hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06266611 id: 23-0982 briefTitle: Cannabis for Palliative Care in Cancer acronym: ARCTiC overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2028-07-31 date: 2028-07-31 date: 2024-02-20 date: 2024-02-21 name: University of Colorado, Boulder class: OTHER briefSummary: Many cancer patients suffer from pain, sleep, and mood problems and are using cannabis to relieve these symptoms. Cannabis may provide such relief but may also produce negative side effects including cognitive impairment, an especially problematic issue for cancer patients, indicating more research on cannabis use in the cancer context is required. In this endeavor, the present study seeks to compare the use of hemp-derived CBD (Cannabidiol) with and without THC (Delta-9-tetrahydrocannabinol) versus placebo on measures of sleep, pain, mood, subjective and objective cognitive functioning, and quality of life within 185 cancer patients. conditions: Sleep conditions: Anxiety conditions: Depression conditions: Pain studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 185 type: ESTIMATED name: fsCBD Cannabidiol name: Placebo name: bsCBD Cannabidiol measure: Pain Interference measure: Pain Intensity measure: Pain Inventory measure: Sleep Disturbance measure: Sleep-Related Impairment measure: Depression/Anxiety measure: Fatigue measure: Health Related Quality of Life measure: Cognitive Function measure: Cognitive Function measure: Cognitive Function measure: Cognitive Function measure: Plasma Cannabinoids measure: PROMIS Pain Intensity (Right Now) measure: Drug Effects measure: Drug Effects measure: Drug Effects - Mood measure: Drug Effects - Cognitive measure: Drug Effects - Cognitive measure: Drug Effects - Cognitive measure: Drug Effects - Blood Cannabinoids measure: Polypharmacy measure: Polypharmacy measure: Polypharmacy sex: ALL minimumAge: 25 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Anschutz Health Sciences Building city: Aurora state: Colorado zip: 80045 country: United States name: Harmony Soffer, BA role: CONTACT phone: 925-334-4031 email: harmony.soffer@colorado.edu lat: 39.72943 lon: -104.83192 hasResults: False
nctId: NCT06266598 id: EU-TF-HA-01 briefTitle: Effectiveness of Antidiabetic Treatment Applied in Childhood Obesity overallStatus: COMPLETED date: 2019-11-17 date: 2021-08-20 date: 2021-10-27 date: 2024-02-20 date: 2024-02-20 name: HÜMEYRA ACIKAN class: OTHER briefSummary: In our study, there are 33 healthy children with normal weight (control group) and 52 obese children who will be treated with metformin. To observe the efficacy of the 3-month treatment before and after metformin treatment, Zn, Zinc α-2 Glycoprotein (ZAG), Peroxisome proliferation activating receptor γ (PPARγ), Leptin (LEP) and Adiponectin (ADIPO) levels were compared, as well as anthropometric measurements and routine biochemistry tests. conditions: Childhood Obesity conditions: Insulin Resistance studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: In our study, there are 33 healthy children with normal weight (control group) and 52 obese children who will be treated with metformin. To observe the efficacy of the 3-month treatment before and after metformin treatment, Zn, Zinc α-2 Glycoprotein (ZAG), Peroxisome proliferation activating receptor γ (PPARγ), Leptin (LEP) and Adiponectin (ADIPO) levels were compared, as well as anthropometric measurements and routine biochemistry tests. primaryPurpose: TREATMENT masking: NONE count: 52 type: ACTUAL name: Metformin measure: Insulin resistance (HOMA-IR) level measure: Weight loss rate sex: ALL minimumAge: 9 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Erciyes University city: Kayseri̇ state: Melikgazi zip: 38030 country: Turkey lat: 38.73222 lon: 35.48528 hasResults: False
nctId: NCT06266585 id: HX-B-2023090 briefTitle: Clinical Deterioration in Cerebral Venous Thrombosis: A Predictive Study overallStatus: COMPLETED date: 2023-01-01 date: 2023-12-31 date: 2024-01-01 date: 2024-02-20 date: 2024-02-20 name: Beijing Tiantan Hospital class: OTHER name: Beijing Chao Yang Hospital name: Beijing Friendship Hospital briefSummary: The objective of this retrospective, prospective, multicenter cohort study is to determine the risk factors for deterioration of CVT patients after admission and establish a scoring model for risk stratification of patients. This study included two stages, the first stage was to enroll CVT patients from a single center from 2017 to 2022 for modeling, and the second stage was to enroll CVT patients from three centers in 2023 for external validation conditions: Cerebral Venous Thrombosis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: OTHER count: 273 type: ACTUAL measure: Number of Participants with CVT deteriorated on radiology measure: Number of Participants with altered neurological function measure: Number of Participants with