hackint0sh/New-Dataset huggingface dataset:
PartoMa Ethiopia will be implemented at Haramaya General Hospital and Hiwot Fana Comprehensive Specialized University Hospital, which are both busy maternity units in Eastern Ethiopia. Both are government hospitals with an annual delivery number of around 5,000. conditions: Stillbirth conditions: Obstetric Complication conditions: Maternal Death conditions: Perinatal Death conditions: Perinatal Morbidity studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 500 type: ESTIMATED name: PartoMa intervention(Locally achievable intrapartum care guideline), in house LDHF trainings measure: stillbirth measure: Birth Asphyxia measure: Maternal death measure: Cesarean sections and vacuum extractions measure: Process indicators of quality of intrapartum care measure: Birth attendant's perception of their work condition in the labour and delivery rooms measure: The women's experience of care received during delivery. sex: FEMALE minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Haramaya Hospital status: RECRUITING city: Harar state: Oromia country: Ethiopia name: Roba Ararsa, MD role: CONTACT lat: 9.31387 lon: 42.11815 facility: Hiwot Fana University Hospital status: NOT_YET_RECRUITING city: Harar country: Ethiopia name: Redwan Ahmed, MD role: CONTACT lat: 9.31387 lon: 42.11815 hasResults: False
nctId: NCT06272994 id: 231724 briefTitle: Swab Testing to Optimize Pneumonia Treatment With Empiric Vancomycin acronym: STOP-Vanc overallStatus: ENROLLING_BY_INVITATION date: 2024-04-03 date: 2027-12-01 date: 2027-12-31 date: 2024-02-22 date: 2024-04-08 name: Vanderbilt University Medical Center class: OTHER briefSummary: This is a single center, pragmatic, randomized clinical trial (pRCT) examining whether reporting the results of a negative rapid PCR back to the provider via a pager alert results in decreased vancomycin utilization for critically ill adults with community-acquired pneumonia when compared with usual care. conditions: Community-acquired Pneumonia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: This study will be performed as a single center, pragmatic, randomized clinical trial. primaryPurpose: TREATMENT masking: NONE count: 212 type: ESTIMATED name: MRSA Nasal Swab PCR measure: Vancomycin-free hours alive measure: Time Alive off Vancomycin measure: 30-day all-cause mortality sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Vanderbilt University Medical Center city: Nashville state: Tennessee zip: 37232 country: United States lat: 36.16589 lon: -86.78444 hasResults: False
nctId: NCT06272981 id: BWI202308 briefTitle: A Study of the THERMOCOOL SMARTTOUCH Surround Flow (SF) Catheter With the TRUPULSE Generator for Treatment of Drug Refractory Symptomatic PAFOUS acronym: PulseSmart overallStatus: RECRUITING date: 2024-02-28 date: 2025-08-29 date: 2025-08-29 date: 2024-02-22 date: 2024-04-26 name: Biosense Webster, Inc. class: INDUSTRY briefSummary: The purpose of this study is to demonstrate safety and effectiveness of the Biosense Webster (BWI) ablation system (THERMOCOOL SMARTTOUCH surround flow \[STSF\] catheter and TRUPULSE generator) when used for isolation of the atrial pulmonary veins (PVs) in treatment of participants with paroxysmal atrial fibrillation (PAF), an irregular heart rate that causing abnormal blood flow. conditions: Atrial Fibrillation studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 135 type: ESTIMATED name: Pulsed Field (PF) /Radiofrequency (RF) Catheter ablation measure: Number of Participants with Primary Adverse Events (PAEs) measure: Rate of Freedom from Documented (Symptomatic and Asymptomatic) Atrial Arrhythmia (Atrial Fibrillation (AF), Atrial Tachycardia (AT) or Atrial Flutter (AFL) of Unknown Origin) within 91-365 Days Post Index Procedure measure: Change from Baseline