hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06325306 id: 2023/392 id: B7072023000102 type: OTHER domain: Comité d'Ethique Hospitalo-Facultaire Universitaire de Liège briefTitle: Physical Literacy-Based Intervention for Chronic Disease Management overallStatus: RECRUITING date: 2024-03-04 date: 2024-10-30 date: 2024-10-30 date: 2024-03-22 date: 2024-03-22 name: University of Liege class: OTHER name: Centre Hospitalier Universitaire de Liege briefSummary: The goal of this quasi-experimental study is to evaluate the effectiveness of a physical literacy-based intervention for chronic disease management in adults with chronic diseases participating in adapted physical activity group sessions in Belgium. The main questions it aims to answer are:
Researchers will compare 3 groups: a control group, a traditional Adapted Physical Activity (APA) group, and a Physical Literacy Oriented APA (APA+PL) group to see if integrating physical literacy components results in improved physical literacy levels, better sustained engagement in physical activities, and enhanced health outcomes. conditions: Chronic Disease conditions: Chronic Disease Management conditions: Aging studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 195 type: ESTIMATED name: Traditional APA name: APA+PL measure: Global Physical Literacy Score measure: Physical Activity Behavior and Engagement measure: Motivation and Confidence in Physical Activity measure: Physical Competence measure: Knowledge and Understanding of Physical Activity measure: Environment interactions measure: Meaningful and Purposeful Activities sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Centre Sportif du Sart-Tilman status: RECRUITING city: Liège zip: 4000 country: Belgium name: Jean-Pierre Weerts, M.A. role: CONTACT phone: +32 4366 3818 email: jpweerts@uliege.be name: Cédric Lehance, M.A. role: CONTACT phone: +32 477490055 email: clehance@chuliege.be name: Jean-Pierre Weerts, M.A. role: PRINCIPAL_INVESTIGATOR lat: 50.63373 lon: 5.56749 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2024-02-02 uploadDate: 2024-03-08T06:13 filename: ICF_000.pdf size: 334181 hasResults: False
nctId: NCT06325293 id: 2023-01295 id: 207286 type: OTHER_GRANT domain: Swiss National Science Foundation briefTitle: A Trial of Placebo Versus Macrolide for Mycoplasma Pneumoniae Childhood Pneumonia: MYTHIC Study acronym: MYTHIC overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2028-06-30 date: 2028-06-30 date: 2024-03-22 date: 2024-03-22 name: Christoph Berger class: OTHER briefSummary: The goal of this clinical trial is to compare a placebo (a look-alike substance that contains no active drug) with a commonly used antibiotic in children with Mycoplasma pneumoniae (a specific bacterium) induced community-acquired pneumonia. The main question it aims to answer is:
nctId: NCT06325280 id: Pro00132542 briefTitle: Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-12-31 date: 2027-12-31 date: 2024-03-22 date: 2024-03-22 name: University of Alberta class: OTHER briefSummary: There are many barriers to heart-healthy lifestyles in pediatric patients with acquired and congenital heart disease. Investigators want to further understand how participants heart and skeletal muscles work together during exercise and evaluate the impact on cardiac function. To do this, the investigators will use magnetic resonance imaging (MRI) to scan the heart and skeletal muscles during exercises to assess blood flow, oxygenation and function. conditions: Pediatric ALL conditions: Congenital Heart Disease conditions: Heart Transplantation studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 20 type: ESTIMATED name: Exercise cardiac MRI Assessment name: Cardiopulmonary Exercise Test measure: MRI assessment of cardiac structure at rest measure: MRI assessment of cardiac function at rest measure: Maximal exercise MRI assessment of cardiac structure measure: Cardioplumonary Exercise Test sex: ALL minimumAge: 10 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: University of Alberta city: Edmonton state: Alberta zip: T6G 2B7 country: Canada name: Rae Foshaug role: CONTACT phone: 780-407-7499 email: rae.foshaug@albertahealthservices.ca name: Michael Khoury, MD role: CONTACT phone: 780-492-0103 email: khoury1@ualberta.ca name: Michael Khoury, MD role: PRINCIPAL_INVESTIGATOR lat: 53.55014 lon: -113.46871 hasResults: False
