hackint0sh/New-Dataset huggingface dataset:
In order to further assess the wear of both restorative materials, full arch digital impressions (both upper and lower jaw) were taken at baseline evaluation and at every following evaluation using 3M True Definition Scanner. STL files were digitally compared to those taken at baseline. conditions: Tooth Wear conditions: Glass Ionomer Cements studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Blinded evaluation whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 39 type: ACTUAL name: Ketac Universal Aplicap Glass Ionomer Restorative (3M) (test group) name: Ketac Molar Quick Aplicap Glass Ionomer Restorative (control group) measure: Restoration survival over time based on the glass ionomer restoration criteria measure: Evaluation of restoration quality based on the glass ionomer restoration criteria measure: Evaluation of restoration wear based on comparison of digital impressions measure: Safety Endpoint: The safety endpoint is the incidence of Adverse Events. sex: ALL minimumAge: 18 Years maximumAge: 66 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Dental Health Clinic at Universidad Europea de Madrid (UEM) Department of Prosthodontics city: Madrid zip: 28045 country: Spain lat: 40.4165 lon: -3.70256 hasResults: False
nctId: NCT06275568 id: HSC-SPH-23-0655 briefTitle: Accelerating Healthcare Engagement in Healthy Food Interventions - Food Rx in High Risk Pregnant Mothers With About Fresh and Texas Children's Health Plan overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-11-15 date: 2024-11-15 date: 2024-02-23 date: 2024-02-23 name: The University of Texas Health Science Center, Houston class: OTHER briefSummary: The purpose of the study is to assess if the Fresh Connect food prescription (Fresh Connect Food Rx) program that provides consistent access to healthy fresh produce through purchases at the grocery store plus nutrition education impacts gestational weight gain, other pregnancy and birth outcomes, and food and nutrition security in low-income, ethnically diverse, at-risk women residing in Houston, Texas. Enrollment of participants will begin in pregnancy at the time of the first prenatal visit (as long as the first visit occurs before the end of the first trimester); each participant will be followed until 60 days post-partum (up to 11 months follow-up per participant). conditions: Nutrition in High-Risk Pregnancy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 620 type: ESTIMATED name: Usual Care Fresh Connect cardholder engagement name: Enhanced engagement communication measure: Absolute gestational weight gain (GWG) in pounds measure: Absolute gestational weight gain (GWG) in pounds measure: Absolute gestational weight gain (GWG) in pounds measure: Excess gestational weight gain (EGWG) in pounds measure: Excess gestational weight gain (EGWG) in pounds measure: Excess gestational weight gain (EGWG) in pounds measure: Number of participants diagnosed with pregnancy-induced hypertension measure: Number of participants diagnosed with gestational diabetes measure: Number of participants with pre-term birth (<37 weeks) measure: Infant birth weight sex: FEMALE minimumAge: 18 Years maximumAge: 44 Years stdAges: ADULT facility: The University of Texas Health Science Center at Houston city: Houston state: Texas zip: 77030 country: United States name: Shreela Sharma, PhD role: CONTACT phone: 713-500-9344 email: Shreela.V.Sharma@uth.tmc.edu name: Naomi Tice, MPH role: CONTACT phone: (713) 500-9000 email: Naomi.Tice@uth.tmc.edu lat: 29.76328 lon: -95.36327 hasResults: False
nctId: NCT06275555 id: 2023-101 briefTitle: Use of Bivalirudin for Anticoagulation in Patients With Extracorporeal Membrane Oxygenation overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-12-31 date: 2024-02-23 date: 2024-02-26 name: Xiaotong Hou class: OTHER briefSummary: The purpose of this study was to evaluate the efficacy and safety of bivalirudin in anticoagulation therapy in patients with extracorporeal membrane oxygenation (ECMO) compared with unfractionated heparin. conditions: Extracorporeal Membrane Oxygenation Complication studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 154 type: ESTIMATED name: bivalirudin name: unfractionated heparin measure: thrombotic complications measure: bleeding complications measure: Hospitalization mortality measure: Loop replacement measure: Infusion volume of blood products measure: Acute renal failure measure: Heparin-induced thrombocytopenia measure: the time of reaching the target anticoagulant level for the first time measure: Percentage of time during ECMO within the target anticoagulant level sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Beijing Anzhen Hospital city: Beijing state: Beijing zip: 100029 country: China lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06275542 id: USurabaya briefTitle: Ability to Maintain Saturation Levels Without Oxygen Supplementation as a Extubation Criteria Without TOF Monitoring Equipment overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-12-01 date: 2026-01-01 date: 2024-02-23 