gebhart/patrepeval huggingface dataset:
Reproducible operating margins on a 72 800-device digital superconducting chip (2015)

We report the design and test of Reciprocal Quantum Logic shift-register yield vehicles consisting of up to 72,800 Josephson junction devices per die, the largest digital superconducting circuits ever reported. Multiple physical layout styles were matched to the MIT Lincoln Laboratory foundry, which supports processes with both four and eight metal layers and minimum feature size of 0.5 μm. The largest individual circuits with 40,400 junctions indicate large operating margins of $\pm$20% on AC clock amplitude. In one case the data were reproducible to the accuracy of the measurement, $\pm$1% across five thermal cycles using only the rudimentary precautions of passive mu-metal magnetic shielding and a controlled cool-down rate of 3 mK/s in the test fixture. We conclude that with proper mitigation techniques, flux-trapping is no longer a limiting consideration for very-large-scale-integration of superconductor digital logic.
Acronym-Expansion Recognition and Ranking on the Web (2007)

The paper presents a study on large-scale automatic extraction of acronyms and associated expansions from Web data and from the user interactions with this data through Web search engines. We investigate three information sources for extracting and ranking acronym-expansion pairs, as provided by a large-scale search engine: the crawled web documents, the search engine logs, and the search results. We evaluate and compare the acronym-expansion pairs generated from these sources on three dimensions: (1) the precision and recall of each source; (2) the overlap and inclusion among the acronym-expansion sets; and (3) the rank-order correlation of the ordered expansion sets. Our results show that all three data sources play an important role in building a comprehensive up-to-date collection of acronym-expansion pairs.
Teaching OLE automation (1996)

The PBL approach is appropriate in any course where a project can be used.
Mathematical Foundations of Elasticity (1984)

[Preface] This book treats parts of the mathematical foundations of three-dimensional elasticity using modern differential geometry and functional analysis. It is intended for mathematicians, engineers, and physicists who wish to see this classical subject in a modern setting and to see some examples of what newer mathematical tools have to contribute.
Energy Harvesting Strategy Using Piezoelectric Element Driven by Vibration Method (2010)

This study demonstrates a method for harvesting the electrical power by the piezoelectric actuator from vibration energy. This paper presents the energy harvesting technique using the piezoelectric element of a bimorph type driven by a geared motor and a vibrator. The geared motor is a type of PWM controlled device that is a combination of an oval shape cam with five gears and a speed controller. When using the geared motor, the piezoelectric element is size of 36L×13W×0.6H. The output voltage characteristics of the piezoelectric element were investigated in terms of the displacement and vibration. When using the vibrator, the electric power harvesting is based on piezoelectric effect and piezoelectric vibrator consists of a magnetic type oscillator, a cantilever, a bimorph actuator and controllers. Low frequency operating technique using piezoelectric vibrator is very important because normal vibration sources in the environment such as building, human body, windmill and ship have low frequency characteristics. We can know from this study results that there are many energy sources such as vibration, wind power and wave power. Also, these can be used to the energy harvesting system using smart device like piezoelectric element.
Innervation patterns of PGP 9.5-positive nerve fibers within the human lumbar vertebra (2011)

Intervertebral disc injury or degeneration is a common cause of low back pain, and yet the specific source of pain remains ambiguous in many cases. Previous research indicates that the central vertebral endplate is highly innervated and can elicit pain responses to pressure. In effort to trace the origin of nerves located at the endplate, we used protein gene product 9.5 (PGP 9.5) to stain neurofibers and then quantified the spatial pattern of nerve distribution within a human L4 lumbar vertebra. The majority of nerves were adjacent to blood vessel walls, and consequently the nerve distribution closely resembled previously established vascularity patterns. We observed that the majority of nerves enter the vertebral body posteriorly, via the basivertebral foramen, and cluster in the vertebral center. These nerves follow the course of the nutrient artery, which enters the vertebral body through the basivertebral foramen, then branches toward the superior and inferior endplates. Our observations support the notion that nerves found at the central endplate could originate from sinuvertebral nerves accompanying the nutrient artery into the vertebral body. We also stained neighboring histological sections with calcitonin gene-related protein and noted significant co-localization with PGP 9.5, substantiating a nociceptive role for the nerves constituting our distribution pattern.
Cyclic Wiener filtering: theory and method (1993)

