gebhart/patrepeval huggingface dataset:
3-inch GaN-on-Diamond HEMTs With Device-First Transfer Technology (2017)

Based on a device-first transfer process, a 3-inch polycrystalline diamond substrate is bonded within 1.5 μm of the junction in GaN high electron mobility transistors (HEMTs) to enhance heat removal of the high-power RF devices. Highly preserved electrical performance is demonstrated by comparison exactly on the same HEMT device prior and after substrate transfer. The residual compressive strain relaxation of the whole GaN epilayer does not reduce the 2-D electron gas sheet density. The dc characteristics show weakened self-heating in the GaN-on-diamond HEMT with maximum current density increasing from 968 to 1005 mA/mm. The power density increases from 4.8 to 5.5 W/mm with the PAE slightly reducing from 50.9% to 50.5%. On-wafer infrared measurement is performed on a 1.25-mm GaN HEMT at power dissipation of 10 W/mm, and the peak juncture temperature of the device decreases from 241 °C to 191 °C after transferring to the diamond substrate.
Translocation of Hormone-sensitive Lipase and Perilipin upon Lipolytic Stimulation of Rat Adipocytes (2000)

Adipocyte lipolysis was compared with hormone-sensitive lipase (HSL)/perilipin subcellular distribution and perilipin phosphorylation using Western blot analysis. Under basal conditions, HSL resided predominantly in the cytosol and unphosphorylated perilipin upon the lipid droplet. Upon lipolytic stimulation of adipocytes isolated from young rats with the beta-adrenergic agonist, isoproterenol, HSL translocated from the cytosol to the lipid droplet, but there was no movement of perilipin from the droplet to the cytosol; however, perilipin phosphorylation was observed. By contrast, upon lipolytic stimulation and perilipin phosphorylation in cells from more mature rats, there was no HSL translocation but a significant movement of perilipin away from the lipid droplet. Adipocytes from younger rats had markedly greater rates of lipolysis than those from the older rats. Thus high rates of lipolysis require translocation of HSL to the lipid droplet and translocation of HSL and perilipin can occur independently of each other. A loss of the ability to translocate HSL to the lipid droplet probably contributes to the diminished lipolytic response to catecholamines with age.
The Trial of Conrad Murray: Prosecuting Physicians for Criminally Negligent Over-Prescription (2014)

On June 25, 2009, Michael Jackson died in his sleep from cardiac arrest, sending shockwaves throughout the public sphere. Popular response to his untimely demise was staggering. In the days following initial reports of his death, fans flooded the Internet with an unprecedented number of searches, comments, and messages. Grieving admirers held memorial services across the globe, and even the President of the United States sent his condolences. News about Jackson dominated the airwaves for weeks, erasing any doubt that the “King of Pop” had been one of the most entertaining and controversial cultural icons in modern history. Over a legendary music career spanning four decades, Jackson treated audiences to electrifying stage performances and multi-platinum albums, including Thriller, the top-selling album of all time. However, in later years he achieved equal infamy for his ever-changing physical appearance, ostentatious personal life, and eccentric habits. One of Jackson’s most notorious vices was an addiction to prescription medication. The latter half of his career featured lurid accounts of his
Strategies for the development of vaccines against HIV (1989)

Possible approaches to the development of vaccines against HIV are reviewed in the light of experience with existing virus vaccines and understanding of the process of viral infection. While HIV infection presents serious theoretical problems in developing vaccines most are also encountered in some form with other virus infections. The very nature of HIV infection raises objections to using live attenuated or inactivated virus vaccines, as it is difficult to ensure that they are non-infectious or completely inactivated. The most promising types of vaccine involve expression of viral antigens in acceptable vectors either as virus vectors, or recombinant DNA products. However, the problem of identifying the antigen needed to induce adequate protective immunity remains and there is a clear need for a usable animal model to establish the potential of vaccines for human use.
Slip generation during rapid thermal processing (1996)

