hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06317168 id: SIMPLE-AOBP briefTitle: SIMPLifying Elements of Standardized Automated Office Blood Pressure Measurements (Pilot Study) acronym: SIMPLE-AOBP overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-08-31 date: 2024-08-31 date: 2024-03-19 date: 2024-03-19 name: Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal class: OTHER briefSummary: This study aims to assess whether removing single elements of the standardized office BP measurement procedure will affect the accuracy towards the mean awake ambulatory BP. Four arms are planned in a randomized order: 1) full standardized procedure, 2) standardized procedure but with cuff placed on a sleeve, 3) standardized procedure but arm resting vertically, 4) standardized procedure but with non-validated device.
This is a pilot study to inform on the sample size required to perform adequately powered large scale studies. conditions: Blood Pressure studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: DIAGNOSTIC masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 30 type: ESTIMATED name: Mean awake ambulatory BP measurements measure: Difference with mean awake ambulatory systolic BP measure: Difference with mean awake ambulatory diastolic BP sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06317155 id: BournemouthU-AS briefTitle: Occupational Therapy for Children and Young People Who Self-harm: A Qualitative Study overallStatus: NOT_YET_RECRUITING date: 2024-12 date: 2025-09 date: 2025-12 date: 2024-03-19 date: 2024-03-19 name: Bournemouth University class: OTHER name: Dorset HealthCare University NHS Foundation Trust briefSummary: The goal of this qualitative observational study is to explore the experiences of children and their carers, receiving occupational therapy for self-harm and the experiences of health professionals delivering these interventions. The child cohort within the study will have a history of self-harm and have been under the care of Children and Adolescent Mental Health Services.
Participants will be asked to complete a questionnaire and take part in a single semi-structured interview. 25% of participants may be asked to take part in a further in depth semi-structured interview. conditions: Self Harm studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 30 type: ESTIMATED name: Occupational therapy measure: What was the participants experience of receiving or delivering an occupational therapy informed intervention? measure: What was the participants experience of receiving or delivering an occupational therapy informed intervention? measure: Did the participants feel the occupational therapy informed interventions were effective in supporting young people who self-harm or effective in reducing self-harm? measure: Did the participants feel the occupational therapy informed interventions were effective in supporting young people who self-harm or effective in reducing self-harm? sex: ALL minimumAge: 13 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06317142 id: NL84574.068.23 briefTitle: Glucose and Glycogen Dynamics in Prediabetes acronym: GGD overallStatus: RECRUITING date: 2024-02-20 date: 2025-07 date: 2025-07 date: 2024-03-19 date: 2024-04-09 name: Maastricht University Medical Center class: OTHER briefSummary: The goal of this observational study is to investigate changes in nocturnal and postprandial glucose and glycogen metabolism in individuals with impaired fasting glucose and impaired glucose tolerance compared to healthy, non-diabetic, overweight participants (15 per group). In addition, it will be investigated if reducing gluconeogenesis, by using the challenge agent Acipimox, in people with prediabetes can increase glucose tolerance and fat oxidation by increased reliance on hepatic glycogen. The main questions this project aims to answer are:
Participants will visit the university for a screening visit and a visit with overnight stay for measurements of gluconeogenesis, glycogen, and substrate oxidation. A subgroup will receive \[18F\]-FDG to assess tissue-specific postprandial glucose uptake. Thereafter, 20 prediabetic individuals will follow a 4-day treatment with acipimox to decrease gluconeogenesis, followed by a second overnight visit with similar measurements as mentioned for the first visit. conditions: Pre Diabetes studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: CROSS_SECTIONAL count: 45 type: ESTIMATED name: Acipimox 250 mg Oral Capsule measure: Hepatic and muscle glycogen measured by 13Carbon-Magnetic resonance spectroscopy (13C-MRS) measure: Whole body gluconeogenesis determined by deuterated water measure: Postprandial hepatic and muscle glucose uptake determined by Fluorodeoxyglucose-Positron emission tomography ([18F]-FDG-PET) combined with oral glucose tolerance test (OGTT) measure: Oral glucose tolerance after acipimox treatment measured by OGTT measure: Hepatic glycogen after acipimox treatment measured by 13C-MRS measure: Whole body gluconeogenesis after acipimox treatment determined by deuterated water measure: Hepatic acetylcarnitine as a measure for hepatic gluconeogenesis determined by H-MRS measure: Substrate oxidation (fat and carbohydrate oxidation) determined by indirect calorimetry measure: Dynamic water relaxation measurements with 1H-MRS (surrogate glycogen) measure: Anthropometric measurements measure: Body composition determined by Bodpod sex: ALL minimumAge: 45 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Maastricht University status: RECRUITING city: Maastricht state: Limburg zip: 6229ER country: Netherlands name: Kay Roumans, PhD role: CONTACT phone: 433882124 phoneExt: 31 email: k.roumans@maastrichtuniversity.nl lat: 50.84833 lon: 5.68889 hasResults: False
nctId: NCT06317129 id: CP000005 briefTitle: Clinical Feasibility Study of the BariTon™ System in Obese Patients overallStatus: RECRUITING date: 2024-01-18 date: 2024-10-31 date: 2026-01-31 date: 2024-03-19 date: 2024-03-19 name: BariaTek Medical class: INDUSTRY briefSummary: Safety evaluation of BariaTek Medical gastric restriction and biliodigestive diversion device. conditions: Obesity studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 10 type: ESTIMATED name: Endoscopic gastric restriction and biliodigestive diversion measure: Safety of the BariTon™ measure: Safety of the BariTon™ measure: Safety of the BariTon™ measure: Safety of the BariTon™ measure: Efficacy of the BariTon™ measure: Efficacy of the BariTon™ measure: Efficacy of the BariTon™ measure: Efficacy of the BariTon™ measure: Efficacy of the BariTon™ measure: Efficacy of the BariTon™ sex: ALL minimumAge: 25 Years maximumAge: 60 Years stdAges: ADULT facility: Republican Specialized Scientific and Practical Medical Center of Surgery named after V. Vakhidov status: RECRUITING city: Tashkent country: Uzbekistan name: Abdurashid Abdukarimov, Dr role: CONTACT lat: 41.26465 lon: 69.21627 hasResults: False
nctId: NCT06317116 id: 2023/09-14 briefTitle: Examining the Relationship Between Core Muscles and Bladder Issues in Children overallStatus: ENROLLING_BY_INVITATION date: 2023-09-29 date: 2024-09-29 date: 2025-03-01 date: 2024-03-19 date: 2024-03-19 name: Izmir Bakircay University class: OTHER name: Dokuz Eylul University name: Ege University Medical School name: The Scientific and Technological Research Council of Turkey briefSummary: The goal of this observational study is to learn about functional bladder problems in children. The main questions it aims to answer are:
* How do core muscles change based on an increase or decrease in these symptoms? conditions: Lower Urinary Tract Symptoms conditions: Skeletal Muscle studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 60 type: ESTIMATED measure: Dysfunctional Voiding and Incontinence Scoring System (DVAISS) measure: Bladder and Bowel Dysfunction Questionnaire (BBDQ) measure: Childhood Bladder and Bowel Dysfunction Questionnaire (CBBDQ) measure: Bladder Diary measure: Bowel Diary measure: Superficial Electromyography (EMG) measure: Ultrasonography (USG) sex: ALL minimumAge: 6 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Ege University Hospital Pediatric Urology Outpatient Clinic city: İzmir country: Turkey lat: 38.41273 lon: 27.13838 hasResults: False
nctId: NCT06317103 id: WAY-CTP-WME01-MSM briefTitle: A Clinical Trial to Evaluate the Sensitivity and Specificity of "WAYMED Endo" Compared to the Endoscopists in Classifying Early Gastric Cancer (EGC) Based on the Depth of Invasion in Endoscopic Images overallStatus: COMPLETED date: 2023-08-22 date: 2023-08-22 date: 2023-08-22 date: 2024-03-19 date: 2024-03-19 name: WAYCEN Inc class: INDUSTRY briefSummary: The purpose of this clinical trial is to prove that the prediction capability of 'WAYMED endo' is superior to that of the endoscopists in classifying EGC based on the depth of invasion categories in gastro-endoscopic images.
