hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06301204 id: 21.06.2022-E.67046 briefTitle: Effectiveness Of Tranexamic Acıd Application Wıth Different Doses On Bleeding, Edema And Physician Comfort In Orthognathıc Surgery Patients overallStatus: COMPLETED date: 2022-03-01 date: 2023-11-01 date: 2023-11-01 date: 2024-03-08 date: 2024-03-08 name: Bezmialem Vakif University class: OTHER briefSummary: The aim of this clinical study conducted in accordance with the information in the literature is to compare the effects of administering tranexamic acid during orthognathic surgery, at different doses. Specifically, investigators aim to compare the effects of administering 1 ampoule IV (approximately 3 mg/kg) and 2 ampoules IV (approximately 6 mg/kg), and evaluate their impact on intraoperative bleeding (ml), surgical duration (min), postoperative swelling, and intraoperative surgical field evaluation (Fromme Scale), by comparing them with control group (applying no drug administration) patient data. conditions: Tranexamic Acid conditions: Orthognathic Surgery conditions: Edema conditions: Bleeding studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: SINGLE whoMasked: PARTICIPANT count: 60 type: ACTUAL name: Tranexamic acid injection name: Saline measure: intraoperative bleeding during the surgery (ml) measure: postoperative edema calculation for the first 1-3 and 7 day (cm) measure: intraoperative surgical site evaluation (Fromme Scale) measure: Hemoglobin (Hgb) and Hematocrit (Hct) values alteration preoperative and postoperative 2. day sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Bezmialem Vakıf Universty city: Istanbul state: Fatih zip: 34093 country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06301191 id: 133/21-02-2022 briefTitle: The Effect of Semaglutide on Cardiovascular Markers and Liver Function overallStatus: RECRUITING date: 2022-03-01 date: 2023-03-01 date: 2024-05-01 date: 2024-03-08 date: 2024-03-08 name: Attikon Hospital class: OTHER briefSummary: Fifty patients with diabetes mellitus type 2 and non-alcoholic fatty liver disease (NAFLD) will be enrolled in the study.
At baseline, at four and at 12 months will evaluate the endothelial, cardiovascular and liver function. conditions: Diabetes Type 2 studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 50 type: ESTIMATED name: Semaglutide, 1.0 mg/mL name: Dipeptidyl Peptidase 4 inhibitor measure: Comparison of arterial stiffness markers difference among treatment groups measure: Comparison of endothelial glycocalyx thickness difference among treatment groups measure: Comparison of liver stiffness difference among treatment groups sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Attikon University General Hospital status: RECRUITING city: Athens zip: 12462 country: Greece name: Vaia Lambadiari, Professor role: CONTACT phone: 2105831148 email: vlambad@otenet.gr lat: 37.97945 lon: 23.71622 hasResults: False
nctId: NCT06301178 id: 12548 briefTitle: Effect of Vitamin D Injection on Hypertrophic Scars and Keloids overallStatus: RECRUITING date: 2024-02-27 date: 2025-02-20 date: 2026-02-20 date: 2024-03-08 date: 2024-03-21 name: Mostafa Bahaa class: OTHER briefSummary: Scars and keloids cause patients severe morbidity and psychological distress. Hypertrophic scars rise above the skin but stay within the scar boundaries, while keloids expand.
The development of keloids and hypertrophic scars is a consequence of insufficient wound healing. These lesions are distinguished by excessive ECM deposition. Excessive ECM deposition is caused by increased inflammatory and proliferative processes and decreased remodeling activities. These scarring lesions are also linked to genetic and systemic causes conditions: Dermatologic Disease studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 35 type: ESTIMATED name: Cholecalciferol measure: Clinical scoring by Vancouver Scale Score sex: ALL minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: faculty of medicine-Fayoum university status: RECRUITING city: Fayoum zip: 63519 country: Egypt name: Marwa Kamal, PhD role: CONTACT phone: 01021365897 email: mka05@fayou.edu.eg lat: 29.30995 lon: 30.8418 hasResults: False
nctId: NCT06301152 id: E2-22-1905 briefTitle: Lateral Epicondylitis Treatment High Intensive Laser Therapy and Extracorporeal Shock Wave Therapy overallStatus: COMPLETED date: 2022-09-01 date: 2022-10-01 date: 2023-05-30 date: 2024-03-08 date: 2024-03-08 name: Ankara City Hospital Bilkent class: OTHER briefSummary: Objectives: This study aims to evaluate and compare the short-term efficacy of high-intensity laser therapy (HILT) and extra corporeal shock wave therapy(ESWT) on pain, sensitivity, handgrip strength, and functions in the treatment of lateral epicondylitis (LE).
Material and methods: Forty five participants (age range, 18 to 65 years) with unilateral elbow pain were randomized into two groups. HILT group (n = 22) and the ESWT group (n = 23). The HILT and ESWT were administered three times a week for three weeks, and each treatment was combined with exercises. All patients in both groups were evaluated with ultrasonography for common extensor tendon(CET) thickness. A visual analog scale (VAS), Quick Disabilities of the Arm, Shoulder, and Hand (QDASH), and hand grip strength test were used to evaluate the patients before, one, and six weeks after treatment. conditions: Lateral Epicondylitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: two different treatment modalities were applied in two groups primaryPurpose: TREATMENT masking: NONE count: 40 type: ACTUAL name: high intensive laser name: extracorporeal shock wave therapy measure: Visual analog scale measure: Quick Disability Arm, Shoulder and Hand questionary, measure: hand grip strength measure: musculoskeletal ultrasonography sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Emine Esra Bilir city: Ankara state: Çankaya zip: 06800 country: Turkey lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06301139 id: P17-004 briefTitle: Goat Milk Infant Formula Comfort Study overallStatus: COMPLETED date: 2019-05-01 date: 2021-04-01 date: 2024-02-01 date: 2024-03-08 date: 2024-03-08 name: Ausnutria Hyproca B.V. class: INDUSTRY name: HM hospitales briefSummary: In this study, the investigators aim to assess that infants with mild symptoms have significantly less (severe) symptoms after 14 days goat milk-based formula use compared to infants using cow's milk-based formula supplemented with probiotic drops. conditions: Gastrointestinal Diseases conditions: Cow's Milk Intolerance studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: randomized controlled pilot study primaryPurpose: TREATMENT masking: NONE count: 18 type: ACTUAL name: Goat milk-based infant formula name: Cow's milk-based infant formula with probiotic drops measure: Cow's Milk-related Symptoms measure: Cow's Milk-related Symptoms measure: Parental stress measure: Parental quality of life measure: Weight measure: Length measure: Weight-for-age measure: Length-for-age measure: Weight-for-length sex: ALL minimumAge: 6 Weeks maximumAge: 3 Months stdAges: CHILD facility: HM hospitales city: Madrid zip: 28015 country: Spain lat: 40.4165 lon: -3.70256 hasResults: False
nctId: NCT06301126 id: P.T.REC/012/004985 briefTitle: Virtual Reality on Pulmonary Function After Upper Abdominal Surgeries overallStatus: RECRUITING date: 2024-03-01 date: 2025-02-01 date: 2025-03-01 date: 2024-03-08 date: 2024-03-12 name: Cairo University class: OTHER briefSummary: After upper abdomen surgery, respiratory muscle dysfunction is well recognised. After laparotomy and even laparoscopy, maximum static inspiratory and expiratory pressures are lowered, and recovery can take several days. A variety of reasons have been implicated in such respiratory muscle dysfunction, including irritation and inflammation, as well as injuries near the diaphragm, resulting in local mechanical failure, reflex inhibition, and pain. conditions: Abdomen Hernia conditions: Respiratory Complication studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: INVESTIGATOR count: 60 type: ESTIMATED name: Virtual reality name: conventional physical therapy exercise program measure: Forced vital capacity (FVC) measure: Forced expiratory volume in 1 second (FEV1) measure: Peak expiratory flow (PEF) measure: Respiratory muscle strength measure: diaphragmatic mobility measure: Functional capacity sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Faculty of Physical Therapy status: RECRUITING city: Giza zip: 12111 country: Egypt name: Nesma M Allam, PhD role: CONTACT phone: +201281968332 email: dr.nesma2011@yahoo.com lat: 30.00808 lon: 31.21093 hasResults: False
nctId: NCT06301113 id: IRB#: 01202023_torabiDH_CBDloz briefTitle: This Research Study Examines the Effects of Cannabidiol-infused Candy on Reducing the Bacteria Causing Tooth Decay, When Comparing it to a Sugar Free Candy on Adults. overallStatus: COMPLETED date: 2023-01-27 date: 2023-02-11 date: 2023-02-11 date: 2024-03-08 date: 2024-03-08 name: West Coast University class: OTHER briefSummary: The goal of this clinical trial is to compare the effect of CBD candy versus sugar free candy on reducing the number of bacteria causing tooth decay, in adults The main question is to see whether CBD have any effect on reducing the number of Streptococcus mutans, in the oral cavity the main bacteria causing tooth decay.
A sample of saliva will be collected and analyzed in a lab before and after consumption of the candy to see whether either product could reduce the harmful bacteria in the mouth. conditions: Tooth Decay studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: 30 Participants were randomly assigned to groups A (experimental group)and B (Control group). primaryPurpose: BASIC_SCIENCE masking: NONE count: 30 type: ACTUAL name: CBD infused candy name: Sugar free Candy measure: To investigate the impact of CBD-infused lozenges on Streptococcus mutans, by employing quantitative polymerase chain reaction (qPCR) for bacterial analysis. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: West Coast University city: Anaheim state: California zip: 92802 country: United States lat: 33.83529 lon: -117.9145 hasResults: False
nctId: NCT06301100 id: E20230371 briefTitle: Single-center, Prospective Study on the Identification and Delineation of Brain and Lung Tumors and At-Risk Organs, and Functional Testing of Surrounding Tissues Based on Dual-Energy CT overallStatus: RECRUITING date: 2023-04-28 date: 2024-04-28 date: 2024-12-31 date: 2024-03-08 date: 2024-03-08 name: Tianjin Medical University Cancer Institute and Hospital class: OTHER briefSummary: This study explored the feasibility of dual-energy CT in head and lung tumors. Dual-energy CT can achieve quantitative CT imaging based on traditional imaging by dual-energy spectral imaging, and enhance the clarity of head and lung tumors. In this study, we will prospectively explore the image accuracy and delineation accuracy of dual energy CT in radiotherapy to verify whether dual energy CT performs better with conventional CT. conditions: Image Quality and Contouring Accuracy of the Tumor in Radiotherapy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 50 type: ESTIMATED name: Dual energy CT after routine simulation measure: DICE value sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Huan-Hu-Xi status: RECRUITING city: Tianjin state: Tianjin zip: 300381 country: China name: Zhiyong Yuan, Doctor role: CONTACT phone: +86 186 2222 1199 email: zyuan@tmu.edu.cn lat: 39.14222 lon: 117.17667 hasResults: False
nctId: NCT06301087 id: WP-2024-01 briefTitle: Early Detection Neurodevelopmental Disorders of Children and Prevention of Postnatal Depression by Mobile Health App overallStatus: COMPLETED date: 2022-05-01 date: 2024-02-08 date: 2024-02-08 date: 2024-03-08 date: 2024-03-15 name: Weprom class: OTHER name: Kelindi briefSummary: The goal of this observational study is to confirm the impact of using this app adapted to be more specific for screening for 5 neurodevelopmental disorders and to evaluate the mothers' support program on the incidence of postpartum depression in of young parents with a minimum of 1 child under 10 years of age at the time of inclusion and using Malo on a regular basis. The main questions it aims to answer are :
* the median time of the mothers' postnatal depression notifications after childbirth subsequently to the support and prevention program Participants will agree with use of their data conditions: Development, Child conditions: Postnatal Depression studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 55618 type: ACTUAL name: Web Application measure: Time to neurodevelopment desorder diagnostic measure: User's satisfaction measure: Relevance of the neurodevelopmental desorder notification measure: Rate of mothers'postnal depression measure: Time of mothers'postnatal depression sex: ALL maximumAge: 10 Years stdAges: CHILD facility: ILC city: Le Mans country: France lat: 48.0 lon: 0.2 hasResults: False
nctId: NCT06301074 id: HS-10509-101 briefTitle: The Phase I Study of HS-10509 in Chinese Adult Subjects overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-05 date: 2024-10 date: 2024-03-08 date: 2024-03-08 name: Jiangsu Hansoh Pharmaceutical Co., Ltd. class: INDUSTRY briefSummary: The study is to evaluate the safety, tolerability, and PK characteristics following single administration of HS-10509 in healthy adults, and multiple administrations of HS-10509 in patients with schizophrenia.
Participants will have HS-10509 tablets or placebo once in the single ascending dose (SAD) part or once daily for 28 days in the multiple ascending dose (MAD) part. conditions: Schizophrenia studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: For each cohort, participants will be assigned to receive HS-10509 or placebo in parallel primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 80 type: ESTIMATED name: HS-10509 name: Placebo measure: Incidence and severity of adverse events(AE) , serious AEs and AE leading to withdrawal from treatment. measure: Changes from baseline in lab tests measure: Changes from baseline in vital signs measure: Change from baseline in body weight measure: Change from baseline in Electrocardiogram (ECG) measure: Change from Baseline in Columbia - Suicide Severity Rating Scale (C-SSRS) measure: Change from baseline in Abnormal Involuntary Movement Scale (AIMS) measure: Change from baseline in Barnes Akathisia Rating Scale (BARS) measure: Change from baseline in Simpson-Angus Scale (SAS) measure: Cmax measure: Tmax measure: AUC0-t measure: AUC0-∞ measure: λz measure: t½ measure: CL/F measure: Vd/F measure: MRT measure: Css, max measure: Css, min measure: Css, av measure: Tss, max measure: AUCss measure: Change from Baseline in Positive and Negative Syndrome Scale (PANSS) sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The First Hospital of Jilin University city: Changchun state: Jilin country: China name: Xiaojiao Li, Dr. role: CONTACT phone: +86 13514314089 email: Xingxingsuo123456@126.com lat: 43.88 lon: 125.32278 hasResults: False
nctId: NCT06301061 id: PB001 briefTitle: Focal Microvibration and Chronic Lumbosacral Radicular Pain overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-10-01 date: 2026-04-01 date: 2024-03-08 date: 2024-03-08 name: Federico II University class: OTHER briefSummary: The goal of this clinical trial is to investigate the effectiveness of focal microvibration on patients affected by chronic lumbosacral radicular pain. The main question\[s\] it aims to answer are:
Researchers will compare patients treated with focal microvibration to patients treated with a sham device and to patients treated with standard pharmacological therapy. conditions: Pain, Chronic conditions: Lumbosacral Radiculopathy conditions: Radicular; Neuropathic studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 150 type: ESTIMATED name: Equistasi® name: Sham name: Gabapentin; Pregabalin; Duloxetine; Amitriptyline measure: Pain intensity measure: Pain interference in daily life measure: Disability sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06301048 id: BFHHZS20230203 briefTitle: Effectiveness of Endoscopic Papillectomy With Stent for Treating Duodenal Papillary Adenoma overallStatus: COMPLETED date: 2023-11-07 date: 2023-12-07 date: 2023-12-07 date: 2024-03-08 date: 2024-03-08 name: Beijing Friendship Hospital class: OTHER briefSummary: This is a retrospective study, including 79 patients with duodenal papillary adenoma, who treated with Endoscopic Papillectomy (EP) at Beijing friendship hospital. The cohort included patients who underwent EP with or without Pancreatic Duct (PD) and Common Bile Duct (CBD) stent placement. The investigators assessed the outcomes of EP and the impact of stent placement on complications and recurrence rates. conditions: Duodenal Adenoma conditions: Complication of Treatment studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 79 type: ACTUAL name: Stent Placement in Pancreatic and Bile Ducts measure: Rate of complications measure: Rate of complete resection measure: Rate of recurrence sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Beijing Friendship Hospital city: Beijing state: Beijing zip: 100050 country: China lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06301035 id: 2024-01-012 briefTitle: Asymmetric High-flow Nasal Cannula (HFNC) vs Standard HFNC for Post Extubation High-risk Group overallStatus: NOT_YET_RECRUITING date: 2024-03-18 date: 2024-10-31 date: 2024-12-31 date: 2024-03-08 date: 2024-03-08 name: Samsung Medical Center class: OTHER name: Fisher and Paykel Healthcare briefSummary: Background The exacerbation of respiratory failure that occurs after endotracheal intubation often occurs in patients who have received mechanical ventilation therapy, and when it occurs, it emerges as an important issue to consider reintubation of endotracheal intubation. High-flow nasal cannula (HFNC) through nasal cannula is known to produce positive airway pressure and deliver a certain amount of oxygen, and recently reported clinical studies have demonstrated the effect of lowering the risk of reintubation after endotracheal intubation, which is recommended for use in recent clinical practice guidelines. However, in patients at high risk of intubation failure, the combination of high-flow oxygen therapy and non-invasive positive-pressure ventilation therapy rather than the application of high-flow oxygen therapy alone through nasal cannula is helpful in reducing the rate of reintubation of endotracheal intubation. However, an alternative to non-invasive positive-pressure ventilation therapy is needed as there is a possibility of complications such as aspiration pneumonia, maladaptation of the application device (mask), and discomfort, making it difficult to apply it in the field.
Hypothesis 'Asymmetric nasal cannula' reduces work of breath compared to 'standard nasal cannula' in high-risk patients with valvular failure. conditions: Acute Respiratory Failure studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 30 type: ESTIMATED name: Asymmetric High flow nasal cannula name: Standard(symmetric) High flow nasal cannula measure: Respiratory Rate Oxygenation (ROX) Index measure: The Lowest value of SpO2 within 24 hours after extubation measure: PaO2/FiO2 measure: SpO2/FiO2 measure: changes of end-expiratory lung impedance, at each flow rate measured through Electrical Impedance tomography (EIT) measure: Changes in non-homogeneity indicators measured through EIT (changes in Global homeogeneity index) measure: Respiratory rate measure: work of breath (Modified Borg Scale, MBS) measure: systolic blood pressure measure: mean arterial pressure measure: heart rate measure: Rate of reintubation within 7 days measure: Length of ICU stay measure: Length of hospital stay measure: ICU Mortality measure: Hospital Mortality measure: 28 Day Mortality measure: 90 Day Mortality sex: ALL minimumAge: 19 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Samsung Medical Center city: Seoul country: Korea, Republic of name: Hye Rim Chung role: CONTACT phone: +82-2-3410-6399 email: hyerim37.jeong@samsung.com lat: 37.566 lon: 126.9784 hasResults: False
nctId: NCT06301022 id: WXZ-Finerenone briefTitle: Effectiveness and Safety of Finerenone in Chinese CKD Patients Without Diabetes Mellitus overallStatus: RECRUITING date: 2022-12-15 date: 2024-10-31 date: 2024-12-31 date: 2024-03-08 date: 2024-03-08 name: First Affiliated Hospital of Harbin Medical University class: OTHER briefSummary: Background： This study aimed to evaluate the effectiveness and safety of Finerenone in patients with chronic kidney disease (CKD) without diabetes mellitus(DM), however, evidence based on both clinical trails and real-world data are limited.
Patients with CKD without DM were enrolled in this study from December 2022 to December 2024. In conjunction with the established treatment regimen for chronic kidney disease (CKD), study participants were additionally administered Finerenone. To evaluate the therapeutic impact and safety profile of the intervention, three primary biomarkers were monitored: 24-hour urinary protein (UTP), estimated glomerular filtration rate (eGFR), and serum potassium (sK+). These parameters were closely measured on a monthly basis, starting from the point of enrollment and continuing for a duration of twelve months or possibly longer. conditions: Chronic Kidney Diseases studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: RETROSPECTIVE count: 90 type: ESTIMATED measure: 24 hours urinary total protein measure: estimate Gromerular filtration rate measure: serum potassium sex: ALL minimumAge: 20 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: First Aaffiliated Hospital of Harbin Medical University status: RECRUITING city: Harbin state: Heilongjiang zip: 150001 country: China name: XINGZHI WANG, PHD.,MD role: CONTACT phone: +8613904506176 email: WANG.XINGZHI@HRBMU.EDU.CN lat: 45.75 lon: 126.65 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2023-12-15 uploadDate: 2024-02-26T03:42 filename: Prot_SAP_000.pdf size: 207441 hasResults: False