gebhart/patrepeval huggingface dataset:
ve Analysis of Linear Multiuser Detectors for Fading Multipath Channels (1994)

In this paper, we compare two linear multiuser receivers for synchronous CDMA frequency-selective Rayleigh fading channels. The first receiver consists of a bank of matched filters followed by a linear transformation and an optimal combiner for each user. The second consists of a bank of‘ RAKE receivers followed by a linear transformation. We consider receivers for both coherent and differentially coherent PSK demodulation. While the conventional singleuser receiver’s performance is severely limited by near-far effects in the multiuser environment, both of these multiuser receivers mitigate the near-far problem and provide significant performance gains for moderate to high SNRs. It is shown that the second receiver has a uniformly lower error rate than the first and that its performance gains relative to the first increase as the number of users and received multipaths increases.
Measu rements of the Combusting Flow in a Pulse Combustor (1987)

Abstract Abstract-Although pulse combustion devices exhibit a high thermal efficiency and low pollutant emission when used in heating applications, broad application of these heating devices has been limited because of a lack of understanding of the fundamental controlling physical and chemical processes. Thi s paper reports the results of an experimental investigation of the effects of changing mean equivalence ratio and mass loading on the fluid dynamics in the combustion chamber of a pulse combu stor. The experimental investigation used schlieren photography for flow visualization, a two-color laser Doppler velocimeter (LOY) for velocity measurements, OH* chemiluminescence for burning rate information, thermocouples for temperature measurements, and pressure transducers for time-resolved pres sure measurements as diagnostic tools. A reasonably complete mapping of the combu stion-fluid dynamics in the combustion chamber has been performed. Results from these investigations indicate the following: (a) residual combustion process serves as the ignition source of the next combustion cycle; (b) the combustor is controlled by a two-fold mixing process (one of mixing between reactants, and one between cold reactants and hot products); and (c) the combu stor operates in a stratified charge mode.
Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53 (1998)

The p16(INK4a)-cyclin D-retinoblastoma tumor suppressor pathway is disrupted in most human cancers, and it has been suggested that the subsequent release of E2F transcription factors from inhibitory complexes may be a key event in tumor development. We described recently the generation of transgenic mice with E2F1 gene expression targeted to squamous epithelial tissues by a keratin 5 (K5) promoter. In the present study, K5 E2F1 transgenic mice were crossed with p53 null mice to examine functional interactions between E2F1 and p53 in vivo. We find that E2F1-induced apoptosis of epidermal keratinocytes is reduced in K5 E2F1 transgenic mice lacking p53, whereas E2F1-induced hyperproliferation is unaffected by p53 status. We also find that K5 E2F1 transgenic mice heterozygous or nullizygous for p53 develop spontaneous skin carcinomas, which normally are rare in p53-deficient mice. The timing of tumor development correlates with the level of E2F1 transgene expression and the status of p53. In primary transgenic keratinocytes, the major change in E2F1 DNA-binding activity is the generation of a complex also containing the retinoblastoma tumor suppressor protein. Nevertheless, the expression and associated kinase activity of cyclin E, a known target for E2F transcriptional activity, is elevated significantly in K5 E2F1 transgenic keratinocytes. These findings firmly establish that increased E2F1 expression can contribute to tumor development and suggest that p53 plays an important role in eliminating cells with deregulated E2F1 activity.
Antihyperlipidemic Effect of Curcumin and Tetrahydrocurcumin in Experimental Type 2 Diabetic Rats (2007)

Hyperlipidemia is an associated complication of diabetes mellitus. In the present study, we investigated the effect of tetrahydrocurcumin (THC), one of the active metabolites of curcumin on lipid profile in streptozotocin (STZ)-nicotinamide-induced diabetic rats. THC 80 mg/kg body weight was orally administered to diabetic rats for 45 days, resulting in a significant reduction in blood glucose and a significant increase in plasma insulin in diabetic rats, which proved that THC possess an antidiabetic effect. THC also caused a significant reduction serum and liver cholesterol, triglycerides, free fatty acids, phospholipids, HMG CoA reductase activity, very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) cholesterol levels. The decreased serum high-density lipoprotein (HDL) cholesterol in diabetic rats was also reversed toward normalization after the treatment. These biochemical observations were supplemented by histopathological examination of liver section. The effect was compared with curcumin (80 mg/kg body weight). The results showed that THC had antihyperlipidemic action in control and experimental diabetic rats. The antidiabetic and antihyperlipidemic effects of THC are more potent than those of curcumin at the same dose.
Analysis of Decision-Directed Equalizer Convergence (1980)

Digital data signals are usually equalized by passing samples of the received signal through an adaptive equalizer consisting of a tapped delay line having adjustable coefficients (tap weights). The equalizer tap weights are adjusted by starting the transmission with a short training sequence of digital data known in advance by the receiver. This paper analyzes the situation when the known training sequence is replaced by a sequence of data symbols estimated from the equalizer output and treated as known data. Such procedures are called “decision-directed” startup. With a known training sequence, the “least-mean-square” adjustment algorithm corresponds mathematically to searching for the unique minimum of a quadratic “error” surface whose unimodal nature assures convergence. In decision-directed startup, by contrast, the use of estimated and unreliable data changes the error surface into a multimodal one so that complex behavior may result. We describe the nature of the error surfaces for binary and four-level transmission, thereby gaining insight into convergence problems. The most significant conclusion is that a poor choice for the initial tap settings may result in the taps converging to an undesirable setting. We show that, because of finite step-size effects, fluctuations are significant at the undesired settings and cause the spurious capture to have a long, but finite, duration. Finally we provide information on stability, convergence times, and lifetimes and their relation to the adaptation parameter (step size).
Multipole method for microstructured optical fibers I Formulation (2002)

We describe a multipole method for calculating the modes of microstructured optical fibers. The method uses a multipole expansion centered on each hole to enforce boundary conditions accurately and matches expansions with different origins by use of addition theorems. We also validate the method and give representative results.
A pulsed field gradient NMR study of self-diffusion in a polydisperse polymer system: dextran in water (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA pulsed field gradient NMR study of self-diffusion in a polydisperse polymer system: dextran in waterPaul T. Callaghan and D. N. PinderCite this: Macromolecules 1983, 16, 6, 968–973Publication Date (Print):June 1, 1983Publication History Published online1 May 2002Published inissue 1 June 1983https://pubs.acs.org/doi/10.1021/ma00240a028https://doi.org/10.1021/ma00240a028research-articleACS PublicationsRequest reuse permissionsArticle Views726Altmetric-Citations71LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
OFDM space-time trellis-coded MIMO systems with experimental results (2003)

Multi-Input Multi-Output (MIMO) systems have been shown to provide extremely high capacity in non-line-of-sight channels. Using Space-Time Trellis Coded vector transmission, this paper shows that Maximum Likelihood Joint Detection (MLJD) receivers provide substantial improvements over Layered Space Time (LST) approaches. It is shown that in full-rank channels, the MLJD approach provides significant SNR improvement over LST techniques. It is also shown that an MLJD receiver is much more robust in reduced rank channels. These improvements come at the cost of high computational complexity at the receiver. Hybrid approaches allow complexity to be reduced by applying ML techniques to groups of transmit antennas, rather than all transmit antennas. Methods of performing this grouping based on channel conditions is presented and shown to provide a means of smoothly trading complexity for performance. Simulations and over-the-air measurements are presented that compare various MIMO receiver techniques.
QUALITY OF HIGHER EDUCATION IN ROMANIA (2013)

We must admit that now is the time to adopt few vigorous actions for identifying and stimulate the academic quality, where it exists, and to stimulate, guide and improve the quality where is necessary. Otherwise, we preserve us in a state of amiable self- complacency, which risks to sank us into a homogeneousness as uniform as devoid of perspective and competiveness. But out of this situation is in strong relationship with increasing public funding for the higher education and with solving the economic and social problems that Romania has. For solving these problems higher education has to contribute not only by fulfilling its traditional duties, but also with ideas debated in a public space as large as possible. University subjective space associated to quality seems to be a crowded one with contradictions and gaps between students and teachers guidelines. And these endogenous gaps of university system are transmitted in its relations with the outside labor market. To a public and academic space saturated of gaps and divergences corresponds another state of confusion concerning the construction standards and assurance of academic quality. If we do not introduce in the system and in the universities large and rapid adjustments, we risk to have in the future too less and less efficient universities, more and more diplomas, less and less professional individual competences and finally, we risk to deal with a chronic lack of European competiveness.
Partial nephrectomy with a combined CO<sub>2</sub> and Nd:YAG laser: Experimental study in pigs (1994)

Twenty-eight partial nephrectomies were performed on nine pigs with a simultaneous, coaxial CO2-Nd:YAG laser at power settings of 20 W and 40 W, or with a steel scalpel. A vascular pedicle clamp was used without renal cooling. The time for hemostasis was 4.5 +/- 3.2 min (mean +/- SD) with the laser and 6.4 +/- 2.5 min with the steel scalpel (P = 0.064). There was no difference in the total operation time (10.4 +/- 3.5 min with the laser vs. 11.0 +/- 3.2 min with the steel scalpel, P = 0.470). The mean blood loss with the laser was 17.5 +/- 6.7 g and 22.1 +/- 15.2 g with the steel scalpel (P = 0.299). The number of ligatures needed for complete hemostasis was 2.9 +/- 2.1 with the laser and 5.0 +/- 2.3 with the steel scalpel (P = 0.011). The average thermal damage was 0.23 +/- 0.10 mm. It is concluded that the simultaneous CO2-Nd:YAG laser method can be used in partial nephrectomy and it offers better hemostasis than the conventional technique. Further studies with different power levels are needed.
The selective muscarinic M1 agonist AF102B decreases levels of total A? in cerebrospinal fluid of patients with Alzheimer's disease (2000)

beta-Amyloid (Abeta) deposits in diffuse and compact senile plaques in the brain are one of the defining histopathological features of Alzheimer's disease (AD). Preventing Abeta deposition is a goal of drug therapy for AD, because excessive amounts of Abeta may be toxic to neurons. In preclinical studies, activation of the muscarinic M1 receptor subtype inhibited Abeta secretion from cultured cells. To determine whether a similar sequence occurs in human beings, we administered the selective M1 agonist AF102B to 19 AD patients and measured total Abeta (Abeta(total)) levels in cerebrospinal fluid (CSF) before and during treatment. Abeta(total) levels in CSF decreased in 14 patients by 22%, increased in 3 patients, and were unchanged in 2 patients; the overall decrease in the group as a whole was statistically significant. To test the specificity of the M1 effect, we also measured the relative changes in Abeta(total) levels in CSF during treatments in separate sets of AD patients with the acetylcholinesterase inhibitor physostigmine or the anti-inflammatory drug hydroxychloroquine. CSF Abeta(total) levels did not change significantly in the 9 AD patients in the physostigmine protocol or in the 10 AD patients in the hydroxychloroquine study. These data provide evidence that the activation of M1 receptors reduces Abeta levels in the CSF of AD patients. If this effect also occurs in brain, M1 agonists may have long-term therapeutic benefits by lowering amyloid in AD.
Effect of Organic Soil Amendments on the Rhizoctonia Disease of Snap Beans<sup>1</sup> (1959)

Synopsis Some correlation was found between numbers of rhizosphere fungi and ratios of bacteria to streptomycetes in the rhizosphere with disease severity. Protection imparted by amendments varied with time after incorporation.
Addition of Either Lonidamine or Granulocyte Colony-Stimulating Factor Does Not Improve Survival in Early Breast Cancer Patients Treated With High-Dose Epirubicin and Cyclophosphamide (2003)

EC is active and well tolerated in patients with early breast cancer. The addition of LND or G-CSF does not improve DFS or OS.
Alternate substrate inhibitors of an .alpha.-chymotrypsin: enantioselective interaction of aryl-substituted enol lactones (1990)

Four enol lactones, bearing phenyl or 1-naphthyl substituents on the alpha or beta positions [3-phenyl-6-methylenetetrahydro-2-pyranone (alpha Ph6H, IIc), 3-(1-naphthyl)-6-methylenetetrahydro-2-pyranone (alpha Np6H, IId), 4-phenyl-6-methylenetetrahydro-2-pyranone (beta Ph6H, IIIc), and 4-(1-naphthyl)-6-methylenetetrahydro-2-pyranone (beta Np6H, IIId)], available as pure R and S enantiomers, have been studied as alternate substrate inhibitors of chymotrypsin. Kinetic constants for substrate binding (Ks) and acylation (ka) were determined by a competitive substrate assay, using succinyl-L-Ala-L-Ala-L-Pro-L-Phe p-nitroanilide; the deacylation rate constant (kd) was determined by the proflavin displacement assay. All lactones undergo rapid acylation (ka varies from 17 to 170 min-1) that shows little enantioselectivity; there is, however, pronounced enantioselectivity in substrate binding for three of the lactones [Ks(R/S) = 40-110]. In each case it is the enantiomer with the S configuration that has the higher affinity. In all cases, deacylation rates are slow, and in two cases, acyl enzymes with half-lives of 4.0 and 12.5 h at pH 7.2, 25 degrees C, are obtained (for beta Ph6H and alpha Np6H, respectively). In these cases, high deacylation enantioselectivity is observed [kd(S/R) = 60-70], and the lactone more weakly bound as a substrate (R enantiomer) gives the more stable acyl enzyme. Two hypotheses, involving hindrance of the attack of water or an exchange of the ester and ketone carbonyl groups in the acyl enzyme, are advanced as possible explanations for the high stability of these acyl enzymes.
Investigation of digital alloyed AlInSb metamorphic buffers (2018)

Al1-xInxSb metamorphic step-graded buffers with Al0.6In0.4Sb terminal layers, designed to serve as a virtual substrate to support integrated InAs0.5Sb0.5 long-wave infrared absorber layers, were grown on GaSb wafers via molecular beam epitaxy. Two different structural profiles were used to define the effective composition of each buffer step: one based on digital alloys (1 nm period, ∼1.6 unit cells) and the other based on short period superlattices (10 nm period, ∼16 unit cells). Characterization via optical Nomarski microscopy, x-ray diffraction reciprocal space mapping, and transmission electron microscopy indicates that the digital alloy based structure behaves similar to that expected for a conventional bulk ternary alloy based structure, while the short period superlattice structure exhibits significantly hindered relaxation within the buffer layers.
A penetration analysis of a Burroughs Large System (1981)

A penetration analysis of a Burroughs Large System is described and a fundamental flaw allowing total penetration is discussed. Specific aspects examined include File Security, Resource Limits, Accounting Methods, and Disruptions.
The Use and Abuse of Practice Profiles (1994)

Once upon a time doctors had nearly complete professional autonomy. If they completed their training, were licensed by the state, and were certified by a professional board, they were assured the respect and trust of the public, and virtually no one kept track of their professional performance. What a difference a few decades make! Today, doctors' everyday decisions are regularly scrutinized, monitored, and regulated, and their judgments about individual patients can be overturned by nameless employees of third-party payers. Many physicians are concerned that recent approaches to quality control, such as practice guidelines and appropriateness studies, will regiment them even . . .
Female Uroloev EPIDEMIOLOGY OF INTERSTITIAL CYSTITIS: A POPULATION BASED STUDY (1999)

Purpose: Interstitial cystitis is a chronic and debilitating syndrome but surprisingly little is known about its epidemiology. This study was designed to estimate the prevalence of interstitial cystitis among women in the United States. Materials and Methods: Female participants in the Nurses’ Health Study (NHS) I and I1 (184,583) were asked by mailed questionnaires whether they had ever been diagnosed with interstitial cystitis. We requested and reviewed medical records of women self-reporting interstitial cystitis. The accuracy of self-reports was evaluated using standardized criteria. Results: Among the 93,428 women who responded to the NHS I1 questionnaire and 91,155 women who responded to the NHS I questionnaire 1,354 (1.4%) and 357 (0.4%), respectively, self-reported interstitial cystitis. Based on medical record review 63 cases of interstitial cystitis were confirmed in NHS I1 and 47 in NHS I. The prevalence of interstitial cystitis was 67/100,000 women in NHS I1 and 52/100,000 in NHS I. There was no substantial variation in prevalence by age. Conclusions: The Prevalence of interstitial cystitis in the United States is more than 50% greater than previously reported and %fold greater than that reported in Europe. Interstitial cystitis is a chronic debilitating syndrome characterized by irritative voiding symptoms, suprapubic and/or pelvic pain and sterile, cytologically normal urine.’ Patients with interstitial cystitis may experience the need to void as frequently as every 30 minutes during the day and several times at night. Diagnosis of interstitial cystitis should be considered in the presence of symptoms, characteristic bladder findings on cystoscopy and the absence of another more clearly defined disease.’ Surprisingly little is known regarding the epidemiology. Interstitial cystitis occurs 6 to 11 times more commonly among women than men, and has been reported in pediatric, middle-aged and elderly patients. ’ None of the 3 previously published studies with estimates of prevalence was truly population based.2-4 Estimates have ranged from 18.6/100,000 women older than 20 years in Finland3 to approximately twice that in the United States.2 To estimate the prevalence of interstitial cystitis in the United States we performed a population based study among 184,583 participants in the Nurses’ Health Study (NHS) I and 11.
Photonic integration technology without semiconductor etching (2003)

Monolithic device integration is more and more essential for the realisation of micro and optoelectronic circuits, which can fulfil complex functions with higher performances. The most prevalent approach in the fabrication of photonic integrated circuits (PICs) is the butt-coupling. This can be done in one step by Selective Area Growth (SAG) carried out by Metalorganic Vapour Phase Epitaxy (MOVPE) or by localised selective regrowth by Chemical Beam Epitaxy (CBE). The former technique inconvenient is that the structures of the devices cannot be quite different, especially, if one of them should be doped, the others will be doped as well. The latter method needs one epitaxial step for each integrated structure and requires several etching steps, which can deteriorate the performances of the regrown devices. This study proposes a new procedure to integrate several devices without any etching step.
A New, Safety-Oriented, Integrated Drug Administration and Automated Anesthesia Record System (2001)

Traditional methods of drug administration and record keeping in anesthesia are relatively error prone. By using sound principles of systems design and human factors psychology, we have designed and deployed a system with the aim of improving patient safety by facilitating correct drug administration and accurate anesthesia record making.
Development of aspirin resistance in persons with previous ischemic stroke. (1994)

The antiplatelet (and presumably the antithrombotic) effect of a fixed dose of ASA is not constant over time in all individuals. The mechanisms by which increased dosage requirement or ASA resistance develops and the clinical significance of this development are currently undefined.
Imaging the local electrical properties of metal surfaces by atomic force microscopy with conducting probes (1996)

A promising technique capable of performing localized resistance measurements over a surface is presented using a modified commercial atomic force microscope with a conducting probe. Its overall purpose is to obtain simultaneous cartographies of surface roughness and local resistance within a given microscopic area of a sample with nanometer scale resolution. Although an elaboration of suitable probes remains an ongoing problem, convincing images of some metal surfaces that reveal occasionally surprising features have already been obtained. Calculations performed from measurements have allowed us to clarify the mechanical nature of the tip/surface nanocontact and hence to determine the most probable transport process according to the range of resistance considered.