hackint0sh/New-Dataset huggingface dataset:
The inclusion characteristics of third molars will also be analyzed, to see the links between typology and inclusion. The principal hypothesis is no significant difference in third molar inclusion patterns in relation to skeletal divergence. conditions: Impacted Third Molar Tooth studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: RETROSPECTIVE count: 80 type: ESTIMATED name: Radiographic measurement measure: Distance between the occlusal plane and the second molar measure: Angle of the third molar sex: ALL minimumAge: 15 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06320652 id: CUHospital briefTitle: Implementation and Evaluation of Telemedicine in Cardiac Rehabilitation overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-12-31 date: 2027-08-31 date: 2024-03-20 date: 2024-04-19 name: Copenhagen University Hospital, Hvidovre class: OTHER name: Hvidovre University Hospital briefSummary: The overall aim is to develop and test the effect of a tailored patient and family focused cardiac tele rehabilitation intervention on health literacy by comparing it to standard care. Furthermore, to evaluate health-related quality of life, family support, and how the patients experience the communication and relationship with outpatient clinic nurses. conditions: Cardiac Rehabilitation studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: First, all willing patients who are offered cardiac rehabilitation will comprise the control group. Following a period of implementing the adapted co-created cardiac telerehabilitation intervention. Patients in the control group have access to standard care at the cardiac outpatient clinic program comprising standard center-based cardiac rehabilitation. Patients in the intervention group will, in addition to standard care, be offered an individually tailored family-focused cardiac telerehabilitation developed through a co-creative process. primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 140 type: ESTIMATED name: Cardiac telerehabilitation (video consultation and home monitoring) measure: Health Literacy Questonnaire measure: The European Quality of life five dimensions questionnaire measure: The Iceland-Family Perceived Support Questionnaire measure: The eHealth Literacy Questionnaire sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06320639 id: UGustaveEiffel briefTitle: DRIVing Simulator and People With NeuroCognitive Disorders acronym: DRIVS-NCD overallStatus: RECRUITING date: 2023-10-03 date: 2026-10-10 date: 2026-10-10 date: 2024-03-20 date: 2024-03-20 name: University Gustave Eiffel class: OTHER name: Hospices Civils de Lyon briefSummary: The ageing of the population is leading to an increasing number of older drivers on the roads. At the same time, the proportion of older people with pathological ageing and neurocognitive disorders (NCD) is increasing. In terms of road safety, this raises the question of whether these drivers should continue to drive or not. People with NCDs may not be aware of the presence, extent and progression of their cognitive impairment and the impact it can have on daily life, including driving.
* Individuals' driving performance and awareness of driving ability are lower in the presence of major NCDs compared to minor NCDs. conditions: Neurocognitive Disorders studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 150 type: ESTIMATED measure: Awareness score of driving ability measure: Driving performance variables measured by the driving simulator sex: ALL minimumAge: 50 Years maximumAge: 95 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hôpital des Charpennes status: RECRUITING city: Villeurbanne zip: 69100 country: France name: Marion Giroux, PhD role: CONTACT phone: 0472432372 email: marion.giroux@chu-lyon.fr lat: 45.76667 lon: 4.88333 hasResults: False
nctId: NCT06320626 id: 22-571 briefTitle: Pharmacokinetic-guided Dosing of Emicizumab acronym: DosEmi overallStatus: RECRUITING date: 2022-09-08 date: 2026-03 date: 2026-08 date: 2024-03-20 date: 2024-03-20 name: Kathelijn Fischer class: OTHER name: Erasmus Medical Center name: Amsterdam University Medical Center name: Leiden University Medical Center name: Radboud University Medical Center name: Maastricht University Medical Center name: University Medical Center Groningen name: HagaZiekenhuis name: Dutch Society of Haemophilia Patients briefSummary: The goal of this multicentre, prospective, open-label, cross-over clinical study is to determine whether individualized PK-guided dosing of emicizumab is non-inferior to conventional dosing of emicizumab in the prevention of bleeding in congenital haemophilia A patients. conditions: Hemophilia A With Inhibitor conditions: Hemophilia A Without Inhibitor conditions: Hemophilia A, Severe conditions: Adolescent conditions: Child conditions: Adult studyType: INTERVENTIONAL phases: PHASE4 allocation: NON_RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: * PK-guided dosing - Intervention group (12M): Subjects with emicizumab concentration of ≥ 40 μg/mL will receive individualized PK-guided dose reduction of emicizumab targeted at a Ctrough of 30μg/mL. The validated population PK model is based on published population PK and PK/PD modelling studies. (9,10,15)
