hackint0sh/New-Dataset huggingface dataset:
The investigators hypothesise that HDT15, applied in acute ischemic stroke patients with a large vessel occlusion, will improve collateral circulation, prolong the survival of the ischemic penumbra and improve the clinical benefit from mechanical thrombectomy compared with standard of care (usual positioning 0° to +30°). conditions: Acute Ischemic Stroke studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The DOWN-SUITE trial is a prospective, multicenter, proof of concept, randomised, controlled, open label, phase 2a/b clinical trial with blinded outcome assessment, comparing cerebral collateral status in patients with acute ischemic stroke due to middle cerebral artery occlusion (M1 segment) treated with in-hospital application of HDT15 (-10° to -15°) versus usual positioning (0° to +30°), before and during mechanical thrombectomy. primaryPurpose: TREATMENT masking: SINGLE maskingDescription: A blinded central imaging core lab, whose members will be unaware of the procedure assignments, will assess all imaging outcomes, including the primary efficacy outcome (collateral status, assessed during the pretreatment diagnostic angiographic series of mechanical thrombectomy) whoMasked: OUTCOMES_ASSESSOR count: 118 type: ESTIMATED name: HEAD DOWN TILT -10° to -15° measure: Good collateral status measure: Feasibility of HDT15 measure: Delay to thrombectomy measure: Vomiting measure: Early neurological deterioration measure: Symptomatic intracranial hemorrhage measure: Aspiration pneumonia measure: Neurological disability measure: Systolic blood pressure measure: Diastolic blood pressure measure: Oxygen saturation sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06297850 id: WARD-Glucose Validation v.2.2 briefTitle: Accuracy of Continuous Glucose Monitoring in Patients With Diabetes. A Prospective Observational Study overallStatus: RECRUITING date: 2024-04-01 date: 2024-09-30 date: 2025-05-01 date: 2024-03-07 date: 2024-04-12 name: University Hospital Bispebjerg and Frederiksberg class: OTHER name: Rigshospitalet, Denmark name: Steno Diabetes Center Copenhagen name: Zealand University Hospital briefSummary: The goal of this observational study is to investigate the accuracy of the continuous glucose monitoring (CGM) compared to standard point-of-care (POC) blood glucose measurements in patients with diabetes in patients who during their hospital admission can experience circulatory impairment.
Participants will be asked to wear a blinded CGM device (Dexcom G7, Dexcom Inc.) during their stay in the hospital but will receive standard care of their diabetes. The CGM device will be worn for up to 10 days. conditions: Diabetes Mellitus conditions: Dysglycemia conditions: Perioperative Complication conditions: Circulatory; Complications studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 80 type: ESTIMATED name: Dexcom G7 Continuous Glucose Monitoring (CGM) System (G7) measure: Agreement between glucose measure: Agreement between glucose readings when at low glucose levels measure: Agreement between glucose readings when at normal glucose levels measure: Agreement between glucose readings when at high glucose levels measure: Adverse clinical outcomes measure: Readmission measure: Mortality sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Anaesthesiology, Centre for Cancer and Organ Diseases, Rigshospitalet status: RECRUITING city: Copenhagen state: The Capital Region Of Denmark zip: 2100 country: Denmark name: Eske K Aasvang, MD, DMSc role: CONTACT email: eske.kvanner.aasvang.01@regionh.dk lat: 55.67594 lon: 12.56553 facility: Department of Anaesthesiology and Intensive Care, Bispebjerg Hospital status: RECRUITING city: Copenhagen state: The Capital Region Of Denmark zip: 2400 country: Denmark name: Christian S Meyhoff, MD, PhD role: CONTACT email: christian.sylvest.meyhoff@regionh.dk lat: 55.67594 lon: 12.56553 facility: Department of Orthopaedic Surgery and Traumatology, Bispebjerg and Frederiksberg Hospital status: RECRUITING city: Copenhagen state: The Capital Region Of Denmark zip: 2400 country: Denmark name: Henrik Palm, MD, DMSc role: CONTACT email: henrik.palm@regionh.dk lat: 55.67594 lon: 12.56553 facility: Surgical department, Bispebjerg and Frederiksberg Hospital, status: NOT_YET_RECRUITING city: Copenhagen state: The Capital Region Of Denmark zip: 2400 country: Denmark name: Lars N Jørgensen, MD, DMSc role: CONTACT email: lars.nannestad.joergensen@regionh.dk lat: 55.67594 lon: 12.56553 hasResults: False
