hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06262828 id: UW 24-064 briefTitle: HEARTWISE - P-CARDIAC for Chinese: Population-based Study acronym: HEARTWISE overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2027-01-31 date: 2027-04-30 date: 2024-02-16 date: 2024-02-16 name: The University of Hong Kong class: OTHER briefSummary: Cardiovascular disease (CVD) is one of the prominent diseases that affect many people. One cost-effective solution is to identify people at higher risk of CVD by CVD risk prediction model. China-PAR, TRS-2P, and SMART2 are common risk prediction models for prevention. However, these risk scores were mostly based on the routinely self-check health information and multivariable regression without time-varying consideration. Investigators developed a Machine Learning (ML) based risk prediction model, Personalized CARdiovascular DIsease risk Assessment for Chinese (P-CARDIAC) among a predominantly Chinese population in Hong Kong to estimates the 10 years of secondary recurrent CVD risk for the high-risk individuals. The study objective is to evaluate the accuracy of the P-CARDIAC performance in practice among a large-scale Hong Kong population in medicine specialist outpatient clinic (SOPC) and cardiac clinic. The results will reassure cardiologists that the P-CARDIAC risk score is sensitive to the heart disease symptoms. Investigators anticipate that the results may help to facilitate P-CARDIAC in clinical setting and provide more practical information with the development of P-CARDIAC. conditions: Cardiovascular Diseases conditions: CVD studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 800 type: ESTIMATED measure: The relationship between P-CARDIAC risk score and heart disease related symptoms measure: P-CARDIAC risk thresholds determination sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: School of Nursing, The University of Hong Kong city: Hong Kong country: Hong Kong name: Sze Ling Celine Chui, PhD role: CONTACT phone: (852) 3917 6629 email: cslchui@hku.hk lat: 22.27832 lon: 114.17469 typeAbbrev: Prot_SAP hasProtocol: True hasSap: True hasIcf: False label: Study Protocol and Statistical Analysis Plan date: 2023-10-31 uploadDate: 2024-01-31T01:00 filename: Prot_SAP_000.pdf size: 294821 hasResults: False
nctId: NCT06262815 id: 2023-06806-01 briefTitle: The Utility of Treatment With Nasogastric Tube Placement for Small Bowel Obstruction acronym: NGTUBE-OBS overallStatus: RECRUITING date: 2024-01-01 date: 2024-12-31 date: 2024-12-31 date: 2024-02-16 date: 2024-02-16 name: Daniel Wilhelms class: OTHER name: Linkoeping University briefSummary: Small bowel obstruction (SBO) occurs when the normal movements of the small bowel is obstructed, most commonly due to adhesion related to previous abdominal surgery. This may cause strangulation of the small bowel with reduced blood flow which is a surgical emergency requiring prompt treatment in the operating room. If there are no signs of strangulation or ischemia of the bowel at the time of diagnosis, international guidelines recommend initial treatment with intravenous fluids and nasogastric tube placement. However, there is emerging debate regarding non-selective treatment with nasogastric tube placement in patients with SBO. This management started around 1930 as a means to reduce pain in patients with SBO, in conjunction with other additions to management, like intravenous fluids. However the effect and utility of routine nasogastric tube placement have not been prospectively evaluated. There are a total of three retrospective observational studies in the past decade with a total of 759 patients where 292 (36%) were managed without a nasogastric tube. There was no difference in the rates of conservative treatment failure (requiring surgery), complications (vomiting, pneumonia) or mortality between patients receiving a nasogastric tube and those who didn't. However, the retrospective design of these studies limits their validity. Furthermore, nasogastric tube placement has been shown to be one of the more painful interventions patients may experience in-hospital. This calls into question the patient benefit of routine nasogastric tube placement in patients with SBO and further studies are needed to discern the utility of this intervention.
Definitive treatment for SBO is surgical adhesiolysis but there is debate regarding the timing of surgery, particularly in older adults. A large proportion of patients may be managed conservatively with oral contrast and repeated radiological evaluation and the obstruction will resolve in many patients within 24 to 48 hours. This timeframe is dependent on factors related to the disease itself as well as patient related factors like previous surgery and comorbidities. Older patients are at high risk for complications but current available data is insufficient to inform practice in this population. Frailty, a state of increased vulnerability and susceptibility to adverse events, has been shown to be an independent prognosticator in older adults in the Emergency Department(ED) and suggested as a potential measure to risk stratify older adults with SBO. However to the authors knowledge there is no available data on frailty in older adults with SBO and only one prospective observational trial looking at older adults with SBO. Despite SBO being one of the most common surgical emergencies in older adults.
To investigate the potential benefit of nasogastric tube placement in patients with SBO and the ability of frailty to prognosticate outcomes in older adults better evidence is needed. conditions: Small Bowel Obstruction conditions: Frailty conditions: Nasogastric Tube studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 400 type: ESTIMATED name: Nasogastric tube placement name: Clinical Frailty Scale measure: Pain at Emergency Department discharge measure: Nausea at Emergency Department discharge measure: Hospital Length of Stay measure: Mortality measure: Admission for Small bowel obstruction measure: Emergency Surgery measure: Emergency Department Length of Stay sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Sahlgrenska Universitetssjukhuset status: RECRUITING city: Göteborg country: Sweden name: Nina Bardhi, MD role: CONTACT lat: 57.70716 lon: 11.96679 facility: Östra sjukhuset status: RECRUITING city: Göteborg country: Sweden name: Mathias Jerkfelt, MD role: CONTACT lat: 57.70716 lon: 11.96679 facility: Skånes Universitetssjukhus status: ACTIVE_NOT_RECRUITING city: Lund country: Sweden lat: 55.70584 lon: 13.19321 facility: Skånes Universitetssjukhus status: ACTIVE_NOT_RECRUITING city: Malmö country: Sweden lat: 55.60587 lon: 13.00073 facility: Lasarett i Motala status: RECRUITING city: Motala country: Sweden name: Jens Wretborn, PhD role: CONTACT phone: +46101033000 email: jens.wretborn@regionostergotland.se lat: 58.53706 lon: 15.03649 facility: Vrinnevisjukhuset status: RECRUITING city: Norrköping country: Sweden name: Sigrid Wallden, MD role: CONTACT lat: 58.59419 lon: 16.1826 facility: Sundsvalls sjukhus status: RECRUITING city: Sundsvall country: Sweden name: Robert Schytzer, MD role: CONTACT lat: 62.39129 lon: 17.3063 facility: Akutmottagningen US Östergötland status: RECRUITING city: Linköping state: Östergötland zip: 58185 country: Sweden name: Jens Wretborn, PhD role: CONTACT phone: +46101033000 email: jens.wretborn@regionostergotland.se name: Alaa Hussein, MD role: CONTACT phone: +46101033000 email: alaa.hussein@regionostergotland.se lat: 58.41086 lon: 15.62157 hasResults: False
nctId: NCT06262802 id: 123123 briefTitle: Volumetric Changes in Large Cystic Lesions Using Active Decompression and Distraction Sugosteogenesis vs Passive Decompression overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-09-01 date: 2025-03-01 date: 2024-02-16 date: 2024-02-16 name: Radwa Hydar Ragab class: OTHER briefSummary: Null hypothesis active decompression and distraction sugosteogenesis is not faster than passive decompression in volume reduction of large cystic lesions conditions: Odontogenic Cysts studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: DEVICE_FEASIBILITY masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 10 type: ESTIMATED name: Active decompression measure: Volume change sex: ALL minimumAge: 12 Years maximumAge: 80 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06262776 id: SIRZOSTER1.01 briefTitle: Safety and Immunogenicity of Recombinant Zoster Vaccine for Kidney Transplant Recipients acronym: SIR ZOSTER overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2025-06 date: 2026-11 date: 2024-02-16 date: 2024-02-16 name: Central Adelaide Local Health Network Incorporated class: OTHER_GOV name: National Health and Medical Research Council, Australia name: University of Adelaide name: Royal Prince Alfred Hospital, Sydney, Australia briefSummary: The goal of this clinical trial is to compare responses to Varicella Zoster vaccination between kidney transplant patients on different medication regimens, and their healthy co-habitants. The main questions it aims to answer are:
2. Are there differences in vaccination immunological responses between kidney transplant patients and their healthy co-habitants? Participants will all receive a 2-dose course of SHINGRIX recombinant Zoster vaccination, and have immunological responses measured and compared at 5 timepoints between 1 week to 1 year post-vaccination. conditions: Immunosuppression conditions: Vaccine Response Impaired studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: PREVENTION masking: NONE count: 120 type: ESTIMATED name: Recombinant zoster vaccine adjuvanted (SHINGRIX) measure: Functional T cell memory measure: Frequency of virus specific T cells measure: Magnitude of antibody response measure: Concentration of post-vaccination circulating cytokines measure: Frequency of polyfunctional T cells measure: Magnitude of vaccine-induced cross-protective antiviral responses measure: Frequency of virus-specific T stem cell memory compared to baseline measure: Incidence of shingles measure: Number of participants with treatment-related adverse events as assessed by CTCAE v4.0 measure: Tolerability of vaccination regimen as assessed by EQ-5D sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06262763 id: HILT for SIJP briefTitle: High-intensity Laser Therapy for Sacroiliac Joint Pain acronym: Girls overallStatus: ACTIVE_NOT_RECRUITING date: 2023-01-03 date: 2023-04-28 date: 2024-03-28 date: 2024-02-16 date: 2024-02-16 name: Kafrelsheikh University class: OTHER briefSummary: Effect of high intensity laser on sacroiliac joint pain conditions: Sacroiliac Joint Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 30 type: ACTUAL name: Laser Therapy name: Traditional exercises name: Placebo laser measure: Pain intensity measure: Pressure pain threshold measure: Functional disability sex: FEMALE minimumAge: 18 Years maximumAge: 30 Years stdAges: ADULT facility: Kafr Al-Sheikh University city: Kafr Ash Shaykh country: Egypt lat: 31.11174 lon: 30.93991 hasResults: False
nctId: NCT06262750 id: 00375/23 briefTitle: Evaluation of Safety and Efficacy of Anticoagulation Treatment in Patients With Splanchnic Vein Thrombosis: SAPIENT Study acronym: SAPIENT overallStatus: RECRUITING date: 2023-12-01 date: 2023-12-01 date: 2025-11-01 date: 2024-02-16 date: 2024-02-16 name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS class: OTHER briefSummary: Prospective single-centre, observational study with medical products. Patients with a medical history of SVT will be observed for at least 24 months after inclusion. The study will begin when the patient is referred to our centre for SVT and will end at the 24-month follow-up or at the occurrence of a study outcome event, or in case of Death OBJECTIVE: To prospectively define the incidence of recurrent thrombosis and bleeding events during anticoagulant therapy in patients with diagnosed SVT, regardless of whether they will be hospitalized or treated as outpatients conditions: Splanchnic Vein Thrombosis studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 170 type: ESTIMATED measure: Incidenze of bleedings events measure: Incidence of venous and arterial thromboembolic events measure: Rate of progress /stable /regressive measure: incidence of liver related events sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: UOC Servizio e DH Ematologia status: RECRUITING city: Rome zip: 00168 country: Italy name: Valerio De Stefano role: CONTACT name: Rossella Talerico role: SUB_INVESTIGATOR name: Silvia Betti role: SUB_INVESTIGATOR name: Francesco Santopaolo role: SUB_INVESTIGATOR lat: 41.89193 lon: 12.51133 hasResults: False
nctId: NCT06262737 id: RBHP 2023 CHIAMBARETTA id: 2023-A01121-44 type: REGISTRY domain: ANSM briefTitle: Single-center Study Measuring OSDI Dry Eye Score in Patients Undergoing an Anti-VEGF Induction Protocol acronym: PISO overallStatus: RECRUITING date: 2023-09-30 date: 2024-10-01 date: 2025-10-01 date: 2024-02-16 date: 2024-02-16 name: University Hospital, Clermont-Ferrand class: OTHER briefSummary: The purpose of this study is to assess the sensation of ocular dry eye symptom after an intravitreal injection of anti-VEGF. conditions: Macular Degeneration conditions: Diabetic Macular Edema conditions: Retinal Vein Occlusion studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 50 type: ESTIMATED measure: OSDI measure: OSDI measure: HM measure: AM measure: NIBUT 1 measure: NIBUT 2 measure: Interferometry sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: CHU de Clermont-Ferrand status: RECRUITING city: Clermont-Ferrand zip: 63000 country: France lat: 45.77966 lon: 3.08628 hasResults: False
nctId: NCT06262724 id: Perforator Flaps briefTitle: Breast Reshaping Following Massive Weight Loss overallStatus: COMPLETED date: 2021-08-01 date: 2023-08-01 date: 2024-01-01 date: 2024-02-16 date: 2024-02-26 name: Ain Shams University class: OTHER briefSummary: Reliability of Chest Wall Perforator Flaps for Breast Reshaping following Massive Weight Loss conditions: Breast Ptosis studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: All patients were subjected to the same intervention. primaryPurpose: TREATMENT masking: NONE count: 20 type: ACTUAL name: Breast auto-augmentation measure: Measurement of breast volume by sono-mammography measure: Sternal notch to nipple distance measure: Nipple to inframammary fold distance measure: Measure of nipple-to-nipple distance sex: FEMALE minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Faculty of Medicine, Ain Shams University city: Cairo state: Abbasia zip: 11591 country: Egypt lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06262711 id: 321917 briefTitle: Effects of Vitamin C on Skeletal Muscle acronym: VICS overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2025-03 date: 2025-03 date: 2024-02-16 date: 2024-02-16 name: University of East Anglia class: OTHER name: The Norfolk and Norwich University Hospitals NHS Foundation Trust name: The Quadram Institute Clinical Research Facility briefSummary: As part of the ageing process muscles become weaker. One of the reasons for this is that mitochondria, the 'engines' that provide energy to fuel muscles, age and work less efficiently. Mitochondria are found in almost all cells in the human body. Mitochondria take in nutrients that are provided from food and break these down to create energy-rich compounds to fuel many different processes in the body. Muscles are loaded with mitochondria because they require a lot of energy. Mitochondria naturally produce small compounds called oxidants that can damage muscle cells and can cause inflammation. The cells in the body have a natural defence system to protect against oxidants, but when mitochondria age and become less efficient, the amount of oxidants that they produce can increase. These oxidants can damage muscles and the mitochondria themselves. Antioxidants, such as vitamin C, may help protect muscles from the damage caused by oxidants, and may help mitochondria work more efficiently. In this study, the investigators will explore whether vitamin C can help mitochondria work more efficiently, which may improve muscle strength, and help older people to remain mobile and independent for longer. conditions: Healthy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Crossover Assignment primaryPurpose: BASIC_SCIENCE masking: TRIPLE maskingDescription: Double blind masking whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 16 type: ESTIMATED name: Vitamin C name: Placebo measure: Difference in skeletal muscle mitochondrial function between vitamin C and placebo groups. measure: Difference in skeletal muscle phosphomonoester to phosphodiester ratio (PME/PDE) between vitamin C and placebo groups. measure: Difference in knee extension strength between vitamin C and placebo groups. measure: Difference in hand grip strength between vitamin C and placebo groups. measure: Difference in Short Physical Performance Battery (SPPB) score between vitamin C and placebo groups. measure: Difference in plasma vitamin C between vitamin C and placebo groups. measure: Difference in serum hs-CRP between vitamin C and placebo groups. measure: Difference in serum IL-6 between vitamin C and placebo groups. measure: Difference in serum TNF-α between vitamin C and placebo groups. measure: Difference in plasma P1NP between vitamin C and placebo groups. measure: Difference in plasma CTX between vitamin C and placebo groups. sex: FEMALE minimumAge: 65 Years stdAges: OLDER_ADULT facility: University of East Anglia city: Norwich state: Norfolk zip: NR4 7TJ country: United Kingdom lat: 52.62783 lon: 1.29834 hasResults: False
nctId: NCT06262698 id: 81825902.903/148 briefTitle: The Effect of HBM-Based Education on Nursing Students acronym: HBM overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2024-12-31 date: 2025-06-30 date: 2024-02-16 date: 2024-02-16 name: Kafkas University class: OTHER briefSummary: The purpose of the study is to investigate the effect of HBM-based education on CAM knowledge, attitudes, and health beliefs related to medication use among nursing students through a randomized controlled trial.
