hackint0sh/New-Dataset huggingface dataset:
There is little information about the efficacy and safety of iron chelation in MDS patients. This audit wants to evaluate the effect of iron toxicity on treatment-related mortality in untreated, adult MDS or CMML patients during and after treatment with myeloablative conditioning (MAC) and reduced intensity conditioning (RIC) allo-HSCT, by prospectively collecting data from 200 MDS or CMML patients from 2009 onwards. conditions: MDS conditions: CMML studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 222 type: ACTUAL measure: non-relapse mortality (treatment related mortality). measure: treatment-related toxic effects measure: relapse rate measure: event-free survival measure: overall survival sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Antwerp University Hospital (UZA) city: Antwerp zip: 2650 country: Belgium lat: 51.21989 lon: 4.40346 facility: University Hospital Gasthuisberg city: Leuven zip: 3000 country: Belgium lat: 50.87959 lon: 4.70093 facility: University of Liege city: Liege zip: 4000 country: Belgium lat: 50.63373 lon: 5.56749 facility: Charles University Hospital city: Pilsen zip: 304 60 country: Czechia lat: 49.74747 lon: 13.37759 facility: University Hospital city: Essen zip: 45122 country: Germany lat: 51.45657 lon: 7.01228 facility: University Hospital Leipzig city: Leipzig zip: 04103 country: Germany lat: 51.33962 lon: 12.37129 hasResults: False
nctId: NCT06267885 id: Children NOF fracture fixation briefTitle: Fixation of Fracture Neck of Femur in Children overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-02 date: 2026-03 date: 2024-02-20 date: 2024-02-20 name: Assiut University class: OTHER briefSummary: Find the best way for fixation of fracture neck of femur in children either by cannulated screws or wagner's technique conditions: Fracture Neck of Femur studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 42 type: ESTIMATED name: Cannulated screws vs wagner's technique measure: The better method for fixation of fracture neck of femur sex: ALL minimumAge: 1 Year maximumAge: 14 Years stdAges: CHILD facility: Assiut university city: Assiut country: Egypt name: Mina Maged role: CONTACT lat: 27.18096 lon: 31.18368 hasResults: False
nctId: NCT06267872 id: HVTN 309 briefTitle: A Clinical Trial in Adult Participants Without HIV and in Overall Good Health to Evaluate the Safety and Immunogenicity of CD4BS CH505M5 Pr-NP1 Followed by CH505 TF chTrimer Boost Both Adjuvanted With Either Lipid Nanoparticles (LNPs) or 3M-052-AF + Alum overallStatus: NOT_YET_RECRUITING date: 2024-05-31 date: 2025-12-12 date: 2026-07-11 date: 2024-02-20 date: 2024-02-20 name: National Institute of Allergy and Infectious Diseases (NIAID) class: NIH name: National Institutes of Health (NIH) name: Department of Health and Human Services name: Duke University name: Access to Advanced Health Institute (AAHI) briefSummary: This is a multicenter, open-label, phase 1 clinical trial to test two human immunodeficiency virus (HIV) vaccines with two adjuvants. An adjuvant is an ingredient used with some vaccines that may help people make an immune response. HIV is the virus that causes acquired immunodeficiency syndrome (AIDS).
nctId: NCT06267859 id: No. 2 of 2023/11/7 briefTitle: Development of Methods for Effective Treatment and Improvement of Common Somatic Diseases in Children overallStatus: RECRUITING date: 2023-11-08 date: 2033-12-30 date: 2034-01-30 date: 2024-02-20 date: 2024-02-28 name: Tashkent Pediatric Medical Institute class: OTHER briefSummary: The goal of the clinical study is to clarify the course of common congenital, infectious, and non-infectious diseases in children living in Uzbekistan, and to develop methods for their treatment and rehabilitation.
* Development of modern methods of treatment and rehabilitation of children. conditions: Respiratory Diseases conditions: Congenital Heart Defects studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: identification of children from the group of "frequently ill children" primaryPurpose: SUPPORTIVE_CARE masking: SINGLE maskingDescription: working with children from the "frequently ill children" group whoMasked: PARTICIPANT count: 110 type: ESTIMATED name: The use of a combination of microelements and vitamins against the background of physiotherapy measure: Working with archival documentation. measure: Formation of a group of patients to study immunity and the antioxidant system in venous blood. measure: Clinical scientific research. measure: Clinical trial evaluation. sex: ALL minimumAge: 3 Days maximumAge: 15 Years stdAges: CHILD facility: Turdieva Shokhida Tolkunovna status: RECRUITING city: Tashkent state: Yunus-obad District zip: 100140 country: Uzbekistan name: Shokhida T Turdieva, M.D., D.Sc. role: CONTACT phone: +998935872570 email: Shohidahon69@mail.ru name: Kholida B Abdurashidova role: CONTACT phone: +998935092934 email: otdel.nayka@mail.ru name: Gulmira R Nasirova, Ph.D. role: SUB_INVESTIGATOR lat: 41.26465 lon: 69.21627 hasResults: False
nctId: NCT06267846 id: NBI-1070770-MDD2029 briefTitle: A Study to Evaluate the Efficacy and Safety of NBI-1070770 in Adults With Major Depressive Disorder overallStatus: RECRUITING date: 2024-03-20 date: 2025-09 date: 2025-12 date: 2024-02-20 date: 2024-04-12 name: Neurocrine Biosciences class: INDUSTRY briefSummary: To evaluate the efficacy, safety, and tolerability of NBI-1070770 compared to placebo on improving symptoms of depression in participants with major depressive disorder (MDD). conditions: Major Depressive Disorder studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 72 type: ESTIMATED name: NBI-1070770 name: Placebo measure: Change in Total Montgomery-Åsberg Depression Rating Scale (MADRS) Score from Baseline to Day 5 measure: Change in Total MADRS Score from Baseline at Postbaseline Timepoints sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Neurocrine Clinical Site status: RECRUITING city: Little Rock state: Arkansas zip: 72211 country: United States lat: 34.74648 lon: -92.28959 facility: Neurocrine Clinical Site status: RECRUITING city: Rogers state: Arkansas zip: 72758 country: United States lat: 36.33202 lon: -94.11854 facility: Neurocrine Clinical Site status: RECRUITING city: Lemon Grove state: California zip: 91945 country: United States lat: 32.74255 lon: -117.03142 facility: Neurocrine Clinical Site status: RECRUITING city: Long Beach state: California zip: 90806 country: United States lat: 33.76696 lon: -118.18923 facility: Neurocrine Clinical Site status: RECRUITING city: Hollywood state: Florida zip: 33024 country: United States lat: 26.0112 lon: -80.14949 facility: Neurocrine Clinical Site status: RECRUITING city: Decatur state: Georgia zip: 30030 country: United States lat: 33.77483 lon: -84.29631 facility: Neurocrine Clinical Site status: RECRUITING city: Savannah state: Georgia zip: 31405 country: United States lat: 32.08354 lon: -81.09983 facility: Neurocrine Clinical Site status: RECRUITING city: Gaithersburg state: Maryland zip: 20877 country: United States lat: 39.14344 lon: -77.20137 facility: Neurocrine Clinical Site status: RECRUITING city: North Canton state: Ohio zip: 44730 country: United States lat: 40.87589 lon: -81.40234 facility: Neurocrine Clinical Site status: RECRUITING city: Houston state: Texas zip: 77008 country: United States lat: 29.76328 lon: -95.36327 hasResults: False
nctId: NCT06267820 id: 2010 briefTitle: Postoperative Pain Control by Adding Ketorolac to Bupivacaine in Transversus Abdominis Plane Block in Children overallStatus: COMPLETED date: 2023-06-01 date: 2023-12-01 date: 2023-12-10 date: 2024-02-20 date: 2024-02-20 name: Sohag University class: OTHER briefSummary: Control of of pain in children is fundamental. TAP block is associated with less side effects compared with other neuraxial techniques especially when done under ultrasound guidance.
