hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06351241 id: E.222840/280 briefTitle: Hemodynamic Effects of Steep Trendelenburg Position and Pneumoperitoneum overallStatus: COMPLETED date: 2022-11-29 date: 2023-04-14 date: 2023-04-14 date: 2024-04-08 date: 2024-04-08 name: Ege University class: OTHER briefSummary: BACKGROUND: The steep Trendelenburg position and pneumoperitoneum are used to improve surgical visibility in robot-assisted laparoscopic radical prostatectomy (RALRP). However, these procedures can lead to hemodynamic changes. This study aimed to investigate the effects of these interventions on the perfusion index (PI) and the Pleth variability index (PVI) in patients undergoing RALRP under general anesthesia.
METHODS: Fifty-three patients scheduled for RALRP underwent standard monitoring; PI and PVI values were monitored using a finger probe. PI, PVI, hemodynamic and respiratory parameters, and intraabdominal pressure were recorded before and after anesthesia induction, after adopting the Trendelenburg position, after pneumoperitoneum, after pneumoperitoneum and the Trendelenburg position, at 15 min, 30 min, in the supine position, after carbon dioxide (CO2) desufflation, and after extubation. conditions: Perfusion Index conditions: Pleth Variability Index studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 53 type: ACTUAL measure: Hemodynamic effects of steep trendelenburg position and pneumoperitoneum in urologic robotic surgery sex: MALE minimumAge: 25 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Nursen Karaca city: Bornova state: İzmir zip: 35040 country: Turkey lat: 38.47921 lon: 27.2399 hasResults: False
nctId: NCT06351228 id: 5720 briefTitle: Fertility-sparing in Early-stage Cervcial Cancer: The ETERNITY Project acronym: Eternity overallStatus: NOT_YET_RECRUITING date: 2024-03-30 date: 2024-12-31 date: 2024-12-31 date: 2024-04-08 date: 2024-04-08 name: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano class: OTHER briefSummary: The ETERNITY project is a retrospective analysis of outcomes of patients undergoing fertility-sparing treatment for cervcial cancer.
3. Evaluation of the impactof neoadjuvant chemotherapy in patients undergoing conservative surgery conditions: Cervical Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 400 type: ESTIMATED name: Conization plus nodal evaluation measure: oncological outcomes sex: FEMALE minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Fondazione IRCCS Istituto Nazionale dei Tumori di Milano city: Milano state: Lombardia zip: 20133 country: Italy lat: 45.46427 lon: 9.18951 hasResults: False
nctId: NCT06351215 id: APP-24-00554 briefTitle: PO Methadone Ortho Outpatient overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2024-12-01 date: 2024-12-15 date: 2024-04-08 date: 2024-04-08 name: Keck School of Medicine of USC class: OTHER briefSummary: The goal of this clinical trial is to learn if oral methadone given before surgery works to minimize post-operative pain and opioid usage. The main questions it aims to answer are:
Receive either oral methadone or a look-alike placebo before surgery Receive standard intraoperative and immediate post-operative pain control at the anesthesiologist's discretion Be asked about their pain levels in the recovery area Keep a diary of pain and opioid usage over the first 2 days after surgery conditions: Arthroscopic Knee Repair conditions: Arthroscopic Hip Repair studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 100 type: ESTIMATED name: Methadone group name: Placebo measure: Post-op opioid usage measure: Post-op Pain Score sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: USC Healthcare Consultation 3 city: Los Angeles state: California zip: 90033 country: United States name: Alexander Chen, M.D. role: CONTACT phone: 323-442-7400 email: painmed@usc.edu name: Abigail Song, B.S. role: SUB_INVESTIGATOR name: Benjamin Liu, M.D. role: SUB_INVESTIGATOR name: Paul Lee, M.D., M.S. role: SUB_INVESTIGATOR lat: 34.05223 lon: -118.24368 hasResults: False
nctId: NCT06351202 id: RBGP 2023 COLNE id: 2023-A02256-39 type: OTHER domain: ANSM briefTitle: Impact Assessment of Abdominal Massage on Feeding Tolerance of Preterms acronym: PREMABDO overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-02 date: 2026-06 date: 2024-04-08 date: 2024-04-10 name: University Hospital, Clermont-Ferrand class: OTHER briefSummary: Every year in France, 60,000 children are born prematurely (before 37 weeks of amenorrhea - WA), and present an immaturity of their various systems, in particular the digestive system. This can result in feeding intolerance, expressed by abdominal distension, regurgitation, irregular transit and abdominal discomfort. It can influence the length of hospitalization and lead to necrotising enterocolitis, a major complication.
The aim of the study is to assess the effectiveness of abdominal massage, over a period of 14 days, on the feeding tolerance of preterm infants (under 34 weeks of amenorrhea), defined by the achievement and maintenance of an ECAP score less than 4 during 3 days. conditions: Preterm Birth Complication conditions: Digestive System Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 120 type: ESTIMATED name: Abdominal massage measure: Clinical Abdominal assessment scale for Preterm infants score (ECAP score) measure: Variation of the ECAP score (Clinical Abdominal assessement scale for preterms score) between t0 minute and t10 minutes measure: Weight gain of preterm infants with feeding intolerance measure: Duration to reach the full ration measure: Duration of hospitalization in level 3 measure: 6-hour fasting windows measure: Incidence of occurrence of necrotizing enterocolitis measure: Evolution of digestive tolerance over time sex: ALL minimumAge: 3 Days maximumAge: 60 Days stdAges: CHILD facility: CHU clermont-ferrand city: Clermont-Ferrand country: France lat: 45.77966 lon: 3.08628 hasResults: False
nctId: NCT06351189 id: CIVI/2022/AD-01 briefTitle: NETTI Wheelchair: Does Dynamic Mode or Static Mode Affect the Sitting Position in Patients With Involuntary Movements ? acronym: DYNAMIC SYSTEM overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-06-01 date: 2026-08-01 date: 2024-04-08 date: 2024-04-08 name: Centre Hospitalier Universitaire de Nīmes class: OTHER briefSummary: This study compares two modes of the NETTI wheelchair (dynamic or sitting) for patients with hyperkinetic syndromes, to discover which mode is the most comfortable and best suited to these patients.
nctId: NCT06351176 id: 2024-6819 briefTitle: Impact of Glycemic Control on Skeletal Outcomes in Adults With Type 1 Diabetes acronym: DenSiFy cohort overallStatus: ENROLLING_BY_INVITATION date: 2023-07-04 date: 2024-12-22 date: 2025-08-29 date: 2024-04-08 date: 2024-04-08 name: CHU de Quebec-Universite Laval class: OTHER name: Diabetes Canada briefSummary: Background : Type 1 diabetes (T1D) is associated with an increased risk of fractures. The mechanisms accounting for this bone fragility are not yet fully understood. As T1D is often diagnosed in childhood or early adulthood, the lower bone mineral density (BMD) and deteriorated bone microarchitecture observed in T1D may reflect changes in the bone that occurred before or at the time of peak bone mass achievement. There is a lack of high-quality prospective studies to determine whether adults with T1D continue to lose BMD or deteriorate bone quality compared with controls. Moreover, while chronic hyperglycemia is a risk factor for fracture in T1D, it is unknown if better glycemic control affects bone outcomes.
nctId: NCT06351163 id: 1451_03/BVNTW-VNCSKTE briefTitle: Minimally Invasive Surgical Management for Pediatric Intussusception: A Retrospective Cohort Study overallStatus: COMPLETED date: 2016-01 date: 2020-12 date: 2024-03 date: 2024-04-08 date: 2024-04-08 name: National Children's Hospital, Vietnam class: OTHER name: Vinmec Research Institute of Stem Cell and Gene Technology briefSummary: Intussusception is the primary cause of intestinal obstruction in children aged 3 months to 5 years, leading to significant morbidity and mortality rates. Most cases involve the ileocolic region and can often be resolved through air enema, with a success rate of up to 95%. Surgical intervention becomes necessary if pneumatic reduction fails or is not recommended. Traditionally, manual reduction required a large incision on the right side of the abdomen. However, the advancement of minimally invasive techniques, such as the laparoscopic approach (LAP), has become increasingly popular for managing intussusception. LAP offers benefits such as reduced surgical trauma and shorter operative times compared to open procedures. Nevertheless, the adoption of LAP remains controversial due to challenges like limited working space in children and variability in the affected bowel segment. This study aims to investigate the safety and feasibility of LAP and mini-open reduction (MOR) techniques in treating idiopathic intussusception in pediatric patients. conditions: Intussusception studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 181 type: ACTUAL name: Laparoscopic reduction name: Transumbilical mini-open reduction measure: Operating time measure: Intraoperative complications measure: Immediate postoperative complications measure: Time to feed measure: Hospital stays measure: Recurrence rate measure: Long-term complication rate sex: ALL minimumAge: 2 Months maximumAge: 12 Years stdAges: CHILD facility: The National Hospital of Pediatrics city: Hanoi country: Vietnam lat: 21.0245 lon: 105.84117 facility: Vinmec Research Institute of Stem Cell and Gene Technology city: Hanoi country: Vietnam lat: 21.0245 lon: 105.84117 hasResults: False
nctId: NCT06351137 id: INIV2023 briefTitle: Timecost of Intranasal Versus Intravenous Analgesia in Traumatic Pain overallStatus: RECRUITING date: 2024-03-13 date: 2024-06-01 date: 2024-06-01 date: 2024-04-08 date: 2024-04-08 name: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) class: OTHER briefSummary: Prehospital treatment of acute traumatic pain is common in military practice. Analgesics are usually administered intravenously (IV). Research from the civil prehospital environment shows that obtaining IV access can be difficult and time consuming, delaying onset of treatment. The challenges for obtaining IV access in the military prehospital setting are even bigger, for example in combat environments. However, this has not been assessed.
