hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06354816 id: V 2.0, 07Feb2024 briefTitle: VENLID: The Application of a 10%-Lidocaine Spray Prior to the Insertion of a Peripheral Intra-venous Catheter in Female Adults acronym: VENLID overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-05 date: 2024-05 date: 2024-04-09 date: 2024-04-09 name: Krankenhaus Barmherzige Schwestern Linz class: OTHER briefSummary: Volunteers are invited to undergo 4 insertions of a peripheral intra-venous 18-gauge catheter (PIVC); 2 insertions at the the start of the study on the plantar side of the hand/vessel at the dorsum manus, 2 insertions after 2-10 hours into the forearm/cubita with and without application of a 10-% lidocaine spray (5 hubs of xylocaine 10%-pump spray; AstraZeneca BV, Zoetermeer, The Netherlands) prior to the insertion of the PIVC. conditions: Pain studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: prospective, randomized, double-blind, controlled trial primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 40 type: ESTIMATED name: Xylocaine 10% pump spray name: Saline solution isotonic 0.9% NaCl measure: To demonstrate a reduction of pain caused by PIVC rated by Numerical Rating Scale (NRS), after application of a 10% lidocaine spray- Separately measured for the plantar side of the hand/vessel at the dorsum manus, and for the forearm/cubita measure: To measure pain caused by PIVC rated by NRS in the dominant vs. non-dominant arm measure: To measure pain caused by PIVC rated by NRS at the plantar side of the hand/vessel at the dorsum manus vs. at the forearm/cubita measure: To measure the correlation between pain caused by PIVC rated by NRS and the anticipated pain rated by NRS measure: To measure the correlation between pain caused by PIVC rated by NRS and the anticipated difficulty by the operator to insert the PIVC measure: To measure pain rated by NRS depending on success measure: To describe success rates and compare it measure: To measure the correlation between PCS and pain caused by PIVC rated by NRS sex: FEMALE minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT hasResults: False
nctId: NCT06354803 id: KafrelsheikhU 30 briefTitle: Effect of Pezzi Ball on Balance in Pregnant Women overallStatus: COMPLETED date: 2023-03-02 date: 2024-02-02 date: 2024-03-03 date: 2024-04-09 date: 2024-04-09 name: Kafrelsheikh University class: OTHER briefSummary: The effect of kinaesthetic training on performance and postural stability during pregnancy and 2 weeks postpartum conditions: Postural Stability studyType: INTERVENTIONAL phases: PHASE2 phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: 45 participants with gestational age below 28 weeks primaryPurpose: SUPPORTIVE_CARE masking: QUADRUPLE maskingDescription: The drawing procedure was conducted by a researcher without disclosure to the participants, ensuring unbiased allocation. Moreover, both the assessor and statistician remained blinded throughout the assessment period, unaware of the group assignments. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 45 type: ACTUAL name: proprioceptive training measure: change of postural stability sex: FEMALE minimumAge: 25 Years maximumAge: 30 Years stdAges: ADULT facility: Faculty of physical therapy kafrelshiekh university city: Kafr Ash Shaykh state: Kafrelshiekh zip: 6850001 country: Egypt lat: 31.11174 lon: 30.93991 hasResults: False
nctId: NCT06354790 id: NatHis LAMA2 briefTitle: Natural History Study of Children With LAMA2-related Dystrophies acronym: LAMA2 overallStatus: NOT_YET_RECRUITING date: 2024-06-15 date: 2027-06-14 date: 2027-12-31 date: 2024-04-09 date: 2024-04-09 name: Institut de Myologie, France class: OTHER name: Association Française contre les Myopathies (AFM), Paris briefSummary: The goal of this natural history study is to characterize the disease course, characteristics in paediatric population of LAMA2-RD (related dystrophies) patients.
* Biomarkers conditions: Merosin Deficient Congenital Muscular Dystrophy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 40 type: ESTIMATED name: Motor evaluations name: Cognitive assessment name: Pulmonary function test name: Cardiac evaluation name: Quality of life name: Spine X Ray name: Muscular MRI name: Biomarkers collection and analysis measure: Change in Motor function Measurement (MFM32) score measure: Change in Motor Milestone Checklist measure: Change in Revised Upper Limb Module (RULM) score measure: Change in grip strength measured by dynamometer tool measure: Change in pinch strength measured by dynamometer tool measure: Change in arm flexion/extension strength measured by dynamometer tool measure: Change in 6 Minutes Walking Test measure: Change in 4 Stairs Climbing Test (4SCT) measure: Change in 10m Walking Test measure: Change in Rise from Floor Test measure: Change in patient's Forced Vital Capacity (FVC) results measure: Change in patient's Peak Cough Flow (PCF) results measure: Change in patient's Maximum Expiratory Pressure (MEP) results measure: Change in patient's Maximal Inspiratory Pressure (MIP) results measure: Change in patient's Sniff Nasal Inspiratory Pressure (SNIP) results measure: Change in patient's muscle fat replacement measured by Magnetic Nuclear Resonance measure: Change in patient's cross-sectional area of the residual muscle measured by MNR measure: Change in Wechsler Preschool and Primary Scale of Intelligence-IV (WPPSI-IV) results measure: Change in Wechsler Intelligence Scale for Children-V (WISC-V) results measure: Change in PedsQL questionnaire results measure: Change in CGI-S questionnaire results measure: Change in CGI-I questionnaire results measure: Change in Faces pain rating scale results measure: Change in Fatigue Severity Scale results measure: Change in ACTIVLIM questionnaire results measure: Change in Egen Klassifikation Scale Version 2 (EK2) results measure: Change in Caregiver burden questionnaire (LMDIS) results sex: ALL minimumAge: 2 Years maximumAge: 15 Years stdAges: CHILD facility: Centre de Référence GNMH, Pédiatrie Hôpital Raymond-Poincaré city: Garches country: France name: Isabelle BOSSARD role: CONTACT name: Marta GOMEZ, MD role: PRINCIPAL_INVESTIGATOR lat: 48.84226 lon: 2.18232 facility: Service de MPR pédiatrique L'Escale - HCL city: Lyon country: France name: Manel SAIDI role: CONTACT name: Carole VUILLEROT, MD role: PRINCIPAL_INVESTIGATOR lat: 45.74848 lon: 4.84669 facility: Département de neuropédiatrie Pôle Femme Mère Enfant CHU de Montpellier - Hôpital Gui de Chauliac city: Montpellier country: France name: Léa THEVENET role: CONTACT name: Ulrike WALTHER-LOUVIER, MD role: PRINCIPAL_INVESTIGATOR lat: 43.61092 lon: 3.87723 facility: Plateforme d'essais cliniques pédiatriques iMotion city: Paris country: France name: Dominique DUCHENE role: CONTACT name: Andreea SEFERIAN, MD role: PRINCIPAL_INVESTIGATOR lat: 48.85341 lon: 2.3488 hasResults: False
nctId: NCT06354777 id: EVERCOOL AF briefTitle: REView of ProcEdural FactoRs and Outcomes After Atrial Fibrillation Ablation With Active Esophageal COOLing: A Sub-Study of the REAL AF Registry acronym: EVERCOOL AF overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2024-11-30 date: 2024-12-30 date: 2024-04-09 date: 2024-04-09 name: Heart Rhythm Clinical and Research Solutions, LLC class: OTHER name: Attune Medical briefSummary: This is a multi-center sub-study examining the effectiveness of active esophageal cooling on subjects undergoing left atrial ablation for symptomatic Paroxysmal Atrial Fibrillation or Persistent Atrial Fibrillation. conditions: Atrial Fibrillation studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 312 type: ESTIMATED name: Ablation Procedure measure: To measure procedural efficacy after atrial fibrillation ablation in patients treated with active esophageal cooling. measure: To measure procedural efficacy after atrial fibrillation ablation in patients treated with active esophageal cooling. measure: To measure long term safety after atrial fibrillation in patients treated with active esophageal cooling. measure: Patient reported outcomes in patients treated with active esophageal cooling. measure: Physician reported outcome post procedure with active esophageal cooling. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06354764 id: 8780-UC1 briefTitle: Propensity to Hospitalize Patients From the ED in European Centers. acronym: eCREAM-UC1 overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2025-09 date: 2026-09 date: 2024-04-09 date: 2024-04-11 name: Mario Negri Institute for Pharmacological Research class: OTHER name: Astir S.r.l. name: Centre Hospitalier Universitaire Vaudois name: Orobix Life S.r.l. name: Fondazione Bruno Kessler briefSummary: The peer-to-peer comparison means center-to-center comparison, which requires adjusting for possible differences among centers to be fair and convincing. The first step to reach this goal is to develop a predictive model that accurately estimates each patient's probability of being admitted, starting from clinical conditions and boundary variables. Such a model would make it possible to calculate, for each ED, the expected hospitalization rate; that is, the hospitalization rate that would have been observed if the ED had behaved like the average of the EDs that provided the data to build the model itself. Comparing the observed hospitalization rate in the single ED with the expected rate derived from the model provides a rigorous method of comparing the department with the average performance, taking into account the characteristics of the patients treated and the conditions under which the ED operated. In other words, the predictive model represents the benchmark against which each ED is evaluated. conditions: Emergency Medicine studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 162000 type: ESTIMATED name: no intervention measure: Create two separate databases measure: Multivariable models measure: Adjusted comparison sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06354751 id: 327236 briefTitle: Maternity Care Experiences of Asylum-seeking and Refugee Women in Scotland acronym: MACAWS overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2025-04-20 date: 2025-07-01 date: 2024-04-09 date: 2024-04-09 name: University of Aberdeen class: OTHER briefSummary: The International Organisation of Migration reports that over half (52.4%) of international migrants in Europe are women. Evidence suggests that women with immigrant backgrounds often struggle to access healthcare across the world. Among migrant women, asylum-seeking and refugee women face higher risks of poor pregnancy and birth outcomes, including babies with low birth weight, physical and/or mental health problems or death related to pregnancy and/or childbirth. Previous studies have focused on immigrant women's experiences of care during pregnancy and birth and did not differentiate between asylum seekers, refugees, and economic migrants. This can make it difficult to compare studies accurately. This PhD study focuses on asylum-seeking and refugee women, using the definitions provided by the United Nations. Asylum-seeking women refer to women who seek protection in a country other than their own and are waiting for a decision on their status. Asylum seekers become refugees once their application has been processed and accepted.
A scoping review was conducted to understand the experiences of asylum-seeking and refugee women accessing maternity care in the UK, with a focus on Scotland. The review found that all studies that focused on the experiences of asylum-seeking and refugee women accessing maternity care were mainly based in England. The review identified the presence of specialist migrant services in maternity settings in Scotland and across the UK, but there was no information on their implementation or impact on women's outcomes. Additionally, there is limited evidence in the UK on the perceptions of healthcare professionals providing care to asylum-seeking and refugee women.
This PhD aims to close this gap in research by exploring this area more deeply in Scotland through mixed-methods studies of surveys with asylum-seeking and refugee women and interviews with maternity care leaders, policymakers, maternity healthcare professionals, and asylum-seeking and refugee women. conditions: Refugee conditions: Asylum-seeking Women conditions: Maternity studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: OTHER count: 300 type: ESTIMATED measure: Exploring and understanding asylum-seeking and refugee women's experiences of maternity care in Scotland. measure: Evidence of healthcare professionals' experiences of providing maternity care for asylum-seeking and refugee women in Scotland. measure: Identification of the successful components of specialist migrant maternity services in Scotland. measure: Identification of gaps between care pathways and practice (implementation gap) and how this affects the quality of maternity care and women's experiences of maternity services measure: Information for policymakers on approaches needed to improve maternity care for refugee and asylum-seeking women at local and national levels. sex: FEMALE minimumAge: 16 Years maximumAge: 50 Years stdAges: CHILD stdAges: ADULT hasResults: False
nctId: NCT06354738 id: S66928 briefTitle: Improving Endometrial Cancer Assessment by Combining Genomic Profiling and Surgical Assessment acronym: EUGENIE overallStatus: RECRUITING date: 2023-01-16 date: 2028-11-01 date: 2028-11-01 date: 2024-04-09 date: 2024-04-17 name: University Hospital, Gasthuisberg class: OTHER name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS name: University Medical Centre Maribor briefSummary: EUGENIE is a prospective multicentre interventional study, focused on improving endometrial cancer (EC) assessment by combining the new technique of genomic profiling with surgical extra uterine disease assessment. The investigators aim to correlate EC stage to each of the molecular subgroups of disease and thereby guide surgical treatment and staging of EC by determining the association between molecular classification and disease stage and evaluating if and how disease stage in each of the molecular subgroups associates with prognosis. conditions: Endometrial Cancer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 1000 type: ESTIMATED name: total hysterectomy with bilateral salpingo-oophorectomy, lymph node staging and comprehensive peritoneal staging measure: Endometrial cancer stage measure: Molecular type of endometrial cancer measure: Overall survival measure: Time to recurrence sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: UZ Gasthuisberg, Katholieke Universiteit Leuven status: RECRUITING city: Leuven zip: 3000 country: Belgium name: Ayaka Wakatsuki role: CONTACT phone: +32 16 34 41 69 email: ayaka.wakatsuki@uzleuven.be name: Frédéric Amant, MD, PhD role: PRINCIPAL_INVESTIGATOR lat: 50.87959 lon: 4.70093 hasResults: False
nctId: NCT06354725 id: 2vs4 briefTitle: Effect of Weekly Plyometric Training Frequency on Youth Female Basketball Players: A Comparison of Two vs. Four Sessions overallStatus: COMPLETED date: 2023-11-01 date: 2024-01-20 date: 2024-02-20 date: 2024-04-09 date: 2024-04-09 name: Bruno Figueira class: OTHER name: Vytautas Magnus University briefSummary: Players were randomly assigned to a two-times-a-week (2PLYO, n = 15) or four-times-a-week (4PLYO, n = 15) PT (Plyometric Training) group. Both groups performed the same weekly total volume of jumps during PT in addition to regular basketball training and competition. The 2PLYO group performed 240 jumps over two sessions (120 jumps per session), and the 4PLYO group performed 240 jumps over four sessions (60 jumps per session). After the eight-week intervention, all players underwent a one-week detraining period with no PT training while basketball training and competitions continued. Testing was performed at baseline (pre-test), after intervention (post-test), and after the detraining period. Players were assessed for lower body power using jump tests (countermovement jump \[CMJ\], drop-jump \[DJ\] from a 20-cm box, and horizontal jump \[HJ\]; change of direction ability using a planned agility test; and speed using a 20-m sprint and a 5-m split. conditions: Physical Performance studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: SINGLE whoMasked: INVESTIGATOR count: 30 type: ACTUAL name: Plyometric measure: Horizontal jump measure: CMJ measure: Drop Jump measure: Drop jump (RSI) measure: Linear sprint-5m measure: Linear sprint-20m measure: Change of direction sex: FEMALE minimumAge: 14 Years maximumAge: 16 Years stdAges: CHILD facility: Vytutas Magnus University city: Kaunas country: Lithuania lat: 54.90272 lon: 23.90961 hasResults: False
nctId: NCT06354712 id: 2024-45 briefTitle: Efficacy of N-acetylcysteine in Preventing Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients. overallStatus: RECRUITING date: 2024-04-04 date: 2025-03-01 date: 2025-03-01 date: 2024-04-09 date: 2024-04-09 name: Mansoura University class: OTHER briefSummary: A prospective, randomized, controlled, parallel clinical trial will be conducted at Clinical Oncology and Nuclear Medicine Center at Mansoura University Hospital to assess the efficacy of N-acetylcysteine in the prevention of radiotherapy induced oral mucositis in Head and Neck cancer patients. conditions: Oral Mucositis (Ulcerative) Due to Radiation studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: DOUBLE whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 50 type: ESTIMATED name: N-Acetyl-Cysteine with Institutional standard care name: Institutional standard care measure: Incidence of oral mucositis with grade ≥ 2 assessed weekly by World Health Organization scale for Oral Mucositis. measure: Time to develop oral mucositis with grade ≥ 2. measure: Duration of oral mucositis with grade ≥ 2. measure: Pain assessed by Visual Analog Scale (VAS). measure: Functional oral intake scale measure: Patient's quality of life assessed by Functional Assessment of Cancer Therapy in Head and Neck Cancer (FACT-H&N) version 4 sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Clinical Oncology and Nuclear Medicine of Mansoura University Hospital status: RECRUITING city: Mansoura country: Egypt name: Rasha Abd-Ellatif, Professor role: CONTACT lat: 31.03637 lon: 31.38069 hasResults: False
nctId: NCT06354699 id: RGS0000003993 briefTitle: A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children acronym: POPSICLE overallStatus: RECRUITING date: 2023-06-26 date: 2028-06 date: 2028-07 date: 2024-04-09 date: 2024-04-09 name: Telethon Kids Institute class: OTHER briefSummary: The purpose of this study is to investigate the prevalence, risk factors and consequences of chronic post-surgical pain in children aged 0-16 years through a number of questionnaires completed at various timepoints, from before surgery up to 1 year post surgery. conditions: Chronic Pain studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 5000 type: ESTIMATED measure: The prevalence of chronic post-surgical pain after 10- 12 months. measure: Identifying potential risk factors for chronic post-surgical pain sex: ALL maximumAge: 16 Years stdAges: CHILD facility: Telethon Kids Institute status: RECRUITING city: Perth state: Western Australia country: Australia name: Natalie P Jowett role: CONTACT phone: 08 6456 4809 email: Natalie.Jowett@telethonkids.org.au name: Lliana Slevin role: CONTACT phone: 08 64564806 email: Lliana.slevin@telethonkids.org.au name: Britta von Ungern-Sternberg, Professor role: PRINCIPAL_INVESTIGATOR name: David Sommerfield, Associate role: PRINCIPAL_INVESTIGATOR lat: -31.95224 lon: 115.8614 hasResults: False
nctId: NCT06354686 id: STUDY00004245 briefTitle: Characterizing the Scalp Tolerability of TMS overallStatus: RECRUITING date: 2024-02-12 date: 2026-05 date: 2027-05 date: 2024-04-09 date: 2024-04-09 name: Florida State University class: OTHER briefSummary: The primary objective is to characterize the tolerability of TMS by scalp location (over parietal, motor, modified Beam F3 prefrontal, THREE-D prefrontal, orbitofrontal, and medial prefrontal) and stimulation parameters (single pulse, 10 Hz, theta burst). The secondary objective is to evaluate the knee as a surrogate location to safely trial tolerability of novel TMS parameters. conditions: Healthy studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 40 type: ESTIMATED name: TMS Tolerability measure: Tolerability of TMS - Scalp Location measure: Tolerability of TMS - Stimulation parameters (single pulse, 10 Hz, theta burst). measure: Tolerability of TMS (Knee Location) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Florida State University status: RECRUITING city: Tallahassee state: Florida zip: 32306 country: United States name: Isabelle Taylor, MA role: CONTACT phone: 850-645-8882 email: imtaylor@fsu.edu lat: 30.43826 lon: -84.28073 hasResults: False