hackint0sh/New-Dataset huggingface dataset:
The aim of the study is to assess whether the joint use of Nutrow-Feedim improves the achievement of nutritional objectives in ICU patients prior to oral intake by reducing the discrepancy between prescribed and delivered calories and protein. conditions: Nutritional Support studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Usual use of standard clinical and biological information related to nutritional support as available through the ICU electronic health record (i.e. without any calculated information on recommended, prescribed, or received calories and protein, only information on prescribed products and volumes as collected by and presented in the ICU EHR) In this arm, participants, investigators, and healthcare professionals will be blinded to real-time enteral feed volumes that will be collected by the Feedim medical device and transmitted to the electronic study case report form. primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 144 type: ESTIMATED name: Nutritional support prescription and delivery monitoring feedback name: Usual care measure: Mean total daily calories delivered/prescribed ratio (percent) measure: Mean total daily protein delivered/prescribed ratio (%) measure: Mean total daily calories delivered/recommended ratio (percent) measure: Mean total daily protein delivered/recommended ratio (percent) measure: Nutritional support duration (days) measure: Time to initiation of nutritional support (days) measure: Weight (Kg) measure: Day 28 mortality rate measure: ICU length-of-stay (days) measure: Days on ventilator (days) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University Hospital Lille status: RECRUITING city: Lille zip: 59037 country: France name: Eric KIPNIS, MD, PhD role: CONTACT phone: +33 (0)3 20 44 59 62 email: eric.kipnis@chu-lille.fr lat: 50.63297 lon: 3.05858 hasResults: False
nctId: NCT06342882 id: GO 19/833- A briefTitle: Dysphagia Severity and Functional Independence Level overallStatus: COMPLETED date: 2020-01-01 date: 2024-01-01 date: 2024-02-01 date: 2024-04-02 date: 2024-04-02 name: Atılım University class: OTHER briefSummary: Functional independence is the ability of a person to perform daily life activities safely without any restriction, as much as possible. The functional independence depends on physical, social, cognitive and psychological abilities of the person. Therefore, full functional independence requires the harmony of all these parameters.
Dysphagia can be seen in more than 50% of neurological patients, and it is called neurogenic dysphagia. Muscle weakness, tonus changes, sensory loss and coordination problems occur in these patients. Pain and fatigue are also frequently observe. These patients have problems with fine and gross motor movements, and thereby mobility and transfer activities become difficult. Life-threatening complications such as pulmonary problems, malnutrition and dehydration accompany when patients have dysphagia. Both neurological and dysphagia-related problems negatively affect the physical, psychological, emotional and cognitive functions of patients. Neurological patients with dysphagia may have more serious clinical situations due to more affected vital functions such as pulmonary functions and feeding.
Dysphagia-induced malnutrition adversely affects many systems, including the musculoskeletal system. In a study conducted in the elderly with dysphagia, atrophy in the total muscle mass and swallowing muscles, and increase in intramuscular adipose tissue were reported as a result of malnutrition. Decreases in the muscle mass may negatively affect the functional independence of patients with dysphagia. Other studies in geriatric population have shown that swallowing function is associated with hand grip strength and quadriceps muscle strength, which are indicators of functional independence in activities of daily living (ADL). These studies also suggest that dysphagia may be associated with functional independence in geriatric group. Therefore, functional independence may also reduce in patients with neurogenic dysphagia. However, there is no study investigating the relationship between dysphagia severity and the functional independence levels in patients with neurological diseases. Therefore, the investigators aimed to investigate the relationship between dysphagia severity and functional independence level in patients with neurological diseases. conditions: Dysphagia conditions: Neurologic Disorder studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 30 type: ACTUAL name: dysphagia assessment name: functional independence level measure: dysphagia severity measure: functional independence sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Atılım Uiveristy city: Ankara state: Incek zip: 06830 country: Turkey lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06342869 id: 690 briefTitle: Comparison of the Effects of Lidocaine and Articaine Used for Buccal Infiltration and Supplemental Palatinal Infiltration Anesthesia in Teeth With Irreversible Pulpitis overallStatus: COMPLETED date: 2022-04-01 date: 2022-10-01 date: 2022-12-01 date: 2024-04-02 date: 2024-04-02 name: Akdeniz University class: OTHER briefSummary: Objective: The aim of this study was to compare the effects of articaine or lidocaine in buccal infiltration or palatal infiltration in addition to buccal infiltration in maxillary first or second molars with irreversible pulpitis.
Method: Among the patients who applied to Akdeniz University Faculty of Dentistry Endodontic Clinic for the treatment of maxillary molars with irreversible pulpitis, 80 volunteers who met the criteria were included in the study. Eighty patients were divided into 4 groups (n = 20). 1. group buccal infiltration with 4% articaine containing 1:100,000 epinephrine, 2. group buccal infiltration with 2% lidocaine containing 80,000 epinephrine, 3. group buccal and palatinal infiltration with 4% articaine containing 1:100,000 epinephrine, 4.group buccal and palatinal infiltration with 2% lidocaine containing 80.000 epinephrine. Pain during the endodontic procedure was determined and recorded according to the Heft Parker visual analog scale. conditions: Fist and Second Molars With ırreversible Pulpitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 80 type: ACTUAL name: Anesthesia measure: Assessment of complementary palatinal anesthesia with VAS sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Akdeniz University city: Antalya zip: 07070 country: Turkey lat: 36.90812 lon: 30.69556 hasResults: False
nctId: NCT06342856 id: idiopathic infertility briefTitle: Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia acronym: infertility overallStatus: RECRUITING date: 2023-06-15 date: 2024-06-01 date: 2024-07-01 date: 2024-04-02 date: 2024-04-02 name: Ain Shams University class: OTHER briefSummary: Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia conditions: Infertility Unexplained conditions: Oligospermia studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: NONE count: 120 type: ESTIMATED name: co enzyme Q10 , L- Carnitine measure: Changes in Semen analysis parameters compared to baseline measure: Serum hormone levels ([FSH], [LH], testosterone, and prolactin) levels compared to baseline and Cost analysis sex: MALE stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Ain Shams University status: RECRUITING city: Cairo zip: 002 country: Egypt name: ahmed ma maher, lecturer role: CONTACT phone: 01013340534 email: drwaleedabdelhamid@gmail.com lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06342843 id: SPLAsH id: NL81395.075.22 type: OTHER domain: CCMO briefTitle: Direct Superior Approach Versus PosteroLateral Approach in Total Hip Arthroplasty (SPLAsH) acronym: SPLAsH overallStatus: RECRUITING date: 2024-02-13 date: 2026-08-30 date: 2026-11-30 date: 2024-04-02 date: 2024-04-02 name: Isala class: OTHER briefSummary: This study will compare postoperative pain, health related quality of life (HRQoL), function, rehabilitation, urinary incontinence, muscle atrophy and component positioning in total hip arthroplasty (THA) using the posterolateral approach (PLA) or the direct superior approach (DSA). In addition, the CT images will be used to validate a new metal artefact reduction technique. conditions: Osteoarthritis, Hip studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: multicenter, prospective, double blinded, randomized controlled intervention study primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 211 type: ESTIMATED name: Total Hip Arthroplasty measure: Hip disability and Osteoarthritis Outcome Score - Physical Function Short Form measure: Numeric Rating Scale (NRS) measure: Short Form-12 (SF-12) measure: Hip disability and Osteoarthritis Outcome Score (HOOS) measure: Euro Quality of Life (EQ-5D) measure: Global Rating of Change scale measure: Timed Up and Go test (TUG test) measure: 40 meter self-paced walk test for hip osteoarthritis measure: Stair climb test measure: Step count application on iPhone measure: Muscle atrophy by using Computer Tomography (CT) scanner measure: Computer Tomography (CT) image with orthopedic metal artefact reduction (O-MAR) measure: Postoperative cup position on Computer Tomography (CT) image measure: Comparing definite cup position with preoperative planned cup position measure: Comparing definite component position with surgeon's perioperative estimation of component position measure: overall image quality measure: image diagnostic confidence measure: metal artifacts on images measure: Incontinence Severity Index (ISI) measure: Urinary Distress Inventory, Short Form (UDI-6) measure: Patient Global Impression of Severity (PGIS) measure: Incontinence Impact Questionnaire Short Form (IIQ-7) measure: Incontinence after Total Hip Arthroplasty sex: ALL minimumAge: 18 Years maximumAge: 99 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Amphia status: NOT_YET_RECRUITING city: Breda state: Brabant zip: 4818CK country: Netherlands name: Stefan BT Bolder, MD role: CONTACT lat: 51.58656 lon: 4.77596 facility: Medisch Centrum Leeuwarden status: NOT_YET_RECRUITING city: Leeuwarden state: Friesland zip: 8934AD country: Netherlands name: Wierd Zijlstra, MD/PhD role: CONTACT lat: 53.20139 lon: 5.80859 facility: Isala status: RECRUITING city: Zwolle state: Overijssel zip: 8000 GK country: Netherlands name: Diederik de Boer, MSc. role: CONTACT phone: 00316248117 email: die.de.boer@isala.nl name: Roelina Munnik, PhD role: CONTACT phone: 00316245375 email: r.munnik@isala.nl name: Harmen Ettema, MD/PhD role: PRINCIPAL_INVESTIGATOR lat: 52.5125 lon: 6.09444 hasResults: False
nctId: NCT06342830 id: End 20-05 P briefTitle: Comparing the Effect of Different Intracanal Dressing on Failed Root Canal Treated Cases on Periapical Healing overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-12 date: 2025-05 date: 2024-04-02 date: 2024-04-08 name: Ain Shams University class: OTHER briefSummary: The goal of this clinical trial is to compare the effects of different intracanal medication between endodontic retreatment visits in previously failed root canal treatment patients (single root canal anteriors or premolars teeth). The main question it aims to answer are:
* calcium hydroxide Paste as control group in between the endodontic retreatment visits to see if these medicaments work well on periapical lesion healing this outcome measured by Cone beam CT at base and after 6 months follow up periods conditions: Periapical Disease studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 80 type: ESTIMATED name: nanocurcumin gel name: Curcumin Gel name: Ciprofloxacin 500 mg +ibuprofen 400mg name: Metapaste [calcium hydroxide paste (control group)] measure: healing of periapical lesion measure: antibacterial effect (CFU) measure: Interappointment Pain sex: ALL minimumAge: 20 Years maximumAge: 60 Years stdAges: ADULT facility: faculty of dentistry, Ain shams university city: Cairo zip: 11512 country: Egypt name: Rawda Baghdady role: CONTACT phone: 01142361074 email: RawdaBaghdady@dent.asu.edu.eg name: sarah H Fahmy role: CONTACT phone: 01005267999 name: Rawda M Baghdady, PHD student role: PRINCIPAL_INVESTIGATOR lat: 30.06263 lon: 31.24967 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2020-09-20 uploadDate: 2024-03-01T05:02 filename: Prot_SAP_000.pdf size: 719008 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2020-09-20 uploadDate: 2024-03-01T05:04 filename: ICF_001.pdf size: 284949 hasResults: False
nctId: NCT06342817 id: UFFS briefTitle: Effects of Meditation on Sleep Quality of Medical Students overallStatus: RECRUITING date: 2023-10-18 date: 2024-06-30 date: 2024-06-30 date: 2024-04-02 date: 2024-04-02 name: Universidade Federal da Fronteira Sul class: OTHER briefSummary: The objective of the study is to evaluate the effect of an 8-week online mindfulness-based meditation program on quality sleep status of undergraduate students medicine in the city of Passo Fundo/RS and Chapecó/SC In addition to sleep quality, secondary outcomes such as mindfulness, symptoms of depression, stress, anxiety and burnout will also be assessed conditions: Sleep Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Those students interested in participating in the study will leave their contact details (telephone and email) to the research coordinator, to whom it will be sent an online questionnaire containing the inclusion and exclusion criteria, and the free consent form through the Google forms platform. Collection instruments will only be made available after fulfilling the inclusion criteria and absence of exclusion criteria and agreement with the consent form. Responders will be randomly randomized 1:1 and subsequently communicated whether they will participate in the intervention group or the control group. primaryPurpose: SUPPORTIVE_CARE masking: NONE maskingDescription: Responders will be randomly randomized 1:1 and subsequently communicated whether they will participate in the intervention group or the control group. count: 136 type: ESTIMATED name: online mindfulness based meditation program measure: Change in the quality of sleep of medical students on weeks 5, 9 and 17 by the PSQI and ESE measure: Change in the awareness of medical students on weeks 5, 9 and 17 by the MAAS measure: Change in the depression, anxiety and stress symptoms of medical students on weeks 5, 9 and 17 by the DASS-21 measure: Change in the burnout symptoms of medical students on weeks 5, 9 and 17 by CBI-S sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Universidade Federal Da Fronteira Sul status: RECRUITING city: Passo Fundo state: RS zip: 99010200 country: Brazil name: Tiago T Simon, MD role: CONTACT phone: +5554991843384 email: tiago.teixeira@uffs.edu.br lat: -28.26278 lon: -52.40667 hasResults: False
nctId: NCT06342804 id: GIB-01-02-2023 briefTitle: Food Effect on the Bioavailability of 4-MUST, Tablets, 128 mg overallStatus: RECRUITING date: 2024-03-19 date: 2024-12-31 date: 2024-12-31 date: 2024-04-02 date: 2024-04-02 name: Valenta Pharm JSC class: INDUSTRY briefSummary: Primary objective of the study: evaluation of the effect of food intake on the bioavailability of 4-MUST, tablets, 128 mg (Valenta Pharm JSC) after a single oral administration on an empty stomach and after a meal, at a dose of 256 mg (two tablets).
