gebhart/patrepeval huggingface dataset:
Automating interface evaluation (1994)

Article Free Access Share on Automating interface evaluation Authors: Michael D. Byrne Graphics, Visualization, and Usability Center, Georgia Institute of Technology, Atlanta, GA Graphics, Visualization, and Usability Center, Georgia Institute of Technology, Atlanta, GAView Profile , Scott D. Wood Electrical Engineering and Computer Science Department, University of Michigan, Ann Arbor, MI Electrical Engineering and Computer Science Department, University of Michigan, Ann Arbor, MIView Profile , James D. Foley Graphics, Visualization, and Usability Center, Georgia Institute of Technology, Atlanta, GA Graphics, Visualization, and Usability Center, Georgia Institute of Technology, Atlanta, GAView Profile , David E. Kieras Electrical Engineering and Computer Science Department, University of Michigan, Ann Arbor, MI Electrical Engineering and Computer Science Department, University of Michigan, Ann Arbor, MIView Profile , Piyawadee Noi Sukaviriya Graphics, Visualization, and Usability Center, Georgia Institute of Technology, Atlanta, GA Graphics, Visualization, and Usability Center, Georgia Institute of Technology, Atlanta, GAView Profile Authors Info & Claims CHI '94: Proceedings of the SIGCHI Conference on Human Factors in Computing SystemsApril 1994 Pages 232–237https://doi.org/10.1145/191666.191752Online:24 April 1994Publication History 24citation713DownloadsMetricsTotal Citations24Total Downloads713Last 12 Months23Last 6 weeks6 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Generation and propagation of an electromagnetic Gaussian Schell-model vortex beam (2015)

We outline the propagation of an electromagnetic Gaussian Schell-model (EGSM) vortex beam through a paraxial ABCD optical system and analyze the vortex phase-induced changes of the statistical properties, such as average intensity, state of polarization, and degree of polarization (DOP), of a focused EGSM beam. It is found that one can shape the beam profile of an EGSM vortex beam in the focal plane through varying its initial topological charge, DOP, and coherence widths. Furthermore, we first report experimental generation of an EGSM vortex beam and measure its focusing properties in experiments. Our experimental results are consistent with the numerical results and may be useful in material thermal processing and particle trapping.
Establishment of a multimarker qPCR panel for the molecular characterization of circulating tumor cells in blood samples of metastatic breast cancer patients during the course of palliative treatment (2016)

Monitoring MBC patients using a multimarker qPCR panel for the characterization of CTC might help to treat patients accordingly in the future.
Kinetics and mechanism of the nucleophilic substitution of arylhalogenoacetylenes by sodium toluene-p-thiolate in NN-dimethylformamide (1973)

The title reaction of 1-chloro- and 1-bromo-2-phenylacetylenes and of their p-Me and p-Cl substituted derivatives has been kinetically studied. Only 1-p-tolylthio-2-arylacetylenes are obtained, provided an excess of thiolate is avoided. By use of excess of thiolate, an addition reaction takes place on the substitution product. Ratios kRCl:kRBr in the range 2·5–4·2 have been found for the substitution at –25°C. Hammett ρ values of 3·4 and 3·9 are calculated for chloro- and bromo-acetylenes, respectively. In agreement with these results, p-NO2·C6H4·CCBr gives a fast substitution even at –50 °C. Results are interpreted on the basis of the α-addition–elimination mechanism for substitution at an acetylenic carbon atom.
Mechanisms for hydrophilic/hydrophobic wetting transitions on cellulose cotton fibers coated using Al2O3 atomic layer deposition (2012)

This report explores reactions that proceed during the first few cycles of inorganic film atomic layer deposition (ALD) on natural cellulose cotton fibers, and how surface reactions can explain the previously observed transitions in surface wetting upon ALD on cotton fibers. Atomic layer deposition of aluminum oxide and zinc oxide onto natural cotton cellulose produces a transition from hydrophilic to hydrophobic, then from hydrophobic back to hydrophilic, and we describe here the main factors that bring about. Interestingly, we show that air exposure and related adventitious carbon adsorption also affects the subsequent reactions and wetting properties obtained after subsequent ALD cycles. X-ray photoelectron spectroscopy and in situ Fourier transform infrared spectroscopy data indicate Al-(O-C-)3 bonding units form when trimethylaluminum interacts with surface –OH units during the first precursor doses, producing a hydrophobic finish on the cotton that remains for only a few ALD cycles. Also, field-emission scanning electron microscopy results show that some surface roughening may occur in the first few ALD cycles, and the roughening of the hydrophobic-finished surface can also promote an increase in measured hydrophobicity.
Differential Transcriptional Regulation of <i>CD161</i> and a Novel Gene, <i>197/15a</i> , by IL-2, IL-15, and IL-12 in NK and T Cells (1998)

Cytokine-mediated enhancement of spontaneous cytotoxicity depends, at least in part, on modulation of the expression of surface molecules responsible for recognition of target cell structures and triggering or inhibition of the cytotoxic machinery. We previously demonstrated that expression of transcription factors (e.g., Egr-1, JunB, and c-Fos) is differentially regulated by IL-2 and IL-12. Here we show that expression of CD161/NKR-P1A, a molecule involved in triggering cytotoxicity, is specifically upregulated by IL-12. CD161 transcription, mRNA accumulation, and surface expression are increased by IL-12. Other cytokines sharing the IL-2R beta- and/or common gamma-chains (i.e., IL-15, IL-4, and IL-7) do not mediate these effects. In an effort to analyze the mechanisms by which IL-2, IL-12, and IL-15 differentially regulate gene transcription, we have isolated a novel gene, 197/15a, the expression of which in NK and T cells is down-regulated by IL-2 and IL-15, up-regulated by IL-12, and not affected by IL-4 and IL-7. IL-2 and IL-15 act, at least in part, repressing 197/15a transcription; their effect on 197/15a mRNA accumulation is partially independent of novel protein synthesis, likely not mediated by JunB, Bcl-2, or Bax, and requires the activity of rapamycin-sensitive molecule(s). The observation that IL-2 and IL-12 differentially modulate CD161 expression suggests the existence of cytokine-specific mechanisms of modulation of spontaneous cytotoxicity based on the regulation of expression of surface molecules involved in target cell recognition and/or triggering of the cytolytic machinery.
Neutralization of interferon‐γ in neonatal SOCS1<sup>−/−</sup> mice prevents fatty degeneration of the liver but not subsequent fatal inflammatory disease (2001)

Mice lacking the suppressor of cytokine signalling-1 (SOCS1) die within weeks of birth with extensive fatty degeneration of the liver, consistent with acute hepatic toxicity to interferon-gamma (IFN-gamma), and inflammation of multiple organs. We show here that treatment for 1 week from birth with neutralizing antibody to IFN-gamma rescues SOCS1-/- mice from lethal liver disease but the mice subsequently succumb to chronic inflammatory lesions characterized by T-lymphocyte infiltration of skeletal muscle, pancreas, lung, liver and skin. Elevated blood levels of eosinophils, neutrophils and platelets were also observed and the thymic lymphocyte population was depleted of CD4+ CD8+ T cells and showed a reduced CD4 : CD8 ratio. All T-cell populations in thymus, spleen and lymph node exhibited an increased proportion of cells bearing the activation marker CD44. These data suggest an important role for SOCS1 in T-lymphocyte regulation.
Antimicrobial Action of Chitosan against Lactic Acid Bacteria Separated from Pickles. (1998)

浅漬けの乳酸菌による変敗を防止するため,キトサンの抗菌作用を調べ,有用性と実用上の問題点を示した.浸透圧の高い調味液をキュウリ浅漬けに使用した場合は品質保持期間が5日以上に延長されたが,その後は乳酸菌の増殖により変敗した.これらの乳酸菌を分離し,性質を調べた結果,Lactobacillus sake及びLeuconostoc mesentesoidesと同定された.キトサンはこれらの乳酸菌に対して強い抗菌作用を有し,食塩無添加の場合,0.01%濃度で60分間処理によりほぼ100%の死滅率を示したが,pH及び食塩など食品成分の影響を受けて低下した.浅漬けの弱酸性(pH5.5),低食塩(3%)の条件下でキトサンの抗菌作用を低下させた食品添加物はカラギーナン,グルタミン酸ナトリウム,酢酸ナトリウム,リンゴ酸ナトリウム,塩化力リウムであり,逆に作用を増強した物質はエチルアルコール及びグリシンであった.
Glycosides and Oligosaccharides in the L-Rhamnose Series (1967)

