hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06360614 id: 2024s01 briefTitle: The Effect of Hand Massage Applied to Palliative Care Oncology Patients overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-01 date: 2025-06-01 date: 2024-04-11 date: 2024-04-15 name: murat koç class: OTHER_GOV name: Istanbul Sultanbeyli State Hospital briefSummary: World Health Organization (WHO) palliative care is defined as "an approach that aims to reduce or prevent suffering by early identification, evaluation and treatment of the physical, psychosocial and spiritual problems of patients and families accompanying life-threatening diseases, and thus to increase their quality of life." Palliative care is a multidisciplinary approach that provides appropriate health care for oncology patients, who have a wide variety of medical, functional, social and emotional needs. Pharmacological approaches are generally used in symptom management of palliative care patients. In addition to pharmacological approaches, non-pharmacological approaches are also preferred. Massage is a preferred intervention among professional nursing practices because it is reliable, has no side effects, has a direct effect on patients, and is easy to apply.
Massage is the stimulation of the skin, subcutaneous tissue, muscles, internal organs, metabolism, circulation and lymph systems for therapeutic purposes through mechanical and neural means. The presence of sufficient mechanoreceptors in the hands, which stimulate painless nerve endings, shows that the hands should be chosen as the appropriate area for massage. Among the effects of hand massage: ensuring the regeneration of cells, facilitating the elimination of accumulated toxins, providing relaxation, helping to reduce pain by facilitating the release of endorphins, helping to increase circulation, regulating respiratory functions, providing stress and anxiety control, creating a state of well-being, strengthening the immune system, increasing general comfort, improving sleep quality. is located. Studies in the literature have found that hand massage reduces anxiety levels, stress and agitation levels, pain levels, and increases comfort and sleep levels. As seen in the literature, the effectiveness of hand massage applied to different sample groups on anxiety, stress, agitation, pain, comfort and sleep parameters was evaluated. There are very few studies evaluating the effectiveness of hand massage applied to oncology patients. In addition, no study has been found that evaluated the effects of hand massage on pain, comfort and sleep in palliative oncology patients, who constitute the majority of palliative care patients. conditions: Hand Massage studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Before the application, data will be collected and recorded through a face-to-face interview (8-10 minutes) by a nurse who does not know which group the patients are in. Sleep times of patients will be measured with a smart bracelet. At this stage, the same procedure will be continued for the intervention and control groups.
In the intervention and control groups, VAS-Pain, General Comfort Scale and Pittsburgh Sleep Quality were assessed by a face-to-face interview by a nurse who did not know which group the patients were in, on the 7th day (Monday), 14th day (Monday) and 28th day (Monday). Index measurement tools will be applied and patients' sleep times will be measured with a smart bracelet. primaryPurpose: SCREENING masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 80 type: ESTIMATED name: Hand massage application name: routine monitoring and nursing care measure: İndividual Information Form measure: Patient Follow-up Form measure: General Comfort Scale measure: Pittsburgh Sleep Quality Index measure: Smart Bracelet sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sultanbeyli State Hospital city: Istanbul zip: 34000 country: Turkey name: Murat Koç role: CONTACT phone: +905436725093 email: mrtkoc49@gmail.com lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06360601 id: 36264PR589/3/24 briefTitle: Intravenous Labetalol Versus Hydralazine in Preeclampsia overallStatus: ACTIVE_NOT_RECRUITING date: 2024-04-01 date: 2024-09 date: 2024-09 date: 2024-04-11 date: 2024-04-11 name: Tanta University class: OTHER briefSummary: We study the effect of intravenous labetalol versus hydralazine in sever preeclampsia patients on cerebral blood flow and neurological outcome conditions: Preeclampsia Severe studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: Labetalol Injection name: HydrALAZINE Injection measure: Cerebral blood flow sex: FEMALE minimumAge: 25 Years maximumAge: 45 Years stdAges: ADULT facility: Faculty of Medicine city: Tanta zip: 3511 country: Egypt lat: 30.78847 lon: 31.00192 hasResults: False
