gebhart/patrepeval huggingface dataset:
Catalysed recombination of CO and O<sub>2</sub>in sealed CO<sub>2</sub>TEA laser gases at temperatures down to -27 degrees C (1983)

An experimental determination has been made of the rates at which SnO2-Pd and SnO2-Pt catalysts recombine CO and O2 at low concentrations in a basic gas mixture of CO2, N2 and He at a total pressure of one atmosphere. Significant rates were measured over the whole temperature range of the investigation (-27 degrees C to 44 degrees C). This information has enabled these catalysts to be used, unheated, in sealed CO2 TEA lasers operating with mixtures of these gases containing high concentrations of CO2. Their use has overcome the most important factor previously limiting the life of such lasers (especially at high pulse repetition frequencies), i.e. the generation of O2 and CO by the dissociation of CO2 during operation.
AN ANTIMALARIAL ALKALOID FROM HYDRANGEA. VI. A SECOND SYNTHESIS OF 3-[β-KETO-γ-(2-PIPERIDYL)-PROPYL]-4-QUINAZOLONE (1952)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAN ANTIMALARIAL ALKALOID FROM HYDRANGEA. VI. A SECOND SYNTHESIS OF 3-[β-KETO-γ-(2-PIPERIDYL)-PROPYL]-4-QUINAZOLONEB. R. BAKER, MERLE V. QUERRY, ROBERT E. SCHAUB, and JAMES H. WILLIAMSCite this: J. Org. Chem. 1952, 17, 1, 58–67Publication Date (Print):January 1, 1952Publication History Published online1 May 2002Published inissue 1 January 1952https://pubs.acs.org/doi/10.1021/jo01135a007https://doi.org/10.1021/jo01135a007research-articleACS PublicationsRequest reuse permissionsArticle Views153Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
LEGO-Like Microassembly Using Reversible Dry Adhesion (2016)

When I was a kid, I was fascinated by watching water striders glide on the water and would wonder: why do they not drown but instead play, standing effortlessly on the water? This is undoubtedly a common question among curious children. The simplest answer would be "because the insect is very small and light." So then, why are smaller things better able to float on the water? An aircraft carrier can easily float on the sea too, although it is extremely large.
Self oscillated PWM converter with impulse resonant soft-switching (2003)

A novel self oscillated PWM converter with an impulse resonant soft-switching using a saturable inductor is developed. The converter has the switches operated soft-switching by impulse charging and discharging the parasitic capacitance of the main switches and also driving circuit of the switches. The dead time for impulse resonant soft-switching is always automatically adjusted. The complete operating principle, theoretical analysis and experimental result on the proposed converter are provided.
Theory of electronically phased coherent beam combination without a reference beam (2006)

The first theory for two novel coherent beam combination architectures that are the first electronic beam combination architectures that completely eliminate the need for a separate reference beam are presented. Detailed theoretical models are developed and presented for the first time.
Identification of mediators stimulating proliferation and matrix synthesis of rat pancreatic stellate cells (2001)

The aim of this study was to identify fibrogenic mediators stimulating activation, proliferation, and/or matrix synthesis of rat pancreatic stellate cells (PSC). PSC were isolated from the pancreas of normal Wistar rats and from rats with cerulein pancreatitis. Cell activation was demonstrated by immunofluorescence microscopy of smooth muscle alpha-actin (SMA) and real-time quantitative RT-PCR of SMA, fibronectin, and transforming growth factor (TGF)-beta(1). Proliferation was measured by bromodeoxyuridine incorporation. Matrix synthesis was demonstrated on the protein and mRNA level. Within a few days in primary culture, PSC changed their phenotype from fat-storing to SMA-positive myofibroblast-like cells expressing platelet-derived growth factor (PDGF) alpha- and PDGF beta-receptors. TGF-beta(1) and tumor necrosis factor (TNF)-alpha accelerated the change in the cells' phenotype. Addition of 50 ng/ml PDGF and 5 ng/ml basic fibroblast growth factor (bFGF) to cultured PSC significantly stimulated cell proliferation (4.37 +/- 0.49- and 2.96 +/- 0.39-fold of control). Fibronectin synthesis calculated on the basis of DNA was stimulated by 5 ng/ml bFGF (3.44 +/- 1.13-fold), 5 ng/ml TGF-beta(1) (2.46 +/- 0.89-fold), 20 ng/ml PDGF (2.27 +/- 0.68-fold), and 50 ng/ml TGF-alpha (1.87 +/- 0.19-fold). As shown by RT-PCR, PSC express predominantly the splice variant EIII-A of fibronectin. Immunofluorescence microscopy and Northern blot confirmed that in particular bFGF and TGF-beta(1) stimulated the synthesis of fibronectin and collagens type I and III. In conclusion, our data demonstrate that 1) TGF-beta(1) and TNF-alpha accelerate the change in the cell phenotype, 2) PDGF represents the most effective mitogen, and 3) bFGF, TGF-beta(1), PDGF, and, to a lesser extent, TGF-alpha stimulate extracellular matrix synthesis of cultured rat PSC.
Grouping variables into multiport memories for data path synthesis (1992)

