gebhart/patrepeval huggingface dataset:
Autologous Platelet Gel: An In Vitro Analysis of Platelet-Rich Plasma Using Multiple Cycles (2006)

Autologous platelet gel (APG) has become an expanding field for perfusionists. By mixing platelet-rich plasma (PRP) with thrombin and calcium, platelet gel is prepared and used in many surgical settings. There are many devices used to produce PRP. This study evaluates the Medtronic Magellan Autologous Platelet Separator. The purpose of this study was to show that processing two cycles of the same syringe could reduce the amount of blood required to produce a specific volume of PRP. Three 60-mL syringes of whole blood with anticoagulant were removed from 15 elective coronary artery bypass patients. Each syringe produced 9 mL of PRP and 1 mL was sent to the laboratory for analysis. The remaining whole blood in each syringe was processed a second time with a yield of 5 mL of PRP with 1 mL sent to the laboratory. With this data, the Magellan was assessed in three phases. The first phase focused on the consistency of the Magellan. Laboratory values of hematocrit, platelet count, white blood cell count, and fibrinogen were compared between each syringe processed by the device. The second phase dealt with the percentage of platelets in the PRP that the Magellan was able to capture. Finally, results of both cycles were combined and compared against baseline values. Most of the hematological factors evaluated between each syringe were consistent in both cycles. The Magellan was able to capture nearly 70% of all platelets in the PRP of the first cycle and 18.5% in the second cycle. By mathematically combining both cycles, platelet counts averaged 2.8 times baseline with a 3.3 times baseline increase when the volume of the two cycles was weighted. This weighted average was done to reflect a higher concentration of Cycle 1 platelets than Cycle 2 in each sample. This study proved that processing each syringe of whole blood twice could reduce blood requirements while maintaining an effective platelet yield and volume. It also showed that the Magellan does conform to benchmark testing done at Medtronic.
Aboriginal and Islander Views: Parent/Infant Play Group (1979)

The article is an account of a young Inala mother and her experience with the playgroup at the Inala Family Education Centre. The author reports that being at the playgroup helps her to teach and learn with her child and also share the experience of other mothers and learn from them.
Finite element analysis based on ant colony algorithm (2012)

The content formerly presented as the proceedings of this conference in IEEE Xplore was found to be unauthorized, and thus a wholly inaccurate representation of the proceedings of the conference.The content now presented as the proceedings of this conference has been verified as a true and accurate representation of the research presented at the conference. We apologize for this incident, and have taken steps to prevent this from happening in the future.
BAC-VAC, a novel generation of (DNA) vaccines: A bacterial artificial chromosome (BAC) containing a replication-competent, packaging-defective virus genome induces protective immunity against herpes simplex virus 1 (1999)

This study aimed to exploit bacterial artificial chromosomes (BAC) as large antigen-capacity DNA vaccines (BAC-VAC) against complex pathogens, such as herpes simplex virus 1 (HSV-1). The 152-kbp HSV-1 genome recently has been cloned as an F-plasmid-based BAC in Escherichia coli (fHSV), which can efficiently produce infectious virus progeny upon transfection into mammalian cells. A safe modification of fHSV, fHSVΔpac, does not give rise to progeny virus because the signals necessary to package DNA into virions have been excluded. However, in mammalian cells fHSVΔpac DNA can still replicate, express the HSV-1 genes, cause cytotoxic effects, and produce virus-like particles. Because these functions mimic the lytic cycle of the HSV-1 infection, fHSVΔpac was expected to stimulate the immune system as efficiently as a modified live virus vaccine. To test this hypothesis, mice were immunized with fHSVΔpac DNA applied intradermally by gold-particle bombardment, and the immune responses were compared with those induced by infection with disabled infectious single cycle HSV-1. Immunization with either fHSVΔpac or disabled infectious single cycle HSV-1 induced the priming of HSV-1-specific cytotoxic T cells and the production of virus-specific antibodies and conferred protection against intracerebral injection of wild-type HSV-1 at a dose of 200 LD 50 . Protection probably was cell-mediated, as transfer of serum from immunized mice did not protect naive animals. We conclude that BAC-VACs per se , or in combination with genetic elements that support replicative amplification of the DNA in the cell nucleus, represent a useful new generation of DNA-based vaccination strategies for many viral and nonviral antigens.
Drug Therapy of Parkinsonism (1972)

