gebhart/patrepeval huggingface dataset:
Design and Implementation of Double-Key based Light Weight Security Protocol in Ubiquitous Sensor Network (2007)

유비쿼터스 컴퓨팅은 사용자에게 장소와 시간에 제약이 없이 자유롭게 네트워크에 접속 할 수 있는 환경을 제공하고 있다. 이러한 환경은 모든 정보의 공유 및 접근이 쉽게 이루어지는 반면, 인가되지 않은 사용자의 불법적인 접근도 쉽게 이루어질 수 있기 때문에 적합한 보안 정책이 필요하다. 특히 유비쿼터스 센서 네트워크의 센서 노드들은 제한된 전력을 이용하고 하드웨어적으로 작은 크기를 유지해야 하기 때문에 보안 정책 수립에 많은 제한이 발생하게 된다. 본 논문에서는 유비쿼터스 센서 네트워크에서 센서의 운영체제와 플랫폼, 라우팅 방식에 종속적이지 않은 더블키를 이용한 경량 보안 프로토콜을 제안한다. 본 논문에서는 더블키 방식을 제안하여 인증과 안전한 키 분배 및 교체가 이루어 질 수 있도록 한다. 보안 관리자가 네트워크 상황에 맞는 보안 레벨 변경 및 키 교체, 관리가 가능하기 때문에 적은 연산 처리만으로 최대의 보안 효과를 얻을 수 있는 장점이 있다. 성능 평가 결과 제안한 유비쿼터스 센서 네트워크에서 더블키를 이용한 경량 보안 프로토콜은 기존의 보안 정책 보다 상대적으로 저전력으로 보안 정책을 활용 할 수 있었다. 제안한 더블키를 이용한 경량 보안 프로토콜은 스마트 오피스 및 스마트 홈과 같은 실제 환경의 유비쿼터스 센서 네트워크에 적합하다고 할 수 있다. Ubiquitous computing supports environment to freely connect to network without restrictions of place and time. This environment enables easy access and sharing of information, but because of easy unauthorized accesses, specified security policy is needed. Especially, ubiquitous sensor network devices use limited power and are small in size, so, many restrictions on policies are bound to happen. This paper proposes double-key based light weight security protocol, independent to specific sensor OS, platform and routing protocol in ubiquitous sensor network. The proposed protocol supports safe symmetric key distribution, and allows security manager to change and manage security levels and keys. This had a strong merit by which small process can make large security measures. In the performance evaluation, the proposed light weight security protocol using double-key in ubiquitous sensor network allows relatively efficient low power security policy. It will be efficient to ubiquitous sensor network, such as smart of ace and smart home.
LiveSync: Deformed Viewing Spheres for Knowledge-Based Navigation (2007)

Although real-time interactive volume rendering is available even for very large data sets, this visualization method is used quite rarely in the clinical practice. We suspect this is because it is very complicated and time consuming to adjust the parameters to achieve meaningful results. The clinician has to take care of the appropriate viewpoint, zooming, transfer function setup, clipping planes and other parameters. Because of this, most often only 2D slices of the data set are examined. Our work introduces LiveSync, a new concept to synchronize 2D slice views and volumetric views of medical data sets. Through intuitive picking actions on the slice, the users define the anatomical structures they are interested in. The 3D volumetric view is updated automatically with the goal that the users are provided with expressive result images. To achieve this live synchronization we use a minimal set of derived information without the need for segmented data sets or data-specific pre-computations. The components we consider are the picked point, slice view zoom, patient orientation, viewpoint history, local object shape and visibility. We introduce deformed viewing spheres which encode the viewpoint quality for the components. A combination of these deformed viewing spheres is used to estimate a good viewpoint. Our system provides the physician with synchronized views which help to gain deeper insight into the medical data with minimal user interaction.
[Effects of tobramycin dexamethasone eye ointment for blepharitis: multi-center clinical trial]. (2013)

The tobramycin dexamethasone eye ointment can improve signs and symptoms of blepharitis patients. Some patients have to face with the risk of elevated intraocular pressure and it's necessary to monitor the intraocular pressure.
General and Highly Efficient Syntheses of <i>m</i>-Fluoro Arenes Using Potassium Fluoride-Exchange Method (1990)

Abstract Tetraphenylphosphonium bromide was found to be a suitable catalyst for the reaction of m-nitroaryl derivatives carrying cyano, nitro, chlorocarbonyl, trifluoromethyl, and chlorosulfonyl groups with potassium fluoride in the presence of a stoichiometric amount of phthaloyl dichloride, giving the corresponding m-fluoro aromatic derivatives in good yields. The catalyst was also found to be efficient for the fluorodesulfonylation of m-(fluorosulfonyl)aryl derivatives to afford m-fluoro arenes by the use of a reaction-distillation technique.
Fluoride glass preforms prepared by a rotational casting process (1982)

A new approach has been developed to fabricate fluoride-glass-cladded fibres from preforms having controlled core/clad ratios and uniform cladding thicknesses. In contrast to earlier casting methods, preform core/clad ratios remained unchanged over the entire length of all preforms. The new method also permits fabrication of much larger preforms.
Neuere Methoden der präparativen organischen Chemie II. 7. Alkylierung aromatischer Amine (1957)

Abstract Mit Hilfe katalytischer Mengen von Aluminium, das sich in aromatischen Aminen unter Amid‐Bildung löst, gelingt es, Olefine bei erhöhter Temperatur in aromatische Amine als Alkyl‐Gruppen in O ‐Stellung zur Amino‐Gruppe einzuführen. Damit ist eine neue präparative Methode zur Herstellung der sonst schwer zugänglichen O ‐alkyl‐substituierten aromatischen Amine gegeben. Die Reaktion läßt sich durch Aluminiumchlorid oder andere Friedel‐Crafts‐Katalysatoren noch aktivieren. Dagegen erhält man mit katalytischen Mengen von Amiden der Alkali‐ und Erdalkalimetalle und Olefinen nur am Stickstoff substituierte Amine.
Asymmetric Synthesis of Bryostatin 2 (1998)

The potent bryostatin antitumor agents are currently in phase II clinical trials for the treatment of a variety of forms of cancer. Aldol reactions and directed reductions are among the essential steps for the formation of fragments A–C in the total synthesis of the title compound. Coupling of these fragments by sulfone-based olefination and alkylation reactions was followed by macrocyclization and introduction of the enoate moieties on rings B and C.
Immunocytochemical studies of cell differentiation during rat salivary gland development (1996)

The development of the rat submandibular and parotid glands has been studied using antibodies to secretory proteins as cell-specific markers. Although the morphology of the glands and the timing of the main steps of cytodifferentiation are substantially different, they have several proteins and developmental features in common. The latter include the initial formation of perinatal acini which undergo a transition to adult acini expressing a different complement of secretory proteins; the development of adult intercalated ducts (ID) from the perinatal acinar cells; and the retention of the perinatal phenotype in some cells of the ID.
The Effects of 2 μG and 4 μG Doses of Dexmedetomidine in Combination with Intrathecal Hyperbaric Bupivacaine on Spinal Anesthesia and its Postoperative Analgesic Characteristics (2014)

Two different doses of dexmedetomidine, an α2-adrenoceptor agonist with analgesic effects, resulted in an increased duration of analgesia and efficacy, decreased postoperative analgesic use and was associated with no notable adverse effects.
Lung irradiation induces pulmonary vascular remodelling resembling pulmonary arterial hypertension (2011)

The findings indicate that partial lung irradiation induces pulmonary vascular remodelling resulting from acute pulmonary endothelial cell loss and consequential pulmonary hypertension. Moreover, the close resemblance of the observed vascular remodelling with vascular lesions in PAH makes partial lung irradiation a promising new model for studying PAH.
Dietary Inclusion of Wheat Bran Arabinoxylooligosaccharides Induces Beneficial Nutritional Effects in Chickens (2008)

ABSTRACT In vivo experiments were conducted to verify whether arabinoxylooligosaccharides (AXOS) obtained as low molecular mass compounds by enzymic hydrolysis from wheat bran arabinoxylan (AX) can exert nutritional effects. Two feeding trials were performed on chickens fed diets with either wheat or maize as the main component. Supplementation of bran AXOS at either 0.5% (w/w) to the wheat‐based diet or at 0.25% (w/w) to the maize‐based diet diets significantly ( P < 0.05) improved the feed conversion rate without increasing the body weight of the animals, thus pointing to improved nutrient utilization efficiency. The positive effect of bran AXOS supplementation on feed utilization efficiency was similar to that obtained by adding an AX‐degrading xylanase directly to the wheat‐based diet. No significant effect on feed utilization efficiency was obtained with another type of nondigestible oligosaccharide such as fructooligosaccharides (FOS) derived from chicory roots. Bran AXOS significantly increased the level of bifidobacteria but not total bacteria in the caeca of the chickens, an effect not observed with either xylanase or FOS addition. These data suggest that bran AXOS have beneficial nutritional effects and may act as prebiotics.
Expression of the Resistance-Nodulation-Cell Division Pump AdeIJK in Acinetobacter baumannii Is Regulated by AdeN, a TetR-Type Regulator (2012)

Resistance-nodulation-division efflux system AdeIJK contributes to intrinsic resistance to various drug classes in Acinetobacter baumannii. By whole-genome sequencing, we have identified in clinical isolate BM4587 the adeN gene, located 813 kbp upstream from adeIJK, which encodes a TetR transcriptional regulator. In one-step mutant BM4666 overexpressing adeIJK, the deletion of cytosine 582 (C(582)) in the 3' portion of this gene was responsible for a frameshift mutation resulting in the deletion of the seven C-terminal residues. trans-Complementation of this BM4587 derivative with a plasmid expressing adeN restored antibiotic susceptibility to the host associated with the loss of adeJ overexpression. The inactivation of adeN in BM4587 led to a diminished susceptibility to antibiotics that are substrates for AdeIJK and to a 5-fold increase in adeJ expression. Taken together, these results indicate that AdeN represses AdeIJK expression. Quantitative reverse transcription-PCR (qRT-PCR) demonstrated that AdeN is constitutively expressed in BM4587 and does not regulate its own expression. Deletion of cytosine 582 and a 394-bp deletion of the 3' part of adeN were found in independent one-step adeIJK-overexpressing mutants selected from clinical isolates BM4667 and BM4651, respectively. The corresponding alterations were located in the α9 helix, which is known to be involved in dimerization, a process essential for the activity of TetR regulators. The adeN gene was detected in all of the 30 A. baumannii strains tested and in Acinetobacter calcoaceticus, Acinetobacter nosocomialis, and Acinetobacter pittii.
Novel non-specific DNA adenine methyltransferases (2011)

The mom gene of bacteriophage Mu encodes an enzyme that converts adenine to N(6)-(1-acetamido)-adenine in the phage DNA and thereby protects the viral genome from cleavage by a wide variety of restriction endonucleases. Mu-like prophage sequences present in Haemophilus influenzae Rd (FluMu), Neisseria meningitidis type A strain Z2491 (Pnme1) and H. influenzae biotype aegyptius ATCC 11116 do not possess a Mom-encoding gene. Instead, at the position occupied by mom in Mu they carry an unrelated gene that encodes a protein with homology to DNA adenine N(6)-methyltransferases (hin1523, nma1821, hia5, respectively). Products of the hin1523, hia5 and nma1821 genes modify adenine residues to N(6)-methyladenine, both in vitro and in vivo. All of these enzymes catalyzed extensive DNA methylation; most notably the Hia5 protein caused the methylation of 61% of the adenines in λ DNA. Kinetic analysis of oligonucleotide methylation suggests that all adenine residues in DNA, with the possible exception of poly(A)-tracts, constitute substrates for the Hia5 and Hin1523 enzymes. Their potential 'sequence specificity' could be summarized as AB or BA (where B = C, G or T). Plasmid DNA isolated from Escherichia coli cells overexpressing these novel DNA methyltransferases was resistant to cleavage by many restriction enzymes sensitive to adenine methylation.
Transcription-inhibition and RNA-binding domains of influenza A virus matrix protein mapped with anti-idiotypic antibodies and synthetic peptides (1989)

We have undertaken by biochemical and immunological experiments to locate the region of the matrix (M1) protein responsible for down-regulating endogenous transcription of A/WSN/33 influenza virus. A more refined map of the antigenic determinants of the M1 protein was obtained by binding of epitope-specific monoclonal antibodies (MAbs) to chemically cleaved fragments. Epitope 2-specific MAb 289/4 and MAb 7E5 reverse transcription inhibition by M1 protein and react with a 4-kilodalton cyanogen bromide fragment extending from amino acid Gly-129 to Gln-164. Anti-idiotype serum immunoglobulin G prepared in rabbits immunized with MAb 289/4 or MAb 7E5 mimicked the action of M1 protein by inhibiting transcription in vitro of influenza virus ribonucleoprotein cores. This transcription-inhibition activity of anti-MAb 7E5 immunoglobulin G and anti-MAb 289/4 immunoglobulin G could be reversed by MAb 7E5 and MAb 289/4 or could be removed by MAb 7E5-Sepharose affinity chromatography. Transcription of influenza virus ribonucleoprotein was inhibited by one of three synthetic oligopeptides, a nonodecapeptide SP3 with an amino acid sequence corresponding to Pro-90 through Thr-108 of the M1 protein. Of all the structural proteins of influenza virus, only NP and M1 showed strong affinity for binding viral RNA or other extraneous RNAs. The 4-kilodalton cyanogen bromide peptide (Gly-129 to Gln-164), exhibited marked affinity for viral RNA, the binding of which was blocked by epitope 2-specific MAb 7E5 but not by MAbs directed to three other epitopes. Viral RNA also bound strongly to the nonodecapeptide SP3 and rather less well to anti-idiotype anti-MAb 7E5; these latter viral RNA-binding reactions were only slightly blocked by preincubation of anti-MAb 7E5 or SP3 with MAb 7E5. These experiments suggest the presence of at least two RNA-binding sites, which also serve as transcription-inhibition sites, centered around amino acid sequences 80 through 109 (epitope 4?) and 129 through 164 (epitope 2) of the 252 amino acid M1 protein of A/WSN/33 influenza virus. A hydropathy plot of the M1 protein calculated by free-energy transfer suggests that the two hydrophilic transcription-inhibition RNA-binding domains are brought into close proximity by an alpha-helix-forming intervening hydrophobic domain.
IP/MPLS OAM: challenges and directions (2005)

This paper reflects different understandings and positions on IP/MPLS OAM functions and management applications, as perceived by representatives from industry and academia. There is a clear effort to improve the state-of-the-art and to apply lessons learnt from the Ethernet/ATM approaches. A series of questions on the short-term, mid-term and long-term directions definitively arises, especially with regard to the separation of control and management functions. The questions mentioned below do not exhaustively cover the topic. Instead, the questions serve as a starting point for a discussion on methodologies to apply, on engineering requirements to consider, and on the technical challenges to resolve harnessing this next stage of evolution of heterogeneous networking. The panel guests present their perception on these issues. What are the lessons learnt from ATM and Ethernet OAM techniques that are oriented to a single network technology? What is equivalent of OAM appropriate for IP/[G]MPLS (it has to be more at link level rather than connection level)? What MPLS MIB information is intended to support OAM functions? What are the challenges on OAM in hybrid and multi-layer networks? How management systems of next generation networks (NGN) and GRID networks make use of the OAM functions and what else is needed to smoothen the control-management interactions? What is the impact of convergent IP networking and autonomic networking on OAM functions and their distribution? How much proactiveness can management applications achieve with and without OAM functionalities.
The Performance Research of Reducing PAR in OFDM Systems in Several Modulation Types (2009)

The Orthogonal Frequency Division Multiplexing (OFDM) is widely used in high speed wireless communication owing to its high utilization rate in frequency spectrum and its availability in anti-multipath, but exorbitant peak-to-average power ratio(PAR) is a big obstacle to utilize it. This paper presents two kinds of common techniques to reduce peak-to-average power ratio, compares their performance in several different modulation types, and puts forward a way of complementary clipping transform. Then a performance simulation of reducing PAR in QPSK is completed.
Leptin increases energy expenditure of a marsupial by inhibition of daily torpor (1998)

Leptin plays an important role in regulating body fat stores of placental mammals, but the contribution of changes in energy expenditure to this adjustment remains controversial. We were interested in how recombinant murine leptin would affect metabolic rate (MR) and body temperature (Tb) of a marsupial mammal (Sminthopsis macroura, 25 g) known to display daily torpor but lacking thermogenetically active brown adipose tissue. In a group of eight animals deprived of food for 1 day at 18 degreesC, leptin treatment halved the duration of torpor bouts (time at Tb < 30 degreesC) and raised the average daily minimum Tb by 4.5 degreesC and minimum MR by 2.2-fold. Leptin treatment thus increased daily energy expenditure by 9%, although MR and Tb during the activity phase were not raised. Body mass was also not affected. These findings in a marsupial suggest that the adjustment of thermoregulatory energy expenditure during the rest phase in accordance with energy availability is a phylogenetically old function of leptin.
Comment on ‘‘Nanosecond photoacoustic studies on ultraviolet laser ablation of organic polymers’’ (1993)

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CzeV615 - a new eclipsing binary (2014)

Discovery of a new eclipsing binary system CzeV615 = BD+09 3111 in the vicinity of an RR Lyrae star, AT Ser, is presented. The variability of the star was detected from CCD measurements with a small telescope. Observations from ASAS-3, NSVS and WISE sky-surveys were used for follow-up analysis. A brightness variation with a period of 1.4869803 d and an amplitude of about 0.1 mag was found. The shapes of light curves in the optical and infrared bands indicate a similar surface temperature for both components. Nevertheless, a period of half the value of the presented period can not be ruled out using the mentioned data.
Invasive behavior of mouse sarcoma cells is inhibited by blocking a 37,000-dalton plasma membrane glycoprotein with Fab fragments. (1984)

Abercrombie 's confronted explant technique was used to study the role of tumor surface antigens in malignant invasion. Plasma membranes were isolated from mouse sarcoma cells ( FS9 ) and a mouse cell line (L929) of the same H-2 haplotype. FS9 cells are highly invasive when confronted with chicken heart fibroblasts, whereas the L929 cells are not [ Abercrombie , M. (1979) Nature (London) 281, 259-262]. The FS9 plasma membranes contained significantly higher concentrations of a 37,000-dalton glycoprotein. When antiserum directed against FS9 plasma membranes was preabsorbed with L929 cells, the antibodies remaining reacted predominantly with the 37,000-dalton antigen. Fab fragment prepared from the preabsorbed antiserum inhibited the invasion of chicken heart fibroblasts by FS9 cells. Fab prepared from a monoclonal antibody directed against the 37,000-dalton antigen also inhibited invasivity , whereas monoclonal antibodies reacting with two other FS9 cell surface antigens did not. The results imply a relationship between the increased concentration of the 37,000-dalton glycoprotein on the surface of the FS9 cells and their invasivity .
Radical Addition Rate Constants to Acrylates and Oxygen:  α-Hydroxy and α-Amino Radicals Produced by Photolysis of Photoinitiators (1999)

Laser flash photolysis of α-hydroxy and α-amino ketones, which are used as photoinitiators in free radical polymerization, lead to the generation of a series of nucleophilic α-hydroxy and α-amino radicals. Absolute addition rate constants of these radicals to n-butylacrylate and oxygen were measured by laser flash photolysis employing an indirect probe technique. Crystal violet and N,N‘-bis(2,5-di-tert-butylphenyl)-3,4,9,10-perylenedicarboximide were used as selective probe molecules for these nucleophilic initiator radicals to measure the addition rate constants to n-butylacrylate and oxygen, respectively. High acrylate addition rate constants of some initiator radicals were found in acetonitrile solution, e.g., dimethylketyl radical (kacrylate = 1.3 × 107 M-1 s-1) and 2-morpholino propan-2-yl radical (kacrylate = 2.9 × 107 M-1 s-1).
Glutathione Transferase in Bacteria: Subunit Composition and Antigenic Characterization (1989)

The presence of glutathione transferase (GST; EC 2.5.1.18) in Escherichia coli ATCC 25922, E. coli ATCC 25422, Proteus vulgaris ATCC 8427, Pseudomonas aeruginosa ATCC 27853, Klebsiella oxytoca CIP 666, K. oxytoca AF 101, Enterobacter cloacae CIP 6085, Serratia marcescens CIP 6755, and Proteus mirabilis AF 2924 was investigated. Using 1-chloro-2,4-dinitrobenzene as substrate, GST activity was found in the glutathione-(GSH-)affinity-purified fraction of all strains tested. SDS-PAGE analysis of GSH-affinity-purified enzyme indicated that the GSTs of all these bacteria are dimers of two identical subunits of Mr about 22,500. Rabbit antiserum directed against the major isoenzyme present in Proteus mirabilis AF 2924, Pm-GST-6.0, was used to investigate the antigenic properties of bacterial GSTs. Western blot analysis indicated that a GST antigenically identical to Pm-GST-6.0 is present in Enterobacter cloacae CIP 6085, Escherichia coli ATCC 25422 and Proteus vulgaris ATCC 8427, but absent in Escherichia coli ATCC 25922, Klebsiella oxytoca CIP 666, K. oxytoca AF 101 and Serratia marcescens CIP 6755. The presence of Pm-GST-6.0, but not mammalian GST, increased the MIC values of amikacin, ampicillin, cefotaxime, cephalothin and nalidixic acid for E. coli ATCC 25922. It is suggested that bacterial GST may represent a defense against the effects of antibiotics.
EFFECT OF HEAT TREATMENT AND THREE PESTICIDES UPON THE GROWTH AND REPRODUCTION OF THE MYCORRHIZAL FUNGUS <i>GLOMUS FASCICULATUS</i> (1979)

S ummary The effects of several heat treatments, a nematicide (DBCP) and two fungicides (ethazole and PCNB) on survival, infection, and sporulation by the mycorrhizal fungus Glomus fasciculatus , were examined. Inocula of G. fasciculatus were killed when exposed for 10 min at 52·5 °C, but not when exposed to 51·5 °C. Although inocula of G. fasciculatus survived a 10 min soaking in PCNB at several concentrations, infection and sporulation on Sudan grass were consistently inhibited by soil drenches with this fungicide. Soil drenches of DBCP (20μg ml −1 H 2 O) or ethazole (50 μg ml −1 H 2 O) applied at the time of inoculation with G. fasciculatus did not significantly affect infection and sporulation by the fungus on Sudan grass. However, soil drenches with DBCP (15 to 20 μg ml −1 H 2 O) and ethazole (10 to 40 μg ml −1 H 2 O) applied 30 to 60 days after inoculation significantly increased infection and sporulation by G. fasciculatus. All data indicate that the pesticides DBCP and ethazole could be used to reduce contamination and to increase the quantity of inoculum of G. fasciculatus.