nctId: NCT06316609 id: AD2016-2027 briefTitle: Prenatal Exposure to Emerging Contaminants and Children's Atopic Dermatitis acronym: PECCAD overallStatus: ACTIVE_NOT_RECRUITING date: 2016-06 date: 2018-04-30 date: 2027-12-31 date: 2024-03-18 date: 2024-03-18 name: Children's Hospital of Fudan University class: OTHER name: Minhang Maternal and Children Health Care Hospital name: School of Public Health，Fudan University briefSummary: This prospective cohort study aims to investigate the association between prenatal blood levels of Emerging Contaminants and the five-year incidence of atopic dermatitis (AD) in offspring. conditions: Atopic Dermatitis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 456 type: ACTUAL name: Gestational Exposure to Emerging Contaminants (ECs) measure: atopic dermatitis: Infant atopic dermatitis incidence measure: atopic dermatitis measure: atopic dermatitis measure: atopic dermatitis measure: prenatal exposure to Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs) at early pregnancy measure: prenatal exposure to Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs) at mid pregnancy measure: prenatal exposure to Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs) at late pregnancy measure: prenatal exposure to Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs) at first trimester measure: prenatal exposure to Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs) at second trimester measure: prenatal exposure to Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs) at third trimester measure: Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs) in Umbilical cord whole blood measure: Umbilical cord serum Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs) measure: prenatal exposure to Organophosphate Flame Retardants (OPFRs) at early pregnancy measure: prenatal exposure to Organophosphate Flame Retardants (OPFRs) at mid pregnancy measure: prenatal exposure to Organophosphate Flame Retardants (OPFRs) at late pregnancy measure: prenatal exposure to Organophosphate Flame Retardants (OPFRs) at first trimester measure: prenatal exposure to Organophosphate Flame Retardants (OPFRs) at second trimester measure: prenatal exposure to Organophosphate Flame Retardants (OPFRs) at third trimester measure: Organophosphate Flame Retardants (OPFRs) in Umbilical cord whole blood measure: Umbilical cord serum Organophosphate Flame Retardants (OPFRs) measure: Infant skin barrier function (Transepidermal Water Loss, TEWL） measure: Infant skin barrier function (Transepidermal Water Loss, TEWL） measure: Infant skin barrier function (Transepidermal Water Loss, TEWL） measure: Infant skin barrier function (Stratum corneum hydration, SCH) measure: Infant skin barrier function (Stratum corneum hydration, SCH) measure: Infant skin barrier function (Stratum corneum hydration, SCH) measure: Infant skin barrier function (sebum content) measure: Infant skin barrier function (sebum content) measure: Infant skin barrier function (sebum content) measure: Infant skin barrier function (skin surface pH) measure: Infant skin barrier function (skin surface pH) measure: Infant skin barrier function (skin surface pH) measure: prenatal exposure to Microplastics at early pregnancy measure: prenatal exposure to Microplastics at mid pregnancy measure: prenatal exposure to Microplastics at late pregnancy measure: prenatal exposure to Microplastics at first trimester measure: prenatal exposure to Microplastics at second trimester measure: prenatal exposure to Microplastics at third trimester measure: Microplastics in Umbilical cord whole blood measure: Umbilical cord serum Microplastics measure: Allergic rhinitis measure: Asthma measure: Infantile hemangioma sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Children Hospital of Fudan University city: Shanghai state: Shanghai zip: 201102 country: China lat: 31.22222 lon: 121.45806 hasResults: False