Naringinase, which was induced from Aspergillus niger, consisted β-D-glucosidase and α-L-rhamnosidase. The former was successfully inactivated by heating the crude enzyme solution at 60°C and pH 6.4_??_6.8, whereas the latter was very stable under such treat-ment. By using this enzyme solution flavonoid gycosides were partially hydrolyzed and prunin from naringin, isosakuranin from poncirin, hesperetin-7-β-D-glucoside from hesperidin and neohesperidin, isoquercitrin from rutin, cosmociin from rhoifolin were obtained respec-tively in good yields. Furthermore kaempherol-3-robinobioside, a new flavonol glycoside, and afzelin were obtained from robinin and kaempheritrin, respectively.
Recent advances in the research of inorganic nanotubes and fullerene-like nanoparticles (2013)

This minireview outlines the main scientific directions in the research of inorganic nanotubes (INT) and fullerene-like (IF) nanoparticles from layered compounds, in recent years. In particular, this review describes to some detail the progress in the synthesis of new nanotubes, including those from misfit compounds; core-shell and the successful efforts to scale-up the synthesis of WS2 multiwall nanotubes. The high-temperature catalytic growth of nanotubes, via solar ablation is discussed as well. Furthermore, the doping of the IF-MoS2 nanoparticles and its influence on the physiochemical properties of the nanoparticles, including their interesting tribological properties are briefly discussed. Finally, the numerous applications of these nanoparticles as superior solid lubricants and for reinforcing variety of polymers are discussed in brief.
The operation of metalorganic bubblers at reduced pressure (1990)

Operating a metalorganic (MO) bubbler at low pressure allows a high flux of MO reagent to be extracted without resorting to high carrier gas flows. This approach is particularly suitable for the MOMBE (metalorganic molecular beam epitaxy) growth of III–V compounds. Using a ‘‘see-through’’ water bubbler, we have compared the theory and practice of reduced-pressure bubbler operation, both with and without a carrier flow. We conclude that the small carrier approach offers a wider flexibility in the choice of reagent flow, and a better stability and day to day repeatability of reagent flow. The reduced pressure operation of triethylgallium (TEGa) and triethylaluminum (TEAl) bubblers is described, in the context of the MOMBE growth of GaAs and AlAs. We show that using the small carrier flow approach, the reagent flow can be accurately controlled and predicted over a wide range.
Correction: New Potential Therapeutic Approach for the Treatment of B-Cell Malignancies Using Chlorambucil/Hydroxychloroquine-Loaded Anti-CD20 Nanoparticles (2013)

Current B-cell disorder treatments take advantage of dose-intensive chemotherapy regimens and immunotherapy via use of monoclonal antibodies. Unfortunately, they may lead to insufficient tumor distribution of therapeutic agents, and often cause adverse effects on patients. In this contribution, we propose a novel therapeutic approach in which relatively high doses of Hydroxychloroquine and Chlorambucil were loaded into biodegradable nanoparticles coated with an anti-CD20 antibody. We demonstrate their ability to effectively target and internalize in tumor B-cells. Moreover, these nanoparticles were able to kill not only p53 mutated/deleted lymphoma cell lines expressing a low amount of CD20, but also circulating primary cells purified from chronic lymphocitic leukemia patients. Their safety was demonstrated in healthy mice, and their therapeutic effects in a new model of Burkitt's lymphoma. The latter serves as a prototype of an aggressive lymphoproliferative disease. In vitro and in vivo data showed the ability of anti-CD20 nanoparticles loaded with Hydroxychloroquine and Chlorambucil to increase tumor cell killing in comparison to free cytotoxic agents or Rituximab. These results shed light on the potential of anti-CD20 nanoparticles carrying Hydroxychloroquine and Chlorambucil for controlling a disseminated model of aggressive lymphoma, and lend credence to the idea of adopting this therapeutic approach for the treatment of B-cell disorders.
Effects of pH and Salt Concentration on Functional Properties of Pumpkin Seed Protein Fractions (2016)

In this study, albumin, globulin and glutelin concentrates with the protein contents of 70.4%, 77.9% and 72.3%, respectively were isolated from deffated pumpkin seed meal. Evaluation of functional properties revealed that water absorption capacity of glutelin was always higher than that of globulin while albumin exhibited the lowest water absorption capacity. Albumin showed the highest oil absorption capacity (6.90 mL/g), followed by globulin (3.00 mL/g) and glutelin (2.27 mL/g). In the pH range 2–10 or salt concentration range 0–1 M, albumin demonstrated the highest foaming properties. Glutelin had the best emulsifying capacity at low pH (2–3). In distilled water, the least gelation concentration of albumin and glutelin was similar (14%) and lower than that of globulin (16%). pH adjustment or salt addition could improve functional properties of the three protein concentrates. Pumpkin seed proteins could be used as good protein ingredients in formulation of new food products. Practical Applications In this study, albumin, globulin and glutelin concentrates were prepared from defatted pumpkin seed meal. The effects of pH and salt concentration on functional properties of the pumpkin seed protein fractions were reported. The investigated functional properties included water and oil absorption capacity, emulsifying capacity, emulsion stability, foaming capacity, foam stability and gelation capacity. The obtained results would be useful for food researchers who look for new protein source as functional ingredient in new food product development.
Supporting sequential assumptions in hybrid verification (2005)

We present a method for using a set of temporal properties (SVA, PSL, OVA, RTL monitors) as environment models for industrial-strength hybrid verification that combines formal methods with constrained random simulation. We demonstrate the effectiveness of the method on real-world designs.
Novel rectangular biphasic and monophasic waveforms delivered by a radiofrequency-powered defibrillator compared with conventional capacitor-based waveforms in transvenous cardioversion of atrial fibrillation (2006)

A low-tilt biphasic waveform from a RF-powered defibrillator (6/6 ms 100/-50 V) is more efficacious than standard monophasic or biphasic waveforms (equivalent voltage) and is similar in efficacy to low-tilt monophasic waveforms.
First Association of Interleukin 12 Receptor Beta 1 Deficiency with Sjögren’s Syndrome (2017)

Apart from persistent antigenic stimulation, which may drive autoimmune inflammation in primary immunodeficiency, evidence on the involvement of interleukin 12 in pathogenesis of SS suggests that the same immunological mechanism may underlie both defense against infection and the maintenance of tolerance. To our knowledge, this is the first report of a case of autoimmunity in the form of SS in a patient with a primary immunodeficiency and one of the rare cases of IL12Rβ1 deficiency with manifested autoimmunity.
Cathode-Ray Magnetization Curve Tracer (1948)

An instrument developed to measure the magnetic properties of materials in a variety of forms by oscillographic techniques is described. Magnetic hysteresis loops can readily be obtained for specimens in rod, powder, tape, or wire form having cross-sectional areas as small as 10−5 cm2 or as large as 0.3 cm2 (¼ in. rod). With slight modifications, the instrument can be adapted to magnetic measurements of materials as a function of frequency, temperature, tension, torsion, or pressure using the appropriate setup.
Optimisation of an enzyme treatment process for sheepskins : a thesis presented in partial fulfilment of the requirements for the degree of Master of Engineering in Bio-Process Engineering at Massey University (Manawatu), New Zealand (2009)

An enzyme treatment process for the pre-tanning of sheepskins has been previously reported by the Leather and Shoe Research Association of New Zealand (LASRA) as an alternative to current industry operations. The newly developed process had marked benefits over conventional processing in terms of a lowered energy usage (73%), processing time (47%) as well as water use (49%), but had been developed as a “proof of principle’’. The objective of this work was to develop the process further to a stage ready for adoption by industry. A process ready for adoption by industry is one that is able to generate good quality products (good quality products are those that has solids removed to industry standards, without visible damages to grain surface, evenly dyed etc.), require minimal changes to plant or operation layout and reduce usage of resources (e.g. water and chemicals).\nMass balancing was used to investigate potential modifications for the process based on the understanding developed from a detailed analysis of preliminary design trials. Results showed that a configuration utilising a 2 stage counter-current system for the washing stages and segregation and recycling of enzyme float prior to dilution in the neutralization stage was a significant improvement. Benefits over conventional processing include a reduction of residual TDS by 50% at the washing stages and 70% savings on water use overall. Benefits over the un-optimized LASRA process are reduction of solids in product after enzyme treatment and neutralization stages by 30%, additional water savings of 21%, as well as 10% savings of enzyme usage.\nThe optimized (new) LASRA process uses existing equipment and requires no additional outlay of capital. The process is now developed to a point where it should be trialled at industrial scale.
Aqueous humor outflow effects of partial thickness channel created by a femtosecond laser in ex-vivo human eyes (2007)

The reduced outflow rate caused by the increased resistance through trabecular meshwork (TM) has been thought to be the main reason for elevated intraocular pressure (IOP). It has been demonstrated that femtosecond laser pulses tuned to 1.7 μm wavelength can create the partial thickness channel in the sclera in ex vivo human eyes [1] and aqueous outflow can be increased by these channels in porcine eyes [2]. It was also shown that the outflow rate is reduced over time in ex vivo human eyes [3]. Therefore, the control experiment without laser treatment at the same condition was conducted and showed that outflow was reduced by 1.5 ± 0.8 μl/min at 15mmHg and 1.8 ± 1.0 μl/min at 25mmHg. However, the outflow rate increased by 0.26 μl/min at 15mmHg and 0.15 μl/min at 25mmHg after the partial thickness channel was created, meaning the amount of increased outflow rate might be more than measured considering the outflow reduction in control experiment. We suggest that the femtosecond laser created partial thickness channel can increase the outflow rate and delay the progression of glaucoma.
A Systematic Methodology for Evaluating the Error Resilience of GPGPU Applications (2016)

