hackint0sh/New-Dataset huggingface dataset:
* Definition of a standardized recommendation for pre- and postoperative imaging of Moyamoya patients conditions: Moyamoya Disease conditions: Moyamoya studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 50 type: ESTIMATED name: MRI name: H2 15O PET/CT name: Biosampling measure: Value of CO2-triggered BOLD MRI compared to PET/CT measure: Vessel-Wall contrast enhancement measure: Circulating endothelial cells measure: PCR-based virus sampling sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06330805 id: OSU-23069 id: NCI-2024-00705 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) briefTitle: Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate Cancer overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2027-12-31 date: 2027-12-31 date: 2024-03-26 date: 2024-03-26 name: Ohio State University Comprehensive Cancer Center class: OTHER name: Pfizer name: Myovant Sciences GmbH name: Sumitomo Pharmaceuticals America briefSummary: This phase II trial compares the effect of relugolix to leuprolide on cardiac function and performance in patients with prostate cancer. Androgen deprivation therapy (ADT) has been a key component for the treatment of advanced prostate cancer for decades. The term androgen deprivation therapy means lowering a man's testosterone. Long-term studies show that ADT may contribute to a detriment to cardiac health and predisposes men to developing cardiac diseases. Recent studies suggest that men taking relugolix for treatment of prostate cancer may have a lower risk of developing cardiovascular problems, but more studies are needed to understand this observation, and there are currently no studies reporting the direct impact of ADT (relugolix, versus the more-commonly used leuprolide) on cardiac function and outcomes.
3. Provide blood samples at specific intervals during the study period to test for changes in steroid levels and certain biomarkers conditions: Prostate Adenocarcinoma conditions: Stage IIB Prostate Cancer AJCC v8 conditions: Stage IIC Prostate Cancer AJCC v8 studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 70 type: ESTIMATED name: Biospecimen Collection name: Contrast Agent name: Leuprolide name: Magnetic Resonance Imaging name: Physical Performance Testing name: Relugolix measure: Physiologic alterations in cardiopulmonary function - Myocardial perfusion measure: Physiologic alterations in cardiopulmonary function - Maximal rate of oxygen consumption measure: Quality of life using EPIC-26 measure: Quality of life using EORTC QLQ-C30 measure: Quality of life using European (Euro) Qol-5-Dimension 5-level (EQ-5D-5L) measure: Quality of life using PROMIS measure: Functional tests of strength and balance using Timed Up-and-Go measure: Functional tests of strength and balance using 10-meter walk time measure: Functional tests of strength and balance using Grip strength measure: Changes in body composition sex: MALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ohio State University Comprehensive Cancer Center city: Columbus state: Ohio zip: 43210 country: United States name: Shang-Jui Wang role: CONTACT phone: 614-366-9306 email: Shang-Jui.Wang@osumc.edu name: Shang-Jui Wang role: PRINCIPAL_INVESTIGATOR lat: 39.96118 lon: -82.99879 hasResults: False
nctId: NCT06330792 id: mechanical low back pain briefTitle: Effect of Bio-mechanical Awareness and Core Stability Exercises on Mechanical Low Back Pain overallStatus: NOT_YET_RECRUITING date: 2024-05-04 date: 2024-08-01 date: 2024-12-01 date: 2024-03-26 date: 2024-04-25 name: Cairo University class: OTHER briefSummary: investigate the effect of bio-mechanical awareness and core stability exercises on mechanical low back pain among Egyptian Physiotherapists conditions: Mechanical Low Back Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Physiotherapists will be randomly subdivided into two equal groups in number. Group (A) (Experimental Group): This group will receive biomechanical awareness advices while working and core stability exercises.
