gebhart/patrepeval huggingface dataset:
Identification of a New Panel of Serum Autoantibodies Associated with the Presence of <i>In situ</i> Carcinoma of the Breast in Younger Women (2009)

This autoantibody assay against a panel of five antigens allows for an accurate discrimination between early-stage breast cancer, especially CIS, and healthy individuals. These results could be of interest in detecting early breast cancer as an aid to mammography, especially in women under the age of 50 years with aggressive cancers.
Advanced channel engineering achieving aggressive reduction of V<inf>T</inf> variation for ultra-low-power applications (2011)

We have achieved aggressive reduction of V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</inf> variation and V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DD-min</inf> by a sophisticated planar bulk MOSFET named ‘Deeply Depleted Channel ™ (DDC)’. The DDC transistor has been successfully integrated into an existing 65nm CMOS platform by combining layered channel formation and low temperature processing. The 2x reduction of V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</inf> variation in 65nm-node has been demonstrated by matching SRAM pair transistors, 2x improvement in SRAM static noise margin (SNM) and 300 mV V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DD-min</inf> reduction of 576Kb SRAM macros to 0.425 V using conventional 6T cell layout.
Comparison of the sequences of class A beta-lactamases and of the secondary structure elements of penicillin-recognizing proteins (1991)

The sequences of class A beta-lactamases were compared. Four main groups of enzymes were distinguished: those from the gram-negative organisms and bacilli and two distinct groups of Streptomyces spp. The Staphylococcus aureus PC1 enzyme, although somewhat closer to the enzyme from the Bacillus group, did not belong to any of the groups of beta-lactamases. The similarities between the secondary structure elements of these enzymes and those of the class C beta-lactamases and of the Streptomyces sp. strain R61 DD-peptidase were also analyzed and tentatively extended to the class D beta-lactamases. A unified nomenclature of secondary structure elements is proposed for all the penicillin-recognizing enzymes.
Resorbable materials of poly(<scp>L</scp>‐lactide). II. Fibers spun from solutions of poly(<scp>L</scp>‐lactide) in good solvents (1983)

Abstract Fibers of poly( L ‐lactide) (PLLA) with a tensile strength up to 1.2 GPa and Young's modulus in the range of 12–15 GPA were obtained by a hot drawing of fibers spun from solution of PLLA in good solvents such as dichloromethane and trichloromethane. The tensile strength of fibers was strongly dependent on the molecular weight of PLLA and on polymer concentrations in the spinning solution. Changing of the polymer concentration in the spinning solution gives rise to formation of fibers with different shape and porosity. Fibers spun from 10–20% solutions at room temperature exhibit a regular structurization, due to the melt fracture. These fibers had knot strengths up to 0.6 GPa, whereas fibers with a smooth surface spun from more dilute solutions had weaker square knots up to 0.3 GPa.
Salivary Gland Hyperglycemic Factor: An Extrapancreatic Source of Glucagon-Like Material (1977)

Extracts of homogenates of rat, mouse, rabbit, and human submaxillary salivary glands contain a significant quantity of a material with glucagon-like immunoreactivity. Fractionation of this material on columns of Sephadex G-100 reveals a single peak immediately following a gamma globulin marker but in advance of a rat growth hormone marker, crystalline amylase, and isotopically labeled porcine insulin and glucagon. This material, which is urea stable, shows identical immunoassay dilution curves when measured with the highly specific K-30 glucagon antiserum. Study of paired glands in vitro shows that low concentrations of glucose stimulate and high concentrations of glucose suppress release of this material. Arginine promotes brisk release in vitro. Somatostatin does not influence arginine-stimulated secretion and insignificantly suppresses basal release in vitro. These findings lend support to previous speculations that the salivary glands may possess endocrine as well as exocrine functions. Salivary gland glucagon may also be the source of circulating glucagon recently reported in pancreatectomized and eviscerated rats.
Design and validation of the transparent oxygen sensor array (1991)

A new oxygen monitoring system has been developed that consists of an array of transparent, independently-connected oxygen sensors mounted on a glass plate. This system is intended for continuous monitoring of oxygen at multiple locations on the surface of exteriorized tissues, while simultaneously visualizing microvascular activity. The sensor array is fabricated by techniques similar to those employed for semiconductors, which facilitate customization of sensor size and pattern to best monitor oxygen in a given physiologic preparation. Methods are described for characterizing the performance of the sensor array in vitro, including studies on the oxygen sensitivity, stability of the signal, and detection of oxygen gradients. An example of in vivo application of the sensor array is also presented.
Mitochondrial Transcription Factor A in the Maintenance of Mitochondrial DNA (2005)

Mitochondria have their own genome, which is essential for proper oxidative phosphorylation needed for a large part of ATP production in a cell. Although mitochondrial DNA-less (rho0) cells can survive under special conditions, the integrity of the mitochondrial genome is critical for survival of multicellular organisms. Mitochondrial transcription factor A (TFAM), originally cloned as transcription factor, is essential for the maintenance of mtDNA. Recently, it has become known that TFAM plays critical roles in multiple aspects to maintain the integrity of mitochondrial DNA: transcription, replication, nucleoid formation, damage sensing, and DNA repair. The effects of TFAM in these aspects are intimately related to each other and to function as a whole for the purpose of maintenance of mtDNA.
ADDICTION PROBLEMS IN THE WORKPLACE: PROGRAMMES AND STRATEGIES (1991)

Outlines German experience of dealing with workplace alcoholism by a preventive approach. Programmes are usually companybased, have defined aims relating to public relations, motivation of staff and development and implementation of assistance to employees with dependence problems. Programming may involve individuals or groups (sometimes study groups). Opposition by superiors and a company culture with a positive attitude to alcohol are the major problems. Programmes must be long‐term and ways of developing them in response to change are outlined.
Spherical Model of an Acoustical Wave Generated by Rapid Laser Heating in a Liquid (1969)

A spherical model for the acoustic pressure-wave generated by the rapid thermal expansion owing to laser heating is analytically investigated. The physics of the wave generation is extensively discussed, and from this point of view the mathematical boundary value problem is formulated. A Laplace-transform-Green-function method is applied to solve this problem, and the resultant pressure wave is expressed as a function of time, space, and input parameters. The result shows that any point in the medium outside the laser focus experiences, first, a strong positive pressure pulse, and then, a strong tension (negative pressure) pulse. The shape of these two pulses is skew symmetric with respect to the central time between the two peaks of the pulses. These two peaks occur respectively at the retarded starting and extinguishing edges of the laser pulse. The magnitudes of these two peaks are equal. They are proportional to the laser intensity, and inversely proportional to the distance of observation. Numerical examples are given.
CD69 Limits the Severity of Cardiomyopathy After Autoimmune Myocarditis (2010)

Our findings indicate that CD69 negatively regulates heart-specific Th17 responses, cardiac inflammation, and heart failure progression in EAM.
IP geolocation databases (2011)

The most widely used technique for IP geolocation consists in building a database to keep the mapping between IP blocks and a geographic location. Several databases are available and are frequently used by many services and web sites in the Internet. Contrary to widespread belief, geolocation databases are far from being as reliable as they claim. In this paper, we conduct a comparison of several current geolocation databases -both commercial and free- to have an insight of the limitations in their usability. First, the vast majority of entries in the databases refer only to a few popular countries (e.g., U.S.). This creates an imbalance in the representation of countries across the IP blocks of the databases. Second, these entries do not reflect the original allocation of IP blocks, nor BGP announcements. In addition, we quantify the accuracy of geolocation databases on a large European ISP based on ground truth information. This is the first study using a ground truth showing that the overly fine granularity of database entries makes their accuracy worse, not better. Geolocation databases can claim country-level accuracy, but certainly not city-level.
Prenatal Diagnosis of Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency (1977)

There is a paucity of data concerning the feasibility of the early antenatal diagnosis of congenital adrenal hyperplasia (CAH). Jeffcoate et al.1 reported elevated amniotic fluid 17-keto-steroid and pregnanetriol levels in a patient at term carrying a fetus with CAH. Nichols2 and Nichols and Gibson3 reported high amniotic fluid pregnanetriol levels in two other patients in term pregnancies. In contrast, Merkatz et al.4 found normal amniotic fluid 17-ketosteroid and pregna-netriol levels in two other patients carrying fetuses with CAH who had repeated amniocenteses at 26, 30, 35, 38, and 33 and 37 weeks gestation. New5 also noted that in his experience, 17-ketosteroid or pregnanetriol levels in amniotic fluid were not useful for the antenatal diagnosis of CAH.
Vitreous Hemorrhage as the Presenting Ocular Feature of Choroid Metastasis from Lung Cancer: A Case Report (2014)

Purpose: To report a case of choroidal metastasis from lung cancer with vitreous hemorrhage as the presenting ocular feature. Methods: A case report. Result: A 51-year-old female with a history of lung cancer was referred to our hospital because of sudden-onset visual field defect and blurred vision in the left eye experienced for one day. The best corrected visual acuity of her left eye was counting fingers at 25 cm. Ocular examination results were normal except for vitreous hemorrhage and a yellowish elevated mass at the left eye's superonasal quadrant fundus. B-scanning of the left eye demonstrated a dome-surfaced, elevated choroidal lesion with moderated internal reflectivity. Orbital magnetic resonance imaging (MRI) revealed a rounded lesion in the left eyeball that was 5.2 mm in vertical length, 4.6 mm in height and 7.5 mm in horizontal length. Lung cancer with choroidal metastasis was highly suspected. Because the patient refused radiotherapy, a 23-gauge pars plana vitrectomy (PPVT) and intravitreal bevacizumab injection were performed. At follow-up, the best corrected visual acuity (BCVA) had improved and the size of the choroidal mass had regressed. Conclusion: Although it is rare, vitreous hemorrhage can be the presenting ocular feature of choroidal metastasis from lung cancer. For patients with a diagnosis of vitreous hemorrhage from choroidal metastasis who refuse radio-therapy, vitrectomy with intravitreal bevacizumab may be a choice to improve quality of life.
Studies on Tannins of Fruits and Vegetables (1972)

In previous reports, it has been shown that all soluble tannin removal agents, methyl cellulose, polyethers, and soluble polyvinyl pyrrolidone were able to precipitate high molecular tannin but not low molecular polyphenolics. But, inversely, insoluble polyvinylpyrrolidone (PVPi, Polyclar AT) largely adsorbs low molecular polyphenolics, such as catechins, anthocyanins, naringin etc., and the larger the molecular weight of tannin, the smaller the adsorption. Adsorption of catechin and tannic acid is scarcely affected by pH, and that of anthocyanin decreases under pH of 5. The temperature of maximum adsorption of catechin and anthocyanin is 50° and 30° respectively. But tannic acid is greatly adsorbed over 50°. The effects of the coexistence of sucrose, Na2SO4, and ethanol are also different according to the size of molecule of polyphenolics. When juices of strawberry and grape were treated with PVPi, juices were practically decolourized as a result of the removal of anthocyanin. When the extracts of grape, loquat, and tea were treated, most of tannin and little of chlorogenic acid remaind. It is, therefore, concluded that PVPi would be utilized for removal of low molecular polyphenolics and stabilization of beverages.
Traumatic brain injury and recovery mechanisms: peptide modulation of periventricular neurogenic regions by the choroid plexus–CSF nexus (2010)

In traumatic brain injury (TBI), severe disruptions occur in the choroid plexus (CP)-cerebrospinal fluid (CSF) nexus that destabilize the nearby hippocampal and subventricular neurogenic regions. Following invasive and non-invasive injuries to cortex, several adverse sequelae harm the brain interior: (i) structural damage to CP epithelium that opens the blood-CSF barrier (BCSFB) to protein, (ii) altered CSF dynamics and intracranial pressure (ICP), (iii) augmentation of leukocyte traffic across CP into the CSF-brain, (iv) reduction in CSF sink action and clearance of debris from ventricles, and (v) less efficient provision of micronutritional and hormonal support for the CNS. However, gradual post-TBI restitution of the injured CP epithelium and ependyma, and CSF homeostatic mechanisms, help to restore subventricular/subgranular neurogenesis and the cognitive abilities diminished by CNS damage. Recovery from TBI is facilitated by upregulated choroidal/ependymal growth factors and neurotrophins, and their secretion into ventricular CSF. There, by an endocrine-like mechanism, CSF bulk flow convects the neuropeptides to target cells in injured cortex for aiding repair processes; and to neurogenic niches for enhancing conversion of stem cells to new neurons. In the recovery from TBI and associated ischemia, the modulating neuropeptides include FGF2, EGF, VEGF, NGF, IGF, GDNF, BDNF, and PACAP. Homeostatic correction of TBI-induced neuropathology can be accelerated or amplified by exogenously boosting the CSF concentration of these growth factors and neurotrophins. Such intraventricular supplementation via the CSF route promotes neural restoration through enhanced neurogenesis, angiogenesis, and neuroprotective effects. CSF translational research presents opportunities that involve CP and ependymal manipulations to expedite recovery from TBI.
Oral Gabapentin Activates Spinal Cholinergic Circuits to Reduce Hypersensitivity after Peripheral Nerve Injury and Interacts Synergistically with Oral Donepezil (2007)

Although gabapentin may relieve neuropathic pain by actions at many sites, these results suggest that its actions in the brain to cause spinal cholinergic activation predominate after oral administration. Side effects, particularly nausea, cannot be accurately determined on rats. Nevertheless, oral donepezil is well tolerated by patients in the treatment of Alzheimer dementia, and the current study provides the rationale for clinical study of combination of gabapentin and donepezil to treat neuropathic pain.
Interstitial hyperthermia of colorectal liver metastases with a US-guided Nd-YAG laser with a diffuser tip: a pilot clinical study. (1993)

Ultrasound (US)-guided interstitial hyperthermia performed with the neodymium yttrium aluminum garnet laser with a diffuser tip involves placement of a laser fiber in solid tissue followed by irradiation from within the center of the tumor to be treated. The authors previously described the development of a US-guided technique that permits simultaneous interstitial laser irradiation and temperature measurements, with real-time US monitoring. With the use of a dedicated diffuser tip modification of the bare laser fiber, it has proved possible to produce spherical coagulations with a diameter comparable to that of liver metastases of clinical relevance. This technique was used in 11 patients with 16 colorectal liver metastases, 12 of which were radically ablated. Real-time US and interstitial temperature monitoring during treatment had a positive predictive value of 86% and negative predictive value of 100% in judging the final result. The technique is feasible, effective, and safe, but the effect on patient survival must be tested in future randomized clinical studies.
SYSTEMS OF FREQUENCY CURVES GENERATED BY METHODS OF TRANSLATION (1949)

Journal Article SYSTEMS OF FREQUENCY CURVES GENERATED BY METHODS OF TRANSLATION Get access N. L. JOHNSON N. L. JOHNSON Search for other works by this author on: Oxford Academic Google Scholar Biometrika, Volume 36, Issue 1-2, June 1949, Pages 149–176, https://doi.org/10.1093/biomet/36.1-2.149 Published: 01 June 1949
Processing techniques for surface surveillance radars in littoral environments (2002)

Processing techniques specifically designed for the detection of surface vehicles of all sizes in the presence of all types of clutter are described. The techniques described consist of a range adaptive motion compensated digital moving target detector followed by adaptive thresholding techniques.
Structure/Volatility Correlation of Sodium and Zirconium Fluoroalkoxides (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure/Volatility Correlation of Sodium and Zirconium FluoroalkoxidesJohn A. Samuels, Kirsten Folting, John C. Huffman, and Kenneth G. CaultonCite this: Chem. Mater. 1995, 7, 5, 929–935Publication Date (Print):May 1, 1995Publication History Published online1 May 2002Published inissue 1 May 1995https://pubs.acs.org/doi/10.1021/cm00053a018https://doi.org/10.1021/cm00053a018research-articleACS PublicationsRequest reuse permissionsArticle Views289Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (3)»Supporting Information Supporting Information Get e-Alerts
Vitreoretinal Surgical Techniques, Second Edition (2001)

1. Surgical Techniques for the Treatment of Retinal Tears and Complicated Retinal Detachment 2. Visualization Techniques During Vitrectomy 3. Techniques of Pars Plana Vitrectomy 4. Surgical Techniques for the Management of Complications of Cataract Surgery 5. Surgical Techniques in Diabetic Retinopathy 6. Surgical Techniques in Proliferative Vitreoretinopathy and Macular Hole Surgery 7. Subretinal Surgery Techniques 8. Surgical Techniques of Posterior Segment Tumors 9. Surgical Techniques in Trauma 10. Management of Endophthalmitis 11. Pediatric Vitreoretinal Surgery 12. Surgical Techniques in Viral Retinitis 13. Latest Surgical Techniques
Photonics and electronics integration in the HELIOS project (2010)

The objective of the European project HELIOS is to combine a photonic layer with a CMOS circuit by different innovative means, using microelectronics processes. Bonding of AWG + Ge Photodiodes on CMOS wafer is achieved.
Effect of Yellow-Interval Timing on the Frequency of Red-Light Violations at Urban Intersections (2004)

Statistics indicate that red-light running has become a significant safety problem throughout the United States. There is a wide range of potential countermeasures to the problem of red-light running; an increase in yellow duration is one countermeasure. The objective of this research was to quantify the effect of a change in yellow-interval duration on the frequency of red-light violations. A before-after study is described and the resulting data are used to quantify the effect of increasing the yellow interval on the frequency of red-light violations. Based on this research, it was concluded that ( a) an increase of 1.0 s in yellow duration (such that it does not exceed 5.5 s) will decrease the frequency of red-light violations by at least 50%; ( b) drivers do adapt to the increase in yellow duration, but this adaptation does not undo the benefit of an increase in yellow duration; and ( c) increasing a yellow interval that is shorter than the value obtained from a proposed recommended equation published by the Institute of Transportation Engineers is likely to yield the greatest return (in terms of a reduced number of red-light violations) relative to the cost of retiming a yellow interval in the field.
Helium speech enhancement by frequency-domain processing (2005)

The breathing gas of divers is a pressurized mixture of helium and oxygen that distorts the divers' speech. The formant frequencies and bandwidths shift upward in a nonlinear manner while the pitch period remains relatively unchanged. Commercial unscramblers (voice enhancers) work in the time domain, sampling segments of diver speech and expanding them. This technique does enhance diver speech, but not enough for reliable communication. We have implemented an algorithm that operates in the frequency domain and runs in real time on an Analogic AP400 array processor. The algorithm transforms helium speech segments into the frequency domain, compresses the formants back to normal speech values, and then transforms the corrected speech segments back into the time domain. Identical speech material was processed by both the time- and frequency-domain unscramblers and the results are compared.
The Development of a Radiation Hardened Polymer Dielectric by Chemical Doping (1983)

X-ray induced photoconductivity measurements reveal that the radiation-induced conductivity of polyethylene terepthalate films is greatly reduced by doping this polymer with 2,4,6-trinitrofluorenone which acts as a deep trap for the photocarriers. The radiation-induced conductivity of this doped dielectric is reduced to 1 percent of the value for the undoped material and is lower than that observed in commercial polymer films we have studied. The preparation and dielectric properties of the doped films are described.
Joggobot (2012)

Exertion activities, such as jogging, provide many health benefits, but exercising on your own can be considered disengaging. We present our system 'Joggobot', a flying robot accompanying joggers. Our design process revealed preliminary insights into how to design robots for exertion and how to address emerging design challenges. We summarize these insights into the four themes: 'embodiment', 'control', 'personality' and 'communication', which mark initial starting points towards understanding how to design robots for exertion activities. We hope our work guides and inspires designers when facilitating the benefits of exertion through robots.