hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06300294 id: AIBU-SBF-AYN-3 briefTitle: Acute Coronary Syndrome and Acupressure overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-04-15 date: 2025-01-31 date: 2024-03-08 date: 2024-03-28 name: Abant Izzet Baysal University class: OTHER briefSummary: This study aims to examine the effect of acupressure on physiological parameters and anxiety levels in individuals diagnosed with Acute Coronary Syndrome (ACS).
H1-6: Acupressure applied to individuals diagnosed with ACS has an effect on cortisol levels. conditions: Acute Coronary Syndrome conditions: Nursing studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: experimental and control primaryPurpose: SUPPORTIVE_CARE masking: TRIPLE maskingDescription: Since block randomization will be used in the study, the research director and the individuals who meet the study inclusion criteria will not know which group they will be in during the preliminary evaluation process of the study. However, the person analyzing the data will not know which group the data belongs to. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 38 type: ESTIMATED name: acupressure measure: means of blood pressure measure: means of hear rate measure: means of respiratory rate measure: means of cortisol. measure: means of subjective anxiety scores. measure: means of subjective pain scores. measure: electrocardiography evaluation sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06300281 id: NEAEGeriatircs briefTitle: Comparison of Neuromuscular and Aquatic Exercise Programs on Fall Risk and Physical Function in Geriatrics acronym: NE-AEinGR overallStatus: NOT_YET_RECRUITING date: 2024-05-04 date: 2024-06-15 date: 2024-10-30 date: 2024-03-08 date: 2024-03-08 name: Alanya Alaaddin Keykubat University class: OTHER name: Pamukkale University briefSummary: Objective: The aim of this study is to compare neuromuscular and aquatic Exercise programs on fall risk and physical function in geriatrics.
Methods: As a result of the power analysis (G-Power), 36 participants are planned to be included in this study Block randomization will be used to divide participants into 2 groups, each with at least 18 participants: Group 1 (NE Group) and Group 2 (AE Group) (Randomizer.org). NE (Neuromuscular Exercise) group will participate in a 12-week exercise program consisting of sensorimotor system training, postural stability and control, global and local joint stabilization, balance training, muscle strength, breathing, and functional movement patterns.AE (Aqıuatic Exercise) Group will participate in an aquatic exercise program, which includes warm-up, mobility and strength, stretching, and cooling exercises in a 140 cm deep pool with a water temperature of 32 °. Data will be collected using the International Physical Activity Survey Short Form (IPAQ-SF), Montreal Cognitive Assessment Scale (MoCA), Geriatric Pain Measure, Optojump-next (Microgate, Bolzano, Italy), 6-minute Walk Test, 30-second-Sit-to-Stand Test, Four Step Square Test, Berg Balance Scale, Fear of Falling Avoidance Behavior Questionnaire.
Practice Implications: This current study will contribute to the understanding of how neuromuscular exercises affect falls and physical function in geriatrics. conditions: Geriatrics conditions: Exercise Therapy conditions: Fall conditions: Physical Functional Performance studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The study will be divided into two parallel groups: The neuromuscular exercise group and the Aquatic exercise group. Both groups will participate in exercise programs for 12 weeks. primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 36 type: ESTIMATED name: Neuromuscular Exercise name: Aquatic Exercise measure: Change in Pain measure: Change in walking and reaction time measure: Change in aerobic capacity measure: Change in muscular fitness measure: Change in s balance measure: Change in dynamic balance measure: Change in fear of falling measure: Physical activity level measure: Level of cognition sex: ALL minimumAge: 65 Years maximumAge: 85 Years stdAges: OLDER_ADULT hasResults: False
nctId: NCT06300268 id: CSPL/PL/2023/004 briefTitle: Advapro Coronary Stent System in Coronary Artery Diseased Patients. acronym: RESTORE overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-06 date: 2026-12 date: 2024-03-08 date: 2024-03-08 name: Advanced MedTech Solutions Pvt. Ltd. class: OTHER briefSummary: A Prospective, Multicentre, Pilot Study to Evaluate the Safety and Performance of the AdvaPro Sirolimus Eluting Coronary Stent System in Coronary Artery Stenosis in Indian and European Population.
