hackint0sh/New-Dataset huggingface dataset:
In SEIFEM 2016 study the investigators demonstrated that the incidence of IA during the AML consolidation is low. However, the mortality is not negligible, mainly in older patients. Further, a sub-analysis in the subset of patients older than 60 years demonstrated that patients who didn't receive mold active prophylaxis had higher incidence of IA than patients who received mold active prophylaxis (15% vs 6%). Therefore, as prophylaxis seems to prevent IA in consolidation, further studies should be performed especially in elderly patients treated with HDAC to confirm our data and to identify the subset of patients who require PAP. conditions: Invasive Aspergillosis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 300 type: ESTIMATED measure: the incidence of proven, probable and possible IA in patients enrolled in the study in both groups of patients measure: overall mortality rate sex: ALL minimumAge: 60 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Tor Vergata University status: RECRUITING city: Roma state: RM zip: 00133 country: Italy name: Maria Ilaria Del Principe role: CONTACT phone: 3394080659 email: del.principe@med.uniroma2.it lat: 41.89193 lon: 12.51133 hasResults: False
nctId: NCT06382909 id: 202302 briefTitle: Effect of Probiotic Compound K11T e K11TMax in ASD acronym: ASD overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-22 date: 2024-07-07 date: 2025-04-07 date: 2024-04-24 date: 2024-04-29 name: Deivis de Oliveira guimaraes class: NETWORK name: SENAI CIMATEC briefSummary: The research is characterized as a randomized, double-blind clinical trial (phase III) in which administered the probiotic K11-T (with and without added amino acids, fatty acids and vitamins) to children between 3 and 11 years old with Autism Spectrum Disorder - ASD, being subsequently assessed outcomes related to inflammatory markers and neuropsychiatric and sociopedagogical criteria. To this end, the study will create three groups, one of which will be a control group, which will receive a placebo, the other will receive the probiotic without micronutrients and another will receive the probiotic with added nutrients. conditions: Autism Spectrum Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Double blind, randomized, with placebo control primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 505 type: ACTUAL name: Inflammatory level name: Cognitive assessment name: Pedagogical assessment measure: Inflammation biomarker 1 measure: Inflammation biomarker 2 measure: Inflammation biomarker 3 measure: Inflammation biomarker 4 measure: Inflammation biomarker 5 measure: Neuropsychological Assessment measure: Psychiatric Assessment measure: Psychopedagogical Assessment measure: Comparative of outcomes between arm that took K11-T and arm that took K11-Tmax. sex: ALL minimumAge: 3 Years maximumAge: 11 Years stdAges: CHILD facility: Gon1 P&D city: Vitoria state: ES zip: 29050335 country: Brazil lat: -20.31944 lon: -40.33778 facility: Gon1 gestora de Projetos city: Vitória state: ES zip: 29050335 country: Brazil lat: -20.31944 lon: -40.33778 typeAbbrev: Prot hasProtocol: True hasSap: False hasIcf: False label: Study Protocol date: 2024-03-22 uploadDate: 2024-04-18T21:12 filename: Prot_000.pdf size: 369916 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2024-03-22 uploadDate: 2024-04-16T10:55 filename: ICF_001.pdf size: 192688 hasResults: False
nctId: NCT06382896 id: FirstAHXiamenU-YB-2 briefTitle: Effect of Oliceridine on Rebound Pain overallStatus: RECRUITING date: 2024-01-01 date: 2025-12-31 date: 2025-12-31 date: 2024-04-24 date: 2024-04-25 name: The First Affiliated Hospital of Xiamen University class: OTHER briefSummary: The purpose of this clinical study was to identify the risk factors for postoperative pain outburst in patients undergoing arthroscopic knee surgery after Oliceridine and nerve block, and to evaluate the effect of oxeridine on early rehabilitation exercise in patients. A total of 320 patients undergoing arthroscopic knee arthroscopy under general anesthesia combined with femoral nerve block were selected to record the time and duration of postoperative pain outbreak, pain degree, age, gender, operation type, previous surgical history and other related risk factors. conditions: Rebound Pain conditions: Arthroscopic Knee Surgery conditions: Oliceridine studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 320 type: ESTIMATED name: No intervention measure: Time of onset of postoperative rebound pain measure: The duration of the rebound pain measure: The degree of the rebound pain measure: age measure: sex measure: Surgical procedure measure: Previous surgical history measure: Movement recovery time sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: First Affiliated Hospital of Xiamen University status: RECRUITING city: Xiamen state: Fujian zip: 361000 country: China name: Bin Yang, doctor role: CONTACT phone: 13859986036 email: yangbin4332@outlook.com lat: 24.47979 lon: 118.08187 hasResults: False
