hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06339502 id: Duzce-U-merve0002 briefTitle: The Effect of the Use of Jigsaw Technique on Nursing Students' Critical Article Reviews and Students' Opinions overallStatus: NOT_YET_RECRUITING date: 2024-03-22 date: 2024-04-22 date: 2024-05-24 date: 2024-04-01 date: 2024-04-01 name: Duzce University class: OTHER briefSummary: Studies have proven that the Jigsaw learning method, one of the innovative learning methods, is an effective educational learning tool for nursing students. For nursing education to be sufficient to provide students with the modern roles required by the profession, students must actively learn instead of a memorized undergraduate education. -Training programs should enable them to participate in the teaching process. One of these programs is cooperative learning methods. The jigsaw learning technique creates a contemporary learning model by creating a positive learning environment, individualizing students and developing a sense of responsibility. No scientific literature has been found regarding the effect of the Jigsaw learning method on teaching critical article reading skills in nursing research courses in nursing education. It is assumed that the data obtained in this study will contribute to the effect of critical article reading training given using the Jigsaw technique, one of the cooperative learning techniques in nursing education, on students' critical article reviews and opinions about the technique. conditions: Education, Distance conditions: Students, Nursing studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 144 type: ESTIMATED name: Jigsaw Technique measure: Critical Thinking Disposition Scale measure: The Kolb Learning Style Inventory-III measure: Self Directed Learning Skills Scale sex: ALL minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: Duzce University city: Duzce zip: 81100 country: Turkey name: Atiye Erbaş, PhD role: CONTACT email: atiyeerbas@duzce.edu.tr lat: 40.83889 lon: 31.16389 facility: Düzce University city: Duzce zip: 81100 country: Turkey lat: 40.83889 lon: 31.16389 hasResults: False
nctId: NCT06339489 id: 2022DZMEC-PG-34 briefTitle: The Bone Metabolism Characteristics of Premature Ovarian Insufficiency acronym: POI overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-12-01 date: 2025-02-01 date: 2024-04-01 date: 2024-04-02 name: Shi Yun class: OTHER briefSummary: Explore the bone metabolism characteristics of premature ovarian insufficiency. conditions: Premature Ovarian Insufficiency conditions: Bone Diseases, Metabolic conditions: Bone Mineral Density studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 60 type: ESTIMATED name: Testing the serum levels of bone metabolic markers measure: tartrate resistant acid phosphatase-5b, TRACP-5b measure: bone specific alkaline phosphatase, BALP measure: bone mineral density, BMD sex: FEMALE minimumAge: 18 Years maximumAge: 39 Years stdAges: ADULT facility: Dongzhimen Hospital, Beijing University of Chinese Medicine city: Beijing country: China lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06339476 id: Dilara ÜLGER ÖZBEK briefTitle: Exploring the Complex Links Between Menstrual Irregularity and Cellular Markers overallStatus: COMPLETED date: 2023-06-01 date: 2024-03-10 date: 2024-03-24 date: 2024-04-01 date: 2024-04-03 name: Cumhuriyet University class: OTHER briefSummary: A cross-sectional study design was employed, involving 56 premenopausal participants with ages ranging from 20 to 49 years. Serum samples were collected during the early follicular phase, and levels of some biochemicals parameters analyzed. conditions: Menstrual Irregularity conditions: Menstrual Cycle Abnormal studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: In the overall study population of 56 subjects recruited from, Sivas Cumhuriyet University Faculty of Medicine Research and Practice Hospital, Gynecology and Obstetrics Clinic, divided into two groups: irregular menstrual cycle (n=28) and regular menstrual cycle control group (n=28). While those who met the criteria for menstrual irregularity were included, those with another gynecological disease (PCOS, endometriosis, etc.) and additional diseases (diabetes, insulin resistance, cancer, heart disease, etc.) were excluded from the study. All participants provided written informed consent before participating in the study. Participants were asked to report the average length of their menstrual cycle over the past six months, as well as the consistency of cycle length. Menstrual regularity was assessed by self-report using a standardized questionnaire. primaryPurpose: HEALTH_SERVICES_RESEARCH masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 56 type: ACTUAL name: Serum ADMA, MDA and M30 levels mesurment measure: ADMA, M30 and MDA levels mesurment in the blood serum to compare between patient and control. sex: FEMALE minimumAge: 20 Years maximumAge: 49 Years stdAges: ADULT facility: Sivas Cumhuriyet University Hospital city: Sivas state: Centre zip: 58050 country: Turkey lat: 39.74833 lon: 37.01611 hasResults: False
nctId: NCT06339463 id: AAAU7985 briefTitle: Self-Distancing for Pediatric Anxiety and OCD overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-05 date: 2024-04-01 date: 2024-04-01 name: Columbia University class: OTHER briefSummary: Self-Distancing is a cognitive technique that involves shifting perspective away from first person to promote an adaptive, self-reflective stance in emotionally charged situations. This trial aims to help learn how self-distancing may increase approach during exposure and thereby improve treatment response. To find out if self-distancing works by helping children approach fear inducing stimuli, the study will look at behaviors related to approach as well as symptom severity, before, after and during treatment.
The study hypothesizes that Self-Distancing will produce greater increases in approach behaviors and greater decreases in anxiety severity than in the Classic Exposure. conditions: Anxiety Disorders conditions: Obsessive-Compulsive Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Youth will be randomized 10 weekly exposure therapy sessions with or without self-distancing. These conditions will run in parallel. primaryPurpose: TREATMENT masking: SINGLE maskingDescription: The rater will be blinded to which condition, self-distancing or classic exposure, child participants receive. whoMasked: OUTCOMES_ASSESSOR count: 35 type: ESTIMATED name: Self-Distancing (EXSD) name: Classic Exposure (EXC) measure: Treatment Engagement and Adherence Ratings (TEARS) measure: Anxiety Disorders Interview Schedule for DSM-5 (ADIS) Clinical Severity Rating (CSR) measure: Child Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) measure: Screen for Child Anxiety Related Disorders (SCARED)- Parent and Child measure: Obsessive-Compulsive Inventory - Child Version (OCI- CV) measure: Toronto Obsessive Compulsive Scale, Parent version (TOCS) measure: Clinical Global Impression of Severity (CGI-S) Scale measure: Clinical Global Impression of Improvement (CGI-I) Scale sex: ALL minimumAge: 7 Years maximumAge: 17 Years stdAges: CHILD facility: Columbia University Irving Medical Center city: New York state: New York zip: 10019 country: United States name: Sherry Chen role: CONTACT phone: 734-276-0443 email: yc4415@cumc.columbia.edu name: Rebecca Grossman, Ph.D. role: CONTACT phone: 734-276-0443 email: rg3347@cumc.columbia.edu name: Kate Fitzgerald, MD role: PRINCIPAL_INVESTIGATOR lat: 40.71427 lon: -74.00597 hasResults: False
nctId: NCT06339437 id: Adeel3 briefTitle: Enhanced Recovery After Cholecystectomy overallStatus: COMPLETED date: 2023-04-01 date: 2023-10-30 date: 2023-11-01 date: 2024-04-01 date: 2024-04-12 name: Children Hospital and Institute of Child Health, Lahore class: OTHER briefSummary: this study will be conducted involving patients of all genders between the ages of 20 and 60 years who will undergo elective laparoscopic cholecystectomy for uncomplicated symptomatic gallstone disease. The study will be conducted in Department of West Surgical Ward, Mayo Hospital, Lahore, after receiving approval from the hospital's Ethical Committee. Patients having other co-morbid conditions, pregnant patients, and those undergoing laparoscopic cholecystectomy converted to open surgery will be excluded from the study. LFTs and other baseline investigations will be done routinely of every patient. Written informed consent will be obtained from all the patient. Patients will be divided into two groups with 30 patients in each group. Group A will consist of patient in whom ERAS protocol will be implemented and Group B in whom ERAS protocol will not be implemented. conditions: Cholelithiases studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: ERAS protocols applied primaryPurpose: SUPPORTIVE_CARE masking: SINGLE maskingDescription: outcomeassessor was not told about group allocation whoMasked: OUTCOMES_ASSESSOR count: 60 type: ACTUAL name: ERAS Protocol measure: PONV measure: Visual Analogue Scale score sex: ALL minimumAge: 20 Years maximumAge: 60 Years stdAges: ADULT facility: The Children Hospital city: Lahore state: Punjab zip: 42000 country: Pakistan lat: 31.558 lon: 74.35071 hasResults: False
nctId: NCT06339424 id: 202400156A3 briefTitle: Atezolizumab and Bevacizumab With Photon Radiotherapy for Unresectable Hepatocellular Carcinoma acronym: PhotonAB overallStatus: NOT_YET_RECRUITING date: 2024-03-29 date: 2029-03-30 date: 2031-03-30 date: 2024-04-01 date: 2024-04-01 name: Chang Gung Memorial Hospital class: OTHER briefSummary: Atezolizumab (anti-programmed death-ligand 1; anti-PD-L1) in conjunction with bevacizumab (anti-vascular endothelial growth factor; anti-VEGF) has become the established standard first-line systemic treatment for unresectable hepatocellular carcinoma (HCC). Despite an improved objective response rate (ORR) of 27%, the majority of patients face HCC progression and liver failure \[Finn et al., N Engl J Med 2020\]. Developing a new combined treatment strategy to overcome resistance to anti-PD-L1 and anti-VEGF is essential to improve patient outcomes.