Conventional time and space filtering of stationary random signals, which amounts to forming linear combinations of time translates and space translates, exploits the temporal and spatial coherence of the signals. By including frequency translates as well, the spectral coherence that is characteristic of cyclostationary signals can also be exploited. Some of the theoretical concepts underlying this generalized type of filtering, called frequency-shift (FRESH) filtering, are developed. The theory of optimum FRESH filtering, which is a generalization of Wiener filtering called cyclic Wiener filtering, is summarized, and the theory is illustrated with specific examples of separating temporally and spectrally overlapping communications signals, including AM, BPSK, and QPSK. The structures and performances of optimum FRESH filters are presented, and adaptive adjustment of the weights in these structures is discussed. Also, specific results on the number of digital QAM signals that can be separated, as a function of excess bandwidth, are obtained.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Fast Recovery Blind Equalization for Time-Varying Channels Using “Run-and-Go” Approach (2007)

In this paper, we propose a blind adaptive equalization scheme for time-varying channels, which combines a blind algorithm based on high order statistics (HOS) and decision-directed (DD) LMS algorithm. In contrast to the ldquostop-and-gordquo algorithm , where DD-LMS adaptation is stopped for unreliable decisions, the proposed algorithm applies a blind algorithm based on HOS for the unreliable decisions. Furthermore, the region of reliable decisions is updated corresponding to the estimated signal quality. Hence, the proposed ldquorun-and-gordquo algorithm inherits MMSE performance of DD-LMS and the (re)acquisition ability of the blind algorithm. Especially, for decision feedback equalizers (DFEs) the proposed algorithm provides robust blind initialization and reacquisition ability under time varying multipath environments.
Efficacy of Fidaxomicin Versus Vancomycin as Therapy for Clostridium difficile Infection in Individuals Taking Concomitant Antibiotics for Other Concurrent Infections (2011)

Treatment with CAs compromised initial response to CDI therapy and durability of response. Fidaxomicin was significantly more effective than vancomycin in achieving clinical cure in the presence of CA therapy and in preventing recurrence regardless of CA use.
Dissecting the taxonomic heterogeneity within Propionibacterium acnes: proposal for Propionibacterium acnes subsp. acnes subsp. nov. and Propionibacterium acnes subsp. elongatum subsp. nov. (2015)

Propionibacterium acnes subsp. acnes subsp. nov. and Propionibacterium acnes subsp. elongatum subsp. nov. are described. These emanate from the three known phylotypes of P. acnes, designated types I, II and III. Electron microscopy confirmed the filamentous cell shape of type III, showing a striking difference from types I/II, which were short rods. Biochemical tests indicated that, in types I/II, either the pyruvate, l-pyrrolidonyl arylamidase or d-ribose 2 test was positive, whereas all of these were negative among type III strains. Matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) spectra, which profile mainly their ribosomal proteins, were different between these two groups. Surface-enhanced laser-desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) spectra of all phylotypes revealed a specific protein biomarker that was overexpressed in type III strains compared with types I/II only when grown aerobically. Reference strains had high whole-genome similarity between types I (>91 %) and II (>75 %), but a considerably lower level of 72 % similarity with type III. recA and gyrB sequence dendrograms confirmed the distant relatedness of type III, indicating the presence of two distinct centres of variation within the species P. acnes. On the other hand, cellular fatty acid profiles and 16S rRNA gene sequence relatedness (>99.3 %) circumscribed the species. Thus, we propose two subspecies, Propionibacterium acnes subsp. acnes subsp. nov. for types I/II and Propionibacterium acnes subsp. elongatum subsp. nov. for type III. The type strain of Propionibacterium acnes subsp. acnes is NCTC 737T ( = ATCC 6919T = JCM 6425T = DSM 1897T = CCUG 1794T), while the type strain of Propionibacterium acnes subsp. elongatum is K124T ( = NCTC 13655T = JCM 18919T).
Morphine Induces Desensitization of Insulin Receptor Signaling (2003)

Morphine analgesia is mediated principally by the micro -opioid receptor (MOR). Since morphine and other opiates have been shown to influence glucose homeostasis, we investigated the hypothesis of direct cross talk between the MOR and the insulin receptor (IR) signaling cascades. We show that prolonged morphine exposure of cell lines expressing endogenous or transfected MOR, IR, and the insulin substrate 1 (IRS-1) protein specifically desensitizes IR signaling to Akt and ERK cascades. Morphine caused serine phosphorylation of the IR and impaired the formation of the signaling complex among the IR, Shc, and Grb2. Morphine also resulted in IRS-1 phosphorylation at serine 612 and reduced tyrosine phosphorylation at the YMXM p85-binding motifs, weakening the association of the IRS-1/p85 phosphatidylinositol 3-kinase complex. However, the IRS-1/Grb2 complex was unaffected by chronic morphine treatment. These results suggest that morphine attenuates IR signaling to Akt by disrupting the IRS-1-p85 interaction but inhibits signaling to ERK by disruption of the complex among the IR, Shc, and Grb2. Finally, we show that systemic morphine induced IRS-1 phosphorylation at Ser612 in the hypothalamus and hippocampus of wild type, but not MOR knockout, mice. Our results demonstrate that opiates can inhibit insulin signaling through direct cross talk between the downstream signaling pathways of the MOR and the IR.
Resolvin D1 Improves the Resolution of Inflammation via Activating NF-κB p50/p50–Mediated Cyclooxygenase-2 Expression in Acute Respiratory Distress Syndrome (2017)

