gebhart/patrepeval huggingface dataset:
Comparative genetic mapping of allotetraploid cotton and its diploid progenitors (1999)

Allotetraploid cotton species (Gossypium) belong to a 1-2 million year old lineage that reunited diploid genomes that diverged from each other 5-10 million years ago. To characterize genome evolution in the diploids and allotetraploids, comparative RFLP mapping was used to construct genetic maps for the allotetraploids (AD genome; n = 26) and diploids (A and D genomes; n = 13). Comparisons among the 13 suites of homoeologous linkage groups permitted comparisons of synteny and gene order. Two reciprocal translocations were confirmed involving four allotetraploid A t genome chromosomes, as was a translocation between the two extant A genome diploids. Nineteen locus order differences were detected among the two diploid and two allotetraploid genomes. Conservation of colinear linkage groups among the four genomes indicates that allopolyploidy in Gossypium was not accompanied by extensive chromosomal rearrangement. Many inversions include duplicated loci, suggesting that the processes that gave rise to inversions are not fully conservative. Allotetraploid A t and D t genomes and the A and D diploid genomes are recombinationally equivalent despite a nearly two-fold difference in physical size. Polyploidization in Gossypium is associated with enhanced recombination, as genetic lengths for allotetraploid genomes are over 50% greater than those of their diploid counterparts.Key words: restriction fragment length polymorphism (RFLP), Gossypium, evolution, polyploidy.
LA FORMACIÓN PERMANENTE DE LOS INSPECTORES DE EDUCACIÓN: RETÓRICA, REALIDAD Y FUTURO (2006)

El presente articulo pretende ser una reflexion inicial que fomente el debate profesional sobre un tema que en el actual momento educativo apenas tiene relevancia ni en el contexto educativo espanol, ni en el internacional (europeo e iberoamericano): el perfeccionamiento profesional de los inspectores de educacion y de los supervisores sigue siendo una tarea pendiente en la mayor parte de los sistemas educativos. Al menos en Espana se ha llegado a establecer de una forma un tanto retorica que la formacion permanente de los inspectores de educacion es tanto un derecho como un deber para que desarrollen plenamente sus funciones y puedan ser agentes que contribuyan, con otros, al cambio educativo en los centros.
Sequence Analysis of the Florfenicol Resistance Gene Encoded in the Transferable R‐Plasmid of a Fish Pathogen, <i>Pasteurella piscicida</i> (1996)

The florfenicol resistance gene (pp-flo) derived from a transferable R-plasmid of Pasteurella piscicida consisted of 1,122 nucleotides, and the predicted amino acid sequence showed 47.4% identity to that of a non-enzymatic chloramphenicol resistance gene (cmlA). The pp-flo gene was located in the downstream region of the sulfonamide resistance gene of the transferable R-plasmid.
Introducción a las Lecciones XVII-XX: Cuerpo, comunidad, lenguaje, mundo (2019)

Aporia, International Journal for Philosophical Investigations, its main mission is to promote the knowledge and study of philosophy, its origin, tradition and development, through original research articles in which an academic discussion on any philosophical problem and its possible solutions are presented
Signal analysis of externally linear filters (2003)

The circuit equations of an externally linear filter realization are nonlinear state-space equations. In this paper, a method to test if a nonlinear system is externally linear and to calculate its transfer function is proposed. The method transforms the nonlinear system to an externally equivalent linear system (described by linear state-space equations), which can be solved to obtain the transfer function. As an illustrative example, a log-domain filter is analyzed.
Associations of grip strength with cardiovascular, respiratory, and cancer outcomes and all cause mortality: prospective cohort study of half a million UK Biobank participants (2018)

Higher grip strength was associated with a range of health outcomes and improved prediction of an office based risk score. Further work on the use of grip strength in risk scores or risk screening is needed to establish its potential clinical utility.
Messias, Moses Redivivus, Menschensohn. By Aage Bentzen. Skizzen zum Thema Weissagung und Erfüllung. Abhandlung zur Theologie des Alten und Neuen Testaments. Zwingli-Verlag, Zürich (1948). pp. 80 Fr. 7. (1949)

Messias, Moses Redivivus, Menschensohn. By Aage Bentzen. Skizzen zum Thema Weissagung und Erfüllung. Abhandlung zur Theologie des Alten und Neuen Testaments. Zwingli-Verlag, Zürich (1948). pp. 80 Fr. 7. - Volume 2 Issue 4
Coherent Matrix Completion (2013)

