hackint0sh/New-Dataset huggingface dataset:
nctId: NCT06357117 id: A01263 briefTitle: Extent of Intrahepatic Infiltration of Perihilar Cholangiocarcinoma overallStatus: COMPLETED date: 2018-04-13 date: 2021-12-22 date: 2021-12-22 date: 2024-04-10 date: 2024-04-11 name: Beijing Tsinghua Chang Gung Hospital class: OTHER briefSummary: The extent of intrahepatic infiltration of perihilar cholangiocarcinoma (PHCC) remains unclear. This research aimed to explore the pattern and extent of intrahepatic infiltration of PHCC to guide surgical treatment and pathological research. This prospective study included 62 participants diagnosed with PHCC who underwent major hepatectomy. A whole-mount digital liver pathology system (WDLPS) for hepatectomy specimens greater than 10 × 10 cm was used to panoramically assess the intrahepatic infiltration extent of PHCC. conditions: Perihilar Cholangiocarcinoma studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 62 type: ACTUAL measure: Relapse-free survival (RFS). measure: Overall survival (OS). sex: ALL minimumAge: 44 Years maximumAge: 81 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Beijing Tsinghua Chang Gung Hospital city: Beijing state: Beijing zip: 102218 country: China lat: 39.9075 lon: 116.39723 hasResults: False
nctId: NCT06357104 id: SCI-CT-0001 briefTitle: Detoxification From the Lipid Tract overallStatus: COMPLETED date: 2024-02-26 date: 2024-03-14 date: 2024-03-20 date: 2024-04-10 date: 2024-04-10 name: Pachankis, Yang I., M.D. class: INDIV name: First Affiliated Hospital of Chongqing Medical University briefSummary: Apart from electroencephalogram biofeedback and electrical brain stimulation adopted for maintenance treatment, the study utilizes ultra-low frequency transcranial magnetic stimulation (ULF-TMS) for initial γ-aminobutyric acid (GABA) stimulation. The cocktail therapy starts after the primary efficacy endpoint, and concomitant therapy is adopted throughout the study. conditions: COVID-19 Vaccine Adverse Reaction studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 1 type: ACTUAL name: electroencephalogram biofeedback name: electrical brain stimulation name: ultra-low frequency transcranial magnetic stimulation name: Sertraline Hydrochloride name: Clonazepam name: Alprazolam name: Metoprolol name: Olanzapine name: Pravastatin Sodium 20 MG name: Sacubitril Valsartan Sodium Hydrate measure: Changes in Leukocyte and Components' Quantities measure: Changes in Leukocyte Components' Ratios measure: Quantity Changes in Megakaryocyte-Erythroid Progenitor measure: Changes in Hemoglobin Distribution measure: Changes in Mean Corpuscular Hemoglobin measure: Changes in Hematocrit measure: Changes in Plateletcrit measure: Red cell Distribution Width Coefficient of Variation measure: Changes in Particulate Matter Sizes measure: Changes in Total Lipid Quantities measure: Changes in Apolipoproteina measure: Changes in Lipoprotein (a) measure: Blood Pressure Changes measure: Heart Rate Changes sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Residential Address city: Chongqing state: Chongqing zip: 402762 country: China lat: 29.56278 lon: 106.55278 typeAbbrev: Prot_ICF hasProtocol: True hasSap: False hasIcf: True label: Study Protocol and Informed Consent Form date: 2024-03-07 uploadDate: 2024-03-15T00:02 filename: Prot_ICF_000.pdf size: 479591 hasResults: False
nctId: NCT06357091 id: 1097/2023 ACL-Shark Screw® briefTitle: ACL Reconstruction With Shark Screw® or Biocomposite-interference Screws overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2031-06-01 date: 2031-06-01 date: 2024-04-10 date: 2024-04-25 name: Bezirkskrankenhaus Schwaz class: OTHER briefSummary: The goal of this clinical trial is to compare the outcome of 2 different screws for Anterior cruciate ligament reconstruction. The main question is if the human allogeneic cortical bone screw reduces tunnel widening in comparison to conventional treatment with a biocomposite screw. Additional the re-rupture rate will be evaluated and knee scores will be recorded before surgery and after surgery. Participants will have MRI before and after surgery, 3, 6, 12, and 24 months after surgery and Computertomography after surgery, 3, 6 and 24 months after surgery. Questionnaires (Knee-scores) will be recorded before surgery, 6, 12, 24 months after surgery.
the investigators hope that with the human cortical bone screw the tunnel widening is reduced and the re-rupture rate is low conditions: Anterior Cruciate Ligament Rupture conditions: Anterior Cruciate Ligament Reconstruction conditions: Anterior Cruciate Ligament Injury studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 80 type: ESTIMATED name: ACL reconstruction with Shark Screw ACL® name: ACL reconstruction with biocomposite screw (Mecta) measure: bone tunnel widening will be measured by CT and/or MRI and measured in mm measure: International Knee Documentation Committee (IKDC) Scores measure: Knee Injury and Osteoarthritis Outcome Score (KOOS) Scores measure: Lysholm Knee Score measure: Tegner Activity Score sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Bezirkskrankenhaus Schwaz Betriebsgesellschaft m.b.H. city: Schwaz state: Tirol zip: 6130 country: Austria name: Alexander Rofner-Moretti, MD role: CONTACT phone: +435242 phoneExt: 600 email: alexander.rofner-moretti@kh-schwaz.at name: Markus Reichkendler, MD role: CONTACT phone: +435242 phoneExt: 600 email: markus.reichkendler@kh-schwaz.at lat: 47.35169 lon: 11.71014 facility: Bezirkskrankenhaus Schwaz Betriebsgesellschaft m.b.H city: Schwaz state: Tirol zip: 6130 country: Austria name: Alexander Rofner-Moretti, MD role: CONTACT phone: +435242600 email: alexander.rofner-moretti@kh-schwaz.at name: Markus Reichkendler, MD role: CONTACT phone: +435242600 email: markus.reichkendler@kh-schwaz.at name: Alexander Rofner-Moretti, MD role: PRINCIPAL_INVESTIGATOR name: Markus Reichkendler, MD role: SUB_INVESTIGATOR name: Boris Tirala, MD role: SUB_INVESTIGATOR name: Martin Wallner, MD role: SUB_INVESTIGATOR name: Lukas Pöhl, MD role: SUB_INVESTIGATOR name: Samuel Dolling, MD role: SUB_INVESTIGATOR name: Edith Reches, MD role: SUB_INVESTIGATOR name: Clemens Lottersberger, MD role: SUB_INVESTIGATOR lat: 47.35169 lon: 11.71014 hasResults: False
nctId: NCT06357078 id: AmasyaU-NU-679 briefTitle: Art Therapy and Caregivers Stress overallStatus: RECRUITING date: 2024-01-02 date: 2024-06-28 date: 2024-07-31 date: 2024-04-10 date: 2024-04-16 name: Amasya University class: OTHER briefSummary: This research will be conducted to determine the effect of art therapy on the stress, anxiety and well-being of caregivers in the palliative care service. conditions: Caregiver Stress Syndrome studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 52 type: ESTIMATED name: Art Therapy measure: Distress Thermometer measure: The State Anxiety Inventory measure: Personal Well-Being Index sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Neşe Uysal status: RECRUITING city: Amasya zip: 0500 country: Turkey name: Neşe Uysal role: CONTACT phone: (90)3582181767 email: uysaln2007@hotmail.com lat: 40.65333 lon: 35.83306 hasResults: False
nctId: NCT06357065 id: UCatolicaMaule id: 11240343 type: OTHER_GRANT domain: ANID Chile briefTitle: Active Transport Educational Program Based on the Ecological Model on Improving the Physical and Mental Health: MOV-ES Project acronym: MOV-ES overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-12-20 date: 2026-12-20 date: 2024-04-10 date: 2024-04-10 name: Universidad Católica del Maule class: OTHER briefSummary: The epidemic of physical inactivity affects the entire world and is responsible for more than 5 million deaths per year. The call of the United Nations, through the 2030 Agenda and the Sustainable Development Goals, encourages the creation of favorable environments for physical activity based on the ecological model of physical activity. Given this context, active transportation can be an accessible, economical, and sustainable method to increase daily physical activity. The rate of school children who use active transport has decreased, being replaced by motorized transport, causing congestion and high levels of pollution in cities. In the Chilean context, there are studies of active transportation in the Chilean population; however, they are scarce in the school population and none of them is an intervention study, demonstrating the incipient development of this area in the country. The benefits of promoting active transportation not only favor the lifestyles of school children but also include additional co-benefits such as the improvement of mental health and better academic performance, in addition to the reduction of exhaust and greenhouse gas emissions.
Objectives. This proposal consists of three phases with the following objectives: Phase I: i) to synthesize the evidence about interventions aimed at estimating the effect on health of active transport in the secondary students; and ii), using qualitative techniques, to explore, from the basis of grounded theory, barriers and facilitators perceived by professors, students and parents about the development and implementation of the MOV-ES intervention. Phase II. Pilot and feasibility trial: a) to test the effect of MOV-ES intervention on improving body composition (body fat percentage and muscle mass), physical fitness (aerobic capacity and muscular strength), executive function and mental fitness (mood disorders, cognitive functioning) in the secondary students; and b), to examine the acceptability by professors, parents and students of the intervention by using ad hoc questionnaires. Phase III: to test the effectiveness of the MOV-ES intervention on physical activity, physical fitness, cognition and mental health through a cluster randomized controlled trial.
Expected results: This project will give rise to the following master\'s and doctoral theses, with their corresponding articles of high scientific impact: 1) Barriers and facilitators of teachers, parents and students for active transport from a qualitative approach; 2) Association between the built environment, urban features, and active transportation in high school students, 3) Effectiveness of an active transportation educational intervention on physical fitness and body composition, 4) Effectiveness of an active transportation educational intervention on the cognition of schoolchildren. It is expected that the results of the MOV-ES Project will transcend the physical health of schoolchildren and will have an impact on the school community, especially by decongesting the school environment. Through these results, the Ministry of Education, regional DAEM, municipalities, and educational establishments will be able to propose public policies that favor the practice of physical activity and the acquisition of healthy habits at school age. All of the above is based on quality indicators proposed by the Education Quality Agency. conditions: Physical Inactivity in Children studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Study design, setting: This is a cluster randomized field trial aimed to evaluate the previously tested MOV-ES intervention.
Population: First year of high school students in a city in south-central Chile. Three secondary schools in the urban area of Talca (1 public, 1 private subsidized, and 1 private non-subsidized) with at least three classes per school year will be randomly selected. This methodological option was adopted because, in Chile, school administration is associated with the socioeconomic level of families. primaryPurpose: PREVENTION masking: SINGLE maskingDescription: Randomization and blinding procedures: We invited 6 first-year high school classes to participate and, using a computer-generated procedure, will be randomized to the IG and to CG. The participants will be informed of the result of randomization after they agreed to participate in the study. The nature of the intervention makes its blinding infeasible. whoMasked: INVESTIGATOR count: 180 type: ESTIMATED name: Active transport educational program based on the ecological model measure: Body composition change (fat mass) by bioimpedance at 16 weeks measure: Change from Body Composition (fat-free mass) by bioimpedance at 16 weeks measure: Changes in Executive Function (inhibition) at 16 weeks measure: Changes in Executive Function (cognitive flexibility) at 16 weeks measure: Changes in executive function (working memory) at 16 weeks measure: Change from Anthropometric measurements at 16 weeks measure: Changes in objective physical activity at 16 week measure: Change from Physical Fitness (Aptitud cardiorrespiratoria (VO2 máx) at 16 weeks measure: Change from Physical Fitness (lower body strength) at 16 weeks measure: Change from Physical-Functional Fitness (strenght on the upper body) at 16 weeks measure: Change from mental health (depression) at 16 weeks measure: Change from mental health (Anxiety) at 16 weeks measure: Change from mental health (Stress) at 16 weeks measure: Changes in overall academic performance once the intervention is completed measure: Changes in health-related quality of life at 16 weeks measure: Changes in the Perception of urban environmental characteristics at 16 weeks measure: Changes in physical activity barriers at 16 weeks measure: Changes in adherence to physical activity at 16 weeks measure: Changes in the form of Transportation to and from School (Active Transportation) at 16 weeks. measure: Sociodemographic evaluations of parents measure: Parents' perception of urban environmental characteristics measure: Parents' perception of physical fitness sex: ALL minimumAge: 14 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06357052 id: 2701 briefTitle: The Study of Lithogenesis Processes in Patients With Non-alcoholic Fatty Liver Disease (NAFLD) acronym: LINA overallStatus: COMPLETED date: 2019-07-19 date: 2022-04-30 date: 2022-11-30 date: 2024-04-10 date: 2024-04-10 name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS class: OTHER briefSummary: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease, ranging from pure steatosis to non-alcoholic steatohepatitis and ultimately to liver cirrhosis. In order to study the association between NAFLD and nephrolithiasis while minimizing the confounding effect of metabolic syndrome, we investigated the impact of different degrees of NAFLD severity on potential risk factors for stone formation. conditions: NAFLD conditions: Urinary Lithiasis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 42 type: ACTUAL measure: the analysis of the correlation between the degree of severity of NAFLD And urinary lithogenic profilecharacterized by reduced urinary magnesium and altered urinary ammonium excretion. sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Fondazione Policlinico A.Gemelli IRCCS city: Roma zip: 00168 country: Italy lat: 41.89193 lon: 12.51133 hasResults: False
nctId: NCT06357039 id: 09.2023.422 id: 2220124 type: OTHER_GRANT domain: Scientific and Technological Research Council of Türkiye (TÜBİTAK) id: 1065371 type: OTHER_GRANT domain: Small and Medium Enterprises Development Organization (KOSGEB) briefTitle: Validation Study of Sleep Tracking Devices overallStatus: COMPLETED date: 2023-03-21 date: 2023-05-31 date: 2023-07-17 date: 2024-04-10 date: 2024-04-25 name: PNAPS Health Informatics and Space Technologies Inc. class: OTHER name: Analog Devices briefSummary: In this study, a two-part recursive convolutional neural networks model was developed, extracting features for each epoch window independently from before and after sleep onset (epoch encoder), and then trained in the context of long-term relationships in the sleep process (sequence encoder), using an approach similar to human expert classification based on information from single-channel forehead EEG and PPG (IR, Green, Red). The classification is based on guidelines from the American Academy of Sleep Medicine and calculated six parameters: total sleep duration (TST), wake (W), N1, N2, N3, and REM.
The validation study of the developed model and the device was conducted at the Sleep Disorders Centre of the Istanbul Medical Faculty using concurrent polysomnographic data from 305 male and female patients aged 18 to 65 years. conditions: Sleep conditions: Sleep Disorder studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: CROSS_SECTIONAL count: 305 type: ACTUAL name: Sleep tracking device measure: Sleep Stages Classification Accuracy measure: Interoception analysis from PPG data collected from facial skin sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Pnaps Health Informatics and Space Technologies Inc city: Istanbul state: Başıbüyük, Maltepe zip: 34854 country: Turkey lat: 41.01384 lon: 28.94966 typeAbbrev: Prot hasProtocol: True hasSap: False hasIcf: False label: Study Protocol date: 2023-03-09 uploadDate: 2024-04-04T08:32 filename: Prot_000.pdf size: 55944 typeAbbrev: ICF hasProtocol: False hasSap: False hasIcf: True label: Informed Consent Form date: 2023-03-09 uploadDate: 2024-04-04T04:55 filename: ICF_001.pdf size: 78393 hasResults: False
nctId: NCT06357013 id: 2023-40 briefTitle: Postoperative Analgesia in Bilateral Knee Arthroplasties overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-01 date: 2024-05-01 date: 2024-05-30 date: 2024-04-10 date: 2024-04-10 name: Kocaeli City Hospital class: OTHER_GOV briefSummary: To observationally compare the analgesic efficacy of LIA and S-FICB techniques and to record the pain scores of patients who underwent bilateral knee operations in the postoperative period. conditions: Knee Arthroplasty, Total conditions: Peripheral Nerve Block conditions: Pain, Postoperative studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 60 type: ESTIMATED name: Bilateral Suprainguinal fascia iliaca compartment block name: Local infiltration analgesia measure: Suprainguinal fascia iliaca compartment block (S-FICB) produces adequate analgesic effect in knee arthroplasty. sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Kocaeli City Hospital city: Kocaeli country: Turkey lat: 39.62497 lon: 27.51145 hasResults: False
nctId: NCT06357000 id: Time from PCI to surgery briefTitle: Time From PCI to Cancer Surgery and Cardiovascular and Oncologic Outcomes overallStatus: COMPLETED date: 2008-01-01 date: 2018-12-31 date: 2018-12-31 date: 2024-04-10 date: 2024-04-10 name: Samsung Medical Center class: OTHER briefSummary: To evaluate the association between time from PCI to cancer surgery and cardiovascular and oncologic outcomes in early-stage cancer patients, A retrospective, population-based cohort study was conducted using data from the Korean National Health Insurance Service (K-NHIS) database. conditions: Coronary Artery Disease conditions: Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 3621 type: ACTUAL measure: Occurence of Bleeding measure: Occurence of Spontaneous myocardial infarction measure: Occurence of Repeat revascularization measure: Occurence of Cancer recurrence measure: Occurence of All cause death sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06356987 id: 0002 briefTitle: Comparison of Laparoscopic Herniotomy and Open Herniotomy in Children acronym: Herniotomy overallStatus: COMPLETED date: 2021-06-01 date: 2021-12-31 date: 2021-12-31 date: 2024-04-10 date: 2024-04-12 name: King Edward Medical University class: OTHER briefSummary: All patients of age 6 month to 12 years with inguinal hernia were included in study.
Data was collected on detailed proforma regarding age, sex, side ,operative time, cosmesis , and postoperative complications conditions: Inguinal Hernia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: 66 patients with inguinal hernia were randomly divided into two groups (A and B) primaryPurpose: TREATMENT masking: NONE maskingDescription: 66 patients (33 patients in each group) of laparoscopic extraperitoneal closure and open herniotomy each count: 66 type: ACTUAL name: Herniotomy measure: Operative time measure: Recurrence sex: ALL minimumAge: 6 Months maximumAge: 12 Years stdAges: CHILD facility: Muhammad Sharif city: Lahore state: Punjab zip: 53711 country: Pakistan lat: 31.558 lon: 74.35071 hasResults: False
nctId: NCT06356974 id: STROgHAT briefTitle: Stop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT) acronym: STROgHAT overallStatus: NOT_YET_RECRUITING date: 2024-04-08 date: 2026-12-30 date: 2027-12-30 date: 2024-04-10 date: 2024-04-10 name: Drugs for Neglected Diseases class: OTHER name: Institute of Tropical Medicine, Belgium name: Institut de Recherche pour le Developpement name: Institut National de Recherche Biomédicale. Kinshasa, République Démocratique du Congo name: Ministry of Public Health, Democratic Republic of the Congo briefSummary: This protocol describes both the epidemiological study which aims at assessing whether over a three-year period a zero prevalence can be achieved when implementing a screen \& treat approach with acoziborole, as well as a nested clinical study aimed at generating further evidence on safety of acoziborole in gambiense human African trypanosomiasis (gHAT) seropositives individuals. The overall coordinator will be ITM. ITM will be fully responsible for the epidemiological study (study Part A), including cost effectiveness and evaluation of diagnostic tests. DNDi will be the legal sponsor of the nested safety clinical study (study Part B) and will ensure compliance with regulatory requirements and good clinical practices (GCP) for this part of the study.
The objectives are to evaluate whether a strategy based on widened treatment for all parasitologically negative seropositive gHAT suspects with acoziborole can lead to interruption of transmission of T.b.gambiense in a mainland focus and to assess the safety of acoziborole in gHAT seropositve individuals and parasitologically negative. conditions: Human African Trypanosomiasis studyType: INTERVENTIONAL phases: PHASE3 allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: one-arm, open label, non-randomized, multicentre, phase IIIb study primaryPurpose: TREATMENT masking: NONE count: 2500 type: ESTIMATED name: Treatment of seropositive individuals (positive serology test, but parasitology not confirmed) measure: Interruption of transmission of T.b. gambiense measure: Assessment of safety measure: Economic evaluation measure: assessment of the performance of several diagnostic tests sex: ALL minimumAge: 11 Years stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
nctId: NCT06356961 id: 2022Z4BB82 id: 2022Z4BB82 type: OTHER_GRANT domain: Decreto Direttoriale n. 901 SH4(MUR-PRIN 2022) briefTitle: Routine Outcome Monitoring and Feedback Informed Therapy in Italy acronym: FIT-ITALY overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2024-12-31 date: 2025-10-05 date: 2024-04-10 date: 2024-04-10 name: University of Bergamo class: OTHER name: University of Palermo name: Politecnico di Milano name: Leiden University name: University of Ottawa name: University of Sheffield name: Brigham Young University briefSummary: The research project OutProFeed - Italy: Routine outcome monitoring and feedback informed therapy in Italy: 1st Italian RCT large population study, represents the first Italian randomised controlled trial (RCT) to evaluate the effectiveness of feedback-informed psychotherapy (FIT) to improve patients mental health outcomes and psychotherapy processes through the use of the digital platform Mindy.