hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06265844 id: IOE-Biyanai briefTitle: Multifunctional Nutrition Tube in Dysphagia for Nasopharyngeal Carcinoma overallStatus: RECRUITING date: 2024-03-01 date: 2024-09-30 date: 2024-09-30 date: 2024-02-20 date: 2024-03-06 name: Zeng Changhao class: OTHER briefSummary: This is a prospective multicenter study with patients with delayed dysphagia after radiotherapy for NPC. Patients enrolled are randomly divided equally into the observation group and the control group. All patients receive conventional care, and the observation group received IOE while the control group received NGT for enteral nutrition support. Baseline information (demographics, medical history, etc.), nutritional status at admission and after treatment, depression, dysphagia, and quality of life (QOL) after treatment as well as adverse events are compared. conditions: Dysphagia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 80 type: ESTIMATED name: Intermittent Oral-esophageal Tube Feeding name: Nasogastric Tube Feeding name: comprehensive rehabilitation therapy measure: Hemoglobin measure: Serum albumin measure: Body Mass Index measure: Serum prealbumin measure: Depression measure: Functional Oral Intake Scale measure: Penetration-Aspiration Scale measure: Swallowing-Quality of Life questionnaire measure: Feeding amount sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Saint Martin Hospital status: RECRUITING city: Hong Kong country: Hong Kong name: Xi Maheen, Master role: CONTACT lat: 22.27832 lon: 114.17469 hasResults: False
nctId: NCT06265831 id: BU-FHS-NC-03 briefTitle: The Effect of Face Hand Fan Application on Dyspnea acronym: HandfanCOPD overallStatus: ACTIVE_NOT_RECRUITING date: 2023-04-01 date: 2023-11-30 date: 2024-03 date: 2024-02-20 date: 2024-02-20 name: Bartın Unıversity class: OTHER name: The Scientific and Technological Research Council of Turkey briefSummary: Diagnosing and managing dyspnea in patients with COPD is very important. Although pharmacological and non-pharmacological methods are used in the management of dyspnea, it is recommended that pharmacological methods be supported by non-pharmacological methods. Hand fan application, which is one of the non-pharmacological methods used in dyspnea management, provides an increase in self-efficacy in patients in addition to the stimulation of cold air flow to the trigeminal nerve branches, mucosa and skin. Although there are studies reporting that applying cold air to the face with a hand fan is effective in reducing the severity of dyspnea in different patient groups, the number of studies examining the effectiveness of applying cold air to the face with a hand fan in patients with COPD is quite limited. This project was planned to determine the effect of applying cold air to the face with a fan on the severity of dyspnea and quality of life in COPD patients. conditions: COPD studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Parallel group: two groups, an intervention group and a control group, receiving complementary therapy. primaryPurpose: SUPPORTIVE_CARE masking: SINGLE maskingDescription: Hospitalized patients with a diagnosis of COPD will be randomized into two groups. The intervention group will have a hand fan applied to the face and be monitored for a week, and the control group will receive routine care at the clinic. Investigators will evaluate outcome measures. whoMasked: PARTICIPANT count: 61 type: ACTUAL name: Hand-fan application to the face measure: Modified Borg Scale measure: Saint George Respiratory Questionnaire sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Necmiye ÇÖMLEKÇİ city: Bartın zip: 74100 country: Turkey lat: 41.63583 lon: 32.3375 hasResults: False
nctId: NCT06265818 id: 2024-KY-0126 briefTitle: The Effect of Active Breathing Exercises in Stroke Patients With Respiratory Rhythm Disorder acronym: ABE-S overallStatus: RECRUITING date: 2024-03-01 date: 2024-05 date: 2024-05 date: 2024-02-20 date: 2024-03-06 name: Zeng Changhao class: OTHER briefSummary: The goal of this clinical trial is to explore The Effect of Active Breathing Exercises in Stroke Patients With Respiratory Rhythm Disorder. Patients will be randomly divided into an observation group and a control group, all receiving routine rehabilitation treatment. On this basis, the observation group will be given Active Breathing Exercises. Researchers will compare dysphagia of two groups. conditions: Respiratory Rhythm Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 80 type: ESTIMATED name: Rehabilitation training name: Active Breathing Exercises measure: The Penetration-Aspiration Scale measure: The Functional Oral Intake Scale measure: Yale Pharyngeal Residue Severity Rating Scale measure: Fiberoptic Endoscopic Dysphagia Severity Scale measure: Murray Secretion Scale measure: Swallowing Quality of Life sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Center Rehabilitation Hospital status: RECRUITING city: Seoul country: Korea, Republic of name: Wei Liu, Master role: CONTACT lat: 37.566 lon: 126.9784 hasResults: False
nctId: NCT06265805 id: 2024-KY-0125-015 briefTitle: Effect of Different Feeding Modes on Psychological Condition and Experience in Stroke Patients acronym: IOE-Xinli overallStatus: RECRUITING date: 2024-02-28 date: 2024-12-30 date: 2024-12-30 date: 2024-02-20 date: 2024-03-06 name: Zeng Changhao class: OTHER briefSummary: The goal of this clinical trial is to compare the differences on Psychological Condition and Experience in ischemic stroke patients using Intermittent Oro-esophageal Tube and Nasogastric Tube. Patients will be randomly divided into an observation group and a control group, all receiving routine rehabilitation treatment. On this basis, the observation group will use Intermittent Oro esophageal Tube for enteral nutrition support, while the control group will use Nasogastric Tube. Researchers will compare Psychological Condition and Experience of two groups. conditions: Ischemic Stroke studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 80 type: ESTIMATED name: comprehensive rehabilitation therapy name: Intermittent Oro-esophageal Tube Feeding name: Nasogastric Tube Feeding measure: Generalized Anxiety Disorder 7 measure: Patient Health Questionnaire-9 measure: Self-made questionnaire sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hsinchu Rehabilitation Hospital status: RECRUITING city: Xinzhu country: Taiwan name: Haim Liu, Master role: CONTACT lat: 22.46205 lon: 120.47335 hasResults: False
nctId: NCT06265792 id: 2024-KY-0125 briefTitle: Efficacy of Stellate Ganglion Block in Obstructive Sleep Apnea acronym: OSA overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-12-01 date: 2024-12-15 date: 2024-02-20 date: 2024-03-06 name: Zeng Changhao class: OTHER briefSummary: The goal of this clinical trial is to test the efficacy of stellate ganglion block in Obstructive Sleep Apnea. The main question it aims to answer are:
• Can stellate ganglion block improve Obstructive Sleep Apnea? Patients were randomly divided into two groups, all provided with routine therapy. Based on this, the experimental group was given stellate ganglion block. The video fluoroscopic swallowing study was done to test the swallowing function before and after the study. conditions: Obstructive Sleep Apnea studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 80 type: ESTIMATED name: routine rehabilitation treatment name: Stellate ganglion block measure: Epworth Sleepiness Scale measure: Apnea-Hypopnea Index sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Center Rehabilitation Hospital city: Seoul country: Korea, Republic of lat: 37.566 lon: 126.9784 hasResults: False
nctId: NCT06265779 id: 2024-KY-0122 briefTitle: Transcranial Direct Current Stimulation Combined With Intermittent Oral to Esophageal Tube on Dysphagia acronym: IOE+JLCJ-S overallStatus: RECRUITING date: 2024-02-29 date: 2024-11-30 date: 2024-12-15 date: 2024-02-20 date: 2024-03-06 name: Zeng Changhao class: OTHER briefSummary: The study is a double-blind randomized controlled trial, lasting for 15 days for each participant. Patients with post-stroke dysphagia who receive treatment at the Rehabilitation Department are selected as the study subjects. The patients are randomly assigned to either the experimental group or the placebo group. All patients receive routine rehabilitation therapy and swallowing rehabilitation training, along with enteral nutrition support using Intermittent Oro-esophageal Tube. In addition to these interventions, patients in the experimental group receive transcranial direct current stimulation, while the instruments used for patients in the placebo group only illuminate an indicator light without any actual effect. conditions: Cerebral Infarction studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 84 type: ESTIMATED name: Comprehensive rehabilitation therapy name: Intermittent Oro-esophageal Tube Feeding name: Transcranial direct current stimulation measure: Penetration Aspiration Scale measure: Functional Oral Intake Scale measure: Swallowing Quality of Life Questionnaire measure: Patient Health Questionnaire-9 measure: Body weight measure: Nutritional status-total protein measure: Nutritional status-albumin sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Center Rehabilitation Hospital status: RECRUITING city: Seoul country: Korea, Republic of name: Wei Liu, Master role: CONTACT lat: 37.566 lon: 126.9784 hasResults: False
nctId: NCT06265766 id: NL85511.041.24 id: 85511 type: OTHER domain: ABR number briefTitle: Brain STimulation for Arm Recovery After Stroke 2 acronym: B-STARS2 overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2029-03-31 date: 2029-12-31 date: 2024-02-20 date: 2024-02-20 name: Jord Vink class: OTHER briefSummary: Rationale: Every year, about 40,000 people in the Netherlands have a stroke. After the initial admission to the hospital, about 15% of stroke survivors is admitted to a rehabilitation center because of remaining disabilities. Three out of four of these patients have upper limb dysfunction, hampering activities of daily living. Upper limb function plays a critical role in the performance of most daily life activities. In our phase II trial B-STARS, continuous theta burst stimulation (cTBS) treatment led to an absolute additional recovery of upper limb function of 17%, as measured with the Action Research Arm Test (ARAT) score three months after stroke. This improvement exceeds the minimal clinically important difference of 10%. cTBS treatment also resulted in a significant improvement in measures of activities and participation (of similar magnitude) and a reduction in the mean length of stay at the rehabilitation center by 18 days.
nctId: NCT06265753 id: Gastrocimemius spasticity id: E-60116787-020-474196 type: REGISTRY domain: Pamukkale University Ethics Comitee briefTitle: Gastrocinemius Function Massage on Lower Extemity Spasticity acronym: Spasticity overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-23 date: 2024-06-01 date: 2024-09-01 date: 2024-02-20 date: 2024-02-20 name: Pamukkale University class: OTHER briefSummary: This study aimed to investigate gastrocinemius function massage on physical parameters of stroke patients. conditions: Stroke conditions: Stroke Ischemic studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: In the study, 2 different groups (experimental and control) will be formed by using randomisation method. In addition to 45 minutes of classical physiotherapy exercises, 10 minutes of gastrocinemius function massage will be applied to the experimental group, while 10 minutes of sham massage and 45 minutes of classical physiotherapy exercises will be applied to the control group. The application will continue 2 days a week for 6 weeks. Spasticity, gait parameters and fall risks of the participants will be evaluated before and after the treatment with the help of various tests.
Translated with www.DeepL.com/Translator (free version) primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 28 type: ESTIMATED name: Gastrocinemius Function Massage name: Sham application measure: Spasticity measure: Gait parameters and fall risk sex: ALL minimumAge: 18 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University Address city: Denizli state: Muş Alparslan University zip: 20100 country: Turkey lat: 37.77417 lon: 29.0875 hasResults: False
nctId: NCT06265740 id: RBHP 2023 GALLOT (PREMABIOTE) id: 2023-A02466-39 type: OTHER domain: 2023-A02466-39 briefTitle: Early Diagnosis of Premature Births by Analysis of the Vaginal Microbiota acronym: PREMABIOTE overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-11 date: 2025-11 date: 2024-02-20 date: 2024-02-20 name: University Hospital, Clermont-Ferrand class: OTHER briefSummary: Objectives: to assess the relevance of the "RiboTaxa" algorithm coupled with neural network learning based on analysis of vaginal microbiota metagenomic sequencing data for predicting prematurity in an identified at-risk population.
Study description: Longitudinal follow-up of a cohort of pregnant women, with collection of biological samples, and a posteriori case-control comparison based on the occurrence of an event (premature birth). conditions: Premature Birth conditions: Vaginal Flora studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 150 type: ESTIMATED name: vaginal swab measure: Early diagnosis of preterm birth using vaginal microbiota analysis sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: CHU de Clermont-Ferrand city: Clermont-Ferrand country: France name: Lise Laclautre role: CONTACT name: Denis Gallot role: PRINCIPAL_INVESTIGATOR lat: 45.77966 lon: 3.08628 hasResults: False
nctId: NCT06265727 id: CRB-701-01 briefTitle: A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors overallStatus: RECRUITING date: 2024-04-01 date: 2027-01-16 date: 2027-01-27 date: 2024-02-20 date: 2024-04-09 name: Corbus Pharmaceuticals Inc. class: INDUSTRY name: CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. briefSummary: The goal of this clinical trial is to define a safe and effective dose of CRB-701 for participants with solid tumors that are expressing a protein called nectin-4.
nctId: NCT06265714 id: LB.02.01/VII/005/KEP005/2022 briefTitle: The IndONEsia ICCU Registry: a Multicenter Cohort of Intensive Cardiovascular Care Units Patients in Indonesia overallStatus: COMPLETED date: 2021-07-23 date: 2023-09-06 date: 2023-09-23 date: 2024-02-20 date: 2024-02-20 name: Indonesia University class: OTHER briefSummary: Patients in the Intensive Cardiovascular Care Unit (ICCU) often present with cardiovascular disease (CVD) issues accompanied by various non-cardiovascular conditions. However, a widely applicable scoring system to predict patient outcomes in the ICCU is lacking. Therefore, developing and validating scores for predicting ICCU patient outcomes are warranted. The aims of the IndONEsia ICCU (One ICCU) registry include developing an epidemiological registry of ICCU patients and establishing a multicentre research network to analyse patient outcomes.This nationwide multicenter cohort will capture data from patients receiving cardiovascular critical care treatment in 10 Indonesian hospitals with ICCU facilities. Recorded data will encompass demographic characteristics, physical examination findings at hospital and ICCU admission, diagnoses at ICCU admission, therapy, intervention, complications on days 3 and 5 of in-ICCU care, in-hospital outcomes, and 30-day outcomes. The One ICCU is a large, prospective registry describing the care process and advancing clinical knowledge in ICCU patients. It will serve as an investigational platform for predicting the mortality of ICCU patients. conditions: Cardiovascular Diseases conditions: Acute Coronary Syndrome conditions: Heart Failure conditions: Heart Disease, Coronary conditions: Infections conditions: Sepsis conditions: Stroke conditions: Shock conditions: Chronic Kidney Diseases studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 12950 type: ACTUAL measure: Alive measure: Death measure: Readmitted to ICCU measure: Rehospitalization sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Prof. dr. I.G.N.G. Ngoerah General Hospital city: Denpasar state: Bali country: Indonesia lat: -8.65 lon: 115.21667 facility: Dr. Kariadi General Hospital city: Semarang state: Central Java country: Indonesia lat: -6.99306 lon: 110.42083 facility: Dr. Saiful Anwar General Hospital city: Malang state: East Java country: Indonesia lat: -7.9797 lon: 112.6304 facility: Dr. Iskak General Hospital city: Tulung Agung state: East Java country: Indonesia lat: -5.3578 lon: 105.04623 facility: Prof. Dr. R. D. Kandou Manado General Hospital city: Manado state: North Sulawesi country: Indonesia lat: 1.48218 lon: 124.84892 facility: Dr. Wahidin Sudirohusodo General Hospital city: Makassar state: South Sulawesi country: Indonesia lat: -5.14861 lon: 119.43194 facility: Dr. M. Djamil Padang General Hospital city: Padang state: West Sumatra country: Indonesia lat: -0.94924 lon: 100.35427 facility: National Cardiovacular Center Harapan Kita city: Jakarta country: Indonesia lat: -6.21462 lon: 106.84513 facility: Sardjito General Hospital city: Yogyakarta country: Indonesia lat: -7.80139 lon: 110.36472 hasResults: False
nctId: NCT06265701 id: IRB0148200 briefTitle: Does a Novel Intervention Targeting Derailment Decrease Depressive Symptoms? overallStatus: ACTIVE_NOT_RECRUITING date: 2024-02-15 date: 2024-03-12 date: 2024-03-12 date: 2024-02-20 date: 2024-03-13 name: Cornell University class: OTHER briefSummary: The goal of this clinical trial is to explore the efficacy of a reflective journaling intervention-"Me Through Time"- in decreasing levels of derailment, and its impact on downstream depressive symptoms. conditions: Depression conditions: Depressive Symptoms conditions: Derailment conditions: Anxiety studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Investigators will utilize a single-blind approach where participants will not be made aware of the purpose of the intervention. Participants in both arms will be told that the purpose of the study is "to determine the efficacy of a novel five-session journaling intervention, which explores concepts related to self-continuity". This is partly true for those in the experimental arm. The main purpose of the study is twofold: (1) to explore the efficacy of the experimental journaling intervention's in reducing levels of derailment and (2) to test the hypothesis that decreasing derailment- a temporal discordance of the self- will lead to a decrease in depressive symptoms. whoMasked: PARTICIPANT count: 116 type: ACTUAL name: Derailment-Focused Reflective Journaling name: Everyday Tasks Reflective Journaling measure: Change from Pre-Assessment in Depressive Symptoms on the Beck Depression Inventory II (BDI-II) at Week 2 (Session 6/Post-Assessment) measure: Change from Pre-Assessment in Levels of Derailment on the Derailment Scale at Session 5 measure: Change from Pre-Assessment in Anxiety Symptoms on the Generalized Anxiety Disorder - 7 (GAD-7) at Week 2 (Session 6/Post-Assessment) measure: Change from Pre-Assessment in Levels of Positive and Negative Affect on the Positive and Negative Affect Schedule (PANAS) at Week 2 (Session 6/Post-Assessment) measure: Change from Pre-Assessment in Levels of Perceived Stress on the Perceived Stress Scale (PSS) at Week 2 (Session 6/Post-Assessment) measure: Change from Pre-Assessment in Levels of Optimism Versus Pessimism on the Life Orientation Test - Revised (LOT - Revised) at Week 2 (Session 6/Post-Assessment sex: ALL minimumAge: 18 Years maximumAge: 29 Years stdAges: ADULT facility: Cornell University city: Ithaca state: New York zip: 14850 country: United States lat: 42.44063 lon: -76.49661 hasResults: False
nctId: NCT06265688 id: CTMX-2051-101 briefTitle: First In Human Study of CX-2051 in Advanced Solid Tumors overallStatus: RECRUITING date: 2024-04-02 date: 2027-11-30 date: 2029-03-31 date: 2024-02-20 date: 2024-04-18 name: CytomX Therapeutics class: INDUSTRY briefSummary: The purpose of this first-in-human study, CTMX-2051-101, is to characterize the safety, tolerability, and antitumor activity of CX-2051 in adult participants with advanced solid tumors. conditions: Solid Tumor, Adult studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 124 type: ESTIMATED name: CX-2051 measure: Safety and tolerability of CX-2051 measure: Determine the recommended Phase 2 dose (RP2D) measure: Objective response rate (ORR) measure: Duration of response (DOR) measure: Progression-free survival (PFS) measure: Disease control rate (DCR) measure: Duration of disease control (DODC) measure: Overall survival (OS) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Dana-Farber Cancer Institute status: NOT_YET_RECRUITING city: Boston state: Massachusetts zip: 02215 country: United States lat: 42.35843 lon: -71.05977 facility: Carolina BioOncology Institute, PLLC status: RECRUITING city: Huntersville state: North Carolina zip: 28078 country: United States lat: 35.41069 lon: -80.84285 facility: Sarah Cannon Research Institute, LLC status: RECRUITING city: Nashville state: Tennessee zip: 37203 country: United States lat: 36.16589 lon: -86.78444 hasResults: False
nctId: NCT06265675 id: E1-4066/2023 briefTitle: Comparison of the Efficacy of Phenol Block and Corticosteroid-Local Anesthetic Block Applied to the Genicular Nerve overallStatus: RECRUITING date: 2024-01-24 date: 2025-01-24 date: 2025-06-24 date: 2024-02-20 date: 2024-02-20 name: Gaziler Physical Medicine and Rehabilitation Education and Research Hospital class: OTHER briefSummary: There are different neurolysis methods. Aim of this study is to compare two different methods, phenol block and corticosteroid local anesthetic block. conditions: Knee Osteoarthritis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 88 type: ESTIMATED name: Phenol name: Celestone name: Lidocain measure: Numeric Rating Scale (NRS) measure: Western Ontario and McMaster Universities Arthritis Index (WOMAC) measure: Patient Global Impression of Change (PGIC) measure: Sixt Minute Walk Test (6MWT) measure: The Timed-Up and Go test measure: Frequency of analgesic usage sex: ALL minimumAge: 50 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Gaziler status: RECRUITING city: Ankara state: Çankaya country: Turkey name: Rabia Layık, Assist. Dr. role: CONTACT lat: 39.91987 lon: 32.85427 hasResults: False