gebhart/patrepeval huggingface dataset:
Improved Hanning window based interpolated FFT for power harmonic analysis (2015)

Power system harmonics are inevitable in the presence of non-linear loads. The presence of harmonics has a greater impact on the terminal apparatus. Accurate analysis of Power system harmonics plays an important role to have a better mitigation. Windowed Interpolated FFT (WIFFT) based algorithms are gaining importance due to their accurate analysis. The major advantage of WIFFT based algorithms includes reduction in error due to spectral leakage and picket-fence effect. This paper represents the application of improved Hanning window based Interpolated FFT (IFFT) algorithm for harmonic analysis. The proposed algorithm is used to analyze a static simulated signal in MATLAB. The simulation results shows the effectiveness of Hanning window based IFFT compared to Hamming window based IFFT. The algorithm is also used to analyze a dynamic signal simulated in LabVIEW and its potential towards online tracking of a signal.
The Extracellular N Terminus of the Endothelin B (ETB) Receptor Is Cleaved by a Metalloprotease in an Agonist-dependent Process (2002)

The extracellular N terminus of the endothelin B (ET(B)) receptor is susceptible to limited proteolysis (cleavage at R64 downward arrow S65), but the regulation and the functional consequences of the proteolysis remain elusive. We analyzed the ET(B) receptor or an ET(B)-GFP fusion protein stably or transiently expressed in HEK293 cells. After incubation of cells at 4 degrees C, only the full-length ET(B) receptor was detected at the cell surface. However, when cells were incubated at 37 degrees C, N-terminal cleavage was observed, provided endothelin 1 was present during the incubation. Cleavage was not inhibited by internalization inhibitors (sucrose, phenylarsine oxide). However, in cells incubated with both internalization inhibitors and metalloprotease inhibitors (batimastat, inhibitor of TNFalpha-convertase) or metal chelators (EDTA, phenanthroline), the cleavage was blocked, indicating that metalloproteases cleave the agonist-occupied ET(B) receptor at the cell surface. Functional analysis of a mutant ET(B) receptor lacking the first 64 amino acids ([Delta2-64]ET(B) receptor) revealed normal functional properties, but a 15-fold reduced cell surface expression. The results suggest a role of the N-terminal proteolysis in the regulation of cell surface expression of the ET(B) receptor. This is the first example of a multispanning membrane protein, which is cleaved by a metalloprotease, but retains its functional activity and overall structure.
Improved manual and automated colorimetric determination of serum glucose, with use of hexokinase and glucose-6-phosphate dehydrogenase. (1973)

A previously reported assay for serum glucose, in which hexokinase and glucose-6-phosphate dehydrogenase were used, was improved to replace the light-sensitive phenazine methosulfate with diaphorase, providing a one-reagent system. The assay system was automated for use with standard AutoAnalyzer equipment and evaluated at 40 and 60 samples per hour with a 2:1 sample-to-wash ratio. Sensitivity, precision, accuracy, and sample interaction were quite satisfactory at both sample rates. The assay benefits from the inherent advantages of the reaction mechanism: sensitivity, specificity, NADP regeneration, and freedom from dialysis
Application of pluronic F68 for aqueous two-phase extraction of proteins. (1993)

Studies were made of the application of a block copolymer of polyethylene oxide and polypropylene oxide, Pluronic F68, to aqueous two-phase extraction of proteins. For Pluronic F68/salt systems, the effects of temperature, salt concentration and pH on the binodials and protein partitioning were studied. Pluronic F68/salt system had a region in which Pluronic F68 becomes solid in phase diagram at 25°C. Partitioning of the proteins between the two phases could be controlled by varying salt composition. Further applicability of the Pluronic F68/ammonium sulfate system was examined for the purification of monoclonal antibodies from various hybridoma culture broths. Aqueous two-phase extraction provided a simple and rapid separation and concentration method with high recovery.
Kinetic isotope effects and tunneling in cyclic double and triple proton transfer between acetic acid and methanol in tetrahydrofuran studied by dynamic proton and deuteron NMR spectroscopy (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetic isotope effects and tunneling in cyclic double and triple proton transfer between acetic acid and methanol in tetrahydrofuran studied by dynamic proton and deuteron NMR spectroscopyDetlef Gerritzen and Hans Heinrich LimbachCite this: J. Am. Chem. Soc. 1984, 106, 4, 869–879Publication Date (Print):February 1, 1984Publication History Published online1 May 2002Published inissue 1 February 1984https://pubs.acs.org/doi/10.1021/ja00316a007https://doi.org/10.1021/ja00316a007research-articleACS PublicationsRequest reuse permissionsArticle Views325Altmetric-Citations85LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
1,<i>n</i>-Rearrangement of Allylic Alcohols Promoted by Hot Water: Application to the Synthesis of Navenone B, a Polyene Natural Product (2014)

It was reported for the first time that hot water as a mildly acidic catalyst efficiently promoted 1,n-rearrangement (n = 3, 5, 7, 9) of allylic alcohols. In some cases, the rearrangement reactions joined isolated C-C double or triple bonds to generate conjugated polyene or enyne structure motifs. We used the 1,3-rearrangement reaction of an allylic alcohol in hot water as part of an attractive new strategy for construction of the polyene natural product navenone B by iterative use of a Grignard reaction, a 1,3-rearrangement of the resulting allylic alcohol, and subsequent oxidation of the rearranged product.
Switchable viscosity triggered by CO2 using smart worm-like micelles (2013)

We report two CO2-responsive aqueous solutions having switchable viscosity. The solution of sodium octadecyl sulfate and 2-(dimethylamino)ethanol forms viscoelastic worm-like micelles in the presence of CO2 but not in its absence at 60 °C. Another solution of sodium stearate and sodium nitrate has high viscosity only if CO2 is absent.
Current issues in techniques of prostate brachytherapy (1997)

Adenocarcinoma of the prostate is the most common malignancy diagnosed among men in the United States today. Brachytherapy permits conformal radiotherapy and dose escalation, and it offers the convenience of a single-day outpatient procedure which is very attractive to patients with a busy life-style. The reported potency preservation rates with brachytherapy are superior to both external beam radiation therapy (EBRT) and surgery. The older retropubic techniques have been replaced by ultrasound or CT-guided transperineal techniques. Prostate brachytherapy may be temporary or permanent, and the planning techniques for either approach are similar. This review briefly discusses the advantages and limitations of each. Temporary techniques may be used with low dose rate or high dose rate applications. The basic steps include assessing prostate volume by any diagnostic modality (CT or ultrasonography), determining total activity needed to encompass the gland and deliver the appropriate minimum peripheral dose, and determining the pattern of placement of the seeds within the gland. Preplanning may be done either by ultrasound or by CT. The operative technique requires the visualization of the prostate in three dimensions and is performed using combination of ultrasound and fluoroscopy or fluoroscopy in two axes. The New York Hospital technique employs CT-based preplanning along with ultrasound and fluoroscopy during the operative procedure. Special circumstances that necessitate neoadjuvant hormonal therapy include interference from the pubic arch and large volume glands. An analysis of patients with stage T2a disease treated at the New York Hospital-Queens, from 1990-1995, reveals an actuarial clinical freedom from relapse of 79% at 5 years and a 5-year biochemical freedom from relapse of 64% which is comparable to that reported for similar risk groups of disease by other centers. Potency is preserved in greater than 80% of patients in our series. Patient selection criteria include the pre-treatment prostate-specific antigen (PSA) level, tumor grade (Gleason), stage of disease, and presence or absence of bilateral positive biopsies and/or perineural invasion. Based on our review of the literature and our clinical results, we have divided patients with prostate cancer into good, intermediate and poor risk groups. We recommend brachytherapy as the sole procedure for good risk patients, and a combination of external beam radiation therapy (EBRT) and brachytherapy for the intermediate risk group. Future avenues for research include a search for improved imaging techniques and possibly newer isotopes. Semin. Surg. Oncol. 13:444-453, 1997. © 1997 Wiley-Liss, Inc.
Quantized Iterative Hard Thresholding: Bridging 1-bit and High-Resolution Quantized Compressed Sensing (2013)

In this work, we show that reconstructing a sparse signal from quantized compressive measurement can be achieved in an unified formalism whatever the (scalar) quantization resolution, i.e., from 1-bit to high resolution assumption. This is achieved by generalizing the iterative hard thresholding (IHT) algorithm and its binary variant (BIHT) introduced in previous works to enforce the consistency of the reconstructed signal with respect to the quantization model. The performance of this algorithm, simply called quantized IHT (QIHT), is evaluated in comparison with other approaches (e.g., IHT, basis pursuit denoise) for several quantization scenarios.
Meeting the neeh of library trade exhibitors. A handbook for exhibition organisers. 1991 12 pp. Prepared by The Association of Subscription Agents. Available free of charge from The Secretary, Association of Subscription Agents, Thames Gardens, Charlbury. Oxon OX7 3QH. (1992)

people concerned with customer service, marketing and staff selection.
Reduced order modeling for clearance control in turbomachinery (2016)

Finite element models (FEMs) are extensively used in the design optimization of utility scale steam turbines. As an example, by simulating multiple startup scenarios of steam power plants, engineers can obtain turbine designs that minimize material utilization and at the same time avoid the damaging effects of large thermal stresses or rubs between rotating and stationary parts. Unfortunately, FEMs are computationally expensive and only a limited amount of simulations can be afforded to get the final design. For this reason, numerous model reduction techniques have been developed to reduce the size of the original model without a significant loss of accuracy. When the models are nonlinear, as is the case for steam turbine FEMs, model reduction techniques are relatively scarce and their effectiveness becomes application dependent. Although there is an abundant literature on model reduction for nonlinear systems, many of these techniques become impractical when applied to a realistic industrial problem. This paper focuses in a class of nonlinear FEM characteristic of thermo-elastic problems with large temperature excursions. A brief overview of popular model reduction techniques is presented along with a detailed description of the computational challenges faced when applying them to a realistic problem. The main contribution of this work is a set of modifications to existing methods to increase their computational efficiency. The methodology is demonstrated on a steam turbine model, achieving a model size reduction by four orders of magnitude with only 5% loss of accuracy with respect to the full order FEMs. These practical implementations enable the calculation of multiple additional design scenarios.
Computer-aided redesign of VLSI circuits for hot-carrier reliability (1996)

In this paper, a computer-aided design system for CMOS VLSI circuit hot-carrier reliability estimation and redesign is presented. The system first simulates a circuit to determine the critical transistors that are most susceptible to hot-carrier effects (HCEs). It then estimates the impact of HCE on circuit performance and employs a combination of design modification strategies to eliminate HCE-induced performance degradation. Two criteria are used to evaluate HCE degradation. The first criterion is the estimation of local damage in each transistor, which indicates the possibility of failure of individual devices. The second criterion is the global degradation of the circuit, namely the increase of delay in digital circuits. If either criterion exceeds a user-specified limit, several alternative circuit redesign strategies can be chosen by the user from a suggested menu. Based on this choice, the system will automatically redesign the critical parts of the circuit to improve circuit performance. The advantages and disadvantages of these alternative redesign strategies are also compared.
Establishing PCI compliance using formal verification: a case study (2002)

This paper presents a case study in the practical application of formal verification. Specifically, we describe our experience in applying the formal verification technique of symbolic model checking to the verification of PCI bus bridges. During the last 2 years, we have used symbolic model checking to verify more than 12 hardware designs, including a number of PCI bus bridges. This use of formal verification has led to the better understanding of formal verification capabilities and the establishment of formal verification techniques as a standard verification tool in the Haifa Design Group at IBM's Haifa Research Laboratory. More than 5 PCI bus bridge designs have been verified using formal verification, including a design in which formal verification was used to do all checks at the unit level. A PCI bus bridge design that was verified with formal verification was announced as an IBM product and became available to customers after a single tape-out.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Old age and anti-cytomegalovirus immunity are associated with altered T-cell reconstitution in HIV-1-infected patients (2011)

The present findings indicate that HIV-1 infection amplifies the effect of age on naive T-cell levels, and highlight the constraint on the capacity of treated patients to reconstitute their CD4(+) T-cell compartment due to age and CMV co-infection.
Bundling the Web: HTTP over DTN (2006)

Mobile users traveling by car, bus, or train usually experience varying connectivity characteristics while they are on their way, including unpredictable (loss of) network access, changes in a data rate, and the like. In short, they operate in a challenged networking environment that is not well suited for many Internet applications. While different approaches have been developed to specifically mitigate (short-term) disconnections while at least partly preserving the end-to-end notion of such applications, Delay-tolerant Networking (DTN) takes a different approach by relying exclusively on asynchronous communications. While this fits well with the mobile user connectivity, particularly interactive applications (such as web access) are affected by the lack of synchronous endto-end interaction. In this paper, we present protocol mechanisms for running HTTP-over-DTN as well as a system architecture for incremental deployment, and we report on findings from measurements performed with our prototype implementation.
Indexing techniques for historical databases (2003)

Two indexing structures based on R-trees are proposed for historical data, which can span magnetic disk and optical disk media. The performance of these indexes is compared to that of two other indexing candidates that are each contained entirely on one medium. Test results indicate that the proposed indexes perform well when compared to an index that is contained entirely on optical disk. >
A wide-band tuning system for fully integrated satellite receivers (1998)

The building blocks for a low-power tuning system that reduces the phase noise of integrated VCO's are described. The multimodulus prescaler, the phase frequency detector, and the wide-band charge pump have been integrated in a standard bipolar technology with 9-GHz n-p-n transistors and 200-MHz p-n-p transistors. The maximum input frequency of the multimodulus prescaler is 3.2 GHz, the maximum reference frequency of the phase frequency detector is 380 MHz, and the 3-dB bandwidth of the charge pump is 41 MHz at a reference frequency of 300 MHz. The achieved performance enables the use of fully integrated VCO's with relatively high phase noise for reception of satellite digital signals.
Daptomycin inoculum effects and mutant prevention concentration with Staphylococcus aureus (2007)

Inoculum effects on MPC can be reduced by measurement with low-density (large volume) liquid bacterial cultures. Retesting putative mutants for susceptibility can be important: stable mutants having genetic variations in the mprF gene were recovered from liquid medium, but not from agar. Daptomycin MPC with S. aureus was below minimal plasma drug concentration with approved doses, which is consistent with resistance to daptomycin arising rarely.
Flip-chip bonded 0.85-μm bottom-emitting vertical-cavity laser array on an AlGaAs substrate (1996)

We report high-performance 0.85-μm bottom-emitting vertical-cavity surface-emitting lasers (VCSELs) on an AlGaAs substrate with 2.1 mA threshold current density 4.2 mW maximum output power, 11.7% power conversion efficiency and a maximum operating temperature of 130/spl deg/C. We also demonstrate a flip-chip bonded 0.85-μm bottom-emitting VCSEL array, and confirm all pixels across the 8×8 VCSEL array operate at a f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> dB bandwidth of 2.6 GHz at only 4.2 mA.
RAMPTM: A Rapid, Quantitative Whole Blood Immunochromatographic Platform for Point-of-Care Testing (1999)

The Rapid Analyte Measurement Platform (RAMP™) is an enabling immunodiagnostic platform for quantitative analysis of a wide variety of analytes. Consisting of an immunochromatographic strip in a disposable cartridge and a scanning dual wavelength fluorescence reader, RAMP takes advantage of the inherent simplicity of lateral flow immunochromatography while providing a quantitative measurement of analyte concentration. Using 2–3 drops of whole blood, a test can be completed in 5 min by placing the blood on the cartridge and placing the cartridge in the fluorescence reader. No training or sample measurement is needed. The system has a low manufacturing cost and a short development time per assay. A patent was issued on the system in the US in May 1998 (1).

The criteria for point-of-care testing (2) are affordable cost, a disposable device, and/or minimal maintenance and minimal technical expertise required to perform tests. The sample should be whole blood, low volume, unmetered, and applied directly into the instrument or disposable. There needs to be a simple “goof-proof” strategy for recording collection time and result reporting, a simple strategy for calibration and quality control, data transfer capability compatible with the laboratory or hospital information system and a positive identification and specimen-tracking strategy that eliminates specimen identification error. …
Electrical Stimulation of Spared Corticospinal Axons Augments Connections with Ipsilateral Spinal Motor Circuits after Injury (2007)

Activity-dependent competition shapes corticospinal (CS) axon outgrowth in the spinal cord during development. An important question in neural repair is whether activity can be used to promote outgrowth of CS axons in maturity. After injury, spared CS axons sprout and make new connections, but often not enough to restore function. We propose that electrically stimulating spared axons after injury will enhance sprouting and strengthen connections with spinal motor circuits. To study the effects of activity, we electrically stimulated CS tract axons in the medullary pyramid. To study the effects of injury, one pyramid was lesioned. We studied sparse ipsilateral CS projections of the intact pyramid as a model of the sparse connections preserved after CNS injury. We determined the capacity of CS axons to activate ipsilateral spinal motor circuits and traced their spinal projections. To understand the separate and combined contributions of injury and activity, we examined animals receiving stimulation only, injury only, and injury plus stimulation. Both stimulation and injury alone strengthened CS connectivity and increased outgrowth into the ipsilateral gray matter. Stimulation of spared axons after injury promoted outgrowth that reflected the sum of effects attributable to activity and injury alone. CS terminations were densest within the ventral motor territories of the cord, and connections in these animals were significantly stronger than after injury alone, indicating that activity augments injury-induced plasticity. We demonstrate that activity promotes plasticity in the mature CS system and that the interplay between activity and injury preferentially promotes connections with ventral spinal motor circuits.
Flexible terahertz fiber optics with low bend-induced losses (2007)

We developed a metal hollow waveguide as a flexible delivery medium of terahertz waves. Theoretical evaluation shows that a metal waveguide mainly supports TE modes and that the TE11 mode shows a high coupling coefficient to linearly polarized light. Also the TE11 mode brings less mode conversion to high-order modes than the TE01 mode giving the lowest loss. We measured transmission losses in the terahertz region of hollow waveguides with inner silver coating; the losses were ∼7.5-8dB/m at the wavelengths from 190-250μm for waveguides with an inner diameter of 1mm. These losses coincide well with theoretical ones, and this shows that in these waveguides, the TE11 mode is dominant when a linearly polarized beam is launched into them. The waveguides are flexible because we use a thin-wall glass capillary as the base tubing. Our experiment revealed low additional losses due to bending even when complicated bends were applied to the waveguides. The metal-coated hollow fiber with an inner diameter of 1mm is sufficiently small and flexible for use in endoscopic applications.