nctId: NCT06360588 id: NCI-2024-01141 id: NCI-2024-01141 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: EAY131-Z1G type: OTHER domain: ECOG-ACRIN Cancer Research Group id: EAY131-Z1G type: OTHER domain: CTEP id: U10CA180820 type: NIH link: https://reporter.nih.gov/quickSearch/U10CA180820 briefTitle: Testing Copanlisib as Potentially Targeting Treatment in Cancers With PTEN Loss (MATCH - Subprotocol Z1G) overallStatus: ACTIVE_NOT_RECRUITING date: 2018-06-19 date: 2024-11-15 date: 2024-11-15 date: 2024-04-11 date: 2024-04-22 name: National Cancer Institute (NCI) class: NIH briefSummary: The phase II MATCH treatment trial tests how well copanlisib works to treat patients with cancer with PTEN loss. Copanlisib may stop the growth of tumor cells and may kill them by blocking some of the enzymes needed for cell growth. conditions: Malignant Solid Neoplasm studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 35 type: ESTIMATED name: Biopsy name: Biospecimen Collection name: Copanlisib name: Radiologic Examination measure: Objective response rate (ORR) measure: Overall survival (OS) measure: 6-month progression-free survival (PFS) rate measure: Progression free survival sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: ECOG-ACRIN Cancer Research Group city: Philadelphia state: Pennsylvania zip: 19103 country: United States lat: 39.95233 lon: -75.16379 hasResults: False
nctId: NCT06360575 id: NCI-2024-01127 id: NCI-2024-01127 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: EAY131-C2 type: OTHER domain: ECOG-ACRIN Cancer Research Group id: EAY131-C2 type: OTHER domain: CTEP id: U10CA180820 type: NIH link: https://reporter.nih.gov/quickSearch/U10CA180820 briefTitle: Testing Crizotinib as Potentially Targeted Treatment in Cancers With MET Exon 14 Deletion Genetic Changes (MATCH - Subprotocol C2) overallStatus: ACTIVE_NOT_RECRUITING date: 2016-05-30 date: 2024-11-15 date: 2024-11-15 date: 2024-04-11 date: 2024-04-22 name: National Cancer Institute (NCI) class: NIH briefSummary: This phase II MATCH treatment trial tests how well crizotinib works to treat patients with cancers with MET exon 14 deletion genetic changes. Crizotinib is in a group of medications called tyrosine kinase inhibitors. It works by blocking enzymes that cancer cells need to grow and spread. It may also prevent the growth of new blood vessels that tumors need to grow. conditions: Advanced Lymphoma conditions: Advanced Malignant Solid Neoplasm conditions: Refractory Lymphoma conditions: Refractory Malignant Solid Neoplasm conditions: Refractory Multiple Myeloma studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 35 type: ESTIMATED name: Biopsy name: Biospecimen Collection name: Crizotinib name: Radiologic Examination measure: Objective response rate (ORR) measure: Overall survival (OS) measure: 6-month progression-free survival (PFS) rate measure: Progression free survival sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: ECOG-ACRIN Cancer Research Group city: Philadelphia state: Pennsylvania zip: 19103 country: United States lat: 39.95233 lon: -75.16379 hasResults: False
nctId: NCT06360562 id: 2020P002418 briefTitle: Reconnecting to Ourselves and Others in Virtual Meetings (ROOM) overallStatus: RECRUITING date: 2020-09-15 date: 2025-01-30 date: 2025-04-25 date: 2024-04-11 date: 2024-04-11 name: Massachusetts General Hospital class: OTHER briefSummary: This study aimed to determine the feasibility and acceptability of delivering Resilience Training in multi-user virtual reality. conditions: Mood Disorders conditions: Anxiety Disorders conditions: Psychotic Disorders studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 174 type: ESTIMATED name: Resilience Training measure: Discomfort with Others measure: Intervention Feasibility and Acceptability measure: Penn Emotion Recognition Test measure: Stop Distance Paradigm measure: Beck Depression Inventory measure: Spielberger State-Trait Anxiety Inventory measure: Prodromal Questionnaire- Brief measure: Connor-Davidson Resilience Scale sex: ALL minimumAge: 14 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Massachusetts General Hospital status: RECRUITING city: Charlestown state: Massachusetts zip: 02129 country: United States name: Daphne J Holt, MD, PhD role: CONTACT phone: 617-726-7618 email: dholt@mgh.harvard.edu name: Nicole DeTore, PhD role: CONTACT phone: 617-726-2065 email: ndetore@mgh.harvard.edu lat: 42.37787 lon: -71.062 hasResults: False
