hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06322589 id: CMUH112-REC3-175 briefTitle: Evaluation of Human Efficacy of SOD Like Super Drink overallStatus: RECRUITING date: 2024-03-01 date: 2024-10-31 date: 2024-12-31 date: 2024-03-21 date: 2024-03-21 name: TCI Co., Ltd. class: INDUSTRY briefSummary: To assess the efficacy of SOD like Super Drink on anti-oxidant capacity, immuno regulation and skin for human conditions: Dermatology studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 50 type: ESTIMATED name: SOD like Super Drink name: placebo drink measure: the volume of skin wrinkles measure: the roughness of skin texture measure: the change of skin elasticity measure: the change of Total Anti-oxidative Capacity (TAC) of blood measure: the change of Superoxide Dismutase (SOD) of blood measure: the change of Glutathione S-transferase (GST) of blood measure: the change of Glutathione (GSH) of blood measure: the change of Malondialdehyde (MDA) of blood measure: the change of immune-related cytokines of blood measure: the change of skin surface hydration measure: the change of skin Transepidermal Water Loss (TEWL) measure: the change of Skin Melanin Index measure: the change of Skin Erythema Index measure: The change of liver function biomarkers (AST, ALT) of blood measure: The change of renal function biomarkers (creatinine, BUN) of blood measure: The change of self-assessment skin condition and immuno condition sex: ALL minimumAge: 30 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: China Medical University of department of cosmeceutics status: RECRUITING city: Taichung City zip: 406040 country: Taiwan name: Hsiu-Mei Chiang, Ph.D. role: CONTACT phone: +886-04-22053366 phoneExt: 5302 email: hmchiang@mail.cmu.edu.tw name: Ping Lin role: CONTACT phone: +886-02-879778111 email: candice.lin@tci-bio.com lat: 24.1469 lon: 120.6839 hasResults: False
nctId: NCT06322576 id: IRB00347750 briefTitle: 177Lu-PSMA (177Lu-PNT2002) in PSMA-Positive Adenoid Cystic Carcinoma overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2030-12 date: 2035-12 date: 2024-03-21 date: 2024-03-22 name: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins class: OTHER name: Adenoid Cystic Carcinoma Research Foundation name: Progenics Pharmaceuticals, Inc. briefSummary: This is a single arm trial with one Cohort for people with recurrent or metastatic adenoid cystic carcinoma that cannot be treated with surgery. 10 participants will be enrolled in Cohort 1 at Johns Hopkins and will undergo DCFPyL PET/CT and 177Lu-PSMA dosimetry imaging only (single tracer dose). A feasibility analysis of dosimetry will be performed after meeting the accrual goal of Cohort 1 to determine if the study will proceed into Cohort 2.
If Cohort 2 proceeds, based on the dosimetry analysis, the major requirements of the study are to undergo treatment with 177Lu-PNT2002, have bloodwork, physical exams, and imaging done at study-specific time points, and to answer questionnaires. Patients will be in the study for about two years after enrolling. conditions: Adenoid Cystic Carcinoma studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Cohort 1of this study involves only Dosimetry for (10 patients).
