hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06288009 id: 2135389 briefTitle: Outcomes of Running Locking Suture vs Standard Running Suture in Surgical Wounds overallStatus: RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-06-01 date: 2024-03-01 date: 2024-03-01 name: University of California, Davis class: OTHER briefSummary: When patients have surgery on the head and face, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring. Several studies have been done to test ways to close wounds that reduce scarring. The most commonly performed closure technique uses running sutures, where a single strand of suture is continued along the length of the wound with a series of uninterrupted stiches. However, alternative closure techniques exist such as the running locking suture, which can offer advantages such as improved tension and thus reduce post-operative complications with better aesthetic outcome. In this study, half the wound will be stitched with standard running sutures and the other half will be stitched with running locking sutures. This will allow us to see if the side with running locking sutures heals with less scarring. conditions: Scarring studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: SINGLE maskingDescription: Two blinded observers will record their scores independently using the POSAS instrument. whoMasked: OUTCOMES_ASSESSOR count: 50 type: ESTIMATED name: Running locking suture name: Standard running suture measure: Observer Scar Assessment as measured by Patient Observer Scar Assessment Score (POSAS) measure: Patient Scar Assessment as measured by Patient Observer Scar Assessment Score (POSAS) measure: Width of Scar as measured using Trace-to-Tape Method measure: Complications or Adverse Events from Treatment sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of California, Davis - Dermatology Department status: RECRUITING city: Sacramento state: California zip: 95816 country: United States name: John Robb, BS role: CONTACT phone: 916-551-2636 email: jmrobb@ucdavis.edu name: Daniel Eisen, MD role: CONTACT phone: 916-551-2611 email: dbeisen@ucdavis.edu name: Daniel Eisen, MD role: PRINCIPAL_INVESTIGATOR name: Keemberly Kim, MD role: SUB_INVESTIGATOR name: Samantha Daniel, MD role: SUB_INVESTIGATOR lat: 38.58157 lon: -121.4944 hasResults: False
nctId: NCT06287996 id: 23MMHIS503e NA briefTitle: Effects of Warm Water Footbath Intervention on Sleep Quality , Fatigue and Heart Rate Variability in Patients With Heart Failure overallStatus: ENROLLING_BY_INVITATION date: 2024-02-23 date: 2024-06-01 date: 2024-08-01 date: 2024-03-01 date: 2024-03-01 name: Mackay Memorial Hospital class: OTHER briefSummary: This study adopted an experimental research design to explore the effects of a warm water foot bath program on fatigue, sleep, and heart rate variability in patients with heart failure. The subjects of the study were heart failure patients in the cardiology outpatient department. The patients were randomly assigned to the experimental group and the control group. The control group received routine care and wore an actigraph. The experimental group received 4 additional care in addition to routine care and wearing an actigraph. Weekly warm water foot bath, data collection includes subjective sleep quality and fatigue level, physiological measurements: sleep quality-sleep time and efficiency, and heart rate variability index. conditions: Footbath conditions: Heart Failure conditions: Sleep Quality conditions: Fatigue conditions: Heart Rate Variability studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 76 type: ESTIMATED name: footbath and actigraphy name: actigraphy measure: sleep quality measure: fatigue measure: heart rate variability sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mackay Memorial Hospital city: Taipei state: Zhongshan zip: 104 country: Taiwan lat: 25.04776 lon: 121.53185 hasResults: False
nctId: NCT06287983 id: KayseriCHIMT001 briefTitle: Effect of Inspiratory Muscle Training on Respiratory Functions and Exercise Capacity overallStatus: RECRUITING date: 2023-06-01 date: 2024-03-31 date: 2024-05-15 date: 2024-03-01 date: 2024-03-07 name: Kayseri City Hospital class: OTHER_GOV briefSummary: In this study, we aimed to evaluate the effect of Anti- tumor necrosis factor (TNF) treatment on pulmonary functions in patients with AS and to evaluate the pulmonary functions and exercise performance of patients by adding inspiratory muscle training to spinal mobility exercises in patients with AS using Anti-TNF. We also aimed to investigate the relationship between these parameters and disease activity, spinal mobility and quality of life. conditions: Ankylosing Spondylitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: A total of 44 patients were randomly divided into 2 groups using the sealed envelope randomization method. The exercise program will be applied to both groups 3 sessions a week for 60 minutes for 6 weeks. Inspiratory muscle training will also be added to the intervention group. Patients included in the study; At weeks 0, 6, 12 and 24, BASDAI (Bath Ankylosing Spondylitis Disease Activity Index), BASFI (Bath Ankylosing Spondylitis Functional Index), ASQoL (The Ankylosing Spondylitis Quality of Life), Modified Borg Scale, Visual Analog scale (VAS) and maximum Dyspnea measurement during exercise, 6-minute walk test, chest expansion measurement and respiratory function test (spirometry) will be evaluated. primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 44 type: ESTIMATED name: Inspiratory Muscle Trainer (IMT) (POWERbreathe Medic Classic) name: The Sample Spondylitis Exercise Program measure: Respiratory function test (Spirometry) measure: Bath Ankylosing Spondylitis Disease Activity Index (BASDAI): measure: Bath Ankylosing Spondylitis Functional Index (BASFI) measure: Ankylosing Spondylitis Quality of Life Questionnaire (ASQoL) measure: Modified Borg Scale measure: Measurement of dyspnea at maximum exercise with the Visual Analog Scale (VAS) measure: 6-minute walk test (6MWT) measure: Chest expansion measurement sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Health Sciences University, Kayseri Medicine Faculty, Kayseri City Hospital status: RECRUITING city: Kayseri zip: 38080 country: Turkey name: Havva Talay Çalış, Prof role: CONTACT phone: +90352 315 77 00 phoneExt: 61244 email: htalaycalis@yahoo.com name: Esra Yaprak Tas, MD role: CONTACT phone: +905062007571 email: yaprak8100@gmail.com lat: 38.73222 lon: 35.48528 hasResults: False
nctId: NCT06287970 id: 2023-250-KY briefTitle: TaVNS Improves the Symptoms of Patients With Moderate to Severe CP/CPPS overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2026-12-31 date: 2027-02-18 date: 2024-03-01 date: 2024-03-21 name: Jiani Wu class: OTHER briefSummary: This trial aims to evaluate the efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS) for moderate to severe chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). This study is a prospective, randomized, controlled trial. A total of 68 patients with CP/CPPS will be recruited. After baseline assessment, the patients will be randomized into taVNS group (n = 34) and sham-taVNS group (n = 34). The intervention of two group will last for 4 weeks with a 8-week follow-up period after the treatment. The National Institutes of Health chronic Prostatitis Symptom Score index (NIH-CPSI), International Prostate Symptom Score Scale (IPSS), European quality of Life-5 Dimensions Questionnaire (EQ-5D), self-rating anxiety Scale (SAS) and self-rating depression scale (SDS) will be assessed. The adverse events during the whole study will be recorded detailedly. conditions: Chronic Prostatitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 68 type: ESTIMATED name: Transcutaneous Auricular Vagus Nerve Stimulation name: Sham Transcutaneous Auricular Vagus Nerve Stimulation measure: Change from baseline in National Institute of Health Chronic Prostatitis Symptom Index(NIH-CPSI) total score at week 4 measure: Change from baseline in National Institute of Health Chronic Prostatitis Symptom Index(NIH-CPSI) total score at week 8 and week 12 measure: The changes from baseline of NIH-CPSI pain score, urinary score and quality of life score, respectively at week 4, 8 and 12 measure: Proportion of responders at week 4, 8 and 12 measure: The change from baseline in International Prostate Symptom Score (IPSS) score at week 4, 8 and 12 measure: The change from baseline in EuroQol Five Dimensions Questionnaire (EQ-5D) at week 4, 8 and 12 measure: The change from baseline in Self-rating Anxiety Scale (SAS) at week 4, 8 and 12 measure: The change from baseline in the Self-rating Depression Scale (SDS) at week 4, 8 and 12 measure: Evaluation of patient expectations measure: Blinding Evaluation measure: Incidence of Treatment-Emergent Adverse Events sex: MALE minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Guang'anmen Hospita, China Academy of Chinese Medical Sciences city: Beijing state: Beijing zip: 100053 country: China name: Jiani Wu role: CONTACT phone: +8613426116653 email: jiani_wu@aliyun.com lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06287957 id: IU-DHF-AG-01 briefTitle: Chitosan Brushes vs Air-Abrasive Devices on Peri-implant Mucositis Treatment: A Randomized Clinical overallStatus: RECRUITING date: 2024-03-01 date: 2024-10-01 date: 2025-02-15 date: 2024-03-01 date: 2024-03-01 name: Istanbul University class: OTHER briefSummary: Bleeding on probing (0,1,2,3), plaque index (+,-) and pocket probing depth will be recorded for each visit. Before the procedure, the patient will be randomly assigned to one of four groups and records will be kept. In the frst visit of the patient, necessary actions will be taken according to the group to which the patient is assigned. The implant periphery of the patients assigned to the chitosan brush group will be debrided with a chitosan brush with circular movements. The implants of the patients assigned to the air abrasive device group will be cleaned in the same way with circular movements. The debrided area of both groups will be washed with sterile serum after the treatment. Patients will be called at the 2nd, 4th and 12th weeks and compared with the records kept. conditions: Peri-implant Mucositis conditions: Peri-Implantitis conditions: Bleeding on Probing conditions: Periodontal Pocket studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: There are going to be 4 treatment groups. Group 1: Mini Implant Platform treated with Labrida Bioclean Group 2: Regular Implant Platform treated with Labrida Bioclean Group 3: Mini Implant Platform treated with Air-Flow Device Group 4: Regular Implant Platform treated with Air-Flow Device primaryPurpose: PREVENTION masking: NONE count: 54 type: ESTIMATED name: Labrida BioClean name: EMS Handy 3.0 Perio Premium measure: Probing Depth measure: Bleeding on Probing measure: Plaque Index sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Istanbul University status: RECRUITING city: Istanbul state: Fatih zip: 34080 country: Turkey name: Alper Gultekin, Assistant Professor role: CONTACT phone: +90 5326757236 email: alperg@istanbul.edu.tr name: Kerem Bahceci, PhD Candidate role: CONTACT phone: +90 5317132633 email: kerembhc@gmail.com lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06287931 id: sdllycyy001 briefTitle: Probiotics for Gallstones in Post-bariatric Surgery Patients overallStatus: RECRUITING date: 2024-01-01 date: 2025-06-01 date: 2025-06-01 date: 2024-03-01 date: 2024-03-01 name: Shandong Linglong Yingcheng Hospital class: NETWORK briefSummary: Obesity is an increasing epidemic worldwide and has a significant impact on human health and socioeconomics. Multiple studies have shown that bariatric surgery increases the risk of postoperative gallbladder stones. Contributing factors to gallstone formation include gallbladder motility and bile supersaturation due to rapid weight loss and cholesterol mobilization. At present, the prevention and treatment of gallbladder stones in obese patients after bariatric surgery are still controversial. In recent years, the study of ursodeoxycholic acid in preventing gallbladder stone formation after bariatric surgery has become a research hotspot. At the same time, other studies have shown that taking probiotics or digestive enzymes may improve gastrointestinal symptoms and improve quality of life after bariatric surgery. Therefore, the purpose of this study was to determine the ability of probiotics to prevent gallstone formation after bariatric surgery and to evaluate the impact of oral probiotics on quality of life in patients after bariatric surgery. conditions: Bariatric Surgery Candidate conditions: Gallstone conditions: Gallstone Attack conditions: Gastrointestinal Quality of Life Index conditions: Probiotics studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 400 type: ESTIMATED name: Ursodoxycholic acid group name: Bifidobacterium group measure: The incidence of gallstones in bariatric surgery patients sex: ALL minimumAge: 20 Years maximumAge: 60 Years stdAges: ADULT facility: Shandong Linglong Yingcheng Hospital status: RECRUITING city: Yantai state: Shandong zip: 264000 country: China name: Xuan Qiu, MD role: CONTACT phone: 8618354280081 email: qiuxuan100@163.com name: Ni Wang, MD role: CONTACT phone: 8618705353551 email: wangni1989@163.com lat: 37.47649 lon: 121.44081 hasResults: False
nctId: NCT06287918 id: 3HP-2827-101 briefTitle: A First-in-human Study of 3HP-2827 in Patients With Unresectable or Metastatic Solid Tumors With FGFR2 Alterations overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2028-03 date: 2028-06 date: 2024-03-01 date: 2024-04-11 name: 3H (Suzhou) Pharmaceuticals Co., Ltd. class: INDUSTRY briefSummary: The study is being conducted to evaluate the safety, tolerability, efficacy, pharmacokinetics, and pharmacodynamics of 3HP-2827 in the treatment of unresectable or metastatic solid tumors with FGFR2 alterations. Patients will be enrolled in two stages: dose escalation stage (Stage I) and expansion stage (Stage II). conditions: Solid Tumors With FGFR2 Alterations, Adult studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: NONE count: 130 