hackint0sh/New-Dataset huggingface dataset:
Three months after the study, a survey will be sent to the participants to check if the benefits have persisted. conditions: Stress, Psychological conditions: Burnout, Psychological conditions: Subjective Stress conditions: Occupational Stress studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: NONE count: 34 type: ESTIMATED name: Box Breathing name: Breathing and Mindfulness Exercise name: Everyday life control measure: Daily perceived stress measure: Daily expectation of perceived stress level on the following day measure: Level of agreement between expected and actually perceived level of stress measure: Compliance with the study protocol: number of participant reported outcomes measure: Compliance with the study protocol: number of performed anti-stress interventions measure: Successful study completion sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Charité - Universitätsmedizin Berlin status: RECRUITING city: Berlin zip: 10117 country: Germany name: Valentin M Vetter, MD role: CONTACT phone: 0049 30 450 566 298 email: valentin.vetter@charite.de lat: 52.52437 lon: 13.41053 hasResults: False
nctId: NCT06368778 id: 166591 briefTitle: Real-Time Biofeedback on Partial Weightbearing Training overallStatus: ACTIVE_NOT_RECRUITING date: 2023-04-13 date: 2025-04 date: 2025-04 date: 2024-04-16 date: 2024-04-26 name: University of Utah class: OTHER briefSummary: The purpose of this study is to investigate the effectiveness of a biofeedback device (Loadsol) in training healthy subjects to comply with partial weightbearing, and to compare its outcomes with the standard of care training. Partial weightbearing is an essential component of rehabilitation and recovery for many orthopedic patients, yet it remains challenging for individuals to accurately gauge their weightbearing restrictions without proper guidance and feedback.
By examining these objectives, this study aims to provide valuable insights into the potential benefits of using a biofeedback device in partial weightbearing training, and to establish whether its implementation can lead to improved outcomes in learning, compliance, and overall patient satisfaction. conditions: Physical Therapy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 105 type: ESTIMATED name: Verbal Advice name: Bathroom Scale name: Loadsol Biofeedback measure: Average peak force (Newtons, (N)) sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: University of Utah Orthopaedic Center city: Salt Lake City state: Utah zip: 84108 country: United States lat: 40.76078 lon: -111.89105 hasResults: False
nctId: NCT06368765 id: BL72 briefTitle: Oral Rehydration Solution and Dehydration Recovery overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-11 date: 2024-11 date: 2024-04-16 date: 2024-04-16 name: Abbott Nutrition class: INDUSTRY briefSummary: This is a prospective, randomized, controlled, blinded, crossover, study to evaluate the effects of an oral hydration solution. conditions: Dehydration studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: OTHER masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 20 type: ESTIMATED name: Oral Rehydration Solution (ORS) name: Water measure: Plasma Volume measure: Body Mass measure: Hydration Status Urine measure: Blood Biomarker - Plasma Osmolality measure: Blood Biomarker - Plasma Electrolyte Concentration measure: Blood Biomarker - Plasma Glucose Concentration measure: Body Temperature measure: Body Composition measure: Reaction Time measure: Handgrip Strength measure: Urine Volume measure: Hydration Status Saliva measure: Heart Rate measure: Blood Pressure measure: Thirst Sensation Scale measure: Gagge Thermal Scale measure: Urine Color measure: Palatability measure: Adverse Events sex: ALL minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT hasResults: False
