gebhart/patrepeval huggingface dataset:
An Intrusion Detection System Based on Support Vector Machine (2003)

The generalizing ability of current IDS (intrusion detection system) is poor when given less priori knowledge. Utilizing SVM (support vector machines) in Intrusion Detection, the generalizing ability of IDS is still good when the sample size is small (less priori knowledge). First, the research progress of intrusion detection is recalled and algorithm of support vector machine taxonomy is introduced. Then the model of an Intrusion Detection System based on support vector machine is presented. An example using system call trace data, which is usually used in intrusion detection, is given to illustrate the performance of this model. Finally, comparison of detection ability between the above detection method and others is given. It is found that the IDS based on SVM needs less priori knowledge than other methods and can shorten the training time under the same detection performance
Multivariable feedback design: Concepts for a classical/modern synthesis (1981)

This paper presents a practical design perspective on multivariable feedback control problems. It reviews the basic issue-feedback design in the face of uncertainties-and generalizes known single-input, single-output (SISO) statements and constraints of the design problem to multiinput, multioutput (MIMO) cases. Two major MIMO design approaches are then evaluated in the context of these results.
Effects of Finite Conductivity in Electrorheological Fluids (1991)

Electrorheological (ER) effects arise from electrostatic forces between particles suspended in a carrier fluid, induced when an electric field is applied. These forces are a consequence of field distortion in the neighborhood of each particle. Although it is known that finite conductivity can influence ER effects, the standard assumption has been that the contrast between the dielectric constants of particles and surrounding fluid is responsible for the field distortion. This is likely to be seriously in error with a low-frequency or dc applied field if measurable conductivity is preset in either the particles or fluid. Below a crossover frequency, f{sub c}, field distortion becomes dominated by conductivities, and a variety of other complications may arise. Conductive particles could acquire a net charge and fail to participate in chain formation, and a relatively high fluid conductivity may lead to competing processes, including the possibility of a significant distortion of the field distribution in an ER cell. The latter phenomenon is not directly related to f{sub c} and might occur at frequencies above it. Any of these effects could lead to field dependent or frequency dependent behavior of experimental results. 7 refs., 5 figs.
Membrane Type 1 Matrix Metalloproteinase Regulates Collagen-Dependent Mitogen-Activated Protein/Extracellular Signal-Related Kinase Activation and Cell Migration (2004)

Mitogen-activated protein kinase-extracellular signal-related kinase (ERK) kinase 1 (MEK1)/ERK signaling has been implicated in the regulation of tumor cell invasion and metastasis. Migration of HT1080 cells on type I collagen was suppressed by the matrix metalloproteinase (MMP) inhibitors BB94 and tissue inhibitor of metalloproteinase (TIMP)-2 but not by TIMP-1. TIMP-2-specific inhibition suggests that membrane type 1 MMP (MT1-MMP) is likely involved in this process. Activation of ERK was induced in HT1080 cells adhered on dishes coated with type I collagen, and this was inhibited by BB94. MMP-2 processing in HT1080 cells, which also was stimulated by cultivation on type I collagen, was inhibited by MEK inhibitor PD98059. Expression of a constitutively active form of MEK1 promoted MMP-2 processing concomitant with the increase of MT1-MMP levels, suggesting that MT1-MMP is regulated by MEK/ERK signaling. In addition, expression of the hemopexin-like domain of MT1-MMP in HT1080 cells interfered with MMP-2 processing, ERK activation, and cell migration, implying that the enzymatic activity of MT1-MMP is involved in collagen-induced ERK activation, which results in enhanced cell migration. Thus, adhesion of HT1080 cells to type I collagen induces MT1-MMP-dependent ERK activation, which in turn causes an increase in MT1-MMP levels and subsequent cell migration.
Expression of CD44 variant exon 6 in stage I non-small cell lung carcinoma as a prognostic factor. (1998)

