hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06290362 id: EgeTrial4 briefTitle: Exploring Digitalized Interventions for Stress and Problem Solving overallStatus: COMPLETED date: 2021-04-16 date: 2021-07-30 date: 2021-11-28 date: 2024-03-04 date: 2024-03-07 name: Ege University class: OTHER briefSummary: Excessive and prolonged stress can have detrimental effects on both psychological and physiological health, compromising overall well-being and functioning. This study examines the impact of telepsychiatric group consultation using Instagram as an unexplored online social media platform on stress levels and problem-solving skills among young adults. conditions: Stress conditions: Problem-solving studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: FACTORIAL interventionModelDescription: The current 8-week randomized, single-blind factorial trial was conducted with a control group and one intervention group. Over eight weeks, participants received cognitive behavioral-based intervention through online sessions. Pre-/post-test and follow-up assessments employed. primaryPurpose: PREVENTION masking: SINGLE whoMasked: PARTICIPANT count: 54 type: ACTUAL name: Cognitive Behavioural Theory-based group consultation measure: Perceived Stress Scale (first evaluation with posttest) measure: Problem Solving Inventory (first evaluation with posttest) measure: Perceived Stress Scale (second evaluation with follow up) measure: Problem Solving Inventory (second evaluation with follow up) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ege University city: İzmir zip: 35100 country: Turkey lat: 38.41273 lon: 27.13838 hasResults: False
nctId: NCT06290349 id: DA5221_DM_III briefTitle: Efficacy and Safety of DA5221-T When Added to Ongoing DA5221-B1 and DA5221-B2 Combination Therapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control overallStatus: NOT_YET_RECRUITING date: 2024-02-28 date: 2025-05-31 date: 2025-11-30 date: 2024-03-04 date: 2024-03-04 name: Dong-A ST Co., Ltd. class: INDUSTRY briefSummary: This study evaluates the efficacy and safety of adding the SGLT-2 inhibitor DA5221-T to the combination therapy of DA5221-B1 and the DPP-4 inhibitor DA5221-B2 in patients with type 2 diabetes who have inadequate blood glucose control. The study focuses on assessing the effectiveness and safety of the triple combination therapy. conditions: Type 2 Diabetes studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 162 type: ESTIMATED name: DA5221-T1 name: DA5221-T2 name: Placebo name: DA5221-B1 name: DA5221-B2 measure: Change from the baseline in HbA1c (%) after 24 weeks measure: Change from the baseline in fasting plasma glucose(mg/dL) after 24 weeks measure: Change from the baseline in HbA1c response rate(<7.0%, <6.5%) after 24 weeks measure: Change from the baseline in weight after 24 weeks sex: ALL minimumAge: 19 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Severance Hospital, Yonsei University college of Medicine city: Seoul country: Korea, Republic of name: Cha Bong Soo, Ph.D role: CONTACT email: BSCHA@yuhs.ac lat: 37.566 lon: 126.9784 hasResults: False
nctId: NCT06290336 id: PROTEKT briefTitle: Pre-Operative Exercise Therapy and Patient Education Before Total Knee Replacement acronym: PROTEKT overallStatus: RECRUITING date: 2023-12-20 date: 2025-12-30 date: 2026-12-30 date: 2024-03-04 date: 2024-03-04 name: Linkoeping University class: OTHER_GOV name: Region Östergötland name: Region Jönköping County briefSummary: The goal of this multi-center randomized controlled trial is to investigate the effect of pre-operative exercise therapy and education for patients awaiting knee replacement surgery on subjective knee function, patient satisfaction and enablement compared to standard care.
Participants will be randomized stratified by age (≤ 67 years, \> 67 years) to either pre-operative supervised individualized exercise therapy combined with education two sessions/week (intervention group) or to standard care (control group). The intervention will be continuously ongoing for at least eight weeks from the point of decision for surgery until as close to the surgery as possible. conditions: Knee Osteoarthritis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Multi-center randomized controlled trial primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Outcome assessor blinded to group allocation whoMasked: OUTCOMES_ASSESSOR count: 110 type: ESTIMATED name: Pre-operative exercise therapy and education name: Standardized pre-operative information session measure: Change in Forgotten Joint Score-12 (FJS-12) from baseline to 1 year after surgery measure: Patient satisfaction at 1 year after surgery measure: Change in modified Patient Enablement Instrument-2 (Mod-PEI-2) from baseline to 6 weeks after surgery measure: Change in maximal isometric knee extension in 90 degrees of flexion from baseline to 6 weeks after surgery measure: Change in active knee range of motion from baseline to 6 weeks after surgery measure: Change in 30 seconds Chair to Stand-Test (30sCST) from baseline to 6 weeks after surgery measure: Change in maximal isometric knee extension in 90 degrees of flexion from baseline to 8 weeks after start of intervention and 1-2 weeks before surgery measure: Change in active knee range of motion from baseline to 8 weeks after start of intervention and 1-2 weeks before surgery measure: Change in 30sCST from baseline to 8 weeks after start of intervention and 1-2 weeks before surgery measure: Change in Knee Osteoarthritis Outcome Score (KOOS) from baseline to 8 weeks after start of intervention, 1-2 weeks before surgery, 6 weeks, 3 months and 1 year after surgery measure: : Change in EuroQol 5 Dimensions 3 Levels (EQ5D-3L) from baseline to 8 weeks after start of intervention, 1-2 weeks before surgery, 6 weeks, 3 months and 1 year after surgery measure: Change in International Physical Activity Questionnaire - short form (IPAQ-sf) from baseline to 8 weeks after start of intervention, 1-2 weeks before surgery, 6 weeks, 3 months and 1 year after surgery measure: Change in Mod-PEI-2 from baseline to 8 weeks after start of intervention, 1-2 weeks before surgery, 6 weeks, 3 months and 1 year after surgery measure: Change in FJS-12 from baseline to 8 weeks after start of intervention, 1-2 weeks before surgery and 6 weeks and 3 months after surgery sex: ALL minimumAge: 40 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Linkoping University status: RECRUITING city: Linkoping state: Ostergotland zip: 58183 country: Sweden name: Joanna Kvist, Professor role: CONTACT phone: +46 (0) 13 284664 email: joanna.kvist@liu.se name: Joanna Kvist, Professor role: PRINCIPAL_INVESTIGATOR lat: 58.41086 lon: 15.62157 hasResults: False
nctId: NCT06290323 id: 11/05/2022-9/VIII briefTitle: Effects of Quadratus Lumborum Block on Lower Urinary System Symptoms overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-25 date: 2024-05-15 date: 2024-05-30 date: 2024-03-04 date: 2024-03-04 name: Muğla Sıtkı Koçman University class: OTHER briefSummary: The most common reason for applying to a hospital in the postoperative period due to the double J stent inserted during operations of the uteroscopic lithotripsy is reflected pain (T11-L2). The posterior approximation QL block (QL-P) is known to extend more easily to the thoracic paravertebral cavity or thoracolumbar plane, creating analgesia from T 7' to L 1'. The effects of double J catheter in patients are followed by 'Ureteral Stent Symptom Scoring Survey'. QL-P for postoperative analgesia after URS operations Our primary hypothesis in this prospective, randomized, controlled study is that the symptoms of the sub-urinary system associated with the DJS of the QL-P block will decrease. Our secondary hypotheses in the study are to investigate the effects of the unilateral QL-P block, made under ultrasound guidance, on pain scores that occur after ureteroscopic lithotripsy operations due to unilateral ureteral stones made under spinal anesthesia. conditions: Lower Urinary Tract Symptoms studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Patients with double J catheter inserted into ureteroscopic lithotripsy surgeries due to urethral stones primaryPurpose: PREVENTION masking: SINGLE maskingDescription: The researcher evaluating the survey does not know which group the patients are. whoMasked: OUTCOMES_ASSESSOR count: 154 type: ESTIMATED name: Quadratus lumborum block name: Placebo measure: Quadratus posterior block measure: Pain Score sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mugla Sitki Kocman Training and Research Hospital city: Mugla zip: 48000 country: Turkey lat: 37.21807 lon: 28.3665 hasResults: False
nctId: NCT06290310 id: PAVELA briefTitle: Assessment of Patient-ventilator Asynchrony by Electric Impedance Tomography acronym: PAVELA overallStatus: NOT_YET_RECRUITING date: 2024-04-12 date: 2024-09-01 date: 2024-09-01 date: 2024-03-04 date: 2024-03-04 name: Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged class: OTHER_GOV name: Hochschule Furtwangen University name: Budapest University of Technology and Economics name: Szeged University briefSummary: Patient-ventilator asynchrony (PVA) has deleterious effects on the lungs. PVA can lead to acute lung injury and worsening hypoxemia through biotrauma. Little is known about how PVA affects lung aeration estimated by electric impedance tomography (EIT). Artificial intelligence can promote the detection of PVA and with its help, EIT measurements can be correlated to asynchrony. conditions: Acute Lung Injury studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 10 type: ESTIMATED name: EIT name: patient-ventilator asynchrony assessment measure: distribution measure: connecting asysnchrony cycles with electric impedance tomography measurements measure: identifying unic electric impedance tomography signs of asynchrony sex: ALL minimumAge: 18 Years maximumAge: 100 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Kiskunhalas Semmelweis Hopsital the Teaching Hospital of the University of Szeged city: Kiskunhalas zip: 6400 country: Hungary name: András Lovas, M.D. Ph.D. role: CONTACT phone: 003677522000 phoneExt: 2045 email: landras@halasi-korhaz.hu lat: 46.43402 lon: 19.48479 hasResults: False
nctId: NCT06290284 id: 6322 briefTitle: Comparison Between Mini-midline and the Peripheral Intravenous Catheter acronym: INSERT/2022 overallStatus: COMPLETED date: 2023-09-25 date: 2023-11-17 date: 2023-12-28 date: 2024-03-04 date: 2024-03-04 name: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico class: OTHER briefSummary: The goal of this randomized controlled trial is to investigate the difference between LPC (mini-midline) and PIVC (peripheral venous catheter) on the need of further venipuncture for blood withdrawal or placement of a new vascular access.
Researchers will compare the proportion of patients with repeated venipunctures between LPC and PIVC arms. conditions: Vascular Access Devices conditions: Venous Puncture studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE maskingDescription: The statistician will be provided an anonymized dataset. whoMasked: OUTCOMES_ASSESSOR count: 294 type: ACTUAL name: Long Peripheral Catheter name: Peripheral Intra-Venous Catheter measure: Difference in proportion measure: Adverse events associated with use of LPC and PIVC sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico city: Milan zip: 20122 country: Italy lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06290258 id: 202202143A0 briefTitle: Fecal Microbiota Transplantation for Patients With Autism Spectrum Disorder. overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-07-31 date: 2024-07-31 date: 2024-03-04 date: 2024-03-04 name: Chang Gung Memorial Hospital class: OTHER briefSummary: This study aims to evaluate the efficacy of fecal microbiota transplantation on the gastrointestinal symptoms, autistic symptoms and emotional behavior symptoms of patients with autism spectrum disorder, and investigate the relations between the brain-gut axis, cytokines and autism spectrum disorder. Fecal microbiota transplantation have the potentials to improve intestinal microbiota composition, regulate immunity, and then improve gastrointestinal symptoms, autistic symptoms, emotional behavior symptoms and sleep of children with autism spectrum disorder. Early intervention at school-age may even benefit development, improve cognition and prognosis. conditions: Autism Spectrum Disorder conditions: Gastrointestinal Diseases conditions: Healthy studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 60 type: ESTIMATED name: Fecal microbiota transplantation measure: Changes of gastrointestinal symptoms of patients with ASD after FMT measure: Changes of autistic symptoms of patients with ASD after FMT measure: Changes of the diversity of intestinal microbiota of patients with ASD after FMT measure: Changes of cytokine levels of patients with ASD after FMT measure: Changes of repetitive behavior symptoms of patients with ASD after FMT measure: Changes of autistic behavior symptoms of patients with ASD after FMT measure: Changes of emotion and behavior symptoms of patients with ASD after FMT measure: Changes of inattention and hyperactivity of patients with ASD after FMT measure: Changes of quality of life of patients with ASD after FMT measure: Changes of objective sleep of patients with ASD after FMT by actigraphy recording measure: Changes of subjective sleep of patients with ASD after FMT measure: Changes of intelligence of patients with ASD after FMT measure: Changes of attention and impulse control of patients with ASD after FMT sex: ALL minimumAge: 7 Years maximumAge: 30 Years stdAges: CHILD stdAges: ADULT facility: Wei-Chih Chin city: Taoyuan city zip: 333423 country: Taiwan name: Wei-Chih Chin role: CONTACT phone: +886 3 3281200 phoneExt: 3836 email: auaug0327@cgmh.org.tw lat: 24.95233 lon: 121.20193 hasResults: False
nctId: NCT06290245 id: P.T.REC/012/005045 briefTitle: PEP Buddy Impact on Breathing, Exercise, and Sleep Quality in COPD Patients overallStatus: RECRUITING date: 2024-03 date: 2024-10 date: 2024-12 date: 2024-03-04 date: 2024-03-04 name: Cairo University class: OTHER briefSummary: Exercise intolerance and sleeping problems are among the most common symptoms experienced by patients with chronic obstructive pulmonary disease (COPD), which is associated with lung dynamic hyperinflation (DH). There was evidence that positive expiratory pressure (PEP), which less costly devices could offer, could reduce DH.
PEP buddy is an adjunct to current COPD therapies, such as inhalers and pulmonary rehabilitation. It provides a tool for self-management and breathing re-training, reducing dyspnea and improving quality of life. conditions: Pulmonary Disease, Chronic Obstructive studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 90 type: ESTIMATED name: PEP Buddy name: aerobic exercise measure: dyspnea measure: pulmonary function measure: exercise capacity measure: Sleep quality measure: Health-related quality of life (HRQoL) sex: ALL minimumAge: 55 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Faculty of Physical Therapy status: RECRUITING city: Giza state: Dokki zip: 11432 country: Egypt name: Ebtesam N Nagy role: CONTACT phone: +201278141946 email: Dr.EbtesamNagy2@outlook.com lat: 30.00808 lon: 31.21093 hasResults: False
nctId: NCT06290232 id: IRB-P00044498 briefTitle: Fetoscopic Laser Photocoagulation in Management of Vasa Previa acronym: FLUMEN overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-05-01 date: 2027-12-31 date: 2024-03-04 date: 2024-03-12 name: Boston Children's Hospital class: OTHER briefSummary: In this research study, the investigators want to learn more about the safety and effectiveness of a fetal surgery, known as fetoscopic laser photocoagulation (FLP), for the treatment of a pregnancy condition called vasa previa (VP). Vasa previa is a pregnancy complication that happens when blood vessels from the fetus grow over the entrance to the womb. In a VP pregnancy, natural vaginal birth is deadly for the baby in more than half of cases due to the bursting of VP vessels and severe blood loss. Currently, VP patients are recommended to be closely monitored and often hospitalized once they reach the third trimester of pregnancy. An early delivery by C-section would typically be performed in order to avoid breaking the exposed fetal vessels.
Fetoscopic laser photocoagulation is a minimally invasive surgery in the womb to remove or correct abnormal blood vessels and tissues. In the FLP procedure, the surgeon uses a fetoscope (a tiny telescope) and a laser device to seal off unprotected vessels. While this surgery has been used to treat other pregnancy conditions, it has not yet been proven to be safe and/or effective for the treatment of vasa previa. This treatment aims to eliminate the VP, and, if successful, may have the potential to minimize the risk of bleeding, thereby enabling patients to avoid long hospitalization before delivery. This procedure may enable VP patients to have a vaginal delivery instead of C-section. conditions: Vasa Previa conditions: Pregnancy Complications conditions: Maternal; Procedure conditions: In Utero Procedure Affecting Fetus or Newborn studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 20 type: ESTIMATED name: Fetoscopic Laser Photocoagulation measure: Mode of delivery measure: Gestational age at delivery measure: Successful visualization and mapping of vasa previa measure: The rate of successful coagulation of the vasa previa - intraoperative imaging measure: The rate of successful coagulation of the vasa previa - postoperative imaging measure: The rate of successful coagulation of the vasa previa - pathology measure: Placental function measure: GA at hospital admission measure: Duration of hospital stay measure: Cause for hospital admission measure: The rate of spontaneous preterm labor measure: The rate of preterm premature rupture of membranes (PPROM) measure: The rate of placental abruption measure: The rate of chorioamnionitis measure: The rate of chorioamniotic separation measure: Interval from procedure to delivery measure: The rate of fetal growth restriction measure: Fetal brain structure measure: The rate of NICU admission measure: NICU length of stay measure: Short term neonatal morbidity measure: Neonatal survival measure: Maternal mental health score measure: Postnatal examination of the placenta sex: FEMALE minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: Boston Children's Hospital city: Boston state: Massachusetts zip: 02115 country: United States lat: 42.35843 lon: -71.05977 hasResults: False
nctId: NCT06290219 id: CF23509A briefTitle: The Effect of Platelet-rich Plasma Nasal Injection in the Treatment of Traumatic Olfactory Dysfunction acronym: PRP overallStatus: NOT_YET_RECRUITING date: 2024-03-20 date: 2024-09-30 date: 2024-12-31 date: 2024-03-04 date: 2024-03-04 name: Taichung Veterans General Hospital class: OTHER briefSummary: The purpose of this study is to explore the efficacy of injecting high-concentration platelet plasma combined with hyaluronic acid into the nasal olfactory mucosa in the treatment of traumatic anosmia. conditions: Traumatic Olfactory Nerve Injury With Anosmia (Diagnosis) conditions: Effect of Drug studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 80 type: ESTIMATED name: platelet-rich plasma combined with hyaluronic acid name: Zinc Gluconate 10 MG Oral Tablet name: 4 bottles of phenyl ethyl alcohol, lemon, eucalyptus, and clove oil measure: phenyl ethyl alcohol odor detection threshold test measure: traditional Chinese version of University of Pennsylvania Smell Identification Test (TC-UPSIT) measure: Visual Analogue Scale sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Taichung Veterans General Hospital city: Taichung zip: 40705 country: Taiwan name: Rong-San Jiang, MD, PhD role: CONTACT phone: 800-555-5555 phoneExt: 4088 email: rsjiang@vghtc.gov.tw name: Kai-Li Liang, MD role: CONTACT phone: +886423592525 phoneExt: 82620 email: kellyliang1107@gmail.com name: Rong-San Jiang, MD, PhD role: PRINCIPAL_INVESTIGATOR lat: 24.1469 lon: 120.6839 hasResults: False
nctId: NCT06290206 id: UU_IRB_00161649 id: 1R01CA279973-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R01CA279973-01 id: DSS_10065815 type: OTHER domain: University of Utah, Document Summary Sheet (DSS) Number briefTitle: PREVENT HPV-Related Cancers acronym: PREVENT overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2026-12-30 date: 2027-06-01 date: 2024-03-04 date: 2024-03-29 name: University of Utah class: OTHER name: Kaiser Permanente name: University of Arizona name: Sea Mar Community Health Centers name: National Cancer Institute (NCI) briefSummary: This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West. Once implemented into practice, our intervention could significantly reduce disparities in the burden of HPV-associated cancers among rural populations in the United States. The proposed study will assess the effectiveness of clinic-based outreach to increase vaccination rates for HPV at four community clinics in rural counties in Washington. The proposed study includes the following: (1) boot camp translation to tailor messaging based on patient and provider input; (2) PREVENT randomized controlled trial (RCT) that will assign adult parent/caregiver participants to a timeline for receiving intervention; and (3) qualitative interviews with parents/caregivers, providers, and other healthcare team members and development of best practices, implementation guides and dissemination of findings for other clinics to implement the program on a broader scale. At the end of the trial, personal interviews with parents/caregivers, clinical staff, and providers will be conducted to understand reactions to the program and persistent barriers to initiating and completing HPV vaccination. conditions: Vaccine Hesitancy conditions: HPV Vaccination conditions: Vaccine; Uptake conditions: Vaccination; Series Completion conditions: Vaccine Refusal studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: The investigators will use intervention mapping (IM) to plan each intervention step. The investigators will apply IM to develop and test HPV vaccination reminders for parents/caregivers (P/C). Bootcamp Translation (BCT) will engage diverse stakeholders using an iterative schedule of meetings. The BCT process will define the format and content of vaccination messages.