hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06338488 id: KutahyaHSU-DRYNEEDLE-SHOULDER briefTitle: The Effectiveness of Dry Needling Treatment in Patients With Shoulder Myofascial Pain Syndrome overallStatus: NOT_YET_RECRUITING date: 2024-03-25 date: 2024-06-25 date: 2024-06-25 date: 2024-03-29 date: 2024-03-29 name: Kutahya Health Sciences University class: OTHER briefSummary: Myofascial pain can be diagnosed by the presence of one or more myofascial trigger points (MTrPs), defined as hyperirritable spots in taut bands of skeletal muscle fibers palpable by hand. The treatment of myofascial pain primarily relies on the inactivation of MTrPs, often through manual pressure techniques or dry needling. In manual pressure techniques, the physiotherapist applies increasing pressure directly to the MTrP. In dry needling, acupuncture-like filiform needles are applied to the same point. There are two types of dry needling: superficial dry needling, which penetrates only the skin and superficial muscle, and deep dry needling, which involves inserting a needle directly into the MTrP. The sole or adjunct effectiveness of dry needling treatment targeting the trapezius and infraspinatus muscles has been investigated, particularly in patients with shoulder myofascial pain syndrome. In the study we are planning, a double-blinded efficacy trial will be conducted in patients with shoulder myofascial pain syndrome, where real and sham dry needling applications will be performed under ultrasound guidance, with both the patient and the evaluator blinded. This study design has the potential to make a significant contribution to the literature in this field. conditions: Shoulder Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Prospective double-blind randomized sham-controlled study. primaryPurpose: TREATMENT masking: TRIPLE maskingDescription: In the dry needling application, patients will be blinded to the groups they are randomized into. The evaluator will also be unaware of which group the patients belong to. The practitioner will perform the procedures in both groups using ultrasound guidance, targeting the standard trigger points in the painful shoulder's trapezius and infraspinatus muscles in the study group, and targeting subcutaneous fatty tissue in the same regions in the sham group. whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 50 type: ESTIMATED name: Real dry needling name: Sham dry needling measure: Visual Analog Scale measure: Patient-Specific Functional Scale measure: Pressure Pain Threshold Measurement measure: The Shoulder Pain and Disability Index (SPADI) measure: The Quick DASH Outcome Measure measure: The 12-item Short-Form Health Survey version 2 (SF-12v2) sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06338475 id: 20205703 briefTitle: A Biobehavioral Intervention for Latino/Hispanic Young Adults With Cancer overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-06 date: 2026-06 date: 2024-03-29 date: 2024-03-29 name: University of California, Irvine class: OTHER briefSummary: Building upon the results of a single-arm trial designed to investigate the feasibility and acceptability of a novel intervention, Goal-focused Emotion-Regulation Therapy (GET), this trial is a randomized-controlled biobehavioral pilot trial of GET versus a time-and attention matched control (Instrumental Supportive Listening; ISL) in Latino/Hispanic young adult cancer survivors. Outcomes include improved distress symptoms, emotion regulation, goal navigation skills, and changes in stress-sensitive biomarkers.
Participants will be randomized to receive six sessions of GET or ISL delivered over eight weeks. In addition to indicators of intervention feasibility, the investigators will measure primary and secondary psychological outcomes prior to (T0), immediately after (T1), and twelve weeks after intervention (T2). Additionally, identified biomarkers will be measured at baseline and at T1, and T2. conditions: Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: PARTICIPANT count: 100 type: ESTIMATED name: Goal-Focused Emotion-Regulation Therapy (GET) name: Individual Supportive Listening (ISL) measure: Change in Hospital Anxiety and Depression Scale (HADS) measure: Change in Systemic Pro-inflammatory Cytokine Levels (IL-6, IL-1ra, C-reactive Protein (CRP), sTNFαRII) measure: Change in Salivary Diurnal Cortisol Slope and Daily Output measure: Change in Functional Assessment of Chronic Illness Therapy - Spiritual Well-Being (FACIT-Sp) Subscale Score measure: Change in Career Thoughts Inventory (CTI) Global Score measure: Change in Emotion Regulation Questionnaire (ERQ) Scale Scores measure: Change in Cancer Assessment for Young Adults (CAYA-T) - Goal Navigation Score measure: Change in Emotional Approach Coping Questionnaire (EAC) Scale Scores sex: MALE minimumAge: 18 Years maximumAge: 39 Years stdAges: ADULT hasResults: False
nctId: NCT06338462 id: 2000034128 id: R21AI174129 type: NIH link: https://reporter.nih.gov/quickSearch/R21AI174129 briefTitle: Cali Sin Tos Aim 2 overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-05 date: 2024-03-29 date: 2024-03-29 name: Yale University class: OTHER name: National Institute of Allergy and Infectious Diseases (NIAID) briefSummary: The overall objective of this Aim is to design and iteratively adapt a home-based, mHealth- and oral testing facilitated strategy for implementing tuberculosis (TB) contact tracing in Cali, Colombia. Investigators will employ an iterative, community-engaged, participatory co-design process to optimize the feasibility, acceptability, usability, and appropriateness of the mobile health (mHealth) and oral testing strategy, in preparation for a future, appropriately powered implementation-effectiveness trial.
This protocol includes the baseline contact tracing protocol and the procedures for determining adaptations to the mHealth strategy (i.e., nominal group technique). conditions: Tuberculosis studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: target sample size is an anticipated 120 index persons with TB enrolled over three design cycles primaryPurpose: PREVENTION masking: NONE count: 120 type: ESTIMATED name: Chatbot name: Oral testing measure: Implementation of the mHealth strategy to assess feasibility. measure: Oral specimen collection to assess feasibility. sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Centro Internacional de Entrenamiento e Investigaciones Medicas (CIDIEM) city: Cali country: Colombia lat: 3.43722 lon: -76.5225 hasResults: False
nctId: NCT06338449 id: XZMU-2022-ZK068 briefTitle: The Impact of Different Exercise Modes on Bile Acid Levels and Liver Function in Patients With Non-alcoholic Fatty Liver Disease overallStatus: COMPLETED date: 2022-10-13 date: 2022-12-20 date: 2022-12-31 date: 2024-03-29 date: 2024-04-02 name: Xuzhou Medical University class: OTHER briefSummary: The purpose of this clinical trial is to investigate which exercise regimen is more effective in improving non-alcoholic fatty liver disease (NAFLD) in a young population. The primary questions it aims to answer are:
Participants were randomly (Using an electronic random number generator) divided into four groups: control group (Control), aerobic training group (AT), resistance training group (RT), and combined aerobic and resistance training group (AT + RT), with each group consisting of 10 individuals, totaling 40 participants. All participants were young adults aged between 18 and 21 years old. primaryPurpose: TREATMENT masking: SINGLE maskingDescription: After the data is obtained, the person analyzing the data will not know the specific grouping and participant information. The groups will be replaced by Group A, B, C, D, and the participants will be indicated by their IDs. whoMasked: OUTCOMES_ASSESSOR count: 40 type: ACTUAL name: Aerobic training (AT) name: Resistance training (RT) name: Combined aerobic and resistance training (AT + RT) measure: Changes in body weight compared to baseline at 8 weeks measure: Changes in Body Mass Index compared to baseline at 8 weeks measure: Changes in total cholesterol compared to baseline at 8 weeks measure: Changes in triglycerides compared to baseline at 8 weeks measure: Changes in high-density lipoprotein compared to baseline at 8 weeks measure: Changes in low-density lipoprotein compared to baseline at 8 weeks measure: Changes in alanine aminotransferase compared to baseline at 8 weeks measure: Changes in aspartate aminotransferase compared to baseline at 8 weeks measure: Changes in alkaline phosphatase compared to baseline at 8 weeks measure: Changes in gamma-glutamyl transferase compared to baseline at 8 weeks measure: Changes in direct bilirubin compared to baseline at 8 weeks measure: Changes in total bile acids compared to baseline at 8 weeks measure: Changes in adenosine deaminase compared to baseline at 8 weeks measure: Changes in percentage of body fat compared to baseline at 8 weeks measure: Changes in waist-to-hip ratio compared to baseline at 8 weeks measure: Changes in blood glucose compared to baseline at 8 weeks measure: Changes in the level of insulin compared to baseline at 8 weeks measure: Changes in albumin compared to baseline at 8 weeks measure: Changes in C-reactive protein compared to baseline at 8 weeks measure: Changes in other subtypes of bile acids compared to baseline at 8 weeks sex: ALL minimumAge: 18 Years maximumAge: 23 Years stdAges: ADULT facility: Outdoor track and field facility of Xuzhou Medical University city: Xuzhou state: Jiangsu zip: 221000 country: China lat: 34.18045 lon: 117.15707 hasResults: False
nctId: NCT06338436 id: VAR-2022-05 briefTitle: Varian ProBeam Proton Therapy System China Clinical Trial (Guangzhou) overallStatus: COMPLETED date: 2022-12-21 date: 2023-09-26 date: 2023-11-13 date: 2024-03-29 date: 2024-04-02 name: Varian, a Siemens Healthineers Company class: INDUSTRY briefSummary: This study is prospective, single-center, single-arm objective performance criteria.
This trial will be conducted with a total of 47 subjects enrolled. All of subjects will be treated with radiation therapy using the medical device Varian ProBeam Proton Therapy System (ProBeam), aim to compare the data with objective performance criteria (OPC) to evaluate the effectiveness and safety of ProBeam radiotherapy system for oncology patients, providing a clinical basis for the medical device registration. conditions: Tumor, Solid studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: a clinical study of prospective, single-arm objective performance criteria primaryPurpose: TREATMENT masking: NONE count: 47 type: ACTUAL name: Proton Radiation Therapy System (ProBeam) measure: Effectiveness evaluation: Local tumor control rate 90 days after the proton radiation treatment completion measure: Safety evaluation: Incidence of Acute radiation injury measure: Safety evaluation: Incidence of Adverse Events based on CTCAE 5.0 criteria sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University city: Guangzhou state: Guangdong country: China lat: 23.11667 lon: 113.25 hasResults: False
nctId: NCT06338423 id: JagiellonianU-08 briefTitle: Use of a Vacuum Mattress During Laparoscopic Sleeve Gastrectomy to Reduce the Concentration of Rhabdomyolysis Markers and Acute Renal Failure overallStatus: COMPLETED date: 2015-01-01 date: 2022-12-31 date: 2022-12-31 date: 2024-03-29 date: 2024-03-29 name: Jagiellonian University class: OTHER briefSummary: This prospective clinical trial aimed to assess the usefulness of the usage of a vacuum mattress during laparoscopic sleeve gastrectomy (LSG) in the reduction of levels of rhabdomyolysis markers (myoglobin, creatine kinase, creatinine) and incidence of RML and AKI in the postoperative period.
Participants Patients aged ≥18 were qualified for LSG due to obesity and divided The first group (Vacuum Mattress group) are those laid on vacuum mattresses during the surgery. The control group consisted of patients for whom a standard operating mattress was used during the surgery. Patients with preoperative chronic renal failure were excluded from the study. Other exclusion criteria were perioperative complications which required postoperative hospitalization at the Intensive Care Unit and Compliance with Enhanced Recovery After Bariatric Surgery (ERABS) Protocol \< 85%.
Procedures and perioperative care All patients underwent LSG. Patients were operated in the beach chair position. In the study group, the patient was laid on vacuum mattresses during the surgery. In the case of control group patients, a standard operating mattress was used during the surgery. Perioperative care for all patients was in accordance with the ERABS protocol adopted in our center\[\]. Blood samples were collected on the first postoperative to measure RML markers (myoglobin, creatine kinase, creatinine). Symptoms of RML, AKI, and other complications were monitored for 30 days after surgery.
Secondary endpoints is the concentrations of RML markers (myoglobin, creatine kinase, creatinine) on the first postoperative day conditions: Rhabdomyolysis conditions: Acute Kidney Injury conditions: Bariatric Surgery Candidate studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 1184 type: ACTUAL name: vacuum mattress name: Standard Mattress measure: Incidance of Rhabdomyolisis(RML) And/OR Acute Kidnay Injury (AKI) measure: Concentration of myoglobin marker measure: Concentration of creatine kinase marker measure: Concentration of creatinine marker sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Jagiellonian University Mecical Collage city: Kraków state: Malopolskie zip: 31-501 country: Poland lat: 50.06143 lon: 19.93658 hasResults: False
nctId: NCT06338410 id: UHS/Education/126-24/131 briefTitle: Effect of Kangaroo Mother Care on Oxidative Stress and Bonding acronym: KMC overallStatus: COMPLETED date: 2023-08-01 date: 2024-03-20 date: 2024-03-20 date: 2024-03-29 date: 2024-04-01 name: University of Health Sciences Lahore class: OTHER name: Services Hospital, Lahore briefSummary: The goal of this clinical trial is to learn if Kangaroo Mother care can have effect on oxidative stress in premature neonates. It will also learn about the bonding between mother and her premature infant. The main questions it aims to answer are:
* Mother-infant bonding scale will be filled by mothers of enrolled premature infants before and after kangaroo mother care and conventional incubator care conditions: Kangaroo Mother Care conditions: Oxidative Stress studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 40 type: ACTUAL name: Kangaroo Mother Care measure: biomarker of Oxidative Stress (Allantoin) in urine sample of premature infants measure: Mother- Infant Bonding sex: ALL minimumAge: 3 Days maximumAge: 3 Days stdAges: CHILD facility: Services Hospital, Lahore city: Lahore state: Punjab zip: 54000 country: Pakistan lat: 31.558 lon: 74.35071 hasResults: False
nctId: NCT06338397 id: 2023_0455 briefTitle: Social & Affective Cognition in Alzheimer's Disease & Associated Disorders acronym: SOCIALIZE overallStatus: NOT_YET_RECRUITING date: 2024-05-02 date: 2027-05-02 date: 2027-05-02 date: 2024-03-29 date: 2024-03-29 name: University Hospital, Lille class: OTHER name: France Alzheimer briefSummary: Recent studies have shown that individual neuropsychological scores of patients with Alzheimer's disease and Associated Disorders (ADAD) are only poorly correlated to their behavioral difficulties, such as disinhibition, apathy, social decision-making or vulnerability. Recently, social \& affective cognitive disorders have been highlighted as potential cause of social behavioral abnormalities. However, no previous studies have assessed the specific relationship between social \& affective cognition \& social behavior in ADAD. Our pilot study aims to explore the correlations between core and extended social \& affective cognitive processes and social behavior as observed during the neuropsychological examination, as well as to explore the common brain regions involved in those domains. conditions: Alzheimer's Disease conditions: Frontotemporal Degeneration (Semantic & Behavioral Variants) studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: OTHER masking: NONE count: 120 type: ESTIMATED name: SCANN measure: Correlation coefficient between the mini Social cognition & Emotional Assessment - mini-SEA - total score and the Social Behavior Observer Checklist - SBOC - score in all participants. measure: Correlation coefficients between the mini Social cognition & Emotional Assessment - mini-SEA - sub scores and the neuropsychological assessment (as measured by the Social Behavior Observer Checklist - SBOC - score in all participants. measure: Correlation coefficient between the SBOC score with MRI markers in all participants measure: Correlation coefficient between mini-SEA sub scores & MRI markers in all participants. measure: Correlation coefficients between mini-SEA sub scores with the SOCIAL50, CBI, ZBS, CSDC, SVS scales in each ADAD and controls groups. measure: Correlation coefficients between SCANN sub-scores and the SBOC, SOCIAL50, CBI, ZBS, CSDC, SVS scales in each ADAD and controls groups. sex: ALL minimumAge: 40 Years maximumAge: 85 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06338384 id: 44735129 briefTitle: Examining Engagement Trends Among Participants in Peripheral Neuropathy Clinical Research overallStatus: NOT_YET_RECRUITING date: 2025-04 date: 2026-04 date: 2027-04 date: 2024-03-29 date: 2024-03-29 name: Power Life Sciences Inc. class: INDUSTRY briefSummary: This trial aims to uncover the factors driving patient decisions regarding enrollment, withdrawal, or re-engagement in peripheral neuropathy clinical trials. Understanding these factors will significantly improve the relevance and effectiveness of future research endeavors.
Ultimately, this trial endeavors to deepen our understanding of the factors impacting peripheral neuropathy clinical trial participation. Enhancing participation rates could accelerate the development of innovative treatments for this debilitating condition. conditions: Peripheral Neuropathy studyType: OBSERVATIONAL observationalModel: CASE_CROSSOVER timePerspective: PROSPECTIVE count: 500 type: ESTIMATED measure: Number of peripheral neuropathy patients who decide to enroll in a clinical research measure: Rate of peripheral neuropathy patients who remain in clinical trial to trial completion sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Power Life Sciences city: San Francisco state: California zip: 94107 country: United States name: Michael B Gill role: CONTACT phone: 415-900-4227 email: https://www.withpower.com/contact-us@withpower.com lat: 37.77493 lon: -122.41942 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2024-03-22 uploadDate: 2024-03-22T09:04 filename: ICF_000.pdf size: 67357 hasResults: False
nctId: NCT06338371 id: IZTU-TEKBAŞ-001 briefTitle: Effect of Pelvic Floor Muscle Exercise on Sexual Function overallStatus: COMPLETED date: 2021-11-01 date: 2022-04-06 date: 2022-05-06 date: 2024-03-29 date: 2024-03-29 name: Serap Tekbas class: OTHER briefSummary: The goal of this evaluate the effect of pelvic floor muscle exercises on sexual function in women of reproductive age. A randomized controlled trial was conducted in a sample of women of reproductive age, 77 women were randomly assigned to control (n=39) and training (n=38) groups. A form including questions regarding socio-demographic characteristics and the Female Sexual Function Index was applied to all women included in the study. Pelvic floor exercise training was given to the women in the training group and the Female Sexual Function Index was applied to both groups in the 1st, 2nd, and 3rd months. The differences between those who received and those who did not receive training and the effects of regular pelvic exercise on sexual function were evaluated by month.
H2: Sexual function scores are higher for those who regularly exercise their pelvic floor muscles for at least two months conditions: Pelvic Floor Muscle Weakness conditions: Sexuality studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: SINGLE whoMasked: PARTICIPANT count: 77 type: ACTUAL name: Pelvic Floor exercise training measure: Determining Number of Participants measure: Initial scale application measure: Distribution of participants into groups measure: Providing pelvic floor exercise for training group measure: Female Sexual Function Index measure: Female Sexual Function Index measure: Female Sexual Function Index sex: FEMALE minimumAge: 18 Years maximumAge: 49 Years stdAges: ADULT facility: Izmir Tinaztepe University city: İzmir state: Buca zip: 35400 country: Turkey lat: 38.41273 lon: 27.13838 hasResults: False
nctId: NCT06338358 id: 44519568 briefTitle: Understanding Participation Habits Among Plaque Psoriasis Patients overallStatus: NOT_YET_RECRUITING date: 2025-04 date: 2026-04 date: 2027-04 date: 2024-03-29 date: 2024-03-29 name: Power Life Sciences Inc. class: INDUSTRY briefSummary: The study intends to investigate the personal experiences of plaque psoriasis patients who take part in a separate clinical study including a specific medication intervention. The major focus will be on closely following individuals' rates of trial completion and withdrawal.
The data collected from this study will help improve future outcomes for all plaque psoriasis as well as those in under-represented demographic groups. conditions: Plaque Psoriasis studyType: OBSERVATIONAL observationalModel: CASE_CROSSOVER timePerspective: PROSPECTIVE count: 500 type: ESTIMATED measure: Rate of patients who decide to enroll in a plaque psoriasis clinical research. measure: Number of plaque psoriasis study participants who remain in clinical study until completion. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Power Life Sciences city: San Francisco state: California zip: 94107 country: United States name: Michael B Gill role: CONTACT phone: 415-900-4227 email: https://www.withpower.com/contact-us@withpower.com lat: 37.77493 lon: -122.41942 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2024-03-22 uploadDate: 2024-03-22T09:21 filename: ICF_000.pdf size: 67831 hasResults: False
nctId: NCT06338345 id: 38RC23.0222 briefTitle: Pharmacokinetics and Modelling of Beta-Lactam in ECMO-VA Patients acronym: KAMELOT overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2027-09-01 date: 2028-09-01 date: 2024-03-29 date: 2024-03-29 name: University Hospital, Grenoble class: OTHER briefSummary: The use of antibiotic therapy is common in intensive care units and primarily involves beta-lactams. Its optimal implementation is made difficult by the pharmacokinetic changes inherent in critically ill patients.
Despite the current recommendations from the French Society of Anesthesiology and Intensive Care (SFAR) and the French Society of Pharmacology and Therapeutics (SFPT), there are no recommendations on prescription modalities for patients under veno-arterial extracorporeal membrane oxygenation (VA-ECMO). The use of antibiotic therapy is common in VA-ECMO patients and their pharmacokinetic variability factors are then exacerbated.