hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06366698 id: 23-55 briefTitle: Intravenous Iron Versus Oral Iron for the Treatment of Iron Deficiency Anemia acronym: IDA overallStatus: RECRUITING date: 2023-11-21 date: 2025-12-30 date: 2025-12-30 date: 2024-04-16 date: 2024-04-16 name: Arrowhead Regional Medical Center class: OTHER briefSummary: This study aims to assess whether administering intravenous iron early in pregnancy, compared to standard oral iron treatment, can enhance hemoglobin levels before delivery and reduce the need for blood transfusions in patients with iron deficiency anemia. Patients diagnosed with iron deficiency anemia were randomly assigned to receive either oral or intravenous iron. Before treatment initiation, patients completed a symptom questionnaire baseline hemoglobin, and ferritin levels were measured. Follow-up visits occurred four weeks later and at 24 to 28 weeks gestation, involving reassessment of symptoms, laboratory testing, and monitoring of treatment adherence. Final hemoglobin levels were determined before delivery, and data on the need for blood transfusion at delivery were recorded. conditions: Iron Deficiency Anemia of Pregnancy studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Patients are initially randomized to either PO or IV iron, after the initial 4-week treatment patients in the PO iron group can switch to IV iron if labs continue to show persist iron deficiency anemia. primaryPurpose: TREATMENT masking: NONE count: 900 type: ESTIMATED name: Venofer 200 MG Per 10 ML Injection name: Ferrous sulfate measure: Hemoglobin difference measure: Ferritin difference measure: Delivery Hemoglobin measure: Rates of blood transfusion measure: Symptoms measure: Preterm delivery measure: Depression measure: Birthweight sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Arrowhead Regional Medical Center status: RECRUITING city: Colton state: California zip: 92324 country: United States name: Guillermo Valenzuela, MD role: CONTACT phone: 909-580-4145 email: jvalenzuelar@me.com name: Tina M Bui, DO role: PRINCIPAL_INVESTIGATOR name: Kristina Roloff, DO role: SUB_INVESTIGATOR name: Guillermo Valenzuela, MD role: SUB_INVESTIGATOR name: Lily Zhu, DO role: SUB_INVESTIGATOR name: Phoebe Jen, DO role: SUB_INVESTIGATOR name: Mary Tsaturian, MD role: SUB_INVESTIGATOR lat: 34.0739 lon: -117.31365 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2023-11-21 uploadDate: 2024-04-10T14:44 filename: ICF_000.pdf size: 165063 hasResults: False
nctId: NCT06366685 id: YJS20230170 briefTitle: Development and Initial Application of a Combined Exercise and Psychological Intervention Program for Patients After Esophagectomy acronym: Recovery overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-10-31 date: 2025-02-01 date: 2024-04-16 date: 2024-04-16 name: Mengmeng Yuan class: OTHER name: Anhui Medical University briefSummary: Esophageal cancer imposes a significant burden in China, accounting for over 60% of the global disease burden. While surgery remains a common and highly effective treatment for esophageal cancer, patients often experience multiple physical and psychological symptoms postoperatively, severely affecting their recovery outcomes and quality of life. Although existing exercise or psychological intervention programs have shown some effectiveness, issues such as relatively singular intervention content, imprecise intervention timing, and vague intervention details persist.
This project, based on previous research foundations (including the development of symptom measurement tools and the identification of key recovery periods), is guided by symptom management theory and knowledge translation models. Taking a perspective of the synergistic impact of physical and psychological symptoms, the study focuses on patients undergoing esophageal cancer surgery. Initially, evidence-based literature review, focus group interviews, and expert consultations were conducted to develop a combined exercise and psychological intervention program, integrating subjective (CSCA_EC) and objective (6MWT) measurement indicators, named "Recovery For EC." Subsequently, the program was preliminarily applied in clinical settings using a mixed-methods approach, combining quantitative quasi-experimental design (108 cases) and qualitative interviews to assess its acceptability. The final clinical trial version of the Recovery For EC program was developed to provide patients with a tool for self-monitoring recovery outcomes and offer clinical healthcare professionals guidance for implementing precise and personalized rehabilitation management. conditions: Esophageal Cancer conditions: Exercise Training conditions: Psychotherapy conditions: Rehabilitation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Exercise and Psychological Intervention measure: the Convalescence Symptom Assessment Scale for EsophageCtomy patients (CSAS_EC) measure: 6-Minute Walk Test measure: Hospital Anxiety and Depression Scale (HADS) measure: Postoperative Complications sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Anhui Medical University city: Hefei state: Anhui zip: 234000 country: China name: Mengmeng Yuan, Graduate role: CONTACT phone: 18205575607 email: 2510950595@qq.com name: Shaoxue Li, Graduate role: CONTACT phone: 18712335223 email: 2581558674@qq.com name: Shuwen Li, Professor role: PRINCIPAL_INVESTIGATOR lat: 31.86389 lon: 117.28083 hasResults: False
nctId: NCT06366672 id: 202312043 briefTitle: Evaluating the Human Immune Response to the JYNNEOS Vaccine overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-12 date: 2025-12 date: 2024-04-16 date: 2024-04-16 name: Washington University School of Medicine class: OTHER briefSummary: This study is designed to evaluate the magnitude and duration of the human adaptive immune response to the JYNNEOS Modified Vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccine in the blood, lung mucosa, skin and bone marrow. conditions: Vaccinia conditions: Virus Diseases studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Participants will be vaccinated with MVA-BN according to the FDA-approved labeling and immune responses in the blood, lung mucosa, skin, and bone marrow will be monitored prior to and following vaccination using phlebotomy, research bronchoscopy, skin punch biopsy, and bone marrow aspiration procedures. primaryPurpose: BASIC_SCIENCE masking: NONE count: 20 type: ESTIMATED name: JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) suspension for subcutaneous injection name: Phlebotomy name: Research bronchoscopy name: Skin punch biopsy name: Bone marrow aspiration measure: Change in magnitude of the MVA-BN antigen-specific T cell response in the blood measure: Change in magnitude of the MVA-BN antigen-specific antibody response in blood plasma measure: Change in magnitude of the MVA-BN antigen-specific T cell response in the lower airways measure: Change in magnitude of the MVA-BN antigen-specific antibody response in bronchoalveolar lavage fluid measure: Evaluate the magnitude and surface phenotype of T cells in the blood, airspace, and skin over time measure: Evaluate the magnitude and surface phenotype of B cells in the blood and bone marrow over time. sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Washington University in Saint Louis School of Medicine Emergency Care and Research Core city: Saint Louis state: Missouri zip: 63110 country: United States name: Jamie Mills role: CONTACT phone: 314-305-1054 email: jamiem@wustl.edu lat: 38.62727 lon: -90.19789 hasResults: False
nctId: NCT06366659 id: M2024049 briefTitle: Unraveling the Pathogenesis of Pruritus in Intrahepatic Cholestasis of Pregnancy overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2025-08-20 date: 2025-08-20 date: 2024-04-16 date: 2024-04-16 name: Peking University class: OTHER name: Peking University Third Hospital briefSummary: This study hopes identify the main pruritogens of ICP pruritus and provide new insights for the diagnosis, prediction, and treatment of ICP. Details are as follows: It is planned to include ICP confirmed pregnant women and healthy pregnant women who have given birth in the Peking University Third Hospital and Sichuan University West China Second University Hospital. Then progesterone sulfate levels in plasma samples will be quantified by High Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) and itch intensity will be quantified by questionnaires. Main study endpoint: To reveal new indicators of ICP diagnosis with high accuracy: single, multiple or combined indicators of progesterone sulfates and other molecules like bile acids; Secondary study endpoint: To determine whether progesterone sulfates can be used as an early screening indicator for ICP for disease prediction, specifically whether elevated levels of progesterone sulfates predate pruritus in pregnant women with ICP. conditions: Intrahepatic Cholestasis of Pregnancy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 600 type: ESTIMATED measure: Progesterone metabolites (levels in plasma) measure: Itch intensity measure: Total bile acids (levels in plasma) sex: FEMALE minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: Peking University Third Hospital city: Beijing state: Beijing zip: 100000 country: China name: Guangyi Lan role: CONTACT phone: 13176881226 email: Guangyi_lan@stu.pku.edu.cn name: Yulong Li role: PRINCIPAL_INVESTIGATOR name: Yuan Wei role: PRINCIPAL_INVESTIGATOR lat: 39.9075 lon: 116.39723 facility: Sichuan University West China Second University Hospital city: Chengdu state: Sichuan zip: 610001 country: China name: Guangyi Lan role: CONTACT phone: 13176881226 email: Guangyi_lan@stu.pku.edu.cn name: Yaoyao Zhang role: PRINCIPAL_INVESTIGATOR name: Xue Xiao role: PRINCIPAL_INVESTIGATOR lat: 30.66667 lon: 104.06667 hasResults: False
nctId: NCT06366646 id: 035901 briefTitle: Competency-based Intervention for Head Nurses overallStatus: COMPLETED date: 2022-12-01 date: 2023-04-30 date: 2023-04-30 date: 2024-04-16 date: 2024-04-16 name: Matrouh University class: OTHER briefSummary: Head nurses have a crucial leadership role in managing their units and providing high-quality and safe nursing care. Head nurse leadership competency and effectiveness are very essential to manage nursing care practices and management activities in their hospitals. Development leadership competency intervention programs would improve the head nurse's competency and effectiveness. conditions: Intervention conditions: Knowledge, Attitudes, Practice studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A quasi-experimental design primaryPurpose: HEALTH_SERVICES_RESEARCH masking: SINGLE maskingDescription: A quasi-experimental design utilized one group for pre-, post, and follow-up intervention. whoMasked: PARTICIPANT count: 90 type: ACTUAL name: Competency-based intervention measure: Questionnaire to measure head nurses' knowledge of leadership competency measure: Questionnaire to measure head nurses' ability to use leadership competency measure: Questionnaire to measure leadership effectiveness sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Faculty of Nursing, Matrouh University city: Mersa Matruh zip: 002 country: Egypt lat: 31.3529 lon: 27.23725 hasResults: False
nctId: NCT06366633 id: 2024P000713 id: 1K23AT012364-01 type: NIH link: https://reporter.nih.gov/quickSearch/1K23AT012364-01 briefTitle: Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2025-01-31 date: 2025-03-31 date: 2024-04-16 date: 2024-04-22 name: Jafar Bakhshaie class: OTHER name: National Center for Complementary and Integrative Health (NCCIH) briefSummary: The investigator aims to conduct an open pilot study (N=12; 10 completers) to test the feasibility, acceptability, and credibility of an asynchronous web-based mind-body intervention (Toolkit for Resilient Life beyond Pain and Substance Use; Web-TIRELESS) for adult patients with a comorbidity of non-traumatic painful upper-extremity condition(s) (NPUC) and risky substance use.
Participants will complete 4 on-demand video sessions at their own pace (approximate pace of 1 session per week) and complete baseline and post-test assessments. participants may also partake in an exit interview to provide feedback on Web-TIRELESS to further refine the program and study protocol for future iterations. conditions: Orthopedic Disorder conditions: Nontraumatic Injury conditions: Substance Use conditions: Upper Extremity Problem studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 12 type: ESTIMATED name: Web-TIRELESS measure: Credibility and Expectancy Questionnaire (CEQ) measure: Client Satisfaction Questionnaire to assess satisfaction with/acceptability of treatment measure: The User Experience Scale to assess participants' satisfaction with (acceptability of) web-based delivery measure: The percent of patients that agree to participate to assess feasibility of recruitment measure: Rate at which program was accepted, measured by attendance to assess acceptability of treatment measure: Adherence to homework measure: Rate of participant's completion of self-report measures to assess feasibility of assessments measure: Adverse Events measure: Graded Chronic Pain Scale (GCPS) measure: Disabilities of the Arm, Shoulder and Hand (DASH) measure: Patient Reported Outcomes Measurement Information System (PROMIS) Emotional Distress - Depression-Short Form 8b v1.0 measure: PROMIS Emotional Distress - Anxiety-Short Form 8b v1.0 measure: Pain Catastrophizing Scale (PCS) measure: Pain Anxiety Symptoms Scale - Short Form (PASS-20) measure: Pain Vigilance and Awareness Questionnaire (PVAQ) measure: Brief Experiential Avoidance Questionnaire (BEAQ) measure: Current Opioid Misuse Measure (COMM) measure: The Timeline Follow Back (TLFB) measure: Numerical Rating Scale (NRS) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Massachusetts General Hospital city: Boston state: Massachusetts zip: 02129 country: United States name: Jafar Bakhshaie, MD, PhD role: CONTACT phone: 617-643-7641 email: jbakhshaie@mgh.harvard.edu lat: 42.35843 lon: -71.05977 hasResults: False
nctId: NCT06366620 id: STUDY00003416 briefTitle: Examining the Feasibility, Acceptability, and Fidelity of Utilizing Parent Training Graduates as Peer Supports overallStatus: RECRUITING date: 2024-04-10 date: 2024-06-19 date: 2024-06-19 date: 2024-04-16 date: 2024-04-16 name: Seattle Children's Hospital class: OTHER briefSummary: Disruptive behavioral disorders are common in early childhood, affecting up to 15% of preschool-aged children. Behavioral parent training programs are a first-line evidence-based treatment for child disruptive behaviors. There is evidence showing that (a) these programs are effective in reducing disruptive behavior and improving long-term outcomes, and (b) there is an excellent return on investment for early intervention. Nevertheless, there is limited availability of behavioral parent training programs, particularly in rural settings, due to shortages of trained clinicians. Thus, there is a pressing need for expanding the mental healthcare workforce in rural/underserved areas. The study will involve an established parent-based behavioral intervention (First Approach Skills Training for Behavior; or FAST-B) with added pilot component incorporating parents who have previously been through parent behavioral management training programs as Peer Supports. conditions: Child Disruptive Behavior Disorders conditions: Parent Child Relationship conditions: Parent Management Training conditions: Peer Support conditions: Child Behavior Problems conditions: Challenging Behavior conditions: Positive Parenting studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 30 type: ESTIMATED name: FAST-B PEERS name: FAST-B (First Approach Skills Training - Behavior) measure: Acceptability of FAST-B PEERS measure: Acceptability of FAST-B measure: FAST-B PEERS support calls attended measure: Weekly Assessment of Child Behavior - P measure: Coping with Child Negative Emotions Scale measure: Strengths and Difficulties Questionnaire sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Seattle Children's status: RECRUITING city: Seattle state: Washington zip: 98115 country: United States name: Doug Mason role: CONTACT phone: 206-987-7000 email: doug.mason@seattlechildrens.org name: Alissa D Hemke, MD role: PRINCIPAL_INVESTIGATOR lat: 47.60621 lon: -122.33207 hasResults: False
nctId: NCT06366607 id: 0306066 briefTitle: Managing High-alert Medication Administration and Errors overallStatus: COMPLETED date: 2023-03-01 date: 2023-05-31 date: 2023-05-31 date: 2024-04-16 date: 2024-04-16 name: Matrouh University class: OTHER briefSummary: High-alert medications are drugs that may lead to serious harm when they are wrongly administered to patients. Safe medication administration is the crucial role of nursing staff. conditions: Knowledge conditions: Practice Nurse's Scope conditions: Competence conditions: Nurse's Role conditions: Error Disclosure studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 300 type: ACTUAL name: high-alert medication administration measure: Questionnaire to measure nurses' knowledge about high-alert medication administration measure: Questionnaire to measure medication safety climate measure: Questionnaire to measure nurses' competency measure: observational check list to measure nurses' practice during administration of high-alert medications measure: Questionnaire to measure errors associated with administering high-alert medications sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Faculty of Nursing, Matrouh University city: Mersa Matruh zip: 002 country: Egypt lat: 31.3529 lon: 27.23725 hasResults: False
