gebhart/patrepeval huggingface dataset:
A privacy-preserving social-aware incentive system for word-of-mouth advertisement dissemination on smart mobile devices (2012)

The recent penetration of smart mobile devices into the consumer market sets a stage for novel network applications. In particular, we envision a paradigm shift in the commercial advertising model facilitated by the widespread uses of these devices: advertisements circulate in a word-of-mouth fashion among device users and reach potential customers based on the users' knowledge about their contacts. In this paper, we identify two major challenges baffling the deployment of such an application: users' selfishness and their privacy concerns. We address the selfishness issue by proposing an incentive scheme which aligns users' interest with that of advertisers in a way that the users are willing to fully explore their social knowledge for effective advertisement deliveries - the emphasis is not only on users' participation but also on the extent and effectiveness of their contributions. We address the privacy concerns by designing a privacy-preserving evidence-collection mechanism, on which the incentive scheme is based. In addition, our design is 1) appealing to advertisers by guaranteeing effectiveness and controllability of the incentive dispensing and 2) robust against users' misbehaviors. We perceive incentive and enforcement as the keys to unlock the power of users' collective intelligence for effective information dissemination.
Disappearance of Hyperplastic Polyps in the Stomach after Eradication of <i>Helicobacter pylori</i> (1998)

Most hyperplastic polyps disappeared after eradication of H. pylori. Thus, eradication should be attempted before endoscopic removal is done in patients with hyperplastic gastric polyps and H. pylori infection.
Genotoxicity induced by saponified coconut oil surfactant in prokaryote systems (2004)

Surfactants are amphiphilic substances with special properties and chemical structures that allow a reduction in interfacial tension, which permits an increase in molecule solubilization. The critical micelle concentration (CMC) is an important characteristic of surfactants that determines their aggregate state, which is generally related to its functional mechanism. In this work the genotoxic potential of saponified coconut oil (SCO), a surfactant obtained from Cocos nucifera, was analyzed using prokaryote systems. DNA strand breaks were not observed after treatment of a plasmid with SCO. Negative results were also obtained in the SOS Chromotest using Escherichia coli strains PQ35 and PQ37. A moderate toxicity of SCO was observed after treatment of strain CC104 with a concentration above its CMC, in which micelles were found. Nevertheless, this treatment was not cytotoxic to a CC104mutMmutY strain. Furthermore, in this DNA repair-deficient strain treatment with a SCO dose below its CMC, in which only monomers were found, demonstrated the possibility of an antioxidant effect, since a reduction in spontaneous mutagenesis frequency was observed. Finally, in an Ames test without metabolic activation mutagenicity induction was observed in strains TA100 and TA104 with treatment doses below the CMC. The cytotoxic, antioxidant and mutagenic effects of SCO can be influenced by the aggregational state.
A unifying service discipline for providing rate-based guaranteed and fair queuing services based on the Timed Token protocol (2002)

Multiservice networks face the challenge of managing several traffic classes simultaneously. Service disciplines devised for multiservice networks therefore need to be flexible, i.e., able to provide different types of service, in order to accommodate different traffic classes efficiently. In this paper, we present and analyze an innovative Timed Token Service Discipline (TTSD, which has been given Patent Application No. TO2000A001000) which is able to schedule both rate-guaranteed and best-effort traffic simultaneously at a feasible computational complexity. The service paradigm approximated by TTSD is unveiled by means of a fluid-flow analysis and proven to be different from the well-known Generalized Processor Sharing. We then describe the TTSD properties, deriving minimum rate guarantees and delay bounds for leaky-bucket constrained traffic, both in a single node and in a multinode environment. Furthermore, algorithms for selecting the TTSD parameters in order to achieve a prespecified rate and delay guarantees are proposed.
The convergence angle in teeth prepared for artificial crowns (1978)

The bucco-lingual and mesio-distal convergence angles in vital and rootfilled teeth prepared for complete crowns were measured microscopically on 190 stone dies. In vital teeth the mean convergence angles varied between approximately 19 and 27 degrees. In rootfilled teeth the mean angles varied between 12 and 37.
Biomimetic Total Syntheses of Flinderoles B and C (2011)

A simple and efficient biomimetic synthesis of pyrrolo[1,2-a]indoles using a highly stereo- and regioselective [3 + 2] reaction cascade was developed and then further applied in the first total synthesis of flinderoles B and C, which proceeded in 17.2% yield over the longest linear sequence of 11 steps.
The Stereochemistry of Asymmetric Phosphorus Compounds. II. Stereospecificity in the Irreversible Inactivation of Cholinesterases by the Enantiomorphs of an Organophosphorus Inhibitor (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Stereochemistry of Asymmetric Phosphorus Compounds. II. Stereospecificity in the Irreversible Inactivation of Cholinesterases by the Enantiomorphs of an Organophosphorus InhibitorHerbert S. Aaron, Harry O. Michel, Benjamin Witten, and Jacob I. MillerCite this: J. Am. Chem. Soc. 1958, 80, 2, 456–458Publication Date (Print):January 1, 1958Publication History Published online1 May 2002Published inissue 1 January 1958https://pubs.acs.org/doi/10.1021/ja01535a052https://doi.org/10.1021/ja01535a052research-articleACS PublicationsRequest reuse permissionsArticle Views125Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Genetic Basis of Cellular Recovery from Radiation Damage: Response of the Radiosensitive irs Lines to Low-Dose-Rate Irradiation (1995)

Recovery from the lethal effects of irradiation is commonly found when cultured mammalian cells are irradiated at low dose rates when compared to the same cells irradiated at higher dose rates. However, this cellular recovery process is severely reduced or absent in a number of radiosensitive cell lines, including those derived from the human disorder ataxia telangiectasia (AT). The genetic and molecular basis of such recovery processes is not understood, despite their importance. The responses of cells of three further radiosensitive lines, irs1, irs2 and irs3, shown previously to be mutated in different genes, to low-dose-rate radiation are now presented. Plateau-phase cultures of cells of the irs2 line were found to have little or no cellular recovery, while irs1 and irs3 had considerable recovery potential. In comparing the known properties of the radiosensitive lines lacking cellular recovery, including xrs, XR-1 and scid as well as AT and irs2, it is argued that the gene products lacking in these lines normally act coordinately in a specific damage-recognition pathway. The recovery pathway is likely to be associated with the rejoining of DNA double-strand breaks, since several of these recovery-defective lines have a measurable deficiency in break repair.
Presymptomatic analysis of spinocerebellar ataxia type 1 (SCA1) via the expansion of the <i>SCA1</i> CAG-repeat in a large pedigree displaying anticipation and parental male bias (1993)

Autosomal dominant cerebellar ataxia type 1 (ADCA1) is a clinical and genetic heterogeneous neurodegenerative disorder which leads to progressive cerebellar ataxia. One defective gene responsible for the disease was first localised to 6p (SCA1, spinocerebellar ataxia type 1) and the mutation has been more recently characterised. We have analysed the CAG-repeat mutation responsible for the SCA1 phenotype in a large Spanish kindred with 41 affected members, in which positive linkage with D6S89 was previously shown. All (10) clinically affected members analysed were heterozygous with one disease allele being between 41 to 57 CAG repeats, and the other in the normal range, from 6 to 39 repeats. Nine clinically unaffected individuals who were between the ages of 18 and 40, were found to have expansions of the CAG repeat (41 to 59), and 22 other 'at risk' individuals were found to have inherited the SCA1 gene with copies of the CAG repeat in the normal range. We have also observed that affected fathers passed on the mutated SCA1 gene with larger increases in the number of CAG repeats than affected mothers did. In one case a decrease in the number of CAG repeats (51 to 50) was detected in the transmission from the affected mother, and in two cases no change was observed in the transmission of a 41 allele repeat by a mother. As in the other disorders in which knowledge of the mutation has been obtained, analysis of the repeat expansion dramatically changes diagnosis of SCA1.
Performance Analysis of Software-Defined Networking (SDN) (2013)

Software-Defined Networking (SDN) approaches were introduced as early as the mid-1990s, but just recently became a well-established industry standard. Many network architectures and systems adopted SDN, and vendors are choosing SDN as an alternative to the fixed, predefined, and inflexible protocol stack. SDN offers flexible, dynamic, and programmable functionality of network systems, as well as many other advantages such as centralized control, reduced complexity, better user experience, and a dramatic decrease in network systems and equipment costs. However, SDN characterization and capabilities, as well as workload of the network traffic that the SDN-based systems handle, determine the level of these advantages. Moreover, the enabled flexibility of SDN-based systems comes with a performance penalty. The design and capabilities of the underlying SDN infrastructure influence the performance of common network tasks, compared to a dedicated solution. In this paper we analyze two issues: a) the impact of SDN on raw performance (in terms of throughput and latency) under various workloads, and b) whether there is an inherent performance penalty for a complex, more functional, SDN infrastructure. Our results indicate that SDN does have a performance penalty, however, it is not necessarily related to the complexity level of the underlying SDN infrastructure.
Recent progress on arrayed-waveguide grating multi/demultiplexers based on silica planar lightwave circuits (2008)

This paper reports recent advances on arrayed waveguide grating (AWG) multi/demultiplexers based on silica-based planar lightwave circuits (PLC). After briefly summarizing the fabrication and properties of PLCs, this work describes a Mach-Zehnder interferometer (MZI)-synchronized AWG with reagrd to reduced loss, and athermalization. The paper then reports our recent demonstration of the integration of a PLC-based wavelength selective switch (WSS) and an integrated single-chip VMUX/DEMUX.
Development of high-thermal-conductive SiC ceramics (1988)

Large semiconductor chips generate greater heat. Therefore, heat dissipation has become a serious problem. To dissipate heat from semiconductor chips, a new type of substrate material is needed. A new generation of SiC ceramics has been developed which is suitable as substrate materials for Si semiconductors.
A New Distributed Method for Training Generative Adversarial Networks (2021)

Generative adversarial networks (GANs) are emerging machine learning models for generating synthesized data similar to real data by jointly training a generator and a discriminator. In many applications, data and computational resources are distributed over many devices, so centralized computation with all data in one location is infeasible due to privacy and/or communication constraints. This paper proposes a new framework for training GANs in a distributed fashion: Each device computes a local discriminator using local data; a single server aggregates their results and computes a global GAN. Specifically, in each iteration, the server sends the global GAN to the devices, which then update their local discriminators; the devices send their results to the server, which then computes their average as the global discriminator and updates the global generator accordingly. Two different update schedules are designed with different levels of parallelism between the devices and the server. Numerical results obtained using three popular datasets demonstrate that the proposed framework can outperform a state-of-the-art framework in terms of convergence speed.
Yield Editor: Software for Removing Errors from Crop Yield Maps (2007)

Yield maps are a key component of precision agriculture, due to their usefulness in both development and evaluation of precision management strategies. The value of these yield maps can be compromised by the fact that raw yield maps contain a variety of inherent errors. Researchers have reported that 10 to 50% of the observations in a given field contain significant errors and should be removed. Methods for removing these outliers from raw yield data have not been standardized, although many different filtering techniques have been suggested to address specific error types. We developed a software tool called Yield Editor to simplify the process of applying filtering techniques for yield data outlier detection and removal. Yield Editor includes a map view of the yield data, allowing the user to interactively set, assess the effects of, and refine a number of previously reported automated filtering methods. Additionally, Yield Editor allows manual selection of erroneous points, transects, or regions for investigation and possible deletion. This paper describes the filters implemented in Yield Editor, discusses input, output, and filtering options, and documents availability of the program. Example applications of Yield Editor on five test fields are used to show how the user interacts with the software and to analyze the relative importance of the various filters.
A 3.0 μs Room Temperature Excited State Lifetime of a Bistridentate Ru<sup>II</sup>−Polypyridine Complex for Rod-like Molecular Arrays (2006)

A bistridentate RuII-polypyridine complex [Ru(bqp)2]2+ (bqp = 2,6-bis(8'-quinolinyl)pyridine) has been prepared, which has a coordination geometry much closer to a perfect octahedron than the typical Ru(terpyridine)2-type complex. Thus, the complex displays a 3.0 mus lifetime of the lowest excited metal-to-ligand charge transfer (3MLCT) state at room temperature. This is, to the best of our knowledge, the longest MLCT state lifetime reported for a RuII-polypyridyl complex at room temperature. The structure allows for the future construction of rod-like, isomer-free molecular arrays by substitution of donor and acceptor moieties on the central pyridine units. This makes it a promising photosensitizer for applications in molecular devices for artificial photosynthesis and molecular electronics.
Neuroprotective Doses of N-Methyl-D-Aspartate Receptor Antagonists Profoundly Reduce the Minimum Alveolar Anesthetic Concentration (MAC) for Isoflurane in Rats (1993)

N-methyl-D-aspartate (NMDA) receptor antagonists, which block one of the glutamate receptors, have provided evidence of cerebral protection in animal models of focal cerebral ischemia. We examined the effect of neuroprotective doses of one noncompetitive (dizocilpine) and two competitive (D-CPP-ene, CGS 19755) NMDA antagonists on the minimum alveolar anesthetic concentration (MAC) of isoflurane in rats. A single bolus injection of any of the three NMDA antagonists produced a significant (P < 0.01) and sustained (> 3 h) decrease in the MAC of isoflurane. Dizocilpine decreased MAC by 33%-38% at a dose of 0.15 mg/kg and 48%-54% at a dose of 0.5 mg/kg. D-CPP-ene decreased MAC by 32%-37% at a dose of 1.5 mg/kg and 39%-45% at a dose of 4.5 mg/kg. CGS 19755 decreased MAC by 19%-24% at a dose of 3 mg/kg and 49%-58% at a dose of 10 mg/kg. Dizocilpine, but not the competitive antagonists, produced a small transient decrease in mean arterial blood pressure. The sustained anesthetic potency of neuroprotective doses of NMDA antagonists supports the idea that glutaminergic receptor activity is involved in determining the anesthetic state.
The discrete-time bounded-real lemma in digital filtering (1985)

The Lossless Bounded-Real lemma is developed in the discrete-time domain, based only on energy balance arguments. The results are used to prove a discrete-time version of the general Bounded-Real lemma, based on a matrix spectral-factorization result that permits a transfer matrix embedding process. Some applications of the results in digital filter theory are finally outlined.
Human papillomavirus 16 DNA immortalizes two types of normal human epithelial cells of the uterine cervix. (1992)

Premalignant cervical lesions occur at the squamo-columnar junction and in endocervical epithelium and squamous ectocervical epithelium, in descending order of frequency. However, previously only ectocervical cells have been clearly shown to be immortalized in vitro by the oncogenic human papillomaviruses (HPVs). This report describes the immortalization of normal human ecto- and endocervical epithelial cells by the intact HPV 16 genome. Ectocervical epithelial cells (HEC) became immortalized (HEC-16) without crisis while endocervical cells (HEN) were immortalized (HEN-16) after undergoing crisis. HEN-16 and HEC-16 contained integrated HPV 16 DNA, expressed E6 and E7 mRNA, and were aneuploid and nontumorigenic. They also expressed cytokeratins in a pattern similar to their distinct normal parental cells. These results suggest that both squamous and simple epithelial cells of uterine cervix are targets for immortalization by HPV 16.
RADIATION-INDUCED REDUCTION OF AROMATIC CARBOXYLIC ESTERS IN ALCOHOLIC SOLUTIONS (1980)

Abstract Gamma-irradiation of aromatic carboxylic esters in alcoholic solutions brings about the reduction of the ester group to aldehyde, alcohol, α-ketoalcohol, and 1,2-glycol. The reduction is effected by solvated electrons and solvent-derived hydroxyalkyl radicals.
Network coding and error correction (2003)

We introduce network error-correcting codes for error correction when a source message is transmitted to a set of receiving nodes on a network. The usual approach in existing networks, namely link-by-link error correction, is a special case of network error correction. The network generalizations of the Hamming bound and the Gilbert-Varshamov bound are derived.
In Vitro Analysis of Stable, Receptor-Selective Neurotensin[8−13] Analogues (2003)

