hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06260462 id: 10 years adrenal insufficiency briefTitle: Effects of Steroid Replacement Therapy on Metabolic, Cardiovascular and Bone Outcomes in Adrenal Insufficiency overallStatus: COMPLETED date: 2012-01-01 date: 2022-09-30 date: 2023-12-30 date: 2024-02-15 date: 2024-02-15 name: University of Palermo class: OTHER briefSummary: The current study is a randomized, open study aimed to compare the effects of conventional glucocorticoid replacement treatment and dual-release hydrocortisone on anthropometric, metabolic, cardiovascular and bone outcomes in treatment-naïve patients with primary adrenal insufficiency and secondary adrenal insufficiency in a 10 year-observation period. conditions: Adrenal Insufficiency studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 88 type: ACTUAL name: dual-release hydrocortisone name: Conventional glucocortidois measure: Change of body weight measure: Change of anthropometric parameters measure: Change of metabolic parameters measure: Change of insulin sensitivity parameters measure: Change of cardiovascular parameters measure: Change of bone metabolic parameters measure: Change of bone density measure: Change of vascular parameters sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06260449 id: Trematode briefTitle: Different Treatment Approaches of Presumed Trematode-Induced Uveitis overallStatus: ACTIVE_NOT_RECRUITING date: 2023-10-21 date: 2024-10-21 date: 2024-12-21 date: 2024-02-15 date: 2024-02-15 name: Assiut University class: OTHER briefSummary: Different Treatment Approaches of Presumed Trematode-Induced Uveitis including periocular injection and medical treatment Nd laser treatment conditions: Uveitis studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP interventionModelDescription: Single group tested by intervention and medical treatment primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 31 type: ESTIMATED name: Surgical removal measure: Surgical removal sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Assiut city: Assiut country: Egypt lat: 27.18096 lon: 31.18368 hasResults: False
nctId: NCT06260436 id: Tharwat gamal Mohamed briefTitle: Questionnaire of Lower Urinary Tract Symptoms Among Women Before and After Surgical Correction of Uterine Prolapse overallStatus: RECRUITING date: 2021-05-30 date: 2024-09-30 date: 2024-12-30 date: 2024-02-15 date: 2024-02-21 name: Assiut University class: OTHER briefSummary: . The study will include patients who underwent Pelvic reconstructive surgery for advanced pelvic organ prolapse (POP-Q ≥ 3). Data regarding preoperative evaluation, surgical procedure, and post-operative management will be collected. women will receive a follow up questionnaire. . The baseline questionnaire included data on age, urinary incontinence, daytime frequency, nocturia, postmicturition dribble, straining, urgency, incomplete bladder emptying, and hesitancy. Women were asked about leakage caused by coughing or sneezing, moving, lifting, sleeping, sexual intercourse, urgency, and rest. conditions: Pelvic Organ Prolapse studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 180 type: ESTIMATED measure: effect of surgical correction of pelvic organ prolapse on the lower urinary tract symptoms measure: effect of surgical correction of pelvic organ prolapse on the quality of life sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Assuit University status: RECRUITING city: Assiut state: Assuit zip: 2063045 country: Egypt name: tharwat gl mohamed role: CONTACT phone: 01151166826 email: tharwat.fares3@gmail.com name: tht tg mohamed role: CONTACT phone: 01017941889 email: tharwat.fares3@gmail.com name: abdelghaffar m mohamed, professor role: PRINCIPAL_INVESTIGATOR lat: 27.18096 lon: 31.18368 hasResults: False
nctId: NCT06260423 id: 18/1/2024 briefTitle: The Effect of Clinical Experience on the Quality of Obturation and Periapical Changes of Teeth Treated With Matched Cones in Combination With Bioceramic Sealer overallStatus: RECRUITING date: 2023-01-01 date: 2025-02-01 date: 2025-04-01 date: 2024-02-15 date: 2024-02-15 name: Al-Azhar University class: OTHER briefSummary: Evaluation of the impact of clinical experience on the quality of obturation and periapical changes of clinical cases using lateral compaction with bioceramic sealers and matched cone obturation with bioceramic sealers both clinically and radiographically. conditions: Obturation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 54 type: ESTIMATED name: Experienced dentist using lateral compaction with bioceramic sealer. name: Unexperienced dentist using lateral compaction with bioceramic sealer. name: Experienced dentist using Single cone with bioceramic sealer. name: Unexperienced dentist using Single cone with bioceramic sealer. measure: Postoperative pain assessment measure: Postoperative pain assessment measure: Postoperative pain assessment measure: Postoperative pain assessment measure: Postoperative pain assessment measure: The quality of obturation and the voids within the root canal filling sex: ALL minimumAge: 20 Years maximumAge: 40 Years stdAges: ADULT facility: Al-Azhar university status: RECRUITING city: Cairo zip: 11651 country: Egypt name: Mohamed Badr, Master role: CONTACT phone: 0201111777739 email: badrabueida@gmail.com lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06260410 id: 10512 id: NL84672.078.23 type: OTHER domain: CCMO briefTitle: Data Collection in Lutetium Treated Prostate Cancer: Recording of Progression and Tumor Characteristics acronym: LUTRAC overallStatus: RECRUITING date: 2024-02-20 date: 2027-02-01 date: 2027-02-01 date: 2024-02-15 date: 2024-04-22 name: Erasmus Medical Center class: OTHER briefSummary: This prospective study aims to collect data and blood biomarkers from patients undergoing Lu-PSMA therapy at the Erasmus MC. In doing so, it will provide real-world efficacy and safety data on the drug, gather dosimetry data and explore putative biomarkers to identify patients who most benefit from Lu-PSMA treatment. conditions: Prostate Cancer Metastatic studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 150 type: ESTIMATED name: Blood draw for ctDNA and circulating tumor cell collection. measure: Overall survival measure: Progression free survival measure: Heterogeneity of PSMA-positivity measure: Effect of CTC PSMA expression on response to treatment. measure: Effect of biomarkers in blood on response to treatment. measure: PSMA-PET scan data and response to treatment. sex: MALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Erasmus MC status: RECRUITING city: Rotterdam state: Zuid-Holland zip: 3015 CN country: Netherlands name: Stijn Koolen, PhD role: CONTACT phone: +31638740656 email: s.koolen@erasmusmc.nl lat: 51.9225 lon: 4.47917 hasResults: False
nctId: NCT06260397 id: analgesia for MRM surgeries briefTitle: Serratus Anterior Plane Block and Costotransverse Block for Analgesia Following Modified Radical Mastectomy Surgeries overallStatus: NOT_YET_RECRUITING date: 2024-02-28 date: 2025-02-28 date: 2025-03-30 date: 2024-02-15 date: 2024-02-26 name: Ain Shams University class: OTHER briefSummary: Adequate pain management following modified radical mastectomy (MRM) is crucial for early ambulation and patient satisfaction. Breast cancer is the most common malignancy in females, with an increasing incidence in recent years. Surgery is one of the mainstays of therapy for breast cancer, and modified radical mastectomy (MRM) is the most effective and common type of invasive surgical treatment. Post-mastectomy pain syndrome (PMPS) is a surgical complication of breast surgery characterized by chronic neuropathic pain. The aim of this study is to investigate the efficacy and safety of single injection CTB versus SAPB on post-operative acute pain as a part of a multimodal analgesia plan in patients undergoing MRM. conditions: Regional Anesthesia Morbidity studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 90 type: ESTIMATED name: serratus anterior plane block name: costotransverse block name: patient controlled analgesia measure: Visual Analogue Scale score at 0,6,12 and 24 hour post-operatively. visual analogue scale is a scale from 0 to 10, 0 represent no pain at all and 10 represent the worst pain measure: The total dose of nalbuphine consumption is used postoperatively per patient rescue analgesia for 24. sex: FEMALE minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT hasResults: False
nctId: NCT06260384 id: FMASU R 139/2022 briefTitle: Wolf-Parkinson-White Syndrome and Asymptomatic Pre-excitation in Africa (a Multicenter WPW African Registry) overallStatus: RECRUITING date: 2022-05-01 date: 2024-05-31 date: 2024-10-31 date: 2024-02-15 date: 2024-02-26 name: Ain Shams University class: OTHER briefSummary: The purpose of this prospective observational study is to characterize the clinical profile of patients with WPW syndrome and patients with asymptomatic WPW pattern on ECG in different African countries and how these patients are managed across Africa Participants would include many different ethnicities at centers where the number of cardiac patients treated is high. All patients attending outpatient cardiology clinics or referred to Cath Lab for electrophysiological studies who are diagnosed to have a Wolf-Parkinson white pattern on the ECG are either symptomatic or asymptomatic. All patients fulfilling the eligibility criteria will be approached by the research team and asked if they wish to take part in the study.
Then other data from the electrophysiological study and ablation will be filled in by the research team from the data systems of each center. conditions: Wolf Parkinson White Syndrome conditions: Arrythmias studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 500 type: ESTIMATED name: electrocardiogram measure: No recurrence of symptoms measure: Assessment of performance outcome of each center sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Ain shams university status: RECRUITING city: Cairo state: Outside US zip: 11851 country: Egypt name: Nabil M Farag, MD role: CONTACT phone: +201223102180 email: faragnabil@hotmail.com role: CONTACT email: lamallam.eps@gmail.com name: lamyaa E Allam, MD role: PRINCIPAL_INVESTIGATOR lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06260371 id: ORIGAMI briefTitle: National Observatory of Mycoplasma Infections in Children Under 18 Ages in France acronym: ORIGAMI overallStatus: RECRUITING date: 2023-09-01 date: 2030-09-01 date: 2030-09-01 date: 2024-02-15 date: 2024-02-15 name: Association Clinique Thérapeutique Infantile du val de Marne class: OTHER name: GPIP briefSummary: This study was set up because of an unusual increase in the number of cases of mycoplasma infections in France between June and November 2023.
Clinical data from children with mycoplasma infections will be collected to characterise this infection and facilitate hospital management. conditions: Mycoplasma Infections conditions: Hospitalized Children studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: RETROSPECTIVE count: 3000 type: ESTIMATED measure: Number of patients hospitalized for mycoplasma infections measure: medical characterisation of mycoplasma infections measure: Identify risk factors of serious infection measure: Identify predictive signs of serious infection measure: Type of complications measure: Patients outcome measure: healthcare used for infected children measure: treatment used during hospitalisation measure: clinical description of infected children measure: Type of mycoplasma involved in infected children measure: performance of complementary diagnostic tests for lung disorders measure: compare medical data collected during hospitalisation sex: ALL minimumAge: 1 Day maximumAge: 17 Years stdAges: CHILD facility: ACTIV status: RECRUITING city: Créteil zip: 94600 country: France name: Corinne Levy, MD role: CONTACT phone: 1 48 85 04 04 phoneExt: +33 email: corinne.levy@activ-france.fr name: Stéphane Béchet, MSc role: CONTACT phone: 1 48 85 04 04 phoneExt: +33 email: stephane.bechet@activ-france.fr lat: 48.78333 lon: 2.46667 hasResults: False
nctId: NCT06260358 id: 6043 briefTitle: Multidisciplinary Assesssment of Structured Report for Cervical Cancer Staging acronym: STRECC overallStatus: RECRUITING date: 2024-03-01 date: 2024-12-31 date: 2025-03-31 date: 2024-02-15 date: 2024-02-15 name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS class: OTHER briefSummary: This study aims to validate a structured report for cervical cancer anchored to the FIGO staging system. A structured report is hypothesized to aid in uniformly applying FIGO staging, reducing staging discrepancies and improving patient care and outcomes.
Furthermore, we believe that the participation of the clinicians will improve the quality of the report to minimize the need for multidisciplinary team discussion conditions: Cervical Cancer studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 30 type: ESTIMATED name: Survey measure: Efficacy of a contextual structured report measure: Difference between satisfaction rate with narrative and structured report; measure: Comparison Single items response rate (for items 6 to 12 of the questionnaire related to clinical information), on both narrative and structured reports; measure: Differences in the single 6-to-12 items response rate between structured and narrative reports. sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Advanced Radiology Center status: RECRUITING city: Rome zip: 00168 country: Italy name: Luca Russo role: CONTACT phone: +390630158637 email: luca.russso@unicatt.it lat: 41.89193 lon: 12.51133 hasResults: False
nctId: NCT06260345 id: CAPRICE briefTitle: CommunautAry Pediatric bacteRial Infection in Intensive CarE Unit acronym: CAPRICE overallStatus: RECRUITING date: 2024-01-01 date: 2030-01-01 date: 2030-01-01 date: 2024-02-15 date: 2024-02-15 name: Association Clinique Thérapeutique Infantile du val de Marne class: OTHER name: GFRUP (Groupe Francophone de Réanimation et d'Urgences Pédiatrique) name: GPIP : Groupe de Pathologies Infectieuses Pédiatriques name: Centre National de Référence des Streptocoques name: Centre National de Référence des Pneumocoques name: Centre National de Référence des Méningocoques et Haemophilus influenzae name: Centre National de Référence des staphylocoques name: Centre National de Référence des E. Coli briefSummary: Severe bacterial infections are a worldwide scourge. However, the epidemiology of this type of infection varies over time. It is therefore essential to monitor them in order to prevent them more effectively. At this time, in France, no monitoring exists for this kind of infections. conditions: Hospitalized Children conditions: Severe Infection conditions: Invasive Bacterial Infection studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 3000 type: ESTIMATED measure: number of pediatrics cases of severe communautary bacterial infections measure: medical characterisation of children hospitalized for severe communautary bacterial infection case measure: Identify risk factors of serious infection measure: Identify predictive signs of severe cases in infected children. measure: healthcare used for infected children measure: Type of complications measure: Patients outcome measure: treatment used during hospitalisation measure: Bacterial strain characterization sex: ALL maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Association Clinique Thérapeutique Infantile du val de Marne status: RECRUITING city: Créteil zip: 94600 country: France name: Corinne Levy, MD role: CONTACT phone: 1 48 85 04 04 phoneExt: +33 email: corinne.levy@activ-france.fr name: Stéphane Béchet, MsC role: CONTACT phone: 1 48 85 04 04 phoneExt: +33 email: stephane.bechet@activ-france.fr lat: 48.78333 lon: 2.46667 hasResults: False
nctId: NCT06260332 id: INST UNM 2302 id: 23-293 type: OTHER domain: UNM HSC IRB briefTitle: Physical Activity Intervention for the Improvement of Pain in Young, Hispanic Breast Cancer Survivors overallStatus: RECRUITING date: 2023-10-20 date: 2024-08-30 date: 2024-12-31 date: 2024-02-15 date: 2024-02-15 name: New Mexico Cancer Care Alliance class: OTHER name: University of New Mexico briefSummary: This clinical trial tests whether increased activity throughout the day can improve the chronic pain and associated symptoms that breast cancer survivors may experience after surgery. Staying active is a key factor of one's physical, mental, and social health and well-being. Moving more could also reduce pain and associated stress, anxiety, or depression. Using a fitness tracker may help patients to move around more, whether or not they choose to exercise. Information gathered from this study may help researchers learn how the use of a Fitbit tracker with health coaching may improve physical activity and reduce pain in young, Hispanic breast cancer survivors. conditions: Breast Cancer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 25 type: ESTIMATED name: Supportive Care (Fitbit) measure: Recruitment rate (Feasibility) measure: Retention rate (Feasibility) measure: Adherence rate (Feasibility) measure: Incidence of adverse events measure: Change in chronic post-surgical pain measure: Change in physical activity measure: Change in health-related quality of life (hrQOL) sex: FEMALE minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: University of New Mexico Comprehensive Cancer Center status: RECRUITING city: Albuquerque state: New Mexico zip: 87106 country: United States name: Ellen R Wojcik, MBA-HCM role: CONTACT email: ewojcik@salud.unm.edu name: Cheryl A Sampson, MBA role: CONTACT email: ChSampson@salud.unm.edu name: Jacklyn M Nemunaitis, MD role: PRINCIPAL_INVESTIGATOR name: Cindy K Blair, Ph.D. role: SUB_INVESTIGATOR lat: 35.08449 lon: -106.65114 hasResults: False
nctId: NCT06260319 id: C19-64 briefTitle: Decoding Developmental Disorders in Humams acronym: devodecode overallStatus: COMPLETED date: 2019-01-01 date: 2024-01-01 date: 2024-01-01 date: 2024-02-15 date: 2024-02-15 name: Institut National de la Santé Et de la Recherche Médicale, France class: OTHER_GOV name: Imagine Institute name: Commissariat A L'energie Atomique briefSummary: The DEVO-DECODE project aims to align our currently limited knowledge currently limited knowledge of the genetic architecture of developmental with our more advanced knowledge of their "phenome".
* Develop precise preclinical models for functional studies of pathophysiological pathways conditions: Genetic Diseases studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: RETROSPECTIVE count: 720 type: ACTUAL name: Whole genome sequencing and Genome-Epigenome-Phenome Associations measure: Primary objectives measure: secondary objectives 1 measure: secondary objectives 2 sex: ALL minimumAge: 1 Year maximumAge: 90 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Institut Imagine city: Paris zip: 75015 country: France lat: 48.85341 lon: 2.3488 hasResults: False
nctId: NCT06260306 id: STUDY00002568 briefTitle: Hip Activation vs. Hip Activation + Core Stabilization overallStatus: COMPLETED date: 2024-01-24 date: 2024-04-12 date: 2024-04-12 date: 2024-02-15 date: 2024-04-26 name: Louisiana State University Health Sciences Center Shreveport class: OTHER briefSummary: The purpose of this investigation is to compare the effects of a combined hip activation and core stabilization training home exercise program (HEP) versus a hip activation training HEP alone on lower extremity (LE) frontal plane mechanics in healthy individuals.
Specific Aim 4: To determine whether a dose-response relationship exists between HEP compliance and change on the FSDT, peak external knee abduction moment, and sEMG. conditions: Movement, Abnormal conditions: Lower Extremity Problem studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE maskingDescription: The PI who will be performing the data analysis will be blinded to participants' random group allocation. The other investigators who will be collecting the outcome data will know the group allocation. whoMasked: INVESTIGATOR count: 34 type: ACTUAL name: Hip activation home exercise program name: Hip activation plus core stabilization home exercise program measure: Forward Step Down Test (FSDT) measure: Maximal volitional isometric contraction (MVIC) via sensory electromyography (sEMG) of gluteus maximus (GMax) measure: Mean activation of GMax via sEMG measure: Peak activation of GMax via sEMG measure: MVIC via sEMG of gluteus medius (GMed) measure: Mean activation of GMed via sEMG measure: Peak activation of GMed via sEMG measure: MVIC via of transversus abdominis (TA) measure: Mean activation of TA via sEMG measure: Peak activation of TA via sEMG measure: Peak external knee abduction moment during drop landing task measure: Compliance with Home Exercise Program sex: ALL minimumAge: 22 Years stdAges: ADULT stdAges: OLDER_ADULT facility: LSU Health Sciences Center at Shreveport city: Shreveport state: Louisiana zip: 71103 country: United States lat: 32.52515 lon: -93.75018 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2023-12-07 uploadDate: 2024-01-18T21:23 filename: Prot_SAP_000.pdf size: 292995 hasResults: False
nctId: NCT06260293 id: 4-2022-0208 briefTitle: The Effect of Post-operative Exercise in Gastric Cancer Patients: A Randomized Controlled Trial (RCT) Study overallStatus: ACTIVE_NOT_RECRUITING date: 2023-01-03 date: 2024-04-30 date: 2024-04-30 date: 2024-02-15 date: 2024-02-15 name: Yonsei University class: OTHER briefSummary: Medical advancements are enhancing the survival rates of individuals with gastric cancer. The growing population of gastric cancer survivors underscores the importance of managing treatment-related after-effects and side effects. Diminished physical function in cancer patients, particularly following gastric cancer surgery, is linked to increased mortality. The substantial decline in physical activity post-surgery contributes to a notable reduction in cardiorespiratory fitness and lower extremity muscle strength. Early postoperative exercise has demonstrated positive outcomes in colorectal cancer patients, facilitating early hospital discharge and supporting long-term recovery. However, there is a paucity of research on the efficacy of early postoperative exercise in the context of gastric cancer. Therefore, this study aims to evaluate the impact of early postoperative exercise on physical function following gastric cancer surgery. conditions: Gastric Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 52 type: ACTUAL name: exercise measure: Shorts Physical Performance Battery(SPPB) sex: ALL minimumAge: 19 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Surgery, Yonsei University College of Medicine city: Seoul country: Korea, Republic of lat: 37.566 lon: 126.9784 hasResults: False