FOR more than 150 years, Parkinson's disease has been known as one of the major "crippling" neurologic disorders of middle life. Easily recognizable as a clinical entity, it usually begins insidiously, with minimal signs and symptoms that gradually become more pronounced and are followed by a succession of additional manifestations. Ever increasing motor disability occurs, culminating ultimately in most cases in severe invalidism. Despite impressive recent advances in knowledge resulting in some changes in concepts of Parkinsonism, and the development of new agents for its treatment, the cause of this disorder remains unknown, its pathophysiology a subject of speculation, and . . .
Run out of steam? Here's how to create a growth action plan (2005)

Purpose Looks at why traditional growth tactics have become less effective and why it is necessary to balance short term moves with new business building. Looks at understanding customer priorities. Design/methodology/approach Over the next year, this column will lay out a practical growth program for managers, balancing short-term moves with new-business building. Findings Growth moves fall along a spectrum of categories ranging from traditional product innovation to longer-term strategies such as taking core capabilities to new markets. Managing new growth requires an active feedback loop of constantly monitoring the progress of each initiative. Practical implications Provides managers with guidelines for growth action plans. Originality/value Of particular to strategic planners, CEOs, senior executives.
Antimicrobial Treatment of Heat Sensitive Materials by Means of Atmospheric Pressure Rf‐Driven Plasma Jet (2007)

Abstract Since several years a number of activities on the field of antimicrobial treatment by using non‐thermal plasmas are known. But although there are quite a few plasma based processes commercially available, the complexity of interaction between plasma and micro organisms prevents the breakthrough of this technology up to now. Thus plasma generation and treatment method needs to be adapted for each individual application. The aim of this work is to demonstrate the industrial applicability of plasma technological processes for medical devices. Therefore a non‐thermal plasma jet operated in argon at atmospheric pressure and driven by radio frequency (27.12 MHz) is applied to antimicrobial treatment of samples made of heat sensitive materials, such as used in medical devices. Due to its compact design and low power consumption, typical 10 W to 60 W, it is predestined for modularisation. Therefore it can be adapted to nearly any geometry such as given by medical devices to be treated. The plasma is characterised by UV/VIS optical emission spectroscopy. In order to analyse the effect of the plasma on the micro organisms (Bacillus atrophaeus spores and Escherichia coli vegetative bacteria) microbiological tests are performed. First results on lethal effects of the plasma treamtent will be discussed. (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
GQlb, a Bioactive Ganglioside that Exhibits Novel Nerve Growth Factor (NGF)Like Activities in the Two Neuroblastoma Cell Lines (1983)

To clarify the role of gangliosides in the morphological and biochemical differentiation of neuronal cell cultures, the model cell culture system represented by two neuroblastoma cell lines, GOTO and NB-1, which were established from adrenal gland and metastatic neck lymph node, respectively, was examined. We found that the total ganglioside fraction from human brain had two remarkable effects on these cell lines, which are similar to those of nerve growth factor (NGF): (a) an increase in the cell number, and (b) an increase in the neurite number and the total length of neurites. In these cases, the genuine effector in total gangliosides could not be ascribed to a possibly contaminating NGF-like protein, but rather to a particular molecular species of the gangliosides, GQ1b, which could completely replace the effector function not only qualitatively but also quantitatively. Our results provide direct evidence for the participation of gangliosides in such functions.
Elastic motion correction for cardiac PET studies (2013)

Motion in PET studies degrades image quality and introduces bias, which is critical for high resolution scanners such as mCT, mMR, and HRRT. In this work we describe and compare motion corrected cardiac studies of cardiac gating and dual (cardiac and respiratory) gating. Elastic motion information is extracted using Mass Preservation Optical Flow (MPOF), and motion correction is performed during the reconstruction process. Elastic motion corrected PET cardiac studies show less noise than individual gated images, and higher resolution than images without motion correction. Studies utilizing three different tracers (FDG, Ammonia, and Rubidium) are shown in the results.
Emerging drugs for common conditions of sleepiness: obstructive sleep apnea and narcolepsy (2015)

Both OSA and narcolepsy are conditions of sleepiness for which lifelong treatments are likely to be required. In OSA, while continuous positive airway pressure will likely remain the gold standard therapy for the foreseeable future, there is plenty of room for integrating phenotypes and variants of OSA into therapeutic strategies to lead to better, more personalized disease modification. In narcolepsy, unlike OSA, drug therapy is the current mainstay of treatment. Advances using novel mechanisms to treat targeted symptoms such as sleepiness and/or novel agents that can treat more than one symptom of narcolepsy, hold promise. However, cost, convenience and side effects remain challenges.
Comparison of chemical and functional properties of soluble leaf proteins from four plant species (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTComparison of chemical and functional properties of soluble leaf proteins from four plant speciesShuh J. SheenCite this: J. Agric. Food Chem. 1991, 39, 4, 681–685Publication Date (Print):April 1, 1991Publication History Published online1 May 2002Published inissue 1 April 1991https://pubs.acs.org/doi/10.1021/jf00004a011https://doi.org/10.1021/jf00004a011research-articleACS PublicationsRequest reuse permissionsArticle Views461Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
RETRACTED: Image Super-Resolution Algorithm Based on Dual-Channel Convolutional Neural Networks (2019)

For the image super-resolution method from a single channel, it is difficult to achieve both fast convergence and high-quality texture restoration. By mitigating the weaknesses of existing methods, the present paper proposes an image super-resolution algorithm based on dual-channel convolutional neural networks (DCCNN). The novel structure of the network model was divided into a deep channel and a shallow channel. The deep channel was used to extract the detailed texture information from the original image, while the shallow channel was mainly used to recover the overall outline of the original image. Firstly, the residual block was adjusted in the feature extraction stage, and the nonlinear mapping ability of the network was enhanced. The feature mapping dimension was reduced, and the effective features of the image were obtained. In the up-sampling stage, the parameters of the deconvolutional kernel were adjusted, and high-frequency signal loss was decreased. The high-resolution feature space could be rebuilt recursively using long-term and short-term memory blocks during the reconstruction stage, further enhancing the recovery of texture information. Secondly, the convolutional kernel was adjusted in the shallow channel to reduce the parameters, ensuring that the overall outline of the image was restored and that the network converged rapidly. Finally, the dual-channel loss function was jointly optimized to enhance the feature-fitting ability in order to obtain the final high-resolution image output. Using the improved algorithm, the network converged more rapidly, the image edge and texture reconstruction effect were obviously improved, and the Peak Signal-to-Noise Ratio (PSNR) and structural similarity were also superior to those of other solutions.
Recovery-informed Theory: Situating the Subjective in the Science of Substance Use Disorder Recovery (2019)

As recovery from substance use disorder becomes more than a mere quantifiable outcome, there exists a need to discuss and propose the underlying theoretical constructs that ultimately describe and identify the science of recovery. In this abstract undertaking, we propose an initial formulation of a grand theory of recovery science, built upon the seminal theories of recovery capital, recovery-oriented systems of care, and socioecological theory. This grand theory - labeled recovery-informed theory (RIT) - states that successful long-term recovery is self-evident and is a fundamentally emancipatory set of processes. This paper will discuss, analyze, and explore this theory as it is situated within the larger substance use, misuse, and disorder contexts. The uses, implications, and benefits of RIT as an organizing point of inquiry for recovery science are also discussed. By promoting the role of subjective recovery experience in the formulation of the study of recovery, it may be possible to summon new ideas, metrics, and strategies that can directly address substance use disorders in society. Adopting a recovery-informed understanding as follows from this grand theory may allow individual recovery and wellness trajectories to be explored, adapted, and modified to exemplify person-centered and individualized recovery strategies.
Indoor visible communication utilizing plural white LEDs as lighting (2002)

Future electric lights will be composed of white LED (light emitting diodes). Indoor wireless optical communication systems utilizing white LED lights have been proposed in our laboratory and we have been studying it. Generally, plural lights are installed in our room. Therefore, their optical path difference must be considered. In this paper, the influence of optical path difference has been investigated and two approaches for this problem are introduced. One uses OOK-RZ (on-off keying, return-to-zero) coding and the other uses optical OFDM (orthogonal frequency division multiplexing). From the results of computer simulations, we have found that these approaches are feasible for wireless optical communication systems utilizing white LED lights.
Ion control characteristics of a pair of aperture electrodes (1985)

The ion control characteristics of the electrodes are the most important factor in the ion flow printing process. The authors measure the corona current passing through the aperture electrodes and calculate the ion trajectories from the electrostatic potential near the electrodes. The data are expressed as the ion transmission rate f, which has three non-dimensional parameters relating to the electric field and aperture geometry. Printing conditions for the process are calculated using this ion transmission rate f.
Intramolecular [4+2] cycloadditions as a general strategy for alkaloid synthesis. A novel formal synthesis of lycorine (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIntramolecular [4+2] cycloadditions as a general strategy for alkaloid synthesis. A novel formal synthesis of lycorineStephen F. Martin, Chihyun Tu, Michio Kimura, and Stanley H. SimonsenCite this: J. Org. Chem. 1982, 47, 19, 3634–3643Publication Date (Print):September 1, 1982Publication History Published online1 May 2002Published inissue 1 September 1982https://pubs.acs.org/doi/10.1021/jo00140a008https://doi.org/10.1021/jo00140a008research-articleACS PublicationsRequest reuse permissionsArticle Views545Altmetric-Citations46LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
A modular and mobile system for indoor localization (2010)

The work presents a system for sensor data and complementary information fusion for localization in indoor environments. The system is based on modular sensor units, which can be attached to a person and contains various sensors, such as range sensors, inertial and magnetic sensors, a GPS receiver and a barometer. The measurements are processed using Bayesian Recursive Estimation algorithms and combined with available a priori knowledge such as map information or human motion models and constraints. The processing can be done locally, since all necessary data are available on the mobile unit. This system provides a platform for implementation, combination and evaluation of various localization principles and can be used for a variety of applications, such as indoor and outdoor pedestrian navigation, localization of other objects such as vehicles as well as robotics applications.
The PXR is a drug target for chronic inflammatory liver disease (2010)

PXR activation is anti-inflammatory in the liver and the effects of cyclosporin A in PBC disease recurrence may be mediated in part via the PXR. Since PXR activation promotes hepatocyte growth and is also anti-fibrogenic, the PXR may be an excellent drug target for the treatment of chronic inflammatory liver disease.
G protein gamma subunits contain a 20-carbon isoprenoid. (1990)

A small subset of cellular proteins are covalently modified by the addition of isoprenoid groups. These include p21ras, fungal mating factors, and nuclear lamins, which are isoprenylated at carboxyl-terminal cysteine residues with a 15-carbon farnesyl group. The similarity of the carboxyl-terminal sequences of these proteins with the alpha and gamma subunits of signal-transducing guanine nucleotide-binding regulatory proteins (G proteins) prompted examination of isoprenylation of G protein subunits. PC-12 cells were incubated with the isoprenoid precursor [3H]mevalonolactone. The beta and gamma subunits were isolated by specific association with an affinity column of immobilized alpha subunits. The gamma subunits were radiolabeled, and the tritiated lipid released from them by treatment with methyl iodide comigrated chromatographically with the 20-carbon isoprenoid geranylgeraniol. Label was not detected in G protein alpha or beta subunits. Isoprenylation of gamma subunits by the geranylgeranyl group is presumed to contribute to the association of G proteins with membranes.
Motorcycle helmet safety design research (2010)

By analyzing market research results of motorcycle helmets, this article proposes the improved motorcycle helmet safety design after discussing helmets' function, structure, materials, ergonomics, color, and many other characteristics. The design makes use of “honeycomb“ structure, solar panels and other methods to improve the safety performance of protective helmets, accomplishes motorcycle helmets safety innovation design.
Effect of Branching on Polymer Diffusion in Branched Poly(butyl methacrylate) Latex Films (2008)

Fluorescent donor- and acceptor- labeled latex particles comprised of branched poly(butyl methacrylate) (PBMA) were prepared via semicontinuous emulsion polymerization. All latex particles have similar particle size and narrow size distribution. The degrees of branching of the PBMA samples were controlled by adding various amount of bisphenol A dimethacrylate (BPDM) as a branching agent. 1-Dodecanethiol (C12−SH) was used as a chain transfer agent to prevent gel formation and control the molecular weight. The number average molecular weights of all PBMA samples are ca. 45 000 g/mol. The degrees of branching were determined by 1H NMR. Latex films were cast from a 1:1 mixture of donor- and acceptor-labeled latices. The polymer diffusion in the latex films was studied by measuring the energy transfer (ET) from the donor to the acceptor using the time-correlated single photon counting technique. Polymer diffusion rates increased with decreasing values of Tg when the latex films were annealed at 23 °C. After correcting for the effects of Tg, by comparing results at a constant T − Tg, ET data show that the PBMA with the highest degree of branching had the highest diffusivity.