guan-wang/ReDis-QA huggingface dataset:
Question: All are features of Abetalipoproteinemia, EXCEPT:
A. Plasma levels of cholesterol and triglyceride are extremely low
B. Manifest in early childhood with diarrhea
C. Progressive pigmented retinopathy seen
D. Neurological manifestation as ataxia in first decade
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Abetalipoproteinemia
Question: Abetalipoproteinemia is due to deficiency of -
A. Lecithin Cholesterol Acyl Transferase
B. ATP Binding Cassette Transporter-1
C. Mitochondrial Triglyceride Transfer Protein
D. ApoCII
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Abetalipoproteinemia
Question: Small intestinal biopsy is diagnostic in :a) Whipple's diseaseb) Abetalipoproteinemiac) Celiac diseased) Agammaglobulinemia
A. acd
B. bcd
C. abd
D. ab
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Abetalipoproteinemia, Agammaglobulinemia
Question: Intermittent dysphagia is caused by -a) Strictureb) Reflux esophagitisc) Achalasia cardiad) Pharyngeal diverticululame) Diffuse esophageal spasm
A. ab
B. bc
C. de
D. bd
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Achalasia
Question: Following are radiological evidence of Achalasia cardia except not related -radiology
A. Smooth narrowing of esophagus
B. Dilated touous esophagus
C. Absence of air in the fundus
D. Exaggerated peristalsis
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Achalasia
Question: Which drug is used for Achalasia cardia-
A. Nifedipine
B. Propranolal
C. Atenolol
D. Bethnecol
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Achalasia
Question: Achalasia is associated with increased risk of ...... malignancy:
A. Squamous cell carcinoma esophagus
B. Adenocarcinoma esophagus
C. Bronchogenic carcinoma
D. Bronchial adenoma
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Achalasia
Question: Which investigation is not required in diagnosis of Achalasia?
A. Esophageal manometry
B. Barium swallow
C. Anti-neuronal antibodies
D. Enterocylsis
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Achalasia
Question: About Achalasia Cardia: 1. Dysphagia is a presenting symptom 2. The cause is the absence of Auerbach's plexus 3. Esophagectomy is the treatment 4. Motility improving agents are used in treatment 5. Barium swallow shows irregular filling defects in lower esophagus
A. 1,2,3 False & 4,5 True
B. 1,2,4 True & 3,5 False
C. 2,3,4 True &1,5 False
D. 1,3,5 True & 2,4 False
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Achalasia
Question: Feature of Achalasia cardia (cardiospasm) include all of the following except-
A. Increasing dificulty in swallowing more for liquids than for soilds
B. Regurgitant vomiting
C. Dilated & turtuous esophagus
D. Filling defect on barium study
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Achalasia
Question: Barret's esophagus can lead to -a) Strictureb) Reflux esophagitisc) Peptic ulcerd) Achalasia
A. ac
B. bc
C. ad
D. b
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Achalasia
Question: Odynophagia occurs ina) Achalasiab) Herpes esophagitisc) Monilial esophagitisd) Barret's oesophagus
A. a
B. c
C. ac
D. bc
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Achalasia
Question: Achalasia cardia presents with all EXCEPT:
A. Increased lower esophalgus sphincter tone
B. Normal peristalsis
C. Dilatation proximally
D. Malignancy
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Achalasia
Question: Intermittent dysphagia is caused by -a) Strictureb) Reflux esophagitisc) Achalasia cardiad) Pharyngeal diverticulme) Diffuse esophageal spasm
A. ab
B. bc
C. cd
D. de
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Achalasia
Question: Radiologic feature suggestive of Achalasia cardia is?
A. Absence of gastric air bubble
B. Air fluid level in mediastinum
C. Sigmoid ecophagus
D. All of the above
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Achalasia
Question: Achalasia cardia due to:
A. Degeneration of myenteric plexus due to toxin
B. Degeneration and absence of ganglion cells in auerbach' Plexus
C. Excess of Ganglion cells in auerbach Plexus
D. Degeneration of meissner's Plexus
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Achalasia
Question: In which of the following condition does odynohagia occur? 1. Achalasia 2. Herpes esophagitis 3. Monilial esophagitis 4. Barrett's esophagus
A. 1 & 2
B. 2 & 3
C. 1,2 & 3
D. 1,2,3 & 4
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Achalasia
Question: Following are radiological evidence of Achalasia cardia Except
A. Beak like appearance
B. Dilated touous esophagus
C. Presence of air-fluid level
D. Exaggerated peristalsis
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Achalasia
Question: Which of the following disease causes Achalasia
A. Kala azar
B. Chaga's disease
C. KFD
D. Schistosomiasis
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Achalasia
Question: In which of the following conditions, uniform dilation of esophagus is seen -a)  Sclerodermab)  Achalasia cardiac) Dermatomyositisd) Trypanosoma cruzi infection
A. c
B. bd
C. ab
D. ac
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Achalasia, Dermatomyositis, Scleroderma
Question: Radiologic feature suggestive of Achalasia cardia is-
A. Absence of gastric air bubble
B. Air fluid level in mediastinum
C. Sigmoid ecophagus
D. All of the above
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Achalasia
Question: Intermittent dysphagia is caused by? 1. Stricture 2. Reflux esophagitis 3. Achalasia cardia 4. Pharyngeal diveiculum 5. Diffuse esophageal spasm
A. 1,2 & 3
B. 2,3 & 4
C. 4 & 5
D. 3,4 & 5
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Achalasia
Question: Gold standard Investigation for Achalasia cardia is :
A. Esophageal manometry
B. Barium swallow
C. Endoscopy
D. Endoscopic ultrasound
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Achalasia
Question: Achalasia cardia
A. Absence of nerves
B. Absence of muscles
C. Hyperophy of nerves
D. Hyperophy of muscles
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Achalasia
Question: Mode of inheritance forAchondroplasia is -
A. Autosomal dominant
B. Autosomal recessive
C. X-linked dominant
D. X- linked recessive
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Achondroplasia
Question: The features of Achondroplasia inlcude all,except -a) Defective headb) Mental retardationc)  Autosomal recessived) Familial
A. bc
B. c
C. ac
D. ad
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Achondroplasia
Question: Most common inheritance of Achondroplasia is
A. Sporadic
B. Autosomal dominant
C. Autosomal recessive
D. X-linked recessive
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Achondroplasia
Question: Achondroplasia shows which of the following type of inheritance
A. Autosomal Dominant
B. Autosomal Recessive
C. X-Linked Dominant
D. X-Linked Recessive
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Achondroplasia
Question: All of the following are features of Achondroplasia except:
A. Bullet shaped veebra
B. Trident hand/starfish hand
C. Wimberger ring sign
D. Champagne glass pelvis
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Achondroplasia
Question: Microcephaly is seen in
Beckwith hypoglycaemic syndrome
Fanconi syndrome
Down syndrome
Achondroplasia
A. I and iv
B. I and ii
C. ii and iii
D. ii and iv
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Achondroplasia
Question: True statement regarding Achondroplasia is :
A. AR inheritance
B. Shortened spine
C. Increased risk of pathological fracture
D. Diagnosed at birth by X-ray
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Achondroplasia
Question: If both husband and wife are suffering with Achondroplasia, what are their chances of having a normal child?