nctId: NCT06297837 id: LHS0205 briefTitle: ADAPT-AST (Adaptive Antimicrobial Susceptibility Testing) acronym: ADAPT-AST overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-12 date: 2026-03 date: 2024-03-07 date: 2024-03-07 name: Liverpool University Hospitals NHS Foundation Trust class: OTHER_GOV briefSummary: The goal of this study is to improve the way urinary tract infections (UTIs) are tested for antibiotic resistance. The main questions it aims to answer are:
Assessing whether it can help save money and resources in the lab and pharmacy. conditions: Urinary Tract Infections studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: RETROSPECTIVE count: 500000 type: ESTIMATED measure: The number of antimicrobial susceptibility results that 'should' spur action by a clinician on measure: The number of days until a result that 'should' spur action by a clinician measure: The number of antimicrobial susceptibility results that 'could' spur action by a clinician on measure: The number of days until a result that 'could' spur action by a clinician measure: The projected health economic cost per specimen, including laboratory (e.g., consumable cost) and patient (e.g., drug toxicity, clinical failure) measures. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT typeAbbrev: Prot_ICF hasProtocol: True hasSap: False hasIcf: True label: Study Protocol and Informed Consent Form date: 2023-10-03 uploadDate: 2023-11-16T04:00 filename: Prot_ICF_000.pdf size: 2230025 hasResults: False
nctId: NCT06297824 id: 2023-04909-01 briefTitle: Feasibility of Emotion Regulation Group Therapy for Adolescent Self-Harm acronym: ERGT-A overallStatus: RECRUITING date: 2023-10-10 date: 2024-12-31 date: 2025-06-30 date: 2024-03-07 date: 2024-03-07 name: Karolinska Institutet class: OTHER briefSummary: Deliberate self-harm (DSH) is a prevalent behaviour among adolescents but there is no current recommendation for an efficacious treatment. Emotion regulation group therapy (ERGT) is a brief treatment for DSH with a well-documented utility and feasibility in the adult population, and an adapted version for adolescents may provide equal benefits for adolescents, provided adjustments to prevent or decrease social contagion are present.
A quantitative feasibility open trial (N=20) followed up by a qualitative interview study will examine the feasibility, acceptability and preliminary effect of ERGT for adolescents. conditions: Self-harm conditions: Emotion Regulation conditions: Adolescent - Emotional Problem studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Feasibility, open trial primaryPurpose: TREATMENT masking: NONE count: 20 type: ESTIMATED name: ERGT-A measure: Feasibility measure, recruitment rate measure: Feasibility measures, proportion included measure: Feasibility measures, compliance measure: Feasibility measures, attrition measure: Feasibility measures, client satisfaction measure: Feasibility measures, negative effects of treatment measure: Preliminary effect, self harm frequency EOT measure: Preliminary effect, self harm frequency 1MFU measure: Preliminary effect, emotion dysregulation EOT measure: Preliminary effect, emotion dysregulation 1MFU sex: ALL minimumAge: 13 Years maximumAge: 17 Years stdAges: CHILD facility: Prima Barn och Vuxenpsykiatri Handen och Järva status: RECRUITING city: Stockholm state: Spånga zip: 16374 country: Sweden name: Dimitar Krastev, MSc role: CONTACT phone: +46735269516 email: Dimitar.Krastev@prima.se name: MaiBritt Giacobini, PhD role: CONTACT phone: +46709736662 email: Maibritt.Giacobini@prima.se lat: 59.33258 lon: 18.0649 hasResults: False
nctId: NCT06297811 id: SMA PT 001 briefTitle: Myeloprotection With Trilaciclib in Pan-cancer Population overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-09-30 date: 2027-12-31 date: 2024-03-07 date: 2024-03-07 name: Sun Yat-sen University class: OTHER briefSummary: The goal of this open-label randomized controlled study is to assess the myeloprotective effect of trilaciclib in pan-cancer population. The main questions it aims to answer are:
