Participants will be randomized in a 1:1 ratio to receive OsrHSA or HpHSA (20g IV qd) for up to 14 days, following an EOT visit. Follow-up visits will be taken on EOT+7d, EOT+14d, and EOT+30d, respectively. conditions: Hypoalbuminemia conditions: Hepatic Cirrhosis studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 328 type: ACTUAL name: OsrHSA name: Plasbumin®-20 measure: To evaluate the efficacy of OsrHSA on elevating the serum albumin level. measure: To estimate the time to reach 35 g/L or more in serum albumin measure: To estimate the change from baseline in serum albumin measure: To estimate the change from baseline in colloid osmotic pressure measure: To estimate the change from baseline in body weight measure: To estimate the change from baseline in abdominal circumference, and ascites severity measure: To estimate the change from baseline in ascites severity sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Beijing Friendship Hospital, Capital Medical University city: Beijing state: Beijing country: China lat: 39.9075 lon: 116.39723 facility: Beijing Youan Hospital, Capital Medical University city: Beijing state: Beijing country: China lat: 39.9075 lon: 116.39723 facility: Chongqing University Three Gorges Hospital city: Chongqing state: Chongqing country: China lat: 29.56278 lon: 106.55278 facility: The Second Affiliated Hospital of Chongqing Medical University city: Chongqing state: Chongqing country: China lat: 29.56278 lon: 106.55278 facility: Mengchao Hepatobiliary Hospital of Fujian Medical University city: Fuzhou state: Fujian country: China lat: 26.06139 lon: 119.30611 facility: The First Affiliated Hospital of Fujian Medical University city: Fuzhou state: Fujian country: China lat: 26.06139 lon: 119.30611 facility: Nanfang Hospital city: Guangzhou state: Guangdong country: China lat: 23.11667 lon: 113.25 facility: The Third Affiliated Hospital, Sun Yat-Sen University city: Guangzhou state: Guangdong country: China lat: 23.11667 lon: 113.25 facility: Huizhou Central People's Hospital city: Huizhou state: Guangdong country: China lat: 23.11147 lon: 114.41523 facility: Affiliated Hospital of Guilin Medical University city: Guilin state: Guangxi country: China lat: 25.28194 lon: 110.28639 facility: Liuzhou Worker's Hospital city: Liuzhou state: Guangxi country: China facility: The First Affiliated Hospital of Guangxi Medical University city: Nanning state: Guangxi country: China lat: 22.81667 lon: 108.31667 facility: Affiliated Hospital Of Zunyi Medical University city: Zunyi state: Guizhou country: China lat: 27.68667 lon: 106.90722 facility: The Fourth Affiliated Hospital, Harbin Medical University city: Harbin state: Heilongjiang country: China lat: 45.75 lon: 126.65 facility: Luoyang Central Hospital city: Luoyang state: Henan country: China lat: 34.68361 lon: 112.45361 facility: The First Affiliated Hospital of Zhengzhou University city: Zhengzhou state: Henan country: China lat: 34.75778 lon: 113.64861 facility: The Sixth People's Hospital of Zhengzhou city: Zhengzhou state: Henan country: China lat: 34.75778 lon: 113.64861 facility: Jingzhou Central Hospital city: Jingzhou state: Hubei country: China lat: 30.35028 lon: 112.19028 facility: TaiHe Hospital city: Shiyan state: Hubei country: China lat: 32.6475 lon: 110.77806 facility: The Central Hospital of Wuhan city: Wuhan state: Hubei country: China lat: 30.58333 lon: 114.26667 facility: Wuhan Jinyintan Hospital city: Wuhan state: Hubei country: China lat: 30.58333 lon: 114.26667 facility: Yichang Central People's Hospital city: Yichang state: Hubei country: China lat: 30.71444 lon: 111.28472 facility: Yueyang Central Hospital city: Yueyang state: Hunan country: China lat: 29.37455 lon: 113.09481 facility: The Third People's Hospital of Zhenjiang city: Zhenjiang state: Jiangsu country: China lat: 32.21086 lon: 119.45508 facility: First Affiliated Hospital of Gannan Medical University city: Ganzhou state: Jiangxi country: China facility: The First Affiliated Hospital of Nanchang University city: Nanchang state: Jiangxi country: China lat: 28.68396 lon: 115.85306 facility: Pingxiang People's Hospital city: Pingxiang state: Jiangxi country: China lat: 27.61672 lon: 113.85353 facility: Yichun People's Hospital city: Yichun state: Jiangxi country: China lat: 47.72143 lon: 128.87529 facility: Hepatobiliary Hospital Of Jilin city: Chang chun state: Jilin country: China lat: 42.74694 lon: 126.24667 facility: The First Hospital of Jilin University city: Chang chun state: Jilin country: China lat: 42.74694 lon: 126.24667 facility: The Sixth People's Hospital of Shenyang city: Shenyang state: Liaoning country: China lat: 41.79222 lon: 123.43278 facility: The People's Hospital of Qinghai city: Xining state: Qinghai country: China lat: 36.62554 lon: 101.75739 facility: Shandong Public Health Clinical Center city: Jinan state: Shandong country: China lat: 36.66833 lon: 116.99722 facility: West China Hospital, Sichuan University city: Chengdu state: Sichuan country: China lat: 30.66667 lon: 104.06667 facility: The Second Affiliated Hospital of Kunming Medical University city: Kunming state: Yunnan country: China lat: 25.03889 lon: 102.71833 facility: Ruian People's Hospital city: Rui'an state: Zhejiang country: China facility: The First School of Medicine, School of Information and Engineering, The First Affiliated Hospital of Wenzhou Medical University city: Wenzhou state: Zhejiang country: China lat: 27.99942 lon: 120.66682 hasResults: False