gebhart/patrepeval huggingface dataset:
Crystal structure of monoclinic sulfur (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCrystal structure of monoclinic sulfurLieselotte K. Templeton, David H. Templeton, and Allan. ZalkinCite this: Inorg. Chem. 1976, 15, 8, 1999–2001Publication Date (Print):August 1, 1976Publication History Published online1 May 2002Published inissue 1 August 1976https://pubs.acs.org/doi/10.1021/ic50162a059https://doi.org/10.1021/ic50162a059research-articleACS PublicationsRequest reuse permissionsArticle Views566Altmetric-Citations49LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Characterization of the linker peptide of the single‐chain F<sub>v</sub> fragment of an antibody by NMR spectroscopy (1993)

A comparison of the single-chain Fv fragment of the antibody McPC603 (scFv) with its corresponding unlinked Fv fragment has been carried out with 15N-edited NMR spectroscopy. The two Fv fragments adopt the same structure, indicating that the linker does not perturb the folding of the domains. This also directly demonstrates that folding in vivo (Fv fragment) and in vitro (scFv fragment) leads to the same structure. The main differences in the spectra of the uniformly 15N-labeled scFv and Fv fragments are due to signals of Gly and Ser from the linker peptide of the scFv fragment. The linker peptide has been mapped with NMR spectra of 15N-glycine- and 15N-glycine/15N-serine-labeled scFv fragments. The 15N T2 relaxation data indicate that the linker peptide is more flexible than the rest of the molecule.
Hyperimmune Bovine Colostrum as a Low-Cost, Large-Scale Source of Antibodies with Broad Neutralizing Activity for HIV-1 Envelope with Potential Use in Microbicides (2012)

Bovine colostrum (first milk) contains very high concentrations of IgG, and on average 1 kg (500 g/liter) of IgG can be harvested from each immunized cow immediately after calving. We used a modified vaccination strategy together with established production systems from the dairy food industry for the large-scale manufacture of broadly neutralizing HIV-1 IgG. This approach provides a low-cost mucosal HIV preventive agent potentially suitable for a topical microbicide. Four cows were vaccinated pre- and/or postconception with recombinant HIV-1 gp140 envelope (Env) oligomers of clade B or A, B, and C. Colostrum and purified colostrum IgG were assessed for cross-clade binding and neutralization against a panel of 27 Env-pseudotyped reporter viruses. Vaccination elicited high anti-gp140 IgG titers in serum and colostrum with reciprocal endpoint titers of up to 1 × 10(5). While nonimmune colostrum showed some intrinsic neutralizing activity, colostrum from 2 cows receiving a longer-duration vaccination regimen demonstrated broad HIV-1-neutralizing activity. Colostrum-purified polyclonal IgG retained gp140 reactivity and neutralization activity and blocked the binding of the b12 monoclonal antibody to gp140, showing specificity for the CD4 binding site. Colostrum-derived anti-HIV antibodies offer a cost-effective option for preparing the substantial quantities of broadly neutralizing antibodies that would be needed in a low-cost topical combination HIV-1 microbicide.
Flicker Compensation for Archived Film Using a Spatially-Adaptive Nonlinear Model (2006)

We present a novel approach for the compensation of temporal brightness variations (commonly referred to as flicker) in archived film sequences. The proposed method is motivated by fundamental principles of photographic image registration and provides a substantial level of adaptation to temporal but also spatial variations of picture brightness. Additionally our scheme provides an efficient mechanism for the appointment and dynamic update of reference frames which makes it suitable for the compensation of long duration film sequences while it addresses problems arising from scene motion using a novel motion-compensated greylevel tracing approach. We present experimental evidence which suggests that our method offers high levels of performance and compares favourably with competing state-of-the-art techniques for flicker compensation
Wechsler Adult Intelligence Scale, 3rd Edition (WAIS-III): Usefulness in the Early Detection of Alzheimer's Disease (2009)

