gebhart/patrepeval huggingface dataset:
Dynamic non-linear optical processes in semiconductors (1981)

Abstract In this article active non-linear optical effects in semiconductors are reviewed. These processes arise because of the dynamics of excited populations of charge carriers temporarily created in otherwise empty states when a beam of laser radiation is incident on the material. A large number of different effects have been observed in different semiconductor materials recently and the non-linearities cover a wide range of magnitudes both in time-scale and size of non-linearity. The theory and physical concepts relevant to these processes are described and experimental observations using both high power pulsed and low power c.w. lasers are reviewed. Applications in optical bistability, phase conjugation, optical gating and optoelectronic gating are discussed.
The Function of Supervision and Means of Accessing Interview Data (1986)

This article describes a range of methods of accessing data from the counseling interview for use in supervision. Seven methods of access to the interview are identified. Verbal reports, written reports, audiorecording, videorecording, live observation/interaction, co-counseling, and role playing provide access in supervision to past, present or future clinical sessions. These methods are evaluated for six functions of supervision: personal growth, case conceptualization, skills learning, process issues, treatment, and maintenance of standards of service. The suitability of the methods depends on the purpose of the supervision. Differential use of these methods is recommended for supervision.
Hierarchical Mind Map Generation from Video Lectures (2019)

With a steep increase in awareness and advancement in technologies over the past decade the standards and content of curriculum receives constant upgradation. In the current scenario, students often find it exhausting to learn the voluminous matter presented to them. In these cases, it is essential to find an approach beyond conventional means to prove as an aid while studying. One such tool is a Mind Map. Although the tool is proven to be effective, the process of creating a Mind Map is found to be laborious. Our inventive software is designed to obtain useful information from a video lecture. This is done by utilizing the content obtained by crowd sourcing, splitting the video into multiple subtopics and then transcribing the same. The tool then processes this data and extracts keywords relevant to the area of discussion. Following this, the tool organizes these key phrases so that it can be represented as a hierarchical Mind Map. Each node contains necessary phrases and all nodes and these nodes are carefully ordered. Additionally, the Map is made interactive and dynamic in order to enhance the students' experience.
APPENDIX TO INTRODUCTION (2012)

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High level expression of the large subunit of mouse ribonucleotide reductase in a baculovirus system (1993)

The large subunit of ribonucleotide reductase from mouse has been overexpressed in Spodoptera frugiperda cells infected with recombinant baculovirus. The expressed protein was purified by affinity chromatography to apparent homogeneity as determined by SDS-PAGE. The homogeneous protein is recognized in Western blot analysis by a monoclonal antibody raised to the large subunit of ribonucleotide reductase from calf thymus, has the correct N-terminal sequence, and, in the presence of the small subunit of mouse ribonucleotide reductase and nucleoside triphosphate effectors, catalyzes the reduction of both purine and pyrimidine nucleoside diphosphates.
Mesenchymal stem cells inhibit multiple myeloma cells via the Fas/Fas ligand pathway (2013)

These data suggest that Fas/Fas-L-induced MM apoptosis plays a crucial role in the MSC-based inhibition of MM growth. Although whether MSCs inhibit or promote cancer growth remains controversial, the levels of Fas-L expression in MSCs determine, at least partially, the effects of MSCs on MM cell growth.
Increases of plasma eosinophil major basic protein levels late in pregnancy predict onset of labor. (1987)

Major basic protein (MBP), the core of the eosinophil granule, is a potent toxin for parasites and mammalian cells; it also causes histamine release from mast cells and basophils. Plasma levels of MBP are increased in all pregnant women, and MBP has been localized by immunofluorescence to placental X cells and placental-site giant cells. Analyses of plasma MBP levels during pregnancy showed a striking correlation between increases late in the third trimester and spontaneous onset of labor. In one case with premature labor, the plasma MBP level also was increased coincidentally with labor. In contrast, in cases of prolonged gestation in which labor was induced, there were no late increases in MBP levels. Also, uterine contraction during spontaneous labor or oxytocin-induced labor did not cause elevations of plasma MBP. Measurement of plasma MBP levels in pregnancy may be useful for the prediction of labor and for the development of new means of intervention for premature labor and prolonged gestation.
Real-Time Flight Test Evaluation of the GPS Marker Beacon Concept for Category III Kinematic GPS Precision Landing (1993)

