gebhart/patrepeval huggingface dataset:
Towards a global cellular service (2002)

During a time when cellular systems are being deployed in massive scale worldwide, international roaming is becoming increasingly important. This raises end user's interest in having access to one and the same global cellular service. Today this is being addressed within the context of FPLMTS. But the end user interest is already here, long before FPLMTS will be introduced. This paper proposes a solution that will enable cellular subscribers to experience a global cellular service, taking into account the current generation of different cellular standards, as well as the introduction of the third generation standard (FPLMTS).
Partial prevention of glutathione depletion in rats following acute intoxication with diethylmaleate. (1993)

To assess the ability of L-2-oxothiazolidine-4-carboxylate (OTC) to stimulate the biosynthesis of glutathione (GSH) in non-fasted male rats, the time-courses of GSH and cysteine contents were studied in liver, kidney, heart and brain, following a single intraperitoneal injection of OTC (5 mmol/kg), with or without co-administration of the GSH depletor diethylmaleate (3 mmol/kg). In the absence of diethylmaleate, OTC did not change the GSH or cysteine content of heart and kidney. The liver was the only organ where systemic administration of OTC resulted in a fast and quasi-linear increase in GSH as a function of time, with no appreciable lag-time. A maximal, i.e. 2.1-fold increase in liver GSH was induced by OTC at the times corresponding to the low GSH values of the diurnal cycle observed in control rats. A smaller, i.e. 1.4-fold increase in brain GSH was observed after 6 hours. A marked increase in cysteine always preceded that of GSH in liver and brain. In the liver, the OTC-mediated stimulation of GSH biosynthesis was optimal when cysteine delivery was achieved at the onset of the cysteine decrease that was observed in the diurnal cycle of control rats. These results support the view that cysteine is a limiting factor in the biosynthesis of GSH. Following an acute dose of diethylmaleate (3 mmol/kg), OTC afforded a general and significant protection of rat tissues against GSH depletion.(ABSTRACT TRUNCATED AT 250 WORDS)
User-centred multimodal reminders for assistive living (2011)

While there has been a lot of research on the usability of reminders and alarms in the work context, the home has been somewhat neglected despite the importance of reminder systems for telecare and assistive living systems. We conducted a comprehensive mixed-methods study into the requirements for useable and acceptable reminders in the home. The study consisted of a questionnaire (N=379), 6 focus groups, and 7 home tour interviews. Our results highlight the need for highly flexible and contextualized multimodal and multi-device reminder solutions that build on existing successful strategies for remembering in and around the home. We suggest that developers of home care reminder systems should design for diversity, context, priorities, autonomy, shared spaces, and optimal care.
Flexible and Porous Nanocellulose Aerogels with High Loadings of Metal–Organic‐Framework Particles for Separations Applications (2016)

Flexible and porous aerogels are obtained by combining functional metal-organic frameworks (MOFs) and structural cellulose nanocrystals via a straightforward water-based sol-gel process, followed by freeze-drying. The aerogels have a hierarchical porous structure with controllable MOF loading up to 50 wt%. These hybrid materials can be used as absorbents for water purification.
QED: Quick Error Detection tests for effective post-silicon validation (2010)

Long error detection latency, the time elapsed between the occurrence of an error caused by a bug and its manifestation as a system-level failure, is a major challenge in post-silicon validation of robust systems. In this paper, we present a new technique called Quick Error Detection (QED), which transforms existing post-silicon validation tests into new validation tests that significantly reduce error detection latency. QED transformations allow flexible tradeoffs between error detection latency, coverage, and complexity, and can be implemented in software with little or no hardware changes. Results obtained from hardware experiments on quad-core Intel <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">®</sup> Core™ i7 hardware platforms and from simulations on a multi-core MIPS processor design demonstrate that: 1. QED significantly improves error detection latencies by six orders of magnitude, i.e., from billions of cycles to a few thousand cycles or less. 2. QED transformations do not degrade the coverage of validation tests as estimated empirically by measuring the maximum operating frequencies over a wide range of operating voltage points. 3. QED tests improve coverage by detecting errors that escape the original non-QED tests.
HIV Protease Inhibitor-Related Lipodystrophy Syndrome (2000)

Human immunodeficiency virus (HIV) protease inhibitor (PI) therapy is frequently associated with a syndrome increasingly referred to as lipodystrophy syndrome, which is characterized by peripheral lipoatrophy, fat accumulation within the abdomen, in the breasts of women, and over the cervical vertebrae ("buffalo hump"), hyperlipidemia, and insulin resistance. In the largest study to date, peripheral lipoatrophy (an estimated 0.35-kg fat loss per month overall from the face, limbs, and upper trunk) was observed in association with all licensed PIs after a median 10 months of PI therapy. Diabetes mellitus type II appears to be a related, but less common, adverse effect. The lipodystrophy syndrome may be a result of the inhibition of 2 proteins involved in lipid metabolism that have significant homology to the catalytic site of HIV protease-namely, cytoplasmic retinoic acid binding protein type 1 and low density lipoprotein-receptor-related protein.
Reactions of phosphonic acid esters with nucleophiles. I. Hydrolysis (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of phosphonic acid esters with nucleophiles. I. HydrolysisE. J. Behrman, Michael J. Biallas, Herbert J. Brass, John Oelhaf Edwards, and Martin IsaksCite this: J. Org. Chem. 1970, 35, 9, 3063–3069Publication Date (Print):September 1, 1970Publication History Published online1 May 2002Published inissue 1 September 1970https://pubs.acs.org/doi/10.1021/jo00834a043https://doi.org/10.1021/jo00834a043research-articleACS PublicationsRequest reuse permissionsArticle Views442Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effect of the two tachykinin antagonists, SR 48968 and SR 140333, on cough induced by citric acid in the unanaesthetized guinea pig (1995)

It is now well-established that sensory nerves stimulation in the airway induces bronchoconstriction and inflammation, but also protective reflexes, such as coughing. These effects are mediated through the release of tachykinins (substance P and neurokinin A) and we have recently shown that SR 48968, a tachykinin NK2-receptor antagonist, inhibited cough induced by citric acid. In this paper, we have studied the effects of SR 48968 administered by aerosol. We have also investigated the effects of SR 140333, a tachykinin NK1-receptor antagonist, and the combination of both SR 48968 and SR140333 to determine whether tachykinin NK1 receptors are involved in cough. Finally, we have studied the combined effects of SR 48968 and salbutamol to find out whether the antitussive effect of SR 48968 is a consequence of the inhibition of bronchoconstriction. Unanaesthetized guinea-pigs were placed in a transparent chamber and exposed to an aerosol of citric acid (0.4 M). The number of coughs was counted by visual inspection and by determination of sounds and pressure variations in the chamber. By the aerosol route, SR 48968 was an efficient antitussive and 16 times more potent than codeine. SR 140333 (0.1-1 mg.kg-1 i.p.) did not exert any antitussive effect but it potentiated the maximal effect induced by SR 48968. Finally, salbutamol, in a dose (0.3 mg.kg-1) which inhibits bronchoconstriction, but not cough induced by citric acid, did not modify the antitussive effect of SR 48968.(ABSTRACT TRUNCATED AT 250 WORDS)
Effects of Pilot Injection Strategy on Combustion and Emission Characteristics in Gasoline Compression Ignition (2017)

In this paper, the effects of pilot injection strategies, including various pilot injection timings and masses, on the combustion and emission characteristics of gasoline compression ignition are investigated in a multi-cylinder heavy duty diesel engine with the aim of reducing peak pressure rise rate while improving thermal efficiency and exhaust emissions. The results show that the HRRPI, max (peak heat release rate of pilot injection) becomes more sensitive to the change of pilot-main interval as the pilot injection mass increases, and the sensitivity of HRRPI, max to the change of pilot injection mass increases with the reduction of pilot-main interval. PHRRMI, max (peak premixed heat release rate of main injection) decreases with the decrease of pilot-main interval and the increase of pilot injection mass. The PRRmax (peak pressure rise rate) and soot emission can be improved by 60.2% and 42.3% respectively, while still maintaining similar BSFC with optimized pilot injection strategy compared to single injection.
Glycoproteins with Type Common and Type Specific Antigenic Sites Excreted from Cells Infected with Herpes Simplex Virus Types 1 and 2 (1980)

Agar immunodiffusion tests demonstrated that BHK 21 cells infected with either HSV I or HSV 2 release only a few HSV-specified antigens into the extracellular fluid (infected cell released polypeptides-ICRP). Neutralization blocking experiments showed that the majority of antigens/(including the Band II common antigen) involved as target sites in antibody-mediated virus neutralization are present in the ICRP of both HSV I and HSV 2.SDS-PAGE identified six regions of virus-specified proteins in the ICRP from both HSV I- and HSV 2-infected BHK cells. All these specifically released proteins are glycosylated, although to varying degrees. The SDS-PAGE profiles of HSV I and HSV 2 ICRP are different but do show some similarities, the most notable being a highly glycosylated protein with an estimated mol. wt. of 50,000 to 54,000 in HSV I ICRP and 52,000 to 56,000 in HSV 2 ICRP. Immune precipitation demonstrated that these two proteins contain the Band II antigenic site. Similar studies showed that the major type I specific antigenic site, which is involved as a target site in the neutralization of virus infectivity, is located in the highest mol. wt. glycoprotein region of HSV I ICRP and has a similar mobility to the VP7/8 region of purified enveloped virus.
Novel Widely Tunable Monolithically Integrated Laser Source (2015)

We report a novel type of monolithically integrated tunable semiconductor laser. The tuning is achieved by three intracavity Mach-Zehnder interferometers, realized in passive waveguides and using voltage-controlled electro-optic phase modulators requiring only four control voltages. The potential of the design is demonstrated by a realized laser system that shows an optical linewidth of 363 kHz, output power of 3 mW, and a record tuning range of 74.3 nm. Such a continuous wavelength span is in excess of any monolithic semiconductor laser reported up to date. Precision of the tuning mechanism is demonstrated by a scan over a 0.89-GHz-wide absorption line of acetylene. The laser design is suitable for a number of applications, including gas spectroscopy, telecommunication, and optical coherence tomography. The laser has been fabricated in a multi-project wafer run on an indium phosphide-based generic photonic foundry platform and demonstrates the potential of these technology platforms.
Single fully differential current conveyor biquad filters (2003)

The authors present two new filter biquads based on the recently introduced fully differential current conveyor (FDCCII). The biquads use a single FDCCII, two grounded resistors and two grounded capacitors, which are the minimum components necessary to realise a second-order filtering response (low-pass, high-pass, band-pass, band-reject, and all-pass). This is unlike biquads reported by El-Adawy et al. (2000), which employ more active and passive components. Simulation results are included, validating the theoretical analysis.
Combined Surface Plasmon and Classical Waveguiding through Metamaterial Fiber Design (2009)

A metamaterial integration for fiber optics, leading to a dual effect of surface plasmon and classical waveguiding, is presented along with experimental potentiality. We theoretically propose a metamaterial fiber in which, depending on the wavelength (from ultraviolet to infrared) and the particular metamaterial composition, one can transmit information through surface plasmon mediated or classical waveguidance. The metamaterial can be used as the core or cladding of a fiber which allows waveguidance through a subwavelength geometry.
Scanning Thermoacoustic Tomograhy in Biological Tissue (2000)

Thermoacoustic tomography in the microwave region is explored to image biological tissue. When short-pulse electromagnetic energy is deposited into tissue, acoustic waves are generated due to thermoelastic expansion. The microwave-induced acoustic wave is detected with a focused ultrasonic detector. Each time-domain signal from the ultrasonic transducer represents a one-dimensional image along the acoustic axis. Scanning the system generates multi-dimensional images. The time-domain acoustic signal was simulated theoretically and measured experimentally, where the theoretical and experimental results were in good agreement. Two-dimensional tomographic images of biological tissue were obtained experimentally. Thermoacoustic tomography combines the advantage of microwaves in imaging contrast and the advantage of acoustic waves in imaging resolution.
Functional Modulation of the Sodium Pump: The Regulatory Proteins “Fixit” (2003)

Proteins of the FXYD family act as tissue-specific regulators of the Na-K-ATPase. They are small hydrophobic type I proteins with a single-transmembrane span containing an extracellular invariant FXYD sequence. FXYD proteins are not an integral part of the Na-K-ATPase but function to modulate its catalytic properties by molecular interactions with specific Na-K-ATPase domains.
Hydrogen diffusion in aluminium at high temperatures (1983)

The diffusion of hydrogen in aluminium has been measured by the permeation method using a quadrupole mass spectrometer. Hydrogen was introduced by gas phase charging in the temperature range of 300-400 degrees C, and by electrochemical charging at room temperature. It was found that the diffusivity of hydrogen depends on the relative concentration of vacancies to the dissolved hydrogen concentration. The activation energy for the diffusion of hydrogen was found to be 0.61-0.62 eV at high temperatures where the concentration of vacancies was much higher than that of dissolved hydrogen. The value is near the migration energy of a vacancy in aluminium. On the other hand, at room temperature where the hydrogen showed a diffusivity considerably larger than that extrapolated from high temperatures. These facts suggest that hydrogen in aluminium migrates together with a vacancy at high temperatures due to a large binding energy between them.
Expression and Activity of Histone Deacetylases in Human Asthmatic Airways (2002)

Asthma is a chronic inflammatory disease that is characterized by increased expression of multiple inflammatory genes. Chromatin modification plays a critical role in the regulation of these genes. Acetyaltion of histones by histone acetyltransferases (HATs) is associated with increased gene transcription, whereas hypocetylation induced by histone deacetylases (HDACs) is associated with suppression of gene expression. We have examined the expression and activity of HATs and HDACs in bronchial biopsies from normal subjects and subjects with asthma. There was no difference in the site of HDAC1-HDAC6 expression between normal subjects and subjects with asthma, but subjects with asthma had reduced HDAC enzymatic activity and reduced HDAC1 and HDAC2 protein expression, as measured by Western blotting. In contrast, subjects with asthma treated with inhaled steroids were found to have greater HDAC activity than untreated subjects with asthma, although still lower than control subjects. In contrast, although there was no change in the site of HAT (CREB binding protein and p300/CREB binding protein-associated factor) expression, HAT activity was increased in subjects with asthma. HAT activity was reduced to control levels in subjects with asthma treated with inhaled steroids. The increase in HAT activity and reduced HDAC activity in asthma may underlie the increased expression of multiple inflammatory genes, and this is reversed, at least in part, by treatment with inhaled steroids.
Investigation of Centrifugal Pumping Rotor Blades as a Means of Vortex Diffusion (2015)

High-resolution flow visualization (FV) and particle image velocimetry (PIV) measurements were taken to document the development and evolution of a rotor wake in ground effect. In particular, the current work focuses on diffusing the tip vortices, through the use of centrifugal pumping, before they can fully form and reach the ground. A baseline non-pumping blade set and four different pumping blade designs were tested. All the pumping blade designs utilized the same centrifugal air flow mechanism, but the internal flow exited the blade at angles of 0°, 30°, 45°, and 60° above the horizontal axis. Detailed flow field measurements were performed for regions of interest near the rotor and in the near-wall region to understand the development and evolution of the trailed tip vortices in ground effect. All the blades sets were tested in a hovering state in ground effect at a blade loading coefficient, CT/σ, of 0.080. Additional measurements were also performed on the baseline and 0° pumping blade design at a reduced blade loading coefficient of CT/σ = 0.053 to examine the effect mass flow rate had on tip vortex diffusion. All the pumping blade designs were found to incur a power penalty, which resulted from the exit slots at the tip increasing the profile losses. The 30°, 45°, and 60° pumping blade designs were found to have a degraded performance as compared to that of the 0° pumping blade, which is believed to result from negative thrust effects associated with the mass flow of the air out the exit slots. When operating at the higher thrust condition, the pumping blade designs were found to merely prolong the initial formation of the tip vortices as opposed to completely diffusing them. However, when the 0° pumping blade was operated at the lower thrust condition the tip vortices were found to be more diffused, with significant reduction in the upwash velocity near the ground.
On Demand Retrieval of Crowdsourced Mobile Video (2014)

The proliferation of mobile cameras has popularized social sharing of videos captured at events such as sports matches, art performances, and lectures. Due to bandwidth and energy constraints, it is often not efficient or desirable to upload all captured videos to a server for sharing immediately after capturing. We propose a pull-based, on-demand mobile video sharing system that allows user to share video captured at an event, with two novel components: 1) a lightweight video metadata extraction algorithm running on the smartphones that considers both temporal and spatial features, including sensor (compass) readings and point-of-interest of the content and 2) a video selection algorithm, running on the server, that responds to user queries considering both accuracy of the retrieved video and the upload cost of the smartphones. Our evaluation results show up to four times improvement in upload cost and 52% improvement in subjective quality over three baseline algorithms that consider only either cost or accuracy.
Biosensor based on microstructured optical fiber Bragg grating for DNA detection (2014)

The numerical analysis and the experimental characterization of a novel bio-sensing approach based on a functionalized Penta microstructured optical fiber with a Bragg grating (Penta BG-MOF) for specific DNA target sequences detection have been demonstrated. The inner surface of the fiber has been functionalized using PNA probes, OligoNucleotides mimic that are well suited for specific DNA target sequences detection. The measurements of fluorescence have proved the successful hybridization. After the hybridization has occurred, oligonucleotide functionalized TiO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> Nano Particles (TiO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> NPs) were infiltrated and used to form a sandwich-like system to achieve signal amplification. The numerical analysis is essential to evaluate physical parameters of the functionalized fiber: the refractive index and the thickness of the layer. The calculated shift of the reflected high order mode Bragg grating has a good agreement with the experimental result.
Bonding Trends in Lewis Acid Adducts of S<sub>4</sub>N<sub>4</sub> – X‐ray Structure of TeCl<sub>4</sub>·S<sub>4</sub>N<sub>4</sub> (2006)

Abstract Tetrasulfur tetranitride and tellurium tetrachloride react in dichloromethane to form a 1:1 adduct TeCl 4 · S 4 N 4 ( 1 ). The crystal structure of 1 shows that TeCl 4 is bonded to the S 4 N 4 ring through a Te–N linkage. As a consequence, the transannular S ··· S bonds in S 4 N 4 are broken and the molecule assumes an open, monocyclic conformation. The Te–N bond of 2.16(1) Å is slightly longer than the single bond. The S–N bonds span a range of 1.55(1)–1.67(1) Å. The adduct 1 was also characterized by mass spectrometry and Raman spectroscopy. The bonding and spectroscopic properties of 1 are compared by DFT calculations at the B3PW91/(RLC ECP) level of theory with those of BF 3 · S 4 N 4 ( 2 ), SO 3 · S 4 N 4 ( 3 ), AsF 5 · S 4 N 4 ( 4 ), SbCl 5 · S 4 N 4 ( 5 ) for which experimental structural information is available. The structural and bonding trends in TeF 4 · S 4 N 4 ( 6 ), TeBr 4 · S 4 N 4 ( 7 ), and SeX 4 · S 4 N 4 [X = F ( 8 ), Cl ( 9 ), Br ( 10 )] are also discussed. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)