hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06275906 id: NAFLD-POS5 briefTitle: Influence of a Mediterranean Diet Combined With a Physical Activity Intervention, on NAFLD and Inflammation Parameters. acronym: NAFLD-POS5 overallStatus: NOT_YET_RECRUITING date: 2024-04-08 date: 2025-04-08 date: 2026-04-08 date: 2024-02-23 date: 2024-02-23 name: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis class: OTHER name: Russo Francesco name: Cozzolongo Raffaele name: Shahini Endrit name: Zappimbulso Marianna name: Giannuzzi Vito name: De Nucci Sara name: Rinaldi Roberta name: Sila Annamaria name: Tatoli Rossella name: Cerabino Nicole name: Donghia Rossella name: Franco Isabella name: Bianco Antonella name: Curci Ritanna name: Bagnato Claudia Beatrice name: Sciarra Sabrina name: Prospero Laura name: Serino Grazia name: Scalavino Viviana name: Piccinno Emanuele name: Pesole Pasqua Letizia name: Coletta Sergio name: Stabile Dolores name: Riezzo Giuseppe name: Ancona Anna name: D'Attoma Benedetta name: Ignazzi Antonia briefSummary: The study in question is an interventional study with nutritional intervention.
The Mediterranean Diet is associated with a program of moderate intensity aerobic physical exercise (walking) carried out 3 times a week for 3 months. primaryPurpose: TREATMENT masking: NONE count: 60 type: ESTIMATED name: Mediterranean diet and moderate intensity physical exercise (outdoor walking). measure: The effect of intervention on CAP value measure: The effect of intervention on FLI value measure: The effect of intervention on routine blood chemistry parameters, relating to NAFLD and fibrosis, nutritional status, inflammatory status and metabolic and cardiovascular risk measure: The effect of the intervention on the integrity of the intestinal barrier measure: The effect of the intervention on the Gastrointestinal Symptoms measure: The effect of the intervention on the Body Composition sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Irccs Saverio de Bellis city: Castellana Grotte state: Bari zip: 70013 country: Italy lat: 40.88643 lon: 17.16549 hasResults: False
nctId: NCT06275893 id: ACM01 briefTitle: IC14 (Atibuclimab) in Arrhythmogenic Cardiomyopathy overallStatus: RECRUITING date: 2024-03-29 date: 2025-02-01 date: 2025-08-01 date: 2024-02-23 date: 2024-04-02 name: Implicit Bioscience class: INDUSTRY briefSummary: The goal of this clinical trial is to test IC14 (atibuclimab) in patients with arrhythmogenic cardiomyopathy (ACM) and who have an implantable cardoverter/defibrillator in place. ACM is also called arrhythmogenic right ventricular dysplasia (ARV) or arrhythmogenic right ventricular cardiomyopathy (ARVC). The main questions the study aims to answer are the effect of treatment on blood markers of inflammation, safety, and pharmacokinetics. There will also be measurements of myocardial imaging of C-C chemokine receptor type 2 (CCR2+) immune cells (optional), monitoring of cardiac arrhythmias using the patient's pre-existing intracardiac cardioverter/defibrillator (ICD) and a Holter monitor, electrocardiogram (ECG), echocardiogram (ECHO), and blood tests. Results will be compared to baseline; there is no inactive placebo treatment group.
