hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06296576 id: CHM-2023/S49/06 briefTitle: Acceleration Time Assessment for Prediction of Critical Limb Ischemia acronym: ATACLI overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2026-05-01 date: 2026-05-01 date: 2024-03-06 date: 2024-03-06 name: Centre Hospitalier le Mans class: OTHER briefSummary: Critical Limb Ischaemia (CLI), the final stage of arterial disease, is a therapeutic emergency whose prognosis depends largely on the time taken to diagnose it. The growing prevalence of this condition and the associated healthcare costs make it an important public health objective. Diagnostic criteria for Critical Limb Ischaemia differ between learned societies and countries.
Its diagnosis is most frequently based on the combination of a clinical criterion (ischaemic decubitus pain and/or necrotic wounds, with a time to onset \> 2 weeks) and a haemodynamic criterion (ankle systolic pressure (ASP) \< 50mmHg or toe systolic pressure (TSP) \< 30 mmHg or transcutaneous oxygen pressure (TCPO2) \< 30 mmHg).
The main aim of our study is therefore to validate a reliable and accessible diagnostic tool for screening patients suffering from CLI so that they can be referred to a reference centre as early as possible. conditions: Critical Limb Ischemia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 431 type: ESTIMATED name: arterial ultrasound scan measure: Evaluate the intrinsic diagnostic performance of the maximum systolic rise time (TASmax) in the distal arteries of the foot sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Centre Hospitalier de CHOLET city: Cholet zip: 49300 country: France name: Marie GAUME role: CONTACT email: marie.gaume@ch-cholet.fr name: Jean-Eudes TRIHAN, MD role: PRINCIPAL_INVESTIGATOR lat: 47.06667 lon: -0.88333 facility: Centre Hospitalier du Mans city: Le Mans zip: 72000 country: France name: Christelle JADEAU role: CONTACT phone: 02 44 71 07 81 email: cjadeau@ch-lemans.fr name: Claire NEVEUX-BRECHETEAU, MD role: PRINCIPAL_INVESTIGATOR lat: 48.0 lon: 0.2 hasResults: False
nctId: NCT06296563 id: SHR1316-ICC-SD-001 briefTitle: Perioperative Treatment of Resectable Intrahepatic Cholangiocarcinoma With the Combination of Adebrelimab and Apatinib and HAIC overallStatus: RECRUITING date: 2024-03-01 date: 2027-03-01 date: 2029-03-01 date: 2024-03-06 date: 2024-04-17 name: Lei ZHAO class: OTHER briefSummary: The goal of this clinical trial is to explore the efficacy and safety of combined infusion chemotherapy with Adebrelimab and Apatinib in the perioperative treatment of resectable intrahepatic cholangiocarcinoma patients. The main question it aims to answer are:
Participants will receive receive neoadjuvant therapy with Adebrelimab combined with apatinib and FOLFOX-HAIC for 2 cycles (1 treatment cycle every 21 days, apatinib only used for the first cycle), and surgery was performed 14-28 days after the end of treatment. After 28 days of surgery, patients will continue to receive adjuvant treatment with Adebrelimab combined with apatinib for a maximum of one year. conditions: Intrahepatic Cholangiocarcinoma studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 20 type: ESTIMATED name: HAIC name: Adebrelimab name: Apatinib measure: Pathologic complete response (pCR) measure: Objective response rate (ORR) measure: Event free survival (EFS) measure: Overall Survival (OS) measure: Disease Control Rate (DCR) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Shandong Cancer Hospital and Institute status: RECRUITING city: Jinan state: Shandong zip: 250117 country: China name: Lei Zhao, MD role: CONTACT phone: +86 053167626368 email: drzhaolei@hotmail.com name: Peifei Sun, MD role: CONTACT phone: +86 053167626242 name: Lei Zhao, MD role: PRINCIPAL_INVESTIGATOR lat: 36.66833 lon: 116.99722 hasResults: False
nctId: NCT06296550 id: Dulce Digital CGM briefTitle: Enhancing Digitally Delivered Diabetes Education With Real-Time CGM overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-04-30 date: 2026-04-30 date: 2024-03-06 date: 2024-03-06 name: Scripps Whittier Diabetes Institute class: OTHER briefSummary: The current research study will add continuous glucose monitoring devices to the evidence-based text messaging diabetes education program for patients with type 2 diabetes for 6 months. Results on the effectiveness of this intervention will be compared for non-insulin using patients. conditions: Diabetes Type 2 studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 140 type: ESTIMATED name: Dulce Digital Text Messaging Intervention name: CGM Device measure: HbA1c measure: CGM Metric Time in Range measure: CGM Metric Time above Range measure: CGM Metric Time Below Range measure: Summary of Diabetes Self Care Activitiers (SDSCA) Survey measure: Diabetes Distress Scale sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Scripps Whittier Diabetes Institute city: San Diego state: California zip: 92121-1520 country: United States name: Athena Philis-Tsimikas, MD role: CONTACT phone: 858-729-4830 email: tsimikas.athena@scrippshealth.org name: Kallie Brown, MA role: CONTACT phone: 858-678-6294 email: brown.kallie@scrippshealth.org lat: 32.71533 lon: -117.15726 hasResults: False
nctId: NCT06296537 id: E-10840098-202.3.02-1434 briefTitle: Effectiveness of Balance Training And Dynamic Neuromuscular Stabilization Training in Amateur Athletes With Chronic Ankle Instability overallStatus: RECRUITING date: 2024-03 date: 2024-07 date: 2024-07 date: 2024-03-06 date: 2024-03-06 name: Medipol University class: OTHER briefSummary: The goal of this clinical trial is to determine and compare the effects of balance and dynamic neuromuscular stabilization training on ankle function ability, functional instability severity, physical activity level, muscle strength, proprioception, stabilization, balance, reaction time and performance of amateur athletes with chronic ankle instability. The main questions it aims to answer are:
Researchers will compare balance and dynamic neuromuscular stabilization training to see if effectiveness of ankle function ability, functional instability severity, physical activity level, muscle strength, proprioception, stabilization, balance, reaction time and performance. conditions: Ankle Inversion Sprain conditions: Chronic Instability of Joint conditions: Chronic Pain conditions: Athlete Foot studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: It is designed as a prospective, randomized, controlled study. primaryPurpose: TREATMENT masking: NONE count: 30 type: ESTIMATED name: Dynamic Neuromuscular Stabilization Training (DNS) name: Balance Training name: Conventional Training measure: Star Excursion Balance Test measure: Balance Error Scoring System (BESS) measure: Foot and Ankle Ability Measurement (FAAM) measure: Cumberland Ankle Instability Questionnaire measure: International Physical Activity Questionnaire - Short Form measure: Manual Muscle Strength Test with Hand Dynamometer measure: Single Heel Lift Test measure: Joint Position Sense Test measure: Foot Lift Test measure: Blazepod Reaction Time measure: Side Hop Test sex: ALL minimumAge: 18 Years maximumAge: 25 Years stdAges: ADULT facility: Sevval Yeşilkır status: RECRUITING city: Istanbul state: Beşiktaş zip: 34347 country: Turkey name: Sevval Yeşilkır role: CONTACT phone: +90 530 869 64 76 email: sevvalyslkr98@gmail.com name: Gizem Ergezen role: CONTACT phone: +90 216 681 24 70 email: gergezen@medipol.edu.tr lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06296524 id: SPC-2022-09 briefTitle: Effect of Footcore Exercises on Navicular Drop and Plantar Pressure Distribution in Asymptomatic Individual With Flatfoot overallStatus: RECRUITING date: 2024-03-01 date: 2024-03-01 date: 2024-03-30 date: 2024-03-06 date: 2024-03-07 name: Maharishi Markendeswar University (Deemed to be University) class: OTHER briefSummary: Pes Planus is a medical condition in which arch of the foot is flattened, causing the entire sole of the foot to contact the floor. For those with flat feet, footcore exercises might be an effective non-invasive therapy. Footcore exercises aim to strengthen the intrinsic foot muscles that maintain the foot arch, enhance foot function and reduce the risk of injury in persons with flatfoot. conditions: Flatfoot studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 30 type: ESTIMATED name: Footcore exercises and conventional therapy name: conventional therapy measure: Navicular Drop Test measure: Harris Mat for Plantar Pressure Distribution sex: ALL minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT facility: MMIPR status: RECRUITING city: Ambala state: Haryana zip: 133207 country: India name: Mousumi Saha, MPT role: CONTACT phone: +919366787310 email: msaha0029@gmail.com name: subhasish chatterjee, Phd(NEURO) role: CONTACT phone: +918950037407 email: subhasishphysio@gmail.com name: subhasish chatterjee, Phd role: PRINCIPAL_INVESTIGATOR lat: 30.36099 lon: 76.79782 hasResults: False
nctId: NCT06296511 id: Loughborough University briefTitle: The Influence of Acute Moderate-intensity Continuous Exercise on Appetite Regulation overallStatus: COMPLETED date: 2023-06-23 date: 2023-11-07 date: 2023-11-07 date: 2024-03-06 date: 2024-03-06 name: Loughborough University class: OTHER briefSummary: A key area of obesity research has focused on the link between appetite, energy balance and weight control. Within this area, several appetite-related hormones and cellular cytokines have been identified as key signals influencing appetite and food intake. This includes the appetite-suppressing hormone oxyntomodulin (OXM) and a cellular stress-induced cytokine growth differentiation factor 15 (GDF-15).