Interval(Days) for patients visit at Day 0, Day 30±6, Day 180±8, Day 270±10 and Day 360±14. conditions: Coronary Artery Disease conditions: De Novo Stenosis Lesion conditions: Coronary Stent Implantation studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Pilot Study (Open Label) primaryPurpose: TREATMENT masking: NONE count: 120 type: ESTIMATED name: AdvaPro Sirolimus Eluting Coronary Stent System measure: Composite Endpoint measure: Incidence of DOCE measure: Incidence of POCE measure: Incidence of MACE measure: Target vessel failure (TVF) measure: Non-Target Vessel related Myocardial Infarction measure: Stent thrombosis measure: Device success measure: Procedural Success measure: Acute Device Success measure: For QCA Group measure: For QCA Group measure: For QCA Group sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06300255 id: IRB 00166616 briefTitle: Evaluation of the H.O.O.V.E.S. Healing Intensives Program overallStatus: NOT_YET_RECRUITING date: 2024-04-22 date: 2029-02-01 date: 2029-02-01 date: 2024-03-08 date: 2024-03-08 name: VA Salt Lake City Health Care System class: FED briefSummary: The aim of this study is to measure the impact of these H.O.O.V.E.S. healing intensives on Veteran participants using several psychological instruments. The investigators are planning to administer the demographic questionnaires and psychological instruments to Veteran participants before the healing intensives. Psychological instruments will be administered immediately pre-intervention, pre- and post-session for each session, post-intervention, 90, 120 and 360 days post-intervention. The primary aim is to assess for statistically significant changes pre- to post session and pre- to post-intervention. conditions: Anxiety conditions: PTSD conditions: Depression studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 250 type: ESTIMATED name: H.O.O.V.E.S. Healing Intensives measure: Mean Difference in AAQII pre- to post-session and pre- to post-intervention measure: Mean Difference in PANAS pre- to post-session and pre- to post-intervention measure: Mean Difference in STAI pre- to post-session and pre- to post-intervention measure: Mean Difference in PCL pre- to post-session and pre- to post-intervention measure: Mean Difference in BDI pre- to post-session and pre- to post-intervention measure: Mean Difference in PTGI pre- to post-session and pre- to post-intervention measure: Mean Difference in B-SCS pre- to post-session and pre- to post-intervention measure: Mean Difference in AAQII pre- to post-session measure: Mean Difference in PANAS pre- to post-session measure: Mean Difference in STAI pre- to post-session sex: ALL minimumAge: 18 Years maximumAge: 120 Years stdAges: ADULT stdAges: OLDER_ADULT facility: George E. Wahlen Department of Veterans Affairs Medical Center city: Salt Lake City state: Utah zip: 84148 country: United States lat: 40.76078 lon: -111.89105 hasResults: False
nctId: NCT06300242 id: UP-23-00859 briefTitle: Incentives for Influenza Vaccination overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-17 date: 2024-01-24 date: 2024-02-29 date: 2024-03-08 date: 2024-03-08 name: University of Southern California class: OTHER name: J-PAL North America briefSummary: In this work, we are assessing the impact of messaging with or without a $50 financial incentive on influenza vaccination rates in a county health system. Our main hypothesis is that a message with a $50 financial incentive will increase vaccination rates relative to a control/"treatment as usual" group. We further hypothesize that the financial incentive will increase vaccination rates relative to the message only arm. conditions: Influenza Vaccination studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 66000 type: ESTIMATED name: Reminders name: Financial Incentive name: Placebo measure: Vaccination status at 1 week measure: Vaccination status at 2 weeks measure: Vaccination status at 1 month sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Contra Costa Health Services city: Martinez state: California zip: 94553 country: United States lat: 38.01937 lon: -122.13413 hasResults: False