(Cohort 2 may be added based on dosimetry analysis of Cohort 1. Planned Treatment for would be for 20 patients, single arm). primaryPurpose: TREATMENT masking: NONE count: 10 type: ESTIMATED name: 177Lu-PNT2002 measure: Absorbed dose in tumor and normal organs measure: Objective response rate (ORR) by RECIST 1.1 measured in patients treated with 177Lu-PSMA for recurrent and metastatic ACC. measure: Stability of Disease: Proportion of patients with Stable Disease measure: Progression Free Survival measure: Overall Survival measure: Duration of Response measure: Xerostomia questionnaire (XQ) score measure: European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Module (EORTC QLQ-HN43) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Johns Hopkins Hospital city: Baltimore state: Maryland zip: 21287 country: United States lat: 39.29038 lon: -76.61219 hasResults: False
nctId: NCT06322563 id: LTC004-202 briefTitle: Combination of LTC004 and Regorafenib to Treat Patients With Advanced/Metastatic CRC overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-03-01 date: 2025-03-01 date: 2024-03-21 date: 2024-03-21 name: Tianjin Medical University Cancer Institute and Hospital class: OTHER briefSummary: This is a phase II clinical study to evaluate the safety, tolerability and preliminary antitumor activity of LTC004 in combination with regorafenib in patients with mCRC. A safety introductory trial was conducted to receive LTC004 in combination with regorafenib before starting the formal trial. After completing a 28-day safety assessment, safety will be confirmed before entering the formal trial phase. Further evaluation of the safety and efficacy of LTC004 in combination with regorafenib in the treatment of mCRC conditions: Advanced/Metastatic Colorectal Cancer studyType: INTERVENTIONAL phases: PHASE2 allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: NONE count: 20 type: ESTIMATED name: LTC004+regorafenib measure: Treatment-Emergent Adverse Events-Safety and Tolerability measure: SAE-Safety and Tolerability measure: ORR measure: DCR measure: PFS measure: OS sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Tianjin Medical University Cancer Institute and Hospital city: Tianjin state: Tianjin zip: 300060 country: China lat: 39.14222 lon: 117.17667 hasResults: False
nctId: NCT06322550 id: beingapatient briefTitle: Influence of Role-expectancy on Patient Reported Outcomes Among Patients With Migraine: a Randomized Clinical Trial overallStatus: COMPLETED date: 2019-10-29 date: 2023-02-01 date: 2023-02-01 date: 2024-03-21 date: 2024-03-21 name: Universitätsklinikum Hamburg-Eppendorf class: OTHER briefSummary: This study was preregistered 2019 under https://osf.io/nczhj. Since JAMA requires a registration with ClinicalTrials.gov, we post-register the study here with the identical informations from OSF (see there)
Migraine is frequently associated with motion sickness, vestibular symptoms, and abnormal motion and visual processing. Clinical symptoms and underlying brain mechanisms during self-motion visual stimulation were not yet investigated in this population. Therefore the aim is to investigate the behavioral responses from a visually simulated roller coaster ride of patients with migraine and headache-free controls. In order to verify the effect of response bias, part of the patients with migraine will be informed that the study aims to investigate vestibular disorders instead of headache disorders and that they are invited as healthy controls. conditions: Role-expectancy on Patient Reported Outcomes studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Monocenter, randomized, double blind, three-armed clinical trial primaryPurpose: BASIC_SCIENCE masking: DOUBLE maskingDescription: Double blind whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 366 type: ACTUAL name: cover story measure: self-reported vestibular symptoms measure: differences in motion sickness susceptibility using a standardized motion sickness questionnaire measure: differences in disability level using a standardized motion sickness questionnaire measure: differences in headache days per month measure: differences in headache burden and migraine disability questionnaires sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: UKE city: Hamburg zip: 20246 country: Germany lat: 53.57532 lon: 10.01534 hasResults: False
nctId: NCT06322524 id: FirstShanxiMU_jsk briefTitle: Study on Gamma Sensory Flicker for Insomnia overallStatus: COMPLETED date: 2021-05-01 date: 2022-03-30 date: 2022-12-30 date: 2024-03-21 date: 2024-03-21 name: The First Affiliated Hospital of Shanxi Medical University class: OTHER name: Shanxi Medical University briefSummary: This prospective observational study enrolled adult volunteers for a sleep quality research study through a questionnaire survey distributed via a WeChat two-dimensional code from May 2021 to April 2022. Participants were exposed to flicker stimulation through a light and sound device for a duration of 8 weeks with daily monitoring. conditions: Sleep Quality conditions: Sleep Duration conditions: Sleep Onset Latency studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 37 type: ACTUAL name: Gamma sensory flicker measure: Treatment adherence rate measure: Patient treatment adherence rate measure: Incidence rate of adverse reaction measure: Differences in sleep duration between the first and eighth weeks measure: Differences in sleep onset latencies between the first and eighth weeks measure: Differences in awakening times between the first and eighth weeks measure: pre-sleep efficiency. measure: post-sleep efficiency. sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Yong Xu city: Taiyuan state: Shanxi zip: 030000 country: China lat: 37.86944 lon: 112.56028 hasResults: False
nctId: NCT06322511 id: HUS/7626/2023 briefTitle: Dialogical Family Guidance PostDoc Study acronym: DFG II overallStatus: RECRUITING date: 2024-01-02 date: 2027-12-31 date: 2027-12-31 date: 2024-03-21 date: 2024-03-21 name: Tampere University class: OTHER briefSummary: This new family intervention, called Dialogical Family Guidance (DFG) is developed to target family needs especially in families with a child with neurodevelopmental disorders. PhD study showed, that this intervention is functioning with this target group. Participants (families) experienced that they got information, guidance to ordinary life and that the DFG-therapists were listening to them and above all, helping with individual problems and questions. DFG include six meetings and professionals need to attend on a 3-day long education before using this intervention. conditions: Family Dynamics conditions: Family Relations conditions: Family Support studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Families attending the study Group I: receives Dialogical Family Guidance intervention and they fill questionnaires before and after the intervention.