A new system based on GPS Marker Beacons (low-power
pseudolite transmitters situated underneath the approach
path) has been developed to provide the highest possible
accuracy, integrity, availability, and continuity for
Category III Precision Landing with the Global
Navigation Satellite System (GNSS). Two new
developments are reported:
l The highly-reliable real-time, centimeter-level
kinematic GPS positioning using the GPS Marker
Beacon concept is evaluated in flight testing.
l A new paradigm for real-time differential GPS is
introduced that eliminates the traditional data link.
Two types of GPS Marker Beacons are considered: the
Doppler Marker and the Omni Marker. The Doppler
Marker is a low-power pseudolite with an independent
time base, integrated with the ground reference receiver
and a traditional data link. The Omni Marker
rebroadcasts each received GPS signal coherently using a
new PRN code. An aircraft receiving both the direct GPS
signal and the new signal rebroadcast from the marker is
capable of differential ranging without a digital data link.
The latency associated with traditional differential GPS is
completely eliminated. These components collectively
comprise the Kinematic GNSS Landing System (KGLS).
To evaluate the performance of the landing system, a
series of approaches were flown in a Piper Dakota.
Comparison with the NASA Ames laser tracker at Crows
Landing demonstrates that the real-time position solutions
obtained with GPS agree to within the 30 cm accuracy
specification of the laser tracker. In independent testing at
Palo Alto Airport, altitude accuracy above the runway is
established to 10 cm using a laser altimeter.
UN PETIT AIR ANGLO-SAXOPHONE (2003)

Journal Article UN PETIT AIR ANGLO-SAXOPHONE Get access KEN GEORGE KEN GEORGE London Search for other works by this author on: Oxford Academic Google Scholar French Studies Bulletin, Volume 24, Issue 89, WINTER 2003, Pages 18–20, https://doi.org/10.1093/frebul/24.89.18 Published: 01 December 2003
Hydrogen-Bonding Strength in the Blends of Polybenzimidazole with BTDA- and DSDA-Based Polyimides (1997)

Blends of solutions of poly[2,2‘-(m-phenylene)-5,5‘-bibenzimidazole] (PBI) with poly(amic acids) (PAA's) synthesized from BTDA (3,3‘,4,4‘-tetracarboxybenzophenone dianhydride) and DSDA (3,3‘,4,4‘-tetracarboxydiphenyl sulfone dianhydride) with 3,3‘-DDSO2 (3,3‘-diaminodiphenyl sulfone), 4,4‘-DDSO2 (4,4‘-diaminodiphenyl sulfone), 4,4‘-MDA (4,4‘-methylenedianiline), and 4,4‘-ODA (4,4‘-oxydianiline) were prepared in DMAc solvent and transformed into PBI/polyimide (PI) blends by curing at higher temperatures than the Tgs of the blends. The blend systems used in this study were all miscible; evidences for miscibility were optically clear film, a synergistic single Tgs at all compositions, and frequency shifts of the functional groups intermediate between those of the constituents. The strength of intermolecular interaction between PBI and various polyimides were measured by means of DSC, DMTA, and FT-IR. From the analyzed data based on the Tg diagram, the Fox equation, the k values in Gordon−Taylor equation, and the frequency shifts of the functional groups, interpretation was consistent, implying that the strengths of hydrogen bonding display relatively higher in the BTDA-based blends than the DSDA systems. This difference may be arised from the electron affinity in the spacer between benzophenone carbonyl in BTDA and symmetric sulfone in DSDA.
Digital image processing for photo-reconnaissance applications (1972)

