hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06270654 id: 2023322-12280 briefTitle: Management of Perioperative Pain Using Erector Spinae Plane Block in Open Microscopic Lumbar Surgery overallStatus: RECRUITING date: 2023-06-01 date: 2024-05-01 date: 2024-06-01 date: 2024-02-21 date: 2024-02-21 name: University of Malaya class: OTHER briefSummary: The aim of this study is to compare patients receiving bilateral erector spinae block with ropivacaine vs control group in terms of pain score, total opioid consumption, hemodynamic changes intraoperatively, length of hospitalisation , time to ambulation post surgery and quality of recovery. conditions: Lumbar Spine Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: Erector spinae plane block name: Skin infiltration LA measure: Pain score at recovery, 30mins, 1, 2, 4, 8,12, 24 hours post-surgery measure: Total opioid consumption intraoperative measure: Total opioid consumption post-operative measure: Timing of first rescue dose of iv morphine measure: The quality of recovery score (QoR)-15 questionnaire at 24 hours post-operation measure: Hemodynamic changes intraoperative measure: Hemodynamic changes intraoperative measure: Length of hospital stays measure: Time to ambulation after surgery sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Universiti Malaya Medical Centre status: RECRUITING city: Kuala Lumpur state: Wilayah Persekutuan zip: 51100 country: Malaysia name: Wei Keang Tan, M.D. role: CONTACT phone: +60126655489 email: weikeang@ummc.edu.my name: Wei Keang Tan, MD. role: PRINCIPAL_INVESTIGATOR name: Tzi Sen Lee, MBBS role: SUB_INVESTIGATOR name: Dharmendra Ganesan, MBBS, FRCS role: SUB_INVESTIGATOR lat: 3.1412 lon: 101.68653 hasResults: False
nctId: NCT06270641 id: STUDY00018628 briefTitle: Increasing Physical Activity for Adults With Multiple Sclerosis (MS) overallStatus: RECRUITING date: 2024-02-16 date: 2025-04-30 date: 2026-09-30 date: 2024-02-21 date: 2024-02-22 name: University of Washington class: OTHER briefSummary: This study aims to advance the scientific understanding and potential future implementation of physical activity promotion by testing the efficacy of a phone-based app for increasing activity in insufficiently active patients with multiple sclerosis (MS). conditions: Multiple Sclerosis (MS) conditions: Fatigue conditions: Physical Inactivity studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 106 type: ESTIMATED name: ExerciseRx intervention measure: Physical activity: daily average step count measure: Activity volume measure: Minutes/week of moderate intensity aerobic activity measure: Fatigue - PROMIS Fatigue-MS Short Form 8a measure: Pain intensity - PROMIS Pain Intensity Short Form 3a measure: Depressive symptom severity - PROMIS Depression Short Form 8a measure: Sleep disturbance - PROMIS Sleep Disturbance Short Form 6a measure: Physical functioning - PROMIS Physical Function 10a measure: Pain interference - PROMIS Pain Interference Scale Short Form 6a measure: Social participation - PROMIS Satisfaction with Social Roles and Activities Short Form 8a measure: Social participation - PROMIS Ability to Participate in Social Roles and Activities Short Form 8a sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: UW Medicine status: RECRUITING city: Seattle state: Washington zip: 98133 country: United States name: Laurie Kavanagh, MPH role: CONTACT phone: 206-668-4168 email: lauriek@uw.edu lat: 47.60621 lon: -122.33207 hasResults: False
nctId: NCT06270628 id: NL85029.018.23 briefTitle: Personalized Live-remote Exercise Training for Cancer Survivors acronym: LION overallStatus: NOT_YET_RECRUITING date: 2024-02-20 date: 2026-10-31 date: 2027-10-31 date: 2024-02-21 date: 2024-02-21 name: UMC Utrecht class: OTHER name: German Cancer Research Center (DKFZ), Heidelberg, Germany name: German Sport University Cologne (DSHS), Cologne, Germany name: Cabrini Health (CAB), Malvern, Australia name: Karolinska Institute (KI), Stockholm, Sweden name: Netherlands Cancer Institute (NKI), Amsterdam, The Netherlands name: Heidelberg University Clinic and National Center for Tumor Diseases, Heidelberg, Germany name: Fundacion Onkologikao (ONK), San Sebastian, Spain name: Associação de Investigação e Cuidados de Suporte em Oncologia (AISCO), Nova de Gaia, Portugal briefSummary: Background
Many people with cancer face ongoing problems from their disease and treatments, like fatigue, reduced physical fitness, feeling anxious or down, and neuropathy. While exercise might help with these problems, most studies did not focus on tailoring exercise to address these specific complaints. Exercise programs under supervision (like with a trainer) seem to work better, but barriers for following such sessions are travel distance and time. Therefore, following an exercise program at home with a trainer guiding via video (live-remote) might be a good solution. But, it is unclear how effective this remote exercise program is for cancer patients.
