hackint0sh/New-Dataset huggingface dataset:
Participants underwent eight sessions, three per week, with the BTL-6000 spinal decompression system. The study did not have a comparison group. conditions: Low Back Pain conditions: Sciatica conditions: Lumbar Disc Herniation studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 39 type: ACTUAL name: Spinal decompression with BTL-6000 spinal decompression system (BTL Industries Ltd.) measure: Self-reported disability measure: Pain intensity sex: ALL minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: Hospital Civil de Guadalajara Fray Antonio Alcalde city: Guadalajara state: Jalisco zip: 44280 country: Mexico lat: 20.66682 lon: -103.39182 hasResults: False
nctId: NCT06275737 id: POP-UP G-128 briefTitle: POP-UP: a Single-arm, Two-cohort Study: Trimodal Prehab for Upper GI and Pancreatic Cancer acronym: POP-UP overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2027-03 date: 2027-03 date: 2024-02-23 date: 2024-02-23 name: GERCOR - Multidisciplinary Oncology Cooperative Group class: OTHER briefSummary: This is a multicenter, two-cohort, open-label, single-arm feasibility study. The primary objective is to assess the feasibility of the 8-week trimodal prehabilitation program alongside perioperative triplet chemotherapy in eligible patients with localized pancreatic ductal adenocarcinoma (PDAC) or oesogastric cancer (OGC) . conditions: Pancreatic Ductal Adenocarcinoma conditions: Esophageal Cancer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Two-cohort, open-label, single-arm feasibility study primaryPurpose: OTHER masking: NONE count: 72 type: ESTIMATED name: Prehabilitation program measure: Rate of patients with successful completion of an 8-week trimodal prehabilitation program measure: Success rate (as defined above) for Adapted Physical Activity (APA), nutritional, and psychological interventions measured separately. measure: Health-related quality of life (HRQoL) assessment measure: Rate of patients who start and complete post-habilitation Adapted Physical Activity (APA) sessions measure: Nutritional status assessment measure: Physical/functional test assessment measure: Number of patients with reduced chemotherapy tolerance measure: Number of patients with chemotherapy dose modification measure: Rate of patients who complete the strategy measure: Number of patients with Granulocyte-colony stimulating factor (G-CSF) prescription and grade ≥ 2 neutropenia measure: Rate of patients with exocrine pancreatic insufficiency and the dose of pancreatic enzyme consumption measure: Rate of surgical complications measure: Overall survival (OS) assessment measure: Disease-free survival (DFS) assessment measure: Adherence to Adapted Physical Activity (APA) program assessment measure: Physical activity behavior changes assessment measure: Nurse coordination sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06275711 id: 223K003 briefTitle: The Effect of Therapeutic Communication Methods on the Psychological State of Children overallStatus: COMPLETED date: 2023-11-30 date: 2023-12-06 date: 2023-12-06 date: 2024-02-23 date: 2024-02-23 name: Gazi University class: OTHER name: The Scientific and Technological Research Council of Turkey briefSummary: Earthquake is a disaster that causes physical, psychological, social, economic and cultural losses for individuals and affects/interrupts all age groups and normal life. Children are a group that is more affected by the earthquake than other members of the society and are exposed to its long-term effects. Children who have experienced earthquakes and continue to stay in the earthquake zone experience physical, economic, and social problems. In addition, the emotional and psychological development of these children is negatively affected.
Due to the earthquake that occurred on 6 February 2023 affecting 11 provinces in our country, the needs in the field vary. After the acute period (first 1 month), children need psychological support. Problems that cannot be solved in the early period may cause health and behavioural problems in children in later ages and adulthood. In this context, approaching children with appropriate therapeutic communication methods positively affects their psychological well-being and directly affected physical resilience by enabling them to express their emotions.
