hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06359743 id: 271/7 briefTitle: Ultrasound Guided QLB Versus Laparoscopic Superior Hypogastric Plexus Block for Postoperative Analgesia After Laparoscopic Hysterectomy overallStatus: ACTIVE_NOT_RECRUITING date: 2024-04-01 date: 2024-08-01 date: 2024-09-01 date: 2024-04-11 date: 2024-04-11 name: Zagazig University class: OTHER_GOV briefSummary: Pain following laparoscopic hysterectomy may interfere with early ambulation, discharge of patient from hospital and interfere with enhanced recovery with more opioid consumption. Most of methods for postoperative pain depend on the use of high doses of opioids with more side effects such as nausea, vomiting, respiratory center depression, delay bowel motility and hemodynamics instability. To decrease of opioid consumption in postoperative pain management as well as related side effects, previous studies showed that quadratus lumborum block or superior hypogastric plexus block (SHPB) had shown promising success in management of postoperative pain in patients undergoing laparoscopic hysterectomy. The present study will be conducted to compare of ultrasound guided QL block and laparoscopic superior hypogastric plexus block as a part of multimodal analgesia may allow adequate analgesia and decrease the overall use of opioids and allow patient enhanced recovery. conditions: Post Hysterectomy Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 34 type: ESTIMATED name: Quadratus Lamborum versus superior hypogatric measure: Opioid consumption decrease sex: FEMALE minimumAge: 45 Years maximumAge: 60 Years stdAges: ADULT facility: Faculty of medicine, Zagazig university city: Zagazig state: Sharkia country: Egypt lat: 30.58768 lon: 31.502 hasResults: False
nctId: NCT06359730 id: 253/26-March-2024 briefTitle: Incidence and Risk Factors of Low Anterior Resection Syndrome overallStatus: COMPLETED date: 2017-12-01 date: 2022-12-01 date: 2022-12-01 date: 2024-04-11 date: 2024-04-11 name: Zagazig University class: OTHER_GOV briefSummary: Sphincter sparing surgery is oftentimes associated with bowel dysfunction complaints, namely the low anterior resection syndrome (LARS). The LARS questionnaire is widely used to assess this syndrome.
With advances in colorectal surgery, sparing sphincter surgeries are gaining popularity. But symptoms after surgery can affect the quality of life which has psychomotor effects. Low anterior resection syndrome score is a worldwide known questionnaire. Many countries have accredited validation and translation of this questionnaire, but to our knowledge; it is the first time in Egypt. conditions: Colorectal Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 120 type: ACTUAL name: LARS score questionnaire measure: age measure: sex measure: medical disease measure: site of tumor measure: neoadjuvant therapy measure: site of anastmosis measure: type of meso-rectal excision measure: adjuvant therapy measure: type of surgery measure: type of anastmosis measure: LARS score sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Zagazig University Hospitals city: Zagazig zip: 44519 country: Egypt lat: 30.58768 lon: 31.502 hasResults: False
nctId: NCT06359717 id: ZU-10490 briefTitle: Prospective Validation of PSMA-RADS acronym: PSMA-RADS overallStatus: ACTIVE_NOT_RECRUITING date: 2023-01-01 date: 2024-04-10 date: 2024-04-20 date: 2024-04-11 date: 2024-04-11 name: Zagazig University class: OTHER_GOV briefSummary: This is a prospective, multicenter study aimed at evaluating the diagnostic accuracy and reliability of the Prostate-Specific Membrane Antigen Reporting and Data System (PSMA-RADS) version 1.0 in detecting prostate cancer using 68Ga-PSMA-11 PET/CT imaging. The study also compared the performance of PSMA-RADS v1.0 with the updated version 2.0.
