nctId: NCT06309966 id: BHV7000-303 id: 2023-808811-21-00 type: REGISTRY domain: EU CTR briefTitle: Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy acronym: RISE 3 overallStatus: RECRUITING date: 2024-04 date: 2025-08 date: 2025-09 date: 2024-03-13 date: 2024-04-25 name: Biohaven Therapeutics Ltd. class: INDUSTRY briefSummary: The purpose of this study is to determine whether BHV-7000 is effective in the treatment of refractory focal epilepsy. conditions: Focal Epilepsy studyType: INTERVENTIONAL phases: PHASE2 phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 390 type: ESTIMATED name: BHV-7000 name: BHV-7000 name: Placebo measure: Change from Baseline in 28-day average seizure frequency during Weeks 8 to 16 of Treatment sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Dm Healthworks status: NOT_YET_RECRUITING city: Kissimmee state: Florida zip: 34741 country: United States name: Deeba Ahmad role: CONTACT phone: 407-716-1563 email: drdm22@gmail.com lat: 28.30468 lon: -81.41667 facility: Y&L Advance Health Care, Inc d/b/a Elite Clinical Research status: NOT_YET_RECRUITING city: Miami state: Florida zip: 33144 country: United States name: Yalexis Lorenzo role: CONTACT phone: 305-262-3396 email: ylorenzo@eliteclinicalresearch.com lat: 25.77427 lon: -80.19366 facility: Research Institute of Orlando status: NOT_YET_RECRUITING city: Orlando state: Florida zip: 32806 country: United States name: Michelle Clevenger role: CONTACT phone: 407-652-6011 email: Michelle@researchinstituteoforlando.com lat: 28.53834 lon: -81.37924 facility: Comprehensive Neurology Clinic status: NOT_YET_RECRUITING city: Orlando state: Florida zip: 32825 country: United States name: Elliuz Leal role: CONTACT phone: 407-208-0708 email: elealcrc@gmail.com lat: 28.53834 lon: -81.37924 facility: Knight Neurology status: RECRUITING city: Rockledge state: Florida zip: 32955 country: United States name: Joseph Hilde role: CONTACT phone: 855-564-4484 email: jhilde01@knightneurology.com lat: 28.35084 lon: -80.72533 facility: PENS status: RECRUITING city: Tampa state: Florida zip: 33609 country: United States name: Susan Ngo role: CONTACT phone: 813-873-7367 email: sngo@pensresearch.org lat: 27.94752 lon: -82.45843 facility: University Medical Center New Orleans status: NOT_YET_RECRUITING city: New Orleans state: Louisiana zip: 70112 country: United States name: Heather Scuderi role: CONTACT phone: 504-702-4624 email: heather.scuderi@lcmchealth.org lat: 29.95465 lon: -90.07507 facility: DelRicht Research status: NOT_YET_RECRUITING city: New Orleans state: Louisiana zip: 70119 country: United States name: Reggie Mister role: CONTACT phone: 504-336-2667 email: rmister@delricht.com lat: 29.95465 lon: -90.07507 facility: UNC-Chapel Hill status: NOT_YET_RECRUITING city: Chapel Hill state: North Carolina zip: 27514 country: United States name: Monica Coudurier role: CONTACT phone: 919-966-6727 email: m_coudurier@unc.edu lat: 35.9132 lon: -79.05584 facility: Cincinatti Children's Hospital status: NOT_YET_RECRUITING city: Cincinnati state: Ohio zip: 45229 country: United States name: Nikki Kamos role: CONTACT phone: 513-803-4552 email: nichole.kamos@cchmc.org lat: 39.12713 lon: -84.51435 facility: MUSC status: NOT_YET_RECRUITING city: Charleston state: South Carolina zip: 29425 country: United States name: Robin Bulgarino role: CONTACT phone: 843-792-1115 email: bulgarino@musc.edu lat: 32.77657 lon: -79.93092 facility: WR-ClinSearch status: NOT_YET_RECRUITING city: Chattanooga state: Tennessee zip: 37421 country: United States name: Jessica Benvenuto role: CONTACT phone: 423-698-4584 email: jbenvenuto@wakeresearch.com lat: 35.04563 lon: -85.30968 facility: ANESC Research status: NOT_YET_RECRUITING city: El Paso state: Texas zip: 79912 country: United States name: Shruti Konda role: CONTACT phone: 915-974-2200 phoneExt: 3 email: shrutik@anesc.net lat: 31.75872 lon: -106.48693 facility: UTHealth Houston status: NOT_YET_RECRUITING city: Houston state: Texas zip: 77030 country: United States name: Maria Poblete role: CONTACT phone: 713-500-7201 email: Maria.Poblete@uth.tmc.edu lat: 29.76328 lon: -95.36327 hasResults: False