nctId: NCT06325267 id: PLC briefTitle: Clinical Characteristics of Primary Liver Cancer overallStatus: RECRUITING date: 2010-01-01 date: 2024-08-31 date: 2024-08-31 date: 2024-03-22 date: 2024-03-27 name: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School class: OTHER briefSummary: Primary liver cancer (PLC) is the sixth most common malignancy in the world and the third most common cause of malignancy death. In 2020, there were about 905,677 new cases of PLC worldwide, and 830,180 deaths. Despite the availability of a variety of treatments for PLC, the 5-year net survival rate is still only 5% to 30%. How to effectively reduce the disease burden of PLC is a major public health problem that needs to be solved worldwide. The clinical characteristics and prognosis of PLC caused by different pathogenic factors are different. Therefore, it is of great significance to fully identify the risk factors of PLC, be familiar with the clinical characteristics and prognosis of disease development, and understand the relevant monitoring and follow-up strategies for the prevention and treatment of PLC. conditions: Primary Liver Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 1000 type: ESTIMATED measure: Epidemiological characteristics of overall cohort by liver disease etiology measure: Clinical characteristics of overall cohort by liver disease etiology measure: Survival rates of overall cohort and different etiologies measure: Risk factors of prognosis in overall cohort and different etiologies sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Nanjing Drum Tower Hospital status: RECRUITING city: Nanjing state: Jiangsu zip: 210008 country: China name: Jie Li, M.D., Ph.D role: CONTACT phone: 15863787910 email: lijier@nju.edu.cn lat: 32.06167 lon: 118.77778 hasResults: False
nctId: NCT06325254 id: MAFLD briefTitle: Clinical Characteristics of Metabolic Associated Fatty Liver Disease overallStatus: RECRUITING date: 2010-01-01 date: 2024-08-31 date: 2024-08-31 date: 2024-03-22 date: 2024-03-26 name: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School class: OTHER briefSummary: Metabolic associated fatty liver disease (MAFLD), which can lead to liver fibrosis, cirrhosis, liver failure and even hepatocellular carcinoma, poses a significant burden on society. With the improvement of living standards and changes in dietary habits, MAFLD patients show a younger and increasing trend, but there is still no specific drug. The clinical features and prognosis of MAFLD may be different with different metabolic disorder phenotypes and treatment measures. Therefore, further systematic study of the clinical characteristics and prognosis of MAFLD patients will be of great significance for the formulation of corresponding clinical prevention and treatment strategies. conditions: Metabolic Associated Fatty Liver Disease conditions: Clinical Features studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 3000 type: ESTIMATED measure: Clinical characteristics and follow-up outcomes of MAFLD patients measure: Clinical characteristics and follow-up outcomes of MAFLD patients under different subgroups measure: Baseline clinical characteristics MAFLD patients measure: Risk factors for progression to cirrhosis and hepatocellular carcinoma sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Nanjing Drum Tower Hospital status: RECRUITING city: Nanjing state: Jiangsu zip: 210008 country: China name: Jie Li, M.D.,Ph.D role: CONTACT phone: 15863787910 email: lijier@nju.edu.cn lat: 32.06167 lon: 118.77778 hasResults: False
nctId: NCT06325241 id: 20200048-01H briefTitle: Validating the Use of Frailty Measurements to Predict Care & Quality of Life overallStatus: ACTIVE_NOT_RECRUITING date: 2022-12-12 date: 2025-03-31 date: 2025-03-31 date: 2024-03-22 date: 2024-04-24 name: Ottawa Hospital Research Institute class: OTHER briefSummary: The aim of this research program is to validate frailty measurements as a risk stratification tool to predict deteriorations in patient-reported outcomes, to gain a better understanding of patient preferences for care within varying degrees of frailty, and to assess differences in frailty measurement between patients and their clinicians.
