gebhart/patrepeval huggingface dataset:
Investigation and Analysis on the Talents of Science and Technology Service Industry (2011)

After studying the questionnaires to the HR managers of some science and technology service organizations in Guangdong,the paper finds that the talents are not only in short supply,but also in a low level at their knowledge and qualification.The paper strongly suggests that it is urgent to train the talents with high education,rich experience and good capacity.
MPPT control algorithms for wind power generation based on voltage disturbance (2008)

Wind power generation system operates in variable speed constant frequency condition. If the wind turbine is under controlled working around the optimal tip-speed ratio, the wind turbine can achieve relatively high conversion efficiency, and generated energy can be obviously increased, then propeller regulation can be simplified. Current source inverter (CSI) is adopted as the inverter of direct-drive wind power generation system could, which reduce system cost and raise system efficiency. In this paper, ldquohill climbing methodrdquo maximum power point tracking (MPPT) is taken as the core and CSI dc side voltage is used as control variable in direct-drive wind power generation system. The effectiveness of the model and method is verified by simulation results.
Suppression of p38 MAPK and JNK via Akt-mediated Inhibition of Apoptosis Signal-regulating Kinase 1 Constitutes a Core Component of the β-Cell Pro-survival Effects of Glucose-dependent Insulinotropic Polypeptide (2009)

Glucose-dependent insulinotropic polypeptide (GIP) potentiates glucose-stimulated insulin secretion, insulin biosynthesis, and beta-cell proliferation and survival. In previous studies GIP was shown to promote beta-cell survival by modulating the activity of multiple signaling modules and regulating gene transcription of pro- and anti-apoptotic bcl-2 family proteins. We have now evaluated the mechanisms by which GIP regulates the dynamic interactions between cytoplasmic bcl-2 family members and the mitochondria in INS-1 cells during apoptosis induced by treatment with staurosporine (STS), an activator of the mitochondria-mediated apoptotic pathway. STS induced translocation of bad and bimEL, activation of mitochondrial bax, release of mitochondrial cytochrome c, cleavage of caspase-3, and apoptosis. Each response was significantly diminished by GIP. Using selective enzyme inhibitors, overexpression of dominant-negative Akt, and Akt siRNA, it was demonstrated that GIP promoted beta-cell survival via Akt-dependent suppression of p38 MAPK and JNK and that combined inhibition was sufficient to explain the entire pro-survival responses to GIP during STS treatment. This signaling pathway also explained the pro-survival effects of GIP on INS-1 cells exposed to two other promoters of stress: thapsigargin (endoplasmic reticulum stress) and etoposide (genotoxic stress). Importantly, we discovered that GIP suppressed p38 MAPK and JNK via Akt-mediated changes in the phosphorylation state of the apoptosis signal-regulating kinase 1 in INS-1 cells and human islets, resulting in inhibition of its activity. Inhibition of apoptosis by GIP is therefore mediated via a key pathway involving Akt-dependent inhibition of apoptosis signal-regulating kinase 1, which subsequently prevents the pro-apoptotic actions of p38 MAPK and JNK.
Ruhpolding, ein praktisches Lösungsbeispiel des neuzeitlichen Sozialtourismus (1955)

Die Arbeitsgemeinschaft Touropa, die sich aus den bedeutenden Organisationen: Reisebüro Dr. Degener, Hapag‐Lloyd‐Reisebüro, Deutsches Reisebüro (DER) und Amtliches Bayerisches Reisebüro zusammensetzt, besitzt im deutschen Fremdenverkehr eine starke Stellung. Erstmals 1954 führte die Touropa ihre jährliche grosse Arbeitstagung im Ausland durch. Für diesen Kongress wählte Dr. Degener, der dynamische Leiter dieser Organisation, die Seele der Touropa, Luzern als Stand‐ und Arbeitsort. Während einer Woche weilten gegen tausend Fachleute und Journalisten in unserer Stadt, und seit dieser prächtig verlaufenen und denkwürdigen Touropa‐Versammlung erfreuen wir uns besonders angenehmer Beziehungen zu Dr. Degener und zu seinen tüchtigen Mitarbeitern.
Tubal sterilization. A historical review. (1985)

