hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06261775 id: IRB-2401011-EXM briefTitle: Effect of Minimally Processed Animal Protein on Biomarkers for Cognitive Decline overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-30 date: 2024-02-07 date: 2026-01-02 date: 2024-02-15 date: 2024-02-22 name: South Dakota State University class: OTHER briefSummary: Minimally processed animal protein is a premier source of essential macro and micronutrients in the diet and is important, especially to older adults who are at increased risk of nutritional deficiency and age-related physiological changes. Our central hypothesis is that adding lean animal protein within a dietary guideline-based diet will enhance nutrient adequacy and attenuate markers of cognitive decline. This is a retrospective study leveraging samples collected from the feeding trial NCT05581953. PI for both studies are the same. conditions: Healthy Lifestyle studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: OTHER masking: NONE count: 36 type: ACTUAL name: Red meat-based meal name: Lacto-ovo-vegetarian meal measure: Concentration of phosphatidylcholine in blood sex: ALL minimumAge: 65 Years stdAges: OLDER_ADULT facility: South Dakota State University, Wagner Hall 416 city: Brookings state: South Dakota zip: 57007 country: United States lat: 44.31136 lon: -96.79839 hasResults: False
nctId: NCT06261762 id: SDC-24-1 briefTitle: Hard and Soft Tissue Dimensional Change After Consecutive Extractions and Unassisted Socket Healing in the Esthetic Zone overallStatus: NOT_YET_RECRUITING date: 2024-02-29 date: 2026-06-30 date: 2026-06-30 date: 2024-02-15 date: 2024-02-15 name: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University class: OTHER briefSummary: The goal of this observational study is to evaluate the post-extraction hard and soft tissue dimension changes in patients requiring consecutive extractions and unassisted socket healing in the anterior maxilla. The main questions it aims to answer are:
Participants will undergo consecutive (two) extractions and will be evaluated after subsequent unassisted socket healing for 8 weeks. conditions: Wound Heal studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 20 type: ESTIMATED measure: Bone level change from baseline measure: Soft tissue change from baseline measure: Correlation between baseline facial bone thickness and dimensional soft tissue alterations during healing at the interalveolar septum. sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06261749 id: EmgSCAPULA briefTitle: Analysis of Scapular Musculature Activation During Targeted Abdominal Contraction With Scapular Stabilization Exercises overallStatus: RECRUITING date: 2024-02-15 date: 2024-04 date: 2024-08 date: 2024-02-15 date: 2024-02-28 name: Hacettepe University class: OTHER briefSummary: Muscle activation of the upper trapezius, lower trapezius and serratus anterior muscles will be measured during prone scapular retraction exercises. Then the same exercises will be performed with abdominal contraction using a stabilizer and muscle activity of the same muscles will be measured. A comparison will be made between the two conditions. conditions: Scapula; Increased studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30 type: ESTIMATED name: Voluntary Abdominal Contractions name: Exercise measure: Electromyography sex: ALL minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT facility: Hacettepe University status: RECRUITING city: Ankara zip: 06100 country: Turkey name: İrem Düzgün, Prof role: CONTACT phone: +903051577 email: iremduzgun@yahoo.com lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06261736 id: 2107044-1 briefTitle: The Effectiveness of Prophylactic Antibiotics for Urethral Bulking overallStatus: RECRUITING date: 2023-10-24 date: 2025-05 date: 2025-05 date: 2024-02-15 date: 2024-02-15 name: Atlantic Health System class: OTHER briefSummary: The goal of this clinical trial is to evaluate if prophylactic antibiotics in urethral bulking are effective in reducing postprocedural urinary tract infections. conditions: Stress Urinary Incontinence conditions: Postoperative Urinary Tract Infection conditions: Urethral Bulking studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 70 type: ESTIMATED name: Prophylactic antibiotics name: No antibiotics measure: Rate of urinary tract infection (UTI) measure: Rate of postoperative urinary retention measure: Rates of other postoperative complications sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Atlantic Health status: RECRUITING city: Morristown state: New Jersey zip: 07960 country: United States name: Tess Gao, MD role: CONTACT phone: 973-971-7267 email: tess.gao@atlantichealth.org name: Erika Wasenda, MD role: PRINCIPAL_INVESTIGATOR lat: 40.79677 lon: -74.48154 hasResults: False
