hackint0sh/New-Dataset huggingface dataset:
Researchers will compare the intervention to usual care to see if it reduces opioid prescribing. conditions: Analgesics, Opioid conditions: Acute Pain conditions: Tooth Extraction conditions: Adolescent conditions: Acetaminophen conditions: Ibuprofen studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: Stepped wedge cluster randomized trial primaryPurpose: OTHER masking: DOUBLE maskingDescription: Blinding to the intervention is not possible in this study, as the intervention requires provider engagement. Provider participants and any clinic personnel will be blinded to the allocation sequence, and those not yet receiving the intervention will not be aware of the time at which they will have the intervention implemented. The study biostatistician will be aware of the allocation sequence.
At the beginning of each period, the study biostatistician will inform the research coordinator, project manager, academic detailing pharmacist, and PIs which cluster will be transitioning to the intervention condition next. This information will be used to facilitate scheduling academic detailing visits and coordinate blister pack and patient instructions material assembly. The clinic will be informed of their allocation during Visit 4 to facilitate scheduling academic detailing visits. whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 38159 type: ESTIMATED name: Multicomponent intervention name: Usual care measure: Odds of post-extraction opioid prescription to adolescent/young adults after tooth extraction measure: (Change in) intervention feasibility measure: (Change in) intervention appropriateness measure: (Change in) opioid prescribing feasibility measure: (Change in) opioid prescribing appropriateness measure: Self-reported pain measure: Self-reported pain interference measure: Self-reported pain satisfaction sex: ALL minimumAge: 12 Years maximumAge: 25 Years stdAges: CHILD stdAges: ADULT facility: University of Kentucky city: Lexington state: Kentucky zip: 40536 country: United States name: Jennifer Dolly Prothro, MPH role: CONTACT email: jenniferdolly@uky.edu name: Enif Dominguez, DDS role: SUB_INVESTIGATOR name: Patricia R Freeman, PhD role: SUB_INVESTIGATOR name: Hannah K Knudsen, PhD role: SUB_INVESTIGATOR name: Craig S Miller, DDS role: SUB_INVESTIGATOR name: Sharon L Walsh, PhD role: SUB_INVESTIGATOR name: Philip M Westgate, PhD role: SUB_INVESTIGATOR lat: 37.98869 lon: -84.47772 hasResults: False
nctId: NCT06275178 id: ZRJY2021-BJ08-02-04 briefTitle: Medical Thoracoscopy for Diagnosing Unexplained Pleural Effusion: a National Multicenter Retrospective Study overallStatus: NOT_YET_RECRUITING date: 2024-03-20 date: 2024-12-24 date: 2024-12-31 date: 2024-02-23 date: 2024-02-23 name: China-Japan Friendship Hospital class: OTHER briefSummary: This study is a national multicenter retrospective study. Patients with unexplained pleural effusion who underwent thoracoscopic or video-assisted thoracoscopic biopsy for patients in recent 10 years were retrospectively collected from multiple centers to understand the proportion and final etiological composition of pleural effusion in China. conditions: Pleural Effusion conditions: Pleural Effusion, Malignant conditions: Fibrinous Pleuritis studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: RETROSPECTIVE count: 5000 type: ESTIMATED name: Medical thoracoscopy measure: The proportion of fibrinous pleurisy in Chinese population sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06275165 id: 202301754B0 briefTitle: The Effects of Acupressure on Improving Postoperative Gastrointestinal Symptom Distress in Esophageal Cancer Patients overallStatus: RECRUITING date: 2024-03-27 date: 2025-07-18 date: 2025-07-18 date: 2024-02-23 date: 2024-03-29 name: CHEN, CHIA-CHEN class: OTHER briefSummary: This study is a quasi-experimental design clinical trial with the primary objective of comparing the health status of patients with esophageal cancer. Participants were divided into an experimental group and a control group. Patients in the experimental group received routine care and acupressure for 5 consecutive days starting from the day after entering the ward after esophageal cancer surgery, in the control group, participants received routine care, and Participants were assessed on the Gastrointestinal Symptom Distress Scale at the end of the intervention. The aim of this study was to verify the effectiveness of acupressure in improving of gastrointestinal symptoms distress after esophageal cancer surgery. conditions: Esophageal Cancer conditions: Gastrointestinal Dysfunction studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Participants were divided into an experimental group and a control group. experimental group: received acupressure for 5 days in addition to regular care.
