gebhart/patrepeval huggingface dataset:
Motor Skill Development of Children with HIV Infection Measured with the Peabody Developmental Motor Scales (2002)

Clinicians working with children who are HIV+ should emphasize intervention strategies generally designed to develop all gross motor skills and the specific fine motor skills of "eye-hand coordination" and "manual dexterity."
A maximum-likelihood surface estimator for dense range data (2002)

Describes how to estimate 3D surface models from dense sets of noisy range data taken from different points of view, i.e., multiple range maps. The proposed method uses a sensor model to develop an expression for the likelihood of a 3D surface, conditional on a set of noisy range measurements. Optimizing this likelihood with respect to the model parameters provides an unbiased and efficient estimator. The proposed numerical algorithms make this estimation computationally practical for a wide variety of circumstances. The results from this method compare favorably with state-of-the-art approaches that rely on the closest-point or perpendicular distance metric, a convenient heuristic that produces biased solutions and fails completely when surfaces are not sufficiently smooth, as in the case of complex scenes or noisy range measurements. Empirical results on both simulated and real ladar data demonstrate the effectiveness of the proposed method for several different types of problems. Furthermore, the proposed method offers a general framework that can accommodate extensions to include surface priors, more sophisticated noise models, and other sensing modalities, such as sonar or synthetic aperture radar.
Radiation Decomposition of Pure Organic Compounds (1955)

The fact that ionizing radiation can cause changes in organic has been known for many years, but it has only been in the last twenty to thirty years that much work has been done on determining the specific changes in organic produced by nuclear radiation, or equivalent artificially produced radiation. Indeed, real progress has been made in this field only in the last ten years or so. This review2 will attempt to cover only radiation changes of a chemical nature in organic produced by ionizing radiation. Changes is perhaps a better word than decomposition, since we wish to deal with a variety of effects observed from irradiation-among which effects are fusion (including dimerization and polymerization),3 molecular fission into many different size fragments, oxidation, reduction, rearrangement, and exchanges. By the term pure organic compounds we mean to exclude all solution work and mixtures of organic compounds. Since about half of the papers (1, 2) dealing with radiation effects that have appeared in recent years have concerned aqueous solutions, and of the remaining only a few are purely organic chemical studies, we are dealing with a rather specialized subject. Our subject is, however, fundamental to the effect of radiation on organic in aqueous solution, as it is a partial isolation of one of the contributors to the over-all changes observed in the irradiation of solutions.
SPECT image analysis using statistical parametric mapping in patients with Parkinson's disease. (1999)

SPM analysis showed that significant rCBF changes in Parkinson's disease accompanied disease progression and related to disease pathophysiology in the functional architecture of thalamocortex-basal ganglia circuits and related systems.
Type-A Arabidopsis Response Regulators Are Partially Redundant Negative Regulators of Cytokinin Signaling[W] (2004)

Type-A Arabidopsis (Arabidopsis thaliana) response regulators (ARRs) are a family of 10 genes that are rapidly induced by cytokinin and are highly similar to bacterial two-component response regulators. We have isolated T-DNA insertions in six of the type-A ARRs and constructed multiple insertional mutants, including the arr3,4,5,6,8,9 hextuple mutant. Single arr mutants were indistinguishable from the wild type in various cytokinin assays; double and higher order arr mutants showed progressively increasing sensitivity to cytokinin, indicating functional overlap among type-A ARRs and that these genes act as negative regulators of cytokinin responses. The induction of cytokinin primary response genes was amplified in arr mutants, indicating that the primary response to cytokinin is affected. Spatial patterns of ARR gene expression were consistent with partially redundant function of these genes in cytokinin signaling. The arr mutants show altered red light sensitivity, suggesting a general involvement of type-A ARRs in light signal transduction. Further, morphological phenotypes of some arr mutants suggest complex regulatory interactions and gene-specific functions among family members.
Nucleation of Solid in an Undercooled Liquid by Cavitation (1966)

Cavitation in an undercooled liquid can nucleate solid. We have demonstrated, by a new experimental technique, that nucleation occurs when a cavity collapses, rather than when it expands. Extremely large pressures, ∼105 atm, are generated by the collapse of a cavity. The change in pressure lowers the freezing temperature of the liquid, and thereby results in nucleation. It is suggested that nucleation by scratching also takes place through the medium of cavitation.
Advantages of Radial Basis Function Networks for Dynamic System Design (2011)

Radial basis function (RBF) networks have advantages of easy design, good generalization, strong tolerance to input noise, and online learning ability. The properties of RBF networks make it very suitable to design flexible control systems. This paper presents a review on different approaches of designing and training RBF networks. The recently developed algorithm is introduced for designing compact RBF networks and performing efficient training process. At last, several problems are applied to test the main properties of RBF networks, including their generalization ability, tolerance to input noise, and online learning ability. RBF networks are also compared with traditional neural networks and fuzzy inference systems.
<i>Neisseria meningitidis</i>B vaccines: recent advances and possible immunization policies (2014)

Since the development of the first-generation vaccines based on outer membrane vesicles (OMV), which were able to contain strain-specific epidemics, but were not suitable for universal use, enormous steps forward in the prevention of Neisseria meningitidis B have been made. The first multicomponent vaccine, Bexsero(®), has recently been authorized for use; other vaccines, bivalent rLP2086 and next-generation OMV vaccines, are under development. The new vaccines may substantially contribute to reducing invasive bacterial infections as they could cover most Neisseria meningitidis B strains. Moreover, other potentially effective serogroup B vaccine candidates are being studied in preclinical settings. It is therefore appropriate to review what has recently been achieved in the prevention of disease caused by serogroup B.
Presentation of abundant endogenous class II DR‐restricted antigens by DM‐negative B cell lines (1997)

Peptides derived from endogenous and exogenous antigens compete for binding and presentation via class II molecules. Studies with mutant B cell lines defective in exogenous antigen presentation suggest that HLA-DM molecules facilitate the interaction of foreign peptides and class II molecules. In contrast, presentation of self antigens is not strictly dependent upon HLA-DM, as demonstrated by the ability of these mutant cells to activate T cells specific for endogenous antigens. Two distinct classes of DM-negative cells, T2 cells generated by in vitro mutagenesis and lines derived from bare lymphocyte syndrome (BLS) patients, were able to present epitopes derived from self proteins. Transfection of DM genes into the mutant cells enhanced the presentation of some, but not all, endogenous antigens, suggesting that formation of select endogenous peptide/class II complexes is not dependent upon DM. The efficiency of endogenous antigen presentation in the absence of DM was also dependent on the mutant antigen-presenting cell studied, as the TxB hybrid T2 presented greater amounts of self peptides compared to cells from BLS patients. Thus, additional genes, aside from DM, may regulate the pathway for endogenous antigen presentation.
An interactive system for page layout design (1974)

A prototype interactive page layout system is described in which textual and pictorial information can be manipulated under computer control on a scanned color display. The system demonstrates the unique advantages of a scanned display for the showing of both text and illustrations, of details of different fonts, and of color. Text can be edited, positioned, and changed in size, font, and case; pictures can be positioned, shrunk, enlarged, and cropped. The color of both text and pictures can also be changed in order to guide the designer's eye to essential parts of the page.
Platelet-derived growth factor A-chain synthetic peptide inhibits human glioma xenograft proliferation in nude mice. (1995)

The expression of polypeptide growth factors and their receptors by certain malignant human cell lines and the ability to grow these tumors as xenografts in murine hosts provides a useful setting to investigate the efficacy of antitumor agents. Exon 6 of the platelet-derived growth factor A-chain predicts a highly basic region consisting of 18 amino acids. Previously, we demonstrated that a synthetic peptide bearing this sequence interacts with a large population of binding sites at the cell surface and inhibits the binding and mitogenesis stimulated by several polypeptide growth factors (Khachigian et al J Biol Chem 267: 1660-1666, 1992; Khachigian and Chesterman, J Biol Chem 267: 7478-7482, 1992). In this report, we show that the exon 6 peptide can inhibit the mitogenic response of cultured human U-118 malignant glioma cells to normal human serum. When these cells are grown as subcutaneous xenografts in athymic nude mice, repeated intratumoral administration of the peptide results in dose-dependent growth inhibition. Indeed, injection of 0.48 mg of peptide five times a week abrogated growth during the entire course of treatment. Mouse weight or behavior did not differ significantly between control and treatment groups. Moreover, histologic examination of the tumors following treatment did not indicate necrosis. Thus, the exon 6 peptide can inhibit glioma cell proliferation both in culture and in an animal model without apparent side effects.
Color segmentation using perceptual attributes (2003)

A general approach for achieving color image segmentation using uniform-chromaticity-scale perceptual color attributes is proposed. At first chromatic and achromatic areas in a perceptual IHS color space are defined. Then the image is separated into chromatic and achromatic regions according to the region locations in the color space. 1-D histogram thresholding for each color attribute is performed to split the chromatic and achromatic regions, respectively. Finally the region growing is used to solve the oversegmentation problem. In an experiment the power of the proposed approach is demonstrated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Human odor intensity perception: correlation with frog epithelial adenylate cyclase activity and transepithelial voltage response (1990)

