gebhart/patrepeval huggingface dataset:
Stroke or Transient Ischemic Attack in Patients With Transvenous Pacemaker or Defibrillator and Echocardiographically Detected Patent Foramen Ovale (2013)

In patients with endocardial leads, the presence of a PFO on routine echocardiography is associated with a substantially increased risk of embolic stroke/TIA. This finding suggests a role of screening for PFOs in patients who require cardiac implantable electronic devices; if a PFO is detected, PFO closure, anticoagulation, or nonvascular lead placement may be considered.
Effect of Fluoroquinolone Concentration on Selection of Resistant Mutants of <i>Mycobacterium bovis</i> BCG and <i>Staphylococcus aureus</i> (1999)

When Mycobacterium bovis BCG and Staphylococcus aureus were plated on agar containing increasing concentrations of fluoroquinolone, colony numbers exhibited a sharp drop, followed by a plateau and a second sharp drop. The plateau region correlated with the presence of first-step resistant mutants. Mutants were not recovered at concentrations above those required for the second sharp drop, thereby defining a mutant prevention concentration (MPC). A C-8-methoxy group lowered the MPC for an N-1-cyclopropyl fluoroquinolone.
Plasma-enhanced metalorganic chemical vapor deposition of BaTiO3 films (1992)

BaTiO3 films have been grown by plasma-enhanced metalorganic chemical vapor deposition (PE-MOCVD) for the first time. The BaTiO3 films were grown on Pt-coated Si substrates in an inverted vertical reactor with a remote O2 plasma at 450 mTorr. Plasma powers exceeding 10 W reduced or eliminated the presence of CO3 in the as-grown films at 525 and 600 °C, respectively. Films deposited at 600 °C by PE-MOCVD were polycrystalline BaTiO3 with perovskite structure and partial texture in the [100] direction; films grown at 525 °C were amorphous. The polycrystalline BaTiO3 films had dielectric constants as large as 300, loss tangents of 0.02, and resistivities exceeding 109 Ω cm at room temperature.
Abilities of peroxidases to catalyse peroxidase-oxidase oxidation of thiols (1988)

The abilities of various peroxidases to catalyse the peroxidase-oxidase oxidation of seven aminothiols were studied. Cysteamine and cysteine esters were found to be peroxidase-oxidase substrates for eosinophil peroxidase and myeloperoxidase, whereas other thiols tested were inactive or poorly active with these peroxidases. With lactoperoxidase and horseradish peroxidase, all the tested thiols were inactive or poorly active as peroxidase-oxidase substrates. These studies suggest that a main reason for thiols being poor peroxidase-oxidase substrates is because these thiols are poor peroxidatic substrates.
Corneal Imaging Revisited: An Overview of Corneal Reflection Analysis and Applications (2013)

The cornea of the human eye acts as a mirror that reflects light from a person's environment. These corneal reflections can be extracted from an image of the eye by modeling the eye-camera geometry as a catadioptric imaging system. As a result, one obtains the visual information of the environment and the relation to the observer (view, gaze), which allows for application in a number of fields. The recovered illumination map can be further applied to various computational tasks. This paper provides a comprehensive introduction on corneal imaging, and aims to show the potential of the topic and encourage advancement. It makes a number of contributions, including (1) a combined view on previously unrelated fields, (2) an overview of recent developments, (3) a detailed explanation on anatomic structures, geometric eye and corneal reflection modeling including multiple eye images, (4) a summary of our work and contributions to the field, and (5) a discussion of implications and promising future directions. The idea behind this paper is a geometric framework to solve persisting technical problems and enable non-intrusive interfaces and smart sensors for traditional, ubiquitous and ambient environments.
Handbook of algorithms and data structures : in Pascal and C (1991)

Table of Contents Introduction Basic Concepts Searching Algorithms Sorting Algorithms Selection Algorithms Arithmetic Algorithms Text Algorithms Appendixes
Method and spectrometer for measuring optical absorption in thin epitaxial layers (1976)

A non destructive method and an apparatus are described which can be used to measure the optical absorption coefficient in thin semiconductor layers. By using a long optical path length, absorption coefficients of the order of 0.05 cm-1 can be measured.
Two different one-dimensional structural motifs in the same coordination polymer: a novel interpenetration of infinite ladders by bundles of infinite chains (2001)

A coordination polymer with a novel structural motif consisting of stacks of infinite ladders interpenetrated by bundles of infinite chains is described; geometrical arguments are made for the requirements that can lead to such interpenetration as a function of ligand dimensions.
Spatial-Frequency Encoding Techniques Applied to a One-Tube Color Television Camera (1970)

An analysis and experimental results are presented of a new color camera technique using a single camera tube. To avoid the difficult registration problem of conventional color cameras, the color information is encoded as the amplitude of two diffraction grating patterns. This is accomplished by imaging the colored scene onto a pair of colored diffraction gratings. The recovery of the color information is done by bandpass filtering of each channel followed by envelope detection. The three color signals are derived using linear combinations of the two decoded carriers along with the average signal, which represents a weighted sum of all three colors.
Pulsed, single-frequency, ring laser with a holographic output coupler (2011)

A unidirectional, passively Q-switched, 2.05-μm Ho:YLF ring laser providing single-frequency, sub-mJ-energy, 100-200-ns-long laser pulses at a kHz rate is reported. The wavelength selection and "coarse" spectral narrowing is performed by utilizing a volume Bragg grating as a resonant, narrowband output coupler operated at a small angle away from normal incidence. Pulsed operation of the Ho:YLF oscillator and further spectral narrowing down to a single longitudinal mode is achieved via passive Q-switching using a Cr2+-doped saturable absorber.
Marinobacter lipolyticus sp. nov., a novel moderate halophile with lipolytic activity (2003)

In the course of a screening programme in hypersaline habitats of southern Spain to isolate halophilic bacteria that are able to produce different extracellular enzymes, a novel, moderately halophilic bacterium (strain SM19(T)) that displays lipolytic activity has been isolated and characterized. Strain SM19(T) is a Gram-negative rod that grows optimally in culture media that contain 7.5 % NaCl. The DNA G+C content was 57.0 mol%. According to phenotypic and genotypic data, this strain was assigned to the genus MARINOBACTER: However, 16S rDNA sequence similarity between strain SM19(T) and species of the genus Marinobacter was <96.7 %; this value is sufficiently low to propose its designation as a novel species. In addition, DNA-DNA hybridization with reference strains of close phylogenetic relatives was between 11 and 19 %. On the basis of these data, the inclusion of strain SM19(T) in the genus Marinobacter as a novel species is proposed, with the name Marinobacter lipolyticus sp. nov. The type strain of the novel species is SM19(T) (=DSM 15157(T)=NCIMB 13907(T)=CIP 107627(T)=CCM 7048(T)).
V-<i>src</i>-induced-transcription of the avian clusterin gene (1992)

We have isolated the avian gene T64 corresponding to the mammalian clusterin, on the basis of high accumulation of its template mRNA in cells infected with oncogenic retroviruses. Since the clusterin was shown to have a protective effect against the immune system, its induction by oncogenic viruses is of major biological importance. The unique, short 5 kb-long T64 genomic locus is inactive in normal quail embryo fibroblasts in primary culture whereas it shows a high transcriptional activity after transformation by the Rous sarcoma virus. The 963 bp-long 5' flanking region is sufficient to drive the transcription of the chloramphenicol acetyltransferase reporter gene in a thermodependent manner when a thermosensitive version of pp60v-src is used. Deletion and point mutation analyses of the promoter show that the v-src response requires at least two separate elements: PUR and AP-1, located respectively at positions -167 to -152 and -25 to -19 relative to the single transcription initiation site. In addition, the binding of specific nuclear factors to these responsive elements correlates with the T64 promoter activation.
Ossiculoplasty by interposition of a minor columella between the tympanic membrane and stapes head. (1996)