type: ESTIMATED name: 3HP-2827 measure: Dose Escalation Stage- incidence of adverse events (AEs) measure: Dose Escalation Stage- incidence of dose-limiting toxicities (DLTs) measure: Dose Escalation Stage -Percentage of Participants With Changes From Baseline in Targeted Vital Signs measure: Dose Escalation Stage -Percentage of Participants With Changes From Baseline in Targeted Clinical Laboratory Test Results measure: Dose Escalation Stage -Percentage of Participants With Changes From Baseline in Targeted ECG Parameters measure: Dose Escalation Stage -determine the maximum tolerated dose (MTD) and/or the recommended dose (RD) for expansion stage or recommended Phase II dose (RP2D) of 3HP-2827 measure: Expansion stage -Objective response rate（ORR） measure: Plasma Concentration of 3HP-2827 and/or its major metabolites measure: Duration of Response (DOR) as assessed by RECIST v1.1 measure: Progression-free survival (PFS) as assessed by RECIST v1.1 measure: Overall survival measure: Dose escalation stage - Objective Response Rate (ORR) measure: Expansion Stage- incidence of adverse events (AEs) measure: Expansion Stage -Percentage of Participants With Changes From Baseline in Targeted Vital Signs measure: Expansion Stage -Percentage of Participants With Changes From Baseline in Targeted Clinical Laboratory Test Results measure: Expansion Stage -Percentage of Participants With Changes From Baseline in Targeted ECG Parameters sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mayo Clinic city: Phoenix state: Arizona zip: 85054 country: United States lat: 33.44838 lon: -112.07404 facility: The University of Texas MD Anderson Cancer Center city: Houston state: Texas zip: 77030 country: United States lat: 29.76328 lon: -95.36327 hasResults: False
nctId: NCT06287905 id: Soh-Med-23-02-24 briefTitle: A Comparative Study of Using Scorpion Antivenom Versus Scorpion Antivenom and Prazosin overallStatus: RECRUITING date: 2023-02-01 date: 2024-07-01 date: 2024-07-01 date: 2024-03-01 date: 2024-03-01 name: Sohag University class: OTHER briefSummary: Interventional study designed for the evaluation of characters and the outcome of scorpion sting patients will admit to Sohag University Hospitals in 2 randomized groups. The first group will receive scorpion antivenom only whether by the intravenous or the intramuscular route of administration. The second group will receive a combination of prazosin plus scorpion antivenom whether by the intravenous or the intramuscular route of administration. Both groups will receive proper first aid and supportive treatment conditions: Morality studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: observational comparative primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Simple randomization whoMasked: PARTICIPANT count: 80 type: ESTIMATED name: Prazosin Oral Tablet measure: Mortality measure: Morbidity sex: ALL minimumAge: 1 Year maximumAge: 70 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Meray Medhat Shokry Zaghary status: RECRUITING city: Sohag zip: 82515 country: Egypt name: Meray M Shokry Zaghary role: CONTACT phone: +201028911003 email: drevanho2013@gmail.com name: Mai M Abd El Kader role: CONTACT phone: +201028911003 email: drevanho2013@gmail.com lat: 26.55695 lon: 31.69478 hasResults: False
nctId: NCT06287892 id: AI-ECG-HCM briefTitle: Diagnosis of HCM With AI-ECG overallStatus: RECRUITING date: 2024-01-01 date: 2024-12-31 date: 2024-12-31 date: 2024-03-01 date: 2024-03-06 name: Shanghai Zhongshan Hospital class: OTHER briefSummary: The study aims to establish a diagnostic model of hypertrophic cardiomyopathy with artificial intelligence-enhanced electrocardiogram. conditions: Hypertrophic Cardiomyopathy studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: RETROSPECTIVE count: 10000 type: ESTIMATED measure: Diagnosis of HCM with AI-ECG sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: 180 Fenglin Road status: RECRUITING city: Shanghai zip: 200032 country: China name: Yixiu Liang, MD role: CONTACT phone: +8664041990 phoneExt: 612844 email: liang.yixiu@zs-hospital.sh.cn lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06287879 id: 20231121 briefTitle: Function and Morphological Characteristics of Meibomian Gland in Patients With Renal Anemia overallStatus: RECRUITING date: 2023-04-01 date: 2024-12-20 date: 2024-12-30 date: 2024-03-01 date: 2024-03-01 name: Zhongnan Hospital class: OTHER briefSummary: Renal anemia refers to anemia in which the absolute or relative production of erythropoietin (EPO) is insufficient due to various kidney diseases, and uremic toxins affect erythropoietin production and its lifespan. Common treatment drugs for renal anemia include erythropoietin EPO and Roxadustat (FG-4592).
