hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06284174 id: B-BR-109-054-T briefTitle: Effectiveness of Povidone-Iodine Versus Chlorhexidine Gluconate Solutions in Reducing Microbial Contamination in Spinal Surgery Wounds During Intraoperative Soaking. overallStatus: RECRUITING date: 2021-01-01 date: 2024-12-31 date: 2024-12-31 date: 2024-02-28 date: 2024-02-28 name: National Cheng-Kung University Hospital class: OTHER briefSummary: This study aims to assess the efficacy of intraoperative wound irrigation with iodine-containing and chlorhexidine-containing solutions in reducing bacterial colonization during spine surgery, and to determine which solution is more effective. Additionally, we aim to evaluate any side effects associated with the use of these two antiseptic solutions for wound irrigation. conditions: Spine Infection studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: This research will include patients diagnosed with lumbar spinal stenosis causing nerve compression, who are scheduled for open spinal decompression and fusion surgery. Patients will be randomly assigned to one of three groups: a control group (soaked with 0.9% normal saline), an iodine group (soaked with 3.5% povidone-iodine solution), and a CHG group (soaked with 0.05% chlorhexidine gluconate). All groups will receive the same surgical pre-care, preoperative disinfection, and prophylactic antibiotics. Before wound closure, each group will undergo different irrigation solutions for soaking the wound for three minutes followed by rinsing with copious saline. Samples from deep and superficial tissues and implants will be taken for bacterial culture and molecular biochip analysis. primaryPurpose: PREVENTION masking: DOUBLE maskingDescription: Patients will be randomly assigned by computer to one of three groups: a control group (soaked with 0.9% normal saline), an iodine group (soaked with 3.5% povidone-iodine solution), and a CHG group (soaked with 0.05% chlorhexidine gluconate). All groups will receive the same surgical pre-care, preoperative disinfection, and prophylactic antibiotics.
All patients understood the experimental process and signed the consent form. The patients did not know the group they were assigned to during the whole process. The bacterial culturers, examiners and clinical outcome assessors did not know the patient group. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 105 type: ESTIMATED name: Povidone-iodine solution; chlorhexidine gluconate measure: Bacteria culture and Polymerase chain reaction exam measure: Post operative infection sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: National Cheng Kung University Hospital status: RECRUITING city: Tainan zip: 704 country: Taiwan name: Wei-Ren Su, M.D., M.Sc. role: CONTACT phone: 886-6-2766689 email: suwr@ms28.hinet.net lat: 22.99083 lon: 120.21333 hasResults: False
nctId: NCT06284161 id: RBHP 2020 GUY id: 2020-A02765-34 type: OTHER domain: ANSM briefTitle: QCT in ALS Diagnosis, Mechanistic Understanding and Follow-up acronym: PEM-SLA overallStatus: RECRUITING date: 2022-06-28 date: 2025-06-28 date: 2026-02-28 date: 2024-02-28 date: 2024-02-28 name: University Hospital, Clermont-Ferrand class: OTHER briefSummary: Multidisciplinary management of amyotrophic lateral sclerosis (ALS) can significantly increase survival but also improve the quality of life of patients. The evaluation of cortical-spinal motor neuron damage is currently based only on the assessment of clinical data. However, the alteration of the central motor pathway and conduction can be identified and quantified by different techniques using motor-evoked potentials (MEP). The combined quadriceps test (QCT) has been developed to assess central and peripheral motor pathway conduction. This test allows to quantify central and peripheral part of a mixed disorder, and to detect physiological hyporeflexia or hyperreflexia which, in the case of suspected ALS, can lead to interpretation problems.
The evolution of the QCT parameters during the course of pathology will lead to determine the preponderance of an initial central involvement, but also its extension throughout the pathology. The study of these parameters as well as the clinical course of the disease could reveal a correlation between peripheral and central involvement. This link would provide arguments in favor of pathophysiological hypotheses of disease onset and progression. From a prognostic point of view and depending on the quantification of central and peripheral involvement, the QCT would make it possible to characterize the different ALS phenotypes. This phenotypic characterization would help identify prognostic factors at diagnosis.
nctId: NCT06284148 id: Pro00093964 id: 5R18HS025654-03 type: AHRQ link: https://reporter.nih.gov/quickSearch/5R18HS025654-03 briefTitle: Confidential IPV Screening Tool overallStatus: COMPLETED date: 2010-10-06 date: 2023-07-31 date: 2023-07-31 date: 2024-02-28 date: 2024-02-28 name: Medical University of South Carolina class: OTHER name: Agency for Healthcare Research and Quality (AHRQ) briefSummary: Intimate partner violence (IPV) against women in the US is a serious public health problem and a human rights issue. Our research team has developed confidential screening tools using exam-room computer for intimate partner violence to be used in primary care. conditions: Violence, Domestic studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: This is a stepped wedge cluster randomized trial which has 3 sequences starting intervention in randomized order. primaryPurpose: SCREENING masking: NONE count: 19655 type: ACTUAL name: Screening for intimate partner violence name: Assessment and referral measure: IPV positive (Yes/No) measure: Screening completed (Yes/No) measure: Severity of risk measure: Physician compliance with IPV management tools sex: ALL minimumAge: 18 Years maximumAge: 49 Years stdAges: ADULT facility: Biomedical Informatics Center city: Charleston state: South Carolina zip: 29403 country: United States lat: 32.77657 lon: -79.93092 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2023-12-01 uploadDate: 2024-02-20T12:06 filename: Prot_SAP_000.pdf size: 179261 hasResults: False
nctId: NCT06284135 id: 2017-PS-03 id: PV6099 type: OTHER domain: Martini-Klinik briefTitle: MICHL-trial: Impact of Peritoneal Bladder Flap in RARP Patients on Lymphoceles overallStatus: COMPLETED date: 2017-06-19 date: 2019-10-16 date: 2021-05-31 date: 2024-02-28 date: 2024-02-28 name: Martini-Klinik am UKE GmbH class: OTHER briefSummary: A two-armed prospective randomised, controlled, single-centre trial on 1080 patients with prostate cancer who underwent robot-assisted radical prostatectomy with bilateral pelvic lymph node dissection was carried out. Patients in the intervention arm received fixation of the peritoneal flap of the bladder to the plexus Santorini at the end of surgery (Michl-technique, MT); in the control group, surgery was performed without this modification. The primary endpoint was the rate of lymphoceles requiring intervention. conditions: Lymphocele After Surgical Procedure studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: SINGLE whoMasked: PARTICIPANT count: 1080 type: ACTUAL name: Michl-stitch measure: rate of lymphoceles requiring intervention after RARP measure: total lymphocele rate after RARP measure: other complications ≥ grade IIIa according to Clavien-Dindo after RARP measure: continence rates after RARP sex: MALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Martini-Klinik am UKE GmbH city: Hamburg zip: 20246 country: Germany lat: 53.57532 lon: 10.01534 hasResults: False
nctId: NCT06284109 id: 23-1036 briefTitle: Preoperative (Pre-amputation) Cryoanalgesia to Improve Post-amputation Phantom Limb Pain overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-12-31 date: 2024-12-31 date: 2024-02-28 date: 2024-04-23 name: The Cleveland Clinic class: OTHER name: Pacira Pharmaceuticals, Inc briefSummary: Investigators will evaluate preamputation cryoanalgesia on pain, mobility, opioid use and general physical and emotional disability using a pilot randomized trial design, to explore the amount and variability of improvement on those outcomes and to investigate the potentiality of conducting a future larger randomized controlled trial, which the investigators will assess quantitatively the benefits of cryoanalgesia. conditions: Postoperative Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Pre-Operative Patients will receive cryoanalgesia or sham cryoanalgesia before amputation. primaryPurpose: TREATMENT masking: TRIPLE maskingDescription: All participants will receive nerve blocks with Local anesthetic. Participants will be Randomized on a 1:1 fashion to cryoanalgesia or sham cryoanalgesia, based on computer-generated codes and use random-sized blocks. Patients will not be told which group they are in. whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 20 type: ESTIMATED name: Cryoanalgesia name: Sham Cryoanalgesia measure: Phantom limb pain score measure: Mobility measure: General physical and emotional disability measure: Opioid consumption measure: Residual limb pain sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06284096 id: 2023/391 briefTitle: The Personal Recovery Based Psychoeducation For Schizophrenia overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2024-06 date: 2024-06 date: 2024-02-28 date: 2024-03-07 name: Istanbul University - Cerrahpasa (IUC) class: OTHER briefSummary: This project aims to introduce a new psychoeducation program that helps individuals with schizophrenia to recover subjectively. The program's effectiveness will be evaluated through a randomized controlled research design. The goal is not only to emphasize clinical recovery but also to highlight the importance of individual recovery and promote its implementation. In this context, the following hypotheses have been formulated.
H1c: Recovery-based psychoeducation has an effect on hope in individuals diagnosed with schizophrenia in remission. conditions: Mental Health Recovery conditions: Schizophrenia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 60 type: ESTIMATED name: Psychoeducation measure: Personal Recovery levels of individuals diagnosed with schizophrenia measure: Psychological resilience levels of individuals diagnosed with schizophrenia measure: Hope levels of individuals diagnosed with schizophrenia sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Umraniye Community Mental Health Center affiliated with the Ministry of Health. city: Istanbul state: Umraniye zip: 34760 country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06284083 id: Cumhuriyet University Hospital briefTitle: Measuring Various Variables in Obstructive Sleep Apnea acronym: OUAS overallStatus: COMPLETED date: 2018-12-18 date: 2021-01-15 date: 2022-02-07 date: 2024-02-28 date: 2024-02-28 name: Cumhuriyet University class: OTHER briefSummary: This study included 90 volunteer Obstructive Sleep Apnea Syndrome patients. Only 7 mL blood samples collected from patients. Some biochemicals parameters analyzed in blood serum/plasma. conditions: Obstructive Sleep Apnea-hypopnea Syndrome studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The study group consisted of 90 newly diagnosed OSAS patients who were admitted to the Clinic for Chest Diseases of the Research and Practice Hospital of Sivas Cumhuriyet University Faculty of Medicine. For the definitive diagnosis of OSAS, the patients were hospitalized overnight in the Sleep Center and polysomnography test was performed. OSAS patients, who were randomly selected without discrimination in terms of age and gender, were connected to the PSG device for one night and various measurements were taken and the values were recorded. The apnea/hypopnea index (AHI) was defined as the sum of the apnea and hypopnea number per hour of sleep. Volunteer patients were grouped into three based on apnea-hypopnea index (AHI) scores: mild OSAS (n=30; 5 ≤ AHI ≤ 13.70), moderate (n=30; 15.80 ≤ AHI ≤ 26.60) and severe (n=30; 34.10 ≤ AHI ≤ 86.30). The mean SpO2 percentages of the PSG device were measured from the fingertip with a system-defined pulse oximeter. primaryPurpose: HEALTH_SERVICES_RESEARCH masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 90 type: ACTUAL name: taking a blood sample measure: Agmatine, telomerase and trace element levels in blood serum vary depending on disease severity. measure: Polysomnographic measurement sex: ALL minimumAge: 18 Years maximumAge: 74 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sivas Cumhuriyet University city: Sivas state: Centre zip: 58140 country: Turkey lat: 39.74833 lon: 37.01611 hasResults: False
nctId: NCT06284070 id: 202433 briefTitle: Application of FAPI and FDG PET Imaging in Patients With Different Types of Cancer overallStatus: RECRUITING date: 2024-01-01 date: 2029-12-31 date: 2029-12-31 date: 2024-02-28 date: 2024-02-28 name: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University class: OTHER briefSummary: Cancer associated fibroblasts (CAFs) can promote tumor cell proliferation, migration, invasion, and angiogenesis through immunosuppressive effects and the production of mediators, thereby promoting tumor growth and progression. The characteristic of CAFs is high expression of fibroblast activation protein (FAP). In approximately 90% of epithelial derived tumors, FAP is highly overexpressed on the membrane of CAFs. Contrary to CAFs, FAP expression is lower or absent in normal tissues. Therefore, FAP inhibitors (FAPI) targeting FAP can overcome the limitations of 18F-2-fluoro.2-deoxy-D-glucose fluorodeoxyglucose(18F-FDG) PET imaging. But like 18F-FDG, wound healing, fibrosis, and inflammation can also uptake FAPI.. Therefore, a comparison of the performance of 18F-FDG and 18F-FAPI PET imaging in diagnosing primary and metastatic lesions of various types of cancer is conducted to evaluate the potential value of these new radiopharmaceuticals as effective alternatives to 18F-FDG, highlighting their advantages and limitations. conditions: Cancer studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 2000 type: ESTIMATED measure: Diagnostic efficacy measure: SUV sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Nuclear Medicine, Daping Hospital of Army Medical University status: RECRUITING city: Chongqing state: Chongqing zip: 400010 country: China name: Xiao Chen, Ph.D role: CONTACT phone: 15922970174 email: xiaochen229@foxmail.com name: Xiao Chen, Ph.D role: PRINCIPAL_INVESTIGATOR name: Jinju Sun, MSc role: PRINCIPAL_INVESTIGATOR lat: 29.56278 lon: 106.55278 hasResults: False
nctId: NCT06284057 id: CopperHealthCentre3 briefTitle: Lower Silesia Culotte Bifurcation Registry (LSCBR). acronym: LSCBR overallStatus: RECRUITING date: 2013-04-01 date: 2028-04-01 date: 2028-04-01 date: 2024-02-28 date: 2024-03-06 name: Regional Cardiology Center, The Copper Health Centre (MCZ), class: OTHER name: Department of Cardiology, Provincial Specialized Hospital in Legnica, 59-200 Legnica, Poland. briefSummary: The study aimed to evaluate the outcomes of bifurcation PCI using two techniques (Culotte vs. DK-Culotte) using data from a retrospective analysis. conditions: Safety Issues conditions: Efficacy, Self studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 400 type: ESTIMATED name: Bifurcation PCI with two stent technique Culotte Technique or Double Kiss (DK) Culotte measure: Target lesion failure (TLF) measure: MACE measure: Stent thrombosis measure: Stent restenosis sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Cardiology, Provincial Specialized Hospital in Legnica, status: RECRUITING city: Legnica state: Lower Silesia zip: 59-220 country: Poland name: Mateusz Barycki, M.D role: CONTACT phone: +48767211446 email: mateusz.barycki@gmail.com name: Piotr Rola, M.D. Ph.D role: CONTACT phone: +48767211446 email: piotr.rola@gmail.com name: Mateusz Barycki, MD role: PRINCIPAL_INVESTIGATOR name: Piotr Rola, MD PhD role: SUB_INVESTIGATOR lat: 51.21006 lon: 16.1619 facility: Department of Cardiology, The Copper Health Centre (MCZ) status: RECRUITING city: Lubin state: Lower Silesia zip: 59-300 country: Poland name: Adrian Włodarczak, Assoc Prof. role: CONTACT phone: +48768460300 email: wlodarczak.adrian@gmail.com name: Szymon Włodarczak, MD role: CONTACT phone: +4876 846 03 00 email: wlodarczak.szy@gmail.com name: Adrian Włodarczak, Assoc Prof. role: PRINCIPAL_INVESTIGATOR name: Szymon Włodarczak, MD role: SUB_INVESTIGATOR lat: 51.40089 lon: 16.20149 hasResults: False
nctId: NCT06284044 id: NIHR204885 briefTitle: Facilitating Safe Transition to Home for Preterm Infants - a National Database Study overallStatus: RECRUITING date: 2023-12-01 date: 2024-11-30 date: 2024-11-30 date: 2024-02-28 date: 2024-03-27 name: University Hospitals of Derby and Burton NHS Foundation Trust class: OTHER briefSummary: Preterm infants (i.e. born before 37 completed weeks of pregnancy) often require additional care and are admitted to neonatal units. Readiness for discharge home typically requires a level of physiological maturity, such that an infant is: 1) able to breathe spontaneously without additional support; 2) able to maintain body temperature; 3) able to take all nutritional requirements orally; 4) weighs ≥1700 grams and is consistently gaining weight.
This study will use data from babies' medical records from the whole of England and Wales to identify the age and postmenstrual age when preterm infants reach each of the physiological barriers to discharge and identify which physiological discharge barrier requires preterm infants to remain in hospital the longest. The study will quantify the difference between the time preterm infants become physiologically ready for discharge and actual discharge home and describe factors associated with extended stays. conditions: Premature Birth studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: OTHER count: 250000 type: ESTIMATED measure: Age and postmenstrual age when each of three physiological barriers are reached measure: Final barrier to discharge home measure: Number of days in hospital after surpassing all physiological discharge barriers sex: ALL minimumAge: 22 Weeks maximumAge: 36 Weeks stdAges: CHILD facility: University Hospitals of Derby and Burton status: RECRUITING city: Derby state: Derbyshire zip: DE22 3DT country: United Kingdom name: Janine Abramson, BSc Hon role: CONTACT phone: 01332 724690 email: janine.abramson@nottingham.ac.uk lat: 52.92277 lon: -1.47663 hasResults: False
nctId: NCT06284031 id: Brachy Study briefTitle: Cervical Cancer Brachytherapy With Interstitial Needles in 3 Fractions overallStatus: RECRUITING date: 2023-06-26 date: 2026-06 date: 2026-12 date: 2024-02-28 date: 2024-02-28 name: National University Hospital, Singapore class: OTHER briefSummary: Aim To determine the feasibility and safety of 3 fractions of high dose rate (HDR) brachytherapy with interstitial needles for cervical cancer in the outpatient setting
Secondary objective To determine the long-term toxicities of this regimen based on CTCAE v5 conditions: Cervical Cancer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 56 type: ESTIMATED name: 3 fractions HDR brachytherapy measure: Local control rate measure: Loco-regional control rate measure: Progression-free survival (PFS) measure: Overall survival (OS) measure: Long term toxicities sex: FEMALE minimumAge: 21 Years stdAges: ADULT stdAges: OLDER_ADULT facility: National University Hospital status: RECRUITING city: Singapore zip: 119074 country: Singapore name: Fatin Aliyah, BSc role: CONTACT phone: +6581005851 email: fatin_hussin@nuhs.edu.sg name: Syadwa Abdul Shukor, MD role: SUB_INVESTIGATOR name: Yiat Horng Leong, MD role: SUB_INVESTIGATOR name: Shing Fung Lee, MD role: SUB_INVESTIGATOR name: Michelle Tseng, MD role: SUB_INVESTIGATOR lat: 1.28967 lon: 103.85007 hasResults: False
nctId: NCT06284018 id: postnatal low back pain briefTitle: Effect of Progressive Muscle Relaxation Exercises Versus Pilates Exercises on Postnatal Low Back Pain overallStatus: NOT_YET_RECRUITING date: 2024-02-24 date: 2024-12-31 date: 2024-12-31 date: 2024-02-28 date: 2024-02-29 name: Cairo University class: OTHER briefSummary: This study was conducted to compare between the effect of progressive muscle relaxation exercises and the effect of pilates exercises on postnatal low back pain conditions: Low Back Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: intervention The design of the study was randomized controlled study. The patients were divided randomly into two equal groups (A\&B). Group A consisted of thirty postnatal women. They were treated by progressive muscle relaxation exercises three times per week for 4 weeks. Group B consisted of thirty postnatal women. They were treated by pilates exercises three times per week for 4 weeks. primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Progressive Muscle Relaxation Exercises name: Pilates Exercises measure: Pressure Algometer measure: Oswestry Disability Index sex: FEMALE minimumAge: 25 Years maximumAge: 35 Years stdAges: ADULT facility: faculty of physical therapy: Cairo university city: Giza zip: 12662 country: Egypt lat: 30.00808 lon: 31.21093 hasResults: False
nctId: NCT06284005 id: MOTU ATP - Studio clinico briefTitle: Multicentre Interventional Pilot Study on the Evaluation of the Functionality, Safety and Reliability of a New Robotic Prosthesis for the Lower Limb at the Transfemoral Level acronym: MOTU-ATP overallStatus: COMPLETED date: 2020-07-27 date: 2022-11-10 date: 2022-12-22 date: 2024-02-28 date: 2024-02-28 name: Fondazione Don Carlo Gnocchi Onlus class: OTHER briefSummary: The goal of this multicenter interventional pilot is to verify the functionality of a prosthesis for trans-femoral amputees.
* stair climbing/descent tests. conditions: Amputation conditions: Amputation; Traumatic, Leg, Lower studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DEVICE_FEASIBILITY masking: NONE count: 4 type: ACTUAL name: WRL ATP measure: ad hoc check-list Adverse Event measure: ad hoc check-list Adverse Event measure: ad hoc check-list Adverse Event measure: ad hoc check-list Adverse Event measure: ad hoc check-list Adverse Event sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS Fondazione Don Carlo Gnocchi city: Firenze state: FI zip: 50143 country: Italy lat: 43.77925 lon: 11.24626 hasResults: False