hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06354491 id: 2023-1494 briefTitle: An Imaging-based Quantitative Biomarker Assay for NAFLD in Children overallStatus: RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2027-04-01 date: 2024-04-09 date: 2024-04-09 name: University of Wisconsin, Madison class: OTHER briefSummary: This study will validate recently developed Magnetic Resonance Imaging (MRI) and Ultrasound (US) based methods for liver fat quantification in children with obesity and healthy range of body mass index (BMI). conditions: NAFLD conditions: NASH studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 24 type: ESTIMATED name: Magnetic Resonance Imaging (MRI) name: Ultrasound (US) measure: MRI measure: Quantitative US sex: ALL minimumAge: 10 Years maximumAge: 14 Years stdAges: CHILD facility: University of Wisconsin, Madison status: RECRUITING city: Madison state: Wisconsin zip: 53705 country: United States name: Gemma Gliori, MS role: CONTACT phone: 608-262-7269 email: ggliori@uwhealth.org name: Suzanne Hanson, BS role: CONTACT phone: 608-262-7269 email: shanson@uwhealth.org lat: 43.07305 lon: -89.40123 hasResults: False
nctId: NCT06354478 id: ms-103-2021 briefTitle: IV Dexmedetomidine vs Oral Gabapentin and Their Combination for Postoperative Analgesia in Cancer Patients Undergoing Modified Radical Mastectomy overallStatus: COMPLETED date: 2021-01-01 date: 2022-02-01 date: 2022-07-01 date: 2024-04-09 date: 2024-04-09 name: National Cancer Institute, Egypt class: OTHER briefSummary: Breast cancer is the most common malignant tumour among females with an incidence of about 2.1 million women every year.Nearly about 40-60% of breast surgery patients develop severe acute postoperative pain.⁴ Opioids are the current best standard drugs for postoperative pain relief, however, exposure to large doses of opioids leads to multiple side effects like prolonged sedation, respiratory depression, nausea, and vomiting.We are comparing two different drugs and their combination for perioperative analgesia for MRM.
This work is a comparative study that aims to compare the analgesic effects of perioperative IV infusion of dexmedetomidine, preoperative oral gabapentin, and their combination in patients undergoing modified radical mastectomy surgery regarding the time of first rescue analgesia, postoperative morphine consumption, and possible complications. conditions: Breast Cancer conditions: Pain, Postoperative conditions: Pain, Acute studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Both patients and Investigator for postoperative pain will be blinded:
* Group 3(DG): (n=30) Patients will receive oral gabapentin capsules for 1 hour preoperatively and intraoperative intravenous infusion of dexmedetomidine with general anaesthesia. whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 90 type: ACTUAL name: Dexmedetomidine Hydrochloride 0.5 MG/ML name: Gabapentin measure: The time to first rescue analgesia during the first 24 hour Postoperatively. measure: Total postoperative morphine consumption till the first 24 hours measure: The degree of postoperative sedation according to Ramsay scores measure: VAS scores both at rest and during shoulder movement measure: Postoperative nausea and vomiting (PONV) as side effects of morphine. sex: FEMALE minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: National Cancer Institute city: Cairo country: Egypt lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06354465 id: IRB1967355 id: K23DA055695 type: NIH link: https://reporter.nih.gov/quickSearch/K23DA055695 briefTitle: Injectable Extended-Release Buprenorphine (XR-B) in a Correctional Setting: Qualitative Interviews overallStatus: RECRUITING date: 2023-07-01 date: 2024-07-01 date: 2024-07-01 date: 2024-04-09 date: 2024-04-09 name: Lifespan class: OTHER name: National Institute on Drug Abuse (NIDA) briefSummary: This qualitative study investigates the potential benefits and challenges of using a once-a-month injectable medication, known as extended-release buprenorphine (XR-B), to treat individuals with opioid use disorder (OUD) within a correctional setting. The research aims to understand if XR-B can be a feasible and effective alternative to the standard daily treatment and to identify which groups within the prison population may benefit the most from this treatment. In-depth interviews are conducted with incarcerated individuals and relevant stakeholders. conditions: Opioid Use Disorder conditions: Criminal Justice conditions: Treatment Adherence and Compliance studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 25 type: ESTIMATED measure: Qualitative Transcripts sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Rhode Island Department of Corrections status: RECRUITING city: Cranston state: Rhode Island zip: 02920 country: United States name: Jessica Migliaccio role: CONTACT phone: 401-462-3921 email: doc.planning@doc.ri.gov lat: 41.77982 lon: -71.43728 typeAbbrev: Prot hasProtocol: True hasSap: False hasIcf: False label: Study Protocol date: 2023-10-09 uploadDate: 2024-03-31T17:37 filename: Prot_000.pdf size: 125769 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2023-01-07 uploadDate: 2024-04-04T09:46 filename: ICF_001.pdf size: 488632 hasResults: False
