hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06357429 id: 171002100 briefTitle: Evaluation of the Effect of the LI4 Cold Application acronym: LI4 overallStatus: COMPLETED date: 2022-02-23 date: 2022-11-18 date: 2022-11-18 date: 2024-04-10 date: 2024-04-10 name: Saglik Bilimleri Universitesi class: OTHER briefSummary: It is an experimental study conducted to evaluate the effectiveness of cold application to the LI4 point of the hand to reduce/eliminate pain, nausea and anxiety in postoperative patients. The population of the study consisted of 116 individuals who underwent abdominal surgery with the open surgery method in a state hospital between February 2022 and November 2022 and were followed up in the inpatient ward. The study was completed with 80 individuals constituting the experimental group (n=40) and the control group (n=40). Patient information form, Mcgill Melzack short pain form, Visual Analog Scale, STAI - TX and Cold Application Evaluation Form were used to collect data. Patients in the experimental group underwent cold application with ice cubes for a total of 20 minutes as 2 minutes of cold application and 15 seconds of waiting 4-6 hours after the patient was admitted to the clinic after surgical intervention. Follow-up was performed before cold application, immediately after cold application, 30 minutes after the end of cold application, 1 hour and 2 hours after the end of cold application. conditions: Pain conditions: Nausea conditions: Anxiety studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: PARTICIPANT count: 80 type: ACTUAL name: Cold Application measure: Pain Level measure: Nausea Level measure: Anxiety Level measure: Sensory characteristics, intensity and impact of pain sex: FEMALE minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Saglik Bilimleri University city: Istanbul state: Uskudar zip: 34674 country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06357416 id: CCR5573 briefTitle: The Man Van Project acronym: MV overallStatus: RECRUITING date: 2022-04-13 date: 2025-10-01 date: 2026-12-01 date: 2024-04-10 date: 2024-04-10 name: Royal Marsden NHS Foundation Trust class: OTHER name: RM Partners West London Cancer Alliance name: Institute of Cancer Research, United Kingdom name: Imperial College London briefSummary: National Health Service (NHS) England has commissioned The Royal Marsden Hospital NHS Foundation Trust to run a novel mobile clinical outreach service called 'Man Van' with the aim of enabling male patients' easy access to care at the site of their work and in their communities. The initial focus of this new standard of care clinic is to access workplaces with large manual workforces where large scale working from home is not possible. These will include logistics firms and bus companies. These companies employ large numbers of black and minority ethnic men who also have poorer outcomes with a range of other diseases, including Coronavirus disease (COVID)-19. The novel clinical service will collaborate with Unite (and other unions) as well as employers in order to reach our target groups effectively. There is also the opportunity to target higher risk groups e.g. Afro Caribbean communities whose rates of prostate cancer are 1 in 41 as well as occupational higher risk categories. The Man Van has the potential to swing the balance of evidence in favour of Prostate-Specific Antigen (PSA) screening, with a targeted screening program directed at high-risk groups including ethnic minorities and manual workers. Reasons for poorer outcomes amongst these groups are multi-factorial and complex. Levels of education are often a factor which can impact the understanding of the disease and how to seek assistance. Distrust of medical organisations has also been cited as a factor.
The NHS sees many patients accessing cancer care at a late stage. Reducing this trend is a key objective of the NHS Long Term Plan. The COVID-19 pandemic has further exacerbated health inequalities and mobile clinics can potentially be a model for alleviating this. To enable patients access to medical treatment earlier there is a need to make the 'seeking advice on men's health and prostate issues' less daunting, more normal and easily accessible. The 'Man Van' has the ability to do just that and it is anticipated that the findings of this research, using the data generated from each patient's routine health screening, will demonstrate that a mobile outreach model is more effective in identifying cancers at an earlier stage than 'traditional' diagnostic pathways.
The reasons for high risk in prostate cancer are heavily linked to genetics. This is an issue as there is less recruitment of high risk groups to studies. We hope to gather genetic data from a higher proportion of genetically susceptible men via the Man Van, which can be used in future to further genetic knowledge of prostate cancer. conditions: Prostate Cancer conditions: Urologic Cancer conditions: Urologic Diseases conditions: Bladder Cancer conditions: Diabetes conditions: Hypertension conditions: Mental Health Issue conditions: Alcoholism conditions: Smoking conditions: Renal Cancer conditions: Testis Cancer studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 4000 type: ESTIMATED name: MV-POCT Sub-study name: Main Man Van Group Sub-study name: MV-QualQ Sub-study name: MV-PRS Sub-study name: MV-DNA and MV-UctDNA Sub-study name: Man Van patients measure: Cancer detection rates measure: Detection rates of other diseases sex: MALE minimumAge: 45 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Royal Marsden Hospital NHS Foundation Trust status: RECRUITING city: London zip: SW3 6JJ country: United Kingdom name: Ann Gandolfi role: CONTACT phone: 02086613903 email: ann.gandolfi@rmh.nhs.uk lat: 51.50853 lon: -0.12574 hasResults: False
nctId: NCT06357403 id: AntiXa-ICU 1881/2023 briefTitle: Association of Anti-factor Xa Activity With Venous Thromboembolism in Critically Ill Patients acronym: AntiXa-ICU overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-05 date: 2026-08 date: 2024-04-10 date: 2024-04-10 name: Medical University of Vienna class: OTHER briefSummary: The goal of this observational study is to analyse the association between anti-factor Xa activity (antiXa) and the occurence of venous thromboembolism (VTE; either deep vein thrombosis and/or pulmonary embolism) in critically ill patients who are admitted to an intensive care unit. The main questions it aims to answer are:
* How is the occurence of VTE related to patient-centred outcomes such as mortality, quality of life, length of stay and days outside of the intensive care unit/hospital. conditions: Thrombosis conditions: Pulmonary Embolism conditions: Enoxaparin studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 1300 type: ESTIMATED name: Anti-factor Xa activity calibrated for enoxaparin measure: Number of patients with new-onset venous thromboembolism measure: Number of patients with new-onset upper extremity deep vein thrombosis measure: Number of patients with new-onset lower extremity deep vein thrombosis measure: Number of patients with new-onset central vein thrombosis measure: Number of patients with new-onset symptomatic upper extremity deep vein thrombosis measure: Number of patients with new-onset symptomatic lower extremity deep vein thrombosis measure: Number of patients with new-onset incidental upper extremity deep vein thrombosis measure: Number of patients with new-onset incidental lower extremity deep vein thrombosis measure: Number of patients with new-onset pulmonary embolism measure: Number of patients with new-onset symptomatic pulmonary embolism measure: Number of patients with new-onset incidental pulmonary embolism measure: Number of patients with venous thromboembolism measure: Number of patients with deep vein thrombosis measure: Number of patients with pulmonary embolism measure: Number of patients with new-onset venous thromboembolism measure: Number of days with any bleeding measure: Number of days with major and/or fatal bleeding measure: Number of red blood cell concentrates administered measure: Number of days on which either procoagulant medication, platelet transfusion or fresh frozen plasma was administered measure: Length of stay in the intensive care unit measure: Length of stay in the hospital measure: Death measure: Days alive and out of the intensive care unit measure: Days alive and out of the hospital measure: European Quality of Life 5 Dimensions 5 Level Version (EQ-5D-5L) index value measure: European Quality of Life 5 Dimensions 5 Level Version (EQ-5D-5L) visual analogue scale sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06357390 id: 202106174RINB briefTitle: Physiologic and Clinical Effect of High-flow Oxygen Therapy in Tracheostomized Patients With Prolonged Mechanical Ventilation Undergoing Weaning Trials overallStatus: COMPLETED date: 2021-10-07 date: 2022-07-25 date: 2024-02-15 date: 2024-04-10 date: 2024-04-10 name: National Taiwan University Hospital class: OTHER briefSummary: This study is aimed at patients who have been admitted to the respiratory care center of this hospital who meet the PMV conditions (defined as continuous use of the ventilator for at least ten days) who are about to receive the ventilator out of training. After obtaining the explanatory consent, they will undergo continuous complete Before and after spontaneous breathing training, collect various relevant physiological data of lung volume and ventilation perfusion distribution, and analyze and predict the correlation of ventilator detachment. conditions: High Flow Oxygen Therapy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 10 type: ACTUAL measure: ventilation perfusion distribution measurement sex: ALL minimumAge: 20 Years stdAges: ADULT stdAges: OLDER_ADULT facility: National Taiwan University Hospital city: Taipei country: Taiwan lat: 25.04776 lon: 121.53185 hasResults: False
nctId: NCT06357377 id: NEO100-03 briefTitle: A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-10-31 date: 2024-10-31 date: 2024-04-10 date: 2024-04-10 name: Neonc Technologies, Inc. class: INDUSTRY briefSummary: This is an open label, Phase 1b safety, dose-finding, brain tumor delivery, and pharmacokinetics study of intranasal NEO100 in patients with pediatric-type diffuse high grade gliomas. Patients will receive IN NEO100 that will follow a dose titration design, followed by a standard dose escalation design to establish safety. Brain tumor delivery of NEO100 will be confirmed in each disease sub-type by surgical resection/needle biopsy only if clinically indicated and scheduled for clinical purposes and testing with residual tissue for NEO100 and the major metabolite of NEO100 (Perillic Acid). conditions: Pediatric Tumor of CNS conditions: Pediatric Tumor of Brain conditions: Diffuse Midline Glioma, H3 K27M-Mutant conditions: Pediatric Tumor of Brain Stem conditions: Pineocytoma conditions: Choroid Plexus Carcinoma, Childhood conditions: Spinal Cord Tumor conditions: High Grade Glioma studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 15 type: ESTIMATED name: NEO100 measure: Nature and severity of adverse events measure: Identify the maximum tolerated dose (MTD) of NEO100 measure: Determine the recommended Phase 2 dose (RP2D) of NEO100 measure: Measurement of NEO100 and its metabolite perillic acid in brain tumor tissue measure: Blood brain barrier penetration measure: Characterize the pharmacokinetics (PK) of NEO100 as measured by Peak Plasma Concentration measure: Characterize the pharmacokinetics (PK) of NEO100 as measured by the Time to Peak Plasma Concentration measure: Characterize the pharmacokinetics (PK) of NEO100 as measured by Area Under the Curve measure: To assess efficacy of NEO100 based on objective response rate (ORR). measure: To assess efficacy of NEO100 based on progression free survival (PFS). measure: To assess efficacy of NEO100 based on overall survival (OS). sex: ALL minimumAge: 5 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT hasResults: False
nctId: NCT06357364 id: CBT_Procrastination_Neuro briefTitle: Neural Changes Following Cognitive Behavior Therapy for Procrastination overallStatus: RECRUITING date: 2024-04-08 date: 2026-01-15 date: 2026-01-15 date: 2024-04-10 date: 2024-04-10 name: Nencki Institute of Experimental Biology of the Polish Academy of Sciences class: OTHER_GOV name: SWPS University of Social Sciences and Humanities name: Institute of Psychology, Polish Academy of Sciences briefSummary: The aim of this study is to compare the efficacy of and the neural changes following two cognitive behavior therapy (CBT) protocols for procrastination with a wait-list control group. The interventions will be delivered online in group settings. Both protocols include identical psychoeducation and cognitive modules aiming at identification and modification of dysfunctional automatic thoughts related to procrastination but will differ in the behavioral modules. The behavioral module in the first protocol is focused on timely beginning and realistic planning. The second protocol implements working time restriction. The wait-list control group will receive one of the CBT protocols after a waiting period that will last as long as the CBT intervention and the assessments performed directly after treatment. It is assumed that the interventions will be superior to the wait-list control. Primary (procrastination) and secondary (depression and anxiety) measures will be collected prior to and after the interventions (or waiting period in the wait-list group) and after 6 months in the two active condition groups. Additionally, neuroimaging measurements will be conducted before and after the interventions (or waiting period in the wait-list group). Approximately half of the participants will undergo functional Magnetic Resonance Imaging (fMRI), and another half will undergo electroencephalography (EEG). Both methods are aimed at exploring neural correlates of the expected improvements in participants' self-regulation abilities. conditions: Procrastination studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE maskingDescription: A researcher not having direct contact with participants will create a script generating random sequence using a computer random sequence generator (Matlab). Randomization will take place at an individual level, stratified by age, gender and procrastination severity (block randomization). Participants will be randomized into three groups with an allocation ratio of 1:1:1.