in Atrial Fibrillation Effect on Quality of Life (AFEQT) Total Score sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Royal Prince Alfred Hospital status: NOT_YET_RECRUITING city: Camperdown zip: 2050 country: Australia lat: -33.88965 lon: 151.17642 facility: Canberra Heart Rhythm status: RECRUITING city: Garran zip: 2605 country: Australia lat: -35.34206 lon: 149.10846 facility: John Hunter Hospital status: WITHDRAWN city: New Lambton Heights zip: 2305 country: Australia lat: -32.92466 lon: 151.69364 facility: Westmead Hospital status: RECRUITING city: Westmead zip: 2145 country: Australia lat: -33.80383 lon: 150.98768 facility: Southlake Regional Health Centre status: NOT_YET_RECRUITING city: Newmarket state: Ontario zip: L3Y 2P9 country: Canada lat: 44.05011 lon: -79.46631 facility: University of Ottawa Heart Institute status: NOT_YET_RECRUITING city: Ottawa state: Ontario zip: K1Y 4W7 country: Canada lat: 45.41117 lon: -75.69812 facility: Montreal Heart Institute status: NOT_YET_RECRUITING city: Montreal state: Quebec zip: H1T 1C8 country: Canada lat: 45.50884 lon: -73.58781 facility: McGill University Health Centre status: NOT_YET_RECRUITING city: Montreal state: Quebec zip: H3G 1A4 country: Canada lat: 45.50884 lon: -73.58781 hasResults: False
nctId: NCT06272968 id: EA2/252/23 briefTitle: Predicting Cognition After DBS for Parkinson's Disease 2 overallStatus: NOT_YET_RECRUITING date: 2024-02-25 date: 2027-12-01 date: 2030-12-01 date: 2024-02-22 date: 2024-02-22 name: Charite University, Berlin, Germany class: OTHER briefSummary: The aim of the study is to improve estimation of cognitive outcome after STN-DBS in PD in order to avoid risk factors by optimizing peri- and intraoperative management personalize therapeutic strategies for optimal long-term benefit.
The investigators will test possible predictors (clinical, neuropsychological, neuroimaging, electrophysiological and molecular) for the risk of cognitive dysfunction after deep brain stimulation of the subthalamic nucleus (STN-DBS) in Parkinson's disease (PD) at a single center (Charité - Universitätsmedizin Berlin, Germany). Data collection takes place prior to as well as 3, 12 and 60 months after the STN-DBS operation. Participation is proposed to all PD patients that are planned to undergo STN-DBS after careful examination of eligibility for this treatment according to standard operation procedures. conditions: Cognitive Impairment studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30 type: ESTIMATED name: Neuropsychological Testing measure: Change in cognitive performance after STN-DBS measure: Incidence of postoperative neurocognitive disorder sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Charité - Universitätsmedizin Berlin city: Berlin zip: 13351 country: Germany lat: 52.52437 lon: 13.41053 hasResults: False
nctId: NCT06272955 id: H-54417 briefTitle: LONG TERM EFFECTS OF SPINAL CORD STIMULATION acronym: SCS for FOG OL overallStatus: ENROLLING_BY_INVITATION date: 2024-01-04 date: 2025-06-30 date: 2025-06-30 date: 2024-02-22 date: 2024-02-22 name: Nora Vanegas class: OTHER briefSummary: Parkinson Disease (PD) patients experience a variety of motor issues such as walking difficulties, loss of balance, and freezing while walking, which impacts their quality of life. Some symptoms, like freezing of gait (FOG), do not respond to medications typically used to treat PD. Current surgical procedures used to alleviate PD symptoms also do not always improve FOG. Since many traditional therapies have failed for the treatment of FOG, researchers have proposed the use of newer treatments. Recent research in animal models and clinical human data using Spinal Cord Stimulation (SCS) has produced promising results, specifically showing improvement in FOG with the use of SCS in patients with PD.
2. Allowing patients to choose between the two SCS programming paradigms based on their motor, nonmotor and quality of life measures in PD patients with freezing of gait. conditions: Parkinson Disease studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 10 type: ESTIMATED name: Spinal Cord Stimulator (SCS) measure: Safety and Tolerability measure: New Freezing of Gait Questionnaire (NFOG-Q) score measure: Gait and Falls Questionnaire (GFQ) measure: MDS-UPDRS score measure: Timed Up and Go test (TUG) measure: Timed 10-meter walk (T10MW) measure: Mini-Mental State Examination (MMSE) measure: Montreal Cognitive Assessment Scale (MoCA) measure: Beck Depression Inventory (BDI-2) measure: Beck Anxiety Inventory (BAI) measure: Parkinson's Disease Questionnaire - 39 (PDQ39) measure: Non-Motor Symptoms Scale (NMSS) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Baylor College of Medicine city: Houston state: Texas zip: 77005 country: United States lat: 29.76328 lon: -95.36327 hasResults: False
nctId: NCT06272942 id: 22722 briefTitle: An Observational Study to Identify New Health Problems Arising After an Intensive Care Unit Admission in People With Acute Respiratory Distress Syndrome in the United States acronym: SeeMe Tool overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-31 date: 2025-08-30 date: 2025-08-30 date: 2024-02-22 date: 2024-04-23 name: Bayer class: INDUSTRY briefSummary: This is an observational study in which data already collected from people with acute respiratory distress syndrome (ARDS) admitted to an intensive care unit (ICU) are studied.
Researchers will collect data from participants admitted to ICU for ARDS for a maximum of 1 year before and after their stay. conditions: Acute Respiratory Distress Syndrome (ARDS) conditions: Post Intensive Care Syndrome (PICS) studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 140000 type: ESTIMATED name: An ICU admission and a temporally related ARDS diagnosis measure: Morbidity measure: Post ICU Syndrome-related morbidity measure: Incident morbidity measure: Post ICU Syndrome-related incident morbidity measure: Difference in prevalence rates pre versus post index hospitalization measure: Average total healthcare costs based on healthcare billing data in the one year post index ICU admission measure: Exploratory, descriptive difference in ranking of PICS domain comorbidity ratios observed for ARDS (ICU admissions) versus pneumonia (non ICU admissions). sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Bayer city: Whippany state: New Jersey zip: 07981 country: United States lat: 40.82454 lon: -74.4171 hasResults: False
nctId: NCT06272929 id: behcet and vascular briefTitle: Serum Elafin and Vascular Affection in Behcet Disease overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-04-01 date: 2024-02-22 date: 2024-02-22 name: Assiut University class: OTHER briefSummary: To measure the level of serum elafin in patients with BD. To assess the relation between serum elafin levels and disease activity. To evaluate the vascular complications in BD and determine their relationship with disease activity.
To assess the correlation between serum elafin and vascular affection and their relation with disease activity. conditions: Behcet Disease and Vascular Affection studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: RETROSPECTIVE count: 90 type: ESTIMATED name: doppler ultrasound measure: Measuring the level of serum Elafin in patients with BD in comparison to healthy participants. sex: ALL minimumAge: 20 Years maximumAge: 45 Years stdAges: ADULT hasResults: False
nctId: NCT06272916 id: Effect drugs on headache inCS briefTitle: Comparison of the Effect of Aminophylline, Magnesium Sulphate and Placebo in Prevention of Post Dural Puncture Headache in Parturient Undergoing Caesarean Section. overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-04 date: 2025-06 date: 2024-02-22 date: 2024-02-22 name: Assiut University class: OTHER briefSummary: This study will be conducted to better comprehend the effect of aminophylline in comparison to magnesium sulphate on preventing and/or treating PDPH. conditions: Post-Dural Puncture Headache studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 630 type: ESTIMATED name: Aminophylline , magnesium sulphate and placebo measure: Effect of the study drugs on the incidence and severity of PDPH sex: FEMALE minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT hasResults: False
