gebhart/patrepeval huggingface dataset:
Framework for delivering IPTV services over WiMAX wireless networks (2007)

The Internet Protocol Television (IPTV) service is becoming more and more popular among telecommunications companies because it can deliver TV programs anytime anywhere. Based on IP protocol, IPTV features advantages like bandwidth efficiency and ease of management. IPTV supports both broadcast and unicast services like LiveTV and VideoOnDemand. WiMAX wireless system, capable of ensuring high bandwidths and low latencies, is suitable for delivering multimedia services. In addition, it also provides wide area coverage, mobility support, and non-line-of-sight operation. Therefore, WiMAX is a promising solution for delivering IPTV services anytime anywhere, especially to rural areas or remote locations. This paper identifies the challenges in delivering IPTV over WiMAX wireless system and proposes a framework to provide some solutions to those challenges, at MAC and Physical layers. Taking advantage of the WiMAX features, IPTV services can be delivered at low costs and with high audio/video service quality.
Rival Genome Sequencers Celebrate a Milestone Together (2000)

At a White House ceremony on 26 June, two scientific groups, one funded by the government and the other privately funded, announced that they have generated a nearly complete readout of the 3.1 or so billion nucleotides in the human genome. The White House ceremony was more than a celebration; it was also designed to heal a split in the research community. The ceremony brought together leaders of the rival groups in a kind of truce, cooling off a competition that had grown intense in recent months.
Pharmacological study of mequitazine (LM-209) (II): anti-allergic action (1981)

The anti-allergic effect of Mequitazine (LM-209) which was found to have an anti-histaminic activity was investigated in guinea-pigs. The inhibitory activities of LM-209 on the Schultz-Dale reaction and ileum contraction by some mediators released from the sensitized guinea-pig lung were the same as those of clemastine fumarate (CL) but with 5 times the potency. LM-209 and CL, but these activities were less potent than in the case of disodium cromoglycate. The various anaphylactic reactions mediated by IgG in guinea-pigs were inhibited by LM-209, CL and chlorpheniramine maleate (CPM). The homologous PCA mediated IgE in rats was also inhibited by LM-209, CL and CPM, but the duration of the action with LM-209 was markedly longer. In experimentally-induced asthma, the decrease of respiratory rate and volume was significantly inhibited by LM-209, but was not affected by CL. Thus, LM-209 seems to inhibit the allergic reaction mainly by an antagonistic action on allergic mediators.
Toxizität chlororganischer Verbindungen: Einfluß der Einführung von Chlor in organische Moleküle (1994)

Abstract Der „Chlorchemie”︁ wird angelastet, mit ihren Produkten die Umwelt zu verunreinigen und die Gesundheit zu schädigen. In schlichter Folgerung wird gefordert, diesen Zweig der Chemie, der schwierig abzugrenzen ist, „abzuschaffen”︁. Die Bedenken, die zu dieser seit Jahren heftig vorgetragenen Forderung führten, lassen sich wie folgt zusammenfassen: 1. Eine Reihe polychlorierter cyclischer Verbindungen sind sehr stabil und stark lipophil, weshalb sie sich in der Umwelt anreichern und über Nahrungsketten auf den Menschen einwirken. Herausragende Beispiele sind chlorierte Pestizide, Biphenyle sowie Dibenzodioxine und ‐furane. 2. Viele chlorierte Verbindungen sind für Menschen und Tiere toxisch, wobei mutagene und cancerogene Effekte in der Risikobewertung besondere Beachtung finden; mehr und mehr chlororganische Verbindungen werden als krebserzeugend ermittelt und entsprechend eingestuft. Bisher fehlt es an umfassenden toxikologischen Bewertungen chlororganischer Chemikalien. Der vorliegende Aufsatz ist das Ergebnis des Versuches einer systematischen Analyse. Sie kommt zu allgemein‐gültigen Aussagen über Art und Ausmaß der Toxizität der wichtigsten Klassen chlororganischer Verbindungen. Daraus werden Empfehlungen zur Risikoverminderung und ‐vermeidung für Herstellung, beruflichen Umgang und allgemeine Verwendung abgeleitet.
A brief survey on multispectral face recognition and multimodal score fusion (2011)