Specific CD44 isoforms are the surface adhesion molecules that have been shown to be associated with metastasis. In the present study, the role of the expression of standard and variant CD44 isoform (CD44s and CD44v6) as prognostic indicators in pathological stage I non-small cell lung carcinoma was investigated immunohistologically using monoclonal antibodies. The results showed that the expression of CD44v6 correlates with adverse prognosis in stage I non-small cell lung carcinoma but not CD44s. The 5-year survival rate of the patients with CD44v6-positive tumors was 50%, which was significantly lower than that of CD44v6-negative patients (88%; P = 0.001). The incidence of recurrent distant metastasis in the CD44v6-positive patients (45%; 9 of 20 patients) was significantly higher than that in the CD44v6-negative patients (20%; 10 of 49 patients; P = 0.038), suggesting the involvement of CD44v6 in hematogeneous metastasis of lung carcinoma. Although the incidence of the expression of CD44v6 in squamous cell carcinoma was significantly higher than that in adenocarcinoma, histological type was not a significant prognostic factor. No significant correlation was found between the expression of CD44v6 and lymphatic or vascular vessel invasion, although lymphatic vessel invasion was found to be an independent prognostic factor in the multivariate analysis. To investigate the relationship between the expression of CD44v6 and proliferative activity of tumor cells, the expression of proliferating cell nuclear antigen (PCNA) was examined. The expression of CD44v6 was more frequently observed in PCNA-positive patients than in PCNA-negative patients (P = 0.019), but the expression of PCNA was not a statistically significant prognostic indicator. The results of multivariate analysis by the Cox proportional hazards model showed that CD44v6 was an independent prognostic indicator. We concluded that the expression of CD44v6 is a useful prognostic factor in stage I non-small cell lung carcinoma.
Role of Serotonin, Histamine, and Thromboxane A2 in Platelet-Induced Contractions of Coronary Arteries and Aortae from Rabbits (1989)

The present study was undertaken to clarify the underlying mechanisms responsible for contractions of isolated coronary arteries and aortae from rabbits in response to thrombin-stimulated autologous platelets. Thrombin-stimulated platelets evoked potent contractions of both arteries in a platelet concentration-related manner. Pretreatment of platelets with aspirin, which almost completely inhibited thromboxane A2 synthesis but not the release reaction of biologic monoamines from platelets, caused only slight suppression of platelet-induced contractions of both arteries. Ketanserin as well as methysergide markedly inhibited aortic contractions to platelets. In contrast, the contractile responses of coronary arteries to platelets were suppressed by methysergide but not by ketanserin. Pretreatment of the arteries with diphenhydramine did not inhibit the aortic responses to platelets, but significantly suppressed coronary arterial contractions induced by higher concentrations of platelets. Phentolamine had no inhibitory effects on the responses of either artery to platelets. Pretreatment of arteries with aspirin did not affect the contractile responses of either artery to platelets. The contractile responses of aortae to exogenously administered serotonin were competitively antagonized by ketanserin, but those of coronary arteries were not. Coronary contractions to serotonin were competitively inhibited by methiothepin and significantly suppressed by methysergide. The contractile responses of both arteries to histamine were antagonized by diphenhydramine but not by cimetidine. On the basis of our results obtained from studies in organ chamber, we conclude that a major role of thromboxane A2 was not demonstrated in platelet-induced contractions of the arteries, and that those of aortae were mainly mediated by platelet-derived serotonin at S2 receptor and those of coronary arteries at S1-like receptor. The contractions of coronary arteries in responses to higher concentrations of platelets were partly mediated by histamine at H1 receptor.
Phage-Host Interaction: an Ecological Perspective (2004)