control group: received regular postoperative care. primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: acupressure measure: Change from Baseline in gastrointestinal symptom distress Scale at study day 5(end day) sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Chang Gung Memotial Hospital status: RECRUITING city: Taoyuan country: Taiwan name: Chia-Chen Chen role: CONTACT phone: +886-3-3281200 phoneExt: 3005 email: mymychen73@gmail.com lat: 24.95233 lon: 121.20193 hasResults: False
nctId: NCT06275152 id: HDRIC-01 briefTitle: The Protective Effect of Remote Ischemic Conditioning on Residual Renal Function in Hemodialysis Patients (RIC-HD) acronym: RIC-HD overallStatus: ENROLLING_BY_INVITATION date: 2024-02-20 date: 2026-01-19 date: 2026-01-19 date: 2024-02-23 date: 2024-02-26 name: Yuanjun Yang class: OTHER briefSummary: Hemodialysis (HD) is the main renal replacement therapy for patients with end-stage renal disease. However, factors such as hemodynamic instability can lead to gradual loss of residual renal function (RRF) in HD patients. The loss of RRF not only affects the adequacy of dialysis and complications control but also impacts the patients' quality of life and survival. Unfortunately, there are currently no effective methods to protect RRF. The purpose of this study is to validate the protective effect of remote ischemic conditioning (RIC) on RRF in HD patients. This will provide evidence for the application of RIC in protecting RRF in HD patients. conditions: End-stage Renal Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: randomized controlled pilot study primaryPurpose: PREVENTION masking: QUADRUPLE maskingDescription: Only Research Assistant will be unblinded. Participant, clinical team, PI, etc. will all be blinded to the randomization group. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Remote ischemic conditioning name: Sham Remote Ischemic Conditioning measure: time to anuria measure: residual renal function (RRF) measure: Change in the renal cerebral oxygen saturation measure: serum creatinine measure: serum urea nitrogen measure: C-reactive protein (CRP) measure: Interleukin-6 measure: TFF3 measure: KIM-1 measure: IP-10 measure: hemoglobin measure: systolic pressure measure: diastolic pressure sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Chinese PLA General Hospital city: Beijing state: Beijing zip: 100853 country: China lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06275139 id: 2023-GSP-GG-9 briefTitle: Integrated Assessment of Cervicocerebral Vessels to Improve the Brain Injury for CAGB Patients (IACV Study) overallStatus: RECRUITING date: 2023-01-01 date: 2024-06-30 date: 2024-12-31 date: 2024-02-23 date: 2024-02-23 name: China National Center for Cardiovascular Diseases class: OTHER_GOV briefSummary: The goal of this study is to establish a prospective study to focus on the high-risk stroke population who require coronary artery bypass graft surgery. It will divide the eligible patients into 1:1 group by simple randomization method. The control group adopt the traditional diagnosis and treatment mode, and only head CT plain scan and carotid artery ultrasound shall be performed. If necessary, relevant disciplines would be consulted but no integrated assessment of cervicocerebral vessels be arranged. The final treatment plan would be decided by the surgeon alone. The experimental group adopt the multidisciplinary collaboration and integrated evaluation mode. In addition to routine diagnosis and treatment as above-mentioned, integrated assessment of cervicocerebral vessels shall be performed, including transcranial color-coded doppler, cerebral perfusion with multislice CT, and cognitive function assessment. Based on the above results, surgical plans will be formulated jointly by multiple disciplines including neurologists, vascular surgeons, ICU physicians and cardiac surgeons. Researchers will compare the two groups to investigate whether integrated assessment of cervicocerebral vessels can reduce the incidence of brain injury compared with conventional diagnosis and treatment mode. conditions: Coronary Disease conditions: Coronary Artery Bypass conditions: Strokes Thrombotic studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Integrated assessment of cervicocerebral vessels shall be performed, including transcranial color-coded doppler, cerebral perfusion with multislice CT, and cognitive function assessment. primaryPurpose: PREVENTION masking: NONE count: 348 type: ESTIMATED name: Integrated Assessment of Cervicocerebral Vessels measure: The incidence of neurological complications measure: The incidence