gebhart/patrepeval huggingface dataset:
Comparison of Enzyme-Linked Immunosorbent Assays with Chemiluminescent and Colorimetric Detection for the Determination of Ochratoxin A in Food (2011)

A direct competitive chemiluminescent enzyme-linked immunosorbent assay (CL-ELISA) for the determination of ochratoxin A (OTA) was developed using soybean peroxidase (SbP) in combination with 3-(10'-phenothiazinyl)propane-1-sulfonate (SPTZ) and 4-morpholinopyridine (MORPH) as a detection system. By varying the concentrations of the capture monoclonal anti-OTA antibody, a conjugate of OTA with SbP, and the composition of blocking buffers, the conditions of the immunoassay were optimized. Advantages of CL-ELISA were demonstrated by comparison with ELISA with colorimetric detection (COL-ELISA). The values of IC₁₀, IC₅₀, and working range (IC₂₀-IC₈₀) for CL-ELISA and COL-ELISA were 0.01, 0.08, and 0.02-0.3 ng/mL and 0.08, 0.58, and 0.17-2.2 ng/mL, respectively. The recovery values of CL-ELISA from three soybean spiked samples with OTA concentrations of 0.07, 0.1, and 0.15 ng/mL ranged from 72 to 125%. Determination of OTA in 21 various agricultural commodities showed that OTA in 8 examined samples was not detected by COL-ELISA. Furthermore, it was found that in 4 of these 8 samples the developed CL-ELISA determined OTA at levels from 0.96 to 4.64 ng/g.
Electro-Optical Performance of a Zero Pre-Tilt Liquid Crystal Cell Fabricated by Using the Field-Induced UV-Alignment Method (2015)

The liquid crystal alignment method using a UV-curable polymer has been reported for the zero pre-tilt angle of liquid crystals (see the paper by Oh in Optics Express, vol. 23, p. 1044, 2015). In this paper, we report the electro-optical characteristics and parameters related to the image quality of a fringe-field switching cell fabricated using the field-induced UV-alignment method as functions of the monomer concentration and the UV irradiation time. The results show that the field-induced UV-alignment method has a high potential for practical display applications.
Mini symposium: analysis of therapies for anovulation and miscarriage. Critical analysis of intravenous immunoglobulin therapy for recurrent miscarriage (1999)

Critical analysis of intravenous immunoglobulin therapy for recurrent miscarriage An alloimmune abnormality is believed to be the cause of recurrent miscarriage in couples in whom no other cause can be identified. Because of its immunosuppressive properties, intravenous immunoglobulin (IVIG) is used as a treatment for this disorder. The purpose of this study was to determine whether IVIG improves the chance of successful pregnancy in women with recurrent miscarriage by using individual patient data from efficacy trials. Detailed information on each patient enrolled in these trials was obtained to evaluate the efficacy of IVIG and investigate the effect of clinical variability on pregnancy outcome. Data from 125 patients in the IVIG group and 115 patients in the placebo group were available for analysis. Although the number of previous miscarriages and female age were both negative prognostic factors for successful outcome, there was no significant improvement in successful pregnancy or live birth rate with IVIG. Subgroup analyses indicated that timing of IVIG administration may be important. The results of the present study highlight the importance of stratification for known confounders, so that the role of IVIG can be evaluated in more detail. The collective evidence thus far indicates that IVIG does not have a therapeutic effect that is clinically meaningful.
A Spatial Methodology for the estimation of housing price in Albacete (1999)

The aim of this paper is to analyse the spatial behaviour of the free housing price in Albacete. We decided to write it because of the socieconomic importance of the housing subsector in the local, regional and national economy and its implications for Housing Policy. To achieve this aim, we have used the models and estimators imported from Geology, called kriging. In the geostatistics bibliography, the theoretical methodology is precise, since it estimates a spatial process in a point or region in space as a linear combination of a part of the spatial observations or all of them. In order to do this, it is neccesary to know the structure of spatial dependence of the process which is shown in the variogram and, assuming that the process verifies second order or intrinsic stationarity, then the ordinary or the universal kriging estimator can be calculated respectively. Before applying this procedure to study the housing price in Albacete, the factors which settle their price are analysed (size, age, quality and with or without garage). By deleting such effects and by reducing all the observations to a class of equivalent housing, four methods of modelization and estimation are used: universal kriging and ordinary kriging on the residuals of a generalized additive model for the point estimation, and universal kriging and median polish kriging for the block estimation. We select the last one as the best one to model the spatial behaviour of the housing price in Albacete.
Generalization of the backpropagation neural network learning algorithm to permit complex weights (1990)

The backpropagation neural network learning algorithm is generalized to include complex-valued interconnections for possible optical implementations.
Role of platelet membrane glycoproteins Ib/IX and IIb/IIIa, and of platelet alpha-granule proteins in platelet aggregation induced by human osteosarcoma cells. (1993)

We have previously shown that the platelet-aggregating activity of human MG-63 and HOS osteosarcoma cells depends at least in part upon tumor cell surface-associated thrombospondin, and suggested that platelet-osteosarcoma cell interactions could occur through interactions with specific platelet membrane receptors. In this study, the platelet-aggregating activity of MG-63 and HOS cells was studied by using a variety of platelet disorders. Both osteosarcoma cell lines induced a biphasic platelet aggregation response when added to normal platelet-rich plasma, while the second phase of aggregation was absent when added to gray platelets (deficiency in alpha-granule proteins) and to aspirin-treated platelets. Platelets from two unrelated patients with type I Glanzmann's thrombasthenia (deficiency in glycoprotein (GP) GPIIb/IIIa) did not aggregate at all with osteosarcoma cells. Using giant platelets from three patients with Bernard-Soulier syndrome (deficiency in GPIb/IX), the aggregation response induced by MG-63 and HOS cells was monophasic and reversible when compared to normal-sized platelets and to giant platelets from a patient with May-Hegglin anomaly (no membrane GP defect). Because GPIb serves as a receptor for von Willebrand factor during hemostasis, aggregation experiments were also conducted with the platelet-rich plasma of two patients with a low plasma von Willebrand factor concentration (type I von Willebrand's disease) before and after the infusion of deamino-D-arginine vasopressin. MG-63 and HOS cells induced biphasic platelet aggregation both before and after deamino-D-arginine vasopressin treatment, while the ristocetin-dependent binding of von Willebrand factor to platelets only occurred after deamino-D-arginine vasopressin treatment. Preincubation of normal platelet-rich plasma with monoclonal antibody SZ-2 directed against the von Willebrand binding domain of GPIb did not inhibit the platelet-aggregation activity of osteosarcoma cells, whereas anti-GPIb antibody SZ-2 did inhibit ristocetin-induced platelet agglutination. In addition, anti-GPIX antibodies did not affect platelet-osteosarcoma cell interactions. In conclusion, our data demonstrate that the first phase of the platelet-aggregating activity of human osteosarcoma cells is initiated by the interaction of these tumor cells with platelet membrane GPIIb/IIIa, whereas the second phase, even if plasma von Willebrand factor is deficient, involves platelet membrane GPIb and the participation of platelet alpha-granule proteins in membrane-mediated events, making aggregation irreversible.
Image Search Result Clustering and Re-Ranking via Partial Grouping (2007)

Image search result clustering has become an active research topic. However, due to the limitations of current image search engines, the search result always exhibits partial clustering character, which makes the traditional clustering assumption unreasonable. In this paper, we apply Bregman bubble clustering (BBC), which clusters only a fraction of the whole data set, to image search result clustering. We show that relevant and irrelevant images are less mixed in the clusters produced by BBC. Therefore, we are able to incorporate a cluster based relevance feedback scheme to the clustering result and improve the relevance ranking of the search result according to user's feedback. Experiments on animal images from Flickr demonstrate the effectiveness of our clustering and re-ranking algorithms.
The Effect of Some Substituents on the Thermal Breakdown of Diaryltetrazoles<sup>1</sup> (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Effect of Some Substituents on the Thermal Breakdown of Diaryltetrazoles1JOHN VAUGHAN and PETER A. S. SMITHCite this: J. Org. Chem. 1958, 23, 12, 1909–1912Publication Date (Print):December 1, 1958Publication History Published online1 May 2002Published inissue 1 December 1958https://pubs.acs.org/doi/10.1021/jo01106a023https://doi.org/10.1021/jo01106a023research-articleACS PublicationsRequest reuse permissionsArticle Views158Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Isolation of active recombinant XPG protein, a human DNA repair endonuclease. (1994)

Complementation group G of xeroderma pigmentosum (XP-G) is one of the most rare and phenotypically heterogeneous forms of this inherited disorder. XP-G patients vary from having a very mild defect in DNA repair to being severely affected, and a few cases are also associated with the neurological complications of Cockayne's syndrome. The XPG gene encodes an acidic protein with a predicted molecular mass of 133 kDa that confers normal UV resistance when expressed in XP-G cells. Here we report the isolation of full-length XPG as a soluble protein expressed from a recombinant baculovirus. The purified polypeptide corrects the DNA nucleotide excision repair defect of XP-G cell extracts in vitro, and it acts as a magnesium-dependent single-stranded DNA endonuclease. This is the first direct evidence for a human protein with properties that implicate it in the incision step of nucleotide excision repair.
Fair scheduling in wireless packet networks (1999)