nctId: NCT06272903 id: MBRU IRB-2023-228 briefTitle: Effect of Benzocaine 20% Topical Anesthesia on Pain Levels When Placing Separators in Children Receiving Hall Technique Crowns overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-09 date: 2024-12 date: 2024-02-22 date: 2024-02-22 name: Mohammed Bin Rashid University of Medicine and Health Sciences class: OTHER briefSummary: The goal of this RCT is to investigate the immediate effect of benzocaine 20% topical anesthesia on initial pain and discomfort levels associated with the placement of elastomeric orthodontic separators in children who are receiving Hall Technique crowns on primary molars, among children who have attended the Pediatric Dentistry Department, Dubai Dental Hospital (DDH), Mohammed Bin Rashid University (MBRU) in Dubai, the United Arab Emirates (UAE). conditions: Effect of Benzocaine on Pain studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 32 type: ESTIMATED name: 20% benzocaine, topical anesthetic name: Children's Toothpaste measure: Immediate Pain Levels measure: Patient Satisfaction During Procedure sex: ALL minimumAge: 4 Years maximumAge: 10 Years stdAges: CHILD facility: Mohammed Bin Rashid University Of Medicine and Health Sciences city: Dubai country: United Arab Emirates name: Iyad Hussein role: CONTACT phone: 971564715509 email: iyad.hussein@mbru.ac.ae name: Simran Kaur Sura role: PRINCIPAL_INVESTIGATOR lat: 25.0657 lon: 55.17128 hasResults: False
nctId: NCT06272890 id: GiresunU briefTitle: THE EFFECT OF MOTIVATIONAL INTERVIEWING ON NURSING STUDENTS WITH SOCIAL ANXIETY overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2024-05-20 date: 2024-07-20 date: 2024-02-22 date: 2024-02-22 name: Gazi University class: OTHER briefSummary: Studies support the idea that people diagnosed with social anxiety disorder score significantly lower on self-acceptance than healthy controls, and that self-compassion is inversely related to anxiety. Motivational interviewing has been shown to improve treatment outcomes as well as predict higher self-compassion and reduced resistance among participants.It also has the ability to increase the effectiveness of motivational interviewing as an intervention with perpetrators of intimate partner violence, promoting readiness for change and progression through stages of change. In this context, this study aims to examine the effect of motivational interviewing on social anxiety level, dating violence and self-compassion in nursing students with social anxiety. conditions: Motivation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The research was planned as a randomized controlled experimental study in a two-center parallel group pretest-posttest design. primaryPurpose: OTHER masking: SINGLE maskingDescription: In order to prevent detection bias in the study, all measurements will be made using an online survey form. In order to prevent reporting bias, the data obtained from the research will be coded as A and B by an independent statistician, transferred to the SPSS program and analyzed. whoMasked: OUTCOMES_ASSESSOR count: 58 type: ESTIMATED name: motivational interviewing measure: Motivational interviewing has an effect on nursing students' social anxiety. measure: Motivational interviewing has an effect on nursing students' dating violence. measure: Motivational interviewing has an effect on nursing students' self-compassion. sex: ALL minimumAge: 18 Years maximumAge: 25 Years stdAges: ADULT hasResults: False
nctId: NCT06272877 id: 129944-54 briefTitle: Fluidotherapy in Patients With Distal Radius Fractures overallStatus: RECRUITING date: 2024-02-20 date: 2024-06-20 date: 2024-07-20 date: 2024-02-22 date: 2024-02-22 name: Ahi Evran University Education and Research Hospital class: OTHER briefSummary: Distal radius fractures are the most common fractures when looking at upper extremity fractures. The incidence of distal radius fractures is increasing day by day, and when looking at the databases of various countries, its annual prevalence reaches 70,000 in the UK and 640,000 in the USA. Most of these fractures are related to osteoporosis and require appropriate treatment. If not, it causes loss of work force, permanent disability, and limitation in daily activities.
Fluidotherapy has also proven to be effective in reducing hand edema in patients with carpal tunnel syndrome and stroke, examining its effect on nerve conduction velocities, and warming hypothermic patients. Compared to these treatment methods, fluid therapy reduces both joint capsule and muscle temperature by 9°C and 5.7°C, respectively. has been reported to increase. conditions: Distal Radius Fractures conditions: Edema Arm conditions: Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomised controlled primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: The Investigator and the outcomes assesor will be different persons. Statician will be different person. whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 50 type: ESTIMATED name: Fluidotherapy name: conventional rehabilitation program measure: Visual analog scale measure: Visual analog scale measure: Visual analog scale measure: Wrist joint range of motion measure: Wrist joint range of motion measure: Wrist joint range of motion measure: Circumference (mm) measure: Circumference (mm) measure: Circumference (mm) measure: Gross Grip Strength: measure: Gross Grip Strength: measure: Gross Grip Strength: measure: Patient-Rated Wrist Evaluation (PRWE) questionnaire measure: Patient-Rated Wrist Evaluation (PRWE) questionnaire measure: Patient-Rated Wrist Evaluation (PRWE) questionnaire sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Kirsehir Research and Training Hospital status: RECRUITING city: Kirsehir state: Kişrsehşr zip: 40100 country: Turkey name: Levent Horoz, Asst Prof role: CONTACT phone: :+90 386 280 39 00 email: dr.leventhoroz@gmail.com lat: 39.14583 lon: 34.16389 hasResults: False