nctId: NCT06368752 id: H-22063621 briefTitle: The Role of Endogenous GIP in Glycosis Metabolism During Fasting overallStatus: ENROLLING_BY_INVITATION date: 2023-05-04 date: 2023-12-12 date: 2025-12-31 date: 2024-04-16 date: 2024-04-16 name: Frederikke Koefoed-Hansen class: OTHER briefSummary: This research project aims to investigate the role of endogenous GIP during fasting. With the infusion of a GIP receptor antagonist (GIP\[3-30\]NH2), is it possible to selectively remove the effect of endogenous GIP, and thus describe its effects by comparing it with what happens during a saline infusion. conditions: Obesity studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: The trial is a randomized, double-blind, crossover study. We give intravenous infusion of GIP\[3-30\]NH2, and thus describe the effects of GIP by comparing with what happens during a saline infusion (placebo). primaryPurpose: BASIC_SCIENCE masking: DOUBLE maskingDescription: The infusion is mixed by an external coordinator. Neither the investigator or the participants knows whether is the GIP\[3-30\]NH2 infusion or saline infusion that is being given. Which infusion that is given on each trial day is randomized for each participant. whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 12 type: ESTIMATED name: GIP[3-30]NH2 name: Saline measure: Plasma glucagon concentrations measure: Plasma levels of C-peptide measure: Plasma levels of insulin measure: Resting metabolic rate measure: Activity in brown adipose tissue measure: Appetite measure: Blood pressure measure: Puls sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Gentofte Hospital city: Hellerup zip: 2900 country: Denmark lat: 55.73204 lon: 12.57093 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2024-04-10 uploadDate: 2024-04-11T04:12 filename: Prot_SAP_000.pdf size: 120286 hasResults: False
nctId: NCT06368739 id: STUDY00005622 briefTitle: Evaluation of Medicaid Food & Nutrition Support Program for Pregnant Women overallStatus: ACTIVE_NOT_RECRUITING date: 2022-10-17 date: 2024-05-01 date: 2024-08-01 date: 2024-04-16 date: 2024-04-16 name: University of Texas at Austin class: OTHER name: Driscoll Health Plan briefSummary: With funding from the Episcopal Health Foundation, the researchers will conduct a secondary data analysis to evaluate the impact of Driscoll Health Plan's Nurture program for pregnant members using claims data. conditions: Pregnancy Related conditions: Financial Gift conditions: Nutrition, Healthy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: From the eligible population, DHP randomly selected a subset of approximately 500 women during the pilot period, from which approximately 200 were in the program, the "exposed group." The women who were covered during the same period but were not selected were not exposed to the program and will compose the "comparison group." primaryPurpose: PREVENTION masking: NONE count: 224 type: ACTUAL name: Nurture program name: Regular benefits measure: Composite outcome 1: Adverse health events during pregnancy measure: Composite outcome 2: Adverse health events at birth and newborn-related measure: Emergency Department visits measure: Cost (outpatient) measure: Cost (inpatient) measure: Cost (pharmacy/medication) measure: Cost (total) measure: Delivery mode (vaginal, C-section) measure: Birthweight sex: FEMALE minimumAge: 30 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Driscoll Health Plan city: Corpus Christi state: Texas zip: 78415 country: United States lat: 27.80058 lon: -97.39638 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2024-01-24 uploadDate: 2024-02-12T16:26 filename: Prot_SAP_000.pdf size: 630078 hasResults: False
nctId: NCT06368726 id: SFND04042024 briefTitle: Result of tDCS in ASD Children With Comorbidities Like PANDAS, Rare Genetic Diseases or Autoimmune Disorders acronym: tDCS&ASD overallStatus: ENROLLING_BY_INVITATION date: 2024-04-01 date: 2025-05-01 date: 2025-07-01 date: 2024-04-16 date: 2024-04-16 name: Spanish Foundation for Neurometrics Development class: OTHER name: Fundacion para la Salud Materno Infantil briefSummary: Results of the application of 100 sessions of tDCS for 12 months in children between 6 and 11 years old with autism spectrum disorder with rare diseases, genetic problems or PANDAS conditions: Attention conditions: Visual Perceptual Weakness conditions: Social Behavior conditions: Fluency Disorder conditions: EEG With Periodic Abnormalities studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Two groups of childs: 90 childs receive tDCS treatment and 90 traditional treatments with Risperidone educational training, speech therapy and visual training. primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Assessments regarding clinical recovery will be conducted by an assessor blind to treatment allocation. whoMasked: INVESTIGATOR count: 180 type: ESTIMATED name: tDCS or Transcranial Direct Current Stimulation name: Risperidone measure: FFT measure: Power Density Spectrum Changes or PSD measure: ERP MMN changes measure: ERP MMN Changes measure: Attention measure: Social Skills measure: Language measure: Visual Contact sex: ALL minimumAge: 6 Years maximumAge: 11 Years stdAges: CHILD facility: New Remedies Ltd city: Liverpool state: Merseyside zip: L1 0AH country: United Kingdom lat: 53.41058 lon: -2.97794 hasResults: False
