This is a multi-center prospective observational study conducted in patients with Severe Acquired Brain Injury (sABI) and DoC admitted to 8 European participating centers, with clinical data collection not deviating from routine practice. The study is non-commercial and will have a maximum total duration of 24 months. conditions: Disorders of Consciousness studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 70 type: ESTIMATED measure: Clinical Diagnosis sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Coma Science Group, GIGA-Consciousness, University of Liege city: Liege zip: 4000 country: Belgium name: Olivia Gosseries, PhD role: CONTACT email: ogosseries@uliege.be name: Olivia Gosseries, PhD role: PRINCIPAL_INVESTIGATOR name: Aurore Thibaut, PhD role: SUB_INVESTIGATOR name: Youssra Mezoudi, M.Sc. role: SUB_INVESTIGATOR lat: 50.63373 lon: 5.56749 facility: Therapiezentrum Burgau city: Burgau zip: 89331 country: Germany name: Andreas Bender, MD role: CONTACT email: a.bender@therapiezentrum-burgau.de name: Andreas Bender, MD role: PRINCIPAL_INVESTIGATOR name: Martin Rosenfelder, PhD role: SUB_INVESTIGATOR lat: 48.43159 lon: 10.40989 facility: Dipartimento di Neurologia, LMU Hospital, LMU Munich city: Munich zip: 81377 country: Germany name: Konstantinos Dimitriadis role: CONTACT email: konstantin.dimitriadis@med.unimuenchen.de name: Konstantinos Dimitriadis role: PRINCIPAL_INVESTIGATOR name: Moritz Schmidbauer role: SUB_INVESTIGATOR name: Julia Zibold role: SUB_INVESTIGATOR lat: 48.13743 lon: 11.57549 facility: Polo Specialistico Riabilitativo Fondazione Don Carlo Gnocchi ONLUS city: Sant'Angelo dei Lombardi state: AV zip: 83054 country: Italy name: Anna Estraneo, PhD role: CONTACT phone: 3396418648 phoneExt: 39 email: aestraneo@dongnocchi.it name: Alfonso Magliacano, PhD role: CONTACT phone: 3387389414 phoneExt: 39 email: amagliacano@dongnocchi.it name: Anna Estraneo, MD role: PRINCIPAL_INVESTIGATOR name: Alfonso Magliacano, PhD role: SUB_INVESTIGATOR name: Giovanni Scarano, BS role: SUB_INVESTIGATOR lat: 40.92937 lon: 15.17535 facility: Unità Gravi Cerebrolesioni - Dipartimento Neuroscienze - Azienda Ospedaliera - Universitaria Ferrara city: Ferrara zip: 44124 country: Italy name: Susanna Lavezzi role: CONTACT email: s.lavezzi@ospfe.it name: Susanna Lavezzi role: PRINCIPAL_INVESTIGATOR name: Valentina Bonsangue role: SUB_INVESTIGATOR name: Sofia Straudi role: SUB_INVESTIGATOR lat: 44.83804 lon: 11.62057 facility: IRCCS Fondazione Don Gnocchi ONLUS city: Florence zip: 50143 country: Italy name: Bahia Hakiki, PhD role: CONTACT email: bhakiki@dongnocchi.it name: Bahia Hakiki, PhD role: PRINCIPAL_INVESTIGATOR name: Andrea Mannini, PhD role: SUB_INVESTIGATOR name: Piergiuseppe Liuzzi, PhD role: SUB_INVESTIGATOR lat: 43.77925 lon: 11.24626 facility: IRCCS Santa Maria Nascente Fondazione Don Gnocchi ONLUS city: Milan zip: 20148 country: Italy name: Angela Comanducci, PhD role: CONTACT email: acomanducci@dongnocchi.it name: Angela Comanducci, PhD role: PRINCIPAL_INVESTIGATOR name: Tiziana Atzori role: SUB_INVESTIGATOR name: Chiara-Camilla Derchi role: SUB_INVESTIGATOR lat: 45.46427 lon: 9.18951 facility: Instituto de Rehabilitación Neurológica IRENEA city: Valencia zip: 46007 country: Spain name: Enrique Noé, MD role: CONTACT email: enoe@comv.es name: Enrique Noé, MD role: PRINCIPAL_INVESTIGATOR name: Roberto Llorens, PhD role: SUB_INVESTIGATOR name: Alejandro Galvao, PhD role: SUB_INVESTIGATOR lat: 39.46975 lon: -0.37739 hasResults: False