hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06276075 id: 10/KRN/2020 briefTitle: The Impact of Erigo®Pro Therapy and Motor Imagery on the Balance of Stroke Patients. overallStatus: COMPLETED date: 2022-12-15 date: 2023-05-10 date: 2023-09-10 date: 2024-02-23 date: 2024-02-23 name: Anna Olczak class: OTHER briefSummary: The aim of the study is to examine the impact of motor imagery, Erigo®Pro tilt table intervention, and classic rehabilitation on the balance of people after a stroke. conditions: Stroke studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 66 type: ACTUAL name: Conventional rehabilitation, the Erigo®Pro table, motor imagery measure: Trunk Control Test measure: Berg Balance Scale measure: RiabloTM device measure: RiabloTM device measure: Luna EMG measure: Luna EMG sex: ALL minimumAge: 38 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Military Institute of Medicine city: Warsaw state: Masovian District zip: 04-141 country: Poland lat: 52.22977 lon: 21.01178 hasResults: False
nctId: NCT06276062 id: Titanium nail usage briefTitle: Uses of Titanium Nail in Pediatric Fractures overallStatus: RECRUITING date: 2023-09-01 date: 2024-09 date: 2024-10 date: 2024-02-23 date: 2024-02-28 name: Sohag University class: OTHER briefSummary: The aim of this study is to investigate the short term functional and radiological outcomes of using double short titanium elastic nails as treatment of pediatric distal radius fractures. conditions: Trauma Injury of Upper Extremity Forearm Multiple conditions: Fracture of Distal End of Radius studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 15 type: ESTIMATED name: Distal radius fracture fixation in pediatrics. measure: Comparison between usage of titanium nail and old methods sex: ALL minimumAge: 4 Years maximumAge: 16 Years stdAges: CHILD facility: Sohag university status: RECRUITING city: Sohag country: Egypt lat: 26.55695 lon: 31.69478 hasResults: False
nctId: NCT06276049 id: DGETRRP2023-54 briefTitle: ChatGPT Helping Advance Training for Medical Students: A Study on Self-Directed Learning Enhancement acronym: CHAT-MS overallStatus: ACTIVE_NOT_RECRUITING date: 2023-11-25 date: 2024-01-06 date: 2024-03-02 date: 2024-02-23 date: 2024-02-23 name: Wang Shalong class: OTHER name: Central South University briefSummary: The goal of this clinical trial is to evaluate the effect of LearnGuide, a custom GPT developed with ChatGPT for supporting self-directed learning (SDL) in medical students. The main questions it aims to answer are:
If there is a comparison group: Researchers will compare the group utilizing LearnGuide for SDL and the group without this tool to see if there is a significant difference in SDL skills, critical thinking, and learning flow experiences. conditions: Self-Directed Learning conditions: Artificial Intelligence conditions: Medical Education studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 103 type: ACTUAL name: custom GPT supported self-directed learning measure: Self-Directed Learning Scale measure: Cornell Critical Thinking Test (CCTT) Level Z measure: Flow Short Scale sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Geriatirc Surgery city: Changsha state: Hunan zip: 410011 country: China lat: 28.19874 lon: 112.97087 hasResults: False
nctId: NCT06276036 id: CAPID briefTitle: Autoimmune Cytopenias as a Sign of Primary Immunodeficiency. overallStatus: ACTIVE_NOT_RECRUITING date: 2019-07-23 date: 2024-12-01 date: 2025-06-01 date: 2024-02-23 date: 2024-03-29 name: Meyer Children's Hospital IRCCS class: OTHER briefSummary: Autoimmune cytopenias resistant to treatment are among the most common clinical manifestations observed in patients with congenital alterations of the immune system, such as primary immunodeficiencies (PI). The exact contribution of immune system alterations to the pathogenesis of autoimmune cytopenias has not yet been fully elucidated. Moreover, conventionally employed therapeutic strategies often fail, leading to increased healthcare costs, high morbidity, and even mortality. Therefore, there is a need to establish clinical guidelines for diagnosis and to identify early biomarkers capable of identifying individuals responsive to therapy. Thus, a systematic approach to the study of such pathologies will allow for the identification of early biomarkers and facilitate the development of targeted therapeutic strategies conditions: Cytopenia studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 53 type: ACTUAL name: Identification of specific markers measure: Identification of specific markers sex: ALL minimumAge: 1 Year maximumAge: 17 Years stdAges: CHILD facility: University of South Florida city: Tampa state: Florida zip: 33620 country: United States lat: 27.94752 lon: -82.45843 facility: Ghent University Hospital city: Ghent country: Belgium lat: 51.05 lon: 3.71667 facility: Clinica Pediatrica - Università di Catania city: Catania country: Italy lat: 37.49223 lon: 15.07041 facility: Meyer Children's Hospital IRCCS city: Florence country: Italy lat: 43.77925 lon: 11.24626 facility: IRCCS Istituto Giannina Gaslini city: Genova country: Italy lat: 44.40478 lon: 8.94438 facility: Azienda Ospedaliero Universitaria Pisana city: Pisa country: Italy lat: 43.70853 lon: 10.4036 hasResults: False