Acute respiratory distress syndrome (ARDS) is a severe illness characterized by uncontrolled inflammation. The resolution of inflammation is a tightly regulated event controlled by endogenous mediators, such as resolvin D1 (RvD1). Cyclooxygenase-2 (COX-2) has been reported to promote inflammation, along with PGE<sub>2</sub>, in the initiation of inflammation, as well as in prompting resolution, with PGD<sub>2</sub> acting in the later phase of inflammation. Our previous work demonstrated that RvD1 enhanced COX-2 and PGD<sub>2</sub> expression to resolve inflammation. In this study, we investigated mechanisms underlying the effect of RvD1 in modulating proresolving COX-2 expression. In a self-limited ARDS model, an LPS challenge induced the biphasic activation of COX-2, and RvD1 promoted COX-2 expression during the resolution phase. However, it was significantly blocked by treatment of a NF-κB inhibitor. In pulmonary fibroblasts, NF-κB p50/p50 was shown to be responsible for the proresolving activity of COX-2. Additionally, RvD1 potently promoted p50 homodimer nuclear translocation and robustly triggered DNA-binding activity, upregulating COX-2 expression via lipoxin A<sub>4</sub> receptor/formyl peptide receptor 2. Finally, the absence of p50 in knockout mice prevented RvD1 from promoting COX-2 and PGD<sub>2</sub> expression and resulted in excessive pulmonary inflammation. In conclusion, RvD1 expedites the resolution of inflammation through activation of lipoxin A<sub>4</sub> receptor/formyl peptide receptor 2 receptor and NF-κB p50/p50-COX-2 signaling pathways, indicating that RvD1 might have therapeutic potential in the management of ARDS.
Allergenic Components of Bald-Faced Hornet <i>(V. maculata)</i> Venom (1985)

Bald-faced hornet (V. maculata) venom collected by electrical stimulation was fractionated using molecular exclusion gel-filtration and ion-exchange chromatography. Four fractions were selected for in-depth analysis. These were analyzed for phospholipase, hyaluronidase and protease enzyme activities, antigenicity as measured by reaction with anti-hornet venom rabbit serum, and allergenic activity, as determined by RAST reaction with sera from hornet-sensitive patients. The results of these studies suggest that the fractions containing phospholipase, hyaluronidase and protease possess allergenic activity. In addition, there appear to be other allergenic components in hornet venom. Allergic patients differ in their reactivity to the various allergenic components in hornet venom and may have IgE antibodies to one or more of these components.
Factors influencing configuration and performance of multipurpose manned entry vehicles (1964)

Covers advancements in spacecraft and tactical and strategic missile systems, including subsystem design and application, mission design and analysis, materials and structures, developments in space sciences, space processing and manufacturing, space operations, and applications of space technologies to other fields.
Comparison of low‐molecular‐weight heparin and antithrombin versus antithrombin alone for the prevention of symptomatic venous thromboembolism in children with acute lymphoblastic leukemia (2007)

Prophylaxis with enoxaparin was safe and effective in preventing TE. Although our data are encouraging, the in vivo efficacy of combined enoxaparin and AT prophylaxis to prevent symptomatic venous TE in children with ALL should be evaluated in a prospective randomized clinical trial.
William B. Guy, MD 1917-1965 (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Dermatology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Dermatology journal
Fundamental Physics of MR Imaging (2005)

Learning the basic concepts required to understand magnetic resonance (MR) imaging is a straightforward process. Although the individual concepts are simple, there are many concepts to learn and retain simultaneously; this situation may give the illusion that learning the physics of MR imaging is complicated. It is important for the radiologist who interprets MR images to understand the methods used to create the images because image contrast specifically depends on how the image data were acquired. Initial concepts include formation of magnetic fields from electric currents in loops of wire, the resonance phenomenon, the hydrogen proton and its frequency of precession, and absorption of radiofrequency energy. These concepts can then be applied to learn about T1 and T2 relaxation and contrast and how the acquisition parameters of echo time and repetition time can be used to achieve these image contrasts. Basic pulse sequences include the spin-echo, multiecho spin-echo, turbo spin-echo, inversion-recovery, and gradient-recalled-echo sequences.
A tribute to Allen Newell—1927–1992 (1992)

No abstract available.
TD-SCDMA/HSDPA Transceiver and Analog Baseband Chipset in 0.18- $\mu\hbox{m}$ CMOS Process (2010)

A dual-band time-division synchronous code-division multiple access chipset supporting 2.8-Mb/s high-speed downlink packet access has been demonstrated in 0.18-μm CMOS technology. The receiver adjacent channel selectivity requirement for the transceiver is relaxed by utilizing a high-dynamic-range analog-to-digital converter that allows selectivity improvement in analog baseband and digital baseband. The RX chain achieves 2.8-dB noise figure, -9.4-dBm total third-order input-referred intercepted point, and 5.7% error vector magnitude (EVM). TX delivers 5.0-dBm power, 88-dB gain control, and 4.5% EVM. The TX digital communication system band noise floor is 3 dB below the standard without using a surface acoustic wave filter. Both RX and TX from-idle-to-on switching times are less than 4 μS. Two chips consume 274 and 164 mW on transmitting and receiving, respectively, under a 1.8-V power supply.
Fast handovers and context transfers in mobile networks (2001)

We describe recent work enabling fast handovers and context transfer between access routers offering Internet connectivity for mobile (often wireless) nodes. We present our framework for engineering general context transfer solutions, and a protocol which uses the framework to provide a simple yet general mechanism for carrying out context transfers during handovers. Since our mechanism operates at the network level, we expect that it will be the most expedient way to provide for seamless handovers between heterogeneous networks. We report our results which show that fast handovers with context transfer at the network layer can support uninterrupted voice over IP (VoIP). Thus, our context transfer framework will catalyze the arrival of a unified wireless telecommunications network, with voice and data connectivity anytime, anywhere. Towards that end, we describe how our results and context transfer framework relate to other work within the IETF.
Inhibition of Chemically Induced Carcinogenesis by 2-<i>n</i>-Heptylfuran and 2-<i>n</i>-Butylthiophene from Roast Beef Aroma (1994)

2-n-Butylthiophene (BT) and 2-n-heptylfuran (HF) are two of the numerous furan and thiophene containing compounds present in roast beef aroma. They have been found to induce increased activity of the detoxifying enzyme, glutathione S-transferase (GST). Since furan containing natural products that induce increased activity of GST are known to inhibit tumorigenesis in laboratory animals, the inhibitory effects of BT and HF were investigated in various target tissues. Benzo(a)pyrene-induced forestomach tumors and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumors in A/J mice were reduced by BT and HF. Their relative inhibitory effects on 1,2-dimethylhydrazine-induced aberrant crypts formation and tumorigenesis in the colon of mice indicated that BT reduced both preneoplastic and neoplastic lesions while HF did not. These results suggest furan and thiophene containing compounds may be effective inhibitors of chemical carcinogenesis in selective tissues.
Adaptive resource allocation for embedded parallel applications (2002)

Parallel and distributed computer architectures are increasingly being considered for application in a wide variety of computationally intensive embedded systems. Many such applications impose highly dynamic demands for resources (processors, memory, and communication network), because their computations are data-dependent, or because the applications must constantly interact with a rapidly changing physical environment, or because the applications themselves are adaptive. This paper presents a set of dynamic resource allocation techniques aimed at maintaining high levels of application performance in the presence of varying resource demands. It focuses on a class of applications structured as multiple pipelines of data-parallel stages, as this structure is common to many sensor-based applications. We discuss the issues involved in resource management for such applications, and present preliminary results from our implementations on Intel Paragon. Our approach uses feedback control-a real-time monitoring system is used to detect significant performance shortfalls, and resources are reallocated among the application components in an attempt to improve performance. The main contribution of this work is that it combines real-time monitoring of an application's performance with dynamic resource allocation, and focuses on practical implementations rather than simulation and analysis.
Resident-entity based simulation of batch chamber tools in 300 mm semiconductor manufacturing (2004)

We describe a resident-entity based pilot simulation study of a class of tools used in 300 mm semiconductor manufacturing known as the wets tools or the wet benches. These are batch chamber tools - they have several chambers or tanks, each of which can accommodate a batch of wafers, usually more than one lot size. We develop a simulation model for the wets processing area that is based on the resident-entity paradigm, but makes use of transient-entity-type modeling when more information needs to be tracked. Resident-entity models tend to be much faster than transient-entity simulation models that are common in semiconductor manufacturing. The model developed captures most of the internal workings of a wets tool and at the same time, models different types of tools. We used the model to evaluate the effects of scheduling policies and batching parameters on the performance of the wets process area.