Grouping registers into register files for efficiently implementing large VLSI chips, based on multiport memories, is being used in the design of many high-speed RISC and superscalar processors. An efficient design methodology for grouping variables into multiport memories, which is an essential step for multiport memory-based data path synthesis, is presented. The technique not only groups variables into a minimum number of multiport memory modules, but also simultaneously minimizes the number of registers in each memory module. The minimization problem has been formulated as a zero-one integer linear programming problem. Experiments on benchmarks show very promising results.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Visible Light-Driven Hydrogen Production from Aqueous Protons Catalyzed by Molecular Cobaloxime Catalysts (2009)

A series of cobaloxime complexes([Co(dmgH)(2)pyCl] (1), [Co(dmgH)(2)(4-COOMe-py)Cl] (2), [Co(dmgH)(2)(4-Me(2)N-py)Cl] (3), [Co(dmgH)(dmgH(2))Cl(2)] (4), [Co(dmgH)(2)(py)(2)](PF(6)) (5), [Co(dmgH)(2)(P(n-Bu)(3))Cl] (6), and [Co(dmgBF(2))(2)(OH(2))(2)] (7), where dmgH = dimethylglyoximate monoanion, dmgH(2) = dimethylglyoxime, dmgBF(2) = (difluoroboryl)dimethylglyoximate anion, and py = pyridinewere synthesized and studied as molecular catalysts for the photogeneration of hydrogen from systems containing a Pt terpyridyl acetylide chromophore and triethanolamine (TEOA) as a sacrificial donor in aqueous acetonitrile. All cobaloxime complexes 1-7 are able to quench the luminescence of the Pt(II) chromophore [Pt(ttpy)(CCPh)]ClO(4) (C1) (ttpy = 4'-p-tolyterpyridine). The most effective electron acceptor for hydrogen evolution is found to be complex 2, which provides the fastest luminescence quenching rate constant for C1 of 1.7 x 10(9) M(-1) s(-1). The rate of hydrogen evolution depends on many factors, including the stability of the catalysts, the driving force for proton reduction, the relative and absolute concentrations of system components (TEOA, Co molecular catalyst, and sensitizer), and the ratio of MeCN/water in the reaction medium. For example, when the concentration of TEOA increases, the rate of H(2) photogeneration is faster and the induction period is shorter. Colloidal cobalt experiments and mercury tests were run to verify that the system is homogeneous and that catalysis does not occur from in situ generated colloidal particles during photolysis. The most effective system examined to date consists of the chromophore C1 (1.1 x 10(-5) M), TEOA (0.27 M), and catalyst complex 1 (2.0 x 10(-4) M) in a MeCN/water mixture (24:1 v/v, total 25 mL); this system has produced approximately 2150 turnovers of H(2) after only 10 h of photolysis with lambda > 410 nm.
Optimal attack and reinforcement of a network (1985)

