guan-wang/ReDis-QA huggingface dataset:
Question: Cholangiocarcinoma is associated with -
A. Chlonorchis sinensis
B. Schistosoma
C. Plasmodium
D. None
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cholangiocarcinoma
Question: Cholangiocarcinoma histologically resembles ?
A. Sq. cell type
B. Schirrhous type
C. Columnar cell type
D. All
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholangiocarcinoma
Question: Cholangiocarcinoma has been associated with infection by:
A. Paragonimus westermani
B. Clonorchis sinensis
C. Loa Loa
D. Schistosoma haematobium
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholangiocarcinoma
Question: Cholangiocarcinoma is caused by -a) Fasciola infestationb) Clonorchis infestationc) Paragonimus infestationd) Ascaris infestatione) None of these
A. ac
B. ab
C. ad
D. bc
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholangiocarcinoma
Question: Which parasite causes Cholangiocarcinoma
A. Fasciola hepatica
B. Fasciola buski
C. Clonorchis sinensis
D. Paragonimus westermani
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cholangiocarcinoma
Question: Cholangiocarcinoma histologically resembles -
A. Sq. cell type
B. Colloid cell type
C. Schirrhous type
D. Columnar cell type
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cholangiocarcinoma
Question: Cholangiocarcinoma -
A. Obesity
B. Opistorchissinensis infection
C. Salmonella carrier state
D. HBV infection
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholangiocarcinoma
Question: Cholangiocarcinoma has been associated with infection by
A. Paragonimus westermani
B. Clonorchis sinensis
C. Loa Loa
D. Schistosoma haematobium
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholangiocarcinoma
Question: Cholangiocarcinoma histologically resembles
A. Squamous cell type
B. Colloid cell type
C. Schirrhous type
D. Columnar type
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cholangiocarcinoma
Question: According to Bismuth classification, type IV Cholangiocarcinoma involves
A. Common hepatic duct
B. Bifurcation only
C. Bifurcation and bilateral secondary intrahepatic ducts
D. Bifurcation and unilateral secondary intrahepatic ducts
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cholangiocarcinoma
Question: Cholangiocarcinoma most commonly metastases to-
A. Liver
B. Bones
C. Lung
D. Pancrease
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cholangiocarcinoma
Question: Carrier stage seen in -a)  Poliob)  Cholerac)  Pertusis d) Plague e)  Tetanus
A. da
B. abc
C. dea
D. ac
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholera, Plague
Question: Select inappropriate statement regarding Cholera
A. Incubation period 1-2 days
B. Rice - watery diarrhoea
C. Azithromycin is treatment of choice in adults
D. It is a notifiable disease locally, nationally and internationally
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cholera
Question: Cholera toxin irreversibly stimulates the cAMP-dependent pump in intestinal cells resulting in
A. Cl- rich watery diarrhea
B. K+ rich watery diarrhea
C. Na+ rich watery diarrhea
D. Ca+ rich watery diarrhea
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cholera
Question: Cholera is caused by?
A. Vibrio cholera.01
B. Enterococcus
C. V. Parahemolyticus
D. E.coli
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cholera
Question: Cholera toxin is due to -
A. Chromosome
B. Plasmid
C. Phage
D. Transposons
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cholera
Question: Cholera toxin acts by which mechanism?
A. Overactivates adenylate cyclase (cAMP) by permanently activating Gs
B. Mimics the adenylate cyclase enzyme (cAMP)
C. Overactivates guanylate cyclase (cGMP)
D. Inactivate elongation factor (EF-2)
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cholera
Question: Cholera vaccination is indicated -
A. To control epidemics
B. For travellers
C. In endemic areas
D. In Neonates
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cholera
Question: Cholera toxin binds to which receptors in intestine:
A. Sphingosine through A subunit
B. Sphingosine through B subunit
C. GM1 gangliosides through A subunit
D. GM1 gangliosides through B subunit
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Cholera
Question: True of 8th Pandemic of Cholera
A. Originated in 2012
B. Started in Bangladesh
C. Due to O139 El Tor
D. Low attack rate
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholera
Question: Cholera like symptoms is produced by which of the following poisons
A. Arsenic
B. Organophosphorus
C. Lead
D. Rat killer
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cholera
Question: Cholera vaccination is indicated ?
A. To control epidemics
B. For travellers
C. In endemic areas
D. In Neonates
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cholera
Question: Which of the following is enrichment media for Vibrio Cholera?
A. Venkatraman-Ramakrishnan medium
B. Cary-Blair medium
C. Autoclaved sea water
D. Alkaline peptone water
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Cholera
Question: Cholera toxin:
A. Increases the levels of intracellular cylic GMP
B. Acts through the receptor the opiates
C. Causes continued activation of adenylate cyclase
D. Inhibits the enzyme phosphodiesterase
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cholera
Question: True about V. Cholerae is -
A. One attack of V. Cholerae gives live-long immunity
B. Affects adults and children with equal propensity in non epidemic regions
C. Affects adults and children with equal propensity in non epidemic regions
D. Pathogencity of 0-139 vibrio is due to 0 antigen
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Cholera
Question: Cholera transmission by -a) Food transmitsb) Vaccination gives 90% efficiencyc) Healthy carrierd) Chlorination is not effective
A. a
B. bc
C. ac
D. b
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cholera
Question: No chemoprophylaxis for - a)  Typhoidb)  Chicken poxc)  Influenzad)  Cholera
A. b
B. ab
C. ab
D. bd
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholera, Typhoid
Question: Post exposure active immunization can be done fora)  Rabiesb)  Measlesc)  Cholerad)  Yellow fever
A. da
B. ab
C. da
D. ac
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholera, Measles, Rabies
Question: Cholera toxin effects are mediated by stimulation of which of the following second messengers -
A. cAMP
B. cGMP
C. Ca++ - Calmodulin
D. IP3 / DAG
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cholera
Question: "Cholera" is caused by:
A. Vibriocholera .01
B. Vibriocholera .001
C. Vibrio parahemolyticus
D. Vibriocholera .0001
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cholera
Question: Cholera like diarrhea is associated with?
