hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06340178 id: 2024-00246 briefTitle: CT-guided Lung Biopsy Risk Optimization Method acronym: BROM-I overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2027-04-01 date: 2024-04-01 date: 2024-04-01 name: Insel Gruppe AG, University Hospital Bern class: OTHER briefSummary: The purpose of this randomized controlled study is to evaluate the extent to which injection of a small amount of fluid in the pleural cavity at the biopsy site may reduce the risk of pneumothoraces, in addition to patient positioning to allow biopsy in gravity-dependent areas of the lung. conditions: Pneumothorax conditions: Biopsy, Needle conditions: Risk Factors conditions: Radiology, Interventional studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 198 type: ESTIMATED name: Fluid application during ct-guided lung biopsy measure: Number of patients with pneumothorax measure: Number of patients with bleeding measure: Number of patients with chest tube placement measure: Number of patients with air embolism sex: ALL minimumAge: 18 Years maximumAge: 100 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 10 city: Bern zip: 3010 country: Switzerland lat: 46.94809 lon: 7.44744 hasResults: False
nctId: NCT06340165 id: 2023-KS-151 briefTitle: A Real-world Efficacy and Safety Study of Amlotinib for HER2-negative Advanced Breast Cancer overallStatus: RECRUITING date: 2024-02-04 date: 2025-06 date: 2025-06 date: 2024-04-01 date: 2024-04-01 name: The First Hospital of Jilin University class: OTHER briefSummary: This study analyses the efficacy and safety of amlotinib as a study drug in the treatment of HER-2 negative advanced breast cancer in the real world, including the number of treatment lines, monotherapy, combination therapy, and different molecular subtypes of breast cancer. Evidence-based medicine evidence for clinicians. Although the clinical application of amlotinib in breast cancer treatment is a supra-indication drug, in view of its high safety and possible good efficacy for advanced breast cancer, some patients have been clinically adopted to try the treatment after communicating with their families. This study provides evidence for the further use of amlotinib in breast cancer treatment by analysing the efficacy and safety of amlotinib in real-world applications. conditions: Breast Cancer studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: RETROSPECTIVE count: 153 type: ESTIMATED name: Anlotinib measure: PFS sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: The First Affiliated Hospital of Jilin University status: RECRUITING city: Changchun state: Jilin zip: 130021 country: China name: xu sun role: PRINCIPAL_INVESTIGATOR lat: 43.88 lon: 125.32278 hasResults: False
nctId: NCT06340152 id: 808385 id: U01HG013189-01 type: NIH link: https://reporter.nih.gov/quickSearch/U01HG013189-01 briefTitle: Multi-Omics for Maternal Health After Preeclampsia acronym: MOM-Health overallStatus: RECRUITING date: 2023-12-20 date: 2028-12 date: 2028-12 date: 2024-04-01 date: 2024-04-01 name: University of California, San Diego class: OTHER name: National Human Genome Research Institute (NHGRI) name: Vanderbilt University Medical Center briefSummary: To develop strategies to identify postpartum women at risk for adverse cardiovascular outcomes and provide them with preventative therapies. conditions: Pre-Eclampsia conditions: Pregnancy Induced Hypertension studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 1100 type: ESTIMATED measure: Preeclampsia measure: Gestational hypertension measure: Postpartum hypertension measure: Postpartum cardiovascular disease measure: Other cardiovascular disease sex: FEMALE minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: University of California, San Diego status: RECRUITING city: San Diego state: California zip: 92037 country: United States name: Samantha La Belle role: CONTACT phone: 858-249-5985 email: slabelle@health.ucsd.edu name: Louise Laurent, MD, PhD role: PRINCIPAL_INVESTIGATOR name: Marni Jacobs, PhD role: PRINCIPAL_INVESTIGATOR lat: 32.71533 lon: -117.15726 hasResults: False
nctId: NCT06340139 id: Riphah/RCRAHS-ISB/REC/01742 briefTitle: Vestibulo-Ocular Reflex for Balance and Stimming in Autism Spectrum Disorder overallStatus: RECRUITING date: 2024-03-20 date: 2024-07-20 date: 2024-08-20 date: 2024-04-01 date: 2024-04-01 name: Riphah International University class: OTHER briefSummary: Autism spectrum disorder is a neurodevelopmental disorder that encompasses a number of disorders specifically affecting social skills, Communication and present with Rapid repetitive behaviors. Autism spectrum disorder also presents with inability of body to process sensory information which can causes symptoms such as balance deficits, sensitivity to certain sounds or an exaggerated reaction to a normal stimulus. Autism spectrum disorder can affect the quality of life of an individual to a severe extent. This disorder due to sensory processing deficits also shows difficulty in motor planning, coordination and execution of tasks which can make performing activities of daily living highly difficult to perform. It is called a developmental disorder because it affects the growth. Milestones are often delayed in individuals with autism. Due to these deficits individual with autism if not provided with therapies at the right age can stay dependent on caretaker for their whole life. Rapid repetitive behaviors also known as self-stimulatory behaviors are a way to compensate with anxiety, difficulty in processing sensory information and are often used to stimulate themselves to feel calm. Though not a diagnostic symptom autism often still presents with vestibular dysfunction which affects the balance. Several individuals with autism have showed abnormal vestibular ocular reflexes; abnormally long latency of saccades. Rehabilitation protocol of Autism often includes symptomatic treatment and several therapy protocols such as physical therapy, occupational therapy, applied behavior analysis therapy and play therapy. conditions: Autism Spectrum Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 44 type: ESTIMATED name: conventional treatment name: experimental treatment measure: Aberrant behavior checklist measure: Berg Balance Scale (BBS) measure: Repetitive Behavior Scale - Revised measure: Functional Reach Test sex: ALL minimumAge: 13 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: zamam autism Centre status: RECRUITING city: Islamabad country: Pakistan name: Rahim Hussain role: CONTACT lat: 33.72148 lon: 73.04329 hasResults: False
nctId: NCT06340126 id: REC/RCR & AHS/23/0567 briefTitle: Effects of Active Tissue Release Techniques on Groin Pain in 2nd Trimester of Pregnancy overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-09-20 date: 2024-10-05 date: 2024-04-01 date: 2024-04-01 name: Riphah International University class: OTHER briefSummary: The study will focus on the effects of active tissue release techniques on groin pain, hip range of motion, and functional disability in 2nd trimester of pregnancy. This will be a randomized controlled trial conducted on 30 participants from Prime Care Hospital. Pregnant women in the second trimester aged between 25 to 35 years, who have groin or round ligament pain will be included in this study. A sample of 30 will be divided into 2 groups. Group A will undergo treatment of active release techniques for 10 minutes thrice a week with no home plan of home relaxation exercises. In contrast, Group B will combine treatment of active release technology with home relaxation exercises. Treatment will be given for 4 weeks and pain will be assessed before and after the treatment through (NPRS) scale. Functional disability will be measured before and after the treatment through Quebec scale and Force Disability Scale Questionnaire in both groups. conditions: Groin Strain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 30 type: ESTIMATED name: Active release techniques name: Relaxation exercises measure: Numeric Pain Rating Scale measure: The Quebec questionnaire: measure: Goniometer: To measure range of motion: sex: FEMALE minimumAge: 25 Years maximumAge: 35 Years stdAges: ADULT facility: Prime Care Hospital city: Faisalābad state: Punjab zip: 38000 country: Pakistan name: Ghulam Fatima, PhD* role: CONTACT phone: 03034073057 email: ghulam.fatima@riphah.edu.pk lat: 31.41554 lon: 73.08969 hasResults: False
nctId: NCT06340113 id: REC/RCR & AHS/23/0108 NASHIA briefTitle: Mulligan and Mckenzie Exercises Alongwith Stabilization Exercises in Patients With Chronic Neck Pain overallStatus: RECRUITING date: 2023-11-20 date: 2024-06-01 date: 2024-06-01 date: 2024-04-01 date: 2024-04-03 name: Riphah International University class: OTHER briefSummary: The goal of this \[type of study: Randomized control trial\] is to \[ compare the effectiveness of Mulligan and McKenzie Exercises along with stabilization exercises on pain, range of motion and disability \] in \[ in patients with chronic neck pain\].The main question it aims to answer is:
* Wether Mulligan is more effective or Mckenzie exercises along with stabilization exercises in the treatment of patients with chronic neck pain Group 1 will recieve Mulligan and stabilization exercises Group 2 will recieve Mckenzie and stabilization exercises conditions: Neck Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 22 type: ESTIMATED name: MCKENZIE AND STABILIZATION EXERCISES name: MULLIGAN AND STABILIZATION EXERCISES measure: Numeric pain rating scale measure: Neck Disability Index (NDI) measure: Goniometer sex: ALL minimumAge: 40 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Riphah international university status: RECRUITING city: Lahore state: Punjab zip: 54000 country: Pakistan name: Muhammad Sanaullah, MS role: CONTACT phone: 03224819253 email: muhammad.sanaullah@riphah.edu.pk lat: 31.558 lon: 74.35071 hasResults: False
nctId: NCT06340100 id: REC/MS-PT/01832 briefTitle: Association of History of Concussion With Vestibular Impairment and Cognitive Function in Sports Athletes overallStatus: RECRUITING date: 2024-03-23 date: 2024-04-23 date: 2024-06-02 date: 2024-04-01 date: 2024-04-01 name: Riphah International University class: OTHER briefSummary: This study investigates the potential relationship between prior concussions and their impact on both vestibular function and cognitive abilities in athletes participating in sports. conditions: Concussion, Mild conditions: Vestibular Impairment conditions: Cognitive Impairment studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: OTHER count: 115 type: ESTIMATED name: find association between vestibular impairment , cognitive fiunction with concussin measure: CANTU measure: Sports concussion office assesment tool 6 sex: ALL minimumAge: 18 Years maximumAge: 36 Years stdAges: ADULT facility: HAYATABAD Sports complex status: RECRUITING city: Peshawar state: Khyber Pakhtun Khawan zip: 24730 country: Pakistan name: Nadia Ishtiaq, MSOMPT role: CONTACT phone: +922486977541 email: Nadia.Ishtiaq@riphah.edu.pk name: MAHEEN GUL, MSSPT* role: CONTACT phone: +923319533510 name: Maheen Gul, MS*SPT role: PRINCIPAL_INVESTIGATOR lat: 34.008 lon: 71.57849 hasResults: False
nctId: NCT06340087 id: 706014-3 briefTitle: Impact Hesperetin in Combination With Sucrose on Blood Glucose Regulation overallStatus: RECRUITING date: 2024-03-31 date: 2024-08-31 date: 2025-03-31 date: 2024-04-01 date: 2024-04-23 name: University of Vienna class: OTHER briefSummary: The aim of this cross-over intervention study is to investigate the influence of hesperetin applied in combination with sucrose in comparison to an equally sweet-tasting sucrose-only solution and an isocaloric sucrose-only solution on markers of energy metabolism conditions: Blood Glucose Fluctuations conditions: Hunger studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: BASIC_SCIENCE masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 45 type: ESTIMATED name: 10% Sucrose name: Sucrose+ Hesperetin name: 7% Sucrose measure: Change in blood glucose concentration measure: Change in appetite score measure: Change in food intake measure: Change in regulating hormones sex: ALL minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Christian Doppler Laboratory for Taste Research status: RECRUITING city: Vienna zip: 1090 country: Austria name: Barbara Lieder, PhD role: CONTACT phone: +431427770611 email: Barbara.Lieder@univie.ac.at lat: 48.20849 lon: 16.37208 hasResults: False
nctId: NCT06340074 id: STUDY00010282 briefTitle: Helping Educational Leadership Mobilize Evidence acronym: HELM overallStatus: COMPLETED date: 2022-08-28 date: 2023-06-01 date: 2023-06-07 date: 2024-04-01 date: 2024-04-01 name: University of Washington class: OTHER briefSummary: Many universal, evidence-based prevention practices (EBPPs) have been developed to prevent SEB problems, typically in elementary schools, but progress toward widespread implementation has been slow and few efforts have been made to develop and test interventions to enhance EBPP implementation in schools. Schools leaders (e.g., principals) are key to decision making and implementation of EBPPs, and their leadership has been shown to be consistently linked to student outcomes through their intentional efforts to support teacher adoption and use of innovative programs. Helping Educational Leaders Mobilize (HELM) Evidence is a pragmatic, multifaceted, organizationally-focused implementation strategy targeting the implementation leadership and implementation climate of school buildings (through principals) to enhance the adoption and delivery of EBPPs in elementary schools. This pilot study, part of the larger HELM project to adapt and test the strategy based on an existing leadership intervention, Leadership and Organizational Change for Implementation (LOCI), will be implemented in the context of Positive Greetings at the Door (PGD), a universal school-based EBPP previously demonstrated to reduce disruptive behavior and increase academic engagement. conditions: Behavior, Child studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: SINGLE whoMasked: PARTICIPANT count: 333 type: ACTUAL name: HELM name: Implementation Attention Control (IAC) measure: Proximal Outcome: Strategic Implementation Leadership measure: Proximal Outcome: Strategic Implementation Climate measure: Proximal Outcome: Implementation Citizenship Behavior measure: Proximal Outcome: Implementation Initiative Stability measure: Implementation Outcome: Fidelity and Sustainment - Observed measure: Implementation Outcome: Fidelity and Sustainment - Self Report measure: Implementation Outcome: Reach measure: Implementation Outcome: Facilitators and Barriers to Implementation measure: Implementation Outcome: Implementation Cost measure: Student Educational Outcomes measure: Student Behavioral Outcomes sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Washington School Mental Health Assessment, Research, and Training (SMART) Center city: Seattle state: Washington zip: 98115-8160 country: United States lat: 47.60621 lon: -122.33207 hasResults: False
nctId: NCT06340061 id: Qianyu Wu briefTitle: The Aim of This Study is to Investigate the Correlation Between the Severity of Glaucoma and Corneal Biomechanics as Well as Anterior Chamber Parameters. overallStatus: ACTIVE_NOT_RECRUITING date: 2022-10-20 date: 2024-12-31 date: 2024-12-31 date: 2024-04-01 date: 2024-04-01 name: Henan Provincial People's Hospital class: OTHER briefSummary: The ocular biomechanical differences between the normal control group and primary glaucoma patients, including those treated with conventional medication, laser therapy, and surgery, were compared. Additionally, an investigation was conducted to explore the relationship between anterior chamber parameters, corneal biomechanics, and the severity of glaucoma conditions: Glaucoma studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 80 type: ESTIMATED name: Observational study measure: IOP measure: bIOP measure: ACD measure: ACW measure: SSI measure: VF sex: ALL minimumAge: 22 Years maximumAge: 79 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Henan Provincial People's Hospital city: Zhengzhou state: Henan zip: 450003 country: China lat: 34.75778 lon: 113.64861 hasResults: False
nctId: NCT06340048 id: XC Liu briefTitle: Epicardial Injection of hiPSC-CMs to Treat Severe Chronic Ischemic Heart Failure overallStatus: RECRUITING date: 2023-09-05 date: 2024-09-05 date: 2025-03-05 date: 2024-04-01 date: 2024-04-01 name: Help Therapeutics class: INDUSTRY name: TEDA International Cardiovascular Hospital briefSummary: The purpose of this clinical study is to evaluate the feasibility, safety and efficacy of intramyocardial injection of human induce pluripotent stem cell-derived cardiomyocytes (HiCM-188) during coronary artery bypass grafting (CABG) surgery in patients with severe chronic ischemic heart failure. conditions: Heart Failure studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: NONE count: 36 type: ESTIMATED name: HiCM-188 therapy measure: The incidence of major Serious Adverse Events (SAE) measure: Grade 4 or above arrhythmias measure: The incidence of tumor measure: Left ventricular geometry as assessed by cardiac magnetic resonance imaging (MRI) measure: Size of myocardial infarction as assessed by MRI measure: Ventricular wall motion as assessed by MRI measure: Left ventricular ejection fraction as assessed by MRI measure: Cardiac Volumes as assessed by MRI measure: Cardiac output (CO) as assessed by MRI measure: 10.End-diastolic myocardial mass as assessed by MRI measure: Left ventricular ejection fraction (LVEF) as assessed by Echocardiography measure: Fractional shortening (FS) as assessed by Echocardiography measure: Left ventricular dimensions as assessed by Echocardiography measure: Cardiac Volumes as assessed by Echocardiography measure: Mitral valve inflow spectrum(E/A) as assessed by Echocardiography measure: Longitudinal strain as assessed by Echocardiography measure: Myocardial viability as assessed by SPECT measure: Myocardial blood flow as assessed by SPECT measure: NT-proBNP Levels measure: 6-minute walking distance measure: New York Heart Association (NYHA) functional classification measure: Changes of Quality of Life (QoL) as assessed by Minnesota Living with Heart Failure Questionnaire (MLHFQ) measure: Changes of Quality of Life(QOL) as assessed by 36-Item Short Form Survey (SF-36) sex: ALL minimumAge: 35 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: TEDA International Cardiovascular Hospital status: RECRUITING city: Tianjin state: Tianjin zip: 300457 country: China name: Xiaocheng Liu role: CONTACT phone: +86-022-65208030 name: Xiaocheng Liu role: PRINCIPAL_INVESTIGATOR lat: 39.14222 lon: 117.17667 hasResults: False
nctId: NCT06340035 id: 20230901 briefTitle: Percutaneous Peripheral Nerve Stimulation of Gluteus Nerves to Improve Hip Strength and Power overallStatus: ACTIVE_NOT_RECRUITING date: 2023-09-01 date: 2024-04 date: 2024-06 date: 2024-04-01 date: 2024-04-01 name: Hospital Clinic of Barcelona class: OTHER briefSummary: The goal of this pilot clinical trial is to evaluate whether the ultrasound-guided percutaneous peripheral nerve stimulation through a needle results in greater gains in strength and power compared to the administration of current through surface electrodes in patients undergoing strength and power assessments. The main questions it aims to answer are:
Researchers will compare the experimental group to the control group to see if the method of current delivery (percutaneous vs. transcutaneous) has a significant impact on the gains in strength and power. This comparison is based on the hypothesis that percutaneous delivery of current, guided by ultrasound, is more effective than simply positioning a surface electrode for transcutaneous stimulation. The evaluation of strength and power will be performed through a linear encoder that measures peak strength and concentric power in each repetition, conducted by a blind operator unaware of the patients' group allocations. conditions: Chronic Pain conditions: Chronic Knee Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: This pilot study utilizes a randomized parallel-group design, focusing on procedure feasibility for future clinical trials, in line with extended CONSORT guidelines for pilot studies. Participants, selected through a convenience sampling method due to their chronic knee pain, received pre- and post-treatment evaluations to assess the effect on gluteal muscle function. Post-informed consent, participants were allocated to either TENS or ultrasound-guided percutaneous nerve stimulation via a computer-generated randomization process executed with GraphPad Software (San Diego, CA, USA), ensuring a balanced 1:1 ratio. primaryPurpose: TREATMENT masking: TRIPLE maskingDescription: In the study, blinding will be implemented to minimize bias. The evaluating clinician will be blinded to participant group assignments, ensuring assessments are unbiased. Similarly, the data analyst will also be blinded, analyzing data without knowledge of group allocations to maintain impartiality. Data will be handled objectively, with statistical methods applied blindly to compare treatment groups. Despite challenges in completely blinding participants due to the distinct nature of interventions, every effort will be made to minimize potential bias. whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 12 type: ACTUAL name: TENS name: Percutaneous Peripheral Nerve Stimulation measure: Hip Extension Concentric Peak Power (Watts) measure: Hip Extension Concentric Peak Strength (Newtons) measure: Concentric Phase Velocity (m/s) measure: Maximum Strength (1RM in kgs) sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Barcelona city: Barcelona zip: 08036 country: Spain lat: 41.38879 lon: 2.15899 hasResults: False
nctId: NCT06340022 id: 2022-31 briefTitle: Pain and Anxiety Levels of Sleeperone Electronic Anesthesia System in Pediatric Patients overallStatus: COMPLETED date: 2023-03-13 date: 2023-10-02 date: 2023-11-15 date: 2024-04-01 date: 2024-04-01 name: Eskisehir Osmangazi University class: OTHER briefSummary: The conventional method used for dental anesthesia in children is the administration of a local anesthetic solution by injection. Although this process successfully eliminates pain during the procedure, it continues to be a problem for many children in terms of dental anxiety before and during anesthesia administration.