We examined Alzheimer’s disease (AD) patients using a Japanese version of the Wechsler Adult Intelligence Scale, 3rd Edition (JWAIS-III) to clarify i) the significance of expansion of the indicated age range, ii) the characteristics of cognitive impairment in AD patients and iii) the efficacy of th neuropsychological assessment for the early detection of AD using the Digit Symbol subtest, which involves attention and episodic memory, and the Pairing supplementa-ry test, which relates to digit symbol-incidental learning. The JWAIS-III was given to 43 AD patients (12 males and 31 females; mean age, 80.9 ± 6.3 years, who fulfilled the diagnostic cri-teria for AD on the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) and the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer’s Disease and Related Disorders Association. Severity of dementia of the patients was classified according to Functional Assessment Staging (F) as follows: 9 patients in F3 (borderline), 15 in F4 (mild AD), 12 in F5 (moderate AD), 7 in F6 (somewhat severe AD) and none in F7 (severe AD). i) Mean intelligence quotients (IQs) were: Full Scale IQ 84.3 ± 14.0, Verbal IQ 84.6 ± 12.5 and Performance IQ 86.9 ± 15.5. Comparison of IQs and subtest scores of the patients aged 75 years or older assessed by standard scores for 70 to 74 years of age, which is the upper limit of the indicated age range on the WAIS-R (the previous version of the WAIS-III), with those assessed by the standard scores for the appropriate age revealed that the former were significantly lower in IQ and all subtest scores. ii) Significant differ-ences were noted among the severities of dementia in the scores of 7 subtests for Similarities, Comprehension, Arithmetic, Digit Span, Letter-Number Sequencing, Digit Symbol and Sym-bol Search. iii) When both the Digit Symbol subtest scores of 7 points or more and the Digit Sumbol-Pairing supplementary test scores exceeding 10% of the cumulative percentile were regarded as normal, 11 of 15 (73.3%) patients in F4 (mild AD) could be detected. These find-ings suggest that i) expansion of the indicated age range in the WAIS-III allows a more valid assessment of cognitive function in AD patients, ii) a marked decline in abstract thinking and verbal problem-solving ability and relative preservation of Perceptual organization are char-acteristics of cognitive impairment in AD patients and iii) a combination of the Digit Symbol subtest with the Pairing supplementary test is useful for the early detection of AD.
The effect of write head structures on written transitions in perpendicular media (2005)

Write heads with rectangular and crescent-shaped main poles were used for simulations of recording in perpendicular media. Transition curvature was reduced by using a crescent-shaped head, but the lower head-field gradient also reduced the signal-to-noise ratio (SNR). The addition of a trailing shield narrowed the difference in SNR between the two types of heads, whilst the track width was up to 3 nm narrower when written by a crescent-shaped head.
Citrate and calcium effects on Tamm-Horsfall glycoprotein as a modifier of calcium oxalate crystal aggregation (1993)

We measured the effects of Tamm-Horsfall glycoprotein (THP) on calcium oxalate monohydrate (COM) crystal aggregation (Ac) in vitro as well as intrinsic viscosities (Vi) of THP at pH 5.7 and 200 mM NaCl and studied the effects of calcium and citrate on these parameters. THP were isolated from 24-h urines of seven male recurrent calcium stone formers (RCSF) and eight age-matched male healthy volunteers (N, normal). At basal conditions, RCSF-THP inhibited Ac by 28 +/- 10% and normal THP by 60 +/- 6% (P = 0.028). In the presence of calcium, increasing THP concentrations from 16 to 28 and 40 mg/l progressively lowered inhibition by RCSF-THP, but not by N-THP. At 40 mg/l, inhibition by N-THP was 27 +/- 9% vs. -43 +/- 8% by RCSF-THP (P = 0.001), i.e., all stone former THP promoted Ac. With an additional 3.5 mM of citrate, inhibition of Ac was 56 +/- 5% by normal and 34 +/- 6% by stone former THP (P = 0.021), and all seven stone former THP again inhibited Ac. Vi of RCSF-THP was higher than that of N at basal conditions (162 +/- 21 vs. 93 +/- 15 ml/g, P = 0.021) and in the presence of 5 mM calcium (352 +/- 54 vs. 118 +/- 17 ml/g, P = 0.001), i.e., RCSF-THP were more self-aggregated, but not when citrate was added (185 +/- 29 vs. 123 +/- 19 ml/g). (ABSTRACT TRUNCATED AT 250 WORDS)
Cell broadband engine interconnect and memory interface (2005)

Presents a collection of slides covering the following topics: cell broadband engine key features; cell BE interconnect; cell broadband engine die; bus interface controller; element interconnect bus; resource allocation management; memory interface controller; and design to support XDR DRAM controller.
Heat-Treated PtCo<sub>3</sub> Nanoparticles as Oxygen Reduction Catalysts (2009)