This study will help to determine the function and morphological characteristics of meibomian gland in patients with renal anemia conditions: Dry Eye conditions: MGD-Meibomian Gland Dysfunction studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 50 type: ESTIMATED name: Dry eye examination measure: Lacrimal river height measure: tear break-up time measure: tear-film lipid layer thickness measure: meibomian glands two-dimensional digital infrared images sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Zhongnan Hospital of Wuhan University status: RECRUITING city: Wuhan state: Hubei zip: 430071 country: China name: Min Ke, Doctor role: CONTACT phone: +86-18672395959 email: keminyk@163.com lat: 30.58333 lon: 114.26667 hasResults: False
nctId: NCT06287866 id: 2099470 briefTitle: Pinch Grafting Versus Second Intention Wound Healing for Mohs Micrographic Surgery Defects on the Scalp overallStatus: RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-06-01 date: 2024-03-01 date: 2024-03-01 name: University of California, Davis class: OTHER briefSummary: Oftentimes, following surgery on the scalp, wounds are left to heal by themselves. This is called "second intention." Open wounds left to heal on the scalp often take 8 weeks or more to completely heal. We are investigating how second intention closure compares to another established reconstruction technique, called "pinch graft." In the pinch graft technique, we numb and then shave off a thin piece of skin (usually from the groin area) and place it in the wound bed it (also known as "grafting"), to encourage growth of new healthy skin. This study will compare time-to-healing in the second intention method versus the pinch graft method. conditions: Scarring studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: SINGLE maskingDescription: Two blinded observers will record their scores independently using the POSAS instrument. whoMasked: OUTCOMES_ASSESSOR count: 50 type: ESTIMATED name: Pinch Graft measure: Time to re-epithelialization measure: Observer Scar Assessment as measured by Patient Observer Scar Assessment Score (POSAS) measure: Patient Scar Assessment as measured by Patient Observer Scar Assessment Score (POSAS) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of California, Davis - Dermatology Department status: RECRUITING city: Sacramento state: California zip: 95816 country: United States name: John Robb, BS role: CONTACT phone: 916-551-2636 email: jmrobb@ucdavis.edu name: Daniel Eisen, MD role: CONTACT phone: 916-551-2611 email: dbeisen@ucdavis.edu name: Daniel Eisen, MD role: PRINCIPAL_INVESTIGATOR name: Keemberly Kim, MD role: SUB_INVESTIGATOR name: Ilana Breen, MD role: SUB_INVESTIGATOR lat: 38.58157 lon: -121.4944 hasResults: False
nctId: NCT06287853 id: EMBODY-004 briefTitle: Tapestry Rotator Cuff Repair PMCF overallStatus: NOT_YET_RECRUITING date: 2024-06-30 date: 2028-06-30 date: 2029-06-30 date: 2024-03-01 date: 2024-03-01 name: Zimmer Biomet class: INDUSTRY briefSummary: The study design is a prospective, multi-center, single-arm, non-randomized, and noncontrolled post market clinical follow-up study involving orthopedic surgeons skilled in arthroscopic rotator cuff repair as determined by the Sponsor. conditions: Rotator Cuff Tears conditions: Rotator Cuff Injuries studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 170 type: ESTIMATED name: Tapestry Biointegrative Implant measure: Re-tear rate after arthroscopic rotator cuff repair measure: The American Shoulder and Elbow Surgeons (ASES) Score measure: Constant-Murley Score (CMS) measure: The Single Assessment Numeric Evaluation (SANE) Score measure: EQ-5D-5L (EuroQol) measure: Return to Work/Activity measure: Patient Satisfaction measure: Adverse Event measure: MRI Sugaya Classification measure: MRI Goutallier Classification sex: ALL minimumAge: 21 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False