Additional aim of the study: evaluation of pharmacokinetic parameters, safety and tolerability of 4-MUST, tablets, 128 mg (Valenta Pharm JSC) in healthy volunteers after a single oral administration on an empty stomach and after a meal, at a dose of 256 mg (two tablets). conditions: Cholecystitis studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: OTHER masking: NONE count: 24 type: ESTIMATED name: 4-MUST, 2 tablets, fasted name: 4-MUST, 2 tablets, after meals measure: Pharmacokinetics - Cmax measure: Pharmacokinetics - tmax measure: Pharmacokinetics - AUC0-t measure: Pharmacokinetics - AUC0-inf measure: Pharmacokinetics - AUC ratio measure: Pharmacokinetics - t1/2 measure: Pharmacokinetics - kel measure: Pharmacokinetics - MRT measure: Pharmacokinetics - Vd measure: Pharmacokinetics - Cmax/AUC0-t measure: Pharmacokinetics - f' measure: Pharmacokinetics - f'' measure: Bioavailability - ratio of Cmax measure: Bioavailability - ratio of AUC0-t measure: Bioavailability - ratio of AUC0-inf measure: Adverse event type measure: Adverse event frequency measure: Adverse event severety measure: Drop-outs associated with adverse events sex: ALL minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Federal Budgetary Institution of Science "North-Western Scientific Center for Hygiene and Public Health" status: RECRUITING city: Saint Petersburg zip: 191036 country: Russian Federation name: Elena S Shalukho, MD role: CONTACT phone: +7 (903) 099 57 86 email: elena.shalukho@yandex.ru lat: 59.93863 lon: 30.31413 hasResults: False
nctId: NCT06342791 id: 004349 briefTitle: Effect of Laser Acupuncture on Menstrual Back Pain overallStatus: RECRUITING date: 2024-02-20 date: 2024-05-20 date: 2024-06-20 date: 2024-04-02 date: 2024-04-02 name: Cairo University class: OTHER briefSummary: effect of laser acupuncture on menstrual back pain conditions: Laser Acupuncture conditions: Low Back Pain conditions: Menstruation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: two groups primaryPurpose: TREATMENT masking: SINGLE maskingDescription: laser acupuncture whoMasked: PARTICIPANT count: 32 type: ESTIMATED name: laser acupuncture measure: back Pain intensity during menstruation measure: pain threshold measure: Ability to perform daily activities measure: back Pain intensity during menstruation measure: pain threshold measure: Ability to perform daily activities sex: FEMALE minimumAge: 20 Years maximumAge: 30 Years stdAges: ADULT facility: Faculty of physical therapy cairo university status: RECRUITING city: Cairo zip: 37617692 country: Egypt name: Mai Ali Galal El sayed role: CONTACT phone: 01152457470 email: Princessmai828@gmail.com lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06342778 id: DIP-05-02-2023 briefTitle: Pharmacokinetics and Bioequivalence of Doxylamine+Pyridoxine and Diclectin overallStatus: RECRUITING date: 2024-02-27 date: 2024-12-31 date: 2024-12-31 date: 2024-04-02 date: 2024-04-02 name: Valenta Pharm JSC class: INDUSTRY briefSummary: Comparative study of pharmacokinetics and bioequivalence of the study drug Doxylamine + Pyridoxine, enteric-soluble, film-coated tablets, 10 mg + 10 mg (Valenta Pharm JSC, Russia), and reference drug Diclectin, delayed-release tablets, 10 mg + 10 mg (registration certificate holder - Tzamal Bio-Pharma, Israel, manufacturer - Duchesnay Inc, Canada) in healthy volunteers after meals conditions: Nausea studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: OTHER masking: NONE count: 28 type: ESTIMATED name: Doxylamine + Pyridoxine name: Diclectin measure: Pharmacokinetics - Cmax measure: Pharmacokinetics - tmax measure: Pharmacokinetics - AUC0-t measure: Pharmacokinetics - AUC0-inf measure: Pharmacokinetics - AUCextr measure: Pharmacokinetics - t1/2 measure: Pharmacokinetics - kel measure: Pharmacokinetics - MRT measure: Bioequivalence - ratio of Cmax measure: Bioequivalence - ratio of AUC0-t measure: Bioequivalence - ratio of AUC0-inf measure: Adverse event type measure: Adverse event frequency measure: Adverse event severety sex: FEMALE minimumAge: 18 Years maximumAge: 49 Years stdAges: ADULT facility: GBOU VPO "Yaroslavl State Medical University" of Ministry of Health of Russian Federation status: RECRUITING city: Yaroslavl zip: 150000 country: Russian Federation name: Sergey M Noskov, Prof. role: CONTACT phone: +7-4852-242332 email: Noskov-SM@mail.ru lat: 57.62987 lon: 39.87368 hasResults: False
nctId: NCT06342765 id: SV009 briefTitle: Safety and Performance of the SpineVision Posterior Fixation Systems in Thoracolumbar Spinal Treatment acronym: FixedD3 overallStatus: RECRUITING date: 2022-09-22 date: 2028-05-30 date: 2028-05-30 date: 2024-04-02 date: 2024-04-03 name: SpineVision class: INDUSTRY name: Slb Pharma briefSummary: The goal of this observational study is to confirm the safety and performance of the three (3) Spinevision posterior fixations systems Lumis®, Plus® and Ulis® , in the treatment of patient suffering from thoracolumbar spinal degenerative pathologies, or degenerative disc disease (disease that occurs when the spinal disk break down) associated pathologies.
Part of their standard of care, participants will be questioned on their back and leg pains, their disability and if they have encountered any adverse effects since the Spinevision posterior fixation system implant surgery. Those data will be collected up to twenty four (24) months after the Spinevision posterior fixation system implant surgery. conditions: Intervertebral Disc Degeneration studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: OTHER count: 330 type: ESTIMATED name: Pedicle fixation surgery measure: Incidence of serious and non-serious device- and/or procedure-related adverse events measure: Change of the Oswestry Disability Index (ODI) measure: Fusion success measure: Change of the Oswestry Disability Index (ODI) measure: Change of the back and leg Visual Analogue Score (VAS) measure: Incidence of revision surgery at implant site sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: DOSCEA Pôle Rachis status: RECRUITING city: Bayonne zip: 64100 country: France name: Jean Bernard role: CONTACT email: secretariatdoscea@outlook.fr lat: 43.48333 lon: -1.48333 facility: Clinique du dos Bordeaux-Terrefort status: RECRUITING city: Bruges zip: 33520 country: France name: Louis Boissière, Doctor role: CONTACT email: boissierelouis@gmail.com lat: 44.87981 lon: -0.61219 facility: Orthéo Neurochirurgie status: RECRUITING city: Saint-Étienne zip: 42199 country: France name: Benjamin Pommier, Doctor role: CONTACT email: benjamin.pommier@neurochirurgie.fr lat: 45.43389 lon: 4.39 hasResults: False
nctId: NCT06342752 id: 6007 briefTitle: The Role of VOCs, Airway Mucins and Airway Microbiome in Bronchopulmonary Dysplasia acronym: INFANCY overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-09 date: 2027-09 date: 2024-04-02 date: 2024-04-02 name: University Hospital, Antwerp class: OTHER briefSummary: Bronchopulmonary dysplasia (BPD), the most common respiratory complication of extremely preterm birth, significantly impacts healthcare with high morbidity and mortality rates.
Despite the well-established primordial role of inflammation and oxidative stress in the development of BPD, clinical practice does not incorporate the testing for biomarkers associated with the development of BPD. The diagnosis of BPD based on required respiratory support at 36 weeks PML, stresses the need for an early prediction tool which could identify patients with high levels of these biomarkers. This on its turn, could also improve treatment approaches in clinical practice which are currently mostly supportive or non-specific and do not target underlying pathophysiologic pathways.