hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06340542 id: UDhaka briefTitle: Comparison of Thoracic Mobility Exercise Versus Manual Release Technique in Minimizing Upper Back Pain overallStatus: COMPLETED date: 2023-11-01 date: 2023-12-31 date: 2024-01-31 date: 2024-04-01 date: 2024-04-02 name: University of Dhaka class: OTHER briefSummary: Methodology: study aims to evaluate the effectiveness of thoracic mobility exercise and manual release technique in terms of pain intensity, thoracic mobility, muscle strength and improving disability.
Study Design: Study was conducted in Service unit of Department of Physiotherapy at university of peradeniya. Undergraduates who are currently having upper back pain for more than seven days was selected as sample. It is a randomized Controlled trail, Double blinded study. Participants allowed randomly to both groups which are experimental group which will receive thoracic mobility exercises and control group which will receive myofascial release and joint mobilization treatment. Total sample size was 60. conditions: Upper Back Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: This study is a Randomized Control Trial, Double- Blinded study. Participants and accessors was blinded. Participants were allocated randomly in to two groups which are experimental group which will receive thoracic mobility exercises and control group which will receive myofascial release and joint mobilization treatment by using lottery method. primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Participants' allocation was concealed by using lottery method whether there are in exercise group or manual therapy group. Accessors was blinded which means they were not aware about the treatment or therapy which was obtained by the participants whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 57 type: ACTUAL name: Thoracic Mobility exercises name: Manual Release technique measure: Pain Intensity measure: Range of Motion measure: Muscle strength measure: Disability level - self perception sex: ALL minimumAge: 20 Years maximumAge: 26 Years stdAges: ADULT facility: Vithursha Sivakumar city: Jaffna state: Northern zip: 40001 country: Sri Lanka lat: 9.66845 lon: 80.00742 typeAbbrev: Prot_SAP_ICF hasProtocol: True hasSap: True hasIcf: True label: Study Protocol, Statistical Analysis Plan, and Informed Consent Form date: 2023-10-09 uploadDate: 2024-03-25T22:35 filename: Prot_SAP_ICF_000.pdf size: 1324441 hasResults: False
nctId: NCT06340529 id: CLS_SIMULATION briefTitle: Comparison of the Perception of Non-technical Skills overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2024-05-31 date: 2024-06-30 date: 2024-04-01 date: 2024-04-03 name: University of Valencia class: OTHER briefSummary: Clinical simulation has recently acquired great importance in the health sciences. It is a pedagogical methodology that is increasingly used in health science degrees, since it is very useful for the acquisition of both technical and non-technical skills (leadership, teamwork and effective communication, among others).
Clinical simulation allows students to achieve these competencies without the need to practice on real patients. For all these reasons, and because of the situation of need generated in recent years, in which internships in hospitals and clinical centers were completely suppressed, the need for our research is justified. conditions: Healthy studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: SCREENING masking: NONE count: 100 type: ESTIMATED name: Clinical Simulation measure: Ottawa Scale sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06340516 id: HER2BNP briefTitle: NT-proBNP to Assess Trastuzumab-induced Cardiotoxicity overallStatus: RECRUITING date: 2024-03-14 date: 2029-03-14 date: 2029-03-14 date: 2024-04-01 date: 2024-04-01 name: Vastra Gotaland Region class: OTHER_GOV briefSummary: Trastuzumab-induced cardiotoxicity (TIC) will be monitored in patients with HER2+ breast cancer undergoing trastuzumab treatment before and after breast cancer surgery. At baseline before start of trastuzumab treatment, echocardiography (ECHO)/multigated Acquisition Scan (MUGA) and measurement of plasma NT-proBNP will be performed. NT-proBNP will be measured again at 6 months and at 12 months of trastuzumab treatment. If elevations in NT-proBNP at 6 months and 12 months occur patients will be referred for ECHO/MUGA. The aim is to assess the sensitivity and specificity to detect TIC with NT-proBNP and whether ECHO/MUGA can be safely replaced by assessment of plasma NT-proBNP levels. conditions: Cardiotoxicity conditions: Breast Cancer conditions: Treatment Side Effects studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: This is a national multicentre phase II trial investigating the sensitivity and specificity of NT-proBNP for the diagnose of cardiac toxicity during primary anti-HER2 blockade. NT-proBNP is compared with the todays´ standard (ECHO/MUGA). primaryPurpose: DIAGNOSTIC masking: NONE count: 700 type: ESTIMATED name: Plasma NT-proBNP measure: Sensitivity and specificity of NT-proBNP to detect trastuzumab-induced cardiotoxicity measure: Prevalence of trastuzumab-induced cardiotoxicity measure: Anthracycline-induced change in NT-proBNP sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Jubileumskliniken, Sahlgrenska University Hospital status: RECRUITING city: Gothenburg zip: 432 45 country: Sweden name: Daniel Giglio, Assoc Prof role: CONTACT phone: +46(0)31-342 16 06 email: daniel.giglio@pharm.gu.se lat: 57.70716 lon: 11.96679 hasResults: False
nctId: NCT06340503 id: IRB00111331 id: WFBCCC 01123 type: OTHER domain: Atrium Health Wake Forest Baptist Comprehensive Cancer Center id: P30CA012197 type: NIH link: https://reporter.nih.gov/quickSearch/P30CA012197 briefTitle: Evaluating a Physical Activity Index for Assessment and Counseling for Breast and Colon Cancer Survivors overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2025-07 date: 2025-08 date: 2024-04-01 date: 2024-04-01 name: Wake Forest University Health Sciences class: OTHER name: National Cancer Institute (NCI) briefSummary: The purpose of this research study is to determine whether using the physical activity index screener, exercise coaching, and self-monitoring will increase physical activity and reduce time spent sitting or being inactive in patients who had breast or colon cancer. conditions: Breast Cancer conditions: Colon Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 20 type: ESTIMATED name: Research-grade accelerometer name: National Comprehensive Cancer Network (NCCN) Education Materials name: Garmin Vivofit activity tracker name: Exercise Consultation Calls name: Interview name: Physical Activity Index Assessment (Intervention Arm) name: Physical Activity Index Assessment (Control Arm) name: Health Surveys measure: Number of Eligible Participants - Participation Rate measure: Percentage of Participants to Complete Exercise Sessions - Adherence measure: Number of Participants Who Complete Study Questionnaires - Retention sex: ALL minimumAge: 50 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Atrium Health Wake Forest Baptist Comprehensive Cancer Center city: Winston-Salem state: North Carolina zip: 27157 country: United States name: Principal Investigator role: CONTACT name: Shirley Bluethmann, PhD role: PRINCIPAL_INVESTIGATOR lat: 36.09986 lon: -80.24422 hasResults: False
nctId: NCT06340490 id: RJMty19-AID002 briefTitle: A Study of RJMty19 in Refractory Systemic Lupus Erythematosus (SLE) overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2026-12-31 date: 2027-12-31 date: 2024-04-01 date: 2024-04-01 name: Guangdong Ruishun Biotech Co., Ltd class: INDUSTRY name: RenJi Hospital name: Peking University People's Hospital name: Changhai Hospital name: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School briefSummary: This study is an open-label, single-arm, dose escalation and dose expansion study to evaluate the safety, maximum tolerated dose, pharmacokinetic characteristics of allogeneic CD19-CAR-DNT cells (RJMty19) after infusion, and preliminary efficacy in systemic lupus erythematosus (SLE) subjects. conditions: Systemic Lupus Erythematosus studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 24 type: ESTIMATED name: RJMty19 (CD19-CAR-DNT cells) measure: Dose-Limiting Toxicity (DLT) measure: Maximum Tolerated Dose (MTD) measure: Incidence of abnormalities measure: Pharmacokinetics (PK) indicator (Cmax) measure: Pharmacokinetics (PK) indicator (AUC) measure: Pharmacokinetics (PK) indicator (CAR copy numbers) measure: Remission rate of SLE based on DORIS criteria measure: Remission rate of SLE based on LLDAS criteria sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Peking University People's Hospital city: Beijing state: Beijing zip: 100044 country: China name: Zhanguo Li, MD, PHD role: CONTACT phone: +086-13910713924 email: li99@bjmu.edu.cn name: Chun Li, MD, PHD role: CONTACT phone: +086-13811190098 email: 13811190098@163.com lat: 39.9075 lon: 116.39723 facility: Nanjing Drum Tower Hospital city: Nanjing state: Jiangsu zip: 210008 country: China name: Lingyun Sun, MD, PhD role: CONTACT phone: +086-025-83105555 email: lingyunsun2012@163.com lat: 32.06167 lon: 118.77778 facility: Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine city: Shanghai state: Shanghai zip: 200001 country: China name: Shuang Ye, MD, PHD role: CONTACT phone: +086-13817615871 email: ye_shuang2000@163.com name: Qiong Fu, MD, PHD role: CONTACT phone: +086-13585603288 email: fuqiong@renji.com lat: 31.22222 lon: 121.45806 facility: Changhai Hospital city: Shanghai state: Shanghai zip: 200433 country: China name: Dongbao Zhao, MD, PhD role: CONTACT phone: +86-15921061314 email: dongbaozhao@163.com name: Jie Gao, MD, PhD role: CONTACT phone: +086-13585561861 email: gaojif@tom.com lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06340477 id: Mahnoor Arif/ REC -01802 briefTitle: Effect of Thoracic SNAGS on Vitals Among Individuals With Forward Head Posture overallStatus: RECRUITING date: 2024-03-01 date: 2024-06 date: 2024-07 date: 2024-04-01 date: 2024-04-01 name: Riphah International University class: OTHER briefSummary: To determine how vitals (heart rate, blood pressure, respiratory rate, oxygen saturation) and craniovertebral angle will be affected by thoracic SNAGs in individuals with forward head posture. conditions: Neck Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 28 type: ESTIMATED name: Thoracic SNAGs with conventional therapy name: conventional therapy measure: Aneroid sphygmomanometer measure: Pulse oximeter measure: Respiratory rate measure: NPRS (Numeric Pain Rating Scale) measure: Inclinometer measure: Photogrammetric method for craniovertebral angle sex: ALL minimumAge: 30 Years maximumAge: 50 Years stdAges: ADULT facility: Pakistan Railway Hospital status: RECRUITING city: Rawalpindi state: Punjab zip: 46000 country: Pakistan name: Maria Khalid, MSOMPT role: CONTACT phone: 03315369768 email: maria.khalid@riphah.edu.pk name: Mahnoor arif, MSOMPT* role: CONTACT name: mahnoor arif, MSOMPT* role: PRINCIPAL_INVESTIGATOR lat: 33.6007 lon: 73.0679 hasResults: False
nctId: NCT06340464 id: REC.67-018-8-1 briefTitle: Preoperative Nutritional Status Scores to Predict PPC in Elderly With Cardiac Surgery overallStatus: RECRUITING date: 2024-03-21 date: 2025-12-31 date: 2026-11-30 date: 2024-04-01 date: 2024-04-01 name: Prince of Songkla University class: OTHER briefSummary: This prospective study investigate prognostic values and compare the role of nutritional status by using GNRI, MNA, and PNI in predicting post-operative pulmonary complication among elderly patients with cardiac surgery. conditions: Cardiac Surgery conditions: Elderly Patient conditions: Postoperative Pulmonary Complication conditions: Nutrition Scoring System studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 229 type: ESTIMATED name: GNRI, PNI, MNA measure: Postoperative pulmonary complication sex: ALL minimumAge: 60 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University status: RECRUITING city: Hat Yai state: Songkhla zip: 90110 country: Thailand name: Panalee Kittisopaporn role: CONTACT phone: 66832422540 lat: 7.00836 lon: 100.47668 hasResults: False
nctId: NCT06340438 id: N-20240004 3rd subproject briefTitle: Investigate the Relationship Between Catastrophizing and the Perception of Itch Intensity in Healthy Individuals overallStatus: NOT_YET_RECRUITING date: 2024-04-27 date: 2025-12-31 date: 2026-12-31 date: 2024-04-01 date: 2024-04-29 name: Aalborg University class: OTHER briefSummary: This project aims to investigate the relationship between different dimensions of catastrophizing (rumination, magnification, and helplessness) as well as some specific personality traits related to catastrophizing tendencies like anxiety sensitivity and fear sensitivity in the modulation of itch and pain intensities in an experimental setting. conditions: Histamine conditions: Cowhage studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: The participants will randomly receive applications of cowhage and histamine. primaryPurpose: BASIC_SCIENCE masking: SINGLE maskingDescription: Participant will be blinded about application of pruritogens. whoMasked: PARTICIPANT count: 46 type: ESTIMATED name: Histamine name: Cowhage measure: Reinforcement Sensitivity Theory - Personality Questionnaire (RST-PQ). measure: The Pittsburg Sleep Quality Index (PSQI) measure: Depression, Anxiety, Stress Scale (DASS-21) measure: Positive And Negative Affect Schedule (PANAS) measure: Pain Catastrophizing Scale (PCS). measure: Itch Catastrophizing Scale (ICS). measure: Learned Helplessness Scale (LHS) measure: Positive And Negative Affect Schedule (PANAS) measure: Depression, Anxiety, Stress Scale (DASS-21) measure: Positive And Negative Affect Schedule (PANAS) measure: Pain Catastrophizing Scale (PCS). measure: Itch Catastrophizing Scale (ICS). measure: Learned Helplessness Scale (LHS) measure: Positive And Negative Affect Schedule (PANAS) measure: Assessment of itch measure: Assessment of pain sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT hasResults: False
nctId: NCT06340425 id: s68727 briefTitle: The Effect of Selective Dorsal Rhizotomy on a Multidimensional Outcome Set in Children With Spastic Cerebral Palsy: a Retrospective Study overallStatus: COMPLETED date: 2018-06-26 date: 2023-12-31 date: 2023-12-31 date: 2024-04-01 date: 2024-04-01 name: Universitaire Ziekenhuizen KU Leuven class: OTHER briefSummary: Cerebral palsy or CP is the single largest cause of childhood physical disability, with a prevalence of 2-3 per 1000 livebirths. Children with CP experience different primary symptoms, including abnormal increased muscle tone or spasticity. Selective dorsal rhizotomy (SDR) is applied in children with spastic CP as a non-reversible tone reduction procedure. Better understanding of the effects of SDR on a multidimensional outcome set in one CP-cohort and on macroscopic muscle morphology can improve insights and clinical decision making. conditions: Cerebral Palsy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 15 type: ACTUAL measure: Overall changes in spasticity measure: Overall change in muscle volume of the medial gastrocnemius measure: Overall changes in muscle length of the medial gastrocnemius measure: Overall changes in muscle cross-sectional area at 50% of muscle belly length measure: Overall changes in gait measure: Overall change in gross-motor function measure: Overall change of spasticity in the plantar flexors measure: Overall change of selectivity in the plantar flexors measure: Overall change of passive range of motion in the ankle and knee joint measure: Overall change of muscle strength in the plantar flexors measure: Scatter plots of muscle morphology data (same parameters as for the primary endpoints) sex: ALL minimumAge: 5 Years maximumAge: 16 Years stdAges: CHILD facility: UZ Leuven city: Leuven state: Vlaams-Brabant zip: 3000 country: Belgium lat: 50.87959 lon: 4.70093 hasResults: False
nctId: NCT06340412 id: MFGM-FOR-HEALTH briefTitle: Effects of Intact and Disrupted Milk Fat Globule Membrane on Postprandial Metabolic Response to High-fat Dairy in Healthy Individuals overallStatus: RECRUITING date: 2024-03-11 date: 2024-10-01 date: 2024-10-01 date: 2024-04-01 date: 2024-04-01 name: University of Aarhus class: OTHER name: Arla Foods briefSummary: The aim of the study is to investigate the effects of milk fat globule membrane (MFGM) content and intactness on postprandial metabolic response to a high-fat meal in humans.