This study investigates if personalized exercises done at home, with video guidance, can make cancer survivors feel better and manage their side effects more effectively. conditions: Neoplasms studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: RCT with two study arms: exercise group and wait list control group primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 350 type: ESTIMATED name: Exercise group measure: Health-Related Quality of Life measure: A standardized symptom score, per patient, based on the individual patient's main side-effect defined at baseline measure: A standardized symptom score, per patient, based on the individual patient's main side-effect defined at baseline measure: A standardized symptom score, per patient, based on the individual patient's main side-effect defined at baseline measure: A standardized symptom score, per patient, based on the individual patient's main side-effect defined at baseline measure: Health-related quality of life measure: Fatigue measure: Anxiety and Depression measure: CIPN_1 measure: CIPN_2 measure: Sleep measure: Pain measure: Cognitive problems measure: Work limitations measure: Body image measure: Fear of cancer recurrence measure: Habitual physical activity measure: Aerobic capacity on bike measure: Aerobic capacity on step measure: Handgrip strength measure: Upper body muscle strength measure: Lower body muscle strength measure: Sit to stand test measure: Physical function measure: Balance measure: Physical activity measure: Blood pressure measure: Resting heart rate measure: Weight measure: Height measure: Waist circumference measure: Hip circumference measure: Body composition measure: Inflammatory state measure: Growth factors measure: CRP measure: Hemoglobin measure: Leucocyte counts measure: Quality-adjusted life years measure: Health-care, patient and family costs measure: Productivity losses measure: Exercise-related (serious) adverse events measure: Participants experience of sensor-based guidance measure: Trainer experience of sensor-based guidance measure: Compliance sensor-based guidance measure: Technical feasibility of sensor-based guidance measure: Aerobic capacity measure: Upper body muscle strength measure: Lower body muscle strength measure: Core muscle strength measure: Physical functioning measure: Balance measure: Socio-demographics measure: Self-efficacy measure: Social Support measure: Medical history measure: Concomitant diseases measure: Cancer + concomitant medication measure: Cancer characteristics measure: Cancer treatment history sex: ALL minimumAge: 18 Years maximumAge: 100 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University Medical Center Utrecht city: Utrecht country: Netherlands lat: 52.09083 lon: 5.12222 hasResults: False
nctId: NCT06270589 id: IRB-2023-1684 briefTitle: Acute Effects of High-intensity Interval Training With Mindfulness-based Recovery on Executive Function in Children overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-05 date: 2026-05 date: 2024-02-21 date: 2024-02-21 name: Purdue University class: OTHER name: University of Oregon briefSummary: The goal of this randomized cross-over trial is to learn about the effect of a single bout of 20-min mindfulness-based high-intensity interval training (MF-HIIT), MF-only, and HIIT-only in relative to sitting rest on executive function (EF) in 10-12 years old children. The main question it aims to answer are:
Further, researcher will compare the cognitive outcome measures following the MF-HIIT compared with MF-only and HIIT-only conditions to see if combining MF with HIIT has greater beneficial effects on children's EF than MF and HIIT alone. conditions: Healthy Volunteers studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: BASIC_SCIENCE masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: MF-HIIT name: MF-only name: HIIT-only name: Sitting rest measure: Inhibition speed measure: Inhibition accuracy measure: Shifting speed measure: Shifting accuracy measure: N2-ERP measure: P3-ERP measure: State Mindfulness Scale for Physical Activity (SMSPA) measure: Rating of perceived exertion measure: Heart Rate measure: Dispositional mindfulness sex: ALL minimumAge: 10 Years maximumAge: 12 Years stdAges: CHILD hasResults: False
