hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06335823 id: STUDY20231621 briefTitle: Efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Reduction During Intrauterine Device (IUD) Insertion in Outpatient Gynecology overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-08-01 date: 2025-08-01 date: 2024-03-28 date: 2024-03-28 name: Jean Marino class: OTHER briefSummary: Pain with intrauterine device (IUD) insertion is very common and there are few options for patients to help reduce this pain. Transcutaneous electric nerve stimulators (TENS) are a non-invasive procedure that may help reduce the pain with IUD insertions. The investigators hope that the information gleaned from this study will result in pain control options for future patients who desire an IUD placement. conditions: IUD Insertion Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 60 type: ESTIMATED name: Transcutaneous electrical nerve stimulation (TENS) name: Placebo Transcutaneous electrical nerve stimulation (TENS) measure: Pain during IUD insertion as measured by the VAS score measure: Pain during IUD insertion as measured by the VAS score measure: Pain during IUD insertion as measured by the VAS score measure: Pain during IUD insertion as measured by the VAS score measure: Pain during IUD insertion as measured by the VAS score measure: Pain during IUD insertion as measured by the VAS score sex: FEMALE minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: University Hospitals city: Cleveland state: Ohio zip: 44106 country: United States name: Jean M Marino, APRN-CNP role: CONTACT phone: 440-720-3250 email: Jean.Marino@UHhospitals.org lat: 41.4995 lon: -81.69541 hasResults: False
nctId: NCT06335810 id: 23-10026599 id: R01DK135949-01 type: NIH link: https://reporter.nih.gov/quickSearch/R01DK135949-01 briefTitle: Reducing Obesity Using Social Ties Program acronym: ROBUST overallStatus: RECRUITING date: 2024-04-05 date: 2026-03 date: 2026-03 date: 2024-03-28 date: 2024-04-17 name: Weill Medical College of Cornell University class: OTHER name: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) briefSummary: This trial aims to test the feasibility and acceptability of addressing interpersonal barriers to weight-related behavior change. Specifically, the study will test if, by including up to two friends, family members, or co-workers in a lifestyle intervention for weight loss, the person enrolled in the study loses more weight than someone whose friends, family members, or co-workers were not invited to participate. conditions: Obesity studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: DOUBLE whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 264 type: ESTIMATED name: Social Network Intervention name: Individual Lifestyle Intervention name: Social Network Member measure: Number of participants who have attended at least 75 percent of the behavioral coaching sessions measure: Number of intervention participants who have at least one social network member engage in the study measure: Number of participants and social network members combined who complete the final study assessment measure: Change in positive communication and problem solving as measured by the McMaster Family Assessment Device (FAD) Questionnaire measure: Change in weight related social norms measure: Change in median Fitbit wear time in minutes measure: Change in total caloric amounts on three-day food record measure: Change in median number of days that the Fitbit is worn sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Weill Cornell Urology status: RECRUITING city: Brooklyn state: New York zip: 11217 country: United States name: Jesabely Solano, BS role: CONTACT phone: 646-962-9209 email: jes4037@med.cornell.edu lat: 40.6501 lon: -73.94958 facility: Weill Cornell Internal Medicine Associates status: RECRUITING city: New York state: New York zip: 10021 country: United States name: Jesabely Solano, BS role: CONTACT phone: 646-962-9209 email: jes4037@med.cornell.edu lat: 40.71427 lon: -74.00597 facility: Weill Cornell Primary Care at Lower Manhattan status: RECRUITING city: New York state: New York zip: 10038 country: United States name: Jesabely Solano, BS role: CONTACT phone: 646-962-9209 email: jes4037@med.cornell.edu lat: 40.71427 lon: -74.00597 facility: Weill Cornell Urology status: RECRUITING city: New York state: New York zip: 10065 country: United States name: Jesabely Solano, BS role: CONTACT phone: 646-962-9209 email: jes4037@med.cornell.edu lat: 40.71427 lon: -74.00597 hasResults: False
nctId: NCT06335797 id: IRB00110733 briefTitle: Optimization of Postoperative Bowel Habits overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-06 date: 2025-12 date: 2024-03-28 date: 2024-03-28 name: Wake Forest University Health Sciences class: OTHER briefSummary: Project is a trial, in which women undergoing vaginal surgery for pelvic organ prolapse will be randomized 1:1 to a postoperative bowel regimen of either oral senna or rectal bisacodyl suppository. conditions: Constipation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 88 type: ESTIMATED name: Senna Tab name: Dulcolax Suppositories measure: Time in hours to first bowel movement comparison between the two arms measure: Change in Overall Satisfaction (TSQM) Scores measure: Visual Analog Scale (VAS) Pain Scores measure: Patient Assessment of Constipation Symptom Questionnaire (PAC-SYM) Scores measure: Bristol Stool Form Scale (BSFS) Scores sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Wake Forest University Health Sciences city: Winston-Salem state: North Carolina zip: 27157 country: United States name: Christina M Mezes, MD role: CONTACT phone: 336-713-4098 email: cmezes@wakehealth.edu name: Sachin N Vyas, MS, PhD role: CONTACT phone: 336.713.4098 email: svyas@wakehealth.edu lat: 36.09986 lon: -80.24422 hasResults: False
nctId: NCT06335784 id: 2023-00456 briefTitle: Mental Imagery and Targeted Memory Reactivation in Insomnia overallStatus: RECRUITING date: 2024-04-22 date: 2027-05-31 date: 2027-08-31 date: 2024-03-28 date: 2024-04-23 name: University Hospital, Geneva class: OTHER name: University of Geneva, Switzerland briefSummary: In this clinical trial, the investigators test whether mental Imagery Rescripting (IR), a technique where the individual is instructed to transform a negative memory or image into a positive one, and olfactory Targeted Memory Reactivation (TMR), a technique used to strengthen memories, can reduce hyperarousal and insomnia severity in patients with Insomnia Disorder (ID).
Patients with ID will be randomized into four groups: in the first group (SH group), patients will have 4 weekly sessions (1 session/week) of a minimal intervention for insomnia (sleep hygiene information) in the presence of an odorless diffuser, which will be also used during the night. In the second group (IR group), patients will use IR during wakefulness to induce a state of relaxation and positive emotionality. More specifically, during 4 weekly sessions of IR, patients will imagine a negative scenario related to their pre-sleep images or current concerns (e.g., social interactions, self-image, sleep problem, nightmares) and transform it into a positive script. They will then perform IR every day for 4 weeks at home in the presence of an odorless diffuser, which will be also used during the night. In the third group, patients will undergo the same 4 weekly IR sessions and an odor will be paired to the positive imagery and will be diffused during the night (TMR group). Patients from this group will also perform IR every day for 4 weeks at home. Finally, the fourth group (OA group) will receive 4 weekly sessions of sleep hygiene instructions in the presence of an odor, which will be also used during the night.
The investigators hypothesize that patients treated with IR will have significantly reduced insomnia severity compared to participants who received a minimal intervention. They also hypothesize that patients of the TMR group, will have more reduced ID severity compared to participants performing IR and with an odorless diffuser, therefore without an association (IR group). Finally, they hypothesize that one night of sleeping in a rocking bed will improve objective measures of sleep in ID compared to a stationary condition. conditions: Insomnia Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 120 type: ESTIMATED name: Imagery Rescripting (IR) name: Imagery Rescripting (IR) and Targeted Memory Reactivation (TMR) during sleep name: Sleep Hygiene name: Sleep Hygiene + Odor name: "Rocking bed" if patients still have insomnia complaints (ISI >10) after the 4 weeks of the intervention measure: Insomnia Severity Index (ISI) measure: Pittsburgh sleep quality index (PSQI) measure: Total Sleep Time (TST) measure: Wake After Sleep Onset (WASO) measure: Beck Depression Inventory II (BDI-II) measure: State Trait Anxiety Inventory (STAI) measure: Sleep efficiency (SE) measure: Micro-arousals measure: Temperament and Character Inventory measure: Pre-sleep Arousal Scale (PSAS) measure: Arousal Predisposition Scale (APS) measure: Digit Span Task measure: Psychomotor Vigilance Task (PVT) measure: Declarative word paired-associate learning task measure: Attachment Style Questionnaire (ASQ) sex: ALL minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Center for Sleep Medicine status: RECRUITING city: Geneva country: Switzerland name: Lampros Perogamvros role: CONTACT phone: +41223729946 email: Lampros.Perogamvros@hcuge.ch name: Lampros Perogamvros role: PRINCIPAL_INVESTIGATOR lat: 46.20222 lon: 6.14569 hasResults: False
nctId: NCT06335771 id: 2098077 id: R01DK131188 type: NIH link: https://reporter.nih.gov/quickSearch/R01DK131188 briefTitle: Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity acronym: ATM overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2028-03 date: 2028-03 date: 2024-03-28 date: 2024-03-28 name: Bettina Mittendorfer class: OTHER name: National Institutes of Health (NIH) name: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) briefSummary: The goal of this study is to evaluate the role of transcription factor EB (TFEB) in adipose (fat) tissue macrophages (ATM) in regulating adipose tissue and systemic metabolic function in obesity. The investigators will assess the differences in ATM lipid metabolism in people with metabolically abnormal obesity and lean individuals.