During the 1970s there was a fivefold worldwide increase in the number of sterilizations. Sterilization has emerged in many countries as the most popular method of family planning for couples over 30 years of age. This paper reviews the developments in tubal sterilization, with special emphasis on the early years and the development of laparoscopic techniques.
Antithrombin III Kumamoto: Identification of a Point Mutation and Genotype Analysis of the Family (1990)

We previously reported a variant antithrombin III (AT III Kumamoto) associated with a 31-year-old female who suffered from recurrent thrombotic episodes. To define the molecular basis for the variant AT III, we used a combination of genomic amplification followed by cloning, sequencing, and hybridization with allele-specific oligonucleotide probes. We obtained evidence for a cytosine to thymine transition in exon 2 (codon 47) of the AT III gene in the proband. This mutation converts arginine 47 to cysteine. Oligonucleotide hybridization procedures were used for confirmation of the mutation and for genotype analysis of the family members.
Use of a differential subtraction method to identify genes that characterize the phenotype of cultured rheumatoid arthritis synoviocytes (1998)

A general method for the identification of differences in patterns of gene expression revealed that cultured RA fibroblastoid synoviocytes overexpress certain proinflammatory genes that are potentially relevant to lymphocyte and monocyte entry and interactions. The features of the genes identified in these mesenchymal cells suggest that they facilitate localization of immune reactions to the joint through leukocyte chemokinesis, cell-cell adhesion, and matrix specialization. The further characterization of these genes should help in resolving whether this phenotype is the consequence of modulation and imprinting by an inflammatory milieu or, more likely, whether it reflects the intrinsic lineage characteristics of intimal lining synoviocytes.
Protein Arrays Step Out of DNA's Shadow (2000)

As technical obstacles yield, en masse protein testing is poised to take one of biochemistry's most exciting techniques into the heart of cellular chemistry. On page 1760 of this issue, researchers report creating arrays of over 10,000 proteins on a piece of glass just half the size of a microscope slide. They then used their arrays to study a variety of protein functions, including identifying members of the array that bind to other free-floating proteins and to small, druglike molecules.
Modular verification of global module invariants in object-oriented programs (2004)

Modules and objects both contain variables whose values may be constrained by invariants. For example, in the object-oriented languages Java and C#, a module is a class and its static fields, and an object is an instance of a class and its instance variables. The invariants of modules work differently both from the invariants of objects alone and from the invariants of modules in a procedural language. This paper presents a methodology for module invariants in an objectoriented setting. The methodology is sound, prescribes an initialization order of a program’s modules, supports the dynamic loading of modules and classes, and is amenable to static, modular checking.
Deposition-based patterning by area-selective deposition: Dielectric-on-dielectric and metal-on-metal using integrated Atomic Layer Deposition and thermally-driven Atomic Layer Etching (Conference Presentation) (2020)

Deposition-based patterning is becoming an important need in advanced manufacturing. Several new approaches are emerging where chemical etching is being coupled with atomic layer deposition to achieve area-selective deposition of dielectrics and metals. During ALD, selectivity is generally lost when undesired nuclei form on the targeted non-growth surface. These undesired nuclei can sometimes be removed by periodic etching, improving the overall selectivity. However, it is not known to what extent these coupled deposition/etching sequences can proceed while maintaining good selectivity. As desirable deposition and etching reactions proceed, other changes in the process can occur to enhance unwanted nucleation and/or impede desired etching, thereby limiting the net selectivity. Recent experiments in our lab have used in-situ probes to explore coupled thermal ALD and ALE super-cycles, performed sequentially under isothermal conditions in a single reaction chamber, to achieve area selective deposition of TiO2 on SiO2 with hydrogen-terminated silicon (100) as the desired non-growth surface. We find that as ALD/ALE super-cycles proceed, small changes occur in the ALD and ALE reactions, particularly during the transition from ALD to ALE, or from ALE to ALD. Likewise, a new thermally-driven ALE process for tungsten has been applied in ALD/ALE super-cycles to improve W ASD. In this case, the ALE process alters the ALD surface leading to significant changes in the ALD. Modeling studies allow us to quantitatively analyze the ASD results and compare our findings to other known approaches. These insights will be helpful to understand opportunities and challenges in advanced deposition-based patterning.
Design and implementation of a boost power factor correction stage operated in mixed-conduction mode (2011)

This paper focuses on the implementation of a controller-based power factor correction (PFC) boost converter. Both CCM and DCM modes are operated in the mixed-conduction mode with fixed switching frequency. The load condition is determined by detecting the load current. The converter operates in CCM mode when the load is heavy. It switches to the DCM mode when the converter detects the load is light. The measured results show that the proposed dual-mode converter control strategy has good performance in power factor correction and power conversion efficiency.
ChemInform Abstract: PYRROLIZIDINE ALKALOIDS. SYNTHESIS OF 13,13‐DIMETHYL‐1,2‐DIDEHYDROCROTALANINE (1980)

Abstract Durch alkalische Hydrolyse von Retrorsin erhaltenes (+)‐Retr.onecin (I) reagiert mit dem Dimethylglutarsäureanhydrid (II) in quantitativer Ausbeute zu einem 2:1‐Gemisch der Verbindungen (IIIa) und (IIIb), deren 2‐Pyridinthiolester in siedendem Dimethylformamid die gesuchte Verbindung (IV) als Hauptprodukt liefern.
Interaction of Phenylisopropylamines with Central 5-HT2 Receptors (1989)

A QSAR investigation of 27 4-substituted derivatives of 1-(2,5-dimethoxyphenyl)-2-aminopropane (i.e., 2,5-DMA) reveals that the lipophilic character of the 4-substituent is a primary determining factor for 5-HT2 receptor affinity. The length (size/shape ?) of the substituent may also be important. Previous studies have shown that certain 2,5-DMAs act as 5-HT2 agonists whereas preliminary data suggest others may act as antagonists (or at least as mixed agonist-antagonists). Intrinsic activity may be related to electronic as well as lipophilic properties of the 4-substituent.
Modeling e-logistics for urban B2C in Europe (2005)

Major cities need to carry out good delivery operations that coexist with the rest of urban functions. The efficiency in city organisation depends directly on the proper management of logistic networks. In this context, Urban Logistics is born to improve the efficiency in public facilities dealing with the organisation of supply networks, especially in urban freight transport networks. This paper quantitatively models supply chains in the vehicle routing problem with time windows, especially in the delivery of e-commerce companies. Orders are placed through internet, but deliveries are made at the customer’s home. The model takes special account of the effect produced on logistics variables (distances, times, costs, shipments, stops, etc.), by the way in which orders are received, and includes the delivery in time windows in urban areas.\nPlanners should design parking space and loading/unloading procedures so that the deliveries are made efficiently and with little traffic perturbation, and the industry should start getting ready to understand the high cost of this quality of service: the “picking” process has a high cost that cannot be assumed in high volumes and everyday the good (the street is contemplated as a scarce social good) and bad (double parking, bus lane blocking, etc. causing additional traffic congestion) use of the streets will likely cost more money. An application to Barcelona, Spain, for the food distribution sector (supermarkets) shows that, for the previously stated reasons, the current industry procedures are only feasible for very low demand share (less than 10%).
Rhythmic similarity of music based on dynamic periodicity warping (2008)

This paper introduces a new way to measure rhythmic similarity between two musical pieces using periodicity spectra. In order to detect similarity for pieces of different tempi, the linearity of the warping path between their spectra serves as a measure of their rhythmic similarity. Using a modified kNN classification approach on two datasets, the proposed measure provides comparable classification accuracy (82.1%) to the best of widely used measures (85.5%) for the first dataset; For the second dataset, which is characterized by a large variance of tempi, the proposed measure outperforms all reference measures, reaching an accuracy of 69.0%, while the best of the other measures reaches 53.8%. Moreover, the presented technique works fully automatically, and no information regarding tempo is needed.
The Many Forks in FOXO's Road (2003)

The FOXO family of transcription factors constitute an evolutionarily conserved subgroup within the larger family known as winged helix or Forkhead transcriptional regulators. Building upon work in the nematode, researchers have uncovered a role for these proteins in a diverse set of cellular responses that include glucose metabolism, stress response, cell cycle regulation, and apoptosis. At the organismal level, FOXO transcription factors are believed to function in various pathological processes ranging from cancer and diabetes to organismal aging. A number of studies have also shed light on the signaling pathways that regulate FOXO activity in response to external stimuli and have identified multiple FOXO target genes that mediate this varied set of biological responses.
A Calibrated Method of Magnitude and Phase Errors in Digital Vector Modulation (2010)

In the use of digital vector modulation technology in broadening the instantaneous bandwidth of baseband signal,it's inevitable to generate mirror signal due to magnitude and phase errors introduced by the nonideal characteristic of I/Q channel,thus the spectrum purity of output signal is deteriorated dramatically,and it is difficult for the receiver to recognize the signal.In order to match the engineering requirement,it is necessary to calibrate the magnitude and phase errors.In this paper,the magnitude and phase errors of the system are measured first,then an all-pass filter and a low-pass filter are designed to calibrate the phase and magnitude errors respectively.The experiment result indicates that calibration method could effectively increase the image rejection rate and improve the quality of output signal.
Technical, economic and institutional evalutation of adopting directional drilling by Kengen, Kenya (2002)

KenGen envisages that adoption of directional drilling to target vertical permeability for its future production wells will bear substantial financial benefits arising from a possible increase in average well productivity and a reduction of the surface steam gathering pipe network. The fact that great disparity in productivity has been noted between adjacent wells suggests that vertical or near-vertical structural permeability may be important in this system. Efforts are underway to acquire the capacity to undertake this form of drilling. In this report a comprehensive technological overview and a study of experiences of various operators in the geothermal arena has been undertaken, in order to build a concise understanding of the technology. Directional drilling technology has successfully and widely been employed in the geothermal sector, in particular to target vertical/semi-vertical permeability and for environmental reasons. Use of downhole positive displacement motors with a bent housing / bent sub, and measurement while drilling (MWD) instruments is now the standard practice. Studies undertaken have put to question that in general directional wells are better producers than vertical ones. Multiple-leg (forked) wells and larger diameter casings, two emerging technologies, have promised significant production improvements. An increase in production of up to 200% has been reported in wells with larger diameter casings. Drilling directional wells will cost about 22-41% more and may increase a 64 MWe project cost by between 2.8 and 6% if well productivity does not improve. For an increase in average production from 3.5 MWe to 5 MWe per well as projected, a saving on project cost of between 3.4 and 6% could be realised. An increase of about 0.8 MWe per well, would make this option economically viable. Adopting larger diameter casings (13d” OD production casing and 9e” OD liner) would increase the well cost by about 16% and could increase the project cost by about 3.1% per well. Savings of about 4.6% would be realised if 5 MWe average well output is achieved and an increase of 0.5 MWe would make this option economically viable. It is recommended that KenGen apply directional drilling technology to optimise exploitation of Longonot and Suswa prospects. A new drilling rig and on the job training for KenGen’s drillers will be necessary. Hire of directional drilling services will be greatly advantageous to KenGen directional drilling operations.
High‐brightness saturated‐color shutter technology (1997)

Abstract— We report a new switchable RGB color shutter that provides better color saturation, a 400% improvement in color band transmission over dye‐based shutters, and submillisecond transition times. The improvements are achieved via a complementary color polarizer and achromatic LC polarization rotator technologies.
How a service-oriented architecture may change the software development process (2010)

Introduction Software development practices have evolved substantially during the past decade. As so called "agile" approaches have gained more acceptance and applications have become progressively more distributed in terms of their physical execution and the development of components, the service-oriented approach to IT architecture has become an important alternative to traditional software development. Another impetus for the trend to a Service-Oriented Architecture (SOA) is provided by enterprise system vendors as they are incorporating the service-oriented paradigm into their products. Substantial efforts related to open standards (such as Web service standards) and open source products (such as open source enterprise service bus, development tools) are further driving a service-oriented approach for information systems. A key question is whether SOA adopters are going to be ready for this change and whether they can provide a technical and an organizational environment in which SOA-related technologies can be leveraged to their full potential. There is some indication that currently this may not be the case. In fact, some organizations that have embarked on SOA-related projects early have experienced disappointments. As with other technology waves, the important question is not whether SOA is inherently a good or a bad idea, but rather how it can be done right in a given context. This article tries to answer this question with respect to the software development process. While much of the literature, both in academia and industry, has focused on business implications of SOA, technological realization, architectural issues, and implementation guidelines, few publications have addressed the impact of SOA on the software development process and its methodology. As with any organizational change, modifications to software development processes or practices entail switching cost. Therefore, individuals as well as organizations are inclined to stay with "proven" methodologies, although adjustments based on task requirements and technology characteristics should be key drivers for the methodology choice and are needed to help adopters leverage the full potential of SOA. This article examines the differences and discusses which parts of development process and methodology may require adjustments to effectively leverage a SOA. It presents the results of a field study suggesting changes to software development practices that are necessary to accommodate the unique properties of the service-oriented approach.
Carotid artery intraplaque hemorrhage and stenotic velocity. (1993)

Peak systolic velocity is significantly higher in patients with intraplaque hemorrhage. The specificity and sensitivity of a peak systolic velocity of > 420 cm/sec in predicting intraplaque hemorrhage remains to be determined.
La labor educativa en el marco de las competencias de los organismos electorales en América Latina (2012)

Electoral bodies, given their expertise in Latin America, have the power and opportunities to foster educational programs for the promotion of democracy, to a greater or lesser extent as determined by its functional competence. The article suggests lines of action brought about by recent Latin American experience in the field and suggests that there are important conceptual, methodological and didactic resources, , already developed that can serve to boost and support educational programs for democracy with the participation of these electoral institutions
Research Note: Overselling with Opportunistic Cancellations (1999)

In many business sectors such as airlines, hotels, trucking, and media advertising, customers' arrivals and willingness to pay are uncertain. Managers must decide whether to quote a price low enough to guarantee early sales, or to quote a higher price and risk that some units remain unsold. In allocating capacity, they face a trade-off between two types of potential losses; (1) Yield loss—selling at a low price, and losing a better price later, and (2) Spoilage loss—waiting in vain to sell at a high price, and losing the opportunity of an earlier low price offer. Yield loss means that consumers who value the product most do not get to use it, and spoilage loss means that valuable products are wasted because no consumers get to use them. Sellers typically hedge against the risk of spoilage loss by selling some units early at low prices, and against the risk of yield loss by blocking some units in hope of selling them later at a high price. In this paper we show that the use of overselling with opportunistic cancellations can increase expected profits and improve allocation efficiency. Under this strategy, the seller deliberately oversells capacity if high-paying consumers show up, even when capacity is already fully booked. The seller then cancels the sale to some low-paying customers while providing them with appropriate compensation. We derive a new rule to optimally allocate capacity to consumers when overselling is used, and show that overselling helps limit the potential yield and spoilage losses. Yield loss is reduced because the seller can capture more high-paying customers by compensating low-paying customers who give up their right to the product. Spoilage loss is reduced because the compensation decreases the price spread perceived by the seller, and as a result, the seller is less anxious to speculate and “block” units. Overselling with opportunistic cancellations assures that the product will be sold to consumers who value it most. This means that “everybody wins”, and resources are allocated more efficiently than in conventional selling.