Radiation treatment (RT) is highly efficacious in controlling localized solid tumors and has become an integral component of the treatment algorithm for unresectable HCC. Importantly, a recent retrospective cohort described that RT combined with atezolizumab plus bevacizumab was associated with favorable median overall survival of 16.1 months (Manzar et al, Cancers 2022). Our preclinical study (Hsieh et al., Science Immunology 2022) revealed that RT combined with PD-L1/PD-1 blockade induces immunogenic cell death and tumor antigen cross-presentation in antigen-presenting cells, thereby potentiating the systemic antitumor T cell responses in murine tumor models. However, whether the combinatorial therapy with RT, atezolizumab, and bevacizumab can trigger synergistic antitumor effects and systemic immune mobilization has not yet been validated in clinical trials for unresectable HCC.
Both atezolizumab/bevacizumab and X-ray RT are approved treatment methods for unresectable HCC by the U.S. and Taiwan Food and Drug Administration (FDA). The present phase II non-randomized trial aims to prospectively document the therapeutic efficacy, safety, and immunological responses in patients with unresectable HCC treated with atezolizumab/bevacizumab combined with conventional photon radiotherapy. conditions: Hepatocellular Carcinoma studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 45 type: ESTIMATED name: Atezolizumab name: Bevacizumab name: Photon radiotherapy measure: Progression free survival (PFS) measure: Local control (LC) measure: Time to progression (TTP) measure: Overall Response Rate (ORR) measure: Overall survival (OS) measure: Incidence and severity of adverse events sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Chang Gung Memorial Hospital at Linkou city: Taoyuan City zip: 333 country: Taiwan lat: 24.95233 lon: 121.20193 hasResults: False
nctId: NCT06339411 id: 202302239A3 briefTitle: Exploring Cerebrolysin in Late Thrombectomy for Stroke: Blood-brain Barrier Biomarkers and Imaging Insights overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-12-31 date: 2027-07-31 date: 2024-04-01 date: 2024-04-02 name: Chang Gung Memorial Hospital class: OTHER briefSummary: Background:
Stroke is a leading cause of mortality and disability globally, with acute ischemic strokes(AIS) due to Large Vessel Occlusion (LVO) presenting significant treatment challenges. Mechanical thrombectomy (MT) has emerged as an effective intervention for AIS within an 8-hour window from symptom onset. However, the potential to extend this window up to 24 hours for select patients could revolutionize outcomes for those arriving late at comprehensive stroke centers. This study investigates the efficacy and safety of Cerebrolysin as an adjunct therapy to MT in extended time window and improving patient recovery.
We conducted a multi-center, prospective, randomized study within the Chang Gung Memorial Hospital system in Taiwan, targeting 100 AIS patients eligible for MT beyond the traditional 8-hour window. Participants were randomized to receive either standard care or Cerebrolysin post-MT, initiated within 24 hours of stroke onset and continued for 14 days. The study assessed neurological, neuropsychological, and biomarker outcomes at multiple time points post-stroke to evaluate the effects of Cerebrolysin on recovery.
The primary outcome will measure the proportion of patients achieving favorable functional outcomes (modified Rankin Scale 0-2) at 90 days. Secondary outcomes include the impact of Cerebrolysin on secondary hemorrhagic transformation, brain edema, mortality rates, and quality of life. The study aims to provide comprehensive data on the benefits of adding Cerebrolysin to the standard post-MT care, focusing on its potential to protect against reperfusion injuries and maintain blood-brain barrier integrity.
By evaluating the role of Cerebrolysin in conjunction with MT, this study aims to extend the therapeutic window for AIS treatment, offering hope for improved outcomes for patients who would otherwise be ineligible for current reperfusion therapies. The findings may pave the way for new guidelines in stroke management, emphasizing the importance of integrated care approaches in enhancing patient recovery. conditions: Acute Ischemic Stroke studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 100 type: ESTIMATED name: Cerebrolysin measure: Functional Recovery and Complication Rates Post-Thrombectomy measure: Imaging and High cortical Functional Assessment Endpoints sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06339398 id: 002-2023 briefTitle: To Evaluate the Dose-response Effects of a Defined Volume of Physical Exercise on the Change of Peripheral Biomarkers, Clinical Response and Brain Connectivity in Parkinson's Disease: a Prospective, Observational, Cohort Pilot Study acronym: METEX-PD overallStatus: ENROLLING_BY_INVITATION date: 2024-05 date: 2025-12-31 date: 2028-05-31 date: 2024-04-01 date: 2024-04-01 name: Casa di Cura San Raffaele Cassino class: NETWORK name: IRCCS San Raffaele Roma name: San Raffaele Telematic University name: University of Rome Tor Vergata name: University of Urbino "Carlo Bo" briefSummary: This is a prospective, observational, cohort pilot study of standardize volume of aerobic exercise on changes in BDNF concentration at 4-weeks of exercise training among Parkinson disease patients.
nctId: NCT06339385 id: KY 2020-153-02 briefTitle: Management of PADIS in Emergency Intensive Care Unit overallStatus: COMPLETED date: 2021-06-13 date: 2021-08-12 date: 2021-08-12 date: 2024-04-01 date: 2024-04-02 name: Capital Medical University class: OTHER name: Beijing Tiantan Hospital name: The First Affiliated Hospital of Anhui Medical University name: The First Affiliated Hospital of Dalian Medical University name: Fudan University name: Affiliated hospital of Guilin medical university,China name: The Second Affiliated Hospital of Hainan Medical University name: The First Hospital of Hebei Medical University name: The First Hospital of Jilin University name: Southwest Hospital, China name: General hospital of shenyang military command name: Beijing Anzhen Hospital name: Mianyang Central Hospital name: Tianjin Medical University General Hospital name: The First Affiliated Hospital of Zhengzhou University name: The Jiangxi Provincial People's Hospital briefSummary: Investigate the prevalence of PADIS in EICU, as well as the awareness and clinical implementation status of medical staff towards PADIS.
The investigators conducted a multicenter cross-sectional survey in mainland China, including a one-day point prevalence investigation and a questionnaire survey. The inclusion criteria encompassed all adult patients admitted to the participating emergency department intensive care units (EDICUs) during the on-site screening, while exclusion criteria comprised patients aged less than 18 years, EDICU stays duration less than 24 hours before the screening, and participation in other concurrent trials. Hospital and nursing records from the 24 hours preceding enrollment were examined to document the assessment rate of pain, agitation-sedation, and delirium. Physicians and nurses on duty 24 hours before the patients\' enrollment was invited to complete the questionnaire survey regarding the ICU profiles, professional expertise, assessment and treatment of PAD, early mobilization, and sleep improvement practices. conditions: Pain conditions: Agitation, Emergence conditions: Delirium conditions: Critical Illness studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 162 type: ACTUAL name: PADIS assessment measure: PADIS assessment rate measure: Rates of analgesic and sedative administration measure: Rate of accidental removal of the catheter during the EICU stay measure: EDICU length of stay measure: The hospital length of stay sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Beijing Tiantan hospital city: Beijing state: Beijing zip: 100070 country: China lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06339372 id: AP1912-30102 briefTitle: Perioperative Supplementation With Immunonutrition and Its Impact on Surgical Outcome and Pain in Oral Cavity or Mandibular Tumours overallStatus: COMPLETED date: 2023-02-01 date: 2023-08-01 date: 2023-08-01 date: 2024-04-01 date: 2024-04-02 name: Cairo University class: OTHER briefSummary: The aim of this study was to investigate the effect of adding omega 3 and dipeptiven to standard feeding in head and neck patients who will undergo oral cavity tumour resection or mandibular tumour resection (immunonutrrition mixture) on wound infection, fistula formation and length of hospital stay ,total dose of intraoperative and postoperative opioids (opioid consumption and pain incidence ,mortality and other postoperative complications as urinary tract infection (UTI) and pneumonia. conditions: Immunonutrition conditions: Surgical Outcome conditions: Pain conditions: Oral Cavity conditions: Mandibular Tumor studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 176 type: ACTUAL name: Standard feeding name: Omega 3 and dipeptiven measure: The incidence of wound infection measure: Fistula formation measure: Length of hospital stay measure: Total dose of intraoperative opioids measure: Total dose of postoperative opioids measure: Degree of pain measure: The incidence of mortality measure: The incidence of complications sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Cairo University city: Cairo zip: 11796 country: Egypt lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06339359 id: 2024-02-014 briefTitle: A Pilot Study to Develop a Behavior-based Screening Protocol for Early Diagnosis of Autism Spectrum Disorders overallStatus: RECRUITING date: 2024-03-01 date: 2025-03-31 date: 2025-03-31 date: 2024-04-01 date: 2024-04-01 name: Bundang CHA Hospital class: OTHER briefSummary: This study aims to collect basic data to develop a tool for early screening of autism spectrum disorder (ASD) in children and adolescents through eye tracking and motion analysis. conditions: ASD studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 200 type: ESTIMATED name: Exmainations including clinical measurement, kinetic and kinematic measurmetns. Behavioral assessments measure: K-BSID-Ⅲ measure: ADI-R measure: M-CHAT measure: ADOS-2 measure: K-WPPSI-Ⅳ measure: K-CARS-2 measure: CBCL measure: SCQ measure: GMFM measure: HFT measure: BOT-2 measure: VMI-6 measure: SP measure: Eye Tracking measure: Motion Analysis sex: ALL maximumAge: 19 Years stdAges: CHILD stdAges: ADULT facility: CHA Bundang Medical Center, CHA University status: RECRUITING city: Seongnam-si state: Gyeonggi-do zip: 463-712 country: Korea, Republic of name: Minyoung Kim, M.D., Ph.D. role: CONTACT phone: 82-31-780-1872 email: kmin@cha.ac.kr lat: 37.43861 lon: 127.13778 hasResults: False
nctId: NCT06339346 id: 29BRC24.0028 - PROMOT1 briefTitle: Analysis of Histopathological Factors Predictive of Lymph Node Involvement and Management Practices in pT1 Colorectal Cancers Treated by Primary Endoscopic Resection: a Retrospective Population-based Study (PROMOT1) acronym: PROMOT1 overallStatus: ACTIVE_NOT_RECRUITING date: 2022-12-01 date: 2024-04-30 date: 2024-04-30 date: 2024-04-01 date: 2024-04-01 name: University Hospital, Brest class: OTHER briefSummary: Colorectal cancers (CRC) extending beyond the muscularis mucosae and invading the submucosa without extending beyond it are classified as pT1.
The aim of this study is therefore to analyze the current histopathological criteria predictive of lymph node invasion, in order to more accurately select candidates for surgical management. conditions: Colorectal Cancer conditions: Colorectal Adenocarcinoma studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: RETROSPECTIVE count: 400 type: ESTIMATED measure: Analysis of lymph node invasion rates as a function of tumor characteristics measure: Population demographics measure: lesion characteristics measure: management measure: recurrence measure: survival sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Chu Brest city: Brest zip: 29609 country: France lat: 48.3903 lon: -4.48628 hasResults: False
nctId: NCT06339333 id: RRECB0523EC briefTitle: Evaluation of ACT Now GAIN Later overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-03-01 date: 2025-04-01 date: 2024-04-01 date: 2024-04-01 name: University College Dublin class: OTHER briefSummary: The goal of this Randomised Control Trial is to evaluate a Psychologist Guided Self Help Video Parenting Programme based on principles of Acceptance and Commitment Therapy (ACT)