gebhart/patrepeval huggingface dataset:
Effect of thermal cycles on ferrite content of austenitic stainless steel (1999)

The properties of austenitic stainless steel weld metals are strongly influenced by the duplex structure of austenite and ferrite. The objective of the present study was to investigate the effect of thermal cycles on the ferrite content in austenitic stainless steel weld metal, and to explore the ferrite–austenite solid state transformation of austenitic stainless steel weld metal. The results indicate that the peak temperature, cooling rate, and number of thermal cycles have a significant effect on ferrite content in the austenitic stainless steel weld. As the cooling rate increases, or the number of thermal cycles decreases, the amount of retained ferrite is increased at room temperature. New δ ferrite phase can be formed if the reheating peak temperature is above the optimum γ solvus temperature of austenitic stainless steel, and this new δ ferrite can be retained under rapid cooling conditions.
Designing the World Wide Web for people with disabilities (1996)

The emergence of the World Wide Web has made it possible for individuals with appropriate computer and telecommunications equipment to interact as never before. An explosion of next-generation information systems are flooding the commercial market. This cyberspace convergence of data, computers, networks, and multimedia presents exciting challenges to interface designers. However, this "new technology frontier" has also created enormous roadblocks and barriers for people with disabilities. This panel will discuss specific issues, suggest potential solutions and solicit contributions required to design an accessible Web interface that includes people with disabilities.
Effects of tumour necrosis factor and alpha interferon on chronic B cell malignancies. (1988)

Tumour necrosis factor (TNF) induces the lysis of many malignant cells in vitro and regression of some tumours in vivo. However, TNF is also a growth factor for normal fibroblasts, T cells and B cells and we have recently shown that TNF can also act as a growth factor for chronic B cell neoplasms, including hairy cell leukaemia and B-CLL. In these cells it promotes proto-oncogene expression, RNA and DNA synthesis and increases overall cell survival. Stimulation appears to be autocrine in nature since exposure of the neoplastic cells to recombinant TNF protein induces the corresponding messenger RNA and synthesis of the protein itself. TNF induced proto-oncogene expression and DNA synthesis occur over a substantially longer time period than when the cells are stimulated with agents such as TPA and Calcium ionophore (2), but we have no evidence that the delay represents the time taken to generate TNF dependent secondary cytokines such as IL-1 and IL6. Alpha interferon opposes TNF mediated activation and our recent data indicate that this effect is independent of alpha interferon down regulation of TNF receptors. It appears to be related instead to a decreased accumulation of TNF mRNA which occurs contemporaneously with an alpha interferon induced rise in 2-5 A synthetase. If TNF dependent growth is important for the survival of B-CLL cells, then agents which mimic alpha interferon or which block TNF induced autocrine growth would be predicted to be of therapeutic benefit.
The “Ligamentization” Process in Human Anterior Cruciate Ligament Reconstruction with Autogenous Patellar and Hamstring Tendons (2005)

After anterior cruciate ligament reconstruction with autografts, biochemical characteristics of the graft resembled those of the native anterior cruciate ligament. These findings suggest that, regarding the amount of collagen crosslinks and their architecture, the phenomenon of ligamentization occurs in the successfully reconstructed human anterior cruciate ligament within 1 year after operation.
Time lapse refraction seismic ‐ a tool for monitoring carbonate fields? (2004)

Time lapse refraction seismic has potential for accurate estimation of reservoir velocity changes. Careful processing using rugby‐shaped fk‐filters, followed by RMS amplitude analysis versus offset is used. Typically, the RMS amplitude level peaks at an offset values slightly larger than the critical offset. By measuring the shift in this peak between the base line and monitor survey, it is possible to estimate the velocity change in the reservoir layer.
Incorporation of Personal Single Nucleotide Polymorphism (SNP) Data into a National Level Electronic Health Record for Disease Risk Assessment, Part 2: The Incorporation of SNP into the National Health Information System of Turkey (2014)

Our results emphasized that even though the existing NHIS-T messaging infrastructure supports the integration of SNP data and clinicogenomic association, it is critical to develop a national level, accredited knowledge base and better end-user systems for the interpretation of genomic, clinical, and envirobehavioral parameters.
Compensation techniques for geophone response used as vibration sensor in seismic applications (2017)

With prolific usage of vibration analysis to extract information about different structures (buildings and bridges etc.), vibration sensors have become an important device in Structural Health Monitoring (SHM). In this paper, we target geophone which is a commonly used sensor in SHM. Each geophone is unique with regard to application, sensitivity, and electrical characteristics. For the geophone that has been used in this study, we focused on the low frequency response to develop an optimum conditioning circuit for the sensor. Geophone response compensator is essential for conditioning vibration signals at very low frequencies. In this article, we have presented two different techniques to reconstruct the low frequency response characteristics of the geophone. Several analog electronic circuits to establish the feasibility of the suggested techniques for vibration signal conditioning by the geophone on hand are presented in this article.
Kinetics of inactivation of membrane-bound factor Va by activated protein C. Protein S modulates factor Xa protection. (1988)

Kinetic analyses were done to determine what effect factor Xa and protein S had on the activated protein C (APC)-catalyzed inactivation of factor Va bound to phospholipid vesicles or human platelets. In the presence of optimal concentrations of phospholipid vesicles and Ca2+, a Km of 19.7 +/- 0.6 nM factor Va and a kcat of 23.7 +/- 10 mol of factor Va inactivated/mol of APC/min were obtained. Added purified plasma protein S increased the maximal rate of factor Va inactivation only 2-fold without effect on the Km. Protein S effect was unaltered when the phospholipid concentration was varied by 2 orders of magnitude. The reaction on unactivated human platelets yielded a Km = 12.5 +/- 2.6 nM and kcat = 6.2 +/- 0.6 mol of factor Va inactivated/mol of APC/min. Added purified plasma protein S or release of platelet protein S by platelet activation doubled the kcat value without affecting the Km. Addition of a neutralizing anti-protein S antibody abrogated the effect of plasma protein S or platelet-released protein S, but was without effect in the absence of plasma protein S or platelet activation. Studies with factor Xa indicated that factor Xa protects factor Va from APC-catalyzed inactivation by lowering the effective concentration of factor Va available to interact with APC. From these data a dissociation constant of less than 0.5 nM was calculated for the interaction of factor Xa with membrane-bound factor Va. Protein S abrogated the ability of factor Xa to protect factor Va from inactivation by APC without affecting the interaction of factor Xa with factor Va. These combined data suggest that one physiological function of protein S is to allow the APC-catalyzed inactivation of factor Va in the presence of factor Xa.
Site‐directed mutagenesis of the FAD‐binding histidine of 6‐hydroxy‐D‐nicotine oxidase (1989)

In 6-hydroxy-D-nicotine oxidase (6-HDNO) FAD is covalently bound to His71 of the polypeptide chain by an 8 alpha-(N3-histidyl)-riboflavin linkage. The FAD-binding histidine was exchanged by site-directed mutagenesis to either a Cys- or Tyr-residue, two amino acids known to be involved in covalent binding of FAD in other enzymes, or to a Ser-residue. None of the amino acid replacements for His71 allowed covalent FAD incorporation into the 6-HDNO polypeptide. Thus, the amino acid residues involved in covalent FAD-binding require a specific polypeptide surrounding in order for this modification to proceed and cannot be replaced with each other. Enzyme activity was completely abolished with Tyr in place of His71. 6-HDNO activity with non-covalently bound FAD was found with 6-HDNO-Cys and to a lesser extent also with 6-HDNO-Ser. However, the Km values for 6-HDNO-Cys and 6-HDNO-Ser were increased approximately 20-fold as compared to 6-HDNO-His. Both mutant enzymes, in contrast to the wild-type enzyme, needed additional FAD in the enzymatic assay (50 microM for 6-HDNO-Ser and 10 microM for 6-HDNO-Cys) for maximal enzyme activity.
La cultura organizacional en el Sistema Nacional de Ciencia y Tecnología para la Innovación (SINCITi) de Costa Rica: un análisis a partir de la planificación estratégica institucional (2010)

El avance mundial de las Tecnologias de la Informacion y la Comunicacion (TICs), la apuesta por la innovacion, el crecimiento de las oportunidades academicas y la globalizacion del comercio, entre varias circunstancias, han 
ampliado el espacio en que actuan los profesionales del conocimiento, 
junto al aumento de las necesidades de los publicos de interes y a la modificacion de la vida 
cotidiana y las relaciones en general. Habitamos un mundo donde la ciencia, la tecnologia
y la innovacion son conceptos cada vez 
mas presentes.
Idealmente, este desarrollo en ciencia y
tecnologia (CyT) debe ser convertido en aumento 
en la calidad de vida de la poblacion en general. 
Para tal fin, en la puesta en marcha de una estrategia-pais, es indispensable la colaboracion del profesional en comunicacion organizacional
o relaciones publicas , quien se encarga de proponer, administrar, fortalecer y evaluar los procesos comunicativos en los cuales intervienen las organizaciones, y formula las alternativas estrategicas para establecer relaciones duraderas 
con diferentes publicos, entre otros aportes.
Spinal phospholipase A2 in inflammatory hyperalgesia: Role of the small, secretory phospholipase A2 (2005)

Current work emphasizes that peripheral tissue injury and inflammation results in a heightened sensitivity to subsequent noxious input (hyperalgesia) that is mediated in large part by the spinal synthesis and release of eicosanoids, in particular prostaglandins. Secreted phospholipase A(2)s (sPLA(2)s) form a class of structurally related enzymes that release arachidonic acid from cell membranes that is further processed to produce eicosanoids. We hypothesized that spinal sPLA(2)s may contribute to inflammation-induced hyperalgesia. Spinal cord tissue and cerebrospinal fluid were collected from rats for assessment of sPLA(2) protein expression and sPLA(2) activity. A basal sPLA(2) protein expression and activity was detected in spinal cord homogenate (87+/-17 pmol/min/mg), though no activity could be detected in cisternal cerebrospinal fluid, of naive rats. The sPLA(2) activity did not change in spinal cord tissue or cerebrospinal fluid assessed over 8 h after injection of carrageenan into the hind paw. However, the sPLA(2) activity observed in spinal cord homogenates was suppressed by addition of LY311727, a selective sPLA(2) inhibitor. To determine the role of this spinal sPLA(2) in hyperalgesia, we assessed the effects of lumbar intrathecal (IT) administration of LY311727 in rats with chronic IT catheters in three experimental models of hyperalgesia. IT LY311727 (3-30 microg) dose-dependently prevented intraplantar carrageenan-induced thermal hyperalgesia and formalin-induced flinching, at doses that had no effect on motor function. IT LY311727 also suppressed thermal hyperalgesia induced by IT injection of substance P (30 nmol). Using in vivo spinal microdialysis, we found that IT injection of LY311727 attenuated prostaglandin E(2) release into spinal dialysate otherwise evoked by the IT injection of substance P. Taken together, this work points to a role for constitutive sPLA(2)s in spinal nociceptive processing.
A unified framework for recommending diverse and relevant queries (2011)

Query recommendation has been considered as an effective way to help search users in their information seeking activities. Traditional approaches mainly focused on recommending alternative queries with close search intent to the original query. However, to only take relevance into account may generate redundant recommendations to users. It is better to provide diverse as well as relevant query recommendations, so that we can cover multiple potential search intents of users and minimize the risk that users will not be satisfied. Besides, previous query recommendation approaches mostly relied on measuring the relevance or similarity between queries in the Euclidean space. However, there is no convincing evidence that the query space is Euclidean. It is more natural and reasonable to assume that the query space is a manifold. In this paper, therefore, we aim to recommend diverse and relevant queries based on the intrinsic query manifold. We propose a unified model, named manifold ranking with stop points, for query recommendation. By turning ranked queries into stop points on the query manifold, our approach can generate query recommendations by simultaneously considering both diversity and relevance in a unified way. Empirical experimental results on a large scale query log of a commercial search engine show that our approach can effectively generate highly diverse as well as closely related query recommendations.
Intrusion Attack Pattern Analysis and Signature Extraction for Web Services Using Honeypots (2008)

With the increasing popularity of Web services, attackers are getting attracted to hack the Web services and the servers on which they run. One of the major threats is that of intruders which may maliciously try to access the data or services. Thus there is a need to protect the servers on which Web services are running from intruders. Therefore, intrusion detection systems need to be employed. Signature based IDS are popularly being used. Honeypots are a highly flexible security tool with differing applications for security. They are a security resource that does not have any production or authorized activity but have an important use in intrusion prevention, detection and information gathering. Honeypot collects very little data and what it collects is normally of high value. This information can be used in extraction of intrusion detection signature. In this paper we have proposed a method to analyze the attacks and generate signatures for Web services.
Nanoparticles Effects of Red Grape (Vitis vinifera) Seeds and Grape Seeds Powder on Obese Hyperlipidemic Rats (2016)

Nanotechnology is emerging as a rapidly growing field with its wide application in science and technology for manufacturing of new materials at nanoscale level .This study aims to examine the effect of the nanoparticles of cellulose from grape seeds on obese hyperlipidemic rats.
Gases Liberated during the High Voltage Electron Irradiation of Polyethylene (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGases Liberated during the High Voltage Electron Irradiation of PolyethyleneElliott J. Lawton, P. D. Zemany, and J. S. BalwitCite this: J. Am. Chem. Soc. 1954, 76, 13, 3437–3439Publication Date (Print):July 1, 1954Publication History Published online1 May 2002Published inissue 1 July 1954https://pubs.acs.org/doi/10.1021/ja01642a018https://doi.org/10.1021/ja01642a018research-articleACS PublicationsRequest reuse permissionsArticle Views69Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
An Acid Exchanged Montmorillonite Clay-Catalyzed Synthesis of Polyepichlorhydrin (2003)

“Maghnite”, a montmorillonite sheet silicate clay, exchanged with protons to produce “H-Maghnite” is an efficient catalyst for cationic polymerisation of many heterocyclic and vinylic monomers (Belbachir, M. U.S. Patent. 066969.0101 –2001). The structural compositions of both “Maghnite” and “H-Maghnite” have already been determined. Epichlorhydrin monomer, which is polymerizable by a cationic process (Odian,G. La Polymerisation: Principes et Applications; Ed.Technica: New York, 1994; pp 222-226), was used to elucidate the polymerization cationic character. The polymerization was performed under optimum conditions at 20°C. Experiments revealed that the polymerisation induced by “H-Maghnite” proceeds in bulk. In bulk polymerization, Epichlorhydrin conversion increases with increasing “H-Maghnite” concentration and temperature.
Preparation of 2,6-dioxabicyclo[3.3.0]octan-3,7-dione and its application to the synthesis of (.+-.)-eldanolide. (1988)

2, 6-Dioxabicyclo[3.3.0]octan-3, 7-dione seems to be a promising compound for the synthesis of natural products such as epoxyeicosatrienoic acid, laurediol, and eldanolide. This compound, consisting of two γ-lactones, could be prepared by double lactonization of the silver salt of trans-3-hexenedioic acid using iodine. Starting with this bis-lactone, (±)-eldanoide could by synthesized in a stereocontrolled manner.
The kinetics of the gas-phase photochlorination of trichloroethylene (1957)

The first page of this article is displayed as the abstract.
Aspect Ratio Dependence of the Elastic Properties of ZnO Nanobelts (2007)

The Young's modulus of ZnO nanobelts was measured with an atomic force microscope by means of the modulated nanoindentation method. The elastic modulus was found to depend strongly on the width-to-thickness ratio of the nanobelt, decreasing from about 100 to 10 GPa, as the width-to-thickness ratio increases from 1.2 to 10.3. This surprising behavior is explained by a growth-direction-dependent aspect ratio and the presence of stacking faults in nanobelts growing along particular directions.
Photo-Induced Complex Permittivity Measurements Of Semiconductors At 9 Ghz (1984)

This paper describes a microwave method for determining the photo-induced incremental complex permittivity of semiconductor materials such as Si, Ge, Te, and-- also for the determination of the average collision time. An unbalanced bridge technique is used which allows sensitive measurements even at low optical illumination levels, with relatively simple computational procedures. This method is thus useful for evaluating the potential usefulness of semiconductors for optically controlled microwave devices.
Quantitative assessment of the anterior segment using ultrasound biomicroscopy (2000)

The development of ocular imaging devices has progressed rapidly during the past 10 years. Ultrasound biomicroscopy has revolutionized the evaluation of the anterior segment of the eye. The qualitative information gathered using this technology has contributed to our understanding of the pathophysiology of angle-closure glaucoma, pigmentary glaucoma, and a variety of other anterior segment disorders. However, the area of quantitative analysis of ultrasound biomicroscopic images remains largely to be developed. This review describes the role of ultrasound biomicroscopy in the measurement of the anatomic structures and their configurations within the anterior segment. Included are previously published and established methods as well as methods in their early stages of development. Application of quantitative image analysis techniques should yield significant information about mechanisms of appositional angle closure, dynamic functions of the iris, accommodation, and presbyopia.
Radiance modelling using the P3 approximation (1998)

Light dosimetry is an essential component of effective photodynamic therapy (PDT) of tumours. Present PDT light dosimetry techniques rely on fluence-based models and measurements. However, in a previous paper by Barajas et al, radiance-based light dosimetry was explored as an alternative approach. Although successful in demonstrating the use of Monte Carlo (MC) simulations of radiance in tissue optical characterization, the MC proved time consuming and impractical for clinical applications. It was proposed that an analytical solution to the transport equation for radiance would be desirable as this would facilitate and increase the speed of tissue characterization. It has been found that the P3 approximation is one such potential solution. Radiance and fluence expressions based on the P3 approximation were used to optically characterize an Intralipid-based tissue phantom of varying concentration of scatterer (Intralipid) and absorber (methylene blue) using a plane wave illuminated, semi-infinite medium geometry. The results obtained compare favourably with the Grosjean approximation of fluence (a modified diffusion theory) using the same optical parameters (mu(a), mu(s), g). The results illustrate that radiance-based light dosimetry is a viable alternative approach to tissue characterization and dosimetry. It is potentially useful for clinical applications because of the limited number of invasive measurements needed and the speed at which the tissue can be characterized.
Antagonist of Pituitary Adenylate Cyclase Activating Polypeptide Suppresses Prolactin Secretion without Changing the Activity of Dopamine Neurons in Lactating Rats (2001)

Pituitary adenylate cyclase activating polypeptide (PACAP) is a relatively new neuropeptide, and it has a potent stimulatory effect on adenylate cyclase activity in rat pituitary cells. However, the role of PACAP in the physiological control of prolactin (PRL) secretion is still unclear. In the present study, we investigated the physiological significance of endogenous PACAP on PRL secretion in lactating rats. On lactation days 7-8, pups were separated from their mother rats for 5 h before the onset of suckling and PACAP6-38 (16 microg), a receptor antagonist, was injected through the lateral ventricle cannula just after the removal of pups. The effects of PACAP6-38 on PRL and oxytocin secretion, and on the activity of tyrosine hydroxylase (TH), were examined after the onset of suckling. Administration of PACAP6-38 inhibited PRL levels in response to suckling, but it did not affect the activity of TH, as measured by DOPA accumulation at 15 min after administration of NSD 1015 (25.0 mg/kg), an L-aromatic amino acid decarboxylase inhibitor, or the plasma concentrations of oxytocin in lactating rats. Injection of alpha-methyl-p-tyrosine (alpha-MT; 50 mg/kg), an inhibitor of dopamine synthesis, increased PRL levels, and suckling caused a further increase in the plasma concentrations of PRL. An injection of PACAP6-38 (i.c.v.) also inhibited the PRL response to suckling under dopamine depletion. These results suggest that endogenous PACAP acts as a neurotransmitter or neuromodulator within the hypothalamus and plays an important role for PRL secretion in lactating rats. Endogenous PACAP may regulate PRL secretion, possibly mediated by PRL-releasing factors such as vasoactive intestinal polypeptide or vasopressin.