The wide adoption of graphics processing units (GPUs) as accelerators for general-purpose applications makes the end-to-end reliability implications of their use increasingly significant. Fault injection is a widely adopted method to evaluate the resilience of applications. However, building a fault injector for general-purpose GPU applications is challenging due to their massive parallelism, which makes it difficult to achieve representativeness while being time-efficient. This paper makes four key contributions. First, it presents a fault-injection methodology to evaluate the end-to-end reliability properties of application kernels running on GPUs. Second, it introduces GPU-Qin, a fault-injection tool that uses real GPU hardware and offers a tunable and efficient balance between the representativeness and the cost of a fault-injection campaign. Third, it characterizes the error resilience characteristics of seventeen application kernels. Finally, it provides preliminary insights on correlations between the algorithmic properties of applications and their error resilience.
Cryptosporidiosis in black South African children. (1988)

The incidence of cryptosporidiosis in young children was determined by staining of faecal specimens with a modified Kinyoun stain. Seventeen of 92 (18,4%) children with diarrhoea and 1 of 29 (3.4%) controls excreted Cryptosporidium oocysts, suggesting that this was an important enteric pathogen in these children.
Synthetic scleral reinforcement materials: I. Development and <i>in vivo</i> tissue biocompatibility response (1994)

The surgical treatment of pathological myopia involves the placement of a band cut from donor sclera around the back of the globe to provide support and to prevent elongation that leads to retinal detachment and blindness. In the search for a synthetic material that would overcome the disadvantages of the donor tissue band, we tested 11 types of bands made from 14 polymers in rabbit eyes. Bands were cut from porous and solid materials, as well as porous materials coated with solids and solid materials with porous patches affixed to the posterior surface. Criteria for suitability and biocompatibility included ease of placement and suturing, stable positioning, and absence of long-term tissue response on a cellular level. Testing included evaluation by the surgeons performing the implantations, measurement of the distance between the band and the globe, determination of fibrous capsule thickness and amount of collagen deposition, and enumeration of macrophages accumulated at the band/capsule interface. Based on the results of these studies, two of the porous materials (expanded polytetrafluoroethylene and porous polyurethane fabric) and two of the composite materials (porous polyurethane fabric coated with polyacrylonitrile and silicone with microvilli cut into the posterior surface) were selected for further study.
Effects of CG Location on the Launch Behavior of Free-Fall Lifeboats (1995)

Abstract The free-fall lifeboat was developed to reduce the risk of injury during evacuation in a maritime emergency. It is a generally accepted concept for lifesaving appliances that currently is in use on many ships and offshore platforms. Three concerns during launch of these lifeboats are the attitude of the boat at water entry, the headway immediately after water entry, and the acceleration forces to which the occupants are subjected. Limited quantitative data is available about the behavior of the boats during launch and, in particular, on the effects of mass distribution on the launch behavior of free-fall lifeboats. The purpose of this paper is to discuss quantitatively the launch behavior of free-fall lifeboats, with particular emphasis on the effects of changes in the location of the CG.
Calculation of electric field effects on the Gibbs free energy of the Al-Li-Mg alloy (2007)

基于 Thomas 费密模型，免费精力被发现的单原子的吉布斯的计算方法。在电场下面的内部潜在的边界条件被定义。为有电场的单原子、复合、稳固的答案的免费精力被建立的吉布斯的计算方法。在电场的影响下面，吉布斯艾尔的免费精力是最敏感的，李和 Mg 由那些列在后面。在解决方案温度吉布斯在电场下面的 Al3Li 和它的元素的免费精力不关于电场的零个点是对称的，而在变老的温度他们的值在附近是对称的，零电场指。在电场的零个点附近的答案温度，吉布斯 Al3Li 的免费精力比 Al-2.14%Li 的高。并且在 460 K 吉布斯 Al3Li 的免费精力是比在电场下面的 Al-2.14wt.%Li 的低的。吉布斯 1420 合金的免费精力在变老的温度从电场的双方减少到零个点。