nctId: NCT06341777 id: 25M621 briefTitle: Multisensory Telerehabilitation for Visual Field Defects acronym: MUST overallStatus: COMPLETED date: 2020-01-01 date: 2023-12-31 date: 2023-12-31 date: 2024-04-02 date: 2024-04-02 name: Istituto Auxologico Italiano class: OTHER name: IRCCS Fondazione Stella Maris name: Azienda Ospedaliero, Universitaria Meyer briefSummary: Brain injuries may cause the loss of the ability to see portions of the visual field, the so-called visual field defects (VFDs). VFDs significantly impact the survivors' functional recovery and quality of life, with the majority of patients displaying no spontaneous recovery or being left with residual deficits. Among the available therapies for VFDs, the compensatory scanning training is considered the most promising. Yet, current evidence is insufficient to recommend it in clinical practice, and the scientific community has stressed the need of more high-quality research. The present randomized clinical trial in patients with chronic VFDs caused by brain lesions aims at verifying the feasibility and efficacy of a novel telerehabilitation using a multisensory scanning therapy, by measuring its effects on visual functions and daily activities, and by looking for neural indicators of the therapy-induced improvements. conditions: Visual Field Defect Following Cerebrovascular Accident conditions: Hemianopia conditions: Brain Injuries studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 72 type: ACTUAL name: Audio-visual training (AVT) telerehabilitation measure: Change from baseline in Accuracy on the EF Task measure: Change from baseline in Response Times (RTs) on the EF Task measure: Change from baseline in Accuracy on the Triangle Task measure: Change from baseline in RTs on the Triangle Task measure: Change from baseline in RTs on the Numbers Task measure: Change from baseline in omissions on the Bell Test (only children) measure: Change from baseline in RTs on the Bell Test (only children) measure: Change from baseline in Accuracy on the Small Faces Test (only children) measure: Change from baseline in RTs on the Small Faces Test (only children) measure: Change from baseline in Daily Living Dependent on Vision Questionnaire (total score) measure: Change from baseline in the Reading test (reading time) measure: Change from baseline in the Hamilton Anxiety Scale (total score; only adults) measure: Change from baseline in the Beck's Depression Inventory (BDI; total score; only adults) measure: Change from baseline in the Multidimensional Anxiety Scale for Children (MASC; total score; only children) measure: Change from baseline in the Children Depression Inventory (CDI; total score; only children) measure: Change from baseline in the visual field size (only adults) measure: Change from baseline in the amplitude of Visual Evoked Potentials (VEPs) measure: Change from baseline in the latency of Visual Evoked Potentials (VEPs) measure: Change from baseline in the connectivity of the Inferior Longitudinal Fasciculus measure: Change from baseline in the connectivity of the Superior Longitudinal Fasciculus measure: Change from baseline in the connectivity of the Inferior Fronto Occipital Fasciculus measure: Change from baseline in the connectivity of the Optic Radiations measure: Change from baseline in the connectivity of the Optic Tracts sex: ALL minimumAge: 6 Years maximumAge: 70 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Istituto Auxologico Italiano IRCCS city: Milan state: Lombardia zip: 20122 country: Italy lat: 45.46427 lon: 9.18951 hasResults: False