Participants will be asked to undergo screening and baseline testing, then receive 4 intravenous infusions with blood measurements before and after the infusion (including 24, 48, and 72 hours and 7, 14, and 28 days). Participants will be offered specialized scanning of the heart muscle, and will be asked to provide recordings from their ICD, undergo Holter monitoring twice, and have electrocardiograms (ECG), echocardiograms (ECHO) and blood tests. conditions: Arrhythmogenic Right Ventricular Dysplasia conditions: Arrhythmogenic Left Ventricular Cardiomyopathy conditions: Arrhythmogenic Right Ventricular Cardiomyopathy 1 conditions: Arrhythmogenic Cardiomyopathy studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Open-label treatment with IC14. Participant outcomes will be compared to baseline. Pharmacokinetics will be measured. primaryPurpose: TREATMENT masking: NONE count: 5 type: ESTIMATED name: IC14 measure: Safety: Treatment-emergent adverse events and serious adverse events measure: Safety: Incidence of anti-drug antibodies measure: Inflammatory biomarker C-reactive protein measure: CCR2+ Myocardial Imaging (optional) measure: Ventricular tachycardia measure: Ventricular premature contractions measure: Sustained and non-sustained ventricular tachycardia measure: Treated ventricular tachycardia measure: Atrial premature contractions measure: New York Heart Association (NYHA) Functional Class measure: Implantable cardioverter/defibrillator (ICD) discharges measure: Quality-of-Life Score determined by the Kansas City Cardiomyopathy Questionnaire measure: Disease biomarker Troponin I measure: Disease biomarker N-terminal B-type natriuretic peptide (NT-pro-BNP) measure: Inflammatory biomarker interleukin (IL)1-beta measure: Pharmacokinetics: Serum IC14 concentration versus time curve measure: Pharmacokinetics: Peak serum IC14 concentration measure: Pharmacokinetics: Half life measure: Pharmacodynamics: Receptor Occupancy measure: Pharmacodynamics: Effective Concentration 95% sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Washington University School of Medicine status: RECRUITING city: Saint Louis state: Missouri zip: 63110 country: United States name: Philip S. Cuculich, MD role: PRINCIPAL_INVESTIGATOR lat: 38.62727 lon: -90.19789 hasResults: False
nctId: NCT06275880 id: F-2023-3201-066 briefTitle: Intraarticular Collagen in Patients With Gonarthrosis overallStatus: COMPLETED date: 2023-04-01 date: 2023-07-30 date: 2024-01-10 date: 2024-02-23 date: 2024-02-23 name: Instituto Mexicano del Seguro Social class: OTHER_GOV briefSummary: The objective of this clinical trial is to verify the effectiveness of polyvinyl pyrrolidone collagen in all patients with symptomatic gonarthrosis grades II-IV in patients over 40 years of age. The main objectives that this study aims to answer are the following:
Patients diagnosed with symptomatic gonarthrosis Grade II-IV, referred to the Physical Medicine and Rehabilitation service within 3 months, will be selected. Two study groups will be assigned: GROUP those who received intra-articular infiltration of PVP Collagen, GROUP B: patients who received conservative treatment. Through rehabilitation with a home program for one month, in both cases, ENA and the WOMAC scale will be evaluated at the beginning of the study and after 4 weeks. conditions: Gonarthrosis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: NONE count: 130 type: ACTUAL name: Intra-articular infiltration of PVP Collagen name: Rehabilitation measure: Western Ontario and McMaster Universities Osteoarthritis Index - Pain measure: Western Ontario and McMaster Universities Osteoarthritis Index - stiffness measure: Western Ontario and McMaster Universities Osteoarthritis Index - functionality measure: Number Analog Scale for pain sex: ALL minimumAge: 40 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hospital General Regional No. 1 Lic. Ignacio García Téllez city: Mérida state: Yucatán zip: 97155 country: Mexico lat: 20.97537 lon: -89.61696 hasResults: False
nctId: NCT06275867 id: SOPRIMA//T023635 briefTitle: Improved Access to Quality Care and Healthcare Use overallStatus: RECRUITING date: 2024-01-20 date: 2024-06-10 date: 2024-08-30 date: 2024-02-23 date: 2024-02-23 name: London School of Economics and Political Science class: OTHER name: University of Witwatersrand, South Africa briefSummary: This study is an individual-level randomised controlled trial which looks at the effect of providing free access to higher quality providers in urban South Africa. The study will recruit about 1,500 individuals with a child aged 5 or under. They will be randomly allocate to a control group (CONTROL) with the default free access to government facilities or one of the two treatment groups where they will have free access to private providers located either relatively close (CONVENIENT) by or relatively far (INCONVENIENT). The primary outcomes be overuse and underuse of healthcare services for children under 5 conditions: Health Care Utilization conditions: Health Knowledge, Attitudes, Practice conditions: Health, Subjective studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: SINGLE whoMasked: CARE_PROVIDER count: 1500 type: ESTIMATED name: Free high-quality care name: Close distance name: Far distance measure: Underuse measure: Overuse measure: Illness duration measure: Out-of-pocket expenditures measure: Health knowledge sex: ALL minimumAge: 2 Months maximumAge: 6 Years stdAges: CHILD facility: HDSS Soweto clusters status: RECRUITING city: Soweto state: Gauteng country: South Africa name: Nomalanga Boyce role: CONTACT email: nomalanga.boyce@wits-vida.org lat: -26.26781 lon: 27.85849 hasResults: False