PtCo3/C catalysts for oxygen reduction were prepared and heat-treated between 350 and 1000 °C under reductive conditions. The catalysts were activated by cyclic voltammetry, which resulted in the partial oxidative leaching of cobalt. Subsequent rotating disk electrode measurements showed a maximum mass activity for samples tempered at 800 °C, which yielded a 2.4 times higher activity than commercial PtCox/C. TEM images revealed that the particle size of the PtCo3/C catalysts remains almost constant until a temperature of 600 °C is reached; a further temperature increase leads to a noticeable particle growth and a broadening of the particle size distribution. XRD measurements showed that heat treatment leads to the formation of fcc-Pt, Pt3Co, fct-PtCo, fcc-PtCo, and cobalt. The fct- and fcc-PtCo phases are present in samples with the highest catalytic activities.
Single Peptide-Based Protein Identification in Human Proteome through MALDI-TOF MS Coupled with Amino Acids Coded Mass Tagging (2003)

Identification of proteins with low sequence coverage using mass spectrometry (MS) requires tandem MS/MS peptide sequencing. It is very challenging to obtain a complete or to interpret an incomplete tandem MS/MS spectrum from fragmentation of a weak peptide ion signal for sequence assignment. Here, we have developed an effective and high-throughput MALDI-TOF-based method for the identification of membrane and other low-abundance proteins with a simple, one-dimensional separation step. In this approach, several stable isotope-labeled amino acid precursors were selected to mass-tag, in parallel, the human proteome of human skin fibroblast cells in a residue-specific manner during in vivo cell culturing. These labeled residues can be recognized by their characteristic isotope patterns in MALDI-TOF MS spectra. The isotope pattern of particular peptides induced by the different labeled precursors provides information about their amino acid compositions. The specificity of peptide signals in a peptide mass mapping is thus greatly enhanced, resolving a high degree of mass degeneracy of proteolytic peptides derived from the complex human proteome. Further, false positive matches in database searching can be eliminated. More importantly, proteins can be accurately identified through a single peptide with its m/z value and partial amino acid composition. With the increased solubility of hydrophobic proteins in SDS, we have demonstrated that our approach is effective for the identification of membrane and low-abundant proteins with low sequence coverage and weak signal intensity, which are often difficult for obtaining informative fragment patterns in tandem MS/MS peptide sequencing analysis.
남해도 소하천 담수어류 군집에 관한 연구 (2016)

본 연구는 남해도 일대를 흐르는 소하천들을 대상으로 2014년 6월부터 10월까지 조사하여 다음과 같은 결과를 얻었다. 남해도의 23개 소하천의 31개 지점에서 채집된 어류는 모두 13과 30속 38종으로 나타났다. 이 중 잉어과 (Cyprinidae), 망둑어과(Gobiidae) 어류가 각각 11종(28.9%)으로 다른 분류군에 비하여 높은 비율을 차지하였으며, 미꾸리과(Cobitidae) 어류가 4종(10.5%)이 출현하였다. 남해도에서 채집된 전체 어류 중 참갈겨니(Zacco koreanus)의 상대풍부도가 30.3%(1,089개체)로 가장 높은 비율을 보였으며, 한국고유종은 참갈겨니, 긴몰개, 쉬리, 눈동자개, 남방종개, 왕종개, 미유기, 자가사리 등 8종(33.8%)이었고, 외래도입종으로 큰입배스(Micropterus salmoides)가 출현하였다. 종다양도 지수, 균등도 지수 및 종풍부도 지수로 보면 S7에서 비교적 안정적인 어류 군집을 형성하고 있었다. 조사된남해도 소하천들은 하폭, 수심, 하상 구성물질, 하천식생 및 주변의 토지이용도에 따라 산지형, 산지-평지형, 평지형 소하천의 3가지 유형으로 구분되었다. 종별 개체수 자료를 사용하여 요인분석을 실시한 결과, 조사지점은 인간의 인위적 영향 및 토지이용도에 따라 3개의 집단으로 구분되었다. 남해도 소하천의 어류 군집구조는 일차적으로 하상의종적 환경 변화에 의하여 영향을 받고 있으며, 일부 소하천에서는 토지이용도에 따른 서식지 변화에 의하여 어류 군집구조에 영향을 주는 것으로 나타났다.
Initial evaluation of displacement ventilation and dedicated outdoor air systems for U.S. commercial buildings (2005)

Conventional heating, ventilation and air-conditioning (HVAC) systems in commercial buildings meet both outdoor air ventilation and space conditioning requirements using air distribution approaches that provide a mixture of outdoor air and recirculated air with the goal of achieving good air mixing within the occupied space. More recently, advanced ventilation approaches have been proposed, and in some cases installed, that separate the outdoor air ventilation and space conditioning functions (dedicated outdoor air systems or DOAS) or that distribute air to achieve thermal stratification within the space (displacement ventilation or DV). NIST has completed an initial evaluation of the potential benefits and limitations of DV or DOAS in lieu of the conventional mixing ventilation (MV) approach common in U.S. commercial buildings.
A New Chemical Constituent from the Hairy Root Cultures of Catharanthus roseus (2007)

One new compound, 3,7,11,19,23,27-hexamethyl-15-hydroxymethylene-n-octacos-5,8,20-triene-10β,18α- diol-10β-D-glucopyranoside (1), along with the three known compounds, 3-epibetulinic acid (2), n-pentadecanyl octa-dec-19-en-oate (3) and β-sitosterol (4) were isolated from the methanolic extract of the cultured Catharanthus roseus hairy roots. The structures of the one new and three known compounds were elucidated using one- and two-dimensional NMR in combination with IR, EI/MS, FAB/MS. To the best of our knowledge, 3,7,11,19,23,27-hexamethyl-15-hydroxymethylene-n-octacos-5,8,20-triene-10β,18α-diol-10β-D-glucopyranoside, 3-epibetulinic acid and n-pentadecanyl octa-dec-19-en-oate were identified for the first time from the hairy roots of C. roseus.
Promotion of wound healing by yeast glucan evaluated on single animals. (1985)

The effectiveness of yeast glucan in the acceleration of wound healing was evaluated in mice, rats and guinea pigs. In all experiments comparison between glucan treatment in one hind leg and saline treatment as control on the other leg was made on identical wounds. The degree of healing in the two legs was evaluated macroscopically and classified as follows: 1. healing more advanced in glucan treated wound marked by (+). 2. No significant difference between the two legs marked by (0). 3. Healing more advanced in the control wound, marked by (-). During the days when the differences were most obvious, 60% to 80% of the animals showed more advanced healing in the glucan treated wound, 20% to 40% showed no significant difference; and 0 to 15% showed more advanced healing in the control, saline treated wound. The average time for complete wound healing was reduced by about 18% as a result of glucan treatment. The histological analysis shows that the acceleration of wound healing was mediated by early arrival of macrophages to the wound area in the glucan treated wounds.
Layered Neural Networks with Gaussian Hidden Units as Universal Approximations (1990)

A neural network with a single layer of hidden units of gaussian type is proved to be a universal approximator for real-valued maps defined on convex, compact sets of R n .
Characterization of normal human brain cultures. Evidence for the outgrowth of leptomeningeal cells. (1986)

To establish the histogenetic identity of the predominant cell type in monolayer cultures of normal human adult brain, eight brain specimens were placed into culture and characterized according to cell kinetics, karyotype, antigenic expression, and ultrastructural features. The protein profiles of both the cell layer and the medium were analyzed in selected cultures using sodium dodecyl sulfate polyacrylamide gel electrophoresis and diethylaminoethyl cellulose chromatography. All cultures displayed a limited life span in vitro; marked contact inhibition at confluence; a normal karyotype; an intracytoplasmic and extracellular glycoprotein profile consisting of fibronectin, procollagen type III, laminin, and collagen type IV; specialized intercellular junctions; and interstitial collagen chain synthesis. All of these features were identified in our previous study of human leptomeningeal cultures. The results of immunocytochemical staining for glial fibrillary acidic protein were negative in all cultures of normal human brain, except in early passages in two cultures, which lost the glial cell marker during subsequent passages; immunostains for vimentin were positive in all cells in all cultures. These results support the hypothesis that, in this study, cultures derived from normal human brain are not of glial origin. Our findings also suggest that glial cells are less well-suited to monolayer growth under our culture conditions than are other cell types in enzyme-dissociated brain tissue placed in culture, especially leptomeningeal cells. The identification of leptomeningeal cells as the predominant cell type in normal human brain cultures may prove useful in attempts to foster the growth of human glial cells by culturing brain samples under conditions that prohibit the growth of leptomeningeal cells. Under such conditions, astrocytes, oligodendroglia, and ependymal cells could be isolated with greater ease and cultured separately. These purified cultures of different glial cell types would then provide a more relevant in vitro model for studying human neurological diseases.
Combined <i>Bone Morphogenetic Protein-2</i> and <i>−7</i> Gene Transfer Enhances Osteoblastic Differentiation and Spine Fusion in a Rodent Model (2004)

Combined BMP2 and BMP7 gene transfer is significantly more effective in inducing osteoblastic differentiation and spine fusion than individual BMP gene transfer.
Protocol Extension for Support of Asynchronous Transfer Mode (ATM) Service Class-aware Multiprotocol Label Switching (MPLS) Traffic Engineering (2003)

This document specifies a Resource ReSerVation Protocol-Traffic Engineering (RSVP-TE) signaling extension for support of Asynchronous Transfer Mode (ATM) Service Class-aware Multiprotocol Label Switching (MPLS) Traffic Engineering.
Validating IP Prefixes and AS-Paths with Blockchains (2019)

Networks (Autonomous Systems-AS) allocate or revoke IP prefixes with the intervention of official Internet resource number authorities, and select and advertise policy-compliant paths towards these prefixes using the inter-domain routing system and its primary enabler, the Border Gateway Protocol (BGP). Securing BGP has been a long-term objective of several research and industrial efforts during the last decades, that have culminated in the Resource Public Key Infrastructure (RPKI) for the cryptographic verification of prefix-to-AS assignments. However, there is still no widely adopted solution for securing IP prefixes and the (AS-)paths leading to them; approaches such as BGPsec have seen minuscule deployment. In this work, we design and implement a Blockchain-based system that (i) can be used to validate both of these resource types, (ii) can work passively and does not require any changes in the inter-domain routing system (BGP, RPKI), and (iii) can be combined with currently available systems for the detection and mitigation of routing attacks. We present early results and insights w.r.t. scalability.
Incorporation of Small Molecular Weight Active Agents into Polymeric Components (2008)

The incorporation of small molecular weight active agents into polymeric matrixes bearing controlled release characteristics represents an interesting strategy with numerous useful applications. Antimicrobials, biocides, fungicides or drugs, encapsulated into erodible or non-erodible polymeric micro-spheres, micro-capsules and micro-shells or/and embedded into continuous polymeric matrixes, are controlled released either by particular degradation routes or/and by specific stimuli. Cross-linking, curing or micro-porosity generating agents acting during polymerization impart additional controlled encapsulation characteristics to the active substances. Release modulating agents, like retardants or carrier materials used as vehicles are often encapsulated into microspheres or dispersed within polymeric compositions for the controlled introduction of an active agent into a liquid-based medium. The aim of this review is to reveal relevant strategies reported in recent patents on the encapsulation or incorporation of low molecular weight active agents into the matrix of polymers bearing controlled release characteristics. The inventions described implicate the formation of both erodible and non erodible polymer microparticles that contain active ingredients. Modification of polymer matrix and inorganic porous carriers represent pertinent major strategies that have been also developed and patented.
66 MHz 2.3 M ternary dynamic content addressable memory (2002)

This paper describes a 66 MHz 2.3 M Content Addressable Memory (CAM) which uses DRAM technology for the basic ternary CAM cell. The chip's architecture allows a high speed search operation and single cycle learning. The DRAM based cell structure enables implementation of a larger table size than is available in similar technology SRAM based CAMs. A new matchline sense amplifier allows fast, low power sensing of the matchline. Among the chip's many features are a DDR input interface and the ability to cascade up to eight parts without additional logic. The density and speed of this part make it suitable for many applications such as network switching.
Electromechanical modelling of overhead cranes (1992)

Abstract A non-linear electromechanical model describing the dynamical behaviour of overhead cranes is presented. The model takes into consideration the non-linear dependence of the load sway on transients of driving motors during voltage disturbances and start-ups. This is extremely useful in practice since load sway control schemes normally utilize input voltages as control variables. The mechanical subsystem within the model is that of the load sway and has the swing angles and their derivatives as state variables. Each of the two driving motors, namely, the girder motor and the trolley motor, is represented by the classical fifth-order model of induction machines where electrical transients as well as mechanical transients are considered. The model is linearized using Taylor series expansion around a normal operating point. A numerical example is presented to illustrate the usefulness of the results.