nctId: NCT06360549 id: TJ-IRB202403019 briefTitle: Effect of Percutaneous Acupoint Electrical Stimulation on Delirium overallStatus: RECRUITING date: 2024-03-01 date: 2024-12-30 date: 2025-06-30 date: 2024-04-11 date: 2024-04-11 name: Qin Zhang class: OTHER name: National Natural Science Foundation of China briefSummary: This study is a multicenter, prospective, randomized controlled clinical trial that aims to observe the impact of Transcutaneous Electrical Acupoint Stimulation (TEAS) on plasma TK/MMP3 in a randomized controlled setting. The intervention group received percutaneous acupoint electrical stimulation, whereas the control group underwent conventional treatment. The primary objective is to enhance the management of postoperative delirium, specifically focusing on the occurrence and severity of delirium following thoracoscopic pulmonary resection. Additionally, various perioperative inflammatory markers, cognitive function, recovery quality, pain levels, anxiety, sleep patterns, postoperative complications, and overall hospital stay duration were monitored to elucidate the mechanisms through which percutaneous acupoint electrical stimulation improves postoperative delirium. conditions: Delirium, Postoperative studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The intervention group was percutaneous acupoint electrical stimulation treatment group, and the control group was conventional treatment group.
4. ASA Grade I-III; primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 238 type: ESTIMATED name: Transcutaneous Electrical Acupoint Stimulation measure: Delirium (using the Delirium Rating Scale, DRS) measure: Mini-Mental State Examination (MMSE) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Guangdong Hospital of Traditional Chinese Medicine status: NOT_YET_RECRUITING city: Guangzhou state: Guangdong zip: 510000 country: China name: Jiemin Deng role: CONTACT phone: 2780 email: qin4298@sina.com name: Jiemin Deng role: CONTACT lat: 23.11667 lon: 113.25 facility: Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology status: RECRUITING city: Wuhan state: Hubei zip: 430030 country: China name: Qin Zhang, phd role: CONTACT phone: 15717154768 email: qzhang8@tjh.tjmu.edu.cn name: Qin Zhang, phd role: PRINCIPAL_INVESTIGATOR lat: 30.58333 lon: 114.26667 hasResults: False
nctId: NCT06360536 id: IRB-300012634 id: P50MD017338 type: NIH link: https://reporter.nih.gov/quickSearch/P50MD017338 briefTitle: Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women acronym: OVERCOME-IT overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2026-06-01 date: 2026-06-30 date: 2024-04-11 date: 2024-04-11 name: University of Alabama at Birmingham class: OTHER name: National Institute on Minority Health and Health Disparities (NIMHD) briefSummary: The purpose of this study is to collect preliminary data on the feasibility, acceptability, and potential effects of a novel, remotely delivered resistance training program. conditions: Overweight or Obesity conditions: Prediabetes or Diabetes conditions: Prehypertension (Elevated Blood Pressure) or Hypertension conditions: Resistance Training studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 36 type: ESTIMATED name: Resistance Training measure: Feasibility of recruitment measure: Feasibility of retention measure: Intervention adherence measure: Change in resistance training behaviors measure: Change in blood pressure measure: Change in HbA1C measure: Change in body composition measure: Change in handgrip strength measure: Change in the number of chair stands sex: FEMALE minimumAge: 30 Years maximumAge: 64 Years stdAges: ADULT facility: University of Alabama at Birmingham city: Birmingham state: Alabama zip: 35294 country: United States name: Jackie Grant role: CONTACT phone: 205-975-7108 email: jroche@uabmc.edu name: Amber Kinsey role: CONTACT phone: 205-934-9851 email: akinsey@uabmc.edu name: Amber W Kinsey, PhD role: PRINCIPAL_INVESTIGATOR lat: 33.52066 lon: -86.80249 hasResults: False