altered consciousness measure: Neurological function at 30th day after onset (mRS) measure: Emergency surgery rates sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Capital Medical University Affiliated Beijing Tiantan Hospital city: Beijing state: Beijing country: China lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06266572 id: 1R43DA055182-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R43DA055182-01 briefTitle: Overcoming Stigma and Improving Outcomes for SUDs Through Education, Engagement, and Empowerment acronym: OASIS overallStatus: COMPLETED date: 2021-09-30 date: 2023-09-29 date: 2023-09-29 date: 2024-02-20 date: 2024-03-01 name: Center for Social Innovation, Massachusetts class: OTHER briefSummary: C4 Innovations (C4) and partners at Yale University (Yale) and the West Haven VA Medical Center (WHVA) proposed to develop and test OASIS (Overcoming and Addressing Stigma in Substance Use Disorders), a web-based educational platform for primary care clinicians and individuals with Opioid Use Disorder. The major aims of the study were to:
After development of the prototype, the C4-Yale-WHVA team planned to test OASIS with patients (N = 30) and clinicians (N = 5) using validated measures and qualitative interviews to assess usability, satisfaction, knowledge, empowerment, and stigma. conditions: Opioid Use Disorder studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 19 type: ACTUAL name: Overcoming and Addressing Stigma in Substance Use Disorders (OASIS) measure: Open Minds Scale for Health Care Providers measure: Brief Opioid Stigma Scale measure: Perceived Stigma of Addiction Scale measure: Knowledge Check measure: System Usability Scale measure: Internalized Stigma of Mental Illness Scale measure: Recovery Empowerment Scale measure: Mental Health Seeking Attitudes Scale sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: West Haven VA Medical Center city: West Haven state: Connecticut zip: 06516 country: United States lat: 41.27065 lon: -72.94705 hasResults: False
nctId: NCT06266559 id: 202101896A3 briefTitle: Efficacy Evaluation of Chang Geng Healthy Drink on Patients With Non-alcoholic Fatty Liver Disease overallStatus: NOT_YET_RECRUITING date: 2024-02-15 date: 2024-03-20 date: 2025-12-31 date: 2024-02-20 date: 2024-02-20 name: Chang Gung Memorial Hospital class: OTHER briefSummary: For non-alcoholic fatty liver disease, there is currently no effective treatment options. Traditional Chinese medicine (TCM) has a long history of treating liver diseases. However, TCM treatment methods are diverse, and there is currently a lack of high-quality clinical research to confirm the efficacy of Chinese herbal medicine. Thereafter, Chang-Gung Healthy Drink which is a TCM based healthy drink may be used to alleviate the clinical adverse event of non-alcoholic fatty liver disease patients. conditions: Non-Alcoholic Fatty Liver Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 60 type: ESTIMATED name: Chang Geng Healthy Drink measure: Fatigue Visual Analogue Scale - Current fatigue level measure: Fatigue Visual Analogue Scale - Other daily specific task fatigue level measure: Laboratory Data (Linver Function Index) measure: Liver stiffness measurement (kPa) measure: Controlled attenuation parameter (dB/m) measure: Number of Participants With Clinical Significant Adverse Avent (Safety Measures) sex: ALL minimumAge: 20 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06266546 id: CRYOTXA briefTitle: Prophylactic Endobronchial Tranexamic Acid to Reduce Bleeding in Transbronchial Cryobiopsy acronym: CRYOTXA overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-03-01 date: 2024-02-20 date: 2024-03-26 name: Ascension Via Christi Hospitals Wichita, Inc. class: OTHER briefSummary: Transbronchial cryobiopsies are common procedures used to obtain tissue samples from airways for diagnostic purposes. While these procedures are safe, there is a risk of bleeding from the biopsy site. We are conducting a research study to assess the safety and effectiveness of using tranexamic acid prior to undergoing a transbronchial cryobiopsy. conditions: Hemorrhage Lung conditions: Endobronchial Mass studyType: INTERVENTIONAL phases: PHASE3 allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP interventionModelDescription: The study will be a prospective, single-arm, non-randomized trial primaryPurpose: PREVENTION masking: NONE count: 100 type: ESTIMATED name: Tranexamic acid measure: Major Hemorrhage measure: Early termination of the procedure due to bleeding measure: Rate of intermediate hemorrhage measure: Rate of minor hemorrhage measure: Inadequate tissue sampling due to bleeding measure: Graded use of other measures to control bleeding (not prophylactic) measure: Unplanned hospital admission for bleeding complications measure: Acute cardiovascular side effects measure: All cause 28 day mortality sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ascension Via Christi city: Wichita state: Kansas zip: 67214 country: United States lat: 37.69224 lon: -97.33754 hasResults: False
nctId: NCT06266533 id: Pro2023002473 briefTitle: Dismantling the U.S. Social Norm of the "Kids' Food" Archetype (REACH Project) overallStatus: RECRUITING date: 2024-02-21 date: 2024-07-01 date: 2024-07-01 date: 2024-02-20 date: 2024-03-08 name: Rutgers, The State University of New Jersey class: OTHER briefSummary: This project is the first stage of a health promotion campaign to shift social norms about marketing and feeding children ultra-processed foods. Embedded within a longitudinal ethnographic study using photo-elicitation techniques, mothers of preschool-age children will be randomly assigned to arts-based or traditional education about ultra-processed food. conditions: Food Selection conditions: Environmental Exposure studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Participants will be randomly assigned to a conventional nutrition education or an arts-based education group. primaryPurpose: PREVENTION masking: NONE count: 38 type: ESTIMATED name: Conventional Ultra-processed Food Nutrition Education name: Arts-based Ultra-processed Food Nutrition Education measure: Ultra-Processed Food Knowledge measure: Environmental assessment of ultra-processed food sex: FEMALE minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Leaguers Inc. Head Start status: RECRUITING city: Newark state: New Jersey zip: 07102 country: United States name: Aurthur Nabi role: CONTACT phone: 973-643-0300 email: "arthuarthur_nabi@theleaguers.org lat: 40.73566 lon: -74.17237 hasResults: False
nctId: NCT06266520 id: DongyangH briefTitle: MNK Therapy in Releasing the Superficial Fascia for Patients With AAS: an Assessor-blinded, Randomised Controlled Trial overallStatus: RECRUITING date: 2023-01-01 date: 2025-06-01 date: 2025-06-01 date: 2024-02-20 date: 2024-02-20 name: Sen-wei Lu class: OTHER briefSummary: The goal of this type of randomized controlled trial, employing a blinded evaluator methodology, to verify the clinical efficacy and safety of MNK therapy. This aims to provide a reference for clinical practitioners and AAS patients in their decision-making process.
Participants will randomly allocated into two groups using a random number table method, with forty patients in each group. The experimental group (Group 1) underwent MNK therapy to release the superficial fascia, while the control group (Group 2) received conventional acupuncture treatment. conditions: Acute Ankle Sprain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 80 type: ESTIMATED name: MNK therapy to release the superficial fascia name: acupuncture measure: Visual Analogue Scale (VAS) measure: Kofoed Ankle Score sex: ALL minimumAge: 16 Years maximumAge: 55 Years stdAges: CHILD stdAges: ADULT facility: The Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, China status: RECRUITING city: Dongyang state: Zhejiang zip: 322100 country: China name: Sen-wei Lu, Dr. role: CONTACT phone: +8613989441117 email: lswlsw1121@163.com lat: 29.26778 lon: 120.22528 hasResults: False
nctId: NCT06266507 id: 169 briefTitle: Examining the Effect of Occupational Therapy-Based Parent Coaching on Feeding Problems in Children With a Preterm Birth overallStatus: NOT_YET_RECRUITING date: 2024-02-15 date: 2025-02-15 date: 2025-03-15 date: 2024-02-20 date: 2024-02-20 name: Ankara Medipol University class: OTHER briefSummary: Feeding problems are common in children with a history of premature birth, and these problems continue into early childhood. Feeding problems are affected by many biopsychosocial factors, and the context in which feeding takes place and the attitudes and behaviors of parents can also be effective in the emergence or continuation of these problems. The aim of our study is to evaluate the effects of occupational therapy-based parent coaching intervention on mothers and their children, who are considered to be primarily responsible for the feeding of children in our country. 46 mothers with premature children will be included in our study and participants will be randomly assigned to intervention/control groups. Mothers will fill out a sociodemographic information form, Behavioral Pediatric Feeding Assessment Scale, Sensory Profile Questionnaire - Oral Sensory Processing Subtest, Family Feeding Strategies Scale and Parental Self-Efficacy Scale via Google forms. Mothers in the research group will be given online occupational therapy-based parent coaching training for 10 weeks. Second evaluations will be carried out after the training; Final evaluations will be applied after 1 month of follow-up. conditions: Feeding Behavior conditions: Mother-Child Relations conditions: Feeding and Eating Disorders studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 46 type: ESTIMATED name: Ergotherapy Based Parent Coaching name: Informative Brochure Distribution measure: Behavioral Pediatric Feeding Assessment Scale measure: Sensory Profile Questionnaire - Oral Sensory Processing Test measure: Feeding Strategies Quesstionnaire measure: Parental Self-Efficacy Scale sex: FEMALE stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Ankara Medipol University city: Ankara state: Ankara/ Altındağ zip: 06110 country: Turkey lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06266481 id: pua04202312313157 briefTitle: Topical Dexamethasone Versus Topical Lidocaine Spray to Reduce POST in Shoulder Arthroscopic Surgeries: A Comparative Study acronym: post overallStatus: RECRUITING date: 2024-03-01 date: 2024-04-30 date: 2024-05-30 date: 2024-02-20 date: 2024-02-20 name: Pharos University in Alexandria class: OTHER briefSummary: postoperative sore throat is the most frequent side effects after anaesthesia intubation. Dexamethasone and 10% lidocaine spray used prior to surgery has shown useful in managing these complications at the moment. In order to examine the prophylactic impact of local Dexamethasone and lidocaine on postoperative sore throat, this study was conducted. conditions: Postoperative Sore Throat studyType: INTERVENTIONAL phases: PHASE2 phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 100 type: ESTIMATED name: Topical dexamethasone name: 10% lidocaine was sprayed over the tube for the second group measure: Topical dexamethasone versus topical lidocaine spray to reduce post-intubation sore throat in shoulder arthroscopic surgeries: A comparative study sex: ALL minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Pharos University status: RECRUITING city: Alexandria zip: 21348 country: Egypt name: mona el. massoud, ph anesthesia role: CONTACT phone: 002+01005542232 email: mona.elsaid@pua.edu.eg name: hatem a. attalla, ph anaesthesia role: CONTACT phone: 002+1001445568 email: hatattalla@hotmail.com name: mona el. massoud, lecture role: PRINCIPAL_INVESTIGATOR lat: 31.21564 lon: 29.95527 hasResults: False
nctId: NCT06266468 id: STUDY00149178 briefTitle: Nutricity: An mHealth Nutrition Intervention to Improve Diet Quality Among Latino Children overallStatus: NOT_YET_RECRUITING date: 2024-02-21 date: 2025-06-30 date: 2025-12-31 date: 2024-02-20 date: 2024-02-20 name: University of Kansas Medical Center class: OTHER briefSummary: The overall objective of this application is to pilot test an mHealth nutrition intervention within pediatric clinics serving Latino families and evaluate its potential for implementation. The investigators hypothesize the intervention will improve child diet quality and will be feasible for use within the clinic setting. To test this hypothesis, the investigators will pursue 3 specific aims and 1 exploratory aim:
4. Exploratory Aim 1: Explore the relationship among nutrition literacy, psychosocial constructs and diet quality outcomes; and explore how engagement and satisfaction influence outcomes. conditions: Diet Quality studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The intervention study model is a 2-arm randomized control trial with a 1:1 allocation of participants to the treatment group (Nutricity) or the control group (usual care without Nutricity). After 12 weeks in the control group, participants will be introduced to Nutricity. primaryPurpose: PREVENTION masking: NONE count: 80 type: ESTIMATED name: Nutricity measure: Change in Diet quality (Healthy Eating Index) (child) measure: Nutrition Literacy (parent) measure: Body Mass Index (child) measure: Skin Carotenoid measure: Feeding Behaviors of Parent and Children measure: Mediation of Children's Media Use measure: Parent Self-Efficacy measure: Parent Nutrition Attitudes sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06266455 id: Pro00000615 briefTitle: Individualized Nutrition to Optimize Preterm Infant Growth and Neurodevelopment acronym: THRIVE overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2034-01 date: 2034-01 date: 2024-02-20 date: 2024-02-28 name: Children's National Research Institute class: OTHER briefSummary: Human milk has several well-established benefits but does not adequately meet the increased nutritional demands of the growing preterm infant, necessitating additional nutrient supplementation in a process known as fortification. In U.S. neonatal intensive care units (NICUs), human milk is primarily supplemented using standardized fortification, in which a multicomponent fortifier is added to human milk to achieve assumed nutrient content based on standard milk reference values. However, this method does not account for the significant variability in human milk composition or in preterm infant metabolism, and up to half of all very premature infants experience poor growth and malnutrition using current nutritional practices. Poor postnatal growth has adverse implications for the developing preterm brain and long-term neurodevelopment.
Recent advances allow for individualized methods of human milk fortification, including adjustable and targeted fortification. Adjustable fortification uses laboratory markers of protein metabolism (BUN level) to estimate an infant's protein requirements. In targeted fortification, a milk sample is analyzed to determine its specific macronutrient and energy content, with additional macronutrient supplementation provided as needed to achieve goal values. Emerging data suggest that both methods are safe and effective for improving growth, however information on their comparable efficacy and neurodevelopmental implications are lacking, particularly using advanced quantitative brain MRI (qMRI) techniques.
Through this prospective, randomized-controlled trial, the investigators will compare the impact of individualized human milk fortification on somatic growth and neurodevelopment in preterm infants. Infants will be randomized to receive one of three nutritional interventions: standardized (control group), adjustable, or targeted human milk fortification. Infants will undergo their assigned nutritional intervention until term-equivalent age or discharge home, whichever is achieved first. Brain qMRI will be performed at term-corrected age, and neurodevelopmental follow-up will be performed through 5 years of age. conditions: Very Preterm Maturity of Infant conditions: Very Low Birth Weight Infant studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Prospective, randomized-controlled trial comparing the impact of individualized human milk fortification on somatic growth and neurodevelopment in preterm infants randomized to receive one of three nutritional interventions: standardized (control), adjustable, or targeted human milk fortification. primaryPurpose: SUPPORTIVE_CARE masking: SINGLE maskingDescription: Due to the nature of the nutritional interventions, the clinical and research teams will not be blinded to study intervention. The radiologist and research team members performing MRI interpretation, post-acquisition processing, and quantitative analysis will be blinded to study nutritional intervention arm. Similarly, teams performing neurodevelopmental follow-up will also be blinded to study nutritional intervention arm. whoMasked: OUTCOMES_ASSESSOR count: 150 type: ESTIMATED name: Standardized Fortification name: Adjustable Fortification name: Adjustable Fortification measure: Weight Gain Velocity measure: Length Growth Velocity measure: Head Circumference Growth Velocity measure: Total and Regional Brain Volumes measure: Neonatal Intensive Care Unit Network Neurobehavioral Scale (NNNS) measure: Mullen Scales of Early Learning (MSEL) measure: Mullen Scales of Early Learning (MSEL) measure: Wechsler Preschool and Primary Scale of Intelligence (4th edition) (WPPSI-IV) measure: Differential Abilities Scale (2nd edition)-(DAS-II) sex: ALL maximumAge: 4 Weeks stdAges: CHILD facility: Children's National Hospital city: Washington state: District of Columbia zip: 20010 country: United States name: Catherine Limperopoulos, Ph.D. role: CONTACT phone: 202-476-5293 email: CLimpero@childrensnational.org name: Katherine M. Ottolini, M.D. role: CONTACT phone: 202-476-8905 email: KOttolin@childrensnational.org name: Catherine Limperopoulos, Ph.D. role: PRINCIPAL_INVESTIGATOR lat: 38.89511 lon: -77.03637 hasResults: False