This work will provide a foundation in the development of customized interventions for people with COPD and varying degrees of frailty, with the goal of improving quality of life and optimizing health system service delivery for patients and their care givers. conditions: Chronic Obstructive Pulmonary Disease studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 123 type: ACTUAL name: No intervention measure: Respiratory Health Related Quality of Life measure: Burden of symptoms - COPD Assessment measure: Burden of symptoms - Dyspnea measure: Psycho-social well being - Anxiety measure: Psycho-social well being - Depression sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Ottawa Hospital, General Campus city: Ottawa state: Ontario zip: K1J 0J2 country: Canada lat: 45.41117 lon: -75.69812 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2022-09-22 uploadDate: 2022-11-29T13:05 filename: Prot_SAP_000.pdf size: 617838 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form: Verbal consent date: 2022-11-09 uploadDate: 2022-11-29T13:08 filename: ICF_001.pdf size: 317754 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form: English Information Sheet date: 2022-11-09 uploadDate: 2022-11-29T13:11 filename: ICF_002.pdf size: 161773 hasResults: False
nctId: NCT06325228 id: NKBBN/241/2023 id: SONP/SP/549693/2022 type: OTHER_GRANT domain: Minister of Education and Science briefTitle: Musculoskeletal Injuries, Sports Performance, Sports Specialization, and Quality of Life in Young Athletes overallStatus: ACTIVE_NOT_RECRUITING date: 2023-02-01 date: 2025-05-01 date: 2025-09-01 date: 2024-03-22 date: 2024-04-24 name: Medical University of Gdansk class: OTHER name: Ministry of Science and Higher Education, Poland briefSummary: The primary aim of this observational cohort study is to assess sports specialization, sports performance, history of injuries (prevalence, types, areas, duration) and quality of life in young healthy athletes aged 8-16 from Poland. Athlete profiles will be created based on the variables (explained in detailed description) examined. Furthermore, the investigators will perform one-year injury follow-up.
* Does value of the specific muscle (lower limb) isometric strength will be associated with the dynamic balance scores in young healthy athletes? conditions: Sport Injury conditions: Healthy conditions: Injury;Sports conditions: Quality of Life studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 373 type: ACTUAL measure: Number of Participants with sports injury after one-year follow-up measure: Type, location, duration, and return to sports in participants with injury at one-year follow up measure: Sports Specialization measure: History of sports-related injuries measure: Health-related quality of life: EQ-5D-Y measure: Y-Balance Test - dynamic balance test measure: Functional Movement Screen (FMS) measure: Hand-Held Dynamometer (HHD) measurement - Isometric Strength of the lower extremities muscle measure: Sport workload (hours per trainings or competition) measure: Peak Height Velocity measure: Sports discipline and position measure: Participants characteristics - Body Mass Index measure: Sports experience sex: ALL minimumAge: 8 Years maximumAge: 16 Years stdAges: CHILD facility: Department of Immunobiology and Environment Microbiology, Medical University of Gdańsk city: Gdańsk zip: 80-211 country: Poland lat: 54.35205 lon: 18.64637 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2023-01-15 uploadDate: 2024-04-22T03:58 filename: ICF_000.pdf size: 183809 hasResults: False
nctId: NCT06325215 id: SCaglar briefTitle: The Effect of Hydrocolloid to Prevent Nasal Injuries in Preterm Infants overallStatus: COMPLETED date: 2022-05-05 date: 2022-10-29 date: 2022-11-05 date: 2024-03-22 date: 2024-03-22 name: Istanbul University - Cerrahpasa (IUC) class: OTHER briefSummary: The aim of this study is to evaluate the effect of using hydrocolloid tapes in preventing pressure injuries on the nose and columella regions caused by non-invasive mechanical ventilation (NIMV) in preterm infants. conditions: Pressure Injury studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized Controlled Experimantal primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE maskingDescription: After providing information about the study to the parents of preterm newborns who met the inclusion criteria, informed consent forms were obtained without disclosing which group their babies would