nctId: NCT06320613 id: KYLL20240117-2 briefTitle: Effect of Implementing Snap-needle Therapy Combined With Ginger Paste During Anesthesia Recovery on the Recovery of Gastrointestinal Function After Gynecologic Laparoscopy overallStatus: RECRUITING date: 2024-03-20 date: 2024-09-20 date: 2024-09-20 date: 2024-03-20 date: 2024-03-20 name: Weifang Medical University class: OTHER name: Weifang People's Hospital briefSummary: The aim of this study was to investigate the effect of implementing snap-needle therapy combined with ginger paste during anesthesia recovery on the recovery of gastrointestinal function after gynecological laparoscopy. conditions: Gastrointestinal Motility conditions: Postoperative Nausea and Vomiting studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 150 type: ESTIMATED name: Acupuncture therapy name: Ginger Acupuncture Point Patch measure: Postoperative nausea and vomiting measure: Postoperative nausea and vomiting measure: Postoperative nausea and vomiting measure: Postoperative nausea and vomiting measure: Postoperative nausea and vomiting measure: Postoperative nausea and vomiting measure: Abdominal distention measure: Abdominal distention measure: Abdominal distention measure: Abdominal distention measure: Abdominal distention measure: Abdominal distention measure: Time to first flatus measure: Postoperative pain response measure: Postoperative pain response measure: Postoperative pain response measure: Postoperative pain response measure: Postoperative pain response measure: Postoperative pain response measure: Consumption of postoperative analgesic measure: Consumption of postoperative rescue antiemetic measure: Time to first defecation sex: FEMALE minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Lin Cheng status: RECRUITING city: Weifang state: Shandong zip: 261000 country: China name: Lin Cheng, B.S role: CONTACT phone: 17667404256 email: 1318216353@qq.com lat: 36.71 lon: 119.10194 hasResults: False
nctId: NCT06320600 id: PDC briefTitle: Precision Medicine of Diabetes Program in China acronym: PDC overallStatus: RECRUITING date: 2023-07-01 date: 2028-12 date: 2028-12 date: 2024-03-20 date: 2024-03-20 name: Second Xiangya Hospital of Central South University class: OTHER briefSummary: The prevalence of diabetes has been increasing year by year. According to the International Diabetes Federation (IDF) statistics in 2021, the global number of people with diabetes has reached 537 million. The patient population is large and heterogeneous, and precise diagnosis and treatment of diabetes patients have been a focus of attention. The objective of this study is to clarify the current status of precision classification and diagnosis of diabetes patients through retrospective and prospective cohort studies, and to establish a model for precision classification and diagnosis of diabetes, improving the accuracy of diabetes classification and diagnosis; based on big data of precision medicine for diabetes patients and follow-up cohorts, to establish precise diagnostic, therapeutic, and predictive methods for diabetes; and through multi-omics data analysis, to explore the potential pathogenesis of diabetes, explaining the heterogeneity of patients, and guiding individualized treatment for patients. conditions: Diabetes studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: OTHER count: 120000 type: ESTIMATED name: no intervention measure: The currency analysis of diabetes classification measure: To establish a model for predicting diabetic retinopathy measure: To establish a model for predicting diabetic kidney disease measure: To establish a model for predicting diabetic neuropathy measure: To establish a model for hypoglycemic therapy sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: the Second Xiangya Hospital status: RECRUITING city: Changsha state: Hunan zip: 410010 country: China name: Shuting Yang role: CONTACT phone: 15200863137 email: yang_shting@163.com lat: 28.19874 lon: 112.97087 hasResults: False
