ghanaopendata/ghanaian-research-english huggingface dataset:
Global occurrence of anti-infectives in contaminated surface waters: Impact of income inequality between countries

The presence anti-infectives in environmental waters is of interest because of their potential role in the dissemination of anti-infective resistance in bacteria and other harmful effects on non-target species such as algae and shellfish. Since no information on global trends regarding the contamination caused by these bioactive substances is yet available, we decided to investigate the impact of income inequality between countries on the occurrence of anti-infectives in surface waters. In order to perform such study, we gathered concentration values reported in the peer-reviewed literature between 1998 and 2014 and built a database. To fill the gap of knowledge on occurrence of anti-infectives in African countries, we also collected 61 surface water samples from Ghana, Kenya, Mozambique and South Africa, and measured concentrations of 19 anti-infectives. A mixed one-way analysis of covariance (ANCOVA) model, followed by Turkey-Kramer post hoc tests was used to identify potential differences in anti-infective occurrence between countries grouped by income level (high, upper-middle and lower-middle and low income) according to the classification by the World Bank. Comparison of occurrence of anti-infectives according to income level revealed that concentrations of these substances in contaminated surface waters were significantly higher in low and lower-middle income countries (p=0.0001) but not in upper-middle income countries (p=0.0515) compared to high-income countries. We explained these results as the consequence of the absence of or limited sewage treatment performed in lower income countries. Furthermore, comparison of concentrations of low cost anti-infectives (sulfonamides and trimethoprim) and the more expensive macrolides between income groups suggest that the cost of these substances may have an impact on their environmental occurrence in lower income countries. Since wastewaters are the most important source of contamination of anti-infectives and other contaminants of emerging concern in the environment, it is expected that deleterious effects to the aquatic biota caused by these substances will be more pronounced in countries with inadequate wastewater and collection infrastructure. With the information currently available, we could not evaluate either the role of the receiving environment or the importance of regulatory frameworks on the occurrence of anti-infectives in surface waters. Future studies should focus on these two factors in order to better evaluate risks to aquatic ecosystems in LM&LICs. We propose that CECs such as anti-infectives could be used as a new class of environmental degradation indicators that could be helpful to assess the state of development of wastewater collection and treatment infrastructure around the world.

Source: UG
Global Perspective on Marital Satisfaction

Across the world, millions of couples get married each year. One of the strongest predictors of whether partners will remain in their relationship is their reported satisfaction. Marital satisfaction is commonly found to be a key predictor of both individual and relational well-being. Despite its importance in predicting relationship longevity, there are relatively few empirical research studies examining predictors of marital satisfaction outside of a Western context. To address this gap in the literature and complete the existing knowledge about global predictors of marital satisfaction, we used an open-access database of self-reported assessments of self-reported marital satisfaction with data from 7178 participants representing 33 different countries. The results showed that sex, age, religiosity, economic status, education, and cultural values were related, to various extents, to marital satisfaction across cultures. However, marriage duration, number of children, and gross domestic product (GDP) were not found to be predictors of marital satisfaction for countries represented in this sample. While 96% of the variance of marital satisfaction was attributed to individual factors, only 4% was associated with countries. Together, the results show that individual differences have a larger influence on marital satisfaction compared to the country of origin. Findings are discussed in terms of the advantages of conducting studies on large cross-cultural samples.

Source: UG
The global prevalence and correlates of skin bleaching: a meta-analysis and meta-regression analysis

PURPOSE: To estimate and investigate the global lifetime prevalence and correlates of skin bleaching. METHODS: A meta-analysis and meta-regression analysis was performed based on a systematic and comprehensive literature search conducted in Google Scholar, ISI Web of Science, ProQuest, PsycNET, PubMed, and other relevant websites and reference lists. A total of 68 studies (67,665 participants) providing original data on the lifetime prevalence of skin bleaching were included. Publication bias was corrected using the trim and fill procedure. RESULTS: The pooled (imputed) lifetime prevalence of skin bleaching was 27.7% (95% CI: 19.6-37.5, I2 = 99.6, P < 0.01). The highest significant prevalences were associated with: males (28.0%), topical corticosteroid use (51.8%), Africa (27.1%), persons aged ≤30 years (55.9%), individuals with only primary school education (31.6%), urban or semiurban residents (74.9%), patients (21.3%), data from 2010-2017 (26.8%), dermatological evaluation and testing-based assessment (24.9%), random sampling methods (29.2%), and moderate quality studies (32.3%). The proportion of females in study samples was significantly related to skin bleaching prevalence. CONCLUSION: Despite some limitations, our results indicate that the practice of skin bleaching is a serious global public health issue that should be addressed through appropriate public health interventions.

Source: UG
Global public health starts at home: upstream approaches to global health training

The interconnectedness of today's globalised world brings with it challenges and inequality in the health of populations. But all too often health professionals' training focuses on downstream individual intervention approaches (eg, smoking cessation, diet improvement), at the expense of upstream determinants (eg, food marketing, trade agreements). A crop of global health degrees has emerged aimed at explaining and understanding diseases of global importance. However, these courses are largely taught from a position of assumed power in which those from the wealthy nations have greater leverage than their counterparts from low-income and middle-income countries (LMICs). We set out to challenge the philosophies and approaches for action that are taught in global health training courses, which have been slow to tackle more foundational issues. Highlighting trade agreements and the political economy of health as examples, we stress the need for a greater emphasis on intervening in the upstream social, economic, and commercial determinants of health. Although we recognise that the terms “global north” and “global south” are an oversimplification of the global distribution of power and resources that do not comprehensively capture the heterogeneity of the global south, we merely use these terms to scaffold discussion on power asymmetries and dynamics that influence health.

Source: UG
Global research priorities on COVID-19 for maternal, newborn, child and adolescent health

Background This research prioritization aimed to identify major research gaps in maternal, newborn, child, and adolescent health (MNCAH) to help mitigate the direct and indirect effects of the COVID-19 pandemic. Methods We adapted the Child Health and Nutrition Research Initiative methodology. We defined scope, domains, themes, and scoring criteria. We approached diverse global experts via email to submit their research ideas in MNCAH and MNCAH-related cross-cutting/ health systems area. We curated the research ideas as research questions (RQs) and sent them to the consenting experts for scoring via the online link. For each RQ, the research priority score (RPS) was calculated as an average of individual criterion scores and ranked based on RPS in each area. Results We identified the top-ranked 10 RQs in each maternal, newborn, and child and adolescent health and 5 in the cross-cutting/health systems area. In maternal health, indirect effects on care, measures to improve care, health risks and outcomes, and preventing and managing SARS-CoV-2 infection/COVID-19 disease were priority RQs. In newborn health, clinical characterization and managing SARS-CoV-2 infection/COVID-19 disease, mode of transmission, and interventions to prevent transmission were the focus. For child and adolescent health, top-ranked RQs were indirect effects on care, clinical status, and outcomes, interventions to protect against SARS-CoV-2 infection/COVID-19 disease, and educational institute-related RQs. The cross-cutting RQs were the effects of the pandemic on the availability, access, care-seeking, and utilization of MNCAH services and potential solutions. Conclusions We call on partners, including governments, non-governmental organizations, research institutes, and donors, to address this urgent research agenda.

Source: UG
Global resource grabs, agribusiness concentration and the smallholder: Two West African case studies

This paper places land grabbing within the context of developments within agribusiness within the last 30 years, tracing the various trajectories of increasing competition and concentration and pressures on commodity prices that have resulted in increasing dispossession of smallholders and a move in some agri-food chains towards large estate production. The paper explores the ways in which contemporary agricultural policies and neoliberal market reforms reflect these developments and examines recent framing of land policies in Africa in the context of the development of agrarian capital and agribusiness. Competitiveness results in dispossession of less successful smallholders from below by commercial smallholders, and from above by large estates vertically integrated into agribusiness marketing chains. This is illustrated with examples from the cocoa sector in Côte d'Ivoire and pineapples in Ghana. © 2012 Copyright Taylor and Francis Group, LLC.

Source: UG
Global Role and Burden of Influenza in Pediatric Respiratory Hospitalizations, 1982–2012: A Systematic Analysis

Most research activities involve the use of molecular methods such as regular PCR (PCR), quantitative PCR (Q-PCR), genomic sequence and analysis using different software, genetic engineering, probe hybridization techniques, biological and molecular cloning, evaluation of immune markers for laboratory diagnosis of infections, serological assays involving the use of rapid tests, ELISA-based evaluations and immunofluorescent assay techniques.

Source: UG
Global sharing of COVID-19 therapies during a “New Normal”

This paper argues for global sharing of COVID‐19 treatments during the COVID‐19pandemic and beyond based on principles of global solidarity. It starts by distinguishing two types of COVID‐19 treatments and models sharing strategies for each in small‐group scenarios, contrasting groups that are solidaristic with those composed of self‐interest maximizers to show the appeal of solidaristic reasoning. It then extends the analysis,arguing that a similar logic should apply within and between nations. To further elaborate global solidarity, the paper distinguishes morally voluntary, sliding‐scale, and mandatory versions. It argues for an all‐hands‐on‐deck approach and gives examples to illustrate. The paper concludes that during the COVID‐19 crisis, global solidarity is a core value, and global sharing of COVID‐19 treatments should be considered a duty of justice, not of charity.

Source: UG
Global Social Welfare and Social Policy Debates: Ghana’s Health Insurance Scheme Promotion of the Well-Being of Vulnerable Groups

This article analyses social welfare, social policy with individualist and collectivist theoretical perspectives. It discusses the well-being of vulnerable groups and their access to social services including healthcare in the implementation of the National Health Insurance Scheme (NHIS) in Ghana. The aim is to find out the extent of vulnerable groups enrollment and if their welfare and well-being have improved in the implementation of Ghana’s health insurance scheme. Also, it examines whether NHIS is a pro-poor social intervention program or not. Data sources include census data, documents from health insurance authority, in-depth interviews, focus group discussions, direct observations at social service delivery points. Purposive, cluster and snowball sampling techniques are used to select participants. The sample size is 107 participants with 12 months of intensive data collection in three phases from 2012, 2013 and ended on October 2014. Results show more vulnerable groups are enrolled in NHIS compared with contributors. This suggests people who do not pay annual premiums constituted most health insurance subscribers. Also, the results show health insurance covered 38% of Ghana’s population for the 10 years of implementation of NHIS (2004–2013). Despite the progressive increase in coverage of NHIS, there are still some implementation challenges. The research found certain behaviors, practices, and attitudes of some social service providers as inhibiting subscribers’ enrollment. Future research may focus on social intervention programs for vulnerable groups across states.Health insurance scheme

Source: UG
Global Sourcing of Low‑Inorganic Arsenic Rice Grain

Arsenic in rice grain is dominated by two species: the carcinogen inorganic arsenic (the sum of arsenate and arsenite) and dimethylarsinic acid (DMA). Rice is the dominant source of inorganic arsenic into the human diet. As such, there is a need to identify sources of low-inorganic arsenic rice globally. Here we surveyed polished (white) rice across representative regions of rice production globally for arsenic speciation. In total 1180 samples were analysed from 29 distinct sampling zones, across 6 continents. For inorganic arsenic the global ̃x was 66 μg/kg, and for DMA this figure was 21 μg/kg. DMA was more variable, ranging from < 2 to 690 μg/kg, while inorganic arsenic ranged from < 2 to 399 μg/kg. It was found that inorganic arsenic dominated when grain sum of species was < 100 μg/kg, with DMA dominating at higher concentrations. There was considerable regional variance in grain arsenic speciation, particularly in DMA where temperate production regions had higher concentrations. Inorganic arsenic concentrations were relatively consistent across temperate, subtropical and northern hemisphere tropical regions. It was only in southern hemisphere tropical regions, in the eastern hemisphere that low-grain inorganic arsenic is found, namely East Africa ( ̃x < 10 μg/kg) and the Southern Indonesian islands ( ̃x < 20 μg/kg). Southern hemisphere South American rice was universally high in inorganic arsenic, the reason for which needs further exploration.

Source: UG
The Global Spread of Rotavirus G10 Strains: Detection in Ghanaian Children Hospitalized with Diarrhea

The main research focus of the Electron Microscopy and Histopathology Department in the past 20 years has been in the areas of enteric diarrhoeas with special emphasis on rotavirus. Through its diarrhoea surveillance studies, the Department has helped to firmly establish rotaviruses as a major cause of diarrhoea in children, and document the circulation of unusual rotavirus genotypes in Ghana. The Department has also recently expanded its diagnostic repertoire to include the identification and characterization of noroviruses, astroviruses, and other enteric viruses.

Source: UG
Global Stein Theorem on Hardy Spaces

Let f be an integrable function which has integral 0 on ℝn. What is the largest condition on ❘ f ❘ that guarantees that f is in the Hardy space H1 (ℝn)? When f is compactly supported, it is well-known that the largest condition on ❘f❘ is the fact that ❘f❘ ∈ L log L(ℝn). We consider the same kind of problem here, but without any condition on the support. We do so for H1 (ℝn), as well as for the Hardy space Hlog (ℝn) which appears in the study of pointwise products of functions in H1 (ℝn) and in its dual BMO.

Source: UG
Global Study of Social Odor Awareness

Olfaction plays an important role in human social communication, including multiple domains in which people often rely on their sense of smell in the social context. The importance of the sense of smell and its role can however vary inter-individually and culturally. Despite the growing body of literature on differences in olfactory performance or hedonic preferences across the globe, the aspects of a given culture as well as culturally universal individual differences affecting odor awareness in human social life remain unknown. Here, we conducted a large-scale analysis of data collected from 10,794 participants from 52 study sites from 44 countries all over the world. The aim of our research was to explore the potential individual and country-level correlates of odor awareness in the social context. The results show that the individual characteristics were more strongly related than country-level factors to self-reported odor awareness in different social contexts. A model including individual-level predictors (gender, age, material situation, education and preferred social distance) provided a relatively good fit to the data, but adding country-level predictors (Human Development Index, population density and average temperature) did not improve model parameters. Although there were some cross-cultural differences in social odor awareness, the main differentiating role was played by the individual differences. This suggests that people living in different cultures and different climate conditions may still share some similar patterns of odor awareness if they share other individual-level characteristics.

Source: UG
A Global Survey of Hypervirulent Aeromonas hydrophila (vAh) Identified vAh Strains in the Lower Mekong River Basin and Diverse Opportunistic Pathogens from Farmed Fish and Other Environmental Sources

Hypervirulent Aeromonas hydrophila (vAh) has emerged as the etiologic agent of epidemic outbreaks of motile Aeromonas septicemia (MAS) in high-density aquaculture of farmed carp in China and catfish in the United States, which has caused millions of tons of lost fish. We conducted a global survey to better understand the evolution, geographical distribution, and phylogeny of vAh. Aeromonas isolates were isolated from fish that showed clinical symptoms of MAS, and pure cultures were screened for the ability to utilize myoinositol as the sole carbon source. A total of 113 myo-inositol-utilizing bacterial strains were included in this study, including additional strains obtained from previously published culture collections. Based on a gyrB phylogeny, this collection included 66 A. hydrophila isolates, 48 of which were vAh. This collection also included five new vAh isolates from diseased Pangas catfish (Pangasius pangasius) and striped catfish (Pangasianodon hypophthalmus) obtained in Cambodia and Vietnam, respectively. Genome sequences were generated from representative vAh and non-vAh isolates to evaluate the potential for lateral genetic transfer of the myo-inositol catabolism pathway. Phylogenetic analyses of each of the nine genes required for myo-inositol utilization revealed the close affiliation of vAh strains regardless of geographic origin and suggested lateral genetic transfer of this catabolic pathway from an Enterobacter species. Prediction of virulence factors was conducted to determine differences between vAh and non-vAh strains in terms of virulence and secretion systems. Core genome phylogenetic analyses on vAh isolates and Aeromonas spp. disease isolates (55 in total) were conducted to evaluate the evolutionary relationships among vAh and other Aeromonas sp. isolates, which supported the clonal nature of vAh isolates.

Source: UG
Global survey shows planners use widely varying sea-level rise projections for coastal adaptation

Including sea-level rise (SLR) projections in planning and implementing coastal adaptation is crucial. Here we analyze the first global survey on the use of SLR projections for 2050 and 2100. Two-hundred and fifty-three coastal practitioners engaged in adaptation/planning from 49 countries provided complete answers to the survey which was distributed in nine languages – Arabic, Chinese, English, French, Hebrew, Japanese, Korean, Portuguese and Spanish. While recognition of the threat of SLR is almost universal, only 72% of respondents currently utilize SLR projections. Generally, developing countries have lower levels of utilization. There is no global standard in the use of SLR projections: for locations using a standard data structure, 53% are planning using a single projection, while the remainder are using multiple projections, with 13% considering a low-probability high-end scenario. Countries with histories of adaptation and consistent national support show greater assimilation of SLR projections into adaptation decisions. This research provides new insights about current planning practices and can inform important ongoing efforts on the application of the science that is essential to the promotion of effective adaptation.

Source: UG
Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

The Department of Parasitology conducts research into parasitic diseases of public health importance with the overall goal of reducing their transmission and the heavy disease burden that they impose on affected populations. The Department maintains focus on parasitic diseases in general. These include major diseases such as malaria, and others listed under the Neglected Tropical Diseases (NTD) control initiative such as, lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminthiasis, trypanosomiasis and leishmaniasis.

Source: UG