nctId: NCT06298097 id: 2019.11 briefTitle: Brain Connectivity Measured With High-density Electroencephalography acronym: NEUROCONN overallStatus: RECRUITING date: 2020-06-11 date: 2025-02-02 date: 2025-02-02 date: 2024-03-07 date: 2024-03-07 name: IRCCS San Camillo, Venezia, Italy class: OTHER briefSummary: Emerging scientific results show that disrupted functional connectivity in stroke can explain behavioral impairments and predict their recovery over time. However, no technique is yet available for widespread use in clinics to examine how neural synchronization in brain networks is altered in stroke patients. This is crucial to determine favorable prognostic factors and to define individualized rehabilitation protocols. Importantly, the investigators have successfully used high-density electroencephalography (hdEEG) in healthy individuals to measure neural synchronization in brain networks. In this project, the investigators will develop methods and tools based on hdEEG for assessing functional connectivity in stroke patients. These methods and tools will be employed to examine how neural changes occurring after brain lesions explain behavioral impairments. The project will open the way for the use of hdEEG at the patient's bedside, as a neurodiagnostic tool for stroke as well as other brain disorders. conditions: Stroke studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: NONE count: 170 type: ESTIMATED name: Connectivity measures measure: High-density electroencephalography measurements (work package 1, 2, and 3) measure: High-density electroencephalography measurements (work package 1, 2, and 3) measure: High-density electroencephalography measurements (work package 1, 2, and 3) measure: High-density electroencephalography measurements (work package 1, 2, and 3) measure: High-density electroencephalography measurements (work package 1, 2, and 3) measure: Magnetic Resonance Imaging measurement (work package 1, 2, and 3) measure: Magnetic Resonance Imaging measurement (work package 1, 2, and 3) measure: Magnetic Resonance Imaging measurement (work package 1, 2, and 3) measure: Magnetic Resonance Imaging measurement (work package 1, 2, and 3) measure: Magnetic Resonance Imaging measurement (work package 1, 2, and 3) measure: Muscle strength measurement (work package 3) measure: Muscle strength measurement (work package 3) measure: Muscle strength measurement (work package 3) measure: Muscle strength measurement (work package 3) measure: Muscle strength measurement (work package 3) measure: Sensorimotor impairment measurement (work package 3) measure: Sensorimotor impairment measurement (work package 3) measure: Sensorimotor impairment measurement (work package 3) measure: Sensorimotor impairment measurement (work package 3) measure: Sensorimotor impairment measurement (work package 3) measure: Spasticity measurement (work package 3) measure: Spasticity measurement (work package 3) measure: Spasticity measurement (work package 3) measure: Spasticity measurement (work package 3) measure: Spasticity measurement (work package 3) measure: Funtional skills measurement (work package 3). measure: Funtional skills measurement (work package 3). measure: Funtional skills measurement (work package 3). measure: Funtional skills measurement (work package 3). measure: Funtional skills measurement (work package 3). measure: Activities of daily living measurement (work package 3) measure: Activities of daily living measurement (work package 3) measure: Activities of daily living measurement (work package 3) measure: Activities of daily living measurement (work package 3) measure: Activities of daily living measurement (work package 3) measure: Pain measurement (work package 3) measure: Pain measurement (work package 3) measure: Pain measurement (work package 3) measure: Pain measurement (work package 3) measure: Pain measurement (work package 3) measure: Cognitive performance measurements (work package 3) measure: Cognitive performance measurements (work package 3) measure: Cognitive performance measurements (work package 3) measure: Cognitive performance measurements (work package 3) measure: Cognitive performance measurements (work package 3) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS San Camillo Hospital status: RECRUITING city: Venice country: Italy role: CONTACT email: n.ricercaclinica@hsancamillo.it lat: 45.43713 lon: 12.33265 hasResults: False