nctId: NCT06320587 id: AEŞH-EK1-2023-508 briefTitle: The Effect of Kangaroo Care on Parents' Perceived Parenting Self-Efficacy, Infant Attachment and Newborn Vital Signs overallStatus: RECRUITING date: 2024-02-01 date: 2024-03-30 date: 2024-05-30 date: 2024-03-20 date: 2024-03-20 name: Saglik Bilimleri Universitesi class: OTHER briefSummary: This study was planned to determine the effect of kangaroo care applied by parents of premature newborns in the neonatal intensive care unit on the newborn's vital signs, perceived parenting self-efficacy level and attachment to the baby. conditions: Kangaroo Care conditions: Fathers conditions: Mother-Infant Interaction conditions: Premature Infant studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: SUPPORTIVE_CARE masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 100 type: ESTIMATED name: Kangaroo care practice by both mother and father name: Kangaroo care practice only mother measure: Mother-To-Infant Bonding Scale measure: Perceived Mother Parenting Self-Efficacy Scale measure: Postnatal Paternal-Infant Attachment Questionnaire measure: Perceived Father Parenting Self-Efficacy Form measure: Physiological parameters of the premature infant: peak heart rate (BPM) measure: Physiological parameters of the premature infant: oxygen saturation (%) measure: Physiological parameters of the premature infant: body temperature (°C) measure: Physiological parameters of the premature infant:Respiration rate (RPM) sex: ALL minimumAge: 28 Weeks maximumAge: 37 Weeks stdAges: CHILD facility: Ankara Etlik City Hospital status: RECRUITING city: Ankara zip: 06170 country: Turkey name: Gönül Kurt, Assoc.prof. role: CONTACT phone: 90(312)304 phoneExt: 3934 email: gonul.kurt@sbu.edu.tr name: Meryem Büşra Borazan role: CONTACT email: busrabrzn.bb@gmail.com name: Meryem Büşra Borazan role: SUB_INVESTIGATOR name: Gönül Kurt, Assoc.prof. role: PRINCIPAL_INVESTIGATOR lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06320574 id: 2023-16880 briefTitle: Nurses' Competence in Gastric Ultrasound acronym: SKILLS-1 overallStatus: NOT_YET_RECRUITING date: 2024-03-14 date: 2024-04-20 date: 2024-08-01 date: 2024-03-20 date: 2024-03-20 name: Radboud University Medical Center class: OTHER briefSummary: The goal of this observational cohort study is to investigate gastric ultrasound skills in surgical nurses. The main question it aims to answer is:
* and formative assessments during training sessions scanning healthy volunteers by participants and examiners (expert gastric ultrasonographers). conditions: Gastric Content conditions: Healthy Volunteers studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 8 type: ESTIMATED measure: Number of required training sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06320561 id: 23485_StrIMuC12 briefTitle: Muscular Changes in the First 12 Weeks After Stroke. acronym: StrIMuC12 overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2027-01 date: 2027-05 date: 2024-03-20 date: 2024-03-20 name: Vrije Universiteit Brussel class: OTHER name: University Ghent name: Research Foundation Flanders briefSummary: The investigators will use 3D freehand ultrasound to investigate changes in muscle morphology of the paretic m. rectus femoris and m. gastrocnemius medialis during the first 3 months after stroke. Additionally, 2D ultrasound and surface EMG will be synchronized to examine muscle activation and morphological changes resulting from this activation. Clinical tests will be conducted on the same test occasions to objectify lower limb impairment and gait recovery. As such, the investigators will explore the relationship between the muscle specific changes and functional recovery. conditions: Stroke studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED name: Longitudinal prospective cohort study measure: Functional Ambulation Categories (FAC)-score measure: Muscle volume measure: Cross-sectional area (CSA) measure: Physiological cross-sectional area (pCSA) measure: Muscle tickness measure: Fascicle length measure: Muscle length measure: Tendon length measure: Pennation angle measure: Echo Intensity measure: Dynamic muscle morphology measure: Change in cross-sectional area measure: Change in fascicle length measure: Average root mean square (RMS) measure: Peak root mean square (RMS) measure: Muscle strength measure: Spasticity measure: Lower limb motor impairment measure: Spatiotemporal gait parameters measure: Gait quality measure: TWIST-score measure: Knee extension strength measure: Balance sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06320548 id: 0724/2018 briefTitle: The Efficacy of Preoperative Low-residue Diet on