Group (T) (n =45): received ultrasound guided TAP block with bupivacaine 0.25% (0.5 ml/kg) conditions: Postoperative Pain, Acute studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 90 type: ACTUAL name: Bupivacain name: Ketorolac measure: 1st analgesic requirement measure: Number of patients who requested analgesia measure: heart rate measure: Total rescue analgesia measure: Satisfaction of the parents regarding their children analgesia measure: Number of children in each group who required analgesia in the first 24 h postoperatively measure: blood pressure sex: ALL minimumAge: 6 Years maximumAge: 12 Years stdAges: CHILD facility: Fouad Ibrahim Soliman city: Sohag zip: 52514 country: Egypt lat: 26.55695 lon: 31.69478 hasResults: False
nctId: NCT06267807 id: 114369 id: NL84520.091.23 type: OTHER domain: Protocol ID METC briefTitle: Lymphatic Phenotype in Noonan Syndrome Spectrum Disorders acronym: LENS overallStatus: RECRUITING date: 2024-03-27 date: 2025-03-13 date: 2025-06-01 date: 2024-02-20 date: 2024-02-20 name: Radboud University Medical Center class: OTHER briefSummary: To get a better insight into the central conducting lymphatic system in adult volunteers with Noonan Syndrome (NS) without clinical symptoms or signs of lymphatic disease compared to NS and CardioFacioCutaan syndrome patients with severe lymphatic disease conditions: Lymphatic System Disorders Congenital conditions: Lymphatic Diseases conditions: Noonan Syndrome conditions: Lymphatic Disease studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 15 type: ESTIMATED name: Dynamic contrast-enhanced lymphangiography measure: Central lymphatic system anatomy and flow descriptive parameters. measure: Diameter Thoracic duct measure: Lymph flow velocity measure: Demographics age measure: Demographics gender measure: Demographics measure: Demographics weight measure: Demographics clinical history measure: Demographics genetic background sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Radboudumc status: RECRUITING city: Nijmegen state: Gelderland zip: 6500 HB country: Netherlands name: Lotte ER Kleimeier, Msc role: CONTACT phone: 024036106873 email: lotte.kleimeier@radboudumc.nl lat: 51.8425 lon: 5.85278 hasResults: False
nctId: NCT06267794 id: ODISEA Study briefTitle: Prolonged Release Pirfenidone Versus Placebo in Compensated Cirrhosis. acronym: ODISEA overallStatus: COMPLETED date: 2015-06-26 date: 2021-12-30 date: 2023-03-24 date: 2024-02-20 date: 2024-02-20 name: Jorge L Poo class: OTHER briefSummary: This will be a multicenter, double-blind clinical trial to evaluate the safety and efficacy of two doses of prolonged release pirfenidone, compared against placebo plus conventional therapy in patients with compensated liver cirrhosis. The study will be conducted in compliance with International Standard good clinical practices (GCPs) and the Declaration of Helsinki. The protocol is approved by a local Institutional Review Board and registered in clinical trials.gov. conditions: Liver Fibrosis conditions: Cirrhosis, Liver conditions: Chronic Liver Disease studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Double blind, placebo-controlled multicenter study primaryPurpose: TREATMENT masking: TRIPLE maskingDescription: Placebo will be identical to medication.
The person responsible for the medication at the research site will contact the Randomization center, where the treatment will be assigned to the patient. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 180 type: ACTUAL name: Pirfenidone 1200 mg name: Pirfenidone 1800 mg name: Placebo measure: Change in liver fibrosis measure: Clinical side effects measure: Improvement in Child Pugh score measure: Improvement in MELD score measure: Improvement in bilirrubin and albumin measure: Improvement in prothrombin time measure: Improvement in liver enzymes measure: Improvement in EuroQol Visual analog scales measure: Improvement in EuroQol five dimensions Scale measure: Improvement in modified fatigue impact scale (MFIS) sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06267781 id: TRANSPLANT-PRO briefTitle: RRMS: Disease PROgression and Myeloid Profiling After Bone Marrow TRANSPLANTation and Second Line Therapies acronym: TRANSPLANTPRO overallStatus: RECRUITING date: 2022-09-02 date: 2027-09-02 date: 2027-09-02 date: 2024-02-20 date: 2024-02-20 name: IRCCS San Raffaele class: OTHER briefSummary: To study whether highly effective therapies can halt disease progression in people with multiple sclerosis by modulating the peripheral myeloid landscape. conditions: Multiple Sclerosis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30 type: ESTIMATED measure: Number of fading/disappearing paramagnetic rim lesions (PRLs) measure: Surrogate biomarkers of disease progression (MSFC) measure: Surrogate biomarkers of disease progression (sNfL) measure: Surrogate biomarkers of disease progression (RNFL) measure: Surrogate biomarkers of disease progression (cortical lesions) measure: Surrogate biomarkers of disease progression (atrophy) measure: Changes in myeloid landscape sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IRCCS San Raffaele status: RECRUITING city: Milan zip: 20132 country: Italy name: Massimo Filippi, MD role: CONTACT phone: 00390226433054 email: filippi.massimo@hsr.it name: Anna A. Bellini, MD role: CONTACT phone: 00390226432154 email: bellini.anna@hsr.it lat: 45.46427 lon: 9.18951 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2022-05-03 uploadDate: 2024-02-15T03:19 filename: Prot_SAP_000.pdf size: 10630791 hasResults: False
nctId: NCT06267768 id: REC Reference No.:HE-OT2023/13 id: Proj.Ref.No.: 2023/3007-R7052 type: OTHER_GRANT domain: Research Donation Fund, Hong Kong Metropolitan University briefTitle: The Effects of Inspiratory Pressures on Diaphragmatic Contraction in People After Stroke overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-11-30 date: 2025-11-30 date: 2024-02-20 date: 2024-03-27 name: Hong Kong Metropolitan University class: OTHER name: Shenzhen Second People's Hospital briefSummary: This is a cross-sectional study to determine the optimal inspiratory muscle training (IMT) intensity for stroke survivors. Participants will breathe through a pressure threshold inspiratory loading device with varying loads in random order. Each IMT intensity protocol consists of 10 breaths. During the test, accessory inspiratory muscle activity will be measured with surface electromyography (sEMG) and diaphragm thickness will be used to assessed with ultrasonography. Repeated-measures ANOVA will be used for statistical analysis to determine the most effective training intensity for future study. conditions: Stroke studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 130 type: ESTIMATED name: Various intensities of inspiratory muscle training measure: Diaphragmatic thickening fraction measure: Muscle activation of the sternocleidomastoid muscle measure: Perceived Exertion Borg scale sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2023-12-29 uploadDate: 2024-01-08T21:03 filename: Prot_SAP_000.pdf size: 563906 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2023-12-29 uploadDate: 2024-02-15T09:59 filename: ICF_001.pdf size: 197199 hasResults: False
nctId: NCT06267755 id: P.T.REC/012/004884 briefTitle: Efficacy of Extracorporeal Shockwave Therapy on Ultrasonography Changes of Upper Trapezius Myofascial Trigger Points in Patients With Non Specific Neck Pain acronym: MTP overallStatus: NOT_YET_RECRUITING date: 2024-02-20 date: 2024-08-30 date: 2024-08-30 date: 2024-02-20 date: 2024-02-20 name: Cairo University class: OTHER briefSummary: this study will be conducted to investigate the effect of Extracorporeal Shockwave Therapy on Ultrasonography Changes of Upper Trapezius Myofascial Trigger Points in Patients With Non Specific Neck Pain conditions: Neck Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: extracorporeal shockwave and traditional therapy primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: opaque sealed envelope whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Extracorporeal Shockwave therapy name: Traditional physical therapy measure: muscle thickness measure: hypoechoic area intensity measure: neck disability measure: pressure pain threshold measure: cervical range of motion measure: pain intensity sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06267742 id: CHN097 briefTitle: Clinical Trial to Evaluate MDW for Early Detection of Sepsis overallStatus: RECRUITING date: 2022-06-23 date: 2024-03-31 date: 2024-09-30 date: 2024-02-20 date: 2024-02-28 name: Beckman Coulter, Inc. class: INDUSTRY name: Peking Union Medical College Hospital name: West China Hospital name: Second Affiliated Hospital, School of Medicine, Zhejiang University briefSummary: This study is intended to clinically verify Monocyte Distribution Width (MDW) parameter of DxH 900 Hematology Analyzer for use in early detection and risk assessment of sepsis, severe sepsis, and septic shock in critically ill patients in Emergency Department (ED). This study is also aimed to provide study supporting data for the product to be marketed in China. conditions: Sepsis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 2200 type: ESTIMATED name: Complete Blood Count (CBC) with Differential measure: sensitivity, specificity sex: ALL minimumAge: 18 Years maximumAge: 89 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Peking Union Medical College Hospital status: RECRUITING city: Beijing country: China name: Huadong Zhu, MD role: CONTACT lat: 39.9075 lon: 116.39723 facility: West China Hospital, Sichuan University status: RECRUITING city: Chengdu country: China name: Yaxiong Zhou, MD role: CONTACT lat: 30.66667 lon: 104.06667 facility: The Second Affiliated Hospital of Zhejiang University School of Medicine status: RECRUITING city: Hangzhou country: China name: Mao Zhang, MD role: CONTACT lat: 30.29365 lon: 120.16142 hasResults: False
nctId: NCT06267716 id: 274-2023 briefTitle: Pericapsular Nerve Block and Iliopsoas Fascial Plane Block in Hip Surgery overallStatus: RECRUITING date: 2024-02-23 date: 2024-07-30 date: 2024-08-30 date: 2024-02-20 date: 2024-02-28 name: Haseki Training and Research Hospital class: OTHER briefSummary: This prospective randomized interventional study aims to compare the effects of two peripheral nerve blocks, the periencapsular nerve block (PENG) and iliopsoas block (IPB), on analgesia and motor function after hip surgery.
Researchers will compare the total amount of rescue analgesia and numeric rating scale with accompanying evaluating motor function at the same time intervals within 24 hour. conditions: Hip Fractures conditions: Peripheral Nerve Block studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: prospective randomized standardized triple-blind primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE maskingDescription: The participants under general anaesthesia and the orthopaedic surgeon responsible for the study will be blinded to the study groups and the specific block procedures. This surgeon will serve as the sole evaluator of postoperative outcomes. Intraoperative results will be recorded by the anaesthesia technician, who is present in the operating room and unaware of the block procedures. Moreover, the data analysis will be conducted before the data are unblinded. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: PENG block name: IPB measure: postoperative motor block measure: pain scores measure: total analgesia, intraoperative measure: total rescue analgesia sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Haseki Training and Research Hospital status: RECRUITING city: Istanbul state: Sultangazi zip: 34000 country: Turkey name: Berna Caliskan role: CONTACT phone: +905067108770 email: caliskan.b@gmail.com lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06267703 id: 2023-01939_VR briefTitle: Multi-omics Analyses on Etiology and Early Detection of Stomach Cancer Precursor Lesions overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-01 date: 2026-12-31 date: 2026-12-31 date: 2024-02-20 date: 2024-02-21 name: Karolinska Institutet class: OTHER briefSummary: The overall aim is to utilize multi-omics approach to identify novel etiopathogenesis and early detection biomarkers for stomach cancer precursor lesions. To achieve this aim, first the investigators will use stored serum samples to perform metabolomics profiling among 12,599 twin subjects, among whom 1034 were deemed to have chronic atrophic gastritis based on measured pepsinogen I and II levels. Logistic regression will be used to search for metabolites related to the risk of chronic atrophic gastritis. Second, the investigators will further measure serum proteome by using two quantitatively precise proteomics assays, among the above-mentioned twin subjects. Identified protein biomarkers will be combined with metabolomics biomarkers to create a prediction model for chronic atrophic gastritis. The results will hopefully improve our understanding of the etiological factors and provide promising early detection biomarkers for stomach cancer precursor lesions. conditions: Chronic Atrophic Gastritis studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: CROSS_SECTIONAL count: 12599 type: ACTUAL name: Metabolomic profiling measure: Chronic atrophic gastritis sex: ALL minimumAge: 46 Years maximumAge: 97 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Karolinska Institutet city: Solna state: Stockholm zip: 17165 country: Sweden lat: 59.36004 lon: 18.00086 hasResults: False
nctId: NCT06267690 id: SYSUFAH2021025 briefTitle: A CT-based Radiomics Model to Predict Survival-graded Fibrosis in PDAC overallStatus: COMPLETED date: 2021-01-13 date: 2023-08-31 date: 2023-08-31 date: 2024-02-20 date: 2024-02-20 name: First Affiliated Hospital, Sun Yat-Sen University class: OTHER briefSummary: Tumor fibrosis plays an important role in chemotherapy resistance in pancreatic ductal adenocarcinoma (PDAC), however there remains a contradiction in the prognostic value of fibrosis. We aimed to investigate the relationship between tumor fibrosis and survival in patients with PDAC, classify patients into high- and low-fibrosis groups, and develop and validate a CT-based radiomics model to non-invasively predict fibrosis before treatment. conditions: Pancreatic Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 295 type: ACTUAL name: surgery measure: fibrosis sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Shi Siya city: Guangzhou state: Guangdong zip: 510000 country: China lat: 23.11667 lon: 113.25 hasResults: False