In this paper, we explore and compare four face recognition methods and their performance with multispectral face images, and further investigate the performance improvement using multimodal score fusion. The four face recognition methods include three classical methods, PCA, LDA and EBGM (elastic bunch graph matching), and one new method, FPB (face pattern byte). The FPB method actually extracts orientational facial features by Gabor wavelet transform and uses Hamming distance for face identification. When the multispectral images from the same subject are available, the identification accuracy and reliability can be significantly enhanced using score fusion. Four score fusion methods, mean fusion, LDA fusion, KNN (k-nearest neighbor) fusion, and HMM (hidden Markov model) fusion are implemented and compared. Our experiments are conducted with the ASUMS face database that currently consists of two-band images (visible and thermal) from 96 subjects. We compare the identification performance of applying the four recognition methods to the two-band face images, and compare the fusion performance of combing the multiple scores from different methods (matcher) and from different bands (modality) of face images. The experimental results show that the face identification rate can achieve 100% when fusing two FPB scores from two-band face images; overall, the FPB method performs the best; the score modality is a key factor in biometric score fusion; when the number of score modalities is fixed, the fusion method becomes next important factor to score fusion; and the HMM fusion is the most reliable score fusion method.
Less Body Fat Accumulation with D-Psicose Diet versus D-Fructose Diet. (2001)

D-Psicose (D-ribo-2-hexulose), a C-3 epimer of D-fructose, is present in small quantities in commercial carbohydrates and agricultural products. To evaluate the possibility of D-psicose as low-energy sugar substitute, we studied the effects on body fat accumulation of D-psicose compared with cellulose or D-fructose in rats. Wistar male rats were fed experimental diets including 5% D-psicose, cellulose or D-fructose for 21 days. Abdominal adipose tissue weight was significantly lower (p<0.05) in rats fed D-psicose than in those fed D-fructose. Gene expression of uncoupling protein-1 and β3-adrenergic receptor in the brown adipose tissue did not differ among the dietary groups. Fatty acid synthase and glucose 6-phosphate dehydrogenase activities in the liver were significantly lower (p<0.05) in rats fed D-psicose, whereas lipoprotein lipase activities in the heart, soleus muscle, perirenal adipose tissue, and subcutaneous adipose tissue did not differ. These results suggest that supplementation of D-psicose in the diet suppresses hepatic lipogenic enzyme activities. The lower abdominal fat accumulation in rats fed D-psicose might have resulted from lower lipogenesis in the liver. D-Psicose could prove to be a superior sugar substitute.
El plaer a llegir i les lectures obligatòries a l'ensenyament secundari (1993)

The data showed improved rates of screening of clinic attendees and declining trends in sero-reactivity over time. The introduction of point-of-care syphilis tests may have contributed to the improved coverage of syphilis screening. The ICST may be considered for initial syphilis screening at other resource-constrained primary care sites in India such as ante-natal clinics and other KP interventions.
Radioactive stents (2005)

Treatment for heart disease has changed considerably over the last several decades. One of the most important advances has been the advent of catheter-based techniques that allow minimally invasive solutions for treating ischemic heart disease. After Charles Dotter introduced transluminal angioplasty in the 1960s, coronary angioplasty was pioneered by Andreas Gruentzig following development of his balloon catheter in 1974. More recently, stents and covered stents have proven to be important adjuncts to Gruentzig’s original procedure.
Angiotensin II analogs. 6. Stereochemical factors in the 5 position influencing pressor activity. 1 (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAngiotensin II analogs. 6. Stereochemical factors in the 5 position influencing pressor activity. 1Eugene C. Jorgensen, Sambasiva R. Rapaka, Graham C. Windridge, and Thomas C. LeeCite this: J. Med. Chem. 1971, 14, 10, 899–903Publication Date (Print):October 1, 1971Publication History Published online1 May 2002Published inissue 1 October 1971https://doi.org/10.1021/jm00292a001Request reuse permissionsArticle Views68Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (683 KB) Get e-Alertsclose Get e-Alerts
Is dynamic compilation possible for embedded systems? (2015)