A. 0%
B. 25%
C. 50%
D. 100%
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Achondroplasia
Question: All are true about Achondroplasia except
A. Antosomal dominant
B. Acral osteolysis
C. Trident hand
D. Champaigne glass pelvis
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Achondroplasia
Question: Not a feature of Achondroplasia
A. Tombstone iliac bone
B. Champagne glass pelvis
C. Acromelic dwarfism
D. Bullet shaped veebra
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Achondroplasia
Question: Achondroplasia shows which of the following type of inheritance?
A. Autosomal dominant
B. Autosomal recessive
C. X linked dominant
D. X linked recessive
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Achondroplasia
Question: The earliest Cranial nerve involved in Acoustic Neuroma is:
A. V
B. VI
C. VII
D. X
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Acoustic Neuroma
Question: Acromegaly is due to excess of:
A. Somatomedin
B. Growth hormone
C. Somatostation
D. Insulin
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Acromegaly
Question: Deficiency of growth hormone leads to –a) Delayed fusion of epiphysisb) Proportionate dwarfismc) Acromegaly d)  Mental retardation
A. ac
B. a
C. ab
D. bc
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Acromegaly
Question: Acromegaly is associated with all of the following EXCEPT:
A. Nasal sinus enlargement
B. Increased heel pad thickness
C. Diabetes mellitus
D. Muscle hyperophy
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Acromegaly
Question: Angioid streaks is seen in -a) Pseudoxanthoma Elasticumb) Acromegalyc) Paget's diseased) All of above
A. a
B. ac
C. ad
D. b
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Acromegaly, Pseudoxanthoma Elasticum
Question: In Acromegaly All of the following are seen EXCEPT
A. Visceromegaly
B. Decreased sweating
C. Hypertension
D. Soft tissue and bone enlargement
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Acromegaly
Question: Confirmatory investigation for Acromegaly is:
A. Insulin induced GH suppression
B. Glucose induced GH suppression
C. Random GH assay
D. IGF - I level
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Acromegaly
Question: Acromegaly is a disorder of:
A. Excess growth hormone secretion during adulthood
B. Excess thyroxine secretion
C. Excess ACTH secretion
D. Excess FSH secretion
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Acromegaly
Question: Acromegaly results due to excessive release of:
A. Thyroxine
B. Growth hormone
C. Insulin
D. Glucagon
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Acromegaly
Question: Acromegaly is associated with
A. Class. I malocclusion
B. Class. I cross bite
C. Class. II malocclusion
D. Class. III malocclusion
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Acromegaly
Question: Drug used in Acute Intermittent Porphyria is
A. Opioids
B. Phenobarbitone
C. Primidone
D. Blood tranfusion
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Acute Intermittent Porphyria
Question: All of the following genetic syndromes are associated with Acute Myeloid Leukemia, except:
A. Down's Syndrome
B. Klinefelter's Syndrome
C. Patau Syndrome
D. Turner's Syndrome
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Acute Myeloid Leukemia
Question: A child with Acute Myeloid Leukemia presents with hyperleukocytosis. Treatment includes all of the following except ?
A. IV fluid
B. Allopurinol
C. Alkalinization
D. Immediately sta induction chemotherapy
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Acute Myeloid Leukemia
Question: Which of the following is a poor prognostic factor in Acute Myeloid Leukemia (AML)
A. Monosomy
B. Deletion of X or Y chromosome
C. t (8; 21) translocation
D. Nucleophosphin mutation
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Acute Myeloid Leukemia
Question: Non-specific esterase is positive in all the categories of Acute Myeloid Leukemia, EXCEPT:
A. M3
B. M4
C. M5
D. M6
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Acute Myeloid Leukemia
Question: The cause of the severe hemorrhage in Acute Promyelocytic Leukemia is?