nctId: NCT06261723 id: PI22/1009 briefTitle: Effect of Non-chirurgical Periodontal Treatment on the Immune System From a Gender Perspective overallStatus: RECRUITING date: 2024-02-15 date: 2025-09-01 date: 2025-12-31 date: 2024-02-15 date: 2024-04-16 name: Milagros Rocha Barajas class: OTHER name: Instituto de Salud Carlos III briefSummary: The goal of this observational study is to evaluate non-surgical periodontal treatment in women and men with periodontitis with and without obesity. The main questions it aims to answer are:
Obese or non-obese participants with periodontitis will receive non-surgical periodontal treatment, consisting of oral health guidance and mechanical periodontal debridement throughout the mouth using an ultrasonic device and manual curettes. Researchers will compare four groups: obese women, non-obese women, obese men, and non-obese men, to clarify the involment of immune response after treatment, considering the coexistence of obesity and potential gender differences. conditions: Periodontal Diseases studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: CROSS_SECTIONAL count: 100 type: ESTIMATED name: non-chirurgical periodontal treatment measure: Changes in inflammasome complex activation grade in patients with chronic periodontitis with and without obesity, before and after non-surgical periodontal treatment. measure: Changes in endothelial function in the study population. measure: Changes in endothelial function at molecular level in the study population. measure: Changes in the systemic inflammation status in the study population. measure: Changes in the expression of genes related to inflammatory pathways in PBMC in the study population. measure: Changes in the expression of genes related to oxidative stress levels in PBMC in the study population. measure: Changes in the expression of genes related to cellular respiration in PBMC in the study population. measure: Sequence miRNAs in biological fluids in patients with chronic periodontitis with and without obesity, before and after non-surgical periodontal treatment. measure: Evaluate the distribution and phenotype of different T lymphocyte and monocyte subpopulations in the study population. measure: Changes in the protein expression of autophagy markers in PBMC in the study population. measure: Evaluate autophagy flux in the study population. measure: Evaluate autophagosome formation in the study population. sex: ALL minimumAge: 18 Years maximumAge: 69 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University Hospital Dr Peset status: RECRUITING city: Valencia zip: 46017 country: Spain name: Milagros Rocha Barajas, PhD role: CONTACT phone: 0034 963 189 132 email: milagros.rocha@fisabio.es name: Milagros Rocha Barajas, PhD role: PRINCIPAL_INVESTIGATOR lat: 39.46975 lon: -0.37739 facility: University Hospital Dr. Peset status: RECRUITING city: Valencia zip: 46017 country: Spain name: Milagros Rocha Barajas role: CONTACT phone: 963188875 email: milagros.rocha@fisabio.es lat: 39.46975 lon: -0.37739 hasResults: False
nctId: NCT06261710 id: EA2_253_23 briefTitle: Intrapartum Ultrasound in Labor: Sonography Only, Few Internal Examinations acronym: SOFIE overallStatus: RECRUITING date: 2024-02-27 date: 2029-02-01 date: 2030-02-01 date: 2024-02-15 date: 2024-02-16 name: Larry Hinkson class: OTHER briefSummary: This is a prospective, randomized trial to determine whether the use of sonographic parameters during labor results in less intrapartum infection compared to traditional invasive examination. Other secondary outcomes include maternal satisfaction and overall birth outcomes. conditions: Labor Complication studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 356 type: ESTIMATED name: Sonography in labour measure: Maternal Fever Incidence measure: Maternal Tachycardia Incidence measure: Maternal Leucocytosis measure: Uterine tenderness measure: Fetal Tachycardia measure: Foul-smelling amniotic fluid measure: Average age measure: Maternal weight measure: Maternal height measure: Completed weeks of pregnancy measure: Previous pregnancy measure: Incidence of Vaginal Examinations measure: Incidence of Caesarean section measure: Incidence of Instrumental Delivery measure: Incidence of estimated blood loss >1000 ml measure: Incidence of antibiotics usage measure: Incidence of Neonatal Admission measure: Neonatal weight measure: Maternal Satisfaction Scores measure: Incidence of Chorioamnionitis on Placenta Histologie sex: FEMALE minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Charité University Hospital status: RECRUITING city: Berlin country: Germany name: Larry Hinkson, FRCOG role: CONTACT lat: 52.52437 lon: 13.41053 hasResults: False
nctId: NCT06261697 id: P.T.REC/012/004876 briefTitle: Relationship Between Smartphone Addiction and Temporomandibular Joint Disorders Among Adults in Egypt. overallStatus: NOT_YET_RECRUITING date: 2024-02-20 date: 2024-04 date: 2024-06 date: 2024-02-15 date: 2024-02-21 name: Cairo University class: OTHER briefSummary: Cross sectional study to investigate the relation between Smartphone addiction and temporomandibular disorders among youth population in Egypt. An online- based questionnaire study. A 296 participants who are Egyptians with age between18 and 35 years old without prior neck and upper extremity related diseases, orofacial trauma or surgeries, history of rheumatoid arthritis or congenital musculoskeletal problems. An online- based questionnaire will be sent through different social media platforms, it will include three screens, the first includes the consent form, the second includes the demographic data (year of birth, current educational status, gender and geographic information ), and the third page includes questionnaires
. conditions: Temporomandibular Disorders conditions: Smartphone Addiction studyType: OBSERVATIONAL observationalModel: CASE_CROSSOVER timePerspective: PROSPECTIVE count: 296 type: ESTIMATED name: A web based survey measure: Fonseca Anamnestic Index (FAI) questionnaire measure: Smartphone Addiction Scale-Short version (SAS-SV) questionnaire measure: Patient Health Questionnaire (PHQ) sex: ALL minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT hasResults: False
nctId: NCT06261684 id: MS-259-2023 briefTitle: Intralesional Acyclovir Versus Cryotherapy in the Treatment of Plantar Warts. A Randomized Controlled Trial. overallStatus: RECRUITING date: 2023-10-01 date: 2024-10-01 date: 2024-10-01 date: 2024-02-15 date: 2024-02-15 name: Cairo University class: OTHER briefSummary: The goal of this prospective randomized controlled study is to study the safety and efficacy of intralesional acyclovir compared to cryotherapy in plantar warts. The main questions needed to be answered are:
2. Is Intralesional acyclovir more efficient in treating plantar warts compared to cryotherapy? conditions: Plantar Wart studyType: INTERVENTIONAL phases: PHASE2 phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 92 type: ESTIMATED name: Intralesional Acyclovir name: Cryotherapy measure: Cure rate measure: Recurrence rate measure: Patient satisfaction score measure: Correlation of treatment with number of ipsilateral warts measure: Correlation of treatment with age measure: Correlation of treatment with gender measure: Correlation of treatment with size of the wart sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Cairo University Hospital status: RECRUITING city: Cairo country: Egypt name: Basant Helal, MRCP role: CONTACT name: Shahira Ramadan, Professor role: PRINCIPAL_INVESTIGATOR name: Yousra Azzazi, Lecturer role: SUB_INVESTIGATOR lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06261671 id: 2312-ABU-028-VF briefTitle: Effect of Antioxydant-enriched Media on Blastocyst Euploidy Rates. acronym: GX overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-12-31 date: 2024-12-31 date: 2024-02-15 date: 2024-02-15 name: ART Fertility Clinics LLC class: OTHER briefSummary: One of the most sensible factors in IVF culture conditions is the susceptibility of gametes and embryos to an induced increase in reactive oxidative species (ROS) caused by the artificial environment. This study aims to evaluate the impact of using antioxidant-supplemented media during culture to evaluate embryo