hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06265506 id: 20320 id: R01AA031013 type: NIH link: https://reporter.nih.gov/quickSearch/R01AA031013 briefTitle: Virtual Incentive Treatment for Alcohol acronym: VITA overallStatus: NOT_YET_RECRUITING date: 2024-02-19 date: 2027-04-03 date: 2028-04-04 date: 2024-02-20 date: 2024-02-20 name: Washington State University class: OTHER name: The University of Texas Health Science Center at San Antonio name: Weill Medical College of Cornell University name: National Institute on Alcohol Abuse and Alcoholism (NIAAA) briefSummary: The overall objective of this program of research is to utilize phosphatidylethanol (PEth), a blood-based biomarker that can detect alcohol use for up to 28 days to deliver a feasible telehealth-based 26-week CM intervention. This study will test a telehealth PEth-based CM model in a sample of adults with AUD (n=200), recruited via online platforms by randomizing individuals to six months of 1) an online cognitive behavioral therapy for AUD (CBT4CBT) and telehealth PEth-based CM (CM condition) or 2) CBT4CBT and reinforcers for submitting blood samples (no abstinence required) (control condition). Investigators will assess group differences in PEth-defined abstinence and regular excessive drinking (PEth \>= 200 ng/mL), and alcohol-related harms (e.g., smoking, drug use). This study will address important gaps in CM research by assessing outcomes during a 12-month follow-up, which is much longer than most previous CM studies; using a conceptual model to identify predictors of post-treatment abstinence. Investigators will conduct an economic analysis to place the cost of this model in the context of downstream CM-associated cost-offsets and improvements in personal and public health. conditions: Alcohol Use Disorder conditions: Alcohol Drinking conditions: Alcohol Abuse conditions: Alcohol Dependence studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: We will test the efficacy of our CM model against an evidence-based online intervention, CBT4CBT, by randomizing participants to six months of:
2. CBT4CBT and reinforcement for PEth tests that are consistent with alcohol abstinence (CM Condition). primaryPurpose: TREATMENT masking: NONE count: 200 type: ESTIMATED name: Contingency Management name: Computer Based Training for Cognitive Behavioral Therapy for AUD (CBT4CBT) measure: Aim 1) Alcohol Abstinence & Aim 3) Predictors: PEth-Defined Alcohol Abstinence During CM (Aim 1) and Follow-Up (Aim 3) measure: Aim 2) Alcohol-Related Harms: Addiction Severity Index (ASI) Lite measure: Aim 2) Alcohol-Related Harms: Patient Health Questionnaire-9 (PHQ-9) measure: Aim 2) Alcohol-Related Harms: Generalized Anxiety Disorder-7 (GAD-7) measure: Aim 2) Alcohol-Related Harms: Short Form Health Survey-12 (SF-12) measure: Aim 2) Alcohol-Related Harms & Aim 4) Cost Analysis: Non-study Medical and Other Services (NMOS) form measure: Aim 2) Alcohol Related Harms: Fagerstrom measure: Aim 2) Alcohol Related Harms: Urine Drug Tests measure: Aim 2) Alcohol Related Harms: Perceived Stress Scale (PSS-10) measure: Aim 3) Predictors: Demographics measure: Aim 3) Predictors: Addictions Neuroclinical Assessment (ANA) Questionnaire measure: Aim 3) Predictors: TestMyBrain measure: Aim 3) Predictors: Positive Negative Affect Schedule (PANAS) measure: Aim 3) Predictors: Situational Confidence Questionnaire-8 (SCQ-8) measure: Aim 3) Predictors: Alcohol Craving VAS measure: Aim 4) Cost Analysis: Drug Abuse Treatment Cost Analysis Program (DATCAP) measure: Aim 4) Cost Analysis: PROPr measure: Aim 1) Alcohol Abstinence: Regular excessive drinking measure: Aim 1) Alcohol Abstinence: uEtG-Defined Alcohol Abstinence measure: Aim 1) Alcohol Abstinence: Self-reported Alcohol Abstinence and Heavy Drinking measure: Additional Implementation Data: Attrition measure: Additional Implementation Data: CSQ-8 measure: Adverse Events measure: Computer Based Training for Cognitive Behavioral Health (CBT4CBT) Program Use sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Washington State University city: Spokane state: Washington zip: 99201 country: United States name: Michael McDonell, PhD role: CONTACT phone: 509-368-6967 email: mmcdonell@wsu.edu lat: 47.65966 lon: -117.42908 hasResults: False
nctId: NCT06265493 id: PLAGH-AOC-L02 briefTitle: Postoperative Infectious Complications Calculator for Elderly Patients overallStatus: COMPLETED date: 2021-06-01 date: 2023-06-30 date: 2023-09-30 date: 2024-02-20 date: 2024-03-19 name: Weidong Mi class: OTHER briefSummary: The investigators established a first-ever convenient scoring system for clinicians to assess the risk of Postoperative infectious complications (PICs) for elderly patients. Our scoring system can aid in the early detection of potential risks for postoperative infections. Higher-score patients were more likely to experience postoperative infections. conditions: Postoperative Infection conditions: Geriatrics conditions: Prediction studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 37230 type: ACTUAL measure: Postoperative Infectious Complications Calculator for Elderly Patients sex: ALL minimumAge: 65 Years stdAges: OLDER_ADULT facility: Depatment of Anesthesiology, The First Medical Center Affiliation: Chinese PLA General Hospital city: Beijing state: Beijing zip: 100853 country: China lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06265480 id: 2023-04577-01 briefTitle: FallFitness Fallprevention Program for Older Adults overallStatus: RECRUITING date: 2024-03-01 date: 2025-07-01 date: 2025-12-31 date: 2024-02-20 date: 2024-02-20 name: Dalarna University class: OTHER name: Sormland County Council, Sweden briefSummary: The overall aim with this project is to collaborate with four organisations for retired persons located in a small region of middle Sweden. The project aims to test and evaluate a newly developed group-based fall prevention exercise program regarding the effects and experiences of both leading and participating in the intervention. The design of the study is a randomised controlled trial including a total of 100 participants (60+), 50 participants in the intervention and 50 participants in the control group. conditions: Fall Injury conditions: Fall conditions: Self Efficacy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomised Controlled Trial primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Study will be singled blinded (assessors) whoMasked: OUTCOMES_ASSESSOR count: 100 type: ESTIMATED name: FallFitness intervention group measure: Physical function by Short Physical Performance Battery measure: Self-efficacy (balance confidence) measure: Fear of Falling measure: EuroQoL-5 Dimension Questionnaire (EQ-5D) measure: Fallfrequency measure: Falling techniques measure: Handgrip strength sex: ALL minimumAge: 60 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Marina Arkkukangas status: RECRUITING city: Eskilstuna state: Sormland country: Sweden name: Marina Arkkukangas, PhD role: CONTACT phone: +46 (0)706468868 email: maau@du.se name: Michail Tonkonogi, Professor role: CONTACT phone: +46(0)708206435 email: mtn@du.se lat: 59.36661 lon: 16.5077 hasResults: False
nctId: NCT06265467 id: 28909108800228 briefTitle: Evaluation of Two Different Techniques for Sinus Elevation, Open Versus Closed . overallStatus: COMPLETED date: 2022-01-01 date: 2023-02-01 date: 2023-07-01 date: 2024-02-20 date: 2024-02-20 name: Misr International University class: OTHER name: Suez Canal University briefSummary: A clinical Trial, comparing two different techniques to elevate the maxillary sinus floor membrane to allow for simultaneous dental implant placement in the severely atrophied maxillary ridges.Both using allogenic bone substitute as the bone graft material. One technique is the open lateral window technique and the second is the closed crestal technique. conditions: Alveolar Ridge Augmentation conditions: Sinus Floor Augmentation conditions: Maxillary Sinus studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Parallel Assignment primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: it is a double blinded study, both the outcome assessor and statistician will be blinded whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 30 type: ACTUAL name: Closed Sinus Elevation name: Open Sinus Elevation measure: Implant Stability measure: Radiographic bone gain sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Suez Canal University city: Ismailia zip: 41522 country: Egypt lat: 30.60427 lon: 32.27225 hasResults: False
nctId: NCT06265454 id: LDAED IN MC briefTitle: Low Dose Atropine Eye Drops in Myopic Egyptian Children acronym: LAMP overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2025-12-30 date: 2026-03-30 date: 2024-02-20 date: 2024-02-20 name: Ain Shams University class: OTHER briefSummary: Previous Studies reported that low concentration atropine eye drops may be effective in increasing the choroidal blood flow and thickness and this slows myopia progression.
purpose of the study is to compare changes in axial length, anterior chamber depth, choroidal thickness, central corneal thickness and anterior scleral thickness among myopic children receiving atropine 0.05% or 0.01% and placebo. conditions: Myopia Progression conditions: Axial Length, Eye conditions: Sclera Thickness studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 75 type: ESTIMATED name: low dose atropine eye drops name: Placebo measure: change in the average Choroidal Thickness over follow up period. sex: ALL minimumAge: 6 Years maximumAge: 12 Years stdAges: CHILD facility: Ain shams university city: Cairo state: Abbasia zip: 11517 country: Egypt name: Aya MA Abd El wahab, Masters role: CONTACT phone: 1009192526 phoneExt: +20 email: ayamah711@gmail.com name: Marwa M Abd al Karim, MD role: PRINCIPAL_INVESTIGATOR lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06265441 id: MS42/2024 briefTitle: Comparison of Pain Relief Post Knee Arthroscopy Using IPACK + Adductor Canal Block vs. Adductor Canal Block Alone overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-09-01 date: 2024-10-01 date: 2024-02-20 date: 2024-02-26 name: Ain Shams University class: OTHER briefSummary: In this study, the invistigators aim to compare postoperative analgesia effectiveness between combined interspace between the popliteal artery and posterior capsule of the knee block (IPACK) and Adductor canal block vs. Adductor canal block alone after Arthroscopic knee surgeries focusing on VAS score assessment at 8 hours postoperative. conditions: Postoperative Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: Group A will receive adductor canal block after spinal anesthesia under a high-frequency ultrasound guidance in which the adductor canal is identified and 20 ml of 0.25% bupivacaine will be injected name: Group B will receive adductor canal block under ultrasound guide 20 ml bupivacaine 0.25% and IPACK block under direct visualization of ultrasound of 20 ml bupivacaine 0.25% measure: Assessment of pain using the visual analogue scale (VAS) upon first ambulation after 8 hours from the completion of the surgical procedure and skin closure. measure: Total analgesics consumption measure: The time till first analgesic requirement measure: The range of movement (ROM) measure: The number of steps sex: ALL minimumAge: 20 Years maximumAge: 40 Years stdAges: ADULT facility: Ain Shams University city: Cairo state: Abbassia zip: 00202 country: Egypt name: Mohamed Morsi, M.B.B.CH role: CONTACT phone: +201116618163 email: MohamedMorsi@med.asu.edu.eg name: Mohamed Morsi, M.B.B.CH role: PRINCIPAL_INVESTIGATOR lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06265428 id: DB-1303-O-3001 id: CTR20233403 type: OTHER domain: CENTER FOR DRUG EVALUATION, NMPA briefTitle: A Study to Compare DB-1303/BNT323 Versus T-DM1 in Breast Cancer overallStatus: RECRUITING date: 2024-01-29 date: 2026-02 date: 2026-02 date: 2024-02-20 date: 2024-02-20 name: DualityBio Inc. class: INDUSTRY name: BioNTech SE briefSummary: This study is designed to compare efficacy and safety of DB-1303/BNT323 versus T-DM1 in HER2-positive, unresectable and/or metastatic breast cancer patients previously treated with trastuzumab and taxane. conditions: HER2-positive Breast Cancer studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 224 type: ESTIMATED name: DB-1303/BNT323 name: T-DM1 measure: Progression Free Survival (PFS) by Blinded Independent Central Review (BICR) assessment per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) measure: Overall Survival (OS) measure: Progression Free Survival (PFS) by Investigator assessment per RECIST 1.1 measure: Objective response rate (ORR) by BICR and investigator assessment per RECIST 1.1 measure: Duration of response (DoR) by BICR and investigator assessment per RECIST 1.1 measure: PK parameters: maximum observed concentration (Cmax) measure: PK parameters: time to maximum concentration (Tmax) measure: Adverse events (AEs) measure: Patient reported outcomes (PROs): European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ) - C30 measure: Patient reported outcomes (PROs): EORTC QLQ-BR45 measure: Patient reported outcomes (PROs): European Quality of Life Five Dimension Five Level Scale (EQ-5D-5L) measure: European Quality of Life Five Dimension Five Level Scale (EQ-5D-5L) measure: Anti-drug antibodies (ADA) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The Fifth Medical Center of the Chinese People's Liberation Army General Hospital status: NOT_YET_RECRUITING city: Beijing state: Beijing zip: 100039 country: China name: Zefei Jiang role: CONTACT lat: 39.9075 lon: 116.39723 facility: Fudan University Shanghai Cancer Center status: RECRUITING city: Shanghai state: Shanghai zip: 200032 country: China name: Jian Zhang role: CONTACT lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06265415 id: Soh-Med-24-01-07MS briefTitle: Comparative Study of Intravenous Labetalol Versus Intravenous Nitroglycerin Versus Sublingual Nifedipine overallStatus: NOT_YET_RECRUITING date: 2024-03-30 date: 2025-03-30 date: 2025-03-30 date: 2024-02-20 date: 2024-02-20 name: Sohag University class: OTHER briefSummary: Pre-eclampsia (PE) is one of the most frequent pregnancy complications and is one of the main causes of maternal and fetal morbidity and mortality in its severe form.control of blood pressure is of crucial importance to avoid maternal and fetal complications.Therapeutic modalities that can target the underlying pathophysiological changes and reverse the endothelial dysfunction could help to ameliorate the systemic manifestations in patients with severe PE. Either Intravenous labetalol and nitroglycerine as well as sublingual nifedipine have been frequantly used for the management of acute severe hypertension in PE conditions: Severe Preeclampsia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 60 type: ESTIMATED name: Labetalol name: Nitroglycerine name: Nifedipine measure: duration of control blood pressure sex: FEMALE minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT hasResults: False
nctId: NCT06265402 id: 36264 briefTitle: Retrolaminar Block Versus Tab Block in Abdomioasty overallStatus: RECRUITING date: 2024-01-15 date: 2025-10-15 date: 2025-12-15 date: 2024-02-20 date: 2024-02-20 name: Tanta University class: OTHER briefSummary: The aim of the study is to compare the analgesic efficacy of Us guided retrolaminar block versus transversus abdominis plane block in patient under going abdominal plastic surgery conditions: Block studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 90 type: ESTIMATED name: Tab block versus retrolaminar block in abdominal plastic surgery measure: Total dose of morphine consumption in the first postoperative 24hours sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: TantaU U status: RECRUITING city: Tanta country: Egypt name: Hadeel Elsagheer, Master role: CONTACT lat: 30.78847 lon: 31.00192 hasResults: False
nctId: NCT06265389 id: Pentoxifylline in pneumonia briefTitle: Pentoxifylline as an Adjuvant Therapy in the Treatment of Pediatric Pneumonia; A New Perspective of an Old Drug overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-08-31 date: 2024-10-30 date: 2024-02-20 date: 2024-02-20 name: Tanta University class: OTHER briefSummary: Pentoxifylline is a xanthine-derived, commercially produced drug approved for the management of intermittent claudication in patients suffering from a chronic occlusive arterial disease of the limbs. Pentoxifylline has been documented to display anti-inflammatory and immunomodulatory effects, as well as some antithrombotic and antiviral effects. This drug has also been shown to reduce lung fibrosis in patients with COVID-19, as well as to prevent thromboembolic events. This work aims to assess the benefit of oral Pentoxifyllin supplementation, in addition to standard antibiotic and other supportive therapy, in the management of hospitalized children with community-acquired pneumonia conditions: Pentoxifylline as an Adjunct Therapy in the Treatment of Pneumonia studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 100 type: ESTIMATED name: Pentoxifylline Oral Tablet measure: Respiratory distress measure: Temperature measure: Oxygen saturation measure: CRP measure: LDH measure: D-dimer measure: Interleukin 6 measure: Hospital stays measure: Pneumonia complications measure: Surgical intervention sex: ALL minimumAge: 2 Months maximumAge: 18 Years stdAges: CHILD stdAges: ADULT hasResults: False
nctId: NCT06265376 id: IRB22-046 briefTitle: Do Patient Educational Videos Improve Pain and Recovery After Laparoscopic Hysterectomy? overallStatus: RECRUITING date: 2023-03-13 date: 2024-05-01 date: 2024-07-01 date: 2024-02-20 date: 2024-02-20 name: Benaroya Research Institute class: OTHER briefSummary: The use of multi-model patient education has been used in a variety of medical specialties to educate patients on expectations for various medical procedures and improve patients' understanding of their own health care. However, it is unknown what type of audio and/or visual materials work best in a given clinical setting. By surveying overall pain/post-operative recovery satisfaction we can measure how well our video intervention educates and reinforces post-operative management at home when compared to the current method of education that patients receive at the pre-operative visit prior to laparoscopic hysterectomy at this institution. conditions: Pain, Postoperative studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 100 type: ESTIMATED name: Educational Video measure: Overall satisfaction score (5 point Likert scale) with post operative pain control after laparoscopic hysterectomy measure: Pain score at the time of survey completion (0=no pain 10=worst pain measure: Average pain score for the first 7 days as perceived by the patients (likert scale) measure: Number of post-op phone calls received measure: Number of post-op emergency room visits measure: Number of readmissions measure: Number of patients with steri-strips still in place measure: Number opioids taken since surgery measure: Overall satisfaction with pre-operative education regarding surgery (5 point Likert scale) measure: ding surgery (5 point likert scale) Overall satisfaction with educations regarding what to expect post-operatively (5 point Likert scale) sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Virginia Mason Medical Center status: RECRUITING city: Seattle state: Washington zip: 98101 country: United States name: Michelle Gruttadauria, MD role: CONTACT phone: 206-223-6191 email: Michelle.Gruttadauria@virginiamason.org lat: 47.60621 lon: -122.33207 hasResults: False
nctId: NCT06265350 id: Liver Project 5 briefTitle: Cryoablation Combined With Cardonilizumab and Bevacizumab in Hepatocellular Carcinoma With Pulmonary Metastases overallStatus: RECRUITING date: 2024-02-02 date: 2026-01-30 date: 2027-01-30 date: 2024-02-20 date: 2024-02-20 name: Sun Yat-sen University class: OTHER briefSummary: This study intends to evaluate the efficacy and safety of cryoablation combined with Cardonilizumab and Bevacizumab in hepatocellular carcinoma with pulmonary metastases. conditions: Hepatocellular Carcinoma conditions: Liver Cancer Stage IV conditions: Pulmonary Metastases conditions: Cadonilimab conditions: Bevacizumab conditions: Cryoablation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 80 type: ESTIMATED name: Cadonilimab name: Bevacizumab name: Cryoablation measure: Objective response rate (ORR) measure: Progression free survival (PFS) measure: Overall survival (OS) sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sun Yat-sen University Cancer Center status: RECRUITING city: Guanzhou state: Guangdong zip: 510000 country: China name: Qunfang Zhou, MD role: CONTACT phone: 86 19868000115 email: zhouqun988509@163.com facility: Sun Yat-sen University Cancer Center status: RECRUITING city: Guanzhou state: Guangdong zip: 510000 country: China name: Qunfang Zhou, MD role: CONTACT phone: 8619868000115 email: zhouqun988509@163.com hasResults: False
nctId: NCT06265337 id: LAMETA-OGTT briefTitle: Does Co-administration of Lactate to an Oral Glucose Tolerance Test Lower the Glucose Response? overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2025-01 date: 2025-01 date: 2024-02-20 date: 2024-02-20 name: University of Aarhus class: OTHER briefSummary: To investigate whether co-administration of lactate with a glucose load affects postprandial glucose levels/handling, gastrointestinal hormones, gastric emptying, and appetite sensations in individuals with pre-diabetes when compared to placebo.