Question: Werner Gunter Jaffé Fellner was born in which metropolis and the largest city in the German state of Hesse and the fifth-largest city in Germany?

full_context: Document 1: Hesse: Hesse ( or ) or Hessia (German: "Hessen" ] , Hessian dialect: "Hesse" ] ) is a federal state ("Land") of the Federal Republic of Germany, with just over six million inhabitants. The state capital is Wiesbaden; the largest city is Frankfurt am Main. Until the unification of Germany, the territory of Hesse was occupied by the Grand Duchy of Hesse, the Duchy of Nassau, the free city of Frankfurt and the Electorate of Hesse, known also as Hesse-Cassel. Due to divisions after World War II, the modern federal state does not cover the entire cultural region of Hesse, which includes both the State of Hesse and the area known as Rhenish Hesse (Rheinhessen) in the neighbouring state of Rhineland-Palatinate.
Document 2: Guido Goldschmiedt: Goldschmiedt was born in Triest, Austria-Hungary. He started studying economics at the business school in Frankfurt am Main, but then started attending science lectures in other educational institutions. In 1869, he went back to Vienna, where part of his family lived, and studied chemistry at the University of Vienna. There he attended lectures of Josef Redtenbacher and Franz Cölestin Schneider – the most prominent chemists of the time in Vienna. In 1871, he moved to the University of Heidelberg, Germany. There he received his PhD for work with Robert Wilhelm Bunsen and his assistant Blum in the field of inorganic analytical chemistry of minerals. For a postdoctoral position, he joined the laboratory of Adolf von Baeyer at the University of Straßburg. Goldschmiedt worked in the field of organic chemistry for two years, but he also studied mineralogy and crystallography with Paul Heinrich von Groth. During that time, Emil Fischer and Franz S. Exner also worked with Baeyer in Straßburg. For Goldschmiedt, the time in Straßburg ended abruptly because he joined the group of Schneiders at the University of Vienna. After his habilitation in 1875, he was sent as official observer to the world fair in Philadelphia in 1876. After visiting California, he went back to Vienna and married in 1886. It took until 1890 for him to become assistant professor at University of Vienna, but only one year later he became full professor. In 1891, Goldschmiedt moved to the German Charles-Ferdinand University in Prague and worked there for 20 years. In the meantime, he received the Lieben Prize in 1892 and became a member of the Vorstand of Deutschen Chemischen Gesellschaft in 1900 and 1901. In 1911, Goldschmiedt succeeded Zdenko Hans Skraup at the University of Vienna and was mostly involved in administrative tasks, such as supervising the construction of the laboratory building and reorganization of the institute. Starting from 1914, his health deteriorated slowly but steadily, resulting in his eventual death on August 6, 1915.
Document 3: Germany: Germany ( ; German: "Deutschland" , ] ), officially the Federal Republic of Germany (German: "Bundesrepublik Deutschland" ,    ), is a federal parliamentary republic in central-western Europe. It includes 16 constituent states, covers an area of 357,021 km2 , and has a largely temperate seasonal climate. With about 82 million inhabitants, Germany is the most populous member state of the European Union. After the United States, it is the second most popular immigration destination in the world. Germany's capital and largest metropolis is Berlin, while its largest conurbation is the Ruhr, with its main centres of Dortmund and Essen. The country's other major cities are Hamburg, Munich, Cologne, Frankfurt, Stuttgart, Düsseldorf, Leipzig, Bremen, Dresden, Hannover and Nuremberg.
Document 4: Rudolf Christian Böttger: Böttger was born in Aschersleben, Germany in 1806. After attending the primary school there he joined the school of the Franksche Stiftung in Halle an der Saale at the age of eleven. In 1824, Böttger started to study theology, but in parallel also attended the science lectures at the University Halle. The lectures of Johann Salomo Christoph Schweigger had a strong influence on him. Böttger left the university in 1828 and worked as cleric and teacher at different locations. The contact with Schweigger never faded and in 1831 Böttger decided to leave the theology career. He was offered a job at the voluntary association for chemistry in Frankfurt in 1835. His first major work in Frankfurt was the improvement of the electrotyping method for the production of printing plates. Böttger received his PhD from the University of Jena in 1837 and was appointed as full professor in Frankfurt in 1842. Böttger married Christiane Harpke in 1841, and they had eight children. He and Christian Friedrich Schönbein, a German-Swiss chemist, discovered nitrocellulose independently in 1846. Both scientists collaborated to earn money with the invention, but they were not successful. The development of the safety match in 1848 and the synthesis of the first organocopper compound, the explosive copper(I) acetylide CuC in 1859 were examples for his chemistry research. Böttger stayed at the University of Frankfurt am Main for the rest of his life, although he was offered positions at other universities. He died of a liver illness in 1881.
Document 5: Werner Jaffé: Werner Gunter Jaffé Fellner (October 27, 1914 - May 3, 2009) was a chemist and university professor. Jaffé was born in Frankfurt. He received his doctoral degree at the University of Zurich under the supervision of the Nobel Prize winner Paul Karrer. After graduating, Jaffé arrived in Venezuela in 1940 and became a professor at the Central University of Venezuela. He started the teaching of Biochemistry at the Central University and founded the "Instituto Nacional de Nutrición". He was cofounder of the Venezuelan Association for the Advancement of Science. in 1946 he received a grant from the Rockefeller Foundation and, among several science prizes, he was awarded the "Premio Nacional de Ciencia , CONICIT" in 1978. During the fifty years that he taught at the college level, he also published over 200 academic publications and was named honorary professor at the Simón Bolívar University. He died in Caracas in 2009.
Document 6: Bonn: The Federal City of Bonn (] ) is a city on the banks of the Rhine in the German state of North Rhine-Westphalia, with a population of over 300,000. About 24 km south-southeast of Cologne, Bonn is in the southernmost part of the Rhine-Ruhr region, Germany's largest metropolitan area, with over 11 million inhabitants.
Document 7: Frankfurt: Frankfurt, officially Frankfurt am Main (Literally "Frankfurt on the Main", ] ), is a metropolis and the largest city in the German state of Hesse and the fifth-largest city in Germany, with a 2015 population of 732,688 within its administrative boundaries, and 2.3 million in its urban area. The city is at the centre of the larger Frankfurt Rhine-Main Metropolitan Region, which has a population of 5.5 million and is Germany's second-largest metropolitan region after Rhine-Ruhr. Since the enlargement of the European Union in 2013, the geographic centre of the EU is about 40 km to the east of Frankfurt's CBD, the Bankenviertel. Frankfurt is culturally and ethnically diverse, with around half of the population, and a majority of young people, having a migration background. A quarter of the population are foreign nationals, including many expatriates.
Document 8: Frankfurt: Frankfurt, officially Frankfurt am Main (Literally "Frankfurt on the Main", ] ), is a metropolis and the largest city in the German state of Hesse and the fifth-largest city in Germany, with a 2015 population of 732,688 within its administrative boundaries, and 2.3 million in its urban area. The city is at the centre of the larger Frankfurt Rhine-Main Metropolitan Region, which has a population of 5.5 million and is Germany's second-largest metropolitan region after Rhine-Ruhr. Since the enlargement of the European Union in 2013, the geographic centre of the EU is about 40 km to the east of Frankfurt's CBD, the Bankenviertel. Frankfurt is culturally and ethnically diverse, with around half of the population, and a majority of young people, having a migration background. A quarter of the population are foreign nationals, including many expatriates.
Document 9: Lotte Loewe: Lotte Loewe (November 7, 1900-unknown) was a German chemist known for her research in organic chemistry. Loewe received her doctorate in chemistry from the University of Breslau in 1937 and began her career there shortly thereafter, spending six years as a chemistry assistant from 1927 to 1933. She then moved to the University of Zurich for one year (1934) and the University of Istanbul for 21 years, from 1934 to 1955. Her last academic appointment was at the University of Basel, where she spent 6 years from 1955 to 1961. Loewe then became an industrial chemist in Basel, though she maintained a position as an assistant professor at the University of Freiberg. Throughout, her research concerned ascorbic acid reaction kinetics, uric acid, carotenoids, keto-enol tautomerism, and diazomethane reactions.
Document 10: M. Jaffar-ur-Rehman: He topped Quaid-i-Azam University by setting an all-time Computer Science Department record of a cumulative grade point average (CGPA) of 4.9 on a scale of 5.0. In result, he was awarded the Quaid-e-Azam Scholarship for higher studies abroad, which he used to receive his Master of Science (M.Sc) degree and his Ph.D. in computer science in the United States. He completed his M.Sc. in just one year at the University of Pennsylvania by securing a CGPA of 3.9 on a scale of 4.0. He taught in Australia for around three years during his Ph.D. He came back to Pakistan after fully completing his Ph.D., where he taught at Quaid-e-Azam University, Bahauddin Zakariya University, Lahore University of Management Sciences (LUMS), and then Mohammad Ali Jinnah University.
Document 11: Jean Fréchet: Professor Jean M.J. Fréchet (born August 19, 1944, Burgundy, France), American chemist, is a Professor Emeritus at the University of California, Berkeley. In addition, he is the head of Materials Synthesis, Materials Science Division,of the Lawrence Berkeley National Laboratory, Director of the Organic and Macromolecular Facility for the Molecular Foundry, Lawrence Berkeley National Laboratory, and Vice-President for research at King Abdullah University of Science and Technology. He has authored nearly 900 scientific papers and holds over 70 United States Patents. His research areas include organic synthesis and polymer chemistry applied to nanoscience and nanotechnology with emphasis on the design, fundamental understanding, synthesis, and applications of functional macromolecules. He was a good friend of influential American chemist Linus Pauling and consistently mentions him in his organic chemistry lectures. As of March 2011, he is 16th on the Hirsch index rating of all living chemists with an H-index of 105. He is an elected fellow of the American Association for the Advancement of Science, the American Chemical Society, and the American Academy of Arts and Sciences, and an elected member of the US National Academy of Sciences, the US National Academy of Engineering, and the Academy of Europe (Academia Europaea).
Document 12: Frankfurt Airport: Frankfurt Airport (IATA: FRA, ICAO: EDDF) (German: "Flughafen Frankfurt am Main" , also known as "Rhein-Main-Flughafen") is a major international airport located in Frankfurt, the fifth-largest city of Germany and one of the world's leading financial centres. It is operated by Fraport and serves as the main hub for Lufthansa including Lufthansa CityLine and Lufthansa Cargo as well as Condor and AeroLogic. The airport covers an area of 4942 acres of land and features two passenger terminals with a capacity of approximately 65 million passengers per year, four runways and extensive logistics and maintenance facilities.
Document 13: Juan Gualterio Roederer: Juan G. Roederer is a professor of physics emeritus at the University of Alaska Fairbanks (UAF). His research fields are space physics, psychoacoustics, science policy and information theory. He conducted pioneering research on solar cosmic rays, on the theory of earth’s radiation belts, neural networks for pitch processing, and currently on the foundations of information theory. He is also an accomplished organist.
Document 14: Paul Houston: Paul L. Houston is Professor of Chemistry and Biochemistry at The Georgia Institute of Technology. Most recently, he was Dean of the College of Sciences at Georgia Tech (from 2007-2013). He started his professorial career at Cornell University in 1975 following undergraduate study at Yale, doctoral work at MIT, and postdoctoral research at the University of California at Berkeley. He was formerly Chair of the Cornell Department of Chemistry and Chemical Biology (1997–2001), Senior Associate Dean of the College of Arts and Sciences (2002–2005), and the Peter J. W. Debye Professor of Chemistry. He was a member of the Cornell Center for Materials Research, the Kavli Institute at Cornell for Nanoscale Science, and the Graduate Field of Applied Physics. Dr. Houston has held visiting positions at the Max Planck Institute for Quantum Optics (1982), Columbia University (1986, 1987), the Institute for Molecular Science, Okazaki, Japan (1989), the University of California at Berkeley (2003), and the University of Rome La Sapienza (2001, 2006). He has been an Alfred P. Sloan Research Fellow (1979–81), a Camille and Henry Dreyfus Teacher Scholar (1980), and a John Simon Guggenheim Fellow (1986–87). He served as a Senior Editor of the Journal of Physical Chemistry (1991–97), as Chair of the American Physical Society Division of Laser Chemistry (1997–98), and as a member of the Science and Technology Steering Committee of Brookhaven National Laboratories (1998–2005). Houston has authored or co-authored over 160 publications in the field of physical chemistry and a textbook on chemical kinetics. In 2001 he shared with David W. Chandler the Herbert P. Broida Prize of the American Physical Society for work on product imaging in chemical dynamics. He was elected a fellow of the American Academy of Arts and Sciences in 2005.
Document 15: Düsseldorf: Düsseldorf (] , Low Franconian, Ripuarian: "Düsseldörp" [ˈdʏsl̩dœɐ̯p] ) is the capital city of the German state of North Rhine-Westphalia and the seventh most populous city in Germany. Düsseldorf is an international business and financial centre, renowned for its fashion and trade fairs. The city is headquarters to one Fortune Global 500 and two DAX companies. Messe Düsseldorf organises nearly one fifth of premier trade shows.
ground_truth: Frankfurt