hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06273579 id: 2010-270, NEU-09-042-Trial 5 briefTitle: Efficiency of Verbal Intelligent Tutor Instruction in Neurosurgical Simulation overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-10 date: 2024-12 date: 2024-02-22 date: 2024-03-05 name: McGill University class: OTHER briefSummary: At the Neurosurgical Simulation and Artificial Intelligence Learning Centre, we seek to provide surgical trainees with innovative technologies that allow them to improve their surgical technical skills in risk-free environments, potentially improving patient operative outcomes. The Intelligent Continuous Expertise Monitoring System (ICEMS), a deep learning application that assesses and trains neurosurgical technical skill and provides continuous intraoperative feedback, is one such technology that may improve surgical education.
In this randomized controlled trial, medical students from four Quebec universities will be blinded and randomized to one of three groups (one control and two experimental). Group 1 (control) will be provided with verbal AI tutor feedback based on the ICEMS error detection. Group 2 will be tutored by a human instructor who will receive ICEMS error data and deliver verbal instruction identical to that which the AI tutor delivers. Group 3 will be tutored by a human instructor who will be provided with ICEMS data but may deliver feedback as they feel is appropriate to correct the error.
The aim of this study is to determine how the method of delivery of verbal surgical error instruction influences trainee response to instruction and overall surgical performance. Evaluating trainee responses to AI instructor verbal feedback as compared to feedback from human instructors will allow for further development, testing, and optimization of the ICEMS and other AI tutoring systems. conditions: Surgical Education studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomized Controlled Trial primaryPurpose: HEALTH_SERVICES_RESEARCH masking: DOUBLE maskingDescription: Double (Participant, Expert Instructor)
Both study participants and expert instructors are unaware of the intervention (varying the method of delivery of verbal error instruction). Moreover, when rating performance in the realistic scenario using the OSATS, experts are unaware of which group any given trainee is part of. whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 78 type: ESTIMATED name: Experimental Group - Verbal expert instructor feedback in AI's words name: Experimental Group - Verbal expert instructor feedback in expert's own words measure: Response to instruction measure: Average Intelligent Continuous Expertise Monitoring System (ICEMS) expertise score measure: Objective Structured Assessment of Technical Skills (OSATS) global rating measure: Difference in the strength of emotions elicited measure: Difference in cognitive load sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Neurosurgical Simulation and Artificial Intelligence Learning Centre city: Montréal state: Quebec zip: H2X 4B3 country: Canada name: Rolando F Del Maestro, MD, PhD role: CONTACT phone: (519) 708-0346 email: rolando.del_maestro@mcgill.ca name: Bianca Giglio, BSc role: CONTACT phone: (514) 802-1608 email: bianca.giglio@mail.mcgill.ca lat: 45.50884 lon: -73.58781 hasResults: False
nctId: NCT06273566 id: 20230202 briefTitle: French Validation of the AdT-Physio Scale acronym: Trans-AdT overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-12-31 date: 2025-07-31 date: 2024-02-22 date: 2024-03-19 name: Pole Sante Grace de Dieu class: OTHER briefSummary: The goal of this observational study is to translate and validate the Adt-Physio scale in French, and to validate on a large number of patients the French translation of the Adt-Physio scale as a tool for evaluating adherence and perception of the intervention of a physiotherapist in patients with cystic fibrosis.
participants will have to answer the French trans-AdT scale, the Brief Cope and GSES questionnaire. conditions: Cystic Fibrosis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 121 type: ESTIMATED name: Questionnaire measure: AdT-Physio scale (Adherence to Treatment of Physiotherapy scale) sex: ALL minimumAge: 18 Years maximumAge: 100 Years stdAges: ADULT stdAges: OLDER_ADULT facility: PSLA GDD city: Caen zip: 14000 country: France lat: 49.18585 lon: -0.35912 hasResults: False
nctId: NCT06273553 id: RG002-A1201 briefTitle: A Study in Subjects With Human Papillomavirus 16 or 18 Associated Cervical Intraepithelial Neoplasia Grade 2 or 3 overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-10 date: 2027-12 date: 2024-02-22 date: 2024-02-22 name: RinuaGene Biotechnology Co., Ltd. class: INDUSTRY briefSummary: The purpose of this study is to to evaluate the safety, tolerability, immunogenicity, and efficacy of RG002 Injection in subjects with HPV16/18 associated Cervical Intraepithelial Neoplasia Grade 2 or 3(CIN2/3). conditions: Human Papillomavirus Associated Intraepithelial Neoplasia conditions: Cervical Intraepithelial Neoplasia Grade 2/3 conditions: Human Papillomavirus Type 16 Infection conditions: Human Papillomavirus Type 18 Infection studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 39 type: ESTIMATED name: RG002 injection measure: Part A: Safety and Tolerability of RG002 Injection, measured by the incidence of adverse events measure: Part A: Maximum tolerated dose (MTD) and/or RP2D of RG002 Injection measure: Part B: Primary efficacy of RG002 Injection, measured by the proportion of subjects with histopathological regression measure: Part A: Preliminary efficacy of RG002 Injection,measured by proportion of subjects with histopathological regression measure: Part A: Preliminary efficacy of RG002 Injection,measured by proportion of subjects with clearance of HPV16/18 measure: Part A: Preliminary efficacy of RG002 Injection,measured by proportion of subjects with histopathological regression and clearance of HPV16/18 measure: Part A and B: Immunogenicity of RG002 Injection,measured by the level of cellular immune response measure: Part A and B: Immunogenicity of RG002 Injection,measured by the proportion of T lymphocytes measure: Part A and B: Immunogenicity of RG002 Injection,measured by the expression of cytokines in serum measure: Part A and B: Immunogenicity of RG002 Injection,measured by the serum levels of anti-HPV16 and anti-HPV18 IgG antibodies. measure: Part A and B: Exposure level of RG002 Injection, measured by mRNA measure: Part A and B: Exposure level of RG002 Injection, measured by cationic lipids measure: Part A and B: Anti-drug antibody (ADA) to polyethylene glycol (PEG) of RG002 injection, measured by the serum titer of anti-PEG IgG and anti-PEG IgM measure: Part B: Secondary efficacy, measured by proportion of subjects with histopathological regression measure: Part B: Secondary efficacy, measured by proportion of subjects with clearance of HPV16/18 measure: Part B: Secondary efficacy, measured by proportion of subjects with histopathological regression and clearance of HPV16/18 measure: Part B: Safety and tolerability of RG002 Injection, measured by the incidence of adverse events measure: Part B: Optionally assess the biomarker of RG002 Injection, measured by the level of potential biomarkers and the level of infiltrating T cells and myeloid cells in the lesions. sex: FEMALE minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT hasResults: False
nctId: NCT06273540 id: STA-P7-C001 briefTitle: Phase1, STP7 Cocaine Drug-Drug Interaction Study overallStatus: RECRUITING date: 2024-04-15 date: 2024-09-30 date: 2024-09-30 date: 2024-02-22 date: 2024-04-19 name: Stalicla SA class: INDUSTRY name: National Institute on Drug Abuse (NIDA) briefSummary: This is a double-blind, placebo-controlled, parallel group study to compare the effects of STP7 (mavoglurant) vs placebo control on i.v. cocaine's physiological and subjective effects in non-treatment seeking, cocaine-experienced males or females participants between 18 and 59 years of age.
nctId: NCT06273527 id: 808681 briefTitle: Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33) overallStatus: NOT_YET_RECRUITING date: 2024-11 date: 2027-06 date: 2027-06 date: 2024-02-22 date: 2024-02-22 name: University of California, San Diego class: OTHER briefSummary: The proposed project aims to test the cognitive and neural effects of a cognitive training in a sample of individuals seeking treatment for anxiety, depression, or traumatic stress symptoms. Participants will be randomly assigned to one of two groups. Group 1 will receive a computer-based program that is designed as a cognitive training intervention and Group 2 will receive a similar computer-based exercise that researchers think will be less effective in training thinking skills (also known as a control or sham condition). Participants will be compared on cognitive performance and brain response during cognitive tasks from baseline to post-treatment. conditions: Anxiety Disorders conditions: Depression conditions: Post Traumatic Stress Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 128 type: ESTIMATED name: COGENT name: Sham Program measure: Change in cognitive performance measure: Reading Span Blood Oxygen Level Dependent (BOLD) Response measure: Neuropsychological Performance measure: Repetitive Negative Thinking (RNT) measure: Disability measure: Suicide Cognitions measure: Mood and Emotions measure: Self-reported attention measure: Anxiety Symptoms measure: Symptoms of Depression measure: PTSD Symptoms sex: ALL minimumAge: 21 Years maximumAge: 55 Years stdAges: ADULT facility: UC San Diego city: San Diego state: California zip: 92037 country: United States name: Edith Jimenez role: CONTACT phone: 858-822-1470 email: e7jimenez@health.ucsd.edu name: Nathalie Dugas role: CONTACT phone: 858-534-2148 email: ndugas@health.ucsd.edu lat: 32.71533 lon: -117.15726 hasResults: False
nctId: NCT06273514 id: TECAR and DN intervention briefTitle: Comparison the Effects of TECAR With Dry Needling in the Treatment of Myofascial Trigger Points overallStatus: COMPLETED date: 2020-12-01 date: 2022-12-31 date: 2022-12-31 date: 2024-02-22 date: 2024-02-22 name: Medical University of Silesia class: OTHER briefSummary: The aim of the study is to assess the effectiveness of dry needling (DN) and capacitive and resistive transfer of energy (TECAR) therapy in the treatment of myofascial trigger points (MTrPs) as well comparison of their efficacy.
It is estimated that the presence of trigger points is the main cause of pain in 30-85% of patients visiting primary health care facilities and pain management clinics. The presence of trigger points may significantly affect the patient's functional status and daily functioning. Recently, diagnostic criteria and methods of treating trigger points have evolved significantly. However, the usefulness of different imaging methods in the diagnosis of trigger points has not yet been established. Despite numerous studies, the long-term effectiveness of the dry needling method is still unknown. Furthermore, there is no available research on the short- and long-term effectiveness of capacitive and resistive energy transfer therapy in the treatment of trigger points.
In order to determine the immediate effects of capacitive and resistive energy transfer therapy and dry needling techniques, measurements of muscle strength, the intensity of pain in the upper trapezius muscle and neck range of motion will be performed before and after each therapeutic session (2 session in 2 weeks are planed). In turn, to determine the long-term effects of capacitive and resistive energy transfer therapy and dry needling, the next above-mentioned measurements will be performed four weeks after the end of first therapy. conditions: Myofascial Pain Syndrome of Neck conditions: Myofascial Trigger Point Syndrome conditions: Myofascial Trigger Point Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 22 type: ACTUAL name: TECAR name: Dry needling measure: Pain - Pressure pain threshold (PPT) measure: Pain - numerical rating scale (NRS) measure: Muscle strength measure: Cervical spine range of motion (ROM) sex: MALE minimumAge: 25 Years maximumAge: 45 Years stdAges: ADULT facility: Medical fit city: Ruda Śląska state: Śląsk zip: 41-717 country: Poland lat: 50.2584 lon: 18.85632 hasResults: False
nctId: NCT06273501 id: D-NR 2022-02876-01 briefTitle: MRI and Magnetometer-guided Sentinel Lymph Node Detection in Vulvar Cancer acronym: POSVUC overallStatus: ENROLLING_BY_INVITATION date: 2022-03-24 date: 2024-12-01 date: 2024-12-31 date: 2024-02-22 date: 2024-02-22 name: Sahlgrenska University Hospital, Sweden class: OTHER briefSummary: The aim of the feasibility study is to evaluate whether SPIO-MRI and a magnetometer could be a potential substitute to the routine dual technique in pre-and intraoperative SLN localization. Secondary, to explore if SPIO-MRI could predict lymph node status in comparison to histopathological analysis. conditions: Vulvar Cancer conditions: Lymph Node Metastasis studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 20 type: ESTIMATED name: Magtrace measure: Sentinel lymph node identification sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Obstetrics and gynecology city: Gothenburg zip: 41345 country: Sweden lat: 57.70716 lon: 11.96679 hasResults: False
nctId: NCT06273488 id: EXZL20240002 briefTitle: The Role of Auricular Point Diagnosis and Treatment in ERAS During TKA overallStatus: RECRUITING date: 2024-03-23 date: 2024-11-01 date: 2024-12-01 date: 2024-02-22 date: 2024-04-08 name: Peking Union Medical College class: OTHER briefSummary: To further improve the surgical outcomes of patients undergoing total knee arthroplasty (TKA). This study aims to use ear acupoint therapy to address the following clinical issues: 1 The degree of postoperative inflammation and edema in the patient; 2. Patient pain; 3. Patient functional recovery. 4. Surgical scar repair for patients; 5. Patient perioperative anxiety and postoperative satisfaction. Exploring the safety and effectiveness of ear acupoint therapy in the postoperative application of TKA, leveraging the advantages of suitable traditional Chinese medicine techniques in simplicity, convenience, effectiveness, and cost-effectiveness, and further improving the ERAS Chinese and Western medicine collaborative plan for TKA. conditions: Auriculotherapy conditions: Arthroplasty, Replacement, Knee conditions: Enhanced Recovery After Surgery studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 86 type: ESTIMATED name: Auriculotherapy measure: Range of motion(ROM) measure: Visual Analogue Pain Scale (VAS) measure: Self-Assessment Survey for Anxiety（SAS） measure: Acupoint electrical measurement value(AE) measure: Vancouver Scar Assessment Scale（VSS） measure: Dosage of painkillers measure: Hospital stay measure: HSS knee joint scoring measure: Thigh circumference(knee joint circumference) measure: Kine siphobia (TSK) score measure: C-reactive protein (CRP) measure: Erythrocyte Sedimentation Rate(ESR) measure: Postoperative satisfaction measure: Expenses during hospitalization measure: Demand rate and satisfaction rate of auricular point diagnosis and treatment measure: Adverse events related to auricular acupuncture diagnosis and treatment measure: Affected limb drainage volume measure: Preoperative Anxiety Scale (PAS-7) score measure: Total number of pain pump uses (presses) sex: ALL minimumAge: 50 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Peking Union Medical College Hospital status: RECRUITING city: Beijing state: Beijing zip: 100000 country: China name: qindong Mi role: CONTACT phone: 8615871784551 email: mqd2022ky@163.com lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06273475 id: OUH RoboRehab briefTitle: Robot-Assisted Training Versus Standard Training in Ischemic Stroke overallStatus: RECRUITING date: 2024-05-01 date: 2025-03-01 date: 2027-02-01 date: 2024-02-22 date: 2024-04-18 name: Odense University Hospital class: OTHER name: University of Southern Denmark name: Rigshospitalet, Denmark name: Herlev and Gentofte Hospital name: Stanford University name: Sygehus Lillebaelt name: Danish Association of the Physically Disabled briefSummary: The aim of this randomised controlled trial (RCT) nested in a prospective cohort, is to investigate the superior effect of late-phase robot-assisted versus standard training on motor function, physical function, fatigue, and quality of life in a moderately-to-severely impaired chronic stroke population following subacute rehabilitation.
Robot-assisted training has a superior effect on motor function (Fugl-Meyer Lower Extremity Assessment; primary outcome), physical function, fatigue, and quality of life in moderately-to-severely impaired chronic stroke-affected individuals in comparison to standard training. conditions: Stroke conditions: Ischemic Stroke studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Multicentre randomised (1:1) parallel-group intervention study with assessor-blinding. primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Data will be analysed by the PhD student blinded towards group allocation. The test leader responsible for RCT outcome assessment will be blinded towards group allocation. whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: Robot-assisted Training name: Standard Training measure: Fugl-Meyer Lower Extremity Assessment of Motor Function measure: Modified Rankin Scale Score (between-group change) measure: Functional Ambulation Category (between-group change) measure: Berg Balance Scale (between-group change) measure: Barthel-100 Index (between-group change) measure: Global Rating of Change (between-group change) measure: International Physical Activity Questionnaire - Short Form (between-group change) measure: Fatigue Severity Scale 7 (between-group change) measure: EQ-5D-5L Quality of Life (between-group change) measure: Hand-grip strength (between-group change) measure: Gait speed (between-group change) measure: Contractile Muscle Power (between-group change) measure: Modified Sit-to-Stand Test (between-group change) measure: Blood Biomarkers (between-group change) measure: Modified Ashworth Scale (between-group change). measure: Oxford Cognitive Screen (between-group change) measure: Montreal Cognitive Assessment (between-group change) measure: Major Depression Inventory (between-group change) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Rigshospitalet and Herlev Gentofte Hospital status: NOT_YET_RECRUITING city: Copenhagen country: Denmark name: Jon Skovgaard Jensen, Ph.d.-student role: CONTACT email: jskovgaard@health.sdu.dk name: Christina Rostrup Kruuse, Professor, MD, PhD, DMSc role: PRINCIPAL_INVESTIGATOR lat: 55.67594 lon: 12.56553 facility: Odense University Hospital status: RECRUITING city: Odense country: Denmark name: Jon Skovgaard Jensen, Ph.d.-student role: CONTACT email: jskovgaard@health.sdu.dk name: Anders Holsgaard-Larsen, Professor role: PRINCIPAL_INVESTIGATOR lat: 55.39594 lon: 10.38831 hasResults: False
nctId: NCT06273462 id: NMCSD.2024.0006 briefTitle: Palmitoylethanolamide for Chronic Inflammatory Pain Conditions overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-05-30 date: 2024-02-22 date: 2024-02-22 name: Navy Medical Center San Diego class: FED briefSummary: The goal of this clinical trial is to evaluate if a supplement called palmitoylethanolamide (PEA) is effective in reducing the pain in patients with chronic inflammatory pain conditions. The main question the trial aims to answer is if PEA works better at treating a patients pain and improving their function better than a placebo.
Participants will be divided into two equal groups and asked to take either PEA or a placebo for 8 weeks. conditions: Chronic Pain studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Prospective Randomize Double Blind Placebo Controlled study comparing the supplement palmitoylethanolamide (PEA) to a visually identical placebo primaryPurpose: TREATMENT masking: QUADRUPLE maskingDescription: Double Blinded, patients will receive visually identical capsules from research pharmacist with study label indicating PEA vs Placebo whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 80 type: ESTIMATED name: Palmitoylethanolamide 600mg twice a day name: placebo measure: Pain Level measure: Pain interference and function measure: Pain Catastrophizing Scale (PCS) measure: Patient Reported Outcome Measurement Information System (PROMIS) (Pain interference, Social satisfaction; Physical function) sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Naval Medical Center San Diego city: San Diego state: California zip: 92118 country: United States name: Naval Medical Center Institutional Review Board role: CONTACT phone: 619-532-9927 email: kristina.m.umali.civ@health.mil name: Brian McLean COL, USA MC, MD role: PRINCIPAL_INVESTIGATOR lat: 32.71533 lon: -117.15726 hasResults: False
nctId: NCT06273449 id: 385/2023 briefTitle: A Smart Digital Workflow Towards High Precision and Through-Put Production for Removable Partial Dentures overallStatus: RECRUITING date: 2022-12-29 date: 2024-08-30 date: 2024-08-30 date: 2024-02-22 date: 2024-02-22 name: National Dental Centre, Singapore class: OTHER name: National Medical Research Council (NMRC), Singapore briefSummary: Tooth loss is a major chronic problem in dentistry and edentulous elderly endures poorer quality of life worldwide. Removable partial dentures (RPDs) are the most widely accepted and cost-effective treatment for patients to restore oral functions. RPDs contain three components including the metal framework, denture base and acrylic teeth. Conventionally, RPD fabrication involves tedious clinical and dental laboratory procedures and is time consuming, labour-intensive, and often imprecise, therefore incapable of meeting the growing demands of RPD by an ageing population. The challenges to achieve a high quality and high-throughput RPD service lie in three aspects: 1) accuracy in capturing oral profile; 2) immediate oral information analysis and device design, and 3) automation in production. conditions: Partial-edentulism studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: 1. Conventional: The Standard of Care (SOC) workflow, which will act as a baseline compared to the other 2 groups.