gebhart/patrepeval huggingface dataset:
Recovery and reuse of marble powder by-product (2010)

The main goal of this study is to evaluate recovery and reuse of by-products coming from marble processing industries. As known, carbonate rock products have applications in most major industries, thanks to their chemical and physical characteristics. Despite this, the quarries and processing plants are littered with large amounts of waste products deriving from extraction, sawing, polishing, and water treatments. At present, no significant activities are in place to recover and reuse the ultrafine CaCO 3 dust contained in waste slurries of marble processing plants. It can be helpful to consider these calcareous particles as primary or secondary raw materials for use in other production processes. From this, a research is currently carried out in order to join this by-product with possible industrial applications. More specifically, a lot of analyses have been accomplished for the use of micronized calcium carbonate in paper, rubber, and tire industries. Recently, the possibility of using micronized stone powder to produce different commodities for the building industry has been studied. The investigation focused on the marble district area in Orosei (NE Sardinia). The data emerging from the analyses demonstrate the feasibility of these uses. What this indicates is the importance of enhancing this research field.
Studies on the Tolerance of Medium Chain Triglycerides in Dogs (1987)

Two groups of five conscious dogs received total parenteral nutrition (about 100 kcal/kg body weight per 24 hr) continuously for 96 hr (0.28 g triglycerides/kg body weight per hr, constituting more than 55% of the energy supply). The only difference between the two groups was the nature of the 20% lipid emulsion. In one group, this emulsion contained only long-chain triglycerides (LCTs), and in the other it contained a mixture (vol/vol) of medium chain triglycerides (MCTs) and LCTs. MCTs thus were given in an amount of about 30% of the total energy supplied. During infusion with the MCT/LCT mixture, C8, C10, and C12 fatty acids appeared in the total plasma fatty acids. When the infusion was stopped, the medium-chain fatty acids disappeared; those with shorter chains did so more rapidly. The plasma triglyceride clearance was faster for the MCT/LCT mixture than for the LCTs, whereas phospholipid and cholesterol clearance seemed slower for the MCT/LCT mixture. With this mixture, there was a slight increase in the plasma concentrations of ketone bodies, lactate, and pyruvate, and a slight decrease in plasma glucose. The MCT/LCT mixture was well tolerated, causing no discernible problems, and, in particular, no signs of narcosis or encephalopathy.
Wide-area visual modeling and tracking for mobile augmented reality (2012)

The vision of “Anywhere Augmentation” is to enable a ubiquitous augmented reality experience, indoors and out, by leveraging existing geographic resources and providing tools to easily map new spaces with cheap, off-the-shelf hardware. My work considers the use of panoramic datasets to provide complete and detailed environment models for accurate mobile localization and tracking. I present an end-to-end system which covers modeling, localization and tracking for AR. The implementation is demonstrated with the Apple iPad 2 as a mobile AR tablet, using a remote server for computationally heavy localization queries. 
This dissertation discusses the details of my methods and my contributions to outdoor modeling and tracking for AR. Outdoor visual modeling is improved by using the “upright” constraint, which requires that all images be aligned to a common vertical. The resulting model is used to determine the location of a mobile device by matching the camera image to the point cloud. I consider the problem of latency between the mobile device and the localization server, and present strategies to handle this latency. Continuous device localization is achieved by real-time tracking on the mobile device, which is shown to be robust to illumination change. In addition, I evaluate the relationship between modeling effort and localization performance, to determine the feasibility of in situ reconstruction of large spaces by a mobile user. The work leads to insights and future directions for pursuing a state-of-the-art “Anywhere Augmentation” system.
Image‐guided method for TLD‐based <i>in vivo</i> rectal dose verification with endorectal balloon in proton therapy for prostate cancer (2013)

Our results show that image-guided TLD-based in vivo dosimetry for rectal dose verification can be perfomed reliably and reproducibly for proton therapy in prostate cancer.
Choline biosynthesis in sheep. Evidence for extrahepatic synthesis (1987)

1. Choline production by various tissues of the sheep was measured by determining venous and arterial free choline concentrations in blood samples taken from various vessels in conscious multicannulated sheep. 2. Significant production of free choline occurred in the upper and lower body regions, and specifically in the heart, brain and hind-limb muscles of sheep, but there was no significant uptake or output of phosphatidylcholine across these tissues, as determined by arterio-venous differences. 3. In contrast, in the rat there were no significant arterio-venous differences in the concentrations of free choline or phosphatidylcholine across the hind-body. 4. Synthesis of phosphatidylcholine from endogenous phosphatidylethanolamine and S-adenosyl-L-[methyl-14C]methionine was measured in experiments in vitro using microsomal preparations from a variety of sheep and rat tissues. 5. The biosynthetic activity was highest in liver from sheep and rats, although the activity in sheep microsomal preparations was about one-quarter of that in rat microsomal preparations. 6. Microsomal preparations from sheep lung, kidney, gut epithelium, brain, heart and skeletal muscles also showed considerable biosynthetic activity, but in the rat the activity was virtually confined to the liver. 7. Overall, the results show a significant production of choline in extrahepatic tissues of the sheep, with skeletal muscle contributing some 60% of this extrahepatic activity. Thus the extrahepatic production of choline in the sheep, together with the extensive reutilization of bile choline, can explain the maintenance of the large endogenous body pool of choline in this species.
Comparison of the Impact of γ‐Oryzanol and Corn Steryl Ferulates on the Polymerization of Soybean Oil During Frying (2011)

Abstract Corn steryl ferulates (CSF), oryzanol, a combination of equal amounts of CSF and oryzanol, and ferulic acid were added to refined, bleached, deodorized, soybean oil at a concentration of 8.1–8.4 μmol/g oil, which corresponded to 0.5% (w/w) for the steryl ferulates. The rate of polymerized triacylglycerol (PTAG) formation was determined in three replicate, two‐day frying experiments using a miniature frying protocol with potato cubes. Oryzanol and ferulic acid slightly inhibited PTAG formation on the first day of frying. However, the two treatments were not significantly different from the SBO control on the second day of frying. CSF and the combination of CSF and oryzanol significantly inhibited PTAG formation on both days of frying, but the combination was slightly more effective on the second day of frying. Tocopherol degradation in SBO with added oryzanol or ferulic acid proceeded more rapidly compared to the control. However, CSF and the combination of CSF and oryzanol appeared to protect tocopherols from degradation. In addition, CSF was more stable to frying compared to oryzanol, but when CSF and oryzanol were combined, CSF protected oryzanol from degradation.
Chalcosis oculi (1998)

With exception of a Kayser-Fleischer ring of the cornea the patient presents all morphologic signs of ocular chalcosis. Although the observed patches on the central retina in ocular chalcosis are described in the literature, their nature is not known.
Application of signal enhancement by easily ionized elements in hydride generation direct current plasma atomic emission spectrometric determination of arsenic, antimony, germanium, tin, and lead (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTApplication of signal enhancement by easily ionized elements in hydride generation direct current plasma atomic emission spectrometric determination of arsenic, antimony, germanium, tin, and leadIan D. Brindle and Xiao Chun. LeCite this: Anal. Chem. 1989, 61, 10, 1175–1178Publication Date (Print):May 15, 1989Publication History Published online1 May 2002Published inissue 15 May 1989https://pubs.acs.org/doi/10.1021/ac00185a026https://doi.org/10.1021/ac00185a026research-articleACS PublicationsRequest reuse permissionsArticle Views106Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Regulatory potential of<i>n</i>-3 fatty acids in immunological and inflammatory processes (2002)

Over the last few years immunonutrition has gained increasing importance. Among other compounds lipids, especially n-3 polyunsaturated fatty acids, were shown to influence the immune response. The anti-inflammatory effects they exert can be induced by free fatty acids, triglyceride fatty acids, after incorporation into the membrane phopspholipid bilayer or following metabolism to eicosanoids. n-3 Fatty acids influence inflammatory cell activation processes from signal transduction to protein expression even involving effects at the genomic level. n-3 Fatty acid-mediated mechanisms decreased cytokine-induced adhesion molecule expression, thereby reducing inflammatory leucocyte-endothelium interactions and modified lipid mediator synthesis, thus influencing the transendothelial migration of leucocytes and leucocyte trafficking in general. Even the metabolic repertoire of specific immunocompetent cells such as cytokine release or proliferation is modified by n-3 fatty acids. Beyond this they regulate lipid homeostasis shifting the metabolic pathways towards energy supply thus optimizing the function of immune cells. Due to the regulatory impact on different processes of inflammatory and immune cell activation n-3 fatty acids provide positive effects on various states of immune deficiencies and diseases with a hyperinflammatory character, among which selected examples are presented.
Selection against the Dihydrofolate Reductase-Thymidylate Synthase ( <i>DHFR-TS</i> ) Locus as a Probe of Genetic Alterations in <i>Leishmania major</i> (1996)

The genome of the trypanosomatid protozoan genus Leishmania has been shown to undergo a number of changes relevant to drug resistance and virulence, such as gene amplification, chromosomal rearrangement, and variation in ploidy. Experimental approaches to the study of genomic changes have in some cases been limited by the fact that Leishmania cells are asexual diploids, as are some other trypanosomatids, pathogenic fungi, and cultured mammalian cells. Here we report upon a system which permits the measurement of several types of genomic change occurring at the dihydrofolate reductase-thymidylate synthase (DHFR-TS) locus. First, we show that DHFR-TS can function as a positive/negative marker. We used selection against DHFR-TS on a heterozygous line (+/HYG) to generate colonies exhibiting both loss of heterozygosity and structural mutations in DHFR-TS, permitting the first measurement of mutation frequencies in this parasite. Loss of heterozygosity occurred at a frequency ranging from 10(-4) to 10(-6) and was elevated 24-fold by treatment with gamma-irradiation, while the frequency of other events was less than 10(-6) and was increased more than 1,000-fold by nitrosoguanidine treatment. The frequency of loss of heterozygosity relative to other processes such as mutation and gene replacement has important implications for genetic variability in natural Leishmania populations and the generation of both targeted and random mutations. We also developed a protocol for null targeting of diploid cells, in which transfection of a DHFR-TS deletion construct into Leishmania cells followed by negative selection yielded parasites lacking DHFR-TS or foreign sequences. The null-targeting method can be applied to any diploid cell, at any locus for which a negative selection exists. Such marker-free auxotrophic Leishmania cells show potential as an attenuated vaccine, and the methods developed here provide a new approach for manipulating and characterizing the plasticity of the Leishmania genome.
Intrusion detection via system call traces (1997)

Unusual behavior in computer systems can be detected by monitoring the system calls being executed by programs. Analysis of the temporal ordering of these calls reveals that such anomalies are localized within traces and that normal program behavior can be described compactly using deterministic finite automata. This article presents preliminary work in analyzing system call traces, particularly their structure during normal and anomalous behavior.
Initiation and regulation of fibrinolysis in human plasma at the plasminogen activator level (1987)

The initiation and regulation of fibrinolysis has been studied by reconstitution of fibrinolytic activity in human plasma in vitro. Depletion of tissue plasminogen activator (tPA) antigen by immunoadsorption of human plasma with anti-tPA Ig Sepharose 4B leads to total loss of spontaneous fibrinolytic activity determined by lysis of a thrombin-induced clot. Addition of physiological concentrations of purified tPA to tPA-depleted plasma restores fibrinolytic activity as a function of the length of time between tPA addition and clotting. Addition of free tPA to tPA-depleted plasma followed by immediate clotting results in a high rate of fibrinolysis. In contrast, when free tPA is allowed to incubate in plasma for 10 to 60 minutes prior to clot formation, the fibrinolytic activity of tPA is gradually lost. The loss of tPA-induced fibrinolytic activity in unclotted plasma is accompanied by decreased partitioning of tPA antigen into fibrin after clotting and is kinetically correlated with the formation of a 100 kilodalton (kDa) tPA complex as demonstrated by SDS-gel electrophoresis and fibrin-agar zymography. These results suggest that free tPA is susceptible to complexation by the plasma inhibitor in the absence of a clot. Fibrin formation renders tPA relatively inaccessible to inhibition. The tPA antigen isolated from stored plasma consists mainly of 100 kDa activity in SDS-gel electrophoresis and zymography, indicating that the tPA complex is resistant to dissociation by SDS. Upon rezymography of the sliced gel, only a 60 kDa tPA activity is found, suggesting that the activity at 100 kDa is at least partly due to free tPA dissociated from the complex during the first zymography. Conversion of tPA complex to enzymatically active free tPA also occurs with brief SDS exposure followed by incubation in the presence of excess Triton X-100 or by hydroxylamine treatment. These results reconcile the apparent discrepancy of the 100 kDA inhibitor-tPA complex manifesting plasminogen activation activity during zymography. The plasma tPA- inhibitor complex is precipitated strongly by antisera against plasminogen activator inhibitors (PAIs) of human Hep G2 hepatoma and HT- 1080 fibrosarcoma cells and weakly by antiserum against bovine aortic endothelial cell PAI but not by antiserum against a placental PAI (PAI- 2) suggesting that the plasma inhibitor is immunologically related to Hep G2, HT-1080 and possibly endothedial cell PAIs. Based on the above findings, a simple model for the initiation and regulation of plasma fibrinolysis at the PA level has been formulated.
Amorphous Silicon Static Induction Transistor (1985)

A hydrogenated amorphous silicon (a-Si:H) Schottky-gate static induction transistor (SIT) is proposed and its characteristics are calculated for the case that the gap-state distribution in a-Si:H is constant near the Fermi level. It is found that an a-Si:H SIT with a gate spacing of about 5 µm can yield a sufficiently high ON/OFF current ratio of more than 10 8 when the gap-state density near the Fermi level is 5×l0 15 cm -3 eV -1 . The cut-off frequency of an a-Si:H SIT is expected to exceed a few MHz.
The Effect of the Synthetic Pentasaccharide SR 90107/ORG 31540 on Thrombin Generation Ex Vivo Is Uniquely due to ATIII-Mediated Neutralization of Factor Xa (1995)

The inhibition of thrombin generation (TG) was studied in plasma from human volunteers after single subcutaneous administrations of 4000, 8000 or 12,000 anti-Xa units (i.e., 6, 12 or 18 mg) of the synthetic pentasaccharide (SR 90107/ORG 31540) (SP). SP impaired TG in plasma for up to 18 h after injection, and the time-courses of TG and factor Xa inhibitions were similar. In untreated plasma supplemented in vitro with SP to obtain the same anti-Xa activity as in ex vivo samples, equivalent TG inhibitions were observed thus showing that no transformed SP molecules were involved in the TG inhibition ex vivo. Functional as well as immunological assay of TFPI indicated that subcutaneous injection of 12,000 anti-Xa units of SP did not induce any TFPI release, whereas under the same conditions, 13,000 IU of Fraxiparine produced a significant rise of TFPI in plasma. The plotting of TG inhibition versus SP concentration could be fitted with a good correlation (r = 0.94) to the graphical representation linking [ATIII-SP] to [SP]. These results demonstrate that following subcutaneous administration to man, SP inhibits TG ex vivo and likely in vivo exclusively through the same selective ATIII-mediated inhibition of factor Xa as the one elicited in vitro.
Dynamic Ordering and Phase Segregation in Hydrogen-Bonded Polymers (2016)

Hydrogen bonds (H-bonds) constitute highly relevant structural units of molecular self-assembly. They bridge biological and synthetic sciences, implementing dynamic properties into materials and molecules, not achieved via purely covalent bonds. Phase segregation on the other hand represents another important assembly principle, responsible for, e.g., cell compartimentation, membrane-formation, and microphase segregation in polymers. Yet, despite the expanding elegant synthetic strategies of supramolecular polymers, the investigation of phase behavior of macromolecules driven by H-bonding forces still remains in its infancy. Compared to phase segregation arising from covalently linked block copolymers, the generation of phase segregated nanostructures via supramolecular polymers facilitates the design of novel functional materials, such as those with stimuli-responsive, self-healing, and erasable-material properties. We here discuss the phase segregation of H-bonding polymers in both the solution and solid state, wherein the molecular recognition elements are based on multiple H-bonding moieties, such as thymine/2,6-diamino-pyridine (THY/DAP), thymine/diamino triazine (THY/DAT), and barbiturate/Hamilton wedge (Ba/HW) elements. The specific aggregation of a series of different H-bonding polymers in solution, both linear and dendritic polymers, bearing heterocomplementary H-bonding moieties are described, in particular focusing on the issue of phase segregation. The exploitation of H-bonded supramolecular dendrons with segregating polymer chains leads to the formation of three-phase segregated hierarchical micelles in solution, purely linking the components via H-bonds, in turn displaying a versatile spectrum of segregated morphologies. We also focus on segregation effects of H-bonded amorphous and crystalline polymers: thus the formation of nanostructures, such as disordered micelles and well-ordered body centered cubic (BCC) packed spheres from telechelic polymers bearing H-bonding moieties at the chain ends is observed. Finally, we discuss the discovery of novel functional microphase separated self-healing supramolecular architectures, illustrating dynamic and self-healing properties with an almost complete recovery of the initial mechanical performances healing within 24h at 30 °C. Collectively, our studies prove that phase segregation in H-bonding polymers is an important principle, capable to generate nanostructures and dynamic properties not achieved in covalently linked polymers. The results discussed illustrate that a rational architectural design within H-bonding polymer systems in interplay with phase segregation in both the amorphous and crystalline state opens perspectives to develop artificial supramolecular systems approaching the level of complexities and properties present in nature's biomaterials.
Electrically Controlled Drug Delivery from Biotin‐Doped Conductive Polypyrrole (2006)

A platform for controlled drug delivery using a conductive-polymer substrate has been created. Through the incorporation of biotin into the conductive polymer polypyrrole (PPy) and the subsequent attachment of the desired drug molecule (such as nerve growth factor, NGF) via a streptavidin linker, an applied potential can trigger release of the drug from the polymer surface (see figure).
A PCR primer-specific to Cylindrocarpon heteronema for detection of the pathogen in apple wood (1993)

An oligonucleotide primer (ChInt) was synthesised from the variable internally transcribed spacer (ITS) 1 region of ribosomal DNA (rDNA) of Cylindrocarpon heteronema. PCR with primers ChInt and ITS4 (from a conserved sequence of the rDNA) amplified a 470-bp fragment from several isolates of C. heteronema but not from various apple wood saprophytes. Amplification of this fragment was achieved from 1–2 pg of fungal DNA. These primers amplified a fragment of the same size from DNA extracted from cankered wood but only after impurities were removed from the DNA on a Qiagen tip-5 column. Southern hybridization analysis confirmed the 470-bp fragment from C. heteronema DNA and cankered wood to be identical.
Efficient packet monitoring for network management (2003)

Network monitoring is a vital part of modern network infrastructure management. Existing techniques either present a restricted view of network behavior and state, or do not efficiently scale to higher network speeds and heavier monitoring workloads. We present a novel architecture for programmable packet-level network monitoring that addresses these shortcomings. Our approach allows users to customize the monitoring function at the lowest possible level of abstraction to suit a wide range of monitoring needs: we use operating system mechanisms that result in a programming environment providing a high degree of flexibility, retaining fine-grained control over security, and minimizing the associated performance overheads. We present an implementation of this architecture as well as a set of experimental applications.