nctId: NCT06368713 id: PD-GIEX briefTitle: Exercise Improves Gastrointestinal Function in Peritoneal Dialysis Patients overallStatus: RECRUITING date: 2024-03-01 date: 2025-06-30 date: 2025-12-31 date: 2024-04-16 date: 2024-04-16 name: Sichuan Academy of Medical Sciences class: OTHER briefSummary: This study will investigate the impact of exercise on gastrointestinal function in peritoneal dialysis patients. conditions: Peritoneal Dialysis conditions: Exercise conditions: Gastrointestinal Function conditions: Quality of Life conditions: Chronic Kidney Diseases studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 132 type: ESTIMATED name: Exercise measure: Change in GIQLI measure: Change in GSRS measure: Change in PAC-SYM measure: Change in 6-MWT measure: Change in SGA measure: Change in measured Gastrointestinal Hormones sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital,School of Medicine, University of Electronic Science and Technology of China status: RECRUITING city: Chengdu state: Sichuan zip: 610000 country: China name: Jin Chen, Doctor role: CONTACT lat: 30.66667 lon: 104.06667 hasResults: False
nctId: NCT06368700 id: CL-00001 briefTitle: The Hyalex Early Feasibility Study (EFS) overallStatus: RECRUITING date: 2024-04-04 date: 2025-10 date: 2026-10 date: 2024-04-16 date: 2024-04-16 name: Hyalex Orthopaedics, Inc. class: INDUSTRY briefSummary: The Hyalex Early Feasibility Study is a prospective, multicenter, open-label, single-arm, 2-phase early feasibility study to evaluate the safety and technical performance of the HYALEX Knee Cartilage System for replacement of loss of articular cartilage and bone of the knee femoral condyles in symptomatic patients who require surgical treatment, will be enrolled in the study and undergo implantation of the HYALEX Knee Implant. conditions: Cartilage Injury conditions: Cartilage Damage studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DEVICE_FEASIBILITY masking: NONE count: 20 type: ESTIMATED name: Hyalex Knee Cartilage System measure: Freedom from implant rejection and infection. measure: Change in the Knee Injury & Osteoarthritis Outcome Score (KOOS) at 12 months. sex: ALL minimumAge: 21 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hospital for Special Surgery status: RECRUITING city: New York state: New York zip: 10021 country: United States name: Ava Neijna role: CONTACT phone: 917-260-3677 email: SGResearch@hss.edu name: Morgan Rizy role: CONTACT name: Sabrina Strickland, M.D. role: PRINCIPAL_INVESTIGATOR name: Andreas Gomoll, M.D. role: SUB_INVESTIGATOR lat: 40.71427 lon: -74.00597 facility: Oregon Health & Science University status: RECRUITING city: Portland state: Oregon zip: 97239 country: United States name: Jessica Ballin role: CONTACT phone: 503-418-9580 email: ballin@ohsu.edu name: Dennis Crawford, M.D. role: PRINCIPAL_INVESTIGATOR lat: 45.52345 lon: -122.67621 hasResults: False
nctId: NCT06368687 id: 2023-06112-01 briefTitle: TRANPAS - TReating Anorexia Nervosa Plus Autism Spectrum acronym: TRANPAS overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2026-12-31 date: 2026-12-31 date: 2024-04-16 date: 2024-04-16 name: Göteborg University class: OTHER briefSummary: In a pilot study, we will validate a so-called autism care location in an inpatient ward. The care location will be adapted for patients with anorexia nervosa (AN) and concurrent autism (AN+autism). In order to investigate the effect of a tailored care location for patients with AN + autism, the evaluation will include weight development and changes in nutritional intake, eating disorder and anxiety symptoms. The overall aim is to improve treatment for this specific AN subgroup, that otherwise has a worse prognosis regarding AN recovery. conditions: Anorexia Nervosa conditions: Autism Spectrum Disorder studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Pilot study. Ten consecutive patients with anorexia nervosa (AN) plus autism will be admitted to the autism care location at an inpatient ward for eating disorders. The planned period of care for each patient is 12 weeks. The patient will be assessed (including weight, height, self-report questionnaires and interviews) before admission, at discharge and 6 months later. primaryPurpose: TREATMENT masking: NONE count: 10 type: ESTIMATED name: Anorexia nervosa plus autism