Question: What human health problems has the substance used to extract gold and silver from their ores been directly linked to?

full_context: Document 1: Copper: The gates of the Temple of Jerusalem used Corinthian bronze made by depletion gilding. It was most prevalent in Alexandria, where alchemy is thought to have begun. In ancient India, copper was used in the holistic medical science Ayurveda for surgical instruments and other medical equipment. Ancient Egyptians (~2400 BC) used copper for sterilizing wounds and drinking water, and later on for headaches, burns, and itching. The Baghdad Battery, with copper cylinders soldered to lead, dates back to 248 BC to AD 226 and resembles a galvanic cell, leading people to believe this was the first battery; the claim has not been verified.
Document 2: Paper: Conventional bleaching of wood pulp using elemental chlorine produces and releases into the environment large amounts of chlorinated organic compounds, including chlorinated dioxins. Dioxins are recognized as a persistent environmental pollutant, regulated internationally by the Stockholm Convention on Persistent Organic Pollutants. Dioxins are highly toxic, and health effects on humans include reproductive, developmental, immune and hormonal problems. They are known to be carcinogenic. Over 90% of human exposure is through food, primarily meat, dairy, fish and shellfish, as dioxins accumulate in the food chain in the fatty tissue of animals.
Document 3: Zinc: Brass, which is an alloy of copper and zinc, has been used since at least the 10th century BC in Judea and by the 7th century BC in Ancient Greece. Zinc metal was not produced on a large scale until the 12th century in India and was unknown to Europe until the end of the 16th century. The mines of Rajasthan have given definite evidence of zinc production going back to the 6th century BC. To date, the oldest evidence of pure zinc comes from Zawar, in Rajasthan, as early as the 9th century AD when a distillation process was employed to make pure zinc. Alchemists burned zinc in air to form what they called "philosopher's wool" or "white snow".
Document 4: Alloy: Iron is usually found as iron ore on Earth, except for one deposit of native iron in Greenland, which was used by the Inuit people. Native copper, however, was found worldwide, along with silver, gold and platinum, which were also used to make tools, jewelry, and other objects since Neolithic times. Copper was the hardest of these metals, and the most widely distributed. It became one of the most important metals to the ancients. Eventually, humans learned to smelt metals such as copper and tin from ore, and, around 2500 BC, began alloying the two metals to form bronze, which is much harder than its ingredients. Tin was rare, however, being found mostly in Great Britain. In the Middle East, people began alloying copper with zinc to form brass. Ancient civilizations took into account the mixture and the various properties it produced, such as hardness, toughness and melting point, under various conditions of temperature and work hardening, developing much of the information contained in modern alloy phase diagrams. Arrowheads from the Chinese Qin dynasty (around 200 BC) were often constructed with a hard bronze-head, but a softer bronze-tang, combining the alloys to prevent both dulling and breaking during use.
Document 5: Alloy: Mercury has been smelted from cinnabar for thousands of years. Mercury dissolves many metals, such as gold, silver, and tin, to form amalgams (an alloy in a soft paste, or liquid form at ambient temperature). Amalgams have been used since 200 BC in China for plating objects with precious metals, called gilding, such as armor and mirrors. The ancient Romans often used mercury-tin amalgams for gilding their armor. The amalgam was applied as a paste and then heated until the mercury vaporized, leaving the gold, silver, or tin behind. Mercury was often used in mining, to extract precious metals like gold and silver from their ores.
Document 6: Alvaro Alonso Barba: In 1609, he invented the "pan amalgamation" process (in Spanish the "cazo" or "fondo" process) for extracting silver from ore by mixing it with salt and mercury and heating it in shallow copper vessels. In 1640 he published in Madrid a book entitled "Arte de los Metales", the earliest work on South American ores and minerals. It includes information on mineral localities in Bolivia. The book has been republished in Spanish, French and English.
Document 7: 1971 Iraq poison grain disaster: The 1971 Iraq poison grain disaster was a mass methylmercury poisoning incident that began in late 1971. Grain treated with a methylmercury fungicide and never intended for human consumption was imported into Iraq as seed grain from Mexico and the United States. Due to a number of factors, including foreign-language labelling and late distribution within the growing cycle, this toxic grain was consumed as food by Iraqi residents in rural areas. People suffered from paresthesia (numbness of skin), ataxia (lack of coordination of muscle movements) and vision loss, symptoms similar to those seen when Minamata disease affected Japan. The recorded death toll was 459 people, but figures at least ten times greater have been suggested.  The 1971 poisoning was the largest mercury poisoning disaster when it occurred, with cases peaking in January and February 1972 and stopping by the end of March.
Document 8: Liquid metal: Liquid metal consists of alloys with very low melting points which form a eutectic that is liquid at room temperature. The standard metal used to be mercury, but gallium - based alloys, which are lower both in their vapor pressure at room temperature and toxicity, are being used as a replacement in various applications.