The computer-aided detection·diagnosis software is an Artificial Intelligence (AI) software used to assist medical specialists in diagnostic decisions by automatically classifying EGC based on the depth of invasion categories in gastro-endoscopic images and displaying the results and possibilities on the User Interface (UI). conditions: Early Gastric Cancer studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: RETROSPECTIVE count: 653 type: ACTUAL name: WADYMED endo name: Control group (the endoscopists) measure: Clinical Sensitivity in classifying early gastric cancer (EGC) based on the depth of invasion (%) measure: Clinical Specificity in classifying early gastric cancer (EGC) based on the depth of invasion (%) measure: Accuracy in classifying the depth of invasion categories ("Mucosa" or "Submucosa") for early gastric cancer (%) sex: ALL minimumAge: 19 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Yonsei University Gangnam Severance Hospital city: Seoul country: Korea, Republic of lat: 37.566 lon: 126.9784 hasResults: False
nctId: NCT06317090 id: S59813-2 briefTitle: Vertical GBR LPRF Block vs. Autogenous Bone With DBBM overallStatus: COMPLETED date: 2018-07-02 date: 2023-03-01 date: 2023-03-01 date: 2024-03-19 date: 2024-03-19 name: Universitaire Ziekenhuizen KU Leuven class: OTHER briefSummary: split-mouth RCT, 25 months follow up. GBR protocol with LPRF as grafting material in the test group and autogenous bone with DBBM as grafting material in the control group. conditions: Alveolar Bone Resorption studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: split-mouth 2 arm RCT primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: neither the patient, nor the outcome assessor was aware at which side which grafting material was used whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 6 type: ACTUAL name: guided bone regeneration measure: bone volume as measured on CBCT scans measure: Buccal bone thickness around the implants measure: Buccal bone thickness around the implants measure: Cumulative survival rate of the implants measure: rates and types of complications sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: UZ Leuven city: Leuven state: Vlaams-Brabant zip: 3000 country: Belgium lat: 50.87959 lon: 4.70093 hasResults: False
nctId: NCT06317077 id: I5-R1-C-FA briefTitle: Investigation of the Accordance Between Event Detection of prismaLINE Devices and Polysomnography Using Full Face Masks acronym: EventLAB FF overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2025-05-15 date: 2025-05-15 date: 2024-03-19 date: 2024-03-19 name: Löwenstein Medical Technology GmbH & Co. KG class: INDUSTRY briefSummary: Sleep-related breathing disorders are highly prevalent and are usually treated with positive airway pressure (PAP) therapy. To determine the quality of therapy, PAP therapy devices measure the frequency of residual breathing events. For this purpose, breathing events of different classes are detected, counted and identified.
The most relevant inclusion criteria are diagnosis of a sleep-related breathing disorder and indication for therapy with continuous positive airway pressure (CPAP). Treatment takes place with prismaLINE PAP therapy devices in combination with LM full face masks. conditions: Sleep Apnea Syndromes studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 48 type: ESTIMATED name: PAP therapy setting name: exclusive use of Löwenstein Medical full face masks measure: Delta AHI [n/h]= Difference of device AHI (prismaLINE devices of the type WM100TD) and the manual scored AHI of polysomnographic data identified in the Matlab-based SOMNOmat tool measure: N_AE device [n]= number and severity of occurred (predictable) adverse events and (predictable) adverse device effects, counted during study duration measure: Mask fit score= Leakage, pressure points, stable pressure level, comfort determined via questionnaire measure: N_AE mask [n]= number and severity of occurred (predictable) adverse events and (predictable) adverse device effects, counted during study duration measure: Delta AI [n/h]= difference of apnea-indices (obstructive/central/mixed) between the therapy device and the manually evaluated PSG data identified in the Matlab-based tool SOMNOmat measure: Delta HI [n/h]= difference of hypopnea-indices (obstructive/central) between the therapy device and the manually evaluated PSG data identified in the Matlab-based tool SOMNOmat measure: Delta Event_individual [n]= difference of the number (with time, duration, type) of residual breathing events (apneas/hypopneas) device vs. PSG identified in the Matlab-based tool SOMNOmat measure: N_influenced phases [n]= number (with time, duration, type) of phases with significant deviations between the synchronized device and PSG files identified in the Matlab-based tool SOMNOmat measure: Delta AHI_1A [n/h]= difference between apnea indices using scoring rule 1A from AASM manual version 3.0 measure: Delta AHI_1B [n/h]= difference between apnea indices using scoring rule 1B from AASM manual version 3.0 measure: Delta AHI_mean [n/h]= difference between apnea indices using mean of scoring rule 1A and 1B from AASM manual version 3.0 (AHI_1A + AHI_1B)/2 measure: Delta AHI_Routine [n/h]= difference between unmachined apnea indices of device and PSG measure: N_impact factors [n]= number and type of factors that can increase the risk for sleep related breathing disorders like comorbidities and smoking measure: corr_flow-sleep= correlation between flow signal and sleep state measure: corr_marker= correlation between diagnostic sleep apnea syndrom markers with medical history data, biomarkers of the diagnostic night, therapy pressure and sleep stage sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Krankenhaus Bethanien city: Solingen state: NRW zip: 42699 country: Germany name: Marc Treml, Dr. role: CONTACT lat: 51.17343 lon: 7.0845 hasResults: False
nctId: NCT06317064 id: LMRC-Aprepitant-Pain-01 briefTitle: Diagnostic and Therapeutic Potential of Substance P/ NK1R Receptor in Primary Dysmenorrhea overallStatus: COMPLETED date: 2023-01-15 date: 2023-10-31 date: 2024-01-31 date: 2024-03-19 date: 2024-03-19 name: Lahore Medical Research Center, LLP class: INDUSTRY briefSummary: Dysmenorrhea is characterized as excruciating menstrual cramps of uterine origin and is one of the most prevalent gynecological illnesses. Substance P (SP) and NK1R mediate the symptoms of various pain disorders with chronic and/or neuropathic pain. Objective: To evaluate diagnostic and therapeutic potential of Substance P/ NK1R receptor in primary dysmenorrhea. Study Design: This was a randomized controlled trial which took place at Lahore Medical Research Center from April 2023 to August 2023. Non-probability convenient sampling techniques was used for sampling. A total of 40 female participants was included in the study who met specific criteria for inclusion. The study comprised of three phases, Phase 1 (Before medication), Phase 2 (NSAIDs) and Phase 3(Dexamethasone + Aprepitant). 10 females with no dysmenorrhea participated as controls. The study duration spanned three menstrual cycles. 20 dysmenhorric and 6 controls were analyzed for NK1R levels. Several assessment tools were also used in the study, conditions: Primary Dysmenorrhea studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: Group 1: Controls 10 females with no dysmenorrhea participated as controls. Group 2: NSAIDS All 30 participants in this group used NSAIDs (Non-steroidal Anti-Inflammatory Drugs), during their dysmenorrhea period. Same patients from phase 2 (n=30) in next cycle received NK1R antagonist "Dexamethasone (6mg) + Aprepitant (80mg)" for 2 days. primaryPurpose: TREATMENT masking: NONE count: 40 type: ACTUAL name: Ibuprofen and Aprepitant measure: Visual Analogue Scale Score (Pain scale) measure: Mini Nutritional Assessment (MNA) Score measure: DASS-21 (Depression Anxiety Stress Scale) measure: Pictorial Blood Loss Assessment Chart (PBAC) sex: FEMALE minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Prof. Dr. Riffat Mehboob city: Lahore state: Punjab zip: 54000 country: Pakistan lat: 31.558 lon: 74.35071 hasResults: False
nctId: NCT06317038 id: 89814415 briefTitle: To Evaluate the Performance of Total 30 (Lehifilcon A) Contact Lenses in Patients Using Digital Devices for Greater Than 8 Hours Per Day 5 Days Per Week Based on Subjective Reported Data. overallStatus: NOT_YET_RECRUITING date: 2024-03-31 date: 2024-11 date: 2025-01 date: 2024-03-19 date: 2024-03-27 name: Tauber Eye Center class: OTHER name: Alcon Research briefSummary: To evaluate the performance of Total 30® (lehfilcon A) contact lenses in patients using digital devices for greater than 8 hours per day 5 days per week based on subjective reported data. conditions: Eye Strain studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Open label Observation primaryPurpose: OTHER masking: NONE count: 40 type: ESTIMATED name: Total 30 Contact Lens measure: Likert question about comfort satisfaction while wearing Total 30 contact lenses on a typical day (> 13 hours of daily wear) after 1 month of wear and heavy digital device usage (>8 hours daily wear). measure: Likert responses to insertion comfort and overall vision, and heavy digital device use on a typical day after 1 month of wear. measure: Results of subjective ratings of patients using Total 30 lenses and heavy digital device usage with VAS diary questionnaire. measure: Report on total daily wear time and digital device usage. sex: ALL minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT hasResults: False
nctId: NCT06317025 id: SHOUFA2022-2Z-2039 briefTitle: Design and Development of Multi-modal Intelligent Anesthesia Monitoring System overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-12 date: 2025-12 date: 2024-03-19 date: 2024-03-19 name: Beijing Chao Yang Hospital class: OTHER briefSummary: This project integrates the characteristics of electroencephalo-graph（EEG）, cerebral oxygen, blood pressure, heart rate, etc., based on nonlinear theory and neural oscillation, large sample data and machine learning theory, to develop a multi-modal monitoring system suitable for domestic patients, taking into account changes in sedation, analgesia, cerebral hemodynamics and other factors, regardless of patient age and type of general anesthesia drugs. conditions: Anesthesia studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 330 type: ESTIMATED name: Multi-modal Intelligent Anesthesia Monitoring System measure: the depth of anesthesia (too deep or too shallow) measure: EEG characteristics of loss of consciousness induced by different general anesthesia drugs measure: Characteristics of perioperative neurovascular coupling sex: ALL maximumAge: 85 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06317012 id: 0407-03/2022 briefTitle: Computer-Aided Design/Manufacturing for Le Fort I Osteotomy and 3D-customized Titanium Plate in Orthognathic Surgery overallStatus: COMPLETED date: 2022-05-01 date: 2023-05-30 date: 2023-06-30 date: 2024-03-19 date: 2024-03-19 name: Hams Hamed Abdelrahman class: OTHER briefSummary: Background: In orthognathic surgery, virtual planning is gradually taking over in clinical practice. To start with, virtual surgery planning (VSP) is believed to be less time-consuming and less expensive than conventional surgery planning (CSP). Moreover, the improved visualization of craniofacial deformities, such as occlusal canting and asymmetries, is a further advantage. Aim: To assess the result of Le Fort I osteotomy using CAD/CAM and 3Dcustomized titanium plate with virtual planning in orthognathic surgery. Materials and Methods: 8 patients with vertical maxillary excess will be included in the study. Le Fort I osteotomy using CAD CAM surgical guide and 3Dcustomized plate will be done for the study group. All patients will be followed clinically and radiographically for one month. conditions: Le Fort; I studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 8 type: ACTUAL name: Le Fort I osteotomy using CAD CAM surgical guide and 3Dcustomized plate measure: Change in pain measure: change in edema measure: Change in post operative osteotomy position sex: ALL minimumAge: 20 Years maximumAge: 40 Years stdAges: ADULT facility: Alexandria Faculty of Dentistry city: Alexandria country: Egypt lat: 31.21564 lon: 29.95527 hasResults: False
nctId: NCT06316999 id: 23-012169 briefTitle: Intestinal Ultrasound for the Evaluation of Pouchitis and Other Outcomes After Ileal Pouch-Anal Anastomosis overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2025-06 date: 2025-06 date: 2024-03-19 date: 2024-03-19 name: Mayo Clinic class: OTHER briefSummary: Intestinal ultrasound (IUS) has been studied in the evaluation of inflammatory bowel disease (IBD) and is increasingly used as a non-invasive, easy to use, cost-effective tool for point-of-care to assess disease activity and more recently to predict response to treatment. However, there is a paucity of data on the use of IUS specifically for ulcerative colitis (UC) patients with an ileal pouch-anal anastomosis (IPAA). conditions: Ulcerative Colitis conditions: Pouchitis studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 50 type: ESTIMATED name: Intestinal Ultrasound measure: Diagnostic accuracy of intestinal ultrasound (IUS) for pouchitis sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mayo Clinic city: Rochester state: Minnesota zip: 55905 country: United States name: Darrell Pardi, MD, MS role: CONTACT phone: 507-284-2511 email: pardi.darrell@mayo.edu lat: 44.02163 lon: -92.4699 hasResults: False
nctId: NCT06316986 id: 2023-A02294-41 briefTitle: Performance of the NGPOD® Device in Verifying the Correct Position in the Stomach of the Naso- or Oro- Gastric Tube in Intensive Care. acronym: NGPOD overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-04-01 date: 2025-04-01 date: 2024-03-19 date: 2024-03-19 name: Fondation Hôpital Saint-Joseph class: OTHER briefSummary: In the ICU, scientific societies recommend starting enteral nutrition within 48 hours of admission, if oral nutrition is not available, in order to limit undernutrition. In patients who are sedated, have swallowing problems or cannot ensure adequate caloric intake, it is essential to insert a feeding tube, usually a nasogastric or orogastric tube for the first few weeks.