nctId: NCT06276023 id: 2023P003638 id: 1R01AG078204-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R01AG078204-01 briefTitle: Supporting Our Caregivers In ADRD Learning (SOCIAL) acronym: SOCIAL overallStatus: RECRUITING date: 2024-03-22 date: 2025-03-15 date: 2025-04-01 date: 2024-02-23 date: 2024-03-25 name: Massachusetts General Hospital class: OTHER name: National Institute on Aging (NIA) name: University of California, San Francisco briefSummary: Building on limitations of prior research, the investigators developed the Mindful and Self-Compassionate Care Program (MASC) to help caregivers of persons with Alzheimer Disease and Related Dementias (ADRD) manage stress associated with the general caregiver experience including stress stemming from managing challenging patient behaviors. MASC teaches: (1) mindfulness skills; (2) compassion and self-compassion skills; and (3) behavioral management skills. MASC also provides psychoeducation and group-based training and skill practice to facilitate skill uptake and integration within the caregiver experience and tasks.
Relevant stakeholders (caregivers of persons with ADRD) will participate in the intervention. conditions: Alzheimer's Disease and Related Dementias conditions: Quality of Life conditions: Caregiver Stress studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SINGLE_GROUP interventionModelDescription: MASC is an intervention that includes evidence-based skills of: 1) mindfulness; 2) compassion toward others and self; 3) behavioral management skills. MASC comprises 6 sessions delivered in a group format over secure live video with Zoom. Each session includes psychoeducation on program skills, skill practice, strategies to incorporate the skill into the caregiver experience, and strategies for sustained practice. primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: PARTICIPANT count: 80 type: ESTIMATED name: Mindful and Self-Compassionate Care Program (MASC) name: Health Education Program (HEP) measure: Feasibility of Recruitment measure: Feasibility of Randomization measure: Feasibility of Assessment Measures measure: Feasibility of Quantitative Measures measure: Adherence to treatment measure: Patient's Global Impression of Change (PGIC) measure: Perceptions of Questionnaire Battery measure: Adherence to Home Practice measure: Perceptions of Email and Text Reminders measure: Credibility and Expectancy measure: Modified Perception of Global Improvement measure: Satisfaction with the Intervention measure: Therapist Fidelity measure: Symptoms of Depression measure: Mindfulness measure: Perceived Stress Scale measure: Symptoms of Anxiety measure: The Self-Compassion Scale measure: Compassion measure: Caregiver self-efficacy measure: Loneliness measure: Social Support measure: Well-being measure: Distress Due to Patient Challenges Behaviors measure: Dyadic Relationship Scale sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Massachusetts General Hospital status: RECRUITING city: Boston state: Massachusetts zip: 02114-2524 country: United States name: Michelle StPaul, MS role: CONTACT email: mstpaul2@mgh.harvard.edu lat: 42.35843 lon: -71.05977 hasResults: False
nctId: NCT06276010 id: 2023-102 briefTitle: Use of Nafamostat Mesilate for Anticoagulation in Patients With ECMO overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2026-03-01 date: 2026-12-31 date: 2024-02-23 date: 2024-02-26 name: Xiaotong Hou class: OTHER briefSummary: The purpose of this study is to evaluate the effectiveness and safety of nafamostat mesilate compared with unfractionated heparin for anticoagulation in patients with ECMO after cardiac surgery. conditions: Extracorporeal Membrane Oxygenation Complication studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 80 type: ESTIMATED name: nafamostat mesilate name: unfractionated heparin group measure: Incidence of thrombotic complications measure: Incidence of severe bleeding complications measure: Infusion volume of blood products measure: ACT qualified rate measure: Hospitalization mortality measure: The incidence of oxygenator dysfunction measure: Heparin-induced thrombocytopenia measure: Time to reach the target anticoagulant level for the first time sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Beijing Anzhen Hospital city: Beijing state: Beijing zip: 100029 country: China lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06275997 id: GAIN briefTitle: GAIN Project: Gastric Cancer and Artificial Intelligence acronym: GAIN overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-03 date: 2028-03 date: 2024-02-23 date: 2024-02-23 name: Istituto Clinico Humanitas class: OTHER briefSummary: Our GAIN project comprises four core work packages (WPs): WP1. Nation-level randomized controlled trial; WP2. Development of an innovative AI tool; WP3. Novel microsimulation modelling; WP4. Patient inclusion.
The nation-level multi-center tandem randomized controlled trial (WP1) will contribute to a better understanding of how the real-time AI algorithm can reduce miss rate of early gastric cancer and dysplasia during gastroscopy. Moreover, the innovation project will contribute to development of a novel AI tool (WP2) that can stratify the risk of gastric cancer by identifying in vivo precancerous conditions. Furthermore, a microsimulation modelling will allow us to predict how the use of AI can prevent gastric cancer and affect cost and patients' burdens. The assessment of the balance between benefits and harms is quite crucial especially for this type of medical device because the value of innovative tools is sometimes overestimated due to stakeholders' enthusiasm (WP3). Finally, we will take care of patients' perspective throughout the study project by including patient organization in both WP1, 2, and 3 (WP4). conditions: Gastric Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Parallel/Crossover Study Model; Patients will be randomized 1:1:1:1 primaryPurpose: PREVENTION masking: NONE count: 6600 type: ESTIMATED name: Integration of Artificial Intelligence (AI) assistance to screening gastroscopy measure: Miss rate reduction measure: Change number of Detections measure: patient satisfaction sex: ALL minimumAge: 60 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06275984 id: PI23/00288 id: 4R23/440 type: OTHER domain: IDIAP Jordi Gol briefTitle: Effectiveness of Online Training in Cardiopulmonary Resuscitation Maneuvers for a Network of Volunteers. acronym: EFORCP overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-12 date: 2026-12 date: 2024-02-23 date: 2024-04-15 name: Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina class: OTHER name: Hospital Universitari Joan XXIII de Tarragona. briefSummary: Background: Cardiorespiratory arrest (CPA) occurs when there is a cessation of cardiac mechanical activity, typically diagnosed by the absence of consciousness, pulse, and breathing. Actions taken in response to CPA include recognizing the condition and promptly notifying emergency medical services, initiating Cardiopulmonary Resuscitation (CPR) maneuvers, and employing an Automated External Defibrillator (AED). Survival rates are directly influenced by the time elapsed between CPA onset and the initiation of CPR maneuvers, as well as the quality of these interventions
Applicability and Relevance: This proposal advocates for a significant and innovative project, given the dearth of literature on this topic. While there are existing indications and studies on CPR-AED training among specific populations such as students and healthcare professionals, the presented proposal seeks to broaden the scope of training to encompass the general population. conditions: Cardiorespiratory Arrest conditions: Cardiopulmonary Arrest With Successful Resuscitation studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: PREVENTION masking: NONE count: 156 type: ESTIMATED name: online CPR-AED training measure: Difference between pre and post training scores in ad hoc designed scale measure: Percentage of participants that reach or exceed 10 out of 12 on the checklist measure: Odds ratios (with 95% CI) for adjustment variables measure: Scores on the standard satisfaction questionnaire commonly used by the Catalan Health Institute to evaluate training activities sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: IDIAP Jordi Gol city: Barcelona zip: 08007 country: Spain name: Ester Granado_Font, PhD role: CONTACT phone: 977778715 phoneExt: 405 email: egranado.tgn.ics@gencat.cat name: Ester Granado-Font, PhD role: PRINCIPAL_INVESTIGATOR lat: 41.38879 lon: 2.15899 hasResults: False
nctId: NCT06275971 id: KBSMC 2022-07-006 briefTitle: Effectiveness of Continuous Glucose Monitoring System Among Cardiac Surgery Patients overallStatus: RECRUITING date: 2022-11-24 date: 2024-06-30 date: 2024-08-31 date: 2024-02-23 date: 2024-02-23 name: Kangbuk Samsung Hospital class: OTHER name: DexCom, Inc. briefSummary: The aim of this study is to assess the level of glycemic control and the incidence of surgery-related complications in cardiac patients post-surgery when Continuous Glucose Monitoring (CGM) is utilized, as compared to traditional methods of arterial/venous blood sampling and Point-of-Care Testing (POCT) for glucose monitoring. conditions: Cardiac Disease conditions: PreDiabetes conditions: Diabetes Mellitus studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Treatment group: glycemic control using CGM Control group: glycemic control using arterial/venous blood sampling and POCT glucose primaryPurpose: TREATMENT masking: NONE count: 68 type: ESTIMATED name: Dexcom G6 name: SMBG or venous/arterial blood glucose measure: Time within the target range of 100-180 mg/dL measure: Time within the target range of 100-140 mg/dL measure: Time within the target range of 70-180 mg/dL measure: Time to reach <70 mg/dL measure: Time to reach <54 mg/dL measure: Time to reach >180 mg/dL measure: Time to reach >250 mg/dL measure: Standard Deviation (SD) measure: Coefficient of variation (CV) measure: Mean glucose measure: Glucose management indicator (GMI) measure: Number of days of ICU hospitalization measure: Number of days hospitalized after surgery measure: Number of participants with pneumonia occurrence after surgery measure: Number of participants with wound infection occurrence after surgery measure: Number of participants who underwent CRRT implementation after surgery measure: Number of participants with Atrial fibrillation occurrence after surgery measure: Number of participants with symptomatic CVA (ischemic and hemorrhagic) occurrence after surgery measure: Changes in concentration of serum CRP level after surgery measure: Mortality within 30 days of surgery sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Kangbuk Samsung Hospital status: RECRUITING city: Seoul zip: 03181 country: Korea, Republic of name: Sun Joon Moon, MD role: CONTACT lat: 37.566 lon: 126.9784 hasResults: False
nctId: NCT06275958 id: 2023-506115-17 id: 2023-506115-17 type: EUDRACT_NUMBER briefTitle: DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients With Metastatic Colorectal Cancer acronym: DOSAGE overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2028-06 date: 2028-12 date: 2024-02-23 date: 2024-02-23 name: Leiden University Medical Center class: OTHER name: Dutch Colorectal Cancer Group name: Stichting Darmkanker briefSummary: The goal of this phase III, open-label, non-inferiority randomized controlled clinical trial is compare upfront dose-reduced chemotherapy with the standard dose chemotherapy in older patients ( ≥70 years) with metastasized colorectal cancer, with regard to progression-free survival (PFS). The choice between monotherapy (a fluoropyrimidine) and doublet chemotherapy (a fluoropyrimidine with oxaliplatin) will be made for each individual patient based on expected risk of chemotherapy toxicity (according to the G8 screening). Patients classified as low risk of toxicity will be randomized between doublet chemotherapy in either full-dose, or with an upfront dose-reduction of 25%. Patients classified as high risk will be randomized between monotherapy in either full-dose or upfront dose-reduction.
nctId: NCT06275945 id: 1010073 briefTitle: Feasibility Study of A VoRo UrologIc ScaffolD (ARID) acronym: ARID overallStatus: RECRUITING date: 2023-04-03 date: 2026-07-30 date: 2026-10-30 date: 2024-02-23 date: 2024-02-23 name: Levee Medical, Inc. class: INDUSTRY name: RQMplus briefSummary: The objective of this study is to evaluate the safety and performance of the Voro Urologic Scaffold as a prophylactic treatment for post-prostatectomy stress urinary incontinence.
The study is a prospective, multicenter, single arm study. Up to 40 subjects will be treated at up to 3 investigational sites in Panama. Subjects will be followed up post-treatment at catheter removal, 6 weeks post prostatectomy, 3 months, 6 months, 12 months and 2 years. conditions: Stress Urinary Incontinence conditions: Radical Prostatectomy studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Prospective, non-randomized first-in-man study primaryPurpose: PREVENTION masking: NONE count: 40 type: ESTIMATED name: Voro Urologic Scaffold measure: The change in pad weight of 24-hour pad weight test from baseline to post procedure 6-month and 12-month follow-ups. measure: The change in pad weight of 1-hour pad weight test from baseline to post procedure 6-month and 12-month follow-ups. measure: The changes in the standing cough test (SCT) from baseline to post procedure 6-month and 12-month follow-ups. sex: MALE minimumAge: 45 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: National Hospital status: RECRUITING city: Panama City state: Punta Pacifica country: Panama name: Natalia Vega role: CONTACT email: nvega@candmresearch.org name: Margelis Munoz role: CONTACT phone: 507-6499-9304 email: mmunoz@candmresearch.org name: Gustavo Espino, MD role: PRINCIPAL_INVESTIGATOR lat: 8.9936 lon: -79.51973 hasResults: False
nctId: NCT06275932 id: TermoNeo/2023 briefTitle: Management of Healthy Newborn's Body Temperature at Birth overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-04-01 date: 2025-05-31 date: 2024-02-23 date: 2024-02-23 name: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico class: OTHER briefSummary: At birth, the newborn begins a process of adaptation to extrauterine life. One of the phases of this stabilization process is the maintenance of body temperature; indeed, the newborn passes from a warm environment (mother's womb) of around 37°C to an environment with a temperature lower (delivery room) and, therefore, must implement a series of physiological processes to be able to maintain body temperature constant and within ideal ranges through a balance between production and heat loss.
One of the factors that affects heat loss in the delivery room is the relationship between surface area, volume and body mass of the newborn. The decrease in body temperature is directly related to gestational age and weight at birth; indeed, this problem is much more present in premature and/or low weight newborns at birth. Even if a full-term newborn has a more developed thermoregulation center than a preterm newborn, this does not mean that this type of newborns is not at risk heat dispersion.
The aim of this study is to evaluate two healthcare interventions to prevent heat loss of healthy newborns at birth. conditions: Newborn, Infant conditions: Body Temperature conditions: Delivery Room studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 776 type: ESTIMATED name: Interventional group name: Standard of care group measure: Newborn's body temperature at the end of skin-to-skin contact measure: Newborns' proportion with a body temperature < 36.5°C when arriving at the nursery measure: Newborns' proportion with temperature below 36.0°C at the end of skin-to-skin contact and at arrival in the nursery measure: Newborns' proportion with moderate hypothermia (temperature 36.0 - 36.4°C) at the end of skin-to-skin contact and at arrival in the nursery measure: Newborns' proportion with hyperthermia (temperature > 37.5°C) at the end of skin-to-skin contact and at arrival in the nursery measure: Newborns' average temperature one hour after arriving at the nursery measure: Duration of nursery stay measure: Duration of skin-to-skin contact measure: Newborns' proportion exclusively breastfed at discharge measure: Type of breastfeeding at discharge measure: Newborns' proportion with hypoglycemia during hospitalization measure: Newborns' proportion affected by respiratory distress syndrome measure: Newborns' proportion transferred to the Neonatal Intensive Care Unit (NICU) measure: Newborns' weight loss at discharge measure: Mortality before discharge from hospital sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico city: Milan zip: 20122 country: Italy name: Gabriele Sorrentino, pedRN role: CONTACT phone: +393496060149 email: gabriele.sorrentino@policlinico.mi.it name: Gabriele Sorrentino, pedRN role: PRINCIPAL_INVESTIGATOR lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06275919 id: IOV-BT-1-2023 MIRAGE briefTitle: Regorafenib for Recurrent Grade 2 and 3 Meningioma (MIRAGE Trial) acronym: MIRAGE overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-12 date: 2027-03 date: 2024-02-23 date: 2024-03-15 name: Istituto Oncologico Veneto IRCCS class: OTHER name: Bayer briefSummary: The focus of this study will be to investigate whether Regorafenib demonstrates antitumor activity against recurrent grade II or III meningiomas.
Noteworthy, Regorafenib showed antitumor activity in vitro and in vivo in a recent study; indeed, Regorafenib showed significant inhibition of meningioma cell motility and invasion and in vivo, mice with orthotopic meningioma xenografts showed a reduced volume of signal enhancement in MRI following Regorafenib therapy; this translated in a significantly increased overall survival time (p\<0.05) for Regorafenib treated mice.