Postoperative Ileus Following Cesarean Section overallStatus: COMPLETED date: 2018-10-01 date: 2020-11-30 date: 2020-12-02 date: 2024-03-20 date: 2024-03-20 name: University of Roma La Sapienza class: OTHER briefSummary: The aim of the present study was to evaluate the efficacy of preoperative low-residue diet on postoperative ileus in women undergoing elective cesarean section. It is a surgeon-blind, randomized controlled trial enrolling pregnant women at ≥39 weeks of gestation undergoing elective cesarean section. Patients were preoperatively randomized to receive either low-residue diet (arm A) or free diet (arm B) starting from three days before surgery. The primary outcome was the postoperative ileus at 24 hours after surgery. The secondary outcomes were the postoperative pain (assessed through VAS scale), the quality of the surgical field (scored using a 5-point scale, from poor to excellent), postoperative complications, and the length of hospital stay. Perioperative data were collected and compared between groups. conditions: Cesarean Section Complications studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 166 type: ACTUAL name: Low-residue diet name: Free diet measure: Number of participants who have passage of flatus within the first 24 hours after caesarean section. measure: Postoperative pain measure: Postoperative complications measure: Quality of the surgical field sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sapienza University of Rome city: Rome country: Italy lat: 41.89193 lon: 12.51133 hasResults: False
nctId: NCT06320535 id: VAC096 briefTitle: A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™ overallStatus: RECRUITING date: 2024-04 date: 2026-04 date: 2027-04 date: 2024-03-20 date: 2024-03-20 name: University of Oxford class: OTHER name: Bill and Melinda Gates Foundation name: University Hospitals Bristol and Weston NHS Foundation Trust briefSummary: This is a phase I clinical study that aims to assess the safety and immunogenicity of a novel, escalating dose regimen of R21/Matrix-M™ in healthy, malaria-naïve adults. conditions: Malaria,Falciparum studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 36 type: ESTIMATED name: R21/Matrix M™ (Group 1) name: R21/Matrix M™ (Group 2) name: R21/Matrix M™ (Group 3) name: Fine needle aspiration (FNA) measure: To compare the safety of R21/Matrix-M™ administered in an escalating dose, multi prime vaccination schedule with a standard prime-boost regimen in healthy UK adults measure: To compare the safety of R21/Matrix-M™ administered in an escalating dose, multi prime vaccination schedule with a standard prime-boost regimen in healthy UK adults measure: To compare the humoral immunogenicity of R21/Matrix-M™ administered in an escalating dose, multi-prime vaccination schedule with a standard prime-boost regimen in healthy UK adults measure: To assess the relationship between vaccination schedule and humoral immune response in participants vaccinated with R21/Matrix-M™ administered in escalating dose, multi-prime vaccination schedules compared with a standard prime-boost regimen sex: ALL minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Centre for Clinical Vaccinology and Tropical Meducine, Churchill Hospital, University of Oxford status: RECRUITING city: Oxford state: Oxfordshire zip: OX3 7LE country: United Kingdom name: Volunteer Recruitment Co-ordinator role: CONTACT phone: 01865611386 email: vaccinetrials@ndm.ox.ac.uk lat: 51.75222 lon: -1.25596 facility: University Hospitals Bristol and Weston NHS Foundation Trust status: NOT_YET_RECRUITING city: Bristol zip: BS2 8HW country: United Kingdom name: Rajeka Lazarus, DPhil FCRPath role: CONTACT email: rajeka.lazarus@uhbristol.nhs.uk name: Rajeka Lazarus, DPhil FRCPath role: PRINCIPAL_INVESTIGATOR lat: 51.45523 lon: -2.59665 hasResults: False
nctId: NCT06320522 id: R82053/RE002 briefTitle: Exogenous Ketosis in a Fed and a Fasted State overallStatus: RECRUITING date: 2023-02-15 date: 2024-05 date: 2024-05 date: 2024-03-20 date: 2024-03-20 name: University of Oxford class: OTHER briefSummary: The kinetics of circulating βHB following ingestion of the ketone monoester are dependent on several variables that determine the balance between appearance into, and disappearance from, the bloodstream. These dynamics have been well characterised in fasted humans but in the real world the ketone monoester is likely to be ingested in a fed state, pertinently within athletic spheres consumption would proceed a substantial high-carbohydrate meal. Within this, it is unclear how metabolism under exogenous ketosis might be affected in a fed versus fasted state.
Participants will be asked to consume either the ketone monoester drink or a placebo drink when fasted and when having previously consumed a meal. conditions: Ketosis conditions: Exogenous Ketosis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: BASIC_SCIENCE masking: SINGLE whoMasked: PARTICIPANT count: 12 type: ESTIMATED name: Ketone Monoester name: Placebo measure: Plasma β-hydroxybutyrate (βHB) kinetics measure: Plasma glucose kinetics measure: Postprandial de novo lipogenesis (DNL) measure: Plasma biochemistry measure: Very low-density lipoprotein-triglyceride (VLDL-TG) fatty acid composition measure: Breath acetone measure: Urine volume measure: Urine composition measure: Indirect calorimetry measure: Subjective measures of appetite measure: Subjective measures of gastrointestinal distress sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Oxford Centre for Diabetes, Endocrinology, and Metabolism (OCDEM) status: RECRUITING city: Oxford state: Oxfordshire zip: OX3 7LE country: United Kingdom name: Leanne Hodson, PhD role: CONTACT phone: 01865 857224 email: leanne.hodson@ocdem.ox.ac.uk name: Leanne Hodson, PhD role: PRINCIPAL_INVESTIGATOR name: Adam Isherwood, MSc role: SUB_INVESTIGATOR lat: 51.75222 lon: -1.25596 hasResults: False
nctId: NCT06320509 id: 49RC23_0417 briefTitle: Interest of Urinary Oxygen Partial Pressure (PO2u) in Predicting the Onset or Recovery of Acute Renal Failure During Shock States - OXYpi Study acronym: OXYpi overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-04 date: 2026-07 date: 2024-03-20 date: 2024-03-20 name: University Hospital, Angers class: OTHER_GOV briefSummary: Shock state is defined as an acute, life-threatening, circulatory failure with impaired tissue oxygenation (or tissue hypoxia). The cause of the shock state can be septic, anaphylactic, hypovolemic or cardiogenic. Its management is based on etiological treatment and replacement of organ failures. Acute kidney injury (AKI) may be lead by renal hypoxia. Acute kidney injury is frequent in patients admitted to intensive care unit (ICU) and associated with an increased mortality. Serum creatinine is the reference biological marker in the diagnosis of Acute kidney injury. However, its use is limited by a delayed increase in plasma creatinine level in relation to the causal renal agression, at a time when renal tissue damage may already be established. Thus, the identification of a biological marker making it possible to estimate renal hypoxia continuously during a shock could allow us to identify early a situation at risk of evolving into Acute kidney injury.
nctId: NCT06320496 id: IRR-FLAVIGNY-2021-2 briefTitle: Evaluation of the Effect of a Physical Activity Recovery Stay overallStatus: RECRUITING date: 2022-03-22 date: 2024-12 date: 2025-03 date: 2024-03-20 date: 2024-04-09 name: Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est class: OTHER briefSummary: A WHO study in 2020 revealed that 81% of adolescents (aged 11-17) do not respect the recommendation of one hour of moderate physical activity per day. In the context of disability, many factors impose limits on physical activity. While the pathology itself induces limitations and restrictions (prolonged sitting time, assisted movement, etc.), organizational constraints also apply to both children and parents, who have to divide their time between work, school and therapeutic care, which is sometimes numerous and varied over the course of a single week. These limitations generate stress and fatigue, and prolonged sedentary periods lead children with chronic illnesses, rare diseases or disabilities into a process of physical deconditioning. The accumulation of sedentary time is detrimental to cardiovascular and metabolic health.
To combat this deconditioning, the 2008 National Physical Activity and Sport Plan (PNAPS) sets out the main guidelines for treatment and implementation. The plan explains that "for patients with chronic illnesses, rare diseases or disabilities, the aim is to encourage care and guidance towards Adapted Physical Activity (APA). The attending physician will be able to identify local therapeutic education programs, rehabilitation services and "sport-santé" offers, to improve access for these patients to supervised local programs". In addition, the plan suggests "developing APA programs in healthcare establishments to enable people with chronic illnesses, rare diseases or disabilities to access health education incorporating practical sessions".