nctId: NCT06300229 id: 2023-508325-27-00 briefTitle: NAPO - Novel Approach for Oligospermia acronym: NAPO overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-12 date: 2025-12 date: 2024-03-08 date: 2024-03-13 name: Martin Blomberg Jensen class: OTHER briefSummary: This randomized controlled trial aims to assess whether treatment with denosumab can improve semen quality in infertile men selected by serum anti-mullerian hormone (AMH) as a positive predictive biomarker, and with severely impaired semen quality (concentrations between 0.01 million/mL to 2 million/mL). conditions: Infertility, Male studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 42 type: ESTIMATED name: Denosumab name: sodium chloride measure: The difference in sperm concentration (million pr. mL) on day 80 measure: The difference in semen quality (total sperm count, motile sperm, progressive motile sperm and morphologically normal sperm) between baseline and two semen samples delivered at day 80 and day 83 after inclusion measure: The change/differences in number of pregnancies achieved before day 180 measure: The difference in the number of miscarriages throughout the trial before day 180 measure: The change/difference in serum levels of follicle stimulating hormone (FSH) on day 80 measure: The change/difference in serum levels of reproductive hormone luteinizing hormone (LH) on day 80 measure: The change/difference in serum levels of reproductive hormone AMH on day 80 measure: The change/difference in serum levels of reproductive hormone Inhibin B on day 80 measure: The change/difference in CatSper expression on day 80 measure: The change/difference in RANKL expression on day 80 sex: MALE minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Division of Translational Endocrinology, Department of Endocrinology and Internal Medicine city: Copenhagen country: Denmark name: Sam Kafai Yahyavi, MD role: CONTACT phone: +45 35456360 email: sam.kafai.yahyavi.01@regionh.dk name: Mads Joon Jorsal, MD role: CONTACT phone: +45 38683868 email: mads.joon.jorsal@regionh.dk name: Sam Kafai Yahyavi, MD role: PRINCIPAL_INVESTIGATOR name: Mads Joon Jorsal, MD role: SUB_INVESTIGATOR lat: 55.67594 lon: 12.56553 hasResults: False
nctId: NCT06300216 id: KYLL-202401-034-1 briefTitle: A Real-world Study of Octreotide Microspheres in Chinese Patients With Neuroendocrine Tumors overallStatus: NOT_YET_RECRUITING date: 2024-03-26 date: 2027-11-26 date: 2028-05-26 date: 2024-03-08 date: 2024-03-08 name: Qilu Hospital of Shandong University class: OTHER briefSummary: The aim of this multicenter, open-label, observational study is to evaluate the safety and efficacy of octreotide microspheres in the treatment of advanced neuroendocrine tumors in real clinical practice, especially to evaluate the treatment of octreotide microspheres in various subgroups of neuroendocrine tumor patients. conditions: Neuroendocrine Tumors studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 500 type: ESTIMATED name: Octreotide microspheres measure: Treatment Emergent Adverse Events sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Qilu hospital of Shandong University city: Jinan state: Shandong zip: 250012 country: China name: Jian Wang, Dr. role: CONTACT phone: 8618560088226 email: wang.jian@sdu.edu.cn lat: 36.66833 lon: 116.99722 hasResults: False
nctId: NCT06300203 id: CM310_IIS_SAR07 briefTitle: Study of CM310 in Patients With Uncontrolled Seasonal Allergic Rhinitis acronym: MEGREZ overallStatus: NOT_YET_RECRUITING date: 2024-05-30 date: 2025-05-30 date: 2025-05-30 date: 2024-03-08 date: 2024-03-08 name: Beijing Tongren Hospital class: OTHER briefSummary: Allergic rhinitis (AR) is a non-infectious chronic inflammatory disease of the nasal mucosa mainly mediated by immunoglobulin E after exposure to allergens in atopic individuals. The typical symptoms of AR are paroxysmal sneezing, watery rhinorrhea, itching, and nasal congestion, which may be accompanied by ocular symptoms, including eye itching, tearing, redness, and burning sensation, which are more common in patients with hay fever allergies. Bronchial asthma is associated with bronchial asthma in 40% of patients with AR, suggesting a comorbid feature of allergic disease. conditions: Seasonal Allergic Rhinitis studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 80 type: ESTIMATED name: Interleukin-4 receptor responders name: Placebo measure: Average change from baseline in daily retrospective total nasal symptom score (rTNSS) at week 2. sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Beijing Tongren Hospital, Capital Medical University city: Beijing state: Beijing zip: 100000 country: China lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06300190 id: Treatment SLAP type IV lesion briefTitle: Biceps Tenodesis Alone Versus