ghanaopendata/ghanaian-research-english huggingface dataset:
A cross-sectional comparative study of perceived stigma betweenpatients with epilepsy and patients living with HIV/AIDS in Accra, Ghana

Background Health-related stigma is a great challenge to the treatment of diseases. In epilepsy like other conditions, it causes affected individuals to conceal their illness. In this study, we described stigma perceived by patients with epilepsy at the Korle Bu Teaching Hospital (KBTH), a tertiary referral facility, and the Accra Psychiatry Hospital in Ghana (APH). We then compared the perception of stigma in patients with epilepsy to stigma perceived by persons living with human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) (PLWHA), a chronic communicable disease stigmatized in Ghana. Methods A total of 351 patients with epilepsy were recruited from both sites by systematic random sampling and interviewed. The Kilifi Stigma Scale for Epilepsy was used to determine individual patient's stigma score. Statistical analysis was done using multiple logistic regression analysis to control for the effect of measured independent variables that were significant on univariate analysis: age, gender, marital status, income, type of epilepsy, and the frequency of seizures, on the outcome variable. Comparative analysis of the mean stigma score in patients with epilepsy and persons living with HIV/AIDS was done using the Student's t-test and Mann–Whitney U test (Wilcoxon rank sum test). Results The presence of perceived stigma using the Kilifi Stigma Score Estimation was 32.02% (62), 33.33% (49), and 28.88% (54) among respondents from KBTH, APH, and PLWHA respectively. Results from Wilcoxon rank sum test showed that the median stigma score between the three groups was significant; KBTH and APH (p-value; 0.0258), KBTH and PLWHA (p-value; 0.00001), and APH and PLWHA (p-value; 0.0000). Age (< 40 years), seizure frequency, ethnic group (Ewe and Guan), and being divorced showed high odds for perceived stigma among KBTH patients with epilepsy. Having tertiary education led to lower odds for perceived stigma in epilepsy for APH patients with epilepsy. Conclusion This study showed that epilepsy is associated with a high stigma perception. The perceived stigma was greater than stigma in PLWHAs in Accra. Stigma was affected by unemployment, ethnicity (Ewe and Guan), and uncontrolled seizures. Increasing age reduced perceived stigma and the management of patients with epilepsy in a psychiatric facility might have impacted negatively on the perceived stigma.

Source: UG
Cross-sectional predictability of stock returns, evidence from the 19th century Brussels Stock Exchange (1873-1914)

We use pre-World War I Brussels Stock Exchange (BSE) data to investigate the relation between average stock returns and market beta, size, momentum, dividend yield and total risk on the cross-section of stock returns. Based on portfolio sorts and Fama-MacBeth regressions, we find no relationship between market beta, size or total risk and average returns. Momentum is strongly present in the entire data set as well as in subsamples based on size. We also find evidence for a weak value effect as measured by dividend yield. The flat relation between market beta and average return may be due to leverage-constrained investors. © 2013 Elsevier Inc.

Source: UG
Cross-sectional predictability of stock returns, evidence from the 19th century Brussels Stock Exchange (1873–1914)

Abstract We use pre-World War I Brussels Stock Exchange (BSE) data to investigate the relation between average stock returns and market beta, size, momentum, dividend yield and total risk on the cross-section of stock returns. Based on portfolio sorts and Fama–MacBeth regressions, we find no relationship between market beta, size or total risk and average returns. Momentum is strongly present in the entire data set as well as in subsamples based on size. We also find evidence for a weak value effect as measured by dividend yield. The flat relation between market beta and average return may be due to leverage-constrained investors.

Source: UG
A Cross-Sectional Qualitative Study of Barriers to Effective Therapeutic Communication among Nurses and Patients

Effective communication between patients and nurses is cardinal to health care The study seeks to explore barriers to effective therapeutic communication between patients and nurses in randomly selected health facilities in the Kumasi metropolis, Ashanti region, Ghana. The study employed an exploratory study to interview 60 respondents comprising 30 nurses and patients each, using an unstructured interview guide. In addition to nurses' and patients'perceived barriers, the study revealed the health environment–related barriers. Patients-related barriers include individual sociodemographic attributes, patient–nurse relationship, erroneous impression, and language barrier. Other identified nurses-related barriers include human resource challenges, patients' distrust in nurses’ competency, interference from patients’ relations, inadequate knowledge, patient’s dissatisfaction with output, patients’ emotional fluctuations. Health environment– related barriers also include excessive workload, unconducive environment, and environmental changes. Given the relevance of therapeutic communication to health service, the study, among other things recommends that efforts be exerted by sector actors to address the challenges and help promote quality in health-care service and delivery.

Source: UG
Cross-sectional study of association between psychosocial stressors with chronic kidney disease among migrant and non-migrant Ghanaians living in Europe and Ghana: the RODAM study

Objectives The association between psychosocial stressors (PS) and chronic kidney disease (CKD) among sub-Saharan African (SSA) populations is unknown. We examined the association between PS and CKD prevalence among rural and urban Ghanaians and Ghanaian migrants living in three European cities. We also assessed if the influence of PS on CKD is partially mediated by primary risk factors (hypertension and diabetes) of CKD. Design A multi-centred cross sectional data from the Research on Obesity and Diabetes among African Migrants study. Setting Rural and urban Ghana and three European cities (Amsterdam, Berlin and London). Participants A random sample of 5659 adults (Europe 3167, rural Ghana 1043 and urban Ghana 1449) aged 25–70 years. Explanatory measures PS defined by negative life events, perceived discrimination, perceived stress at work/ home and depressive symptoms. Three CKD outcomes were considered using the 2012 Kidney Disease: Improving Global Outcomes severity of CKD classification. Comparisons between PS and CKD outcomes were made using logistic regression analyses across all sites. Results We observed higher proportion of negative life events (68.7%) and perceived permanent stress (15.9%) among Ghanaians living in Ghana than Ghanaians living in Europe. Depressive symptoms (7.5%) and perceived discrimination (29.7%) were more common among Ghanaians living in Europe than Ghanaians living in Ghana. No significant association was observed between any of the PS constructs and CKD outcomes across sites except for positive association between stress at work/home and albuminuria (2.81, 95% CI 1.46 to 5.40) and CKD risk (2.78, 95% CI 1.43 to 5.43) among Ghanaians living in Berlin. Conclusion Our study found a positive association between stress at work/home and albuminuria and CKD risk. There was no convincing evidence of associations between the other PS constructs and the prevalence of CKD risk. Further studies are needed to identify potential factors driving the high prevalence of CKD among these populations.

Source: UG
Cross-sectional study of association between socioeconomic indicators and chronic kidney disease in rural-urban Ghana: The RODAM study

Objectives Studies from high-income countries suggest higher prevalence of chronic kidney disease (CKD) among individuals in low socioeconomic groups. However, some studies from low/middle-income countries show the reverse pattern among those in high socioeconomic groups. It is unknown which pattern applies to individuals living in rural and urban Ghana. We assessed the association between socioeconomic status (SES) indicators and CKD in rural and urban Ghana and to what extent the higher SES of people in urban areas of Ghana could account for differences in CKD between rural and urban populations. Setting The study was conducted in Ghana (Ashanti region). We used baseline data from a multicentre Research on Obesity and Diabetes among African Migrants (RODAM) study. Participants The sample consisted of 2492 adults (Rural Ghana, 1043, Urban Ghana, 1449) aged 25–70 years living in Ghana. Exposure Educational level, occupational level and wealth index. Outcome Three CKD outcomes were considered using the 2012 Kidney Disease: Improving Global Outcomes severity of CKD classification: albuminuria, reduced glomerular filtration rate and high to very high CKD risk based on the combination of these two. Results All three SES indicators were not associated with CKD in both rural and urban Ghana after age and sex adjustment except for rural Ghana where high wealth index was significantly associated with higher odds of reduced estimated glomerular filtration rate (eGFR) (adjusted OR, 2.38; 95% CI 1.03 to 5.47). The higher rate of CKD observed in urban Ghana was not explained by the higher SES of that population. Conclusion SES indicators were not associated with prevalence of CKD except for wealth index and reduced eGFR in rural Ghana. Consequently, the higher SES of urban Ghana did not account for the increased rate of CKD among urban dwellers suggesting the need to identify other factors that may be driving this.

Source: UG
A cross-sectional study of knowledge and awareness of type 2 diabetes mellitus in a student population in Ghana: do demographics and lifestyle make a difference

ABSTRACT Objective: To determine the level of knowledge and awareness of type 2 diabetes among undergraduate students and to investigate demographic and lifestyle variables associated with students’ level of knowledge and awareness. Design: Students from the University of Ghana (n = 726) were administered questionnaires to assess their knowledge and awareness in specific aspects of type 2 diabetes, namely, symptoms, treatment and complications of the illness. Main Outcome Measures: Level of type 2 diabetes knowledge and awareness. Results: Knowledge and awareness were higher for diabetes treatment (than for diabetes symptoms and complications), with females having more knowledge and awareness than males. Significant differences were also found in the level of knowledge and awareness of students based on their discipline of study but not the number of years of study in the university. Also, students who engaged in physical exercise showed a higher level of general knowledge and awareness of type 2 diabetes. Finally, a family history of diabetes resulted in more knowledge and awareness of type 2 diabetes. Conclusions: Education in type 2 diabetes is needed to make individuals more aware of the illness and take preventive measures. The fact that participants’ discipline of study produced differences in diabetes knowledge and awareness, suggests how education can make a difference in creating awareness

Source: UG
A Cross‑Sectional Study of Simulium Damnosum Sensu Lato Breeding Sites And Species Distribution in Sudan Savanna, Mixed Savanna–Forest and Rainforest Regions In Cameroon

The Department of Parasitology conducts research into parasitic diseases of public health importance with the overall goal of reducing their transmission and the heavy disease burden that they impose on affected populations. The Department maintains focus on parasitic diseases in general. These include major diseases such as malaria, and others listed under the Neglected Tropical Diseases (NTD) control initiative such as, lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminthiasis, trypanosomiasis and leishmaniasis.

Source: UG
A cross-sectional study of tuberculosis drug resistance among previously treated patients in a tertiary hospital in Accra, Ghana: public health implications of standardized regimens

Background Mycobacterium tuberculosis drug resistance is a major challenge to the use of standardized regimens for tuberculosis (TB) therapy, especially among previously treated patients. We aimed to investigate the frequency and pattern of drug resistance among previously treated patients with smear-positive pulmonary tuberculosis at the Korle-Bu Teaching Hospital Chest Clinic, Accra. Methods This was a cross-sectional survey of mycobacterial isolates from previously treated patients referred to the Chest Clinic Laboratory between October 2010 and October 2013. The Bactec MGIT 960 system for mycobactrerial culture and drug sensitivity testing (DST) was used for sputum culture of AFB smear-positive patients with relapse, treatment failure, failure of smear conversion, or default. Descriptive statistics were used to summarize patient characteristics, and frequency and patterns of drug resistance. Results A total of 112 isolates were studied out of 155 from previously treated patients. Twenty contaminated (12.9%) and 23 non-viable isolates (14.8%) were excluded. Of the 112 studied isolates, 53 (47.3%) were pan-sensitive to all first-line drugs tested Any resistance (mono and poly resistance) to isoniazid was found in 44 isolates (39.3%) and any resistance to streptomycin in 43 (38.4%). Thirty-one (27.7%) were MDR-TB. Eleven (35.5%) out of 31 MDR-TB isolates were pre-XDR. MDR-TB isolates were more likely than non-MDR isolates to have streptomycin and ethambutol resistance. Conclusions The main findings of this study were the high prevalence of MDR-TB and streptomycin resistance among previously treated TB patients, as well as a high prevalence of pre-XDR-TB among the MDR-TB patients, which suggest that first-line and second-line DST is essential to aid the design of effective regimens for these groups of patients in Ghana.

Source: UG
A cross-sectional study on coping strategies of frontline healthcare workers amid the COVID-19 pandemic in a developing country

Objectives: Frontline healthcare workers encountered a heightened susceptibility to negative psychological symptoms and behavioral shifts in light of the coronavirus disease 2019 pandemic. This study determined the coping strategies adopted by frontline healthcare workers in Ghana as well as assessed any differences based on demographics, job title, and ranking in four coronavirus disease 2019-designated centers in the Greater Accra region of Ghana. Methods: Using a hospital-based, mixed-method approach, the study was conducted between May 2021 and September 2021. A total of 94 frontline healthcare workers were randomly sampled and given a self-administered questionnaire, while 13 healthcare workers took in-depth interviews. Data from the survey were analyzed using both IBM SPSS and IBM AMOS and the interview data were transcribed verbatim and coded using thematic analysis. Results: The study revealed that coronavirus disease 2019 has affected the psycho-social life of frontline healthcare workers mainly in the form of depression, anxiety, and stress. The three main coping strategies adopted by frontline healthcare workers include personal preventative measures (most dominant), seeking external expert support, and obtaining institutional support. While healthcare workers within the age group 30–39years were found most compliant with the adoption of personal preventive measures and those below 30years were found least compliant. Conclusion: This study concludes that frontline healthcare workers have been affected by a considerable level of anxiety, stress, and depression during the coronavirus disease 2019 pandemic. The study recommends a robust psychological support system at various levels of health care and an Employee Assistance Program with access to a 24-h hotline counseling service for frontline healthcare workers, continuous personal protective equipment provision, regular evidence-based updates on the management of coronavirus disease 2019 patients, and increased commitment from the government in addressing the medical needs of infected frontline healthcare workers

Source: UG
A cross‑sectional study on the nutritional status, dietary diversity, and small fsh consumption patterns in coastal fshing communities of Ghana

Fish is readily available to fshing communities. Given the high nutritional value of fsh, these communities are expected to have better nutritional status, compared to non-fshing communities. However, this assumption is not well studied across coastal fshing communities in Ghana. Hence, this cross-sectional study was conducted to investigate the nutritional status, dietary patterns, and fsh consumption of children living in coastal fshing communities in Ghana. Nutritional status of 384 randomly selected children was assessed using the mid-upper arm circumference (MUAC) measurement. MUAC less than 12.5 cm was used as the cutof to identify malnourished children. Food and fsh consumption patterns were assessed using an adopted and pretested food frequency questionnaire. The fndings showed a prevalence of 0.5% wasting among surveyed children. The mean dietary diversity score (DDS) of the study participants was 4.3 ± 1.2. The mean DDS of the children of fsher mothers was less than that of the children of the female caregivers who are involved in other occupations. However, no signifcant diference was observed in the DDS across the coastal regions. Seventy eight percent of the children who participated in the study consumed an adequately diversifed diet, and more than 40 diferent small fsh species were con sumed across the four coastal regions. The average median weekly fsh intake among the children in the study sample was 213 (64–468) g. Considering that one-third of the employed respondents were fsherfolk, coupled with the availability of a great diversity of small fsh in the communities, the fndings of our study suggest that there is great potential to incorporate small fsh into strategic interventions aimed at improving nutrition, food security, and achieving economic sustainability in these communities.

Source: UG
A cross-sectional survey on patient safety culture among healthcare providers in the Upper East region of Ghana

Introduction Adverse events pose a serious threat to quality patient care. Promoting a culture of safety is essential for reducing adverse events. This study aims to assess healthcare providers’ perceptions of patient safety culture in three selected hospitals in the Upper East region of Ghana. Methods The English version of the Hospital Survey on Patient Safety Culture (HSOPSC) questionnaire was administered to 406 clinical staff. Statistical Package for Social Science (SPSS) software, version 23, was used to analyze the data. The results were presented using descriptive statistics, Pearson Correlation Analysis and One-way Analysis of Variance (ANOVA). Results It was found that two out of twelve patient safety culture dimensions recorded high positive response rates (� 70%). These include teamwork within units (81.5%) and organizational learning (73.1%). Three patient safety culture dimensions (i.e. staffing, non-punitive response to error and frequency of events reported) recorded low positive response rates (� 50%). The overall perception of patient safety correlated significantly with all patient safety culture dimensions, except staffing. There was no statistically significant difference in the overall perception of patient safety among the three hospitals. Conclusion Generally, healthcare providers in this study perceived patient safety culture in their units as quite good. Some of the respondents perceived punitive response to errors. Going forward, healthcare policy-makers and managers should make patient safety culture a top priority. The managers should consider creating a ‘blame-free’ environment to promote adverse event reporting in the hospitals

Source: UG
Crossing conceptual boundaries: re-envisioning coordination and collaboration among women for sustainable livelihoods in Ghana

This paper explores the complexities, degree of organisation and embedded potentials in selected informal worlds of work involving women in Agbogbloshie, a site that has achieved both national and international notoriety for its ostensible environmental and social unrest challenges. The analysis provides empirical evidence to show how informality remains a persistent, substantial and the defining feature of Ghana’s economy in terms of its fostering growth and creating jobs, although its overall role in the national development discourse is largely ignored or seldom considered. Drawing on participant observation and qualitative field-based survey data, the paper presents the multi-dimensional ways migrant women from northern Ghana adopt to innovate, network and “graduate” from e-waste-related activities to engage in long-distance trade, which, in turn, serves as a catalyst for spin-off activities that manifest differently between the south and the north of the country. It also sheds light on how these women, with little prospect of formal employment, negotiate contemporary economic shifts and create an occupational continuum that defies strict compartmentalisation. The paper adds to the expanding corpus of writings on informalisation as a growing, noteworthy and integral feature of Sub-Saharan Africa’s economy.

Source: UG
Croton membranaceus Improves Some Biomarkers of Cardiovascular Disease and Diabetes in Genetic Animal Models

Cardiovascular disease (CVD) accounts for 17.3 million deaths per year globally. In Ghana, CVD accounts for 22.2% of deaths. Croton membranaceus (CM) Mull. Arg. (Euphorbiaceae), a medicinal plant in Ghana is mainly used traditionally for the treatment of benign prostatic hyperplasia and measles. However, some hypoglycaemic and hypotensive effects have recently been reported but not scientifically examined. The study aimed at establishing whether Croton membranaceus (CM) used for prostatitis had any effect on CVD markers. In experiment 1, lipid profile changes were determined. Twenty four male Spontaneously Hypertensive Rats (SHR) were divided into 4 groups. Low (LD), intermediate (ID) and high dose (HD) groups received 25, 50 and 100 mg/kg b.wt. CM aqueous root extracts (CMARE) for 60 days, respectively, the controls received distilled water. In experiment 2, blood glucose levels (BGL) were determined. 21 db/db mice were divided into 3 groups of 7 mice each alongside db/+ mice (7) (negative control). Groups 1 and 2 received 250 mg/kg b.wt CMARE and metformin, respectively. Group 3 (positive control) and db/+ mice (negative control) received distilled water. Mice were monitored for 15 hours. Data collected were analysed using SPSS version 20. Hypotriglyceridaemic effect was observed (p=0.005). High Density Lipoprotein cholesterol (HDL) and Low Density Lipoprotein cholesterol (LDL) showed significant increases (p=0.013) and decreases (p=0.003), respectively. A significant CRP reduction was observed for ID and HD groups (p = 0.010, p = 0.011, respectively). BGL was reduced in Metformin and Croton groups (p=0.000; p= 0.006, respectively) after 3 hours. In conclusion, CMARE has positive effects on some CVD biomarkers and a hypoglycaemic effect.

Source: UG