hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06260826 id: 3977/QĐ-HVQY briefTitle: CPAP on Oxygenation and Pulmonary Function in Elderly Patients After Major Open Abdominal Surgery acronym: CPAP overallStatus: COMPLETED date: 2021-12-01 date: 2022-08-20 date: 2022-08-30 date: 2024-02-15 date: 2024-02-15 name: Nguyen Dang Thu class: OTHER briefSummary: Postoperative continuous positive airway pressure (CPAP) can improve lung function. The risk of pulmonary complications is high after major abdominal surgery but may be reduced by prophylactic postoperative noninvasive ventilation using CPAP. This study compared the effects of auto-CPAP via a nasal mask (JPAP) and constant-CPAP via a facial mask (O2-Max Trio) on oxygenation and pulmonary function in elderly patients after major open abdominal surgery. conditions: Continuous Positive Airway Pressure conditions: Pulmonary Function conditions: Older People studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Patients were randomly assigned in a 1:1 ratio to either the O2-Max Trio or JPAP group through a computer-generated randomization list . primaryPurpose: TREATMENT masking: NONE maskingDescription: the treatment allocation was unblinded to both the patient and the staffs count: 60 type: ACTUAL name: Auto CPAP via nasal mask (JPAP machine) name: Constant CPAP via facial mask (O2-Max Trio system) measure: The oxygenation-PaO2/FiO2 measure: The forced vital capacity (FVC) measure: The forced expiratory volume in the first second-FEV1 measure: The FEV1/FVC ratio measure: The peak expiratory flow-PEF sex: ALL minimumAge: 60 Years stdAges: ADULT stdAges: OLDER_ADULT facility: VietXo Friendship Hospital city: Hanoi zip: 12108 country: Vietnam lat: 21.0245 lon: 105.84117 hasResults: False
nctId: NCT06260813 id: S66277 briefTitle: Biomechanical and Morphological Characterization of PTTD acronym: PTTD overallStatus: RECRUITING date: 2022-08-22 date: 2028-08-01 date: 2028-08-01 date: 2024-02-15 date: 2024-02-15 name: Universitaire Ziekenhuizen KU Leuven class: OTHER briefSummary: Posterior tibial tendon dysfunction (PTTD) is a progressive condition of the tendon of the tibialis posterior muscle with symptoms of tendinopathy or even rupture. Functionally, it is associated with the inability to lock the mid foot and thus manifests itself as a main contributor to adult acquired flatfoot deformity.
Concerning treatment, clinical decision making is currently based on a classification integrating various parameters as pain, flexibility of the foot joints, the condition of the posterior tibial tendon assessed through ultrasound imaging and radiographic assessment of arthritic changes. Surprisingly, this classification does not consider any morphologic characteristics (the shape of a bone or joint) or functional, biomechanical characteristics of the foot and ankle, i.e. based on kinematics (e.g. range of motion) and/or kinetics (center of pressure, angular velocity, moment, power absorption and power generation of a joint).
Detailed biomechanical characteristics of the foot and ankle can be reliably collected by instrumented gait analysis wherein a 3D camera system is combined with a force plate and plantar pressure platform. Kinematic studies in the field of PTTD typically considered the foot as a structure consisting of three segments: hind foot, forefoot and hallux. Consequently, the mid foot segment (the Chopart and Lisfranc joints) has been neglected, although it is this segment that is particularly affected in PTTD patients.
The aim of this research is to overcome the limitations of the current classification system and treatment of PTTD patients, by complementing the current standard-of-care clinical assessment with better insight in the pathologic changes that occur in PTTD patients. conditions: Posterior Tibial Tendon Dysfunction studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Prospective interventional study that includes PTTD patients (PTTD I, II and III) and a healthy control group. primaryPurpose: DIAGNOSTIC masking: SINGLE maskingDescription: PTTD patients (PTTD I, II and III) and a healthy control group. whoMasked: PARTICIPANT count: 100 type: ESTIMATED name: Radiography name: Ultrasound name: MRI name: CT-scan name: Gait analysis measure: Kinematic characteristics during Gait analysis measure: Center of pressure during Gait analysis measure: Angular velocity during Gait analysis measure: Moment during Gait analysis measure: Power absorption during Gait analysis measure: Power generation during Gait analysis measure: Bone morphology measure: American Orthopaedic Foot & Ankle Society (AOFAS) score measure: European Foot and Ankle Society (EFAS) score measure: 36-item Short Form Health Survey (SF36) measure: Visual Analogue Scale (VAS) pain measure: Visual Analogue Scale (VAS) satisfaction sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: UZ Leuven status: RECRUITING city: Leuven state: Vlaams-Brabant zip: 3000 country: Belgium name: Sander Wuite role: CONTACT phone: +32 16 33 83 29 email: sander.wuite@uzleuven.be name: Kevin Deschamps role: CONTACT phone: +32 16 33 88 27 email: kevin.deschamps@uzleuven.be lat: 50.87959 lon: 4.70093 hasResults: False
nctId: NCT06260800 id: PI 23-3405 briefTitle: Spanish Version of Credibility and Expectancy Questionnaire in Patients With Musculoskeletal Injuries overallStatus: RECRUITING date: 2024-01-08 date: 2024-07-01 date: 2024-11-30 date: 2024-02-15 date: 2024-02-15 name: University of Valladolid class: OTHER briefSummary: Physiotherapy treatment of musculoskeletal injuries should be performed following the main clinical guidelines of person-centered care. Patients' perception of the abilities and facilities provided by physiotherapists boost a convenient therapeutic relationship. This relation is linked with more satisfaction and adherence during the treatment, as well as credibility and expectancy of the patient related to the treatment. Thus, Credibility and Expectancy questionnaire is normally used to assess that point. CEQ presents good psychometric properties when used in Physisiotherapy interventions, but there is not a spanish version of this questionaire. conditions: Validation Study studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 60 type: ESTIMATED name: Validation CEQ measure: Content validity measure: Construct validity measure: Reliability measure: Criterion validity sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Silvia Lahuerta Martín status: RECRUITING city: Soria zip: 42004 country: Spain lat: 41.76401 lon: -2.46883 hasResults: False
nctId: NCT06260787 id: OBGY-202401.01 briefTitle: Clinical Profiles And In Vitro Fertilization Success overallStatus: COMPLETED date: 2023-01-01 date: 2023-03-31 date: 2023-12-31 date: 2024-02-15 date: 2024-02-15 name: Universitas Padjadjaran class: OTHER briefSummary: This research was carried out to determine if the IVF patients' clinical profile were connected with how successful in their getting pregnant. This was a cross-sectional study which recruited all patients, performed at a major fertility clinic in Indonesia. Our data collection period spanned between January 2017 and December 2021. conditions: in Vitro Fertilisation studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: CROSS_SECTIONAL count: 223 type: ACTUAL name: In Vitro Fertilisation measure: Pregnancy rate sex: FEMALE stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran city: Bandung state: Jawa Barat zip: 40161 country: Indonesia lat: -6.92222 lon: 107.60694 hasResults: False
nctId: NCT06260774 id: TTX-MC138-002 briefTitle: Study of TTX-MC138 in Subjects With Advanced Solid Tumors overallStatus: NOT_YET_RECRUITING date: 2024-05-30 date: 2026-02-01 date: 2027-02-01 date: 2024-02-15 date: 2024-04-09 name: TransCode Therapeutics class: INDUSTRY briefSummary: A Phase 1/2 Multicenter, Open-Label, Dose-Escalation and Expansion Study of TTX MC138 in Subjects with Advanced Solid Tumors conditions: Advanced Solid Tumor studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: Dose Escalation Study Design primaryPurpose: TREATMENT masking: NONE count: 20 type: ESTIMATED name: TTX-MC138 measure: Dose Escalation - Adverse Events measure: Dose Escalation - Overall Response Rate (ORR) sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06260761 id: Dh3108103/64 briefTitle: MIPO Versus Conventional Approach in Volar Locking Plate for Close Fractures Distal End Radius Under WALANT