nctId: NCT06366594 id: 0305897 briefTitle: First-line Nurse Manager Authentic Leadership Training Program overallStatus: COMPLETED date: 2022-12-01 date: 2023-04-30 date: 2023-04-30 date: 2024-04-16 date: 2024-04-16 name: Matrouh University class: OTHER briefSummary: Authentic leadership behavior is considered a mandatory strategy for enhancing the nurse manager capabilities and practice as well as achieving positive nurses' attitudes. conditions: Intervention studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP interventionModelDescription: A quasi-experimental research design primaryPurpose: OTHER masking: SINGLE maskingDescription: A quasi-experimental design utilized one group for pre-, post, and follow-up intervention. whoMasked: PARTICIPANT count: 37 type: ACTUAL name: Authentic leadership training program measure: Questionnaire to measure first-line nurse managers' knowledge about authentic leadership measure: questionnaire to measure authentic leadership behavior among first-line nurse managers measure: Questionnaire to measure nursing care self-efficacy measure: Questionnaire to measure nurses' trust in their workplace sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Faculty of Nursing, Matrouh University city: Mersa Matruh zip: 002 country: Egypt lat: 31.3529 lon: 27.23725 hasResults: False
nctId: NCT06366581 id: HD20240307 briefTitle: Transcriptomic Analysis of Incisional Hernia Based on High-throughput Sequencing Technology overallStatus: COMPLETED date: 2023-03-01 date: 2023-09-01 date: 2024-03-01 date: 2024-04-16 date: 2024-04-16 name: Fudan University class: OTHER briefSummary: This study included patients who underwent surgical treatment for incisional hernia and non-hernia conditions. Surgical specimens were collected for transcriptome sequencing to obtain the gene expression list. Then genes analyzed by Gene Ontology, protein interactions, and signaling pathway enrichment using the expression matrix. conditions: Incisional Hernia conditions: Extracellular Matrix Alteration studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 36 type: ACTUAL name: Transcriptomic analysis measure: the gene expression list sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hua Dong Hospital Affiliated to Fu Dan University city: Shanghai country: China lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06366568 id: CRO-2022-10-PG-MER-MW-JG briefTitle: Efficacy of a Eugenol-based Product to Improve the Quality of Toothbrushing and Relieving Gum Discomfort Areas overallStatus: COMPLETED date: 2024-02-19 date: 2024-03-06 date: 2024-03-06 date: 2024-04-16 date: 2024-04-16 name: Colgate Palmolive class: INDUSTRY briefSummary: The objective of this study is to evaluate the efficacy of a eugenol-based product in improving the quality of toothbrushing and relieving areas of gingival discomfort. This is a randomized, controlled, parallel, examiner-blind clinical trial. conditions: Plaque, Dental studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 86 type: ACTUAL name: fluoride toothpaste containing 1450 ppm of MFP in a PCC base and eugenol gum product name: fluoride toothpaste containing 1450 ppm of MFP in a PCC base measure: Turesky Modification of the Quigley & Hein Plaque Index measure: questionnaire sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Universitätsklinikum Carl Gustav Carus Technische Universität Dresden Department of Periodontology Fetscherstras city: Dresden zip: 01307 country: Germany lat: 51.05089 lon: 13.73832 hasResults: False
nctId: NCT06366555 id: 24-02-0268 briefTitle: The Role of Manual Twirling Acupuncture in Reducing Muscle Pain and Stiffness After Biceps Curling in Healthy Untrained Individuals overallStatus: NOT_YET_RECRUITING date: 2024-04-22 date: 2024-06-22 date: 2024-06-22 date: 2024-04-16 date: 2024-04-26 name: Indonesia University class: OTHER briefSummary: Regular physical activity can help to prevent and control non-communicable disease. WHO recommends at least in adults to do moderate-vigorous physical activity includes muscle strengthening. But regardless the importance and recommendations of physical activity, not all of the world's population does it .Biceps Curling is a popular physical exercise which easy to do , it can strengthen the muscles in the upper body. However based on the International Association for the Study of Pain (IASP) in individuals who just starting to do physical exercise may experience pain and can become a barrier to do physical activity, so an approach is needed to prevent this and acupuncture is one of them. Currently, a lot of acupuncture research has been carried out to reduce the condition pain and stiffness after weight training, but there are not many study using manual acupuncture twirling in this condition .