hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06379074 id: 2022PMFMSE id: C53D23004250008 type: OTHER_GRANT domain: Italian Ministry of University and Research (MUR) briefTitle: Poor Sleep During Pregnancy as Risk Factor for Post-partum Stress and Mental Health acronym: MOTHERS overallStatus: NOT_YET_RECRUITING date: 2024-05-06 date: 2025-08-06 date: 2025-10-06 date: 2024-04-23 date: 2024-04-23 name: University of Rome G. Marconi class: OTHER name: University of Bologna name: University of the Italian Switzerland briefSummary: Improving maternal mental health is a worldwide health priority. Nevertheless, several scientific sources highlighted lack of empirical data which could drive clinical practice. The present project addresses psychobiological mechanisms leading to peripartum mental disorders. It focuses on one key risk factor for psychopathology, which is poor sleep continuity. The project aims to describe the link between maternal poor sleep quality and the cascade of events which may enhance vulnerability to stress and risk for mental disorders and to evaluate the efficacy of an online automated psychological prenatal intervention directed to sleep problems in preventing these negative outcomes. conditions: Postpartum Depression conditions: Insomnia conditions: Stress studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Participants will receive a personal e-mail address to access their reserved area of the study's website. Each e-mail address is created using the pre-defined pseudonymized code, which will be assigned to each participant after screening (participants with sleep difficulties will be randomly assigned a code for condition B1 or B2).
* B2: online questionnaire and sleep diaries; intervention's contents (videos and pdf); weekly optional private chat with a clinician (a psychotherapist expert in CBT-I and insomnia during pregnancy). primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Each participant will be assigned an identification code (ID-code) randomly generated by a computer. The codes associated to participants in Group B will be randomly assigned to intervention (Group B2) or placebo (Group B1). E-mail addresses will be created for each participant using the ID-code to access the private area of the study website. The code will be associated with responses to online questionnaires, actigraphy recording, saliva samples and sleep diaries. whoMasked: OUTCOMES_ASSESSOR count: 114 type: ESTIMATED name: Improving sleep health and resilience during pregnancy name: Information on pregnancy-related issues measure: Stress reactivity measure: Sleep efficiency measure: Depressive symptoms measure: Insomnia symptoms measure: Anxiety symptoms measure: Valence of affective states measure: Arousal of affective states measure: Emotion regulation measure: Mothers' parenting stress measure: Partners' insomnia symptoms measure: Children sleep difficulties measure: Partners' sleep efficiency measure: Fathers' parenting stress measure: Daytime sleepiness sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Biomedical and Neuromotor Sciences, Physiology campus, University of Bologna, Bologna, Italy city: Bologna zip: 40126 country: Italy name: Viviana Lo Martire role: CONTACT email: viviana.lomartire2@unibo.it name: Debora Meneo, M.Sc role: CONTACT phone: 06377251 email: d.meneo@unimarconi.it name: Debora Meneo, M.Sc role: PRINCIPAL_INVESTIGATOR name: Elisabetta Baldi, M.Sc role: SUB_INVESTIGATOR name: Silvia Cerolini, PhD role: SUB_INVESTIGATOR name: Viviana Lo Martire, PhD role: SUB_INVESTIGATOR name: Giuliana Simonazzi, PhD role: SUB_INVESTIGATOR name: Sara Curati, B.Sc role: SUB_INVESTIGATOR name: Stefano Bastianini, PhD role: SUB_INVESTIGATOR name: Chiara Berteotti, PhD role: SUB_INVESTIGATOR name: Mauro Manconi, PhD role: SUB_INVESTIGATOR name: Giovanna Zoccoli, PhD role: SUB_INVESTIGATOR name: Francesca Gelfo, PhD role: SUB_INVESTIGATOR name: Chiara Baglioni, PhD role: PRINCIPAL_INVESTIGATOR name: Paola De Bartolo, PhD role: SUB_INVESTIGATOR lat: 44.49381 lon: 11.33875 hasResults: False
nctId: NCT06379061 id: MM-01-24 briefTitle: Access MeMed BV Assay Clinical Study Collection Protocol - Infectious Adult and Pediatric Cohorts overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-12-31 date: 2025-03-31 date: 2024-04-23 date: 2024-04-23 name: Beckman Coulter, Inc. class: INDUSTRY name: MeMed Diagnostics Ltd. briefSummary: The purpose of the pivotal study is to collect blood specimens and clinical data from pediatric (\>90 days old) and adult (≥18 years old) patients presenting with signs and symptoms suggestive of acute bacterial or viral infection. These samples will be used to establish the diagnostic performance of MeMed BV™ for differentiating bacterial from viral infection using method comparison and/or method concordance. conditions: Infection, Bacterial conditions: Infection Viral studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 400 type: ESTIMATED measure: Blood Specimen Collection sex: ALL minimumAge: 90 Days maximumAge: 89 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06379048 id: 2021.12.282 briefTitle: The Impact of Different Skin Suture Methods in Episiotomy Repair on Healing and Pain overallStatus: COMPLETED date: 2022-03-01 date: 2022-08-31 date: 2022-09-20 date: 2024-04-23 date: 2024-04-23 name: Başakşehir Çam & Sakura City Hospital class: OTHER_GOV briefSummary: Episiotomy is the intentional incision of the perineum during vaginal birth in order to accelerate the active phase of labor. This study aimed to compare various skin closure techniques in episiotomy repair. conditions: Labor; Prolonged, Second Stage conditions: Episiotomy Wound studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 132 type: ACTUAL name: Matress Suturing name: Primary Suturing name: Continuous Subcutaneous Suturing measure: Healing by Redness, Edema, Ecchymosis and Discharge (REEDA) Score measure: Pain by Visual Analog Scale (VAS) sex: FEMALE minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Cam and Sakura City Hospital city: Istanbul state: Basaksehir zip: 34494 country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06379035 id: Protozoa in CRC patients briefTitle: Blastocystis and Cryptosporidium Infection in Colorectal Cancer Patients overallStatus: NOT_YET_RECRUITING date: 2024-11-01 date: 2025-11-01 date: 2025-12-31 date: 2024-04-23 date: 2024-04-23 name: Assiut University class: OTHER briefSummary: 1. Detect the prevelance of Blastocystis spp. and Cryptosporidium spp. among patients with colorectal cancer attending South Egypt Cancer Institute-Assiut University.
2. Detect the effect of Blastocystis and Cryptosporidium infection on various cytokines level in CRC patients that may be involved in the tumor progression. conditions: Blastocystis Infection conditions: Cryptosporidium Infection conditions: Colorectal Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 54 type: ESTIMATED name: ELISA / PCR measure: Detect the prevelance of Blastocystis spp. and Cryptosporidium spp. among patients with colorectal cancer attending South Egypt Cancer Institute-Assiut University. measure: Detect the effect of Blastocystis and Cryptosporidium infection on various cytokines level in CRC patients that may be involved in the tumor progression. sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06379022 id: AUTh-29/21-11-2018 briefTitle: Proteomic Analysis of Newly Restored Single Implants overallStatus: COMPLETED date: 2018-12-03 date: 2019-11-29 date: 2019-11-29 date: 2024-04-23 date: 2024-04-23 name: Aristotle University Of Thessaloniki class: OTHER name: Karolinska Institutet briefSummary: In 10 systemically healthy non-smokers, free of periodontitis, one newly restored implant (baseline-T0) and one corresponding tooth were followed over 12 months (T1). All implants were screw-retained, and platform-switched. Oral hygiene was closely monitored during the study. Probing pocket depth (PPD), attachment levels (CAL), bleeding and plaque indices and crevicular fluid were collected from an implant-site (PICF) and a tooth-site (GCF). Total proteomic profiles in PICF and GCF were investigated using label-free quantitative proteomics. conditions: Peri-Implantitis conditions: Peri-implant Mucositis conditions: Periodontal Diseases studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 10 type: ACTUAL name: Plaque control measure: Probing pocket depth measure: Protein expression measure: Recession measure: Bleeding upon probing measure: Inflammation index sex: ALL minimumAge: 18 Years maximumAge: 60 Years stdAges: ADULT facility: Dental School, Aristotle University city: Thessaloniki zip: 54124 country: Greece lat: 40.64361 lon: 22.93086 hasResults: False
nctId: NCT06379009 id: 473076 briefTitle: Effect of Home-based Training Program for Kidney Transplant Recipients (HOMETRAIN-KTR) overallStatus: RECRUITING date: 2024-02-07 date: 2027-01-01 date: 2028-01-01 date: 2024-04-23 date: 2024-04-24 name: Oslo University Hospital class: OTHER name: South-Eastern Norway Regional Health Authority briefSummary: Does home-based training work in kidney transplant recipients with reduced physical function?
* the effect of the training will be evaluated one year after the transplantation conditions: Kidney Transplant; Complications conditions: Frailty conditions: Physical Disability studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: 2 arms randomized control study. The intervention arm is exposed of a 12 week home-based training program. The control arm follow standard of care. primaryPurpose: TREATMENT masking: NONE maskingDescription: Both participants and investigators will know which arm the participants are randomized to. Training is not easy to mask count: 200 type: ESTIMATED name: Training measure: 6-minute walking distance test measure: Clinical Frailty Scale measure: Hand-grip strength measure: 30 seconds Sit-to-stand test measure: Bone density test measure: Bioelectrical impedance phase angle to measure muscle mass and strength. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Oslo University Hospital status: RECRUITING city: Oslo zip: 0372 country: Norway lat: 59.91273 lon: 10.74609 hasResults: False
nctId: NCT06378996 id: S68535 briefTitle: Arrhythmic Mitral Valve Prolapse Detection Using Long-term Ambulatory Rhythm Monitoring acronym: ALARM-PILOT overallStatus: RECRUITING date: 2024-05 date: 2024-09 date: 2024-10 date: 2024-04-23 date: 2024-04-23 name: Universitaire Ziekenhuizen KU Leuven class: OTHER briefSummary: Mitral valve prolapse (MVP) affects up to 3% of the general population and a small subset of patients is at risk for ventricular arrhythmias. This subgroup is referred to as AMVP (arrhythmic MVP) and was recently defined using the following criteria: (1) Presence of MVP), (2) Ventricular arrhythmia that is either frequent (≥5% total premature ventricular contraction (PVC) burden on Holter) or complex (non-sustained ventricular tachycardia (nsVT), ventricular tachycardia (VT), or ventricular fibrillation (VF)), and (3) The absence of any other well-defined arrhythmic substrate.
This pilot study aims to study the diagnostic yield of long-term rhythm monitoring in patients with MVP as well as the day-to-day variability of ventricular arrhythmias to facilitate power calculation for a future large-scale prospective registry. conditions: Mitral Valve Prolapse conditions: Ventricular Arrythmia studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Prospective, single arm, interventional cohort study including 3 different patient cohorts:
* Patients with MVP and severe mitral valve regurgitation scheduled for surgical intervention primaryPurpose: DIAGNOSTIC masking: NONE count: 60 type: ESTIMATED name: 14-day rhythm monitoring measure: Time to arrhythmic mitral valve prolapse detection measure: Number of days with high PVC-burden ≥5% measure: Number of days with complex ventricular arrhythmia (nsVT, VT, or VF) measure: Day-to-day variation in percentage PVC burden measure: Association between percentage PVC burden and percentage of late gadolinium enhancement on cardiac MRI measure: Association between mean number of nsVT episodes per 24hours and percentage of late gadolinium enhancement on cardiac MRI measure: Association between percentage PVC burden and global longitudinal strain on transthoracic echocardiography measure: Association between mean number of nsVT episodes per 24hours and global longitudinal strain on transthoracic echocardiography sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: UZ Leuven status: RECRUITING city: Leuven state: Vlaams-Brabant zip: 3000 country: Belgium name: Bert Vandenberk, MD, PhD role: CONTACT email: bert.vandenberk@uzleuven.be name: Bert Vandenberk, MD PhD role: PRINCIPAL_INVESTIGATOR lat: 50.87959 lon: 4.70093 hasResults: False
nctId: NCT06378983 id: SYSKY-2023-1149-02 briefTitle: Clinical Trial of Microneedle Radiofrequency Combined With Oral Isotretinoin in Moderate to Severe Acne overallStatus: RECRUITING date: 2022-09-01 date: 2024-06-30 date: 2024-06-30 date: 2024-04-23 date: 2024-04-23 name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University class: OTHER briefSummary: This study plans to select 100 AV patients and randomly divide them into two groups in a 1:1 ratio: the experimental group will be treated with MRF combined with oral isotretinoic acid for 8 consecutive weeks, with a total of 3 MRF treatments at weeks 1, 4, and 8. The control group received oral administration of isotretinoic acid alone for 8 weeks. The main observation indicators are the percentage of effective skin injury clearance achieved by subjects at week 20, as well as the change in ECCA acne scar score compared to baseline at week 20. I hope this study can clarify that the combination therapy of the two can achieve the effects of improving efficacy, shortening treatment course, reducing recurrence, not increasing adverse reactions, and reducing the risk of scar formation. conditions: Moderate to Severe Acne Vulgaris studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 100 type: ESTIMATED name: Oral isotretinoin name: Oral isotretinoin combined with microneedle radiofrequency therapy measure: Changes in ECCA acne scar score from baseline at week 20 measure: The percentage of effective skin lesion clearance rate in the 20th week sex: ALL minimumAge: 14 Years maximumAge: 65 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Department of Dermatology and Venereology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University. status: RECRUITING city: Guangzhou zip: 510030 country: China name: Sha Lu role: CONTACT phone: 13632383399 email: lush7@mail.sysu.edu.cn lat: 23.11667 lon: 113.25 hasResults: False
nctId: NCT06378970 id: 22-1T/49 briefTitle: Audio Books Effects on Anxiety and Vital Sings overallStatus: COMPLETED date: 2022-04-15 date: 2022-07-15 date: 2022-07-15 date: 2024-04-23 date: 2024-04-23 name: Ege University class: OTHER briefSummary: Objectives: This study aimed to investigate the effect of audio book use on anxiety and vital signs in patients receiving non-invasive mechanical ventilation (NIMV) support.
Research Methodology/Design: It is an experimental-randomised controlled study. Settings: The study was carried out with patients hospitalised in the Chest Diseases Intensive Care Unit of a university hospital and NIMV support. The participants consisted of 60 people, 30 in the intervention group and 30 in the control group. Before starting the application in the intervention group, the book preferences of the patients were determined and the selected audio book was played to the patients with headphones via tablet/smartphone. No additional application was made to the control group.
Main Outcome Measures: Anxiety levels and vital signs in the intervention group were evaluated before, 15 minutes, 30 minutes and 30 minutes after the end of the intervention. In the control group, only routine care continued and anxiety levels, and vital signs were assessed simultaneously with the intervention group. conditions: Non-invasive Mechanical Ventilation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Randomised Controlled primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 60 type: ACTUAL name: Audio Book Application measure: Facial Anxiety Scale measure: Patient Follow-up Form measure: Audio Book Application Preference Form measure: Patient Information Form sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ege University city: Bornova state: İzmir zip: 35100 country: Turkey lat: 38.47921 lon: 27.2399 hasResults: False
nctId: NCT06378957 id: IRB00436545 briefTitle: Behavioral Pharmacology of Orally Administered THC and D-limonene overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2027-07-01 date: 2027-12-31 date: 2024-04-23 date: 2024-04-23 name: Johns Hopkins University class: OTHER name: National Institutes of Health (NIH) briefSummary: The current clinical trial will investigate the effects of orally administered d-limonene (limonene), delta-9-tetrahydrocannabinol (THC) and the combination in healthy adult volunteers. conditions: Subjective Drug Effects conditions: THC conditions: D-limonene studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Within-subjects design where participants are randomly assigned to dose conditions primaryPurpose: BASIC_SCIENCE masking: DOUBLE maskingDescription: place controlled, double-blind whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 65 type: ESTIMATED name: D-Limonene name: Delta-9-THC name: Placebo measure: Subjective Drug Effect as assessed by Visual Analog Scale measure: Subjective Drug Liking as assessed by Visual Analog Scale measure: Subjective anxiety as assessed by Visual Analog Scale measure: Subjective hunger as assessed by Visual Analog Scale measure: Subjective paranoia as assessed by Visual Analog Scale sex: ALL minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: Johns Hopkins Behavioral Pharmacology Research Unit city: Baltimore state: Maryland zip: 21224 country: United States lat: 39.29038 lon: -76.61219 hasResults: False
nctId: NCT06378944 id: 61/23 briefTitle: Selective Sentinella Lymph Node Biopsy With Indocyanine Green in Patients With Breast Cancer acronym: INSEAN overallStatus: RECRUITING date: 2024-01-01 date: 2029-01-01 date: 2029-01-01 date: 2024-04-23 date: 2024-04-23 name: Omphis Foundation class: OTHER briefSummary: The current observational study aims to perform the sentinel lymph node in breast cancer in the usual way with technetium 99 and add a second tracer, indocyanine green. The objective is to evaluate the detection rate of the lymph node with indocyanine green compared to the usual technique. conditions: Breast Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 15000 type: ESTIMATED name: Application of green indocyanine colorant name: Technetium99 measure: Number of Sentinel lymph node detected. Scale of numbers measure: Number of possitive lymph nodes measure: surgery time in minutes sex: ALL minimumAge: 18 Years maximumAge: 120 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Sandra Lopez Gordo status: RECRUITING city: Cerdanyola Del Valles state: Barcelona zip: 08290 country: Spain name: Sandra Lopez gordo role: CONTACT phone: 660284047 email: sandra.lopezgordo@gmail.com lat: 41.49109 lon: 2.14079 hasResults: False
nctId: NCT06378931 id: 2024HX161 briefTitle: Quality of Life Change in Patients Undergoing Parathyroidectomy With End-stage Renal Failure overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-12-30 date: 2025-12-30 date: 2024-04-23 date: 2024-04-23 name: Chunling Jiang class: OTHER briefSummary: The purpose of this study is to characterize the quality of life change in patients undergoing parathyroidectomy with secondary hyperparathyroidism due to end-stage renal failure. conditions: Secondary Hyperparathyroidism conditions: End Stage Renal Failure studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 80 type: ESTIMATED name: Quality of life progression after parathyroidectomy measure: Measure quality of life scores change with respect to time measure: Measure anxiety and depression score change with respect to time measure: Measure bone pain scores change with respect to time measure: Length of hospital stay sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06378918 id: 2023-A02791-44 briefTitle: Comparison of the Effectiveness of the Simple Puncture Compared to the Incision of an Abscess on the piLOnidal Sinus acronym: PILO overallStatus: NOT_YET_RECRUITING date: 2024-06-15 date: 2025-04-15 date: 2027-04-15 date: 2024-04-23 date: 2024-04-23 name: University Hospital, Angers class: OTHER_GOV briefSummary: Pilonidal disease is a common disease characterized by the presence of abscess in the intergluteal groove. During periods of abscess, current recommendations are to make a simple incision with daily wicking of the abscess. Direct excision at this time is not recommended because there is a risk of incomplete excision. The principle of directed healing after incision of the abscess results in an average dressing period of 21 days. A definitive resection is recommended after 4 to 6 weeks, when healing has been achieved, in order to limit the risk of infectious recurrence.
The research hypothesis is that the two techniques have the same results in terms of recurrence before definitive surgical treatment but that drainage puncture would imply a faster healing time, a lower cost of treatment, a quality of superior support, reduced support time and reduced work stoppage. conditions: Pilonidal Cyst studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 134 type: ESTIMATED name: puncture name: incision of the abscess measure: healing time measure: Effectiveness of the 2 procedures measure: Cost-utility analysis measure: Duration of nursing care measure: Duration of work stoppage measure: Returning to work measure: Quality of life measure: Healing after definitive resection sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False