gebhart/patrepeval huggingface dataset:
Increased Dose Density Is Feasible: A Pilot Study of Adjuvant Epirubicin and Cyclophosphamide followed by Paclitaxel, at 10- or 11-Day Intervals with Filgrastim Support in Women with Breast Cancer (2007)

Therapy with EC for four cycles followed by paclitaxel for four cycles at 10- to 11-day intervals is feasible. The approximately 30% reduction in intertreatment interval compared with every 14-day treatment could increase the efficacy of adjuvant chemotherapy.
Laser Techniques in Photovoltaic Research (1979)

High-power laser pulses were used to replace the conventional high temperature furnace processing for the p-n junction formation step in high speed, low cost solar cell fabrication. Three different approaches to junction formation were tested: (1) laser annealing of ion-implanted Si in which laser radiation is used to remove the radiation damage and to recover the electrical activity in the implanted layer; (2) a process in which a thin film of dopant is first deposited on the substrate and then incorporated into the near-surface region by laser-induced diffusion; and (3) a process in which a heavily doped amorphous silicon layer is deposited on the Si substrate and epitaxially regrown from the melted substrate layer by laser radiation. All three methods were found to provide suitable candidates for high efficiency Si solar cells.
Effects of different biosolids treatment systems on pathogen and pathogen indicator reduction (1997)

In this study, the effectiveness of different treatment systems in reducing pathogenic density levels was evaluated according to the criteria established by the U.S. Environmental Protection Agency municipal sludge rule (40 CFR Part 503 Rule). In a year‐long effort, wastewater and biosolids samples were analyzed for both indicator and pathogenic organisms from different existing treatment systems. The results indicate that anaerobic digestion was superior to aerobic digestion in reducing pathogen density levels under the given field conditions. Composting was far more superior to both anaerobic and aerobic digestion. This study demonstrates that the Class B requirements under the 503 Rule are reasonable and can be achievable by most existing treatment systems, whereas the Class A requirements under the same rule may not be easily achieved by many existing treatment works. The effects of volatile solids loading rates on anaerobic and aerobic digester performance were investigated. Under anaerobic digestion conditions, the log reductions in fecal coliform and fecal streptococci appeared to be dependent on volatile suspended solids (VSS) loading rates. However, this trend was not evident in aerobic digestion systems sampled. Salmonella density reductions did not appear to be dependent on VSS loading rates in either case.
Estimation of Pulmonary Motion in Healthy Subjects and Patients with Intrathoracic Tumors Using 3D-Dynamic MRI: Initial Results (2009)

A 3D-dynamic MRI is able to quantify intraparenchymal lung motion. Local and global parenchymal pathologies can be precisely located and might be a new tool used to quantify even slight changes in lung motion (e.g. in therapy monitoring, follow-up studies or even benign lung diseases).
Service Value Aware Memory Scheduler by Estimating Request Weight and Using per-Thread Traffic Lights (2016)

HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci-entific research documents, whether they are pub-lished or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et a ̀ la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.
Luminescence Thermometry on the Route of the Mobile‐Based Internet of Things (IoT): How Smart QR Codes Make It Real (2019)

Quick Response (QR) codes are a gateway to the Internet of things (IoT) due to the growing use of smartphones/mobile devices and its properties like fast and easy reading, capacity to store more information than that found in conventional codes, and versatility associated to the rapid and simplified access to information. Challenges encompass the enhancement of storage capacity limits and the evolution to a smart label for mobile devices decryption applications. Organic-inorganic hybrids with europium (Eu<sup>3+</sup>) and terbium (Tb<sup>3+</sup>) ions are processed as luminescent QR codes that are able to simultaneously double the storage capacity and sense temperature in real time using a photo taken with the charge-coupled device of a smartphone. The methodology based on the intensity of the red and green pixels of the photo yields a maximum relative sensitivity and minimum temperature uncertainty of the QR code sensor (293 K) of 5.14% · K<sup>-1</sup> and 0.194 K, respectively. As an added benefit, the intriguing performance results from energy transfer involving the thermal coupling between the Tb<sup>3+</sup>-excited level (<sup>5</sup>D<sub>4</sub>) and the low-lying triplet states of organic ligands, being the first example of an intramolecular primary thermometer. A mobile app is developed to materialize the concept of temperature reading through luminescent QR codes.
Calcification of the Aortic Arch (2000)

In our population-based cohort, aortic arch calcification was independently related to coronary heart disease risk in both sexes as well as to ischemic stroke risk in women. JAMA. 2000;283:2810-2815
Promoter elements and factors involved in hepatic transcription of the human ApoA-I gene positive and negative regulators bind to overlapping sites. (1991)

DNase I footprinting analysis of the proximal apoA-I promoter sequences with rat liver nuclear extracts identified four protected regions: A, -22 to +17; B, -128 to -77; C, -175 to -148; and D, -220 to -190. Region D (-220 to -190) binds at least two distinct activities, designated AID1 and AID2, respectively, which can be separated by ion exchange chromatography. Region C (-175 to -148) forms five DNA protein complexes. Three of the complexes (2, 4, and 5) originate from the binding of more than one heat-stable nuclear factor, and two (1 and 3), from the binding of two heat-labile factors. The heat-stable factors bind in the -175 to -148 region and can be distinguished from C/EBP, which recognizes the same region, with DNA binding gel electrophoretic assays. Both factors 1 and 3 bind in the -168 to -148 apoA-I region. Despite the lack of a CCAAT motif in this region, the binding of factor 1 is competed out by oligonucleotides containing the binding sites of NFY and NFY*. Mutagenesis of the promoter region showed that mutations in the -171 to -166 and -158 to -153 regions diminished the binding of the heat-stable factors and reduced hepatic transcription to 14 and 8% of control, respectively. In contrast, a mutation in the -164 to -159 region abolished the binding of factor 1 and was associated with a 4.6-fold increase in hepatic transcription. These findings suggest that the heat-stable factors act as positive regulators, whereas factor 1 acts as a negative regulator in apoA-I gene transcription.
Continuous fractionation of used frying oil by supercritical CO<sub>2</sub> (2004)

Abstract Fractionation by supercritical carbon dioxide (SC−CO 2 ) might be a way to purify used frying oils, since a selective separation of the oil components based on their polarity and M.W. can be attained. In this work, we studied the purification of peanut oil used for frying by SC−CO 2 continuous fractionation in a packed column. The influence of pressure (15–35 MPa) and temperature (25–55°C) on the yield and on the composition of products was determined. The composition of the top and bottom products was evaluated by using size‐exclusion chromatography and other accepted chemical methods. Process conditions were selected to separate TG from degraded compounds. Experimental results indicated that the operating conditions leading to maximal TG recovery in the extract were 35 MPa, 55°C, and a solvent‐to‐feed ratio of 53. By operating at these conditions, it was possible to recover 97% of the TG placed on the column and about 52% by weight of the used frying oil. The composition of the purified top stream was very similar to that of fresh frying oil.
A new medical data management concept in a hybrid cellular mobile radio communication network (2002)

Patient data produced by different medical diagnostic image systems (modalities) are transferred into the medical information environment (MIE) and saved in common databases, by means of a PACS (picture archiving and communication system). Physicians handle the patient data on medical workstations, employing special displaying and processing techniques. The authors present a novel concept for the integration of patient data handling, using a prototype unified image viewing (UIV) scheme, applicable to a national wide-area communication network (NWCN). For this purpose, they investigate, study, and analyze a national-type cellular mobile communication network for UIV medical application, in regard to the increase in traffic capacity, by adopting a novel channel assignment strategy in conjunction with accepted digital transmission methods (data format-modulation and error control).< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
<i>Clostridium difficile</i>- Associated Diarrhea in a VA Medical Center Clustering of Cases, Association With Antibiotic Usage, and Impact on HIV-infected Patients (2001)

A case-control study of patients with stools assayed for Clostridium difficile toxin over a 24-month period at a Veterans Affairs hospital found that the majority of cases (70.6%) occurred in temporal clusters. Clustering was particularly evident on a designated human immunodeficiency virus (HIV) unit. Thirty-four (75.5%) of 45 HIV-infected patients with C difficile-associated diarrhea (CDAD) died during their hospitalization. Third-generation cephalosporins were the antibiotics most strongly associated with CDAD.
Fabrication of carbon nanotube/graphene core/shell nanostructures on SiO2 substrates using organic solvents: A molecular dynamics study (2012)

Using molecular mechanics and molecular dynamics simulations, we demonstrate that it is difficult to fabricate single-walled carbon nanotube (SWNT)/carbon nanoscroll (CNS) core/shell nanostructures on solid substrates because of the strong interaction between the graphene (GN) and the substrate. We propose an effective way to reduce the interaction between the GN and the substrate; SWNT/CNS core/shell nanostructures can be fabricated easily on SiO2 substrates by exploiting the volatilization of organic solvents, and inducement with SWNTs. These SWNT/CNS core/shell nanostructures on SiO2 substrates have the potential to be applied in telecom network transmission, or as electronic components in apparatuses such as microcircuit interconnects, nanoelectronics devices, heterojunctions, or sensors.
Using Virtual Reality and 360-degree Photos and Videos in Marketing (2018)

Virtual reality has been up and coming for years and there are a lot of possibilities for marketers. Still in year 2018 not many of the companies have invested into virtual reality or 360-degree photo/video marketing.\n\nThis thesis is all about the technologies and history behind virtual reality and how marketers could use virtual reality as their part of their marketing activities. It will tell you all the important numbers about virtual reality, what popular VR headsets there are and what kind of actions you can take to use virtual reality in your marketing.\n\nTravel industry is one of the industries which will benefit the most from virtual reality and 360-degree video/photos in their marketing since the visual content is extremely valuable in travel marketing. Virtual reality offers marketers new way to market locations and accommodation by sending them there, virtually and it creates possibilities for agencies, too. \n\nIt also offers new ways for more effective advertising since the users are completely immersed into the content. \n\nMany Real Estate businesses are already using VR since it allows them to showcase future projects that they haven’t even started building and gain revenue from early on. \n\nVirtual reality also offers a “WOW”-factor and companies like Lenovo are already using it in their trade shows successfully as the 350% increase of the leads shows. Companies can now invite all their peers around the world to their events by using livestreaming with virtual reality.
Type-II Restriction and Modification Enzymes (1982)

INTRODUCTION DNA restriction endonucleases and their companion modification methylases have been identified in a wide variety of prokaryotes (Roberts 1982). Three distinct classes of restriction-modification systems have been found that differ in their cofactor requirements. The type-I and type-III enzymes have rather specific cofactor requirements and have been studied in detail, both biochemically and genetically (see Chapter 5). Although they recognize specific sequences on DNA, they cleave randomly at sites remote from the recognition sequence and so do not produce specific fragments. In contrast, the type-II restriction enzymes require only Mg 2+ as a cofactor and they both recognize and cleave a specific sequence within the DNA molecule. It is this property that has rendered these enzymes so useful to the molecular biologists. Recombinant DNA technology and the present rapid methods for DNA sequence analysis are two important areas that have become possible because of the existence of these enzymes. As with their type-I and type-III counterparts, the biological phenomenon of restriction and modification can be catalyzed by the type-II enzymes. However, it is important to note that for the vast majority of these enzymes there is no genetic evidence showing that they are involved in host-controlled restriction-modification, and it is quite possible that some of them have other, as yet undiscovered, roles in the cell. Whereas interest in the type-I and type-III enzymes centers around their biological properties, this is not true of the type-II enzymes. In this case, interest has focused on their use as tools with which to...
Red light of the visual spectrum attenuates cell death in culture and retinal ganglion cell death <i>in situ</i> (2016)

Low, non-toxic levels of red light focussed on the retina for a short period of time are sufficient to attenuate an insult of raised IOP to the rat retina. Since mitochondrial dysfunctions are thought to play a major role in ganglion cell death in glaucoma, we propose the potential use of red light therapy for the treatment of the disease.
Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells (1994)

GATA-1 is an essential factor for the transcriptional activation of erythroid-specific genes, and is also abundantly expressed in a discrete subset of cells bordering the seminiferous epithelium in tubules of the murine testis. In examining normal and germ-line defective mutant mice, we show here that GATA-1 is expressed only in the Sertoli cell lineage in mouse testis. GATA-1 expression in Sertoli cells is induced concomitantly with the first wave of spermatogenesis, and GATA-1-positive cells are uniformly distributed among all tubules during prepubertal testis development. However, the number of GATA-1-positive cells declines thereafter and were found only in the peripheral zone of seminiferous tubules in stages VII, VIII and IX of spermatogenesis in the adult mouse testis. In contrast, virtually every Sertoli cell in mutant W/Wv, jsd/jsd or cryptorchid mice (all of which lack significant numbers of germ cells) expresses GATA-1, thus showing that the expression of this transcription factor is negatively controlled by the maturing germ cells. These observations suggest that transcription factor GATA-1 is a developmental stage- and spermatogenic cycle-specific regulator of gene expression in Sertoli cells.
Representing IPv6 Zone Identifiers in Address Literals and Uniform Resource Identifiers (2013)

This document describes how the zone identifier of an IPv6 scoped address, defined as <zone_id> in the IPv6 Scoped Address Architecture (RFC 4007), can be represented in a literal IPv6 address and in a Uniform Resource Identifier that includes such a literal address. It updates the URI Generic Syntax specification (RFC 3986) accordingly.
New Sulfonamides (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew SulfonamidesJ. M. Loynes, H. F. Ridley, and R. G. W. SpickettCite this: J. Med. Chem. 1965, 8, 5, 691–694Publication Date (Print):September 1, 1965Publication History Published online1 May 2002Published inissue 1 September 1965https://pubs.acs.org/doi/10.1021/jm00329a029https://doi.org/10.1021/jm00329a029research-articleACS PublicationsRequest reuse permissionsArticle Views223Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Treatment of Acute Antibody-Mediated Rejection in Kidney Transplant Recipients—A Systematic Review (2012)

Data describing the efficacy of treatments for AMR in renal allografts are of low or very low quality. Larger randomized controlled trials and dose-response studies are required.
Key Update Mechanism in PKI: Study and a New Approach (2013)

Public-Key Infrastructure (PKI) provides robust and scalable security services like authentication and non-repudiation using digital certificates. An efficient key management is necessary for a long term implementation of PKI. As a part of key management, key pair of all the entities within the PKI system is updated regularly to minimize overuse of keys and to comply with the organization's policies. In a hierarchical PKI system, root Certificate Authority (CA) is the highest trust anchor and hence updating its key pair is a challenging task. It requires proper authentication of certificate issuing entities to its subordinates and storage of keys for future reference. This paper discusses the various mechanisms available for updating root CA key pairs and brings out pros and cons in each. Considering the shortcomings of these methods, a new method for key pair update has been proposed, which is less complex and easy to implement. In addition, some of the open-source tools available to implement these techniques and open challenges which need to be addressed to have been highlighted.
Ginseng and male reproductive function (2013)

Ginseng is often referred to as the King of all herbs, and is found to be a promising agent to improve general well-being. Ginseng has also been reputed as an aphrodisiac, and is used to treat sexual dysfunction as well as to enhance sexual behavior in traditional Chinese medical practices. Data from animal studies have shown a positive correlation among ginseng, libido, and copulatory performances, and these effects have been confirmed in case-control studies in human. In addition, ginseng is found to improve the sperm quality and count of healthy individuals as well as patients with treatment-related infertility. These actions are mostly attributed to ginsenosides, the major pharmacological active components of ginseng. This review compiles the current knowledge about the multifaceted effects of ginseng on male reproductive function, and also focuses on its mechanisms of action that may represent novel therapeutic strategies for the treatment of male reproductive diseases or disorders.
Highly Enantioselective Synthesis of Chiral Secondary Amines by Gold(I)/Chiral Brønsted Acid Catalyzed Tandem Intermolecular Hydroamination and Transfer Hydrogenation Reactions (2009)

A method for the synthesis of enantiomerically enriched secondary amines with excellent ee values through the tandem intermolecular hydroamination/transfer hydrogenation of alkynes using a "gold(I) complex-chiral Brønsted acid" protocol is developed. The catalysis works for a wide variety of aryl, alkenyl, and aliphatic alkynes as well as anilines with different electronic properties.
The Structure of Anthracene (1936)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Structure of AnthraceneLouis F. Fieser and Warren C. LothropCite this: J. Am. Chem. Soc. 1936, 58, 5, 749–753Publication Date (Print):May 1, 1936Publication History Published online1 May 2002Published inissue 1 May 1936https://pubs.acs.org/doi/10.1021/ja01296a016https://doi.org/10.1021/ja01296a016research-articleACS PublicationsRequest reuse permissionsArticle Views510Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A Switching Estimated Receiver Position Scheme For Visible Light Based Indoor Positioning System (2009)

Indoor positioning system based on visible light communication (VLC) identifier (ID) and 6-axes sensor (geomagnetic sensor and gravity acceleration sensor) has higher accuracy than simple VLC-ID based positioning system. In this paper, we propose a switching estimated receiver position (SERP) scheme for the VLC-ID and 6-axes sensor based positioning system. The SERP improve the positioning accuracy by optimizing estimated error distance, which is varied in proportion to the receiver's tilt angle. We performed an experiment to confirm the improvement of SERP with three types of field of view (FOV) receivers. As a result, more than 30% improvement of accuracy is achieved comparing with the conventional position estimation scheme.