The investigators hypothesize that MFGM content and intactness alters the postprandial lipid profile and substrate metabolism in healthy individuals after consumption of a high-fat meal. conditions: Postprandial Lipid Metabolism studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: A randomized, double-blinded, controlled, crossover trial primaryPurpose: BASIC_SCIENCE masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 12 type: ESTIMATED name: Sandwich with butter-like dairy product (40g milk fat) with intact MFGM. One sandwich for breakfast and one sandwich for lunch. name: Sandwich with butter-like dairy product (40g milk fat) with disrupted MFGM. One sandwich for breakfast and one sandwich for lunch. name: Sandwich with butter-like dairy product (40g milk fat) without MFGM. One sandwich for breakfast and one sandwich for lunch. measure: Difference in postprandial triglycerides measured as area under the curve (AUC). measure: Difference in concentration of GLP-1 measure: Difference in concentration of Ghrelin measure: Difference in concentration of LEAP2 measure: Difference in concentration of FFA measure: Difference in concentration of Insulin measure: Difference in concentration of glucagon measure: Difference in concentration of cholesterol (total, LDL and HDL) measure: Difference in concentration of GIP measure: Difference in concentration of CCK measure: Difference in concentration concentration of Gastrin measure: Difference in concentration concentration of GDF15 measure: Difference in concentration of LPS-BP (Lipopolysaccharide Binding Protein) measure: Difference in concentration concentration of Cytokines measure: Difference in concentration of apoB48 measure: Difference in concentration of apoB100 measure: Difference in glucose concentration measure: Difference in appetite sensation measure: Difference in gastric emptying rate measure: Ad libitum meal test measure: Metabolic rate measure: Substrate metabolism sex: ALL minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: Steno Diabetes Center Aarhus, Aarhus University Hospital status: RECRUITING city: Aarhus zip: 8200 country: Denmark name: Jens H Voigt, MD role: CONTACT phone: +4526395294 email: Jens.voigt@clin.au.dk name: Esben H Søndergaard, MD, PhD role: CONTACT phone: +4528730943 email: Esben.sondergaard@clin.au.dk lat: 56.15674 lon: 10.21076 hasResults: False
nctId: NCT06340399 id: 202312117RINE briefTitle: BCAA in Patients Undergoing Gastric Cancer Surgery overallStatus: NOT_YET_RECRUITING date: 2024-03-28 date: 2029-12-31 date: 2030-12-31 date: 2024-04-01 date: 2024-04-01 name: National Taiwan University Hospital class: OTHER briefSummary: Older patients undergoing gastric cancer resection, at higher risk due to insufficient preoperative muscle mass, are more susceptible to SRML under surgical stress. This not only affects limb muscles but also impacts swallowing muscles, contributing to increased postoperative complications and mortality rates. Enhanced Recovery After Surgery (ERAS) has emerged as a multidisciplinary approach to facilitate postoperative recovery. This study aims to optimize oral nutrition under the ERAS model to observe its impact on SRML. BCAA is essential for skeletal muscles. However, there is limited research on the oral BCAA, whether before or after surgery, concerning SRML and its associated complications. The study entails an 18-month randomized controlled trial with 200 participants. One hundred individuals will take BCAA daily 5 to 14 days before surgery. After surgery, they can progress to a clear liquid diet around postoperative day five while continuing BCAA until 30 days postoperatively. The other one hundred participants will not receive BCAA. The study aims to investigate whether oral BCAA can reduce SRML, muscle loss, and decrease swallowing muscle strength, with observations on postoperative complications and outcomes within one year. conditions: Perioeprative Muscle Loss studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: patients receiving BCAA primaryPurpose: TREATMENT masking: TRIPLE maskingDescription: this is a open label use study whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 200 type: ESTIMATED name: BCAA name: patient not administered BCAA measure: the occurrence of surgical related muscle loss sex: ALL minimumAge: 20 Years maximumAge: 90 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06340386 id: IEO 1365 briefTitle: Italian Validation of a Tool for Assessing Sexual Function After Breast Cancer, FSFI-BC overallStatus: RECRUITING date: 2020-10-19 date: 2024-12-31 date: 2024-12-31 date: 2024-04-01 date: 2024-04-01 name: European Institute of Oncology class: OTHER briefSummary: This is a validation study of the italian language for the Female Sexual Function Index-Breast Cancer questionnaire.
The validation of the instrument in Italian will allow the identification of possible issues related to sexual health and enable the provision of adequate medical and psychosexual counseling to these patients, both in clinical practice and in research studies. conditions: Breast Cancer studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 600 type: ESTIMATED measure: Validation of the italian translation of Female Sexual Function Index-Breast Cancer questionnaire sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: European Institute of Oncology status: RECRUITING city: Milan country: Italy name: Gabriella Pravettoni role: CONTACT lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06340373 id: NICVD/ 2023/ 32 id: NICVD /Ethical/ 2023/ 32 type: OTHER domain: National Institute of Cardiovascular Diseases(NICVD) briefTitle: Clinical and Angiographic Outcomes of Post-drug-coated Balloon Angioplasty in Native Coronary Lesions overallStatus: RECRUITING date: 2024-01-01 date: 2024-12-31 date: 2025-06-30 date: 2024-04-01 date: 2024-04-03 name: National Institute of Cardiovascular Diseases, Bangladesh class: OTHER briefSummary: The progression of cardiac revascularization techniques, starting with standard balloon angioplasty (POBA) and progressing to the creation of drug-coated balloons (DCB) and drug-eluting stents (DES). The study's justification is presented, with a focus on the significance of comprehending the clinical and angiographic outcomes of DCB angioplasty, especially when considering the Bangladeshi population.