* Overnight visit with intravenous infusion (IV), muscle, and fat tissue biopsies Participants with obesity will complete meetings with study team members for a weight loss intervention to achieve a 10% body weight loss. conditions: Obesity conditions: Nonalcoholic Fatty Liver conditions: Diabetes Type 2 conditions: Healthy studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: NONE count: 60 type: ESTIMATED name: Dietary consultation weight loss intervention measure: Insulin sensitivity assessed as insulin-mediated glucose disposal during a hyperinsulinemic-euglycemic clamp procedure. measure: 24-hour plasma glucose concentration measure: Macrophage isolation in adipose tissue biopsy measure: Macrophage isolation in skeletal muscle tissue sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Missouri School of Medicine city: Columbia state: Missouri zip: 65212 country: United States name: Bettina Mittendorfer role: CONTACT phone: 573-822-9377 email: b.mittendorfer@missouri.edu lat: 38.95171 lon: -92.33407 hasResults: False
nctId: NCT06335758 id: EXC-039-2023-CLR briefTitle: Non-randomized Observational Study to Evaluate ReX® in the Management of Solid Oral Medication. acronym: RegStud overallStatus: RECRUITING date: 2024-01-15 date: 2025-12-31 date: 2026-01-31 date: 2024-03-28 date: 2024-03-28 name: Dosentrx Ltd. class: INDUSTRY name: US Oncology Research briefSummary: The goal of this observational study is to evaluate the safety, efficacy and patient satisfaction with the ReX Remote Digital Nurse by patients receiving solid oral medication.
Patients participating in the study will receive their normal medication as standard of care via ReX. Progress will be monitored via patients' responses to questions presented on the ReX touch screen. conditions: Any Solid Oral Medication studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 1000 type: ESTIMATED name: Use of ReX to dispense and monitor solid oral medication therapy. measure: Treatment duration measure: Patient satisfaction measure: Adverse events measure: Patient adherence measure: Patient compliance measure: Patient engagement sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: OHC status: RECRUITING city: Cincinnati state: Ohio zip: 45242 country: United States name: Zachary Beck role: CONTACT lat: 39.12713 lon: -84.51435 hasResults: False
nctId: NCT06335745 id: 24-066 briefTitle: PediCARE Health Equity Intervention in High-Risk Neuroblastoma overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2028-04-01 date: 2030-04-01 date: 2024-03-28 date: 2024-03-28 name: Dana-Farber Cancer Institute class: OTHER briefSummary: This is a randomized Phase II trial evaluating the addition of the Pediatric Cancer Resource Equity (PediCARE) health equity intervention to usual supportive care for poverty-exposed children with newly diagnosed high-risk neuroblastoma.
* PediCARE + usual supportive care conditions: Neuroblastoma conditions: High-risk Neuroblastoma conditions: Pediatric Cancer conditions: Disparities conditions: Financial Stress conditions: Poverty studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 130 type: ESTIMATED name: PediCARE Intervention measure: Change in Kessler-6 Psychological Distress Scale Score measure: Proportion of Enrolled Participants (Feasibility) measure: Change in Mean Household Material Hardship (HMH) Score sex: ALL minimumAge: 0 Years maximumAge: 17 Years stdAges: CHILD facility: Boston Children's Hospital city: Boston state: Massachusetts zip: 02215 country: United States lat: 42.35843 lon: -71.05977 facility: Dana Farber Cancer Institute city: Boston state: Massachusetts zip: 02215 country: United States lat: 42.35843 lon: -71.05977 hasResults: False
nctId: NCT06335732 id: P.T.REC/012/004394 briefTitle: Prevalenc Of Lumbosacral Radiculopathy Among Physiotherapists Of Pediatric Rehabilitation OF PEDIATRIC REHABILITATION overallStatus: COMPLETED date: 2022-12-05 date: 2023-06-08 date: 2023-08-22 date: 2024-03-28 date: 2024-03-28 name: Kerolous Ishak Shehata class: OTHER briefSummary: Determine the prevalence of lumbosacral radiculopathy among pediatric physiotherapists in the ministry of health in Cairo, Egypt. conditions: Prevalence, Lumbosacral Radiculopathy studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: CROSS_SECTIONAL count: 200 type: ACTUAL name: Cross section study; single group related measurement design. measure: The Roland-Morris disability scale (RMS) measure: Straight Leg Raising (SLR) sex: ALL minimumAge: 25 Years maximumAge: 40 Years stdAges: ADULT facility: Kerolous Ishak Shehata city: Cairo country: Egypt lat: 30.06263 lon: 31.24967 hasResults: False
nctId: NCT06335719 id: IRB #22-926 briefTitle: Intraoperative Electrical Stimulation to Improve Nerve Grafting Outcome overallStatus: RECRUITING date: 2023-03-01 date: 2025-03 date: 2025-06 date: 2024-03-28 date: 2024-03-28 name: The Cleveland Clinic class: OTHER briefSummary: A research study to find out if brief intraoperative electrical stimulation therapy improves nerve regeneration and smile outcomes following two-stage cross face nerve graft facial reanimation surgery. conditions: Facial Paralysis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Patients will undergo all the standard steps of the facial reanimation procedures. The difference in care is 2/3 participants may receive the brief electrical stimulation therapy.
Other 1/3 of study participants will undergo the surgery as they normally would if they had not chosen to participate. primaryPurpose: TREATMENT masking: SINGLE maskingDescription: This is a randomized, controlled, double-blinded (patient and evaluator) prospective study. Plan is to enroll up to 30 patients, with a minimum of 20 completing full follow-up. Randomization 2:1 treatment to control due to previous peripheral nerve research demonstrating intraoperative stimulation accelerates axonal regeneration whoMasked: PARTICIPANT count: 20 type: ESTIMATED name: BES name: Standard of Care surgery measure: To evaluate efficacy of an intraoperative dose of brief electrical stimulation (BES) to improve axonal regeneration across a cross-face nerve graft (CFNG) using nerve histology. measure: To evaluate clinical outcomes of treatment and control groups using patient reported, and IRB approved CCF Facial Nerve Survey. sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Cleveland Clinic Foundation status: RECRUITING city: Cleveland state: Ohio zip: 44195 country: United States name: Hana Rosen, MD role: CONTACT phone: 216-444-7018 email: rosenh@ccf.org name: John O'Neill, BS role: CONTACT phone: 4405062611 email: oneillj2@ccf.org name: Patrick Byrne, MD role: PRINCIPAL_INVESTIGATOR name: Michael Fritz, MD role: SUB_INVESTIGATOR name: Brandon Hopkins, MD role: SUB_INVESTIGATOR name: Peter Ciolek, MD role: SUB_INVESTIGATOR name: Dane Genther, MD role: SUB_INVESTIGATOR name: Stephen Hadford, MD role: SUB_INVESTIGATOR name: Peng Ding, MD role: SUB_INVESTIGATOR name: Derek Vos, BS role: SUB_INVESTIGATOR lat: 41.4995 lon: -81.69541 hasResults: False
nctId: NCT06335706 id: 0596/66 briefTitle: The Influence of Fit of Underpants Worn on Semen Quality overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-05 date: 2024-05 date: 2024-03-28 date: 2024-03-28 name: Chulalongkorn University class: OTHER briefSummary: The goal of this observational study is to investigate the impact of underpants fit among Thai males attending the Infertility Clinic, whether alone or with their spouses. The main questions it aims to answer are:
The participants will need to provide informed consent, complete a questionnaire consisting of 28 questions, and provide a semen sample. conditions: Infertility, Male conditions: Semen Analysis studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 120 type: ESTIMATED name: Fit of underpants worn measure: Semen Volume measure: Total sperm count measure: Sperm concentration measure: Sperm motility measure: Sperm morphology measure: Sperm DNA integrity measure: Preferred type of underpants sex: MALE minimumAge: 20 Years maximumAge: 55 Years stdAges: ADULT hasResults: False
nctId: NCT06335693 id: CHHHospital briefTitle: Adjuvant Hypofractionated Radiotherapy for Prostate Cancer overallStatus: RECRUITING date: 2024-03-28 date: 2026-02-28 date: 2027-02-28 date: 2024-03-28 date: 2024-03-28 name: Changhai Hospital class: OTHER briefSummary: Hypofractionated radiation therapy is a new type of radiotherapy which has been shown to play a larger role in the treatment of prostate cancer. The aims of the trial were to evaluate the safety and feasibility of adjuvant hypofractionated radiotherapy following radical prostatectomy for prostate cancer. conditions: Prostate Cancer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 9 type: ESTIMATED name: Radiotherapy measure: Incidence of radiotherapy-related gastrointestinal and genitourinary adverse events measure: progression-free survival (PFS) measure: medical expenses measure: quality of life(QoL) measure: overall survival (OS) measure: prostate cancer-specific survival (CSS) sex: MALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The First Affiliated Hospital of Naval Medical University status: RECRUITING city: Shanghai state: Shanghai zip: 200433 country: China name: Huojun Zhang, PhD role: CONTACT phone: 021-31162222 email: huojunzh@163.com lat: 31.22222 lon: 121.45806 hasResults: False
nctId: NCT06335667 id: 4565 id: UCI 23-72 type: OTHER domain: UCI CFCCC briefTitle: mpMRI Compared to Diagnostic TURBT in Patients With Suspected Muscle-Invasive Bladder Cancer Objectives overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-04 date: 2030-04 date: 2024-03-28 date: 2024-03-28 name: University of California, Irvine class: OTHER briefSummary: This is a pilot, single arm, prospective study that aims to validate the accuracy of the VI-RADS score obtained via multi-parametric magnetic resonance imaging (mpMRI) compared to pathologic cancer stage obtained via diagnostic transurethral bladder tumor resection (TURBT) as well as compare the clinical and quality of life outcomes between these diagnostic modalities in patients with suspected muscle-invasive bladder cancer (MIBC). conditions: Urothelial Bladder Cancer conditions: Muscle-Invasive Bladder Cancer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: DIAGNOSTIC masking: NONE count: 30 type: ESTIMATED name: mpMRI + Diagnostic TURBT measure: Incidence of concordance between VI-RADS score of 4 or 5 (i.e. muscular propria is likely or very likely) on mpMRI and pathologic muscularis propria invasion (i.e. pT2 tumor stage) on diagnostic TURBT. measure: Progression free survival (PFS) with mpMRI compared to diagnostic TURBT measure: Time from intervention that determines invasiveness of bladder tumors (i.e. diagnostic TURBT versus mpMRI) to initiation of cancer-directed therapy measure: Time from initial cystoscopy to intervention that determines invasiveness of bladder tumors (i.e diagnostic TURBT versus mpMRI). measure: Incidence of adverse events with mpMRI versus diagnostic TURBT. measure: Patient Quality of Life with mpMRI versus diagnostic TURBT. measure: Incidence of repeat TURBT. measure: Diagnostic healthcare expenditure with mpMRI versus diagnostic TURBT sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Chao Family Comprehensive Cancer Center University of California, Irvine city: Orange state: California zip: 92868 country: United States name: Nataliya Mar, MD role: CONTACT phone: 877-827-8839 email: ucstudy@uci.edu lat: 33.78779 lon: -117.85311 hasResults: False