Digital image-processing techniques developed for processing pictures from NASA space vehicles are analyzed in terms of enhancement, quantitative restoration, and information extraction. Digital filtering, and the action of a high frequency filter in the real and Fourier domain are discussed along with color and brightness.
In vitro mimicry of metabolic oxidation reactions by electrochemistry/mass spectrometry (2000)

The aim of these studies was to investigate the scope and limitations of electrochemistry on-line with mass spectrometry as a quick and convenient way to mimic phase I oxidative reactions in drug metabolism. A compound with previously reported in vitro and in vivo metabolism, the dopamine agonist 2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin, was examined in an electrochemistry/mass spectrometry (EC/MS) system. The previously reported N-dealkylation was mimicked by the electrochemical cell while the oxidation of the phenol function was not fully mimicked by the EC/MS system, since the catechol and p-hydroquinone formed were immediately oxidized to the corresponding quinones. Since cytochrome P450 isoenzymes are the most important enzymes in phase I oxidative metabolism, two standard substrates used for the characterization of those enzymes, lidocaine and 7-ethoxycoumarin, were tested in the EC/MS system. The electrochemical cell was capable of mimicking the N-dealkylation of lidocaine but, under the conditions used in our experiments, the O-deethylation of 7-ethoxycoumarin could not be simulated in the electrochemical cell.
The reaction of amino-imidazoles, -pyrazoles and -triazoles with α,β-unsaturated nitriles (2005)

The reactions of α,β-unsaturated nitriles (1, 9, 12) as bielectrophiles with aminoazoles (2, 4, 6) as binu-cleophiles were investigated. Acrylonitrile (1) reacts almost exclusively in a chemoselective Michael-type addition yielding the substituted azoles 3, 5 and 7, respectively. Cinnamonitriles 9a,b behave in a similar way, but the free CN group adds a second molecule 4 yielding 10a,b and its cyclocondensation product 11a,b as minor component. The attempted formation of azolopyrimidines is best achieved by the reaction of the benzylidenemalononitriles 12a - f with 2 or 4. The process is chemo- and regioselective. The structure determinations were based on NMR measurements including DEFT, COSY, ROESY, HMQC and HMBC techniques and correct earlier suggestions.
Visualization of Thermal Fields in Saturated Porous Media by the Christiansen Effect (1973)

A quantitative optical method has been demonstrated for the study of two-dimensional thermal phenomena in saturated porous media, making possible the visualization of a certain number of isotherms as bright lines of different colors. A study of the characteristics of Christiansen filters has been carried out in order to determine the experimental conditions most favorable to the use of this method. Examples of its application are given relative to phenomena of natural convection.
Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression (2016)

Interleukin-6 (IL-6) is a key pathogenic cytokine in multiple autoimmune diseases including rheumatoid arthritis and multiple sclerosis, suggesting that dysregulation of the IL-6 pathway may be a common feature of autoimmunity. The role of IL-6 in type 1 diabetes (T1D) is not well understood. We show that signal transducer and activator of transcription 3 (STAT3) and STAT1 responses to IL-6 are significantly enhanced in CD4 and CD8 T cells from individuals with T1D compared to healthy controls. The effect is IL-6-specific because it is not seen with IL-10 or IL-27 stimulation, two cytokines that signal via STAT3. An important determinant of enhanced IL-6 responsiveness in T1D is IL-6 receptor surface expression, which correlated with phospho-STAT3 levels. Further, reduced expression of the IL-6R sheddase ADAM17 in T cells from patients indicated a mechanistic link to enhanced IL-6 responses in T1D. IL-6-induced STAT3 phosphorylation was inversely correlated with time from diagnosis, suggesting that dysregulation of IL-6 signaling may be a marker of early disease. Finally, whole-transcriptome analysis of IL-6-stimulated CD4(+) T cells from patients revealed previously unreported IL-6 targets involved in T cell migration and inflammation, including lymph node homing markers CCR7 and L-selectin. In summary, our study demonstrates enhanced T cell responses to IL-6 in T1D due, in part, to an increase in IL-6R surface expression. Dysregulated IL-6 responsiveness may contribute to diabetes through multiple mechanisms including altered T cell trafficking and indicates that individuals with T1D may benefit from IL-6-targeted therapeutic intervention such as the one that is being currently tested (NCT02293837).
Expression of pancreatic secretory trypsin inhibitor gene in neoplastic tissues (1987)

