hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06321042 id: SYMPHO-EM briefTitle: Evaluation of the Clinical Outcomes of the Total Knee ps Prosthesis Implanted With the Use of Inertial Sensors acronym: SYMPHO-EM overallStatus: RECRUITING date: 2023-01-13 date: 2027-01 date: 2027-03 date: 2024-03-20 date: 2024-03-20 name: Istituto Ortopedico Rizzoli class: OTHER briefSummary: evaluate the clinical outcome of the implantation of a specific primary TKA model implanted with the aid of inertial sensors for the execution of bone cuts through the administration of questionnaires for the calculation of clinical-functional scores; conditions: Prosthesis Durability studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 40 type: ESTIMATED name: Knee arthroplasty measure: Knee Society Score measure: Knee Society Score measure: Knee Society Score measure: Knee Society Score measure: Western Ontario and McMaster Universities Arthritis Index measure: Western Ontario and McMaster Universities Arthritis Index measure: Western Ontario and McMaster Universities Arthritis Index measure: Western Ontario and McMaster Universities Arthritis Index measure: Knee injury and Osteoarthritis Outcome Score measure: Knee injury and Osteoarthritis Outcome Score measure: Knee injury and Osteoarthritis Outcome Score measure: Knee injury and Osteoarthritis Outcome Score measure: 36-Item Short Form Health Survey measure: 36-Item Short Form Health Survey measure: 36-Item Short Form Health Survey measure: 36-Item Short Form Health Survey measure: Forgotten joint score measure: Forgotten joint score measure: Forgotten joint score measure: Forgotten joint score measure: Radiographic evaluation of prosthetic femoral component positioning sex: ALL minimumAge: 50 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Stefano Zaffagnini status: RECRUITING city: Bologna state: Italia country: Italy name: Stefano Zaffagnini, MD role: CONTACT phone: 051 6366075 email: stefano.zaffagnini@unibo.it lat: 44.49381 lon: 11.33875 hasResults: False
nctId: NCT06321029 id: 4-22-ICTSHD-44 briefTitle: Electronic Diabetes Tune-Up Group (eDTU) for African Americans overallStatus: RECRUITING date: 2023-10-19 date: 2024-12-31 date: 2025-03-31 date: 2024-03-20 date: 2024-03-20 name: Indiana University class: OTHER name: Indiana University Health briefSummary: The primary aims of this study are:
2. To test differences in diabetes distress and A1c change scores between intervention (changes in T2 to T4) and waitlist control (change in T1 to T2) by intervention group (eDTU vs. waitlist control; iDTU vs. waitlist control). The hypothesis is that both the eDTU and iDTU groups will show significant improvements in diabetes distress and A1c compared to waitlist control. In order to conserve sample size and budget, participants in each intervention group will serve as their own waitlist control.
Secondary Objective. The secondary aim of the study is to evaluate changes in depressive symptoms, diabetes self-efficacy, and general and diabetes-specific quality of life in intervention (T2-T3 \& T4) compared to waitlist control (T1-T2). An exploratory aim will be to compare changes in eDTU to the iDTU pre/post intervention (T2-T3 \& T4). The hypothesis is that both groups will show comparable improvements in diabetes distress and A1c. conditions: Diabetes Mellitus, Type 2 conditions: Diabetes Complications studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Single group waitlist control primaryPurpose: TREATMENT masking: NONE count: 60 type: ESTIMATED name: Diabetes Tune-Up Group measure: Diabetes Distress Scale-17 (DDS-17) measure: HbA1c (A1c) measure: Acceptability of intervention (content and delivery modality) measure: Feasibility of intervention and delivery modality measure: Patient Health Questionnaire-9 (PHQ-9) measure: Confidence in Diabetes Self-Care (CDSC) measure: Short Form-12 (SF-12) measure: Diabetes Therapy-Related Quality of Life Questionnaire sex: FEMALE minimumAge: 21 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Indiana University School of Medicine status: RECRUITING city: Indianapolis state: Indiana zip: 46202 country: United States name: Barb Myers, MS role: CONTACT phone: 317-278-7339 email: bamyers@iu.edu name: Mary de Groot, PhD role: CONTACT phone: 317-278-1965 email: mdegroot@iu.edu name: Mary de Groot, PhD role: PRINCIPAL_INVESTIGATOR lat: 39.76838 lon: -86.15804 hasResults: False
nctId: NCT06321016 id: 2023111039 briefTitle: POZIKIDS: Exercise and Comprehensive Care to Improve the Quality of Life of Children and Adolescents With Cancer acronym: PoziKids overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2026-06-30 date: 2026-12-30 date: 2024-03-20 date: 2024-03-20 name: Nere Mendizabal class: OTHER_GOV briefSummary: Objective: To assess the feasibility of a supervised, controlled and personalised physical exercise programme and its potential efficacy in improving functional capacity and quality of life in children and adolescents with cancer.