nctId: NCT06272864 id: BEGIN study briefTitle: BostonGene and Exigent Genomic INsight Study acronym: BEGIN overallStatus: NOT_YET_RECRUITING date: 2024-03-08 date: 2026-01-08 date: 2028-01-08 date: 2024-02-22 date: 2024-02-22 name: BostonGene class: INDUSTRY name: Exigent briefSummary: The BEGIN Study by BostonGene and Exigent Genomic INsight evaluates the efficacy of comprehensive molecular testing in advanced cancer patients. Using the BostonGene Tumor Portrait test, the study aims to identify actionable findings, assess feasibility, and determine patient enrollment in clinical trials. Four cohorts of 100 patients each will be studied over two years, focusing on treatment decisions and patient outcomes. This study seeks to demonstrate the clinical utility of genomic testing in guiding therapy for advanced cancer patients in community settings. conditions: Breast Cancer conditions: Non-small Cell Lung Cancer conditions: Melanoma conditions: Sarcoma studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 400 type: ESTIMATED measure: Frequency of actionable findings measure: Test turn-around time measure: Frequency of patients who receive molecularly matched therapy measure: Frequency of patients who receive molecularly matched therapy sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Northwest Medical Specialities city: Puyallup state: Washington zip: 98373 country: United States name: Sibel Blau, MD role: CONTACT lat: 47.18538 lon: -122.2929 hasResults: False
nctId: NCT06272851 id: Choroidal thickness by OCT briefTitle: Measuring Choroidal Thickness Using Optical Coherence Tomography overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2029-03-30 date: 2029-05-15 date: 2024-02-22 date: 2024-02-22 name: Assiut University class: OTHER briefSummary: To compare the choroidal thickness in eyes of diabetic patients with eyes of age matched controls using optical coherence tomography. conditions: Choroid Disease conditions: Diabetes Mellitus studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 122 type: ESTIMATED name: optical coherence tomography measure: comparison between choroidal thickness sex: ALL minimumAge: 30 Years maximumAge: 95 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06272838 id: 2023-19/145 briefTitle: Biodex Balance System in Patients With Parkinson's Disease overallStatus: RECRUITING date: 2024-02-28 date: 2024-09-14 date: 2024-10-14 date: 2024-02-22 date: 2024-02-22 name: Kirsehir Ahi Evran Universitesi class: OTHER briefSummary: Conventional balance exercises are an effective rehabilitation method applied in routine rehabilitation programs for Parkinson's patients. With technological developments, balance exercises conditions: Parkinson Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomised controlled primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Investigator and Outcomes Assessor will be different persons whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Biodex balance system name: The conventional balance exercise program measure: Berg Balance Scale measure: Berg Balance Scale measure: Berg Balance Scale measure: Biodex dynamic balance score measure: Biodex dynamic balance score measure: Biodex dynamic balance score measure: The fall efficacy scale measure: The fall efficacy scale measure: The fall efficacy scale measure: Time up and go test measure: Time up and go test measure: Time up and go test measure: The 8-item version of the Parkinson's Disease Questionnaire (PDQ-8) measure: The 8-item version of the Parkinson's Disease Questionnaire (PDQ-8) measure: The 8-item version of the Parkinson's Disease Questionnaire (PDQ-8) measure: The Five Times Sit to Stand Test measure: The Five Times Sit to Stand Test measure: The Five Times Sit to Stand Test measure: Beck Depression Inventory measure: Beck Depression Inventory measure: Beck Depression Inventory sex: ALL minimumAge: 40 Years maximumAge: 90 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Kırşehir Ahi Evran University Faculty of Medicine status: RECRUITING city: Kırşehir state: City Center zip: 40100 country: Turkey name: Basak Cigdem Karacay, Asist Prof role: CONTACT phone: 0905445094803 email: basak.cigdemkaracay@ahievran.edu.tr name: Basak Cigdem Karacay, Asist Prof role: PRINCIPAL_INVESTIGATOR lat: 39.14583 lon: 34.16389 hasResults: False