nctId: NCT06275854 id: 22265 briefTitle: YASU Research Registry: For Young Adults With Cancer overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2030-05-01 date: 2030-05-01 date: 2024-02-23 date: 2024-02-23 name: Young Adult Survivors United class: OTHER name: Staunton Farm Foundation name: Elsie H. Hillman Foundation briefSummary: The goal of this observational research registry is to learn about health, wellbeing, and needs of survivors of young adult cancer (diagnosed between the ages of 18 and 39). The main question\[s\] it aims to understand are:
Participants will be asked to complete electronic surveys every 6 to 12 months during participation in the registry. conditions: Cancer conditions: Leukemia conditions: Sarcoma conditions: Germ Cell Cancer conditions: Lymphoma conditions: Colorectal Cancer conditions: Melanoma conditions: Breast Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 5000 type: ESTIMATED measure: Anxiety measure: Depressive symptoms measure: Social Support measure: Financial Toxicity measure: Needs Assessment measure: Name, address, email, phone number sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06275841 id: C4891035 briefTitle: A Study to Learn If the Study Medicine Esomeprazole Changes How the Body Processes the Other Study Medicine Vepdegestrant overallStatus: RECRUITING date: 2024-02-23 date: 2024-05-03 date: 2024-05-24 date: 2024-02-23 date: 2024-03-22 name: Pfizer class: INDUSTRY name: Arvinas Estrogen Receptor, Inc. briefSummary: The purpose of the study is to investigate the effect of multiple doses of a proton-pump inhibitor (PPI) esomeprazole on the PK of vepdegestrant under fed conditions in healthy adult participants.
All participants in this study will receive one dose of vepdegestrant alone by mouth in Period 1. In Period 2, everyone will receive esomeprazole by mouth once a day for multiple days. Participants will also receive one dose of vepdegestrant by mouth. The levels of vepdegestrant in Period 1 will be compared to the levels of vepdegestrant in Period 2 to determine if the PPI affects how vepdegestrant is processed differently in healthy adults. conditions: Healthy studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: CROSSOVER primaryPurpose: OTHER masking: NONE count: 12 type: ESTIMATED name: vepdegestrant name: esomeprazole measure: Maximum observed plasma concentration (Cmax) of vepdegestrant when vepdegestrant is administered alone measure: Maxium observed plasma concentration of vepdegestrant when vepdegestrant is administered with esomeprazole measure: Area under the curve from time zero to extrapolated infinite time (AUCinf) when vepdegestrant is administered alone measure: Area under the curve from time zero to extrapolated infinite time (AUCinf) when vepdegestrant is administered with esomeprazole measure: number of participants with treatment-emergent adverse events (AEs) and serious adverse events (SAEs) measure: Number of participants with clinical laboratory abnormalities measure: Number of participants with electrocardiogram (ECG) abnormalities measure: Number of participans with clinically significant change from baseline in vital signs sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Pfizer Clinical Research Unit - New Haven status: RECRUITING city: New Haven state: Connecticut zip: 06511 country: United States lat: 41.30815 lon: -72.92816 hasResults: False
nctId: NCT06275828 id: PoliceGeneralHospiral briefTitle: The Effect of Perioperative and Postoperative Music Reduces Pain Perception After Anterior Cruciate Ligament Reconstruction overallStatus: ACTIVE_NOT_RECRUITING date: 2022-12-15 date: 2023-07-31 date: 2024-02-20 date: 2024-02-23 date: 2024-02-23 name: Police General Hospital, Thailand class: OTHER briefSummary: study the effect of music therapy in pre-operative and post operative period and measure the out come by the visual analog scale (pain score) and analgesic drug use such as morphine and the anxiety score conditions: Anterior Cruciate Ligament Tear studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: TRIPLE whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 46 type: ACTUAL name: slow beat mesic listening by headphone measure: visual analog scale measure: analgesic drug use measure: Amsterdam Preoperative Anxiety and Information Scale sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Police General Hospital city: Bangkok state: Pathuwam zip: 10330 country: Thailand lat: 13.75398 lon: 100.50144 hasResults: False
nctId: NCT06275815 id: R01DC020958 type: NIH link: https://reporter.nih.gov/quickSearch/R01DC020958 briefTitle: Promoting Caregiver Implementation of an Effective Early Learning Intervention overallStatus: RECRUITING date: 2024-04-10 date: 2028-07-31 date: 2028-07-31 date: 2024-02-23 date: 2024-04-12 name: Ohio State University class: OTHER name: Nationwide Children's Hospital briefSummary: The goal of this study is to examine the impact of a caregiver-implemented shared reading program, Sit Together and Read (STAR), on children ages 4 to 5 with developmental language disorder. The main questions it aims to answer are:
Researchers will determine the short term and long term impacts of STAR compared to the control group. Researchers will compare the three STAR conditions to see if the rewards or encouragement helped parents to follow through with completing more STAR sessions. conditions: Developmental Language Disorder conditions: Reading; Difficult studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: DOUBLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 320 type: ESTIMATED name: Sit Together and Read (STAR) name: Monetary Reward name: Text Encouragement measure: Preschool Word and Print Awareness (PWPA) measure: Phonological Awareness Literacy Screening (PALS): Alphabet Knowledge and Name Writing measure: The Reading House (THR) measure: Woodcock Johnson Test of Achievement- IV (WJ-IV): Word Attack and Letter-Word Identification measure: Woodcock Johnson Test of Achievement- IV (WJ-IV): Spelling, Passage Comprehension sex: ALL minimumAge: 48 Months maximumAge: 66 Months stdAges: CHILD facility: Schoenbaum Family Center; Crane Center for Early Childhood Research and Policy status: RECRUITING city: Columbus state: Ohio zip: 43201 country: United States name: Jennifer M Bostic, MA role: CONTACT phone: 614-292-5715 email: bostic.18@osu.edu name: Laura M Justice, PhD role: PRINCIPAL_INVESTIGATOR name: Rebecca Dore, PhD role: SUB_INVESTIGATOR name: Hui Jiang, PhD role: SUB_INVESTIGATOR lat: 39.96118 lon: -82.99879 facility: Nationwide Children's Hospital status: RECRUITING city: Columbus state: Ohio zip: 43205 country: United States name: Jamie B Boster, PhD role: CONTACT phone: 614-722-8756 email: jamie.boster@nationwidechildrens.org name: Jamie B Boster, PhD, CCC-SLP role: PRINCIPAL_INVESTIGATOR lat: 39.96118 lon: -82.99879 hasResults: False
nctId: NCT06275802 id: 22-5.1T/2 briefTitle: The Effect of Nutrition Education Interventions for Adolescents overallStatus: RECRUITING date: 2022-06-06 date: 2023-12-30 date: 2024-06-30 date: 2024-02-23 date: 2024-02-23 name: Ege University class: OTHER briefSummary: The aim of this study is to determine the effect of nutrition education on nutritional literacy, nutritional status, eating habits and eating behavior in high school students. The research will be conducted in six high schools, three of which are intervention schools and three of which are control schools It is planned that a total of 1000 students will be included in the study from the intervention school and 1000 students from the control school. At the beginning of the study (June 2022), an introductory form (sociodemographic characteristics, body image (Stunkart scale), dietary habits, knowledge about weight status) was applied to all students. Adolescent Nutrition Literacy Scale (ANLS), Instrument of Nutrition Literacy, Mediterranean Diet Quality Index (KID-MED), Eating Attitudes Test 26 (EAT-26), International Physical Activity Questionnaire Short Form (IPAQ) were applied, anthropometric measurements and three-day food consumption records were taken. During the study, nutrition initiatives consisting of 8 modules will be made to the intervention schools. Control schools will not be interfered with during this period.At the end of the study, the procedures applied at the beginning will be repeated. conditions: Nutrition, Healthy conditions: Nutrition Disorders in Adolescence conditions: Eating Habit conditions: Eating Behavior conditions: Body Image studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 1000 type: ESTIMATED name: Nutrition Education name: nutritional status, eating habits measure: nutrition literacy measure: Mediterranean Diet Quality Index (KID-MED) measure: Eating Attitudes Test 26 (EAT-26) measure: weight and height measurement measure: waist circumference measurement measure: Food Consumption Record measure: International Physical Activity Questionnaire (IPAQ- Short Form) sex: ALL maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Menemen District Directorate of National Education status: RECRUITING city: İzmir country: Turkey name: Sibel ÖZER role: CONTACT phone: (0232) 832 26 29 lat: 38.41273 lon: 27.13838 hasResults: False
nctId: NCT06275789 id: 2023-268 briefTitle: Mix of Demineralized Freeze-Dried Bone Allograft and Deproteinized Bovine Bone Mineral: a Possible Solution for Alveolar Ridge Preservation? overallStatus: RECRUITING date: 2024-01-26 date: 2025-06 date: 2025-06 date: 2024-02-23 date: 2024-04-09 name: Nova Southeastern University class: OTHER name: Geistlich Pharma AG name: ZimVie briefSummary: The purpose of the study is to compare a new grafting material for alveolar ridge preservation to a commonly used and well studied material. Alveolar ridge dimensions as well as histology will be compared. conditions: Alveolar Ridge Preservation conditions: Dental Extraction conditions: Bone Graft studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 30 type: ESTIMATED name: Alveolar ridge preservation measure: changes in horizontal dimensions of the alveolar ridge measure: changes in vertical dimensions of the alveolar ridge measure: vital bone percentage measure: thickness of the buccal plate in mm and its influence on the ridge dimension measure: the thickness of the lingual plate in mm and its influence on the ridge dimension measure: the thickness of the overlying buccal soft tissue in mm and its influence on the ridge dimension measure: the position of extraction site (maxilla vs. mandible) and its influence on the ridge dimension measure: # of cigarettes and its influence on the ridge dimension measure: oral hygiene using the plaque index and its influence on the ridge dimension sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Nova Southeastern University status: RECRUITING city: Fort Lauderdale state: Florida zip: 33328 country: United States name: Saynur Vardar-Sengul, DDS, PhD role: CONTACT phone: 954-262-1815 email: svardarsengul@nova.edu lat: 26.12231 lon: -80.14338 hasResults: False
nctId: NCT06275776 id: OC-2022-005 briefTitle: HIP-STITCH (Wound Recovery After THA) overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2028-03-01 date: 2028-05-01 date: 2024-02-23 date: 2024-03-05 name: Reinier Haga Orthopedisch Centrum class: OTHER briefSummary: This prospective randomised trial will investigate the effect of four different suturing techniques (Monocryl, Vicryl Rapide with Indermil skin glue, Dermabond Prineo, and Stryker Zip) on the amount of aberrant wound recovery within 14 days after total hip arthroplasty at the RHOC in Zoetermeer, The Netherlands.
Hypothesis: Monocryl sutures give the highest amount of aberrant wound recovery within fourteen days after primary THA. conditions: Wound Healing Disturbance of studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Test subjects are randomised into one of four study arms. Each study arm corresponds with one of the suturing techniques that are going to be used to close the superficial skin after Total Hip Arthroplasty. primaryPurpose: TREATMENT masking: SINGLE maskingDescription: No one in this study can reasonably be blinded for the suturing technique during the duration of the study, since the suturing techniques differ substantially in shape, appearance and size. The only blinding in this study is the blinding of the outcome assessor to data of the test subjects. The assessor will only see the photographs of the wound/plaster, and the moment on which the photograph was taken. Additional information on the test subject, such as age, comorbidities, et cetera, will be withheld from the assessor. whoMasked: OUTCOMES_ASSESSOR count: 236 type: ESTIMATED name: Ethicon Monocryl Smooth Suture name: Ethicon Vicryl Rapide Braided Suture name: Flexifuze Indermil Topical Skin Adhesive name: Dermabond Prineo Skin Closure System name: Stryker Zip Skin Closure System measure: Number of Participants with Aberrant Wound Recovery measure: Number of Participants with Superficial or Deep Wound Infection measure: Patient reported outcome measure: Satisfaction scores suturing method (Questionnaire) measure: Costs measure: Patient reported outcome measure: Score of Self-removal of the suturing technique (Questionnaire) measure: Patient reported outcome measure: Number of Participants with Other postoperative symptoms measure: Number and Type of Complications measure: Number of Visits to a Healthcare Professional sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Reinier Haga Orthopedisch Centrum city: Zoetermeer state: Zuid Holland zip: 2725NA country: Netherlands name: Brechtje Hesseling, Msc role: CONTACT phone: 003179-2065595 email: onderzoek@rhoc.nl name: Nina MC Mathijssen, Dr. role: CONTACT phone: 003179-2065595 email: onderzoek@rhoc.nl lat: 52.0575 lon: 4.49306 hasResults: False
nctId: NCT06275750 id: CEI 175/23 briefTitle: Non-surgical Spinal Decompression in Patients With Chronic Low Back Pain overallStatus: COMPLETED date: 2023-08-21 date: 2023-11-29 date: 2024-01-11 date: 2024-02-23 date: 2024-02-23 name: Hospital Civil de Guadalajara class: OTHER briefSummary: The goal of this quasi-experimental trial was to evaluate the effects of non-surgical spinal decompression on disability and pain in patients with chronic low back pain and sciatica throughout a two-month follow-up, and to analyze the relationship between demographic factors and clinical outcomes after a program of non-surgical spinal decompression.