hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06260280 id: 4 briefTitle: Chronic Sleep Deprivation and Changes in Cortical and Hippocampal Volume overallStatus: NOT_YET_RECRUITING date: 2024-02-26 date: 2024-05-26 date: 2024-06-01 date: 2024-02-15 date: 2024-02-15 name: Instituto Mexicano del Seguro Social class: OTHER_GOV briefSummary: Sleep is a physiological state that is essential for human performance, including academic, occupational, interpersonal, and psychological aspects. Sleep disruption or deprivation leads to a loss of psychomotor skills and an increased association with various diseases. Therefore, it is critical to assess how chronic sleep deprivation affects medical residents who work long shifts, including those assigned during their training. conditions: Sleep Deprivation conditions: Hippocampal Atrophy conditions: Cortical Irregularity studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 37 type: ESTIMATED name: Cerebral Nuclear Magnetic Resonance measure: Change in Hippocampal volumetry. measure: Change in cortical volumetry sex: ALL minimumAge: 24 Years maximumAge: 30 Years stdAges: ADULT facility: Unidad Medica de Alta Especialidad No. 1, Bajío city: Leon state: Guanajuato zip: 37260, country: Mexico lat: 21.12908 lon: -101.67374 hasResults: False
nctId: NCT06260267 id: 000417 briefTitle: A Phase 1b Proof-of-concept Trial Exploring the Effects of FE 999322 and FE 999324 in Adults With Mild to Moderate Ulcerative Colitis overallStatus: RECRUITING date: 2024-03-12 date: 2025-09-15 date: 2025-09-15 date: 2024-02-15 date: 2024-04-05 name: Ferring Pharmaceuticals class: INDUSTRY briefSummary: To explore the safety of FE 999322 (microbiota suspension) and FE 999324 (microbiota capsule) versus placebo in subjects with active mild to moderate ulcerative colitis (UC). conditions: Ulcerative Colitis studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR count: 90 type: ESTIMATED name: Microbiota suspension name: Microbiota capsule name: Placebo suspension name: Placebo capsule measure: Treatment-emergent adverse events from baseline to week 52 sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ferring Investigational Site status: RECRUITING city: North Little Rock state: Arkansas zip: 72117 country: United States name: Global Clinical Compliance role: CONTACT lat: 34.76954 lon: -92.26709 facility: Ferring Investigational Site status: RECRUITING city: Jacksonville state: Florida zip: 32256 country: United States name: Global Clinical Compliance role: CONTACT lat: 30.33218 lon: -81.65565 facility: Ferring Investigational Site status: RECRUITING city: Oklahoma City state: Oklahoma zip: 73102 country: United States name: Global Clinical Compliance role: CONTACT lat: 35.46756 lon: -97.51643 hasResults: False
nctId: NCT06260254 id: 244826201 briefTitle: Effects of Railway Vibration on Sleep and Disease acronym: BioVib overallStatus: RECRUITING date: 2024-02-05 date: 2024-06-30 date: 2024-12-31 date: 2024-02-15 date: 2024-02-21 name: Göteborg University class: OTHER name: University of Pennsylvania name: University of Manitoba briefSummary: This study will investigate the biological mechanisms linking sleep disruption by vibration and noise, and the development of cardiometabolic disease. In a laboratory sleep study, the investigators will play railway vibration of different levels during the night. The investigators will also measure objective sleep quality and quantity, cognitive performance across multiple domains, self-reported sleep and wellbeing outcomes, and blood samples. Blood samples will be analyzed to identify metabolic changes and indicators of diabetes risk in different nights. Identifying biomarkers that are impacted by sleep fragmentation will establish the currently unclear pathways by which railway vibration exposure at night can lead to the development of diseases in the long term, especially metabolic disorders including diabetes. conditions: Noise Exposure conditions: Sleep Disturbance conditions: Sleep Hygiene conditions: Metabolic Disturbance conditions: Cognitive Change conditions: Glucose Metabolism Disorders (Including Diabetes Mellitus) conditions: Vibration; Exposure studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: All participants will be exposed to each of the different vibration conditions. Each study night is treated as a separate arm of the crossover study. The order of the vibration exposure conditions will be be randomly assigned across participants using a Latin square design to avoid first-order carryover effects. Each subject will be exposed to one night of each of the following:
Quiet night: No noise or vibration will be played, serving as a control night to assess individual baseline sleep, metabolic profile, and cognitive performance; Three railway vibration nights to determine consequences of noise-disrupted sleep. The vibration level in these three nights will be 0.5 mm/s, 0.7 mm/s and 0.9 mm/s respectively, so that exposure-response relationships can be derived. primaryPurpose: BASIC_SCIENCE masking: DOUBLE maskingDescription: Participants will be aware that in any given study night they can be exposed to railway vibration and noise. They will not be informed what exposure condition will occur in any given night, but they can become unblinded to the exposure if they are awake, as they will may hear the noise or feel the vibration.
nctId: NCT06260241 id: ShaikhZayedH briefTitle: Gain in Stretched Penile Length After Phalloplasty With & Without Penile Traction in Children. overallStatus: RECRUITING date: 2023-01-01 date: 2025-01-01 date: 2025-01-01 date: 2024-02-15 date: 2024-02-15 name: Shaikh Zayed Hospital, Lahore class: OTHER briefSummary: The goal of this Randomized Controlled Trial is to assess the gain in stretched penile length after phalloplasty with \& without penile traction in children of age group 4 to 13 years presenting in hospital with the complaint of concealed penis.
• Gain in stretched penile length after phalloplasty with and without penile traction in children. conditions: Concealed Penis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized Control Trial primaryPurpose: OTHER masking: SINGLE whoMasked: PARTICIPANT count: 70 type: ESTIMATED name: Traction Dressing name: Without Traction Dressing measure: The gain in stretched penile length (SPL) sex: MALE minimumAge: 4 Years maximumAge: 13 Years stdAges: CHILD facility: Sheikh Zayed Hospital status: RECRUITING city: Lahore state: Punjab country: Pakistan name: ADEEL AHMED, MBBS MS role: CONTACT phone: 00923491467739 email: numberdar12@gmail.com lat: 31.558 lon: 74.35071 hasResults: False
nctId: NCT06260228 id: STUDY02002270 briefTitle: HOme-Based Self-management and COgnitive Training CHanges Lives (HOBSCOTCH)-Parkinson's Disease (HOBSCOTCH-Parkinson's) acronym: HOBSCOTCH-PD overallStatus: RECRUITING date: 2024-01-05 date: 2024-08-01 date: 2024-11-30 date: 2024-02-15 date: 2024-02-15 name: Dartmouth-Hitchcock Medical Center class: OTHER briefSummary: The goal of this pilot study is to assess the feasibility of adapting and delivering the existing home-based epilepsy self-management intervention, HOBSCOTCH, for people with Parkinson's Disease (PD)
* complete a brief Satisfaction Survey after the entire HOBSCOTCH-PD program conditions: Parkinson Disease conditions: Cognitive Dysfunction conditions: Memory Disorders studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 5 type: ESTIMATED name: HOme-Based Self-management and COgnitive Training CHanges lives (HOBSCOTCH) measure: Change in quality of life as measured by comparing PDQ-39 (Parkinson's Disease Questionnaire) scores pre- and post-HOBSCOTCH-PD intervention. measure: Change in subjective cognition as measured by comparing Neuro-QOL Item Bank v2.0 Cognitive Function scores pre- and post-HOBSCOTCH-PD intervention. sex: ALL minimumAge: 30 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Dartmouth-Hitchcock status: RECRUITING city: Lebanon state: New Hampshire zip: 03756 country: United States name: Sarah J Kaden role: CONTACT phone: 603-540-5824 email: sarah.j.kaden@hitchcock.org lat: 43.64229 lon: -72.25176 hasResults: False
nctId: NCT06260215 id: FFH briefTitle: Recovery Kinetics Following a Soccer Training in Middle-aged Males overallStatus: RECRUITING date: 2024-02-05 date: 2024-02-26 date: 2024-03-09 date: 2024-02-15 date: 2024-02-21 name: University of Thessaly class: OTHER briefSummary: This study aims at investigating the recovery kinetics of skeletal muscle damage, neuromuscular fatigue and performance following a single soccer trainning session in middle aged males. The participants will perform a soccer training session \[A single training session including 60 minutes of warm up, soccer technical exercises and small-sided game\] and a cotrol trial (No intervention included, only daily measurements) in randomized, repeated measures, crossover design. Assesesments related to skeletal muscle damage, performance and neuromuscular fatigue will be executed before the training session and daily for four consecutive days after training. conditions: Skeletal Muscle Damage studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: OTHER masking: NONE count: 11 type: ESTIMATED name: ST measure: Change in White blood cell count measure: Change in Granulocyte cell count measure: Change in Platelets cell count measure: Change in Monocyte cell count measure: Change in Lymphocyte cell count measure: Change in percentage of Hematocrit level measure: Change Red blood cells count measure: Change in Hemoglobin level measure: Change in Creatine kinase activity measure: Change in Total antioxidant capacity measure: Change in Glutathione concentration in blood measure: Change in countermovement jump height measure: Change in Peak power during coutermovement jump test measure: Change in isometric peak torque of knee extensors and flexors measure: Change in sprint time of 10 m measure: Change in sprint time of 30 m measure: Change in delayed onset of muscle soreness measure: Dietary intake measure: Peak Maximal oxygen consumption (Peak VO2) measure: Body Mass measure: Body Height measure: Body Fat measure: Lean body mass measure: Bone mass density measure: Bone mass content measure: Field activity during the soccer training measure: Heart rate during the soccer training measure: Systolic Blood Pressure measure: Dystolic Blood Pressure measure: Rest Heart Rate sex: MALE minimumAge: 40 Years maximumAge: 60 Years stdAges: ADULT facility: University o Thessaly, School of Physical Education and Sports Science status: RECRUITING city: Tríkala zip: 42100 country: Greece name: Athanasios Z Jamurtas, Prof role: CONTACT phone: +30 24310 47054 email: ajamurt@pe.uth.gr name: Ioannis G Fatouros, Prof role: CONTACT phone: +30 24310 47047 email: ifatouros@pe.uth.gr name: Athanasios S Poulios, PhD role: PRINCIPAL_INVESTIGATOR lat: 39.55493 lon: 21.76837 hasResults: False
nctId: NCT06260202 id: 308.273 briefTitle: Nutrition Under Noninvasive Ventilation acronym: NUTRINIV overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-05-31 date: 2024-05-31 date: 2024-02-15 date: 2024-02-16 name: Università degli Studi del Piemonte Orientale "Amedeo Avogadro" class: OTHER briefSummary: Even though nutrition is a fundamental component of Intensive care unit (ICU) therapy, critically ill patients are frequently malnourished, a factor well known for its strong association with a higher risk of complications, prolonged ICU/hospital length of stay, and greater ICU readmission and mortality rates. Noninvasive ventilation (NIV) use has increased considerably over the past twenty years, making this supportive technique a keystone of acute respiratory failure (ARF) treatment. In this setting, respiratory support is provided through an interface, usually a mask or a helmet, that frequently represents an important obstacle to nutrition delivery, making oral intake impossible and posing the necessity to start enteral (EN) or parenteral nutrition (PN). Moreover, while critical care guidelines regarding nutritional management of patients receiving mechanical ventilation (MV) are well established, data and recommendations about the appropriate nutritional support to patients in NIV are still very limited. Due to this limited data, we want to describe characteristics and nutritional management of patients undergoing NIV in ICU, and to evaluate the difference between the mean caloric and protein intake of these patients and the recommended caloric and protein target for critically ill patients. Secondarily, we want to evaluate the difference of the caloric and protein intake among groups of patients undergoing different nutritional modality and to assess potential associations of the nutritional characteristics with patient outcomes. conditions: Noninvasive Ventilation conditions: Nutrition Therapy conditions: Respiratory Insufficiency studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 112 type: ESTIMATED measure: Caloric and protein gap measure: Nutrition modalities outcomes sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06260189 id: Soh-Med-24-01-02MD briefTitle: Assessment Of Serum And Tissue Levels Of Cold-Inducible RNA-Binding Protein In Patients With Lichen Planus overallStatus: RECRUITING date: 2024-02 date: 2025-02 date: 2025-10 date: 2024-02-15 date: 2024-02-15 name: Sohag University class: OTHER briefSummary: Lichen planus (LP) is a chronic inflammatory mucocutaneous disease of unknown etiology.
Pathogenesis of LP is not completely understood, but it's considered a T-cell-mediated autoimmune disease. Cold-inducible RNA binding protein (CIRP or CIRBP) is a member of the glycine-rich RNA-binding protein family, Recent studies proved that CIRP acts as a tumor promoter through its actions on different cellular proliferation levels, Recently, the role of the damage associated molecular proteins and cytokines was highlighted in the pathogenesis of many disorders including psoriasis, alopecia areata, vitiligo, rheumatoid arthritis, other autoimmune diseases as well as several types of cancer. The aim of this study is to compare serum and tissue levels of CIRP in patients with LP and healthy controls. conditions: Assessment, Self studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: CROSS_SECTIONAL count: 80 type: ESTIMATED measure: Assessment of cold-inducible RNA binding protein levels in serum and tissue sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Aya Ahmed Elsayed status: RECRUITING city: Sohag zip: 82511 country: Egypt name: Aya A Elsayed, Msc role: CONTACT phone: 00201060094631 phoneExt: Egypt email: aya_shando@yahoo.com lat: 26.55695 lon: 31.69478 hasResults: False
nctId: NCT06260150 id: ZXT briefTitle: Application of IPC During Surgery to Prevent Venous Thrombosis in Gastrointestinal Surgery Patients. overallStatus: ACTIVE_NOT_RECRUITING date: 2023-04-01 date: 2024-04 date: 2024-04 date: 2024-02-15 date: 2024-02-15 name: Feng Tian class: OTHER_GOV briefSummary: The goal of this clinical trial is to evaluate the effectiveness of intraoperative intermittent pneumatic compression (IPC) device usage in preventing lower extremity deep vein thrombosis (DVT) in patients undergoing gastrointestinal surgery.The main question it aims to answer is provide a reference basis for determining the efficacy of IPC application during gastrointestinal surgery for preventing lower extremity DVT in patients.
Participants are patients who require gastrointestinal surgery, specifically for the resection of gastrointestinal tumors. They will be divided into a control group and an experimental group. The experimental group will use an Intermittent Pneumatic Compression (IPC) device during surgery, while the control group will receive standard treatment. The objective is to observe whether the use of IPC during surgery can prevent the formation of Deep Vein Thrombosis (DVT) or lower the Risk of DVT. conditions: Gastrointestinal Neoplasms conditions: Stomach Neoplasms conditions: Intestinal Neoplasms studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 120 type: ESTIMATED name: Intermittent Pneumatic Compression Devices measure: Incidence rate of DVT measure: Length of surgery measure: Intraoperative body temperature measure: Amount of bleeding during surgery sex: ALL minimumAge: 18 Years maximumAge: 99 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Shandong Provincial Hospital city: Jinan state: Shandong zip: 250021 country: China lat: 36.66833 lon: 116.99722 hasResults: False
nctId: NCT06260137 id: UludagThorax briefTitle: Comparison of Two Different Methods for Reducing Pain After Lung Surgery overallStatus: ACTIVE_NOT_RECRUITING date: 2023-07-10 date: 2024-07 date: 2024-08 date: 2024-02-15 date: 2024-02-15 name: Uludag University class: OTHER briefSummary: The goal of this clinical study is to compare the effectiveness of the Rhomboid Intercostal Block and Sub-Servitus plan block and the effectiveness of the Rhomboid intercostal block in patients with video-supported thoracoscopic surgery. The main question it aims to answer is:
Which of these two blocks more effectively reduces the patients' pain? conditions: Postoperative Analgesia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: SINGLE whoMasked: PARTICIPANT count: 60 type: ESTIMATED name: Rhomboid intercostal block name: Rhomboid intercostal and subserratus plane block measure: Postoperative analgesia sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Hastane city: Bursa zip: 16210 country: Turkey lat: 40.19559 lon: 29.06013 hasResults: False
nctId: NCT06260124 id: Greek Dancing-UTH briefTitle: Acute Physiological Effects of Greek Traditional Dancing overallStatus: NOT_YET_RECRUITING date: 2024-04-10 date: 2024-06-30 date: 2024-10-30 date: 2024-02-15 date: 2024-04-09 name: University of Thessaly class: OTHER briefSummary: In Greece, people of different age groups, including young children to older adults, are involved in traditional dance. To date, the well-know benefits of dancing include entertainment, socialization and increased physical activity. However, the acute effects of Greek traditional dancing on health, physical performance and muscle damage indices remain largely unknown. Therefore, the aim of this project is to evaluate the acute effect of Greek traditional dancing on health-, physical performance-, and muscle damage-related parameters by considering the impact of dancing tempo (slow vs moderate vs fast). In a crossover repeated measures design 10 pre- and 10 post-menopausal women will participate in the three dancing sessions of different tempo in a random order. conditions: Menopause conditions: Cardiovascular Health conditions: Body Composition conditions: Physical Performance conditions: Muscle Damage studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: BASIC_SCIENCE masking: NONE count: 20 type: ESTIMATED name: Slow tempo name: Moderate tempo name: Fast tempo measure: Change in blood pressure measure: Change in perceived exertion measure: Change in blood lactate measure: Change in resting metabolic rate measure: Change in delayed-onset of muscle soreness (DOMS) measure: Change in maximal isometric voluntary contraction measure: Change in joint range of motion measure: Change in functional performance measure: Change in white blood cell count measure: Change in granulocyte count measure: Change in lymphocytes measure: Change in monocytes measure: Change in creatine kinase concentration measure: Change in reduced glutathione measure: Change in oxidized glutathione measure: Change in catalase activity measure: Change in protein carbonyls measure: Change in total antioxidant capacity measure: Change in heart rate measure: Change in oxygen consumption measure: Change in physical activity measure: Change in red blood cell count measure: Change in hematocrit measure: Change in hemoglobin sex: FEMALE minimumAge: 20 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06260111 id: SA23I0021 briefTitle: Photobiomodulation for Oral Mucositis and Functional Impairments During Hematopoietic Stem Cell Transplantation acronym: POMFITT overallStatus: NOT_YET_RECRUITING date: 2024-04-10 date: 2025-10-30 date: 2025-10-30 date: 2024-02-15 date: 2024-02-15 name: Universidad del Desarrollo class: OTHER name: Agencia Nacional de Investigación y Desarrollo name: Clínica Dávila briefSummary: The goal of this clinical trial is to test the efficacy of laser photobiomodulation in adult hematologic cancer patients undergoing hematopoietic stem cell transplantation (HSCT). The main questions it aims to answer are: • Is photobiomodulation with laser in the oral cavity, compared to standard care, effective in preventing oral mucositis and functional impairments in adult patients receiving HSCT? • What is the level of patient´s acceptability of photobiomodulation with laser in the oral cavity during HSCT? Participants once a day will receive photobiomodulation (diode laser device) in their oral cavity from the first day of transplantation conditioning until third day post-transplant. Researchers will compare with usual care to see if photobiomodulation helps preventing oral mucositis and functional impairment. conditions: Hematologic Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The design of the study consists of a randomized, controlled trial with parallel groups (photobiomodulation + usual care versus a control group with only usual care), allocation ratio of 1:1. primaryPurpose: PREVENTION masking: DOUBLE maskingDescription: Assessor will be blinded only for the secondary outcomes. The person responsible for statistical analyses will also be blinded. whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 30 type: ESTIMATED name: Photobiomodulation name: Usual care measure: Oral Mucositis measure: Level of Pain measure: Handgrip strength measure: Exercise tolerance measure: Physical fitness measure: Health related quality of life measure: Length of hospital stay measure: Use of opioids measure: Body mass index measure: Nutritional status measure: Daily calorie intake measure: Arm circumference measure: Triceps skinfold sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Clinica Dávila city: Santiago state: Metropolitana zip: 8431657 country: Chile name: Tomás A López-Espinoza, MSc.C. role: CONTACT phone: +56962056755 email: tlopeze@udd.cl name: Hernán López, MD role: CONTACT phone: +56966795985 email: hernan.lopez@davila.cl name: Monica Peña, Nurse role: SUB_INVESTIGATOR lat: -33.45694 lon: -70.64827 hasResults: False