Hypothesis 3: There is an effect of HBM-based education on health beliefs related to medication use among nursing students. conditions: Nursing conditions: Evidence-Based Nursing studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: The experimental group will receive six weeks of HBM-based training. primaryPurpose: PREVENTION masking: TRIPLE maskingDescription: Participants were assigned to groups using the "simple randomization method". Participants were not informed of which group they were in. Automated computer-based randomization resulted in the implementation of the experiment with the scheduling scenario and confidential allocation of participants to one of the four intervention branches. The researcher was blind to all conditions until the participants started the computer program and the intervention began. Participants were also unaware of whether the group they were assigned to was an experimental or a control condition. In addition, researchers coding and analyzing data will be blind to randomization and interventions. whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 120 type: ESTIMATED name: Experiment group name: Pre-post test measure: The TCM Attitude Scale (CACMAS) The GETAT Attitude Scale (CACMAS): The scale, developed by McFadden et al. (2010), consists of 27 items rated on a 7-point Likert scale. Its Turkish validity and reliability were established by Köse et al. (2018). measure: The Medication Health Belief Scale sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Kafkas University Faculty of Health Sciences city: Kars zip: 36500 country: Turkey name: Gönül GÖKÇAY, Asist. Prof. role: CONTACT phone: 05447915549 email: gonul.gokcay@ogr.sakarya.edu.tr lat: 40.59825 lon: 43.08548 hasResults: False
nctId: NCT06262672 id: PR0319R01 briefTitle: Evaluation of Some Parameters in University Students During the COVİD-19 Epidemic Process overallStatus: COMPLETED date: 2021-05-20 date: 2021-11-20 date: 2021-11-20 date: 2024-02-16 date: 2024-02-28 name: Kırklareli University class: OTHER briefSummary: The physical and mental effects of the COVID-19 pandemic have been examined by many researchers, but this study aims to evaluate in every aspect how university students who had to receive education with the distance education model due to the pandemic went through this process. Data regarding people's positive and negative habits from anthropometric characteristics and sleep quality, which is one of the sub-dimensions of healthy lifestyle behaviors, were evaluated, and the relationship between these parameters was examined in detail. conditions: Health Behavior conditions: Sleep conditions: Body Weight studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 236 type: ACTUAL name: Evaluation form measure: Health Promotion Life-Style Profile (HPLP-II) measure: Pittsburgh Sleep Quality Index (PSQI) measure: Anthropometric Measurements sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Kirklareli University city: Kirklareli state: Kayalı zip: 39000 country: Turkey lat: 41.73508 lon: 27.22521 hasResults: False
nctId: NCT06262659 id: 2023-142 briefTitle: The Effect of Ultrasonography on Blood Flow,Vessel Diameter,and Depth Measurements in Dialysis Patients With Fistula overallStatus: RECRUITING date: 2024-03-08 date: 2024-06-10 date: 2024-09-10 date: 2024-02-16 date: 2024-03-12 name: Kudret Atakan Tekin class: OTHER briefSummary: Arteriovenous fistulas (AVF) are considered essential and the primary vascular access for end-stage renal disease patients to receive hemodialysis (HD) treatment. The maturation failure rate of AVFs is approximately 23%. The aim of our study is to compare intraoperative fistula flow and measurements of vascular structures' diameters with postoperative fistula maturation, following the completion of the fistula operation, to reveal the relationship between them. Providing insights into the need for intraoperative intervention and/or postoperative fistula management based on these measurements is intended to contribute to the literature by offering predictions and perspectives. conditions: Arteriovenous Fistula studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 66 type: ESTIMATED name: Doppler Ultrasonography Assessment measure: intraoperative Arteriovenous Fistula Flow Measurement sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Kudret Atakan Tekin status: RECRUITING city: Merkez state: Çorum country: Turkey name: Kudret Atakan Tekin role: CONTACT phone: 05424912184 email: dr.kudretatakantekin@gmail.com hasResults: False