nctId: NCT06354452 id: HGG2024_01 briefTitle: Effect of Statin Therapy on Sepsis-related Mortality in Intensive Care Unit Patients acronym: HGG_UCI1 overallStatus: COMPLETED date: 2018-01-01 date: 2019-12-31 date: 2020-01-31 date: 2024-04-09 date: 2024-04-09 name: Hospital de Granollers class: OTHER name: Department of Health, Generalitat de Catalunya briefSummary: The average age of patients with sepsis has increased in recent years in parallel with the incidence of sepsis. Many of these patients are frail and require various medications for the treatment of their chronic diseases. Common treatments, including e.g. sarcopenic drugs (statins, sulphonylureas, methyglinides), antioxidants that prevent sarcopenia (allopurinol) or immunoregulators (corticosteroids) may influence the survival and functional prognosis of these patients. Knowing which drugs influence sepsis survival and to what degree patients who survive sepsis have functional deterioration and increased comorbidity and which modifiable factors limit this may be essential. conditions: Sepsis conditions: Septic Shock studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: OTHER count: 59578 type: ACTUAL name: Person-level linkage of the database looking for relationship with sepsis survival and previous intake of certain drug families and previous dependence on health services. measure: Death due to sepsis sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hospital General de Granollers city: Granollers state: Barcelona zip: 08402 country: Spain lat: 41.60797 lon: 2.28773 hasResults: False
nctId: NCT06354439 id: 77015224.6.1001.5327 briefTitle: Use of Letrozole for Ectopic Pregnancy acronym: EcZOL overallStatus: RECRUITING date: 2024-03-27 date: 2026-12-31 date: 2026-12-31 date: 2024-04-09 date: 2024-04-09 name: Hospital de Clinicas de Porto Alegre class: OTHER briefSummary: A randomized clinical trial using oral letrozole 10mg/day for 7 days, for treating early cases of ectopic pregnancy, compared to intramuscular methotrexate conditions: Ectopic Pregnancy studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized clinical trial primaryPurpose: TREATMENT masking: NONE maskingDescription: Due to the nature of the outcome and the interventions, blinding was not considered an issue. count: 130 type: ESTIMATED name: Letrozole tablets name: Methotrexate Sodium measure: levels of beta fraction of human chorionic gonadotropin (beta-hCG) sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hospital de Clínicas de Porto Alegre status: RECRUITING city: Porto Alegre state: RS zip: 90035-903 country: Brazil name: RICARDO F SAVARIS, MD,PHD role: CONTACT phone: 55 51 33598117 email: rsavaris@hcpa.edu.br name: Michele S Savaris, BBA role: CONTACT phone: 555133598624 email: msavaris@hcpa.edu.br lat: -30.03306 lon: -51.23 hasResults: False
nctId: NCT06354426 id: BVT2022/01 briefTitle: Short-term Mortality Prediction by the SOFA Score in Acute Decompensated Heart Failure overallStatus: COMPLETED date: 2022-07-01 date: 2023-08-31 date: 2023-08-31 date: 2024-04-09 date: 2024-04-09 name: Hanoi Heart Hospital class: OTHER briefSummary: Data on the use of sequential organ failure assessment (SOFA) in patients with cardiovascular disease are increasing. Several studies demonstrated that the SOFA score can identify short-term mortality in patients with acute decompensated heart failure (ADHF). This study was conducted to determine the prognostic value of the admission SOFA score in patients hospitalised for ADHF and to assess its ability in predicting the 30-day readmission rate. conditions: Acute Decompensated Heart Failure studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 216 type: ACTUAL measure: Mortality measure: Re-admission rate sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hanoi Heart Hospital city: Hanoi state: Hoan Kiem zip: 110000 country: Vietnam lat: 21.0245 lon: 105.84117 hasResults: False
nctId: NCT06354413 id: 2023-2261 briefTitle: Outcomes of Concomitant Bypass Surgery in Septal Myectomy overallStatus: COMPLETED date: 2009-01 date: 2020-12 date: 2023-12 date: 2024-04-09 date: 2024-04-09 name: Chinese Academy of Medical Sciences, Fuwai Hospital class: OTHER briefSummary: To investigate clinical characteristics and survival outcomes of patients with obstructive hypertrophic cardiomyopathy who underwent concomitant coronary artery bypass grafting during septal myectomy. conditions: Hypertrophic Cardiomyopathy conditions: Coronary Artery Disease conditions: Myocardial Bridging studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 320 type: ACTUAL name: CABG during myectomy measure: all-cause mortality measure: cardiac-related deaths and readmission sex: ALL minimumAge: 8 Years maximumAge: 90 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06354400 id: 2022/001-002 briefTitle: Core Stabilization Training on Chest Expansion, Functional Capacity, Trunk Muscle Endurance in Hearing-Impaired Children overallStatus: RECRUITING date: 2024-03-30 date: 2024-05-30 date: 2024-06-30 date: 2024-04-09 date: 2024-04-09 name: Bezmialem Vakif University class: OTHER name: Nuh Naci Yazgan University briefSummary: Children's motor skills and physical performance increase with age due to the development of neuromuscular and cardiorespiratory systems. Sensory impairment seen in children with hearing loss can cause balance and coordination disorders, as well as decreased muscle strength and respiratory functions.
Anatomically, core stabilization is provided by the diaphragm, abdominal, hip, pelvic floor, and gluteal muscles. Training for these muscles is intended to improve strength, endurance, and neuromuscular control. This training can help to improve the control of intra-abdominal pressure, intersegmental control of the spine, and muscular control of trunk movement. It also helps in strengthening the respiratory muscles, especially the main inspiratory muscle, the diaphragm. In this study, the effects of core stabilization training on children with hearing impairments' thoracic mobility, functional ability, and trunk muscle endurance will be examined. conditions: Core Stabilization conditions: Respiration conditions: Functional Capacity conditions: Endurance conditions: Hearing Impaired Children studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 26 type: ESTIMATED name: Core stabilization training measure: Chest expansion measure: Functional capacity measure: Trunk muscle endurance sex: ALL minimumAge: 10 Years maximumAge: 15 Years stdAges: CHILD facility: Nuh Naci Yazgan University status: RECRUITING city: Kayseri country: Turkey name: Busra Kepenek-Varol, PhD, PT role: CONTACT phone: +905449106628 email: bkvarol@nny.edu.tr name: Busra Kepenek Varol, PhD, PT role: PRINCIPAL_INVESTIGATOR lat: 38.73222 lon: 35.48528 hasResults: False
nctId: NCT06354387 id: CMUH110-REC3-246 briefTitle: Alectinib in Combination With Nivolumab in the Treatment of Recurrent or Refractory HCC Patients Guided With Serum RNase1 and Tumor Expression of PD-L1 overallStatus: RECRUITING date: 2022-02-16 date: 2024-12-31 date: 2025-06-01 date: 2024-04-09 date: 2024-04-09 name: China Medical University Hospital class: OTHER briefSummary: Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer-related death and the second most deadly malignancy in Taiwan. Despite decades' intensive studies, surgery and local-regional chemo-embolization, radio-frequency ablation or radiation therapy remain the mainstay of HCC treatments. conditions: Hepatocellular Carcinoma studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 8 type: ESTIMATED name: Alectinib (Alecensa), Nivolumab (Opdivo) measure: Objective response rate(ORR) measure: PFS measure: TTP measure: DOR measure: DCR measure: OS sex: ALL minimumAge: 20 Years stdAges: ADULT stdAges: OLDER_ADULT facility: CMUH status: RECRUITING city: Taichung country: Taiwan name: Chang-Fang Chiu, PhD role: CONTACT phone: 8864-22052121 email: 005686@tool.caaumed.org.tw lat: 24.1469 lon: 120.6839 hasResults: False
nctId: NCT06354374 id: 24-026 briefTitle: Soft Tissue Volume, Dimensions and Tomographic Alveolar Ridge Classification System for Dental Implant Treatment. overallStatus: RECRUITING date: 2024-02-22 date: 2024-07 date: 2024-12 date: 2024-04-09 date: 2024-04-09 name: Ain Shams University class: OTHER name: British University In Egypt briefSummary: Despite the importance of soft tissue dimensions for periodontal, restorative, implant, and orthodontic treatment, the current classifications of tomographic alveolar ridge topography lack the soft tissue component(Tolstunov, 2014). Therefore, the present study will be to evaluate the relationship between soft tissue volume and the dimensions \& tomographic alveolar ridge classes as well as to incorporate the soft tissue volumetric evaluation in the classification system. conditions: Soft Tissue Volume studyType: OBSERVATIONAL observationalModel: ECOLOGIC_OR_COMMUNITY timePerspective: CROSS_SECTIONAL count: 350 type: ESTIMATED name: volume survey measure: the relationship between soft tissue volume & tomographic alveolar ridge classes sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ahmed Hamdy status: RECRUITING city: Al Shorouk City state: Cairo zip: 11837 country: Egypt name: Ahmed Hamdy role: CONTACT phone: +201061112512 email: ahmed.esmaail@bue.edu.eg hasResults: False
nctId: NCT06354361 id: 17440 briefTitle: Trauma-Informed Goal Management Training for Public Safety Personnel (PSP) With Post-traumatic Stress Disorder (PTSD) overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-05 date: 2026-09 date: 2024-04-09 date: 2024-04-18 name: McMaster University class: OTHER name: Workplace Safety and Insurance Board briefSummary: Goal Management Training (GMT) is a program designed to help improve cognitive functioning. For this study, researchers have worked closely with the developers of this program to create a modified version called Trauma-Informed Goal Management Training (TI-GMT), that is more sensitive to the needs of public safety personnel (PSP) diagnosed with Post-Traumatic Stress Disorder (PTSD).
nctId: NCT06354348 id: GastrectomyUSG briefTitle: Practical Ultrasonographic Detection of Sarcopenia in Patients With Long-term Gastrectomy overallStatus: COMPLETED date: 2023-12-06 date: 2024-03-30 date: 2024-03-30 date: 2024-04-09 date: 2024-04-09 name: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital class: OTHER briefSummary: The investigators aimed to evaluate long-term sarcopenia in patients with total and distal gastrectomy by measuring the anterior thigh muscle with USG, which is a more specific and easy method. conditions: Sarcopenia conditions: Gastrectomy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: DIAGNOSTIC masking: NONE count: 90 type: ACTUAL name: USG, Grip strength, Chair stand test (CST) measure: Sarcopenia (Sonographic thigh adjustment ratio (STAR) was calculated by dividing the anterior thigh muscle thickness (mm) by BMI ) sex: ALL minimumAge: 45 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital city: Ankara country: Turkey lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06354335 id: 1-16-02-62-20 briefTitle: Impact of a Major Organizational Change on Employee Productivity and Mental Health acronym: PRO-MENTA overallStatus: ACTIVE_NOT_RECRUITING date: 2022-03-01 date: 2024-12-31 date: 2026-12-31 date: 2024-04-09 date: 2024-04-11 name: Aarhus University Hospital class: OTHER name: University of Aarhus name: Herning Hospital name: Bispebjerg Hospital briefSummary: The study investigates the short- and long-term impact of a major organizational change on employee health and productivity. Changes in organizations is a common aspect of modern work life in all sectors and public healthcare is no exception. However, emerging evidence suggests that organizational changes may be a potential stressor which can impact on employee well-being and contribute to stress-related health problems. Using a large-scale natural experiment, the overall aim of the study is to investigate the impact of a major organizational change that took place during 2016-19 on employee health and productivity. In addition, we aim to identify groups that may be at increased risk of experiencing negative consequences of the reorganization. These at-risk groups can in turn be candidates for extended preventive measures when planning future major organizational changes. conditions: Work Related Stress conditions: Mental Health Issue conditions: Work-related Illness studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 31555 type: ACTUAL name: Employees exposed to a major hospital reorganisation measure: Employee health measured by rate of absenteeism, use of health care services and redeemed drug prescriptions measure: Workplace productivity measured by number of patient contacts and medical procedures sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Aarhus University Hospital city: Aarhus state: Central Denmark Region zip: 8200 country: Denmark lat: 56.15674 lon: 10.21076 hasResults: False
nctId: NCT06354322 id: APHP230630 briefTitle: Unclassified GENotypes of Autoinflammatory Diseases and AA Amyloidosis acronym: IPHYGENI MAI overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-06 date: 2034-05 date: 2024-04-09 date: 2024-04-09 name: Assistance Publique - Hôpitaux de Paris class: OTHER briefSummary: Patients with autoinflammatory diseases (AID) have recurrent episodes of systemic inflammation accompanied by nonspecific elevation of blood inflammation markers typically absent between attacks. A complication of autoinflammatory diseases is AA amyloidosis, which can lead to renal failure and dialysis. Advances in genetic analysis have led to the identification of new autoinflammatory diseases and thus new pathophysiological pathways.
genetic analysis sometimes has limitations in the diagnosis of AID which can only be overcome by pathophysiological studies of the variants found. conditions: AA Amyloidosis conditions: Autoinflammatory Disease studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 200 type: ESTIMATED measure: Exploration of VUS in AutoInflammatory Diseases measure: Pathophysiology of Autoinflammatory Diseases measure: Role of other innate immune cells in AutoInflammatory Diseases measure: Improve knowledge of AA amyloidosis sex: ALL minimumAge: 3 Years maximumAge: 80 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06354309 id: vr_study briefTitle: The Impact of Immersive Virtual Reality Training on Adult: Motion Sickness, and Ocular Surface: A Pilot Study overallStatus: COMPLETED date: 2023-08-01 date: 2023-10-20 date: 2023-10-20 date: 2024-04-09 date: 2024-04-09 name: He Eye Hospital class: OTHER briefSummary: The research project titled "The Impact of Immersive Virtual Reality Training on Adult: Motion Sickness, and Ocular Surface: A Pilot Study" aimed to evaluate the initial safety impact of head-mounted virtual reality (HMVR) devices with virtual reality amblyopia training games on postural stability, motion sickness, and ocular surface in healthy adult participants. 38 adults (76 eyes) with normal corrected vision and stereo vision were recruited. All subjects used HMVR device for two consecutive training sessions (30 minutes each, 10 minutes intervals). Before training, after the first training and the second training, recorded the results including best corrected visual acuity (BCVA), ocular position, stereo vision, postural stability, non-invasive tear breakup time (NITBUT), tear meniscus height (TMH), red eye analysis, lipid layer classification (TFLL), eye blink frequency, eye surface temperature, simulator sickness questionnaire (SSQ) score, ocular surface disease index (OSDI) dry eye questionnaire score, visual quality questionnaire score and visual fatigue questionnaire score. conditions: Amblyopia conditions: Motion Sickness conditions: Dry Eye studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 38 type: ACTUAL name: Virtual reality game measure: Simulator Sickness Questionnaire Score measure: Postural stability measure: Non-invasive tear breakup time measure: Tear meniscus height measure: Lipid layer classification measure: Eye blink frequency measure: Eye surface temperature measure: Ocular surface disease index dry eye questionnaire score measure: Visual quality questionnaire score measure: Visual fatigue questionnaire score sex: ALL minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: He Eye Hospital city: Shenyang state: Liaoning zip: 110034 country: China lat: 41.79222 lon: 123.43278 hasResults: False
nctId: NCT06354296 id: CAF2024 briefTitle: Comparison of the Accuracy of Different Intraocular Lens Power Calculation Formulas in Cataract Patients With Prior Radial Keratotomy overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2024-08-15 date: 2024-08-31 date: 2024-04-09 date: 2024-04-09 name: He Eye Hospital class: OTHER briefSummary: The Web-based Barret True K formula with no history formula has been proven to be a good choice for cataract patients after RK in several studies. The American society of cataract and refractive surgeons provides several IOL formulas for cataract patients who have undergone previous corneal refractive surgery. In cases where only IOL-Master data are available, Holladay 1 (Double-K) \[Holladay 1 (D-K)\] can be used for IOL power calculation in cataract patients with a history of RK. The traditional Haigis formula has also been shown to be effective for cataract patients after RK. To compare the accuracy of four intraocular lens (IOL) power calculation formulas in cataract patients after RK. They are Barrett True-K formula, Holladay 1(D-K) formula, Haigis formula, and MM formula. conditions: Cataract studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: RETROSPECTIVE count: 50 type: ESTIMATED measure: Accuracy of the IOL formula sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False