A. Disseminated intravascular coagulation
B. Immune complex deposits on blood vessels
C. Thrombocytopenia
D. Thrombocytosis
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Acute Promyelocytic Leukemia
Question: A 26 year old man is critically ill, with multisystem organ failure, and he has not been able to give a clear history of respiratory distress. You suspect Acute Respiratory Distress Syndrome (ARDS). 1. The lung injury may be direct, as occurs in sepsis, or indirect, as occurs in Toxic inhalation 2. The aerial (a) PO2 (in mmHg)/FIO2 (inspiratory O2 fraction) > 200 mmHg is characteristic of ARDS 3. Ventilator-induced injury will be more with low tidal volume ventilation in ARDS 4. Moality was significantly lower in the high tidal volume ventilation, compared to the conventional tidal volume ventilated patients 5. High-dose glucocoicoids are useful in the care of ARDS patients
A. 1,2,5-True & 3,4-False
B. All True
C. All False
D. 3,4-True & 1,2,5-False
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Acute Respiratory Distress Syndrome
Question: Diffuse specific lesions on intestinal biopsy are seen in -a) Celiac sprueb) Whipples diseasec) Agammaglobulinemia d) Abetalipoproteinemal
A. abc
B. bcd
C. ac
D. bd
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Agammaglobulinemia
Question: Agammaglobulinemia can present with?
A. Rhinitis
B. Bronchiectasis
C. Giardia infections
D. All above
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Agammaglobulinemia
Question: Diagnosis of X linked Agammaglobulinemia should be suspected if:
A. Female sex
B. Absent tonsils and no palpable lymph nodes on physical examination
C. High isohemagglutinins titers
D. Low CD3
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Agammaglobulinemia
Question: Alkaptonuria an inherited metabolic disorder is due to the deficiency of
A. Homogentisate oxidase
B. Cystathionase
C. Pheylalanine hydroxylase
D. Tyrosine transaminase
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Alkaptonuria
Question: Alkaptonuria is caused by defect in which of the following enzymes?
A. Enolase
B. Homogentisate oxidase
C. Pyruvate carboxylase
D. None of the above
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Alkaptonuria
Question: Enzyme-deficient in Alkaptonuria
A. Phenylalanine hydroxylase
B. Cystathionine synthase
C. Homogentisic acid oxidase
D. Tyrosinase
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Alkaptonuria
Question: The earliest manifestation of Alkaptonuria is -
A. Ankylosis of lumbodorsal spine
B. Ochronotic arthritis
C. Prostatic calculi
D. Pigmentation of tympanic membrane
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Alkaptonuria
Question: Enzyme deficient in Alkaptonuria?
A. Phenylalanine hydroxylase
B. Cystathionine synthase
C. Homogentisic acid oxidase
D. Tyrosinase
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Alkaptonuria
Question: Which of the following is used to treat Alkaptonuria?
A. Vitamin A
B. Vitamin C
C. Vitamin D
D. Vitamin K
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Alkaptonuria
Question: Which substance gets accumulated in abnormal amounts in Alkaptonuria
A. Acetoacetate
B. Oxalate
C. Homogentisate
D. Phenylacetic acid
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Alkaptonuria
Question: Which is false about Alkaptonuria?
A. Genitourinary system not involved
B. Hemogentistic oxidase deficiency
C. Black urine
D. Calcification in veebral bodies
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Alkaptonuria
Question: Treatment of Alkaptonuria:
A. Vitamin A
B. Vitamin C
C. Vitamin D
D. Vitamin K
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Alkaptonuria
Question: Enzyme deficiency in Alkaptonuria is
A. Tyrosine hydroxylase
B. Homogentisate acid oxidase
C. Phenyl alanine hydroxylase
D. Cystathione synthase
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Alkaptonuria
Question: In Alkaptonuria deficiency is:
A. Phosphofructo kinase
B. HMG CoA reductase
C. Homogentisate oxidase
D. Xanthine oxidase
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Alkaptonuria
Question: Alkaptonuria is a metabolic disease caused by a defect in or lack of homogentisic acid oxidase which lead to
A. Absent patella
B. Blue sclera
C. Darkly pigmented sclera cornea & ear
D. Absent radii
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Alkaptonuria
Question: Calcification of intervertebral disc is seen in – a) Goutb) Rheumatoid c) Alkaptonuriad) Psoriasis
A. ac
B. bc
C. ad
D. b
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Alkaptonuria
Question: Alkaptonuria is due to deficiency of
A. Alkaptonase
B. Tyrosinase
C. Phenylalanine hydroxylase
D. Homogentisic acid oxidase
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Alkaptonuria
Question: All of the following are used in Alopecia Areata except
A. Tacrolimus
B. Acitretin
C. Steroids
D. Phototherapy
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Alopecia Areata
Question: Which one of the following is NOT true of Ameloblastoma -
A. Most common odontogenic tumour
B. Generally benign
C. Common in 3rd to 5th decade
D. Arises from mesenchymal tissue
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Ameloblastoma
Question: True about Ameloblastoma: (PGI Dec 2006)
A. Cystic lesion
B. Rapidly growing
C. Malignant disease
D. MC site is Tibia
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Ameloblastoma
Question: Ameloblastoma most frequently occurs in
A. Mandibular molar region
B. Maxillary molar region
C. Mandibular premolar region
D. Maxillary premolar region
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Ameloblastoma
Question: True about Ameloblastoma -a) Cystic lesionb) Rapidly growingc) Malignant diseased) MC site is Tibiae) Presented in children
A. ae
B. b
C. ab
D. ad
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Ameloblastoma
Question: Congo red staining of abdominal fat has confirmed a diagnosis of Amyloidosis in a 28-year-old man. Which is the most common cause of death in primary AL Amylodosis?
A. Respiratory failure
B. Cardiac failure
C. Renal failure
D. Septicemia
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Amyloidosis
Question: Amyloidosis of hea presents with -
A. Arrhythmia
B. AV block
C. |Ed mass/voltage
D. AS
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Amyloidosis
Question: Which type of Amyloidosis is caused by mutation of the transthyretin protein ?-
A. Familial Mediterranean fever
B. Familial amyloidotic polyneuropathy
C. Dialysis associated amyloidosis
D. Prion protein associated amyloidosis
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Amyloidosis
Question: Amyloidosis is most commonly seen in ?
A. Maturity onset DM
B. Type I DM
C. Type H DM
D. HTN
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Amyloidosis
Question: Amyloidosis is commonly associated with:
A. Chronic osteomyelitis
B. Periostitis
C. Acute osteomyelitis
D. Multiple myeloma
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Amyloidosis
Question: Amyloidosis causes which type of cardiomyopathy?
A. Constrictive
B. Restrictive
C. Hypertrophic
D. Any of the above
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Amyloidosis
Question: Polyneuropathy is seen in -a) Vitamin deficiencyb) Osteoporosisc) DMd) Myxoedemae) Amyloidosis
A. bce
B. acde
C. abcd
D. abde
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Amyloidosis
Question: Amyloidosis is seen in which type of diabetes mellitus?
A. Maturity onset DM
B. Type I DM
C. Type II DM
D. all of the above
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Amyloidosis
Question: Small intestinal biopsy is specific for-a)  Tropical sprueb)  Celiac spruec)  Whipple's diseased)  Amyloidosis
A. cd
B. bc
C. bd
D. ac
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Amyloidosis
Question: Amyloidosis mostly affects
A. Liver
B. Tounge
C. Colon
D. Hea
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Amyloidosis
Question: Confirmatory test for the diagnosis ofAmyloidosis is?
A. Diagnostic peritoneal lavage
B. Tongue biopsy
C. Rectal biopsy
D. Whole body CT scan
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Amyloidosis
Question: Amyloidosis shown in Cardiac muscle is mainly due to …….. fibril
A. AL
B. AA
C. AANF
D. ATTR
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Amyloidosis
Question: Major fibril protein in Primary Amyloidosis is ?
A. AL
B. AA
C. Transthyretin
D. Procalciton
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Amyloidosis
Question: Major fibril protein in Primary Amyloidosis is -
A. AL
B. AA
C. Transthyretin
D. Procalcitonin
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Amyloidosis
Question: Confirmatory test for the diagnosis of Amyloidosis-
A. Diagnostic peritoneal lavage
B. Tongue biopsy
C. Rectal biopsy
D. Whole body CT scan
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Amyloidosis
Question: Confirmatory test for the diagnosis of Amyloidosis is:
A. Diagnostic peritoneal lavage
B. Tongue biopsy
C. Rectal biopsy
D. Whole body CT scan
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Amyloidosis
Question: Amyloidosis of heart presents with -a) Arrhythmiab) AV blockc) ↑ed mass/voltage d) Hypertrophic cardiomyopathy
A. ab
B. abc
C. acd
D. bcd
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Amyloidosis
Question: Amyloidosis is most commonly seen in-
A. Maturity onset DM
B. Type I DM
C. Type II DM
D. HTN
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Amyloidosis
Question: Which type ofAmyloidosis is caused by mutation of the transthyretin protein ?
A. Familial Mediterranean fever
B. Familial amyloidotic polyneuropathy
C. Dialysis associated amyloidosis
D. Prion protein associated amyloidosis
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Amyloidosis
Question: Amyloidosis is most commonly seen in
A. Maturity onset DM
B. Type1DM
C. Type2DM
D. Equally seen with all forms of DM
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Amyloidosis
Question: Amyloidosis is?
A. RNA misfolding
B. DNA repair defect
C. Mitochondrial defect
D. Misfolding of protein
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Amyloidosis
Question: Paraneoplastic syndrome not seen in renal cell cancer is?a)  Acanthosis nigricansb) Amyloidosisc)  Polycythemiad)  SLE
A. b
B. c
C. ad
D. ab
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Amyloidosis
Question: Bone marrow in Amyloid Lightchain Amyloidosis shows which of the following features?
A. Bone marrow plasmacytosis
B. Granulomatous reaction
C. Fibrosis
D. Giant cell formation
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Amyloidosis
Question: Amyloidosis deposition most commonly occurs in:
A. Renal vessels
B. Knee joints
C. Skin
D. Cornea
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Amyloidosis
Question: Amyloidosis most commonly affects -
A. Liver
B. Tongue
C. Colon
D. Hea
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Amyloidosis
Question: Which type of Amyloidosis is caused by the mutation of a transthyretin protein?
A. Dialysis associated amyloidosis
B. Familial Mediterranean fever
C. Familial amyloidotic polyneuropathy
D. Prion protein associated amyloidosis
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Amyloidosis
Question: Egg shell calcifications can be seen in Sarcoidosis Silicosis Aspergillosis Pulmonary aery hypeension Amyloidosis scleroderma
A. 1,2,3,4
B. 1,2,4,5
C. 1,2,3,6
D. 1,2,5,6
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Amyloidosis, Aspergillosis
Question: Amyloidosis most commonly affects
A. Liver
B. Tongue
C. Colon
D. Hea
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Amyloidosis
Question: Amyloidosis is found in the following except ?
A. Multiple myeloma
B. Hypernephroma
C. Thymoma
D. Lymphoma
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Amyloidosis
Question: Protein implicated in Familial Amyloidosis is
A. Serum amyloid A
B. b2-microglobulin
C. Amyloid b peptide
D. Transthyretin
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Amyloidosis
Question: Amyloidosis is associated with which thyroid carcinoma?
A. Papillary
B. Follicular
C. Anaplastic
D. Medullary
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Amyloidosis
Question: Amyloidosis of kidney may be seen in the following except -
A. Enteric fever
B. Ulcerative colitis
C. Suppurative lung disease
D. Hansen's disease
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Amyloidosis
Question: Confirmatory test for the diagnosis of Amyloidosis is :
A. Diagnostic peritoneal lavage
B. Tongue biopsy
C. Rectal biopsy
D. Whole body CT scan
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Amyloidosis
Question: Amyloidosis of kidney may be seen in the following except-
A. Enteric fever
B. Ulcerative colitis
C. Suppurative lung disease
D. Hansen's disease
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Amyloidosis
Question: Amyloidosis deposition most commonly occurs in
A. Renal vessels
B. Knee joints
C. Skin
D. Cornea
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Amyloidosis
Question: Amyloidosis is associated with -
A. 21P
B. 22P
C. Y chromosome
D. 17 Q
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Amyloidosis
Question: Amyloidosis is most commonly seen in DM -
A. Maturity onset DM
B. Type I DM
C. Type II DM
D. Hypertension
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Amyloidosis
Question: Major fibril protein in Primary Amyloidosis is?
A. AL
B. AA
C. Transthyretin
D. Procalcitonin
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Amyloidosis
Question: Which of the following tests is abnormal in patients with ALS (Amyotrophic Lateral Sclerosis)?
A. V.E.P
B. MRI whole spine
C. CT whole Spine
D. Electromyography
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Amyotrophic Lateral Sclerosis
Question: A multigravida came for routine antenatal check up. She had a history of medical termination of pregnancy due to fetus with anencephaly. Anencephaly is best diagnosed in the present pregnancy by using:
A. Maternal Alpha fetoprotein
B. Amniotic fluid beta hCG
C. USG
D. X-ray
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Anencephaly
Question: The following are causes of face presentation in a foetus? 1. Anencephaly 2. Multiparity 3. Hydraminos 4. Contracted Pelvis 5. Placenta prae
A. 1, 2, 3 - False & 4, 5 - True
B. 2, 3, 4 - True & 1, 5 - False
C. 2, 3, 4 - False & 1, 5 - True
D. 1, 2, 4 - True & 3, 5 - False
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Anencephaly
Question: Anencephaly is earliest diagnosed at :
A. 6 weeks
B. 10 weeks
C. 14 weeks
D. 18 weeks
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Anencephaly
Question: Anencephaly can be diagnosed by ultrasound at:
A. 14-18 week of gestation
B. 20-24 week of gestation
C. 24-37 weeks of gestation
D. 10-12 week of gestation
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Anencephaly
Question: Which favor face presentation:a) Anencephalyb) Contracted pelvisc) Placenta praevia d) Thyroid swellinge) Bicornuate uterus
A. abd
B. bcd
C. abc
D. ab
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Anencephaly
Question: Anencephaly is best diagnosed using :
A. Maternal serum alpha-fetoprotein
B. Amniotic fluid alpha-fetoprotein
C. USG
D. X-ray
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Anencephaly
Question: Anencephaly is best diagnosed using:
A. Maternal serum alpha feto protein
B. Amniotic fluid alpha feto protein
C. USG
D. X-ray
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Anencephaly
Question: Anencephaly is associated with the following factor :
A. Hydramnios
B. Postmaturity
C. Prematurity
D. All of these
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Anencephaly
Question: Anencephaly can be diagnosed by USG at –
A. 10–12 weeks of gestation
B. 14–18 weeks of gestation
C. 20–24 weeks of gestation
D. 24–28 weeks of gestation
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Anencephaly
Question: Causes of polyhydraminos include:a) Diabetes mellitusb) Preeclampsiac) Esophageal atresiad) Renal agenesise) Anencephaly
A. acd
B. bde
C. cde
D. ace
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Anencephaly
Question: Anencephaly is best diagnosed at 12 weeks by :
A. Serum alpha fetoprotein
B. Ultrasonogram
C. Radiography
D. Amniography
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Anencephaly
Question: Anencephaly causes all except :
A. Prematurity
B. Face presentation
C. Hydramnios
D. None
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Anencephaly
Question: Which of the following is seen in Angelman Syndrome
A. Uniparental disomy of maternal Chromosome
B. Obesity
C. Defective genomic imprinting of maternal chromosome
D. All of the above
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Angelman Syndrome
Question: Aniridia is associated with
A. Retinoblastoma
B. Hepatoblastoma
C. Nephrobl astoma
D. Medulloblastoma
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Aniridia
Question: Aniridia is associated with -
A. Retinoblastoma
B. Hepatoblastoma
C. Nephroblastoma
D. Medulloblastoma
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Aniridia
Question: In which of the following conditions, Aniridia and Hemihypertrophy are most likely present -
A. Neuroblastoma
B. Wilm's tumour
C. Non-Hodgkin's lymphoma
D. Germ cell tumour
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Aniridia
Question: In which of the following conditions Aniridia and help hyperophy6 are most likely present
A. Nerublastoma
B. Wilms tumor
C. Non Hodgkin's lymphoma
D. Germ cell tumor
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Aniridia
Question: Aniridia is associated with:
A. Retinoblastoma
B. Hepatoblastoma
C. Nephroblastoma
D. Medulloblastoma
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Aniridia
Question: In which of the following conditions, Aniridia and Hemihyperophy are most likely present?
A. Neuroblastoma
B. Wilms' tumour
C. Non-Hodgkin's lymphoma
D. Germ cell tumour
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Aniridia
Question: In which of the following conditions, Aniridia and Hemihyperophy are most likely present ?
A. Neuroblastoma
B. Wilms' tumour
C. Non-Hodgkin's lymphoma
D. Germ cell tumour
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Aniridia
Question: Bacillus Anthrax is:
A. Gram positive cocci in cluster
B. Gram positive rods with square ends
C. Gram positive bacili with spherical ends
D. Gram negative cocci in cluster
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Anthrax
Question: Anthrax bacilli differs from anthracoid bacilli by being
A. Non-capsulated
B. Strict aerobe
C. Non-motile
D. Haemolytic colonies on blood agar
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Anthrax
Question: Immunoprophylaxis of leprosy includes-a)  BCGb)  MMRc)  ICRC bacillusd) Anthrax vaccinee) Mw
A. a
B. ac
C. ad
D. b
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Anthrax
Question: Anthrax bacilli differs from anthracoid bacilli by being -
A. Non-capsulated
B. Strict aerobe
C. Non-motile
D. Haemolytic colonies on blood agar
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Anthrax
Question: Which of the following antibodies is most frequently seen in Antiphospholipid Syndrome?
A. Beta 2 microglobulin antibody
B. Anti-nuclear antibody
C. Anti-centromere antibody
D. Anti- beta 2 glycoprotein antibody
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Antiphospholipid Syndrome
Question: Which of the following antibodies is most frequently seen in Antiphospholipid Syndrome? -
A. Anti- beta 2 glycoprotein antibody
B. Beta 2 microglobulin antibody
C. Anti-nuclear antibody
D. Anti-centromere antibody
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Antiphospholipid Syndrome
Question: Which of the following antibodies is most frequently seen in Antiphospholipid Syndrome ? -
A. Beta 2 microglobulin antibody
B. Anti-nuclear antibody
C. Anti-centromere antibody
D. Anti- beta 2 glycoprotein antibody
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Antiphospholipid Syndrome
Question: Which of the following antibodies is most frequently seen in Antiphospholipid Syndrome ?
A. Beta 2 microglobulin antibody
B. Anti-nuclear antibody
C. Anti-centromere antibody
D. Anti- beta 2 glycoprotein antibody
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Antiphospholipid Syndrome
Question: Apraxia is a disorder of:
A. Cerebellum
B. Sensory system
C. Motor system
D. Initiating and planning movement
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Apraxia
Question: Allergic bronchopulmonary Aspergillosis is commonly a complication of:
A. TB
B. Bronchogenic carcinoma
C. Cystic fibrosis
D. Wegener's granulomatosis
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Aspergillosis
Question: Diagnostic criteria for Allergic Bronchopulmonary Aspergillosis include all, except
A. Peripheral eosinophilia (>0.1 x 109/mm3)
B. Central bronchiectasis
C. Episodic Asthma
D. Detection of Aspergillus in sputum
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Aspergillosis
Question: Neurotropic fungus is/are -a) Cryptococcus neoformansb) Histoplasmosisc) Trichophytond) Candidae) Aspergillosis
A. abcd
B. bcde
C. abde
D. ade
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Aspergillosis
Question: Vascular involvement and thrombosis is seen in -a) Coccidioidomycosisb) Aspergillosisc) Mucormycosisd) Histoplasmosis
A. a
B. bc
C. ac
D. ad
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Aspergillosis, Mucormycosis
Question: Allergic Broncho-pulmonary Aspergillosis is commonly a complication of:
A. TB
B. Bronchogenic carcinoma
C. Cystic-fibrosis
D. Wegener's granulomatosis
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Aspergillosis
Question: Fungal infection in AIDS -a) Mucormycosisb) Aspergillosisc) Disseminated candidiasisd) Mucocutaneous candidiasis
A. ab
B. bc
C. cd
D. ac
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Aspergillosis, Mucormycosis
Question: End stage Lung disease seen in -a) Sarcoidosisb) Interstitial lung diseasec) Langerhans cell histiocytosisd) Aspergillosise) Asbestosis
A. bcde
B. abce
C. acde
D. abde
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Aspergillosis
Question: Aspergillosis can present with all except
A. Lung cavity
B. Ear infection
C. Normal component in sputum
D. Rhinocerebral involvement
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Aspergillosis
Question: The site of occurrence of Subependymal Giant Cell Astrocytoma is
A. Cerebellum
B. Pineal gland
C. Foramen of monro
D. Medulla Oblongata
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Astrocytoma
Question: Subependymal Gaint Cell Astrocytoma is commonly associated with which of the following condition?
A. Neurofibroma
B. Schwannoma
C. Ependymoma
D. Tuberous sclerosis
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Astrocytoma
Question: A Child presented with Adenoma sebaceum and intractable seizures. MRI showed sub ependymal giant cell Astrocytomas. Cause is
A. Tuberous sclerosis
B. Neurofibromatosis
C. Sturge Weber syndrome
D. Von-Hippel Lindau syndrome
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Astrocytoma
Question: Common spinal cord tumor with intradural but extramedullary situation -a)  Meningiomab)  Neurofibromac)  Ependymomad) Astrocytoma
A. ab
B. a
C. ad
D. bc
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Astrocytoma, Meningioma
Question: The gene responsible for Ataxia Telangiectasia is located on:
A. Chromosome 1
B. Chromosome 5
C. Chromosome 11
D. Chromosome 12
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Ataxia Telangiectasia
Question: All are false regarding Ataxia Telangiectasia EXCEPT:
A. Autosomal dominant
B. Prone for Development of Squamous Cell Carcinoma of Skin
C. Gene repair defect
D. Most common seen in adults
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Ataxia Telangiectasia
Question: Characteristic Auto antibodies of Autoimmune Hepatitis include all of the following, Except:
A. Antinuclear Antibodies (ANA)
B. Anti SLA
C. Anti LKMI
D. ANCA
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Autoimmune Hepatitis
Question: Babesiosis is transmitted by -
A. Tick
B. Mites
C. Flea
D. Mosquito
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Babesiosis
Question: Babesiosis is most commonly transmitted by:
A. Pigs
B. Rats
C. Sand fly
D. Ticks
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Babesiosis
Question: True about Babesiosis -
A. Caused by Babesia microtia
B. Resides in RBC
C. Resides in WBC
D. Chloroquine is the treatment of choice
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Babesiosis
Question: Babesiosis is transmitted by bite of:
A. Mosquito
B. Sandfly
C. Reduviid bug
D. Tick
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Babesiosis
Question: True about Babesiosis -a) Caused by Babesia microtib) Resides in RBCc) Resides in WBCd) Chloroquine is the treament of choicee) It is filarial parasite
A. ab
B. a
C. ad
D. bc
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Babesiosis
Question: Babesiosis is transmitted by ?
A. Tick
B. Mites
C. Flea
D. Mosquito
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Babesiosis
Question: Bejel is caused by -
A. T. pallidum
B. T. endemicum
C. T. pertenue
D. T. carateum
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Bejel
Question: Which of the following are histopathological features of Extra hepatic Biliary Atresia -a) Bile lakesb) Hepatocyte ballooning degenerationc) Marked bile duct proliferationd) Fibrosis of hepatic ducte) Parenchymal cholestasis
A. cde
B. acd
C. bde
D. ade
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Biliary Atresia
Question: Which of the following are histopathological features of Extra hepatic Biliary Atresia -
A. Bile lakes
B. Hepatocyte ballooning degeneration
C. Marked bile duct proliferation
D. All
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Biliary Atresia
Question: Blastomycosis is characterized by all except ?
A. Yeast like fungus
B. Commonly involves lung and skin
C. Dimorphic fungus
D. Common in South America
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Blastomycosis
Question: Blastomycosis is characterized by all except
A. Yeast like fungus
B. Commonly involves lung and skin
C. Dimorphic fungus
D. Common in South America
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Blastomycosis
Question: True about Bloom Syndrome -
A. Decreased IgG
B. Decreased IgM
C. IgA absent
D. Increased IgE
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Bloom Syndrome
Question: Botulism is a disease of ?
A. Neural transmission caused by the toxin of the bacterium clostridium botulinum
B. Muscular transmission caused by the toxin of the bacterium clostridium botulinum
C. Neuromuscular transmission caused by the toxin of the bacterium clostridium botulinum
D. Non neuromuscular transmission caused by the toxin of the bacterium clostridium botulinum
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Botulism
Question: Differential diagnosis of Botulism are all except -
A. GB syndrome
B. Myasthenia gravis
C. Lambe Eaton syndrome
D. Clostridial myonecrosis
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Botulism
Question: Botulism characterised by  a) Seizure  b) Fever  c) Ascending paralysis  d) Descending symmetrical paralysis  e) Blurring of vision
A. abc
B. bd
C. cde
D. de
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Botulism
Question: Clinical features of Botulism are all Except
A. Diarrhea
B. Dysarthria
C. Ocular nerve paralysis
D. Blurring of vision
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Botulism
Question: Botulism is most commonly seen with
A. Food with preservatives
B. Home canned food
C. Commercially canned food
D. Unpasteurized milk
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Botulism
Question: All of the following statements about Botulism are true except -
A. Botulism is caused by endotoxin
B. Honey ingestion causes infant botulism
C. Constipation is seen
D. Detection of antitoxin in the serum can aid in diagnosis
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Botulism
Question: All of the following statements about Botulism are true except :
A. Botulism is caused by endotoxin
B. Honey ingestion causes infant botulism
C. Constipation is seen
D. Detection of antitoxin in the serum can aid in diagnosis
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Botulism
Question: Botulism causes
A. Descending flaccid paralysis
B. Descending spastic paralysis
C. Ascending paralysis
D. Ascending spastic paralysis
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Botulism
Question: Clinical features of Botulism are all EXCEPT:
A. Diarrhoea
B. Constipation
C. Ocular nerve paralysis
D. Blurring of vision
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Botulism
Question: Botulism is a disease of
A. Neural transmission caused by the toxin of the bacterium clostridium botulinum
B. Muscular transmission caused by the toxin of the bacterium clostridium botulinum
C. Neuromuscular transmission caused by the toxin of the bacterium clostridium botulinum
D. Non neuromuscular transmission caused by the toxin of the bacterium clostridium botulinum
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Botulism
Question: All of the following statements about Botulism are true except
A. Botulism is caused by endotoxin
B. Honey ingestion causes infant botulism
C. Constpation is seen
D. Detection of antitoxin in the serum can aid in diagnosis
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Botulism
Question: Botulism is most commonly due to -
A. Egg
B. Milk
C. Meat
D. Canned vegetables
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Botulism
Question: Botulism is a disease of -
A. Neural transmission caused by the toxin of the bacterium Clostridium botulinum
B. Muscular transmission caused by the toxin of the bacterium Clostridium botulinum
C. Neuromuscular transmission caused by the toxin of the bacterium Clostridium botulinum
D. Non neuromuscular transmission caused by the toxin of the bacterium Clostridium botulinum
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Botulism
Question: Botulism is a disease of: -
A. Neural transmission caused by the toxin of the bacterium Clostridium botulinum
B. Muscular transmission caused by the toxin of the bacterium Clostridium botulinum
C. Neuromuscular transmission caused by the toxin of the bacterium Clostridium botulinum
D. Non neuromuscular transmission caused by the toxin of the bacterium Clostridium botulinum
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Botulism
Question: Which of the following is false about Botulism?