Methods: The learning collaborative approach based on the Institute for Healthcare Improvement Breakthrough Series Collaborative Model will be followed through quarterly Plan-Do-Study-Act (P-D-S-A) cycles. Participants: For feasibility, at least, 45 patients will be included in 3 successive PDSA cycles of at least 15 patients each, aged 4-18 years diagnosed with any type of cancer. Variables: clinical and socio-demographic, body composition, physical condition and mobility, quality of life, physical activity and implementation. Intervention: Everyone will receive a physical exercise intervention combining strength and aerobic capacity work. Initially it will be carried out in the hospital setting, and later in streaming supervised by a professional. The intervention will be modelled through a formative evaluation process with the collaboration of all the agents involved, experimenting in each cycle with an increasingly adapted version of the exercise programme.
Statistical analysis: Recruitment rates will be calculated, characteristics associated with project participation and adherence to the exercise programme will be identified. Outcome variables will be compared before and after the intervention, identifying those with the greatest validity, reliability and sensitivity to change, which will then be used in phase II and III trials. conditions: Exercise conditions: Childhood Cancer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 45 type: ESTIMATED name: Physical exercise program name: Type of the physical exercise program measure: Quarterly recruitment rates assessed by comparing those who participate with those who do not. measure: Adherence rates assessed by the proportion of sessions completed and adherence to the prescribed exercise protocol measure: Body composition assessed by the Body Mass Index measure: Muscle mass measure: Bone mineral density measure: Physical condition assessed by the 6 min walking test and manual grip test with a dynamometer measure: Muscular strength assessed by manual grip test with a dynamometer measure: General Quality of life assessed by the PedsQL 4.0 questionnaire measure: Specific Quality of life assessed by the PedsQL cancer questionnaire measure: Fatigue assessed by the PedsQL Multidimensional Fatigue Scale Acute Version (PedsQL-MFS) measure: Physical activity level assessed by accelerometers measure: Security assessment measure: Costs associated estimation measure: Implementation barriers and facilitators sex: ALL minimumAge: 4 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT hasResults: False
nctId: NCT06321003 id: OCT01 briefTitle: SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography acronym: SYMILIS OCT overallStatus: RECRUITING date: 2024-03-13 date: 2027-04-01 date: 2027-04-01 date: 2024-03-20 date: 2024-03-20 name: University of Palermo class: OTHER briefSummary: This clinical trial aims to assess the efficacy of Optical Coherence Tomography (OCT) in the early diagnosis of oral cancer. It focuses on Oral Potentially Malignant Disorders (OPMDs) as precursors to Oral Squamous Cell Carcinoma (OSCC). Despite the availability of oral screening, diagnostic delays persist, underscoring the importance of exploring non-invasive methodologies. The OCT technology provides cross-sectional analysis of biological tissues, enabling a detailed evaluation of ultrastructural oral mucosal features.
The trial aims to compare OCT preliminary evaluation with traditional histology, considered the gold standard in oral lesion diagnosing. It seeks to create a database of pathological OCT data, facilitating the non invasive identification of carcinogenic processes. The goal is to develop a diagnostic algorithm based on OCT, enhancing its ability to detect characteristic patterns such as the keratinized layer, squamous epithelium, basement membrane, and lamina propria in oral tissues affected by OPMDs and OSCC.
In summary, the trial not only evaluates OCT as a diagnostic tool but also aims to integrate AI to develop a standardized approach that enhances the accuracy of oral cancer diagnosis, providing a significant contribution to clinical practice. conditions: Oral Squamous Cell Carcinoma conditions: Oral Potentially Malignant Disorder conditions: Oral Leukoplakia conditions: Proliferative Verrucous Leukoplakia conditions: Oral Lichen Planus conditions: Oral Lichenoid Lesion conditions: Graft-versus-host-disease conditions: Oral Erythroplakia conditions: Actinic Keratoses conditions: Actinic Cheilitis conditions: Oral Cancer conditions: Oral Disease studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 200 type: ESTIMATED name: OCT (Optical Coherence Tomography) measure: Phase I: Standardization of Biopsy and OCT Imaging Techniques measure: Phase II: Development of Standardized OCT Patterns, Creation of Comprehensive Image Repository, and Training Algorithms measure: Phase III: Development and Large-Scale Validation of Diagnostic OCT Software sex: ALL minimumAge: 18 Years maximumAge: 99 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Palermo status: RECRUITING city: Palermo country: Italy role: CONTACT phone: 091 238 93011 email: pec@cert.unipa.it lat: 38.13205 lon: 13.33561 hasResults: False
nctId: NCT06320990 id: 0074-24-CB briefTitle: Chemoprevention With Tamoxifen in Pre-Invasive Pancreas Mucinous Cystic Neoplasms Not Undergoing Immediate Resection acronym: MCN_Tam overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-11 date: 2027-05 date: 2024-03-20 date: 2024-03-20 name: University of Nebraska class: OTHER briefSummary: This is an open-label pilot study of tamoxifen as chemoprevention in patients with pancreatic MCN who will not undergo immediate resection. Up to 15 subjects will be enrolled and take tamoxifen 20mg by mouth daily for up to 24 weeks. conditions: Pancreatic Cyst conditions: Pancreatic Mucinous Cystic Neoplasm studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: PREVENTION masking: NONE count: 15 type: ESTIMATED name: Tamoxifen 20mg measure: Feasibility, by adherence rate measure: Feasibility, by retention rate measure: Objective response rate (ORR) of pancreatic MCN sex: ALL minimumAge: 19 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Nebraska Medical Center city: Omaha state: Nebraska zip: 68198 country: United States name: Christina Hoy, DNP role: CONTACT email: choy@nebraskamed.com name: Kelsey Klute, MD role: PRINCIPAL_INVESTIGATOR lat: 41.25626 lon: -95.94043 hasResults: False
nctId: NCT06320977 id: ESS/FSA-397/23-2 briefTitle: The Influence of Acute Static Stretching on the Ankle Joint-position Sense of Soccer Players overallStatus: COMPLETED date: 2024-02-12 date: 2024-03-13 date: 2024-03-29 date: 2024-03-20 date: 2024-04-09 name: University Fernando Pessoa class: OTHER briefSummary: The aim of this study isto investigate the influence of acute static stretching on the ankle joint position sense of soccer players. conditions: Healthy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 19 type: ACTUAL name: Static Stretching measure: Absolute angular error measure: Relative angular error measure: Variable angular error sex: MALE minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT facility: Escola Superior de Saúde Fernando Pessoa city: Porto zip: 4200-253 country: Portugal lat: 41.14961 lon: -8.61099 hasResults: False
nctId: NCT06320964 id: R01HD108252_1 id: R01HD108252 type: NIH link: https://reporter.nih.gov/quickSearch/R01HD108252 briefTitle: The TARANG Intervention acronym: TARANG Pilot overallStatus: COMPLETED date: 2023-07-14 date: 2024-01-21 date: 2024-01-21 date: 2024-03-20 date: 2024-03-20 name: University of California, San Francisco class: OTHER name: Network for Engineering and Economics Research and Management name: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) name: Vikalp Sansthan briefSummary: The mixed methods pilot study aims to evaluate the acceptability, feasibility, and implementation challenges of the TARANG intervention in villages in rural/tribal Rajasthan to inform the study design and operational details for a larger cluster-randomized controlled trial. conditions: Feasibility conditions: Acceptability conditions: Family Planning conditions: Unintended Pregnancy studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: PREVENTION masking: NONE count: 135 type: ACTUAL name: TARANG measure: Feasibility of the intervention measure: Acceptability measure: Usefulness sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Vikalp Sansthan city: Udaipur state: Rajasthan country: India lat: 24.58584 lon: 73.71346 hasResults: False
nctId: NCT06320938 id: 2024/18 briefTitle: Effectiveness of Neuroscience-based Pain Education in Patients With Chronic Neck Pain overallStatus: NOT_YET_RECRUITING date: 2024-04-18 date: 2024-09-15 date: 2025-03-15 date: 2024-03-20 date: 2024-03-27 name: Turkoglu Dr. Kemal Beyazit State Hospital class: OTHER briefSummary: The effectiveness of neuroscience-based pain education, myofascial induction technique, and home exercise programs will be compared in patients with chronic neck pain. conditions: Cervical Spine Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 60 type: ESTIMATED name: Neuroscience-Based Pain Education Combined with Home Exercise Program name: Myofascial Induction Techniques Combined with Home Exercise Program name: Home Exercises Group measure: Short Form McGill Pain Questionnaire measure: Algometric Digital Measurement measure: Central Sensitization Inventory measure: Head Posture Evaluation measure: Neck Disability Index measure: Pittsburgh Sleep Quality Index measure: 36-Item Short Form Health Survey Questionnaire measure: Pain Catastrophizing Scale sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Türkoğlu Dr. Kemal Beyazıt State Hospital city: Kahramanmaraş country: Turkey lat: 37.5847 lon: 36.92641 hasResults: False
nctId: NCT06320925 id: SYK-SM-2022-02 briefTitle: SportsPro: Post-Market Clinical Follow Up Study overallStatus: RECRUITING date: 2023-12-05 date: 2024-06-30 date: 2024-12-01 date: 2024-03-20 date: 2024-03-22 name: Stryker Endoscopy class: INDUSTRY briefSummary: Retrospective, multi-center, chart review (only to include data that is part of the surgeons' standard practice) conditions: Shoulder Injuries conditions: Knee Injuries conditions: Hip Injuries studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: RETROSPECTIVE count: 1500 type: ESTIMATED name: Standard of Care Treatment measure: ASES measure: iHOT-12 measure: mHHS sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Musculoskeletal-Orthopedic Research and Education Foundation status: RECRUITING city: Phoenix state: Arizona zip: 85023 country: United States name: Wafa Mohsin role: CONTACT email: wafa.mohsin@more-foundation.org name: Michael Amini, MD role: PRINCIPAL_INVESTIGATOR lat: 33.44838 lon: -112.07404 facility: Steadman Hawkins Clinic Denver status: RECRUITING city: Englewood state: Colorado zip: 80112 country: United States name: Lauren Heylmun role: CONTACT email: LAUREN.HEYLMUN@CUANSCHUTZ.EDU name: James Genuario, MD role: PRINCIPAL_INVESTIGATOR lat: 39.64777 lon: -104.98776 facility: TSAOG Orthopaedics & Spine status: RECRUITING city: San Antonio state: Texas zip: 78258 country: United States name: Amanda Strickland role: CONTACT email: astrickland@brioresearch.org name: Robert Hartzler, MD role: PRINCIPAL_INVESTIGATOR lat: 29.42412 lon: -98.49363 hasResults: False
nctId: NCT06320912 id: TIPS01 briefTitle: Efficacy and Safety of Intraparenchymal Portal Vein Covered Stents in Treating Portal Hypertension and Its Complications overallStatus: NOT_YET_RECRUITING date: 2024-04-05 date: 2026-06-01 date: 2026-11-01 date: 2024-03-20 date: 2024-03-20 name: Shanghai Shenqi Medical Technology Co., Ltd class: INDUSTRY briefSummary: The objective of this study is to assess the non-inferiority of the intraparenchymal portal vein covered stent in terms of safety and efficacy for managing portal hypertension and its related complications, in comparison to the currently available TIPS Covered Stent System by GORE. conditions: Portal Hypertension studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 258 type: ESTIMATED name: The intraparenchymal portal vein covered stent name: TIPS Covered Stent System GORE measure: Postoperative Stent Patency Rate measure: Immediate Postoperative Technical Success Rate measure: Incidence of Secondary Interventions at 1 Month, 6 Months, and 12 Months Postoperatively measure: Incidence of Stent Dysfunction at 1 Month, 6 Months, and 12 Months Postoperatively measure: Incidence of Major Adverse Events (MAE) at 1 Month, 6 Months, and 12 Months Postoperatively measure: All-Cause Mortality Rates at 1 Month, 6 Months, and 12 Months Postoperatively measure: Incidence of Grade II or Higher Hepatic Encephalopathy at 1 Month, 6 Months, and 12 Months Postoperatively measure: Incidence of Portal Hypertension Rebleeding Confirmed by Endoscopy or Clinical Investigator at 1 Month, 6 Months, and 12 Months Postoperatively (For Original Bleeding Subjects Only) measure: Incidence of Ultrasound-Confirmed Recurrence of Grade 2 or Higher Ascites due to Portal Hypertension at 1 Month, 6 Months, and 12 Months Postoperatively (For Subjects with Original Ascites Only) measure: Incidence of Adverse Events/Serious Adverse Events sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Southern Medical University Nanfang Hospital city: Guangzhou state: Guangdong country: China name: Jianbo Zhao role: CONTACT lat: 23.11667 lon: 113.25 hasResults: False
nctId: NCT06320899 id: SpineShape_CH_001 id: BASEC 2023-D0092 type: OTHER domain: Ethics Committee Bern briefTitle: Mid- or High-flex Rods Versus Low-flex Rods of SpineShape System IV for Treatment of Degenerative Lumbar Spine Diseases overallStatus: NOT_YET_RECRUITING date: 2024-04-02 date: 2031-08-31 date: 2031-08-31 date: 2024-03-20 date: 2024-03-20 name: SpineSave AG class: INDUSTRY briefSummary: The purpose of this multi-center, randomized, clinical study is to show that the treatment of degenerative lumbar spine with high- or mid-flex rods is not inferior to the treatment with low-flex rods in terms of clinical and safety-related results.
The primary aim is to compare the reduction in back pain after the treatment with high- or mid-flex rods with that after treatment with low-flex rods. Secondary, the functionality after treatment with high- or mid-flex rods will be compared to that after treatment with low-flex rods. conditions: Degenerative Lumbar Spinal Stenosis conditions: Facet Joint Arthrosis conditions: Spondylarthritis conditions: Discopathy conditions: Degenerative Spondylolisthesis conditions: Instability Lumbar Spine studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 126 type: ESTIMATED name: SpineShape System IV straight rod elastic name: SpineShape System IV straight rod medium name: SpineShape System IV straight rod stiff measure: VAS Score lower back pain measure: VAS Score leg pain measure: walking duration measure: medication consumption measure: adverse events measure: segmental mobility index level measure: ability to work/ activity (for retirees) sex: ALL minimumAge: 18 Years maximumAge: 99 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06320886 id: Soh-Med-24-02-05MS briefTitle: Role of Ultrasonography in Acute Abdomen in Adults in Correlation to Computed Tomography Scan overallStatus: RECRUITING date: 2024-02-01 date: 2024-10-31 date: 2024-10-31 date: 2024-03-20 date: 2024-03-20 name: Sohag University class: OTHER briefSummary: The study aims to evaluate the role of Ultrasonography in the diagnosis of the cause of acute abdominal pain in 50 adults presenting in the ER at Sohag University Hospital and compares it to the Computed Tomography scan results of the same patients to discover the superiority of both over the other in the diagnosis of different acute abdomen cases. conditions: Acute Abdomen conditions: In Adults studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: OTHER count: 50 type: ESTIMATED name: Diagnostic Test measure: Comparison between the role of Ultrasonography and Computed Tomography in Acute Abdomen diagnosis sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sohag University Hospital status: RECRUITING city: Sohag country: Egypt name: Magdy M Amin, Proffesor role: CONTACT lat: 26.55695 lon: 31.69478 hasResults: False
nctId: NCT06320873 id: zselcuk1 briefTitle: The Effect of Respiratory on Sports Performance in Archers overallStatus: COMPLETED date: 2021-07-26 date: 2022-01-01 date: 2022-01-01 date: 2024-03-20 date: 2024-03-20 name: Halic University class: OTHER briefSummary: Purpose: The physical, physiological, and functional characteristics of archers affect target shooting performance. In our study, we aimed to examine the effect of pulmonary functions and respiratory muscle strength on sports performance in archers.
Methods: Our study included 46 (27 female, 19 male) professional archers registered in archery sports clubs. Sociodemographic and physical characteristics were recorded. Pulmonary function test (PFT), respiratory muscle strength, shooting performance test, Moberg-pickup collection test, Nelson hand reaction test, and Fatigue Severity Scale (FSS) were applied to all participants. conditions: Sports Physical Therapy studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 46 type: ACTUAL name: archery respiratory parameters measure: FEV1 (liter) measure: FEV1 (%-percentage) measure: FVC (liter) measure: FVC (%-percentage) measure: FEV1/FVC (percentage) measure: Inspiratory muscle test measure: Expiratory muscle test measure: Shooting performance measure: Nelson Hand Reaction Test measure: Moberg-pickup collection test measure: The Fatigue Severity Scale (FSS) sex: ALL minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT facility: Halic University city: Istanbul country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False