Nearly 100 years ago, Felix d'Herelle, the codiscoverer of bacteriophages, used bacteria to control insect pests and used phages against bacterial disease.His approaches reflected ecological insights before this branch of biology became an established scientific discipline.In fact, one might have predicted that phage research would become the springboard for biotechnology and ecology.However, d'Herelle was ahead of his time, and the zeitgeist in the 1930s pushed physicists into the question "What is life?"Phages as the simplest biological systems were the logical choice for this question, and phage research became the cradle of molecular biology.Now many researchers speak of a "new age of phage research."It is now realized that phages play an important role in ecology (e.g., phage impact on the cycling of organic matter in the biosphere at a global level) ( 27), that phages influence the evolution of bacterial genomes (most obviously in the development of bacterial pathogenicity) (7), and that phages might provide potential tools to face the antibiotic resistance crisis in medicine (59).With this new trend, we now see a clear shift from the reductionist approach, focusing on a handful of phages in carefully controlled laboratory conditions, towards the study of many different phages in the complexity of real-life situations.In contrast to the molecular biology-oriented phage research where the interaction of molecules took center stage, ecology focuses on the interactions between organisms and their physical environment.Much of ecology is therefore about the evolution of biological diversity in space and time.In contrast to many branches of biology, ecology attributes a great importance to quantitative relationships and numbers and aims at a mathematical formulation of its observations.It is thus appropriate to start this review with an overview of phage titers encountered in the biosphere.Next, we ask how a parasite targets its host if the latter is scarce or not in an appropriate physiological state.Finally, we report on research that tries to bridge phage ecology and genomics and cell biology approaches.It is concluded that the integration of phages into complex networks of interacting biological systems, and analysis by molecular techniques, could give phage research a model character in biology again.
Working principle description of the wireless passive EM transduction pressure sensor (2011)

The development of a new passive wireless pressure sensor, based on an electromagnetic transduction approach, is reported. The sensing element is a flexible high resistivity silicon membrane located above a coplanar quarter-wavelength resonator. The comprehensive coverage of the physical bases is beyond the scope of this paper. For the remote extraction of the applied pressure value, the passive pressure sensor is connected to a broadband horn antenna via a coaxial delay line. When interrogated by a frequency modulated continuous wave radar, the level of the backscattered signal changes versus the pressure applied to the proof body. Through this interrogation principle, the sensor provides load impedance that is reflected back to the radar reader: the measured dynamic is about 0.8 dBm/bar. This completely passive and wireless pressure telemetry micro-sensor has been designed, fabricated and characterized, thereby eliminating the need for contact, signal processing circuits, and power supplies needed by conventional active sensors.
The Hundredth Psalm to the Tune of "Green Sleeves": Digital Approaches to Shakespeare's Language of Genre (2010)

In this essay, Hope and Witmore explore the linguistic matrix of Shakespeare's dramatic genres by using multivariate statistics and a text-tagging device known as DocuScope, a hand-curated corpus of several million English words (and strings of words) that has been sorted into grammatical, semantic, and rhetorical categories. Starting with Heminges and Condell's designations of the Folio plays as comedies, histories, and tragedies, the authors offer a portrait of Shakespearean genre at the sentence level, showing how identifying frequently iterated word combinations (in either their presence or absence) allows new ways to study the integrity and fluidity of Shakespeare's genres. Calling this approach criticism, they situate their critical practice within both Shakespearean criticism and humanities-centered protocols of reading, concluding with a genre map of Shakespeare's plays compared to nearly three hundred other early modern dramas. Hope and Witmore do not seek to replace subjective, humanistic reading with something more objective. Rather, they use digital, iterative methods in order to be consistently subjective—to extend interpretative strategies across quantities of texts and frequencies of feature that could otherwise not be accommodated.
Intersystem Access Control Protocol Description (1985)

This paper describes one layer in the Intersystem protocol hierarchy, which is a mechanism for internetworking among existing and planned military satellite communication systems. With this mechanism, the combined systems form a world-wide satellite communication network serving tens of thousands of end users, many of whom are mobile, using many different communication link protocols. Since the interconnection of separate communication systems via the Intersystem is not allowed to change their internal structure or communication protocols, the Intersystem protocol hierarchy is primarily a common set of higher layer coordination protocols that will overlay the existing protocols in each member system. This paper describes the higher layer coordination protocols.
Canada (1950)

Canada Get access Canada. Ed. by George W. Brown. Cambridge, University Press; Berkeley and Los Angeles, University of California Press, 1950. xviii+621 pp. Illus. Maps. Tables. Bibliog. Index. (United Nations Series. Ed. by Robert J. Kerner.) 834′​′×534′​′ 45s. $6.50. G. S. Graham G. S. Graham Search for other works by this author on: Oxford Academic Google Scholar International Affairs, Volume 26, Issue 4, October 1950, Page 557, https://doi.org/10.2307/2607183 Published: 01 October 1950
Polyamic Acid Nanofibers Produced by Needleless Electrospinning (2010)