overallStatus: COMPLETED date: 2021-10-05 date: 2023-02-05 date: 2023-02-05 date: 2024-02-15 date: 2024-02-15 name: Police General Hospital, Thailand class: OTHER briefSummary: The goal of this clinical trial is to compare the Minimally Invasive Plate Osteosynthesis (MIPO) approach with conventional methods in volar locking plate treatment for distal end radius fractures under the Wide Awake Local Anesthesia No Tourniquet (WALANT) technique. The main question it aims to answer is: Does the MIPO approach provide better pain control than the conventional approach of volar locking plate fixation in distal radius fractures under WALANT? Participants will be requested to record their pain on the Visual Analog Scale (VAS), assess their functional scores, and undergo postoperative radiographic evaluations. Researchers will compare the MIPO group and the conventional group to determine the postoperative pain VAS scores, shedding light on the comparative effectiveness of the two approaches. conditions: Radius; Fracture, Lower or Distal End studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: prospective, parallel group, assessor-blinded, randomized controlled trial. randomized with computer generator number and use block-of-four. primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: The data collector, an orthopedic resident unaware of the surgical technique used, obtained information after operation. whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 68 type: ACTUAL name: MIPO name: Conventional measure: Pain Visual analogue scale measure: Quick Disabilities of the Arm, Shoulder and Hand measure: Grip strength measure: Pinch strength measure: Range of motion measure: Aesthetics measure: Satisfy measure: Volar tile measure: ulnar variance measure: radial inclination measure: operation time measure: skin incision measure: morphine IV use measure: complication sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Police general hospital city: Pathum Wan state: Bangkok zip: 10330 country: Thailand lat: 13.73649 lon: 100.5239 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2021-10-05 uploadDate: 2024-02-04T06:00 filename: Prot_SAP_000.pdf size: 1309374 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2021-10-05 uploadDate: 2024-02-04T06:05 filename: ICF_001.pdf size: 80882 hasResults: False
nctId: NCT06260748 id: LBI-CDCA-001 id: 2023-505759-29-00 type: OTHER domain: EU Clinical Trials Register briefTitle: A Study of Chenodeoxycholic Acid (CDCA) in Newly Diagnosed Participants With Cerebrotendinous Xanthomatosis (CTX) overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-11-30 date: 2025-12-31 date: 2024-02-15 date: 2024-02-15 name: Leadiant Biosciences, Inc. class: INDUSTRY briefSummary: This study is designed to demonstrate the beneficial effect of CDCA in the treatment of CTX-associated diarrhea in approximately 10 participants aged 2-75 years old with newly diagnosed CTX or suspected CTX who have never received treatment with CDCA. conditions: Cerebrotendinous Xanthomatoses studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 10 type: ESTIMATED name: Chenodeoxycholic acid name: Chenodeoxycholic acid Placebo measure: Change from baseline at Week 4 in average number of stools with a BSS score of 6 or 7 per day measure: Change in plasma cholestanol levels from baseline to Week 12 measure: Change in urine and/or plasma bile alcohol levels from baseline to Week 12 measure: Incidence of, severity/intensity of, and relationship to study drug of AEs measure: Incidence of, severity/intensity of, and relationship to study drug of SAEs measure: Incidence of, severity/intensity of AESIs measure: Incidence of, severity/intensity of, and changes in laboratory values measure: Incidence of, severity/intensity of, and changes in physical examination measure: Incidence of, severity/intensity of, and changes in vital signs measure: Number of participants with discontinuations due to AEs sex: ALL minimumAge: 2 Years maximumAge: 75 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06260735 id: HS25897 (H2023:073) id: URGP#51472 type: OTHER_GRANT domain: University of Manitoba id: RGPIN-2015-05703 type: OTHER_GRANT domain: NSERC briefTitle: Non-invasive Spinal Cord Stimulation After Spinal Cord Injury acronym: SCI-ES-WALK overallStatus: RECRUITING date: 2023-06-15 date: 2024-08-15 date: 2024-11-15 date: 2024-02-15 date: 2024-02-15 name: University of Manitoba class: OTHER briefSummary: Spinal cord injury (SCI) is a central nervous system injury that often leads to motor dysfunction. Non-invasive electrical stimulation of the spinal cord has been recognized as a potential method of reactivating lost spinal neural networks to improve motor recovery and exercise response after SCI. Trans-spinal electrical stimulation (ts-ES) has been found to increase functional gains in people after SCI when applied in combination with other motor training protocols.