JIT compilation and dynamic compilation are powerful techniques allowing to delay the final code generation to the runtime. There is many benefits: improved portability, virtual machine security, etc.
Scientific Promise: Reflections on Nano‐Hype (2007)

This chapter contains sections titled: Introduction The Role of Expectations in Processes and Outcomes Linear Causal Models Perfection Elusive Truth Scientific Knowledge The Role of Beliefs The Case for Reason, Stability, and Interdisciplinarity
National Pressure Ulcer Advisory Panel's updated pressure ulcer staging system. (2007)

The National Pressure Ulcer Advisory Panel has updated the definition of a pressure ulcer and the stages of pressure ulcers based on current research and expert opinion solicited from hundreds of clinicians, educators, and researchers across the country. The amount of anatomical tissue loss described with each stage has not changed. New definitions were drafted to achieve accuracy, clarity, succinctness, clinical utility, and discrimination between and among the definitions of other pressure ulcer stages and other types of wounds. Deep tissue injury was also added as a distinct pressure ulcer in this updated system.
Parallel data analysis directly on scientific file formats (2014)

Scientific experiments and large-scale simulations produce massive amounts of data. Many of these scientific datasets are arrays, and are stored in file formats such as HDF5 and NetCDF. Although scientific data management systems, such as SciDB, are designed to manipulate arrays, there are challenges in integrating these systems into existing analysis workflows. Major barriers include the expensive task of preparing and loading data before querying, and converting the final results to a format that is understood by the existing post-processing and visualization tools. As a consequence, integrating a data management system into an existing scientific data analysis workflow is time-consuming and requires extensive user involvement. In this paper, we present the design of a new scientific data analysis system that efficiently processes queries directly over data stored in the HDF5 file format. This design choice eliminates the tedious and error-prone data loading process, and makes the query results readily available to the next processing steps of the analysis workflow. Our design leverages the increasing main memory capacities found in supercomputers through bitmap indexing and in-memory query execution. In addition, query processing over the HDF5 data format can be effortlessly parallelized to utilize the ample concurrency available in large-scale supercomputers and modern parallel file systems. We evaluate the performance of our system on a large supercomputing system and experiment with both a synthetic dataset and a real cosmology observation dataset. Our system frequently outperforms the relational database system that the cosmology team currently uses, and is more than 10X faster than Hive when processing data in parallel. Overall, by eliminating the data loading step, our query processing system is more effective in supporting in situ scientific analysis workflows.
Photoluminescence and electroluminescence from porous silicon (1996)

The properties and origins of the red, blue and infrared photoluminescence bands of porous silicon are reviewed and discussed in the light of the models that have been proposed to explain the experimental and theoretical results. The red band is due to quantum confinement possibly supplemented by surface states; the blue band is linked to the presence of silicon dioxide; the infrared band is correlated with dangling bonds and bandgap luminescence in large crystallites. The fabrication and characterization of light-emitting devices made of porous silicon are reported and discussed with respect to critical issues such as the device stability, efficiency, modulation speed, emission wavelength, and compatibility with microelectronic processing.
High-Level Language Support for Programming Distributed Systems J. S. Auerbach D. F. Bacon A. P. Goldberg G. S. Goldszmidt A. S. Gopal M. T. Kennedy A. R. Lowry J. R. Russell W. Silverman R. E. Strom (1992)

This paper presents a strategy to simplify the programming of heterogeneous distributed systems. Our approach is based on integrating a high-level distributed programming model, called the process model, directly into programming languages. Distributed applications written in such languages are portable across different environments, are shorter, and are simpler to develop than similar applications developed using conventional approaches. In this paper, we discuss the process model, and present overviews of Hermes and Concert/C, two Ianguages that implement this model. Hermes is a secure, representation-independent language designed explicitly around the process model. Concert/C is the C language augmented with a small set of extensions to support the process model while allowing reuse of existing C code. Hermes has been prototyped; an implementation of Concert/C is in development.
<i>Clcn2</i>encodes the hyperpolarization-activated chloride channel in the ducts of mouse salivary glands (2008)

Transepithelial Cl(-) transport in salivary gland ducts is a major component of the ion reabsorption process, the final stage of saliva production. It was previously demonstrated that a Cl(-) current with the biophysical properties of ClC-2 channels dominates the Cl(-) conductance of unstimulated granular duct cells in the mouse submandibular gland. This inward-rectifying Cl(-) current is activated by hyperpolarization and elevated intracellular Cl(-) concentration. Here we show that ClC-2 immunolocalized to the basolateral region of acinar and duct cells in mouse salivary glands, whereas its expression was most robust in granular and striated duct cells. Consistent with this observation, nearly 10-fold larger ClC-2-like currents were observed in granular duct cells than the acinar cells obtained from submandibular glands. The loss of inward-rectifying Cl(-) current in cells from Clcn2(-/-) mice confirmed the molecular identity of the channel responsible for these currents as ClC-2. Nevertheless, both in vivo and ex vivo fluid secretion assays failed to identify significant changes in the ion composition, osmolality, or salivary flow rate of Clcn2(-/-) mice. Additionally, neither a compensatory increase in Cftr Cl(-) channel protein expression nor in Cftr-like Cl(-) currents were detected in Clcn2 null mice, nor did it appear that ClC-2 was important for blood-organ barrier function. We conclude that ClC-2 is the inward-rectifying Cl(-) channel in duct cells, but its expression is not apparently required for the ion reabsorption or the barrier function of salivary ductal epithelium.
Oligomeric Interaction of Hepatitis C Virus NS5B Is Critical for Catalytic Activity of RNA-dependent RNA Polymerase (2002)

HCV NS5B is an RNA-dependent RNA polymerase (RdRP), a central catalytic enzyme for HCV replication, which has the "palm and fingers" substructure. We recently identified five novel residues critical for RdRP activity (Qin, W., Yamashita, T., Shirota, Y., Lin, Y., Wei, W., and Murakami, S. (2001) Hepatology 33, 728-737). Among them, GLU-18 and His-502, far from the catalytic center, may be involved in conformational change(s) for RdRP activity as addressed in some palm and fingers enzymes. We examined the possibility that NS5B is oligomerized, and we could detect the interaction between two different tagged NS5B proteins in vitro and transiently expressed in mammalian cells. By scanning 27 clustered and then point alanine substitutions in vivo and in vitro, Glu-18 and His-502 were found to be critical for the homomeric interaction in vivo and in vitro, strongly suggesting a close relationship between the oligomerization and RdRP activity of NS5B. All mutants with substitutions at these two residues failed to bind wild type NS5B, however E18H interacted with H502E in vitro and in vivo. Interestingly, the NS5B protein with E18H or H502E did not exhibit RdRP activity, but a mixture of the two mutant proteins did. These results clearly indicate that two residues of HCV NS5B are critical for the oligomerization that is prerequisite to RdRP activity.
The effect of <i>N</i>‐methylprotoporphyrin and succinyl‐acetone on the regulation of heme biosynthesis in chicken hepatocytes in culture (1983)

The essential features of hepatic protoporphyria, namely inhibition of ferrochelatase, accumulation of protoporphyrin and stimulation of 5-aminolevulinic acid synthase (ALA-S) were all obtained by treating chicken hepatocytes in culture with small doses of N-methylprotoporphyrin. Both N-methylprotoporphyrin and succinyl-acetone, another inhibitor of heme biosynthesis, stimulated ALA-S when given on their own and also enhanced the stimulation of ALA-S caused by phenobarbital.
Functional display of foreign protein on surface of <i>Escherichia coli</i> using N‐terminal domain of ice nucleation protein (2003)

We investigated the ability of the N-terminal domain of InaK, an ice nucleation protein from Pseudomonas syringae KCTC1832, to act as an anchoring motif for the display of foreign proteins on the Escherichia coli cell surface. Total expression level and surface display efficiency of green fluorescent protein (GFP) was compared following their fusion with either the N-terminal domain of InaK (InaK-N), or with the known truncated InaK containing both N- and C-terminal domains (InaK-NC). We report that the InaK-N/GFP fusion protein showed a similar cell surface display efficiency ( approximately 50%) as InaK-NC/GFP, demonstrating that the InaK N-terminal region alone can direct translocation of foreign proteins to the cell surface and can be employed as a potential cell surface display motif. Moreover, InaK-N/GFP showed the highest levels of total expression and surface display based on unit cell density. InaK-N was also successful in directing cell surface display of organophosphorus hydrolase (OPH), confirming its ability to act as a display motif.
Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis (2011)

Although uncertainty remains, little evidence exists to suggest that any of the investigated drugs are safe in cardiovascular terms. Naproxen seemed least harmful. Cardiovascular risk needs to be taken into account when prescribing any non-steroidal anti-inflammatory drug.
The Saccharomyces cerevisiae YAK1 gene encodes a protein kinase that is induced by arrest early in the cell cycle. (1991)

Null mutations in the gene YAK1, which encodes a protein with sequence homology to known protein kinases, suppress the cell cycle arrest phenotype of mutants lacking the cyclic AMP-dependent protein kinase (A kinase). That is, loss of the YAK1 protein specifically compensates for loss of the A kinase. Here, we show that the protein encoded by YAK1 has protein kinase activity. Yak1 kinase activity is low during exponential growth but is induced at least 50-fold by arrest of cells prior to the completion of S phase. Induction is not observed by arrest at stages later in the cell cycle. Depending on the arrest regimen, induction can occur either by an increase in Yak1 protein levels or by an increase in Yak1 specific activity. Finally, an increase in Yak1 protein levels causes growth arrest of cells with attenuated A kinase activity. These results suggest that Yak1 acts in a pathway parallel to that of the A kinase to negatively regulate cell proliferation.
Amorphous/nanocrystalline silicon biosensor for the specific identification of unamplified nucleic acid sequences using gold nanoparticle probes (2007)

Amorphous/nanocrystalline silicon pi′ii′n devices fabricated on micromachined glass substrates are integrated with oligonucleotide-derivatized gold nanoparticles for a colorimetric detection method. The method enables the specific detection and quantification of unamplified nucleic acid sequences (DNA and RNA) without the need to functionalize the glass surface, allowing for resolution of single nucleotide differences between DNA and RNA sequences—single nucleotide polymorphism and mutation detection. The detector’s substrate is glass and the sample is directly applied on the back side of the biosensor, ensuring a direct optical coupling of the assays with a concomitant maximum photon capture and the possibility to reuse the sensor.
Genetic analysis of a relationship between macrocyclic lactone and benzimidazole anthelmintic selection on Haemonchus contortus (2008)

Although MLs exert their antiparasitic effect through binding to ligand-gated chloride channels, benzimidazoles interact with beta-tubulin. These genetic analyses indicate that there is a correlation between exposure and/or resistance to MLs and an increase in the frequency of the beta-tubulin alleles containing codons, which are determinant for benzimidazole resistance. ML use may predispose parasitic nematodes to benzimidazole resistance. This has major implications for parasite control programs dependent on MLs/benzimidazole rotations and on the use of ML/benzimidazole combination therapy, such as for human lymphatic filariasis and nematode control in ruminant livestock.