Fair scheduling of delay and rate-sensitive packet flows over a wireless channel is not addressed effectively by most contemporary wireline fair-scheduling algorithms because of two unique characteristics of wireless media: (1) bursty channel errors and (2) location-dependent channel capacity and errors. Besides, in packet cellular networks, the base station typically performs the task of packet scheduling for both downlink and uplink flows in a cell; however, a base station has only a limited knowledge of the arrival processes of uplink flows. We propose a new model for wireless fair-scheduling based on an adaptation of fluid fair queueing (FFQ) to handle location-dependent error bursts. We describe an ideal wireless fair-scheduling algorithm which provides a packetized implementation of the fluid mode, while assuming full knowledge of the current channel conditions. For this algorithm, we derive the worst-case throughput and delay bounds. Finally, we describe a practical wireless scheduling algorithm which approximates the ideal algorithm. Through simulations, we show that the algorithm achieves the desirable properties identified in the wireless FFQ model.
Introduction (1991)

D’abord une image : celle du détective privé classique du roman noir. On ne peut l’imaginer que dans un décor urbain. Pas de campagne, de nature, de grand ciel ni de bosquets. Mais la rue, les bas-fonds, les bas quartiers, les hôtels louches, les ruelles solitaires, la nuit : la ville. Ce décor urbain est si insistant qu’il en devient obsédant. D’autant qu’il ne s’agit pas de n’importe quelle ville. On la voit sourde, sombre, crépusculaire, désolée. Ville de malheur et de violence, pleine d’o...
ChemInform Abstract: Highly Efficient, Thermally and Chemically Stable Nonlinear Optical Chromophores Based on the α‐Perfluoroaryldicyanovinyl Electron Acceptors. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Soziale Schichtung: Niedrige Einstufung der Ostdeutschen: Wahrnehmung und Bewertung Sozialer Ungleichheit im Ost-West-Vergleich (1992)

Im Mittelpunkt des Beitrags stehen verschiedene Aspekte der subjektiven Wahrnehmung und Bewertung der sozialen Ungleichheit. Es wird untersucht (1), welche Strukturen der sozialen Schichtung sich in Ost- und Westdeutschland auf der Basis der subjektiven Einstufung der Befragten ergeben, (2) ob und inwieweit die gegenwärtige Verteilung der Ressourcen und Lebenschancen von der Bevölkerung als gerecht beurteilt wird und (3) wie sich die Einstellungen gegenüber der sozialen Ungleichheit und deren Legitimation im Westen und Osten Deutschlands unterscheiden. Die empirischen Analysen basieren auf den Daten der Basisbefragung der Allgemeinen Bevölkerungsumfrage der Sozialwissenschaften (ALLBUS), die in den Monaten Mai bis Juli 1991 durchgeführt wurde und sich erstmals auch auf die neuen Bundesländer erstreckt.
Tissue Engineering of Heart Valves - Current Aspects (2002)

Tissue engineering of heart valves is an evolving research field. Driven by the shortcomings of the heart valve substitutes currently available, such as need for anticoagulation, susceptibility to infections, inability to grow and autorepair, the multidisciplinary approach for designing and growing viable heart valves identical to the native heart valves has begun. The following will give an update of the recent developments, current limitations and potential future applications of tissue-engineered heart valves.
A novel highly efficient broadband continuous class-F RFPA delivering 74% average efficiency for an octave bandwidth (2011)

A novel, highly efficient and broadband RF power amplifier (PA) operating in “continuous class-F” mode has been realized for first time. The introduction and experimental verification of this new PA mode demonstrates that it is possible to maintain expected output performance, both in terms of efficiency and power, over a very wide bandwidth. Using recently established continuous class-F theory, an output matching network was designed to terminate the first three harmonic impedances. This resulted in a PA delivering an average drain efficiency of 74% and average output power of 10.5 W for an octave bandwidth between 0.55 GHz and 1.1 GHz. A commercially available 10 W GaN HEMT transistor has been used for the PA design and realization.
Dynamic View Selection for Time-Varying Volumes (2006)

