gebhart/patrepeval huggingface dataset:
Predicting Abnormal Microbial Population Levels in the Vaginal Ecosystem (1994)

AbstractWe have attempted to predict the occurrence of abnormal microbial concentrations in the vaginal ecosystem by fitting a statistical model to anin vivo data set containing qualitative and quantitative information from women with known normal and abnormal microbial population levels. Predictive factors were selected by multiple regression with backwards elimination and included pH and concentrations of total aerobic bacteria, Staphylococcus spp., Lactobacillus spp. and Prevotella spp. The resulting model calculates the likelihood of an abnormal microbiota, using these factors for a given individual. Potentially, this model can be employed for clinical studies in which determining the effect of a particular alteration of the vaginal environment is important.Key Words: ModelVagina microbiotaNormal ecosystemStatistics
A generic traceability framework for facet-based traceability data extraction in model-driven software development (2010)

Traceability of artefacts induces the means of understanding the complexity of logical relations existing among artefacts, that are created during software development. In turn, this provides the necessary knowledge for reasoning about the quality of software. With the inception of Model-Driven Software Engineering, the advantage of generating traceability information automatically, eases the problem of creating and maintaining trace links, which is a labor intensive task, when done manually. Yet, there is still a wide range of open challenges in existing traceability solutions and a need to consolidate traceability domain knowledge. This paper proposes a generic traceability framework for augmenting arbitrary model transformation approaches with a traceability mechanism. Essentially, this augmentation is based on a domain-specific language for traceability, accounting for facet-based data extraction.
CMOS-Compatible Hybrid III-V/Si Photodiodes Using a Lateral Current Collection Scheme (2018)

The CMOS-compatible front-end integration of ultra-compact lateral current collection III-V/Si photodetectors on a Silicon Photonics platform is demonstrated for the first time. The novel waveguide-coupled photodiodes show sub-nA dark current, ultra-low capacitance, a high responsivity, and data transmission at 25Gbps.
A Generalized Method for Evaluating the Metallic-to-Semiconducting Ratio of Separated Single-Walled Carbon Nanotubes by UV−vis−NIR Characterization (2010)

A general and useful method has been developed to evaluate the metallic-to-semiconducting (M/S) ratio for separated single-walled carbon nanotubes (SWNTs). By virtue of measuring UV−vis−NIR spectra of a variety of solutions with different ratios of metallic-rich to semiconducting-rich SWNTs, the commercial IsoNanotubes samples as well as metallic-rich HiPCO SWNTs (HiPCO-M) separated by an Agarose gel method have been evaluated. Values of 99.5% metallic contents for IsoNanotubes-M, 98.9% semiconducting contents for IsoNanotubes-S, and 1.24 for the absorption coefficient of IsoNanotubes, whereas 80.4% metallic contents for HiPCO-M and 1.05 for the absorption coefficient of HiPCO SWNTs were obtained. This method does not need pure metallic (M-) or semiconducting (S-) SWNTs as references. Furthermore, we found that this method can also be applied to evaluate the M/S ratio for any SWNT samples.
Phrase-Based Statistical Translation of Programming Languages (2014)

Phrase-based statistical machine translation approaches have been highly successful in translating between natural languages and are heavily used by commercial systems (e.g. Google Translate).
Attosecond physics (2009)

Intense ultrashort light pulses comprising merely a few wave cycles became routinely available by the turn of the millennium. The technologies underlying their production and measurement as well as relevant theoretical modeling have been reviewed in the pages of Reviews of Modern Physics (Brabec and Krausz, 2000). Since then, measurement and control of the subcycle field evolution of few-cycle light have opened the door to a radically new approach to exploring and controlling processes of the microcosm. The hyperfast-varying electric field of visible light permitted manipulation and tracking of the atomic-scale motion of electrons. Striking implications include controlled generation and measurement of single attosecond pulses of extreme ultraviolet light as well as trains of them, and real-time observation of atomic-scale electron dynamics. The tools and techniques for steering and tracing electronic motion in atoms, molecules, and nanostructures are now becoming available, marking the birth of attosecond physics. In this article these advances are reviewed and some of the expected implications are addressed.
Session details: Course 3: Sketch-based interfaces: techniques and applications (2007)

No abstract available.
Growth has Independence feeling better (2016)

It is universally accepted in the industry that it is better to build mines at the bottom of the cycle when contractors, materials and labour are all cheaper. Independence Group Ltd managing director Peter Bradford agrees with the assertion but believes the opportunity afforded his company isn't one of cost savings, but improved growth prospects.
Increased Systemic Exposure of Fimasartan, an Angiotensin II Receptor Antagonist, by Ketoconazole and Rifampicin (2012)

