gebhart/patrepeval huggingface dataset:
Transmitting and decoding facial expressions of emotion during healthy aging: More similarities than differences (2018)

Older adults tend to perform more poorly than younger adults on emotional expression identification tasks. The goal of the present study was to test a processing mechanism that might explain these differences in emotion recognition-specifically, age-related variation in the utilization of specific visual cues. Seventeen younger and 17 older adults completed a reverse-correlation emotion categorization task (Bubbles paradigm), consisting of a large number of trials in each of which only part of the visual information used to convey an emotional facial expression was revealed to participants. The task allowed us to pinpoint the visual features each group used systematically to correctly recognize the emotional expressions shown. To address the possibility that faces of different age groups are differently processed by younger and older adults, we included younger, middle-aged, and older adult face models displaying happy, fearful, angry, disgusted, and sad facial expressions. Our results reveal strong similarity in the utilization of visual information by younger and older adult participants in decoding the emotional expressions from faces across ages-particularly for happy and fear emotions. These findings suggest that age-related differences in strategic information use are unlikely to contribute to the decline of facial expression recognition skills observed in later life.
Segregation algorithm: splitting the training set improves learning (1989)

Summary form only given. A learning algorithm for feedforward backpropagation networks is proposed that improves the net's ability to generalize or to learn the training set compared to standard backpropagation, using an equal number of learning steps. Thus the algorithm needs fewer learning steps to obtain the same percentage of correct responses in the training set. The proposed algorithm makes an estimate of the required number of units and increases it when necessary. It takes into account the distribution of patterns among classes and adapts its topology accordingly. Execution time is significantly reduced as fewer weight updates per learning iteration are required.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The Downregulation of MiR-182 Is Associated with the Growth and Invasion of Osteosarcoma Cells through the Regulation of TIAM1 Expression (2015)

Down-expression of miR-182 in osteosarcoma promoted tumor growth, migration and invasion by targeting TIAM1. MiR-182 might act as a tumor suppressor gene whose down-regulation contributes to the progression and metastasis of osteosarcoma, providing a potential therapy target for osteosarcoma patients.
Near-field and far-field patterns of phase-locked semiconductor laser arrays (1983)

A gain-guided phase-locked semiconductor laser array has been observed to emit a single narrow lobed far-field radiation pattern up to 70 mW, at which power level it exhibits a distinct change. We show that this effect results from a new phase-locked mode attaining threshold; the original mode remains phase locked above this power level.
An interaction between DNA ligase I and proliferating cell nuclear antigen: Implications for Okazaki fragment synthesis and joining (1997)

Although three human genes encoding DNA ligases have been isolated, the molecular mechanisms by which these gene products specifically participate in different DNA transactions are not well understood. In this study, fractionation of a HeLa nuclear extract by DNA ligase I affinity chromatography resulted in the specific retention of a replication protein, proliferating cell nuclear antigen (PCNA), by the affinity resin. Subsequent experiments demonstrated that DNA ligase I and PCNA interact directly via the amino-terminal 118 aa of DNA ligase I, the same region of DNA ligase I that is required for localization of this enzyme at replication foci during S phase. PCNA, which forms a sliding clamp around duplex DNA, interacts with DNA pol delta and enables this enzyme to synthesize DNA processively. An interaction between DNA ligase I and PCNA that is topologically linked to DNA was detected. However, DNA ligase I inhibited PCNA-dependent DNA synthesis by DNA pol delta. These observations suggest that a ternary complex of DNA ligase I, PCNA and DNA pol delta does not form on a gapped DNA template. Consistent with this idea, the cell cycle inhibitor p21, which also interacts with PCNA and inhibits processive DNA synthesis by DNA pol delta, disrupts the DNA ligase I-PCNA complex. Thus, we propose that after Okazaki fragment DNA synthesis is completed by a PCNA-DNA pol delta complex, DNA pol delta is released, allowing DNA ligase I to bind to PCNA at the nick between adjacent Okazaki fragments and catalyze phosphodiester bond formation.
A Frequency Dependent Ray Theory (1988)

Abstract : Practical computational procedures for obtaining ray theoretical solutions to the inhomogeneous Helmholtz equation resort to a well known approximation. The computational method presented here enables one to trace rays without resort to the ray theory approximation provided a solution to the Helmholtz equation is available by independent means. In other words, given a solution to the Helmholtz equation, the exact rays for that case can be computed. The new ray theory therefore serves, not as computational method, but as a new method of displaying solutions to the Helmholtz equation. Keywords: Ray theory; Acoustic propagation.
Heat shock stimulates the release of arachidonic acid and the synthesis of prostaglandins and leukotriene B<sub>4</sub> in mammalian cells (1989)

Heat shock has a profound influence on the metabolism and behavior of eukaryotic cells. We have examined the effects of heat shock on the release from cells of arachidonic acid and its bioactive eicosanoid metabolites, the prostaglandins and leukotrienes. Heat shock (42-45 degrees) increased the rate of arachidonic acid release from human, rat, murine, and hamster cells. Arachidonate accumulation appeared to be due, at least partially, to stimulation of a phospholipase A2 activity by heat shock and was accompanied by the accumulation of lysophosphatidyl-inositol and lysophosphatidylcholine in membranes. Induction of arachidonate release by heat did not appear to be mediated by an increase in cell Ca++. Stimulation of arachidonate release by heat shock in hamster fibroblasts was quantitatively similar to the receptor-mediated effects of alpha thrombin and bradykinin. The effects of heat shock and alpha thrombin on arachidonate release were inhibited by glucocorticoids. Increased arachidonate release in heat-shocked cells was accompanied by the accelerated accumulation of cyclooxygenase products prostaglandin E2 and prostaglandin F2 alpha and by 5-lipoxygenase metabolite leukotriene B4. Elevated concentrations of arachidonic acid and metabolites may be involved in the cytotoxic effects of hyperthermia, in homeostatic responses to heat shock, and in vascular and inflammatory reactions to stress.
Template matching based object recognition with unknown geometric parameters (2002)

In this paper, we examine the problem of locating an object in an image when size and rotation are unknown. Previous work has shown that with known geometric parameters, an image restoration method can be useful by estimating a delta function at the object location. When the geometric parameters are unknown, this method becomes impractical because the likelihood surface to be minimized across size and rotation has numerous local minima and areas of zero gradient. We propose a new approach where a smooth approximation of the template is used to minimize a well-behaved likelihood surface. A coarse-to-fine approximation of the original template using a diffusion-like equation is used to create a library of templates. Using this library, we can successively perform minimizations which are locally well-behaved. As detail is added to the template, the likelihood surface gains local minima, but previous estimates place us within a well-behaved "bowl" around the global minimum, leading to an accurate estimate. Numerical experiments are shown which verify the value of this approach for a wide range of values of the geometric parameters.
On The Security of The ElGamal Encryption Scheme and Damgard's Variant. (2008)

Abstract. In this paper, we give security proofs for ElGamal encryption scheme and its variant by Damg˚ard (DEG). For the ElGamal encryption, we show that (1) under the delayed-target discrete log assumption and a variant of the generalized knowledge-of-exponent assumption, ElGamal encryption is one-way under non-adaptive chosen cipher attacks; (2) one-wayness of ElGamal encryption under non-adaptive chosen cipher attacks is equivalent to the hardness of the delayed-target computational Diffie-Hellman problem. For DEG, (1) we give a new proof that DEG is semantically secure against non-adaptive chosen ciphertext attacks under the delayed-target decisional Diffie-Hellman assumption (although the same result has been presented in the literature before, our proof seems simpler); (2) we show that the DHK1 assumption, which was first proposed for DEG security proof, is stronger than necessary. A decisional (thus weaker) version of DHK1 assumption is sufficient for DEG security proof. Keywords: ElGamal encryption, Damg˚ard’s ElGamal, security proof. 1
Identification of Sites in the Second Exomembrane Loop and Ninth Transmembrane Helix of the Mammalian Na+/H+ Exchanger Important for Drug Recognition and Cation Translocation (2001)

Mammalian Na(+)/H(+) exchanger (NHE) isoforms are differentially sensitive to inhibition by several distinct classes of pharmacological agents, including amiloride- and benzoyl guanidinium-based derivatives. The determinants of drug sensitivity, however, are only partially understood. Earlier studies of the drug-sensitive NHE1 isoform have shown that residues within the fourth membrane-spanning helix (M4) (Phe(165), Phe(166), Leu(167), and Gly(178)) and a 66-amino acid segment encompassing M9 contribute significantly to drug recognition. In this report, we have identified two residues within M9, one highly conserved (Glu(350)) and the other non-conserved (Gly(356)), that are major determinants of drug sensitivity. In addition, residues in the second exomembrane loop between M3 and M4 (Gly(152), Phe(157), and Pro(158)) were also found to modestly influence drug sensitivity. A double substitution of crucial sites within M4 and M9 of NHE1 with the corresponding residues present in the drug-resistant NHE3 isoform (i.e. L167F/G356A) greatly reduced drug sensitivity in a cooperative manner to levels nearing that of wild type NHE3. The above mutations did not appreciably affect Na(o)(+) affinity but did markedly decrease the catalytic turnover of the transporter. These data suggest that specific sites encompassing M4 and M9 are critical determinants of both drug recognition and cation translocation.
Neurosteroid Effects on GABAergic Synaptic Plasticity in Hippocampus (2003)

We have previously reported that short-term (48-72 h) exposure to the GABA-modulatory steroid 3alpha-OH-5alpha-pregnan-20-one (3alpha,5alpha-THP) increases expression of the alpha4 subunit of the GABA(A) receptor (GABAR) in the hippocampus of adult rats. This change in subunit composition was accompanied by altered pharmacology and an increase in general excitability associated with acceleration of the decay time constant (tau) for GABA-gated current of pyramidal cells acutely isolated from CA1 hippocampus similar to what we have reported following withdrawal from the steroid after chronic long-term administration. Because GABAR can be localized to either synaptic or extrasynaptic sites, we tested the hypothesis that this change in receptor kinetics is mediated by synaptic GABAR. To this end, we evaluated the decay kinetics of TTX-resistant miniature inhibitory postsynaptic currents (mIPSCs) recorded from CA1 pyramidal cells in hippocampal slices following 48-h treatment with 3alpha,5alpha/beta-THP (10 mg/kg, ip). Hormone treatment produced a marked acceleration in the fast decay time constant (tau(fast)) of GABAergic mIPSCs. This effect was prevented by suppression of alpha4-subunit expression with antisense (AS) oligonucleotide, suggesting that hormone treatment increases alpha4-containing GABAR subsynaptically. This conclusion was further supported by pharmacological data from 3alpha,5beta-THP-treated animals, demonstrating a bimodal distribution of taus for individual mIPSCs following bath application of the alpha4-selective benzodiazepine RO15-4513, with a shift to slower values. Because 40-50% of the individual taus were also shifted to slower values following bath application of the non-alpha4-selective benzodiazepine agonist lorazepam (LZM), we suggest that the number of GABAR synapses containing alpha4 subunits is equivalent to those that do not following 48-h administration of 3alpha,5beta-THP. The decrease in GABAR-mediated charge transfer resulting from accelerated current decay may then result in increased excitability of the hippocampal circuitry, an effect consistent with the increased behavioral excitability we have previously demonstrated.
Of Petsval, Pitch, and Profit (1977)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text RICHARD F. WEEKS, "Of Petsval, Pitch, and Profit," Optics News 3(4), 5-6 (1977) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Ecological and Genetic Effects of Salmonid Introductions in North America (1991)

Stocking of non-native Salmoninae into North American waters began around 1870. Brown trout (Salmo trutta) from Europe established populations across North America and is the only successful inter-continental introduction. Introductions of native salmonids within North America but outside their native ranges have been common. Ecological effects of salmonid introductions. include competition, predation on native salmonids and other fishes, environmental modification through digging of redds in stream bottom substrates during spawning, and introduction of parasites and disease to native fish. Direct genetic effects from stocked salmonids are caused by interbreeding with native species. Indirect genetic effects may result through selective forces and/or a reduction of effective population size, genetic drift, and inbreeding. Management actions used to remove non-native salmonid populations include chemical reclamation and construction of barriers to movement. Salmonid stocking as a management practice is appropriate for species or population rehabilitation. Continued stocking of non-native salmonids should cease where viable native salmonid populations exist. New introductions of Eurasian species should not be made because effects are unpredictable. Aquaculture and the creation of transgenic fish pose special threats to North American salmonids. The era of widespread, intentional introductions of salmonids by man justifiably is drawing to a close.
Isosceles right triangular waveguides with boundary conditions of composite electric and magnetic walls (2015)

Isosceles right triangular waveguides with six kinds of boundary conditions of composite electric and magnetic walls are discussed in this paper. The completed closed-form modal solutions are derived for both transverse electric and transverse magnetic modes. These exact solutions not only serve as accuracy standards for approximate methods, but also solve a fundamental problem. Their corresponding electric field distributions are plotted for the dominant modes of the six kinds of isosceles right triangular waveguides. Finally, electric field distributions excited in the quarter-mode substrate integrated waveguide and eighth-mode substrate integrated waveguide are studied, and they are in good agreement with theoretical predictions.
"Flying-Adder" PLL Based Synchronization Mechanism for Data Packet Transport (2007)

A novel frequency synthesis architecture, Flying-Adder architecture, has been developed in recent years. Compared with conventional PLL based frequency synthesis techniques, this new method has many unique features. Among them, the two most distinguishing ones are its instantaneous response speed and very fine frequency resolution. These features can be especially beneficial to application of data smoothing in packet-oriented transport systems. In this paper, this Flying-Adder PLL based synchronization approach is demonstrated through two real examples.
Thasos : quelques problèmes de structure urbaine (1987)

Martin Roland. Thasos : quelques problèmes de structure urbaine. In: Architecture et urbanisme. Préface de Jean Pouilloux et Georges Vallet. Rome : École Française de Rome, 1987. pp. 449-465. (Publications de l'École française de Rome, 99)
Multiple metal-carbon bonds. 39. Preparation of molybdenum and tungsten neopentylidyne complexes of the type M(CCMe3)(O2CR)3, their reactions with acetylenes, and the x-ray structure of the .eta.3-cyclopropenyl complex W[C3(CMe3)Et2](O2CCH3)3 (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMultiple metal-carbon bonds. 39. Preparation of molybdenum and tungsten neopentylidyne complexes of the type M(CCMe3)(O2CR)3, their reactions with acetylenes, and the x-ray structure of the .eta.3-cyclopropenyl complex W[C3(CMe3)Et2](O2CCH3)3Richard R. Schrock, John S. Murdzek, John H. Freudenberger, Melvyn Rowen Churchill, and Josephh W. ZillerCite this: Organometallics 1986, 5, 1, 25–33Publication Date (Print):January 1, 1986Publication History Published online1 May 2002Published inissue 1 January 1986https://pubs.acs.org/doi/10.1021/om00132a005https://doi.org/10.1021/om00132a005research-articleACS PublicationsRequest reuse permissionsArticle Views293Altmetric-Citations32LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Growth of Aeromonas spp. on cefsulodin-Irgasan-novobiocin agar selective for Yersinia enterocolitica (1985)

Twenty-eight strains of Aeromonas spp. were analyzed for their ability to grow on two different kinds of cefsulodin-Irgasan (triclosan; Ciba-Geigy AG, Basel, Switzerland)-novobiocin (CIN) agar containing 15 or 4 mg of cefsulodin per ml and on inositol-bile salts-brilliant green (IBB) agar. Relative to blood agar, 68% of the strains were inhibited by more than 2 logs (i.e., less than 1% growth) at 37 degrees C (39% at 25 degrees C) on CIN I (high cefsulodin concentration), 7% were inhibited at either temperature on CIN II (low cefsulodin concentration), 4% were inhibited on IBB agar at 37 degrees C, and none were inhibited on IBB agar at 25 degrees C. These results reflect the MICs of cefsulodin on CIN Base: the MIC for 50% of the strains was 8 mg/liter at 37 and 25 degrees C, and the MICs for 90% of the strains were 16 mg/liter at 37 degrees C and 64 mg/liter at 25 degrees C. The MICs of Irgasan and novobiocin were far beyond the concentrations used in CIN media. We argue that CIN agar containing 4 mg of cefsulodin per ml (CIN II) can be used for the simultaneous detection of Aeromonas spp. and Yersinia spp.
In vitro mode of action, pharmacokinetics, and organ specificity of poly (maleic acid-styrene)-conjugated neocarzinostatin, SMANCS. (1982)

The organ specificity and pharmacokinetics of SMANCS, poly (maleic acid-styrene)-conjugated neocarzinostatin (NCS), were investigated in rats. The drug activity accumulated primarily in the regional lymph nodes after subcutaneous injection. After intravenous injection, the drug was found in the kidney, lymph nodes, and bladder in very high concentrations, and in lesser concentrations in the bone marrow, lung, small intestine, liver and spleen. The urinary excretion rate and total recovery of the drug after intravenous injection were higher than those after subcutaneous injection. SMANCS, having a molecular weight of 2.5 x 10(4) daltons, was degraded in vivo to NCS (mol. wt. about 1.1 x 10(4)). This was also confirmed in vitro by incubating the drug with cell homogenates. SMANCS caused strand scission of DNA similarly to NCS in lymphoblastoid cells. However, in a cell-free system using colicin E1 plasmid DNA, a high concentration of SMANCS was required to produce DNA degradation detectable by the alkaline sucrose gradient method.
Against the Gods: The Remarkable Story of Risk (1996)

People constantly make choices, arrive at decisions, and take risks. Savers buy stocks, doctors perform operations, poker players figure the odds, and business managers launch new products. Without the instruments of risk management, such decisions would be impossible, because no one could figure out the likelihood of success. Yet the idea that we need not listen to soothsayers for advice is less than five hundred years old. This book blends biography with history and science to show how famous thinkers like Pascal, Bernoulli, Bayes, Keynes, Markowitz, Arrow and von Neumann paved the way from superstition to the supercomputer. But Bernstein tells of others as well, less known but equally important in developing the theory and practice of risk management. The book also explains significant concepts including probability, uncertainty, the distinction between chance and skill, the interactions between gambling and investing, and rational versus irrational decision-making.--From publisher description.
Perfctr-Xen (2011)

Virtualization is a powerful technique used for variety of application domains, including emerging cloud environments that provide access to virtual machines as a service. Because of the interaction of virtual machines with multiple underlying software and hardware layers, the analysis of the performance of applications running in virtualized environments has been difficult. Moreover, performance analysis tools commonly used in native environments were not available in virtualized environments, a gap which our work closes.
A Microwave Frequency Halver with Conversion Gain (1986)

A novel frequency halver circuit is presented, based on the concept of parametric division using a Schottky diode. This technique utilizes the gate to source Schottky diodes of two FETs in a half frequency, resonant loop configuration. Measurements of such a frequency divider, for an input signal in X-band, show conversion gain with good suppression of the fundamental frequency. Unlike its predecessors, it is characterized by a low turn-on threshold.