H4. After the therapeutic communication programme, children's scores on the Child and Adolescent Psychological Resilience Scale increase. conditions: Psychological studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Pre-test post-test quasi-experimental study primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 65 type: ACTUAL name: Therapeutic communication methods measure: State Anxiety Scale on Children measure: Trait Anxiety Scale on Children measure: Me and My Feelings Scale on Children measure: Child and Youth Resilience Measure sex: ALL minimumAge: 8 Years maximumAge: 12 Years stdAges: CHILD facility: K-1 Container City city: Adıyaman state: Altınsehir zip: 02040 country: Turkey lat: 37.76441 lon: 38.27629 hasResults: False
nctId: NCT06275698 id: RD2023-14 HONEY-POT id: 323188 type: OTHER domain: IRAS id: 56974 type: OTHER_GRANT domain: CPMS briefTitle: HONEY for the Treatment of POst-Tonsillectomy Pain acronym: HONEY-POT overallStatus: RECRUITING date: 2023-09-04 date: 2025-09-04 date: 2025-09-04 date: 2024-02-23 date: 2024-02-23 name: East and North Hertfordshire NHS Trust class: OTHER_GOV name: Manuka Doctor UK Ltd name: National Institute for Health Research, United Kingdom briefSummary: Double-blind, randomised, placebo controlled, single-site trial in adults to compare the effect of Manuka honey with standard of care compared to placebo with standard of care on post-tonsillectomy pain and postoperative outcomes.
Main aim is to investigate a potential improvement in post-tonsillectomy pain control, with a low cost and freely available alternative to conventional analgesics. Recent systematic review and multidisciplinary consensus suggest a potential role for the inclusion of honey for this purpose. Clinical efficacy over placebo remains to be conclusively demonstrated in robust clinical trials. conditions: Post Surgical Pain conditions: Analgesia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Intervention arm - Manuka honey, to be taken per-oral 15ml TDS for 14 days post-tonsillectomy.
Placebo - sugar-based syrup, thickened with sodium alginate and with honey flavouring, to be taken per-oral 15ml TDS for 14 days post-tonsillectomy. primaryPurpose: TREATMENT masking: TRIPLE maskingDescription: Intervention (Manuka honey) and placebo will be supplied in identical opaque jars with identical labels apart from individual unique ID numbers to facilitate un-blinding in the case of adverse events.
Neither the patient nor the researcher collecting data will be aware of which arm the patient has been enrolled onto. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 100 type: ESTIMATED name: Manuka honey MGO 1000 name: Sugar-based syrup, thickened with sodium alginate and flavoured with honey flavouring measure: VAS pain scores measure: Number and frequency of concurrent analgesia usage measure: Rate of readmission to hospital measure: Rate of secondary haemorrhage measure: Rate of infection requiring antibiotics treatment measure: Speed of return to work sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Lister Hospital status: RECRUITING city: Stevenage zip: SG1 4AB country: United Kingdom name: Toral Odedra role: CONTACT phone: 07918 360 060 email: toral.odedra@nhs.net lat: 51.90224 lon: -0.20256 hasResults: False
nctId: NCT06275685 id: CIP-0001510 briefTitle: Forecasting Seizures Using Intelligent Wearable Technology for Health Tracking acronym: Foresight overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-06 date: 2026-06 date: 2024-02-23 date: 2024-02-23 name: Empatica, Inc. class: INDUSTRY briefSummary: The goal of this interventional study is to develop a personalized seizure risk forecast tool in people with epilepsy.
Researchers will compare a group that does not have access to the forecast tool to a group that does and see if it is accurate and if people with it report that it improved their quality of life. conditions: Epilepsy; Seizure studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 3000 type: ESTIMATED name: SeizureWise algorithm name: Multi-day Visualizations measure: Sensitivity of SeizureWise measure: Change in QoL and psychological health indicators using the Quality of life in epilepsy (QOLIE-10-P) measure: Qualitative assessment of multi-day visualizations measure: Stress level with visualizations using the brief epilepsy anxiety survey instrument (brEASI-8) measure: Modifiable behavior change measure: Accuracy of SeizureWise low-likelihood forecast measure: Accuracy of SeizureWise high-likelihood forecast sex: ALL minimumAge: 6 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06275659 id: CT-100-D-003 briefTitle: An Exploratory Study to Evaluate a Digital Intervention to Disrupt Scratching in Atopic Dermatitis and Psoriasis overallStatus: ACTIVE_NOT_RECRUITING date: 2023-12-04 date: 2024-02-23 date: 2024-03-18 date: 2024-02-23 date: 2024-03-08 name: Click Therapeutics, Inc. class: INDUSTRY briefSummary: CT-100 is a platform that provides interactive, software based therapeutic components that may be used as part of a treatment in future software-based prescription digital therapeutics. One class of CT-100 components are Digital Neuro-activation and Modulation (DiNaMo TM) components.
DiNaMo components target key neural systems (including but not limited to systems related to sensory-, perceptual-, affective-, pain-, attention-, cognitive control, social- and self- processing) to optimally improve a participant's health. conditions: Psoriasis conditions: Atopic Dermatitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: SINGLE whoMasked: PARTICIPANT count: 120 type: ACTUAL name: CT-100-004-A name: CT-100-004-B measure: Change in Peak Pruritus Numerical Rating Scale measure: Change in Dermatology Life Quality Index measure: Change in Quality of Life symptoms measure: Time in App measure: Experience with Study App measure: Improved global rating of change measure: Frequency of Adverse Events measure: Severity of Adverse Events measure: Frequency of Serious Adverse Events measure: Severity of Serious Adverse Events sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Click Therapeutics city: New York state: New York zip: 10013 country: United States lat: 40.71427 lon: -74.00597 hasResults: False
nctId: NCT06275646 id: Adeel2 briefTitle: Comparison Of Outcome Of Different Layers in Hypospadias Surgery overallStatus: COMPLETED date: 2022-01-01 date: 2022-12-31 date: 2023-04-01 date: 2024-02-23 date: 2024-02-23 name: Children Hospital and Institute of Child Health, Lahore class: OTHER briefSummary: To compare the outcome of applying autologous platelet-rich plasma membrane layer and dartos fascial flap versus only dartos fascial flap in mid and distal penile hypospadias surgery. A total of 220 patients fulfilling the selection criteria were admitted after taking informed consent. Cases were randomly divided into groups A and B using a random generator of the Excel program. In group A, dartos flap and PRP sheet layer were applied and in group B, only a preputial dartos fascial flap was applied conditions: Hypospadias studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: randomized control trial primaryPurpose: TREATMENT masking: NONE count: 220 type: ACTUAL name: PRP layer name: dartos flap measure: wound infectiom measure: frequency of glans dehiscence measure: frequency of meatal stenosis sex: MALE minimumAge: 6 Months maximumAge: 12 Years stdAges: CHILD facility: The Children Hospital city: Lahore state: Punjab zip: 42000 country: Pakistan lat: 31.558 lon: 74.35071 hasResults: False
nctId: NCT06275633 id: H-18055648 briefTitle: Behavioural Profiling of Disease-related Cognitive and Motor Impairment in PD overallStatus: COMPLETED date: 2019-03-19 date: 2021-12-03 date: 2023-07-30 date: 2024-02-23 date: 2024-02-23 name: University Hospital Bispebjerg and Frederiksberg class: OTHER briefSummary: In this project, patients with Parkinson's Disease (PD) will be characterized by measuring cognitive and motor function and relation to effect of Levodopa.
Participants will be patients with Parkinson's Disease and healthy controls. It will be investigated if there is a difference between patients with a good measured Levodopa response and with a poor measured response. conditions: Parkinson Disease conditions: Medication conditions: UPDRS conditions: Motor Function conditions: Cognitive Impairment conditions: Depression conditions: Impulsive conditions: Levodopa studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: This is a prospective patient with Parkinson's Disease cohort. After acute levodopa challenge test patients with Parkinson's Disease are divided due to measured levodopa response and their self-rated medicine effect. primaryPurpose: DIAGNOSTIC masking: NONE maskingDescription: There will be a blinded assessment of videos of participants with Parkinson's Disease ON and OFF medication count: 68 type: ACTUAL name: Levodopa measure: Motor improvement measure: Cognitive function measure: Cognitive function measure: Depressive symptoms measure: Impulsivity sex: ALL minimumAge: 18 Years maximumAge: 90 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University Hospital Bispebjerg and Frederiksberg city: Copenhagen state: Region Hovedstaden zip: 2400 country: Denmark lat: 55.67594 lon: 12.56553 hasResults: False
nctId: NCT06275620 id: AGTC-RPGR-001 DAWN briefTitle: A Study Comparing Two Doses of AGTC-501 in Male Participants With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (DAWN) overallStatus: ENROLLING_BY_INVITATION date: 2023-11-14 date: 2025-07 date: 2029-08 date: 2024-02-23 date: 2024-03-21 name: Beacon Therapeutics class: INDUSTRY briefSummary: This Phase 2 study is a non-randomized, open-label, study of the safety of AGTC-501 in participants with XLRP who have previously been treated with a full-length AAV vector-based gene therapy targeting RPGR protein. conditions: X-Linked Retinitis Pigmentosa studyType: INTERVENTIONAL phases: PHASE2 allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: NONE count: 18 type: ESTIMATED name: AGTC-501 (high dose and standard corticosteroid regimen) name: AGTC-501 (low dose and standard corticosteroid regimen) name: AGTC-501 (high dose and modified corticosteroid regimen) measure: The primary safety outcome is the number and proportion of participants experiencing Grade 3 or higher local (ocular) or non-ocular treatment-emergent adverse events, including treatment-emergent serious adverse events (SAEs). measure: Change from baseline in mean sensitivity across the whole grid, as measured by MAIA microperimetry measure: Response, as measured by MAIA microperimetry, where response is defined as a greater than or equal to 7 dB visual sensitivity improvement from baseline in at least 7 loci. measure: Change from baseline in BCVA using Early-Treatment Diabetic Retinopathy Study (ETDRS) visual acuity measure: Change from baseline in LLVA using ETDRS visual acuity measure: Change from baseline in Ora-VNC mobility test score sex: MALE minimumAge: 12 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: University of Florida city: Jacksonville state: Florida zip: 32209 country: United States lat: 30.33218 lon: -81.65565 facility: Bascom Palmer Eye Institute city: Miami state: Florida zip: 33136 country: United States lat: 25.77427 lon: -80.19366 facility: Boston Children's Hospital city: Boston state: Massachusetts zip: 02115 country: United States lat: 42.35843 lon: -71.05977 facility: Cincinnati Eye Institute city: Cincinnati state: Ohio zip: 45242 country: United States lat: 39.12713 lon: -84.51435 facility: Cleveland Clinic city: Cleveland state: Ohio zip: 44195 country: United States lat: 41.4995 lon: -81.69541 facility: Casey Eye Institute city: Portland state: Oregon zip: 97239 country: United States lat: 45.52345 lon: -122.67621 facility: Retina Foundation of the Southwest city: Dallas state: Texas zip: 75231 country: United States lat: 32.78306 lon: -96.80667 hasResults: False
nctId: NCT06275607 id: FY23-24-93 briefTitle: Maladaptive Anger Treatment overallStatus: RECRUITING date: 2024-02-07 date: 2025-12-31 date: 2025-12-31 date: 2024-02-23 date: 2024-02-23 name: The University of Texas at San Antonio class: OTHER briefSummary: From a psychoevolutionary perspective, anger is a universal emotion that can serve the function of making us aware of wrongdoing and motivating us to undo/correct the wrongdoing. However, it is well recognized in clinical psychology that anger can be maladaptive, often causing distress and impairment in various areas of day-to-day life; untreated maladaptive anger has been found to raise the risk of certain physical health problems e.g., hypertension and coronary heart disease. At the very extreme, rage has been implicated in aggression and violence. Not surprisingly, there has been a widespread quest for anger treatments or what is popularly called "anger management". One treatment approach that has received increasing empirical support is Cognitive Behavioral Affective Therapy (CBAT), which has been applied to patients with chemical dependence and individuals with chronic pain. To extend this programmatic line of research, the proposed research aims to evaluate the efficacy of CBAT in reducing multiple (psychometric and self-monitored) measures of anger within a community sample. conditions: Anger conditions: Intermittent Explosive Disorder conditions: Emotional Distress conditions: Aggression conditions: Violence studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Parallel Assignment primaryPurpose: TREATMENT masking: NONE count: 100 type: ESTIMATED name: Cognitive Behavioral Affective Therapy name: Emotional Discussion measure: Anger Parameters Scale (APS) measure: Anger Parameters Scale (APS) measure: Anger Parameters Scale (APS) measure: Anger Expressions Scale (AES) measure: Anger Expressions Scale (AES) measure: Anger Expressions Scale (AES) measure: Self-Monitored Anger (Anger Log) measure: Self-Monitored Anger (Anger Log) sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The University of Texas at San Antonio status: RECRUITING city: San Antonio state: Texas zip: 78249 country: United States name: Ephrem Fernandez, Ph.D. role: CONTACT email: ephrem.fernandez@utsa.edu name: Brandon S Perez, M.S. role: CONTACT email: brandon.perez3@utsa.edu name: Ephrem Fernandez, Ph.D. role: PRINCIPAL_INVESTIGATOR name: Brandon S Perez, M.S. role: SUB_INVESTIGATOR lat: 29.42412 lon: -98.49363 hasResults: False
nctId: NCT06275594 id: YUMC2023-12-017 briefTitle: Trial Evaluating the Efficacy of Remimazolam in Endobronchial Ultrasound Guided Transbronchial Needle Aspiration acronym: REST overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-02-01 date: 2025-02-01 date: 2024-02-23 date: 2024-02-23 name: Yeungnam University Hospital class: OTHER briefSummary: Study to evaluate the efficacy and safety of remimazolam in patients undergoing endobronchial ultrasound-guided transbronchial needle aspiration
Secondary Outcome In patients undergoing EBUS-TBNA, compare the following aspects when administered with remimazolam in the experimental group versus Real world midazolam (Control Group 1) and On label midazolam (Control Group 2): Procedure start time, Time taken to achieve full alertness, Need for flumazenil administration, Total dose of fentanyl used, Scale of coughing/discomfort/convenience, Changes in vital signs, Complications related to the procedure. conditions: Midazolam conditions: Remimazolam studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 330 type: ESTIMATED name: Byfavo name: Midazolam measure: Procedural success during EBUS-TBNA (composite outcome) measure: Time to start of procedure after administration of the first dose of study medication measure: Time taken to achieve full alertness after the procedure measure: Requirement for flumazenil dosage during the procedure measure: Total fentanyl dose measure: Scale of coughing/discomfort/inconvenience measure: Changes in blood pressure measure: Changes of heart rate measure: Changes in respiration rate measure: Complications related to the procedure sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Yeungnam University Hospital city: Daegu state: Namgu zip: 42415 country: Korea, Republic of name: June Hong Ahn, M.D. PhD role: CONTACT phone: 821028562008 email: fireajh@gmail.com lat: 35.87028 lon: 128.59111 hasResults: False
nctId: NCT06275581 id: CR15_15 (EM-11-050055) briefTitle: Clinical Evaluation of the Performance of a Newly Developed Glass Ionomer Restorative for Posterior Restorations in an Adult Population overallStatus: TERMINATED date: 2017-06-14 date: 2021-03-24 date: 2021-10-01 date: 2024-02-23 date: 2024-02-23 name: Universidad Europea de Madrid class: OTHER name: 3M briefSummary: STUDY DESIGN Post market clinical follow-up; pilot study, prospective, controlled, randomized, split-mouth, blinded evaluation INTRODUCTION AND PURPOSE OF STUDY Continuous advancements in the field of glass ionomers have led to an increasing range of permanent indications, especially with regards to stress bearing Class II restorations. As a further development in the 3M glass ionomer category, Ketac Universal can be used for the abovementioned indication in a simplified procedure without the need for cavity conditioning or restoration coating. All products used in this study are CE marked thus can be used for routine clinical treatment.
After signing informed consent, test and control product were randomly assigned to the two study teeth (randomization letter). Restoration extension (e.g. mod) and reason for restoration placement (e.g. secondary caries, tooth fracture) were recorded in the CRF. Two teeth per subject were included. Each product was used strictly according to respective Instructions for Use without using the optional protective coating. Restorations were placed in combination with sectional matrix system (Palodent system) and according to best practice (especially with regards to moisture control). Finishing and polishing was done with the Sof-Lex system. Areas in close proximity to the pulp were covered with local application of a calcium hydroxide material in both study materials. Study teeth were excluded from study if pulp exposure had occurred or if only a repair restoration was required instead of a full Class II restoration.