nctId: NCT06270576 id: HS3131 briefTitle: Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma acronym: Nasal-LPS overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2028-04 date: 2028-06 date: 2024-02-21 date: 2024-02-21 name: National Jewish Health class: OTHER briefSummary: A phase I clinical research study aimed at determining mechanisms that regulate airway mucosal inflammation in asthma endotypes using intranasal administration of endotoxin (lipopolysaccharide from E. coli) in healthy controls and subjects diagnosed with asthma. conditions: Asthma; Eosinophilic conditions: Asthma studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: NONE count: 60 type: ESTIMATED name: Lipopolysaccharides measure: Neutrophil heterogeneity using single cell RNA sequencing sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: National Jewish Health city: Denver state: Colorado zip: 80206 country: United States name: William J Janssen, MD role: CONTACT phone: 303-398-1366 name: Olivia M VerBurg, BA role: CONTACT phone: 303-398-1201 name: William J Janssen, MD role: PRINCIPAL_INVESTIGATOR lat: 39.73915 lon: -104.9847 hasResults: False
nctId: NCT06270563 id: P.T.REC/012/003967 briefTitle: High Intensity Laser Therapy Versus Scapular Stabilization Exercises on Ventilatory Function in Forward Head Posture overallStatus: COMPLETED date: 2022-10-01 date: 2023-12-01 date: 2023-12-01 date: 2024-02-21 date: 2024-02-21 name: Cairo University class: OTHER briefSummary: The purpose of the study is to compare between the efficacy of high intensity LASER therapy and scapular stabilization exercises on ventilatory functions in forward head posture patients conditions: Forward Head Posture studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 60 type: ACTUAL name: Postural advice name: Traditional exercise treatment name: Scapular stabilization exercises name: High intensity Laser therapy measure: Forced vital capacity (FVC) measure: Forced expiratory volume at one second (FEV1) measure: FEV1/FVC measure: Maximum voluntary ventilation (MVV) measure: Craniovertebral angle (CVA) measure: Neck Disability Index (NDI) measure: Upper thoracic chest expansion measure: Middle thoracic chest expansion measure: Lower thoracic chest expansion measure: Visual analogue scale (VAS) sex: ALL minimumAge: 30 Years maximumAge: 40 Years stdAges: ADULT facility: Cairo University city: Giza country: Egypt lat: 30.00808 lon: 31.21093 hasResults: False
nctId: NCT06270550 id: DMI in Spastic Diplegia briefTitle: Role of Dynamic Movement Intervention in Children With Spastic Diplegia overallStatus: RECRUITING date: 2024-03-01 date: 2024-11-01 date: 2024-12-01 date: 2024-02-21 date: 2024-02-21 name: Cairo University class: OTHER briefSummary: The study aims to investigate the effect of dynamic movement intervention approach on static and dynamic balance, quality of step length and cadence of walking pattern of children with spastic diplegic cerebral palsy. conditions: Spastic Diplegia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 40 type: ESTIMATED name: Dynamic Movement Intervention measure: Effect of Dynamic movement intervention on balance and quality of walking of the study group compared to control group, measured using Humac Balance System. sex: ALL minimumAge: 4 Years maximumAge: 7 Years stdAges: CHILD facility: Cairo University status: RECRUITING city: Cairo country: Egypt lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06270537 id: Dominus PMCF briefTitle: Post-market Clinical Trial of the Dominus® Stent-Graft acronym: DominusPMCF overallStatus: RECRUITING date: 2023-10-24 date: 2025-07-30 date: 2029-02-28 date: 2024-02-21 date: 2024-02-21 name: Braile Biomedica Ind. Com. e