The polyimide precursor (polyamic acid) produced of 4, 4 ′ ‐oxydiphthalic anhydride and 4, 4 ′ ‐oxydianiline was electrospun using needleless electrospinning method. Nonwoven layers consisting of submicron fibers with diameters in the range about 143–470 nm on the polypropylene spunbond supporting web were produced. Filtration properties of these nanofiber layers on the highly permeable polypropylene support—namely filtration effectivity and pressure drop—were evaluated. Consequently, these polyamic acid fibers were heated to receive polyimide nanofibers. The imidization process has been studied using IR spectroscopy. Some comparisons with the chemically identical polyimide prepared as the film were made.
Thermal denaturation of antithrombin III. Stabilization by heparin and lyotropic anions. (1981)

Antithrombin III is of potential value for replacement therapy in patients with acquired or congenital deficiencies. Pasteurization of the purified inhibitor for 10 h at 60 degrees C can reduce the risk of transfusion hepatitis. Addition of appropriate stabilizers can largely prevent the loss of antithrombin activity which otherwise occurs during pasteurization. Studies of the mechanism of denaturation and stabilization have been facilitated by the use of 8-anilino-1-naphthalene sulfonate which binds weakly to the inhibitor and whose fluorescence undergoes a sigmoidal response to increasing temperature. The extent of the increase in 8-anilino-1-naphthalene sulfonate fluorescence correlates roughly with the loss of antithrombin activity and with the extent of protein aggregation as determined by high pressure liquid chromatography. The midpoint, Td, of the thermal denaturation curve increases by 13 degrees C and 19 degrees C in the presence of 0.5 M and 1.0 M sodium citrate, respectively. Phosphate, sulfate, and EDTA are also strong stabilizers while the chaotropic anions, iodide and thiocyanate are potent destabilizers. Heparin at 10 mg/ml increases Td by 7 degrees C, presumably through a direct binding mechanism; chondroitin sulfate and hyaluronic acid have no effect. Samples pasteurized for 10 h at 60 degrees C in the presence of 0.5 M and 1.0 M citrate retain essentially full activity but exhibit evidence of minor alterations in their interaction with heparin.
Usefulness of Color Doppler Sonography in a Growing Skull Fracture (1997)

A case of an 11-month-old infant with a growing skull fracture is described. The patient was admitted with disturbance of consciousness and left hemiparesis after a severe head injury. A pulsating protrusion appeared over the fracture line 1 month later. Color Doppler sonography revealed cerebral herniation and cystic lesion via the bony defect, together with an intracranial arterial flow pattern detected in the extracranial space. Color Doppler sonography was very useful in the diagnosis of growing skull fracture and in the evaluation of the intracranial state, including hemodynamics in this case. Successful surgical treatment was performed on the basis of sonographic data and the patient was discharged 3 months later without motor deficits.
Antimicrobial activity of Bacillus megaterium strains (2012)

A bacterial strain with a high level of antimicrobial activity was isolated from soil and identified as Bacillus megaterium. Production of antibiotics by nine strains of this species from the collection of the State Research Institute for Genetics and Selection of Industrial Microorganisms was investigated. In submerged cultures, nine out of ten B. megaterium strains were found to produce antibacterial antibiotics differing in their spectra of action. Physicochemical characteristics of five compounds were described. Three of them belonged to peptide antibiotics. All five compounds were active against the methicillin-resistant strain Staphylococcus aureus INA 00761. Three of them were shown to be the previously undescribed compounds. Antibiotics produced by various B. megaterium strains were also active against the Leuconostoc mesenteroides VKPM B-4177 strain resistant to glycopeptide antibiotics and against gram-negative bacteria Pseudomonas aeruginosa ATCC 27853 and Escherichia coli ATCC 25922.
Radio access network coordination framework toward 5G mobile wireless networks (2015)

This paper presents a framework to coordinate the operation of radio nodes for the future fifth generation (5G) mobile wireless networks. Based on software-defined operation, we introduce entities of the control plane and interaction among them in this framework. The framework brings a number of benefits. It adapts radio coordination to network and traffic dynamics, enables flexible, on-demand radio node optimization, and reduces coordination overhead in bandwidth, energy and processing power. To verify the effectiveness of the proposed framework, a network deployment scenario is simulated. The results show that our framework could significantly improve the performance in terms of quality of experience, computational complexity, and energy efficiency.
Serum Aminoglycoside Assay by Enzyme-Mediated Immunoassay (EMIT): Correlation with Radioimmunoassay, Fluoroimmunoassay, and Acetyltransferase and Microbiological Assays (1981)

Enzyme-mediated immunoassay (EMIT) serum aminoglycoside assay results were accurate and precise and correlated well with radioimmunoassay, fluoroimmunoassay, and acetyltransferase and microbiological assay determinations.
TCP-R: TCP mobility support for continuous operation (2002)

The TCP-R (TCP Redirection) is an extension of TCP, which maintains active TCP connections when the disconnection occurs due to the change of the IP address or the change of the network device. In mobile computing environments, the IP address may be changed frequently as the host moves across subnets or changes a network device. However, it is difficult for most network applications to work continuously in such a situation. There is much research to support such dynamics in the network layer, but these attempts in the IP layer tend to incur some complexity. This paper is intended as an investigation of the end-to-end mobility support in transport layer. We developed the simple and secure redirection mechanism in TCP, which enables us to keep our working activities without any intermediate agents. We also show that TCP-R can serve as a solution to the retransmission timeout problem which frequently occurs in mobile environments. We implemented and evaluated a prototype of TCP-R by modifying FreeBSD. The measured performance indicates that TCP-R can maintain operation continuously with minimal overhead and complexity.
Successful Gene Therapy for Severe Combined Immunodeficiency (2002)

Infants with severe combined immunodeficiency are unable to mount an adaptive immune response, because they have a profound deficiency of lymphocytes. These babies usually die within a year from a sustained onslaught of opportunistic infections, but death can also be caused by immunization with live viral vaccines or with bacille Calmette–Guérin for the prevention of tuberculosis. Poliomyelitis, polioencephalitis, giant-cell pneumonia (caused by the measles virus), and fatal progressive vaccinia are other consequences of immunization of these infants. In fact, infants with severe combined immunodeficiency present a pediatric emergency to the physician; they can survive only if an immune system is . . .
Late Permian plants including Charophytes from the Khuff Formation of Saudi Arabia (1983)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Hypoaminoacidemia Characterizes Chronic Traumatic Brain Injury (2016)

Individuals with a history of traumatic brain injury (TBI) are at increased risk for a number of disorders, including Alzheimer's disease, Parkinson's disease, and chronic traumatic encephalopathy. However, mediators of the long-term morbidity are uncertain. We conducted a multi-site, prospective trial in chronic TBI patients (∼18 years post-TBI) living in long-term 24-h care environments and local controls without a history of head injury. Inability to give informed consent was exclusionary for participation. A total of 41 individuals (17 moderate-severe TBI, 24 controls) were studied before and after consumption of a standardized breakfast to determine if concentrations of amino acids, cytokines, C-reactive protein, and insulin are potential mediators of long-term TBI morbidity. Analyte concentrations were measured in serum drawn before (fasting) and 1 h after meal consumption. Mean ages were 44 ± 15 and 49 ± 11 years for controls and chronic TBI patients, respectively. Chronic TBI patients had significantly lower circulating concentrations of numerous individual amino acids, as well as essential amino acids (p = 0.03) and large neutral amino acids (p = 0.003) considered as groups, and displayed fundamentally altered cytokine-amino acid relationships. Many years after injury, TBI patients exhibit abnormal metabolic responses and altered relationships between circulating amino acids, cytokines, and hormones. This pattern is consistent with TBI, inducing a chronic disease state in patients. Understanding the mechanisms causing the chronic disease state could lead to new treatments for its prevention.