ploidy rates in a prospective randomized trial using sibling oocytes. conditions: Infertility conditions: In Vitro Fertilization studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A randomization list (indicating Gx Media Vitrolife or GT Coopersurgical) will be used to verify to which group the first half of oocytes will be allocated to. In case an odd number of oocytes is present, one extra oocyte is allocated to the group as indicated by the randomization list. primaryPurpose: TREATMENT masking: NONE count: 500 type: ESTIMATED name: antioxidants-enriched culture medium (Gx) measure: Blastocyst ploidy is determined after a biopsy of trophectoderm cells, taken from the blastocyst on day 5, 6 or 7 from development. The following outcomes are possible: • Normal • Abnormal • No result/Inconclusive • Low or high Mosaic measure: Cycle ploidy rate: the number of euploid embryos in the group Blastocyst quality at the time of biopsy based on modified Gardner's criteria. Usable blastocyst rate per group and per day of biopsy (day 5, 6, 7) sex: ALL minimumAge: 18 Years maximumAge: 43 Years stdAges: ADULT hasResults: False
nctId: NCT06261658 id: TESOVA2022 briefTitle: Improving the Quality of Cryopreserved Ovarian Tissue Reimplantation Using Platelet-enriched Autologous Plasma acronym: TESOVA2022 overallStatus: RECRUITING date: 2024-03-01 date: 2024-12-29 date: 2033-12-29 date: 2024-02-15 date: 2024-02-15 name: IRCCS Azienda Ospedaliero-Universitaria di Bologna class: OTHER briefSummary: The study is aimed to evaluate the effects of intraovarian injection of autologous Platelet-enriched Autologous Plasma on the outcomes of orthotopic transplantation of cryopreserved ovarian tissue. conditions: Cryopreservation conditions: Ovary Injury conditions: Infertility, Female conditions: Menopause Ovarian Failure studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 45 type: ESTIMATED name: Cryopreserved Ovarian Tissue Reimplantation measure: Safety of Cryopreserved ovarian tissue transplantation Using Platelet-enriched Autologous Plasma measure: Effectiveness of Cryopreserved ovarian tissue transplantation Using Platelet-enriched Autologous Plasma sex: FEMALE stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Diego Raimondo status: RECRUITING city: Bologna state: BO zip: 40138 country: Italy name: Diego Raimondo, MD role: CONTACT phone: 0512144389 phoneExt: 0039 email: die.raimondo@gmail.com name: Renato Seracchioli, MD role: PRINCIPAL_INVESTIGATOR name: Diego Raimondo, MD role: SUB_INVESTIGATOR name: Rossella Vicenti, PhD role: SUB_INVESTIGATOR name: Valentina Magnani, PhD role: SUB_INVESTIGATOR lat: 44.49381 lon: 11.33875 hasResults: False
nctId: NCT06261645 id: ROTOFUNK_2_2023 briefTitle: Rotofunc - Non-traumatic Shoulder Instability and Total Rotator Cuff Function acronym: ROTOFUNC overallStatus: RECRUITING date: 2023-05-01 date: 2025-12 date: 2026-12 date: 2024-02-15 date: 2024-03-08 name: Sahlgrenska University Hospital, Sweden class: OTHER briefSummary: The goal of this clinical trial is to test the effect of a novel assessment and treatment strategy for young adults with severely disabling non-traumatic shoulder instability. The main question it aims to answer is if this treatment will substantially change the patients shoulder function to a more stable and controllable state and thereby give a higher quality of life. Participants failure in active shoulder muscle function will be assessed and exercises will be selected individually. Patients will be asked to perform the exercises twice per day. At clinical visits to a specialized physiotherapist the exercises will be upgraded to restore full dynamic stability throughout shoulder movement range. The active treatment period will be 4 months. Researchers will compare two groups. One group will start directly after a baseline assessment is fulfilled. The other group will receive the treatment with a delay of 4 months to evaluate if the selected exercises can substantially change the shoulder stability compared to no treatment, the natural course of the condition. conditions: Shoulder Dislocation or Subluxation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: A 16 week exercise program with specific exercises to restore total rotator cuff function individually selected during clinical physiotherapy visits and performed 2 - 4 times daily.