In a nonnegative edge-weighted network, the weight of an edge represents the effort required by an attacker to destroy the edge, and the attacker derives a benefit for each new component created by destroying edges. The attacker may want to minimize over subsets of edges the difference between (or the ratio of) the effort incurred and the benefit received. This idea leads to the definition of the “strength” of the network, a measure of the resistance of the network to such attacks. Efficient algorithms for the optimal attack problem, the problem of computing the strength, and the problem of finding a minimum cost “reinforcement” to achieve a desired strength are given. These problems are also solved for a different model, in which the attacker wants to separate vertices from a fixed central vertex.
Asymptomatic Congenital Chagas' Disease in a 5-Year-Old Child (1981)

A case of asymptomatic Chagas' disease is a 5-year-old boy is described. The boy was born in Romania in 1975 and had never visited an area where Chagas' disease is endemic. It is important bear in mind the possibility of transplacental transmission, in view of increasing number of immigrants and refugees coming from South and Central America.
Effects of Tool Positions on Borehole Acoustic Measurements: a Stretched Grid Finite Difference Approach (2003)

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric, and Planetary Sciences, 2003.
PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells (2018)

The spindle assembly checkpoint (SAC) acts as a molecular safeguard in ensuring faithful chromosome transmission during mitosis, which is regulated by a complex interplay between phosphatases and kinases including PLK1. Adenomatous polyposis coli (APC) germline mutations cause aneuploidy and are responsible for familial adenomatous polyposis (FAP). Here we study the role of PLK1 in colon cancer cells with chromosomal instability promoted by APC truncation (APC-ΔC). The expression of APC-ΔC in colon cells reduces the accumulation of mitotic cells upon PLK1 inhibition, accelerates mitotic exit and increases the survival of cells with enhanced chromosomal abnormalities. The inhibition of PLK1 in mitotic, APC-∆C-expressing cells reduces the kinetochore levels of Aurora B and hampers the recruitment of SAC component suggesting a compromised mitotic checkpoint. Furthermore, Plk1 inhibition (RNAi, pharmacological compounds) promotes the development of adenomatous polyps in two independent Apc <sup>Min/+</sup> mouse models. High PLK1 expression increases the survival of colon cancer patients expressing a truncated APC significantly.
CMOS image sensors: electronic camera-on-a-chip (1997)

CMOS active pixel sensors (APS) have performance competitive with charge-coupled device (CCD) technology, and offer advantages in on-chip functionality, system power reduction, cost, and miniaturization. This paper discusses the requirements for CMOS image sensors and their historical development, CMOS devices and circuits for pixels, analog signal chain, and on-chip analog-to-digital conversion are reviewed and discussed.
The Internet of Things in the Cloud (2012)

Although the Internet of Things (IoT) is a vast and dynamic territory that is evolving rapidly, there has been a need for a book that offers a holistic view of the technologies and applications of the entire IoT spectrum. Filling this void, The Internet of Things in the Cloud: A Middleware Perspective provides a comprehensive introduction to the Io
A sheep model for continuous intrathecal infusion of test substances (1999)

Pharmaceutical research and new drug development rely extensively on animal research. The development of novel agents for intrathecal administration requires preclinical studies of toxic effects in an animal model. We have developed a nonrodent animal model for this purpose. Our sheep model: 1 Is an animal whose neural axis is similar to the human 2 Allows for the percutaneous placement of intrathecal catheters 3 Has minimal possibilities of infection because the infusion system is totally implanted 4 Provides continuous infusion of the test agent 5 Generates behavioral, motor, neurological and histopathological information so that safety guidelines can be established prior to preclinical studies.
A width-recursive depth-first tree search approach for the design of discrete coefficient perfect reconstruction lattice filter bank (2003)

The lattice structure two-channel orthogonal filter bank structurally guarantees the perfect reconstruction (PR) property. Thus, it is eminently suitable for hardware realization even under severe coefficient quantization condition. Nevertheless, its frequency response is still adversely affected by coefficient quantization. In this paper, a novel recursive-in-width depth-first tree search technique is presented for the design of lattice structure PR orthogonal filter banks subject to discrete coefficient value constraint. A frequency-response deterioration measure is developed to serve as a branching criterion. At any node, the coefficient which will cause the largest deterioration in the frequency response of the filter when quantized is selected for branching. The improvement in the frequency response ripple magnitude achieved by our algorithm over that by simple rounding of coefficient values differs widely from example to example ranging from a fraction of a decibel to over 10 dB.
Advanced Server Virtualization (2006)

Presenting practical guidelines and examples, Advanced Server Virtualization emphasizes design, implementation, and management from both a technical and consultative point of view. It features step-by-step guidelines for planning, deployment, installing, configuring, and creating virtual servers. Covering Microsoft Virtual Server and VMware, it addresses platform-specific virtualization features such as virtual machines, hard drives, networking, and resource management. It offers best practices that allow users to avoid common pitfalls and achieve success faster during server virtualization implementations. It also discusses software licensing issues and the cost-benefits of deploying virtual servers.
[Synthesis and antitumor activity of S-hexyl(heptyl) substituted ethanethioate derivatives]. (2014)

To simplify the macrocyclic fragment and to modify the zinc binding group of the natural product apicidin, two series of S-hexyl (heptyl) ethanethioate derivatives were designed and synthesized. Twenty-six compounds were synthesized and confirmed with 1H NMR, IR, MS and HR-MS spectrum, which were not reported. Take vorinostat as control, their antiporliferative activities against cancer cell lines, MCF-7 and HL-60, were tested with MTT assay or trypan blue staining method. Generally in both series it was found that, the chiral carbon atom at 7 position is not necessary, compounds II-1, II-3, II-6 and II-13 showed good activity on HL-60 cells in vitro, with the IC50 values less than 10 micromol x L(-1). II-7 and II-8 showed stronger activity against MCF-7 than Vorinostat, with the IC50 of 3.19 and 6.29 micromol x L(-1), respectively.
Novel Pharmacology of Substance K-Binding Sites: a Third Type of Tachykinin Receptor (1984)

The tachykinins are a family of peptides with the carboxyl terminal amino acid sequence Phe-X-Gly-Leu-Met-NH2. Three major mammalian tachykinins have been identified--substance K, neuromedin K, and substance P--but only two tachykinin receptors have been postulated. Three tachykinins were labeled with radioiodinated Bolton-Hunter reagent and their binding characteristics were determined in crude membrane suspensions from several tissues. In cerebral cortex labeled eledoisin exhibited high-affinity binding that was inhibited by tachykinins in a manner indicating a definitive SP-E receptor site. In gastrointestinal smooth muscle and bladder, high-affinity binding of labeled substance P was inhibited in a pattern indicating a definitive SP-P site. In intestinal smooth muscle and bladder, however, labeled substance K and labeled eledoisin were both bound in a pattern indicating a preference for substance K itself. The results suggest the existence of three distinct types of tachykinin receptors: SP-P, SP-E, and SP-K.
Hospitalizations, costs, and outcomes of severe sepsis in the United States 2003 to 2007 (2011)

The increase in the number of hospitalizations for severe sepsis coupled with declining in-hospital mortality and declining geometric mean cost per case may reflect improvements in care or increases in discharges to skilled nursing facilities; however, these findings more likely represent changes in documentation and hospital coding practices that could bias efforts to conduct national surveillance.
Perceptual evaluation of cartoon physics (2008)

People have been using stylistic methods in classical animation for many years and such methods have also been recently applied in 3D Computer Graphics. We have developed a method to apply squash and stretch cartoon stylisations to physically based simulations in real-time. In this paper, we present a perceptual evaluation of this approach in a series of experiments. Our hypotheses were: that stylised motion would improve user Accuracy (trajectory prediction); that user Attention would be drawn more to objects with cartoon physics; and that animations with cartoon physics would have more Appeal. In a task that required users to accurately predict the trajectories of bouncing objects with a range of elasticities and varying degrees of information, we found that stylisation significantly improved user accuracy, especially for high elasticities and low information. To assess attention, many simulated objects were shown to participants on which words appeared at random, the task being to speak and remember them. Our results do not confirm that attention can be directed in such a scenario using cartoon physics. However, a game with cartoon physics was chosen to be more appealing almost twice as often as one with no stylisation applied. We conclude that stylised motion can be a valuable tool to improve physically based animations.
Skyrmion Lattice in a Chiral Magnet (2009)

Skyrmions represent topologically stable field configurations with particle-like properties. We used neutron scattering to observe the spontaneous formation of a two-dimensional lattice of skyrmion lines, a type of magnetic vortex, in the chiral itinerant-electron magnet MnSi. The skyrmion lattice stabilizes at the border between paramagnetism and long-range helimagnetic order perpendicular to a small applied magnetic field regardless of the direction of the magnetic field relative to the atomic lattice. Our study experimentally establishes magnetic materials lacking inversion symmetry as an arena for new forms of crystalline order composed of topologically stable spin states.
Cycle-Resolved Multipoint Ionization Probe Measurements in a Spark Ignition Engine (1989)

<div class="htmlview paragraph">Ionization probes installed in the head gasket of a spark ignition engine are used to measure the cycle-resolved arrival time of the flame at eight discrete points at the perimeter of the cylinder bore. Simultaneous data acquisition of the ionization probe and cylinder pressure measurements permits the flame burn pattern, the combustion rate, and the cyclic variability of these quantities to be observed on a video monitor m real-time as engine operating parameters are varied. To demonstrate the technique, measurements are presented for uniformly-spaced and clustered arrangements of ionization probes and differing conditions of fluid motion, spark location, spark plug configuration, and equivalence ratio.</div>
Structural basis for norovirus neutralization by an HBGA blocking human IgA antibody (2016)

Human noroviruses (HuNoVs) cause sporadic and epidemic gastroenteritis worldwide. They are classified into two major genogroups (GI and GII), with each genogroup further divided into multiple genotypes. Susceptibility to these viruses is influenced by genetically determined histo-blood group antigen (HBGA) expression. HBGAs function as cell attachment factors by binding to a surface-exposed region in the protruding (P) domain of the capsid protein. Sequence variations in this region that result in differential HBGA binding patterns and antigenicity are suggested to form a basis for strain diversification. Recent studies show that serum antibodies that block HBGA binding correlate with protection against illness. Although genogroup-dependent variation in HBGA binding specificity is structurally well characterized, an understanding of how antibodies block HBGA binding and how genotypic variations affect such blockade is lacking. Our crystallographic studies of the GI.1 P domain in complex with the Fab fragment of a human IgA monoclonal antibody (IgA 5I2) with HBGA blocking activity show that the antibody recognizes a conformational epitope formed by two surface-exposed loop clusters in the P domain. The antibody engulfs the HBGA binding site but does not affect its structural integrity. An unusual feature of the antigen recognition by IgA 5I2 is the predominant involvement of the CDR light chain 1 in contrast to the commonly observed CDR heavy chain 3, providing a unique perspective into antibody diversity in antigen recognition. Identification of the antigenic site in the P domain shows how genotypic variations might allow escape from antibody neutralization and exemplifies the interplay between antigenicity and HBGA specificity in HuNoV evolution.
Length Dependence of Charge Transport in Nanoscopic Molecular Junctions Incorporating a Series of Rigid Thiol-Terminated Norbornylogs (2005)

Four tetrathiol-terminated norbornane homologues were synthesized and self-assembled monolayers (SAMs) of these molecules were formed on Au via adsorption from CH2Cl2. SAMs were characterized structurally via spectroscopic ellipsometry (SE), reflection-absorption infrared spectroscopy (RAIRS), Rutherford backscattering spectrometry (RBS), and X-ray photoelectron spectroscopy (XPS). Results of these analyses show that the rigid norbornylogs form monolayers that have a surface coverage slightly lower than that of alkanethiols, and that they exhibit a nonmonotonic dependence of film thickness on molecular length. Nanoscale molecular junctions incorporating these SAMs were formed and characterized electrically using conducting probe atomic force microscopy (CP-AFM). The resistances of these junctions scale exponentially with the contour length of the molecules, with beta = 0.9 A(-1), consistent with a nonresonant tunneling mechanism. Further, the resistance of norbornyl SAMs correlates well with the resistance of alkanedithiol SAMs of similar length, suggesting that the norbornyl molecules form sulfur-metal bonds on both ends of the junction.