Although a number of odorants are hypothesized to depolarize frog olfactory receptor cells by binding to ciliary glycoproteins which activate membrane-bound G-proteins to induce adenylate cyclase-mediated increases in intracellular cAMP (cyclic adenosine 3',5'-monophosphate), it is not known whether these odorants influence human odor perception via similar mechanisms. In this paper we present evidence derived from odor attribute ranking and multidimensional scaling procedures that the perceived intensity of such odorants to humans is correlated with (a) the amount of adenylate cyclase activity they induce in an in vitro frog olfactory cilia preparation and (b) the magnitude of their influence on the frog transepithelial voltage response or electro-olfactogram (EOG). These observations are in accord with the hypothesis that the perception of the intensity of some odors by humans is associated with cAMP-related epithelial processes and imply that remarkable homologies exist between the intensity-related olfactory receptor mechanisms of frog and man.
Effect of Selected Direct Compression Excipients On the Stability of Acetylsalicylic-Acid Tablets (1995)

The effect of some direct compression excipients (Avicel® PH 101 (I), Avicel PH 101 + mannitol (II), Avicel PH 112 (III), Cellactose® (IV), and Pharmatose® DCL 40 (V)) under different storage conditions (22, 43 and 73% relative humidity, resp.) on the physico-chemical properties and dissolution rate of acetylsalicylic acid tablets was evaluated. Disintegration time, cruching strength, and friability were changed remarkably in the tablet formulations I, II, and III being humidity dependent. Formulations IV and V had no tendency to changes in physical characteristics under storage at different relative humidities for 90 days, whereas the dissolution profiles of samples I, II, and III were increased with increasing humidity. No changes in dissolution rate after storage at different humidities were observed in the lactose-based formulations IV and V. Analytical data (acetylsalicylic acid and salicylic acid content) revealed a high stability of formulations IV and V compared to the others. According to the obtained results, formulations IV and V could be suggested as excipients for high quality acetylsalicylic acid tablets.
Methods for discovering novel motifs in nucleic acid sequences (1989)

We describe a computer tool to aid the discovery of new motifs in nucleic acid sequences. A typical use would be to analyse a set of upstream regions from a family of related genes in order to find possible control sequences. The heart of the method is the creation of dictionaries of related subsequences. These dictionaries can then be analysed to look for the commonest or best-defined subsequences, those that occur in the highest number of different sequences, or for those in equivalent positions within the family. We show the application of the method to a set of E. coli promoter sequences.
Network virtualization architecture (2009)

The tussle between reliability and functionality of the Internet is firmly biased on the side of reliability. New enabling technologies fail to achieve traction across the majority of ISPs. We believe that the greatest challenge is not in finding solutions and improvements to the Internet's many problems, but in how to actually deploy those solutions and re-balance the tussle between reliability and functionality. Network virtualization provides a promising approach to enable the coexistence of innovation and reliability. We describe a network virtualization architecture as a technology for enabling Internet innovation. This architecture is motivated from both business and technical perspectives and comprises four main players. In order to gain insight about its viability, we also evaluate some of its components based on experimental results from a prototype implementation.
Formation of water-in-diesel oil nano-emulsions using high energy method and studying some of their surface active properties (2011)

In this work, formations of water-in-diesel oil nano-emulsions using water/mixed nonionic surfactant/diesel oil system have been studied. The high energy emulsification method was used to form three emulsions using different water contents: 5%, 10% and 14% (v/v) namely; E1, E2 and E3, respectively. These nano-emulsions were stabilized with emulsifiers having different Hydrophilic–Lipophilic Balance (HLB) namely; span 80 (HLB = 4.3), emarol 85 (HLB = 11) and their mixture (SE) with HLB = 10. The effect of water on the droplet size formation has been investigated. The interfacial tension and thermodynamic properties of the individual and emulsifiers blends have been studied. The interfacial tension (γ) measurements at 30 °C were used to determine the critical micelle concentration (CMC) and surface active properties of these emulsifiers. The water droplet sizes were measured by dynamic light scattering (DLS). From the obtained data, it was found that, mean sizes between 19.3 and 39 nm were obtained depending on the water content and concentration of blend emulsifiers (SE). Also, the results show that, the interfacial tension (γ) gives minimum value (10.85 mN/m) for SE comparing with individual emulsifier (17.13 and 12.77 mN/m) for span 80 and emarol 85, respectively. The visual inspection by TEM showed that the obtained results support the data obtained by dynamic light scattering.
Polyhalogeno-aromatic compounds. Part VIII. Reactions of hexabromobenzene with nucleophiles (1969)

Hexabromobenzene unlike its chloro- or fluro-analogues undergoes protodebromination when treated with sodium methoxide in methanol and ethyl methyl ketone to give a mixture of tetrabromobenzenes. With piperidine or ethanolic ammonia debromination and some nucleophilic substitution occurs. Hydrazine gives only 1,2,3,4-tetrabromobenzene while cyclohexyamine or sodium methoxide in pyridine give the corresponding substitution products. Attempts have been made to rationalise these result.
Functional Redundancy of SWI/SNF Catalytic Subunits in Maintaining Vascular Endothelial Cells in the Adult Heart (2012)

BRG1-catalyzed SWI/SNF complexes are particularly important in cardiovascular tissues. However, in contrast to embryonic development, in which Brm does not compensate, Brg1 is required in adult VECs only when Brm is also mutated. These results demonstrate for the first time that Brm functionally compensates for Brg1 in vivo and that there are significant changes in the relative importance of BRG1- and BRM-catalyzed SWI/SNF complexes during the development of an essential cell lineage.
A Unique Set of Micromechanics Equations for High-Temperature Metal Matrix Composites (1988)

A unique set of micromechanics equations is presented for high-temperature metal matrix composites. The set includes expressions to predict mechanical properties, thermal properties, and constituent microstresses for the unidirectional fiber reinforced ply. The equations are derived based on a mechanics of materials formulation assuming a square array unit cell model of a single fiber, surrounding matrix, and an interphase to account for the chemical reaction which commonly occurs between fiber and matrix. A preliminary validation of the equations was performed using three-dimensional finite element analysis. The results demonstrate excellent agreement between properties predicted using the micromechanics equations and properties simulated by the finite element analyses. Implementation of the micromechanics equations as part of an integrated computational capability for nonlinear structural analysis of high-temperature multilayered fiber composites is illustrated.
Acoustic Fingerprints Optimization based on Principal Component Analysis for Indoor Subarea Location (2020)

Researches on indoor acoustic fingerprint localization prove that the time-frequency features of ambient sound have reliable position characterization capabilities. However, the time cost of time-frequency based real-time online positioning is relatively high due to the high dimensionality of time-frequency data. Principal Component Analysis (PCA), is known as dimensionality reduction method, aims to transform multiple indicators into a few comprehensive indicators. In this paper, PCA is adopted to reduce the redundant dimensions of time-frequency fingerprints to help improve the resolution of fingerprints. Beyond this, we prove that only few principal components (less than three principal components) have enough information to ensure the accuracy of indoor subarea location. Experimental results show that the PCA optimized acoustic fingerprint helps increase localization accuracy up to 6%-12% even if it is applied to the simplest classifier, K-Nearest Neighbor (KNN). Such results provide support for realtime machine learning in smart terminals
The Compact Circularly-Polarized Hollow Rectangular Dielectric Resonator Antenna With an Underlaid Quadrature Coupler (2010)

The wideband circularly polarized (CP) dielectric resonator antenna (DRA) is investigated with an underlaid quadrature coupler. The idea is used to realize a CP hollow rectangular DRA. Since the coupler is located beneath the DRA, it does not increase the footprint of the antenna, making the system very compact. The underlaid coupler is placed entirely inside the hollow region of the DRA and, thus, it can be designed easily as if there is no overlaid DRA. Two configurations are considered in this paper. In the first configuration, an external 50-Ω load is used for the matching port of the coupler. For the second one, a strip loaded by the DRA is used to provide a load and, thus, no lumped elements are required in this configuration. In this paper, a network model is also given to aid engineers in designing the proposed integrated DRA. The reflection coefficient, axial ratio, antenna gain, and radiation pattern for each configuration are studied. It was found that wide impedance and axial-ratio bandwidths can be obtained with the proposed CP DRAs. Measurements were carried out to verify the simulations, and reasonable agreement between them was obtained.
Improving Teacher Instructional Behavior (1983)

Improving the productive use of employee time concerns most supervisors in organizational settings. In this paper, a time management program for organizational staff members (nine public school teachers) is described and evaluative results of the use of the program are reported. Using a multiple baseline across schools design, results suggest that training teachers in time management can increase and maintain the amount of time devoted to academic instruction of pupils. Limitations of the study are discussed and directions for future research are noted.
Application of high-resolution spectral analysis for identifying faults in induction motors by means of sound (2011)

Induction motors are critical components for most industries. Induction motor failures may yield an unexpected interruption at the industry plant. Several conventional vibration and current analysis techniques exist by which certain faults in rotating machinery can be identified. Ever since the first motor was built, plant personnel have listened to the noises emanating from machines; with enough experience, a listener may make a fairly accurate estimate of the condition of a machine. Although there are several works that deal with vibration and current analysis for monitoring and detection of faults in induction motors, the analysis of sound signals has not been sufficiently explored as an alternative non-invasive monitoring technique. The contribution of this investigation is the development of a condition monitoring strategy than can make a reliable assessment of the presence of specific fault condition in an induction motor with a single fault present through the analysis of a sound signal. The proposed methodology is based on the multiple-signal classification algorithm for high-resolution spectral analysis. Results show that the proposed methodology of sound analysis could improve standard techniques for induction motor fault detection, enhancing detectability.