The aims of this study are: (1) to investigate the effect of acute moderate-intensity continuous exercise on oxyntomodulin and GDF-15 concentrations; (2) to investigate whether exercise-induced changes in circulating OXM and GDF-15 concentrations are correlated with subjective appetite perceptions and subsequent energy intake. conditions: Obesity conditions: Overweight studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: BASIC_SCIENCE masking: NONE count: 20 type: ACTUAL name: Exercise measure: Oxyntomodulin measure: Growth Differentiation Factor 15 measure: Visual analogue score (VAS) for subjective appetite measure: Energy intake sex: ALL minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: Loughborough University city: Loughborough zip: LE11 3TU country: United Kingdom lat: 52.76667 lon: -1.2 hasResults: False
nctId: NCT06296498 id: 20230505HU briefTitle: Application of L-PRF in Periodontal Surgery overallStatus: RECRUITING date: 2023-08-19 date: 2025-12 date: 2026-03 date: 2024-03-06 date: 2024-03-06 name: The University of Texas Health Science Center at San Antonio class: OTHER briefSummary: The study will compare the clinical outcomes of the two procedures, open flap debridement (OFD) compared to open flap debridement with leukocyte and platelet-rich fibrin (L-PFR) as well as differences in patient postoperative pain perception. conditions: Periodontal Diseases studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The proposed study is a split-mouth design, randomized, prospective clinical trial in which we will use either OFD alone or OFD + L-PRF for periodontal surgery. Both procedures are standard of care primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Participants will be blinded to the intervention which they are randomized to. whoMasked: PARTICIPANT count: 32 type: ESTIMATED name: Leukocyte Platelet-rich fibrin name: Standard of care OFD measure: Probing depth measure: Postoperative Pain (PROM) sex: ALL minimumAge: 18 Years maximumAge: 89 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The University of Texas Health Science Center at San Antonio status: RECRUITING city: San Antonio state: Texas zip: 78229 country: United States name: Charles Powell, DDS, MS role: CONTACT phone: 210-567-3593 email: powellc2@uthscsa.edu lat: 29.42412 lon: -98.49363 hasResults: False
nctId: NCT06296485 id: IRB-1996616 id: R01DK134446 type: NIH link: https://reporter.nih.gov/quickSearch/R01DK134446 briefTitle: Safer Aging With Diabetes Monitoring acronym: SAGE overallStatus: NOT_YET_RECRUITING date: 2024-03-30 date: 2027-03-30 date: 2028-01-31 date: 2024-03-06 date: 2024-03-06 name: Kaiser Permanente class: OTHER name: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) briefSummary: Older adults with type 2 diabetes are at higher risk for severe hypoglycemia and its related complications (including hospitalization and death) when taking insulin. This study proposes to evaluate, in a randomized clinical trial, a strategy of safe insulin prescribing based on an educational program that leverages continuous glucose monitoring to support older adults at high risk for hypoglycemia. If the aims of this project are achieved, this novel care strategy could be widely applied to reduce severe hypoglycemia episodes in older, high-risk adults with type 2 diabetes. conditions: Diabetes Mellitus, Type 2 conditions: Hypoglycemia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: 3-arm pragmatic randomized clinical trial primaryPurpose: PREVENTION masking: SINGLE maskingDescription: Participant randomization status will be masked during data collection (baseline and follow-up surveys) by research assistants whoMasked: OUTCOMES_ASSESSOR count: 360 type: ESTIMATED name: SAGE Group Sessions name: SAGE Group Sessions + Diabetes Pharmacist name: Usual Care measure: Hypoglycemia aggregate outcome measure: Self-reported hypoglycemia measure: Hypoglycemia-related utilization measure: Diabetes Distress measure: Hypoglycemia Confidence measure: Hypoglycemia Distress measure: Technology Proficiency measure: Confidence in Adjusting Insulin measure: Insulin Adjustment measure: Caregiver Action sex: ALL minimumAge: 75 Years stdAges: OLDER_ADULT hasResults: False