date: 2024-02-23 name: University of Surabaya class: OTHER name: Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Gadjah Mada name: Sardjito General Hospital, Yogyakarta briefSummary: Patients undergoing general anesthesia will have an endotracheal tube inserted. Adequate muscle strength recovery in the recovery room is crucial to ensure before extubation. One of the criteria we use to determine the recovery of muscle strength post-use of muscle relaxants in conditions without specific monitoring devices is the ability to maintain body oxygen levels without oxygen assistance for 3 minutes. This study aims to determine the muscle strength value in the recovery room using extubation strategies without muscle strength monitoring compared to extubation strategies with muscle strength monitoring. conditions: Anesthesia Intubation Complication studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The study was conducted through a randomized clinical trial with blinding of observers. Two parallel groups were selected to compare the incidence of paralysis in the recovery room. The research samples were collected using non-probability sampling method through consecutive enrollment over a specific period. This study consisted of 3 comparisons distinguished based on the type of volatile anesthetic gas maintenance and neuromuscular blockade agent, namely:
* Comparison 3: The volatile anesthetic gas used was sevoflurane and the muscular blockade agent used was atracurium. primaryPurpose: PREVENTION masking: DOUBLE maskingDescription: Upon arrival in the recovery room, all subjects were fitted with SpO2, EKG, NIBP monitors, and the TOF monitoring device. TOF values were measured by a second researcher who was unaware of the type of intervention. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 240 type: ESTIMATED name: Train of four monitoring device intraoperative name: Neostigmine name: Air chalenge prior to extubation name: Train of Four monitoring device in recovery room measure: Residual paralysis in recovery room measure: Adverse events sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT hasResults: False
nctId: NCT06275529 id: 27.12.2023.685 briefTitle: Evaluation of Transforaminal Epidural Steroid Injection in Radicular Low Back Pain According to MSU Classification overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2024-06-15 date: 2024-08-15 date: 2024-02-23 date: 2024-02-23 name: Başakşehir Çam & Sakura City Hospital class: OTHER_GOV briefSummary: Low back pain is a common disease in all ages and it effects seriously quality of life. Medical treatment,interventional methods and surgery are the treatment options. Transforaminal epidural steroid injections (TFSI) is one of the interventional method for radiculopathy with low back pain. Michigan State University(MSU) classification is a MRI based disc herniation classification. It helps to classified disc herniation in types, places and sizes.
The aim of this study to evaluate the pain and oswestry disability index in patients who have radiculopathy with low back pain, undergone TFSI according to MSU classification. conditions: Radiculopathy Lumbar conditions: Low Back Pain conditions: Disc Herniation conditions: Injections, Epidural studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 160 type: ESTIMATED name: Transforaminal Epidural Steroid Injection measure: Change of the pain severity score measure: Change of the disability score sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06275516 id: 2024-208 briefTitle: Safety and Efficacy of Multisensory Stimulation Virtual Reality for Stroke Patients. overallStatus: NOT_YET_RECRUITING date: 2024-02-20 date: 2024-06-20 date: 2024-09-20 date: 2024-02-23 date: 2024-02-23 name: First Affiliated Hospital of Chongqing Medical University class: OTHER briefSummary: This was a single-blind randomized controlled trial of multisensory stimulation virtual reality to improve motor and cognitive dysfunction in stroke patients. conditions: Stroke studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: multi-sensory stimulation immersive VR+ treadmill training name: treadmill training measure: Fugl-Meyer scale measure: Berg balance scale measure: three-dimensional gait detection measure: Fall incidents measure: Dizzy incidents sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06275503 id: STROKESTOP III briefTitle: STROKESTOP III - Optimized Method for Atrial Fibrillation Screening overallStatus: NOT_YET_RECRUITING date: 2024-02-20 date: 2025-02-28 date: 2026-06-30 date: 2024-02-23 date: 2024-02-23 name: Danderyd Hospital class: OTHER name: Karolinska Institutet name: Landstinget i Värmland briefSummary: Atrial fibrillation is the most common sustained cardiac arrhythmia affecting more than 3% of the adult population. The symptoms of atrial fibrillation can range from asymptomatic to debilitating. It can be permanent in its nature, but also paroxysmal with only short bursts of atrial fibrillation randomly occurring and can therefore remain unnoticed. Atrial fibrillation increases the risk of stroke five fold if left untreated.
Opportunistic screening has shown promising results with higher participation rates and the possibility of better outreach. There is a lack of data from randomized trials on the difference in participation rates in systematic and opportunistic screening approaches when screening with prolonged ECG monitoring. conditions: Atrial Fibrillation conditions: Atrial Fibrillation New Onset studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Cluster randomized trial primaryPurpose: SCREENING masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 2200 type: ESTIMATED name: Screening invitation mode measure: Participation in screening measure: AF detection in opportunistic compared to systematic screening measure: OAC treatment after AF detection measure: Compliance to OAC treatment 1 year after initiation measure: Health economy measure: Composite endpoint of stroke, death and severe bleeding measure: Reminder strategy effect on participation measure: Comparison of automatic ECG analysis (using AI) for detection of AF in a (by AI algorithm classified) high- compared to a low-risk group measure: Application of the FIND-AF algorithm sex: ALL minimumAge: 75 Years maximumAge: 76 Years stdAges: OLDER_ADULT facility: Karolinska Institutet, Dept Med H city: Stockholm zip: 141 86 country: Sweden name: Emma Svennberg, MD PhD role: CONTACT phone: +46739584822 email: emma.svennberg@regionstockholm.se name: MD PhD role: CONTACT lat: 59.33258 lon: 18.0649 facility: Region Värmland city: Värmland country: Sweden name: Fredrik Carlstedt role: CONTACT lat: 60.83333 lon: 16.5 hasResults: False
nctId: NCT06275490 id: 181123PER6_3_1 briefTitle: Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus L- PRF Block overallStatus: RECRUITING date: 2024-01-01 date: 2024-05-01 date: 2024-11-15 date: 2024-02-23 date: 2024-02-23 name: Cairo University class: OTHER briefSummary: * The aim is to evaluate post extraction hard tissue changes following ridge preservation using partially demineralized dentin block versus L-PRF block in intact socket in the esthetic zone.
* In intervention group: the teeth will be cleaned and dried, and then the dentin will be ground to obtain particles of a certain size then partially demineralize dentin will obtained by using a tooth transformer machine. At the same time, blood samples are collected and processed to obtain fibrin membranes rich in platelets and leukocytes. This tissue is then mixed with partially demineralized dentin to create a solid mass called a "dentin block". During the process of preserving the alveolar bumps after extraction, this solid mass "dentin mass" is placed inside the dental pockets and covered with fibrin membranes rich in platelets and white blood cells, then 5/0 proline suture are used to fix the fibrin membranes and dentin mass in place. After the recovery period "4-6 months", a biopsy is taken for some cases from the site of the operation for histological evaluation during implant placement.
* Outcomes: Radiographic vertical buccal bone changes, vertical Palatal bone changes, horizontal bone changes, Percentage of new vital bone formation, Percentage of residual bone graft, Implant Primary Stability. The results directly postoperative and 4-6 months postoperatively. conditions: Socket Preservation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A Randomized Controlled Pilot Trial primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 20 type: ESTIMATED name: Partially Demineralized Dentin Block name: L-PRF block measure: Radiographic vertical bone changes measure: Radiographic horizontal bone changes measure: Percentage of new vital bone formation and residual graft measure: Implant Primary Stability sex: ALL minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Faculty of dentistry Cairo University status: RECRUITING city: Cairo state: Elmanil zip: 4240101 country: Egypt lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06275464 id: BT-600-101 briefTitle: BT-600 Single and Multiple Ascending Oral Doses in Healthy Adult Subjects overallStatus: RECRUITING date: 2024-01-11 date: 2024-04 date: 2024-06 date: 2024-02-23 date: 2024-02-23 name: Biora Therapeutics, Inc. class: INDUSTRY briefSummary: This is a randomized, double-blind, placebo-controlled Phase 1 study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of BT-600 when administered in single and multiple ascending doses to healthy participants. The study will enroll up to 48 participants, with participation lasting 2-3 weeks in addition to up to 28 days (about 4 weeks) for screening.
BT-600 is a swallowable drug/device combination product designed to deliver a liquid formulation of tofacitinib to the colon and dispense the study drug throughout the colon. BT-600 consists of two components, the drug part containing a reservoir, which will be filled with liquid tofacitinib, and the drive part. The drive part contains the hardware and software that identifies the colon region and then dispenses the drug to the specific region. The device which contains the drug is referred to as the NaviCap™ device. The NaviCap device is approximately the size of a fish oil pill, is made of plastic material known to be safe for ingestion and has rounded ends for ease of swallowing. Liquid tofacitinib in the reservoir is automatically released when the BT-600 localization technology determines that it has reached the colon. BT-600 passes through the colon and the NaviCap device is excreted via a bowel movement. conditions: Healthy studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 48 type: ESTIMATED name: BT-600 name: BT-600 Placebo measure: Adverse Events measure: Pharmacokinetic (PK) Assessments sex: ALL minimumAge: 19 Years maximumAge: 50 Years stdAges: ADULT facility: Celerion status: RECRUITING city: Lincoln state: Nebraska zip: 68502 country: United States lat: 40.8 lon: -96.66696 hasResults: False
nctId: NCT06275451 id: EssaiClinique_QUALI-RES briefTitle: Qualitative Study of Emotional Regulation in Schizophrenia acronym: QUALI-RES overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2025-01 date: 2026-01 date: 2024-02-23 date: 2024-02-28 name: University Hospital, Grenoble class: OTHER briefSummary: The main aim of this study is to investigate emotional regulation in individuals with schizophrenia using a qualitative methodology (semi-structured interview) and, therefore, from the person's point of view.
Given the qualitative nature of the methodology used in this study, the investigators have no specific hypothesis. The investigators have a general hypothesis suggesting that the patients' discourse will enable us to highlight the emotional regulation difficulties described in the literature. conditions: Schizophrenia conditions: Schizophrenia Schizoaffective studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 40 type: ESTIMATED name: Semi-structured interview measure: Emotional regulation in schizophrenia measure: Factors influencing emotional regulation in schizophrenia measure: Improved emotional regulation in schizophrenia measure: Stages of emotional regulation in schizophrenia sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT hasResults: False
nctId: NCT06275438 id: 81829502.903/39 briefTitle: Comparison of Oxytocin Receptor Immunoreactivity in Placentas Obtained From Women Having Cesarean and Natural Birth overallStatus: COMPLETED date: 2018-08-25 date: 2019-07-01 date: 2019-12-01 date: 2024-02-23 date: 2024-02-23 name: Kafkas University class: OTHER briefSummary: Our study examines the effects of oxytocin hormone receptors. mechanisms of placental tissue cells and therefore intrauterine development. It was conducted to investigate the effects on newborn babies apgar score, fontanel openings, birth weights, etc. By collecting data, normal and They were compared between cesarean births by statistical analysis. normal in this regard Based on the hypothesis that there is a difference between labor and cesarean delivery, this study has been made.OXTR primary antibody was used for immunohistochemical examination. There was no significant difference between the groups in terms of histological examination. In the study, it was found that OXTR immunoreactivity was strong in decidual cells and stromal cells in villi. A stronger OXTR immunoreactivity was detected in villous stroma of placenta of the natural birth group compared to the cesarean birth group. Reaction was not observed in syncytotrophoblast cells and syncytial nodes in both groups, but strong immunoreaction was observed fetal endothelial cells and fetal capillaries in both groups. conditions: Healthy Mothers Who Have Had Both Vaginal and Cesarean Deliveries studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: "Our study was conducted on the placentas of 40 women admitted to the obstetrics clinics of Kars Harakani State Hospital and Kafkas University Training and Research Hospital, after obtaining necessary permissions. Out of 40 placentas, 5 were excluded due to blood incompatibility, 2 were excluded due to subsequent diagnosis of chronic conditions (thyroid disorder, Behçet's disease), and 1 was excluded due to the presence of an accessory placenta, resulting in a total of 32 placentas included in the study. Among these, 16 were from women who had undergone normal vaginal delivery (control group), and 16 were from women who had undergone cesarean section (case group). Tissue samples obtained from the placentas were subjected to histological and immunohistochemical methods to obtain various findings primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 32 type: ACTUAL name: The delivery being performed via cesarean section surgery rather than natural childbirth measure: Oksitosin Receptor Immunoreactivity measure: Pearson correlation analysis sex: FEMALE minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: Kafkas Universty city: Kars state: Merkez zip: 36100 country: Turkey lat: 40.59825 lon: 43.08548 hasResults: False
nctId: NCT06275425 id: 4-2023-0429 briefTitle: Comparison of the Coughing Frequency of Remimazolam Total Intravenous Anesthesia Versus Inhalational Anesthesia overallStatus: COMPLETED date: 2023-06-25 date: 2023-11-29 date: 2023-11-29 date: 2024-02-23 date: 2024-02-23 name: Yonsei University class: OTHER briefSummary: This study is a randomized controlled trial. Adult patients undergoing thyroidectomy under general anesthesia at Severance Hospital and Yonsei Cancer Center are included in tis study. For intervention group, patients receive anesthesia with total intravenous remimazolam, while for control group, patients receive anesthesia with inhalation anesthetic.
The primary end point of the study is to determine whether coughing during endotracheal tube extubation is less when anesthesia is maintained with intravenous remimazolam compared to inhalation anesthetics. The secondary end points are cough score (graded into 4 levels), frequency of reoperation due to postoperative bleeding, These include the frequency of hypertension during the extubation process and whether additional painkillers are used in the recovery room. conditions: Thyroid Neoplasm conditions: Cough studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: a single-blinded randomized controlled trial primaryPurpose: PREVENTION masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 106 type: ACTUAL name: Total intravenous anesthesia with Byfavo name: Inhalation anesthesia with Sevoflurane measure: Proportion of patients not coughing during postoperative extubation measure: Cough score sex: ALL minimumAge: 19 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, College of Medicine, Yonsei University, city: Seoul country: Korea, Republic of lat: 37.566 lon: 126.9784 hasResults: False