Individuals are not identifiable. The outcome assessor are planning for all statistics used and is not in other ways involved in the study. whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 100 type: ESTIMATED name: Early Physiotherapist selected active exercises name: Delayed Physiotherapist selected active exercises measure: Neuromuscular control measure: Clinical assessment - Active and passive range of motion measure: Pain at rest measure: Pain during motion measure: Apprehension of instability during motion measure: Patient reported quality-of-life in relation to shoulder function measure: Patient's satisfaction sex: ALL minimumAge: 16 Years maximumAge: 35 Years stdAges: CHILD stdAges: ADULT facility: Sahlgrenska University Hospital/Mölndal, Physiotherapy Dpt status: RECRUITING city: Gothenburg state: Mölndal zip: SE 43180 country: Sweden name: Ingrid K Hultenheim Klintberg, PhD role: CONTACT email: ingrid.hultenheim-klintberg@vgregion.se lat: 57.70716 lon: 11.96679 hasResults: False
nctId: NCT06261632 id: Hemo-Blood briefTitle: Blood Flow Restriction in Improving Muscle Strength of Patients With Hemophilic Knee Arthropathy overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-19 date: 2024-07-28 date: 2024-11-01 date: 2024-02-15 date: 2024-02-20 name: Investigación en Hemofilia y Fisioterapia class: NETWORK briefSummary: Background. The main physical sequela of patients with hemophilia is the development of a progressive, degenerative intra-articular lesion, known as hemophilic arthropathy). This sequela is manifested by chronic pain, limited range of motion, axial abnormalities, and periarticular muscle atrophy.
Study design. Randomized, multicenter, single-blind clinical study. Method. 60 patients with hemophilia A and B will be recruited in this study. Patients will be recruited in 6 regions of Spain. The dependent variables will be: bleeding frequency (self-registration), pain (measured with the visual analog scale and pressure algometer), quality of life (SF-36 scale), joint status (Hemophilia Joint Health Score scale), strength (dynamometer) and muscle activation (surface electromyograph), range of motion (goniometer) and functionality (Timed up and go test). Three evaluations will be carried out: pre-treatment, post-treatment and after a follow-up period of 4 weeks.
Expected results. Observe the safety of blood flow restriction in hemophilia patients. To analyze the efficacy of blood flow restriction in improving muscle strength and activation, range of motion, chronic pain, functionality, and the perception of quality of life in patients with hemophilic knee and ankle arthropathy. conditions: Hemophilia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: Blood flow restriction measure: Change from baseline hemarthrosis after treatment and at four weeks measure: Change from baseline pressure pain threshold after treatment and at four weeks measure: Change from baseline muscle strength after treatment and at four weeks measure: Change from baseline electrical activity of the muscles after treatment and at four weeks measure: Change from baseline range of motion after treatment and at four weeks measure: Change from baseline joint status after treatment and at four weeks measure: Change from baseline functionality after treatment and at four weeks sex: MALE minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: University of Oviedo city: Oviedo state: Asturias zip: 33006 country: Spain lat: 43.36029 lon: -5.84476 hasResults: False
nctId: NCT06261619 id: 2079951 briefTitle: Superiority Trial Between Sotair® Device Attached to Manual Resuscitator Versus Ventilation Alone overallStatus: RECRUITING date: 2024-02-19 date: 2025-01-31 date: 2025-06-01 date: 2024-02-15 date: 2024-02-20 name: Rhode Island Hospital class: OTHER briefSummary: Effective respiratory ventilation is achieved by moving the right amount of air to and out of the lungs while keeping the pressures at a safe level. A disposable safety device, Adult Sotair®, was created to improve manual ventilation delivery. In this superiority study, the investigators will perform two-group cross over randomized design to test the superiority of the Adult Sotair® device compared to manual ventilation alone. conditions: Airway Management conditions: Respiration, Artificial studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Study Design: A superiority trial; a single two-group cross over randomized trial. primaryPurpose: SUPPORTIVE_CARE masking: SINGLE maskingDescription: The care provider will not know the recorded lung function recordings. whoMasked: PARTICIPANT count: 30 type: ESTIMATED name: Adult Sotair Device measure: Peak airway pressure measure: Tidal volume measure: Airflow sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Rhode Island Hospital status: RECRUITING city: Providence state: Rhode Island zip: 02903 country: United States name: Mark Kendall, MD role: CONTACT phone: 401-444-5172 email: mark.kendall@lifespan.org lat: 41.82399 lon: -71.41283 hasResults: False