hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06291532 id: VRRS01 briefTitle: Feasibility and Usability of a Virtual Reality System overallStatus: ENROLLING_BY_INVITATION date: 2023-04-01 date: 2025-09-30 date: 2025-09-30 date: 2024-03-04 date: 2024-03-04 name: IRCCS Centro Neurolesi "Bonino-Pulejo" class: OTHER briefSummary: Intellectual disability (ID) and autism spectrum disorder (ASD) are often co-occurring neurodevelopmental disorders that require composite intervention. However, standardized rehabilitation programs presented several limitations due to behavioral problems and poor engagement in proposed activity. The Virtual Reality Rehabilitation System (VRRS) is a medical device is recognized as one of the most advanced systems to rehabilitate patients with motor, cognitive, linguistic and behavioral disorders. The use of VRRS offers the opportunity to adapting task parameters according to the patient's performance and the virtual system increases engagement and avoids boredom and frustration. the patients underwent a two months experimental intervention integrated into the regular activity of a semi-residential center for autistic adolescents and young adults. conditions: Autism Spectrum Disorder conditions: Intellectual Disability studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 100 type: ESTIMATED name: Rehabilitation with VRRS measure: Usability questionnaire measure: Virtual Reality Rehabilitation System (VRRS) electromedical device parameters: screen attention time measure: Virtual Reality Rehabilitation System (VRRS) electromedical device parameters: the number of repetitions of the exercises. measure: Virtual Reality Rehabilitation System (VRRS) electromedical device parameters:global scores for exercise. sex: ALL minimumAge: 6 Years maximumAge: 40 Years stdAges: CHILD stdAges: ADULT facility: IRCCS Centro Neurolesi Bonino Pulejo city: Messina zip: 98124 country: Italy lat: 38.19394 lon: 15.55256 hasResults: False
nctId: NCT06291519 id: SHN50343434 briefTitle: The Effect of Multisensory Stimulus Method on Pain and Physiological Parameters in Infants overallStatus: COMPLETED date: 2023-01-01 date: 2023-12-30 date: 2023-12-30 date: 2024-03-04 date: 2024-03-04 name: Istanbul University - Cerrahpasa (IUC) class: OTHER briefSummary: This study aimed to investigate the impact of employing the multi-sensory stimulation technique by both the mother and the nurse on the pain and physiological responses of infants aged 2-6 months during vaccination. The significance of pain experienced during vaccination in children is emphasized, potentially leading to avoidance behaviors toward healthcare services. There is growing evidence supporting the efficacy of non-pharmacological interventions. Multi-sensory stimulation, which integrates various stimuli such as taste, touch, and speech, alleviates infant pain. However, there has been a lack of studies assessing the effectiveness of this approach during vaccination administered by different healthcare providers. Hence, this study sought to explore the effects of multi-sensory stimulation by both mother and nurse applied to pain and physiological parameters. It is anticipated that the findings of this study will contribute to both pain management strategies and healthcare practices. conditions: Multisensory Stimulation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized controlled experimental design primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 96 type: ACTUAL name: Multi-sensory Stimulation Method-Mother Applying the Method to the Baby name: Multi-sensory Stimulation Method-Nurse Applying the Method to the Baby name: Breastfeeding Applied Group measure: The Effect of Multiple Sensory Stimulus Method measure: Comparison of the group in which the mother applied multiple sensory stimuli and the group in which the nurse applied multiple sensory stimuli sex: ALL minimumAge: 2 Months maximumAge: 6 Months stdAges: CHILD facility: Istanbul University-Cerrahpasa city: Istanbul state: None Selected zip: 34381 country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06291506 id: 6270 briefTitle: SUbstrate Ablation in Persistent Atrial Fibrillation for Elimination of Recurrences (SUPAFER). acronym: SUPAFER overallStatus: RECRUITING date: 2023-05-01 date: 2026-05-01 date: 2026-05-01 date: 2024-03-04 date: 2024-03-04 name: Hospital Universitario La Paz class: OTHER briefSummary: Antecedents: electrical isolation of pulmonary veins is the standard treatment for patients with atrial fibrillation. However, its efficacy is lower in persistent and chronic forms of this arrhythmia compared to paroxysmal atrial fibrillation. Many complementary techniques have been proposed, that added to pulmonary veins isolation, may reduce the recurrence rate of atrial fibrillation. However, none of them has obtained consistent results. Linear ablation aims to parcellate and modify the left atrial substrate responsible for atrial fibrillation maintenance. Previous studies have offered contradictory results using linear ablation.