Repr. Ltda. class: INDUSTRY briefSummary: Real-world clinical trial evidence post-market, evaluating the safety and efficacy of the Dominus® StentGraft Endoprosthesis in treating thoracic aortic diseases, following the Instructions for Use conditions: Thoracic Aortic Dissection studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED name: Stent-Graft Dominus® Endoprosthesis measure: Early occurrence of adverse events (Safety Outcome) measure: Device Success measure: Absence of endoprosthesis fracture measure: Endoleak measure: Reintervention-free measure: Adverse Events sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hospital Evangélico de Vila Velha status: NOT_YET_RECRUITING city: Vila Velha state: Espirito Santo zip: 29118-060 country: Brazil name: Rodrigo Argenta role: CONTACT lat: -20.32972 lon: -40.2925 facility: Hospital Nossa Senhora da Conceição status: NOT_YET_RECRUITING city: Porto Alegre state: Rio Grande Do Sul zip: 91350-200 country: Brazil name: Eduardo A Silva role: CONTACT lat: -30.03306 lon: -51.23 facility: Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo status: RECRUITING city: Ribeirão Preto state: São Paulo zip: 14048-900 country: Brazil name: Ewaldo Joviliano role: CONTACT lat: -21.1775 lon: -47.81028 hasResults: False
nctId: NCT06270524 id: RCAPHM21_0433 briefTitle: Study of the C5a/C5aR1 Axis in IgG4-associated Disease: a Potential Therapeutic Target acronym: C5-MAG4 overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-05-01 date: 2026-12-31 date: 2024-02-21 date: 2024-02-21 name: Assistance Publique Hopitaux De Marseille class: OTHER briefSummary: This is a monocentric, comparative, cross-sectional, case-control study seeking to identify abnormalities of the C5a-C5aR1 axis between a population of patients with active IgG4-associated disease (MAG4) and two control groups: healthy subjects without MAG4 and patients with MAG4 in remission. conditions: Immunoglobulin G4-Related Disease studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: NONE count: 66 type: ESTIMATED name: Blood sampling measure: Serum C5a concentration measure: frequency of C5aR1+ monocytes among total monocytes measure: frequency of Tumor Growth Factor B+ (TGF-B+) monocytes among total monocytes sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06270511 id: 2222T1412 briefTitle: A Study to Investigate Different Formulations of S-337395 in Healthy Adult Participants overallStatus: RECRUITING date: 2024-03-13 date: 2024-05-31 date: 2024-06-19 date: 2024-02-21 date: 2024-03-19 name: Shionogi class: INDUSTRY briefSummary: The aim of this study is to investigate different formulations of S-337395. conditions: Healthy Volunteers studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: BASIC_SCIENCE masking: NONE maskingDescription: Part A will be open label; Part B will be double blind count: 50 type: ESTIMATED name: S-337395 name: Placebo measure: Part A: Plasma Concentration of S-337395 measure: Part B: Number of Participants Experiencing Treatment-emergent Adverse Events measure: Part A: Number of Participants Experiencing Treatment-emergent Adverse Events measure: Part A: Plasma Concentration of S-337395 (Venous Samples Versus Capillary Microsamples) measure: Part B: Plasma Concentration of S-337395 sex: ALL minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: ICON Lenexa status: RECRUITING city: Lenexa state: Kansas zip: 66219 country: United States lat: 38.95362 lon: -94.73357 hasResults: False
nctId: NCT06270498 id: 24811 briefTitle: Effect of Oral sucRosomIal Iron on exerciSE Capacity and Quality of Life in Patients With Heart Failure acronym: RISE-HF overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-06-01 date: 2024-02-21 date: 2024-02-21 name: Raffaele De Caterina class: OTHER name: University of Pisa, Italy briefSummary: The goal of this study is to investigate the effect of oral sucrosomial iron on exercise capacity and quality of life in patients with heart failure (HF) and iron deficiency (ID).