nctId: NCT06360523 id: CRE-2024.141 briefTitle: To Evaluate an MRI-based Optimized Prostate Cancer Diagnostic Pathway Powered by Artificial Intelligence overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-31 date: 2025-07-20 date: 2024-04-11 date: 2024-04-11 name: Chinese University of Hong Kong class: OTHER briefSummary: It is a prospective paired-cohort study for diagnostic test evaluation. The study aim to determine the accuracy of AI review and investigate whether AI review could detect MRI visible significant cancer as effective as radiologist review. MRI image of about 102 men recommended for biopsy will be reviewed by an AI model and an experienced radiologist, respectively. AI review (index) and radiologist review (standard) will be blinded to each other, while biopsy urologists will be well-informed of the findings of both AI review and radiologist review and make personalized biopsy plan by combining both findings. The pathological results of MRI-ultrasound fusion biopsy (reference) will serve as the gold standard to assess the diagnostic accuracy. conditions: Prostate Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 102 type: ESTIMATED name: AI modal measure: Prostate Cancer detection rate of ISUP grade group ≥2 measure: Diagnosis of any grade of prostate cancer sex: MALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Prince of Wales Hospital, Chinese University of Hong Kong city: Hong Kong country: Hong Kong lat: 22.27832 lon: 114.17469 hasResults: False
nctId: NCT06360510 id: 44 briefTitle: Comparison of %5 Dextrose and Betamethasone Injections in Patients With Carpal Tunnel Syndrome overallStatus: ACTIVE_NOT_RECRUITING date: 2023-05-05 date: 2024-05-05 date: 2024-05-05 date: 2024-04-11 date: 2024-04-11 name: Gaziler Physical Medicine and Rehabilitation Education and Research Hospital class: OTHER briefSummary: The aim of the study is to compare the effectiveness of ultrasound-guided betamethasone and 5% dextrose injection, which is routinely applied in clinical practice, in patients with mild and moderate carpal tunnel syndrome (CTS). conditions: Carpal Tunnel Syndrome studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 30 type: ACTUAL name: %5 dextrose injection name: betamethasone injection measure: vas measure: boston carpal tunnel syndrome questionnaire measure: median nerve cross sectional area measure: tinnel test positivity measure: phalen test positivity measure: duruöz hand index measure: global evaluation of treatment outcomes sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ankara Gaziler Physical Medicine and Rehabilitation Education and Research Hospital city: Ankara country: Turkey lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06360497 id: 202206090070 briefTitle: The Effect of Mindfulness Meditation and Loving-kindness and Compassion Meditation on Psychological Distress overallStatus: COMPLETED date: 2022-06-03 date: 2022-10-09 date: 2022-10-09 date: 2024-04-11 date: 2024-04-11 name: Beijing Normal University class: OTHER briefSummary: The purpose of the study is to explore the effect of of mindfulness meditation and loving-kindness and compassion meditation on psychological distress (i.e., anxiety, depression, stress), and explore the mechanism from the perspective of reinforcement sensitivity theory. conditions: MM Group conditions: LKCM Group conditions: Waitlist Group studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 152 type: ACTUAL name: mindfulness meditation intervention and loving-kindness and compassion meditation intervention measure: The Depression Anxiety Stress Scale measure: The Philadelphia Mindfulness Scale measure: The Sensitivity to Punishment and Sensitivity to Reward Questionnaire measure: The Emotional Word Lists sex: ALL minimumAge: 18 Years maximumAge: 56 Years stdAges: ADULT facility: Xianglong Zeng city: Beijing state: Beijing zip: 100875 country: China lat: 39.9075 lon: 116.39723 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2024-03-27 uploadDate: 2024-03-27T06:37 filename: Prot_SAP_000.pdf size: 125410 hasResults: False
nctId: NCT06360484 id: PrevelanceHDVSudan briefTitle: Prevalence and Clinical Characterization of Hepatitis D Virus (HDV) Infection Among Sudanese Patients With Hepatitis B Virus overallStatus: COMPLETED date: 2022-06-01 date: 2022-09-01 date: 2022-09-10 date: 2024-04-11 date: 2024-04-11 name: National Center for Gastroentestinal and Liver Disease class: OTHER briefSummary: Background: Sudan has a high prevalence of hepatitis B surface antigen (HBsAg), exceeding 8%. The prevalence of hepatitis B varies across different regions of Sudan, ranging from 6.8% in central Sudan to as high as 26% in southern Sudan. Hepatitis B virus (HBV) infection can lead to various complications, including cirrhosis, liver failure, and hepatocellular carcinoma (HCC). Hepatitis D virus (HDV) relies on HBV for replication and can accelerate the progression of HBV-related liver diseases, leading to more severe outcomes. This study aims to determine the prevalence of HDV infection among Sudanese patients with HBV-related liver diseases and to investigate the clinical characteristics of patients with HBV/HDV co-infection.
Design/Method: This descriptive cross-sectional hospital-based study was conducted at Ibn Sina Specialized Hospital in Sudan between June and September 2022. Ninety HBV patients aged 16 years and above were included. Patients were interviewed using a structured questionnaire, and medical histories and examinations were recorded. Investigations included liver function tests, abdominal ultrasounds, and ELISA for Ant-HDV-IgG conditions: Hepatitis B conditions: Hepatitis D conditions: Viral Hepatitis studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 90 type: ACTUAL name: investigations for Hepatitis D virus measure: the prevalence of hepatitis D infection among Sudanese patients with HBV-related liver diseases. sex: ALL minimumAge: 16 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: National Center for Gastrointestinal and Liver Diseases city: Khartoum zip: 15004 country: Sudan lat: 15.55177 lon: 32.53241 hasResults: False
nctId: NCT06360471 id: FS-FMC briefTitle: Fertility Preservation and Pregnancy and Offspring Health Outcomes in Female Cancer overallStatus: RECRUITING date: 2023-10-01 date: 2027-10-01 date: 2032-10-01 date: 2024-04-11 date: 2024-04-16 name: The First Affiliated Hospital with Nanjing Medical University class: OTHER briefSummary: To explore whether there is a significant difference in the cumulative live birth rate and maternal and child health outcomes between cancer patients who undergo or do not undergo fertility preservation before receiving anti-tumor treatment and non-cancer patients who undergo assisted reproductive technology treatment/natural pregnancy.
Statistical analysis of the data will be performed. conditions: Fertility Issues conditions: Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 2800 type: ESTIMATED name: fertility preservation measure: 5-year cumulative live birth rate measure: Ovarian function(AMH levels) measure: Ovarian function(AFC counts) measure: Newborn malformation rate measure: Tumor recurrence rate measure: Tumor survival rate sex: FEMALE minimumAge: 20 Years maximumAge: 40 Years stdAges: ADULT facility: Clinical Center of Reproductive Medicine of First Affiliated Hospital with Nanjing Medical University status: RECRUITING city: Nanjing state: Jiangsu zip: 210000 country: China name: Xiang Ma, MD. PHD role: CONTACT phone: +8618001581878 email: sxmaxiang@126.com name: Nan Lu role: CONTACT phone: +8615950476023 email: nancylu1993@126.com lat: 32.06167 lon: 118.77778 hasResults: False
nctId: NCT06360458 id: MRCTA,ECFAH of FMU[2024]368 briefTitle: Methylprednisolone Adjunctive to Endovascular Treatment for Stroke overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-01 date: 2028-03-01 date: 2024-04-11 date: 2024-04-11 name: Wan-Jin Chen class: OTHER briefSummary: The efficacy and safety of methylprednisolone in acute ischemic stroke patients with large infarct cores (ASPECTS score \< 6) due to anterior circulation large vessel occlusion have not been clearly established. This is a multi-center, randomized, double-blind, placebo-controlled trial to investigate early combination therapy with methylprednisolone for reperfusion in acute large core infarction. conditions: Acute Ischemic Stroke studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 735 type: ESTIMATED name: Methylprednisolone measure: Mortality at 90 days sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False