Methods: SUPAFER is a multicenter, 1:1 randomized clinical trial that compares the efficacy of pulmonary veins isolation alone vs pulmonary vein isolation plus an specific protocol of left atrial linear ablation. Contrary to previous studies, the specific SUPAFER linear ablation is systematic, homogeneous and target atrial areas that have not been systematically ablated in previous trials. The trial aims at demonstrating the superiority of the combined ablative approach during 1-year follow-up. Daily transtelephonic ECG samples a 30 days continuous ECG monitoring are used to maximize de detection of recurrences, even asymptomatic. conditions: Persistent and Long Lasting or Chronic Atrial Fibrillation conditions: Atrial Fibrillation Ablation conditions: Linear Left Atrial Ablation conditions: Daily Transtelephonic Electrocardiogram studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: 1:1 randomization primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 176 type: ESTIMATED name: Radiofrequency ablation of heart atrial tissue. measure: Recurrences of sustained >30 secons atrial arrhythmias measured by daily ECG samples (Kardia Alivecor) and 30 days continuous Holter. measure: Acute intraprocedure efficacy. measure: Complications. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: La Paz University Hospital - IdiPaz status: RECRUITING city: Madrid country: Spain name: José Luis Merino, MD role: CONTACT phone: +34 912071301 email: lapaz@arritmias.net name: Sergio Castrejón Castrejón role: SUB_INVESTIGATOR lat: 40.4165 lon: -3.70256 hasResults: False
nctId: NCT06291493 id: CS-2024-0002 briefTitle: Precision Study Measuring Potassium (K) in Capillary Specimens overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2024-10 date: 2024-12 date: 2024-03-04 date: 2024-03-22 name: Abbott Point of Care class: INDUSTRY briefSummary: Assessing precision of i-STAT K test using the IUO i-STAT CG8+ cartridge on the i-STAT 1 Analyzer. conditions: Precision of Potassium (K) Test in Capillary Whole Blood studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Capillary precision analysis will be performed for Potassium K. primaryPurpose: DIAGNOSTIC masking: NONE count: 150 type: ESTIMATED name: Fingerstick blood draw measure: Precision for Potassium (K) Test sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06291480 id: NL78853.058.22 / STRUM briefTitle: Music Therapy After Stroke (Subacute Phase) overallStatus: RECRUITING date: 2023-01-01 date: 2024-08 date: 2024-12 date: 2024-03-04 date: 2024-03-04 name: Universiteit Leiden class: OTHER name: Amstelring briefSummary: The goal of this longitudinal, single-subject study is to investigate the role of motivation in music therapy for stroke patients within the subacute phase, who experience upper limb and/or attention deficits. The main questions it aims to answer are:
Participants will receive up to 9 music therapy sessions within 3-5 weeks, with functional assessments before and after each period. Each participant serves as their own comparison: researchers will compare a period with standard care only (control phase) to a period with music therapy plus standard care (intervention phase), the order of which will be randomized in advance. conditions: Stroke (CVA) or TIA conditions: Stroke/Brain Attack studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 20 type: ESTIMATED name: Neurologic Music Therapy measure: Motivation: Brain Injury Rehabilitation Trust Motivation Questionnaire (BMQ-S) [self-reported] measure: Motor Function: Action Research Arm Test (ARAT) measure: Motor Function: Barthel Index (BI) measure: Cognition: Cancellation Wechsler Adult Intelligence Scale (WAIS-IV) measure: Cognition: Color-Word Interference Test, also known as Stroop test measure: Cognition: WAIS IV Digit Span Test - Forward and Backward measure: Cognition: Verbal Fluency Test measure: Cognition: Trail Making Test (TMT) measure: Motivation to engage in musical activities: Barcelona Music Reward Questionnaire (BMRQ) measure: Quality of Life: EuroQol-5 (EQ-5D-5L) measure: Mood: Depression Anxiety Stress Scale-21 (DASS-21) measure: Mood: Visual Analogue Mood Scale (VAMS) measure: Personality Traits: The Big Five Index-Extra Short Form (BFI-2-XS) measure: Optimism: Life Orientation Test- Revised (LOT-R) measure: Brief self-report of therapy expectations and satisfaction with treatment sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Leo Polak Rehabilitation centre status: RECRUITING city: Amsterdam state: Nederland zip: 1069BW country: Netherlands name: Theo Dimitriadis, MSc role: CONTACT email: tdimitriadis@amstelring.nl lat: 52.37403 lon: 4.88969 hasResults: False
nctId: NCT06291467 id: RECHMPL23_0121 briefTitle: Plasma Beta-endorphin Levels and Suicidal Behavior acronym: BEST overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-03 date: 2026-03 date: 2024-03-04 date: 2024-03-04 name: University Hospital, Montpellier class: OTHER name: Institut de Génomique Fonctionnelle (IGF) de Montpellier briefSummary: It is an interventional research, monocentric, which involves only minimal risks and constraints.
The main objective is to compare plasma β-endorphin levels in patients hospitalized following a recent SA (≤72 hours) and in patients hospitalized for an EDC without lifetime history of SA. conditions: Suicide conditions: Depression conditions: Beta Endorphin studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 104 type: ESTIMATED name: Blood samples name: questionnaires measure: Comparison of plasma β-endorphin levels between patients with recent suicide attempt (≤ 72 hours) vs. patients with current major depressive episode without any lifetime history of suicide attempt. measure: - The kinetics of β-endorphin levels between two measurement points (inclusion and D7+/-2 days) in patients with recent suicide attempt (≤ 72 hours) vs. patients with current major depressive episode without any history of suicide attempt. measure: The level of depression in the last week before inclusion assessed by a self-administered questionnaire (MADRS) measure: The level of depression in the last week before inclusion assessed by a self-administered questionnaire (QIDS-16) measure: To assess the association between β-endorphin levels and and Suicidal ideation and history of suicidal behavior in the last week before inclusion, measure: To assess the association between β-endorphin levels and Anhedonia measure: To assess the association between β-endorphin levels and Current psychological and physical pain as well as usual and maximum over the 15 days before inclusion measure: To assess the association between β-endorphin levels and Anxiety, sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University hospital city: Montpellier zip: 34295 country: France name: Jessica DALAUDIERE role: CONTACT email: jessica.dalaudiere@chu-montpellier.fr lat: 43.61092 lon: 3.87723 hasResults: False
nctId: NCT06291454 id: 741100 briefTitle: GCF Levels of Chemokines in Periodontitis overallStatus: COMPLETED date: 2023-01-01 date: 2023-12-01 date: 2023-12-01 date: 2024-03-04 date: 2024-03-08 name: T.C. ORDU ÜNİVERSİTESİ class: OTHER briefSummary: This study aimed to determine CCL19/MIP3beta(β) and CCL20/MIP3alpha(α) in the gingival crevicular fluid (GCF) of the patients with different periodontitis phenotypes.
A total of 72 individuals, 24 with Stage III Grade B periodontitis (Group 1), 24 with Stage III Grade C periodontitis (Group 2), and 24 periodontally healthy (control group) (Group 3), were included in the study. GCF and clinical periodontal parameters were obtained at baseline. MIP3β and MIP3α levels in GCF were determined by ELISA. conditions: Periodontal Diseases studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 72 type: ACTUAL name: Routine periodontal examination measure: CCL19/MIP3beta(β) levels measure: CCL20/MIP3alpha(α) levels measure: CCL19/MIP3beta(β) levels and clinical parameters measure: CCL20/MIP3alpha(α) levels and clinical parameters sex: ALL minimumAge: 22 Years maximumAge: 55 Years stdAges: ADULT facility: Ordu University, Faculty of Dentistry city: Ordu zip: 52100 country: Turkey lat: 40.97782 lon: 37.89047 hasResults: False
nctId: NCT06291441 id: WUIPS briefTitle: Women Urinary Incontinence Prevalence Study (WUIPS) overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-06 date: 2025-12 date: 2024-03-04 date: 2024-03-04 name: IRCCS San Raffaele class: OTHER name: Università Vita-Salute San Raffaele briefSummary: The goal of this multicenter prospective and prevalence observational study is to punctually investigate and describe prevalence, predictors, quality of life and costs of Urinary Incontinence (UI) among female patients, female caregivers and female personnel in four hospitals in Northern Italy: San Raffaele hospital in Milan, San Raffaele Turro hospital in Milan, Zingonia Policlinico San Marco (BG) and Policlinico San Pietro in Ponte San Pietro (BG). conditions: Female Urinary Incontinence studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 1842 type: ESTIMATED name: No intervention measure: Prevalence of middle-aged women with urinary incontinence measure: Predictors of urinary incontinence in middle-aged women measure: Quality of life of middle-aged women with urinary incontinence measure: Social impact of middle-aged women with urinary incontinence measure: Costs of urinary incontinence for middle-aged women sex: FEMALE minimumAge: 40 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Policlinico San Marco Zingonia city: Osio Sotto state: Bergamo zip: 24040 country: Italy name: Elisabetta Bagnato role: CONTACT email: elisabetta.bagnato@grupposandonato.it name: Giulia Villa role: CONTACT phone: 0291751779 email: villa.giulia@hsr.it lat: 45.61608 lon: 9.58905 facility: Policlinico San Pietro Ponte San Pietro city: Bergamo zip: 24036 country: Italy name: Elisabetta Bagnato role: CONTACT email: elisabetta.bagnato@grupposandonato.it name: Giulia Villa role: CONTACT phone: 0291751779 email: villa.giulia@hsr.it lat: 45.69601 lon: 9.66721 facility: San Raffaele Turro Hospital (MI) city: Milan zip: 20127 country: Italy lat: 45.46427 lon: 9.18951 facility: San Raffaele Hospital (MI) city: Milan zip: 20132 country: Italy name: Sara Trapani role: CONTACT phone: +39 3389879403 email: trapani.sara@hsr.it name: Giulia Villa role: CONTACT phone: 0291751779 email: villa.giulia@hsr.it name: Stefania Rinaldi role: SUB_INVESTIGATOR name: Caglioni Martina role: SUB_INVESTIGATOR lat: 45.46427 lon: 9.18951 typeAbbrev: Prot hasProtocol: True hasSap: False hasIcf: False label: Study Protocol date: 2023-08-23 uploadDate: 2024-02-15T07:26 filename: Prot_000.pdf size: 544090 hasResults: False
nctId: NCT06291428 id: F-CNIC-2024-007 briefTitle: Raman Spectroscopy Compared to Flow Cytometry overallStatus: NOT_YET_RECRUITING date: 2024-10-15 date: 2026-12-30 date: 2026-12-30 date: 2024-03-04 date: 2024-03-04 name: Hospital Regional de Alta Especialidad del Bajio class: OTHER name: Optics research center briefSummary: The detection of MRD is associated with an increased risk of relapse and adverse prognosis in all patient groups diagnosed with acute lymphoblastic leukemia (ALL). However, it has a sensitivity level that detects one leukemic cell in 10,000 normal cells, along with other disadvantages such as the need for a panel of fluorescent antibodies for MRD detection, and its measurement is not standardized in many centers. New determination techniques may be necessary for MRD evaluation. Raman spectroscopy is proposed as a potential technique for MRD measurement, which is based on the inelastic scattering of light that occurs when it interacts with matter, causing optical scattering, where a portion of the radiation changes its wavelength (by Raman effect).
An observational, cross-sectional, comparative, and diagnostic test study will be conducted on bone marrow aspirate samples from adult and pediatric ALL patients to evaluate the presence of MRD using Raman spectroscopy, comparing the results of this technique with those obtained using flow cytometry. As a diagnostic test study, sensitivity, specificity, positive predictive value, and negative predictive value will be evaluated. The study will be conducted on adult and pediatric patients diagnosed with acute lymphoblastic leukemia treated at the hemato-oncology department of the UMAE No. 1 National Medical Center Bajio and the UMAE Hospital Gynecology-Pediatrics No. 48.
