Question: Centocor is a unit of a company founded in which year ?

full_context: Document 1: Biological response modifiers: Biological response modifiers (BRMs) are substances that modify immune responses. They can be both endogenous (produced naturally within the body) and exogenous (as pharmaceutical drugs), and they can either enhance an immune response or suppress it. Some of these substances arouse the body's response to an infection, and others can keep the response from becoming excessive. Thus they serve as immunomodulators in immunotherapy (therapy that makes use of immune responses), which can be helpful in treating cancer (where targeted therapy often relies on the immune system being used to attack cancer cells) and in treating autoimmune diseases (in which the immune system attacks the self), such as some kinds of arthritis and dermatitis. Most BRMs are biopharmaceuticals (biologics), including monoclonal antibodies, interleukin 2, interferons, and various types of colony-stimulating factors (e.g., CSF, GM-CSF, G-CSF). "Immunotherapy makes use of BRMs to "enhance" the activity of the immune system to increase the body's natural defense mechanisms against cancer", whereas BRMs for rheumatoid arthritis aim to reduce inflammation.
Document 2: 2010 Johnson &amp; Johnson children's product recall: 2010 Johnson &amp; Johnson children's product recall
Document 3: Janssen Biotech: Janssen Biotech, Inc., formerly Centocor Biotech, Inc., is a biotechnology company that was founded in Philadelphia in 1979 with an initial goal of developing new diagnostic assays using monoclonal antibody technology.
Document 4: Jones Pharma: Jones Pharma is a specialty pharmaceuticals manufacturer and marketer based in St. Louis, Missouri. The company was founded on March 16, 1981 by Dennis M. Jones and Judith Pearce Jones under the name Jones Medical Industries. The company completed its initial public offering in 1986, trading under the ticker symbol JMED on the NASDAQ. The primary therapeutic compounds marketed by the company include Thrombin-JMI and Levoxyl On May 30, 2000 the company became a wholly owned subsidiary of King Pharmaceuticals (NYSE:KG), based in Bristol, Tennessee. The market value of the company on its closing trade was $3.6 billion. Parent company King Pharmaceuticals was acquired by Pfizer in 2010.
Document 5: Patterson Companies: Patterson Companies Inc is a medical supplies conglomerate primarily in the business of veterinary and dental products (ranging from xray equipment to consumable products, dental consumables make up the biggest part of the dental industry). Since 2003 it also distributes general medical rehabilitative devices like braces and wheel chairs. Traditionally a dental company it diversified its business at the turn of the millennium when it acquired 55-year-old company JA Webster Inc, a distributor of veterinary products. That business segment (now known as Patterson Veterinary) currently distributes equipment (diagnostic and surgical) and medicine (anaesthetics, vaccines). The company operates directly in only the US and Canada (in Canada through subsidiaries Sammons Preston Canada and Patterson Dental Canada).
Document 6: Alefacept: Alefacept is a genetically engineered immunosuppressive drug. It was sold under the brand name Amevive in Canada, the United States, Israel, Switzerland and Australia. In 2011, the manufacturers made a decision to cease promotion, manufacturing, distribution and sales of Amevive during a supply disruption. According to Astellas Pharma US, Inc. (https://www.psoriasis.org/media/press-releases/amevive-alefacept-voluntarily-discontinued-us), the decision to cease Amevive sales was neither the result of any specific safety concern nor the result of any FDA-mandated or voluntary product recall. On the other hand, usage of Amevive was associated with a certain risk of development systemic diseases such as malignancies. This drug was never approved for the European drug market.
Document 7: NIH Intramural Research Program: The NIH Intramural Research Program (IRP) is the internal research program of the National Institutes of Health (NIH), known for its synergistic approach to biomedical science. With 1,200 Principal Investigators and over 4,000 Postdoctoral Fellows conducting basic, translational, and clinical research, the NIH Intramural Research Program is the largest biomedical research institution on earth. The unique funding environment of the IRP facilitates opportunities to conduct both long-term and high-impact science that would otherwise be difficult to undertake. With rigorous external reviews ensuring that only the most outstanding research secures funding, the IRP is responsible for many scientific accomplishments, including the discovery of fluoride to prevent tooth decay, the use of lithium to manage bipolar disorder, and the creation of vaccines against hepatitis, Hemophilus influenzae (HIB), and human papillomavirus (HPV). In addition, the IRP has also produced or trained 21 Nobel Prize-winning scientists.
Document 8: Johnson &amp; Johnson: Johnson & Johnson is an American multinational medical devices, pharmaceutical and consumer packaged goods manufacturing company founded in 1886. Its common stock is a component of the Dow Jones Industrial Average and the company is listed among the Fortune 500.
Document 9: Innerstate: Innerstate is a 2007 documentary film on the "inner states" of three adults living with chronic diseases of the immune system: psoriasis, Crohn's disease, and rheumatoid arthritis. The film was produced and directed by Chris Valentino and was funded by Centocor Inc., a biomedicines company. According to the "New York Times", the film is "an unusual form of soft-peddle marketing of a blockbuster drug, Remicade". Remicade (Infliximab) is a medication used to treat autoimmune diseases made by Centocor, a unit of Johnson & Johnson.
Document 10: Johnson Financial Group: Johnson Financial Group, Inc is the holding company of Johnson Bank, Johnson Insurance, as well as Swiss banking company; Banque Franck, Galland & Cie. It has an estimated AUM of $4 billion and is the financial services subsidiary of the larger Johnson Family Enterprises Group of Companies. The company was founded in 1970 but wasn't incorporated until 1989 and has grown from a single bank holding company to a global organization providing a full range of financial services to businesses and individuals. Johnson Financial Group employs 1100 people and has over 40 locations in Wisconsin and Arizona. Helen Johnson-Leipold, one of Samuel Curtis Johnson Jr.'s 4 children, serves as chairman of the company. The company also had equity in Cayman Island-based TransOcean Bank & Trust, Ltd.
Document 11: Serum Institute of India: Serum Institute of India is a manufacturer of immunobiological drugs including vaccines in India. The company is managed by the Poonawalla group which fully owned by Cyrus Poonawalla. The company was founded by Poonawalla in 1966. It is the world's largest vaccine producer by number of doses produced. The company is developing an intra-nasal swine flu vaccine. Co-developed with US-based Mass Biologics of the University of Massachusetts Medical School, it invented a fast-acting anti-rabies agent, Rabies Human Monoclonal Antibody (RMAb).
Document 12: Fortune 500: The Fortune 500 is an annual list compiled and published by "Fortune" magazine that ranks 500 of the largest United States corporations by total revenue for their respective fiscal years. The list includes publicly held companies, along with privately held companies for which revenues are publicly available. The concept of the Fortune 500 was created by Edgar P. Smith, a "Fortune" editor, and the first list was published in 1955. The Fortune 500 is more commonly used than its subset Fortune 100 or wider list Fortune 1000.
Document 13: Inside Job (2010 film): Inside Job is a 2010 documentary film, directed by Charles H. Ferguson, about the late-2000s financial crisis. Ferguson says the film is about "the systemic corruption of the United States by the financial services industry and the consequences of that systemic corruption". In five parts, the film explores how changes in the policy environment and banking practices helped create the financial crisis.
Document 14: Sicko: Sicko is a 2007 American documentary film made by filmmaker Michael Moore. The film investigates health care in the United States, focusing on its health insurance and the pharmaceutical industry. The movie compares the for-profit, non-universal U.S. system with the non-profit universal health care systems of Canada, the United Kingdom, France and Cuba.
Document 15: Dallas Buyers Club: Dallas Buyers Club is a 2013 American biographical drama film, co-written by Craig Borten and Melisa Wallack, and directed by Jean-Marc Vallée. The film tells the story of Ron Woodroof, an AIDS patient diagnosed in the mid 1980s when HIV/AIDS treatments were under-researched, while the disease was not understood and highly stigmatized. As part of the experimental AIDS treatment movement, he smuggled unapproved pharmaceutical drugs into Texas for treating his symptoms, and distributed them to fellow people with AIDS by establishing the "Dallas Buyers Club" while facing opposition from the Food and Drug Administration (FDA). Two fictional supporting characters, Dr. Eve Saks (Jennifer Garner), and Rayon (Jared Leto), were composite roles created from the writer's interviews with transgender AIDS patients, activists, and doctors.
ground_truth: 1886