gebhart/patrepeval huggingface dataset:
PRIVACY PRESERVING SENSITIVE UTILITY PATTERN MINING (2013)

Data mining services require accurate input data for their results to be meaningful, but privacy concerns may influence users to provide spurious information. The problem of privacy-preserving data mining has numerous applications in homeland security, medical database mining, and customer transaction analysis. The main feature of the most PPDM algorithms is that they usually modify the database through insertion of false information or through the blocking of data values in order to hide sensitive information. In this paper, we have incorporated the privacy preserving concept into the previously developed weighted utility mining approach. In this, we have presented an efficient algorithm for mining of privacy preserving high utility item sets by considering the sensitive item sets. The algorithm comprise of three major steps to attain the aim of our research includes, 1) Data sanitization, 2) Construction of sensitive utility FP-tree and, 3) Mining of sensitive utility item sets. The experimentation has carried out using real as well as the synthetic dataset and the performance of the proposed algorithm is evaluated with the aid of the evaluation metrics such as Miss cost and Database difference ratio.
Electrodeless Measurement of Resistivities over a Very Wide Range (1967)

Resistivity of electronic conductors, from metals to semi-insulators, is determined from the change in grid current of a high frequency oscillator owing to the loading resulting from eddy currents in the sample. The signal appears as a pulse when the sample is dropped through the oscillator tank coil; greater amplification can be used than in previous eddy current methods where the sample was stationary during measurement; thus, higher resistivities can be measured. The samples can be sealed in ampoules and measured at high temperatures and pressures, limited only by the ampoule material. A typical calibration curve, made at 14 Mc and covering the range 10−6 Ω-cm to 108 Ω-cm is given; application to the estimation of sample homogeneity is discussed.
Towards trust-aware access management for ad-hoc collaborations (2007)

In an ad-hoc collaborative sharing environment, attribute-based access control provides a promising approach in defining authorization over shared resources based on userspsila properties/attributes rather than their identities. While the userpsilas attributes are always asserted by different authorities in the form of credentials, these authorities may not be accepted by the resource owner with the same degree of trust. In this paper, we present a trust-aware role-based authorization framework, called RAMARS_TM, to address both the access control and the trust management issues in such environment. Central to our approach is the dynamic role assignment based on a userpsilas attributes, and trust management, as a special constraint, is in place to make trust decisions on a userpsilas attributes. Required components and functions are identified and specified in our trust and access management policies. An architecture of prototype system implementation is also discussed.
HUMAN RENAL ISOGRAFTS: A CLINICAL AND PATHOLOGIC ANALYSIS1 (1968)

GLASSOCK, RICHARD J. M.D.2; FELDMAN, DONALD M.D.1; REYNOLDS, EDWARD S. M.D.3; DAMMIN, GUSTAVE J. M.D.1; MERRILL, JOHN P. M.D.4 Author Information
Digging into human rights violations: Data modelling and collective memory (2013)

Archives of human rights violations reports, by virtue of their poor metadata, basis in natural language, and scale, obscure fine grain analyses of violation event patterns. Cross-document coreference of victim or perpetrator occurrences from across a corpus is challenging, particularly when those mentions relate to different events. These challenges are emblematic of the transition from small scale to big data analysis in the humanities. This paper discusses these issues and proposes a framework to address these challenges so as to explore narrative construction and the formation of collective memory. Though our framework is based on processing human rights violation reports, it can be readily extended to support other big data problems in the humanities.
Biomarkers for Establishing a Tolerable Upper Intake Level for Vitamin C (1999)

Dietary reference intakes (DRIs) for vitamin C for healthy U.S. populations are currently being formulated by the Panel on Dietary Antioxidants and Related Compounds of the Food and Nutrition Board of the Institute of Medicine. A major task of the Panel is to analyze the evidence of adverse effects of high-dose vitamin C intakes to derive, if appropriate, a Tolerable Upper Intake Level (UL) for vitamin C. The present report details current and past research examining potential adverse effects of supplemental vitamin C. The available data indicate that very high intakes of vitamin C (2-4 g/day) are well tolerated biologically in healthy mammalian systems. Currently, strong scientific evidence to define and defend a UL for vitamin C is not available.
KeySlinger and StarSlinger: Secure Key Exchange and Encrypted File Transfer on Smartphones (2011)

Abstract : As the smartphone market continues to grow at a rapid pace, secure communication between these devices becomes an important issue. Smartphones are capable of being used in methods that differ vastly from the traditional desktop computing environment, making it possible to create new kinds of security protocols that take advantage of the mobility and other features provided by smartphones. This work presents KeySlinger and StarSlinger, apps for secure key exchange and authenticated/encrypted file transfer, respectively. KeySlinger is built on the SPATE protocol to exchange information between small (fewer than 8 people) or large groups of people in an authenticated manner. StarSlinger uses keys exchanged using KeySlinger to transfer authenticated and encrypted files between users.
Higher mRNA Levels of Chemokines and Cytokines Associated with Macrophage Activation in Erythema Migrans Skin Lesions in Patients from the United States than in Patients from Austria with Lyme Borreliosis (2007)

The EM lesions of B. burgdorferi-infected US patients expanded faster, were associated with more symptoms, and had higher mRNA levels of macrophage-associated chemokines and cytokines than did the EM lesions of B. afzelii-infected Austrian patients.
Early alteration of insulin stimulation of PI 3-kinase in muscle and adipocyte from gold thioglucose obese mice (1995)

The activation of phosphatidylinositol 3-kinase (PIK) was studied in vivo and in vitro in soleus muscle and adipocytes from young (8 wk) and old (30 wk) gold thioglucose obese mice. Insulin resistance assessed from muscle glucose transport and glycogen synthesis was present both in young and old obese mice. Adipocyte lipid synthesis and muscle glycolysis or glucose oxidation are not defective in young obese mice but become resistant later on. After incubation with 50 nM insulin, muscle antiphosphotyrosine-immunoprecipitable PIK activity was stimulated 5- to 10-fold in both young and old animals. This response was impaired by 56 and 75% in muscles from young and old obese mice, respectively. Insulin stimulation of receptor tyrosine kinase activity was only slightly decreased in muscle of young obese mice, whereas insulin receptor substrate 1 (IRS-1) tyrosine phosphorylation was blunted. The altered PIK stimulation in muscle, which is present both in vivo and in vitro, is thus characterized by a reduced association of PIK activity with IRS-1 and appears to result from a diminished IRS-1 tyrosine phosphorylation. In adipocytes isolated from lean mice, antiphosphotyrosine-immunoprecipitable PIK increased 25-fold within 10 min of incubation with insulin. This stimulation was markedly altered both in young and old obese mice, whereas lipogenesis was insulin resistant only in old obese animals. In adipocytes from young obese mice, insulin's stimulatory effect on the phosphorylation of insulin receptor beta-subunit, pp60, and an exogenous substrate was normal, whereas IRS-1 tyrosine phosphorylation was markedly depressed.(ABSTRACT TRUNCATED AT 250 WORDS)
Pen Pals (1985)

Charles W. Colson holds degrees from Brown University and George Washington University. He is president and founder of Prison Fellowship and author of Loving God, Born Again and Life Sentence.
Cellular expression of xanthine oxidoreductase protein in normal human tissues. (1999)

Xanthine oxidoreductase is an important cytoplasmic source of reactive oxygen species, and has been implicated in the pathogenesis of ischemia-reperfusion damage. Because the cellular localization of this protein remains unclear, our aim was to study its distribution in fresh normal human tissue obtained at surgery. For immunohistochemical studies we purified the protein from human milk and raised a polyclonal antibody in rabbits. In the liver the protein was preferentially localized to the periportal hepatocytes and it was absent from the perivenous region. In the proximal intestine, the protein was expressed in epithelial cells and goblet cells. Lactating mammary gland acinar cells showed intense staining. Small vessel vascular endothelial cells of the intestine, mammary gland, and skeletal muscle showed immunoreactivity, but in the kidney, glomerular endothelial cells were negative. No cells in the heart, brain, or lung expressed the enzyme protein. The observed localization of the xanthine oxidoreductase protein is consistent with previously observed enzyme activities in the organs studied. The widely assumed exclusive localization to capillary endothelium obviously does not apply to humans.
RASSF1A-Mediated Regulation of AREG via the Hippo Pathway in Hepatocellular Carcinoma (2013)

Ras association domain family 1 isoform A (RASSF1A) is a tumor suppressor that is methylated in many human cancers, including hepatocellular carcinoma (HCC). RASSF1A has been shown to suppress tumors via activation of the Hippo tumor suppressor pathway, including mammalian STE20-like kinase (MST). Amphiregulin (AREG), a target gene for Yes-associated protein (YAP), is a known oncogenic component of the Hippo pathway; however, the tumor-suppressive effect of RASSF1A on AREG in regard to regulation of the Hippo pathway remains unclear in HCC. Overexpression of RASSF1A in HCC cells, which lack functional RASSF1A, significantly inhibited cell proliferation and induced apoptosis by activating the Hippo pathway. Consequently, overexpression of RASSF1A inhibited the oncogenic functions of YAP, leading to a significant reduction in AREG secretion via regulation of the Hippo pathway. In human specimens, greater expression of RASSF1A was observed in chronic hepatitis/cirrhosis than in HCC, whereas expression of YAP and AREG was higher in 81% and 86% of HCC than in corresponding chronic hepatitis/cirrhosis, respectively. Furthermore, RASSF1A protein gradually decreased as multistep hepatocarcinogenesis progressed from chronic hepatitis/cirrhosis dysplastic nodules toward HCC, whereas the protein expression of YAP and AREG gradually increased. These findings provide mechanistic insight into the regulation of YAP and AREG by RASSF1A in human multistep hepatocarcinogenesis.
Optical interconnections for digital processing: a noncoherent method (1986)

We describe the use of a lenslet-array-based device for interconnections in optical digital computing systems. This new device, the digital lenslet array processor, operates in polychromatic and spatially incoherent light, so it can use a wide spectrum of electro-optical light sources. An experimental example is presented.
Immunoglobulin Excretion in Women with Recurrent Urinary Tract Infection (1973)

No AccessJournal of Urology1 Feb 1973Immunoglobulin Excretion in Women with Recurrent Urinary Tract Infection D.T. Uehling D.T. UehlingD.T. Uehling More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)60411-7AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Immunoglobulin Excretion in Women with Recurrent Urinary Tract Infection." The Journal of Urology, 109(2), pp. 302–303 © 1973 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byHilz M, Cohen M, Davis C and Warren M (2018) Acute and Chronic Bacterial Infection in the Rat Urinary Tract: Immunofluorescent Localization of ImmunoglobulinsJournal of Urology, VOL. 139, NO. 4, (840-843), Online publication date: 1-Apr-1988.Davis C, Cohen M, Anderson M, Reinarz J and Warren M (2018) Total and Specific Immunoglobulin Response to Acute and Chronic Urinary Tract Infections in a Rat ModelJournal of Urology, VOL. 138, NO. 5, (1308-1317), Online publication date: 1-Nov-1987. Volume 109Issue 2February 1973Page: 302-303 Advertisement Copyright & Permissions© 1973 by The American Urological Association Education and Research, Inc.MetricsAuthor Information D.T. Uehling More articles by this author Expand All Advertisement PDF downloadLoading ...
Improvement on OPC completeness through pre-OPC hot spot detection and fix (2008)

Design For Manufacturing (DFM) has been paid attention as the feature size on chip goes down below the k1 factor of 0.25. Lots of DFM related ideas have been come up, tried, and some of them adopted for wider process window and as a result, higher yield. As the minimum features are getting shrunk, the design rules become more complicated, but still not good enough to describe the complexity and limitation of certain patterns that imposes narrow process window, or even failure of device. Thus, it becomes essential to identify, correct, or remove the litho-unfriendly patterns (more widely called as hot spots), before OPC. One of the efforts is to write a DFM rules in addition to conventional DRC rules. In this study, we use the software, called YAM (Yield Analysis Module) to detect hot spots on pre-OPC layouts. Conventional DRC-based search is not able to surpass YAM, as it enables to identify hot spots in either much easier way or even ones that are unable to be found by DRC. We have developed a sophisticated methodology to detect and fix OPC- and/or litho-unfriendly patterns. It is confirmed to enlarge process window and the degree of freedom on OPC work.
Deactivation and Regeneration of Mo/ZSM-5 Catalysts for Methane Dehydroaromatization (2010)

The methane dehydroaromatization (DHA) was studied over a series of impregnated Mo/ZSM-5 catalysts with different molybdenum contents (1-10 wt.%). It was shown that total methane conversion was decreased by 30% during 12 h of DHA reaction. The benzene formation rate was increased from 0.5 to 13.9 mol C6H6/(gMo·s) when the molybdenum content in the catalyst was lowered from 10 to 1 wt.%. The deactivated Mo/ZSM-5 catalysts were studied by a group of methods: N2 adsorption, XRD, TGDTA, HRTEM and XPS. The content and condensation degree (C/H ratio) of the carbonaceous deposits was found to increase with an increase of either of the following parameters: molybdenum content (1-10 wt.%), reaction temperature (720-780 °C), space velocity (405-1620 h-1), reaction time (0.5-20 h). The stability of Mo/ZSM-5 catalysts in reaction-regeneration cycles was better when the time on stream was shorter. The regeneration conditions of deactivated Mo/ZSM-5 catalysts providing their stable operation under multiple reaction-regeneration cycles have been selected.
An analysis of the crossed twin delta loop antennas with circular polarization (1991)

Abstract In the circularly polarized antenna with two orthogonally placed wire antennas of identical shape, each antenna is fed with a phase difference of 90 degrees. In this paper, a crossed twin delta loop antenna is proposed in which two triangular delta loop antennas of different sizes are placed orthogonally. It is demonstrated in principle that this antenna can work as a circularly polarized antenna without any phase shifter. To make the phase difference of the currents between the orthogonal delta loops 90 degrees, the peripheral length of one of the triangular delta loop antennas is longer that that of another by the length corresponding to the phase delay of 90 degrees of the transmission line (=1/4 wavelength × 2). These orthogonally placed triangular delta loop antennas are fed in parallel with a single source. In this paper, a circularly polarized orthogonal equilateral triangular delta loop antenna with a reflector is considered. Detailed numerical studies are carried out for the axial ratio of the radiation field and the gain characteristics versus the spacing between the antenna and the reflector. As a result, an optimum shape is found in which the gain is high and the axial ratio of the circular polarization is good. For this structure, the input impedance, current distribution and radiation pattern are computed numerically so that the general characteristics of the present antenna are evaluated. The validity of the theory is confirmed by comparison with experiments.
Experimental Acute Cerebral Ischemia with Reperfusion (1996)

Experimental reperfused infarcts only 2 hours old demonstrate contrast enhancement with Gd-texaphyrin.
Reduced steady-state levels of rbcS mRNA in plants kept in the dark are due to differential degradation. (1991)

When plants are placed in the dark, the level of the abundant mRNA encoding the small subunit of ribulose-1,5-bisphosphate carboxylase (rbcS) declines rapidly. We present evidence demonstrating an active degradation of rbcS mRNA in the dark. Detailed analysis shows that transcripts originating from different members of the rbcS gene family are differentially affected by this degradation. This phenomenon is not common to all light-regulated plant genes since the mRNA for ST-LS1, another leaf-specific and light-induced gene, is not degraded in the dark within the same time scale.
Molecular Characterization of a Chromosomal Determinant Conferring Resistance to Zinc and Cobalt Ions in <i>Staphylococcus aureus</i> (1998)

A DNA fragment conferring resistance to zinc and cobalt ions was isolated from a genomic DNA library of Staphylococcus aureus RN450. The DNA sequence analysis revealed two consecutive open reading frames, designated zntR and zntA. The predicted ZntR and ZntA showed significant homology to members of ArsR and cation diffusion families, respectively. A mutant strain containing the null allele of zntA was more sensitive to zinc and cobalt ions than was the parent strain. The metal-sensitive phenotype of the mutant was complemented by a 2.9-kb DNA fragment containing zntR and zntA. An S. aureus strain harboring multiple copies of zntR and zntA showed an increased resistance to zinc. The resistance to zinc in the wild-type strain was inducible. Transcriptional analysis indicated that zntR and zntA genes were cotranscribed. The zinc uptake studies suggested that the zntA product was involved in the export of zinc ions out of cells.
CREB-binding Protein/p300 Activates MyoD by Acetylation (2000)

The myogenic protein MyoD requires two nuclear histone acetyltransferases, CREB-binding protein (CBP)/p300 and PCAF, to transactivate muscle promoters. MyoD is acetylated by PCAF in vitro, which seems to increase its affinity for DNA. We here show that MyoD is constitutively acetylated in muscle cells. In vitro, MyoD is acetylated both by CBP/p300 and by PCAF on two lysines located at the boundary of the DNA binding domain. MyoD acetylation by CBP/p300 (as well as by PCAF) increases its activity on a muscle-specific promoter, as assessed by microinjection experiments. MyoD mutants that cannot be acetylated in vitro are not activated in the functional assay. Our results provide direct evidence that MyoD acetylation functionally activates the protein and show that both PCAF and CBP/p300 are candidate enzymes for MyoD acetylation in vivo.
Effect of Sheet Surface Roughness on Clarity of Painted Sheet Steel (1989)

The influence of base metal surface roughness parameters on the clarity of painted automotive cold rolled sheet steels was investigated. The sheet steels were dull finished by shot blasting, electro-discharge texturing or laser dull texturing. It was found that the painted clarity improved with decreasing of Ra, while it scarcely depended on PPI. Characteristic of the surface profiles of base metal was the waviness with wavelength of hundreds micron. Whose trace remained after coating and deteriorated the clarity. In shot blasting, the dendritic microstructure and the statistical fluctuation of grit collision generated the waviness and made it difficult to control its wavelength. And, in electro-discharge texturing, it is suggested, controlling the waviness is difficult similarly. In laser dull texturing, it was possible to reduce the wavelength of waviness to less than hundreds micron and then to improve the clarity without deteriorating the press formability. A larger fraction of flat portion in laser dull texture was also responsible for the improvement of clarity.
When I am sixty five (2004)

A public sector pension has always been an attractive benefit for nurses. But, as reports, a review of the NHS scheme could change all that
Spiny lobsters: Fisheries and culture (2000)

Introduction . Fisheries (status reports) on Australia, New Zealand, Cuba, Caribbean, Africa, Pacific, Brazil, United States, Mexico . Management strategies . Aquaculture (larval rearing, juvenile grow--out, disease, nutrition, biological and economic potential) . Economics of fishing and handling . Economics of aquaculture . Marketing (United States, Japan, China, Europe) . Interaction between aquaculture and fisheries
Host targeted antiviral (HTA): functional inhibitor compounds of scaffold protein RACK1 inhibit herpes simplex virus proliferation (2019)

Due to the small number of molecular targets in viruses and the rapid evolution of viral genes, it is very challenging to develop specific antiviral drugs. Viruses require host factors to translate their transcripts, and targeting the host factor(s) offers a unique opportunity to develop broad antiviral drugs. It is well documented that some viruses utilize a host protein, Receptor for Activated C Kinase 1 (RACK1), to translate their mRNAs using a viral mRNA secondary structure known as the Internal Ribosomal Entry Site (IRES). RACK1 is essential for the translation of many viruses including hepatitis C (HCV), polio, Drosophila C (DCV), Dengue, Cricket Paralysis (CrpV), and vaccinia viruses. In addition, HIV-1 and Herpes Simplex virus (HSV-1) are known to use IRES as well. Therefore, host RACK1 protein is an attractive target for developing broad antiviral drugs. Depletion of the host's RACK1 will potentially inhibit virus replication. This background study has led us to the development of novel antiviral therapeutics, such as RACK1 inhibitors. By utilizing the crystal structure of the RACK1A protein from the model plant <i>Arabidopsis</i> and using a structure based drug design method, dozens of small compounds were identified that could potentially bind to the experimentally determined functional site of the RACK1A protein. The SPR assays showed that the small compounds bound strongly to recombinant RACK1A protein. Here we provide evidence that the drugs show high efficacy in inhibition of HSV-1 proliferation in a HEp-2 cell line. The drug showed similar efficacy as the available anti-herpes drug acyclovir and showed supralinear effect when applied in a combinatorial manner. As an increasing number of viruses are reported to use host RACK1 proteins, and more than 100 diverse animals and plant disease-causing viruses are known to use IRES-based translation, these drugs can be established as host-targeted broad antiviral drugs.