The authors studied the effects of ketoconazole and rifampicin on the pharmacokinetics of a single dose of fimasartan (BR-A-657), a newly developed angiotensin II receptor antagonist for the treatment of hypertension, in 22 healthy participants. Ketoconazole increased the maximumplasma concentration (Cmax) and area under the plasma concentration vs time curve to infinity (AUC∞ of fimasartan by 2.47-fold (90% confidence interval [CI], 1.61-3.79) and 2.03-fold (1.56-2.64), respectively. Concomitant administration of rifampicin increased the C(max) and AUC∞ of fimasartan by 10.33-fold (90% CI, 6.74-15.81) and 4.60-fold (3.54-5.97). In vitro studies indicated that ketoconazole inhibited the uptake of fimasartan into cells expressing OATP1B1 with a K(i) of 107.7 µM, and rifampicin inhibited OAT1- and OATP1B1-mediated fimasartan transport with a K(i) of 212 µM and 12.2 µM, respectively. The systemic exposure of fimasartan was significantly increased by coadministration of ketoconazole or rifampicin in healthy volunteers. This is consistent with the in vitro results, in which fimasartan is a substrate of CYP3A and OATP1B1.
Development of a Subsurface Reverse Circulation Tool System to Cement Weak and Depleted Zones in Deepwater Formations (2016)

Abstract Reverse circulation cementing is a placement technique that reduces bottomhole equivalent circulating densities (ECDs) and reduces lost circulation risk in wells in which conventional circulation pressures would break down formations. Until now, reverse circulation cementing has been performed only on land or in shallow-water wells in which the annulus was accessible from the surface to pump down. This paper describes the design, development, and validation of technology that enables subsurface reverse circulation. Gaps in technology have made it challenging to transfer reverse-cementing-placement techniques to primary cementing operations in deepwater. To reverse cement a liner, fluids must be pumped down the work string to prevent potential contact inside the riser and blowout preventer (BOP), and then fluids must be injected into the annulus downhole while full circulation continues. A tool system was developed to facilitate this unique flow path, provide alternative methods to set liner hangers, and provide flexibility for contingencies and other operational requirements. The developed subsurface reverse circulation tool system uses radio frequency identification (RFID) technology so that the tools can be operated remotely and repeatedly either by RFID tags or through surface-pressure pulse sequences. Three RFID-activated tools were designed: a circulation tool, a crossover tool, and a downhole flapper. The prototype tool system was first evaluated through bench testing of individual components and then through large-scale rig testing. During the rig trials, the entire system was run into a test well, and a multiday sequence of flow testing validated the function and performance of each tool. After successful testing in rig trials, the subsurface reverse circulation tools (RCT) were deployed in the Appalachia basin field, located in the Northeastern United States. This paper discusses the requirements of a subsurface reverse-circulation-cementing system. It describes the design, development, and validation of technology that enables subsurface reverse circulation. It also describes the prototype system that was built and the field testing results. This new capability enables the cement to be pumped down the work string and then to exit to the annulus at a point above the liner string.
Sichere Fehlerdiagnose in der Automobilwartung mit RODON 3 (2004)

Der wachsende Anteil integrierter Kommunikationsnetzwerke im Fahrzeug legt zum einen die Basis fuer neue Konzepte in Sachen Fahrsicherheit und Fahrdynamik sowie internetbasierter Kommunikationsdienste. Zum anderen ist dieser hohe Technologisierungsgrad auch die Grundlage fuer elektronische Pannen und Systemausfaelle, die selbst durch versierte Systemtechniker teilweise nur schwer zu beheben sind. Abhilfe koennen hier Diagnosesysteme schaffen, die durch umfangreiches Diagnosewissen ueber das System und intelligente Diagnosestrategien den Fehler in den Fehlerketten zuegig und eindeutig lokalisieren. Vorgestellt wird mit R.O.S.E. ein Software-Werkzeug, das eine durchgaengige Diagnoseloesung darstellt und von der Entwicklung bis zu Diagnosemodulen im Fahrzeug oder in der Werkstatt reicht. Fuer unterschiedliche Phasen des Produktlebenszyklus vom fruehen Systementwurf bis zum Einsatz in der Werkstatt sind damit Verfahren und Werkzeuge verfuegbar, die eine effiziente und wirkungvolle Unterstuetzung fuer die Diagnosentwicklung darstellen.
The American Soldier: An Assessment, Several Wars Later (1989)

THE AMERICAN SOLDIER: AN ASSESSMENT, SEVERAL WARS LATER Get access ROBIN M. WILLIAMS, JR. ROBIN M. WILLIAMS, JR. Henry Scarborough Professor of Social Science, Emeritus, at Cornell University Search for other works by this author on: Oxford Academic Google Scholar Public Opinion Quarterly, Volume 53, Issue 2, Summer 1989, Pages 155–174, https://doi.org/10.1086/269501 Published: 01 January 1989
Galectin‐3 regulates the adhesive interaction between breast carcinoma cells and elastin (1999)

Galectin-3 is a beta-galactoside binding lectin whose precise physiological role is not yet defined. In the present studies, we questioned whether galectin-3 plays a role in the adhesion of breast carcinoma cells to elastin. The impetus for this analysis was the initial observation that the cellular receptor for elastin, the 67 kDa elastin/laminin protein may have galectin-like properties (Mecham et al. [1989] J. Biol. Chem. 264:16652–16657). We therefore analyzed the adhesion of breast carcinoma cells to microtiter wells coated with elastin under conditions which eliminate integrin participation in adhesion. The adhesion assay was done in the absence and presence of purified recombinant galectin-3. We hereby demonstrate that high concentrations of galectin-3 ligate breast carcinoma cells to microtiter wells coated with elastin. Galectin-3 also demonstrated a specific binding interaction with purified elastin in a dose and lactose dependent manner. Furthermore we demonstrated by immunoprecipitation that endogenous galectin-3 in breast carcinoma cells is associated with tropoelastin. Lastly, the breast carcinoma cells which expressed galectin-3 on their surface, demonstrated enhanced cellular proliferation on elastin compared to galectin-3 null expressing cells. These studies suggest that galectin-3 is capable of regulating the interactions between cells and elastin. J. Cell. Biochem. 75:505–514, 1999. © 1999 Wiley-Liss, Inc.
<title>E-beam lithography: a suitable technology for fabrication of high-accuracy 2D and 3D surface profiles</title> (1995)

The fabrication of surface profiles may become an interesting technology in the field of micromachining. Recently, surface profiles are known and widely used in optics, especially in diffractive optics. E-beam lithography is a suitable technology for the fabrication of such profiles. This paper gives an overview about the experiences and results achieved at the Friedrich-Schiller-University Jena, Germany, on this field for some years. At first we describe the challenges and obstacles of typical optical profiles with regard to e-beam writing technology. After introducing our two different e-beam writers ZBA 23H (variable shaped beam) and LION LV1 (high resolution gaussian beam) we demonstrate different writing strategies for the fabrication of binary, multilevel and continuous surface profiles. Variable energy writing is a new technology extending the abilities of the well-known variable dose writing. Some selected examples of interesting patterns and profiles, as holograms, gear wheels, lenses, gratings and encoder discs, demonstrate different aspects to be considered and the possible solutions for some problems.
Correlation of striatal fluorodopa uptake in the MPTP Monkey with dopaminergic indices (1993)

Striatal 18F-6-fluorodopa (FD) uptake constants were measured by positron emission tomography in (1) normal cynomolgus monkeys and (2) a series of cynomolgus and rhesus monkeys that had received intracarotid infusions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). After the animals were killed, the number and average size of dopaminergic neurons in the substantia nigra pars compacta were measured. Striatal levels of dopamine and its metabolites, and the striatal activities of the dopaminergic synthetic enzymes, were also determined. The striatal FD uptake constants showed highly significant positive correlations with both number and size of dopaminergic neurons, indicating atrophy of surviving neurons in MPTP-treated animals. The uptake constants also showed significant positive correlations with striatal levels of dopamine, total catecholamines, and the activities of the synthetic enzymes. Both histochemical and biochemical data on tyrosine hydroxylase suggested some contralateral enzyme loss in these MPTP-treated monkeys, as well as decreased enzyme activity in surviving neurons on the lesioned side. However, residual enzyme activities were apparently not rate limiting to striatal FD uptake. It is concluded that PET-FD measurements by positron emission tomography provide a good index of the integrity of the nigrostriatal pathway.
Syntheses and aggregation properties of new water-soluble calixarenes (1989)

Eighteen water-soluble calixarenes have been synthesized and their aggregation properties in water studied. They are six anionic calixarenes (1n) having sulphonate groups on the upper rim, nine anionic calixarenes (2n) having sulphonate groups on the lower rim, and three cationic calixarenes (3n) having ammonium groups on the upper rim. On the basis of measurements of critical micelle concentrations (c.m.c.s.) by surface tension, conductance, and spectroscopic methods, it was concluded that the aggregation behaviour of these water-soluble calixarenes can be classified into three categories: (i) non-micellar calixarenes, (ii) micelle-forming calixarenes, and (iii) unimolecular micellar calixarenes. The possible structure-aggregation relationships are discussed.
Genomic imprinting of <i>Xist</i> by maternal H3K27me3 (2017)

Maternal imprinting at the <i>Xist</i> gene is essential to achieve paternal allele-specific imprinted X-chromosome inactivation (XCI) in female mammals. However, the mechanism underlying <i>Xist</i> imprinting is unclear. Here we show that the <i>Xist</i> locus is coated with a broad H3K27me3 domain that is established during oocyte growth and persists through preimplantation development in mice. Loss of maternal H3K27me3 induces maternal <i>Xist</i> expression and maternal XCI in preimplantation embryos. Our study thus identifies maternal H3K27me3 as the imprinting mark of <i>Xist</i>.
Evaluation of Genotypic and Phenotypic Methods To Distinguish Clinical from Environmental <i>Vibrio vulnificus</i> Strains (2009)

Vibrio vulnificus is a heterogeneous bacterial species that comprises virulent and avirulent strains from environmental and clinical sources that have been grouped into three biotypes. To validate the typing methods proposed to distinguish clinical from environmental isolates, we performed phenotypic (API 20E, API 20NE, and BIOLOG tests) and genetic (ribotyping and DNA polymorphism at several loci) studies with a large strain collection representing different biotypes, origins, and host ranges. No phenotypic method was useful for biotyping or grouping strains with regard to the origin of an isolate, and only the BIOLOG system was reliable for identifying the strains at the species level. DNA polymorphisms divided the population into three major profiles. Profile 1 strains were vcg type C, 16S rRNA type B, and vvh type 1 and included most of the biotype 1 human septicemic isolates; profile 2 strains were vcg type E, 16S rRNA type A, and vvh type 2 and included all biotype 2 isolates together with biotype 1 isolates from fish and water and some human isolates; and profile 3 strains were vcg type E, 16S rRNA type AB, and vvh type 2 and included biotype 3 strains. Ribotyping divided the species into two groups: one group that included profile 1 biotype 1 isolates and one group that included isolates of all three biotypes with the three profiles described above. In conclusion, no genotyping system was able to distinguish either clinical strains from environmental strains or biogroups within the species V. vulnificus, which suggests that new typing methodologies useful for public health have to be developed for this species.
Filtered Backprojection Algorithms for Spiral Cone Beam CT (2004)

In this paper we review two algorithms proposed recently by one of the authors, for the inversion of spiral cone beam data. The algorithms have a filtered backprojection structure, and the filtering step is shift invariant. Both algorithms are based on the PI line idea and solve the long object problem. One of the algorithms is approximate, and the other one is theoretically exact. We discuss various theoretical properties of the algorithms, and illustrate their performance by the results of numerical experiments.
Enhanced photocatalytic activity of quantum-confined tungsten trioxide nanoparticles in mesoporous silica (2010)

Due to quantum confinement effects, tungsten trioxide nanoparticles approximately 1.4 nm in diameter prepared in channels of mesoporous silica exhibited a widened bandgap and enhanced photocatalytic performance in the decomposition of benzene.
GPRS: General Packet Radio Service (2001)

From the Publisher:
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* The complete layout of GPRS system architecture 
* The function of GPRS elements 
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Automated retinal analysis (2006)

Diabetes is a chronic disease affecting over 2% of the population in the UK [1]. Long-term complications of diabetes can affect many different systems of the body including the retina of the eye. In the retina, diabetes can lead to a disease called diabetic retinopathy, one of the leading causes of blindness in the working population of industrialised countries. The risk of visual loss from diabetic retinopathy can be reduced if treatment is given at the onset of sight-threatening retinopathy. To detect early indicators of the disease, the UK National Screening Committee have recommended that diabetic patients should receive annual screening by digital colour fundal photography [2]. Manually grading retinal images is a subjective and costly process requiring highly skilled staff. This thesis describes an automated diagnostic system based oil image processing and neural network techniques, which analyses digital fundus images so that early signs of sight threatening retinopathy can be identified. Within retinal analysis this research has concentrated on the development of four algorithms: optic nerve head segmentation, lesion segmentation, image quality assessment and vessel width measurements. This research amalgamated these four algorithms with two existing techniques to form an integrated diagnostic system. The diagnostic system when used as a 'pre-filtering' tool successfully reduced the number of images requiring human grading by 74.3%: this was achieved by identifying and excluding images without sight threatening maculopathy from manual screening.