hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06298851 id: E-10840098-772.02-2026 briefTitle: Comparative Effects of Lower Body Quadrant Neural Mobilization and Stretching in Collegiate Football Players overallStatus: NOT_YET_RECRUITING date: 2024-03-08 date: 2024-03-25 date: 2024-03-31 date: 2024-03-07 date: 2024-03-07 name: Istanbul Medipol University Hospital class: OTHER briefSummary: Neural mobilizations (NM) are defined as interventions that aim to directly or indirectly affect neural structures or surrounding tissue through manual techniques or exercise. Neural mobilizations have been studied in both patients and healthy populations. In the study, individuals in the amateur football team will be divided into three groups and will be given pre-training warm-up periods, including neural mobilization, dynamic and static stretching.After the warm-up period, its effect on flexibility and performance will be examined and compared. conditions: Sports Physical Therapy conditions: Stretch conditions: Stretch Injury studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: Neural Mobilization Group (NMG) name: Dynamic Stretching Group (DSG) name: Static Stretching Group (SSG) measure: Straight Leg Raise Test measure: Y Balance Test measure: One-Leg Forward Jump Test measure: T Test measure: BlazePod Reaction Time Determination Test sex: ALL minimumAge: 18 Years maximumAge: 25 Years stdAges: ADULT facility: Istanbul Medipol University city: Istanbul zip: 34820 country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06298838 id: XEOS study briefTitle: High-resolution Intra-operative PSMA PET-CT in Prostate Cancer overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-03 date: 2025-03 date: 2024-03-07 date: 2024-03-07 name: IRCCS San Raffaele class: OTHER briefSummary: This is a Single-center, diagnostic open-label prospective, pilot study in a total of 10 patients affected by Prostate cancer (PCa) with a risk of lymph node invasion (LNI) higher than 5% and candidates for a robot-assisted radical prostatectomy (RARP) with an extended pelvic lymph node dissection (ePLND) .
The aim of the trial is to evaluate the feasibility and accuracy and clinical value of a novel high-resolution perioperative PET-CT-scan for intraoperative margin and lymph node invasion assessment, after 18F-PSMA injection, using histopathology as the gold standard. conditions: Prostate Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 10 type: ESTIMATED name: AURA10® Specimen PET/CT imager measure: To investigate the performance characteristics (sensitivity and specificity) of a novel high-resolution perioperative PET-CT-scan for intraoperative margins and lymph node invasion assessment after 18F-PSMA using histopathology as the gold standard measure: Reporting positive lymph nodes detection rate at intraoperative imaging after 18-PSMA injection sex: MALE minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06298825 id: KY2024-148 briefTitle: S-ADHF：Sarcopenia in Patients With ADHF acronym: S-ADHF overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-12-01 date: 2026-06-01 date: 2024-03-07 date: 2024-03-12 name: Guangdong Provincial People's Hospital class: OTHER briefSummary: This is a prospective, multi-center, investigator-initiated observational cohort study. Enrollment with a minimum of of 195 cases each for patients with and without sarcopenia. Each patient is followed up for 6 month, 1 year, 2 years or until the occurrence of death.This study will examine the correlation between sarcopenia and prognosis in different subgroups of patients, and explore the additive effect of different comorbidities and sarcopenia on prognosis in patients with acute decompensated heart failure. conditions: Acute Decompensated Heart Failure studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 500 type: ESTIMATED measure: All-cause mortality measure: All-cause mortality measure: Cardiovascular mortality measure: All-cause hospitalisation measure: HF hospitalisation measure: The frequency and length of hospitalization of patient readmitted measure: Survival time from enrollment to death of deceased patients sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Huan Ma city: Guangdong country: China name: Huan Ma, PhD role: CONTACT phone: +86 15078755932 email: mahuandoctor@163.com hasResults: False