* The study aimed to validate the diagnostic utility of PSMA-RADS v1.0 and compare it to the updated v2.0. conditions: Cancer Prostate studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 208 type: ESTIMATED measure: Diagnostic Accuracy of PSMA-RADS v1.0 and v2.0 measure: Inter-rater Agreement of PSMA-RADS v1.0 and v2.0 sex: MALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mohammad Abd Alkhalik Basha city: Zagazig state: Select zip: 44631 country: Egypt lat: 30.58768 lon: 31.502 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2024-01-21 uploadDate: 2024-04-05T07:38 filename: Prot_SAP_000.pdf size: 692777 hasResults: False
nctId: NCT06359704 id: kevinszc briefTitle: Intervention for Emotions in Caregivers of Dementia overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2024-10-01 date: 2025-02-01 date: 2024-04-11 date: 2024-04-12 name: The University of Hong Kong class: OTHER briefSummary: This study aims to evaluate the effectiveness of a 6-week Caregivers Of dementia Processing Emotions (COPE) program using the integrative therapy to reduce EE (primary outcome) in family caregiver of PLwD to alleviate the caregivers' depression, improve social dynamic with the PLwD, and mitigate the perceived stress from BPSD (secondary outcomes). conditions: BPSD conditions: Expressed Emotion conditions: Depressive Symptoms studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: controlled arm with waitlist treatment primaryPurpose: SUPPORTIVE_CARE masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 56 type: ESTIMATED name: Caregivers Of dementia Processing Emotions (COPE) program measure: Expressed emotions measure: depressive symptoms measure: social dynamics measure: BPSD sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06359691 id: 4UH3HL154302 type: NIH link: https://reporter.nih.gov/quickSearch/4UH3HL154302 id: 4UH3HL154302 type: NIH link: https://reporter.nih.gov/quickSearch/4UH3HL154302 briefTitle: Multi-ethnic Multi-level Strategies and Behavioral Economics to Eliminate Hypertension Disparities in Los Angeles County overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2027-06 date: 2027-06 date: 2024-04-11 date: 2024-04-12 name: University of California, Los Angeles class: OTHER name: National Heart, Lung, and Blood Institute (NHLBI) briefSummary: The goal of the study is to promote equitable hypertension (HTN) management across the diverse patient population found in Los Angeles County Department of Health Services (LAC DHS) clinics.
LAC DHS clinics will be randomly assigned to one of three study conditions: 1) provider-focused outreach, 2) patient-focused outreach, and 3) usual outreach. The study will occur across 3 years with patient- and provider-focused outreach occurring in Year 1 and 2. In Year 3, study initiated patient- and provider-focused outreach will stop, and clinic use of patient- and provider-focused outreach practices will be observed by the study team.
Provider-focused outreach includes increasing cultural awareness of factors that hinder and support blood pressure control, increasing access to blood pressure medications, and providing blood pressure management education. Patient-focused outreach includes using culturally sensitive educational materials and reminders to improve patient understanding of blood pressure, education on how to manage the condition, and increasing awareness of available blood pressure management resources. Clinics assigned to the usual outreach condition will operate as per usual in Year 1 but will receive patient- and provider-focused outreach in Year 2. conditions: Hypertension studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Three-armed crossover trial design to test effectiveness and sustainment of our implementation strategies across LAC DHS clinics and the communities they serve. primaryPurpose: HEALTH_SERVICES_RESEARCH masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 540 type: ESTIMATED name: Patient-focused strategies name: Provider-focused strategies name: Patient- and provider-focused strategies measure: Overall provider adoption of evidence based practices measure: Provider/Care Team EBP Acceptability, Appropriateness, Feasibility measure: Blood Pressure (BP) Control sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Olive View-UCLA Medical Center city: Sylmar state: California zip: 91342 country: United States name: Soma Wali, MD role: CONTACT phone: 747-210-3205 email: swali@dhs.lacounty.gov lat: 34.30778 lon: -118.44925 hasResults: False
nctId: NCT06359678 id: NL85844.015.23 briefTitle: The Northstar Trial acronym: Northstar overallStatus: RECRUITING date: 2024-01-01 date: 2025-01-01 date: 2025-01-01 date: 2024-04-11 date: 2024-04-11 name: Amsterdam UMC, location VUmc class: OTHER briefSummary: The introduction of real-time MRI-guided cardiac ablation therapy, a significant advancement in interventional medicine, necessitates precise catheter tracking for accurate navigation within the complex cardiac anatomy. The introduction of the NorthStar software as an active tracking system holds promise for improving the precision and efficiency of catheter manipulation during these procedures. However, a rigorous evaluation of its accuracy and reliability in a clinical setting is crucial to validate its viability.