of major adverse cardiac events measure: Neurological scale scores sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fuwai Hospital; National Cardiovascular Center; Peking Union Medical College & Chinese Academy of Medical Sciences status: RECRUITING city: Beijing state: Beijing zip: 100037 country: China name: Huanmei Liu, MD role: CONTACT email: ncrc@fuwai.com lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06275126 id: 23-08026433 id: R01CA256877-01A1 type: NIH link: https://reporter.nih.gov/quickSearch/R01CA256877-01A1 briefTitle: Optimizing Surgical Decisions in Young Adults With Breast Cancer acronym: CONSYDER overallStatus: RECRUITING date: 2024-03-13 date: 2026-09 date: 2027-05 date: 2024-02-23 date: 2024-04-10 name: Weill Medical College of Cornell University class: OTHER name: National Institutes of Health (NIH) name: National Cancer Institute (NCI) briefSummary: The goal of this study is to understand and improve the breast surgical decision-making process for young women newly diagnosed with breast cancer. As part of this study, the investigators will evaluate the impact and use a web-based tool called CONSYDER that is designed to provide useful information to young breast cancer patients. It is also meant to improve communication between young women and their surgeons with the purpose of helping patients make appropriate surgical decisions.
nctId: NCT06275113 id: K25 briefTitle: BRING-UP Prevention overallStatus: RECRUITING date: 2023-09-15 date: 2026-06-30 date: 2026-06-30 date: 2024-02-23 date: 2024-02-23 name: Heart Care Foundation class: OTHER briefSummary: The aim of this observational study is to assess in patients with a documented athero-thrombotic event: coronary artery disease (CAD), cerebrovascular disease (CVD), peripheral artery disease (PAD):
nctId: NCT06275100 id: HUTH briefTitle: PREhabilitation in Patients Awaiting Acute Inpatient Cardiac SurgEry acronym: (PREP-ACE) overallStatus: RECRUITING date: 2024-04-03 date: 2024-12 date: 2025-06 date: 2024-02-23 date: 2024-04-09 name: University of Hull class: OTHER briefSummary: This is a single centre, single arm pilot feasibility study to determine the feasibility and practicality of prehabilitation in acute inpatients waiting for cardiac surgery. We will be looking into participant eligibility, acceptability, recruitment rates, completion rates and barriers to implementing a prehabilitation programme. Secondary outcomes include safety (incidence of adverse events directly related to the study), improvement in 6 minutes walk test (6MWT), hand grip strength, quality of life, and spirometry. At the end of the trial, we will be seeking the feedback of the participants to help us improve the design further. conditions: Cardiac Disease conditions: Aortic Valve Disease conditions: Coronary Artery Disease conditions: Endocarditis conditions: Valve Heart Disease studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Single arm pilot feasibility study in acute inpatients waiting for cardiac surgery. Intervention is a prehabilitation program primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 20 type: ESTIMATED name: Prehabilitation measure: Feasibility of prehabilitation in acute inpatients waiting for cardiac surgery measure: Efficacy of prehabilitation measure: Efficacy of prehabilitation measure: Efficacy of prehabilitation measure: Efficacy of prehabilitation measure: Efficacy of prehabilitation measure: Complication rate measure: Safety of Prehabilitation in acute inpatients waiting for surgery sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hull University Teaching Hospital status: RECRUITING city: Hull zip: HU1 3DR country: United Kingdom lat: 53.7446 lon: -0.33525 typeAbbrev: Prot hasProtocol: True hasSap: False hasIcf: False label: Study Protocol date: 2023-11-06 uploadDate: 2024-02-15T17:59 filename: Prot_000.pdf size: 146015 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2023-11-06 uploadDate: 2024-02-15T18:01 filename: ICF_001.pdf size: 107547 hasResults: False
nctId: NCT06275087 id: situm1phd briefTitle: Differences in Speed of Recovery From Anesthesia for Intraoral Surgery acronym: PSIOS overallStatus: RECRUITING date: 2024-04-10 date: 2026-03 date: 2026-07 date: 2024-02-23 date: 2024-04-22 name: Clinical Hospital Centre Zagreb class: OTHER briefSummary: The goal of this clinical trial is to compare two groups of patients going in general anesthesia for intraoral surgery, the first group TIVA with propofol and the second group inhalational with sevoflurane. The main questions it aims to answer are to asses speed and quality of recovery from general anesthesia.
Participants will fill out a questionnaire to evaluate the quality of recovery from anesthesia using the QoR-40 1h, 24h, and 30 days after waking up from anesthesia in comparison to the results of the same questionnaire before surgery. Also, the investigators will perform a hand grip and bite strength test on the patients after waking up from anesthesia in the operating room, after 1 hour in the recovery room, and after 24 hours compared to preoperative values.
The investigators will compare TIVA and Volatile groups to see if there are any differences in recovery seed, muscle strength recovery, postoperative nausea and vomiting, and shivering between groups. conditions: Intraoral Tumor studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 42 type: ESTIMATED name: Propofol name: Sevoflurane measure: "Quality of recovery from anesthesia" QoR-40 questionnaire measure: bite strength and hand grip strength measure: Postoperative nausea and vomiting measure: Postoperative shivering sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University Hospital Centre Zagreb status: RECRUITING city: Zagreb zip: 10000 country: Croatia name: Ivan Šitum role: CONTACT phone: 0915143620 email: ivsitum@gmail.com name: Ivan Šitum role: PRINCIPAL_INVESTIGATOR lat: 45.81444 lon: 15.97798 hasResults: False
nctId: NCT06275074 id: 23-007716 briefTitle: Dry Needling and Therapeutic Exercise on Sleep in Individuals With Chronic Neck Pain and Sleep Disturbance overallStatus: RECRUITING date: 2024-03-14 date: 2024-09-01 date: 2025-03-01 date: 2024-02-23 date: 2024-04-05 name: Mayo Clinic class: OTHER briefSummary: Feasibility study investigating the effects of dry needling on individuals with chronic neck pain and sleep disturbance. conditions: Neck Pain conditions: Sleep Disturbance studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: SINGLE maskingDescription: Outcome assessors will be blinded to group assignment of participants. whoMasked: OUTCOMES_ASSESSOR count: 28 type: ESTIMATED name: Dry Needling name: Therapeutic Exercise measure: Participant retention rate measure: Participant intervention adherence measure: Number of adverse responses to treatment measure: Sleep Duration measure: Sleep Quality measure: Disability Level measure: Pain Level sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mayo Clinic - Motion Analysis Lab status: RECRUITING city: Rochester state: Minnesota zip: 55905 country: United States name: Ray Lunasin role: CONTACT phone: 507-538-0839 email: lunasin.ray@mayo.edu lat: 44.02163 lon: -92.4699 hasResults: False
nctId: NCT06275061 id: KY-2020-021 briefTitle: Chinese Obesity and MEtabolic Surgery Database (COMES Database) acronym: COMES overallStatus: RECRUITING date: 2020-05-01 date: 2030-12-31 date: 2040-12-31 date: 2024-02-23 date: 2024-02-23 name: Jinan University Guangzhou class: OTHER name: Chinese Obesity and Metabolic Surgery Collaborative briefSummary: The purpose of the Chinese Obesity and MEtabolic Surgery Database (COMES Database) is to collect data and examine the long-term effects of metabolic and bariatric surgery on obesity and metabolic disorders in the Chinese population. conditions: Obesity conditions: Metabolic Surgery conditions: Bariatric Surgery conditions: Weight Loss studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 1000000 type: ESTIMATED name: Metabolic and Bariatric Surgery measure: Excess weight loss effect of metabolic and bariatric surgery after 1 year measure: Excess weight loss effect of metabolic and bariatric surgery in long-term follow-ups measure: Excess weight loss effect of metabolic and bariatric surgery in long-term follow-ups measure: Excess weight loss effect of metabolic and bariatric surgery in long-term follow-ups measure: Glycemic control effect of metabolic