nctId: NCT06296472 id: MDQ23 briefTitle: De Quervain's Disease in the Acute Phase:a Study Aimed at Evaluating the Effectiveness of Standard Physiotherapy Treatment (HANDGUIDE), Compared to Experimental Treatment After Performing Ultrasound-guided Infiltrative Therapy. overallStatus: RECRUITING date: 2024-02-27 date: 2025-02-01 date: 2025-12-30 date: 2024-03-06 date: 2024-03-06 name: Istituto Ortopedico Rizzoli class: OTHER briefSummary: The objective of the study is to compare pain reduction and disability reduction in two groups of patients diagnosed with de Quervain syndrome who will undergo ultrasound-guided infiltrative treatment with corticosteroid as per normal clinical practice:
* the experimental group will subsequently carry out a program of eccentric exercises. conditions: De Quervain Disease conditions: Hand Tenosynovitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: INVESTIGATOR count: 134 type: ESTIMATED name: Rehabilitation name: Standard measure: Numeric Pain Rating Scale measure: Numeric Pain Rating Scale measure: Numeric Pain Rating Scale measure: Numeric Pain Rating Scale measure: Disabilities of Arm, Shoulder and Hand measure: Disabilities of Arm, Shoulder and Hand measure: Disabilities of Arm, Shoulder and Hand measure: Disabilities of Arm, Shoulder and Hand measure: Patient-Rated Wrist Evaluation measure: Patient-Rated Wrist Evaluation measure: Patient-Rated Wrist Evaluation measure: Patient-Rated Wrist Evaluation sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Istituto Ortopedico Rizzoli status: RECRUITING city: Bologna zip: 40136 country: Italy name: Fabio Vita, MD role: CONTACT email: fabio..vita@ior.it lat: 44.49381 lon: 11.33875 hasResults: False
nctId: NCT06296459 id: 20220556HU briefTitle: Radiographic Changes in the Maxillary Sinus Following Closed Sinus Augmentation overallStatus: RECRUITING date: 2022-09-21 date: 2024-12 date: 2025-03 date: 2024-03-06 date: 2024-03-06 name: The University of Texas Health Science Center at San Antonio class: OTHER briefSummary: A closed sinus augmentation is performed for dental implant placement. conditions: Dental Implant studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A 2 arm study using two methods of imaging in a participant primaryPurpose: TREATMENT masking: NONE count: 22 type: ESTIMATED name: 3D R100 scanner name: Conventional Radiograph measure: Dimensional Change in augmentation at 8mm measure: Dimensional Change in augmentation at 10mm measure: Dimensional Change in augmentation at 12mm sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The University of Texas Health Science Center at San Antonio status: RECRUITING city: San Antonio state: Texas zip: 78229 country: United States name: Charles Powell, DDS, MS role: CONTACT phone: 210-567-3593 email: powellc2@uthscsa.edu lat: 29.42412 lon: -98.49363 hasResults: False
nctId: NCT06296446 id: disability fibromyalgia briefTitle: Disability of People With Fibromyalgia in Poland overallStatus: RECRUITING date: 2024-04-15 date: 2024-05-01 date: 2024-11-01 date: 2024-03-06 date: 2024-04-16 name: University of Rzeszow class: OTHER briefSummary: Fibromyalgia is a syndrome characterized by chronic, generalized pain in muscles and joints with the presence of characteristic, symmetrically occurring so-called "tender points" - areas of the body that are excessively sensitive to pressure. The condition is associated with a feeling of chronic fatigue, mood and sleep disturbances and a sensation of body stiffness. These complaints are bothersome and significantly impair patients' functioning in every aspect of their lives. There are few studies evaluating the functioning and disability of people with fibromyalgia. No such study has been conducted in Poland to date. Therefore, the purpose of this study is to evaluate the functioning and disability of fibromyalgia patients and the relationship of the level of disability with selected factors, such as pain intensity, emotional state, sleep quality, etc. conditions: Fibromyalgia conditions: Disabilities Multiple studyType: OBSERVATIONAL observationalModel: CASE_CROSSOVER timePerspective: CROSS_SECTIONAL count: 700 type: ESTIMATED measure: disability measure: functioning measure: depression measure: Sociodemographic data sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Rzeszow status: RECRUITING city: Rzeszów state: Podkarpacie zip: 35-310 country: Poland name: Agnieszka Sozańska, professor role: CONTACT phone: +48 530172857 email: asozanska@ur.edu.pl lat: 50.04132 lon: 21.99901 hasResults: False
nctId: NCT06296433 id: HCB_2023_1196 briefTitle: Extended Reality-Assisted Therapy for Chronic Pain Management acronym: XR-PAIN overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-11-30 date: 2024-12-31 date: 2024-03-06 date: 2024-03-18 name: Institut d'Investigacions Biomèdiques August Pi i Sunyer class: OTHER briefSummary: The goal of this clinical trial is to test a home-based virtual reality rehabilitation application in patients with chronic low back pain. The main question it aims to answer are:
Is a prototype of a novel VR software application effective at reducing pain, improving daily function, improving range of motion, and reducing fear of movement in adult patients with chronic low back pain compared with a passive VR intervention? Participants in the treatment group will use the application daily for 20 minutes for a period of 3 weeks at home and unsupervised. Researchers will compare use of the VR application with a control group that watches 2D video to see if the treatment group have improved pain, disability, range of motion, and fear of movement. conditions: Chronic Pain conditions: Low Back Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 100 type: ESTIMATED name: VR rehabilitation name: VR video application measure: Brief Pain Inventory measure: Roland-Morris Disability Questionnaire measure: Short-Form 12 measure: Patient Global Impression of Change measure: Pain Catastrophization Scale measure: Spinal Range of motion measure: Adherence to treatment measure: Embodiment sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IDIBAPS city: Barcelona zip: 08036 country: Spain lat: 41.38879 lon: 2.15899 hasResults: False
nctId: NCT06296420 id: 24C304 briefTitle: Dysphagia After Thyroidectomy acronym: DYSPHATHYR overallStatus: RECRUITING date: 2024-01-31 date: 2025-11-30 date: 2026-11-30 date: 2024-03-06 date: 2024-03-12 name: Istituto Auxologico Italiano class: OTHER briefSummary: The goal of this observational study is to develop a questionnaire for measuring swallowing and throat discomfort symptoms in patients with goiter or thyroidectomy, which complies with the model of Rasch and which satisfies the fundamental measurement axioms (e.g., unidimensionality, linearity, generalizability). Developing a scale with such characteristics would provide clinicians and researchers with a reliable tool for assessing the impact of goiter and for measuring the outcomes after surgery.
In the following phases of the study, the questionnaire will be administered to patients before and after thyroidectomy. conditions: Goiter conditions: Thyroid Disease studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 420 type: ESTIMATED measure: The primary outcome measure will be the questionnaire which will be developed in the first phase of the study itself. measure: Patient and Observer Scar Assessment Scale (POSAS) 2.0. measure: Depression Anxiety Stress Scales-21 (DASS-21). sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS Istituto Auxologico Italiano status: RECRUITING city: Milan state: MI zip: 20122 country: Italy name: Stefano Scarano, MD role: CONTACT phone: +3902619116717 email: s.scarano@auxologico.it lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06296407 id: 01C319 briefTitle: Psychophysical Analysis of Adolescent Patients With Obesity and Efficacy of the Respiratory Approach (PSICOFISADOLOB). acronym: PSICOFISADOL overallStatus: RECRUITING date: 2023-08-08 date: 2024-12-31 date: 2024-12-31 date: 2024-03-06 date: 2024-03-06 name: Istituto Auxologico Italiano class: OTHER briefSummary: Specifically, the project aims to pursue the following objectives: