hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06381336 id: TRAKSILVER2022 briefTitle: A Digital Home-Based Physiotherapy Program for Active Aging acronym: TRAK overallStatus: COMPLETED date: 2022-03-23 date: 2022-11-07 date: 2022-11-07 date: 2024-04-24 date: 2024-04-25 name: Trak Health Solutions S.L. class: INDUSTRY name: Basque Health Service name: University of the Basque Country (UPV/EHU) briefSummary: This clinical trial will aim to understand the effects of the TRAK-SILVER digital platform on pre-frail and older adults living at home, assessing its impact on physical activity level, emotional variables, and overall quality of life. Participant satisfaction with the digital treatment will also be evaluated.
The participants will undergo a 3-month physiotherapy program using the TRAK-SILVER platform or a paper guide based on their assigned group. Additionally, weekly uploads of health-promoting audiovisual content will enhance the intervention's holistic approach to improving older adults' well-being and functional capacity. conditions: Frail Elderly Syndrome conditions: Older Adults studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: A randomized two-group design with pretest-posttest assessment was used to analyse the effectiveness of the TRAK-SILVER application. Seventy-two adults aged 65 and above were stratified by gender and physical functioning capacity (SPBB) and then randomly assigned to either the experimental (EG) or control group (CG). EG received the TRAK-SILVER platform as a treatment methodology. The CG did not have access to the platform and was instructed to continue with the standard care program through exercise sheets. primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 72 type: ACTUAL name: TRAK-SILVER platform measure: Short Physical Performance Battery (SPPB measure: Gait Speed measure: Timed Up and Go Test measure: 6-minute walk test (6MWT) measure: Berg Balance Scale measure: Number of steps count measure: Geriatric Depression Scale-15 (GDS) measure: De Jong Gierveld Loneliness Scale (JGLS) measure: Quality of life (QoL) questionnaire measure: Client Satisfaction Questionnaire (CSQ) sex: ALL minimumAge: 65 Years stdAges: OLDER_ADULT facility: Social Center of Orio (Zahartzaroa) city: Orio state: Basque Country zip: 20810 country: Spain lat: 43.2787 lon: -2.12537 hasResults: False
nctId: NCT06381323 id: PA2024 briefTitle: The Clinical Efficacy and Safety of Finerenone in the Treatment of Primary Aldosteronism overallStatus: RECRUITING date: 2024-03-01 date: 2027-03-01 date: 2027-04-01 date: 2024-04-24 date: 2024-04-24 name: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School class: OTHER briefSummary: The purpose of our research is to clarify the therapeutic efficacy and safety of Finerenone in patients with Primary Aldosteronism and explore the effective clinical predictive indicators of Finerenone in the treatment of Primary Aldosteronism. conditions: Primary Aldosteronism conditions: Finerenone conditions: Mineralocorticoid Receptor Antagonist studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 55 type: ESTIMATED name: Finerenone measure: 24h systolic BP drop value measure: The change of diastolic BP from the baseline level after Finerenone treatment measure: Hypertension remission rate measure: Change of serum potassium level measure: Change of plasma renin activity measure: Change of ARR measure: Change of UACR measure: Change of eGFR measure: Incidence of Treatment-Adverse Events as assessed by gynaecomastia, mastodynia, menstrual abnormalities, impotence, hyperkalemia and other adverse events. sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Endocrinology, Drum Tower Hospital affiliated to Nanjing University Medical School status: RECRUITING city: Nanjing state: Jiangsu zip: 210008 country: China name: Dalong Zhu, MD,PhD role: CONTACT phone: 86-25-83-105302 email: zhudalong@nju.edu.cn name: Ping Li, MD,PhD role: CONTACT phone: 86-25-83-105302 email: li78321@yeah.net name: Dalong Zhu, MD,PhD role: PRINCIPAL_INVESTIGATOR name: Ping Li, MD,PhD role: SUB_INVESTIGATOR lat: 32.06167 lon: 118.77778 hasResults: False
nctId: NCT06381310 id: 202310077DINB briefTitle: Ultrasound-guided Cannulation of Difficult Hemodialysis Arteriovenous Access overallStatus: RECRUITING date: 2024-02-26 date: 2024-10-30 date: 2024-10-30 date: 2024-04-24 date: 2024-04-24 name: National Taiwan University Hospital class: OTHER name: National Taiwan University Hospital Bei-Hu Branch briefSummary: Patients with ESRD are able to maintain life by undergoing renal replacement therapy, including hemodialysis (HD), peritoneal dialysis (PD) or kidney transplantation. HD continues to be the primary option. Arteriovenous fistula (AVF) and arteriovenous graft (AVG) are the common access sites for hemodialysis (HD) patients. AVF is the best access for dialysis , which is known as the lifeline of hemodialysis patients, but requires 6 to 8 weeks to maturate. Long-term use of an AVF for dialysis requires the ability of the dialysis staff to cannulate it successfully with large-bore needles thrice weekly. With increasing AVF prevalence as well as aging and more obese populations in the developed world, increasing numbers of difficult-to-cannulate AVFs are being encountered in practice.