Biceps Tenodesis and Labrum Repair in Superior Labrum Anteroposterior (SLAP) Lesion Type IV overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-06 date: 2025-07 date: 2024-03-08 date: 2024-03-12 name: Assiut University class: OTHER briefSummary: Aim of this study is comparing results Biceps Tenodesis Alone Versus Biceps Tenodesis and labrum Repair in Superior Labrum Anteroposterior (SLAP) Lesion Type IV conditions: SLAP Lesion studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: 2 parallel groups selected by Randomisation primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Aim of this study is comparing outcome results of Biceps Tenodesis Alone Versus Biceps Tenodesis and labrum Repair in Superior Labrum Anteroposterior (SLAP) Lesion Type IV whoMasked: OUTCOMES_ASSESSOR count: 50 type: ESTIMATED name: Biceps tenodesis alone name: Biceps tenodesis and labrum repair measure: Clinical outcome by American shoulder elbow score sex: ALL minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT hasResults: False
nctId: NCT06300164 id: Unripecarobinceliac briefTitle: The Effect of Unripe Carob Fruit in Celiac Patients overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-05-01 date: 2024-07-01 date: 2024-03-08 date: 2024-03-08 name: Toros University class: OTHER briefSummary: The aim of this study was to investigate the effects of the consumption of cookies produced by adding the unripe part of carob fruit, which has high insoluble fiber, polyphenol and antioxidant content, on the oxidative parameters (TAS and MDA), intestinal permeability (zonulin, GIP) and microbiota of celiac patients and to develop new products containing unripe carob fruit for celiac patients in this direction. conditions: Celiac Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The study will conduct by using a prospective randomized double-blind clinical trial model. primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE maskingDescription: Participants will not know which type of cookies to eat. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 30 type: ESTIMATED name: Unripre Carob measure: Examination of between group differences regarding serum Total Antioxidant Capacity (TAC) measure: Examination of between group differences regarding serum Malondialdehyde (MDA) measure: Examination of between group differences regarding serum zonulin measure: Comparison of between group differences regarding serum Total Antioxidant Capacity (TAC) measure: Comparison of between group differences regarding serum Malondialdehyde (MDA) measure: Comparison of between group differences regarding serum zonulin sex: ALL minimumAge: 19 Years maximumAge: 64 Years stdAges: ADULT hasResults: False
nctId: NCT06300138 id: 2023-631-2 briefTitle: Antifungal Agents and Infrared Thermotherapy Alone or in Combination in the Treatment of Sporotrichosis overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-12 date: 2026-12 date: 2024-03-08 date: 2024-03-08 name: First Hospital of China Medical University class: OTHER briefSummary: Sporotrichosis is a chronic granulomatous mycosis caused by sporothrix complex. The course of sporotrichosis is always prolonged and even life-threatening, the treatment of this disease in an important scientific problem to be solved. The investigators previously found the predominance of subtype M2 macrophage which play an anti-inflammatory role in the lesions of sporotrichosis, the predominance of M2 macrophage may be responsible for the persistence of sporotrichosis; the investigators also found that local hyperthermia is effective in the treatment of sporotrichosis and hyperthermia treatment can activate the CRAC calcium channel in macrophages which triggers pro-inflammatory type M1 polarization and subsequent killing of sporothrix, however, the mechanism still calls for further investigation. The investigators hypothesize that hyperthermia leads to the activation of CRAC channels resulting in profound Ca2+ influx and Ca2+ upregulates NLRP3 inflammasome expression through inducing Nrf2 activation, then NLRP3 overexpression triggers M1 polarization and subsequent killing of sporothrix. Furthermore, the activation of Nrf2 upregulates STIM1 expression which forms a positive feedback for M1 type polarization of macrophages and further subsequent killing of sporothrix. The purpose of this project is to identify the hypothesis that hyperthermia could treat sporotrichosis by promoting pro-inflammatory type M1 polarization