hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06326177 id: Yeditepe U - Poyraz Tuncer briefTitle: Investigating Association Between Spine, Scapular, Shoulder and Core in Swimmers overallStatus: ENROLLING_BY_INVITATION date: 2024-06-15 date: 2024-07-01 date: 2024-09-01 date: 2024-03-22 date: 2024-03-27 name: Yeditepe University class: OTHER briefSummary: The aim of this observational study is to investigate relationship between cervical, thoracic, lumbar and thoracolumbar spine posture, spine movement, isometric and eccentric shoulder strength, scapular dyskinesis and core muscle endurance in healthy competitive young swimmers in comparison with healthy recreational swimmers. The main question is whether spine posture affects spine movement, shoulder strength, scapular dyskinesia and core endurance. Participants will asked to complete a warm up period, after that spine posture, spine movement, scapular dyskinesia, shoulder strength and core endurance will be assessed by examiner. Researchers will compare competitive swimmer group and recreational swimmer group. Additionally correlation between spine posture, spine movement, scapular dyskinesia, shoulder strength and core muscle endurance will be investigated in competitive swimmer group. Aim of the study is to determine whether posture have any effect upon these parameters. conditions: Postural Kyphosis conditions: Postural Lordosis conditions: Movement, Abnormal conditions: Spine Injury conditions: Cervical Lordosis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 44 type: ESTIMATED name: Spine Posture Assessment name: Spine Movement Assessment name: Core Muscle Endurance Assessment name: Scapular Dyskinesia name: Shoulder Strength measure: Spinal Posture measure: Cervical Movement measure: Thoracic Movement measure: Lumbar Movement measure: Thoracolumbar Movement measure: Anterior Core Musculature Assessment measure: Lateral Core Musculature Assessment measure: Posterior Core Musculature Assessment measure: Core Musculature Ratio Assessment measure: Shoulder Strength Assessment measure: Shoulder Strength Ratio Assessment measure: Scapular Dyskinesia sex: ALL minimumAge: 12 Years maximumAge: 24 Years stdAges: CHILD stdAges: ADULT facility: PT Academy city: Istanbul state: Kadıköy zip: 34744 country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06326164 id: sample briefTitle: Effect of Kinesio-taping of Lower Limbs overallStatus: RECRUITING date: 2024-02-15 date: 2024-06-15 date: 2024-07-18 date: 2024-03-22 date: 2024-03-22 name: Kafrelsheikh University class: OTHER briefSummary: The goal of this clinical trail is to test if kinesio-taping on lower limbs has an effect on balance and gait in children with diplegic cerebral palsy. Children in study group will have designed physiotherapy for gait and balance, the control group will have designed physiotherapy in addition to kinesio-taping on both lower limbs. conditions: Cerebral Palsy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 40 type: ESTIMATED name: kinesio-taping. name: A designed physiotherapy program. measure: Change in gait. measure: Change in balance. sex: ALL minimumAge: 6 Years maximumAge: 10 Years stdAges: CHILD facility: Asmaa Mohamed Khalil Sedeek status: RECRUITING city: Kafr Ash Shaykh country: Egypt name: asmaa M khalil role: CONTACT phone: 01101011588 email: asmaakhalil011010@gmail.com lat: 31.11174 lon: 30.93991 hasResults: False
nctId: NCT06326151 id: UMAPS-UDATO briefTitle: Interdisciplinary Psychoeducational Intervention Programme for Caregivers of Dependent Older Adults overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2025-09-01 date: 2025-12-31 date: 2024-03-22 date: 2024-03-22 name: University of Salamanca class: OTHER briefSummary: Background: Caring for an older dependent adult with cognitive impairment can have negative consequences for the family caregiver. Interdisciplinary interventions are necessary to address their needs jointly and comprehensively. While attempts have been made to improve their situation from different disciplines in isolation, a collaborative approach is required to ensure the best possible outcome.
Methods: A parallel, randomized, controlled clinical trial with two arms will be conducted at the Occupational Therapy Teaching and Care Unit (UDATO) and the Municipal Psychosocial Support Unit for the Elderly (UMAPS), both of which belong to the University of Salamanca and are in agreement with the City Council of Salamanca, Spain. The trial will also be conducted at the University Care Centre of Salamanca (CAUSA). People aged 60 years or older will be recruited as family caregivers of dependent older adults with cognitive impairment in a chronic situation. Participants will be divided into two groups: the intervention group (IG) will carry out an interdisciplinary psychoeducational programme from the perspective of psychology and occupational therapy, and the control group (CG) will carry out a controlled follow-up. Participants will complete 12 sessions over a period of 3 months, followed by three monthly reinforcement sessions after the intervention. At the beginning and end of the intervention, participants will be assessed and socio-demographic data will be collected along with the following scales: the Spanish version of the Caregiver Burden Interview (CBI), the Spanish version of the Center for Epidemiologic Studies-Depression Scale (CES-D), the Psychosocial Support Questionnaire adaptation (PSQ), the General Health Questionnaire (GHQ), the World Health Organization Quality of Life Assessment - AGE (WHOQOL-AGE) and the Bayer-Activities of Daily Living Scale (B-ADL).
Discussion: The objective of this study is to enhance conventional clinical practice for family caregivers of dependent older adults. This will be achieved through an interdisciplinary psychoeducational intervention that aims to reduce overload and depressive symptomatology, increase social support, improve health and perceived quality of life, and enhance understanding of the syndrome/illness. The intervention will also focus on managing difficult situations associated with day-to-day caregiving, managing emotions and associated erroneous beliefs, and promoting self-care. Additionally, the study aims to improve the functionality of the cared-for person. conditions: Dependent Older People conditions: Family Caregiver conditions: Interdisciplinary conditions: Intervention conditions: Occupational Therapy conditions: Psychoeducational conditions: Psychology studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE maskingDescription: The work of sequencing, randomisation, recruitment and allocation of the trial sample will be carried out by research staff who are not involved in the assessments or interventions of each group, thus avoiding any potential bias in the trial.
Participants will also be blinded and will not know which group they have been allocated to and therefore which intervention they will receive. In order to minimise any contamination between groups, the assessment process will be carried out by external research staff who will perform the measurements and who have been previously trained and educated to avoid subjective bias in the process, as they will be unaware of the intervention group to which they have been assigned, thus masking the blinded assessment by third parties in the clinical trial. In addition, the researchers responsible for the statistical analysis of the trial will be blinded in order to increase the rigour of the trial process and thus the scientific quality. whoMasked: OUTCOMES_ASSESSOR count: 70 type: ESTIMATED name: Interdisciplinary Psychoeducational Programme name: Health Education Programme measure: Mini Mental State Examination (MMSE) measure: Barthel Index measure: Caregiver Burden Interview measure: Centre for Epidemiological Studies Depression Scale measure: Adaptation of the Psychosocial Support Questionnaire measure: General Health Questionnaire measure: World Health Organization Assessment of Quality of Life - AGE (WHOQOL-AGE) measure: The Bayer-Activities of Daily Living Scale (B-ADL) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Eduardo Jose Fernandez Rodriguez city: Salamanca state: Castilla Y Leon zip: 37002 country: Spain name: Eduardo PhD Fernandez, PhD role: CONTACT phone: 923294500 email: edujfr@usal.es lat: 40.96882 lon: -5.66388 hasResults: False
nctId: NCT06326138 id: 22121 briefTitle: Pharmacokinetics and Pharmacodynamics of Edoxaban Before and After Bariatric Surgery acronym: EXPOSE overallStatus: WITHDRAWN date: 2024-03-11 date: 2024-03-11 date: 2024-03-11 date: 2024-03-22 date: 2024-03-22 name: Institut universitaire de cardiologie et de pneumologie de Québec, University Laval class: OTHER briefSummary: The study will be conducted at a single site in the Canada, Quebec. Participants will be recruited from the bariatric surgery clinic and will be required to be either, waiting for sleeve gastrectomy surgery (n=12, restrictive bariatric surgery, Group 1) or Roux-en-Y gastric bypass (n=12, mixed bariatric surgery, Group 1), or had underwent Roux-en-Y gastric bypass 12 ± 3 months ago (n=12, Group 2).
Participants in Group 1, edoxaban pharmacokinetic and pharmacodynamics will be evaluated before and 48 ± 5 hours after bariatric surgery (sleeve gastrectomy and Roux-en-Y gastric bypass). Participants in Group 2, edoxaban pharmacokinetic and pharmacodynamics will be evaluated only once, at 12 ± 3 months following their Roux-en-Y gastric bypass.
All participants will be received single oral doses of 60 mg edoxaban at each pharmacokinetic and pharmacodynamics evaluation. conditions: Bariatric Surgery Candidate studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Group 1: 12 patients waiting for a sleeve gastrectomy surgery and 12 patients waiting for a Roux-en-Y gastric bypass surgery.
Group 2: 12 patients 12 months after Roux-en-Y gastric bypass surgery. primaryPurpose: OTHER masking: NONE count: 0 type: ACTUAL name: Edoxaban Pharmacokinetics and Pharmacodynamics measure: Pharmacokinetics edoxaban parameter measure: Pharmacokinetics edoxaban parameter measure: Pharmacokinetics edoxaban parameter measure: Pharmacokinetics edoxaban parameter measure: Pharmacodynamics edoxaban parameter measure: Pharmacodynamics edoxaban parameter measure: Pharmacodynamics edoxaban parameter sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06326125 id: SherzadSH briefTitle: Pharmacology and Non-pharmacology Approaches in Reducing Children's Pain and Fear During Painful Procedures overallStatus: ENROLLING_BY_INVITATION date: 2023-12-15 date: 2024-04-10 date: 2024-04-10 date: 2024-03-22 date: 2024-03-28 name: Uppsala University class: OTHER briefSummary: This study Will contribute in the knowledge of pediatric nurses during painful procedures such venipuncture conditions: Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: TRIPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 160 type: ESTIMATED name: TICK-B name: TKTX-Cream name: TICK-B and TKTX-C measure: severity of Pain measure: Fear sex: ALL minimumAge: 6 Years maximumAge: 12 Years stdAges: CHILD facility: Sherzad Khudeida Suleman city: Duhok state: Erbil zip: 42012 country: Iraq lat: 36.86709 lon: 42.98845 hasResults: False
nctId: NCT06326112 id: 4588 briefTitle: Role of Active Deresuscitation After Resuscitation: acronym: RADAR-Canada overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-03-31 date: 2025-06-30 date: 2024-03-22 date: 2024-03-22 name: Unity Health Toronto class: OTHER name: Canadian Institutes of Health Research (CIHR) briefSummary: The RADAR-Canada trial is a pilot RCT undertaken to assess the acceptability of, compliance with, and biologic consequences of a deresuscitation protocol designed to expedite the removal of excess interstitial fluid in patients who remain in a positive fluid balance following admission to an intensive care unit (ICU). conditions: Fluid Overload conditions: Critical Illness conditions: Sepsis conditions: ARDS conditions: Trauma studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: RADAR-Canada is a parallel group CT in which study participants are randomized in a 1:1 ratio to protocolized deresuscitation or usual care primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Masking of the health care team will not be feasible as they must administer the intervention whoMasked: OUTCOMES_ASSESSOR count: 120 type: ESTIMATED name: Furosemide Injection name: Metolazone Tablets measure: Efficacy: Mean cumulative fluid balance measure: Compliance with deresuscitation protocol measure: Acceptability of protocol measure: All cause mortality measure: New onset organ dysfunction measure: Organ support-free days measure: Inflammatory and renal biomarkers - change from baseline values sex: ALL minimumAge: 18 Years maximumAge: 120 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Unity Health Toronto city: Toronto state: Ontario zip: M5B 1W8 country: Canada name: John C Marshall, MD role: CONTACT phone: 4168645225 email: john.marshall@unityhealth.to lat: 43.70011 lon: -79.4163 hasResults: False
nctId: NCT06326099 id: R34AA030655 type: NIH link: https://reporter.nih.gov/quickSearch/R34AA030655 briefTitle: Brief Binge Eating and Drinking Online Intervention overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-04-30 date: 2026-04-30 date: 2024-03-22 date: 2024-03-22 name: University of Southern California class: OTHER briefSummary: This pilot project targets both binge drinking and binge eating behavior in college students through a mobile-based online program that provides students with evidence-based intervention material designed to reduce the incidence of both behaviors and encourage students to seek more formal in-person counseling. conditions: Binge Eating conditions: Binge Drinking studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 300 type: ESTIMATED name: Brief Online Binge Eating and Drinking Intervention measure: Frequency of past 28-day binge drinking measure: Frequency of past 28-day binge eating measure: Brief Young Adult Alcohol Consequences Questionnaire (B-YAACQ) measure: Mental Health/Substance Use Disorder Treatment History Inventory sex: ALL minimumAge: 18 Years maximumAge: 24 Years stdAges: ADULT hasResults: False
nctId: NCT06326086 id: REC.65-080-7-1 briefTitle: Differences in Rate of Decline in CT-defined Skeletal Muscle Mass and Physical Performance in Patients With Advanced Non-small Cell Lung Cancer Receiving Chemotherapy and Targeted Therapy/Immunotherapy, Before and After Treatment. overallStatus: RECRUITING date: 2022-08-01 date: 2024-08-01 date: 2024-08-01 date: 2024-03-22 date: 2024-03-22 name: Prince of Songkla University class: OTHER briefSummary: Lung cancer is a common disease leading to 18 % of cancer deaths worldwide. Despite various improvement in treatment, there still remains low 5-year survival rate of 10-20 % in advanced lung cancer patients. Skeletal muscle mass and physical performance have been shown to effect overall survival and prognosis in lung cancer. This research focuses on effects of different treatment of lung cancer such as chemotherapy, targeted therapy and immunotherapy on skeletal muscle mass and physical performance. conditions: Advanced Lung Cancer conditions: Sarcopenia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 240 type: ESTIMATED name: Chemotherapy drug name: Targeted Agent name: Immunotherapy measure: To determine the differences in the rate of decline in CT defined skeletal muscle index at L3 vertebra and physical performance in advanced NSCLC patients receiving chemotherapy and targeted therapy/ immunotherapy, before and after treatment. measure: To determine validity of gender based cut off for CT-defined skeletal muscle index at L3 lumbar vertebra (L3SMI) based on recommendation of JSH/AWGS in Thai population. measure: 2. To determine baseline association between CT-defined skeletal muscle index at L3 lumbar vertebra (L3SMI) and physical performance using SPPB in advanced NSCLC patients. measure: 4. To determine differences in rate decline in skeletal muscle mass using CT-defined skeletal muscle index at L3 lumbar vertebra (L3SMI) in patients receiving first line chemotherapy (CMT) and other line chemotherapy (OCMT). sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Prince of Songkla University status: RECRUITING city: Hat Yai state: Songkla zip: 90110 country: Thailand lat: 7.00836 lon: 100.47668 hasResults: False
nctId: NCT06326073 id: OMUKAEK2019/324 briefTitle: Interaction Between Smoking, GCF Periostin, IL17A, IL17E and Non-surgical Periodontal Therapy overallStatus: COMPLETED date: 2019-07-01 date: 2021-02-01 date: 2021-07-01 date: 2024-03-22 date: 2024-03-22 name: Ondokuz Mayıs University class: OTHER briefSummary: It was aimed to evaluate the changes in the levels of Periostin, IL-17A and IL-17E cytokines in the gingival crevicular fluid (GCF) of periodontitis patients which non-surgical (Phase I) periodontal treatment applied to and their interactions with smoking. The study included systemic healthy smokers(SP)(n:11) and non-smokers(P)(n:11) with periodontitis, smokers (SS)(n:11) and non-smokers(S)(n:11) with periodontal healthy individuals Phase I periodontal treatment was applied to the groups with periodontitis. Before treatment (day 0), clinical measurements evaluating periodontal status were recorded and GCF samples were collected. GCF samples were collected from the same tooth regions on the 15th and 30th days after treatment and clinical measurements were repeated. GCF Periostin, IL-17A and IL-17E levels were determined by ELISA method. All data were evaluated statistically. conditions: Periodontitis conditions: Smoking studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The study included systemic healthy smokers(SP)(n:11) and non-smokers(P)(n:11) with periodontitis, smokers (SH)(n:11) and non-smokers(H)(n:11) with periodontal healthy individuals primaryPurpose: DIAGNOSTIC masking: NONE count: 44 type: ACTUAL name: Non Surgical Periodontal Treatment measure: Evaluation of Periostin levels measure: Evaluation of IL-17A levels measure: Evaluation of IL-17E levels measure: Interaction Between Smoking and GCF Periostin, IL17A, IL17E levels sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ondokuz Mayıs University Faculty of Dentistry Department of Periodontology city: Samsun zip: 55270 country: Turkey lat: 41.27976 lon: 36.3361 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2024-03-16 uploadDate: 2024-03-16T11:54 filename: Prot_SAP_000.pdf size: 206405 hasResults: False
nctId: NCT06326034 id: AAA234 briefTitle: Impact of Dapagliflozin as Add-on Therapy on Glycemic Status and Quality of Life in Type 2 Diabetic Patients overallStatus: COMPLETED date: 2022-05-01 date: 2023-01-01 date: 2023-01-01 date: 2024-03-22 date: 2024-03-22 name: Mohammed Mahmood Mohammed class: OTHER briefSummary: Type 2 Diabetes Mellitus (T2DM) is a syndrome of metabolic dysregulation that needs a multifactorial behavioral and pharmacological treatments to prevent or delay complications, morbidity and mortality. Uncontrolled hyperglycemia can be negatively affecting the patient's physical and psychological status and thus lower the patient's quality of life (QoL) (Verma \& Dadarwal, 2017)(Vanstone et al., 2015)(Gebremedhin et al., 2019). According to American Diabetes Association (ADA), when hyperglycaemia remain uncontrolled (HbA1c ≥1.5% above the glycemic target), a second therapy for T2DM is needed (Davies et al., 2022).
It has been certained by ADA, beside the glucose lowering effect the add-on antidibetic medication should have an impact on weight management to achieve and maintain the optimum glycemic and weight control which are the goals in people without established cardiorenal risks (Vijan et al., 2014((Inzucchi et al., 2012). Although metformin still the first-line pharmacotherapy in most T2DM patients, according to American Diabetes Association (ADA) (Association, 2020) but has little or even weight neutral effect, as well as gliptins (Hermansen \& Mortensen, 2007)(Sazan et al., 2012). Other old antidibetic classes such as thiazolidinediones (TZDs) and sulfonylureas (SUs) inspite of their efficacy in controlling glycemia but their use is associated with weight gain and other adverse effects (Derosa \& Maffioli, 2010)(Najim et al., 2014)(Fonseca, 2003). However, The newest class of antidibetic drugs, sodium-glucose cotransporter 2 inhibitors (SGLT2i), are approved for the treatment of T2DM as add-on or even initial therapy (Tamez-Pérez et al., 2013). This class is act by inducing glycosuria and thus improving glycemic status without affecting insulin level (Merovci et al., 2015). Dapagliflozin is a highly selective inhibitor of SGLT2. It has been well tolerated and its safety and efficacy approved in the clinical trials, mostly on cardio-renal outcomes with additional benefits of weight loss and low risk of hypoglycemia (Heerspink et al., 2020)(Solomon et al., 2022)(Wiviott et al., 2019)(McMurray et al., 2019). To date, no clinical data regarding SGLT2i recorded in Iraqi patients with limited data available on Arabic population. On Qatari, assessment of Dapagliflozin effectiveness revealed a significant improvement in the glycemic status after 6 months when used in combination with standard therapy, a reduction (Al AdAwi et al., 2019). In Saudi Arabia, Dapagliflozin was found to be well-tolerated and effective treatment option for T2DM patients after 6 months (Alguwaihes, 2021). conditions: Diabetic Nephropathy Type 2 studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: This interventional randomized clinical study was conducted from May to December 2022, at the National Diabetic Centre for treatment and research/ Mustansiriyah University/ Baghdad/ Iraq. Ethical approval from the diabetic center and college of pharmacy/ Mustansiriyah University, was taken prior to the study initiation. All investigations/ procedures carried out in this study involving human participants were in accordance with the 1975 Declaration of Helsinki and its later amendments. primaryPurpose: TREATMENT masking: NONE count: 40 type: ACTUAL name: Dapagliflozin measure: Quality of Life Assessment tool sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mohammed Mahmood Mahmood city: Baghdad zip: 00964 country: Iraq lat: 33.34058 lon: 44.40088 hasResults: False