hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06333717 id: Dnr 2020-03709 briefTitle: Impact of Whole Grain Rye Bread on Health acronym: FBS overallStatus: COMPLETED date: 2021-03-03 date: 2021-03-03 date: 2021-11-05 date: 2024-03-27 date: 2024-03-27 name: Örebro University, Sweden class: OTHER briefSummary: This randomized controlled trial aims to study how a high intake of a fibre-rich bread affects the composition and functioning of the gut microbiota in healthy subjects, and how this, in turn, impacts on the release of gut peptides, intestinal permeability, stress and cognitive performance. conditions: Healthy Diet studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: DOUBLE maskingDescription: double blinding whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 33 type: ACTUAL name: Whole grain bread name: Control bread measure: Microbiota composition baseline vs after intervention using 16S RNA gene sequencing measure: Microbiota composition whole grain rye bread vs control bread using 16S RNA gene sequencing measure: Concentrations of circulatory short-chain fatty acids SCFA measure: Concentrations of faecal SCFA measure: Concentrations of blood glucagon like peptide-1 (GLP-1) measure: Concentrations of blood glucagon like peptide-2 (GLP-2) measure: Concentrations of blood peptide YY (PYY) measure: Concentrations of blood gastric inhibitory polypeptide (GIP) measure: Concentrations of blood neuroactive peptide Y (NPY) measure: Concentrations of blood brain-derived neurotrophic factor (BDNF) measure: Concentrations of blood cytokines measure: Concentrations of blood alkylresorcinols measure: Concentrations of blood lipopolysaccharide-binding protein (LBP) measure: Concentrations of blood soluble CD-14 (sCD-14) measure: Concentrations of sugars in urine measure: Concentrations of saliva cortisol during stress test measure: Concentrations of saliva alpha-amylase during stress test measure: Gastrointestinal symptoms measured by Gastrointestinal Symptom Rating Scale in Irritable Bowel Syndrome (GSRS-IBS) measure: Food habits measured by an electronic food frequency questionnaire Mealq measure: Food habits measured by a Food diary measure: Physical activity measured by the International Physical Activity Questionnaire (IPAQ) measure: Quality of life measured by the Euro Quality of Life questionnaire measure: Perceived stress measured by a Visual analog scale questionnaire measure: Cognitive control using Eriksen flanker task (Flanker task) measure: Working memory performance using a modified N-back task combined with recent-probes item-recognition task (Sternberg task) measure: Electrocardiogram (ECG) using the Biopac system measure: Electrodermal activity (EDA) using the Biopac system sex: ALL minimumAge: 18 Years maximumAge: 44 Years stdAges: ADULT facility: Örebro University city: Örebro country: Sweden lat: 59.27412 lon: 15.2066 hasResults: False
nctId: NCT06333691 id: Aya Mohammed briefTitle: Comparative Study Between Calcium Gluconate With Diosmin, Cabergoline and Cabergoline With Diosmin overallStatus: COMPLETED date: 2022-10-01 date: 2024-02-01 date: 2024-02-15 date: 2024-03-27 date: 2024-03-27 name: Minia University class: OTHER briefSummary: Ovarian hyperstimulation syndrome is a potentially fatal iatrogenic condition. This syndrome is characterized by a sudden increase of the vascular permeability which results in the development of a massive extravascular exudate in the peritoneal cavity, pleural, pericardium causing ascites, pleural and pericardial effusion.
This syndrome is avoidable by the judicious use of gonadotropins and careful monitoring of stimulation regimens. conditions: Ovarian Hyperstimulation Syndrome studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 180 type: ACTUAL name: Calcium Gluconate measure: the incidence rate of moderate to severe OHSS. sex: FEMALE minimumAge: 23 Years maximumAge: 39 Years stdAges: ADULT facility: Minia University, Faculty of Pharmacy city: Minya country: Egypt lat: 28.10988 lon: 30.7503 hasResults: False
nctId: NCT06333678 id: 22-321 briefTitle: A Study Comparing Sotorasib With Durvalumab in People With Non-Small Cell Lung Cancer (NSCLC) overallStatus: RECRUITING date: 2024-03-20 date: 2027-03 date: 2027-03 date: 2024-03-27 date: 2024-03-27 name: Memorial Sloan Kettering Cancer Center class: OTHER name: Amgen briefSummary: In this study, the researchers will look at whether having participants switch from durvalumab to sotorasib when they have detectable minimal residual disease (MRD) is an effective treatment approach for locally advanced non-small cell lung cancer (LA-NSCLC). The researchers will see whether this switch to sotorasib can control LANSCLC longer compared to the treatment approach of staying on durvalumab (and not switching to sotorasib). conditions: Non-Small Cell Lung Cancer studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Phase II randomized trial primaryPurpose: TREATMENT masking: NONE count: 160 type: ESTIMATED name: Durvalumab name: Sotorasib measure: Progression-free survival (PFS) measure: Incidence of dose-limiting toxicity (DLT) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Memorial Sloan Kettering Basking Ridge (All Protocol Activities) status: RECRUITING city: Basking Ridge state: New Jersey zip: 07920 country: United States name: Narek Shaverdian, MD role: CONTACT phone: 631-212-6323 lat: 40.70621 lon: -74.54932 facility: Memorial Sloan Kettering Monmouth (All Protocol Activities) status: RECRUITING city: Middletown state: New Jersey zip: 07748 country: United States name: Narek Shaverdian, MD role: CONTACT phone: 631-212-6323 lat: 40.39652 lon: -74.09211 facility: Memorial Sloan Kettering Bergen (All Protocol Activities) status: RECRUITING city: Montvale state: New Jersey zip: 07645 country: United States name: Narek Shaverdian, MD role: CONTACT phone: 631-212-6323 lat: 41.04676 lon: -74.02292 facility: Memorial Sloan Kettering Suffolk - Commack (All Protocol Activities) status: RECRUITING city: Commack state: New York zip: 11725 country: United States name: Narek Shaverdian, MD role: CONTACT phone: 631-212-6323 lat: 40.84288 lon: -73.29289 facility: Memorial Sloan Kettering Westchester (All Protocol Activities) status: RECRUITING city: Harrison state: New York zip: 10604 country: United States name: Narek Shaverdian, MD role: CONTACT phone: 631-212-6323 lat: 40.96899 lon: -73.71263 facility: Memorial Sloan Kettering Cancer Center (All Protocol Activities) status: RECRUITING city: New York state: New York zip: 10065 country: United States name: Narek Shaverdian, MD role: CONTACT phone: 631-212-6323 lat: 40.71427 lon: -74.00597 facility: Memorial Sloan Kettering Nassau (All Protocol Activities) status: RECRUITING city: Uniondale state: New York zip: 11553 country: United States name: Narek Shaverdian, MD role: CONTACT phone: 631-212-6323 lat: 40.70038 lon: -73.59291 hasResults: False
nctId: NCT06333665 id: Wei G briefTitle: PPIO-007 Correlation Analysis of Type II Diabetes Mellitus on Short-term and Long-term Outcomes of Patients With Esophageal Squamous Cell Cancer Undergoing Minimally Invasive Esophagectomy overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-20 date: 2024-04-20 date: 2024-05-20 date: 2024-03-27 date: 2024-03-27 name: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University class: OTHER briefSummary: To date, there is controversy as to whether type II diabetes mellitus is associated with adverse short- and long-term outcomes in patients with esophageal squamous cell carcinoma undergoing minimally invasive esophagectomy. At the same time, to the best of our knowledge, the impact of metformin use and glycemic control on short- and long-term outcomes in this patient population is also controversial. Therefore, this study aims to test the hypothesis that diabetes mellitus is associated with reduced survival in patients with esophageal squamous cell carcinoma undergoing minimally invasive esophagectomy and that treatment with metformin and/or good glycemic control (HbA1c\<7.0%) is associated with improved survival. conditions: Esophageal Squamous Cell Carcinoma conditions: Surgery studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 605 type: ACTUAL name: Whether there is type 2 diabetes mellitus before surgery measure: Overall survival measure: Disease-free survival measure: postoperative adverse events measure: perioperative 90-day mortality sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Army Medical Center of the People's Liberation Army city: Chongqing state: Chongqing zip: 400042 country: China lat: 29.56278 lon: 106.55278 hasResults: False
nctId: NCT06333652 id: 22-009239 briefTitle: Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders overallStatus: RECRUITING date: 2024-06-01 date: 2026-12-31 date: 2028-12-31 date: 2024-03-27 date: 2024-04-22 name: Mayo Clinic class: OTHER briefSummary: The researchers are testing a medication named ravulizumab for the treatment of severe preeclampsia and Hemolysis, Elevated Liver enzymes, Low Platelets (HELLP) syndrome. conditions: Preeclampsia studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 14 type: ESTIMATED name: Ravulizumab measure: Alternative Complement Pathway Biomarkers at time of delivery measure: Pregnancy duration measure: Clinical biomarkers of severe features of preeclampsia and HELLP syndrome measure: Hospitalization length in the postpartum period measure: Meningococcal infection after use of ravulizumab sex: FEMALE minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Mayo Clinic Minnesota status: RECRUITING city: Rochester state: Minnesota zip: 55905 country: United States name: Maria L. Gonzalez Suarez, MD,PhD role: CONTACT phone: 507-284-4083 email: gonzalezsuarez.maria@mayo.edu lat: 44.02163 lon: -92.4699 hasResults: False
nctId: NCT06333639 id: 24Chirortho01 briefTitle: Implementing Virtual Reality in the Operating Room acronym: IRVABO overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-10-15 date: 2024-10-15 date: 2024-03-27 date: 2024-03-27 name: Centre Hospitalier Universitaire de Nice class: OTHER briefSummary: "Recently, virtual reality has become more accessible thanks to the use of smaller, more comfortable and easier-to-use devices. Its use in operating theatres is growing.
The visual support offered will be appropriate to the duration of the surgery, i.e. more than 1 hour." conditions: General Surgery conditions: Orthopedic Procedures studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 60 type: ESTIMATED name: orthopaedic surgery name: orthopaedic surgery and fitted with a virtual reality headset measure: To demonstrate the superiority, during long awake orthopaedic surgery, of equipping the patient with a virtual reality headset, on patient satisfaction, compared with the same surgery without a headset. measure: 1. To demonstrate the superiority, during long awake orthopaedic surgery, of equipping the patient with a virtual reality headset, on the doses of premedication, compared with the same surgeries without headset. measure: Evaluate the Virtual Reality device in terms of comfort when wearing the headset, visual comfort and image and scenario quality, and auditory quality sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: CHU NiICE city: Nice state: Alpes Maritimes zip: 0600 country: France name: GAUCI Marc-Olivier role: CONTACT phone: 04 92 03 69 04 phoneExt: +33 email: gauci.mo@chu-nice.fr lat: 43.70313 lon: 7.26608 hasResults: False
nctId: NCT06333626 id: 2020281 briefTitle: Effects of an Oral Multi-vitamin Carbohydrate Beverage on Intraoperative Nausea and Vomiting overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-03-31 date: 2025-03-31 date: 2024-03-27 date: 2024-03-27 name: The First Affiliated Hospital of Soochow University class: OTHER briefSummary: Nausea and vomiting are common and unpleasant symptoms for pregnant women during cesarean section, which can lead to aspiration, a serious complication that can cause pneumonia. Our study aimed to evaluate the effects of oral multi-vitamin carbohydrate beverage on maternal intraoperative nausea and vomiting by gastric ultrasound. conditions: Nausea and Vomiting, Aspiration, Intraoperative studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 90 type: ESTIMATED name: multi-vitamin carbohydrate measure: Gastric antrum area measure: vomiting measure: The pH of vomiting fluid sex: FEMALE minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT hasResults: False
nctId: NCT06333613 id: CR-6565 briefTitle: Evaluation of Acuvue Oasys 1-Day Contact Lenses in New Wearers overallStatus: RECRUITING date: 2024-03-26 date: 2024-05-20 date: 2024-05-20 date: 2024-03-27 date: 2024-04-24 name: Johnson & Johnson Vision Care, Inc. class: INDUSTRY briefSummary: This is a multi-site, bilateral, dispensing, non-randomized, uncontrolled, unmasked, single arm study to evaluate visual acuity in neophytes. conditions: Visual Acuity studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 40 type: ESTIMATED name: ACUVUE OASYS® 1-DAY with HydraLuxe™ TECHNOLOGY (AO1D) measure: Percentage of eyes with slit-lamp findings (Grade 3 or 4) related to study lens wear sex: ALL minimumAge: 13 Years maximumAge: 39 Years stdAges: CHILD stdAges: ADULT facility: Scripps Poway Eyecare & Optometry status: RECRUITING city: San Diego state: California zip: 92131 country: United States lat: 32.71533 lon: -117.15726 facility: Omega Vision Center status: RECRUITING city: Longwood state: Florida zip: 32779 country: United States lat: 28.70305 lon: -81.3384 facility: Maitland Vision Center - North Orlando Ave status: RECRUITING city: Maitland state: Florida zip: 32751 country: United States lat: 28.62778 lon: -81.36312 facility: Kannarr Eye Care status: RECRUITING city: Pittsburg state: Kansas zip: 66762 country: United States lat: 37.41088 lon: -94.70496 facility: Procare Vision Centers status: RECRUITING city: Granville state: Ohio zip: 43023 country: United States lat: 40.06812 lon: -82.5196 hasResults: False
nctId: NCT06333600 id: Soh-Med-23-07-05 briefTitle: Efficacy and Safety of Topical Vitamin D Analogue in Treatment of Female Pattern Hair Loss overallStatus: RECRUITING date: 2023-05-20 date: 2024-04-01 date: 2024-05-01 date: 2024-03-27 date: 2024-03-27 name: Sohag University class: OTHER briefSummary: The trial aims to study efficay of topical vitamin D analogue in treatment of female pattern hair loss cases conditions: Dermatology conditions: Female Pattern Baldness studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 45 type: ESTIMATED name: Topical minoxidil name: Topical Vitamin D name: Saline spray measure: Change of Sinclaire grading of Female pattern hair loss measure: Change of Trichoscopic parameters (Hair dermoscopy) sex: FEMALE minimumAge: 15 Years maximumAge: 60 Years stdAges: CHILD stdAges: ADULT facility: Facult of Medicine, Sohag Uniiversity status: RECRUITING city: Sohag zip: 82515 country: Egypt name: Doaa G Abdelbaset, MSc role: CONTACT phone: 01022330810 phoneExt: 002 email: dodygaber64@yahoo.com name: Doaa G Abdelbaset, Msc role: CONTACT phone: 01014733007 phoneExt: 002 email: dodygaber64@yahoo.com lat: 26.55695 lon: 31.69478 hasResults: False
nctId: NCT06333587 id: IEO 1810 briefTitle: Minimally Invasive Treatments of the Thyroid acronym: MIPA-MITT overallStatus: RECRUITING date: 2022-10-10 date: 2025-12-31 date: 2035-12-31 date: 2024-03-27 date: 2024-03-27 name: European Institute of Oncology class: OTHER briefSummary: This is a prospective cohort study to test Minimally Invasive Treatments of the Thyroid (MITT) as potential alternative to surgery in patients with Papillary Thyroid MicroCarcinoma (PTMC) conditions: Papillary Thyroid Microcarcinoma studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 270 type: ESTIMATED name: image-guided thermal ablation measure: The proportion of patients with major complications occurring within one month after the date of intervention measure: Percentage of patients with local recurrence at 10 years measure: Percentage of patients with distant metastasis at 10 years measure: Percentage of patients died at 10 years sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: European Institute of Oncology status: RECRUITING city: Milan country: Italy name: Giovanni Mauri role: CONTACT lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06333574 id: CDUTCM20240313 briefTitle: Weight Management of Dialysis Patients overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-12-31 date: 2024-12-31 date: 2024-03-27 date: 2024-03-27 name: qinxiu zhang class: OTHER briefSummary: The goal of this clinical trial is to Improve the quality of life in Hemodialysis patient. The main questions it aims to answer are:
Intervention group: On the basis of routine outpatient management, patients or their family members were subjected to remote follow-up management based on wechat, and the follow-up time was 6 months. Specific methods: Same as the control group, the information of weight and blood pressure of the patients was registered at the end of dialysis, and the purpose, role and importance of weight management were informed to the patients. On this basis, a special wechat signal is set up to add patients or patients\' family members as wechat friends and establish a wechat interaction platform with patients. In the interdialysis period, remind patients to weigh themselves through wechat (the time of each weighing is fixed, preferably consistent with the time of weighing in the hemodialysis center), control the weight gain during the interdialysis period not to exceed 4.5% of dry weight, and inform patients again about the purpose, role and importance of weight management. conditions: Hemodialysis conditions: Life Quality conditions: Interdialytic Weight Gain conditions: Cardiovascular Events conditions: Hypertension conditions: Dry Weight studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 100 type: ESTIMATED name: Family weight self-measurement and remote follow-up management based on wechat. name: Routine care measure: Adverse event rate measure: Rate of completion measure: dialysis related symptoms measure: Laboratory index measure: level of Ga measure: level of P measure: level of PTH measure: level of K measure: level of Na measure: level of Cl measure: concentration of albumin and prealbumin measure: Laboratory index of total protein measure: Dialysis efficiency \ dialysis adequacy (KTV) sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06333561 id: Liver Project 7 briefTitle: HAIC Combined With Lenvatinib and PD-1 Inhibitor in Infiltrative Hepatocellular Carcinoma overallStatus: RECRUITING date: 2021-01-01 date: 2024-12-30 date: 2024-12-30 date: 2024-03-27 date: 2024-03-27 name: Sun Yat-sen University class: OTHER briefSummary: Hepatic arterial infusion chemotherapy (HAIC) plus lenvatinib and programmed cell death protein-1 (PD-1) inhibitor have shown promising results for advanced hepatocellular carcinoma (HCC). However, the evidence for infiltrative is limited. In this study, we aimed to describe the efficacy and safety of lenvatinib and PD-1 inhibitor with HAIC plus lenvatinib for infiltrative HCC. conditions: Hepatocellular Carcinoma conditions: Lenvatinib conditions: PD-1 Inhibitor conditions: Hepatic Arterial Infusion Chemotherapy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 300 type: ESTIMATED name: Hepatic arterial infusion chemotherapy name: Lenvatinib name: Tislelizumab name: Toripalimab name: Sintilimab name: Camrelizumab measure: Overall survival measure: Progression-Free-Survival measure: Objective response rate sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Chinese PLA General hospital status: RECRUITING city: Beijing state: Beijing zip: 100853 country: China name: Qunfang Zhou, Md role: CONTACT phone: 8619868000115 email: zhouqun988509@163.com name: Feng Duan, MD role: CONTACT phone: 8613910984586 email: duanfeng@vip.sina.com lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06333548 id: KSH_MB_2024_1 briefTitle: Cord Blood Alarin Levels in Term Babies overallStatus: COMPLETED date: 2023-09-18 date: 2023-12-23 date: 2024-01-15 date: 2024-03-27 date: 2024-03-29 name: Konya City Hospital class: OTHER briefSummary: In this study, alarin levels in the cord blood of babies with large birth weights will be compared with babies of normal weight. Thus, the investigators aimed to find out whether there is a relationship between babies' birth weights and alarin. conditions: Birth Weight studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 87 type: ACTUAL name: Appropriate for gestational age , small for gestational age, large for gestational age, Baby of mother diagnosed with GDM measure: Comparison of cord blood alarin levels of babies in different groups according to birth weight (low-appropriate-large) and babies of mothers diagnosed with gestational diabetes regardless of birth weight. sex: ALL minimumAge: 1 Minute maximumAge: 5 Minutes stdAges: CHILD facility: MELEK city: Konya state: Sıhhiye zip: 06100 country: Turkey lat: 37.87135 lon: 32.48464 hasResults: False
nctId: NCT06333535 id: 2022/568 briefTitle: Foot and Abdominal Massage Applied to After Colonoscopy overallStatus: COMPLETED date: 2023-06-01 date: 2024-01-01 date: 2024-02-25 date: 2024-03-27 date: 2024-03-27 name: TC Erciyes University class: OTHER briefSummary: The aim of this study was to determine the effect of foot and abdominal massage applied to after colonoscopy on abdominal distention, pain and patient satisfaction.This was a randomized controlled experimental study conducted at the Colonoscopy unit in Medica Faculty Hospital . Participants assigned to the intervention group-1 received foot massages after colonoscopy, participants assigned to the intervention group-2 received abdominal massages after colonoscopy and participants assigned to the intervention group-3 received foot and abdominal massages after colonoscopy. Participants assigned to the control group received only "routine care" after colonoscopy. The abdominal pain, distension and satisfaction levels of the patients evaluated using the Numerical Rating Scale conditions: Abdominal Pain conditions: Distention conditions: Satisfaction, Patient studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 96 type: ACTUAL name: foot massage name: abdominal massage name: foot and abdominal massage measure: abdominal pain measure: Abdominal distension measure: Patient Satisfaction sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Erciyes University city: Kayseri zip: 38000 country: Turkey lat: 38.73222 lon: 35.48528 hasResults: False