Document 9: Alloy: Many ancient civilizations alloyed metals for purely aesthetic purposes. In ancient Egypt and Mycenae, gold was often alloyed with copper to produce red-gold, or iron to produce a bright burgundy-gold. Gold was often found alloyed with silver or other metals to produce various types of colored gold. These metals were also used to strengthen each other, for more practical purposes. Copper was often added to silver to make sterling silver, increasing its strength for use in dishes, silverware, and other practical items. Quite often, precious metals were alloyed with less valuable substances as a means to deceive buyers. Around 250 BC, Archimedes was commissioned by the king to find a way to check the purity of the gold in a crown, leading to the famous bath-house shouting of "Eureka!" upon the discovery of Archimedes' principle.
Document 10: Copper: The uses of copper in art were not limited to currency: it was used by Renaissance sculptors, in photographic technology known as the daguerreotype, and the Statue of Liberty. Copper plating and copper sheathing for ships' hulls was widespread; the ships of Christopher Columbus were among the earliest to have this feature. The Norddeutsche Affinerie in Hamburg was the first modern electroplating plant starting its production in 1876. The German scientist Gottfried Osann invented powder metallurgy in 1830 while determining the metal's atomic mass; around then it was discovered that the amount and type of alloying element (e.g., tin) to copper would affect bell tones. Flash smelting was developed by Outokumpu in Finland and first applied at Harjavalta in 1949; the energy-efficient process accounts for 50% of the world's primary copper production.
Document 11: Nutrition: At the time of this entry, we were not able to identify any specific nutrition literacy studies in the U.S. at a national level. However, the findings of the 2003 National Assessment of Adult Literacy (NAAL) provide a basis upon which to frame the nutrition literacy problem in the U.S. NAAL introduced the first ever measure of "the degree to which individuals have the capacity to obtain, process and understand basic health information and services needed to make appropriate health decisions" – an objective of Healthy People 2010 and of which nutrition literacy might be considered an important subset. On a scale of below basic, basic, intermediate and proficient, NAAL found 13 percent of adult Americans have proficient health literacy, 44% have intermediate literacy, 29 percent have basic literacy and 14 percent have below basic health literacy. The study found that health literacy increases with education and people living below the level of poverty have lower health literacy than those above it.
Document 12: Mercury in fish: In the United States, the EPA serves as an advisory organ to set the levels of mercury that are non-fatal in humans. Symptoms of exposure to high levels of methyl mercury include disturbed vision, hearing, and speech, lack of coordination, and muscle weakness. Medical studies have examined the correlation of fish consumption and health issues. American studies have presented evidence of fish consumption and its effects on child development. Longitudinal studies agree that human activities are what release and accumulate mercury in marine life. Addressing the issues of fish consumption forces health officials to recognize the sources of mercury in the human body. Specific Native American tribes are vulnerable to a high exposure of mercury. Studies have determined that these native peoples in the United States suffer more from mercury poisoning and illness than any other cohort group in the country. This is due to the fact that fish is a main source of protein. Exposure risk was assessed through a medical study, thus raising judicial issues of whether the public health of these groups is a priority in the United States.
Document 13: Nutrition: Another study examining the health and nutrition literacy status of residents of the lower Mississippi Delta found that 52 percent of participants had a high likelihood of limited literacy skills. While a precise comparison between the NAAL and Delta studies is difficult, primarily because of methodological differences, Zoellner et al. suggest that health literacy rates in the Mississippi Delta region are different from the U.S. general population and that they help establish the scope of the problem of health literacy among adults in the Delta region. For example, only 12 percent of study participants identified the My Pyramid graphic two years after it had been launched by the USDA. The study also found significant relationships between nutrition literacy and income level and nutrition literacy and educational attainment further delineating priorities for the region.
Document 14: Noise pollution: The Environmental Protection Agency retains authority to investigate and study noise and its effect, disseminate information to the public regarding noise pollution and its adverse health effects, respond to inquiries on matters related to noise, and evaluate the effectiveness of existing regulations for protecting the public health and welfare, pursuant to the Noise Control Act of 1972 and the Quiet Communities Act of 1978.
Document 15: Nutrition: Research in the field of nutrition has greatly contributed in finding out the essential facts about how environmental depletion can lead to crucial nutrition-related health problems like contamination, spread of contagious diseases, malnutrition, etc. Moreover, environmental contamination due to discharge of agricultural as well as industrial chemicals like organocholrines, heavy metal, and radionucleotides may adversely affect the human and the ecosystem as a whole. As far as safety of the human health is concerned, then these environmental contaminants can reduce people's nutritional status and health. This could directly or indirectly cause drastic changes in their diet habits. Hence, food-based remedial as well as preventive strategies are essential to address global issues like hunger and malnutrition and to enable the susceptible people to adapt themselves to all these environmental as well as socio-economic alterations.
ground_truth: disturbed vision, hearing, and speech, lack of coordination, and muscle weakness
sub_queries: Gold and silver were extracted from their ores by using? Answer: Mercury
Mercury has been directly linked to which of the following health problems in humans Answer: disturbed vision, hearing, and speech, lack of coordination, and muscle weakness