The generation of slip in 100 mm (100) silicon wafers during rapid thermal oxidation is investigated in dependence on process temperature, process duration, and heating rate. The processes were carried out in a scalar controlled RTP equipment with three-zone rotation-symmetrical illumination. The wafer temperature was measured in three points (centre, edge, half distance between both) by thermopiles during the whole process. In addition, the oxidation temperature was monitored. X-ray topography investigations show that slip lines are generated at process temperatures higher than 1050 °C, that the length of the slip lines increases with higher process temperature and reaches a saturation value for long process times. The experiments and the simulations provided that for ramp rates ≤200 K/s slip dislocation lines are formed during the processing period of constant temperature.
Retrospective assessment of prevalence of nephrogenic systemic fibrosis (NSF) after implementation of a new guideline for the use of gadobenate dimeglumine as a sole contrast agent for magnetic resonance examination in renally impaired patients (2009)

From May 2007 to January 2008, patients with Stage 3-5 chronic kidney disease (CKD) undergoing gadobenate dimeglumine (GBD)-enhanced magnetic resonance (MR) examinations were included in the retrospective investigation. The electronic medical records were reviewed to assess the prevalence of nephrogenic systemic fibrosis (NSF) in renally impaired patients underwent GBD-enhanced MR examinations. In all, 250 patients (98 men, mean age 72.6 years) were included: 97% of the patients had Stage 3 CKD (estimated GFR 30-59 mL/min/1.73 m(2)); 37% had been exclusively exposed to GBD. The remaining were exposed to GBD and other gadolinium-based contrast agents (GBCAs). The mean dose of GBD was 22 mL (standard deviation [SD], 11.2). Including exposure to other GBCAs, the mean cumulative dose of gadolinium was 61 mL (SD, 62.3). A total of 206 patients (82%) had skin examinations following the last GBD administration (mean duration, 108 days). No evidence of suspected or diagnosed NSF was found. In conclusion, on the basis of a retrospective chart review there was no skin evidence of NSF in predominantly Stage 3 CKD patients who were exposed to GBD at an average follow-up of 108 days, either solely or in combination with other GBCAs. J. Magn. Reson. Imaging 2009;30:1335-1340. (c) 2009 Wiley-Liss, Inc.
Towards wearable capacitive sensing of physiological parameters (2008)

We describe an initial investigation of the suitability of body worn capacitive sensors for the measurement of physiological parameters. We describe the basic principle, our measurement setup, and initial signal examples obtained using a conductive textile electrode. The examples show that breathing, breathing depth, and even drinking a cup of water produce distinguishable signals.
Links between CD147 Function, Glycosylation, and Caveolin-1 (2004)

Cell surface CD147 shows remarkable variations in size (31-65 kDa) because of heterogeneous N-glycosylation, with the most highly glycosylated forms functioning to induce matrix metalloproteinase (MMP) production. Here we show that all three CD147 N-glycosylation sites make similar contributions to both high and low glycoforms (HG- and LG-CD147). l-Phytohemagglutinin lectin binding and swainsonine inhibition experiments indicated that HG-CD147 contains N-acetylglucosaminyltransferase V-catalyzed, beta1,6-branched, polylactosamine-type sugars, which account for its excess size. Therefore, CD147, which is itself elevated on invasive tumor cells, may make a major contribution to the abundance of beta1,6-branched polylactosamine sugars that appear on invasive tumor cells. It was shown previously that caveolin-1 associates with CD147, thus inhibiting CD147 self-aggregation and MMP induction; now we show that caveolin-1 associates with LG-CD147 and restricts the biosynthetic conversion of LG-CD147 to HG-CD147. In addition, HG-CD147 (but not LG-CD147) was preferentially captured as a multimer after treatment of cells with a homobifunctional cross-linking agent and was exclusively recognized by monoclonal antibody AAA6, a reagent that selectively recognizes self-associated CD147 and inhibits CD147-mediated MMP induction. In conclusion, we have 1) determined the biochemical basis for the unusual size variation in CD147, 2) established that CD147 is a major carrier of beta1,6-branched polylactosamine sugars on tumor cells, and 3) determined that caveolin-1 can inhibit the conversion of LG-CD147 to HG-CD147. Because it is HG-CD147 that self-aggregates and stimulates MMP induction, we now have a mechanism to explain how caveolin-1 inhibits these processes. These results help explain the previously established tumor suppressor functions of caveolin-1.
Role of Txk, a Member of the Tec Family of Tyrosine Kinases, in Immune-Inflammatory Diseases (2007)

Txk/Rlk, a member of the Tec family of tyrosine kinases, is an important signaling mediator. We previously reported that human Txk is expressed in Th1/Th0 cells, and Txk translocates from cytoplasm into nuclei upon activation. Txk regulates specifically interferon-gamma gene transcription. Txk, poly(ADP-ribose) polymerase 1, and elongation factor 1alpha make a complex to bind to interferon-gamma gene promoter region-53/-39 (Txk responsive element) to exert positive effects on transcription as a Th1 cell-associated transcription factor. Txk expression is enhanced in rheumatoid arthritis and Behçet's disease, where Th1 dominant immunity occurs. In bronchial asthma and atopic dermatitis, typical Th2 diseases, Txk expression is reduced. Modulation of Txk expression by gene transfer or similar modality may lead to the correction of aberrant immunity and, consequently, disease treatment.
Frequent pattern using Multiple Attribute Value for itemset generation (2011)

Data mining is the process of finding correlations or patterns among dozens of fields in large relational databases. While Association Rules Mining (ARM) algorithm especially the Apriori algorithm has been an active research work in recent years. Diverse improvement varies in term of producing more frequent items and also generating further k-length. The idea is to produce better pattern and more interesting rules. In this paper, we propose new approach for ARM based on Multiple Attribute Value within the non-binary search spaces. The proposed algorithm improves the existing frequent pattern mining by generating the most frequent values (item) within the attribute and generate candidate based on the frequent attribute value. The main idea of our work is to discover more meaningful frequent items and maximum k-length items. The experimental results show that our proposed MAV frequent pattern mining enhance the impact in generating more frequents items and maximum length.
Building information modeling (BIM) approach to the GMT Project (2014)

The Giant Magellan Telescope (GMT), one of several next generation Extremely Large Telescopes (ELTs), is a 25.4 meter diameter altitude over azimuth design set to be built at the summit of Cerro Campánas at the Las Campánas Observatory in Chile. The paper describes the use of Building Information Modeling (BIM) for the GMT project.
Horseradish Peroxidase Isozyme C: A Comparative Study of Native and Recombinant Enzyme Produced by <i>E. coli</i> Transformants<i><sup>a</sup></i> (1994)

The purification and refolding of the recombinant horseradish peroxidase produce by E. coli transformants are described. The recombinant enzyme is of 34 kDa and has an isozyme spectrum similar to Sigma type VI horseradish peroxidase. The specific activity of the refolded peroxidase is of about 2000 U/mg with ABTS as a substrate. The recombinant and native enzyme are similar with respect to their catalytic properties in the reaction of enhanced chemiluminescence. Operational and thermal stability of the refolded peroxidase is two to three times lower than for the native one.
Stimulated echo diffusion weighted imaging of the liver at 3 Tesla (2016)

The results verified the Δ dependence in diffusion measurements, indicating restricted diffusion in healthy human livers for the first time at 3T. This prepared STEAM DWI a potential technique for liver fibrotic studies in clinical practice. Magn Reson Med 77:300-309, 2017. © 2016 Wiley Periodicals, Inc.
Syntheses, Characterizations, and a Preliminary Comparative Cytotoxicity Study of Gold(I) and Gold(III) Complexes Bearing Benzimidazole- and Pyrazole-Derived N-Heterocyclic Carbenes (2012)

10.1021/om300444c
A Highly Parallel Sub-Pel Accurate Motion Estimator for H.264 (2006)

This paper presents a new H.264 motion estimation algorithm and architecture for video encoding. The algorithm resolves the sequential data dependencies of H.264 motion estimation by a new method, called "staggered approach". It adapts existing motion search methods (3DRS, hierarchical full search), maximizing parallel execution and allowing efficient pipelined execution while maintaining the high compression rate of H.264. Its regular and reduced-computation processing scheme makes the algorithm particularly suitable for high-performance hardware implementations, as required for realtime encoding of HDTV. The proposed motion estimator architecture demonstrates the suitability of the algorithm for cost-efficient consumer HDTV encoder chips
Serum Antibodies to Blood Group A Predict Survival on PROSTVAC-VF (2013)

In addition to reporting a new potentially predictive biomarker for PROSTVAC-VF, this study highlights the use of glycan microarray technology for improving our understanding of vaccine immunology. Clin Cancer Res; 19(5); 1290-9. ©2012 AACR.
An integrative approach to characterize disease-specific pathways and their coordination: a case study in cancer (2008)

Using a network-based approach, our method provides new insights into the complex cellular mechanisms that characterize cancer and cancer subtypes. By incorporating co-expression dynamics information, our approach can not only extract more functionally homogeneous modules than those based solely on network topology, but also reveal pathway coordination beyond co-expression.
Characterization of glomerular epithelial cell matrix receptors. (1992)

Integrin matrix receptors on glomerular epithelial cells (GEC) may play an important role in adhesion of GEC to the glomerular basement membrane (GBM) and in the maintenance of normal glomerular permeability. Therefore, the author determined the types of matrix receptors present on cultured rat GEC and examined their interactions with several components of the extracellular matrix. Beta 1 integrin matrix receptors were detected on all three glomerular cell types in rat kidney in vivo and at areas of cell-cell contact on cultured GEC. Glomerular epithelial cell adhesion to types I and IV collagen was slightly greater than to laminin and fibronectin. Adhesion to fibronectin was significantly inhibited by a synthetic peptide containing the RGD adhesion sequence. Immunoprecipitation of lysates of surface-iodinated GEC showed the presence of alpha 3 beta 1 integrin. Chromatography of lysates on immobilized collagen showed alpha 3 beta 1 integrin and a 70- to 75-kd protein band as the collagen receptors on GEC. Chromatography on the 120-kd cell-binding fragment of fibronectin disclosed only alpha 3 beta 1 as a specific fibronectin receptor. Antibody to the beta 1 integrin chain inhibited adhesion to laminin and collagen. These studies demonstrate that in vitro, as in vivo, GEC appear to express only alpha 3 beta 1 integrin. Furthermore, this matrix receptor is capable of mediating GEC adhesion to collagen, fibronectin, and laminin, components of the GBM, and presumably plays a similar role in promoting GEC adhesion to GBM in vivo.
Structural Characterization of Nanosheet-type MFI Zeolite (2011)

Zeolites are microporous crystalline aluminosilicates and have ordered micropores of a few Å in the structure. Zeolites are widely used in petrochemistry and fine-chemical synthesis because strong acid sites within their uniform micropores enable size- and shape-selective catalysis. Here we show that appropriately designed bifunctional surfactants can direct the formation of zeolite structures on the mesoporous and microporous length scales simultaneously, and thus produce nanosheet-type MFI zeolite that are only 2 nm thick, which corresponds to the b-axis dimension of a single MFI unit cell. The nanosheet-type MFI zeolite showd a significantly increased surface area, high catalytic activities, and excellent thermal and hydrothermal stability.
Boe: Context-Aware Global Power Management for Mobile Devices Balancing Battery Outage and User Experience (2014)

Energy conservation on mobile devices is now more important than ever due to the increasing benefits that smartphones and tablets provide to our daily life. However, most existing power management approaches either focus narrowly on a particular sub-system of the mobile device such as the sensor system, the LCD display, or the communication system, or use heuristic approaches to maximize energy efficiency at the cost of user experience. In this paper, we present Boe, a context-aware global power management scheme for mobile devices Balancing battery outage and user experience. To meet the mobile device's expected battery life while sacrificing end user experience as little as possible. Boe takes into account the users' phone usage patterns and activities to dynamically adjust the device's global power management policy to minimize outage time and maximize user experience. We demonstrate our proposed technique by controlling display brightness level and GPS sampling rate on smartphones. We evaluate our approach through real world smartphone data from 10 users over two months. Compared to the best fixed user experience policies, we show that: (i) Boe eliminates all frustrating battery outage events for light, moderate, and heavy phone users, and (ii) Boe improves user experience by 20% for light users, maintains the same user experience for moderate users, and degrades user experience by 23% for heavy smartphone users.
Polysiloxane deactivated fused silica capillaries containing immobilized stationary phases (1982)

Abstract This article describes a method of preparing immobilized stationary phases which has arisen from the authors' work on polysiloxane deactivation of fused silica capillaries. Although acid treatment is often omitted with fused silica capillaries, there are good reasons for hydrothermal treatment of this column material. Use of Grob 's peroxide method gave immobilized 0.25 μm films of SE‐54; lowering of the immobilization temperature permitted immobilization of 0.1 μm films of the same phase.
Expression of Cell Adhesion Molecules in Posterior Uveitis (1992)

Cells in the eye express surface molecules that direct leukocyte migration during ocular inflammation. We studied the expression of intercellular adhesion molecule-1, lymphocyte function-associated antigen-1, and endothelial leukocyte adhesion molecule-1 in six enucleated eyes from patients with uveitis and in seven normal control eyes. Lymphocyte function-associated antigen-1 was expressed on infiltrating lymphocytes and intercellular adhesion molecule-1 was expressed on endothelial cells of retinal and choroidal blood vessels and the retinal pigment epithelium in all uveitic eyes, but in none of the normal control eyes. Ocular inflammatory cells stained strongly positive for tumor necrosis factor alpha in all eyes with uveitis, but four of six uveitic eyes showed mild staining for tumor necrosis factor beta and interferon gamma. Cell adhesion molecules are expressed in eyes with posterior uveitis and may be regulated by cytokines such as tumor necrosis factor alpha.
Completeness conditions for mixed strategy bidirectional parsing (1999)

It has been suggested that, in certain circumstances, it might be useful for a grammar-writer to annotate which rules are to be used bottom-up and which are to be used top-down within a parser, using a bidirectional variant of the active chart parsing technique. The formal properties of such systems have not been fully explored. One limitation of this mixed strategy technique is that certain annotations of rules can lead to incompleteness; that is, there may be valid analyses of the input string which cannot be found by the parser. We formalise a fairly natural notion of mixed strategy bidirectional parsing for context free grammars, in which one or more symbols within a rule may be annotated as “triggers ” so that the rule is either top-down (triggered from its left-hand side), or bottom-up (triggered from element(s) of its right-hand side). We define a decidable property of annotated grammars, such that any grammar with this property is provably complete. There are, however, some complete annotations of grammars which fall outside this decidable class. We show that membership of this wider class is undecidable. These results suggest that the mixed strategy approach is of rather limited usefulness, regardless of whether it is empirically efficient or not.
A Secure Model for Electronic Contract Enactment, Monitoring and Management (2009)

With the rapid development of e-commerce, electronic contracts are not secure enough for both businessmen and government, due to the absence of authentication, integrality, non-repudiation, uniform specification and centralized management. We propose that e-contract should involve digital signature as its primary element, and the E-Contract Record Center should be introduced into the management of e-contract. In this paper, we present a model for electronic contract enactment, monitoring and management based on the security view. Additional, a framework for e-contract management is presented with the purpose of regularizing the e-commerce market, protecting businessmen's right and interests, and facilitating governmental monitoring of the e-commerce market, where we define a lifecycle of e-contract and recounted the establishment process of e-contract. Finally, we present implement architecture for the model and framework given above, which give the service and module design of two systems: e-contract system and ECRC system.