hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06322082 id: 1422024 briefTitle: Pilates Training and Low Intensity Shock Wave Therapy for Post-prostatectomy Stress Incontinence acronym: Incontinence overallStatus: ENROLLING_BY_INVITATION date: 2024-03-20 date: 2024-10-30 date: 2024-12-15 date: 2024-03-20 date: 2024-03-28 name: Khadra Mohamed Ali class: OTHER name: Cairo University briefSummary: 120 Patients with urinary incontinence following radical prostatectomy would be randomly assigned to either 4 groups all receive conventional pelvic floor muscle exercises plus group A receive Pilates exercises and Low Intensity Extracorporeal Shock Wave Therapy, group B receive Low Intensity Extracorporeal Shock Wave Therapy, group C receive Pilates exercises and group D receive conventional pelvic floor muscle exercises. Assessment at baseline, immediately after the intervention, to evaluate the degree of urinary incontinence and quality of life after three months from treatment. conditions: Stress Incontinence, Male studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 120 type: ESTIMATED name: The DUOLITH SD1-TOP focused shock wave system (STORZ MEDICAL AG) measure: Cystometry measure: Severity index scale measure: body mass index sex: MALE minimumAge: 40 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: faculty of physical therapy , Cairo university city: Giza country: Egypt lat: 30.00808 lon: 31.21093 hasResults: False
nctId: NCT06322069 id: 202206260077 briefTitle: The Effect and Mechanism of Self-compassion on Reducing Materialism overallStatus: COMPLETED date: 2020-12-14 date: 2021-03-03 date: 2021-03-15 date: 2024-03-20 date: 2024-03-20 name: Beijing Normal University class: OTHER briefSummary: The current study provided an initial investigation of the effect of self-compassion on reducing materialism and explored the basic psychological needs and self-esteem as potential mechanisms. Two studies would be conducted. Study 1 explored the relationships among variables with cross-sectional data, to explore the relationship between self-compassion and materialism, and test the mediating role of basic psychological needs and self-esteem. Study 2 developed a new online self-help self-compassion intervention and conducted a randomized control trial (i.e., intervention group and waitlist group) to further explore the casual effect of self-compassion on materialism, with the mediating effect of basic psychological needs and self-esteem. conditions: Self-Compassion conditions: Group B studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: In study 2, we conducted a randomized control trial, and there are two groups: self-compassion intervention group and waitlist group. primaryPurpose: OTHER masking: NONE count: 309 type: ACTUAL name: Self-compassion intervention group measure: Self-compassion measure: Self-Esteem measure: Basic Psychological Needs measure: Materialism sex: ALL minimumAge: 18 Years maximumAge: 63 Years stdAges: ADULT facility: Xianglong Zeng city: Beijing state: Beijing zip: 100875 country: China lat: 39.9075 lon: 116.39723 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2024-03-12 uploadDate: 2024-03-12T23:23 filename: Prot_SAP_000.pdf size: 110133 hasResults: False
nctId: NCT06322056 id: 4-2023-1654 briefTitle: Exploring Approaches With Lower Targets of Blood Pressure and Lipid for Improving Renal Outcome in Advanced Chronic Kidney Disease acronym: EXCELSIOR-CKD overallStatus: NOT_YET_RECRUITING date: 2024-05-13 date: 2029-05-31 date: 2029-08-31 date: 2024-03-20 date: 2024-03-20 name: Yonsei University class: OTHER briefSummary: The purpose of this study is to prevent kidney disease progression in adults with advanced chronic kidney disease (estimated glomerular filtration rate \[eGFR\] between 15-45 mL/min/1.73 m2) using intensive blood pressure control and intensive lipid management with 2X2 factorial design. conditions: Chronic Kidney Diseases conditions: Hypertension conditions: Dyslipidemias studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: NONE count: 642 type: ESTIMATED name: Intensive control of SBP and intensive control of LDL-C name: Intensive control of SBP and standard control of LDL-C name: Standard control of SBP and intensive control of LDL-C name: Standard control of SBP and standard control of LDL-C measure: Renal composite outcome measure: Individual components of renal composite outcome measure: eGFR slopes measure: Cardiovascular composite outcome sex: ALL minimumAge: 19 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Severance Hospital city: Seoul zip: 03722 country: Korea, Republic of lat: 37.566 lon: 126.9784 hasResults: False