A set of neurotensin[8-13] (NT[8-13]) analogues featuring substitution of non-natural cationic amino acids in the Arg(8) position have been synthesized and tested for binding potencies against the three cloned human NT receptors (hNTR-1, hNTR-2, hNTR-3), functional agonism of the hNTR1 and for rat serum stability. Three distinct classes of peptides have been identified: Class 1 features alkyl-Arg analogues at Arg(8), Class 2 features alpha-azido-cationic amino acids at Arg(8), and Class 3 feature modified Arg(8) and Tyr(11) residues. Most of the peptides maintain or exceed the binding potency of NT[8-13] to hNTR-1. Class 2 analogues exceed the binding potency of NT[8-13] to hNTR-2 with KK19 binding with higher affinity to hNTR-2 than hNTR-1. Peptides with enhanced binding potencies for hNTR-3 were not found. All analogues are functional agonists of the hNTR1 receptor as indicated by phosphoinositide (PI) determination. Serum stability increased with peptide classification where the half-life of Class 1 < Class 2 < Class 3 which are stable to rat serum for > 24 h.
The integration of GaAs vertical-cavity surface emitting lasers onto silicon circuitry (2002)

An InGaAs-AlGaAs vertical cavity surface emitting laser has been integrated following substrate removal onto a CMOS inverter chip. Digital modulation of the laser is shown.
Communicating Using Spatial Mode Multiplexing: Potentials, Challenges, and Perspectives (2019)

Time, polarization, and wavelength multiplexing schemes have been used to satisfy the growing need of transmission capacity. Using space as a new dimension for communication systems has been recently suggested as a versatile technique to address future bandwidth issues. We review the potentials of harnessing the space as an additional degree of freedom for communication applications including free space optics, optical fiber installation, underwater wireless optical links, on-chip interconnects, data center indoor connections, radio frequency, and acoustic communications. We focus on the orbital angular momentum (OAM) modes and equally identify the challenges related to each of the applications of spatial modes and the particular OAM modes in communication. We further discuss the perspectives of this emerging technology. Finally, we provide the open research directions and discuss the practical deployment of OAM communication links for different applications.
Cyclization of the Enol Esters of <i>o</i>‐Acyloxyphenyl Alkyl Ketones, IV. A kinetic study of the steps of the K<scp>OSTANECKI</scp>‐R<scp>OBINSON</scp> reaction (1969)

Abstract In a study of the K OSTANECKI ‐R OBINSON reaction of 2,4‐diacetoxy‐6‐hydroxy‐propiophenone the rate constants and the order of each step have been approximately determined and compared. Mechanism for the reaction is suggested.
Efficient induction of T‐cell responses to carcinoembryonic antigen by a heterologous prime‐boost regimen using DNA and adenovirus vectors carrying a codon usage optimized cDNA (2005)

The immunogenic properties of plasmid DNA and recombinant adenovirus (Ad) encoding the carcinoembryonic antigen (CEA) were examined in mice by measuring both the amplitude and type of immune response, and the immunogenicity of codon usage optimized cDNA encoding CEA (CEAopt) was assessed both in C57Bl/6 and CEA transgenic mice. Vectors were injected into quadriceps muscle either alone or in combination, and plasmid DNA was electroporated to enhance gene expression efficiency and immunogenicity. Injection of plasmid pVIJ/CEA followed by Ad-CEA boost elicited the highest amplitude of both CD4+ and CD8+ T-cell response to the target antigen, measured by both IFNgamma-ELIspot assay and intracellular staining. Vectors carrying cDNA of CEAopt expressed a greater amount of the CEA protein than their wild-type counterparts, and this enhanced expression was associated with greater immunogenicity. Both CD4+ and CD8+ T-cell epitopes were mapped in the C-terminal portion of the protein. In CEA transgenic mice, only immunization based on repeated injections of pVIJ/CEAopt followed by Ad-CEAopt was able to elicit a CEA-specific CD8+ T-cell response, whereas the wild-type vectors did not break tolerance to this target antigen. MC38-CEA tumor cells injected s.c. in CEA transgenic mice vaccinated with CEAopt vectors exhibited delayed growth kinetics. These studies demonstrate that this type of genetic vaccine is highly immunogenic and can break tolerance to CEA tumor antigen in CEA transgenic mice.