hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06343272 id: LEGO briefTitle: Lymphocyte Enhancement in Gastroenteric Oncology overallStatus: RECRUITING date: 2022-03-22 date: 2024-12-22 date: 2025-02-28 date: 2024-04-02 date: 2024-04-03 name: Fondazione IRCCS Policlinico San Matteo di Pavia class: OTHER name: University of Pavia briefSummary: LEGO is single center double-blind randomized trial aimed at testing the efficacy of an essential ammino acid (EAA) supplementation in improving the absolute count of peripheral lymphocytes and the tolerance to chemotherapy in patients with advanced gastrointestinal malignancies not candidates to immune check-point inhibitors containing regimens. conditions: Advanced Gastrointestinal Cancers studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 54 type: ESTIMATED name: EAA supplementation name: Isocaloric placebo measure: Exit from lymphopenia measure: The change in the % of lymphocytes over time measure: The proportion of patients with G3-G5 toxicity measure: The percentage of chemotherapy dose administered compared to that expected for the patients. measure: plasma aminoacids composition chang during treatment sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS Policlinico San Matteo status: RECRUITING city: Pavia zip: 27100 country: Italy name: Alessandra Ferrari role: CONTACT phone: 0382.503689 phoneExt: +39 email: alessandra.ferrari@smatteo.pv.it name: Salvatore Corallo role: PRINCIPAL_INVESTIGATOR lat: 45.19205 lon: 9.15917 hasResults: False
nctId: NCT06343259 id: 2534 briefTitle: The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-08-01 date: 2024-08-14 date: 2024-04-02 date: 2024-04-02 name: Sisli Hamidiye Etfal Training and Research Hospital class: OTHER briefSummary: In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery. Cardiovascular events are a leading cause of mortality and morbidity following non-cardiac surgery, with myocardial injury after non-cardiac surgery (MINS) being a significant concern. MINS, characterized by asymptomatic elevation of troponin levels without accompanying ECG findings, is closely associated with postoperative mortality. With the increasing prevalence of comorbidities in the elderly population and the rising frequency of non-cardiac surgeries in this demographic, understanding the effects of different anesthesia types on postoperative myocardial injury is crucial. conditions: Myocardial Injury After Non-cardiac Surgery conditions: Hypotension During Surgery conditions: Anesthesia, General conditions: Anesthesia, Spinal studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 100 type: ESTIMATED name: General Anesthesia name: Spinal Anesthesia measure: Myocardial Injury After Non-Cardiac Surgery (MINS) measure: The duration of intensive care unit (ICU) stay measure: The duration of hospital stay sex: ALL minimumAge: 65 Years stdAges: OLDER_ADULT facility: Sisli Hamidiye Etfal Training and Research Hospital city: Istanbul zip: 34396 country: Turkey name: Mustafa Bilgehan AYIK role: CONTACT phone: +905377247984 email: drbilgehanayik@gmail.com lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06343246 id: MustafaKemalU briefTitle: Functional Inspiratory Muscle Training in Patients Diagnosed With Hypertension overallStatus: RECRUITING date: 2023-05-01 date: 2024-03-30 date: 2024-03-30 date: 2024-04-02 date: 2024-04-02 name: Mustafa Kemal University class: OTHER briefSummary: This study was planned to investigate the effectiveness of combined exercise training, that is, functional inspiratory muscle training, with breathing exercises to be applied with a portable, easy-to-use respiratory muscle strengthening device, on exercise capacity and peripheral muscle strength. conditions: Hypertension,Essential studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Prospective Randomized Controlled Study primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 45 type: ESTIMATED name: Inspiratory muscle training with device measure: Change of the exercise capacity from baseline to 8 week measure: Change of the peripheral muscle strenght from baseline to 8 week measure: change of the upper extremity exercise capacity from baseline to 8 week measure: change of the postural balance from baseline to 8 week measure: change of the physical activity from baseline to 8 week measure: change of the quality of life from baseline to 8 week measure: change of the Fev1/Fvc sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hatay Mustafa Kemal University status: RECRUITING city: Hatay state: Antakya country: Turkey name: İrem hüzmeli role: CONTACT email: fztirem@gmail.com lat: 38.40227 lon: 27.10486 hasResults: False
nctId: NCT06343233 id: FATE briefTitle: FAiling HearT in the Elderly (FATE) Study acronym: FATE overallStatus: RECRUITING date: 2019-11-19 date: 2024-12 date: 2024-12 date: 2024-04-02 date: 2024-04-02 name: IRCCS Multimedica class: OTHER briefSummary: In 2015 the Italian Ministry of Health invited the Cardiac Research Hospitals of Italy to constitute a Cardiac Network. The aim of the network is to facilitate and promote scientific and technological research in the setting of cardiovascular diseases and related risk factors. The Cardiology Network, responding to the indications of the National Health Research Program, which includes research models oriented towards prevention studies with objectives and priority areas of intervention such as "acquiring scientific knowledge necessary for implementing both secondary and tertiary prevention programs for patients and primary prevention for contacts, where indicated, or for subjects exposed to specific risk factors", aims to identify strategies and/or prognostic and predictive factors of outcomes through the construction of thoroughly studied case series and systematic collection of biological materials, as well as the definition of research models based on clinical outcomes.
The Study aims to examine the impact of clinical practice and therapies, analytically considering treatments and other important covariates that contribute in a complex manner to the therapeutic success of patients with heart failure. conditions: Heart Failure conditions: Frailty studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 5000 type: ESTIMATED name: usual care measure: Hospitalization or death at 12 months measure: Hospitalization or death at 6-12-18 months measure: hospitalizations and/or death from cardiovascular causes measure: association between events and patient characteristics sex: ALL minimumAge: 65 Years stdAges: OLDER_ADULT facility: Istituti clinici scientifici Maugeri - IRCCS Montescano ( Cardiologia DPT) status: RECRUITING city: Montescano state: Italy/Pavia zip: 27040 country: Italy name: Maria Teresa La Rovere, MD role: CONTACT phone: +39 0385 247290 email: mariateresa.larovere@icsmaugeri.it lat: 45.03196 lon: 9.28366 facility: IRCCS Centro Cardiologico Monzino status: RECRUITING city: Milan state: MIlano zip: 20138 country: Italy name: PierGiuseppe Agostoni, MD role: CONTACT phone: +39 02 58002772 email: piergiuseppe.agostoni@unimi.it lat: 45.46427 lon: 9.18951 facility: IRCCS Humanitas Research Hospital status: RECRUITING city: Rozzano state: Milano zip: 20089 country: Italy name: Cristina Panico, MD role: CONTACT phone: +39 0282241 email: cristina.panico@humanitas.it lat: 45.38193 lon: 9.1559 facility: IRCCS MultiMedica status: RECRUITING city: Sesto San Giovanni state: Milano zip: 20099 country: Italy name: Gaia Cattadori, MD role: CONTACT phone: +39 02 8687 8889 email: gaia.cattadori@multimedica.it lat: 45.53329 lon: 9.22585 facility: Ospedale Policlinico San Martino IRCCS status: RECRUITING city: Genova zip: 16132 country: Italy name: Pietro Ameri, MD role: CONTACT phone: +39 0103538928 email: pietroameri@unige.it lat: 44.40478 lon: 8.94438 facility: IRCCS Auxologico status: RECRUITING city: Milano zip: 20149 country: Italy name: Gianluca Caldara, MD role: CONTACT phone: +39 02 61911 251 email: g.caldara@auxologico.it lat: 45.46427 lon: 9.18951 facility: Fondazione IRCCS Ca'Granda - Ospedale Maggiore Policlinico status: NOT_YET_RECRUITING city: Milan zip: 20100 country: Italy name: Marco Vicenzi, MD role: CONTACT phone: +39 02 503 20512 email: marco.vicenzi@unimi.it lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06343220 id: AWARE 2.0 briefTitle: Project AWARE 2.0 to Improve Awareness, Willingness and Ability for Research and Enrollment in Clinical Research overallStatus: RECRUITING date: 2024-04-10 date: 2024-09 date: 2024-09 date: 2024-04-02 date: 2024-04-29 name: Huntington Study Group class: NETWORK name: Roche Products Limited briefSummary: The Project AWARE 2.0 Survey is intended to gain knowledge about the feelings, attitudes, and beliefs of HD family members, care partners and others affected by HD towards the way drug trials and observational studies are communicated and conducted. conditions: Huntington Disease studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 600 type: ESTIMATED measure: Examine awareness measure: Provide the HD research community with the insight. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Huntington Study Group status: RECRUITING city: Rochester state: New York zip: 14618 country: United States name: Elise Kayson, MS role: CONTACT phone: 800-487-7671 email: info@myhdstory.org lat: 43.15478 lon: -77.61556 hasResults: False
nctId: NCT06343207 id: 249637 briefTitle: Percussive Therapy Reduced EMG Activity During Calf Raise in Limbs With and Without Chronic Ankle Instability overallStatus: COMPLETED date: 2022-11-22 date: 2023-02-02 date: 2023-02-02 date: 2024-04-02 date: 2024-04-02 name: Charles University, Czech Republic class: OTHER briefSummary: To examine the acute effect of percussive therapy on peak calf muscle activation during standing heel raise in subjects with and without chronic ankle instability (CAI). conditions: Ankle Injuries studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A Randomized Controlled Trial primaryPurpose: BASIC_SCIENCE masking: SINGLE whoMasked: INVESTIGATOR count: 39 type: ACTUAL name: Percussive massage gun therapy measure: Percussive Therapy Reduced EMG Activity During Calf Raise in Limbs With and Without Chronic Ankle Instability. sex: ALL minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT facility: Faculty of physical education and sport, Charles University city: Praha zip: 16252 country: Czechia lat: 50.08804 lon: 14.42076 hasResults: False
nctId: NCT06343194 id: 6162 briefTitle: Changes in Electromyographic Activity in Aligner Treatment of Adult Patients With and Without Nocturnal Bruxism acronym: EMG_BRUX overallStatus: RECRUITING date: 2023-02-09 date: 2024-05-31 date: 2024-12-22 date: 2024-04-02 date: 2024-04-11 name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS class: OTHER briefSummary: The purpose of the study is to evaluate the effectiveness of clear aligners on the symptoms and signs reported by bruxism patients.
The results will allow the investigators to evaluate the progress of clear aligner therapy in bruxism patients and compare them with those of non-bruxism patients. conditions: Sleep Bruxism conditions: Masseter Muscle Hypertrophy conditions: Grinding Teeth studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: bruxism patients and non-bruxism patients primaryPurpose: TREATMENT masking: NONE count: 22 type: ESTIMATED name: Bruxoff ® measure: Change in potentials recorded by Bruxoff ® in bruxism patients. measure: Change of signs and symptoms of bruxism sex: ALL minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: UOC Odontoiatria Generale e Ortodonzia, Policlinico Agostino Gemelli Università Cattolica del Sacro Cuore status: RECRUITING city: Rome state: Lazio zip: 00168 country: Italy name: Massimo Cordaro, professor role: CONTACT phone: +39 0630154286 email: massimo.cordaro@unicatt.it lat: 41.89193 lon: 12.51133 hasResults: False
nctId: NCT06343181 id: IEO 1824 briefTitle: A Qualitative Study on Treatment Adherence in Patients With Metastatic Breast Cancer overallStatus: RECRUITING date: 2022-10-03 date: 2024-12-31 date: 2024-12-31 date: 2024-04-02 date: 2024-04-02 name: European Institute of Oncology class: OTHER briefSummary: Qualitative observational study with the aim to explore medication adherence in a sample of patients with metastatic breast cancer.
Patients with metastatic breast cancer receiving or having received oral oncologic therapy, and attending the Division of Medical Senology at the European Institute of Oncology, will be included and enrolled in this research project." conditions: Metastatic Breast Cancer studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 20 type: ESTIMATED measure: Evaluation of factors influencing patients' adherence to medical therapy sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: European Institute of Oncology status: RECRUITING city: Milan country: Italy name: Gabriella Pravettoni role: CONTACT lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06343168 id: frailty briefTitle: Prevalence of Frailty and Associated Factors in Coronary Artery Bypass Patients overallStatus: COMPLETED date: 2021-02-18 date: 2022-02-18 date: 2022-02-18 date: 2024-04-02 date: 2024-04-02 name: Uşak University class: OTHER briefSummary: This study aimed to determine the prevalence of and factors affecting frailty in patients with coronary artery bypass graft.
What are the prevalence of and factors affecting frailty in patients with coronary artery bypass graft Type of study: descriptive cross-sectional study Participant population: coronary artery bypass grafting patients conditions: Frailty studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 96 type: ACTUAL name: prevalence of frailty measure: Prevalence of frailty measure: Activities of Daily Living measure: Nutritional Assessment measure: Comorbidity measure: Cognitive Assessment sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Usak University city: Usak state: Center zip: 64200 country: Turkey lat: 38.67351 lon: 29.4058 hasResults: False
nctId: NCT06343155 id: E-10840098-202.3.02-235 briefTitle: Effect of Chronic Low Back Pain Treatment on Temporomandibular Disorder" overallStatus: NOT_YET_RECRUITING date: 2024-04-11 date: 2024-05-27 date: 2024-06-03 date: 2024-04-02 date: 2024-04-03 name: Medipol University class: OTHER briefSummary: According to the information obtained from clinical studies, it has been stated that Temporomandibular Disorder (TMD) is associated with chronic low back pain (LBP). In this study, participants will be divided into two groups. Only Rocabado's exercise will be given to the Rocabado's group (RG), and Rocabado's and therapeutic lumbar exercises will be given to the therapeutic group (TG). Warm-up exercises will be given before starting the exercises with the therapeutic group, and cool-down exercises will be given after the exercises with the therapeutic group. At the end of the sixth week, the effect of therapeutic lumbar exercises on TMD pain and function will be evaluated. conditions: Temporomandibular Disorder conditions: Chronic Low-back Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: There are two groups: Therapeutic group and Rocabado's group. primaryPurpose: TREATMENT masking: NONE count: 40 type: ESTIMATED name: Therapeutic Group name: Rocabado's Group measure: Temporomandibular Joint Range of Motion Measurement (ROM) measure: The Jaw Functional Limitation Scale 20 (JFLS-20) measure: Oral Health Impact Profile - 14 (OHIP-14) measure: The short-form McGill Pain Questionnaire (SF-MPQ) measure: Graded Chronic Pain Scale 2.0 total (GCPS 2.0) measure: Visual Analog Scale sex: ALL minimumAge: 23 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Istanbul Medipol University city: Istanbul country: Turkey name: İkra Çakıcı role: CONTACT phone: +90 05426696487 email: ikrabayraktar951@gmail.com lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06343142 id: 42038 briefTitle: Effects of Time of Day and Nut Intake on Cognitive Performance overallStatus: RECRUITING date: 2024-04-08 date: 2025-02-28 date: 2025-06-30 date: 2024-04-02 date: 2024-04-04 name: Monash University class: OTHER briefSummary: This is a 2 x 2-factor crossover design study to investigate the effects of time of day and nuts on post-meal cognitive performance. conditions: Cognitive Performance studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: 2 x 2-factor crossover design study primaryPurpose: PREVENTION masking: NONE count: 25 type: ESTIMATED name: Nuts name: Nut-free meal measure: N-back task - accuracy measure: N-back task - matched responses measure: N-back task - false alarm measure: N-back task - reaction time measure: Stroop test - congruent measure: Stroop test - incongruent measure: Stroop test - interference measure: Multitasking - pure blocks measure: Multitasking - mixed blocks measure: Multitasking - mixing cost measure: Satiety - hunger measure: Satiety - fullness measure: Satiety - satisfaction measure: Satiety - eating capacity measure: Satiety index sex: ALL minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: Department of Nutrition, Dietetics and Food - Monash University status: RECRUITING city: Notting Hill state: Victoria zip: 3168 country: Australia name: Barbara R Cardoso, PhD role: CONTACT phone: +61499840472 email: barbara.cardoso@monash.edu name: Maxine Bonham, PhD role: CONTACT phone: +61418 234 292 email: maxine.bonham@monash.edu lat: -37.905 lon: 145.1427 hasResults: False
nctId: NCT06343116 id: BPL-Nim-CRC-3001 briefTitle: Nimotuzumab Combined With Trifluridine/Tipiracil in the Treatment of Refractory Metastatic Colorectal Cancer acronym: NOTABLE-308 overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-04 date: 2027-04 date: 2024-04-02 date: 2024-04-02 name: Biotech Pharmaceutical Co., Ltd. class: OTHER briefSummary: This is a randomized, double-blind, placebo-controlled, multicenter study. The main purpose of the study is to evaluate the clinical efficacy and safety of nimotuzumab combined with trifluridine/tipiracil in third-line and beyond for the treatment of metastatic colorectal cancer (mCRC). This study planned to be divided into two parts: Part A and Part B. Part A (safety run-in) with a 3 + 3 study design, which primary endpoint is safety; Part B (main study) with a prospective, randomized, double-blind, placebo-controlled design, which primary endpoint is overall survival (OS). conditions: Refractory Metastatic Colorectal Cancer studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 420 type: ESTIMATED name: Nimotuzumab injection name: Placebo name: Trifluridine/tipiracil measure: overall survival (OS) measure: dose-limiting toxicity (DLT) measure: Progression free survival (PFS) measure: time to progress (TTP) measure: overall response rate (ORR) measure: disease control rate (DCR) measure: duration of response (DoR) measure: European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC-QLQ-C30) measure: European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Colorectal Cancer 29 (EORTC-QLQ-CR29) measure: Adverse Events measure: tumor-related markers sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06343103 id: IEO 1735 briefTitle: Study Evaluating Occupational Exposure to Antineoplastic Drugs acronym: BRIC overallStatus: RECRUITING date: 2022-08-02 date: 2025-12-31 date: 2025-12-31 date: 2024-04-02 date: 2024-04-02 name: European Institute of Oncology class: OTHER briefSummary: The multicenter study involves comparing two groups (an exposed group and a control group). The exposed group is selected from workers who perform their activities in drug handling areas (DH) or units for antineoplastic preparation (UFA), while the control group involves the voluntary participation of non-exposed workers (administrative staff).
The control group is selected based on the characteristics of the exposed group to ensure a homogeneous sample in terms of size and characteristics. conditions: Cytotoxicity studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 500 type: ESTIMATED name: Workers exposed name: Workers not exposed measure: Evaluation of the difference in micronuclei frequency sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS Ospedale Policlinico San Martino status: RECRUITING city: Genova country: Italy name: Sabrina Beltramini role: CONTACT lat: 44.40478 lon: 8.94438 facility: European Institute of Oncology status: RECRUITING city: Milan country: Italy name: Emanuela Omodeo Salè role: CONTACT lat: 45.46427 lon: 9.18951 facility: Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" status: RECRUITING city: Napoli country: Italy name: Piera Maiolino role: CONTACT lat: 40.85216 lon: 14.26811 facility: Istituto Oncologico Veneto Irccs status: RECRUITING city: Padova country: Italy name: Nicoletta Rigamonti role: CONTACT lat: 45.40797 lon: 11.88586 facility: Fondazione Policlinico Universitario Campus Bio-Medico status: RECRUITING city: Roma country: Italy name: Andrea Di Mattia role: CONTACT lat: 41.89193 lon: 12.51133 hasResults: False