hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06263946 id: WS10337 briefTitle: Essilor® Stellest® Lenses Multicentre European Study (SLOMES) acronym: SLOMES overallStatus: RECRUITING date: 2024-03-22 date: 2026-09-30 date: 2026-12-30 date: 2024-02-16 date: 2024-04-03 name: Essilor International class: INDUSTRY briefSummary: The goal of this post-market clinical follow up Study is to demonstrate the efficacy, safety, acceptability, and quality of life implications of Essilor® Stellest® spectacle lenses in slowing myopia progression in European children and adolescents. Participants will receive Essilor® Stellest® at inclusion visit and will be asked for a full time wear (\>12 hours daily) for 24 months. The primary endpoints are the change in axial length and cycloplegic autorefraction from baseline to 24 months compared to expected change based on axial length and refraction centile positions at baseline. conditions: Myopia studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: multicentre, European, prospective primaryPurpose: TREATMENT masking: NONE count: 150 type: ESTIMATED name: Essilor® Stellest® spectacle lenses measure: Change in cycloplegic axial length measure: Change in cycloplegic autorefraction measure: Change in refraction progression centile measure: Change in cycloplegic axial length measure: Change in cycloplegic autorefraction measure: Change in refraction measure: Change in axial length measure: Change in choroidal thickness measure: Change in refraction measure: Change in axial length vs atropine measure: Change in choroidal thickness measure: Change in Paediatric Refractive Error Profile (PREP-2) score sex: ALL minimumAge: 6 Years maximumAge: 16 Years stdAges: CHILD facility: Hôpital Fondation Adolphe de Rothschild - Ophthalmology Department status: RECRUITING city: Paris zip: 75019 country: France name: Ramin Tadayoni, Professor role: CONTACT email: rtadayoni@for.paris name: Ramin Tadayoni role: PRINCIPAL_INVESTIGATOR lat: 48.85341 lon: 2.3488 facility: Centre for Eye Research Ireland (CERI) - TU DUBLIN status: RECRUITING city: Dublin zip: D07 H6K8 country: Ireland name: Ian Flitcroft, Professor role: CONTACT email: ian.flitcroft@tudublin.ie name: James LOUGHMAN, Professor role: CONTACT phone: +353868589593 email: james.loughman@tudublin.ie name: Ian Flitcroft, Pr. role: PRINCIPAL_INVESTIGATOR name: James Loughman, Pr. role: SUB_INVESTIGATOR lat: 53.33306 lon: -6.24889 facility: Erasmus Medical Center status: NOT_YET_RECRUITING city: Rotterdam zip: 3015 country: Netherlands name: Caroline Klaver, Professor role: CONTACT email: c.c.w.klaver@erasmusmc.nl name: Jan Roelof Polling role: CONTACT phone: 010-7040704 email: j.polling@erasmusmc.nl name: Caroline Klaver role: PRINCIPAL_INVESTIGATOR name: Jan Roelof Polling role: SUB_INVESTIGATOR lat: 51.9225 lon: 4.47917 hasResults: False
nctId: NCT06263933 id: 2023-A01804-41 briefTitle: Effect of Experience Sharing and Mutual Assistance on Insight and Recovery During the First Psychotic Episode acronym: DIPEM overallStatus: RECRUITING date: 2023-11-13 date: 2024-11-13 date: 2025-11-13 date: 2024-02-16 date: 2024-02-16 name: Centre hospitalier de Ville-Evrard, France class: OTHER briefSummary: Controlled, prospective, qualitative and quantitative trial. The goal of this trial is to evaluate the mutual assistance early intervention device efficacy and its impact on insight and personal recovery of participants living with a first psychotic episode. This intervention lasts 5 days with 1 session per day of 1 hour 30 minutes. Three evaluations, before the intervention, after intervention and 1 month after the hospitalization's end. conditions: Psychotic Episode studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A control group and a intervention group primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 50 type: ESTIMATED name: Insight Scale name: Semi-directional interviews name: routine care name: session of mutual assistance with a mediator psychologist measure: The level of the increasing of The INSIGHT scale measure: The increase of Recovery Scale measure: The semi-structured interview sex: ALL minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: Etablissement Public de Santé de Ville-Evrard status: RECRUITING city: Neuilly-sur-Marne zip: 93330 country: France name: Rusheenthira Thavaseelan role: CONTACT phone: 0143093232 phoneExt: 033 email: r.thavaseelan@epsve.fr name: Dominique Januel role: CONTACT phone: 0143093232 phoneExt: 033 email: d.januel@epsve.fr name: Dominique Januel, Pr role: PRINCIPAL_INVESTIGATOR name: Ilona Arcomano, PhD role: SUB_INVESTIGATOR lat: 48.85373 lon: 2.54903 hasResults: False
nctId: NCT06263920 id: 288703 briefTitle: Neurofrailty: A Study of Late-onset Epilepsy and Its Associations overallStatus: RECRUITING date: 2022-05-05 date: 2027-01-12 date: 2027-01-12 date: 2024-02-16 date: 2024-02-16 name: Lancashire Teaching Hospitals NHS Foundation Trust class: OTHER briefSummary: We don't know a great deal about why some people develop seizures in adulthood, but some researchers think that it might tell us something about the brain. A small number of people with first seizure in adulthood go on to experience problems like stroke or dementia later in life. However, stroke and dementia are common diseases, so we don't know whether there is a real association between these conditions. When people develop their first seizure in adult life, this is sometimes called Late-Onset Epilepsy. Through the NeuroFrailty study, we will observe 'brain health' over the years following the onset of a seizure, and I hope that it might give us more information about people with these kinds of seizures.
Over the following years, we will look at how things change: for example whether there are changes in memory, new diagnoses, medication changes and how lifestyle has changed. Because there is so little research in this area, it is very difficult to predict what might happen. For example, some people can experience worse memory because of medication side effects; on the other hand, good seizure control following a diagnosis can sometimes lead to improved memory. Over years, it may become clear that some diseases are more likely in people with late-onset epilepsy than in people without such a diagnosis. You will receive a yearly newsletter to keep you updated on everything we learn about late-onset epilepsy.
Neurofrailty = A condition whereby a person is at risk of stroke or dementia. conditions: Late Onset Epilepsy conditions: Stroke conditions: Dementia studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 360 type: ESTIMATED measure: At the time of onset, do people with late-onset epilepsy have higher prevalence of cerebrovascular disease risk factors compared to a control population? measure: Quality of Life - how of chronic illness is mediated measure: What is the absolute and relative incidence of stroke and dementia in people after the onset of LOE compared to the background population? measure: Which anti-epileptic drugs are used in current practice in LOE, and how are they tolerated? sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Lancashire Teaching Hospitals NHS status: RECRUITING city: Preston state: Lancashire zip: PR2 9HT country: United Kingdom name: Kina Bennett role: CONTACT phone: (+44) 01772 522031 email: kina.bennett@lthtr.nhs.uk name: Research Access role: CONTACT email: research.access@lthtr.nhs.uk name: Jasmine Wall role: PRINCIPAL_INVESTIGATOR lat: 53.76282 lon: -2.70452 hasResults: False
nctId: NCT06263907 id: stellate ganglion block briefTitle: Stellate Ganglion Block for Prevention of Post Mastectomy Depression acronym: SGB overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-12-31 date: 2025-04-30 date: 2024-02-16 date: 2024-02-28 name: Mansoura University class: OTHER briefSummary: Complications after mastectomy include chronic pain and depression. conditions: Mastectomy conditions: Pain, Acute conditions: Pain, Chronic studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Patients will be randomization into two equal groups using computer-generated random numbers prior to surgery of 70 each; Group S: will receive ipsilateral stellate gangalion block and Group C: will receive no block. primaryPurpose: PREVENTION masking: DOUBLE maskingDescription: The anesthesiologist, who will be responsible for opening the envelope and do the block or not according to the group besides, evaluation of its success and covering the skin over the site of ipsilateral stellate gangalion with sterile dressing in both groups, will not be involved in data collection. whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 140 type: ESTIMATED name: Stellate gangalion block measure: incidence of postmastectomy depression measure: incidence of postmastectomy depression measure: the need for postoperative antidepressant measure: acute postoperative pain at the incision site (breast and the axilla) measure: chronic postmastectomy pain at the incision site measure: incidence of nausea and vomiting measure: Functional pain in the ipsilateral shoulder measure: Any complications related to stellate ganglion injection sex: FEMALE minimumAge: 21 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06263894 id: MarmaraU-Ebe-ZDY-01 briefTitle: Alexander Technique on Labor Pain and Anxiety overallStatus: RECRUITING date: 2024-02-05 date: 2024-06-01 date: 2024-07-02 date: 2024-02-16 date: 2024-02-20 name: Marmara University class: OTHER name: The Scientific and Technological Research Council of Turkey briefSummary: This study will examine the effect of the Alexander Technique on labor pain and anxiety during labor. This study is designed as a randomized controlled experimental study. The population of the study consists of primiparous pregnant women who applied to Istanbul Provincial Health Directorate Başakşehir Çam and Sakura City Hospital, D-Block Maternity Hospital between November 2023 and May 2024. In calculating the sample size, G\*Power (3.1.9.6) program was used to calculate the sample size with an error of 0.05, effect level of 0.5, power of 95%, and the required sample size for 2 groups was calculated as 34 people for each group with a total of 68 people. conditions: Labor Pain conditions: Anxiety studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: One experimental group and one conventional (control) group primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE maskingDescription: In order to reduce selection bias in determining the experimental and control groups, a computer-assisted randomization program (https://www.randomizer.org) will be used for pregnant women who meet the inclusion criteria. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 68 type: ESTIMATED name: Experimental group measure: Decreasing labor pain measure: Decreasing anxiety sex: FEMALE minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: Başakşehir Çam and Sakura City Hospital status: RECRUITING city: Istanbul country: Turkey name: Ayşen Özgür role: CONTACT phone: +905393806296 email: aysenozgurr@gmail.com lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06263868 id: 69HCL23_1090 id: 2023-A02313-42 type: OTHER domain: ID-RCB briefTitle: First Observatory of Precocious Puberty. acronym: PAPPEL overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2028-03-01 date: 2028-03-01 date: 2024-02-16 date: 2024-02-20 name: Hospices Civils de Lyon class: OTHER briefSummary: The age of puberty has fluctuated throughout history. Recent data shows an increase in the age of onset of puberty signs, in the United States but also in Europe. A recent Public Health France study published in 2018 reports an increase in the incidence of precocious puberty with geographical heterogeneity. The consequences of these appearances include the early onset of menarche, short adult height and the psychological impact.
nctId: NCT06263855 id: 24-000352 briefTitle: Effect of Large Language Model in Assisting Discharge Summary Notes Writing for Hospitalized Patients overallStatus: ENROLLING_BY_INVITATION date: 2024-07-01 date: 2024-12-31 date: 2025-04-01 date: 2024-02-16 date: 2024-04-05 name: Mayo Clinic class: OTHER briefSummary: This pilot study aims to assess the feasibility of carrying out a full-scale pragmatic, cluster-randomized controlled trial which will investigate whether discharge summary writing assisted by a large language model (LLM), called CURE (Checker for Unvalidated Response Errors), improves care delivery without adversely impacting patient outcomes. conditions: Large Language Model studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 1015 type: ESTIMATED name: CURE measure: Rate of patient accrual sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mayo Clinic city: Rochester state: Minnesota zip: 55905 country: United States lat: 44.02163 lon: -92.4699 hasResults: False
nctId: NCT06263842 id: KFSIRB200-132 briefTitle: Elamrousy Novel Approach of Socket Shield Technique overallStatus: RECRUITING date: 2024-02-10 date: 2025-02-10 date: 2025-02-20 date: 2024-02-16 date: 2024-03-12 name: Kafrelsheikh University class: OTHER briefSummary: The current trial aim was to evaluate clinically and radiographically the changes around dental implants inserted immediately in maxillary anterior esthetic zone using a novel combination of autogenous whole tooth graft (AWTG) with socket shield approach (SSA) and compared this approach to socket shield technique with xenograft.
The present study included 63 patients, aged 20 to 45, with teeth that needed to be extracted. After Kafrelsheikh University research ethics committee approval, patients were randomized into 3 groups: group I patients underwent immediate implantation using socket shield protocol, while group II patients underwent the same procedure, but the shield/fixture jumping gap was grafted by xenograft. finally group III was grafted by AWTG that was created using the decoronated crown and the extracted palatal portion of the tooth; and then placed in the peri-implant gap defect. conditions: Implant Complication studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The present study included 63 participants, aged 20 to 45, with teeth that needed to be extracted. After Kafrelsheikh University research ethics committee approval, patients were randomized into 3 groups: group I patients underwent immediate implantation using SSA protocol without grafting, while group II was grafted by xenograft, but group II was grafted with AWTG was created using the decoronated crown and the extracted palatal portion of the tooth; and then placed in the peri-implant gap defect. Clinically, pink aesthetic score (PES), midfacial mucosal alterations (MFMA), stability quotient of dental implants (SQDI) were observed at baseline, six and twelve months after implantation. Moreover, baseline, 6- and 12-months alterations of radiographic horizontal buccolingual ridge width (HBLRW), facial marginal bone level (FMBL), peri-implant Density of bone (PIDB) and peri-implant vertical bone defect depth (PIVBDD) changes were assessed using cone beam computed tomography (CBCT). primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: neither participant nor the outcome assessor know the group distribution whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 63 type: ESTIMATED name: modified Elamrousy approach for socket shield technique name: conventional socket shield name: combined socket shild with xenograft measure: Stability Quotient of dental implant (SQDI) measure: pink esthetic score (PES) measure: Midfacial Mucosal Alterations measure: facial marginal bone level (FMBL) sex: ALL minimumAge: 25 Years maximumAge: 40 Years stdAges: ADULT facility: Walid Elamrousy status: RECRUITING city: Kafr Ash Shaykh zip: 76130 country: Egypt name: walid elamrousy, phd role: CONTACT phone: +201005724781 email: Waled_Hammed@den.kfs.edu.eg name: mostafa fayed, bachelor role: CONTACT phone: +201063376252 lat: 31.11174 lon: 30.93991 hasResults: False
nctId: NCT06263829 id: 2023-1580 briefTitle: HCV Tappt Adherence Study overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2025-01-01 date: 2025-07-01 date: 2024-02-16 date: 2024-02-16 name: University of Illinois at Chicago class: OTHER name: Synchronyx name: American Society of Health-System Pharmacists briefSummary: The goal of this non-inferiority clinical trial is to evaluate the efficacy of Tappt, a novel digital medication companion solution, among individuals with hepatitis C virus (HCV) who are starting a daily oral medication regimen following standard of care in a clinical pharmacy setting.
Upon study completion, a retrospective matched control will be established for the intervention group. Historic data for the matched control's adherence, treatment completion, SVR assessment, and SVR rates will be compared to the intervention arm. conditions: Hepatitis C studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 30 type: ESTIMATED name: Use of Tappt App measure: Medication adherence sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06263816 id: CARVECIR briefTitle: Effect of Long-term Carvedilol to Prevent Decompensation or Death in Patients With Asymptomatic Child-Pugh A5 to B8 Cirrhosis and Clinically Significant Portal Hypertension: a Multicenter Double-blind Randomized Control Trial acronym: CARVECIR overallStatus: NOT_YET_RECRUITING date: 2024-11-15 date: 2029-10-15 date: 2030-06-15 date: 2024-02-16 date: 2024-02-20 name: University Hospital, Tours class: OTHER name: Centre Hospitalier Universitaire Amiens Picardie name: Centre Hospitalier Universitaire Angers name: Assistance Publique Hopitaux Paris BEAUJON name: Centre Hospitalier Universitaire Caen name: Centre Hospitalier intercommunal de Créteil name: Hospices Civils de Lyon name: Centre Hospitalier Universitaire Grenoble name: Centre Hospitalier Universitaire Haut Lévêque name: Centre Hospitalier Régional Universitaire Lille name: Centre Hospitalier Universitaire Jean Minjoz name: Assistance Publique Hopitaux Paris AVICENNE name: Centre Hospitalier Universitaire Clermont Ferrand name: Assistance Publique Hopitaux Paris LA PITIE SALPETRIERE name: Centre Hospitalier Universitaire Pontchaillou name: Assistance Publique Hopitaux Paris ST ANTOINE name: Assistance Publique Hopitaux Paris PAUL BROUSSE name: University Hospital, Montpellier name: Assistance Publique Hopitaux Paris HENRI MONDOR name: Centre Hospitaliser Départemental de Vendée name: Nantes University Hospital name: Centre Hospitalier Universitaire Dijon name: CHU de Reims name: Hôpitaux Universitaires de Strasbourg name: University Hospital, Toulouse briefSummary: Decompensation of cirrhosis is a turning point in cirrhosis course, as associated with a marked decrease in life expectancy. Thus, prevention of decompensation is crucial.
nctId: NCT06263803 id: Karataymusic briefTitle: The Effect of Listening to Music on Chronic Low Back Pain overallStatus: RECRUITING date: 2024-02-01 date: 2024-04-01 date: 2024-04-15 date: 2024-02-16 date: 2024-02-16 name: KTO Karatay University class: OTHER briefSummary: The effects of passive music listening on pain, anxiety and quality of life in patients with chronic low back pain in addition to physical therapy will be examined. conditions: Pain, Chronic studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE maskingDescription: single whoMasked: PARTICIPANT count: 60 type: ESTIMATED name: Music listening, classic physical therapy measure: Beck anxiety inventory measure: Visual Analogue Scale measure: Short From-36 sex: ALL minimumAge: 30 Years maximumAge: 50 Years stdAges: ADULT facility: Mustafa Savaş Torlak status: RECRUITING city: Karatay state: Eyalet/Yerleşke zip: 42000 country: Turkey name: Mustafa S Torlak role: CONTACT phone: +905373660138 email: mustafa.savas.torlak@karatay.edu.tr lat: 37.86726 lon: 32.52863 hasResults: False
nctId: NCT06263790 id: NEOUNIPD1(2024) briefTitle: Intubating Laryngeal Mask vs Direct Laryngoscopy: a Crossover Randomized Controlled Preterm Manikin Trial overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-03 date: 2024-03 date: 2024-02-16 date: 2024-02-16 name: University Hospital Padova class: OTHER briefSummary: The study aims to compare the success and time of intubation through an intubating laryngeal mask vs. direct laryngoscopy in a manikin simulating a term infant. In addition, we will assess the operator's opinion on the procedure.
This is an unblinded, randomized, controlled, crossover (AB/BA) pilot trial of intubation procedure through intubating laryngeal mask vs direct laryngoscopy in a manikin simulating a term newborn. conditions: Neonatal Disease conditions: Intubation; Difficult or Failed studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: NONE count: 50 type: ESTIMATED name: Intubating laryngeal mask name: Direct laryngoscopy measure: Success at the first attempt measure: Time of device positioning measure: Participant's opinion on difficulty of the procedure sex: ALL minimumAge: 25 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06263777 id: P.T.REC/012/004142 briefTitle: Early Detection of Children With Developmental Disabilities in Assiut Governorate overallStatus: COMPLETED date: 2021-01-01 date: 2021-03-15 date: 2021-09-30 date: 2024-02-16 date: 2024-02-16 name: Beni-Suef University class: OTHER briefSummary: The study aimed to determine the effectiveness of a designed training program for nurses toward early detection of developmental disabilities among children (0-3 years). conditions: Developmental Disability conditions: Development Delay conditions: Motor Delay conditions: Down Syndrome conditions: Autism Spectrum Disorder studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 21 type: ACTUAL name: Nurses training program on early detection of disability measure: Questionnaire of Screening and referral knowledge measure: Questionnaire of Disability Perception measure: questionnaire about Monitoring Practices measure: Follow up sex: FEMALE stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Tayseer Saber Abdeldayem city: Banī Suwayf state: Beni-Suef zip: 62521 country: Egypt lat: 29.07441 lon: 31.09785 hasResults: False