Matrix completion, i.e., the exact and provable recovery of a low-rank matrix from a small subset of its elements, is currently only known to be possible if the matrix satisfies a restrictive structural constraint---known as {\em incoherence}---on its row and column spaces. In these cases, the subset of elements is sampled uniformly at random. In this paper, we show that {\em any} rank-$ r $ $ n$-by-$ n $ matrix can be exactly recovered from as few as $O(nr \log^2 n)$ randomly chosen elements, provided this random choice is made according to a {\em specific biased distribution}: the probability of any element being sampled should be proportional to the sum of the leverage scores of the corresponding row, and column. Perhaps equally important, we show that this specific form of sampling is nearly necessary, in a natural precise sense; this implies that other perhaps more intuitive sampling schemes fail. We further establish three ways to use the above result for the setting when leverage scores are not known \textit{a priori}: (a) a sampling strategy for the case when only one of the row or column spaces are incoherent, (b) a two-phase sampling procedure for general matrices that first samples to estimate leverage scores followed by sampling for exact recovery, and (c) an analysis showing the advantages of weighted nuclear/trace-norm minimization over the vanilla un-weighted formulation for the case of non-uniform sampling.
Phosphorous‐Functionalized Bis(acyl)phosphane Oxides for Surface Modification (2012)

International audience
Sound-Ranging Technique for Locating Supersonic Missiles (1966)

Mathematical formulations are developed that can be used with conventional sound-ranging data for determining a first approximation of a point on a trajectory of a vertically falling supersonic missile. The most interesting feature of the development is that it requires only a single four-microphone square array.
Inhibitory Effect of the Extract of Prunus mume Sieb. et Zucc. on Vero-toxin Production by Enterohemorrhagic Escherichia coli O157:H7. (2001)

The effect of Prunus mume Sieb. et Zucc.(Prunus mume) extract on the production of verotoxins by enterohemorrhagic Escherichia coli O157: H7 (EHEC) was investigated. The amount of vero-toxins (ng/ml) produced was calculated and revised according to the ratio between the amount of vero-toxins detected in the test tube and the viable cell numbers of EHEC. Production of EHEC vero-toxins was inhibited by the extract of the fruit of Prunus mume at 156 mg/ml. This inhibitory effect was obtained at a dose below the minimal inhibitory concentration (625 mg/ml) of the Prunus mume extract, indicating that this extract seems to act on the vero-toxin-producing cells of EHEC before vero-toxins are produced.
Learning to Distinguish Hypernyms and Co-Hyponyms (2014)

This work is concerned with distinguishing different semantic relations which exist between distributionally similar words. We compare a novel approach based on training a linear Support Vector Machine on pairs of feature vectors with state-of-the-art methods based on distributional similarity. We show that the new supervised approach does better even when there is minimal information about the target words in the training data, giving a 15% reduction in error rate over unsupervised approaches.
Synthesis of <sup>64</sup>Cu-Labeled Magnetic Nanoparticles for Multimodal Imaging (2008)

Complementary imaging modalities provide more information than either method alone can yield and we have developed a dual-mode imaging probe for combined magnetic resonance (MR) and positron emission tomography (PET) imaging. We have developed dual-mode PET/MRI active probes targeted to vascular inflammation and present synthesis of (1) an aliphatic amine polystyrene bead and (2) a novel superparamagnetic iron oxide nanoparticle targeted to macrophages that were both coupled to positron-emitting copper-64 isotopes. The amine groups of the polystyrene beads were directly conjugated with an amine-reactive form (isothiocyanate) of aza-macrocycle 1,4,7,10-tetraazacyclo-dodecane-1,4,7,10-tetraacetic acid (DOTA). Iron oxide nanoparticles are dextran sulfate coated, and the surface was modified to contain aldehyde groups to conjugate to an amine-activated DOTA. Incorporation of chelated Cu-64 to nanoparticles under these conditions, which is routinely used to couple DOTA to macromolecules, was unexpectedly difficult and illustrates that traditional conjugation methods do not always work in a nanoparticle environment. Therefore, we developed new methods to couple Cu-64 to nanoparticles and demonstrate successful labeling to a range of nanoparticle types. We obtained labeling yields of 24% for the amine polystyrene beads and 21% radiolabeling yield for the anionic dextran sulfate iron oxide nanoparticles. The new coupling chemistry can be generalized for attaching chelated metals to other nanoparticle platforms.
Requirement of sense transcription for homology‐dependent virus resistance and <i>trans</i>‐inactivation (1997)

Summary Transgenic tobacco plants carrying post‐transcriptionally, silenced (L) or conditionally high‐expressing (H c ) cauliflower mosaic virus 35S promoter:β‐glucuronidase ( GUS ) transgenes were tested for their ability to support replication of a potato virus X derivative with an inserted GUS coding sequence (PVX.GUS). PVX.GUS accumulated to high levels on non‐transformed tobacco. In contrast, both L and H c tobacco were resistant to PVX.GUS. Another line, 271, carries a 35S‐driven transgene that can down‐regulate transcription from any other 35S promoter in trans . When the 271 locus was introduced into the L and H c lines, virus resistance was suppressed. The L tobacco line also trans ‐inactivated transient GUS expression from an extra‐chromosomal T‐DNA delivered by Agrobacterium . This trans ‐inactivation was not observed when the 271 locus was present. In addition, it was found that the 271 locus suppressed the virus resistance normally conferred by a 35S‐driven transgene derived from the PVX replicase open reading frame. These results indicate that sense transcription is required for a transgene to condition homology‐dependent virus resistance and post‐transcriptional trans ‐inactivation.
Glucose dehydrogenase from the thermoacidophilic archaebacterium <i>Sulfolobus solfataricus</i> (1986)

Glucose dehydrogenase has been purified to homogeneity from cell extracts of the extreme thermoacidophilic archaebacterium Sulfolobus solfataricus. The enzyme utilizes both NAD+ and NADP+ as coenzyme and catalyses the oxidation of several monosaccharides to the corresponding glyconic acid. Substrate specificity and oxidation rate depend on the coenzyme present; when NAD+ is used, the enzyme binds and oxidizes specifically sugars presenting equatorial orientation of hydroxy groups at C-2, C-3 and C-4. The Mr of the native enzyme is 124,000 and decreases to about 60,000 in the presence of 6 M-guanidinium chloride and to about 30,000 in the presence of 5% (w/v) SDS. The enzyme shows maximal activity at pH 9, 77 degrees C and 20 mM-Mg2+, -Mn2+ or -Ca2+ and is fairly stable in the presence of chaotropic agents and water-miscible organic solvents such as methanol or acetone.
Tungsten oxide nanopowders and nanorods prepared by a modified plasma arc gas condensation technique (2007)

Tungsten oxide nanopowders and nanorods were synthesized by using a modified plasma arc gas condensation technique that involved the introduction of a mixed gas with controllable partial O2 pressure into a gas condensation system. Experimental results showed that yellow and blue tungsten oxide nanopowders, prepared under an Ar to O2 ratios of 1: 1 and 100: 1, exhibited a major WO3 phase and W19O55 phase, respectively. The nanopowders grew into W5O14-phase nanorods along the [001] direction when H2 was used as the reduction gas. [doi:10.2320/matertrans.M2009068]
Nutritional strategies to reduce environmental emissions from nonruminants (2002)

The amount of nutrients (i.e., N, P, Zn, and Cu) and associated odors emitted from production animals into the environment can be modulated by several different nutritional strategies, but their practical application is dependent on costs and biological limitations. In general, nutrient excretion may be reduced by avoiding the overfeeding of specific nutrients or by using nutritional manipulations to enhance nutrient utilization in the animal. Loss to the environment can be avoided by manufacturing and handling the feed in a pelletized form that will minimize waste and improve feed/gain. Other strategies for minimizing nutrient losses include: 1) the development of feeding programs that are specific for sex and strain of the animal; 2) increasing the number of feed phases to better meet the animal's age-related requirements; 3) formulating diets to include the minimal amounts of nutrients required to satisfy production goals; 4) meeting the animal's amino acid requirements; 5) using synthetic amino acid supplements to feed to reduce N emission; 6) using feed ingredients with high digestibility and nutrient bioavailability; and 7) formulating diets based on nutrient availability instead of total nutrient content. Nutrient digestibility of feedstuffs is dependent on processing conditions, genetic characteristics of the grains and oilseeds, and the presence of nutritional antagonists in specific feedstuffs used in the diet. Feed ingredients that lead to odor production can be avoided (e.g., fishmeal and some easily fermentable feed ingredients). Feed additives, such as antibiotics, nonstarch polysaccharides, direct-fed microbials, organic acids, microbial enzymes (i.e., phytase, carbohydrases, and proteases) can be used to increase the digestibility and absorption of nutrients or to modulate the microflora. Finally, a cost factor for the control or disposal of nutrients or odor should be considered in the feed formulation to optimize the various nutritional strategies discussed above. Regardless of biological and economic limitations, significant reductions in nutrient and odor emission from nonruminants can be achieved by appropriate nutritional strategies, but response may differ for swine and poultry.
Improvements of an up-conversion NaYF/sub 4/:Er/sup 3+/ phosphor/silicon solar cell system for an enhanced response in the near-infrared (2005)

This study investigates the performance of up-converting rare-earth phosphors doped with different trivalent erbium (Er/sup 3+/) concentrations: 2%, 20%, 50%, 100%, and with the addition of 20% ytterbium (Yb). The dominant up-conversion (UC) mechanisms within these phosphors are discussed and examined using photoluminescence and the spectral response from a bifacial silicon solar cell. The most efficient phosphor examined had 20% Er doping and gave a maximum external quantum efficiency close to 3.4% with 6 mW 1523 nm laser excitation. The subsequent system internal quantum efficiency (accounting for reflection losses within the cell) is calculated to be over 5.7%.
Clickable, Photodegradable Hydrogels to Dynamically Modulate Valvular Interstitial Cell Phenotype (2014)

Biophysical cues are widely recognized to influence cell phenotype. While this evidence was established using static substrates, there is growing interest in creating stimulus-responsive biomaterials that better recapitulate the dynamic extracellular matrix. Here, a clickable, photodegradable hydrogel substrate that allows the user to precisely control substrate elasticity and topography in situ is presented. The hydrogels are synthesized by reacting an 8-arm poly(ethylene glycol) alkyne with an azide-functionalized photodegradable crosslinker. The utility of this platform by exploiting its photoresponsive properties to modulate the phenotype of porcine aortic valvular interstitial cells (VICs) is demonstrated. First, VIC phenotype is monitored, in response to initial substratum modulus and static topographic cues. Higher modulus (E ≈ 15 kPa) substrates induce higher levels of activation (≈70% myofibroblasts) versus soft (E ≈ 3 kPa) substrates (≈20% myofibroblasts). Microtopographies that induce VIC alignment and elongation on low modulus substrates also stimulate activation. Finally, VIC phenotype is monitored in response to sequential in situ manipulations. The results illustrate that VIC activation on stiff surfaces (≈70% myofibroblasts) can be partially reversed by reducing surface modulus (≈30% myofibroblats) and subsequently re-activated by anisotropic topographies (≈60% myofibroblasts). Such dynamic substrates afford unique opportunities to decipher the complex role of matrix cues on the plasticity of VIC activation.
Transition Metal Oxide Gels and Colloids (1982)

Gels and colloids are very widespread in nature. The familiar dessert jelly, the vitreous humor that fills the interior of the eye, marmalade, clays, india ink, milk, and blood serum are gels or colloids. They are also important intermediates in the manufacture of rubber and plastics, and are used in the laboratory for chromatography and electrophoresis. Gels and colloids have been studied for more than a century, and Graham (1861) is usually regarded as the founder of colloid science. Nevertheless, most of the physical chemistry of gels has been developed only during the last 40 years, mainly by Flory at Stanford University (1). These studies deal mostly with organic polymers. There is much less work on inorganic compounds (2) and, to our knowledge, this paper is the first attempt to review transition metal oxide gels and colloids. In that field, most of the work has been done by French groups during the last four years. The uniqueness of this work lies in its considering transition metal oxide gels as new materials having specific physical properties. A gel being a form of matter intermediate between liquid and solid, its electrical, optical, or magnetic properties could lead to new applications in the field of materials SCIence.
The anti‐amnesic and neuroprotective effects of donepezil against amyloid β<sub>25‐35</sub>peptide‐induced toxicity in mice involve an interaction with the<i>σ</i><sub>1</sub>receptor (2006)

The potent anti-amnesic and neuroprotective effects of donepezil against Abeta(25-35)-induced toxicity involve both its cholinergic and sigma(1) agonistic properties. This dual action may explain its sustained activity compared to other ChE inhibitors.
Dislocation of a Type I Membrane Protein Requires Interactions between Membrane-spanning Segments within the Lipid Bilayer (2003)

The human cytomegalovirus gene product US11 causes rapid degradation of class I major histocompatibility complex (MHCI) heavy chains by inducing their dislocation from the endoplasmic reticulum (ER) and subsequent degradation by the proteasome. This set of reactions resembles the endogenous cellular quality control pathway that removes misfolded or unassembled proteins from the ER. We show that the transmembrane domain (TMD) of US11 is essential for MHCI heavy chain dislocation, but dispensable for MHCI binding. A Gln residue at position 192 in the US11 TMD is crucial for the ubiquitination and degradation of MHCI heavy chains. Cells that express US11 TMD mutants allow formation of MHCI-beta2m complexes, but their rate of egress from the ER is significantly impaired. Further mutagenesis data are consistent with the presence of an alpha-helical structure in the US11 TMD essential for MHCI heavy chain dislocation. The failure of US11 TMD mutants to catalyze dislocation is a unique instance in which a polar residue in the TMD of a type I membrane protein is required for that protein's function. Targeting of MHCI heavy chains for dislocation by US11 thus requires the formation of interhelical hydrogen bonds within the ER membrane.
Percutaneous Balloon Valvuloplasty: A New Method for Treating Congenital Pulmonary-Valve Stenosis (1982)

TRANSLUMINAL balloon angioplasty has been increasingly accepted as a nonsurgical technique for dilatation of stenotic arteries in the peripheral, renal, and coronary circulations.1 2 3 4 5 6 The physical principles governing balloon angioplasty7 depend on transmission of a controlled radial force through a rigid balloon. The characteristics of the stenotic tissue determine the effectiveness of the dilatation process.Application of the balloon-dilatation principle to intracardiac valves has not been described. However, Semb et al. have relieved congenital pulmonary-valve stenosis by pulling a carbon dioxide-filled balloon from the pulmonary artery to the right ventricle.8 We thought that balloon valvuloplasty of the congenitally stenotic pulmonary valve . . .
Single‐Crystal Hexagonal Disks and Rings of ZnO: Low‐Temperature, Large‐Scale Synthesis and Growth Mechanism (2004)

Solution-phase synthesis of single-crystal ZnO disks and rings was achieved in high yield at low temperature (70–90 °C) by using an anionic surfactant as a template. The reaction can be controlled by means of the growth temperature and the molar ratio of reagents to favor formation of disks or rings. A growth mechanism is proposed on the basis of structural information provided by SEM and TEM.
Inhibition of Pancreatic Lipase by Phenolic Acids -Examination in vitro (1996)

The influence of addition 2,4,6,8, and 10 microM of benzoic and cinnamic acids and selected phenolic acids (salicylic, p-hydroxybenzoic, gentisic, protocatechuic, vanillic, syringic, o-coumaric, p-coumaric, caffeic, ferulic, sinapic) on the activity of pancreatic lipase was examined in vitro. The strongest inhibition activities were observed with caffeic, ferulic and benzoic acid, while sinapic and gentisic acids produced the lowest inhibition.
Toward Positive Literacy Outcomes for Students with Significant Developmental Disabilities (2005)

Three classroom teachers and their 23 students with significant developmental disabilities were studied across 8 weeks as a new literacy and communication instructional program, MEville to WEville, was implemented. Before and after the implementation, the students were tested on a variety of literacy measures, their teachers were interviewed, and each classroom was observed. During the implementation, each classroom was observed at least once each week for a total of 35 hours of observation. Measured outcomes and benefits of the MEville to WEville program were evident for the students in each classroom. Students demonstrated increases in their attempts to initiate and sustain social interactions, and improvements in their literacy skills and understandings. Although observed differences did not reach statistical significance, the outcomes represent a significant practical difference for the children in the current study.
Coagulation Factor Xa Modulates Airway Remodeling in a Murine Model of Asthma (2006)

The results of this study introduce a novel participant in the asthmatic response and indicate that factor Xa functions in airway remodeling in asthma by stimulating mucin production, through regulation of amphiregulin expression and collagen deposition.
A Method for Systems Design Using Precedence Relationships: An Application to Automotive Brake Systems (1990)

HD28 .M414 no.3208-, 90,