Participants will be randomized 2:1 to the treatment arm of trilaciclib in combination with a paclitaxel and carboplatin-based regimen and the control arm of a paclitaxel and carboplatin-based regimen for at least 6 cycles or until disease progression or intolerable toxicity. Patients in both groups could extend the chemotherapy cycle at the investigator 's discretion depending on the tumor type and in combination with anti-angiogenic/PD-X/anti-HER2 therapy. conditions: Non-Small Cell Lung Cancer conditions: Breast Cancer conditions: Endometrial Cancer conditions: Cervical Cancer conditions: Head And Neck Squamous Cell Carcinomas studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 132 type: ESTIMATED name: Trilaciclib Injection name: Paclitaxel name: Carboplatin measure: Occurrence of grade 3/4 neutropenia within 6 cycles sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Medical Oncology,Sun Yat-sen University Cancer Center city: Guangzhou state: Guangdong zip: 510060 country: China lat: 23.11667 lon: 113.25 hasResults: False
nctId: NCT06297798 id: SakaryaAppliedSciencesUPNS briefTitle: Effects of Telerehabilitation-Based Interventions on the Musculoskeletal System in Drivers overallStatus: NOT_YET_RECRUITING date: 2024-03-14 date: 2024-03-21 date: 2024-05-10 date: 2024-03-07 date: 2024-03-15 name: Sakarya Applied Sciences University class: OTHER briefSummary: This study is designed to examine the effect of telerehabilitation application on the musculoskeletal system of drivers.The study will include 40 voluntary participants who work as drivers on inter-district routes in Sakarya. The participants' sociodemographic information, musculoskeletal problems, and postures will be assessed. Participants will be divided into two groups: one group will receive tele-rehabilitation with posture and stabilization exercises, while the other group will serve as the control group. The exercises will be implemented for 10 weeks, followed by an 8-week tapering period, after which the groups will be crossed over. A re-evaluation will be conducted after 10 weeks, with follow-up assessments scheduled for 3 months later. conditions: Drive conditions: Musculoskeletal Diseases conditions: Postural; Defect studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: Telerehabilitation measure: MUSCLE SKELETAL SYSTEM ASSESSMENT measure: Posture Measures sex: MALE minimumAge: 30 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sakarya University of Applied Sciences city: Sakarya zip: 54000 country: Turkey name: Nurgul SEN, Master's degree role: CONTACT phone: 05344527440 email: pakizesen@subu.edu.tr name: Ceyhun TURKMEN, Assoc. Prof. role: PRINCIPAL_INVESTIGATOR hasResults: False
nctId: NCT06297785 id: 2022-03997-01 briefTitle: Online, Gut-directed Hypnotherapy for Patients With Irritable Bowel Syndrome (IBS) overallStatus: RECRUITING date: 2022-10-17 date: 2027-04 date: 2027-04 date: 2024-03-07 date: 2024-03-07 name: Sahlgrenska University Hospital, Sweden class: OTHER briefSummary: Adult IBS patients with symptoms refractory to standard medical treatment will receive online nurse-administered, gut-directed hypnotherapy in groups. The primary outcome measure was change in gastro-intestinal symptom severity. conditions: IBS - Irritable Bowel Syndrome studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 50 type: ESTIMATED name: Gut-directed hypnotherapy measure: Change in gastrointestinal symptom severity sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mag-Tarmlab, Sahlgrenska University Hospital status: RECRUITING city: Gothenburg zip: 41345 country: Sweden name: Jenny Lövdahl role: CONTACT phone: 0313428107 email: magtarmlab.su@vgregion.se lat: 57.70716 lon: 11.96679 facility: Sahlgrenska University Hospital status: RECRUITING city: Gothenburg zip: 41345 country: Sweden lat: 57.70716 lon: 11.96679 hasResults: False
nctId: NCT06297772 id: RJBMT-003 briefTitle: Compare the Efficacy and Safety of Dec-FB4 and FB4 as Conditioning Regimen for AML-MR overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-03-01 date: 2028-05-01 date: 2024-03-07 date: 2024-03-13 name: Ruijin Hospital class: OTHER briefSummary: A multicenter, randomized, controlled clinical study comparing the efficacy and safety of allogeneic hematopoietic stem cell transplantation with decitabine-Fludarabine- busulfan (Dec-FB4) and Fludarabine-busulfan (FB4) as pretreatment regimens for the treatment of acute myeloid leukemia in adults with MR gene abnormalities conditions: AML, Adult studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 220 type: ESTIMATED name: Decitabine name: Fludarabine Injection name: Busulfan Injection measure: disease-free survival measure: incidence of relapse rate measure: Non-recurrent mortality sex: ALL minimumAge: 16 Years maximumAge: 65 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Ruijin Hospital city: Shanghai zip: 200025 country: China name: Xiaoxia Hu role: CONTACT phone: 862164370045 email: hxx12276@rjh.com.cn lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06297759 id: ATADEK-2023/16 briefTitle: The Validity and Reliability Study of Turkish Version of the Sense of Competence in Dementia Care Staff (SCIDS) Scale overallStatus: NOT_YET_RECRUITING date: 2024-03-10 date: 2024-07 date: 2024-09 date: 2024-03-07 date: 2024-03-07 name: Yeditepe University class: OTHER name: Acibadem University briefSummary: The purpose of the study is to adapt the SCIDS into the Turkish version and validate it in the social and cultural context of Turkey to assess staff competency in dementia care in the long-term care setting. conditions: Dementia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 80 type: ESTIMATED name: Questionnaire measure: Sense of Competence in Dementia Care Staff (SCIDS) Scale measure: Caring Behaviors Inventory-24 sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06297746 id: am7mi3VB briefTitle: Subvastus vs. Medial Parapatellar Approaches in Total Knee Arthroplasty With Quadriceps Muscle Elastography overallStatus: COMPLETED date: 2023-07-10 date: 2023-12-01 date: 2023-12-01 date: 2024-03-07 date: 2024-03-08 name: Istanbul University - Cerrahpasa (IUC) class: OTHER briefSummary: ABSTRACT
Knee osteoarthritis is a common joint pathology causing joint pain and ambulatory limitations. In primary total knee arthroplasty (TKA) surgeries, medial parapatellar (MP) and subvastus (SV) approaches are frequently used. The MP approach provides good exposure and is more widely used. In the SV approach, the vastus medialis muscle is preserved. Some argue that the extensor mechanism may heal earlier with the SV approach. In this study, unlike previous studies, the investigators aimed to quantitatively compare the early outcomes of MP and SV approaches, through shear wave elastography (SWE) measurements isolated over the vastus medialis and vastus lateralis muscles.
The study included 20 patients with indications for TKA due to primary osteoarthritis, divided into MP and SV groups. SWE measurements of the vastus medialis and vastus lateralis muscles were performed preoperatively and at 3-month follow-up. Clinical scores (Knee Society Score and WOMAC) and straight leg raising time were recorded both preoperatively and postoperatively. conditions: Total Knee Arthroplasty studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 20 type: ACTUAL name: Subvastus approach name: Medial Parapatellar approach measure: Shear wave values sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Istanbul University - Cerrahpasa, Cerrahpasa Faculty of Medicine city: Istanbul state: Fatih zip: 34098 country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06297733 id: IstanbulBUFC3 briefTitle: Turkish Adaptation, Validity and Reliability of the Approaches and Study Skills Inventory in Physiotherapy Students overallStatus: RECRUITING date: 2024-04-01 date: 2024-06-01 date: 2024-07-01 date: 2024-03-07 date: 2024-04-16 name: Istanbul Bilgi University class: OTHER briefSummary: The quality and quantity of learning are determined by the learning approach adopted by the student. When learning and studying approaches are mentioned, individual differences between learners' learning intentions during a learning situation or while studying and what types of strategies are used to achieve these intentions come to mind. These learning approaches are thought to determine the quality of learning outcomes. Many measurement tools have been developed to quantitatively measure learning and studying approaches. These developed tools are mostly applied at the higher education level. Among the purposes of using measurement tools; These include identifying low-performing students through screening, evaluating and identifying areas of difficulty that require prediction or improvement plans, evaluating before and after academic improvement programs, and raising awareness and advising students on their academic strengths and weaknesses.