Traditionally, after maturation, cannulation of new AVF/AVG was performed by trained renal nurses through physical examination, namely listening to bruits and feeling for thrills to guide needle placement, known as "blind" cannulatio. However, physical examination is not reliable for first and difficult access cannulation (e.g., small or partial stenosis, deep-seated AVF/AVG, presence of clots, after multiple failed attempts with hematoma /swelling, and/or immature access with small vessel caliber), rendered higher rate of cannulation failure and lower AVF and AVG survival. Unfortunately, cannulation failure result in access damage, vessel intimal lining damage leading to stenosis, thrombosis, or aneurysm formation contributing to AVF failure, treatment delay and increased requirement for central venous access devices (CVAD). Patients with early AVF failure have much higher mortality risk, particularly if they are older and female. Van Loon et al. revealed that up to 90% of the first cannulation had complications (i.e., infiltration including hematoma formation and missed cannulation). With a high rate of AVF maturation failure (38-60%) in general, cannulation failure may be avoidable if a more in-depth assessment was done before the attempt.
Therefore, this study aims to explore the effects of ultrasound technology on arteriovenous access successful cannulation for patients with end-stage kidney disease to provide reliable research integration evidence as the basis for future clinical care. conditions: Successful Cannulation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 50 type: ESTIMATED name: asus-handheld-ultrasound LU710L measure: cannulation success rate measure: cannulation satisfaction sex: ALL minimumAge: 20 Years maximumAge: 90 Years stdAges: ADULT stdAges: OLDER_ADULT facility: National Taiwan University Hospital Bei-Hu Branch status: RECRUITING city: Taipei City country: Taiwan name: Tsuei-Wun Chang role: CONTACT phone: 886-23717101 phoneExt: 218501 lat: 25.04776 lon: 121.53185 hasResults: False
nctId: NCT06381297 id: OndokusMU id: Ondokuz Mayıs University type: REGISTRY domain: Clinical research ethics committee briefTitle: Speech in Noise Discrimination Skills in Multiple Sclerosis Patients. overallStatus: COMPLETED date: 2020-10-09 date: 2023-03-23 date: 2023-04-23 date: 2024-04-24 date: 2024-04-24 name: Asuman Kucukoner class: OTHER briefSummary: The aim of this clinical trial was to determine the effect of multiple sclerosis on speech reception and discrimination in noise and to compare the effects on the medial olivocochlear reflex, which is thought to affect speech intelligibility in noise, with a control group.
Does MS disease affect the ability to discriminate speech in noise? Does MS affect contralateral suppression results assessing medial olivocochlear function? Is there a correlation between the ability to discriminate speech in noise and contralateral suppression skills of MS patients? Data from MS patients and healthy participants will be compared. Thirty relapsing remitting MS patients and 30 healthy participants admitted to the clinic will be evaluated. conditions: Multiple Sclerosis-Relapsing-Remitting studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: Multiple sclerosis patient group and healthy control group. primaryPurpose: DIAGNOSTIC masking: NONE count: 60 type: ACTUAL name: Hearing test name: Speech in noise discrimination test name: Montreal Cognitive Assessment Scale name: Symbol Number Modalities Test (SDMT) measure: Pure tone Audiometry Test measure: Speech Audiometry measure: Speech Discrimination in Noise Test measure: Otoacoustic Emission Test measure: Contralateral Suppression Test measure: Montreal Cognitive Assessment Scale measure: Symbol Digit Modalities Test sex: ALL minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Ondokuz Mayıs University city: Samsun zip: 55300 country: Turkey lat: 41.27976 lon: 36.3361 hasResults: False
nctId: NCT06381284 id: MG-001 briefTitle: Feasibility of Engaging and Capturing Undiagnosed Myasthenia Gravis Participants Through a Social Media Campaign Paired With a Self-moderated Assessment overallStatus: RECRUITING date: 2024-03-28 date: 2024-05-27 date: 2025-05-27 date: 2024-04-24 date: 2024-04-26 name: ZS Associates class: INDUSTRY name: University of California, San Francisco briefSummary: This is a fully remote, site-less, prospective, observational study enrolling adults in the United States (excluding U.S. territories) with undiagnosed neuromuscular symptoms. The main study objective is to evaluate the feasibility of a social media recruitment campaign tied to a participant reported symptom survey and self-administered physical assessment tool to influence undiagnosed participants to seek care for suspected Myasthenia Gravis (MG). conditions: Myasthenia Gravis conditions: Neuromuscular Manifestations conditions: Neuromuscular Diseases studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 1000 type: ESTIMATED name: Social media recruitment name: Self-Assessment name: Follow-up measure: Social media recruitment feasibility measure: MG Exercise Assessment Tool validity measure: Time to diagnosis sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: ZS Associates status: RECRUITING city: Evanston state: Illinois zip: 60201 country: United States name: Ananda V Pandurangadu, MD role: CONTACT phone: 1-847-448-1001 email: support@unearthrootcause.com name: Ananda Vishnu Pandurangadu, MD role: PRINCIPAL_INVESTIGATOR name: Pritikanta Paul, MD role: SUB_INVESTIGATOR lat: 42.04114 lon: -87.69006 hasResults: False
nctId: NCT06381271 id: TRUST TAVR Registry briefTitle: Transcatheter Aortic Valve Replacement for Pure Severe Aortic Valve Regurgitation overallStatus: RECRUITING date: 2018-10-30 date: 2034-10 date: 2034-10 date: 2024-04-24 date: 2024-04-24 name: Xijing Hospital class: OTHER briefSummary: The purpose of this multicenter, prospective and observational registry is to evaluate the safety and efficacy of TAVR for treatment of pure severe aortic valve regurgitation. Baseline characteristics, procedural and clinical data will be collected conditions: Aortic Valve Regurgitation studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 500 type: ESTIMATED name: Transcatheter aortic valve replacement measure: Combined clinical efficacy outcomes measure: Combined early safety and clinical efficacy outcomes measure: Rate of technical success measure: Rate of device success measure: Combined clinical efficacy outcomes measure: Rate of all-cause mortality measure: Valve-related long-term clinical efficacy sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Xijing Hospital status: RECRUITING city: Xi'an state: Shannxi zip: 710032 country: China name: Rutao Wang, M.D., Ph.D. role: CONTACT phone: +86-15091095796 email: rutaowang@qq.com name: Ruining Zhang, BSc role: CONTACT phone: +86-15802990370 email: ruining-zhang@qq.com name: Ling Tao, M.D., Ph.D. role: PRINCIPAL_INVESTIGATOR lat: 34.25833 lon: 108.92861 hasResults: False
nctId: NCT06381258 id: SDF briefTitle: Fetal Cardiac Function overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-10 date: 2024-11 date: 2024-04-24 date: 2024-04-24 name: Assiut University class: OTHER briefSummary: The aim of our study is to evaluate the effect of PE and FGR on fetal cardiac function. Pregnancies with preeclampsia and FGR, and preeclampsia with normal fetal growth are evaluated by echocardiography and compared with uncomplicated pregnancies. conditions: Fetal Growth Retardation studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 32 type: ESTIMATED name: Ultrasound measure: Cardiac systolic function measure: Cardiac diastolic function sex: FEMALE stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06381245 id: KB/265/2023 briefTitle: First-time Ablation of Atrial Fibrillation Registry acronym: DIPE overallStatus: RECRUITING date: 2023-12-01 date: 2026-03-31 date: 2026-03-31 date: 2024-04-24 date: 2024-04-24 name: Medical University of Warsaw class: OTHER briefSummary: Atrial fibrillation (AF) is a prevalent cardiac arrhythmia affecting millions globally, with projections indicating a doubling of cases by 2050. AF is linked to heightened cardiovascular risks like stroke and increased healthcare costs. Ablation, targeting the arrhythmia substrate, is a method to manage AF, yet recurrence rates remain high (20-45% in the first year). Studies highlight the impact of comorbidities, AF characteristics, ablation techniques, and myocardial remodeling markers on AF progression and ablation efficacy. However, there's no definitive guidance on selecting these factors for predicting treatment success.
The aim of this study is to investigate predictors of successful AF ablation in the following areas: (a) clinical factors, (b) electrophysiological, (c) electrocardiographic, (d) ultrasound, (e) cardiac anatomy, (f) biomarkers. conditions: Atrial Fibrillation conditions: Arrhythmia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 400 type: ESTIMATED name: PPG-based remote heart rhythm/rate monitoring name: ECG-based remote heart rhythm/rate monitoring name: Transthoracic and transesophageal echocardiography examination name: Liver ultrasound examination name: Rotational angiography with three-dimensional reconstruction name: Blood-derived biomarker analysis name: Mobile health-based spirometry measure: Late AF recurrence measure: Late recurrence of AF or atrial tachycardia or atrial flutter measure: Early recurrence of AF measure: Early recurrence of AF or atrial tachycardia or atrial flutter measure: Time to AF recurrence and the impact of early recurrence on late AF recurrence measure: The superiority of monitoring using mobile health devices over traditional heart rhythm monitoring measure: Progression or regression of AF measure: Modification of treatment, including antiarrhythmic treatment measure: AF-related quality of life and symptoms measure: Periprocedural complications measure: Heart rate variability and rate measure: Blood biomarker levels measure: Ablation procedure parameters measure: Cardiac remodelling sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Medical University of Warsaw status: RECRUITING city: Warsaw country: Poland name: Monika Gawałko, MD, PhD role: CONTACT phone: 22 599 19 58 phoneExt: +48 email: monika.gawalko@wum.edu.pl name: Monika Gawałko, MD, PhD role: PRINCIPAL_INVESTIGATOR name: Paweł Balsam, MD, PhD role: PRINCIPAL_INVESTIGATOR name: Piotr Lodziński, MD, PhD role: SUB_INVESTIGATOR name: Michał Marchel, MD, PhD role: SUB_INVESTIGATOR name: Michał Peller, MD, PhD role: SUB_INVESTIGATOR name: Bartosz Krzowski, MD, PhD role: SUB_INVESTIGATOR name: Cezary Maciejewski, MD, PhD role: SUB_INVESTIGATOR name: Maria Boszko, MD role: SUB_INVESTIGATOR name: Michał Gawlik, MD role: SUB_INVESTIGATOR name: Karolina Mitrzak, MD role: SUB_INVESTIGATOR name: Alicja Skrobucha, MD role: SUB_INVESTIGATOR name: Mateusz Wawrzeńczyk, MD role: SUB_INVESTIGATOR lat: 52.22977 lon: 21.01178 hasResults: False
nctId: NCT06381232 id: VIOME-001 briefTitle: Collection and Analyses of Physiological, Physical, and Molecular Data From a Diverse Population overallStatus: RECRUITING date: 2018-07-23 date: 2028-07-23 date: 2028-07-23 date: 2024-04-24 date: 2024-04-24 name: Viome class: INDUSTRY briefSummary: The purpose of the study is to collect and analyze physiological, physical, and molecular data from a diverse population to increase our understanding of how such parameters are associated with health and disease. conditions: General Health conditions: Wellness studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 20000 type: ESTIMATED name: No Intervention measure: Molecular Determinants of Health and Disease sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Viome Life Sciences status: RECRUITING city: Bothell state: Washington zip: 98011 country: United States name: Momchilo Vuyisich role: CONTACT phone: 425-300-6933 email: studies@viome.com lat: 47.76232 lon: -122.2054 hasResults: False
nctId: NCT06381219 id: s67001 briefTitle: Pediatric Eosinophilic Esophagitis (pedEoE): Effect of Allergen Heat Denaturation on EoE Remission: a Pilot Trial overallStatus: RECRUITING date: 2023-12-19 date: 2026-12-31 date: 2028-12-31 date: 2024-04-24 date: 2024-04-24 name: Universitaire Ziekenhuizen KU Leuven class: OTHER briefSummary: The objective of the study is to study whether the introduction of heated food products (more specifically heated hen's egg and/or cow's milk) in children with EoE would be possible without re-occurrence of the eosinophilic inflammation, while the intake of less heated products might cause disease recidive. Moreover, we would like to study whether the gradual re-introduction of less heated products after the most heated form is tolerated, could lead to tolerance induction in EoE. conditions: Eosinophilic Esophagitis studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: DIAGNOSTIC masking: NONE count: 36 type: ESTIMATED name: Implementation of cow's milk in decreasingly heated forms name: Implementation of hen's egg in decreasingly heated forms measure: Maintained remission of EoE measure: Maintained remission only in step 1 of the diet measure: Association of remission with circulating IgG4 levels measure: Association of remission with IgG4 levels on biopsy measure: In vitro B cell test to mimic B cell activation after stimulation measure: Correlation between QoL and remission measure: Associated atopy measure: Associated food allergies sex: ALL minimumAge: 12 Months maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: UZ Leuven Gasthuisberg status: RECRUITING city: Leuven state: Vlaams-Brabant zip: 3000 country: Belgium name: Dominique Bullens, Prof. Dr. role: CONTACT phone: 0032 16 34 38 01 email: dominique.bullens@kuleuven.be name: Marleen Jannis role: CONTACT phone: 0032 16 34 38 01 email: marleen.jannis@uzleuven.be lat: 50.87959 lon: 4.70093 typeAbbrev: Prot hasProtocol: True hasSap: False hasIcf: False label: Study Protocol date: 2023-07-05 uploadDate: 2023-10-25T10:35 filename: Prot_000.pdf size: 696874 hasResults: False
nctId: NCT06381206 id: No 475 briefTitle: Silodosin in Management of Lower Ureteral Stones overallStatus: COMPLETED date: 2022-10-20 date: 2023-10-20 date: 2023-10-25 date: 2024-04-24 date: 2024-04-24 name: Syrian Private University class: OTHER briefSummary: This research aims to study the effectiveness of silodosin in the management of lower ureter stones larger than 6 mm in diameter in terms of affected ureter (right or left), the size of the stone, the degree of hydronephrosis, the rate of stone expulsion(day), whether the stone was completely expelled or not, and the side effects of silodosin. conditions: Stone, Kidney studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 100 type: ACTUAL name: Silodosin measure: Stone expulsion (yes) measure: Stone expulsion (no) sex: ALL minimumAge: 20 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Damascus university city: Damascus zip: 1 country: Syrian Arab Republic lat: 33.5102 lon: 36.29128 hasResults: False
nctId: NCT06381193 id: ESTR-01-2022 briefTitle: Study for the Management of Chronic and Functional Constipation Through the Intake of Probiotics and Prebiotics overallStatus: COMPLETED date: 2023-03-03 date: 2023-07-10 date: 2023-07-10 date: 2024-04-24 date: 2024-04-24 name: Centros de Investigación de Nutrición y Salud class: OTHER name: Nutribiotica briefSummary: The goal of this clinical trial is to learn if supplementation with prebiotics and/or probiotics can lead to an improvement in symptoms of patients with functional constipation. The main objectives are:
Participants took 4 units of product per day (2 of each assigned product) for 2 months. conditions: Functional Constipation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 80 type: ACTUAL name: Probiotic name: Prebiotic name: Probiotic + Prebiotic name: Placebo measure: 1. To evaluate the effect of the dietary supplements on the bowel frequency movements in patients with chronic functional constipation. measure: To evaluate the stool consistency (Bristol scale). measure: To evaluate the quality of life scale score for patients with constipation (Quality of life questionnaire for patients with constipation, CVE-20) measure: To evaluate the quality of life scale score for patients with constipation (Gastrointestinal Symptom Assessment Scale, GSRS scale). sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Centros de Investigación en Nutrición y Salud SL. (Clínica CINUSA) city: Madrid zip: 28036 country: Spain lat: 40.4165 lon: -3.70256 hasResults: False
nctId: NCT06381167 id: Endoscopic decompression briefTitle: Endoscopic Decompression Versus Microscopic Decompression in Lumbar Canal Stenosis overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2027-05 date: 2027-10 date: 2024-04-24 date: 2024-04-24 name: Assiut University class: OTHER briefSummary: To compare between the clinical and surgical efficacies of bi-portal endoscopic and microscopic decompressive laminectomy in patients with degenerative lumbar spinal stenosis. conditions: Lumbar Spinal Stenosis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: NONE count: 52 type: ESTIMATED name: Endoscopic Decompressive Laminectomy measure: Oswestry Disability Index ODI scores for low back pain and neuropathic pain measure: visual analog scale (VAS) score for low back and lower extremity radiating pain measure: European Quality of Life-5 Dimensions (EQ-5D) score measure: painDETECT score sex: ALL minimumAge: 40 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False