The objective of this study is to evaluate the accuracy of catheter localization using the NorthStar software during real-time MRI-guided cardiac ablation therapy. conditions: Flutter, Atrial studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 20 type: ESTIMATED name: NorthStar measure: Accuracy of Catheter Localization measure: Influences of breathing pattern measure: Influences of procedure duration measure: Influences of complications during ablation measure: Influences of patient characteristics sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Amsterdam UMC status: RECRUITING city: Amsterdam country: Netherlands name: Marco Gotte role: CONTACT lat: 52.37403 lon: 4.88969 hasResults: False
nctId: NCT06359665 id: HSR230544 briefTitle: Oral Curcumin for the Treatment of Pain of Thumb Base Joint (CMC) Arthritis overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-06-01 date: 2025-06-01 date: 2024-04-11 date: 2024-04-11 name: Brent DeGeorge class: OTHER briefSummary: The goal of this clinical trial is to learn about the use of turmeric (Curcumin) as a treatment for pain of thumb-joint arthritis. Turmeric is commonly being used as an over-the-counter treatment for musculoskeletal pain. Clinical trials have demonstrated a pain-relief benefit for knee osteoarthritis, however no clinical trial has been performed to establish efficacy of curcumin in humans for thumb-joint arthritis. The main question\[s\] it aims to answer are:
nctId: NCT06359652 id: IRB24-0421 briefTitle: Get Fit for Function overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2029-04 date: 2029-04 date: 2024-04-11 date: 2024-04-11 name: University of Chicago class: OTHER briefSummary: The purpose of this study will be to implement and evaluate a prehab program for pre-frail and frail adults who need to undergo thoracic surgery. The study team hypothesizes using an implementation framework will increase the reach, effectiveness, adoption, and implementation of the prehab program. conditions: Thoracic conditions: Frailty studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DEVICE_FEASIBILITY masking: NONE count: 100 type: ESTIMATED name: Prehabilitation Program (Apple Watch Series 6 with exercise flipbook) measure: The change of functional status using the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework for implementation evaluation. measure: Number of Participants with Postoperative Complications measure: Number of Participants length of hospital stay post-operative. measure: Number of Participants discharge to not-home post-operative. sex: ALL minimumAge: 50 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The University of Chicago city: Chicago state: Illinois zip: 60637 country: United States name: Viviana Camacho role: CONTACT phone: 773-795-4391 email: vcamacho@bsd.uchicago.edu name: Leila Yazdanbakhsh role: CONTACT phone: 773-834-5087 email: leila.yazdanbakhsh@bsd.uchicago.edu name: Maria Madariaga, MD role: PRINCIPAL_INVESTIGATOR lat: 41.85003 lon: -87.65005 hasResults: False
nctId: NCT06359639 id: USM/JEPeM/KK/23080645 briefTitle: Cognitive Restructuring in Managing Breakup Distress and Promoting Posttraumatic Growth Among Malaysian Young Adults overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-09 date: 2024-09 date: 2024-04-11 date: 2024-04-11 name: Michelle Choong Poh Kin class: OTHER briefSummary: The goal of this clinical trial is to assess the effectiveness of cognitive restructuring in reducing breakup distress and promoting personal growth among Malaysian young adults. Cognitive restructuring is a therapy skill that focuses on changing unhelpful thoughts. The main question it aims to answer is: Are there differences in their breakup distress and personal growth after receiving cognitive restructuring compared to counselling? Participants will receive five online sessions of either cognitive restructuring or counselling. Data on participants' breakup distress and personal growth will be collected before and after completion of sessions. The hypothesis is that cognitive restructuring will reduce breakup distress and increase personal growth more than counselling. conditions: Breakup Distress conditions: Posttraumatic Growth studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 80 type: ESTIMATED name: Cognitive restructuring name: Supportive counselling measure: Breakup distress measure: Posttraumatic growth sex: ALL minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT hasResults: False