The Portuguese, Norwegian and Danish versions of the survey, which was developed in English and intended to be translated into Turkish as the Study Skills and Approaches Scale, have also been translated, its psychometric properties have been demonstrated and it has been observed that it is becoming widespread in the literature. conditions: Health Education studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 260 type: ESTIMATED name: Translating the Questionnaire into Turkish and Related Processes name: Validity name: Reliability measure: Approaches and Study Skills Inventory for Students measure: Participant Information Form sex: ALL minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT facility: Marmara University status: RECRUITING city: Istanbul zip: 34854 country: Turkey name: Ilksan Demirbuken, Prof role: CONTACT phone: 2167775701 phoneExt: +90 email: ilksan.demirbuken@marmara.edu.tr lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06297720 id: 2401110013 briefTitle: Early Oral Hydration After Thoracoscopic Surgery overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-02-28 date: 2025-06-30 date: 2024-03-07 date: 2024-03-07 name: Chang Gung Memorial Hospital class: OTHER briefSummary: The goal of this clinical trial is to learn about the safety and feasibility of early oral hydration in patients receiving video-assisted thoracoscopic surgery after general anesthesia. The main questions aims to answer:
Participants will receive a series of oral hydration from swab moistening, and ice cube hydration to water hydration in the recovery room. Researchers will compare with the standard, no-hydration group to see if it is safe and feasible to hydrate patients in the recovery room. conditions: Anesthesia conditions: Intubation Complication studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 120 type: ESTIMATED name: Oral hydration measure: sore throat level by VAS (Visual Analogue Scale) measure: Mouth dryness measure: post-operative nausea and vomiting (PONV) measure: timing of post-operative nausea and vomiting (PONV) measure: duration of post-operative nausea and vomiting (PONV) measure: management of post-operative nausea and vomiting (PONV) measure: Heart Rate in PACU (Postanesthesia Care Unit) measure: Blood pressure in PACU (Postanesthesia Care Unit) measure: Patient's satisfaction sex: ALL minimumAge: 20 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: ChangGung MH city: Taoyuan zip: 33380 country: Taiwan name: JUN-YU CHEN role: CONTACT lat: 24.95233 lon: 121.20193 hasResults: False
nctId: NCT06297707 id: P.T.REC/012/005044 briefTitle: Effect of Aquatic High Intensity Resistive Training on Patients With Chronic Heart Failure overallStatus: RECRUITING date: 2024-03-05 date: 2025-03-30 date: 2025-12-30 date: 2024-03-07 date: 2024-03-07 name: Cairo University class: OTHER briefSummary: PURPOSE:
Heart failure (HF) is a rapidly growing public health issue with an estimated prevalence of \>37.7 million individuals globally. HF is a shared chronic phase of cardiac functional impairment secondary to many etiologies, and patients with HF experience numerous symptoms that affect their quality of life, including dyspnea, fatigue, poor exercise tolerance, and fluid retention. conditions: Heart Failure studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: aquatic high intensity resistive training name: usual care measure: Cardiac function measure: exercise capacity measure: physical symptoms of heart failure sex: ALL minimumAge: 45 Years maximumAge: 60 Years stdAges: ADULT facility: Faculty of Physical Therapy status: RECRUITING city: Cairo state: Dokki zip: 11432 country: Egypt name: marwa M elsayed, phd role: CONTACT phone: 01156033818 phoneExt: 02 email: marwadd999@gmail.com name: marwa M elsayed, ph.d role: CONTACT phone: 01156033818 phoneExt: 02 email: marwadd999@gmail.com lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06297694 id: PamukkaleU. briefTitle: Clinical Interpretation and Cutoff Scores for ABILHAND Questionnaire in Rheumatoid Arthritis overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-06 date: 2024-07 date: 2024-03-07 date: 2024-03-07 name: Pamukkale University class: OTHER briefSummary: In individuals with rheumatoid arthritis, the most significant symptom is the loss of manual ability and function in the hands. In rheumatoid arthritis, where patient-reported assessment scales are frequently used, hand skills should be evaluated with an ideal questionnaire that best represents hand activities. The ABILHAND-RA questionnaire possesses all these features, being a short and easily fillable survey. The aim is to determine of clinically significant cutoff scores for perceived manual ability evaluated by ABILHAND corresponding to observed and perceived upper extremity assessments in individuals with rheumatoid arthritis. conditions: Rheumatoid Arthritis studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 156 type: ESTIMATED measure: Disease Activity Score (DAS 28) measure: Nine hole peg test measure: Hand grip strength sex: ALL minimumAge: 20 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False