A. Copper poisoning
B. Arsenic poisoning
C. Lead poisoning
D. Mercury poisoning
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholera
Question: Cholera vaccine effectiveness is -
A. 20% for 12 months
B. 50% for 12 months
C. 20% for 36 months
D. 50% for 36 months
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholera
Question: Cholera toxin effects are mediated by stimulation of which of the following second messengers
A. cAMP
B. cGMP
C. Ca44 -calmodulim
D. IP3/ DAG
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cholera
Question: Pandemic are caused by -a)  Hepatitis Bb)  Influenza-Ac)  Influenza-Bd)  Influenza-Ce) Cholera
A. bd
B. be
C. bcd
D. da
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholera
Question: Hemolytic uremic syndrome is caused by -a) EIECb) Shigella c) Salmonellad) Cholerae) Klebsiella
A. a
B. bc
C. ac
D. ad
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholera
Question: Cholera toxin –
A. increase the levels of intracellular cyclic GMP
B. Act through opiate receptor
C. causes continued activation of adenyl cyclase
D. inhibit the enzyme phosphodiesterase
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cholera
Question: Which of the following is not a Cholera vaccine?
A. Ty21a
B. CVD-103-HgR
C. WC-rBS
D. mORC-Vax
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cholera
Question: Cholera toxin binds to which receptors in intestine-
A. Sphingosine through A subunit
B. Sphingosine through B subumit
C. GM1 gangliosides through A subunit
D. GM1 gangliosides through B subunit
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Cholera
Question: Cholera transmission by -
A. Food transmits
B. Vaccination gives 90% efficiency
C. Healthy carrier
D. Chlorination is nor effective
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cholera
Question: Cholera patient having stool output 1000-1500 mL/day is known as:
A. Cholera mitis
B. Cholera dumdum
C. Cholera magna
D. Cholera gravis
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Cholera
Question: Cholera presents with symptoms mimicking: TN 10
A. Arsenic poisoning
B. Dhatura poisoning
C. Barbiturate poisoning
D. Morphine poisoning
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cholera
Question: Cholera toxin -
A. Increases the levels of intracellular cylic GMP
B. Acts through the receptor the opiates
C. Causes continued activation of adenylate cyclase
D. Inhibits the enzyme phosphodiesterase
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cholera
Question: Cholera toxin acts by -
A. Na ATPase inhibition
B. Adenylate cyclase stimulation
C. Opening of chloride channel
D. Stimulation of Ca' channel
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholera
Question: Cholera is caused by-
A. V.cholerae O1
B. V.cholerae O1 and O139
C. V. cholerae O139
D. NAG vibrios
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cholera
Question: Cholera prophylaxis is by -
A. Doxycycline 300mg OD
B. Cephalosporin
C. Streptomycin
D. Cotrimoxazole
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cholera
Question: Cholera toxin-
A. Increases the levels of intracellular cylic GMP
B. Acts through the receptor the opiates
C. Causes continued activation of adenylate cyclase
D. Inhibits the enzyme phosphodiesterase
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cholera
Question: Which of the following diseases have incubation period < 10 days -a)  Cholerab)  Influenzac)  Plagued)  Measlese) Rubella
A. ab
B. bc
C. abc
D. bcd
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cholera, Measles, Plague, Rubella
Question: Superantigens area) Erythrotoxin of Staph. aureusb) Clostridium difficile toxinc) Staphyloccocal toxic shock syndrome toxind) Cholera toxin
A. a
B. bc
C. ad
D. ac
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Cholera
Question: Giant cells seen in -a)  Osteoclastomab)  Chondroblastomac)  Chordomad)  Osteitis fibrosa cystica
A. ac
B. ab
C. ad
D. bc
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Chordoma
Question: Chordoma can occur over all the following sites, except -
A. Rib
B. Clivus
C. Sacrum
D. Vertebral body
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Chordoma
Question: Chordoma commonly involves -a) Dorsal spineb) Clivusc) Lumbar spined) Sacrume) Cervical spine
A. bd
B. d
C. ab
D. ac
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Chordoma
Question: All of the following are true about Chronic Lymphocytic Leukemia, Except:
A. Diagnosed on routine blood tests
B. Leukocytosis is prominent
C. Can present as acute leukemia
D. T lymphocyte CLL is more common
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Chronic Lymphocytic Leukemia
Question: Which of the following is more frequently seen in Churg Strauss Syndrome in comparison to Wegener's Granulomatosis
A. Renal involvement
B. Lower Respiratory Tract involvement
C. Eye involvement
D. Upper Respiratory Tract involvement
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Churg Strauss Syndrome
Question: All of the following statements about Churg Strauss Syndrome are true, except:
A. Marked Eosinophilia
B. Mononeuritis multiplex is common
C. Renal failure is common
D. Often associated with Allergic Rhinitis
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Churg Strauss Syndrome
Question: False statement regarding Complex Regional Pain Syndrome (CRPS) is?
A. Type 1 CRPS occurs following a nerve injury
B. Type 1 CRPS is also called as Reflex Sympathetic Dystrophy
C. It occurs due to adrenergic sensitivity of afferent nociceptors
D. CRPS Type 1 resolves with symptomatic treatment
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Complex Regional Pain Syndrome
Question: Congenital Adrenal Hyperplasia is due to deficiency of:
A. 21 beta hydroxylase
B. 17 alpha hydroxylase
C. 5 alpha reductase
D. 17 beta reductase
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Congenital Adrenal Hyperplasia
Question: A pregnant mother presents with history of delivery of a previous child with Congenital Adrenal Hyperplasia (CAH). The best management protocol for the current pregnancy is:
A. To sta prednisolone after establishing whether fetus is affected by Chorionic Villous Sampling
B. To sta dexamethasone as soon as pregnancy is confirmed
C. To sta dexamethasone after determining sex of the fetus by Karyotyping
D. To sta prednisolone after determining sex of the fetus with USG
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Congenital Adrenal Hyperplasia
Question: Which condition is associated with Congenital Adrenal Hyperplasia?
A. Male pseudohermaphroditism
B. Female pseudohermaphroditism
C. Female true hermaphroditism
D. Sequential pseudohermaphroditism
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Congenital Adrenal Hyperplasia
Question: All are true regarding Congenital Syphilis except:
A. Procaine Penicillin can prevent it satisfactorily
B. Infection of the fetus most commonly occurs in 1st trimester
C. Neurological damage with mental retardation can be a serious consequence
D. If mother has late syphilis, chances of transmission decreases
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Congenital Syphilis
Question: All the following are true of Craniopharyngioma except -
A. Derived from Rathke's pouch
B. Contains epithelial cells
C. Present in sella or infrasellar location
D. Causes visual disturbances
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Craniopharyngioma
Question: Third nerve palsy with pupillary sparing is seen in-a) Hypertensionb) Aneurysm of posterior communicating arteryc) Diabetes mellitusd) Craniopharyngioma
A. a
B. bc
C. ad
D. ac
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Craniopharyngioma
Question: All are true about Craniopharyngioma except?
A. Solid-cystic lesion
B. Commonly calcifies in adults
C. Admantinomatous type is common in children
D. Machine oily protein rich content
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Craniopharyngioma
Question: Commonest location for Craniopharyngioma is
A. Intrasellar
B. Suprasellar
C. Intraventricular
D. Intracerebral
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Craniopharyngioma
Question: A six year old child managed by complete surgical removal of Craniopharyngioma developed multiple endocrinopathies. Which of following hormones should be replaced first?
A. Hydrocoisone
B. Growth hormone
C. Thyroxine
D. Prolactin
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Craniopharyngioma
Question: All are true regarding Craniopharyngioma except?
A. Derived from Rathke's pouch
B. Contains epithelial cells
C. Present in temporal or parietal lobes
D. Causes visual disturbances
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Craniopharyngioma
Question: A 7 yr old boy underwent neurosurgery for Craniopharyngioma following which pituitary functions were lost. Which of the following hormone should be replaced first?
A. Hydrocoisone
B. Thyroxine
C. Growth hormone
D. Prolactin
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Craniopharyngioma
Question: All of the following are true for Craniopharyngioma except?
A. Derived from Rathke's pouch
B. Can lead to central DI
C. Present in sellar or infrasellar location
D. Causes visual disturbances
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Craniopharyngioma
Question: Craniopharyngioma arises from -
A. Pituitary stalk
B. Posterior pituitary
C. Pineal gland
D. Cerebellum
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Craniopharyngioma
Question: All of the following statements regarding Craniopharyngiomas are true, except :
A. Arise from Rathke's pouch
B. Can cause visual disturbances
C. Presents with hypopituitarism in adults
D. Usually Infrasellar in location
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Craniopharyngioma
Question: True precocious puberty can occur in all, except –a) McCune Albright syndromeb) Craniopharyngiomac) Congenital adrenal hyperplasiad) Hypothalamic hamartoma
A. a
B. bc
C. ac
D. b
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Craniopharyngioma
Question: All the following are true of Craniopharyngioma except
A. Derived from Rathke's pouch
B. Contains epithelial cells
C. Present in sella or infra-sellar location
D. Causes visual disturbances
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Craniopharyngioma
Question: Lung granuloma with necrosis are seen in -a)  PANb)  TBc)  Histoplasmosisd) Cryptococcosise)  Wegener's granulomatosis
A. bce
B. bc
C. acd
D. ace
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cryptococcosis
Question: Most common presentation of Cryptococcosis is
A. Meningitis
B. Pulmonary cryptococcosis
C. SKin lesions
D. Osteomyelitis
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cryptococcosis
Question: Criteria included in AIDS surveillance definition include -a) Extrapulmonary TB b) Cryptococcosisc)  Candidiasisd)  Leptospirosis e)  Kaposi sarcoma
A. bcde
B. abce
C. acde
D. abde
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Cryptococcosis, Leptospirosis
Question: Primary site of infection in Cryptococcosis is
A. Adrenal glands
B. Bone
C. Central nervous system
D. Lungs
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Cryptococcosis
Question: The most common cause of pulmonary abscesses in Cystic Fibrosis is?