measure: BMI change between baseline and discharge 12 weeks later measure: Change of level of anxiety between baseline and discharge 12 weeks later measure: Change of Quality of life between baseline and discharge 12 weeks later sex: ALL minimumAge: 25 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06368674 id: 2023-00363 briefTitle: Bridging the Gap: Creating a Continuum of Care overallStatus: NOT_YET_RECRUITING date: 2024-05-02 date: 2026-12-31 date: 2027-02-01 date: 2024-04-16 date: 2024-04-22 name: Göteborg University class: OTHER name: Vastra Gotaland Region name: Narhalsan Reasearch and Development primary care Region Vastra Gotaland name: Sahlgrenska University Hospital, Sweden name: Forte briefSummary: Coordination and integration between care settings is essential for the quality of care of frail older patients. An active follow-up by a case manager (CM) after discharge form an acute geriatric hospital ward has the potential to bridge the gap between hospital, primary and municipality care for frail older people. This study evaluates the effects of an active follow-up by a CM in primary care after discharge from a geriatric ward, with the following research questions: Can an active follow-up by CM for frail older people discharged from an acute geriatric ward, compared to those not receiving active follow up, Maintain/increase independence in activities of daily living, self-rated health and life satisfaction? Increase satisfaction with health care? Reduce health care consumption/be cost-effective? How feasible is the intervention and the study design from the perspective of the caregivers and the older person? This is a clinical controlled study with a process evaluation. Inclusion criteria are 75 years or older, frail and admitted to a geriatric ward.
This study is relevant since today's highly specialized acute care is poorly adapted to the comprehensive needs of frail older people, and exposes them to avoidable risks such as loss of functional capacities causing unnecessary care needs and decreased wellbeing. Active follow-up by a CM after discharge may be an important way to integrate the care for frail older people, after receiving in-hospital geriatric care. This can improve the quality of care for this vulnerable group, and direct the right health care actions towards those in most need.
The intervention is a active follow-up after discharge by a CM (nurse) in primary care. CM will secure that discharge and care plans are executed and to address new needs. If there are unmet needs, the CM will ensure that adequate actions are performed to meet the needs. The intervention group consists of participants discharged to a primary health care centre with a CM, who actively follows-up after discharge. The control group consists of participants discharged to a primary health care centre without CM, and thereby no active follow-up after discharge. All participants will be followed-up by the research team during one year, concerning dependence in activities of daily living, self-rated health, health care consumption and satisfaction with care. conditions: Frailty conditions: Dependence conditions: Integrated Care studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Clinical control study primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 150 type: ESTIMATED name: Intervention group Case Manager (CM) name: Control Group measure: Dependency in Activities of Daily Living (ADL) measure: Self-rated health measure: Life satisfaction measure: Satisfaction with quality of care measure: Health economics sex: ALL minimumAge: 75 Years stdAges: OLDER_ADULT hasResults: False
nctId: NCT06368661 id: 23.79 Colo-MAR 1 briefTitle: Dietary Factors Associated to Colorectal Premalignant Lesions (COLOMAR-1) overallStatus: RECRUITING date: 2023-09-01 date: 2024-10-01 date: 2024-12-31 date: 2024-04-16 date: 2024-04-16 name: Fundación Vithas class: OTHER name: CEU San Pablo University briefSummary: This study aims to find a correlation between fish protein intake and other dietary habits and colorectal premalignant lesions in healthy volunteers. It also aims to describe gut microbial profiles for each dietary pattern, in order to elucidate the role of fish intake in cancer prevention. conditions: Nutrition Related Neoplasm/Cancer studyType: OBSERVATIONAL observationalModel: CASE_CROSSOVER timePerspective: CROSS_SECTIONAL count: 30 type: ESTIMATED measure: Dietary habits registry from participants: the dietary intake measure: Biomarkers in colon mucosa, precancerous lesions and colorectal cancer measure: Gut microbiota profile sex: ALL minimumAge: 45 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ciro Cabezas Checchi status: RECRUITING city: Vigo state: Pontevedra zip: 36206 country: Spain name: Ciro Cabezas Checchi, MD role: CONTACT phone: +34 986 82 11 00 email: CabezasCC@vithas.es lat: 42.23282 lon: -8.72264 hasResults: False
nctId: NCT06368648 id: CP-1 briefTitle: CoMind Early Feasibility Study acronym: CoMind EFS overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-03 date: 2025-04 date: 2024-04-16 date: 2024-04-16 name: CoMind Technologies Limited class: INDUSTRY name: Lindus Health briefSummary: The purpose of this research, which has been determined as non-significant risk by the central IRB overseeing the study, is to obtain information to help further develop a machine (a medical device) to measure the pressure around the brain from the outside (this pressure is called intracranial pressure or ICP). Monitoring and managing ICP is an important part of care for patients with conditions such as Traumatic Brain Injury (TBI). However, the current way of measuring ICP requires surgery to drill a hole into the skull, and therefore can introduce additional risks such as infections and pain.
Through collecting a large database of information from patients who have both the routine surgical device and the research device applied to their head, the research team will work to develop and test an effective and potentially safer way of monitoring patient ICP. conditions: Intracranial Pressure conditions: Intracranial Pressure Changes conditions: Traumatic Brain Injury conditions: Intracerebral Hemorrhage conditions: Encephalitis conditions: Encephalopathy conditions: Hydrocephalus conditions: Stroke conditions: Autoregulation studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 581 type: ESTIMATED measure: A test of the difference in estimation errors between two non-invasive ICP estimation models: one trained with ABP and CoMind One EFS CBFi, and one trained only using ABP measure: Models trained using CoMind CBFi and ABP will be evaluated based on their limits of agreement (LOA) with invasive ICP. measure: Demonstration that non-invasive ICP estimation using the CoMind One EFS device is insensitive to differences in skin tone across the population. measure: Demonstration of a non-invasive ICP model that can classify the transition between ICP 'states', i.e. transitions between low ICP (less than 20 mmHg), and high ICP (greater than 20 mmHg). measure: Demonstration of a non-invasive ICP waveform prediction model and assessment of its accuracy against the invasively-measured ICP waveform. measure: Demonstration of an non-invasive ICP model that can predict trends in ICP measure: A comparison of metrics of CAR derived from CoMind One EFS CBFi, CoMind One EFS device estimates of ICP, and ABP. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06368635 id: 2022-GSP-QN-8 briefTitle: The Cerebral Microcirculation Diseases and Coronary Microcirculation Disease Study acronym: CCMD overallStatus: RECRUITING date: 2024-01-01 date: 2024-12-31 date: 2025-03-31 date: 2024-04-16 date: 2024-04-18 name: Weijing Wang class: OTHER_GOV name: Chinese Academy of Medical Sciences, Fuwai Hospital briefSummary: Ischaemic heart disease (IHD) and degenerative brain disease are two major sources of death and disability affecting all countries. While the consequences of obstructive disease in major vessels supplying blood to both organs have been widely documented, less attention has been paid to disease processes affecting the microcirculation that may affect cardiac and cerebral function. Yet, over the last decade significant progress has been made in understanding the substrate of microvascular disease in both organs. In the heart, arteriolar thickening and capillary rarefaction that reduce the conductance of the microvasculature and its ability to vasodilate in response to increased myocardial oxygen demands constitute the leading cause of coronary microvascular dysfunction (CMD). In the brain, concentric hyaline thickening of deep penetrating small arteries (arteriolosclerosis) with associated fibrosis of the vessel wall constitutes the most frequent substrate for cerebral small vessel disease (CSVD). Of note, both CMD and CSVD share common risk factors, such as age, hypertension, and diabetes.3 These factors might have a common effect on the microvascular domain of cardiac and cerebral vascular beds.