This study analyzes short- and long-term results of 436 ossiculoplasties accomplished by a minor columella sculptured in the remnants of the incus and placed between the tympanic membrane and stapes head. Most cases were operated on by a transcanal approach through an ear speculum, under local anesthesia. Cases in which an associated mastoidectomy was performed to remove diseased tissue are excluded. The residual air-bone gap was < 20 dB in 86.1% of cases 2 months after surgery, in 77.0% 1 year later, and then remained stable over time, even in patients seen 5 to 15 years after the operation. Complications were rare. A total sensorineural hearing loss occurred in two cases (0.4%), the cause of which remained unexplained. Other complications included a high-frequency hearing loss in 10 (2.3%) cases, tinnitus in 12 (2.7%), and transitory vertigo in two (0.4%). We conclude that this type of ossiculoplasty is a simple but adequate procedure for primary restoration of hearing in chronic otitis media if the stapes is intact and mobile.
Biomarkers of Endothelial Cell Activation Serve as Potential Surrogate Markers for Drug-induced Vascular Injury (2010)

Drug-induced vascular injury (DIVI) is a nonclinical finding that often confounds the toxicological evaluation of investigational drugs, but there is an absence of qualified biomarkers that can be used to detect and monitor its appearance in animals and patients during drug development and clinical use. It is well known that endothelial cell (EC) activation plays a key role in the expression and evolution of DIVI, and the various immunological and inflammatory factors involved in its expression may serve as potential biomarker candidates. Activated ECs change their morphology and gene expression, generating endothelial adhesion molecules, pro-coagulant molecules, cytokines, chemokines, vasodilators, nitric oxide, and acute-phase reactants. This review provides a brief historical background of EC activation and the search for biomarkers of early EC activation for monitoring DIVI. At present, no biomarkers of EC activation have been qualified to predict DIVI in the nonclinical or clinical context, and a robust pathologic foundation for their use is still lacking. We propose three categories of EC activation biomarkers: recommended surrogate markers, potentially useful markers, and emerging candidate markers. This review alerts pharmaceutical companies, research institutions, and regulatory agencies to the continuing need for reliable biomarkers of EC activation in drug development.
Influence of near‐surface volcanic structure on long‐period seismic signals and on moment tensor inversions: Simulated examples from Mount Etna (2008)

Long‐period (LP) seismicity on volcanoes is thought to be associated with moving fluids or resonating fluid‐filled conduits, hence LP moment tensor (MT) source inversions might have a direct bearing on our understanding of the plumbing system. Using 3‐D full wavefield simulations and 2‐D sensitivity kernels in a digital elevation model of Mount Etna, we investigate the influence of near‐surface volcanic structure on LP signals and on moment tensor inversions. Contrary to common wisdom in crustal seismology we find that, despite their relatively long wavelengths, LPs are severely distorted by near‐surface structures including layering and topographic features. In particular near‐surface low‐velocity structures which are commonly observed on volcanoes play a critical role in controlling the nature of LP signals. If not accounted for, these path effects leak into the source solution, leading to the emergence of erroneous source geometries, spurious forces and incorrect source time functions. This is particularly problematic if one adopts an “unconstrained” solution space for the source, with many free parameters. Hence there is a fine balance in the trade‐off between the velocity model and the source. In the absence of high‐resolution near‐surface velocity control we demonstrate the importance of employing a priori source information from other fields (e.g., structural geology), for shallow LPs, constraining the number of free parameters in the inversion. A probabilistic approach should then be taken, as the model with the “best fit” is not necessarily the “true” solution.
Evaluation of the Effect of Temperature on a Stem Elongation Model of Phalaenopsis (2019)

Phalaenopsis orchid has become one of the most important potted plants in flower markets. However, the timing at which flowers reach the saleable stage can be very important since the demand may be larger for specific holidays. The regulation of stem growth could serve as an opportunity for regulation of flowering. The purpose of this study was to evaluate the effect of temperature on stem elongation. In this study, a stem elongation model established by a statistical technique was used to evaluate the effect of temperature. The stem lengths of four named Phalaenopsi varieties and 15 unnamed Phalaenopsi hybrids were measured under different temperature regimes. The three parameters of the logistic growth model, the maximum stem length, growth rate, and inflection point at which the growth rate reached a maximum value were estimated by using nonlinear regression analysis. Then, the differences among varieties in these three parameters were assessed by categorical testing. The results of this study indicated that stem growth rate was positively affected only by day temperature. The maximum stem length was negatively affected by the day temperature and positively influenced by the temperature difference between day and night. The results of this study could provide a practical method to regulate stem elongation by adjusting the temperatures, thus helping growers time the flowering of their potted orchids to meet market demand.
Digestive proteinases of the larger black flour beetle, <i>Cynaeus angustus</i> (Coleoptera: Tenebrionidae) (2006)

Digestion in the larger black flour beetle, Cynaeus angustus (LeConte), was studied to identify new control methods for this pest of stored grains and grain products. The physiological pH of the larval gut, as measured with extracts in water, was approximately 6.1, and the pH for optimal hydrolysis of casein by gut extracts was 6.2 when buffers were reducing. However, under non-reducing conditions, hydrolysis of casein and synthetic serine proteinase substrates was optimal in alkaline buffer. Three major proteinase activities were observed in zymograms using casein or gelatin. Caseinolytic activity of C. angustus gut extracts was inhibited by inhibitors that target aspartic and serine proteinase classes, with minor inhibition by a cysteine proteinase inhibitor. In particular, soybean trypsin and trypsin/chymotrypsin inhibitors were most effective in reducing the in vitro caseinolytic activity of gut extracts. Based on these data, further studies are suggested on the effects of dietary soybean inhibitors of serine proteinases, singly and in combination with aspartic and cysteine proteinase inhibitors, on C. angustus larvae. Results from these studies can be used to develop new control strategies to prevent damage to grains and stored products by C. angustus and similar coleopteran pests.
Converting the Cross (2020)

This chapter examines the post-Reformation afterlives of churchyard, wayside and market crosses. It explores how they were implicated in the Protestant war against idols alongside the manner in which many were recycled for alternative purposes, probing the new layers of meaning they acquired as they were modified and the contested legacies they left to the generations that inherited them. Particular attention is paid to crosses upon whose decapitated pedestals subsequently became the base for sundials. It argues that crosses converted into timekeepers not merely illuminate the interconnections between memory and materiality, space and temporality, in post-Reformation culture. They also offer insight into the evolving concept of the ‘monument’ itself. They afford a glimpse of the process by which things designed to provoke remembrance became things worthy of preservation as historic artefacts themselves. They became signposts to a disappearing past that had to be fossilised lest it be lost.
High Power Density from a Miniature Microbial Fuel Cell Using <i>Shewanella oneidensis</i> DSP10 (2006)

A miniature microbial fuel cell (mini-MFC) is described that demonstrates high output power per device cross-section (2.0 cm2) and volume (1.2 cm3). Shewanella oneidensis DSP10 in growth medium with lactate and buffered ferricyanide solutions were used as the anolyte and catholyte, respectively. Maximum power densities of 24 and 10 mW/m2 were measured using the true surface areas of reticulated vitreous carbon (RVC) and graphite felt (GF) electrodes without the addition of exogenous mediators in the anolyte. Current densities at maximum power were measured as 44 and 20 mA/m2 for RVC and GF, while short circuit current densities reached 32 mA/m2 for GF anodes and 100 mA/m2 for RVC. When the power density for GF was calculated using the cross sectional area of the device or the volume of the anode chamber, we found values (3 W/m2, 500 W/m3) similar to the maxima reported in the literature. The addition of electron mediators resulted in current and power increases of 30-100%. These power densities were surprisingly high considering a pure S. oneidensis culture was used. We found that the short diffusion lengths and high surface-area-to-chamber volume ratio utilized in the mini-MFC enhanced power density when compared to output from similar macroscopic MFCs.
The <i>Candida albicans pescadillo</i> homolog is required for normal hypha-to-yeast morphogenesis and yeast proliferation (2008)

A single species, Candida albicans, causes half of all invasive fungal infections in humans. Unlike other fungal pathogens, this organism switches between growth as budding yeast and as pseudohyphal and hyphal filaments in host organs and in vitro. Both cell types play a role in invasive disease: while hyphal and pseudohyphal filaments penetrate host cells and tissues, yeast cells are likely to facilitate dissemination through the bloodstream and establishment of distant foci of infection. Many regulators of the yeast-to-hypha switch have emerged from intensive investigations of this morphogenetic step, but the hypha-to-yeast switch remains poorly understood. Using a forward genetic approach, a novel putative regulator involved in the hypha-to-yeast switch was identified, the C. albicans pescadillo homolog, PES1. In eukaryotes from yeast to human, pescadillo homologs are involved in cell cycle control and ribosome biogenesis, and are essential. We find a pescadillo homolog to act in fungal morphogenesis, specifically in lateral yeast growth on filamentous cells. We also find essentiality of PES1 in C. albicans to be dependent on cell type, because hyphal cells, but not yeast cells, tolerate its loss. PES1 is therefore critical for completion of the C. albicans life cycle, in which the fungus switches between filamentous and yeast growth. Consistent with these in vitro findings, PES1 is required for C. albicans virulence in an in vivo insect model of infection.
Inductively coupled plasma mass spectrometry with direct injection nebulization for mercury analysis of drinking water (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInductively coupled plasma mass spectrometry with direct injection nebulization for mercury analysis of drinking waterM. J. Powell, E. S. K. Quan, D. W. Boomer, and Daniel R. WiederinCite this: Anal. Chem. 1992, 64, 19, 2253–2257Publication Date (Print):October 1, 1992Publication History Published online1 May 2002Published inissue 1 October 1992https://pubs.acs.org/doi/10.1021/ac00043a012https://doi.org/10.1021/ac00043a012research-articleACS PublicationsRequest reuse permissionsArticle Views324Altmetric-Citations63LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Fluorescence Resonance Energy Transfer in Quantum Dot-Protein Kinase Assemblies (2007)

In search of viable strategies to identify selective inhibitors of protein kinases, we have designed a binding assay to probe the interactions of human phosphoinositide-dependent protein kinase-1 (PDK1) with potential ligands. Our protocol is based on fluorescence resonance energy transfer (FRET) between semiconductor quantum dots (QDs) and organic dyes. Specifically, we have expressed and purified the catalytic kinase domain of PDK1 with an N-terminal histidine tag [His(6)-PDK1(DeltaPH)]. We have conjugated this construct to CdSe-ZnS core-shell QDs coated with dihydrolipoic acid (DHLA) and tested the response of the resulting assembly to a molecular dyad incorporating an ATP ligand and a BODIPY chromophore. The supramolecular association of the BODIPY-ATP dyad with the His(6)-PDK1(DeltaPH)-QD assembly encourages the transfer of energy from the QDs to the BODIPY dyes upon excitation. The addition of ATP results in the displacement of BODIPY-ATP from the binding domain of the His(6)-PDK1(DeltaPH) conjugated to the nanoparticles. The competitive binding, however, does not prevent the energy transfer process. A control experiment with QDs, lacking the His(6)-PDK1(DeltaPH), indicates that the BODIPY-ATP dyad adsorbs nonspecifically on the surface of the nanoparticles, promoting the transfer of energy from the CdSe core to the adsorbed BODIPY dyes. Thus, the implementation of FRET-based assays to probe the binding domain of PDK1 with luminescent QDs requires the identification of energy acceptors unable to interact nonspecifically with the surface of the nanoparticles.