Group II: Families do not receive Dialogical Family Guidance (but belong to the same focus group) primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE maskingDescription: Families include both parents and children. Parents fill the questionnaires, but all family members attend on the meetings during the intervention (six meetings). whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 50 type: ESTIMATED name: Dialogical Family Guidance (DFG) measure: FAFHES measure: DFG-questionnaire measure: SDQ-p questionnaire (Strengths and difficulties regarding the child) sex: ALL minimumAge: 4 Years maximumAge: 13 Years stdAges: CHILD facility: Helsinki university hospital status: RECRUITING city: Helsinki zip: 00029 country: Finland lat: 60.16952 lon: 24.93545 hasResults: False
nctId: NCT06322498 id: INFLAM.UTERUS-HMO-CTIL briefTitle: Inflammation Markers in Fluid Aspirate From a Scarred Uterine vs. a Normal Uterine Cavity overallStatus: RECRUITING date: 2023-01-18 date: 2024-12 date: 2024-12 date: 2024-03-21 date: 2024-03-21 name: Hadassah Medical Organization class: OTHER briefSummary: A prospective study that will take place in the hydrosonography clinic, comparing patients with an intact uterus to those who had a caesarean section. Eligible patients will preform a transvaginal ultrasound for evaluation of presence of a niche. After fixation of the transcervical catheter, we will flush 2 ml sterile NaCl 0.9% into the uterine cavity and aspirate the fluid. After collecting all samples, the samples will be snap frozen and stored at -80o C, until they undergo an immunological analysis. conditions: Infertility Due to Nonimplantation conditions: Infertility Secondary conditions: Cesarean Section Complications studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: DIAGNOSTIC masking: NONE count: 100 type: ESTIMATED name: Uterine lavage measure: Inflammatory cell population sex: FEMALE minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: Hadassah Medical Organization status: RECRUITING city: Jerusalem country: Israel name: Hadas Lemberg, PhD role: CONTACT phone: 00 972 2 6777572 email: lhadas@hadassah.org.il name: Chana Adler Lazarovits, MD role: PRINCIPAL_INVESTIGATOR lat: 31.76904 lon: 35.21633 hasResults: False
nctId: NCT06322485 id: P16.230 briefTitle: Online Self-management in Fibromyalgia overallStatus: COMPLETED date: 2017-01-25 date: 2021-01-26 date: 2021-01-26 date: 2024-03-21 date: 2024-03-21 name: Leiden University class: OTHER name: Fibrocentrum briefSummary: This study has been previously registered with the National Trial Registry (NTR6267) that has been cancelled. The registered trial has been automatically transferred to a new "Landelijk Trial Register", which does not contain all correct information on the current study and where no corrections can be made. Hence, the current study has been registered again with ClinicalTrials.gov.