nctId: NCT06382883 id: FINELO2024 briefTitle: Lifestyle and Physical Activity as Part Of Obstructive Sleep Apnea Treatment acronym: ELO overallStatus: RECRUITING date: 2024-04-22 date: 2026-07-31 date: 2026-07-31 date: 2024-04-24 date: 2024-04-24 name: Filha ry class: OTHER name: University of Jyvaskyla name: Organisation for Respiratory Health in Finland name: Central Finland Hospital District briefSummary: The goal of this clinical trial is to investigate the effects of an individually tailored lifestyle intervention on symptoms and severity of obstructive sleep apnea (OSA), physical activity (PA) levels and sedentary behavior (SB), as well as health and wellbeing in overweight participants with moderate to severe OSA treated with CPAP. Emphasis of the individually tailored SEMC-intervention (protocol of the Sports Medicine Outpatient Clinic of The Wellbeing Services County of Central Finland) is on increasing the amount of total physical activity.
In this study, it is hypothesized that participants receiving SEMC-intervention in combination with CPAP therapy will experience greater alleviation of OSA severity and symptoms, improve their quality of life, body composition and physical functioning, as well as increase physical activity levels and decrease their sedentary behavior compared to the control group. In addition, it is hypothesized that participants receiving SEMC-intervention and EBS in combination with CPAP therapy will increase their physical activity levels, and decrease their sedentary behavior to a greater extent, and these changes will be more sustained compared to merely SEMC-intervention or control group. conditions: Obstructive Sleep Apnea studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 300 type: ESTIMATED name: Individually tailored lifestyle and physical activity intervention name: Individually tailored lifestyle and physical activity intervention combined with enhanced behavioral support -intervention (EBS) measure: Change in apnea-hypopnea-index (AHI) measure: Change on sleep apnea symptoms measure: Change in the mean daily total light physical activity time measure: Change in the mean daily total moderate to vigorous (MVPA) physical activity time measure: Change in the mean daily total sedentary time measure: Change in 6-minute walk distance (6MWD) in meters measure: Change in hand grip strength in kilograms measure: Change in waist circumference in centimeters measure: Change in body weight in kilograms measure: Change in visceral fat area (VFA) in square centimeters measure: Change in muscle mass in kilograms measure: Change in Quality of Life RAND 36-Item Health Survey sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Central Finland Hospital District status: RECRUITING city: Jyväskylä zip: 40620 country: Finland name: Merja Perhonen role: CONTACT email: merja.perhonen@hyvaks.fi name: Antti Saarinen role: CONTACT email: antti.saarinen@filha.fi lat: 62.24147 lon: 25.72088 hasResults: False
nctId: NCT06382870 id: 107.2023fbu briefTitle: Simulation-Based Training for Child Neglect and Abuse overallStatus: NOT_YET_RECRUITING date: 2024-05-29 date: 2024-06-15 date: 2024-06-29 date: 2024-04-24 date: 2024-04-24 name: Fenerbahce University class: OTHER briefSummary: Child abuse and neglect is a broad structure that includes physical abuse, sexual abuse, emotional abuse and neglect. Child neglect and abuse is one of the primary areas of responsibility of health professionals, which negatively affects child health and threatens public health in the long term. All healthcare professionals are legally obligated to report known or suspected cases of child abuse and neglect. Health professionals, in particular, play an important role in stopping child abuse by assessing children, identifying risk factors, and reporting suspected child maltreatment to authorities. Early diagnosis of a neglected and abused child is important in reducing the recurrence of maltreatment.