Animation is an effective way to show how time-varying phenomena evolve over time. A key issue of generating a good animation is to select ideal views through which the user can perceive the maximum amount of information from the time-varying dataset. In this paper, we first propose an improved view selection method for static data. The method measures the quality of a static view by analyzing the opacity, color and curvature distributions of the corresponding volume rendering images from the given view. Our view selection metric prefers an even opacity distribution with a larger projection area, a larger area of salient features' colors with an even distribution among the salient features, and more perceived curvatures. We use this static view selection method and a dynamic programming approach to select time-varying views. The time-varying view selection maximizes the information perceived from the time-varying dataset based on the constraints that the time-varying view should show smooth changes of direction and near-constant speed. We also introduce a method that allows the user to generate a smooth transition between any two views in a given time step, with the perceived information maximized as well. By combining the static and dynamic view selection methods, the users are able to generate a time-varying view that shows the maximum amount of information from a time-varying data set.
A Comparison of Rapid Bovine Spongiform Encephalopathy Testing Methods on Autolyzed Bovine Brain Tissue (2005)

In 1999, the European Union (EU) approved 3 rapid methods for the testing of bovine brain samples for the presence of bovine spongiform encephalopathy (BSE). The evaluation that led to the approval did not include an analysis of autolyzed material. Member states of the EU have active surveillance programs for BSE, which target fallen stock as well as other categories of cattle. Autolysis is a common feature of fallen stock samples because there can be a considerable delay between death and collection of samples. Therefore, it is important to know whether these tests perform optimally on autolyzed samples. The Veterinary Laboratories Agency (VLA) selected 250 positive fallen stock samples. These had been detected during routine testing using the Prionics-Check Western blot and confirmed as BSE cases by immunohistochemistry or electron microscopy. Samples were graded according to the degree of autolysis and then tested by the 3 methods: Prionics-Check Western blot, Platelia test, and Enfer test. All 3 methods correctly classified the samples as positive BSE cases, therefore alleviating doubt about their ability to do so. Subsequent EU validation exercises, such as those conducted in 2002--2003, have included the testing of autolyzed material. It is important that all new methods be evaluated on autolyzed tissue before approval for official use.
Pyrazine diuretics. VII. N-Amidino-3-substituted pyrazinecarboxamides (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPyrazine diuretics. VII. N-Amidino-3-substituted pyrazinecarboxamidesJames Holden Jones, Wilbur J. Holtz, and Edward J. Cragoe Jr.Cite this: J. Med. Chem. 1969, 12, 2, 285–287Publication Date (Print):March 1, 1969Publication History Published online1 May 2002Published inissue 1 March 1969https://pubs.acs.org/doi/10.1021/jm00302a019https://doi.org/10.1021/jm00302a019research-articleACS PublicationsRequest reuse permissionsArticle Views445Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Low Power Argon Laser-Induced Thermal Therapy for Subcutaneous Ehrlich Carcinoma in Mice Using Spherical Gold Nanoparticles (2010)

The present study examines the feasibility of a low power argon laser-induced thermal therapy to Ehrlich carcinoma, employing a direct administration of spherical gold nanoparticles (GNPs). This modality utilizes the advantage of strong surface plasmon resonance exhibited by spherical GNPs in the visible range. Ehrlich tumors were grown in female balb mice by subcutaneous injection of Ehrlich ascites carcinoma cells. GNPs with an average diameter 13 +/- 1.2 nm and optical density (ODlambda:518 nm = 3) were directly injected within the tumor interstitium. Tumors were then illuminated with a continuous-wave (CW) argon ion laser with irradiance 55 mW cm-2 for 45 min. All laser-GNPs treated tumors exhibited a significant suppression in tumor growth throughout 15 days. On the contrary, sham-treated group (laser treatment without GNPs injection) and control group (neither laser nor GNPs treatment) showed a progressive increase in tumor growth during the same period. Histopathological examination demonstrated extensive necrotic percentage in laser-GNPs treated group (90%) in comparison with sham (35%) or control group (3-7%). A wide-angle X-ray scattering also revealed detectable changes in tumor protein structure exposed to both laser and GNPs. It can be concluded from this study that the intense surface plasmon resonance exhibited by spherical GNPs in the visible range could be very useful as a noninvasive technique for photothermal therapy of skin or near-surface type tumors that need much less laser energy and lower concentrations of GNPs.
Delayed secondary glucocorticoid responsiveness of MYOC in human trabecular meshwork cells. (2001)

MYOC is a delayed secondary glucocorticoid-responsive gene. Characterization of the transcription factors that mediate the secondary response will shed new light on the pathophysiology of steroid-induced ocular hypertension and glaucoma.