Patients diagnosed with ALL for whom MRD determination is clinically necessary will be included in the study. Their results will be evaluated using the gold standard, flow cytometry, and compared with results obtained through Raman spectroscopy. conditions: Acute Lymphoblastic Leukemia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 50 type: ESTIMATED name: Raman spectroscopy measure: measurable residual disease sex: ALL minimumAge: 2 Years maximumAge: 70 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06291415 id: 2022-523-GLOB1 briefTitle: The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP) overallStatus: RECRUITING date: 2024-04-02 date: 2026-04 date: 2026-11 date: 2024-03-04 date: 2024-04-19 name: Hutchmed class: INDUSTRY briefSummary: This is an open-label, multicenter study to evaluate the safety, tolerability, and efficacy of HMPL-523 in adult subjects with ITP. conditions: Immune Thrombocytopenia conditions: Blood Platelet Disorder conditions: Hematologic Diseases conditions: Purpura, Thrombocytopenic conditions: Purpura conditions: Blood Coagulation Disorder conditions: Thrombotic Microangiopathies conditions: Hemorrhagic Disorders conditions: Autoimmune Diseases conditions: Immune System Diseases conditions: Hemorrhage conditions: Pathologic Processes conditions: Skin Manifestations conditions: Thrombocytopenia conditions: Purpura, Thrombocytopenic, Idiopathic conditions: Primary Immune Thrombocytopenia conditions: ITP - Immune Thrombocytopenia studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Part 1: Dose escalation stage - subjects will receive one of 3 dose levels of HMPL-523 to determine the recommended dose of HMPL-523 for the randomized dose optimization- stage (Part 2)
nctId: NCT06291402 id: RC 34-1-2024 briefTitle: Nasal Packing Duration and Development of Pharyngitis After Septorhinoplasty Surgery overallStatus: NOT_YET_RECRUITING date: 2024-03-10 date: 2024-06-15 date: 2024-06-15 date: 2024-03-04 date: 2024-03-04 name: Al-Azhar University class: OTHER name: Benha University briefSummary: Septoplasty or septal reconstruction is a corrective surgical procedure performed to straighten the nasal septum. It may be associated with numerous complications. To minimize these complications, both nasal cavities are frequently packed with different types of nasal packing. In our study we will try to find relationship between duration of nasal packing and postrhinoplasty sore throat and pharyngitis. conditions: Rhinitis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED measure: Sore throat measure: Dysphagia measure: Throat irritation sex: ALL minimumAge: 20 Years maximumAge: 40 Years stdAges: ADULT facility: Neveen Kohaf city: Tanta zip: 11865 country: Egypt name: Neveen Kohaf, Ph.D role: CONTACT phone: +201060383012 email: nevenabdo@azhar.edu.eg name: Haney Bauiomy, M.D role: PRINCIPAL_INVESTIGATOR name: Ahmed Abosakaya, M.D role: PRINCIPAL_INVESTIGATOR lat: 30.78847 lon: 31.00192 hasResults: False
nctId: NCT06291389 id: RC.2.8.2023 briefTitle: Intraoperative Peak Airway Pressure Changes on Postoperative Pulmonary Function After Muscle Plication overallStatus: NOT_YET_RECRUITING date: 2024-03-10 date: 2024-05-15 date: 2024-05-15 date: 2024-03-04 date: 2024-03-04 name: Al-Azhar University class: OTHER name: Benha University briefSummary: An abdominal panniculus excision procedure is known as an abdominoplasty (panniculectomy). Musculofascial plication is a crucial aspect of abdominoplasty, especially for patients with significant divarication of the recti muscles. This study aimed to evaluate the effect of intraoperative changes in peak airway pressure (PAP) after muscle plication on postoperative pulmonary function. conditions: Abdominal Compartment Syndrome studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 120 type: ESTIMATED measure: Intraoperative peak airway pressure (PAP) measure: Duration of oxygen therapy measure: Post operative Tidal Volume (Vt) (Measured by spirometer) measure: Post operative Respiratory Rate (RR) measure: Hospital stay. sex: ALL minimumAge: 20 Years maximumAge: 50 Years stdAges: ADULT facility: Neveen Kohaf city: Tanta zip: 11865 country: Egypt name: Haney Bauiomy role: PRINCIPAL_INVESTIGATOR name: Ahmed Abosakaya role: PRINCIPAL_INVESTIGATOR lat: 30.78847 lon: 31.00192 hasResults: False