One group of participants will receive treatment with oral sucrosomial iron and the other group will receive treatment with placebo. conditions: Chronic Heart Failure conditions: Iron-deficiency conditions: Left Ventricular Systolic Dysfunction studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Sucrosomial iron name: Placebo measure: Exercise capacity measure: Quality of life measure: 6MWT distance improvement measure: Quality of life improvement measure: Exercise capacity (peak oxygen consumption) measure: F2-isoprostanes measure: Soluble NOX2-derived peptide (sNOX2-dp) measure: H2O2 measure: Phosphate measure: Fibroblast growth factor (FGF)-23 measure: N-terminal pro-B-type natriuretic peptide (NTproBNP) measure: Transferrin saturation (TSAT) measure: Ferritin measure: Serum iron measure: Soluble transferrin receptor (sTfR) measure: Hepcidin measure: Cardiac structure and function 1 measure: Cardiac structure and function 2 measure: Cardiac structure and function 3 measure: Cardiac structure and function 4 measure: Cardiac structure and function 5 measure: Cardiac structure and function 6 measure: Clinical outcome sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06270485 id: EA2/224/23 briefTitle: Influence of Positive-End-Expiratory-Pressure (PEEP) on Cardiac Output in Mechanically Ventilated Children acronym: IPCOM overallStatus: RECRUITING date: 2023-11-27 date: 2024-12 date: 2025-06 date: 2024-02-21 date: 2024-02-21 name: Charite University, Berlin, Germany class: OTHER name: University Medical Center Groningen briefSummary: Interventional Trial to determine the Effect of different PEEP levels on Cardiac output and right-ventricular function in mechanically ventilated children \< 5 years of age conditions: Ventilation Therapy; Complications conditions: Congenital Heart Disease conditions: Children, Only conditions: Hemodynamic Instability studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 56 type: ESTIMATED name: PEEP measure: Cardiac Output measure: TAPSE (cm) measure: respiratory mechanics measure: TAPSV (cm/s) measure: Global Strain RV (%/sec) measure: Lung Compliance (ml/Min/kg) measure: Esophageal Pressure (mbar) measure: EIT sex: ALL minimumAge: 1 Day maximumAge: 5 Years stdAges: CHILD facility: Deutsches Herzzentrum der Charité status: RECRUITING city: Berlin zip: 13353 country: Germany name: Jan Clausen, MD role: CONTACT phone: 004917620808764 email: jan-christoph.clausen@dhzc-charite.de name: Michael Emeis, MD role: SUB_INVESTIGATOR lat: 52.52437 lon: 13.41053 facility: UMCG status: RECRUITING city: Groningen country: Netherlands name: Martin Kneyber, PhD, MD role: CONTACT email: m.c.j.kneyber@umcg.nl name: Richard Hollander, MD role: CONTACT email: r.a.hollander@umcg.nl lat: 53.21917 lon: 6.56667 hasResults: False
nctId: NCT06270472 id: tipp technique briefTitle: Transinguinal Periperitoneal Technique in Inguinal Hernioplasty overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-04-01 date: 2024-02-21 date: 2024-02-21 name: Assiut University class: OTHER briefSummary: evaluation of feasibility and efficacy of trans inguinal periperitoneal technique by using conventional mesh inguinal hernia repair in general surgery department in Assiut university hospitals conditions: Hernia, Inguinal studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 20 type: ESTIMATED name: hernioplasty measure: Recurrence rate of inguinal hernia 2 years follow up . measure: Numerical rating score of pain sex: ALL minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT hasResults: False
nctId: NCT06270459 id: DSRB 2023/00954 briefTitle: Telerehabilitation Robotics for Upper Limb Rehabilitation After STroke acronym: TRUST overallStatus: NOT_YET_RECRUITING date: 2024-02-15 date: 2025-08-14 date: 2025-08-14 date: 2024-02-21 date: 2024-02-21 name: Tan Tock Seng Hospital class: OTHER name: National University Hospital, Singapore name: Singapore General Hospital briefSummary: There has been an observed decrease in motor and functional ability and non-use of the impaired limb in chronic patients. This is due to the immediate drop in intensive daily therapy (5 days per week for 3 hours/day) that is usually provided during the inpatient (acute) phase upon discharge from the hospital.
In this study, the investigators plan to address the low dosage of therapy in the post-acute discharge phase for stroke survivors. conditions: Stroke studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: The study is a multi-site prospective clinical trial, with single-arm study design with independent assessment of outcome measures (i.e., robotic metrics, standardized outcomes, quality of life, subjective measures). primaryPurpose: TREATMENT masking: NONE count: 54 type: ESTIMATED name: HMAN Robot measure: Compliance Rates measure: Fugl Meyer Motor Assessment (FMA) measure: Action Research Arm Test (ARAT) measure: Grip strength (KgF) measured by Digital Dynamometer (mean of 3 readings will be recorded) measure: System Usability Scale (SUS) measure: Intrinsic Motivation Inventory (IMI) sex: ALL minimumAge: 21 Years maximumAge: 90 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False