nctId: NCT06359626 id: YHP2205 briefTitle: Bioequivalence Study Between YHP2205 and YHR2401 in Healthy Volunteers overallStatus: NOT_YET_RECRUITING date: 2024-07-09 date: 2024-07-19 date: 2024-07-24 date: 2024-04-11 date: 2024-04-11 name: Yuhan Corporation class: INDUSTRY briefSummary: A randomized, open-label, single-dose, 2-sequence, 2-period, crossover clinical trial to investigate the bioequivalence between YHP2205 and YHR2401 in healthy volunteers conditions: Healthy Volunteers studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: two-way crossover primaryPurpose: TREATMENT masking: NONE count: 60 type: ESTIMATED name: YHP2205 name: YHR2401 measure: Area under the plasma drug concentration-time curve [AUCt] measure: Maximum plasma concentration [Cmax] measure: Area under the plasma drug concentration-time curve from time 0 to infinity [AUCinf] measure: Area under the plasma drug concentration-time curve/Area under the plasma drug concentration-time curve from time 0 to infinity [AUCt/AUCinf] measure: Time of peak concentration [Tmax] measure: Terminal phase of half-life [t1/2] sex: ALL minimumAge: 19 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06359613 id: 029/IRC/BMR briefTitle: Efficacy Assessment of Gluten Free Cupcakes overallStatus: COMPLETED date: 2019-10-03 date: 2019-12-15 date: 2020-01-03 date: 2024-04-11 date: 2024-04-22 name: University of Veterinary and Animal Sciences, Lahore - Pakistan class: OTHER briefSummary: Randomized controlled trial will be conducted after getting informed consent form from each study participant meeting inclusion criteria (n=70, 35 control group +35 intervention group, 3-8years of age). After consumer acceptance against various attributes of aglutenic cupcake, the product will be provided in polyethylene bags containing 28 cupcakes (35gm by weight/cupcake, 2 cupcakes for each day) providing approximately 20% daily value (DV) of energy. Cupcakes of equal weight and size made with rice flour (mostly used recipe) will be provided to the control group. Further product will be provided on follow-up visits. The compliance to a gluten free diet GFD and supplemented product will be confirmed by a Food Frequency Questionnaire (FFQ). conditions: Celiac Disease in Children studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The product will be provided to intervention group (n=50) in polyethylene bags containing 28 cupcakes (35gm by weight/cupcake, 2/day) providing approximately 20%DV of energy. Cupcakes of equal weight and size made with rice flour (mostly used recipe) will be provided to the control group (n=50) primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 75 type: ACTUAL name: nutrient rich food product name: food product measure: Body Weight measure: Height of the patients measure: Mid upper Arm Circumference (MUAC) measure: Body Mass Index (BMI) measure: Complete Blood Count (CBC) measure: Total Protein measure: Lipid Profile measure: Liver Enzymes measure: Serum Electrolytes measure: Gastrointestinal Symptoms sex: ALL minimumAge: 3 Years maximumAge: 8 Years stdAges: CHILD facility: UVAS city: Lahore state: Punjab zip: 54000 country: Pakistan lat: 31.558 lon: 74.35071 hasResults: False
nctId: NCT06359600 id: HS-10501-101 briefTitle: A Study of HS-10501 Tablets in Healthy Subjects overallStatus: RECRUITING date: 2024-03-14 date: 2025-01-31 date: 2025-06-30 date: 2024-04-11 date: 2024-04-11 name: Jiangsu Hansoh Pharmaceutical Co., Ltd. class: INDUSTRY briefSummary: The purpose of this study is to evaluate the safety, tolerability, Pharmacokinetics and Pharmacodynamics of single dose and multiple dose of HS-10501 tables in healthy subjects. This is the first clinical study of HS-10501 tables. This study has 2 parts. Parts A involve a single dose of HS-10501 tables or placebo and will last about 8 days. Also, this part will also further explore the food effect. Parts B involve multiple doses of HS-10501 tables or placebo and will last about 4 weeks. conditions: Healthy Subjects studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 84 type: ESTIMATED name: HS-10501 tablet name: Placebo measure: Incidence and severity of adverse events(AE) , serious AEs and AE leading to withdrawal from treatment. measure: Number of participants with clinically significant abnormalities in lab tests measure: Number of participants with clinically significant change from baseline in vital signs measure: Change from baseline in Electrocardiogram (ECG) measure: Pharmacokinetic (PK) profile of HS-10501 - AUC0-t measure: Pharmacokinetic (PK) profile of HS-10501 - AUC0-∞ measure: Pharmacokinetic (PK) profile of HS-10501 - Cmax measure: Pharmacokinetic (PK) profile of HS-10501 - Tmax measure: Pharmacokinetic (PK) profile of HS-10501 - t1/2 measure: Pharmacokinetic (PK) profile of HS-10501 - CL/F measure: Pharmacokinetic (PK) profile of HS-10501- Vz/F measure: Pharmacokinetic (PK) profile of HS-10501-λz measure: Pharmacokinetic (PK) profile of HS-10501- AUC0-τ measure: Pharmacodynamic (PD) profile of doses of HS-10501 - AUC0-t of blood glucose-time curve after oral glucose tolerance test (OGTT) measure: Pharmacodynamic (PD) profile of doses of HS-10501 - AUC0-t of blood insulin-time curve after oral glucose tolerance test (OGTT) measure: body weight changes sex: ALL minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: The second hospital of Anhui University status: RECRUITING city: Hefei state: Anhui zip: 230601 country: China name: Wei Hu, MD role: CONTACT phone: 13856086475 email: ayefygcp@163.com lat: 31.86389 lon: 117.28083 hasResults: False
nctId: NCT06359587 id: H22-03005 briefTitle: Re-Purposing the Ordering of Routine Laboratory Tests in Hospitals in British Columbia acronym: RePORT-BC overallStatus: NOT_YET_RECRUITING date: 2024-05-06 date: 2026-10-01 date: 2026-10-01 date: 2024-04-11 date: 2024-04-15 name: University of British Columbia class: OTHER name: Providence Health & Services name: Vancouver Coastal Health name: Fraser Health name: Interior Health name: Northern Hospital, Australia name: Canadian Institutes of Health Research (CIHR) name: Island Health briefSummary: The goal of this stepped-wedge cluster randomized trial is to assess the impact of a laboratory test overuse intervention bundle on laboratory test utilization in 6 health authorities (16 hospitals) in British Columbia. The main question it aims to answer is if the intervention bundle, inclusive of healthcare provider and patient engagement tools, can be effectively implemented for hospitalized medical inpatients in 16 hospitals across BC and reduce laboratory test over-use. Researchers will compare hospital clusters that receive the intervention at different (sequential) time points to see if there are significant changes in the measured outcomes after the intervention. conditions: Hospital Acquired Condition studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: Intervention Arm (Intervention Bundle Implementation):
This arm represents the time periods when the hospital units do not receive the intervention bundle. This time period is the control period. Each hospital will contribute to intervention and control period data. primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 700000 type: ESTIMATED name: Laboratory test overuse (LTO) Bundle measure: Change in number of target laboratory tests ordered per patient-day with LTO bundle compared to control period without LTO bundle measure: Change in number of total laboratory tests ordered per patient-day with the LTO bundle measure: Rate of hospital re-admissions and mortality sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06359574 id: IRB-24-0209 briefTitle: Core Competency Model for Corrections acronym: CCM-C overallStatus: ENROLLING_BY_INVITATION date: 2024-04-05 date: 2024-12-31 date: 2025-01-30 date: 2024-04-11 date: 2024-04-16 name: University of North Carolina, Charlotte class: OTHER name: North Carolina Department of Adult Corrections name: North Carolina Department of Health and Human Services briefSummary: The overall goal of this project is to design, implement, and revise the Core Competency Model for Corrections (CCM-C), an evidence-based Self-Directed Violence (SDV) prevention training program for correctional mental health providers in the North Carolina Department of Adult Corrections (DAC). The proposed specific aims are: