In addition, hydrogen intake can reduce oxidative stress, improve cellular function, and reduce chronic inflammation, which are associated with the pathology and etiology of hyperlipidemia and other related diseases. Molecular hydrogen can regulate important metabolic functions such as signal transduction, protein phosphorylation, miRNA expression, and autophagy. Studies have shown that intake of hydrogen water in APOE knockout mice can reduce serum total cholesterol and low-density lipoprotein levels and prevent the progression of atherosclerosis. A study by Song et al. in 2013 included 20 subjects who drank 0.9 to 1 L of hydrogen-rich water per day for 10 weeks, and the subjects' LDL-C levels decreased significantly before and after treatment. Another study showed that subjects with underlying lipid metabolism abnormalities were treated with high-concentration hydrogen water (5.5mmol/d) for up to 24 weeks, and serum total cholesterol and low-density lipoprotein levels were significantly reduced. Protein function and redox status (eg, increased serum superoxide dismutase and decreased malondialdehyde) were improved, markers of inflammation (eg, serum tumor necrosis factor-alpha) decreased and fasting blood glucose decreased. At present, the research on the treatment of hyperlipidemia with hydrogen water is very limited. The portable hydrogen water hydrogen machine used in this study has passed the registration test of the Guangdong Provincial Medical Device Quality Supervision and Inspection Institute. In order to evaluate the use of the portable hydrogen water hydrogen machine for hyperlipidemia The efficacy and safety of adjuvant therapy in patients, this clinical trial is specially carried out. conditions: Hyperlipidemias studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: It is estimated that 180 subjects will be enrolled and randomly divided into the experimental group and the control group according to 2:1. During the observation period, the experimental group drink the hydrogen water prepared by the experimental equipment on the basis of the general dietary guidance, while the control group adopted the general dietary guidance. Every subject's diet and lifestyle remains largely unchanged during the treatment period. primaryPurpose: TREATMENT masking: NONE count: 180 type: ESTIMATED name: General dietary guidance and hydrogen water prepared by portable hydrogen rich water machine measure: Percent change from baseline in LDL-C at 3 months of intervention. measure: Absolute change from baseline in LDL-C at 3 months of intervention. measure: Percent change from baseline in LDL-C at 1 month of intervention. measure: Absolute change from baseline in LDL-C at 1 month of intervention. measure: Percent change from baseline in LDL-C at 6 months of intervention. measure: Absolute change from baseline in LDL-C at 6 months of intervention. measure: Percent change from baseline in triglycerides at 1 month of intervention. measure: Absolute change from baseline in triglycerides at 1 month of intervention. measure: Percent change from baseline in triglycerides at 3 months of intervention. measure: Absolute change from baseline in triglycerides at 3 months of intervention. measure: Percent change from baseline in triglycerides at 6 months of intervention. measure: Absolute change from baseline in triglycerides at 6 months of intervention. measure: Percent change from baseline in total cholesterol at 1 month of intervention. measure: Absolute change from baseline in total cholesterol at 1 month of intervention. measure: Percent change from baseline in total cholesterol at 3 months of intervention. measure: Absolute change from baseline in total cholesterol at 3 months of intervention. measure: Percent change from baseline in total cholesterol at 6 months of intervention. measure: Absolute change from baseline in total cholesterol at 6 months of intervention. measure: Percent change from baseline in HDL cholesterol at 1 month of intervention. measure: Absolute change from baseline in HDL cholesterol at 1 month of intervention. measure: Percent change from baseline in HDL cholesterol at 3 months of intervention. measure: Absolute change from baseline in HDL cholesterol at 3 months of intervention. measure: Percent change from baseline in HDL cholesterol at 6 months of intervention. measure: Absolute change from baseline in HDL cholesterol at 6 months of intervention. measure: Percent change from baseline in non-HDL cholesterol at 1 month of intervention. measure: Absolute change from baseline in non-HDL cholesterol at 1 month of intervention. measure: Percent change from baseline in non-HDL cholesterol at 3 months of intervention. measure: Absolute change from baseline in non-HDL cholesterol at 3 months of intervention. measure: Percent change from baseline in non-HDL cholesterol at 6 months of intervention. measure: Absolute change from baseline in non-HDL cholesterol at 6 months of intervention. measure: Percent change from baseline in small and dense LDL at 1 month of intervention. measure: Absolute change from baseline in small and dense LDL at 1 month of intervention. measure: Percent change from baseline in small and dense LDL at 3 months of intervention. measure: Absolute change from baseline in small and dense LDL at 3 months of intervention. measure: Percent change from baseline in small and dense LDL at 6 months of intervention. measure: Absolute change from baseline in small and dense LDL at 6 months of intervention. measure: Percent change from baseline in apolipoprotein B at 1 month of intervention. measure: Absolute change from baseline in apolipoprotein B at 1 month of intervention. measure: Percent change from baseline in apolipoprotein B at 3 months of intervention. measure: Absolute change from baseline in apolipoprotein B at 3 months of intervention. measure: Percent change from baseline in apolipoprotein B at 6 months of intervention. measure: Absolute change from baseline in apolipoprotein B at 6 months of intervention. measure: Percent change from baseline in TNF-alpha at 1 month of intervention. measure: Absolute change from baseline in TNF-alpha at 1 month of intervention. measure: Percent change from baseline in TNF-alpha at 3 months of intervention. measure: Absolute change from baseline in TNF-alpha at 3 months of intervention. measure: Percent change from baseline in TNF-alpha at 6 months of intervention. measure: Absolute change from baseline in TNF-alpha at 6 months of intervention. measure: Adverse Event (AE) Frequency measure: Severe Adverse Event (SAE) Frequency measure: Device deficiency rate sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Zhujiang Hospital of Southern Medical University status: RECRUITING city: Guangzhou state: Guangdong country: China name: Sun Jia role: CONTACT phone: 13751822925 lat: 23.11667 lon: 113.25 hasResults: False