Pairs of experienced psychotherapists trained in one of the therapy protocols will deliver the interventions in an online group setting. whoMasked: PARTICIPANT count: 276 type: ESTIMATED name: Psychoeducation and cognitive modules name: Behavioral module: Starting on Time and Planning Realistically name: Behavioral module: Working Time Restriction measure: Change in Polish version of the Pure Procrastination Scale (PPS) measure: Change in Polish version of the Aitken Procrastination Inventory (API) measure: Change in Polish version of the Patient Health Questionnaire (PHQ-9) measure: Change in Polish version of the Generalized Anxiety Disorder Questionnaire-7 (GAD-7) measure: Percentage of completion of a particular project that the participant decided to work on during the training (e.g. a thesis, an essay, a report). measure: Change in Polish version of the Sensitivity to Punishment and Sensitivity to Reward Questionnaire - Short Form (SPSRQ-SF) measure: Change in Polish version of the Multidimensional-Multiattributional Causality Scale (MMCS) measure: Change in Polish version of the Performance Failure Appraisal Inventory (PFAI) measure: Change in Polish version of the Difficulties in Emotion Regulation questionnaire (DERS) measure: Change in Polish version of the Motivation Diagnostic Test (MDT) measure: Change in Polish version of the Zimbardo Time Perspective Inventory measure: Change in Polish version of the Metacognitive Beliefs about Procrastination Questionnaire (MBPQ) measure: Change in Polish version of the Impulsivity Scale (UPPS-P) measure: Change in Polish version of the Self-control Scale (NAS-50) measure: Change in Polish version of the Procrastination Diagnostic Criteria Questionnaires (PDCQ) measure: Change in Polish version of Positive and Negative Affect Schedule (PANAS) in relation to a project that the participant decided to work on during the training (e.g. a thesis, an essay, a report) measure: Polish version of the Group Session Rating Scale (GSRS) measure: Several items concerning homework compliance (cf. Kazantzis et al., 2005). measure: Polish version of the Credibility Expectancy Questionnaire (CEQ) measure: Polish version of the Negative Effects Questionnaire (NEQ) measure: Polish version of the Client Satisfaction Questionnaire (CSQ) measure: fMRI measurements measure: Electroencephalography (EEG) measurements sex: ALL minimumAge: 18 Years maximumAge: 26 Years stdAges: ADULT facility: Nencki Institute of Experimental Biology, Polish Academy of Sciences status: RECRUITING city: Warsaw zip: 02-093 country: Poland name: Marek Wypych, Phd, DSc role: CONTACT email: prokrastynacja@nencki.edu.pl lat: 52.22977 lon: 21.01178 hasResults: False
nctId: NCT06357351 id: VISTA in gingival recession briefTitle: Comparison of Using Collagen Membrane and A-PRF Using VISTA Technique in Gingival Recession Treatment overallStatus: ACTIVE_NOT_RECRUITING date: 2022-07-01 date: 2024-04 date: 2024-05 date: 2024-04-10 date: 2024-04-10 name: Mansoura University class: OTHER briefSummary: To assess the efficacy of minimally invasive Vestibular Incision Subperiosteal Tunnel Access (VISTA) with collagen membrane and Advanced Platelet-rich Fibrin (A-PRF) in the treatment of multiple buccal gingival recession type 1(RT1) Cairo Classification. conditions: Gingival Recession studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 24 type: ACTUAL name: vestibular incision sub periosteal tunnel access ( VISTA) technique. measure: Measuring the recession width in millimeter measure: Measuring the recession depth in millimeter measure: Measuring the width of keratinized gingiva in millimeter measure: Mean of root coverage measure: Measuring the probing depth measure: Measuring the plaque index measure: Measuring the gingival index measure: Clinical attachment level sex: ALL minimumAge: 18 Years maximumAge: 50 Years stdAges: ADULT facility: Mansoura university city: Mansoura country: Egypt lat: 31.03637 lon: 31.38069 hasResults: False
nctId: NCT06357338 id: Soh-Med-24-03-15MS briefTitle: Differential Expression and Potential Value of c-MYC in Non-Invasive and Invasive Mammary Carcinoma overallStatus: ENROLLING_BY_INVITATION date: 2024-03-19 date: 2025-04-01 date: 2026-04-01 date: 2024-04-10 date: 2024-04-10 name: Marwa Mahmoud Hassan class: OTHER name: Qena Oncology Center briefSummary: Retrospective observational study to evaluate c-MYC expression in non invasive and invasive mammry carcinoma conditions: Invasive Breast Cancer studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: RETROSPECTIVE count: 70 type: ESTIMATED name: no intervention measure: role of c-MYC in breast cancer sex: FEMALE minimumAge: 15 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Sohag university city: Sohag country: Egypt lat: 26.55695 lon: 31.69478 hasResults: False
nctId: NCT06357325 id: E-74555795-050.01.04-52290 briefTitle: 2023 Problems Faced by Women Earthquake Survivors in Kahramanmaraş overallStatus: COMPLETED date: 2023-06-22 date: 2023-09-30 date: 2023-12-01 date: 2024-04-10 date: 2024-04-10 name: Maltepe University class: OTHER briefSummary: Objective:
The study was designed in a qualitative type (semi-structured). The population of the study consisted of women affected by the 2023 Kahramanmaraş-Pazarcık earthquake. 15 women were interviewed. conditions: Psychosocial Problem conditions: Nurse-Patient Relations conditions: Disaster; Personality conditions: Gender studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 15 type: ACTUAL name: a qualitative study. measure: Personal Information Form measure: A semi-structured interview form measure: consists of questions about changes experienced after the earthquake sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Ozeninam city: Istanbul state: Maltepe zip: 34857 country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
nctId: NCT06357312 id: 2023/11P briefTitle: Influence of Static Distal Locking of a Short Proximal Femoral Nail overallStatus: RECRUITING date: 2024-04-01 date: 2024-04-01 date: 2024-04-01 date: 2024-04-10 date: 2024-04-10 name: Elda University Hospital class: OTHER briefSummary: Prospective, comparative, randomized, double-blind study to evaluate the outcomes of trochanteric nailing in unstable hip fractures with and without a distal interlocking screw. conditions: Hip Fracture studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Prospective, comparative, randomized and double-blind study primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Blinding of the patient included in the study and the investigator evaluating the results whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 200 type: ESTIMATED name: hip trochanteric nail measure: Evaluation of functional status using the Barthel index measure: Postoperative mechanical complications measure: Parker mobility scale sex: ALL minimumAge: 50 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Elda University Hospital status: RECRUITING city: Elda state: Comunidad Valenciana zip: 03600 country: Spain name: FRANCISCO ANTONIO MIRALLES MUÑOZ role: CONTACT phone: 651552115 email: fr_miralles@hotmail.com lat: 38.47783 lon: -0.79157 hasResults: False
nctId: NCT06357299 id: Pro00115060 briefTitle: Assessing Better Bottles for Babies acronym: AB3 overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2026-02-01 date: 2026-02-01 date: 2024-04-10 date: 2024-04-17 name: Duke University class: OTHER name: National Institutes of Health (NIH) briefSummary: This study will use a 2 x 2 factorial design to test impact of two intervention strategies (bottle size and bottle opacity) on infant weight gain. conditions: Pediatric Obesity conditions: Weight Gain Trajectory conditions: Infant Obesity studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: FACTORIAL interventionModelDescription: 2x2 factorial design primaryPurpose: TREATMENT masking: NONE count: 76 type: ESTIMATED name: Small Bottle Size name: Standard Bottle Size name: Clear Bottle name: Opaque Bottle measure: Conditional weight gain z-score changes (CWGz) measure: Formula volume per feed measure: Caregiver sensitivity to cues as measured by the Nursing Child Assessment Feeding Scale (NCAFS) sex: ALL minimumAge: 3 Days maximumAge: 1 Month stdAges: CHILD hasResults: False