be assigned to. The research outcome measurements were recorded by two nurses working at NICU. Prior to the study, necessary training and information about the form and process were provided to the nurses. The data analysis was conducted by an independent statistician. whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 56 type: ACTUAL name: Hidrocolloid Bant measure: Neonatal Skin Condition Score measure: Pressure İnjury Staging Scale measure: Neonatal Skin Risk Assessment Scale sex: ALL minimumAge: 24 Weeks maximumAge: 37 Weeks stdAges: CHILD facility: Abide-i Hurriyet Cad. Istanbul University-Cerrahpaşa, Florence Nightingale Faculty of Nursing city: Istanbul zip: 34381 country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06325189 id: Rec-42336 briefTitle: Effects of Aerobic Interval Training on Fatigue Level and Functional Performance in Post Angioplasty Patients overallStatus: COMPLETED date: 2023-07-20 date: 2023-12-01 date: 2023-12-10 date: 2024-03-22 date: 2024-03-22 name: Riphah International University class: OTHER briefSummary: The goal of this randomized controlled trial is to determine the effects of aerobic interval training on levels of tiredness and functional performance in post-angioplasty patients. The main question it aims to answer is:
Be randomly assigned to either the control group (medication) or the experimental group (medication + aerobic interval training) Perform aerobic interval training for 30 minutes, three times a week, for six weeks (experimental group only) Complete pre and post-intervention assessments using the fatigue severity scale, the 6-minute walk test, and the one minute sit to stand test Researchers will compare the two groups to see if aerobic interval training leads to significant improvements in fatigue levels and functional performance. conditions: Coronary Artery Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: In this parallel-group randomized controlled trial (RCT), post-angioplasty patients will be assigned to either the control group (receiving standard medication) or the experimental group (receiving medication along with aerobic interval training). The study aims to evaluate the impact of aerobic interval training on fatigue levels and functional performance in these patients. primaryPurpose: TREATMENT masking: SINGLE maskingDescription: The study was single-blinded, as assessors of the study were kept blind to the intervention group to which the participant was allocated. whoMasked: OUTCOMES_ASSESSOR count: 47 type: ACTUAL name: Aerobic Interval Training measure: Fatigue Severity Scale measure: Six Minute Walk Test measure: 1 minute sit to stand: sex: ALL minimumAge: 40 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Gulab Devi Chest Hospital city: Lahore state: Punjab zip: 54000 country: Pakistan lat: 31.558 lon: 74.35071 hasResults: False
nctId: NCT06325176 id: REC/RCR & AHS/23/0569 briefTitle: Comparative Effects of Cryotherapy and Infrared Light on Pain, Redness, and Healing of Episiotomy Wound overallStatus: RECRUITING date: 2024-03-20 date: 2024-10-01 date: 2024-10-15 date: 2024-03-22 date: 2024-04-05 name: Riphah International University class: OTHER briefSummary: The study will be a randomized clinical trial and will be conducted in Bahawalpur Victoria Hospital, Bahawalpur. The subjects (n=24) will be divided into two groups. Group A will include 12 postnatal women and for treatment, cryotherapy will be applied for 20 minutes. Group B will include 12 women and receive infrared light, an infrared lamp will be put at a distance of 45 cm from the perineum, and the heat produced with 230 volts for twenty minutes. The participant will be checked after the first five minutes to make sure that she is not being burned. This procedure will be done twice a day for 7 consecutive days. conditions: Episiotomy Wound studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 20 type: ESTIMATED name: Cryotherapy name: Infrared light therapy measure: Numeric Pain Rating Scale measure: The standardized REEDA scale: sex: FEMALE minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: Bahawalpur Victoria Hospital(BVH) status: RECRUITING city: Bahāwalpur state: Punjab zip: 63100 country: Pakistan name: Ghulam Fatima, PhD* role: CONTACT phone: 03034073057 email: ghulam.fatima@riphah.edu.pk lat: 29.4 lon: 71.68333 hasResults: False
nctId: NCT06325163 id: MIU-IRB-2223-219 briefTitle: Accuracy of Artificial Intelligence Technology in Detecting Number of Root Canals in Human Mandibular First Molars Obturated and Indicated for Retreatment: Diagnostic Accuracy Experimental Study overallStatus: COMPLETED date: 2023-01-25 date: 2023-10-02 date: 2023-10-10 date: 2024-03-22 date: 2024-03-22 name: Misr International University class: OTHER briefSummary: evaluate the accuracy of new AI technology for detecting root canals in mandibular first molars retreatment cases in comparison to dentist clinical access cavity and CBCT imaging. conditions: Missed Canals studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SEQUENTIAL primaryPurpose: DIAGNOSTIC masking: NONE count: 35 type: ACTUAL name: CBCT name: clinical examination under dental operating microscope name: canal detection AI software (diagnocat) measure: Number of canals measure: linear morphological variations in failed cases sex: ALL minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: Misr International University city: Cairo country: Egypt lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06325150 id: STUDY00008572 briefTitle: The Impact of Light Exposure on Cognitive Function in Classrooms overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-02-01 date: 2028-02-01 date: 2024-03-22 date: 2024-03-22 name: Michigan State University class: OTHER briefSummary: Humans are constantly exposed to a variety of light types, created naturally or through artificial means. Light exposure captured by the eyes impacts many physiological functions in humans, including but not limited to cognitive output, fatigue levels, and mood regulation. The level of impact on cognitive learning from different types of light on undergraduate adult students remains unclear. conditions: Healthy studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: This study will test the effect of light emitting glasses, vs placebo, vs no-glasses to attention in college students. This is a crossover study, where participants will be randomly assigned to one of three groups, and tested in random order. The students will be tested on 2 or 3 different conditions (no glasses, placebo or light emitting glasses). The assignment to each of the groups, and the order of the intervention (+/- glasses) will be randomized.
Note-light emitting glasses are not FDA regulated. Because light emitting glasses can change physiology, this is considered a phase 1 clinical trial. primaryPurpose: BASIC_SCIENCE masking: SINGLE whoMasked: INVESTIGATOR count: 300 type: ESTIMATED name: Light emitting glasses measure: Assessment of attention measure: Determine how time of day impacts attention sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Michigan State University city: East Lansing state: Michigan zip: 48824 country: United States name: Hanne M Hoffmann, PhD role: CONTACT phone: 517-353-1415 email: hanne@msu.edu lat: 42.73698 lon: -84.48387 hasResults: False
nctId: NCT06325137 id: RC 24/2022 briefTitle: Transcriptome Analysis in Idiopathic Nephrotic Syndrome: Steroid Responsiveness overallStatus: RECRUITING date: 2023-03-16 date: 2025-03 date: 2025-03 date: 2024-03-22 date: 2024-03-22 name: IRCCS Burlo Garofolo class: OTHER briefSummary: Idiopathic nephrotic syndrome (INS) affects the glomerular barrier by damaging the podocytes with foot process effacement, leading to a pathological increase of permeability and protein loss. INS classification is based on the clinical response to glucocorticoid (GC) therapy. When GCs treatment fails to induce remission in a four-six weeks course, patients are defined as affected with steroid-resistant nephrotic syndrome (SRNS).
Of great interest is the research of a molecular biomarker to predict steroid resistance, a predictor that is not yet available. Among the candidate biomarkers, pharmacogenomic determinants are promising, even if available studies are still limited. Among these, some epigenetic factors have been previously suggested. Data obtained in animal models suggests that nucleotide-binding oligomerization domain-like receptors (NOD-like receptor) pyrin domain containing 3 (NLRP3) inflammasome can be deregulated in a wide variety of glomerular diseases, including those causing INS. Another potential marker involved in steroid response is the long noncoding RNA GAS5. Data reported in the literature indicate that abnormal levels of GAS5 in peripheral blood mononuclear cells (PBMCs) may alter steroid effectiveness in autoimmune diseases, such as inflammatory bowel disease.