: Renal Cancer conditions: Rectal Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 177 type: ESTIMATED name: Robotic telesurgery name: Laparoscopic surgery measure: Surgical complication measure: Surgical time (min) measure: Intraoperative blood loss (mL) measure: Postoperative hospitalization days measure: Physician satisfaction measure: Remote metrics sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: First Affiliated Hospital, Sun Yat-Sen University city: Guangzhou state: Guangdong zip: 510080 country: China name: Kuang Ming, PhD role: CONTACT phone: 008687755766 phoneExt: 8576 email: kuangm@mail.sysu.edu.cn lat: 23.11667 lon: 113.25 hasResults: False
nctId: NCT06369584 id: PEPAD briefTitle: Prone Position During ECMO in Pediatric Patients With Severe ARDS acronym: PEPAD overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-01 date: 2025-07-01 date: 2024-04-17 date: 2024-04-17 name: Seventh Medical Center of PLA General Hospital class: OTHER name: Gansu Provincial Maternal and Child Health Care Hospital name: Xian Children's Hospital name: Henan Provincial People's Hospital name: People's Hospital of Guangxi name: Guangdong Provincial People's Hospital briefSummary: In 2023, the second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) updated the diagnostic and management guidelines for Pediatric Acute Respiratory Distress Syndrome (PARDS). The guidelines do not provide sufficient evidence-based recommendations on whether prone positioning ventilation is necessary for severe PARDS patients. However, the effectiveness of Extracorporeal Membrane Oxygenation (ECMO) in treating severe PARDS has been fluctuating around 70% according to recent data from Extracorporeal Life Support Organization (ELSO).
In 2018, the Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) study group conducted a retrospective analysis and concluded that ECMO does not significantly improve survival rates for severe PARDS. However, this retrospective study mainly focused on data from North America, with significant variations in annual ECMO support cases among different centers, which may introduce bias. With advancements in ECMO technology and materials, ECMO has become safer and easier to operate. In recent years, pediatric ECMO support technology has rapidly grown in mainland China and is increasingly being widely used domestically to rescue more children promptly.
nctId: NCT06369571 id: IRB00439268 briefTitle: Improving Cardiovascular Health Risks in Adults With Epilepsy on a Modified Atkins Diet overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2027-01 date: 2027-12 date: 2024-04-17 date: 2024-04-17 name: Johns Hopkins University class: OTHER name: American Heart Association briefSummary: Ketogenic diet therapies (KDTs) emphasize high fat and very low carbohydrate intake and help to control seizures in adults who fail to respond to medications. However, KDT use can lead to increased cholesterol levels in some adults with epilepsy (AWE). Treatments that can reverse elevations in cholesterol observed with long-term KDT use without compromising diet adherence and seizure control are needed. The proposed study will explore the feasibility and safety of diet modification and statin use to lower cholesterol in this population. Study findings will help guide doctors utilizing KDTs in adults with epilepsy on how to approach managing elevations in cholesterol. conditions: Epilepsy conditions: Dyslipidemia studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 22 type: ESTIMATED name: Atorvastatin 10mg name: Modification of dietary fat composition measure: Diet adherence as assessed by 3 day food records measure: Statin Adherence measure: LDL Change measure: Change in weekly seizure frequency measure: Seizure severity questionnaire score measure: Frequency of adverse events measure: Blood ketone change sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06369558 id: BiruniUniversi briefTitle: Plyometric Exercise Training in Athletes With Chronic Low Back Pain overallStatus: COMPLETED date: 2024-01-01 date: 2024-04-04 date: 2024-04-04 date: 2024-04-17 date: 2024-04-17 name: Ugur Cavlak class: OTHER name: Biruni University briefSummary: The aim of this study is to examine the effectiveness of plyometric exercise training in the athletes with chronic low back pain. 32 professional volunteer athletes participated in the study. conditions: Low Back Pain, Mechanical studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized controlled trial primaryPurpose: TREATMENT masking: NONE count: 32 type: ACTUAL name: PLYOMETRIC TRAINING name: CLASSIC PHYSIOTHERAPY PROGRAM measure: VISUAL ANALOG SCALE measure: OSWESTRY DISABILITY INDEX measure: SIT AND REACH TEST measure: VERTICAL JUMP TEST measure: FLAMINGO BALANCE TEST measure: SHUTTLE RUNNİNG (20 MİN.) measure: MANUAL MUSCLE STRENGTH TEST sex: ALL minimumAge: 18 Years maximumAge: 25 Years stdAges: ADULT facility: Faculty of Health Sciences in Biruni University city: İ̇stanbul state: Zeytinburnu zip: 34010 country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06369545 id: BiruniUniver briefTitle: Chronic Pelvic Pain Syndrome in Males overallStatus: RECRUITING date: 2024-01-01 date: 2024-04-04 date: 2024-08-15 date: 2024-04-17 date: 2024-04-17 name: Biruni University class: OTHER briefSummary: The aim of this study is to evaluate the effectiveness of ESWT (Extracorporeal Shock Wave Therapy) and TENS (Transcutaneous Electrical Nerve Stimulation) in individuals diagnosed with chronic pelvic pain syndrome and treated with medication. The study was organized as a randomized controlled trial. The sample size is 30 patients suffering from chronic pelvic pain syndrome. conditions: Pelvic Pain Syndrome studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized Controled Trial primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 38 type: ESTIMATED name: EXERCISE name: TENS name: ESWT measure: VISUAL ANALOUGE SCALE measure: National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) measure: ALGOMETER measure: Hospital Anxiety and Depression Scale- HAD measure: Nottingham Health Profile-NHP measure: Digital Muscle Testing measure: Flexibility Measurements measure: ROM Assessments measure: Lasegue Test sex: MALE minimumAge: 20 Years maximumAge: 40 Years stdAges: ADULT facility: Faculty of Health Sciences in Biruni University status: RECRUITING city: İ̇stanbul state: Zeytinburnu zip: 34010 country: Turkey name: UGUR CAVLAK, Prof., PhD. role: CONTACT phone: 00905324519644 email: ucavlak@biruni.edu.tr lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06369532 id: ONZ-2023-0460 briefTitle: Combination of Neurostimulation and Psychotherapy to Stop Worrying overallStatus: RECRUITING date: 2024-03-06 date: 2026-02-20 date: 2027-02-20 date: 2024-04-17 date: 2024-04-17 name: University Hospital, Ghent class: OTHER briefSummary: This study aims to investigate whether the combination of transcranial Direct Current Stimulation (tDCS) and cognitive-behavioral therapy (CBT) is more effective for treating repetitive negative thinking (RNT) in patients with the symptom of high rumination. High ruminators will be included (Group1, active tDCS-CBT group; Group2, sham tDCS-CBT group). All patients will receive active or sham tDCS. conditions: Active tDCS conditions: Sham tDCS studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE maskingDescription: Participants will be allocated into two groups randomly (using a code). The psychotherapist, the study managers and the patients will not be aware of treatment allocation. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 85 type: ESTIMATED name: Active tDCS name: Sham tDCS measure: the therapeutic effect of the combination therapy for repetitive negative thinking measure: the consolidation effect of tDCS on CBT measure: Change of neuroimaging data sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University Hospital Ghent status: RECRUITING city: Ghent state: East-Flanders zip: 9000 country: Belgium name: Chris Baeken, Prof. role: CONTACT name: Josefien Dedoncker, M.Sc. role: CONTACT lat: 51.05 lon: 3.71667 hasResults: False
nctId: NCT06369519 id: 2023#17-23 briefTitle: Optimization of Management for Sporadic Bilateral Renal Cell Carcinoma overallStatus: COMPLETED date: 2000-01-01 date: 2020-12-31 date: 2020-12-31 date: 2024-04-17 date: 2024-04-17 name: Peking University First Hospital class: OTHER briefSummary: Sporadic bilateral renal cell carcinoma (BRCC) is a rare situation of RCC. The treatment for BRCC is controversial and there is a lack of authoritative guidelines about the management of BRCC. The goal of this cohort study is to identify prognostic factors, construct predictive nomograms, and optimize management for sporadic BRCC patients. The main questions it aims to answer are:
Researchers will analysis the prognostic factors and compare the prognosis of BRCC patients receiving different treatments. conditions: Kidney Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 3677 type: ACTUAL name: Surgery treatment or local tumor destruction. measure: Overall survival (OS) measure: Cancer-specific survival (CSS) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Peking University First Hospital city: Beijing state: Beijing zip: 100034 country: China lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06369506 id: PYO.DIS.1904 Protocol ID:4467 briefTitle: Evaluation of Gingival Thickness Measurement at Different Anatomical Landmarks overallStatus: COMPLETED date: 2022-09-10 date: 2023-08-05 date: 2023-12-17 date: 2024-04-17 date: 2024-04-17 name: Ondokuz Mayıs University class: OTHER briefSummary: In this study, the point at which gingival thickness (GT) should be measured was investigated. Measurements were made from three different points. It was classified as thin and thick in two ways, according to the average of these three different points and the point corresponding to the base of the gingival groove, which is frequently used in the literature. And these two classifications were compared. conditions: Gingival Thickness studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Participants were divided into two different classifications: "thin" and "thick". The first classification was made by measuring the GT of the point corresponding to the base of the gingival sulcus. GT was defined as thin if ≤1 mm, and thick if \>1 mm. In the second classification, GT was measured from three different points. And according to the average GT of three points, they were equally classified as "thin" and "thick". primaryPurpose: SCREENING masking: NONE count: 50 type: ACTUAL name: GTmeasurement measure: Examining the sensitivities and sensitivities of two different gingival phenotype classifications based on three-point average GT measurement and single-point measurement using Receiver Operating Characteristic Analysis (ROC). measure: Examining the agreement of GT measurements at three different points in 50 patients, 1195 teeth, using Kappa analysis. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ondokuz Mayis University Faculty of Dentistry Department of Periodontology city: Samsun zip: 55000 country: Turkey lat: 41.27976 lon: 36.3361 hasResults: False
nctId: NCT06369493 id: OMUKAEK: 2022/210 briefTitle: Examining The Relationship Between Gingival Thickness and Tooth and Gingival Parameters overallStatus: COMPLETED date: 2022-09-01 date: 2023-12-01 date: 2023-12-18 date: 2024-04-17 date: 2024-04-17 name: Ondokuz Mayıs University class: OTHER briefSummary: This study aims to assess whether there is a valid correlation between the identified multiple clinical and morphometric parameters and the gingival thickness. conditions: Gingival Thickness studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 50 type: ACTUAL measure: Evaluation of the correlation between KGW, CW, CL PH parameters of GT measured in "mm" with a digital caliper with 0.001 mm precision in 1200 teeth in 50 participants using Spearman correlation analysis. measure: Evaluation of the effect of GT on keratinized gingival width, measured in "mm" by digital caliper with a precision of 0.001 mm, both by binary logistic regression analysis of 50 participants. measure: Examining the effect of age and gender of 50 participants on the gingival thickness measured in mm using binary logistic regression analysis. measure: Evaluation of researcher reliability by ICC (Intra-Class Correlation Coefficient) in 10 participants in 2 weeks sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ondokuz Mayis University Faculty of Dentistry Department of Periodonthology city: Samsun zip: 55200 country: Turkey lat: 41.27976 lon: 36.3361 hasResults: False
nctId: NCT06369480 id: Journal-nr.: R-23057752 briefTitle: Prognostic Factors for Survival in Patients With Cholangiocarcinoma overallStatus: RECRUITING date: 2024-02-01 date: 2024-08-31 date: 2024-08-31 date: 2024-04-17 date: 2024-04-17 name: Rigshospitalet, Denmark class: OTHER briefSummary: The objective of this retrospective study is to determine the survival rates of CCA patients based on different therapeutic approaches. Additionally, we aim to investigate the risk factors associated with poor survival within a cohort of patients treated over a seven-year period across four Danish hospitals. We anticipate that our findings could provide additional evidence for clinical decision-making, improve patient outcomes, and contribute to the knowledge in the field. conditions: Cholangiocarcinoma studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 2000 type: ESTIMATED name: Resection/Ablation of tumor name: Palliative chemotherapy name: Neoadjuvant chemotherapy name: Stereotatic radiotherapy name: Best supportive care measure: Aim I measure: Aim II sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Rigshospitalet status: RECRUITING city: Copenhagen zip: 2100 country: Denmark name: Hans-Christian Pommergaard, MD DMSc PhD role: CONTACT email: hans-christian.pommergaard@regionh.dk lat: 55.67594 lon: 12.56553 hasResults: False
nctId: NCT06369467 id: R5458-668-ALG-2219 id: 2024-511032-27-00 type: REGISTRY domain: EU CT Number briefTitle: Short-Term Linvoseltamab Treatment, on Top of Chronic Dupilumab Treatment, for Adults With Severe Immunoglobulin E (IgE)-Mediated Food Allergy overallStatus: NOT_YET_RECRUITING date: 2024-04-12 date: 2026-04-24 date: 2026-04-24 date: 2024-04-17 date: 2024-04-17 name: Regeneron Pharmaceuticals class: INDUSTRY briefSummary: This study is researching an experimental drug called linvoseltamab when combined with another drug called dupilumab. The study is focused on patients who have IgE-mediated food allergy. If the patient has an allergy, the immune system overreacts to an allergen (eg, certain foods such as peanuts, milk, shellfish) by producing antibodies called IgE. IgE antibodies are released by cells such as plasma cells. These antibodies and allergen bind to other cells that release chemicals, causing an allergic reaction. The aim of the study is to see how safe and tolerable linvoseltamab is when combined with dupilumab.
* How much study drug(s) is in the blood at different times conditions: Food Allergy studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: NONE count: 6 type: ESTIMATED name: linvoseltamab name: dupilumab measure: Incidence of treatment-emergent adverse events (TEAEs) measure: Severity of TEAEs measure: Incidence of adverse event of special interest (AESIs) measure: Severity of AESIs measure: Incidence of serious adverse events (SAEs) measure: Severity of SAEs measure: Absolute change in the serum concentration of total IgE over time measure: Percent change in the serum concentration of total IgE over time measure: Time to reach unquantifiable total serum IgE concentration measure: Time to reach baseline level and/or the lower limit of the normal ranges of serum IgG measure: Time to reach baseline level and/or the lower limit of the normal ranges of serum immunoglobulin M (IgM) measure: Time to reach baseline level and/or the lower limit of the normal ranges of serum immunoglobulin A (IgA) measure: Incidence of participants with unquantifiable concentrations of serum total IgE measure: Absolute change in the serum concentration of food allergen-specific IgE measure: Percent change in the serum concentration of food allergen-specific IgE measure: Time to reach unquantifiable food allergen-specific serum IgE levels sex: ALL minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT hasResults: False