hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06356428 id: KARYÖN-DR briefTitle: Psychometric Properties and Cross-cultural Adaptation of the Turkish Version of Physcian Attitudes Toward Cardiac Rehabilitation and Referral Scale-Revised (PACRR-R) overallStatus: NOT_YET_RECRUITING date: 2024-05-13 date: 2025-05-13 date: 2025-08-13 date: 2024-04-10 date: 2024-04-15 name: Karamanoğlu Mehmetbey University class: OTHER briefSummary: Research has reported that the reasons for low implementation of CR are multifactorial at the health system, physician and patient levels. It has also been found that patients are more likely to initiate CR if physicians strongly and positively promote the importance of CR participation. Unfortunately, there are insufficient and ineffective data on CR, referral to CR and both clinical and cost-effectiveness outcomes of CR in Turkey. In this context, it is important to examine more objectively from the perspective of physicians who play a key role in referring patients to CR. However, in our country, there is no relatively objective measurement tool to evaluate physicians' attitudes towards CR. Therefore, this study aims to adapt the original "Physician Attitudes towards Cardiac Rehabilitation and Referral Scale-Revised (PACRR-R)" into Turkish and to examine its psychometric properties. conditions: Physician's Role studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 100 type: ESTIMATED name: Physcian Attitudes toward Cardiac Rehabilitation and Referral Scale-Revised (PACRR-R) measure: Physician Attitudes toward Cardiac Rehabilitation and Referral (PACRR)-Revised Scale Score sex: ALL minimumAge: 25 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06356415 id: Dex Dex in infraclavicular briefTitle: Infraclavicular Brachial Plexus Block With Bupivacaine Alone or With Both Dexmedetomidine and Dexamethasone overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-08-30 date: 2024-09-30 date: 2024-04-10 date: 2024-04-10 name: Suez Canal University class: OTHER briefSummary: Upper-extremity regional anesthetic techniques, using brachial plexus blockade, have been shown to reduce adverse effects related to opioid administration, improve patient satisfaction, and provide significantly improved analgesia immediately following these surgeries. Many medications have been investigated to extend and enhance long-acting local anesthetics' (LA) analgesic effects. Currently, dexamethasone and dexmedetomidine have been studied, looking for an optimal long-lasting single-shot nerve block. In general, adjuvants have been used in peripheral nerve blocks to accelerate onset, decrease plasmatic absorption and secondary toxic effects, and prolong the block effects. conditions: Upper Extremity Injury studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE maskingDescription: The sealed-envelope technique will be used. An assistant who is not involved in patient care will make and combine bupivacaine, whether it contains adjuvants or not. Thus, all patients, operators, and outcome assessors remain blinded to the nature of the perineural adjuvant whoMasked: PARTICIPANT count: 40 type: ESTIMATED name: Bupivacaine injection name: Bupivacaine+ Dexamethasone+ Dexmedetomidine measure: Onset of sensory block sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06356402 id: 8510224SMCPD briefTitle: An Investigation of the Efficacy of OHEM for Improving Oral Hygiene in Children overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-08 date: 2024-12 date: 2024-04-10 date: 2024-04-10 name: Ziauddin University class: OTHER name: Universiti Sains Malaysia briefSummary: This pilot study evaluates the feasibility of conducting a larger Randomized Controlled Trial to compare three oral health education delivery methods to a control group. Except for the control group, mothers in the three intervention groups will receive the same oral health education based on the OHEM module but differ in the delivery methods, namely lecture, exhibition, and demonstration. All groups will receive a booklet and oral hygiene kits and be instructed to educate their children at home. Pre- and post-intervention assessments include the satisfaction of participants, the researchers' evaluation and cost of the trial, oral hygiene status, and the knowledge of the parents and children. conditions: Dental Plaque conditions: Gingivitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: SINGLE whoMasked: PARTICIPANT count: 540 type: ESTIMATED name: Oral Health Educational Module for Mothers (OHEM) lecture name: Oral Health Educational Module for Mothers (OHEM) exhibition name: Oral Health Educational Module for Mothers (OHEM) demonstration measure: Satisfaction of participants: measure: Recruitment and participation of participants in the study measure: Cost of the trial measure: Dental plaque scores measure: Gingival scores measure: Oral health KAP scores measure: Oral health behaviors measure: Oral health-related quality of life using Oral health impact profile-14 sex: ALL minimumAge: 12 Years maximumAge: 40 Years stdAges: CHILD stdAges: ADULT facility: Primary Healthcare Center Gulshan-e-Sikandarabad Shireen Jinnah Colony city: Karachi country: Pakistan name: Sidra Mohiuddin, MDS role: PRINCIPAL_INVESTIGATOR lat: 24.8608 lon: 67.0104 hasResults: False
nctId: NCT06356389 id: JX11502MA-Ib-II briefTitle: A Clinical Trial to Evaluate Safety, Tolerance and Pharmacokinetics of JX11502MA Capsule in Patients With Schizophrenia. overallStatus: COMPLETED date: 2022-03-02 date: 2022-12-27 date: 2023-01-28 date: 2024-04-10 date: 2024-04-10 name: Zhejiang Jingxin Pharmaceutical Co., Ltd. class: INDUSTRY name: Shanghai Mental Health Center briefSummary: A multicenter, randomized, double-blind, placebo-controlled, dose-increasing phase Ib/II clinical trial to evaluate the safety, tolerance and pharmacokinetic characteristics of JX11502MA capsules administered multiple times in patients with schizophrenia conditions: Schizophrenia studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Double-Blind whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 60 type: ACTUAL name: JX11502MA name: Placebo measure: Incidence of treatment-emergent adverse events (TEAEs) measure: Change From Baseline in Positive and Negative Syndrome Scale (PANSS) Total Score at Day 28 measure: Change From Baseline in Positive and Negative Syndrome Scale (PANSS) Positive Score at Day 28 measure: Change From Baseline in Positive and Negative Syndrome Scale (PANSS) Negative Score at Day 28 measure: Change From Baseline in Clinical Global Impression - Severity (CGI-S) Score at Day 28 measure: Tmax measure: Css_min measure: Css_max measure: Css_av measure: AUC0-t,ss measure: AUC0-∞,ss measure: AUCtau,ss measure: t1/2 sex: ALL minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: Shanghai Mental Health Center city: Shanghai state: Shanghai zip: 201109 country: China lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06356376 id: UAarhus_AGK_MNG_2 briefTitle: The Effects of Pain and Pain Relief on Peripheral Nerve Excitability overallStatus: RECRUITING date: 2023-12-20 date: 2024-04-30 date: 2024-04-30 date: 2024-04-10 date: 2024-04-10 name: University of Aarhus class: OTHER name: Lundbeck Foundation briefSummary: This study will assess changes in nerve excitability of C-fibers, and changes in sympathetic or parasympathetic tone, when the subject experiences pain and pain relief.
The investigators will continuously measure blood pressure, heart rate, respiration rate, gastric motility, sympathetic skin response and C-fiber excitability while using thermal stimuli before and after an analgesic. conditions: Analgesia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30 type: ESTIMATED name: Heat Stimulation measure: C-fiber excitability measure: Action potential duration (ms) measure: Action potential amplitude (V) measure: Heart-rate variability (ms) measure: Blood pressure variability (mmHg) measure: Sympathetic Skin Response (V) sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Danish Pain Research Center status: RECRUITING city: Aarhus N zip: 8200 country: Denmark name: Alexander G Kristensen, MD,PhD role: CONTACT phone: +45 93 52 28 64 email: alexgramm@clin.au.dk lat: 56.15674 lon: 10.21076 hasResults: False
nctId: NCT06356363 id: 2023_RIPH_005_OncoPREMs briefTitle: Development of a Questionnaire on Patients' Perception of Their Oncology Care Pathway (Onco-PREMs) acronym: OncoPREMs overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-11-01 date: 2025-11-01 date: 2024-04-10 date: 2024-04-10 name: Institut Jean-Godinot class: OTHER name: Université de Reims Champagne-Ardenne briefSummary: Healthcare systems are evolving, giving increasing prominence to the patient-centered model, accompanied by objective and perceived outcomes.
In oncology, the collection of patient-perceived quality regarding their care pathway would enable better coordination of their care. While a few initiatives have emerged in the field of PREMs, the development of a reliable questionnaire assessing patient perception of their care pathway in oncology remains a challenge. conditions: Cancer studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 500 type: ESTIMATED name: Data collection measure: Psychometric validation sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06356350 id: IUC_jia_scoliosis_gait briefTitle: Exercise Programs on Gait in Children With Scoliosis Diagnosed JIA overallStatus: RECRUITING date: 2024-04-01 date: 2024-10-01 date: 2024-11-01 date: 2024-04-10 date: 2024-04-19 name: Istanbul University - Cerrahpasa (IUC) class: OTHER briefSummary: Juvenile Idiopathic Arthritis (JIA) is one of the common chronic diseases in childhood. Problems such as weakness or pain may occur in JIA, especially in the joints and the muscles around the trunk (1). These conditions may lead to abnormal displacement of the center of gravity, deterioration of biomechanics, and muscle imbalance in children with JIA (2, 3). All these situations can lead to scoliosis, which we often encounter in children with JIA. Current studies describing various 3-dimension (3D) exercise methods (SEAS, Schroth, Dobomed, BSPTS, Side-shift, Lyon, etc.) effective on scoliosis (4). However, no study was found in the literature that searching the effects of these exercise methods on gait parameters in children with scoliosis diagnosed JIA. conditions: Scoliosis Idiopathic conditions: Juvenile Idiopathic Arthritis conditions: Gait, Frontal studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 50 type: ESTIMATED name: Conventional exercises name: 3D exercises measure: ATR measure: Cobb angle measure: Maximum Loading measure: Center of mass displacement measure: Walking speed sex: ALL minimumAge: 6 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Istanbul University-Cerrahpasa status: RECRUITING city: Istanbul country: Turkey name: Gökçe Leblebici role: CONTACT phone: 05397395718 email: leblebicigokce@gmail.com lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06356337 id: STUDY-22-01199 briefTitle: A Light Exposure Tracker Designed to Improve Circadian Rhythms - Aim 1 overallStatus: RECRUITING date: 2024-02-22 date: 2024-08-31 date: 2025-08-31 date: 2024-04-10 date: 2024-04-10 name: Icahn School of Medicine at Mount Sinai class: OTHER briefSummary: The purpose of this research study is to investigate the relationship between light and circadian rhythms. Twenty healthy older adults will be recruited to participate in a randomized, cross-over study, where an active lighting intervention designed to maintain entrainment and a control intervention designed not to entrain will be tested. conditions: Alzheimer's Disease conditions: Mild Cognitive Impairment studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 20 type: ESTIMATED name: Light goggles name: Orange glasses measure: Saliva samples for melatonin levels measure: Light exposure using the Speck measure: Sleep time using actigraphy sex: ALL minimumAge: 55 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Light and Health Research Center status: RECRUITING city: Menands state: New York zip: 12204 country: United States name: Barbara Plitnick role: CONTACT phone: 518-242-4603 email: barbara.plitnick@mountsinai.org name: Mariana Figueiro role: PRINCIPAL_INVESTIGATOR lat: 42.69202 lon: -73.72456 hasResults: False
nctId: NCT06356324 id: 2021-13347 briefTitle: The Effects of Music and Television on Intraoperative Hypertensive Events in Cataract Surgery overallStatus: COMPLETED date: 2021-10-18 date: 2024-01-31 date: 2024-04-01 date: 2024-04-10 date: 2024-04-10 name: Montefiore Medical Center class: OTHER briefSummary: This study investigates whether television viewing or music listening can reduce pre-operative anxiety and improve surgical outcomes for patients undergoing cataract surgery. It aims to determine the effectiveness of these interventions compared to a control group and assess their impact on physiological markers of anxiety as well as the incidence of intra-operative hypertensive events.
2. Does listening to music before cataract surgery decrease intraoperative hypertensive events and/or pre-operative anxiety in patients? conditions: Anxiety conditions: Intraoperative Hypertension conditions: Cataract studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Participants assigned to one of three groups: music listening, tv viewing, or control (waiting with ambient noise) primaryPurpose: PREVENTION masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 650 type: ACTUAL name: Music Intervention name: Television Intervention measure: Intraoperative hypertensive event measure: Change in VAS-A measurements for Anxiety measure: Change in Heart Rate measurements for Anxiety measure: Change in Blood pressure measurements for Anxiety sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Montefiore Medical Center city: New York state: New York zip: 10467 country: United States lat: 40.71427 lon: -74.00597 hasResults: False
nctId: NCT06356311 id: 2870-015 id: 2023-505423-31 type: REGISTRY domain: EU CT id: U1111-1291-7109 type: OTHER domain: UTN id: MK-2870-015 type: OTHER domain: Merck Id briefTitle: A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015) overallStatus: NOT_YET_RECRUITING date: 2024-05-08 date: 2027-01-04 date: 2028-05-05 date: 2024-04-10 date: 2024-04-29 name: Merck Sharp & Dohme LLC class: INDUSTRY briefSummary: This study will compare how safe and effective sacituzumab tirumotecan is versus the treatment of physician's choice (TPC) in participants with advanced/metastatic gastroesophageal adenocarcinoma. The primary hypothesis of this study is sacituzumab tirumotecan is superior to TPC with respect to Overall Survival (OS). conditions: Gastroesophageal Cancer studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 450 type: ESTIMATED name: Sacituzumab tirumotecan name: Trifluridine-Tipiracil name: Irinotecan name: Paclitaxel name: Docetaxel measure: Overall Survival (OS) measure: Progression-free survival (PFS) measure: Objective Response Rate (ORR) measure: Duration of Response (DOR) measure: Number of Participants Who Experience an Adverse Event (AE) measure: Number of Participants Who Discontinue Study Intervention Due to an AE sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06356298 id: MCHH_004 briefTitle: Flexible Reinforced Laryngeal Mask Airway Versus Endotracheal Tube for Childhood Adenotonsillectomy overallStatus: COMPLETED date: 2023-08-01 date: 2023-12-31 date: 2023-12-31 date: 2024-04-10 date: 2024-04-24 name: Maternal and Child Health Hospital of Hubei Province class: OTHER briefSummary: The goal of this clinical trial is to compare the airway management effects of flexible reinforced laryngeal mask and endotracheal tube in childhood adenotonsillectomy.
The investigators will compare FLMA with ETT to see if flexible reinforced laryngeal mask can be used safely and effectively in childhood adenotonsillectomy，and if there will be less severe adverse events in FLMA. conditions: Anesthesia Intubation Complication conditions: Airway conditions: Adenotonsillectomy conditions: Children studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 100 type: ACTUAL name: Airway Management: Flexible Reinforced Laryngeal Mask Airway name: Airway Management: Endotracheal Tube measure: Peak airway pressure measure: Petco2 measure: Ventilation leakage or not measure: Mean arterial pressure (MAP) measure: Heart rate (HR) measure: Recovery time measure: Extubation time measure: Dosage of anesthetic measure: Success of FLMA or ETT measure: Surgeon satisfaction measure: Adverse events sex: ALL minimumAge: 2 Years maximumAge: 10 Years stdAges: CHILD facility: Maternal and Child Health Hospital of Hubei Province city: Wuhan state: Hubei zip: 430000 country: China lat: 30.58333 lon: 114.26667 hasResults: False
nctId: NCT06356285 id: 6995049 briefTitle: Testing New Ways to Name Antimicrobial Resistance overallStatus: NOT_YET_RECRUITING date: 2024-04-10 date: 2024-06-01 date: 2024-06-01 date: 2024-04-10 date: 2024-04-10 name: Imperial College London class: OTHER name: The Behavioural Insights Team briefSummary: This study aims to investigate the public's views on antibiotics and the impact of different ways to name the potential consequences of antibiotics not working in the future. It is known that current ways to name this don't resonate well with the public, and the study team have worked with members of the public through focus groups and community workshops to develop new ways of describing this in a process of co-design. This study aims to test four different ways of presenting this potential crisis to the public, some of which are new communication strategies designed by the public themselves, to evaluate which are the most memorable and investigate the impact on behaviour change.
Is it anticipated that the survey will open in April 2024 and be open until recruitment of 4000 participants is complete. This is expected to take 4-6 weeks. conditions: Antimicrobial Resistance conditions: Attitude to Health studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: This study has been designed as a four-armed online randomised control trial (RCT). This will be conducted using Predictiv, an online platform for running behavioural experiments built by the Behavioural Insights Team The 4,000 participants will be randomised in a 1:1:1:1 ratio to one of four trial arms. primaryPurpose: OTHER masking: SINGLE maskingDescription: Participants will be blinded to the study arm that they have been assigned to. whoMasked: PARTICIPANT count: 4000 type: ESTIMATED name: Presentation of Antimicrobial Resistance measure: Attitudes towards Antimicrobial Resistance (Sentiment) measure: Comprehension measure: Intent measure: Recall measure: Impact on population sub-groups sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06356272 id: 19-006036 id: NCI-2024-00965 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: 19-006036 type: OTHER domain: Mayo Clinic Institutional Review Board briefTitle: Oropharynx (OPX) Biomarker Trial overallStatus: RECRUITING date: 2019-11-15 date: 2024-12-15 date: 2025-12-15 date: 2024-04-10 date: 2024-04-10 name: Mayo Clinic class: OTHER briefSummary: The purpose of this research is to identify a biomarker that is exists when human papillomavirus (HPV) mediated oropharyngeal squamous cell carcinoma is present and does not exist when HPV mediated oropharyngeal squamous cell carcinoma is absent. conditions: Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 conditions: Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 conditions: Metastatic Oropharyngeal Squamous Cell Carcinoma conditions: Oropharyngeal Squamous Cell Carcinoma conditions: Recurrent Oropharyngeal Squamous Cell Carcinoma conditions: Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 conditions: Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8 studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 180 type: ESTIMATED name: Non-Interventional Study measure: Change in biomarkers measure: Oncologic outcomes associated with biomarkers measure: Genetic alterations measure: Immunologic biomarkers for predicting progression free survival sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mayo Clinic in Rochester status: RECRUITING city: Rochester state: Minnesota zip: 55905 country: United States name: Clinical Trials Referral Office role: CONTACT phone: 855-776-0015 email: mayocliniccancerstudies@mayo.edu name: Diane Vogen role: CONTACT phone: 507-266-1247 email: Vogen.Diane2@mayo.edu name: Kathryn M. Van Abel, M.D. role: PRINCIPAL_INVESTIGATOR lat: 44.02163 lon: -92.4699 hasResults: False
nctId: NCT06356259 id: IMMUNRX-01 id: 2023-503917-31 type: EUDRACT_NUMBER briefTitle: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics Following Intravenous Administration of IRX-010 in Healthy Participants overallStatus: RECRUITING date: 2023-06-07 date: 2025-01-22 date: 2025-01-22 date: 2024-04-10 date: 2024-04-15 name: ImmunoRx Pharma Inc. class: INDUSTRY briefSummary: The purpose of the study is to evaluate the safety, tolerability and pharmacokinetics with intravenous(IV) administration of IRX-010 in Healthy Participants. conditions: Healthy Participants studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: BASIC_SCIENCE masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 81 type: ESTIMATED name: IRX-010 name: Placebo measure: Number of participants with Serious Adverse Events measure: Number of participants with Treatment-Emergent Adverse Events measure: Pharmacokinetics(PK): Area under Curve(AUC) measure: Pharmacokinetics(PK): Maximum Concentration (Cmax) measure: Pharmacokinetics(PK): Half-Life (t½) sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: ICON status: RECRUITING city: Groningen zip: 9728 country: Netherlands name: Renger Tiessen role: CONTACT name: Renger Tiessen role: PRINCIPAL_INVESTIGATOR lat: 53.21917 lon: 6.56667 hasResults: False