nctId: NCT06298812 id: Protocol Rev 0 11July2023 briefTitle: REFLECT Scoliosis System Post Approval Study overallStatus: NOT_YET_RECRUITING date: 2024-03-31 date: 2027-03-31 date: 2032-03-31 date: 2024-03-07 date: 2024-03-07 name: Globus Medical Inc class: INDUSTRY briefSummary: The purpose of this multi-center, prospective, single-arm registry Post-Approval Study (PAS) is to evaluate the radiographic and clinical outcomes of 100 patients with idiopathic scoliosis treated with the REFLECT™ Scoliosis Correction System, as a condition of HDE approval conditions: Idiopathic Scoliosis studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Patients treated with the REFLECT Scoliosis Correction System primaryPurpose: TREATMENT masking: NONE count: 100 type: ESTIMATED name: REFLECT Scoliosis Correction System measure: Primary Probable Benefit measure: Primary Safety measure: Curve progression measure: Device integrity measure: Composite endpoint analysis measure: Failure analysis measure: SRS score sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Mayo Clinic city: Rochester state: Minnesota zip: 55905 country: United States name: Jana Robinson role: CONTACT name: Noelle Larson, MD role: PRINCIPAL_INVESTIGATOR lat: 44.02163 lon: -92.4699 hasResults: False
nctId: NCT06298799 id: GEN-GE-001-IL briefTitle: GENETIC VARIABILITY TO GLP1 TREATMENT acronym: GLP1 treatment overallStatus: RECRUITING date: 2023-10-01 date: 2025-01-01 date: 2025-01-01 date: 2024-03-07 date: 2024-03-07 name: GENGE class: OTHER briefSummary: The goal of this retrospective study is to assess whether a selection of genetic variants may allow us to identify individuals who will have a satisfactory response after GLP-1 treatment in terms of weight loss, sugar level reduction, and adverse events.
A. Type 2 Diabetic participants cohort B. Healthy participants cohort primaryPurpose: OTHER masking: NONE maskingDescription: no masking count: 400 type: ESTIMATED name: DNA Sequencing and Analysis name: differential expression analysis with RNA-sequencing (RNA seq) experiments measure: Genetic variants and miRNA expressions associated with changes in BMI. measure: Genetic variants and miRNA expressions associated with changes in A1c. measure: Genetic variants and miRNA expressions associated with side effects. measure: Demographic parameters that affect GLP1 AG therapy. sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Rambem medical center status: RECRUITING city: Haifa country: Israel name: Irit Hochberg, MD role: PRINCIPAL_INVESTIGATOR lat: 32.81841 lon: 34.9885 hasResults: False
nctId: NCT06298786 id: 6MIMATE012 briefTitle: Validation and Evaluation of the Mastication Function in Adults: The Functional Six-minute Mastication Test (F-6MMT). acronym: F-6MMT overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-06 date: 2024-09 date: 2024-03-07 date: 2024-03-13 name: Fundació Universitària del Bages class: OTHER name: Hospital Universitari Sagrat Cor name: Universitat Internacional de Catalunya name: Clinicas Dr. Emilio López Jiménez briefSummary: Temporomandibular Disorders (TMD) encompass various conditions that affect the temporomandibular joint and associated tissues, often causing or being associated with other symptoms such as jaw pain, myofascial pain, neck pain, and headaches. TMDs are classified according to the DC/TMD instrument in which the joint and pain axes are evaluated. However, there is no evaluation of mandibular function, and TMDs can result in a decrease in jaw strength and resistance. This leads to an increase in the chewing fatigue. Reliable and time-effective diagnostic methods for evaluating masticatory function are crucial in the clinical setting because of the high prevalence of TMD. Chewing efficiency is essential for food preparation and nutrient absorption, and muscle fatigue is a common problem affecting chewing ability. Despite this, there is a lack of validated tests to evaluate chewing fatigue in patients with TMD, which makes its consideration unnoticed in clinical practice.
The modified six-minute functional chewing test (F-6MMT) was proposed as a tool to evaluate chewing ability and fatigue in patients with TMD. This test is an adaptation of a previously designed test in which subjects with mitochondrial pathology were evaluated; however, the subjects were not instructed to perform functional chewing during the test. In this version, modifications are added so that the test is as functional as possible, allowing chewing to be evaluated in a standardized way, and cut-off points established between healthy subjects and subjects with TMD in terms of chewing capacity in general and fatigue in particular. This study will follow standardized reporting guidelines and recruit participants from diverse clinical settings. conditions: Mastication Disorder conditions: Fatigue conditions: Temporomandibular Disorder conditions: Orofacial Pain conditions: Chewing Problem studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: CROSS_SECTIONAL count: 400 type: ESTIMATED name: Functional 6-minute mastication test measure: Fatigue measure: Self-reported Pain measure: Pain-related TMD diagnosis measure: Self-reported daily fatigue measure: Pain pressure threshold (PPT) measure: Taste of the gum measure: Difficulty in breaking the gum at the beginning of the F-6MMT measure: Preferred side when chewing during the F-6MMT measure: Kinesiofobia related to TMD measure: Health status measure: Comorbidities sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Universitat de Manresa city: Manresa state: Barcelona zip: 08242 country: Spain name: Jordi Padrós, Mr role: CONTACT phone: 613040826 email: jpadros@umanresa.cat name: Jordi Padros-Augé, PhDS role: PRINCIPAL_INVESTIGATOR name: Arnau Cerdà-Ribó, PT role: PRINCIPAL_INVESTIGATOR lat: 41.72815 lon: 1.82399 facility: Universitat Internacional de Catalunya city: Barcelona zip: 08017 country: Spain name: Jordi Tomás-Aliberas, PhD role: CONTACT phone: +34932541800 email: jtomas@uic.es lat: 41.38879 lon: 2.15899 facility: Hospital QuirónSalud Sagrado Corazón city: Barcelona zip: 08029 country: Spain name: Cristian Justribó, Mr role: CONTACT phone: +34672057031 email: cjustribom@uao.es name: Cristian Justribó-Manion, PhDS role: PRINCIPAL_INVESTIGATOR name: José J Bara Casaus, PhD role: PRINCIPAL_INVESTIGATOR lat: 41.38879 lon: 2.15899 facility: Clínicas Dr. Emilio López Jiménez city: Jaén zip: 23280 country: Spain name: Emilio López-Jiménez, PhD role: CONTACT phone: 665842389 email: ddnariz@gmail.com lat: 37.76922 lon: -3.79028 hasResults: False
nctId: NCT06298773 id: 6127 briefTitle: Spatial Profile of Tumors acronym: PROST overallStatus: NOT_YET_RECRUITING date: 2024-03-05 date: 2026-09-30 date: 2028-12-30 date: 2024-03-07 date: 2024-03-07 name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS class: OTHER briefSummary: The research project focuses on analyzing the spatial organization of cells within various solid tumors, utilizing advanced technologies enabling in-depth multi-parametric analysis of tumor and immune cells. The primary objective is to understand the spatial distribution of cellular subpopulations within each type of tumor, while secondary objectives include correlating these data with clinical aspects and identifying potential therapeutic targets. The study involves 1000 patients with primary or metastatic tumors and spans a duration of 5 years, from 2024 to 2028. No experimental treatments are planned; rather, only spatial imaging analyses with multiple markers will be conducted. Data analysis involves descriptive statistical methods and hypothesis testing to generate hypotheses for subsequent studies. The analyses will be performed using SPSS® version 21.0 software for Windows®. conditions: Solid Tumors studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 1000 type: ESTIMATED name: Spatial analysis of paraffin samples from solid tumors measure: Spatial analysis of cancer cells measure: Comparison of clinical data measure: Identification of therapeutic targets sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fondazione Policlinico Universitario Agostino Gemelli IRCCS city: Rome state: RM zip: 00168 country: Italy name: Alessandro Sgambato role: CONTACT phone: +390630154914 email: alessandro.sgambato@policlinicogemelli.it name: Alessandro Sgambato role: PRINCIPAL_INVESTIGATOR lat: 41.89193 lon: 12.51133 hasResults: False
nctId: NCT06298760 id: çörekotu refleksoloji briefTitle: The Effect of Reflexology and Knee Massage With Black Cumin Oil on Pain and Fatigue overallStatus: COMPLETED date: 2019-06-19 date: 2020-02-19 date: 2020-04-19 date: 2024-03-07 date: 2024-03-12 name: Erzurum Technical University class: OTHER briefSummary: In this study, black cumin extract oil was used in elderly individuals with Knee Osteoarthritis (OA). The effects of foot reflexology and knee massage on pain and fatigue symptoms. It is aimed to examine and research which of these two applications is more effective.The study, planned as a randomized controlled experimental study, included a total of 150 participants.