Regarding the evaluation of child neglect and abuse, healthcare professionals should approach a child who presents with suspicious injuries, thinking that he or she may be abused. The key here is to be aware of the problem. Health professionals should carefully examine children and fulfill their responsibilities by identifying possible clues to abuse and neglect. It is recommended that clues to recognize neglect and abuse be taught within the scope of in-service training for healthcare professionals working in hospitals. conditions: Simulation-based Training studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 24 type: ESTIMATED name: education measure: The awareness level sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06382857 id: 823779-MDF Niger briefTitle: Effectiveness of a Microbiome-directed Food to Promote Programmatic and Sustained Nutritional Recovery Among Children With Uncomplicated Acute Malnutrition overallStatus: RECRUITING date: 2024-05-02 date: 2025-11-01 date: 2026-02-01 date: 2024-04-24 date: 2024-04-29 name: Epicentre class: OTHER name: Epicentre, Niger name: National Nutrition Direction, Niger name: Ministry of Public Health and Social Affairs, Niger name: Regional Direction of Public Health, Maradi briefSummary: This study is an individually randomized controlled trial comparing microbiome-directed foods to standard nutritional therapy among children aged 6 to \< 24 months with uncomplicated acute malnutrition in terms of programmatic recovery by 12 weeks from admission and sustained recovery at 24 weeks from admission. conditions: Malnutrition, Child studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 7356 type: ESTIMATED name: MDF name: RUTF name: RUSF measure: Programmatic recovery by 12 weeks from admission measure: Sustained recovery at 24 weeks from admission measure: Default measure: Non-response measure: Time to recovery measure: For MAM children: Deterioration to SAM measure: Change in weight gain measure: Change in weight-for-length Z (WLZ) measure: Change in length-for-age Z (LAZ) measure: Change in weight-for-age Z (WAZ) measure: Change in MUAC measure: Serious adverse events measure: Hospitalization measure: Death measure: Motor, cognitive, language, social-emotional, and mental health skills measure: Cost effectiveness measure: Dietary intake measure: Adherence measure: Microbiome profile at enrollment, week 4, program discharge, and study discharge measure: Plasma proteome profile at enrollment, week 4, program discharge, and study discharge measure: Environmental enteric dysfunction at enrollment, program discharge, and study discharge measure: Change of fat mass and fat-free mass at program discharge and study discharge measure: Micronutrient status at enrollment, program discharge and study discharge measure: Immuno-sufficiency at week 2, week 4, program discharge, week 12 and study discharge (SAM only) sex: ALL minimumAge: 6 Months maximumAge: 23 Months stdAges: CHILD facility: Epicentre Niger status: RECRUITING city: Maradi country: Niger name: Ousmane Guindo, MD role: CONTACT email: ousmane.guindo@epicentre.msf.org name: Ibrahim Ngoumboute, MD role: CONTACT email: ibrahim.ngoumboute@epicentre.msf.org lat: 13.5 lon: 7.10174 hasResults: False
nctId: NCT06382831 id: IndonesiaU240201 briefTitle: Opioid Free Versus Opioid Balanced Anesthesia in Ophthalmic Surgery overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2024-08-01 date: 2024-10-01 date: 2024-04-24 date: 2024-04-24 name: Indonesia University class: OTHER briefSummary: Anesthesia without the use of opioid (Opioid free anesthesia) is an alternative to conventional opioid balanced anesthesia, with less post operative nausea and vomiting, and comparable analgesia. This study aim to compare the effect of opioid free versus opioid balanced anesthesia in ophthalmology surgery conditions: Anesthesia and Analgesia conditions: Anesthesia, Endotracheal studyType: INTERVENTIONAL phases: PHASE2 phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 104 type: ESTIMATED name: Dexmedetomidine name: Fentanyl measure: Postoperative nausea and vomiting (PONV) measure: Pain score measure: Time to laryngeal mask exertion measure: Adverse effect sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06382818 id: PROICM 2023-10 PRO briefTitle: Personalization of Breast Radiotherapy According to Loco-regional Recurrence Risk and Toxicity Probability acronym: PROBA overallStatus: NOT_YET_RECRUITING date: 2024-04-26 date: 2027-04-26 date: 2036-04-26 date: 2024-04-24 date: 2024-04-24 name: Institut du Cancer de Montpellier - Val d'Aurelle class: OTHER briefSummary: Our objective is based on a personalized approach of adjuvant breast radiotherapy by selecting patients according to tumor recurrence and toxicity risk. conditions: Breast Cancer studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: * COHORT A = Low risk of recurrence / Low risk of breast toxicity
* COHORT D = High risk of recurrence / High risk of breast toxicity primaryPurpose: TREATMENT masking: NONE count: 854 type: ESTIMATED name: COHORT A name: COHORT B name: COHORT C name: COHORT D measure: Rate of patients without any grade 2 or more fibrosis, nor radio-induced sarcoma measure: Acute toxicity measure: Late toxicity measure: Local recurrence rate (LRR) measure: Relapse-free survival (RFS) rate measure: Overall survival (OS) rate measure: Radiation-induced Breast Sarcoma prevalence sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Institut Du Cancer de Montpellier city: Montpellier country: France name: MOUSSION AURORE role: CONTACT phone: 0467613102 email: aurore.moussion@icm.unicancer.fr name: AZRIA DAVID role: PRINCIPAL_INVESTIGATOR name: MEGE ALICE role: PRINCIPAL_INVESTIGATOR name: BRETON-CALLU CHRISTEL role: PRINCIPAL_INVESTIGATOR lat: 43.61092 lon: 3.87723 hasResults: False
