The Universitat Jaume I participates in the design of new biomedical instrumentation through the CONcISE project



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## The Universitat Jaume I participates in the design of new biomedical instrumentation through the CONcISE project

23/07/2024 |
SCP

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Image resource CONcISE \_y5a6627
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Image resource CONcISE \_y5a6599

* [![ CONcISE _y5a6627](/com/investigacio/arxiu/noticies/2024/6/CONcISE/_y5a6627.jpg)](#)
* [![ CONcISE _y5a6599](/com/investigacio/arxiu/noticies/2024/6/CONcISE/_y5a6599.jpg)](#)

In the photo, researchers Heberley Tobón and Samuel Zapata, with one of the new microscopes developed in the project.

The diagnostic imaging equipment and procedures used in healthcare today are the result of scientific advances and interdisciplinary work in physics, mathematics, materials science, electrical engineering, computer science, biochemistry and medicine.

Their use has evolved from the early application of X-rays for fracture diagnosis and foreign body detection to a technology that not only enables better patient care, but also the study of fundamental questions in biomedicine.

The CONcISE project, funded by the Horizon Europe research framework programme and involving the Optics Research Group of the Universitat Jaume I, aims to develop new tools to enhance the information contained in medical images, making them more useful for healthcare professionals, more comfortable for patients and easier for technical staff.

Specifically, the project aims to develop new devices for multidimensional biomedical optical imaging to detect and map light absorption, scattering and fluorescence in biological tissues using visible and near-infrared light. The additional ability to measure these parameters in dimensions not perceived by the human eye, such as time and wavelength, together with space, enhances the diagnostic capabilities of biomedical devices.

Using microdisplays, such as those applied in video projection systems in consumer electronics, the CONcISE network aims to develop new devices that allow images to be compressed during measurement. "This change represents an innovative approach and a step forward in biomedical imaging with more effective and efficient devices," explains the research team.

Surprisingly, the images are captured with a single pixel, as opposed to millions in conventional cameras, allowing innovative detection strategies such as 'compressed sensing' to achieve compression rates of more than 90%, thus reducing the need for massive data storage.

This strategy also allows information invisible to the human eye, such as radiation polarisation, to be incorporated into the image capture, providing rich information for clinical diagnosis.

The consortium, made up of computational, experimental and industrial specialists from different European countries, aims to train eleven new PhD students in this complex and high-potential field by providing advanced, multidisciplinary training covering all aspects of biomedical imaging science: modelling, design, development, data analysis, validation and translation into applications.

The team from the public university of Castellón, led by Professor of Optics Jesús Lancis, also includes researcher Enrique Tajahuerce and PhD students Heberley Tobón and Samuel Zapata, all members of the Optics Group of Castellón, part of the Institute of New Imaging Technologies.

On the one hand, SMART-DOT aims to simultaneously map the absorption and scattering of light at different wavelengths in thick biological tissues in 3D, paving the way for the design of novel imaging systems such as optical mammography and functional brain imaging.

SMART-FLUO is a more clinically oriented system for quantitative endoscopic fluorescence imaging that can be used during surgery guided by exogenous contrast agents.

Finally, SMART-2PM aims to obtain high-resolution images of biological samples using non-linear microscopy to improve the fundamental balance between penetration depth, sensitivity and imaging speed by simultaneously applying adaptive optics and computational imaging strategies.

CONcISE (COmputatioNal Imaging as training Network for Smart biomedical dEvices) is funded by the Marie Skłodowska-Curie Actions (MSCA) of the HE programme and led by the Consiglio Nazionale delle Ricerche of Italy. It brings together eight beneficiaries: Institute of Photonics and Nanotechnologies (IFN)-Italy; University of Eastern Finland (UEF); the Italian SME Datrix; University of Strasbourg (UNISTRA); Politecnico di Milano (POLIMI); UJI; Centrum Wiskunde & Informatica (CWI) from the Netherlands and the company FYLA and four associated partners: University College London (UCL), ViALUX GmbH, Intuitive Surgical and accelopment Schweiz AG (accelCH).

More information: <https://concise-project.eu/>

![](https://ujiapps.uji.es/ade/rest/storage/VUVHC0XHMSAW7AKBS6EREECMWUKLSBAZ)

\*Project funded by the European Union. The views and opinions expressed herein are those of the authors and do not necessarily reflect those of the European Union or the European Health and Digital Executive Agency (HaDEA). Neither the European Union nor the granting authority can be held responsible for them.

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