nctId: NCT06322043 id: VM-APFB-1023 briefTitle: Evaluation of Safety of Filler Injection in Subcutaneous Tissues overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-09 date: 2025-04 date: 2024-03-20 date: 2024-03-20 name: Volumina Medical S.A. class: INDUSTRY briefSummary: Adipearl is an injectable filler intended to be injected subcutaneously. conditions: Volume Deficiency studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: BASIC_SCIENCE masking: NONE count: 18 type: ESTIMATED name: Adipearl measure: Safety of Investigational Medical Device sex: ALL minimumAge: 22 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Summit Clinic city: Crans-Montana country: Switzerland name: Summit Clinic role: CONTACT lat: 46.31316 lon: 7.47914 hasResults: False
nctId: NCT06322030 id: N4281-R id: RX004281 type: OTHER_GRANT domain: VA ORD RR&D id: PRO0120848 type: OTHER domain: IRB Approval briefTitle: Weight Loss and ExeRcise acronym: EMPOWER overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-12-31 date: 2028-03-31 date: 2024-03-20 date: 2024-04-25 name: VA Office of Research and Development class: FED briefSummary: Weight loss interventions for neurologically health individuals have established benefits for improving physical and psychosocial function. The investigators believe that Veterans who have had a stroke would realize similar benefits and that the effects would be enhanced with concurrent exercise training. The investigators will study the effects of a 15-week lifestyle management program to determine if it can effectively improve some of the physical and psychosocial problems common in Veterans who have had a stroke. conditions: Stroke studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The investigators will utilize a 2x2 factorial design to assess for changes in our outcomes over time between treatment groups. primaryPurpose: TREATMENT masking: SINGLE maskingDescription: The coordinator will not see group assignment, only a patient number which is entered into a software package. whoMasked: OUTCOMES_ASSESSOR count: 99 type: ESTIMATED name: FOCUS-15 Lifestyle Management Program name: Exercise Training measure: Change in distance walk in 6 minute Walk Test measure: Change in daily step activity measure: Change in score of Stroke Impact Scale (SIS) measure: Change in score of Sheehan Disability Scale (SDS) measure: Change in score of Inventory of Psychosocial Functioning (IPF) measure: Change in blood lipid profile measure: Change in body composition in Dual-energy x-ray absorptiometry sex: ALL minimumAge: 40 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ralph H. Johnson VA Medical Center, Charleston, SC city: Charleston state: South Carolina zip: 29401-5703 country: United States name: R. Amanda C LaRue, PhD role: CONTACT phone: 843-789-6707 email: Rutha.Larue@va.gov name: Thad Abrams, MD role: CONTACT phone: (319) 338-0581 phoneExt: 7618 email: thad.abrams@va.gov name: Chris M Gregory, PhD role: PRINCIPAL_INVESTIGATOR lat: 32.77657 lon: -79.93092 hasResults: False
nctId: NCT06322017 id: RC22_0450 briefTitle: Prospective Multicenter Randomized and Controlled Study Evaluating the Benefit of Early Pulmonary Vein Isolation Compared to Usual Treatment in Patients Aged Over 75 Years and Presenting With Atrial Fibrillation acronym: EDearly AF overallStatus: RECRUITING date: 2024-04-09 date: 2028-04-09 date: 2028-04-09 date: 2024-03-20 date: 2024-04-11 name: Nantes University Hospital class: OTHER briefSummary: Therapeutic management of Atrial Fibrillation (AF) is based either on heart rate control or on rhythm control, a strategy which aims to maintain a normal heart rhythm. The benefit in terms of morbidity and mortality of a normal heart rhythm would, however, be largely offset by the frequent side effects of antiarrhythmic drugs which could even lead to an increase in mortality compared to rate control. This increase has particularly been suggested in people aged over 75.
Since the emergence of catheter Pulmonary Vein Isolation (PVI), an effective alternative to antiarrhythmic drugs has become available. This technique makes it possible to isolate the foci triggering AF under local or general anesthesia with greater effectiveness than medications and very low risks. Records in the elderly do not seem to show a reduction in effectiveness or an increase in complications. However, in the absence of a dedicated randomized study, its use is strongly limited in the elderly where rate control (52% of people over 65 years old) and the use of antiarrhythmic drugs are largely favored due to the simplicity of implementation and the low cost of medications.
The objective of the investigator is therefore to carry out the first randomized comparative study proposing to evaluate the impact of early PVI compared to usual treatment in patients aged 75 and over with AF. conditions: Atrial Fibrillation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 294 type: ESTIMATED name: Rhythm control by Pulmonary Vein Isolation (PVI) procedure name: Conventional care by antiarrhythmic drugs (flecainide, sotalol, amiodarone) or bradycardic drugs (all betablocker or calcium channel blocker therapy, digoxin) measure: Time before occurrence of the first event among cardiovascular death, hospitalization (all causes) and stroke measure: Number of PVI peri-procedural complications measure: Number of complications measure: Quality of life score measure: Quality of life score measure: Quality of life score measure: Quality of life score measure: Quality of life score measure: Quality of life score measure: Number of documented episodes of AF measure: Number of patients treated by cardiovascular drugs measure: Doses of cardiovascular drugs measure: Autonomy score measure: Autonomy score measure: Autonomy score measure: Autonomy score measure: Autonomy score measure: Autonomy score measure: Autonomy score measure: Autonomy score measure: Autonomy score measure: Autonomy score measure: Autonomy score measure: Autonomy score measure: Body weight measure: Body weight measure: Body weight measure: Body weight measure: Body weight measure: Body weight measure: Numbers of falls measure: Numbers of falls measure: Numbers of falls measure: Numbers of falls measure: Numbers of falls measure: Numbers of falls measure: Physical performance score measure: Physical performance score measure: Evolution of ADL score according to the results of the Integrated Care for Older People (ICOPE) test at inclusion measure: Evolution of IADL score according to the results of the ICOPE test at inclusion measure: Cognitive assessment measure: Cognitive assessment measure: Cognitive assessment measure: Cognitive assessment measure: Cognitive assessment measure: Cognitive assessment sex: ALL minimumAge: 75 Years stdAges: OLDER_ADULT facility: Nantes University Hospital status: RECRUITING city: Nantes state: Loire Atlantique zip: 44093 country: France name: Jean-Baptiste GOURRAUD, MD role: CONTACT phone: 0240165143 email: JeanBaptiste.GOURRAUD@chu-nantes.fr lat: 47.21725 lon: -1.55336 hasResults: False
nctId: NCT06322004 id: 1718/2022 briefTitle: Video-Interpreting in Prehospital Emergency Medicine - Feasibility Study overallStatus: RECRUITING date: 2023-02-06 date: 2025-02-05 date: 2025-11-01 date: 2024-03-20 date: 2024-03-20 name: Medical University of Vienna class: OTHER briefSummary: 50 responsive patients with language barriers will be included in this study. The prehospital emergency physician will start video-interpreting via a tablet. Feasibility, quality of communication, usability as well as changes in diagnosis and treatment will be gathered and analysed. conditions: Communication Barriers studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 50 type: ESTIMATED measure: Technical Feasibility measure: Usability of video-interpreting measure: Impact on emergency physician's decisions measure: Demographic parameters sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Medical University of Vienna status: RECRUITING city: Vienna zip: 1090 country: Austria name: Christina Hafner, DDr. role: CONTACT email: christina.hafner@meduniwien.ac.at name: Maike Fink, Dr.med.univ. role: SUB_INVESTIGATOR name: Christina Hafner, DDr. role: PRINCIPAL_INVESTIGATOR lat: 48.20849 lon: 16.37208 hasResults: False
nctId: NCT06321991 id: S68382 briefTitle: Nodular Shrinking in Dupuytren Disease acronym: Echo overallStatus: RECRUITING date: 2024-02-15 date: 2026-03-01 date: 2026-03-01 date: 2024-03-20 date: 2024-03-22 name: Universitaire Ziekenhuizen KU Leuven class: OTHER briefSummary: Dupuytren disease (DD) is a common hand disorder with disabling finger contractures that may require surgery to restore function. In the early stages of the disease, the nodules (Tubiana stage 0) are usually painless, but a reason for concern to many patients. Not rarely, lifestyle measures and even risky treatment options as radiotherapy are advised, yet no therapy to prevent disease evolution has a solid proven effect. Furthermore, reliable non-invasive measurement of early stage DD is not validated.
Secure measurement of nodule evolution is a clinical challenge. To measure this evolution, ultrasound and MRI scanning are currently being performed. Stage 0 (nodules) is more challenging to quantify. A strict individual follow-up by the treating clinician is needed to standardize measurement of selected (treated) nodules. Therefore, simple ultrasound by the treating clinician may provide an good tool to collect data. This study aims to introduce and validate this non-invasive scan method and provide a prospective double blind investigation of a measurable effect of non-invasive preventive treatment for stage 0 DD to improve clinical outcome. conditions: Dupuytren's Disease studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Simple random allocation will be ensured by the principal investigators' designated staff (study nurse of IORT), who will not be involved in recruiting trial participants, medical care, drug administration or follow-up, through the generation of a random numbers table with computer software program. A randomization list will be prepared by the Sponsor's designated staff, not involved in recruiting Trial participants, medical care, drug administration or follow-up. primaryPurpose: TREATMENT masking: TRIPLE maskingDescription: To avoid bias, treatment arms will be blinded to Investigators, Trial staff, participants,.. as follows: vitamin E creme will be packaged and labelled in such a way that the visual appearance, nor the smell and/or touch of the creme can be distinguished from placebo (Vaseline). whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 80 type: ESTIMATED name: Vitamin E-creme (Remederm®) vs Vaseline (Placebo) name: Ultrasound measurement measure: Downsizing of the largest nodule diameter measure: VAS questionnaire on pain measure: VAS questionnaire on satisfaction measure: QUICK Dash for functionality measure: Abe Diathesis scoring measure: Range of motion measure: Recurrence rate sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: UZ Leuven status: RECRUITING city: Leuven state: Vlaams-Brabant zip: 3000 country: Belgium name: Ilse Degreef, Prof. Dr. role: CONTACT phone: +3216338843 email: ilse.degreef@uzleuven.be name: Anna Tarasiuk role: CONTACT phone: +3216338818 email: orthopedie.research@uzleuven.be lat: 50.87959 lon: 4.70093 hasResults: False
nctId: NCT06321978 id: MxBFlexUP ESP briefTitle: Mepilex Border Flex Utilization Pilot Spain acronym: MxBFlexUPESP overallStatus: RECRUITING date: 2024-02-16 date: 2024-05-31 date: 2024-05-31 date: 2024-03-20 date: 2024-03-20 name: Molnlycke Health Care AB class: INDUSTRY briefSummary: The aim of this study is to assess and describe the utilization of Mepilex® Border Flex and other foam dressings available in routine clinical practice in the management of patients with chronic wounds, in order to understand the pattern of use and the frequency of dressing changes in wound management. The study will also allow to gain information about the opinion of the HCPs and the patient's experience concerning wound management with foam dressings. This information may help to understand patient's health care optimization in terms of quality and efficiency. conditions: Wound studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: OTHER count: 40 type: ESTIMATED name: Mepilex Border Flex measure: Dressing use measure: Wound characteristics measure: Wound management measure: HCP opinion measure: Patient Experience measure: Costs sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: CS Ciudad Expo - Mairena de Aljarafe status: RECRUITING city: Sevilla state: Andalusia zip: 41927 country: Spain name: Andrés Roldán Valenzuela, Nurse role: CONTACT phone: +34609431073 email: andres.roldan.sspa@juntadeandalucia.es name: Andrés Roldán Valenzuela, Nurse role: PRINCIPAL_INVESTIGATOR lat: 37.38283 lon: -5.97317 hasResults: False
nctId: NCT06321965 id: 69HCL22_0599 briefTitle: Characterization of New Phenotypes of Patients With Spinal Muscular Atrophy Treated With SMN Restoring Therapy acronym: PHENO SMART overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2027-10-01 date: 2027-10-01 date: 2024-03-20 date: 2024-03-20 name: Hospices Civils de Lyon class: OTHER briefSummary: With the advent of new treatments for ASI, new phenotypes are emerging. The investigators propose to describe these new phenotypes by prospectively following children with ASI of all types treated with TRS and aged under 16 for 2 years.
nctId: NCT06321952 id: GTanareesuchoti briefTitle: Comparison of Accuracy and Functional Outcome Between Robotic and Gyroscopic Assisted Surgery in Primary TKA overallStatus: COMPLETED date: 2021-09-17 date: 2023-10-22 date: 2024-02-01 date: 2024-03-20 date: 2024-03-20 name: Mahidol University class: OTHER briefSummary: A randomized controlled trial was conducted with 72 participants who had moderate knee osteoarthritis (Kellgren and Lawrence grade 2-3). The patients were randomly assigned to either the robotic-assisted or gyroscopic-assisted group. Baseline characteristics, including age, body mass index, length of stay, and estimated blood loss, were recorded. The primary outcome measure was the accuracy of the hip knee angle, measured by scannogram film preoperatively and postoperatively at 3 months. Secondary outcomes included functional outcomes (KOOS, Oxford knee score, EQ-5D-5L, range of motion) assessed preoperatively and postoperatively at 3 months, as well as at 6 months postoperatively. conditions: Knee Arthropathy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized Controlled Trial primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 64 type: ACTUAL name: ROSA robotic assist TKA name: iassist TKA measure: accuracy of Robotic Assisted Surgery and Gyroscopic Based Instrument measure: Functional Outcome of Robotic Assisted Surgery and Gyroscopic Based Instrument measure: Functional Outcome of Robotic Assisted Surgery and Gyroscopic Based Instrument measure: Functional Outcome of Robotic Assisted Surgery and Gyroscopic Based Instrument measure: Functional Outcome of Robotic Assisted Surgery and Gyroscopic Based Instrument sex: ALL minimumAge: 55 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Siriraj Hospital city: Bangkok zip: 10700 country: Thailand lat: 13.75398 lon: 100.50144 hasResults: False
nctId: NCT06321939 id: NPCNS 001 briefTitle: Sequencing-based Counting of Plasma Epstein-Barr Virus DNA in Non-metastatic Nasopharyngeal Carcinoma overallStatus: RECRUITING date: 2024-01-11 date: 2026-12-31 date: 2028-12-31 date: 2024-03-20 date: 2024-03-20 name: Hunan Cancer Hospital class: OTHER briefSummary: The investigators aim to explore a new EBV DNA surveillance method with both high sensitivity and specificity in nasopharyngeal carcinoma (NPC) patients. the investigators aim to conduct plasma EBV DNA counting by next generation sequencing (NGS) in non-metastatic NPC patients on their diagnose, after two cycles of induction chemotherapy (IC), and 4-8 weeks after definitive radiotherapy. The investigators aim to explore whether sequencing-based counting is better than PCR analysis in plasma EBV-DNA surveillance, so as to monitoring tumor responses to treatment and for guiding individualized treatment adaptation in the future. conditions: Nasopharyngeal Carcinoma conditions: Herpesvirus 4, Human studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 50 type: ESTIMATED name: EBV-DNA next generation sequencing measure: Positivity rate of plasma EpsteineBarr virus (EBV) DNA by next generation sequencing measure: Overall survival measure: Distant metastasis failure-free survival measure: Locoregional failure-free survival measure: Failure-free survival measure: Patient reported quality-of-life score measure: Biomarker analysis sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hunan cancer Hospital status: RECRUITING city: Changsha state: Hunan country: China name: Yaqian Han role: CONTACT phone: +8618673176667 email: hanyaqiancs@163.com lat: 28.19874 lon: 112.97087 hasResults: False
nctId: NCT06321926 id: 154/2023 briefTitle: Evaluation of the "ActiveWaiting App" Encouraging Active Exercise-related Use of Waiting Time overallStatus: RECRUITING date: 2024-04-01 date: 2024-06-30 date: 2024-06-30 date: 2024-03-20 date: 2024-04-08 name: Ludwig Boltzmann Institute for Digital Health and Prevention class: OTHER briefSummary: The goal of this study (waitlist control study) is to evaluate the effectiveness of the ActiveWaiting App on increasing physical activity and improving quality of life in physically inactive adults in Austria.
2. Does the provision of the ActiveWaiting App lead to increased health-related quality of life, compared to a no-intervention control group? Participants will use the ActiveWaiting App over a period of seven days. During this period, they will answer daily questionnaires (3 - 6 questions) in order to gather their actual physical activity behaviour. Before and after the intervention period additional questionnaires on health-related quality of life will be sent to the participants.