Question: At most, how many people have died from plague where the House of Wisdom was held?

full_context: Document 1: Middle Ages: Religious beliefs in the Eastern Empire and Iran were in flux during the late sixth and early seventh centuries. Judaism was an active proselytising faith, and at least one Arab political leader converted to it. Christianity had active missions competing with the Persians' Zoroastrianism in seeking converts, especially among residents of the Arabian Peninsula. All these strands came together with the emergence of Islam in Arabia during the lifetime of Muhammad (d. 632). After his death, Islamic forces conquered much of the Eastern Empire and Persia, starting with Syria in 634–635 and reaching Egypt in 640–641, Persia between 637 and 642, North Africa in the later seventh century, and the Iberian Peninsula in 711. By 714, Islamic forces controlled much of the peninsula in a region they called Al-Andalus.The Islamic conquests reached their peak in the mid-eighth century. The defeat of Muslim forces at the Battle of Tours in 732 led to the reconquest of southern France by the Franks, but the main reason for the halt of Islamic growth in Europe was the overthrow of the Umayyad Caliphate and its replacement by the Abbasid Caliphate. The Abbasids moved their capital to Baghdad and were more concerned with the Middle East than Europe, losing control of sections of the Muslim lands. Umayyad descendants took over the Iberian Peninsula, the Aghlabids controlled North Africa, and the Tulunids became rulers of Egypt. By the middle of the 8th century, new trading patterns were emerging in the Mediterranean; trade between the Franks and the Arabs replaced the old Roman economy. Franks traded timber, furs, swords and slaves in return for silks and other fabrics, spices, and precious metals from the Arabs.
Document 2: Black Death: The Black Death is thought to have originated in the arid plains of Central Asia, where it then travelled along the Silk Road, reaching Crimea by 1343. From there, it was most likely carried by Oriental rat fleas living on the black rats that were regular passengers on merchant ships. Spreading throughout the Mediterranean and Europe, the Black Death is estimated to have killed 30–60% of Europe's total population. In total, the plague reduced the world population from an estimated 450 million down to 350–375 million in the 14th century. The world population as a whole did not recover to pre-plague levels until the 17th century. The plague recurred occasionally in Europe until the 19th century.
Document 3: Black Death: In 1466, perhaps 40,000 people died of the plague in Paris. During the 16th and 17th centuries, the plague was present in Paris around 30 per cent of the time. The Black Death ravaged Europe for three years before it continued on into Russia, where the disease was present somewhere in the country 25 times between 1350 to 1490. Plague epidemics ravaged London in 1563, 1593, 1603, 1625, 1636, and 1665, reducing its population by 10 to 30% during those years. Over 10% of Amsterdam's population died in 1623–25, and again in 1635–36, 1655, and 1664. Plague occurred in Venice 22 times between 1361 and 1528. The plague of 1576–77 killed 50,000 in Venice, almost a third of the population. Late outbreaks in central Europe included the Italian Plague of 1629–1631, which is associated with troop movements during the Thirty Years' War, and the Great Plague of Vienna in 1679. Over 60% of Norway's population died in 1348–50. The last plague outbreak ravaged Oslo in 1654.
Document 4: Translation: Translation of material into Arabic expanded after the creation of Arabic script in the 5th century, and gained great importance with the rise of Islam and Islamic empires. Arab translation initially focused primarily on politics, rendering Persian, Greek, even Chinese and Indic diplomatic materials into Arabic. It later focused on translating classical Greek and Persian works, as well as some Chinese and Indian texts, into Arabic for scholarly study at major Islamic learning centers, such as the Al-Karaouine (Fes, Morocco), Al-Azhar (Cairo, Egypt), and the Al-Nizamiyya of Baghdad. In terms of theory, Arabic translation drew heavily on earlier Near Eastern traditions as well as more contemporary Greek and Persian traditions.
Document 5: Black Death: The Black Death is thought to have originated in the arid plains of Central Asia, where it then travelled along the Silk Road, reaching Crimea by 1343. From there, it was most likely carried by Oriental rat fleas living on the black rats that were regular passengers on merchant ships. Spreading throughout the Mediterranean and Europe, the Black Death is estimated to have killed 30 -- 60% of Europe's total population. In total, the plague may have reduced the world population from an estimated 450 million down to 350 -- 375 million in the 14th century. The world population as a whole did not recover to pre-plague levels until the 17th century. The plague recurred occasionally in Europe until the 19th century.
Document 6: Black Death: The plague disease, caused by Yersinia pestis, is enzootic (commonly present) in populations of fleas carried by ground rodents, including marmots, in various areas including Central Asia, Kurdistan, Western Asia, Northern India and Uganda. Nestorian graves dating to 1338–39 near Lake Issyk Kul in Kyrgyzstan have inscriptions referring to plague and are thought by many epidemiologists to mark the outbreak of the epidemic, from which it could easily have spread to China and India. In October 2010, medical geneticists suggested that all three of the great waves of the plague originated in China. In China, the 13th century Mongol conquest caused a decline in farming and trading. However, economic recovery had been observed at the beginning of the 14th century. In the 1330s a large number of natural disasters and plagues led to widespread famine, starting in 1331, with a deadly plague arriving soon after. Epidemics that may have included plague killed an estimated 25 million Chinese and other Asians during the 15 years before it reached Constantinople in 1347.
Document 7: Madrasa: From around 750, during the Abbasid Caliphate, women “became renowned for their brains as well as their beauty”. In particular, many well known women of the time were trained from childhood in music, dancing and poetry. Mahbuba was one of these. Another feminine figure to be remembered for her achievements was Tawaddud, "a slave girl who was said to have been bought at great cost by Hārūn al-Rashīd because she had passed her examinations by the most eminent scholars in astronomy, medicine, law, philosophy, music, history, Arabic grammar, literature, theology and chess". Moreover, among the most prominent feminine figures was Shuhda who was known as "the Scholar" or "the Pride of Women" during the 12th century in Baghdad. Despite the recognition of women's aptitudes during the Abbasid dynasty, all these came to an end in Iraq with the sack of Baghdad in 1258.
Document 8: Abbasid Caliphate: Abbasid Caliphate ٱلْخِلافَةُ ٱلْعَبَّاسِيَّة 750 -- 1258 1261 -- 1517 (under the Mamluk Sultanate of Cairo) Black Standard Abbasid Caliphate at its greatest extent, c. 850. Capital Kufa (750 -- 762) Baghdad (762 -- 796, 809 -- 836, 892 -- 1258) Raqqa (796 -- 809) Samarra (836 -- 892) Cairo (1261 -- 1517) Languages Arabic (central administration); various regional languages Religion Sunni Islam Government Caliphate Caliph 750 -- 754 As - Saffah (first) 1242 -- 1258 Al - Musta'sim (last Caliph in Baghdad) 1508 -- 1517 al - Mutawakkil III (last Caliph in Cairo) History Established 750 Disestablished 1517 Currency Dinar (gold coin) Dirham (silver coin) Fals (copper coin) Preceded by Succeeded by Umayyad Caliphate Ottoman Empire Fatimid Caliphate Mamluk Sultanate (Cairo) Saffarid dynasty Ziyadid dynasty Aghlabids Mongol Empire
Document 9: Black Death: The Black Death was one of the most devastating pandemics in human history, resulting in the deaths of an estimated 75 to 200 million people in Eurasia and peaking in Europe from 1346 to 1353. The bacterium Yersinia pestis, resulting in several forms of plague, is believed to have been the cause. The plague created a series of religious, social, and economic upheavals, which had profound effects on the course of European history.
Document 10: Madrasa: At the beginning of the Caliphate or Islamic Empire, the reliance on courts initially confined sponsorship and scholarly activities to major centres. Within several centuries, the development of Muslim educational institutions such as the madrasah and masjid eventually introduced such activities to provincial towns and dispersed them across the Islamic legal schools and Sufi orders. In addition to religious subjects, they also taught the "rational sciences," as varied as mathematics, astronomy, astrology, geography, alchemy, philosophy, magic, and occultism, depending on the curriculum of the specific institution in question. The madaris, however, were not centres of advanced scientific study; scientific advances in Islam were usually carried out by scholars working under the patronage of royal courts. During this time,[when?] the Caliphate experienced a growth in literacy, having the highest literacy rate of the Middle Ages, comparable to classical Athens' literacy in antiquity but on a much larger scale. The emergence of the maktab and madrasa institutions played a fundamental role in the relatively high literacy rates of the medieval Islamic world.
Document 11: Middle Ages: The Islamic conquests reached their peak in the mid-8th century. The defeat of Muslim forces at the Battle of Poitiers in 732 led to the reconquest of southern France by the Franks, but the main reason for the halt of Islamic growth in Europe was the overthrow of the Umayyad dynasty and its replacement by the Abbasid dynasty. The Abbasids moved their capital to Baghdad and were more concerned with the Middle East than Europe, losing control of sections of the Muslim lands. Umayyad descendants took over the Iberian Peninsula, the Aghlabids controlled North Africa, and the Tulunids became rulers of Egypt. By the middle of the 8th century, new trading patterns were emerging in the Mediterranean; trade between the Franks and the Arabs replaced the old Roman patterns of trade. Franks traded timber, furs, swords and slaves in return for silks and other fabrics, spices, and precious metals from the Arabs.
Document 12: Muslim world: The Islamic Golden Age coincided with the Middle Ages in the Muslim world, starting with the rise of Islam and establishment of the first Islamic state in 622. The end of the age is variously given as 1258 with the Mongolian Sack of Baghdad, or 1492 with the completion of the Christian Reconquista of the Emirate of Granada in Al-Andalus, Iberian Peninsula. During the reign of the Abbasid caliph Harun ar-Rashid (786 to 809), the legendary House of Wisdom was inaugurated in Baghdad where scholars from various parts of the world sought to translate and gather all the known world's knowledge into Arabic. The Abbasids were influenced by the Quranic injunctions and hadiths, such as "the ink of a scholar is more holy than the blood of a martyr," that stressed the value of knowledge. The major Islamic capital cities of Baghdad, Cairo, and Córdoba became the main intellectual centers for science, philosophy, medicine, and education. During this period, the Muslim world was a collection of cultures; they drew together and advanced the knowledge gained from the ancient Greek, Roman, Persian, Chinese, Indian, Egyptian, and Phoenician civilizations.
Document 13: Black Death: In the first half of the 17th century, a plague claimed some 1.7 million victims in Italy, or about 14% of the population. In 1656, the plague killed about half of Naples' 300,000 inhabitants. More than 1.25 million deaths resulted from the extreme incidence of plague in 17th-century Spain. The plague of 1649 probably reduced the population of Seville by half. In 1709–13, a plague epidemic that followed the Great Northern War (1700–21, Sweden v. Russia and allies) killed about 100,000 in Sweden, and 300,000 in Prussia. The plague killed two-thirds of the inhabitants of Helsinki, and claimed a third of Stockholm's population. Europe's last major epidemic occurred in 1720 in Marseille.
Document 14: Black Death: The Black Death ravaged much of the Islamic world. Plague was present in at least one location in the Islamic world virtually every year between 1500 and 1850. Plague repeatedly struck the cities of North Africa. Algiers lost 30 to 50 thousand inhabitants to it in 1620–21, and again in 1654–57, 1665, 1691, and 1740–42. Plague remained a major event in Ottoman society until the second quarter of the 19th century. Between 1701 and 1750, thirty-seven larger and smaller epidemics were recorded in Constantinople, and an additional thirty-one between 1751 and 1800. Baghdad has suffered severely from visitations of the plague, and sometimes two-thirds of its population has been wiped out.
Document 15: Black Death: The plague struck various countries in the Middle East during the pandemic, leading to serious depopulation and permanent change in both economic and social structures. As it spread to western Europe, the disease entered the region from southern Russia also. By autumn 1347, the plague reached Alexandria in Egypt, probably through the port's trade with Constantinople, and ports on the Black Sea. During 1347, the disease travelled eastward to Gaza, and north along the eastern coast to cities in Lebanon, Syria and Palestine, including Ashkelon, Acre, Jerusalem, Sidon, Damascus, Homs, and Aleppo. In 1348–49, the disease reached Antioch. The city's residents fled to the north, most of them dying during the journey, but the infection had been spread to the people of Asia Minor.[citation needed]
ground_truth: two-thirds of its population
sub_queries: Where was the House of Wisdom held? Answer: Baghdad
How many people, at most, have died of plague in Baghdad ? Answer: two-thirds of its population