hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06278272 id: AIPEI briefTitle: AI Evaluation of Pancreatic Exocrine Insufficiency in CP Patients overallStatus: COMPLETED date: 2023-03-01 date: 2024-01-01 date: 2024-01-01 date: 2024-02-26 date: 2024-02-26 name: Changhai Hospital class: OTHER briefSummary: Early assessment of pancreatic exocrine insufficiency (PEI) is crucial for determining appropriate chronic pancreatitis (CP) treatment plans, thereby avoiding unnecessary suffering and further complications in patients. A total of 504 patients with CP who underwent fecal elastase-1 test and contrast-enhanced CT at Changhai Hospital between January 2018 and April 2023 were enrolled in this study. The investigators aim to establish a fully automated workflow to establish a PEI classification model based on radiomic features, semantic features and deep learning features on enhanced CT images for evaluating the severity of PEI. conditions: Chronic Pancreatitis conditions: Exocrine Pancreatic Insufficiency conditions: Machine Learning conditions: Deep Learning studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 504 type: ACTUAL measure: Classification of pancreatic exocrine insufficiency sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Changhai Hospital city: Shanghai zip: 200433 country: China lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06278259 id: P.T.REC/012/005023 briefTitle: Telerehabilitation Program Bases Aerobic and Baduanjin Exercises in Post Stroke Elderly Patients overallStatus: RECRUITING date: 2024-02-20 date: 2025-02-28 date: 2025-09-30 date: 2024-02-26 date: 2024-03-08 name: Cairo University class: OTHER briefSummary: It is an interventional study in which 60 stroke patients estimated to enroll according to random allocation and will divided into two groups. The study group participants will involve in Telerehabilitation sessions will be based on low-impact rhythmic movements, guided by video with the Baduanjin exercise program ,the control group will receive the same aerobic exercises only conditions: Stroke studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Telerehabilitation program bases aerobic and Baduanjin exercises name: Telerehabilitation program bases aerobic exercises measure: physical function measure: Cognitive function measure: sleep quality measure: participants' satisfaction with the program sex: ALL minimumAge: 65 Years maximumAge: 75 Years stdAges: OLDER_ADULT facility: Faculty of Physical Therapy status: RECRUITING city: Cairo state: Dokki zip: 11432 country: Egypt name: marwa M elsayed, phd role: CONTACT phone: 01156033818 phoneExt: 02 email: marwadd999@gmail.com name: marwa M elsayed, ph.d role: CONTACT phone: 01156033818 phoneExt: 02 email: marwadd999@gmail.com lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06278246 id: 050/2021 briefTitle: Investigating the Muscarinic System in Schizophrenia Using Positron Emission Tomography overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2029-02 date: 2029-02 date: 2024-02-26 date: 2024-02-26 name: Centre for Addiction and Mental Health class: OTHER briefSummary: Within the schizophrenia population, there are individuals that respond to first-line antipsychotic treatments while others do not. The availability of muscarinic M4 subtype receptors (M4R) may play a role as to whether a person with schizophrenia is responsive to first-line antipsychotics or not. The goal of this observational study is to compare the availability of M4R in antipsychotic-free patients with schizophrenia and matched healthy controls. In addition, M4R availability in schizophrenia patients will be examined in relation to response to first line antipsychotics and clinical and cognitive measures. This study may help better understand antipsychotic resistance in schizophrenia and lead to the development of new treatment options, particularly for cognitive deficits and negative symptoms. conditions: Schizophrenia conditions: Schizophreniform Disorders studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 58 type: ESTIMATED name: PET Scan measure: M4 receptor expression measure: Clinical Data Statistical Analysis measure: Statistical Analysis of Cognitive Data measure: Statistical Analysis of Psychopathological Personality Traits in Health Control Group sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Centre for Addiction and Mental Health city: Toronto state: Ontario zip: M5T1R8 country: Canada lat: 43.70011 lon: -79.4163 hasResults: False
nctId: NCT06278233 id: 2023/85-70 briefTitle: Bihemispheric Transcranial Direct Current Stimulation* on Speech Fluency acronym: TDCS overallStatus: RECRUITING date: 2024-02 date: 2024-06 date: 2024-09 date: 2024-02-26 date: 2024-02-26 name: Biruni University class: OTHER briefSummary: It will be determined whether bihemispheric stimulation (anodal to the left IFG and cathodal to the right IFG) is used with fluency-facilitating conditions for 5 consecutive days in individuals with stuttering and whether there is a difference in terms of the effects seen in speech fluency compared to the sham condition. conditions: Stuttering, Adult studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: In this study, a double-blind, randomized controlled research design from experimental research methods will be applied. primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: One researcher not involved in any aspect of the study will randomize participants to the sham and tDCS study arms using blocked randomization. To ensure blinding, one researcher will record the administration of the tDCS and assessments, while independent speech-language pathologists will monitor the assessment recordings and score the test items. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 36 type: ESTIMATED name: Transcranial direct current stimulation measure: Disfluent syllables measure: Stuttering Severity Instrument- Fourth Edition (SSI-IV) score measure: The Overall Assessment of the Speaker's Experience of Stuttering (OASES) score sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Biruni University status: RECRUITING city: Istanbul state: Zeytinburnu zip: 34015 country: Turkey name: Feyzanur Ocak, Slp role: CONTACT lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06278220 id: Corneal HOA briefTitle: Scheimpflug Versus Placido-disc System in Evaluation of Corneal Higher-Order Aberrations overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2026-07 date: 2027-02 date: 2024-02-26 date: 2024-02-28 name: Assiut University class: OTHER briefSummary: Aim of work:
To assess the agreement between placido-based topographer (wavelight allegro topolyzer vario) and scheimpflug -based (Oculus Pentacam ) regard measuring corneal higher order aberrations before and after LASIK. conditions: Corneal Higher-order Aberrations studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 36 type: ESTIMATED name: placido-based topographer (wavelight allegro topolyzer vario) and scheimpflug -based (Oculus Pentacam ) measure: Agreement between placido-based topographer (wavelight allegro topolyzer vario) and scheimpflug -based (pentacam) measure: Changes in high order aberrations after LASIK. sex: ALL minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Naglaa Moustafa city: Assiut country: Egypt lat: 27.18096 lon: 31.18368 hasResults: False
nctId: NCT06278207 id: 22731 briefTitle: An Observational Study Called FINEROD to Learn More About the Use of the Treatment Finerenone Including How Safe it is and How Well it Works Under Real-world Conditions acronym: FINEROD overallStatus: RECRUITING date: 2024-02-15 date: 2024-06-30 date: 2024-06-30 date: 2024-02-26 date: 2024-04-18 name: Bayer class: INDUSTRY briefSummary: This is an observational study, in which data from people in Japan with chronic kidney disease (CKD) together with type 2 diabetes (T2D) are studied. The participants in this study are already receiving the study treatment finerenone as part of their regular care from their doctors. In observational studies, only observations are made without specified advice or interventions. CKD is a long-term progressive decrease in the kidneys' ability to work properly. In people with T2D, the body does not make enough of a hormone called insulin, or does not use insulin well enough. The resulting high blood sugar levels can cause damage to the kidneys. CKD often occurs together with T2D or as a consequence of T2D. Finerenone works by blocking certain proteins, called mineralocorticoid receptors. By doing this, it may reduce damage to kidneys, heart and blood vessels. Finerenone was recently approved in the US and is now available for doctors to prescribe to people with CKD together with T2D. Consequently, there is a need to collect more information about how finerenone is used, its safety and how well it works under real-world conditions. The main purpose of this study is to collect and describe the characteristics of people with CKD and T2D who are receiving initiate finerenone treatment as prescribed by their doctors. To do this, the researchers will collect general information of the participants such as age or gender and data on kidney function and possible heart problems.