A. Pseudomonas aeruginosa
B. Staphylococcus aureus
C. Burkholderia cenocepacia
D. Nontuberculous mycobacteria
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cystic Fibrosis
Question: Cysticercosis cellulosae causes infection with
A. Taenia saginata
B. Echinococcus granulosus
C. Taenia solium
D. Diphyllobothrium latum
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cysticercosis
Question: Cerebral Cysticercosis
A. Commonly manifests with localizing signs
B. May present with dementia
C. Rarely occurs in children
D. Usually presents with generalized seizures
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cysticercosis
Question: Cysticercosis is caused by larva of:
A. Taenia solium
B. T. saginata
C. Echinococcus
D. Ascaris
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cysticercosis
Question: Cysticercosis present as : a)  Seizuresb)  Neuropathyc)  Encephalitisd)  Muscular hypertrophy
A. a
B. bc
C. ac
D. b
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cysticercosis
Question: Cysticercosis present as  a) Seizure  b) Neuropathy  c) Encephalitis  d) Muscular hypertrophy
A. abc
B. abd
C. bcd
D. bd
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cysticercosis
Question: Cysticercosis is caused by:
A. T. Solium
B. T. Saginata
C. A. duodenale
D. E. granulosus
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cysticercosis
Question: Which of the following is not true about Cystinosis?
A. Cysteine stones in urine common
B. Corneal crystals
C. Fanconi syndrome
D. White blond hair and photophobia
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cystinosis
Question: In Cystinuria, all of the following amino acids are excreted in urine, except:-
A. Cystine
B. Ornithine
C. Leucine
D. Arginine
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cystinuria
Question: Cystinuria is associated with excretion of which amino acid in urine
A. Cystine, lysine, Tyrosine and alanine
B. Cystine, lysine, ornithine and alanine
C. Cystine, ornithine, lysine and arginine
D. Cystine, ornithine, leucine and arginine
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cystinuria
Question: Cystinuria presents with excess of
A. Cysteine
B. Tyrosine
C. Glutamine
D. Valine
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Cystinuria
Question: Cystinuria all of the following amino acids are excreted, except:
A. Cystine
B. Ornithine
C. Leucine
D. Arginine
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Cystinuria
Question: Cystinuria is characterised by –
A. Generalised aminoaciduria
B. Systemic acidosis
C. Deposition of cystine crystals in Renal tubular cells
D. Recurrent urinary caliculi
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Cystinuria
Question: The best way to manage Dermatitis Herpetiformis is ?
A. Gluten free diet with minerals and vitamins
B. Dapsone
C. Acyclovir
D. Steroids
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Dermatitis Herpetiformis
Question: Which one of the following is the treatment of choice for Dermatitis Herpetiformis?
A. Corticosteroids
B. Dapsone
C. Methotrexate
D. Retinoids
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Dermatitis Herpetiformis
Question: Dermatomyositis test of choice -
A. CPK
B. 24hr urine creat
C. SGOT
D. SGPT
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Dermatomyositis
Question: True about Dermatomyositis is?
A. Associated with HLA B27
B. Bimodal age distribution
C. No involvement of joints
D. Myopathy precedes skin lesions in most cases
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Dermatomyositis
Question: Common antibody in Polymyositis and Dermatomyositis includes
A. SS-7
B. SS-8
C. Anti-aminoacyl-tRNA synthetase
D. Anti hystidyl transfer synthetase
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Dermatomyositis
Question: All of the following signs are seen in Dermatomyositis except
A. Heliotrope sign
B. Gottron sign
C. Dimple sign
D. Shawl sign
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Dermatomyositis
Question: Dracunculosis infection occurs through-
A. Ingestion of water containing cyclops
B. Ingestion of water containing the parasite
C. Ingestion of fish
D. Penetration of skin
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Dracunculosis
Question: WHO considerations regarding Dracunculosis eradication, all are true except
A. DDT
B. Drinking piped water and installation of hand pumps
C. Health education and awareness of public
D. Control of Cyclops
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Dracunculosis
Question: Dracunculosis is most common in -
A. Gujarat
B. Rajasthan
C. Madhya Pradesh
D. Orissa
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Dracunculosis
Question: Dracunculosis is most common in-
A. Gujarat
B. Rajasthan
C. Madhya Pradesh
D. Orissa
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Dracunculosis
Question: Candidates (s) for global eradication by WHO
a. Malariab. Dracunculosis c. Polio d. Measles e. Chicken pox
A. ab
B. abd
C. abc
D. bcd
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Dracunculosis, Malaria, Measles
Question: Dracunculosis infection occurs through?
A. Ingestion of water containing cyclops
B. Ingestion of water containing the parasite
C. Ingestion of fish
D. Penetration of skin
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Dracunculosis
Question: Dracunculosis infection occurs through -
A. Ingestion of water containing cyclops
B. Ingestion of water containing the parasite
C. Ingestion of fish
D. Penetration of skin
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Dracunculosis
Question: Duane syndrome involves
A. Superior oblique
B. Inferior oblique
C. Lateral rectus
D. Superior rectus
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Duane syndrome
Question: Duchenne Muscular Dystrophy is a disease of:
A. Neuromuscular junction
B. Sarcolemmal proteins
C. Muscle contractile proteins
D. Disuse atrophy due to muscle weakness
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Duchenne Muscular Dystrophy
Question: Duchenne Muscular Dystrophy is a disease of-
A. Neuromuscularj unction
B. Sarcolemmal proteins
C. Muscle contractile proteins
D. Disuse atrophy due to muscle weakness
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Duchenne Muscular Dystrophy
Question: Duchenne Muscular Dystrophy is a disease of –
A. Neuromuscular junction
B. Sarcolemmal proteins
C. Muscle contractile proteins
D. Disuse atrophy due to muscle weakness
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Duchenne Muscular Dystrophy
Question: Simplex type of Epidermolysis Bullosa involves mutations in
A. Keratin 5
B. Lamina lucida
C. Type vII collagen
D. Dystrophin
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Epidermolysis Bullosa
Question: Epidermolysis Bullosa simplex is because of defect in:
A. Collagen 7
B. Keratin 5 and Keratin 14
C. Laminin
D. BP1 and BP2
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Epidermolysis Bullosa
Question: The minimum number of polyps necessary for a diagnosis of Familial Adenomatous Polyposis (FAP) is:
A. 5
B. 10
C. 50
D. 100
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Familial Adenomatous Polyposis
Question: Inheritance of "Familial Hypercholesterolemia" is:
A. AD
B. AR
C. X Linked dominant
D. X linked recessive
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Familial Hypercholesterolemia
Question: Which of the following is the inheritance pattern of Familial Hypercholesterolemia?
A. Autosomal dominant
B. Autosomal recessive
C. X Linked dominant
D. X Linked recessive
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Familial Hypercholesterolemia
Question: Fetal Hydantoin Syndrome is caused by:
A. Phenytoin
B. Alcohol
C. Tetracycline
D. Sodium valproate
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Fetal Hydantoin Syndrome
Question: X-rays findings of "Fibrous Dysplasia" is:
A. Ground glass density
B. Calcifications
C. Coical thickening
D. Bony expansion
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Fibrous Dysplasia
Question: X-rays findings of Fibrous Dysplasia is:
A. Ground glass density
B. Calcifications
C. Coical thickening
D. Bony expansion
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Fibrous Dysplasia
Question: In context with Filariasis, all are true except:
A. Definitive host is man
B. Worm colonize the lymphatic system
C. Most common causative agent is W. bancrofti
D. Transmitted by Aedes aegypti mosquito
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Filariasis
Question: Filariasis is cuased due to lymphatic obstruction by -
A. R vivax
B. V. bancrofti
C. C. sinerses
D. S. hemetabium
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Filariasis
Question: Culex mosquito is associated with the transmission of-a) Malariab) Filariasisc) Dengued) Japanese encephalitise) Typhus
A. c
B. d
C. bd
D. ac
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Filariasis, Malaria
Question: All of the following are helpful for elimination of Filariasis, except -
A. Microfilaris do not multiply in vectors
B. They multiply in humans
C. Larvae are deposited on skin surface where they can't survive
D. NOne
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Filariasis
Question: The Clinical incubation period of Filariasis is
A. 10 to 20 days
B. 3 to 6 months
C. 8 to 16 months
D. 6 to 12 months
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Filariasis
Question: All are true regarding Lymphatic Filariasis except
A. Causative agent - Wuchereria bancrofti
B. Intermediate host - Man
C. Main vector in India - Culex quinquefasciatus
D. Most common epidemiological method for detection - thick film preparation
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Filariasis
Question: Filariasis involves
A. Only superficial lymphatics
B. Only deep lymphatics
C. Both superficial and deep lymphatics
D. Only skin
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Filariasis
Question: Treatment for Filariasis is,
A. Chloroquin
B. Diethyl Carbamazine
C. Tetracycline
D. Praziquantel
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Filariasis
Question: Fox Fordyce Disease effects:
A. Sebaceous glands
B. Eccrine Glands
C. Apocrine glands
D. Any gland
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Fox Fordyce Disease
Question: Classic Galactosemia is due to deficiency of:
A. Hexosaminidase
B. Glucocerebroside
C. Sphingomyelinase
D. Galactose-1-Phosphate-Uridyl-Transferase
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Galactosemia
Question: The MOST common enzyme deficiency responsible for Galactosemia is related to which of the following enzymes?
A. UDP galactose epimerase
B. Galactokinase
C. Galactosidase
D. Galactose-l-phosphate uridyl transferase
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Galactosemia
Question: What is the type of Galactosemia cataract?
A. Snowflake
B. Oil drop
C. Blue dot
D. Polychromaticlustre
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Galactosemia
Question: Galactosemia is due to deficiency of the following enzymes
A. Galactose-1-phosphate uridyl transferase
B. HGPRT
C. Galactokinase
D. Epimerase
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Galactosemia
Question: Galactosemia is due to the deficiency of:
A. Galactose-1-Phosphatase
B. Glucose-1-Phosphatase
C. Galcatose-1-Phosphate uridyl transferase
D. Glucose-6-Phosphatase
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Galactosemia
Question: The enzyme deficient in Galactosemia is:-
A. Sphingomyelinase
B. Hexosaminidase
C. Galactose 1- phosphate uridyl transferase
D. Glucocerebrosidase
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Galactosemia
Question: The enzyme deficient in Galactosemia is:
A. Hexoseaminidase B
B. Hexosaminidase A
C. Galactose 1 phosphate uridyltransferase
D. Glucocerebrosidase
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Galactosemia
Question: Most common enzyme deficiency responsible for Galactosemia is?
A. UDP galactose epimerase
B. Galaktokinase
C. Galactosidase
D. Galactose-l-phosphate uridyl transferase
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Galactosemia
Question: Galactosemia commonly is due to deficiency of
A. Galactose-1 phosphate uridyl transferase
B. Galactose-1 phosphatase
C. Glucose-1 phosphatase
D. Glucose-6 phosphatase
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Galactosemia
Question: Galactosemia enzyme defect:
A. Fructokinase
B. Glucokinase
C. Galactose 1 Phosphate Uridyl transferase
D. Glucose 6 Phosphatase
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Galactosemia
Question: All of the following are true about Galactosemia EXCEPT?
A. Galactose 1 phosphate and galactitol have toxic effects on various organs
B. Patients are symptomatic immediately after bih
C. Jaundice and liver dysfunction commonly seen
D. E.coli sepsis is an impoant cause of moality
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Galactosemia
Question: All of the following tests can help in the diagnosis of Galactosemia EXCEPT?
A. GALT assay
B. Mutation analysis
C. Benedicts test
D. Guthrie's test
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Galactosemia
Question: Intrahepatic cholestasis is seen in – a)  Galactosemiab)  Hypercalcemiac)  Haemoclu–omatosisd)  Cystic fibrosis
A. ad
B. c
C. ac
D. ab
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Galactosemia
Question: Enzyme deficiency in Galactosemia:
A. Galactose 1 phosphate uridyl transferase
B. Aldolase B
C. UDP galactose 4 epimerase
D. Fructokinase
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Galactosemia
Question: Which of the following agents is recommended for treatment of Gastrointestinal Stromal Tumors (GIST) -
A. Sorafenib
B. Imatinib
C. Gefitinib
D. Erlotinib
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Gastrointestinal Stromal Tumors
Question: What is false regarding Gastroschisis & omphalocele:
A. Intestinal obstruction is common in gastroschisis
B. Gastroschisis is associated with multiple anamolies
C. Umbilical cord is attached in normal position in gastroschisis
D. Liver is the content of omphalocele
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Gastroschisis
Question: Gastroschisis is associated with :
A. Younger maternal age
B. Maternal obesity
C. Elderly primi
D. Anaemia
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Gastroschisis
Question: Regarding Gastroschisis and omphalocele which of the following statement is false?
A. Intestinal obstruction is common in Gastroschisis
B. Liver is content of Omphalocele
C. Gastroschisis is associated with multiple anomalies
D. Umbilical cord is attached in normal position in Omphalocele
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Gastroschisis
Question: TRUE about Gestational Trophoblastic Disease is?
A. Most common site of metastasis is vagina
B. Presence of Lung metastasis classifies as stage 4 GTN
C. Liver metastasis carries a poor prognosis similar to brain metastasis
D. GTN following a term pregnancy has a better prognosis than that with previous molar pregnancy
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Gestational Trophoblastic Disease
Question: The highest incidence of Gestational Trophoblastic Disease is in :
A. Australia
B. Asia
C. Noh America
D. Western Europe
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Gestational Trophoblastic Disease
Question: Prognosis of Gestational Trophoblastic Disease depends on all, except :
A. Number of living children
B. Blood group
C. Parity
D. Previous HCG titre
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Gestational Trophoblastic Disease
Question: Glioblastoma multiforme may occur in the following except -
A. Cerebrum of adult
B. Brain stem of child
C. Spinal cord of adult
D. Adrenal medulla of child
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Glioblastoma
Question: Glioblastoma multiforme may occur in the following except:
A. Cerebrum of adult
B. Brain stem of child
C. Spinal cord of adult
D. Adrenal medulla of child
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Glioblastoma
Question: Which of the following is not true about Glioblastoma..
A. Also known as Butterfly tumor
B. Frontal lobe of the brain is common location
C. It belongs to WHO grade 3 Astrocytoma
D. Serpentine necrosis and glomeruloid bodies
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Glioblastoma
Question: Which of the following are orbital tumours a) Glioma    b) Lymphoma   c) Chloroma  d) Meningioma  e) Schwannoma
A. abcde
B. abd
C. abc
D. acd
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Glioma, Meningioma
Question: Glioma of optic nerve is associated with ?
A. Neurofibromatosis type I
B. Neurofibromatosis type II
C. Both the above
D. None of the above
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Glioma
Question: Glioma of the optic nerve is usually –
A. Gemistocytic
B. Pilocytic
C. Fibrillary
D. Lamellar
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Glioma
Question: Receptor on neural membrane that induces development of Glioma-
A. CD133
B. CD33
C. CD48
D. CD44
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Glioma
Question: Glioma of the optic nerve is associated with -
A. Neurofibromatosis type 1
B. Neurofibromatosis type II
C. Both the above
D. None of the above
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Glioma
Question: All of the following are features of Hemophagocytic Lymphohistiocytosis (HLH), except:
A. Fever
B. Splenomegaly
C. Hyperferritinemia
D. Hyperfibrinogenemia
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Hemophagocytic Lymphohistiocytosis
Question: Patients with 'Hemophilia A' have bleeding disorder because of -
A. Lack of platelet aggregation
B. Lack of reaction accelerator during activation of factor X in coagulation cascade
C. Neutralization of antithrombin III
D. Release of Thromboxane A2
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Hemophilia A
Question: Hemophilia A due to deficiency of
A. Factor VIII
B. Factor IX
C. Factor X
D. Factr XI
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hemophilia A
Question: Which of the following true regarding Hemophilia A
A. Serum levels of factor VIII are decreased
B. Deficiency of factor IX
C. PT increased
D. FIT decreased
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hemophilia A
Question: Hemophilia A has following except -
A. ↓ VIII factor
B. ↑PTT
C. ↑PT
D. Normal BT
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Hemophilia A
Question: Bleeding disorder with ↑ a PTT is/are -a) Hemophilia Ab) Hemophilia Bc) Henoch-schonlein purpurad) Bernard-soulier syndromee) Von-Willebrand disease
A. abe
B. bcd
C. cde
D. acd
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hemophilia A, Hemophilia B
Question: Hemophilia A results due to deficiency of which of the factors:
A. II
B. VII
C. VIII
D. XI
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Hemophilia A
Question: Which of the following is a recently approved monoclonal antibody for treatment of Hemophilia A?
A. Emicizumab
B. Sarilumab
C. Abaloparatide
D. Durvalumab
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hemophilia A
Question: Type of DCIS Which of the following true regarding Hemophilia A?
A. Serum levels of factor VIII are decreased
B. Deficiency of factor IX
C. PT increased
D. PPT decreased
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hemophilia A
Question: Hemophilia A is caused due to deficiency of
A. Factor X
B. Factor XI
C. Factor IX
D. Factor VIII
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Hemophilia A
Question: The most common manifestation of moderate /severe Hemophilia A is:
A. Recurrent Hemahrosis
B. Recurrent muscle bleeding
C. Recurrent bleeding from gums
D. Recurrent Hematuria
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hemophilia A
Question: Hemophilia A has increased:
A. PT
B. PTT
C. PT & PTT
D. None
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Hemophilia A
Question: Hemophilia B is deficiency of which factor:September 2007
A. IX
B. XII
C. VIII
D. X
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hemophilia B
Question: Hemophilia B is due to deficiency of -
A. Factor VIII
B. Factor VII
C. Factor IX
D. factor X
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Hemophilia B
Question: Hemophilia B is due to deficiency of:
A. Factor VIII
B. Factor VII
C. Factor IX
D. Factor X
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Hemophilia B
Question: In Hemophilia B what is most common cause of death?
A. Hemorrhage
B. HIV, HBV, HCV due to transfusions
C. Transfusion reactions
D. Deep vein thrombosis
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hemophilia B
Question: Hemophilia B is due to deficiency of-
A. Factor VIII
B. Factor VII
C. Factor IX
D. factor X
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Hemophilia B
Question: Hemophilia B is due to:
A. Factor VII deficiency
B. Factor IX deficiency
C. Platelet deficiency
D. Vit C deficiency
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Hemophilia B
Question: Hemophilia B is deficiency of which factor: September 2007
A. IX
B. XII
C. VIII
D. X
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hemophilia B
Question: Hepatic Encephalopathy is predisposed by all, Except:
A. Hyperkalemia
B. Dehydration
C. Constipation
D. GI Bleeding
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hepatic Encephalopathy
Question: Hepatitis D virus (delta agent) is a defective virus that can replicate only in cells already infected with which of the following viruses?
A. Hepatitis A virus
B. Epstein-Barr virus
C. Hepatitis G virus
D. Hepatitis B virus
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Hepatitis D
Question: Most common mutation in Hereditary Spherocytosis is
A. Band 3
B. Ankyrin
C. Spectrin
D. Band 4.2
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Hereditary Spherocytosis
Question: Which of the following is not seen in'Hereditary Spherocytosis:
A. Direct Coomb's Positive
B. Increased Osmotic Fragility
C. Splenomegaly
D. Gall Stones
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hereditary Spherocytosis
Question: Which of the following is not seen in Hereditary Spherocytosis
A. Direct Coomb's Positive
B. Increased Osmotic Fragility
C. Splenomegaly
D. Gall stones
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hereditary Spherocytosis
Question: Cleft lip, polydactyly, Holoprosencephaly are characteristic feature of?
A. Down syndrome
B. Edward syndrome
C. Patau syndrome
D. Turners syndrome
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Holoprosencephaly
Question: NOT a feature of Holt Oram Syndrome is
A. Absent Radius
B. Atrial septal defect
C. Thrombocytopenia
D. Autosomal dominant inheritance
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Holt Oram Syndrome
Question: Treatable causes of dementia are -a) Alzheimer's ds.b) Hypothyroidismc) Multi-infarct dementia d) SDH (subdural h'ge) e) Hydrocephalus
A. abc
B. ade
C. bde
D. bce
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Hydrocephalus
Question: Reversible cause of dementia -a) Post encephalitisb) Multi infarctc) Hydrocephalusd) Senile dementia
A. a
B. bc
C. ad
D. ac
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Hydrocephalus
Question: Causes of breech presentation are:a) Hydrocephalusb) Oligohydramniosc) Pelvic contracture d) Placenta praevia
A. acd
B. ad
C. bc
D. bde
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hydrocephalus
Question: Hydrocephalus in the fetus is diagnosed by all except :
A. Large fontanelle with widely separated sutures as felt on PV examination
B. High floating head
C. Serial ultrasound
D. CPD
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Hydrocephalus
Question: In Hydrocephalus ex vacuo, the compensatory enlargement of ventricles and an increase in CSF volume due to brain atrophy is seen in-
A. Alzheimers diseae
B. Picks diseases
C. Both
D. None of the above
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Hydrocephalus
Question: Normal pressure Hydrocephalus is characterized by all except -
A. Aphasia
B. Dementia
C. Ataxia
D. Urinary incontinence
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hydrocephalus
Question: In Hydrocephalus exvacuo, the compensatory enlargement of ventricles and increase in CSF volume due to brain atrophy is seen in-
A. Alzheimers diseae
B. Picks diseases
C. Both
D. None of the above
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Hydrocephalus
Question: Hydrocephalus is detailed best antenatally by –
A. X-ray abdomen
B. Amniocentesis
C. Clinical examination
D. Ultrasonography
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Hydrocephalus
Question: Disease having autosomal recessive inheritance -a) Cystic fibrosisb)  Hydrocephalusc)  Duchene muscular dystrophyd) Albinisme)  Vitamin D resistant ricket
A. b
B. ad
C. ac
D. ab
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Hydrocephalus
Question: Hair on end appearance is seen in X–ray skull in –a)  Thalassemiab)  Hydrocephalusc)  Chronic malariad)  Sickle cell anemia
A. ad
B. c
C. ac
D. ab
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hydrocephalus
Question: Which of the following is true about TB meningitis-a) Exudates are formed on the convexities of brainb) CSF stored at 4°C in the time of transportationc) Hydrocephalus is common sequalaed) Meningoencephalitis is common manifestation
A. abc
B. bcd
C. ac
D. bd
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Hydrocephalus
Question: Treatment of Congenital Hydrocephalus is
A. Stereotactic Surgery
B. Diuretics
C. Radiotherapy
D. VP shunt
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Hydrocephalus
Question: Normal pressure Hydrocephalus is characterized by all except:
A. Aphasia
B. Dementia
C. Ataxia
D. Urinary incontinence
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hydrocephalus
Question: Investigation of choice for Hydrocephalus in infants ?
A. Cranial USG
B. CT Scan
C. MRI
D. X-ray skull
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hydrocephalus
Question: Hydrocephalus is best detected antenately by:
A. X-ray abdomen
B. Amniocentesis
C. Clinical examination
D. Ultrasonography
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Hydrocephalus
Question: Hypokalemia is not present in :
A. Vomiting
B. Diarrhoea
C. Patient on diuretics
D. Chronic renal failure
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Hypokalemia
Question: A patient with Hypeension presents with Hypokalemia. Aldosterone levels and Renin levels are both elevated. The most likely diagnosis is
A. Renal Aery stenosis
B. Primary Hyperaldosteronism {Conn's syndrome}
C. Addison's disease
D. Cushing's syndrome
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hypokalemia
Question: Hypokalemia is defined as a plasma potassium concentration of
A. < 3.5 mmol/L
B. < 3.6 mmol/L
C. < 3.7 mmol/L
D. < 3.8 mmol/L
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hypokalemia
Question: Hypokalemia is seen with -a) Frusemideb) Cortisolc) Amilorided) Addison's disease
A. ac
B. a
C. ad
D. ab
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Hypokalemia
Question: Hypokalemia in an infant may be due to all of the following except –
A. Adrenal tumor
B. Acute renal failure
C. Thiazide therapy
D. Diarrhea
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Hypokalemia
Question: Hypeension with Hypokalemia is seen in:
A. Bater Syndrome
B. Liddle's Syndrome
C. Gitelman's Syndrome
D. All of the above
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Hypokalemia
Question: Hypokalemia in an infant may be due to all of the following except -
A. Adrenal tumor
B. Adrenal tumor
C. Thiazide therapy
D. Diarrhea
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Hypokalemia
Question: Hypokalemia with hypeension is seen in?
A. Bater syndrome
B. Primary hyperaldosteronism
C. Primary hyperparathyroidism
D. Diuretic therapy
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Hypokalemia
Question: Hypokalemia causes:
A. Increased amplitude of action potential
B. Hyperpolarisation
C. Resting membrane potential becomes less negative
D. Tetany
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Hypokalemia
Question: ECG changes in Hypokalemia are?
A. Tall T wave
B. Poor P wave
C. Sho QT interval
D. Presence of U wave
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Hypokalemia
Question: An adolescent male presents with Hypokalemia, Metabolic Alkalosis, Hypercalciuria and Nephrocalcinosis. His Blood Pressure is normal. The likely diagnosis is:
A. Bater Syndrome
B. Gitelman's Syndrome
C. Liddle's Syndrome
D. Renal Tubular Acidosis
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hypokalemia
Question: Hypokalemia is a characteristic feature of toxicity with:-
A. Barium
B. Antimony
C. Copper
D. Iron
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hypokalemia
Question: Acute complication of PEM – a)  Hypothermiab)  Hypoglycemiac)  Hypokalemiad)  Hypermagnesaemiae)  Eosinophilia
A. ab
B. bc
C. abc
D. bcd
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Hypokalemia
Question: Hypokalemia is seen in therapy with
A. Digitalis
B. Ibuprufen
C. Corticosteroids
D. Diazepam
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hypokalemia
Question: Hypokalemia.may be a feature of all following diseases, except -
A. Addison's disease
B. Cushing's syndrome
C. Baer's syndrome
D. Guelman's syndrome
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hypokalemia
Question: ECG change seen in Hypokalemia
A. Tall 'T' wave
B. U wave
C. Sine wave configration
D. Shoening of QT interval
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Hypokalemia
Question: Hypokalemia may be a feature of all following diseases, except -
A. Addison's disease
B. Cushing's syndrome
C. Barter's syndrome
D. Gitelman's syndrome
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hypokalemia
Question: Hypokalemia with hypertension is associated with following except
A. Liddle's syndrome
B. Conn's syndrome
C. Bartter's syndrome
D. Cushing's syndrome
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Hypokalemia
Question: True about pyloric stenosisa) Hypokalemiab) Hyponatremiac) Metabolic acidosisd) Hypochloremiae) Hypocalcemia
A. abd
B. bcd
C. abc
D. ab
Correct option (0=A, 1=B, 2=C, 3=D): 0
Rare disease: Hypokalemia
Question: Digoxin toxicity is aggravated by: a) Hypokalemia b) Hyperkalernia c) Hypercalcemia d) Hypermagnesemia e) Hypocalcemia
A. ad
B. bc
C. cd
D. ac
Correct option (0=A, 1=B, 2=C, 3=D): 3
Rare disease: Hypokalemia
Question: Hypokalemia is seen in all except?
A. Barter syndrome
B. Hypokalemic periodic paralysis
C. 21 hydroxylase deficiency
D. Reninoma (JG cell tumour)
Correct option (0=A, 1=B, 2=C, 3=D): 2
Rare disease: Hypokalemia
Question: Which of the following represents the earliest ECG changes in a patient with Hypokalemia?
A. Pseudo-P-Pulmonale
B. Flattening of T wave
C. Development of U wave
D. Fusion of TU waves
Correct option (0=A, 1=B, 2=C, 3=D): 1
Rare disease: Hypokalemia