gebhart/patrepeval huggingface dataset:
Recent trends in the management of lymphomas at M.D. Anderson Cancer Center. (1990)

The overall therapeutic strategy for the management of lymphomas at the M.D. Anderson Cancer Center consists of devising new drug combinations that are tested first in patients with relapsed lymphoma and, if successful, are then incorporated into first-line management. This article describes the preliminary results of the alternating triple therapy (ATT) first-line regimen for patients with M.D. Anderson stages B, C, and D of intermediate-grade lymphomas. This regimen is based on three non-cross-resistant combinations, two of which were originally developed as salvage therapy. Statistically significant improvement in the overall survival and failure-free survival at 1 year has already been seen for the stage D patients (high tumor burden and high lactate dehydrogenase levels). A new therapeutic strategy in current use for patients with Ann Arbor stages III and IV low-grade lymphoma is also described. This regimen consists of CHOP-Bleo (cyclophosphamide, doxorubicin, vincristine, prednisone-bleomycin) alternating with ESHAP (etoposide, Solu-medrol [methylprednisolone, Upjohn Company], Ara-C [cytarabine], platinum) and NOPP (Novantrone [mitoxantrone, American Cyanamid Company], Oncovin [vincristine Eli Lilly and Company], procarbazine, prednisone). Maintenance interferon (IFN) is also used for 1 year. Finally, the current salvage regimen in use at the M.D. Anderson Cancer Center is described. This MINE-ESHAP regimen consists of an induction with mesna, ifosfamide, Novantrone (mitoxantrone), and etoposide, which is administered until maximum response and followed by consolidation with 3 to 6 courses of ESHAP. The preliminary results of this regimen are encouraging, but more follow-up is required before any conclusions can be drawn.
Automated Online Exam Proctoring (2017)

Massive open online courses and other forms of remote education continue to increase in popularity and reach. The ability to efficiently proctor remote online examinations is an important limiting factor to the scalability of this next stage in education. Presently, human proctoring is the most common approach of evaluation, by either requiring the test taker to visit an examination center, or by monitoring them visually and acoustically during exams via a webcam. However, such methods are labor intensive and costly. In this paper, we present a multimedia analytics system that performs automatic online exam proctoring. The system hardware includes one webcam, one wearcam, and a microphone for the purpose of monitoring the visual and acoustic environment of the testing location. The system includes six basic components that continuously estimate the key behavior cues: user verification, text detection, voice detection, active window detection, gaze estimation, and phone detection. By combining the continuous estimation components, and applying a temporal sliding window, we design higher level features to classify whether the test taker is cheating at any moment during the exam. To evaluate our proposed system, we collect multimedia (audio and visual) data from $\text{24}$ subjects performing various types of cheating while taking online exams. Extensive experimental results demonstrate the accuracy, robustness, and efficiency of our online exam proctoring system.
10 Gbit/s transmission over 90–127 km in thewavelength range 1530–1560 nm using an InP-based Mach-Zehnder modulator (1996)

An InP-based Mach-Zehnder modulator has been realised, and transmission over a standard fibre at 10 Gbit/s over 90–127 km has been successfully demonstrated in a single-arm configuration scheme, in the wavelength range 1530–1560 nm. The sole bias voltage has been adjusted to take into account the wavelength dependence of the electro-optic efficiency of the phase modulator material.
Genetic variation and heritability for cotton seed, fiber and oil traits in Gossypium hirsutum L. (2010)

The research work pertaining to the study of genetic variability, heritability, genetic gain and correlation for cottonseed, fiber and cottonseed oil % in Gossypium hirsutum cultivars was conducted during 2005 at NWFP Agricultural University Peshawar, Pakistan. Analysis of variance manifested highly significant differences among the genotypes for all the traits except seeds per locule. Genetic potential range of eight cotton cultivars for different parameters was recorded i.e. seeds locule -1 (6.33 to 6.60), seeds boll -1 (26.10 to 28.47), seed index (8.61 to 9.69 g), lint index (5.35 to 6.05 g), lint % (35.17 to 38.13 %), seed cotton yield (1200 to 2450 kg ha -1 ) and cottonseed oil % (27.52 to 30.15%). Genetic variances were found almost greater than the environmental variances for all the traits except seeds locule -1 and seed index. High broad sense heritability and selection response were also formulated for seeds boll -1 (0.67, 0.84), seed index (0.77, 0.47 g), lint index (0.96, 0.33 g), lint % (0.96, 1.66 %), seed cotton yield (0.98, 643.16 kg) and cottonseed oil % (0.87, 1.28 %), respectively. Correlation of yield with other traits was found positive for majority of traits except seeds locule -1 and cotton seed oil %. Seed cotton yield is our ultimate goal in growing cotton besides lint %. Highest seed cotton yield was recorded in CIM-499 followed by CIM-473, CIM-496 and CIM-506 and were also found as the 2 nd and 3 rd top scoring genotypes for seeds per boll, seed index, lint % and cottonseed oil %. Cultivar SLH-279 performed better for lint index, lint % and oil %. This type of correlation is rarely found and ultra desirable by the cotton breeders and a little genetic gain in seed and lint traits, and oil content is a great accomplishment.
Porcine epidemic diarrhea virus: An emerging and re-emerging epizootic swine virus (2015)

The enteric disease of swine recognized in the early 1970s in Europe was initially described as "epidemic viral diarrhea" and is now termed "porcine epidemic diarrhea (PED)". The coronavirus referred to as PED virus (PEDV) was determined to be the etiologic agent of this disease in the late 1970s. Since then the disease has been reported in Europe and Asia, but the most severe outbreaks have occurred predominantly in Asian swine-producing countries. Most recently, PED first emerged in early 2013 in the United States that caused high morbidity and mortality associated with PED, remarkably affecting US pig production, and spread further to Canada and Mexico. Soon thereafter, large-scale PED epidemics recurred through the pork industry in South Korea, Japan, and Taiwan. These recent outbreaks and global re-emergence of PED require urgent attention and deeper understanding of PEDV biology and pathogenic mechanisms. This paper highlights the current knowledge of molecular epidemiology, diagnosis, and pathogenesis of PEDV, as well as prevention and control measures against PEDV infection. More information about the virus and the disease is still necessary for the development of effective vaccines and control strategies. It is hoped that this review will stimulate further basic and applied studies and encourage collaboration among producers, researchers, and swine veterinarians to provide answers that improve our understanding of PEDV and PED in an effort to eliminate this economically significant viral disease, which emerged or re-emerged worldwide.
Codebook searching for 4.8 kbps CELP speech coder (2002)

The authors describe an implementation of fast algorithms for codebook searching used in code-excited linear predictive (CELP) speech coding. They present details of the algorithms including (i) fast conversion of line spectrum pair parameters to linear predictive coding parameters, and (ii) fast searches of the parameters of adaptive and stochastic codebooks. The description can be readily used for CELP implementations, such as on (i) high-quality low-bit-rate speech transmission in point-to-point or store-and-forward mode, and (ii) efficient speech storage in speech recording and multimedia databases. The algorithms have been implemented on an IBM-PC AT equipped with a TMS320C30 module and a SUN Sparcstation 10 for the development of packet radio speech transmission and voice mail applications, respectively.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Near-field gap effects on small microcavity whispering-gallery mode resonators (2006)

The near-field gap effects are investigated in planar dielectric microdisc and waveguide coupling structures, emphasizing miniaturization of integrated sensor systems. The simulation results show that the resonance frequency is not obviously affected by the gap dimension when the gap between a microcavity and its coupler is larger than 300 nm. However, the resonance frequency shifts observably with a further decreasing gap to the nanometre level. This shift is generally larger than the cavity resonance linewidth in the 10 µm diameter microdisc system, but is comparable to the cavity resonance linewidth in the 2 µm diameter microdisc system. With increasing gap, the cavity Q increases exponentially until it is saturated at a limit Q factor. An optimal gap dimension exists for maximum light energy transfer and storage. The concept of optimum gap is introduced and defined at the gap dimension where half-maximum energy storage capability is achieved; meanwhile, the cavity Q is high and the resonance frequency remains stable.
Biobarriers Used in Shallow Burial Ground Stabilization (1982)

Three types of barriers to plant root growth were investigated. Previously, a long-term barrier was created by placing loose rock between buried waste and topsoil; this barrier successfully prevented plant root and animal intrusions into buried waste. Then an intermediate-term barrier was made by encapsulating phytotoxin into a polymer. The polymer regulated phytotoxin release and also acted to prolong the toxin’s effectiveness. A short-term barrier was made by spraying phytotoxin directly onto a thin layer of soil between the waste and topsoil. Trifluralin proved to be the most effective of seven phytotoxins studied because it prevented root penetration of the barrier. Trifluralin is not translocatable and allows nonaffected plant parts to grow normally.
Synthesis of Monodisperse TiO<sub>2</sub>−Paraffin Core−Shell Nanoparticles for Improved Dielectric Properties (2010)

Core-shell structures of oxide nanoparticles having a high dielectric constant, and organic shells with large breakdown field are attractive candidates for large electrical energy storage applications. A high growth temperature, however, is required to obtain the dielectric oxide nanoparticles, which affects the process of core-shell formation and also leads to poor control of size, shape, and size-distribution. In this communication, we report a new synthetic process to grow core-shell nanoparticles by means of an experimental method that can be easily adapted to synthesize core-shell structures from a variety of inorganic-organic or inorganic-inorganic materials. Monodisperse and spherical TiO2 nanoparticles were produced at room temperature as a collimated cluster beam in the gas phase using a cluster-deposition source and subsequently coated with uniform paraffin nanoshells using in situ thermal evaporation, prior to deposition on substrates for further characterization and device processing. The paraffin nanoshells prevent the TiO2 nanoparticles from contacting each other and also act as a matrix in which the volume fraction of TiO2 nanoparticles was varied by controlling the thickness of the nanoshells. Parallel-plate capacitors were fabricated using dielectric core-shell nanoparticles having different shell thicknesses. With respect to the bulk paraffin, the effective dielectric constant of TiO2-paraffin core-shell nanoparticles is greatly enhanced with a decrease in the shell thickness. The capacitors show a minimum dielectric dispersion and low dielectric losses in the frequency range of 100 Hz-1 MHz, which are highly desirable for exploiting these core-shell nanoparticles for potential applications.
Multicode Multicarrier Interleave Division Multiple Access Communication (2006)

A new mulitcode multicarrier interleave division multiple access (MC-MC-IDMA) system is proposed and analyzed in frequency selective channels. The system supports different modulation schemes for variables data rates. Each user transmits his message by choosing a sequence from an orthogonal code-set. An MC-MC-IDMA system achieves spreading gains both in time and frequency domains. Bit error rate of the system is derived and simulation results are presented.
Conditions Sufficient for Nonsynaptic Epileptogenesis in the CA1 Region of Hippocampal Slices (2002)

Nonsynaptic mechanisms exert a powerful influence on seizure threshold. It is well-established that nonsynaptic epileptiform activity can be induced in hippocampal slices by reducing extracellular Ca(2+) concentration. We show here that nonsynaptic epileptiform activity can be readily induced in vitro in normal (2 mM) Ca(2+) levels. Those conditions sufficient for nonsynaptic epileptogenesis in the CA1 region were determined by pharmacologically mimicking the effects of Ca(2+) reduction in normal Ca(2+) levels. Increasing neuronal excitability, by removing extracellular Mg(2+) and increasing extracellular K(+) (6-15 mM), induced epileptiform activity that was suppressed by postsynaptic receptor antagonists [D-(-)-2-amino-5-phosphonopentanoic acid, picrotoxin, and 6,7-dinitroquinoxaline-2,3-dione] and was therefore synaptic in nature. Similarly, epileptiform activity induced when neuronal excitability was increased in the presence of K(Ca) antagonists (verruculogen, charybdotoxin, norepinephrine, tetraethylammonium salt, and Ba(2+)) was found to be synaptic in nature. Decreases in osmolarity also failed to induce nonsynaptic epileptiform activity in the CA1 region. However, increasing neuronal excitability (by removing extracellular Mg(2+) and increasing extracellular K(+)) in the presence of Cd(2+), a nonselective Ca(2+) channel antagonist, or veratridine, a persistent sodium conductance enhancer, induced spontaneous nonsynaptic epileptiform activity in vitro. Both novel models were characterized using intracellular and ion-selective electrodes. The results of this study suggest that reducing extracellular Ca(2+) facilitates bursting by increasing neuronal excitability and inhibiting Ca(2+) influx, which might, in turn, enhance a persistent sodium conductance. Furthermore, these data show that nonsynaptic mechanisms can contribute to epileptiform activity in normal Ca(2+) levels.
Virulence genotypes of clinical SalmonellaSerovars from broilers in Egypt (2016)

These results will help in understanding the spread of virulence genotypes and antibiotic resistance among Salmonella serovars in broilers.
Antibacterial activity of silver bionanocomposites synthesized by chemical reduction route (2012)

The antibacterial activity of Ag NPs with size less than 20 nm was demonstrated and showed positive results against Gram-negative and Gram-positive bacteria. The Ag NPs stabilized well in the polymers matrix.
A communication network architecture for transportation information systems (2002)

An emerging application of mobile computing and communication is the delivery of information related to the transportation system to drivers and travelers. Such real-time information would be very valuable in providing services such as pre-trip planning, route guidance, intermodal transportation, yellow pages, and ride matching and reservation. This so-called advanced traveler information system (ATIS) is an important subset of an intelligent transportation system (ITS). The authors are developing an ATIS operational field test called SWIFT (Seattle wide-area information for travelers) in the Seattle metropolitan area which uses technological advances in wireless communication, personal digital assistants (PDA), and traffic modeling and analysis. SWIFT uses an advanced 19 kbps FM subcarrier broadcast medium for the delivery of transportation information as well as personal paging information. Preliminary description of the logical and physical architecture of the SWIFT system along with communication loading analysis for this system, are presented.
Pharmacologic treatment of acute and chronic stress following trauma: 2006. (2006)

This article reviews pharmacologic treatment options for posttraumatic stress disorder (PTSD), focusing on goals of pharmacotherapy and the clinical trial evidence for drug treatments available for PTSD. The selective serotonin reuptake inhibitors (SSRIs) are recommended as first-line therapy for PTSD; the roles of these and other drug classes including anticonvulsants, mood enhancers, atypical antipsychotic agents, benzodiazepines, alpha1-adrenergic antagonists, and beta-blockers in achieving improvement in PTSD symptom and outcome scores, achieving remission, and avoiding relapse are discussed. Treatment of PTSD in association with other comorbid conditions is addressed, and the role of pharmacotherapy in treating early PTSD and acute stress disorder is examined. Dosing strategies for the SSRIs sertraline and paroxetine are provided, and an algorithm for PTSD pharmacotherapy is discussed.
Liver-Derived CTL in Hepatitis C Virus Infection: Breadth and Specificity of Responses in a Cohort of Persons with Chronic Infection (1998)

Hepatitis C virus (HCV)-specific CTL have been found within the inflammatory infiltrate of the liver of chronically infected individuals, but the breadth and specificity of the CTL response in relation to viral load are less well characterized. In this study, we analyzed the intrahepatic CTL response in liver biopsy specimens from 44 chronically infected subjects. Liver-infiltrating lymphocytes were expanded polyclonally in bulk cultures, and multiple clones were derived by limiting dilution. HCV-specific CTL responses directed at genotype 1a structural proteins were assessed in all subjects, and 22 subjects were tested more comprehensively using vectors expressing all structural and nonstructural HCV Ags. CTL responses were further characterized to determine the HLA restriction and optimal epitopes recognized. In those persons screened for recognition of all HCV Ags, HLA class I-restricted CTL were detected in 45%. Nineteen different CTL epitopes were identified, which were distributed throughout the genome; only one epitope was targeted by more than one person. In those persons with CTL responses, the breadth of response ranged from one to five epitopes. There was no correlation between the presence of a detectable CTL response and viral load. These results indicate considerable heterogeneity in detectable HCV-specific CTL responses in chronically infected persons. The mechanisms by which HCV persists during chronic infection remain to be clarified.
The Scattering Coefficient and Mass Concentration of Smoke from Some Australian Forest Fires (1974)

Smoke from large scale fuel reduction fires in Western Australia has been investigated from an aircraft; These fires are typically 10,000-20,000 acres in area with fuel loadings of 3-6 tons/acre. Measurements were made of mass concentration, scattering coefficient and total particulate production in the smoke. The results suggest that the mass concentration (g m-3) is equal to 0.24 times the scattering coefficient (m-1). About 1.8% of the fuel appears as particulate matter in the air above the fire.
Double‐Network Hydrogels Strongly Bondable to Bones by Spontaneous Osteogenesis Penetration (2016)

On implanting hydroxyapatite-mineralized tough hydrogel into osteochondral defects of rabbits, osteogenesis spontaneously penetrates into the gel matrix owing to the semi-permeablility of the hydrogel. The gradient layer (around 40 μm thick) contributes quite strong bonding of the gel to bone. This is the first success in realizing the robust osteointegration of tough hydrogels, and the method is simple and feasible for practical use.
On the capture probability for a large number of stations (1997)

The probability of capture under a model (for a land mobile radio direct sequence spread spectrum system) based on the ratio of the largest received power to the sum of interference powers is examined in the limit of a large number of transmitting stations. It is shown in great generality that the limit depends only on the capture ratio threshold and the roll-off exponent of the distribution of power received from a typical station. This exponent is insensitive to many typical channel effects such as Rician or Rayleigh fading and log-normal shadowing. The model is suitable for large systems with noncoherently combined interference.
High-Pressure Synthesis, Crystal Chemistry, and Ionic Conductivity of a Structural Polymorph of Li<sub>3</sub>BP<sub>2</sub>O<sub>8</sub> (2018)

A new structural polymorph of Li<sub>3</sub>BP<sub>2</sub>O<sub>8</sub> has been successfully synthesized via a solid-state reaction between Li<sub>3</sub>PO<sub>4</sub> and BPO<sub>4</sub> at 4 GPa and 600 °C. The high-pressure phase of Li<sub>3</sub>BP<sub>2</sub>O<sub>8</sub> (HP-Li<sub>3</sub>BP<sub>2</sub>O<sub>8</sub>) was found to crystallize in monoclinic symmetry with the cell parameters of a = 8.57010(4) Å, b = 11.11812(5) Å, c = 5.55380(3) Å, and β = 97.7269(3)° [space group P2<sub>1</sub>/ a (No. 14)]. HP-Li<sub>3</sub>BP<sub>2</sub>O<sub>8</sub> has a new crystal structure that has not been reported so far. The total ionic conductivities measured for the polycrystalline sample by alternating-currrent impedance were 3.4 × 10<sup>-7</sup> and 2.1 × 10<sup>-6</sup> S/cm at 399 and 456 K, respectively. The lithium ionic conductivity of HP-Li<sub>3</sub>BP<sub>2</sub>O<sub>8</sub> was higher than that of the low-pressure phase Li<sub>3</sub>BP<sub>2</sub>O<sub>8</sub> in the temperature range of 375-456 K. This is caused by the difference in the dimensions of the lithium arrangements between LP- and HP-Li<sub>3</sub>BP<sub>2</sub>O<sub>8</sub>.
Activated leukocyte cell adhesion molecule in breast cancer: prognostic indicator (2004)

In the present panel of breast cancer specimens, decreased levels of ALCAM correlated with the nodal involvement, the grade, the TNM stage, the NPI, and the clinical outcome (local recurrence and death). The data suggest that decreased ALCAM expression is of clinical significance in breast cancer, and that reduced expression indicates a more aggressive phenotype and poor prognosis.
Secure Untrusted Data Repository (SUNDR) (2003)

SUNDR is a network file system designed to store data securely on untrusted servers. SUNDR lets clients detect any attempts at unauthorized file modification by malicious server operators or users. SUNDR's protocol achieves a property called fork consistency, which guarantees that clients can detect any integrity or consistency failures as long as they see each other's file modifications. An implementation is described that performs comparably with NFS (sometimes better and sometimes worse), while offering significantly stronger security.