In a subgroup of patients advanced hemodynamic parameters will be recorded using pulse-contour analysis before, during and after surgery. Blood samples will also be collected in these patients at fixed intervals and analyzed for amongst others inflammation and cardiac dysfunction. conditions: Other Specified Disorders of Kidney and Ureter conditions: Benign Neoplasm of Ureter conditions: Calculus of Kidney and Ureter conditions: Ureter Cancer conditions: Ureteric Reflux conditions: Congenital Ureteric Anomaly conditions: Benign Renal Neoplasm conditions: Renal Cancer studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 220 type: ESTIMATED name: spinal analgesia with morphine and bupivacaine name: lidocaine infusion measure: QoR-15 score at postoperative day 1 measure: QoR-15 score preoperatively measure: QoR-15 score at postoperative day 7 measure: Pain (NRS) in rest and during motion 2hrs after arrival to the PACU measure: Pain (NRS) on POD 1-3 measure: Pain (NRS) in rest and during motion at POD 7 measure: Time from arrival in the OR to start of surgery measure: Time from end of surgery until leaving the OR measure: Incidence of unplanned termination of the lidocaine infusion measure: Amount of remifentanil in patients given remifentanil measure: Amount of intraoperative opioids in patients not receiving remifentanil measure: Length of stay at the PACU measure: Amount of opioids administred at the PACU measure: Percentage of patients with PONV requiring treatment at 0-6 hours and 6-24 hours postoperatively as well as during the whole postoperative stay measure: "Time out-of-bed" on POD 1-3 measure: Amount of opioids administered during the first 24 hours at the ward measure: First POD passing gases measure: First POD passing stool measure: Incidence of pruritus measure: Length of stay measure: DAOH30 measure: Postoperative complications untill POD 30 measure: Requirement for opioids after discharge measure: Incidence of respiratory depression leading to the use of a mu-antagonist within 48 hours of induction of anesthesia measure: Intraoperative fluid balance measure: Time with low blood pressure during anesthesia measure: Lowest MAP within 10 minutes after induction of anesthesia measure: Highest MAP within 10 minutes of abdominal insufflation measure: Fraction of patients needing norepinephrine before start of surgery measure: Fraction of patients needing norepinephrine intraoperatively (later than 15 minutes after start of surgery) measure: Average infusion rate of norepinephrine, in patients receiving norepinephrine, before start of surgery measure: Average infusion rate of norepinephrine, in patients receiving norepinephrine, after start of surgery measure: Intraoperative Cardiac Index measure: Intraoperative Stroke Volume Index measure: Intraoperative Cardiac Power Index measure: Intraoperative dPmx measure: Intraoperative Pulse Pressure Variation measure: Intraoperative Stroke Volume Variation measure: Intraoperative Systemic Vascular Resistance Index measure: Intraoperative heart rate measure: Biochemical markers of inflammation sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University Hospital Linköping status: RECRUITING city: Linköping country: Sweden name: Martin Holmberg, MD role: CONTACT phone: +46101033932 email: martin.holmberg@regionostergotland.se lat: 58.41086 lon: 15.62157 hasResults: False