Current guidelines also offer alternative routes of administration for analgesics, for example intranasal (IN) administration. IN administration is a fast, easy and effective route of administration. This study determines whether IN administration of analgesia is faster and leads to increased healthcare provider satisfaction compared to IV administration in patients with acute traumatic pain in a simulated military prehospital environment. conditions: Acute Pain Due to Trauma conditions: Analgesia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER primaryPurpose: TREATMENT masking: NONE count: 16 type: ESTIMATED name: Intravenous administration name: Intranasal administration measure: Time required for administration of analgesic (minutes) measure: Total time spent on scene (minutes) measure: Time required for obtaining IV access measure: Time required preparing IN administration measure: Satisfaction of the navy nurse regarding the used route of administration. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Amsterdam UMC status: RECRUITING city: Amsterdam state: Noord-Holland zip: 1105AZ country: Netherlands name: Midas N de Grunt, MD role: CONTACT phone: +31205669111 email: m.n.degrunt@amsterdamumc.nl name: Markus W Hollmann, PhD role: PRINCIPAL_INVESTIGATOR lat: 52.37403 lon: 4.88969 hasResults: False
nctId: NCT06351124 id: 00005294 briefTitle: Beta-Hydroxybutyrate Feasibility Treating IBS acronym: BHB overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-04-01 date: 2025-12-31 date: 2024-04-08 date: 2024-04-08 name: University of Texas at Austin class: OTHER briefSummary: This clinical trial aims to understand the feasibility of patients taking ketone body supplement beta-hydroxybutyrate (BHB) for 4 weeks with a confirmed diagnosis of Crohn's disease and starting new therapy for active disease.
Researchers will compare the group taking the ketone body supplement and the group not taking the supplement to see if the supplement provides relief of symptoms suffered from Crohn's disease. conditions: Crohn's Disease conditions: Irritable Bowel Syndrome studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: This will be a prospective, open-label, randomized, two-arm pilot trial of adults primaryPurpose: SUPPORTIVE_CARE masking: NONE maskingDescription: Eligible consenting patients will be randomized to either standard of care therapy (control) vs standard of care therapy plus BHB supplementation (intervention). BHB will be supplemented as a capsule taken orally three times daily for four weeks for those randomized to the intervention arm. count: 12 type: ESTIMATED name: Feasibility of beta-hydroxybutyrate supplementation to reduce inflammation in patients with Inflammatory Bowel Disease measure: Ability to enroll patients who meet the inclusion criteria within the target time frame measure: Adherence to proposed study timelines and anticipated study costs measure: Patient adherence to the intervention measure: Microbial Diversity measure: BHB Blood Levels measure: Gastrointestinal Symptoms measure: Quality of Life measure: Clinical Response measure: Systemic Inflammation measure: Adverse Events sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Texas at Austin city: Austin state: Texas zip: 78712 country: United States name: Michelle Stickler, Associate Vice President, DEd role: CONTACT phone: 512-475-6323 email: m.stickler@austin.utexas.edu name: Thomas Street, Executive Director role: CONTACT phone: 512 495 5142 email: thomas.street@austin.utexas.edu lat: 30.26715 lon: -97.74306 hasResults: False
nctId: NCT06351098 id: 2024579 briefTitle: Longitudinal Investigation of Sleep, Memory, and Brain Development Across the Nap Transition acronym: HSR overallStatus: RECRUITING date: 2023-11-05 date: 2028-06 date: 2028-06 date: 2024-04-08 date: 2024-04-08 name: University of Maryland, College Park class: OTHER name: University of Massachusetts, Amherst briefSummary: To examine the relations between sleep (nap transitions, sleep physiology), memory, and brain development longitudinally, the researchers will assess n=180 children (in order to acquire n=152 usable data sets) who are 36-54 months of age and habitual nappers at enrollment. In each wave, the researchers will assess memory, memory change over a nap and equivalent waking interval, sleep physiology of the nap, and brain structure and function (using Magnetic Resonance Imagining or MRI). Additionally, overnight sleep physiology will be assessed in all participants. Waves will take place approximately every 6 months. For all children, three waves will be collected. With these data, the researchers will address the following aims:
* Examine interrelations among brain, memory and sleep microstructure across the sleep transition (Aim 4) conditions: Memory studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 180 type: ESTIMATED name: nap measure: Memory sex: ALL minimumAge: 36 Months maximumAge: 60 Months stdAges: CHILD facility: University of Maryland status: RECRUITING city: College Park state: Maryland zip: 20742 country: United States name: Tracy Riggins, Ph.D. role: CONTACT phone: 301-405-5905 email: riggins@umd.edu name: Postdoctoral Fellow role: CONTACT phone: 301-405-5922 email: napstudy@umd.edu lat: 38.98067 lon: -76.93692 facility: University of Massachusetts status: RECRUITING city: Amherst state: Massachusetts zip: 01003 country: United States name: Rebecca MC Spencer, PhD role: CONTACT phone: 413-577-6128 email: rspencer@umass.edu name: Postdoctoral Fellow role: CONTACT phone: 413-545-4831 email: preschoolnapstudy@gmail.com lat: 42.36723 lon: -72.51852 hasResults: False
nctId: NCT06351085 id: 1937769-1 briefTitle: Enhancing Lung Cancer Screening Through Human-Centered Intervention acronym: ELFE overallStatus: RECRUITING date: 2022-11-10 date: 2025-04-14 date: 2025-04-14 date: 2024-04-08 date: 2024-04-08 name: University of California, Davis class: OTHER briefSummary: The purpose of this study is to further understand the factors involved in increasing lung cancer screening. conditions: Lung Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Patients of the intervention clinics will be assigned one of two interventions: 1) Pre Visit Planner (PVP) or 2) PVP + patient education delivered via the MyUCDHealth patient web portal. primaryPurpose: SCREENING masking: SINGLE maskingDescription: Biostatistician created a randomized table to allocate patient in either intervention 1 or 2. whoMasked: PARTICIPANT count: 2869 type: ESTIMATED name: Pre-Visit Planner name: Pre-Visit Planner + MyChart measure: Lung Cancer Screening measure: Completion of Interviews with Staff and Patients sex: ALL minimumAge: 50 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of California, Davis status: RECRUITING city: Sacramento state: California zip: 95817 country: United States name: Moon Chen, M.P.H, Ph.D role: CONTACT phone: 916-548-3928 email: mschenjr@ucdavis.edu name: Moon Chen, M.P.H, Ph.D role: PRINCIPAL_INVESTIGATOR lat: 38.58157 lon: -121.4944 hasResults: False
nctId: NCT06351072 id: NOXANI briefTitle: Correlation Between qNOX and Analgesia Nociception Index (ANI) Values During General Anesthesia acronym: ANI overallStatus: RECRUITING date: 2024-04-02 date: 2024-09-01 date: 2024-10-01 date: 2024-04-08 date: 2024-04-26 name: University of Padova class: OTHER briefSummary: qNOX and ANI are two indexes evaluting the analgesia conduction during general anesthesia.
No trials have compared them, so with this trial authors want to explore the correlations between them. conditions: Analgesia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 40 type: ESTIMATED measure: Correlation between qNOX and ANI values measure: Correlation between qNOX from CONOX and Analgesia nocicpetion index (ANI) values and postoperative pain measure: Correlation between qNOX from CONOX and analgesia nocicpetion index (ANI) values and postoperative delirium sex: FEMALE minimumAge: 18 Years maximumAge: 90 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Treviso Regional Hospital status: RECRUITING city: Treviso state: TV zip: 31100 country: Italy name: Federico Linassi role: CONTACT email: federico.linassi@gmail.com lat: 45.66673 lon: 12.2416 hasResults: False
nctId: NCT06351059 id: UE-0083 briefTitle: Acoustic Emission Biomarkers for the Detection and Monitoring of Early Knee Osteoarthritis overallStatus: ACTIVE_NOT_RECRUITING date: 2023-01-01 date: 2024-07-31 date: 2024-12-31 date: 2024-04-08 date: 2024-04-19 name: Schulthess Klinik class: OTHER name: Ecole Polytechnique Fédérale de Lausanne briefSummary: The aim of this exploratory study is to further investigate the potential of acoustic emission biomarkers, assessed by the inmodi knee brace, to diagnose osteoarthritis (OA) at earlier stages. Therefore, 20 healthy participants and 100 patients with increased risk of knee OA will be recruited from the Schulthess Klinik in Zurich and examined twice with 9 ± 3 months' time interval. Anthropometric data, EOS radiographs and MR images of both knees, PROMs and acoustic emission data will be collected and evaluated. Artificial Intelligence algorithm will then be used to identify and validate the most promising acoustic emission biomarkers with a prognosis value in the prediction of knee osteoarthritis progress. conditions: Osteoarthritis, Knee conditions: Diagnosis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 120 type: ACTUAL name: InModi acoustic emission analysis measure: acoustic emissions measure: kinematic data measure: MRI / MOAKS measure: EOS / leg alignment measure: PROMS sex: ALL minimumAge: 35 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Schulthess Klinik city: Zürich state: ZH zip: 8008 country: Switzerland lat: 47.36667 lon: 8.54999 hasResults: False
nctId: NCT06351046 id: NCT05178082_WP3 briefTitle: Preventive Interventions for Chronic Pain Worsening overallStatus: NOT_YET_RECRUITING date: 2024-08-01 date: 2026-07-30 date: 2027-01-30 date: 2024-04-08 date: 2024-04-08 name: Rigshospitalet, Denmark class: OTHER name: The Novo Nordic Foundation briefSummary: This is an open label randomized controlled trial (RCT), which will be conducted with patients of the Copenhagen Wound Healing Center at Bispebjerg Hospital in Copenhagen (DK). The trial has three arms (1:1:1): Mindfulness Based Stress Reduction (MBSR) group, Virtual Reality based Pain Self-management (VRPS) program group, and a control group (usual care). Included will be 78 patients at least 18 years old; fluent in the Danish language; complaint of pain lasting 3 months or more; in average pain intensity score ≥ 3 (numerical rating scale 0 to 10); access to internet; and willing and available to participate in the study. Excluded will be specialized or multidisciplinary pain treatment at baseline; history of epilepsy, seizure disorder, nausea or dizziness, hypersensitivity to flashing light or motion or other diseases that may prevent use of virtual reality equipment; injury to eyes, face or neck. conditions: Chronic Non-Cancer Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: FACTORIAL interventionModelDescription: This is an open label randomized controlled trial (RCT), which will be conducted with patients of the Copenhagen Wound Healing Center at Bispebjerg Hospital in Copenhagen (DK). The trial has three arms (1:1:1): MBSR group, VRPS group, and a control group (usual care). Participants will be randomly assigned to one of the groups. Assessments will occur at baseline and 2, 6, 9, and 12 months after intervention. primaryPurpose: PREVENTION masking: NONE maskingDescription: The statistical analysis of the data will be blinded count: 78 type: ESTIMATED name: Online Mindfullness Based Stress Reduction Program name: Virtual Reality-based Pain Self-management program measure: Pain intensity measure: Pain intensity and interference in daily activities measure: Pain catastrophizing measure: Pain acceptance measure: Health status measure: Health related quality of life measure: Anxiety measure: Depression measure: Use of medication measure: Use of healthcare system measure: Number of absent days at work measure: Satisfaction with the intervention sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06351033 id: ADP_012023 briefTitle: Ozonized Oil as Dietary Supplement in Macular Degeneration overallStatus: ACTIVE_NOT_RECRUITING date: 2023-10-31 date: 2024-12 date: 2024-12 date: 2024-04-08 date: 2024-04-08 name: Alba Di Pardo class: OTHER briefSummary: Macular degeneration, also called age-related macular degeneration (AMD), is a leading cause of visual impairment and severe vision loss.