in macrophages, the mechanism by which hyperthermia could treat sporotrichosis is local hyperthermia could led to STIM1/CRAC calcium channel activation mediated calcium ions/Nrf2/NLRP3 induced M1 macrophages polarization and subsequent killing of sporothrix. The hypothesis will be identified at the cellular level, at the animal model level and at the clinical specimens level. The investigators believe that the project will guide the application of hyperthermia in the treatment of sporotrichosis and provide a new basis of theory and practice after the investigators achieving these goals. conditions: Sporotrichosis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 150 type: ESTIMATED name: Itraconazole name: Infrared thermotherapy apparatus name: Itraconazole and Infrared thermotherapy apparatus measure: the overall clinical clearance rate of skin lesions measure: Overall clinical clearance rate and recurrence rate measure: adverse reactions and incidence measure: the clearance rate of target skin lesions measure: overall lesion clearance rate sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06300125 id: R1881/23 - L2-015 briefTitle: Percutaneous Cryoablation of Low-risk Early Breast Cancer acronym: PRECICE overallStatus: RECRUITING date: 2024-04-15 date: 2026-12-31 date: 2031-03-01 date: 2024-03-08 date: 2024-04-03 name: European Institute of Oncology class: OTHER name: Fondazione Umberto Veronesi name: IceCure Medical Ltd. briefSummary: Expand the current evidence base regarding percutaneous cryoablation of early-stage, low-risk breast tumors, integrated into the standard therapeutic pathway with well-defined follow-up data, as well as data on quality of life. Demonstrate, therefore, that the use of percutaneous cryoablation in the treatment of low-risk breast carcinoma is not inferior to surgery when combined with adjuvant radiotherapy and chemotherapy (when necessary). The hypothesis is that cryoablation, being simple and oncologically effective, ensures a better quality of life for the patient (reduced morbidity, no need for general anesthesia, improved cosmetic outcomes) and consequently has a lesser psychological impact, as well as a better cost-benefit ratio compared to the standard surgical approach. conditions: Breast Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 234 type: ESTIMATED name: Cryoablation measure: Procedure failure rate measure: Assessment of subject's quality of life in terms of evaluation of sources of distress measure: Assessment of subject's satisfaction measure: Cost-analysis - evaluation of cost of intervention, hospitalization and re-intervention (if applicable) measure: Ipsilateral breast tumor recurrence measure: Distant metastasis sex: ALL minimumAge: 50 Years stdAges: ADULT stdAges: OLDER_ADULT facility: European Institute of Oncology status: RECRUITING city: Milan country: Italy name: Franco Orsi role: CONTACT lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06300112 id: Amasya Univ_emine.akca briefTitle: Prenatal Yoga on Stress, Quality of Sexual Life and Sleep Level overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2024-05-31 date: 2024-06-30 date: 2024-03-08 date: 2024-03-12 name: Amasya University class: OTHER briefSummary: The study will investigate the effects of pregnancy yoga on perceived stress, quality of sexual life and sleep level. A total of 100 pregnant women are planned to be included in the study. Data will be collected with the "Personal Information Form", "Perceived Stress Scale" and "Sexual Quality of Life Questionnaire-Female". Yoga will be applied to the experimental group for a total of 12 sessions, two sessions per week (90 minutes) for six weeks. The research predicts that yoga will reduce the stress perceived by pregnant women, increase the quality of sexual life and positively affect sleep patterns. conditions: Stress conditions: Sexuality conditions: Sleep studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A randomized-controlled trial with pretest-posttest control group primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 100 type: ESTIMATED name: YOGA measure: Perceived stress level measure: Sexual Quality of Life measure: Sleep patterns sex: FEMALE minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: Amasya University city: Amasya zip: 05100 country: Turkey name: Emine İbici Akça, Ph.D role: CONTACT phone: 03582115005-4723 email: emine.akca@amasya.edu.tr lat: 40.65333 lon: 35.83306 hasResults: False