This project aims to evaluate the effects of non-invasive lumbar spinal cord electrical stimulation on the motor function of trunk and lower limbs in people with SCI after augmenting their locomotor training (treadmill stepping) with step-cycle-based electrical peripheral neural stimulation methods. conditions: Spinal Cord Injuries conditions: Spinal Cord Diseases studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 10 type: ESTIMATED name: Trans-spinal electrical stimulation name: Electrical muscle activation name: Treadmill walking measure: Neurophysiological markers or stepping measure: Electromyography (EMG) of ankle extensor muscles measure: Metabolic function testing measure: 6 Min Walk Test measure: SCIM-Spinal Cord Independence Measure- Mobility scores measure: Autonomic scores measure: Rate or Perceived Exertion (RPE) of Submaximal VO2 testing sex: ALL minimumAge: 20 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Manitoba status: RECRUITING city: Winnipeg state: Manitoba zip: R3E 0W2 country: Canada name: Katinka Stecina role: CONTACT phone: 204-789-3761 email: katinka.stecina@umanitoba.ca lat: 49.8844 lon: -97.14704 hasResults: False
nctId: NCT06260696 id: DAS-7626 id: U1111-1282-5512 type: OTHER domain: World Health Organization (WHO) briefTitle: Assessing Health-Related Quality of Life and Willingness to Pay for Weight Management in Asia-Pacific by Gender acronym: ASPECT - APAC overallStatus: COMPLETED date: 2023-08-10 date: 2023-10-05 date: 2023-10-05 date: 2024-02-15 date: 2024-02-15 name: Novo Nordisk A/S class: INDUSTRY briefSummary: The purpose of this survey is to collect information for scientific research and to identify the impact of overweight and obesity on health-related quality of life. conditions: Overweight conditions: Obesity studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 3000 type: ACTUAL name: No treatment is given measure: Score on IWQOL-Lite validated sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Novo Nordisk Investigational Site city: Dubai country: United Arab Emirates lat: 25.0657 lon: 55.17128 hasResults: False
nctId: NCT06260683 id: OSU-22240 id: NCI-2023-04102 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: R01DA057327 type: NIH link: https://reporter.nih.gov/quickSearch/R01DA057327 briefTitle: A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior overallStatus: NOT_YET_RECRUITING date: 2024-04-29 date: 2027-04-29 date: 2027-04-29 date: 2024-02-15 date: 2024-04-03 name: Ohio State University Comprehensive Cancer Center class: OTHER name: National Institute on Drug Abuse (NIDA) briefSummary: This clinical trial compares the use of tobacco flavored electronic cigarettes (ECs) to non-tobacco flavored ECs on smoking behavior in current cigarette smokers to use of nicotine replacement therapy (patches and lozenges). ECs may reduce cigarette craving and withdrawal symptoms, increase motivation and confidence to stop cigarette smoking, and decrease cigarette smoking and dependence. By comparing participants' preferred flavor ECs (PEC) to tobacco flavor ECs (TEC) to NRT, researchers hope to determine the effect of EC flavors on appeal and use, and learn how ECs affect smoking behaviors and health. conditions: Cigarette Smoking-Related Carcinoma studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 1500 type: ESTIMATED name: Nicotine Replacement name: Questionnaire Administration name: Vaping name: Vaping measure: Biochemically verified 7-day point prevalence abstinence from cigarettes measure: Switching rate measure: Cigarettes smoked per day measure: Change in nicotine dependence measure: Changes in cigarette craving and nicotine withdrawal measure: Number of days used measure: Product appeal measure: Continued purchase and use of ECs sex: ALL minimumAge: 21 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ohio State University Comprehensive Cancer Center city: Columbus state: Ohio zip: 43210 country: United States name: Theodore L. Wagener, PhD role: CONTACT email: Theodore.Wagener@osumc.edu name: Theodore L. Wagener, PhD role: PRINCIPAL_INVESTIGATOR lat: 39.96118 lon: -82.99879 hasResults: False
nctId: NCT06260670 id: CP0004 briefTitle: FLOW EVAL-AF: FLOW Mapping Electrogram VALidation in Patients With Persistent Atrial Fibrillation acronym: FLOW EVAL-AF overallStatus: COMPLETED date: 2022-09-01 date: 2022-10-28 date: 2022-10-28 date: 2024-02-15 date: 2024-02-15 name: Ablacon, Inc. class: INDUSTRY briefSummary: FLOW EVAL-AF is a prospective, observational, single center pilot trial. The FLOW EVAL-AF trial is designed to identify driver sources in patients with persistent or longstanding persistent AF using EGF mapping and describe the activation patterns observed from concomitant high density mapping of those regions. conditions: Persistent Atrial Fibrillation conditions: Longstanding Persistent Atrial Fibrillation conditions: Atrial Fibrillation, Persistent conditions: Arrhythmias, Cardiac studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 10 type: ACTUAL name: Electrographic Flow™ Mapping using Ablamap® Software and FIRMap™ Catheter measure: Descriptive correlation of electrogram patterns sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Herz-und Diabeteszentrum NRW (Clinic of Ruhr University of Bochum) city: Bad Oeynhausen state: North Rhine-Westphalia zip: 32545 country: Germany lat: 52.20699 lon: 8.80365 hasResults: False
nctId: NCT06260657 id: 2021PI124 briefTitle: Search for Olfactory Cells Within the Fetal Ethmoid Epithelium acronym: COEF overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2025-10 date: 2025-10 date: 2024-02-15 date: 2024-02-15 name: Central Hospital, Nancy, France class: OTHER briefSummary: The recent rhinological functional approach known as "Evo-Devo" leads us to consider the nose not as a single organ, but as the construction of a specifically olfactory organ within which functional respiratory structures have developed over the course of species evolution in the same way they develop during human embryogenesis.
The hypothesis of this study posits that, during the embryological development of the ethmoid bone, it would initially be covered with olfactory mucosa, which would gradually diminish as the lateral masses of the ethmoid formed, eventually persisting exclusively within the olfactory clefts of the ethmoid by the conclusion of the first trimester (end of organogenesis). Besides their fundamental interest, the results of this study could help understand the still unknown pathogenesis of nasal polyposis, a chronic anosmic disease with a prevalence of 2 to 4% in the French and European population.
This study requires a series of ethmoidal samples from human fetuses at various ages between 7 and 15 weeks of gestational age. Specific immunohistological labeling techniques under standard optical microscopy will be used to search for and quantify olfactory nerve cells within the fetal ethmoidal mucosa. conditions: Fetal Ethmoidal Mucosa studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 20 type: ESTIMATED name: Histological analysis on fetal ethmoids measure: Immunohistological positive signal of primary olfactive neurons measure: Concentration of primary olfactory neurons immunohistological signals sex: ALL minimumAge: 7 Weeks maximumAge: 15 Weeks stdAges: CHILD facility: Centre Hospitalier Régional Universitaire - Service ORL city: Nancy country: France name: Roger Jankowski, MD/PhD role: CONTACT email: r.jankowski@chru-nancy.fr lat: 48.68439 lon: 6.18496 hasResults: False
nctId: NCT06260644 id: Repairing defective composite briefTitle: Evaluation of Using Self-adhering Flowable Resin Composite in Repairing Old Defective Resin Composite Restorations Over 18 Months Follow up. (A Randomized Clinical Trial) overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-01 date: 2025-09 date: 2025-10 date: 2024-02-15 date: 2024-02-15 name: Cairo University class: OTHER briefSummary: This research proposal is evaluating the clinical performance of using self-adhering flowable resin composite in repairing old occlusal defective resin composite versus conventional flowable resin composite restoration over 18 months. conditions: Occlusal Caries studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: parallel assignment primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: double ( participants, outcomes assessor) participants and both assessors will be blind to the type of material used whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 34 type: ESTIMATED name: VertiseTM flowable composite (Kerr,USA) measure: Restoration clinical performance using FDI criteria sex: ALL minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: Faculty of Dentistry city: Cairo zip: 113311 country: Egypt lat: 30.06263 lon: 31.24967 hasResults: False