The data consists of participants who receive outpatient treatment in the Physical Therapy and Rehabilitation Unit at a university hospital, are over 65 years old, and have no problems with their perception after the Mini Mental Test. After randomization, participants were divided into five groups, with 30 participants in each group. Groups; It consisted of 1) Reflexology with Black Cumin, 2) Placebo Reflexology, 3) Knee Massage with Black Cumin, 4) Placebo Knee Massage and 5) Control groups. conditions: Knee Osteoarthritis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: After randomization, participants were divided into 30 participants in each group.
were divided into five groups:Groups; It consisted of 1) Reflexology with Black Cumin, 2) Placebo Reflexology, 3) Knee Massage with Black Cumin, 4) Placebo Knee Massage and 5) Control groups. "Patient Information Form", "Kellgren and Lawrence", "Pain Visual Analog Scale (A-VAS)", "Fatigue Severity Scale and Western Ontario and McMaster Universities Osteoarthritis Index "WOMAC" were applied to the participants. Participants in the application groups were administered once a week for 6 weeks. The session lasted 30 minutes. The control group was allowed to continue routine treatment and care without any intervention. Data were collected by applying questionnaires to the participants in the 1st and 6th weeks. primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 150 type: ACTUAL name: Knee Massage With Black Cumin Oil Group: name: Foot Reflexology Group With Black Cumin Oil name: placebo group measure: Pain Score measure: fatigue severity sex: ALL minimumAge: 65 Years maximumAge: 90 Years stdAges: OLDER_ADULT facility: Ercan Bakır city: Erzurum state: Yakutiye country: Turkey lat: 39.90861 lon: 41.27694 hasResults: False
nctId: NCT06298747 id: Cervical root PRF briefTitle: Ultrasound-guided Selective Cervical Root Pulsed Radiofrequency Therapy in Patients With Cervical Radicular Pain acronym: pulsedrf overallStatus: COMPLETED date: 2022-11-01 date: 2023-07-01 date: 2023-07-02 date: 2024-03-07 date: 2024-03-15 name: Diskapi Teaching and Research Hospital class: OTHER briefSummary: Chronic cervical pain is a common disorder with a prevalence of approximately 35% in adults. Cervical radicular pain is defined as radiating pain in the upper limb caused by compression or inflammation of the nerve roots ascending from the intervertebral foramen to the spinal cord, due to disc herniation or spinal stenosis. C7 and C6 are the two most commonly affected nerve roots. Various treatment modalities are available, including oral medications, physiotherapy, and epidural steroid injections. However, chronic and persistent pain that develops as a result of some patients not responding to these treatments. Ultrasound-guided selective cervical nerve root block and pulsed radiofrequency are interventional treatments used in patients with radicular cervical pain unresponsive to conservative treatments. Pulsed radiofrequency (PRF) treatment of peripheral nerves may provide long-term pain relief in patients with short-term pain relief with a local anesthetic block. Studies have shown the effectiveness of PRF therapy applied to selective cervical nerve roots in relieving cervical radicular pain. conditions: Cervical Pain studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: RETROSPECTIVE count: 45 type: ACTUAL name: Selective cervical nerve root pulsed radiofrequency measure: VAS measure: Neck Disability Index (NDI) measure: Douleur Neuropathique 4 Questions (DN4) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ankara Etlik City Hospital city: Ankara country: Turkey lat: 39.91987 lon: 32.85427 hasResults: False
nctId: NCT06298734 id: 23-712 briefTitle: Exercise and Diet Interventions During Immunotherapy in Melanoma Patients overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2025-03-31 date: 2026-03-31 date: 2024-03-07 date: 2024-03-07 name: Dana-Farber Cancer Institute class: OTHER name: World Cancer Research Fund International briefSummary: The purpose of this study is to determine whether high-intensity exercise and high-fiber diet are feasible and improve various health outcomes among participants with advanced melanoma receiving immunotherapy.
* Attention Control (AC) conditions: Melanoma (Skin) conditions: Skin Cancer conditions: Advanced Melanoma studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 40 type: ESTIMATED name: Exercise Program name: Diet Program measure: Change in Gut Microbiome Diversity measure: Change in Systemic Immune Function measure: Change in Cardiopulmonary Fitness measure: Change in Short Physical Performance Battery (SPPB) measure: Change in Percent Body Fat measure: Change in Lean mass measure: Change in Hip circumference measure: Change in Waist circumference measure: Change in Health-Related Quality of life (EORTC-QLQ C30) measure: Change in MDASI-Immunotherapy Questionnaire Score measure: Change in Anxiety (HADS) measure: Change in Depression (HADS) measure: Change in Sleep Quality (PSQI) measure: Proportion of Participants Completing the Exercise Intervention Sessions sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Dana-Farber Cancer Institute city: Boston state: Massachusetts zip: 02215 country: United States lat: 42.35843 lon: -71.05977 hasResults: False
nctId: NCT06298721 id: 23-885 briefTitle: Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes overallStatus: RECRUITING date: 2024-03-12 date: 2027-03 date: 2027-03 date: 2024-03-07 date: 2024-04-17 name: The Cleveland Clinic class: OTHER name: American Association of Hip and Knee Surgeons briefSummary: This study is a randomized controlled trial to assess whether the implementation of a TKA Personalized Outcome Prediction Tool to set expectation, in addition to targeted interventions to address patients with poor baseline mental health and poor physical function, improves satisfaction at 1-year (when compared to standard of care). conditions: Knee Osteoarthritis conditions: Knee Arthropathy conditions: Surgery studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 300 type: ESTIMATED name: Personalized outcome prediction tool + targeted interventions name: Standard of Care TKA measure: Satisfaction at 1 year sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Cleveland Clinic Foundation status: RECRUITING city: Cleveland state: Ohio zip: 44195 country: United States name: Shujaa T Khan, MD role: CONTACT phone: 419-965-8274 email: khans34@ccf.org lat: 41.4995 lon: -81.69541 hasResults: False
nctId: NCT06298708 id: PED-2566-0634 briefTitle: Immunogenicity and Safety of Inactivated and Live-attenuated HAV Vaccine Among Thai Healthy Children and Adolescents acronym: HAV-RCT overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-03 date: 2025-06 date: 2024-03-07 date: 2024-03-08 name: Chiang Mai University class: OTHER name: Faculty of Medicine, Chiang Mai University briefSummary: Hepatitis A virus (HAV) vaccine is an effective strategy to prevent natural HAV infection. In Thailand, there are 2 types of HAV vaccine available, including inactivated HAV vaccine and live-attenuated HAV vaccine. This study aims to compare the immunogenicity and safety of inactivated and lived-attenuated HAV vaccine among Thai healthy children and adolescents age 18 months to 18 years. conditions: HAV conditions: Hepatitis A conditions: Hep A conditions: Vaccine-Preventable Diseases studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 120 type: ESTIMATED name: Mevac-A vaccine name: Havrix 720 Junior measure: Anti-HAV immunoglobulin G (IgG) seroconversion rate measure: Geometric mean concentration (GMC) of anti-HAV IgG level sex: ALL minimumAge: 18 Months maximumAge: 18 Years stdAges: CHILD stdAges: ADULT hasResults: False