Expression of the human pancreatic secretory trypsin inhibitor (PSTI) gene was examined in 24 cases of neoplastic tissues by Northern blot analyses. In three cases of lung adenocarcinoma and one case of sigmoid colon polyp, we detected transcripts which hybridized to the human PSTI cDNA probe. cDNA libraries were constructed using mRNAs of the two PSTI‐positive tumor tissues. Two PSTI cDNA clones were obtained from each sample. Sequencing analyses showed that they were completely identical with that of pancreatic PSTI cDNA which had been reported [(1985) Biochem. Biophys. Res. Commun. 132, 605–612]. Southern blot analyses showed that the elevated expression of PSTI in neoplastic tissues was accompanied by neither PSTI gene amplification nor rearrangements.
An Empirical Comparison of Alternative Models of the Short‐Term Interest Rate (1992)

ABSTRACT We estimate and compare a variety of continuous‐time models of the short‐term riskless rate using the Generalized Method of Moments. We find that the most successful models in capturing the dynamics of the short‐term interest rate are those that allow the volatility of interest rate changes to be highly sensitive to the level of the riskless rate. A number of well‐known models perform poorly in the comparisons because of their implicit restrictions on term structure volatility. We show that these results have important implications for the use of different term structure models in valuing interest rate contingent claims and in hedging interest rate risk.
Synthesis of Poly(p-dioxanone) Catalyzed by Zn L-Lactate under Microwave Irradiation and Its Application in Ibuprofen Delivery (2010)

Microwave-assisted ring-opening polymerization (ROP) of p-dioxanone (PDO) catalyzed by Zn L-lactate (Znlac(2)) was investigated and the purified product was characterized by (1)H-NMR. When the ROP of PDO was carried out at 100 degrees C for 6.5 h, the viscosity-average molecular weight (M(v)) of poly(p-dioxanone) (PPDO) reached 53.2 kg/mol. The kinetics of ring-opening polymerization of PDO under microwave irradiation were investigated and the polymerization reaction was accurately first-order with respect to monomer concentration. The reaction rate was greatly accelerated by microwave irradiation, compared with conventional heating. The resultant PPDO was used as carrier and drug-release systems were prepared using ibuprofen (IBU) as model drug with 10, 15 and 20% loading. The release behavior of the systems was investigated in phosphate buffer solution at 37 degrees C and the release of IBU from the system was sustained and steady. The resultant PPDO could be well used as the carrier for the delivery drug.
Protein pathway and complex clustering of correlated mRNA and protein expression analyses in <i>Saccharomyces</i> <i>cerevisiae</i> (2003)

The mRNA and protein expression in Saccharomyces cerevisiae cultured in rich or minimal media was analyzed by oligonucleotide arrays and quantitative multidimensional protein identification technology. The overall correlation between mRNA and protein expression was weakly positive with a Spearman rank correlation coefficient of 0.45 for 678 loci. To place the data sets in a proper biological context, a clustering approach based on protein pathways and protein complexes was implemented. Protein expression levels were transcriptionally controlled for not only single loci but for entire protein pathways (e.g., Met, Arg, and Leu biosynthetic pathways). In contrast, the protein expression of loci in several protein complexes (e.g., SPT, COPI, and ribosome) was posttranscriptionally controlled. The coupling of the methods described provided insight into the biology of S. cerevisiae and a clustering strategy by which future studies should be based.
Kinetics of hydrogen production from methyl viologen radicals on colloidal platinum (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetics of hydrogen production from methyl viologen radicals on colloidal platinumM. S. Matheson, P. C. Lee, D. Meisel, and E. PelizzettiCite this: J. Phys. Chem. 1983, 87, 3, 394–399Publication Date (Print):February 1, 1983Publication History Published online1 May 2002Published inissue 1 February 1983https://pubs.acs.org/doi/10.1021/j100226a008https://doi.org/10.1021/j100226a008research-articleACS PublicationsRequest reuse permissionsArticle Views464Altmetric-Citations63LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Effect of Month-Long Treatment with Oral N-Acetylcysteine on the Oxidative Stress and Proteinuria in Patients with Diabetic Nephropathy a Pilot Study (2010)

N-acetylcysteine in moderate doses given over a month did not have significant effect on the overall oxidative stress in patients with DN and did not reduce proteinuria.
Insulin stimulates the generation from hepatic plasma membranes of modulators derived from an inositol glycolipid. (1986)

Insulin binding to plasma membrane receptors results in the generation of substances that acutely mimic the actions of the hormone on certain target enzymes. Two such substances, which modulate the activity of the high-affinity cAMP phosphodiesterase (EC 3.1.4.17), have been purified from hepatic plasma membranes. The two have similar properties and activities but can be resolved by ion-exchange chromatography and high-voltage electrophoresis. They exhibit a net negative charge, even at pH 1.9, and an apparent molecular weight of approximately 1400. The generation of these substances from membranes by insulin can be reproduced by addition of a phosphatidylinositol-specific phospholipase C purified from Staphylococcus aureus. This enzyme is known to selectively hydrolyze phosphatidylinositol and release from membranes several proteins that are covalently linked to phosphatidylinositol by a glycan anchor. Both enzyme-modulating substances appear to be generated by the phosphodiesterase cleavage of a phosphatidylinositol-containing glycolipid precursor that has been characterized by thin-layer chromatography. Some of the chemical properties of these substances have been examined. They appear to be related complex carbohydrate-phosphate substances containing glucosamine and inositol. These findings suggest that insulin may activate a selective phospholipase activity that hydrolyzes a membrane phospholipid, releasing a carbohydrate-containing molecule that regulates cAMP phosphodiesterase and perhaps other insulin-sensitive enzymes.
CO-OCCURRENCE NETWORK OF REUTERS NEWS (2008)

Networks describe various complex natural systems including social systems. We investigate the social network of co-occurrence in Reuters-21578 corpus, which consists of news articles that appeared in the Reuters newswire in 1987. People are represented as vertices and two persons are connected if they co-occur in the same article. The network has small-world features with power-law degree distribution. The network is disconnected and the component size distribution has power-law characteristics. Community detection on a degree-reduced network provides meaningful communities. An edge-reduced network, which contains only the strong ties has a star topology. "Importance" of persons are investigated. The network is the situation in 1987. After 20 years, a better judgment on the importance of the people can be done. A number of ranking algorithms, including Citation count and PageRank, are used to assign ranks to vertices. The ranks given by the algorithms are compared against how well a person is represented in Wikipedia. We find up to medium level Spearman's rank correlations. A noteworthy finding is that PageRank consistently performed worse than the other algorithms. We analyze this further and find reasons.
Fluorescence-Guided Surgery and Fluorescence Laparoscopy for Gastrointestinal Cancers in Clinically-Relevant Mouse Models (2013)

There are many challenges that face surgeons when attempting curative resection for gastrointestinal cancers. The ability to properly delineate tumor margins for complete resection is of utmost importance in achieving cure and giving the patient the best chance of prolonged survival. Targeted tumor imaging techniques have gained significant interest in recent years to enable better identification of tumor lesions to improve diagnosis and treatment of cancer from preoperative staging modalities to optimizing the surgeon's ability to visualize tumor margins at the initial operation. Using unique characteristics of the tumor to fluorescently label the tissue can delineate tumor margins from normal surrounding tissue, allowing improved precision of surgical resection. In this paper, different methods of fluorescently labeling native tumor are discussed as well as the development of fluorescence laparoscopy and the potential role for fluorescence-guided surgery in the treatment of gastrointestinal cancers.