The data will come from a network of commercial electronic health records (EHRs) and national claims data in Japan. They cover the period from July 1st, 2021 until September 2023. Only already available data is collected and studied. There are no required visits or tests in this study. conditions: Chronic Kidney Disease conditions: Type 2 Diabetes Mellitus studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 2500 type: ESTIMATED name: Finerenone (BAY 94-8862) measure: Participants' characteristics at baseline in a cohort of participants with CKD and T2D who initiate finerenone. measure: Participants' comorbidities at baseline in a cohort of participants with CKD and T2D who initiate finerenone. measure: Participants' comedications at baseline in a cohort of participants with CKD and T2D who initiate finerenone. measure: Proportion of finerenone initiators with and without UACR measurements at baseline measure: Mean UACR in the subcohort with UACR measurements measure: Incidence rate of kidney failure in participants with CKD and T2D that initiate finerenone. measure: Incidence rate of a composite cardiovascular outcome in participants with CKD and T2D that initiate finerenone. measure: Drug utilization patterns in a cohort of participants with CKD and T2D that initiate finerenone. measure: Number of participants who initiate finerenone at a 10 mg dose daily measure: Proportion of participants who continue the original 10 mg dose daily at the 1, 3, 6, and 12 months mark measure: Proportion of participants who up-titrate from 10 mg daily dose to a 20 mg dose daily at the 1, 3, 6, and 12 months mark measure: Number of participants who initiate finerenone at a 20 mg dose daily measure: Proportion of participants who continue the original 20 mg dose daily at the 1, 3, 6, and 12 months mark measure: Proportion of participants who down-titrate from 20 mg daily dose to a 10 mg dose daily at the 1, 3, 6, and 12 months mark sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Bayer status: RECRUITING city: Berlin zip: 13353 country: Germany lat: 52.52437 lon: 13.41053 facility: Many Locations status: COMPLETED city: Multiple Locations country: Japan hasResults: False
nctId: NCT06278194 id: 22.11.2023.589 briefTitle: Masseter Muscle Thickness in Gasser Ganglion Radiofrequency Treatment overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2024-07-15 date: 2024-11-15 date: 2024-02-26 date: 2024-02-26 name: Başakşehir Çam & Sakura City Hospital class: OTHER_GOV briefSummary: Trigeminal neuralgia is common painful disorder in pain medicine clinics. Gasserian ganglion radiofrequency thermocoagulation is one of the treatment option in patients with trigeminal neuralgia in refractory cases. The most commonly involved branch in trigeminal neuralgia is the mandibular branch. Masseter muscle is innervated by mandibulary nerve branch of the trigeminal nerve.
In theoretical basis, muscles innervated by target nerve are affected from ablation procedure. In this study the primary aim is to evaluate the change of the masseter muscle thickness in patients treated by gasserian ganglion radiofrequency thermocoagulation. The results may also show possible functional effect of the procedure related with masseter muscle. conditions: Trigeminal Neuralgia conditions: Gasserian Ganglion; Lesion studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 30 type: ESTIMATED name: Gasserian Ganglion Radiofrequency Thermocoagulation measure: Masseter muscle thickness measure: Masseter muscle thickness measure: Masseter muscle thickness sex: ALL minimumAge: 40 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06278181 id: 2023/08/1545 briefTitle: Diabetes, Metabolic Syndrome and Risk of Malaria in Cameroon overallStatus: RECRUITING date: 2023-09-21 date: 2024-12-30 date: 2025-01-30 date: 2024-02-26 date: 2024-03-01 name: Karolinska Institutet class: OTHER name: University of Dschang name: European Foundation for the Study of Diabetes briefSummary: Non-communicable diseases (NCDs) such as diabetes are increasing in countries where malaria transmission is common. This study aims to investigate the relationship between NCDs and parasitic infections in Cameroon. The investigators will assess the risk of malaria, as well as other parasitic diseases, in a prospectively followed group of adults with diabetes, compared with those without diabetes. Malaria parasites and intestinal worms will be tested using blood and stool collected at four time points during a one-year follow-up. In addition, this project will investigate how natural protection against malaria is affected by diabetes and other risk factors for heart diseases. conditions: Malaria conditions: Diabetes Mellitus conditions: Metabolic Syndrome conditions: Endemic studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 400 type: ESTIMATED measure: asymptomatic malaria measure: symptomatic malaria measure: schistosoma infection measure: strongyloides infection sex: ALL minimumAge: 21 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Limbe Regional Hospital status: RECRUITING city: Limbe country: Cameroon name: George Awungafac, MD role: CONTACT phone: +23779750125 email: george.awungafac@ki.se lat: 4.02356 lon: 9.20608 hasResults: False
nctId: NCT06278155 id: CNR-IRIB-PRO-2024-001 briefTitle: Social Relations Training for Children With ASD overallStatus: RECRUITING date: 2023-04-17 date: 2025-01-15 date: 2025-04-28 date: 2024-02-26 date: 2024-02-26 name: Istituto per la Ricerca e l'Innovazione Biomedica class: OTHER name: Messina, Italy briefSummary: The following protocol was developed with the intention of significantly improving social skills by focusing on increasing relationship skills among children with ASD. Divided into two distinct parts, "Basic Social Relationships" and "Intermediate Social Relationships," the protocol has 4 stages for the former and 5 stages for the latter. Each phase is preparatory to the next, and in addition, a teaching procedure is implemented that adopts three prompt levels (partial, moderate and total), gradually aiming to reduce the assistance provided to encourage independent response. This gradual approach is designed to stimulate greater independence in social interactions.
In the control group, the therapist takes on the role of mediating interactions, helping and facilitating participants' responses. There is no involvement of a social robot; therefore,the therapist self acts directly to guide, reinforce and support the participants' social interactions. conditions: Autism conditions: Autism Spectrum Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 60 type: ESTIMATED name: Social relation training with social robot name: Traditional social relations training measure: Vineland-II (Vineland Adaptive Behavior Scales-II - Survey Intervention Form) sex: ALL minimumAge: 5 Years maximumAge: 10 Years stdAges: CHILD facility: Institute for Biomedical Research and Innovation (IRIB) - National Research Council (CNR) status: RECRUITING city: Messina zip: 98164 country: Italy name: Flavia Marino role: CONTACT phone: +393395798263 email: flavia.marino@irib.cnr.it name: Giovanni Pioggia role: CONTACT phone: +393203390892 email: giovanni.pioggia@irib.cnr.it name: Flavia Marino role: PRINCIPAL_INVESTIGATOR name: Germana Doria role: SUB_INVESTIGATOR name: Chiara Failla role: SUB_INVESTIGATOR name: Noemi Vetrano role: SUB_INVESTIGATOR name: Ileana Scarcella role: SUB_INVESTIGATOR name: Roberta Minutoli role: SUB_INVESTIGATOR name: Paola Chilà role: SUB_INVESTIGATOR name: Giovanni Pioggia role: SUB_INVESTIGATOR name: Alfio Puglisi role: SUB_INVESTIGATOR lat: 38.19394 lon: 15.55256 hasResults: False
nctId: NCT06278142 id: ERTELEME_1 briefTitle: Web-Based Cognitive Behavior Therapy for Procrastination overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-04 date: 2024-07 date: 2024-02-26 date: 2024-02-26 name: Anadolu University class: OTHER briefSummary: The main purpose of this study is to present the development process and project flow of an internet-based self-help intervention programme to reduce the level of procrastination among university students. conditions: Mental Health Issue studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: INVESTIGATOR count: 45 type: ESTIMATED name: Internet Based Intervention - GUIDED name: Internet Based Intervention - WİTHOUT GUİDANCE measure: Tuckman Procrastination Behaviour Scale measure: Cognitive Distortions Questionnaire measure: Time Management Scale measure: Attitude Scale for Internet-Based Interventions measure: Depression Anxiety Stress Scale-21 (DASS-21) measure: Sociodemographic Information Form sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06278129 id: 4146 briefTitle: Evaluation of the Diagnostic and Prognostic Efficacy of MRI in Acute Sensorineural Hearing Loss and Ménière's Disease acronym: MRI_SSHL/MD overallStatus: RECRUITING date: 2018-06-19 date: 2021-04-23 date: 2025-12-31 date: 2024-02-26 date: 2024-02-26 name: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico class: OTHER briefSummary: Evaluation of the diagnostic and prognostic efficacy of nuclear magnetic resonance imaging in patients with acute sensorineural hearing loss or in patients suffering from probable or definite MD. The neuroradiological and audiological evaluation are held on in the same day in order to better clarify the radiological and clinical correlates. conditions: Sudden Sensorineural Hearing Loss conditions: Meniere Disease conditions: Ménière's Vertigo conditions: Meniere's Disease Aggravated conditions: Inner Ear Disease studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 64 type: ESTIMATED name: Vestibular myogenic potentials measure: Evaluation of inner ear structures in MRI images sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Audiology and Neuroradiology - Milan (Italy) status: RECRUITING city: Milan zip: 20133 country: Italy name: Diego Zanetti, MD Prof role: CONTACT phone: 00390255033936 email: audiologia@policlinico.mi.it name: Federica Di Berardino, MD Prof role: PRINCIPAL_INVESTIGATOR name: Giorgio Conte, MD Prof role: PRINCIPAL_INVESTIGATOR lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06278116 id: 2024-ALIGNERSCLEANSIGN briefTitle: Comparison of Absorbance Values, Sensory Evaluations and Periodontal Effects of Five Different Products for Clean Aligners Cleansing overallStatus: RECRUITING date: 2024-03-01 date: 2024-06 date: 2024-06 date: 2024-02-26 date: 2024-03-05 name: University of Pavia class: OTHER briefSummary: The aim of the study is to evaluate the most efficient product for the cleaning of Invisalign® clear aligners (Align Technology Inc., San Jose, CA, USA) through objective and subjective assessments after the use of 5 different products. For each aligner, one product is used for 2 weeks until all of them are used, therefore 5 different aligners are required for the study. A periodontal evaluation is conducted to assess variations during the time frame of the study. conditions: Dental Malocclusion studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: BASIC_SCIENCE masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 20 type: ESTIMATED name: Aligners cleansing with water name: Aligners cleansing with dish soap Svelto name: Aligners cleansing with Polident Antibacterial Denture Cleaner name: Aligners cleansing with Invisalign Cleaning Crystals name: Aligners cleansing with Geldis measure: Change in adsorbance (A) value measure: Changes in patient's perception measure: Changes in Probing Pocket Depth (PPD) values measure: Changes in Gingival Index (GI) values measure: Changes in Bleeding on probing (BOP) measure: Change in Schiff Air Index - Dental sensitivity test measure: Change of the BEWE Index Basic Erosive Wear Examination measure: Change in plaque index (PI): sex: ALL minimumAge: 14 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia status: RECRUITING city: Pavia state: Lombardy zip: 27100 country: Italy name: Andrea Scribante, DDS, PhD role: CONTACT phone: +39 0382516223 email: andrea.scribante@unipv.it lat: 45.19205 lon: 9.15917 hasResults: False
nctId: NCT06278103 id: 2023PI113 briefTitle: Correlation Between Expression of Hormonal Receptors, Clinical Data, and Methylation Profile in Meningiomas (MethylRH-M) acronym: MethylRH-M overallStatus: ENROLLING_BY_INVITATION date: 2000-01-01 date: 2024-07-01 date: 2024-09-01 date: 2024-02-26 date: 2024-02-26 name: Central Hospital, Nancy, France class: OTHER briefSummary: This research aims to explore the relationship between hormonal receptor expression and the clinical and histopathological characteristics of meningiomas. The underlying hypothesis is that hormonal receptor expression, as well as the methylation profile of their gene promoters, are associated with specific aspects of meningiomas and patients' clinical outcomes. The main objective is to study the correlation between the immunohistochemical expression of hormonal receptors and clinicopathological data. The secondary objectif is to study the correlation between the methylation profile of hormonal receptor gene promoters and their immunohistochemical expression. conditions: Meningioma studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: OTHER count: 180 type: ESTIMATED measure: immunohistochemical expression of different hormonal receptors measure: methylation profile of the promoters of hormonal receptor genes sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06278090 id: AUDC briefTitle: Impact of Ursodeoxycholic Acid Treatment on the Gallbladder Polyp Evolution acronym: GALPOL overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2026-02 date: 2026-07 date: 2024-02-26 date: 2024-02-28 name: Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz class: OTHER briefSummary: The goal of this observational study is to learn about the impact of ursodeoxycholic acid treatment on the gallbladder polyp evolution in patients with gallbladder polyps that undergo follow up. The main question it aims to answer is: