hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06368284 id: IRB-MTP_2022_09_202201170 briefTitle: Perineal Trauma After Jet Ski Accidents and Long-term Functional Outcomes Results acronym: TP-JET overallStatus: RECRUITING date: 2023-01-01 date: 2024-04-01 date: 2024-12-31 date: 2024-04-16 date: 2024-04-16 name: University Hospital, Montpellier class: OTHER briefSummary: French multicentric retrospective cohort study including patients who underwent an ano-perineal trauma following a personal watercraft/jet-ski accident and that were treated in France from January 2017 to December 2023.
Aims of the study were to describe the initial management of the patients and to evaluate the digestive, urological and sexual functional outcomes as well as the quality of life, using validated questionnaires commonly employed in clinical practice. conditions: Perineum; Tear, Traumatic conditions: Anal Tear conditions: Anal Incontinence studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 20 type: ESTIMATED name: Patients who experienced an ano-perineal trauma following a PWC/Jet-Ski accident measure: Rate of fecal incontinence measure: Rate of permanent stoma measure: Rate of acontractile bladder measure: Rate of sexual dysfunction measure: Rate of impact on quality of life sex: ALL minimumAge: 18 Years maximumAge: 99 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Chu Montpellier status: RECRUITING city: Montpellier zip: 34295 country: France name: Thomas BARDOL, MD role: CONTACT phone: 04 67 33 90 69 email: t-bardol@chu-montpellier.fr lat: 43.61092 lon: 3.87723 hasResults: False
nctId: NCT06368271 id: Lipidomix briefTitle: Acute Effects of Dietary Medium-chain Fatty Acids on Lipid Profile acronym: Lipidomix overallStatus: COMPLETED date: 2021-10-01 date: 2024-02-28 date: 2024-02-28 date: 2024-04-16 date: 2024-04-16 name: University of Copenhagen class: OTHER briefSummary: In the present study the plasma lipid profile was elucidated in healthy, lean males by the use of lipidomic analysis in the hours after an acute intake of medium-chain fatty acids (MCT) and long chain fatty acids (LCT),, respectively. In addition oxygen uptake was measured to study energy turnover. conditions: Healthy Nutrition conditions: Diet, Healthy studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: This study is a randomized, double-blinded crossover design. Participants ingest Medium-chain-fatty acids (MCT) or Long-chain fatty acids (LCT) oil on two test days with one-week period between the experimental days. The day prior to the experimental days, the participants consume a eucaloric control diet, and abstain from alcohol and vigorous physical activity to ensure similar conditions on experimental days. primaryPurpose: BASIC_SCIENCE masking: NONE count: 4 type: ACTUAL name: Lipidomics measure: Meal test including medium-chain fatty acids measure: Resting metabolic rate sex: MALE minimumAge: 20 Years maximumAge: 30 Years stdAges: ADULT facility: University of Copenhagen city: Copenhagen zip: 2100 country: Denmark lat: 55.67594 lon: 12.56553 facility: Department of Nutrition, Exercise and Sports city: Copenhagen country: Denmark lat: 55.67594 lon: 12.56553 hasResults: False
nctId: NCT06368258 id: Curr-RYR2023 briefTitle: Middle Term Effect of Red Yeast Rice on Plasma Lipids and Proteoma in Individuals With Suboptimal Cholesterolemia overallStatus: NOT_YET_RECRUITING date: 2024-05-02 date: 2024-12-01 date: 2025-05-02 date: 2024-04-16 date: 2024-04-16 name: University of Bologna class: OTHER briefSummary: The primary purpose of our research will be to evaluate if, in healthy subjects with a low- moderate cardiovascular risk (CV risk\>1% but \< 5%) evidenced by sub-optimal cholesterol levels as per ESC/EAS guidelines (LDL cholesterol \>115 mg/dL, \< 190 mg/dL) supplementation with a red yeast rice food supplement containing less than 3 mg total monacolins per daily dose is able to significantly influence plasma lipid levels. Furthermore, liver and muscle proteomic pattern and vascular response to dietary supplementation will be investigated. conditions: Hypercholesterolemia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 40 type: ESTIMATED name: Red yeast rice name: Placebo measure: Treatment-dependent change in LDL-C measure: Treatment-dependent change in Total Cholesterol measure: Treatment-dependent change in Non-HDL-C measure: Treatment-dependent change in liver parameters measure: Treatment-dependent change in CPK plasma levels measure: Treatment-dependent change in plasma proteomic pattern sex: ALL minimumAge: 30 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: AOU Policlinico S.Orsola-Malpighi city: Bologna country: Italy lat: 44.49381 lon: 11.33875 hasResults: False