A. It is a type food poisoning
B. Botulinum toxin is a potent neurotoxin
C. It is an infection and not intoxication
D. The causative organism is Clostridium botulinum
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Botulism
Question: Botulism is most commonly due to
A. Egg
B. Milk
C. Meat
D. Pulses
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Botulism
Question: Botulism causes:
A. Descending flaccid paralysis
B. Descending spastic paralysis
C. Ascending paralysis
D. Ascending spastic paralysis
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Botulism
Question: Brucellosis can be transmitted by all EXCEPT
A. Contect with infected placenta
B. Ingestion of raw vegetables from infected farms
C. Person to person transmission
D. Inhalation of infected dust or aerosol
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Brucellosis
Question: Brucellosis can be transmitted by all of the following modes, except-
A. Contact with infected placenta
B. Ingestion of raw vegetables from infected forms
C. Person to person transmission
D. Inhalation of infected dust or aerosol
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Brucellosis
Question: Direct zoonose is -a)  Rabiesb)  Brucellosisc)  Taeniasisd)  Hydatid disease
A. ac
B. a
C. ad
D. ab
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Brucellosis, Rabies
Question: Brucellosis can be transmitted by all of the following modes, except:
A. Contact with infected placenta
B. Ingestion of raw vegetables from infected farms
C. Person to person transmission
D. Inhalation of infected dust or aerosol
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Brucellosis
Question: Regarding Brucellosis, all of these are true except-
A. Man to man transmission
B. A zoonosis
C. Blood cultures used in diagnosis
D. B melitensis is the most common cause
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Brucellosis
Question: Brucellosis can be transmitted by all of the following modes, except -
A. Contact with infected placenta
B. Ingestion of raw vegatable from infected farms
C. Person to person transmission
D. Inhalation of infected dust or aerosol
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Brucellosis
Question: Regarding Brucellosis, all of these are true except?
A. Man to man transmission
B. A zoonosis
C. Blood cultures used in diagnosis
D. B melitensis is the most common cause
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Brucellosis
Question: A farmer presenting with fever off and on for the past 4 years was diagnosed to be suffering from chronic Brucellosis. All of the following serological tests would be helpful in the diagnosis at this state except:
A. Standard agglutination test
B. 2-mercapto-ethanol test
C. Complement fixation test
D. Coomb's test
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Brucellosis
Question: Absolute lymphocytosis is seen in -a)  SLEb)  T.B.c) CLLd)  Brucellosis
A. abc
B. bcd
C. ac
D. bd
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Brucellosis
Question: False about Brucellosis
A. Also known as undulant  fever
B. B. melitensis is most virulent
C. Incubation period is 1-3 weeks
D. Antibiotic of choice is Ampicillin
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Brucellosis
Question: Brugada Syndrome is associated with:
A. Left Bundle Branch Block
B. Left Anterior Fascicular block
C. Left Posterior Fascicular block
D. Right Bundle Branch Block
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Brugada Syndrome
Question: Which of the following is the site of Venous Thrombosis in Budd Chiari Syndrome?
A. Infrahepatic inferior vena cava
B. Infrarenal inferior vena cava
C. Hepatic vein
D. Poal vein
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Budd Chiari Syndrome
Question: All of the following are features of SVC Syndrome except-
A. Facial swelling
B. Dilatation and congestion of neck veins
C. Headache
D. Hoarseness of voice
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: C Syndrome
Question: All of the following are features of SVC Syndrome except -
A. Facial swelling
B. Dilatation and congestion of neck veins
C. Headache
D. Hoarseness of voice
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: C Syndrome
Question: Caudal Regression Syndrome is seen in babies of mothers suffering from which of the following condition?
A. PIH
B. Anaemia
C. Cardiac disease
D. Gestational diabetes
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Caudal Regression Syndrome
Question: Which of the following agents is the drug of choice for Central Diabetes Insipidus -
A. Desmopressin
B. Demeclocycline
C. Thiazide Diuretics
D. Lithium
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Central Diabetes Insipidus
Question: CHARGE Syndrome includes?
A. Choanal atresia
B. Coloboma of eye
C. Ear anomalies
D. All of above
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: CHARGE Syndrome
Question: Chikungunya virus belongs to which family:
A. Enterovirus
B. Herpes virus
C. Toga virus
D. None of the above
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Chikungunya
Question: Group B (flaviviruses) Arboviruses is/are-a) Dengue feverb) Rift valley feverc) Chikungunya feverd) J.E.e) Yellow fever
A. acd
B. bde
C. ade
D. ad
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Chikungunya
Question: Chikungunya is trasmittedb ?
A. Aedes
B. Culex
C. Mansonoides
D. Anopheles
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Chikungunya
Question: Disease(s) transmitted by Aedes aegypti include – a) Yellow feverb) Denguec) Chikungunya feverd) West Nile fever e) Rift valley fever
A. bcde
B. abcd
C. acde
D. abce
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Chikungunya
Question: Chikungunya is transmitted by ?
A. Aedes
B. Culex
C. Mansonoides
D. Anopheles
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Chikungunya
Question: Chikungunya is transmitted by
A. Aedes
B. Culex
C. Mansonoides
D. Anopheles
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Chikungunya
Question: Chikungunya is caused by ?
A. Mosquito-borne Alphavirus
B. Mosquito-borne Beta virus
C. Mosquito-borne Gamma virus
D. Mosquito-borne Deltavirus
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Chikungunya
Question: Chikungunya is transmitted by -
A. Aedes
B. Culex
C. Mansonia
D. Anopheles
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Chikungunya
Question: Cholangiocarcinoma ?
A. Obesity
B. Opistorchissinensis infection
C. Salmonella carrier state
D. HBV infection
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholangiocarcinoma