gebhart/patrepeval huggingface dataset:
Traffic Pattern-Based Adaptive Routing for Intra-Group Communication in Dragonfly Networks (2016)

The Cray Cascade architecture uses Dragonfly as its interconnect topology and employs a globally adaptive routing scheme called UGAL. UGAL directs traffic based on link loads but may make inappropriate adaptive routing decisions in various situations, which degrades its performance. In this work, we propose to improve UGAL by incorporating a traffic patternbased adaptation mechanism for intra-group communication in Dragonfly. The idea is to explicitly use the link usage statistics that are collected in performance counters to infer the traffic pattern, and to take the inferred traffic pattern plus link loads into consideration when making adaptive routing decisions. Our performance evaluation results on a diverse set of traffic conditions indicate that by incorporating the traffic pattern-based adaptation mechanism, our scheme is more effective in making adaptive routing decisions and achieves lower latency under low load and higher throughput under high load than the existing UGAL in many situations.
Security Analysis of RAPP An RFID Authentication Protocol based on Permutation. (2012)

One of the key problems in Radio Frequency Identification(RFID) is security and privacy. Many RFID authentication protocols have been proposed to preserve security and privacy of the system. Nevertheless, most of these protocols are analyzed and it is shown that they can not provide security against some RFID attacks. RAPP is a new ultralightweight authentication protocol with permutation. In RAPP, only three operations are involved: bitwise XOR, left rotation and permutation. In this paper, we give an active attack on RAPP. We first collect some authentication messages through impersonating valid tag and readers; Then we forge valid reader to communicate with the tag about times. Using the property of the left rotation and permutation operation, we can deduce the relationship of bits of random number or secret keys at different positions, thus obtain all the secret shared by the reader and the tag. 30 2
Joint position sense in total knee arthroplasty (1983)

Seventeen postoperative total knee arthroplasty (TKA) patients were evaluated using two tests of knee joint position sense. Young controls and age-matched controls underwent identical tests. The TKA patients also underwent gait analysis, including foot switch stride analysis, and clinical evaluation using a standard scoring system. Results showed statistically significant decreases in joint position sense from young controls to old controls, and further significant decreases with joint disease; however, no further worsening was noted as a result of TKA. The abnormal gait parameters seen in TKA patients correlated as well with position sense as with clinical score. Strongest correlations were seen when a combined clinical and proprioceptive score was compared with gait parameters. In spite of alleviation of pain and correction of deformity, normal gait and function are not typically achieved after total knee replacement. Irreversible loss of joint proprioceptive function due to the disease process may be a major factor in the discrepancy between clinical and functional outcomes of total joint arthroplasty. Furthermore, loss of proprioception and the resulting abnormal gait patterns may place increased stress on components and contribute to loosening. In addition, an association between degenerative joint disease and decline in proprioception is suggested.
Tooth detection and numbering in panoramic radiographs using convolutional neural networks (2019)

The performance of the proposed computer-aided diagnosis solution is comparable to the level of experts. Based on these findings, the method has the potential for practical application and further evaluation for automated dental radiograph analysis. Computer-aided teeth detection and numbering simplifies the process of filling out digital dental charts. Automation could help to save time and improve the completeness of electronic dental records.
Effect of Fertility Levels, Irrigation Schedules and Varieties on NPK Content and its Uptake in Linseed (Linum usitatissimum L.) (2012)

A field experiment was conducted at Agricultural Research Station Ummedganj, Kota. To find out the effect of fertility levels and irrigation schedules on Linseed varieties on vertisols of south-eastern Rajasthan during the year 2000–01 and 2001–02. on the basis of two years experimentation data show that either of the varieties did not give significant effect on N, P and K content in seed and straw of linseed. Irrigation at IW/CPR ratio of 0.7 gave significantly higher N and P content in seed and straw as compared of IW/CPE of 0.5 and 0.3. K content in seed and straw did not show significant effect with different irrigation schedules. 80kg N + 30kg P2O5 gave significantly higher in content in seed while 120kg N + 40kg P2O5 gave significantly higher P content in seed and straw. Effect of fertility levels on K content seed and straw was not found significant during both the year. Linseed variety recorded higher N, P and K uptake by seed and straw as compared to Rashmi. Irrigation at IW/CPE ratio of 0.5 gave higher N uptake by seed while in case of straw IW/CPE ratio 0.7 gave significant result. Irrigation at IW/CPE of 0.5 gave significant effect on P uptake by seed while irrigation at IW/CPE of 0.7 gave better result on P uptake by straw. Application of fertilizer at 80kg N + 30kg P2O5ha-1 gave significantly higher N & K uptake by seed while 120kg N + 40kg P2O5ha-1 gave significantly higher N uptake by straw. At fertility level 120kg N + 40kg P2O5ha-1 gave higher P uptake by seed and straw.
Is TGF-β a stemness regulator? (2009)

In this issue of Blood , Yamazaki and colleagues show that TGF-β inhibits cytokine-mediated LRC clustering in purified HSCs freshly isolated from the bone marrow and induces hibernation of HSCs ex vivo. Since cytokine stimulation of LRC is important to stimulate proliferation of HSCs, the authors
Vaccine repurposing approach for preventing COVID 19: can MMR vaccines reduce morbidity and mortality? (2020)

The coronavirus disease (COVID-19) is resulting in millions of infected individuals with several hundred thousands dead throughout the world. Amidst all the havoc, one interesting observation in the present COVID-19 pandemic is the negligible symptoms in the young; particularly children below 10 years of age. We assume the extensive pediatric vaccination with MMR vaccines followed globally could have resulted in innate immune responses, e.g., induction of interferons (IFNs) and activated natural killer (NK) cells, thereby offering natural immunity against SARS-CoV-2 in the young population. Possible cross-protective innate immunity offered by MMR vaccination prompted us to suggest repurposing MMR vaccination for immuno-prophylaxis against COVID-19.
Biological effects of PEMF (pulsing electromagnetic field): an attempt to modify cell resistance to anticancer agents. (1994)

Pulsing Electromagnetic Field (PEMF) effects lead to a modification of the multidrug resistance (MDR) of cells in vitro and in vivo. The murine leukemic doxorubicin-resistant cell line, P388/Dx, subjected to PEMF irradiation in vitro, showed a significant difference in thymidine incorporation when the concentration of doxorubicin reached a level of 1 microgram/mL, which corresponds to the inhibition dose 50 (ID50). The human lymphoblastic leukemia vinblastine-resistant cell line, CEM/VLB100, also showed a significant modification under the same experimental conditions at the in vitro ID50 corresponding to a vinblastine concentration of 100 ng/mL. BDF1 mice transplanted with P388/Dx cells also had an increase in their life span when doxorubicin was injected intraperitoneally in fractionated doses, while being subjected to PEMF irradiation.
An efficient transient audio coding algorithm based on DCT and Matching Pursuit (2010)

The paper proposes an efficient transient audio coding algorithm based on Discrete Cosine Transform (DCT) and sine extraction with Matching Pursuit (MP), which can be used conveniently in the sinusoidal parametric audio coder. The overlapped input frame is firstly classified into transient and non-transient signal. The transient detection is designed based on the energy ratio of the overlapped subframe to the whole frame. The transient signal can be represented with sinusoidal model in the DCT domain. After DCT processing, the sinusoids are extracted based on MP algorithm. The transient coding parameters contain a series of amplitudes, frequencies and phases in the DCT domain. Finally, a 15.5kbps wide-band transient audio coder is designed and the synthesized transient signal performs a little better than the one coded by MPEG-4 sinusoidal parametric coder.
Oncogenic signaling (1996)

Cancer develops when one or more cells begin to grow uncontrollably, presumably as a result of alterations in the highly regulated processes of normal cell division. These changes may result from germline or somatic mutations in genes that control normal cell proliferation, resulting in oncogenes. Oncogenes--originally defined as viral genes that transformed mammalian host cells--code for proteins with diverse functions. Antioncogenes, or tumor-suppressor genes, code for proteins acting as brakes in the cell cycle. Mutations in or deletions of these genes release the brakes. An overview of cellular signaling pathways, how they may be altered in cancers, and recently reported clinical implications of abnormal expression of some oncogenes and tumor-suppressor genes will be presented here.
Complementary fluorescence-polarization microscopy using division-of-focal-plane polarization imaging sensor (2012)

Fluorescence microscopy offers high sensitivity for disease diagnosis. However, little structural information is revealed by this method, requiring another technique to localize the source of fluorescence. We developed a complementary fluorescence-polarization microscope. We used a division-of-focal-plane charge coupled device polarization sensor to enable real-time video rate polarization imaging without any moving parts. The polarization information provided by the microscope enabled detection of structural element and complements the fluorescence information. Application of this multimodal system for cancer imaging using a tumor selective molecular probe revealed the association of diminished structural integrity of tumor tissue with high fluorescence of the imaging agent compared to surrounding normal tissue. This study demonstrates a new paradigm to improve cancer detection and diagnosis.
Genetic Engineering of Stimuli-Sensitive Silkelastin-like Protein Block Copolymers (2003)

Differentially charged analogues of block copolymers containing repeating sequences from silk (GAGAGS) and elastin (GVGVP) were synthesized using genetic engineering techniques by replacing a valine residue with glutamic acid. The sensitivity to pH and temperature was examined at various polymer concentrations, ionic strengths, and polymer lengths. The polymers transitioned from soluble to precipitate state over narrow temperature ranges. The transition temperature T(t) (the temperature at which half-maximal spectrophotometric absorption was observed) increased with increasing pH up to pH 7.0 and leveled off above this value for the Glu-containing polymer (17E)(11). T(t) was independent of pH for the Val-containing polymer (17V)(11). It decreased with increasing ionic strength, polymer concentration, and polymer length for both polymers. These results suggest that by substituting charged amino acids for neutral amino acids at strategic locations in the polymer backbone and by control of the length of silkelastin-like block copolymers using genetic engineering techniques, it is possible to precisely control sensitivity to pH, temperature, and ionic strength.
Procedure for the In Situ Calibration of Sonar Tranducers (1985)

Abstract : Sonar transducers are usually calibrated prior to installation on a ship. They are not, however, recalibrated after installation even though their receiving (and transmitting) properties can change significantly. In this report we present a procedure for the in situ calibration of sonar transducers at any desired time after installation when the ship is in open water. The procedure provides an up-to-date knowledge of the complex freefield sensitivity (or response) of each of the array transducers. This knowledge can be used to minimize, perhaps even eliminate, the adverse effects on array performance due to changes in the properties of one or more transducers. The in situ calibration procedure is based on a form of three-transducer reciprocity calibration that uses sound propagation factors to account for the influence of the ship's structure. The report describes how to obtain numerical values for the required sound propagation factors. It also describes how to use two-transducer comparison calibration to simplify the in situ calibration process, at least for highly reliable sonars. Keywords: In situ calibration; Transducer; Acoustic measurement; Reciprocity calibration; Sonar array.
HOP PRODUCTS (1986)

Hop products have established an important and permanent position in the brewing raw materials market. Hop pellets and hop extract offer significant advantages to traditional brewers. However, the ultimate hop product is the isomerised hop extract, which can now be produced without the involvement of organic solvents. Still to be resolved and hence controlled is the contribution of the hop oil fraction to beer flavour.
OPIATE MEDIATION OF AMENORRHOEA IN HYPERPROLACTINAEMIA AND IN WEIGHT‐LOSS RELATED AMENORRHOEA (1982)

Endogenous opiates are involved in the control of pituitary gonadotrophin and PRL secretion, and possibly of food intake. Both hyperprolactinaemia and weight loss (especially in anorexia nervosa) are frequently associated with amenorrhoea and an absence of gonadotrophin pulsatility. Since it has been suggested that increased endogenous opiate tone may operate in both conditions, we infused high-doses of naloxone into twelve patients with amenorrhoea of whom five had hyperprolactinaemia and seven had weight-loss related amenorrhoea. Eleven of the twelve patients had low levels of oestradiol (less than 50 pmol/l). Naloxone induced a marked rise in both LH and FSH levels in all of the five hyperprolactinaemic patients. In contrast, the patients with weight-loss amenorrhoea responded to naloxone with only a small or no rise in gonadotrophins. There was no consistent change in PRL in either group of patients. It is concluded that in hyperprolactinaemia, but not weight-loss amenorrhoea, there is an important endogenous opiate-mediated tonic inhibition of secretion of hypothalamic gonadotrophin releasing hormone.
A Temperature-Compensated Digitally-Controlled Crystal Pierce Oscillator for Wireless Applications (2008)

In this paper, the DCXO is based on a Pierce oscillator with two MIM capacitor arrays for tuning the anti-resonant frequency of a 19.2MHz crystal. Each array of MIM capacitors is thermometer-coded and formatted in a matrix shape to facilitate layout. Although a segmented architecture is an area-efficient method for implementing a SC array, a thermometer-coded array provides the best linearity and guarantees a monotonic frequency tuning characteristic, which is of utmost importance in an AFC system.
Preparation of Tourmaline Composite Materials and its Property of Far Infrared Radiance (2010)

The far infrared radiance tourmaline composite materials have been successfully prepared. From the XRD results, the composite materials were composed of tourmaline and transition metal oxides（Fe2O3, MnO2, Co2O3）and cerium oxide. Under SEM, the spherical particles of transition metal oxides were adsorbed by the flake particles of tourmaline. The composite materials show relatively high far infrared radiance than tourmaline and the mineral composite materials with smaller unit cell volume exhibits higher infrared radiance
Characterization of Staphylococcus pseudintermedius isolated from diseased dogs in Lithuania (2016)

The aim of this study was to characterize Staphylococcus pseudintermedius for its antimicrobial resistance and virulence factors with a special focus on methicillin-resistant (MRSP) strains isolated from sick dogs in Lithuania. Clinically sick adult dogs suffering from infections (n=214) and bitches with reproductive disorders (n=36) from kennels were selected for the study. Samples (n=192) from the 250 tested (76.8%) dogs were positive for Staphylococcus spp. Molecular profiling using the species-specific nuc gene identified 51 isolates as S. pseudintermedius (26.6% from a total number of isolated staphylococci) of which 15 isolates were identified as MRSP. Ten MRSP isolates were isolated from bitches with reproductive disorders from two large breeding kennels. Data on susceptibility of S. pseudintermedius to different antimicrobials revealed that all isolates were susceptible to vancomycin, daptomycin and linezolid. Two isolates (3.9%) were resistant to rifampicin. A high resistance was seen towards penicillin G (94.1%), tetracycline (64.7%) and macrolides (68.7%). Resistance to fluoroquinolones ranged from 25.5% (gatifloxacin) to 31.4% (ciprofloxacin). The most prevalent genes encoding resistance included blaZ, aac(6')-Ie-aph(2'')-Ia, mecA, and tet(M). The Luk-I gene encoding a leukotoxin was detected in 29% of the isolates, whereas the siet gene encoding exfoliative toxin was detected in 69% of the S. pseudintermedius isolates. This report of MRSP in companion animals represents a major challenge for veterinarians in terms of antibiotic therapy and is a concern for both animal and public health.
Characterization of long RNA-cleaving deoxyribozymes with short catalytic cores: the effect of excess sequence elements on the outcome of in vitro selection (2006)

We previously conducted an in vitro selection experiment for RNA-cleaving deoxyribozymes, using a combinatorial DNA library containing 80 random nucleotides. Ultimately, 110 different sequence classes were isolated, but the vast majority contained a short14-15 nt catalytic DNA motif commonly known as 8-17. Herein, we report extensive truncation experiments conducted on multiple sequence classes to confirm the suspected catalytic role played by 8-17 and to determine the effect of excess sequence elements on the activity of this motif and the outcome of selection. Although we observed beneficial, detrimental and neutral consequences for activity, the magnitude of the effect rarely exceeded 2-fold. These deoxyribozymes appear to have survived increasing selection pressure despite the presence of additional sequence elements, rather than because of them. A new deoxyribozyme with comparable activity, called G15-30, was approximately 2.5-fold larger and experienced a approximately 4-fold greater inhibitory effect from excess sequence elements than the average 8-17 motif. Our results suggest that 8-17 may be less susceptible to the potential inhibitory effects of excess arbitrary sequence than larger motifs, which represents a previously unappreciated selective advantage that may contribute to its widespread recurrence.
Kindred domains (2014)

In this paper we focus on detecting and clustering distinct groupings of domain names that are queried by numerous sets of infected machines. We propose to analyze domain name system (DNS) traffic, such as Non-Existent Domain (NXDomain) queries, at several premier Top Level Domain (TLD) authoritative name servers to identify strongly connected cliques of malware related domains. We illustrate typical malware DNS lookup patterns when observed on a global scale and utilize this insight to engineer a system capable of detecting and accurately clustering malware domains to a particular variant or malware family without the need for obtaining a malware sample. Finally, the experimental results of our system will provide a unique perspective on the current state of globally distributed malware, particularly the ones that use DNS.
Coxsackievirus B transmission and possible new roles for extracellular vesicles (2013)

Coxsackievirus B1, a member of the Picornaviridae family is a non-enveloped single-stranded RNA virus associated with human diseases including myocarditis and pancreatitis. Infection of the intestinal mucosa, lined by polarized epithelial cells, requires interaction of coxsackievirus with apically located DAF (decay-accelerating factor) before transport to the basolaterally located CAR (coxsackie and adenovirus receptor), where entry is mediated by endocytosis. As with many other non-enveloped viruses, coxsackievirus has to induce lysis of host cells in order to perpetuate infection. However, recent evidence indicates that virus spread to secondary sites is not only achieved by a lytic mechanism and a non-lytic cell-cell strategy has been suggested for coxsackievirus B3. A physical interaction between infected and non-infected cells has been shown to be an efficient mechanism for retroviral transmission and one type of extracellular vesicle, the exosome, has been implicated in HIV-1 transmission. HIV-1 also takes advantage of depolymerization of actin for spread between T-cells. Calpain-mediated depolymerization of the actin cytoskeleton, as a result of increases in intracellular calcium concentration during coxsackievirus infection, would result in a release of host cell-derived microvesicles. If so, we speculate that maybe such microvesicles, increasingly recognized as major vehicles mediating intercellular communication, could play a role in the intercellular transmission of non-enveloped viruses.
Separation of enzymes from microorganism crude extracts by free‐flow zone electrophoresis (1996)

Continuous, single-step, state-of-the-art preparative separations of enzymes from microorganism crude extracts by free-flow zone electrophoresis are presented. In the first example, the enzymes formate dehydrogenase, formaldehyde dehydrogenase, and methanol oxidase were continuously separated from Candida boidinii crude extract. Yields of 85% to 95% and purification factors between 3 and 7 were obtained along with a simultaneous separation of the finer cell debris from the enzymes. Using multiple injections of sample, a throughput of 46.2 mg protein/h was recorded. In the second example, a fivefold purification of β-galactosidase from Escherichia coli was achieved along with complete, simultaneous cell debris separation from the enzyme. The yield of the enzyme was greater than 90%. The preparative free-flow zone electrophoresis experiments were run continuously for a period of 12 h and the separations were found to be stable; i.e., the enzymes and the cell debris eluted at their respective fraction numbers during the entire period. In both examples, choice of the type of buffer played a critical role and had to be investigated and optimized experimentally. Scale-up aspects of the separations are also discussed. Recently, by comparison of free-flow zone electrophoresis with ion-exchange chromatography, we have presented evidence that free-flow electrophoresis separations are governed by net surface charge (S. Nath et al., Biotechnol. Bioeng. 1993, 42: 829–835). Here, we offer further confirmation of this evidence by comparison of preparative free-flow zone electrophoresis experiments at various pHs on a mixture of two model proteins with analytical electrophoretic titration curves of the proteins. We are thus in a position to predict separations in free-flow zone electrophoresis. © 1996 John Wiley & Sons, Inc.
Conditional and Structural Error Correction Models (1994)

A "structural" error correction model (in Boswijk's sense) is a representation of a conditional error correction model that satisfies certain restrictions. This paper examines the conditions under which such a structural error correction model exists and when the associated representation is of interest. To clarify the nature of such models, several analytical and empirical examples are considered, which violate those conditions. Structural error correction models are economically appealing, but their limitations imply that some care must be taken when applying them in practice.