and bariatric surgery after 1 year measure: Glycemic control effect of metabolic and bariatric surgery in long-term follow-ups measure: Glycemic control effect of metabolic and bariatric surgery in long-term follow-ups measure: Glycemic control effect of metabolic and bariatric surgery in long-term follow-ups measure: Glycemic control effect of metabolic and bariatric surgery after 1 year measure: Glycemic control effect of metabolic and bariatric surgery in long-term follow-ups measure: Glycemic control effect of metabolic and bariatric surgery in long-term follow-ups measure: Glycemic control effect of metabolic and bariatric surgery in long-term follow-ups measure: Glycemic control effect of metabolic and bariatric surgery after 1 year measure: Glycemic control effect of metabolic and bariatric surgery in long-term follow-ups measure: Glycemic control effect of metabolic and bariatric surgery in long-term follow-ups measure: Glycemic control effect of metabolic and bariatric surgery in long-term follow-ups measure: Glycemic control effect of metabolic and bariatric surgery after 1 year measure: Glycemic control effect of metabolic and bariatric surgery in long-term follow-ups measure: Glycemic control effect of metabolic and bariatric surgery in long-term follow-ups measure: Glycemic control effect of metabolic and bariatric surgery in long-term follow-ups measure: Adverse events rate of metabolic and bariatric surgery sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: The First Affiliated Hospital of Jinan University status: RECRUITING city: Guangzhou state: Guangdong zip: 510630 country: China name: Wah Yang, MD role: CONTACT phone: +8615920373823 email: yangwah@qq.com lat: 23.11667 lon: 113.25 hasResults: False
nctId: NCT06275048 id: STUDY00006302 briefTitle: The Influence of Oral Contraceptives During Disuse overallStatus: RECRUITING date: 2024-01-26 date: 2024-12 date: 2025-05 date: 2024-02-23 date: 2024-02-23 name: University of Central Florida class: OTHER briefSummary: Studies across various sports and physical activities have consistently shown that females incur more injuries compared to their male counterparts, but the underlying reasons for this disparity remain poorly understood. While differences in hormone levels between males and females have been speculated to play a role, very little rigorous research has been conducted to directly examine potential connections between sex hormones and injury risk. Specifically, females have been shown to be at greater risk for hand and wrist injuries. The higher injury incidence begins at puberty and persists across the lifespan, suggesting a link to hormonal factors. However, significant gaps remain in understanding the relationships between the menstrual cycle, exogenous hormones from birth control, and risk factors for sports-related injury in females. The purpose of this study is to examine changes in muscle strength and neuromuscular activation among females using monophasic oral contraceptives, females not using oral contraceptives, and males during one week of wrist/hand immobilization. conditions: Oral Contraceptives conditions: Rehabilitation conditions: Menstrual Cycle conditions: Physical Therapy studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: BASIC_SCIENCE masking: NONE count: 60 type: ESTIMATED name: Wrist/hand immobilization measure: Grip Strength measure: Muscle activation sex: ALL minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: University of Central Florida status: RECRUITING city: Orlando state: Florida zip: 32816 country: United States name: Matt S Stock, Ph.D. role: CONTACT phone: 407-823-0364 email: matt.stock@ucf.edu name: Matt S Stock, Ph.D. role: PRINCIPAL_INVESTIGATOR lat: 28.53834 lon: -81.37924 hasResults: False