nctId: NCT06368245 id: SMART briefTitle: Durability of Suppl. Rod Constructs-SuppleMentAry Rod Technique for Long-segment Posterior Instrumented Spinal Fusions overallStatus: NOT_YET_RECRUITING date: 2024-10-15 date: 2027-12-15 date: 2029-07-31 date: 2024-04-16 date: 2024-04-16 name: AO Foundation, AO Spine class: OTHER briefSummary: This is a multicenter retrospective comparative cohort study. The index surgery for this study is primary or revision long-segment posterior thoracolumbar (TL) instrumented fusion using either a supplementary rod construct or a dual-rod construct. Eligible patients who already had index surgery, will be identified for enrollment through a review of medical records of the participating surgeons at the study sites. conditions: Spinal Fusion studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 1244 type: ESTIMATED name: long-segment posterior TL instrumented fusion measure: Rod fracture (RF) measure: Time to rod fracture measure: Time to rod fracture measure: Configurations of supplementary rod constructs measure: Treatment for rod fracture measure: Recurrent RFs measure: Other mechanical failures measure: Surgical complications sex: ALL minimumAge: 45 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Minnesota Medical Center city: Minneapolis state: Minnesota zip: 55454 country: United States name: David Polly, MD role: CONTACT email: pollydw@umn.edu lat: 44.97997 lon: -93.26384 facility: University of Virginia city: Charlottesville state: Virginia zip: 22908 country: United States name: Justin S Smith, MD, PhD role: CONTACT phone: 434-243-6339 email: jss7f@virginia.edu name: Judith G Beenhakker role: CONTACT email: JGB3P@uvahealth.org lat: 38.02931 lon: -78.47668 hasResults: False
nctId: NCT06368232 id: 19.036.123.125 briefTitle: Nutritional Status After Sleeve Gastrectomy in Morbid Obesity: 6-Month Study overallStatus: COMPLETED date: 2022-02-15 date: 2023-04-15 date: 2023-04-15 date: 2024-04-16 date: 2024-04-16 name: Ankara Yildirim Beyazıt University class: OTHER briefSummary: This study aims to evaluate the nutritional status of morbidly obese patients following gastric bypass surgery. Data from 76 patients aged 19-64, who will be monitored by a dietitian for at least six months, will be analyzed. Preoperative and postoperative biochemical parameters along with anthropometric measurements will assess. conditions: Bariatric Surgery Candidate conditions: Gastrostomy conditions: Obesity studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: RETROSPECTIVE count: 76 type: ACTUAL name: püPatients undergoing bariatric surgery measure: Body Weight measure: BMI (Body Mass Index) measure: Lean Mass measure: Fat Mass measure: Fasting Blood Glucose measure: HbA1c measure: Iron levels measure: Vitamin D level measure: Lipid Profile (Triglycerides, LDL, HDL) sex: ALL minimumAge: 19 Years maximumAge: 64 Years stdAges: ADULT facility: Ankara Yıldırım Beyazıt University city: Ankara zip: 06760 country: Turkey lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06368219 id: 0108161 briefTitle: Propofol or Benzodiazepine Combined With Ketamine for Procedural Sedation in Emergency Setting overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-09 date: 2024-10 date: 2024-04-16 date: 2024-04-16 name: Alexandria University class: OTHER briefSummary: This single blinded parallel randomized clinical trial will be conducted on 50 patients presented to Emergency Department of Alexandria Main University Hospital who are indicated for procedural sedation. All patients included in the study will be allocated randomly using computer software with concealment of randomization in to two groups:
the two groups will be compared as regard incidence of complications World Society of Intravenous Anesthesia (SIVA) international sedation task force to standardize reporting adverse events conditions: Procedural Sedation studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 50 type: ESTIMATED name: ketamine- midazolam versus ketamine- propofol measure: Induction and recovery time for both combinations measure: incidence and severity of adverse events sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06368206 id: OBPM_Calfree2024 briefTitle: Evaluation of the Performance and Safety of the Aktiia Spot-check Optical Blood Pressure Monitoring (OBPM) Device at Fingertip (Aktiia G2C) Against Double Auscultation, and Comparison With Oscillometry and Aktiia Bracelet G2 overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2024-12-31 date: 2024-12-31 date: 2024-04-16 date: 2024-04-23 name: Aktiia SA class: INDUSTRY briefSummary: The present study, OBPM_Calfree2024, with N = 85 participants minimum over 1 visit (lasting around 1h), has been designed to evaluate the performances and safety of the Aktiia.product-G2C that doesn't require any calibrations, as compared against double auscultation for BP reference measurements, and finger pulse oximeter for pulse rate reference measurements, for a cohort of subjects characterized by a wide variety of phenotypes. conditions: Hypertension studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: 1 study cohort that will test investigational device (Aktiia G2C) and Blood Pressure and Pulse Rate references. primaryPurpose: OTHER masking: NONE count: 85 type: ESTIMATED name: Investigational device Aktiia G2C name: Marketed device used as reference for blood pressure monitoring: double auscultation cuff name: Marketed device used as comparative device for blood pressure and pulse rate monitoring: Aktiia Bracelet G2 name: Marketed device used as comparative device for blood pressure and pulse rate monitoring: oscillometric upper-arm cuff name: Marketed device used as comparative device for blood pressure and pulse rate monitoring: oscillometric wrist cuff name: Marketed device used as reference for pulse rate monitoring: pulse finger oximeter measure: Blood pressure mean value of differences measure: Blood pressure standard deviation of differences measure: Pulse rate root-mean-square error sex: ALL minimumAge: 21 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: CHUV city: Lausanne zip: 1011 country: Switzerland lat: 46.516 lon: 6.63282 hasResults: False
nctId: NCT06368193 id: Neuralert 001 briefTitle: The Neuralert Stroke Monitor Pilot Trial overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-05-01 date: 2027-05-01 date: 2024-04-16 date: 2024-04-16 name: Neuralert Technologies LLC class: INDUSTRY briefSummary: This trial aims to demonstrate that the Neuralert Monitoring System will detect strokes before they would be identified by current standard of care. Each patient will be monitored for up to five days, depending on device connectivity or battery duration. Each monitoring session will consist of wearing a Neuralert device on each arm. For this pilot trial, we are interested in learning about Wi-Fi connectivity, successful data transmission, clinical usability, and tolerability. conditions: Stroke conditions: Surgery studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 20 type: ESTIMATED name: Neuralert Monitor measure: Data Aggregation measure: Time to alarm reception measure: Time to alarm reponse measure: Stroke detection sex: ALL minimumAge: 22 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hospital of the University of Pennsylvania city: Philadelphia state: Pennsylvania zip: 19104 country: United States name: Stephanie Cummings role: CONTACT phone: 215-662-3363 email: stephanie.cummings@pennmedicine.upenn.edu name: Scott Kasner, MD role: PRINCIPAL_INVESTIGATOR lat: 39.95233 lon: -75.16379 hasResults: False
nctId: NCT06368180 id: 439106274 briefTitle: The Efficacy of a RAGT & BWSTT on Children With CP overallStatus: COMPLETED date: 2020-08-30 date: 2021-02-21 date: 2021-03-08 date: 2024-04-16 date: 2024-04-16 name: King Saud University class: OTHER briefSummary: This study compared the effects of RAGT and body weight support treadmill training (BWSTT) on spatio-temporal gait parameters and walking capacity among ambulatory children with bilateral CP conditions: Cerebral Palsy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Robotic-assisted gait training Body weight-supported treadmill training primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 40 type: ACTUAL name: Robotic assisted gait training measure: Gait spatio-temporal parameters measure: Six-minute walk test (6MWT) sex: ALL minimumAge: 5 Years maximumAge: 14 Years stdAges: CHILD facility: King Abdu Aziz Medical City city: Riyadh country: Saudi Arabia lat: 24.68773 lon: 46.72185 hasResults: False
nctId: NCT06368167 id: SHR2554-202 briefTitle: A Phase II Study of SHR2554 in Patients With Relapsed or Refractory Follicular Lymphoma overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-04 date: 2027-04 date: 2024-04-16 date: 2024-04-16 name: Jiangsu HengRui Medicine Co., Ltd. class: INDUSTRY briefSummary: The study is being conducted to evaluate the efficacy and safety of SHR2554 in Patients with Relapsed or Refractory Follicular Lymphoma conditions: Follicular Lymphoma studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 105 type: ESTIMATED name: SHR2554 measure: Objective response rate (ORR) assessed by independent review committee (IRC) measure: ORR assessed by investigator measure: Progression free survival measure: Time to Response measure: Duration of response measure: Overall survival sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Peking University Cancer Hospital city: Beijing state: Beijing zip: 100142 country: China name: Yuqin Song role: PRINCIPAL_INVESTIGATOR lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06368154 id: HCHLL-2019-08 briefTitle: Exosome microRNAs as Potential Biomarkers of Metabolic Bone Disease of Prematurity overallStatus: RECRUITING date: 2024-01-01 date: 2026-12-31 date: 2026-12-31 date: 2024-04-16 date: 2024-04-16 name: Hunan Children's Hospital class: OTHER_GOV briefSummary: Metabolic bone disease of prematurity (MBDP) is caused by insufficient content of calcium, phosphorus, and organic protein matrix in preterm infants or bone metabolism disorder, which is one of the complications affecting the quality of life of preterm infants. The early symptoms of MBDP are insidious, and there is no unified and clear diagnostic method. The diagnosis is mostly based on typical clinical manifestations and X-ray findings, but at this time, bone mineral density has decreased significantly, so early detection and diagnosis are difficult. Studies have shown that exosomal micrornas have biological characteristics and targeting specificity, and can be used as new molecular diagnostic markers for diseases. Several studies have reported the use of plasma or serum microRNAs as molecular markers for early prediction of bone diseases. In our previous study, we extracted plasma exosomes from preterm infants for high-throughput sequencing of microRNAs, and identified differentially expressed micrornas related to bone metabolism. In this study, exosomes were used as carriers, and digital PCR was used to verify the specificity and sensitivity of plasma exosomal microRNA as biomarkers of MBDP in a large sample size. The above biomarkers were compared and verified before and after treatment in children with MBDP. Further revealing plasma exosomal microRNA as a biological indicator for evaluating the efficacy of MBDP may improve the diagnostic level of MBDP, improve the outcome and prognosis of very low birth weight preterm infants, thereby improving global health and reducing socioeconomic costs. conditions: Exosomes conditions: Newborn conditions: Bone Diseases, Metabolic studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 200 type: ESTIMATED measure: exosomes sex: ALL minimumAge: 0 Hours maximumAge: 72 Hours stdAges: CHILD facility: Hunan Children's Hospital status: RECRUITING city: Changsha state: Hunan zip: 410007 country: China name: yinzhi y liu, master role: CONTACT phone: 13467532228 email: liuyinzhi0837@163.com lat: 28.19874 lon: 112.97087 hasResults: False
nctId: NCT06368141 id: 2023294 briefTitle: Neoadjuvant Chemotherapy Plus Sequential Immune Checkpoint Inhibitor (ICI) Therapy in Locally Advanced Colon Cancer acronym: NeoCHIC overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-02-28 date: 2026-04-30 date: 2024-04-16 date: 2024-04-16 name: Ruijin Hospital class: OTHER briefSummary: The goal of this clinical trial is to learn the effect of neoadjuvant chemotherapy plus sequential immune checkpoint inhibitor (ICI) therapy in locally advanced colon cancer. The main questions it aims to answer are:
* a standard complete mesocolic excision (CME) operation. conditions: Colon Cancer studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 56 type: ESTIMATED name: Serplulimab name: Capecitabine name: Oxaliplatin measure: pathologic complete response sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ruijin Hospital city: Shanghai state: Shanghai zip: 200025 country: China lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06368128 id: HS-24_51 briefTitle: Climbing Lifestyle Intervention for Modifying Physical Activity Behaviors: Pilot Study acronym: CLIMB overallStatus: RECRUITING date: 2024-04-10 date: 2024-12-31 date: 2024-12-31 date: 2024-04-16 date: 2024-04-16 name: Northern Michigan University class: OTHER briefSummary: The aim of this pilot study is to determine the effects of a 12-week indoor rock climbing training program on heart health, mental health, and behavioral health in generally healthy adults aged 18-35 years old who do not exercise. Participants will learn to rock climb using ropes on an indoor rock climbing wall and participate in the training program 2-3 days per week for 60 minutes each session over 12 weeks. Health outcomes will be measured at 4 time points over the course of the study (pre-intervention, 6-weeks/mid-intervention, 12-weeks/post-intervention, and 24-weeks post-intervention). conditions: Lifestyle Factors conditions: Physical Inactivity conditions: Quality of Life studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized controlled trial with participants allocated to either a control or intervention group; comparison between groups and within groups primaryPurpose: PREVENTION masking: NONE count: 12 type: ESTIMATED name: Indoor Rock Climbing Exercise Training Program measure: Fasting lipids measure: Fasting glucose measure: Hemoglobin a1c measure: Physical activity and sedentary behavior measure: Sedentary behavior bouts (30 min, 60 min, >60 min) measure: Cardiorespiratory fitness measure: Muscular fitness measure: Handgrip strength asymmetry measure: Lower-body dynamic balance measure: Health-related quality of life using CDC Health-Related Quality of Life Scale measure: Exercise self-efficacy measured via Self-efficacy for exercise scale measure: Perceptions of exercise measured via Views and Attitudes Toward Exercise Scale measure: Perceived stress measure: Blood pressure measure: Body composition measure: Bone density sex: ALL minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: Northern Michigan University status: RECRUITING city: Marquette state: Michigan zip: 49855 country: United States name: Lisa Eckert, PhD role: CONTACT phone: 906-227-1291 email: leckert@nmu.edu name: Megan C Nelson, PhD role: PRINCIPAL_INVESTIGATOR lat: 46.54354 lon: -87.39542 hasResults: False
nctId: NCT06368102 id: R6-03 briefTitle: Prophylactic Effects for Preventing Surgical Site Infection in Third Molar Surgery overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-04 date: 2025-08 date: 2024-04-16 date: 2024-04-16 name: Uji Takeda Hospital class: OTHER briefSummary: The purpose of this study is to determine the incidence of surgical site infection (SSIs) after third molar surgery for different duration of intravenous ampicillin administration. conditions: Surgical Site Infection studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 70 type: ESTIMATED name: Ampicillin measure: Occurrence of surgical site infection measure: Occurrence of alveolar osteitis sex: ALL minimumAge: 20 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06368089 id: REC.66-474-30-2 id: MR-PSU:66-30-21-406 type: OTHER_GRANT domain: Faculty of Medicine, Prince of Songkla University briefTitle: Short Effects of SIMT and EM in Prolonged Mechanically Ventilated Patients overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-02 date: 2026-03 date: 2024-04-16 date: 2024-04-16 name: Prince of Songkla University class: OTHER briefSummary: Using mechanical ventilation for more than 18 hours can affect respiratory muscle and postural muscle control, making it difficult to wean off the ventilator and reducing mobility. The aim of this study is to:
2. Compare the success rate of weaning and the duration of weaning between the respiratory muscle strength training and the early mobilization program. conditions: Ventilator Dependent studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: randomization primaryPurpose: TREATMENT masking: NONE count: 46 type: ESTIMATED name: Inspiratory muscle training (IMT) group name: Early mobilization (EM) group measure: Maximum inspiratory pressure (MIP) measure: Dynamic lung compliance (Cdyn) measure: Weaning time measure: Weaning outcome measure: Grip strength measure: chest wall expansion sex: ALL minimumAge: 40 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Medical Respiratory Care Unit (MRCU), Prince of Songklanakarind Hospital city: Songkhla zip: 90110 country: Thailand lat: 7.19882 lon: 100.5951 hasResults: False