nctId: NCT06382805 id: HasanKU_FTR_AA_02 briefTitle: Comparison of the Effects of Kinesio Tape and High-intensity Laser Therapy in Lateral Epicondylitis overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-10-01 date: 2024-11-15 date: 2024-04-24 date: 2024-04-25 name: Hasan Kalyoncu University class: OTHER briefSummary: Lateral epicondylitis is a common upper extremity disease that occurs with tenderness in the lateral epicondyle, the common attachment point of the wrist extensor muscles, and pain during resisted wrist extension. The main purpose of treating lateral epicondylitis is to reduce pain and increase functionality, but there is no accepted standard treatment method. The purpose of this study is to compare the effectiveness of kinesio tape and high intensity laser in the treatment of lateral epicondylitis. conditions: Tennis Elbow conditions: Physical Therapy conditions: Kinesiotaping conditions: Laser studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: There are three groups in the study. The groups consist of the control group, kinesio tape group and high intensity laser group primaryPurpose: TREATMENT masking: NONE count: 45 type: ESTIMATED name: Physiotherapy program name: Kinesio Tape name: High Intensity Laser therapy measure: Pain Measurement measure: Hand grip strength measure: Patient-Rated Tennis Elbow Evaluation measure: Pain Sensitivity Measurement sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Hasan Kalyoncu University city: Gaziantep zip: 27000 country: Turkey lat: 37.05944 lon: 37.3825 hasResults: False
nctId: NCT06382792 id: 2024PI059 briefTitle: Osteolysis of Allograft Prosthetic Composite After Shoulder Resection for Tumors overallStatus: ENROLLING_BY_INVITATION date: 2024-05-01 date: 2024-05-01 date: 2024-05-01 date: 2024-04-24 date: 2024-04-24 name: Central Hospital, Nancy, France class: OTHER briefSummary: The gold standard after shoulder resection for tumors is reconstruction by reverse prosthesis and allograft. This is an intervention also performed for more frequent etiologies (revisions of prosthesis, non cancerous humeral bone loss ...).
The results in these etiologies are good, and do not find any particular mechanical complications (including no osteolysis of the graft). In the case of reconstruction for cancer, the numbers of patients are lower (rare pathologies) and some studies on small numbers found osteolysis of the allograft. The aim of this study is to analyze the presence or not osteolysis in these patients, and to quantify it precisely by scanner measurement (no data yet in the literature). conditions: Shoulder Disease studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 6 type: ESTIMATED name: proximal humeral resection for tumor and allograft prosthetic composite reconstruction measure: Osteolysis (bone stock in cm3) measure: Constant score measure: Complications measure: Revision sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Central Hopital city: Nancy zip: 54000 country: France lat: 48.68439 lon: 6.18496 hasResults: False
nctId: NCT06382779 id: 2024PI057 briefTitle: Proximal Humerus Reconstruction After Resection for Tumors : Comparison Between Allograft Prosthetic Composite and Cement Sleeve Prosthetic Composite overallStatus: ENROLLING_BY_INVITATION date: 2024-04-15 date: 2024-05-01 date: 2024-05-01 date: 2024-04-24 date: 2024-04-24 name: Central Hospital, Nancy, France class: OTHER briefSummary: Proximal humerus is a common site for primary bone tumors and metastatic disease. Reconstruction with reverse shoulder arthroplasty (RSA) after resection is a surgical challenge and presented high risk of complication. The options for reconstruction after proximal humerus tumor resection are limited, and depend on the soft tissue conditions and bone loss. The most commonly used techniques include long cemented stem alone (in case of limited resection), allograft prosthetic composite (APC), massive prosthesis. In some cases two step procedure are performed : first step is resection and RSA with cement sleeve, and second step is APC or massive prosthesis. conditions: Shoulder Disease studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: RETROSPECTIVE count: 32 type: ESTIMATED name: reverse shoulder arthroplasty measure: Constant score measure: complication measure: mortality measure: revision sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: CHRU - Centre chirurgical emile galle city: Nancy zip: 54000 country: France lat: 48.68439 lon: 6.18496 hasResults: False
nctId: NCT06382766 id: SMU in malnutrition briefTitle: Skeletal Muscle Ultrasonography in Detection of Malnutrition overallStatus: NOT_YET_RECRUITING date: 2025-03 date: 2026-03 date: 2026-03 date: 2024-04-24 date: 2024-04-24 name: Assiut University class: OTHER briefSummary: * To detect the role of Skeletal Muscle Ultrasonography in Detection of Malnutrition and Prediction of The Outcome among critically ill children.
* To assess the accuracy and validity of muscle ultrasonography in assessment of the nutritional status of critically ill child compared with other different nutritional assessment tools . conditions: Skeletal Muscle Ultrasonography studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 50 type: ESTIMATED name: Skeletal Muscle Ultrasonography measure: accuracy of Skeletal Muscle Ultrasonography in Detection of Malnutrition and Prediction of The Outcome among critically ill children comared with other traditional nutritional assessment tools . sex: ALL minimumAge: 1 Month maximumAge: 5 Years stdAges: CHILD hasResults: False
nctId: NCT06382753 id: 20-24-PAR briefTitle: Impact of Periodontal Supportive Therapy in Patients With Gingivitis and Periodontitis overallStatus: RECRUITING date: 2024-04-20 date: 2024-06-30 date: 2024-06-30 date: 2024-04-24 date: 2024-04-24 name: University of Catania class: OTHER briefSummary: The study evaluated the number of sessions of periodontal supportive treatment in patients with gingivitis in order to evaluate the risk of periodontitis development. conditions: Gingivitis conditions: Periodontitis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 150 type: ESTIMATED name: Gingival inflammation measure: Bleeding on Probing sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: AOU Policlinico G. Rodolico status: RECRUITING city: Catania zip: 95124 country: Italy name: Gaetano Isola, DDS role: CONTACT phone: 0953785652 email: gaetano.isola@unict.it lat: 37.49223 lon: 15.07041 hasResults: False
nctId: NCT06382740 id: AOP2097 briefTitle: Selection Protocol for Liver Transplantation in Patients Aged Over 70 Years acronym: Over70-LT overallStatus: RECRUITING date: 2022-10-01 date: 2025-10-01 date: 2025-10-01 date: 2024-04-24 date: 2024-04-24 name: Azienda Ospedaliera di Padova class: OTHER briefSummary: Increased life expectancy and aging population has led to a trend of increasing liver transplant (LT) volume in the elderly. Nowadays, advanced age is not considered an absolute contraindication for LT but elderly LT candidates typically have an age-associated burden of comorbid conditions that can pose several clinical challenges during the selection/evaluation process for LT. Specific algorithms for elderly patient selection for LT are not well established; however, consensus agreement is that elderly LT candidates need a more rigorous selection process.
This study proposes a "step by step" algorithm of selection for liver transplant candidates more than 70 years. conditions: End Stage Liver DIsease conditions: Liver Transplantation conditions: Old Age studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 18 type: ESTIMATED name: Liver transplantation measure: 1 year patient survival measure: 1 year graft survival measure: 3 months mortality and morbidity sex: ALL minimumAge: 71 Years maximumAge: 75 Years stdAges: OLDER_ADULT facility: U.O.C Chirurgia Epatobiliare e Trapianti Epatici, Azienda Ospedaliera di Padova status: RECRUITING city: Padova zip: 35128 country: Italy name: Umberto Cillo, MD role: CONTACT email: cillo@unipd.it lat: 45.40797 lon: 11.88586 hasResults: False