Group (B) (Control Group): This group will receive core stability exercises only. primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 66 type: ESTIMATED name: bio-mechanical awareness name: core stability exercises measure: intensity of low back pain measure: back muscle endurance measure: level of function (disability) associated with mechanical Low Back Pain measure: Fatigue Severity measure: psycho-social factors at work sex: ALL minimumAge: 25 Years maximumAge: 40 Years stdAges: ADULT hasResults: False
nctId: NCT06330779 id: UWest briefTitle: Trauma-adapted Yoga in Child & Adolescent Psychiatry. acronym: TAY-CAP overallStatus: NOT_YET_RECRUITING date: 2025-01-01 date: 2027-12-31 date: 2028-12-31 date: 2024-03-26 date: 2024-03-26 name: University West, Sweden class: OTHER name: Västra Götalands Region name: Region Stockholm name: Region Skåne name: Region Värmland name: Region Östra Gotland name: Region Örebro briefSummary: The goal of this randomized clinical trial is to evaluate the efficacy of trauma-adapted yoga as a complementary intervention to care as usual in child and adolescents psychiatry clinics, in the population of adolescents with the diagnosis of ADHD and/or PTSD. We hypothesize that trauma-adapted yoga (TAY) is an effective non-pharmacological intervention for adolescent with ADHD and/or PTSD. Aims: (1) Validate the impact of TAY on the mental health \& quality of life of adolescents with ADHD and/or PTSD. (2) Investigate the feasibility of online TAY for continued self-care. (3) Explore adolescents' experiences \& parental perspectives on TAY in their treatment. (4) Explore healthcare professionals' experience on the integration of TAY into clinical practice.
Within and between group (yoga group vs waiting list) analyses will be performed. conditions: ADHD conditions: PTSD conditions: Quality of Life conditions: Self-Control conditions: Pain conditions: Affect studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 180 type: ESTIMATED name: Trauma-adapted yoga measure: Negative experience score CPSS-5-S measure: Inattention, impulsivity score measure: Resilience score measure: Pain frequency and intensity measure: affect measure: Self-directednes measure: Quality of life score sex: ALL minimumAge: 12 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT hasResults: False
nctId: NCT06330766 id: PET24 briefTitle: Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Transcatheter Aortic Valve Implantation Patients acronym: DENTAVI overallStatus: RECRUITING date: 2020-01-01 date: 2026-01-01 date: 2026-01-01 date: 2024-03-26 date: 2024-03-26 name: Odense University Hospital class: OTHER briefSummary: In Odense University Hospital preoperative dental screening (PDS) protocol for patients treated with Transcatheter Aortic Valve Implantation (TAVI) was changed from mandatory to targeted PDS to between June 2023 to october 2023. The investigators will therefore compare the risk of IE before june 2023 and after october 2023. conditions: Transcatheter Aortic Valve Implantation conditions: Dental conditions: Endocarditis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 1000 type: ESTIMATED name: No preoperative dental screening measure: Number of Participants with Infectious Endocarditis measure: Number of Participants undergoing Oral surgical procedure at dental screening measure: Number of Participants undergoing Tooth extraction at dental screening measure: The different Bacteria types causing the infectious endocarditis assessed by blood culture measure: Number patients with Bacteremia assessed by positive blood culture measure: Number of Participants with IE caused by bacteria from oral foci measure: Number of Participants with Cardiac implantable electronic device risk of IE sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Odense University Hospital, Cardiology Department status: RECRUITING city: Odense zip: 5000 country: Denmark name: Jordi S Dahl, MD,PhD,DMSc role: CONTACT phone: 004524638899 email: Jordi.Sanchez.Dahl@rsyd.dk name: Lytfi Krasniqi, MD role: CONTACT phone: 004524638899 email: Lytfi.Krasniqi@rsyd.dk name: Jordi S Dahl, MD,PhD,DMSc role: PRINCIPAL_INVESTIGATOR name: Lytfi Krasniqi, MD role: PRINCIPAL_INVESTIGATOR lat: 55.39594 lon: 10.38831 hasResults: False
nctId: NCT06330753 id: 2024P000682 briefTitle: Synergy Between Patient and Clinician: Using a Trauma-Informed Care Plan acronym: TICP overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2025-05-15 date: 2025-11-30 date: 2024-03-26 date: 2024-03-26 name: Brigham and Women's Hospital class: OTHER briefSummary: The goal of this prospective study is to test the: acceptability of trauma-informed care plans; the intervention appropriateness; and the feasibility of the trauma-informed care plans in the electronic health care record. Patient seen in various health care settings and how have complex health care needs will be invited to participate in this study. The aims to are:
Aim 1: Explore the acceptability of trauma-informed care plans, the appropriateness of trauma-informed care plans, and the feasibility of Trauma-Informed Care Plans(TICP) when used by clinicians on the health care team (HCTC). Hypothesis 1: HCTC using the TICP will report its acceptability, feasibility, satisfaction and ease of use. Hypothesis 2: HCTC will report heightened awareness of intersection of trauma and social determinants of health. Hypothesis 3: HCTC will report more awareness of the patient's unique preferences and will be better informed regarding the unique plan of care for their patient.
Aim 2: Explore the impact of having a TICP by patients understanding how the TICP may have improved their experience around care and treatment. Hypothesis 1: patients will report: improved satisfaction with their care. Hypothesis 2: patients will report feeling better known by HCT. Hypothesis 3: will report less stress and anxiety related to health care encounters. conditions: Trauma and Stressor Related Disorders conditions: Violence, Structural conditions: Violence, Domestic conditions: Violence, Sexual studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: This is a prospective study designed to explore the acceptability, intervention appropriateness of trauma-informed care plans and the feasibility of trauma-informed care plans by patients and members of the health care team primaryPurpose: TREATMENT masking: NONE maskingDescription: Participants (patients and providers) will be de-identified count: 200 type: ESTIMATED name: Trauma-informed Care Plan- measure: Acceptability of Trauma Informed Care Plans measure: Intervention Appropriateness of Trauma-Informed Care plans measure: Feasibility of the trauma-informed care plans sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT hasResults: False
nctId: NCT06330740 id: AAAU3416 briefTitle: Evaluations of CDS Systems overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-09 date: 2025-12 date: 2024-03-26 date: 2024-03-26 name: New York Presbyterian Hospital class: OTHER briefSummary: Indications-based prescribing is a medication ordering system in which a clinician selects an indication, and then the electronic health record (EHR) suggests an appropriate medication regimen. This approach was shown to significantly decrease medication ordering errors in a prototype environment. However, the effect of indications-based prescribing on preventing ordering errors has not been rigorously evaluated in a real-world healthcare setting. Antibiotics are the medication class most likely to contain ordering errors, which can lead to significant patient harm. At NewYork-Presbyterian (NYP) a robust antimicrobial indication-based order set was developed to help clinicians identify the appropriate antibiotic, dose, frequency, and duration, based on type of infection and patient-specific characteristics, but it is not widely used. The investigators propose a randomized controlled trial to assess the effectiveness of this indications-based order set for reducing antimicrobial ordering errors. conditions: Safety Issues studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 2000 type: ESTIMATED name: Clinical Decision Support measure: The combined rate of Wrong Drug, Wrong Duration, Wrong Dose and Wrong Frequency Retract-And-Reorder (RAR) events will be combined to create an overall rate of near-miss ordering errors in the control and intervention arm. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06330714 id: AV.RMH.v01-01 briefTitle: Remote Monitoring of Chronic Illness Patients With a IHAP Home Wireless Hub and Vitals Measurements acronym: REMOTE-HUB-1 overallStatus: COMPLETED date: 2018-07-01 date: 2018-11-30 date: 2018-12-30 date: 2024-03-26 date: 2024-03-26 name: Aventyn, Inc. class: INDUSTRY name: Intel Corporation briefSummary: This is planned as a feasibility study.
The second objective is assessing patient response to use of mobile device monitoring and patient self-monitoring skills to transmit vital signs data using the IHAP wireless home hub device conditions: Chronic Disease of Cardiovascular System studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 10 type: ACTUAL name: Symptoms of chronic illness. measure: Mobile Home Device Hub Data Resiliency measure: Patient Self Monitoring sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Institute for Liver Health city: Chandler state: Arizona zip: 85248 country: United States lat: 33.30616 lon: -111.84125 hasResults: False
nctId: NCT06330701 id: 2023URO0001 briefTitle: Stone Access and Removal (STAR) Study acronym: STAR overallStatus: RECRUITING date: 2024-01-18 date: 2024-12-31 date: 2025-03-31 date: 2024-03-26 date: 2024-04-25 name: Auris Health, Inc. class: INDUSTRY briefSummary: The purpose of the study is to assess procedural completion, the post-operative stone clearance and the safety profile following robotic mini-Percutaneous Nephrolithotomy (PCNL) performed with the MONARCH Platform, Urology. conditions: Kidney Calculi studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 60 type: ESTIMATED name: Robotic-assisted mini-PCNL measure: Percentage of Robotic-assisted mini-Percutaneous Nephrolithotomy (PCNL) Kidney Stone Removal Procedure Completed measure: Stone Free Rate (%) measure: Number of Adverse Events measure: Number of Procedure Conversions to Conventional Treatment Methods due to study device-related safety event sex: ALL minimumAge: 22 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Indiana University status: RECRUITING city: Bloomington state: Indiana zip: 47401 country: United States lat: 39.16533 lon: -86.52639 facility: UW School of Medicine and Public Health status: RECRUITING city: Madison state: Wisconsin zip: 53705 country: United States lat: 43.07305 lon: -89.40123 hasResults: False
nctId: NCT06330688 id: ΕΒΔ 53/25.01.2024 briefTitle: Prospective Evaluation of Ultrasound-guided Percutaneous Cholecystostomy With the Trocar Technique overallStatus: RECRUITING date: 2024-03 date: 2026-03 date: 2026-06 date: 2024-03-26 date: 2024-03-26 name: Attikon Hospital class: OTHER briefSummary: The purpose of this study is to further evaluate and investigate the safety and efficacy of ultrasound (US)-guided percutaneous cholecystostomy (PC) with the trocar technique by the patient's bedside. conditions: Cholecystitis, Acute conditions: Cholecystitis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED name: percutaneous cholecystostomy measure: Technical success measure: Procedure-related complications measure: duration of the procedure measure: intraprocedural and post-procedural pain measure: clinical success sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Attikon University Hospital status: RECRUITING city: Chaïdári state: Athens zip: 12461 country: Greece name: Stavros Spiliopoulos, MD, Associate Professor role: CONTACT phone: +302105831812 email: stavspiliop@gmail.com lat: 38.01135 lon: 23.66597 hasResults: False
nctId: NCT06330675 id: 2022-01820 briefTitle: Correct Mobilization Time After CIED Implantation: A Single-centre, Open-label, Non-inferiority RCT overallStatus: RECRUITING date: 2023-02-01 date: 2027-02-01 date: 2027-06-01 date: 2024-03-26 date: 2024-03-26 name: Caporali Elena class: OTHER name: Cardiocentro Ticino briefSummary: Bedrest is usually prescribed for patients management after cardiac electronic device implantation (CIED) in order to prevent complication. Due to the lack of guidelines available on the timing of postoperative mobilization management, the aim of the study is to evaluate the safety of early mobilization, comparing mobilization at 4-h against day-after procedure. conditions: Pacemaker conditions: Defibrillators, Implantable studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 558 type: ESTIMATED name: Early mobilization name: Standard of care measure: Composite endpoint: pacing lead dislodgement, pocket hematoma, pneumothorax, and pericardial effusion measure: Post-operative pain measure: Sleep disturbance measure: Postoperative urinary retention measure: Delirium measure: Orthostatic intolerance measure: Quality of recovery measure: Pressure ulcer measure: Incidence of pacing lead dislodgement, pocket hematoma, pneumothorax, pericardial effusion, and pocket infection sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Cardiocentro Ticino Institute - EOC status: RECRUITING city: Lugano zip: 6900 country: Switzerland name: Elena Caporali, MD role: CONTACT lat: 46.01008 lon: 8.96004 hasResults: False
nctId: NCT06330649 id: 2024-0095 briefTitle: The Acute Effect of and Energy Drink vs. Water Consumption on MAP, HR, and Energy Metabolism overallStatus: RECRUITING date: 2024-01-01 date: 2024-12-31 date: 2025-08-31 date: 2024-03-26 date: 2024-03-26 name: The University of Texas at Arlington class: OTHER briefSummary: The objective of this protocol is to investigate the effect of consumption of a commercially available energy drink beverage on blood pressure, heart rate, and energy metabolism conditions: Cardiovascular Diseases conditions: Hypertension conditions: Diet studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Individuals will be randomly assigned to either an experimental or a control condition. primaryPurpose: PREVENTION masking: SINGLE whoMasked: INVESTIGATOR count: 50 type: ESTIMATED name: Energy Drink name: Water Control measure: Peripheral blood pressure in millimeters of mercury measure: Oxygen consumption milliliters per kilogram of body weight per minute measure: Heart rate in beats per minute sex: ALL minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT facility: UT Arlington - Science and Engineering Innovation and Research Building status: RECRUITING city: Arlington state: Texas zip: 76019 country: United States name: Robert M Brothers, PhD role: CONTACT phone: 817-272-3288 email: matthew.brothers@uta.edu name: Alison Mancera, BS role: CONTACT phone: 8172723288 email: alison.mancera@mavs.uta.edu lat: 32.73569 lon: -97.10807 hasResults: False
nctId: NCT06330636 id: 336-0723 briefTitle: The Acute Effect of D-allulose Consumption on Postprandial Glycaemia overallStatus: ACTIVE_NOT_RECRUITING date: 2023-09-11 date: 2024-03-28 date: 2024-07-31 date: 2024-03-26 date: 2024-04-09 name: University of Nottingham class: OTHER briefSummary: The rare sugar D-Allulose, when consumed in a drink before eating has been shown to reduce the blood glucose response to high carbohydrate drinks or meals in people who are healthy, or have elevated fasting blood glucose concentration. However, the effectiveness of D-allulose to suppress blood glucose concentration when added into carbohydrate containing food products has not been previously reported and as the potential use of allulose is as a sucrose replacer in foods, rather than drinks, it is important that effects and efficacy are tested in this format. The study aimed to extend understanding of the acute effects of D-allulose consumption in humans by testing whether post-eating blood glucose concentration can be modified by the presence of D-allulose in a high carbohydrate breakfast and collecting data on any adverse gastrointestinal effects of consuming D-allulose. conditions: Sugar; Blood, High studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Randomised, placebo controlled cross over design primaryPurpose: BASIC_SCIENCE masking: TRIPLE maskingDescription: Allocation coded A and B, with independent researcher determining allocation and making up the test breakfasts for the study team. whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 12 type: ACTUAL name: D-Allulose name: Sodium Saccharin measure: Incremental area under the curve (iAUC) 180 Glucose Test measure: iAUC 180 Glucose Placebo measure: Glycaemia Test measure: Glycaemia Placebo measure: Insulinemia Test measure: Insulinemia Placebo measure: iAUC 180 Insulin Test measure: iAUC 180 Insulin Placebo measure: iCAS Test measure: iCAS Placebo measure: abdominal discomfort test measure: abdominal discomfort placebo measure: Dietary Fibre measure: Carbohydrate % measure: Fat % measure: Protein % measure: Sugars % sex: ALL minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: David Greenfield Human Physiology Laboratories city: Nottingham state: Notts zip: NG72UH country: United Kingdom lat: 52.9536 lon: -1.15047 hasResults: False
nctId: NCT06330623 id: 0929 id: 321895 type: OTHER domain: HRA briefTitle: Developing Personalised Relative Physical Activity Thresholds in COPD. acronym: IMPACT overallStatus: RECRUITING date: 2023-11-22 date: 2025-03-30 date: 2025-09-01 date: 2024-03-26 date: 2024-03-26 name: University of Leicester class: OTHER briefSummary: The aim of this observational study is to translate the principle of individualised exercise prescription into the evaluation of daily absolute and relative intensity physical activity.