The goal of this clinical trial is to study the effectiveness of an internet-based self-management intervention in adult patients with fibromyalgia. A randomized controlled trial (RCT) will be performed, in which 70 participants will be randomized to either the self-management intervention or a waitlist control condition (patients in the waitlist condition will receive the intervention after the intervention ends in the intervention group, i.e., after 6 months). The primary effect constitutes of the difference in change in pain coping between patients in the intervention and control condition from baseline to post-intervention. As secondary outcomes, a number of other psychological and physical outcome measures will be assessed (e.g., health-related quality of life, well-being, pain impact on daily life, pain cognitions). Also, cost-effectiveness of the intervention and the quality of the therapeutic relationship will be measured. conditions: Fibromyalgia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE maskingDescription: Blinding of participants and practitioners is not possible due to the nature of the study. However, the statistician who creates the randomization schedule and performs statistical analyses is blinded to group allocation. count: 70 type: ACTUAL name: Internet-based self-management intervention measure: Change in pain coping measure: Change in well-being measure: Change in illness cognitions measure: Change in pain coping strategies measure: Change in Illness Perceptions measure: Change in pain measure: Change in pain interference in daily functioning and pain severity, and as exploratory measures support, life control, and affective distress measure: Change in health-related quality of life measure: Change in fibromyalgia impact measure: Change in health-related quality of life measure: Economic evaluation: Five-Level Version of the EQ-5D (EQ-5D-5L) measure: Economic evaluation: iMTA Medical Consumption Questionnaire (iMCQ) measure: Economic evaluation: iMTA Productivity Cost Questionnaire (iPCQ) measure: Patient satisfaction measure: Expected/perceived patient-provider interaction sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fibrocentrum city: Leiden state: Zuid-Holland zip: 2321 GL country: Netherlands lat: 52.15833 lon: 4.49306 typeAbbrev: SAP hasProtocol: False hasSap: True hasIcf: False label: Statistical Analysis Plan date: 2022-07-25 uploadDate: 2023-11-27T05:27 filename: SAP_000.pdf size: 109827 hasResults: False
nctId: NCT06322472 id: 138956 briefTitle: The Relationship Between Phonological Awareness Skills And Home Environment Literacy in Cochlear Implant Users overallStatus: COMPLETED date: 2021-01-10 date: 2021-05-24 date: 2022-02-12 date: 2024-03-21 date: 2024-03-21 name: Uskudar University class: OTHER briefSummary: The aim was to examine the relationship between home literacy of parents whose has children who use cohlear implant and family demographic characteristics and phonological awareness skills of children with cochlear implant. conditions: Cochlear Implants conditions: Child Language conditions: Literacy conditions: Phonological (Speech) Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Descriptive research primaryPurpose: DIAGNOSTIC masking: NONE count: 46 type: ACTUAL name: The Turkish Early Language Development Test (TEDIL) name: The Family Literacy Scale name: The Early Childhood Phonological Sensitivity Scale (PASECP) name: The Early Literacy Home Environment Scale (ELHES) name: Demographic Questionaries measure: The data the Early Childhood Phonological Sensitivity Scale (PASECP) from children with cochlear implants measure: The data Family Literacy Scale from parents measure: The data Early Literacy Home Environment Scale (ELVES) from parents sex: ALL minimumAge: 5 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Uskudar University city: Istanbul country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06322459 id: Junlong Zhang briefTitle: Effect of Sport Education on Physical Fitness and Learning Attitude Among Junior High School Students overallStatus: RECRUITING date: 2024-02-25 date: 2024-06-29 date: 2024-07-05 date: 2024-03-21 date: 2024-03-21 name: Universiti Putra Malaysia class: OTHER briefSummary: Since the outbreak of COVID-19, students; sports environment and time have been severely compressed, which has had an unprecedented impact on their physical fitness and sports learning attitude. Therefore, it is urgent to adopt an effective teaching mode that aligns with curriculum reform to improve students; physical quality and learning attitude. The Sports Education Model is one of the most popular teaching models in Western developed countries, but the application in China and the related evidence of improving students; physical quality and learning attitude towards sports are relatively scarce. This study compares and analyzes the influence of the Sports Education Model and Traditional Teaching on junior middle school students; physical fitness and learning attitude, aiming to provide theoretical support for improving students; physical fitness and learning attitude and promoting the Sports Education Model in China. Promote the healthy development of junior middle school students. conditions: Physical Fitness studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Employing a Cluster randomized controlled experiment design, the experimental and control groups were randomly assigned to two different schools. Students participated in the Sport Education Model (experimental group) and traditional teaching (control group). primaryPurpose: BASIC_SCIENCE masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 78 type: ESTIMATED name: Sport Education Curriculum name: Normal teaching measure: Cardiovascular fitness test measure: Flexibility test measure: Speed test sex: ALL minimumAge: 13 Years maximumAge: 15 Years stdAges: CHILD facility: The 19th Middle School status: RECRUITING city: Qinhuangdao state: Hebei zip: 066000 country: China name: Junlong Zhang, PHD role: CONTACT phone: 0397698153 email: zhangjunlong2413@gmail.com name: Gege Yao, Master role: CONTACT name: Junlong Zhang role: PRINCIPAL_INVESTIGATOR lat: 39.93167 lon: 119.58833 hasResults: False
nctId: NCT06322433 id: 37C301 briefTitle: Follow up of High Myopic Eyes acronym: FWUPMIOPIA_ E overallStatus: RECRUITING date: 2023-11-01 date: 2024-11-01 date: 2025-11-01 date: 2024-03-21 date: 2024-03-21 name: Istituto Auxologico Italiano class: OTHER briefSummary: In this non-interventional retrospective and prospective observational study, the long-term evolution of clinical and iconographic characteristics of patients with pathological myopia will be considered Changes of some specific clinical, tomographic and angiographic variables evaluated on the baseline and after a minimum of 5 years follow-up will be studied. conditions: Pathologic Myopia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 138 type: ESTIMATED name: no drugs used for this study measure: Proportion of subjects with neovascularization at follow-up visit sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Istituto Auxologico Italiano IRCCS status: RECRUITING city: Milan zip: 20145 country: Italy name: Paolo Milani, MD role: CONTACT lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06322420 id: MoodHab briefTitle: Behavioral Activation for Depression and Habitual Rumination acronym: MoodHab overallStatus: RECRUITING date: 2024-02-09 date: 2025-07-01 date: 2026-02-01 date: 2024-03-21 date: 2024-03-21 name: Ragnar Pétur Ólafsson class: OTHER name: The Icelandic Centre for Research briefSummary: Depressive rumination, a negative thinking style characterized by repetitive and passive thoughts about the causes, meanings, and consequences of one's feelings and distress, is often described as being a habitual response tendency that forms a vulnerability to depression. Behavioural Activation (BA) is an effective treatment for depression but little is known of mechanisms of changes during a successful treatment completion and for whom the treatment benefits the most. The main purpose of the study is to investigate whether habit-like mood-reactive rumination will change during Behavioral Activation treatment for current depression and mediates symptom changes in the treatment. Important moderators of change will also be investigated (i.e. history of early life stress and cognitive flexibility). We aim to provide individual BA treatment for up to 130 currently depressed participants in 12 treatment sessions over 11 weeks. Measures are obtained at pre-treatment, during treatment, at post-treatment and at 6 month follow up. conditions: Major Depressive Disorder studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 130 type: ESTIMATED name: Behavioural Activation (BA) measure: Symptom severity measured by the BDI-2 measure: Disorder severity assessed with the DIAMOND diagnostic interview - Major Depressive Disorder measure: Diagnostic status assessed with the DIAMOND diagnostic interview - Major Depressive Episode measure: Symptom severity measured on the PHQ-9 measure: Momentary negative and positive affectivity using items from the PANAS (Positive and Negative Affect Schedule) measure: Diagnostic status assessed with the DIAMOND diagnostic interview at follow -up - Major Depressive Episode measure: Diagnostic status assessed with the DIAMOND diagnostic interview at follow-up- Major Depressive Disorder measure: The Quality of Life Scale (QOLS) measure: Generalized Anxiety Disorder-7 (GAD-7) measure: The Snaith-Hamilton Pleasure Scale (SHAPS) measure: Beck Anxiety Inventory (BAI) measure: The Ruminative Response Scale (RRS) measure: The Pearlin Mastery Scale (PMS) measure: The Environmental Reward Observation Scale (EROS) measure: Behavioral Activation for Depression Scale (BADS) sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Iceland status: RECRUITING city: Reykjavík zip: 102 country: Iceland name: Ragnar P Ólafsson, PhD role: CONTACT phone: 8622245 phoneExt: 00354 email: ragnarpo@hi.is name: Sigurður Viðar, Cand.Psych role: SUB_INVESTIGATOR name: Nína B Arnardóttir, MS role: SUB_INVESTIGATOR name: Ívar Snorrason, PhD role: SUB_INVESTIGATOR name: Igor Marchetti, PhD role: SUB_INVESTIGATOR lat: 64.13548 lon: -21.89541 hasResults: False