To achieve this goal, patients fulfilling the eligibility criteria will be invited for a single study visit for the collection of blood. The extracted HIV virus will be sequenced through whole genome sequencing methods to identify the drug-resistance mutations. The study is conducted in 15-20 countries within six regions of the IeDEA cohort (International epidemiology Databases to Evaluate AIDS). conditions: Hiv studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 2600 type: ESTIMATED measure: Type of Integrase Drug Resistance Mutations (INSTI DRMs) at the time of failing a DTG-based regimen. measure: Prevalence of Integrase Drug Resistance Mutations (INSTI DRMs) at the time of failing a DTG-based regimen. measure: Time to virologic failure measure: Number of INSTI DRMs per patient measure: DTG drug resistance measure: Phenotypic resistance levels of novel DRMs sex: ALL minimumAge: 10 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Centro Medico Huesped status: RECRUITING city: Buenos Aires country: Argentina lat: -34.61315 lon: -58.37723 facility: Instituto Nacional de Infectiologia Evandro Chagas - Fiocruz status: RECRUITING city: Rio De Janeiro country: Brazil lat: -22.90278 lon: -43.2075 facility: Hopital de Jour du Centre Hospitalier Universitaire (CHU Souro Sanou) status: RECRUITING city: Bobo-Dioulasso country: Burkina Faso lat: 11.17715 lon: -4.2979 facility: National Centre for HIV/AIDS, Dermatology and STDs (NCHADS) status: RECRUITING city: Phnom Penh country: Cambodia lat: 11.56245 lon: 104.91601 facility: Regional Hospital Limbe status: RECRUITING city: Limbe country: Cameroon lat: 4.02356 lon: 9.20608 facility: Hospital Jamot status: RECRUITING city: Yaounde country: Cameroon lat: 3.86667 lon: 11.51667 facility: Centre de Traitement Ambulatoire status: RECRUITING city: Brazzaville country: Congo lat: -4.26613 lon: 15.28318 facility: Centre de Traitement Ambulatoire status: RECRUITING city: Pointe Noire country: Congo lat: -4.77609 lon: 11.86352 facility: ACONDA Centre de Prise en Charge et de Formation (CePReF) status: RECRUITING city: Abidjan country: Côte D'Ivoire lat: 5.30966 lon: -4.01266 facility: Centre médical de suivi des donneurs de sang, CNTS status: RECRUITING city: Abidjan country: Côte D'Ivoire lat: 5.30966 lon: -4.01266 facility: Moi University, AMPATH status: RECRUITING city: Eldoret country: Kenya lat: 0.52036 lon: 35.26993 facility: Lighthouse clinic status: RECRUITING city: Lilongwe country: Malawi lat: -13.96692 lon: 33.78725 facility: Martin Preuss Centre status: RECRUITING city: Lilongwe country: Malawi lat: -13.96692 lon: 33.78725 facility: Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán status: RECRUITING city: Mexico City country: Mexico lat: 19.42847 lon: -99.12766 facility: Research for Development, Einstein-Rwanda Research and Capacity Building Program status: RECRUITING city: Kigali country: Rwanda lat: -1.94995 lon: 30.05885 facility: National Institute for Medical Research (NIMR) status: RECRUITING city: Kisesa country: Tanzania lat: -3.08333 lon: 34.15 facility: HIV-NAT/Thai Red Cross AIDS Research Center (TRCARC) status: RECRUITING city: Bangkok country: Thailand lat: 13.75398 lon: 100.50144 facility: Ramathibodi Hospital, Mahidol University status: RECRUITING city: Bangkok country: Thailand lat: 13.75398 lon: 100.50144 facility: Masaka Regional Referral Hospital / AHF Uganda Cares status: RECRUITING city: Masaka country: Uganda lat: -0.33379 lon: 31.73409 facility: Mbarara University of Science and Technology / Mbarara ISS Clinic (MUST) status: RECRUITING city: Mbarara country: Uganda lat: -0.60467 lon: 30.64851 facility: Centre for Infectious Disease Research Zambia (CIDRZ) status: RECRUITING city: Lusaka country: Zambia lat: -15.40669 lon: 28.28713 facility: Newlands Clinic status: RECRUITING city: Harare country: Zimbabwe lat: -17.82772 lon: 31.05337 hasResults: False