nctId: NCT06371131 id: PONV of Thyroid Surgery briefTitle: Effect of Stellate Ganglion Block on Postoperative Nausea and Vomiting overallStatus: RECRUITING date: 2023-04-17 date: 2024-05-30 date: 2024-08-30 date: 2024-04-17 date: 2024-04-26 name: The Second Affiliated Hospital of Chongqing Medical University class: OTHER briefSummary: Postoperative nausea and vomiting is one of the most common postoperative complications second only to postoperative pain. Studies have reported that without any antiemetic prevention treatment, the overall incidence of PONV in surgical operations is up to 20-30%, and the incidence of PONV in high-risk patients such as thyroid surgery is even up to 70-80%. PONV not only increased discomfort and prolonged hospital stay; Severe cases can lead to wound dehysis, acid-base imbalance, water and electrolyte metabolism disorders, seriously affect the prognosis of patients. Although various prevention and treatment measures have been adopted in clinical practice, it still cannot be completely eliminated. Therefore, postoperative nausea and vomiting of thyroid is still a concern in clinical anesthesia work, so it is urgent to explore more simple and effective measures to prevent thyroid PONV. SGB is the injection of local anesthetics into loose connective tissue containing stellate ganglion. It has a clear effect on postoperative analgesia of thyroid surgery, and can play a certain role in preventing thyroid PONV by reducing the application of perioperative opioids. Few studies have reported that the incidence of PONV can be significantly reduced after the application of SGB in patients with thyroid surgery, which provides a certain basis for the prevention of thyroid PONV. Therefore, this study aims to explore the effect of right stellate ganglion block on preventing postoperative nausea and vomiting of thyroid, and to explore the possible mechanism of action. conditions: Stellate Ganglion Block conditions: Thyroid Surgery conditions: Postoperative Nausea and Vomiting studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Experimental group: right stellate ganglion block 30 minutes before anesthesia induction.Control group: No treatment was given 30minutes before anesthesia induction.Data was recorded at the corresponding time points. primaryPurpose: HEALTH_SERVICES_RESEARCH masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 200 type: ESTIMATED name: Right -stellate ganglion block measure: Incidence of Postoperative nausea and vomiting measure: Incidence of Postoperative nausea and vomiting during preemptive analgesia measure: Intensity of nausea and vomiting during preemptive analgesia measure: Intensity of nausea and vomiting during hospitalization measure: Hemodynamic parameters after preemptive analgesia measure: Postoperative pain intensity measure: Recovery of gastrointestinal function measure: Sleep quality measure: Satisfaction score and postoperative analgesia satisfaction score sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Second Affiliated Hospital of Chongqing Medical University status: RECRUITING city: Chongqing state: Chongqing zip: 400000 country: China name: ling Dan, BD role: CONTACT phone: 86 13983072922 email: 302069@hospital.cqmu.edu.cn lat: 29.56278 lon: 106.55278 hasResults: False