gebhart/patrepeval huggingface dataset:
Magneto-Structural Effects of the Jahn-Teller Distortions on 2,2'-Bipyrimidine-, (bpm-) Bridged Dinuclear Copper(II) Complexes: Crystal Structures and Magnetic Properties of [Cu2(bpm)(H2O)4(SO4)2].cntdot.3H2O and [Cu2(bpm)(H2O)8](SO4)2.cntdot.2H2O (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMagneto-Structural Effects of the Jahn-Teller Distortions on 2,2'-Bipyrimidine-, (bpm-) Bridged Dinuclear Copper(II) Complexes: Crystal Structures and Magnetic Properties of [Cu2(bpm)(H2O)4(SO4)2].cntdot.3H2O and [Cu2(bpm)(H2O)8](SO4)2.cntdot.2H2OGiovanni De Munno, Miguel Julve, Francesc Lloret, Juan Cano, and Andrea CaneschiCite this: Inorg. Chem. 1995, 34, 8, 2048–2053Publication Date (Print):April 1, 1995Publication History Published online1 May 2002Published inissue 1 April 1995https://pubs.acs.org/doi/10.1021/ic00112a016https://doi.org/10.1021/ic00112a016research-articleACS PublicationsRequest reuse permissionsArticle Views215Altmetric-Citations50LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Nucleotide sequences important for translation initiation of enterovirus RNA (1991)

An infectious cDNA clone was constructed from the genome of coxsackievirus B1 strain. A number of RNA transcripts that have mutations in the 5' noncoding region were synthesized in vitro from the modified cDNA clones and examined for their abilities to act as mRNAs in a cell-free translation system prepared from HeLa S3 cells. RNAs that lack nucleotide sequences at positions 568 to 726 and 565 to 726 were found to be less efficient and inactive mRNAs, respectively. To understand the biological significance of this region of RNA, small deletions and point mutations were introduced in the nucleotide sequence between positions 538 and 601. Except for a nucleotide substitution at 592 (U----C) within the 7-base conserved sequence, mutations introduced in the sequence downstream of position 568 did not affect much, if any, of the ability of RNA to act as mRNA. Except for a point mutation at 558 (C----U), mutations upstream of position 567 appeared to inactivate the mRNA. In the upstream region, a sequence consisting of 21 nucleotides at positions 546 to 566 is perfectly conserved in the 5' noncoding regions of enterovirus and rhinovirus genomes. These results suggest that the 7-base conserved sequence functions to maintain the efficiency of translation initiation and that the nucleotide sequence upstream of position 567, including the 21-base conserved sequence, plays essential roles in translation initiation. A deletion mutant whose genome lacks the nucleotide sequence at positions 568 to 726 showed a small-plaque phenotype and less virulence against suckling mice than the wild-type virus. Thus, reduction of the efficiency of translation initiation may result in the construction of enteroviruses with the lower-virulence phenotype.
Substrate elasticity affects bovine satellite cell activation kinetics in vitro (2013)

Satellite cells support efficient postnatal skeletal muscle hypertrophy through fusion into the adjacent muscle fiber. Nuclear contribution allows for maintenance of the fiber myonuclear domain and proficient transcription of myogenic genes. Niche growth factors affect satellite cell biology; however, the interplay between fiber elasticity and microenvironment proteins remains largely unknown. The objective of the experiment was to examine the effects of hepatocyte growth factor (HGF) and surface elasticity on bovine satellite cell (BSC) activation kinetics in vitro. Young's elastic modulus was calculated for the semimembranosus (SM) and LM muscles of young bulls (5 d; n = 8) and adult cows (27 mo; n = 4) cattle. Results indicate that LM elasticity decreased (P < 0.05) with age; no difference in Young's modulus for the SM was noted. Bovine satellite cells were seeded atop polyacrylamide bioscaffolds with surface elasticities that mimic young bull and adult cow LM or traditional cultureware. Cells were maintained in low-serum media supplemented with 5 ng/mL HGF or vehicle only for 24 or 48 h. Activation was evaluated by proliferating cell nuclear antigen (PCNA) immunocytochemistry. Results indicate that BSC maintained on rigid surfaces were activated at 24 h and refractive to HGF supplementation. By contrast, fewer (P < 0.05) BSC had exited quiescence after 24 h of culture on surfaces reflective of either young bull (8.1 ± 1.7 kPa) or adult cow (14.6 ± 1.6 kPa) LM. Supplementation with HGF promoted activation of BSC cultured on bioscaffolds as measured by an increase (P < 0.05) in PCNA immunopositive cells. Culture on pliant surfaces affected neither activation kinetics nor numbers of Paired box 7 (Pax7) immunopositive muscle stem cells (P > 0.05). However, with increasing surface elasticity, an increase (P < 0.05) in the numbers of muscle progenitors was observed. These results confirm that biophysical and biochemical signals regulate BSC activation.
Analysis of β-Lactam Antibiotics in Incurred Raw Milk by Rapid Test Methods and Liquid Chromatography Coupled with Electrospray Ionization Tandem Mass Spectrometry (2001)

A recently developed confirmatory LC-MS method has been applied to the quantification of five major beta-lactam antibiotics in suspect raw bovine milk samples that gave a positive response with receptor-based (BetaStar) and rapid microbial inhibitory screen tests (Delvotest SP). In total, 18 presumptive positive raw milk samples were reanalyzed; 16 samples showed traces of antibiotic residues that could be identified and quantified by the LC-MS method, ranging from the limits of confirmation up to 38 microg/kg. Of the positive samples, only five (approximately 30%) were found to be violative of EU maximum residue limits. The most frequently detected antibiotic residues were cloxacillin and penicillin G, the former often in combination with amoxicillin or ampicillin. This study compares the results obtained by the three methods on identical samples and addresses how these relate to certain criteria such as sensitivity and selectivity. Furthermore, the limitations of the LC-MS method and the potential impact of the presence of frequently more than one residue in the same milk sample on the response of the rapid test methods are discussed.
Low Temperature Cofired Ceramic Microfluidic Microsystems for High Temperature and High Pressure Applications (2006)

As an alternative material to glass, silicon, and plastics, Low Temperature Cofired Ceramic (LTCC) substrate technology is becoming increasingly important for enabling microfluidic microsystems and devices for integrated chemical and biological analysis. LTCC's simple fabrication method and unique ability to withstand high temperatures and high pressures make it well-suited for applications not possible with traditional materials. As part of Sandia's initiative to develop an automated sample preparation system for the μChemlab™ bioagent detector, an integrated microfluidic lyser using LTCC technology has been fabricated, which enables the use of aqueous buffers at high temperatures without boiling by using a pressurized system. Thermal lysing of bacterial spores in a flow-through microfluidic device at temperatures as high as 220°C and pressures up to 10.3 MPa (1,500 psi) represents a new method for solubilizing spore proteins for identification and analysis, eliminating the reliance on harsh chemical reducing agents for lysing. This paper will present results on the development of a microfluidic LTCC-based lyser by taking advantage of the inherent properties of LTCC substrates. Specifically, the performance and implementation of a prototype LTCC lyser for solubilizing bacterial spore proteins will be reported.
Low-temperature bonding of silicon-oxide-covered wafers using diluted HF etching (2004)

For bonded pairs of silicon-oxide-covered wafers, the bonding energy at low temperatures is significantly enhanced by very slight etching of the silicon oxide surfaces in diluted (0.05%–0.2%) HF aqueous solutions prior to room temperature contacting. The bonding energy is a factor of 10 higher than standard bonded pairs to about 2000mJ∕m2 after annealing at 100°C. The improved surface cleaning and activation with desired surface termination have been achieved by the HF dip. A fluorine concentration peak at the bonding interface measured by secondary ion mass spectroscopy suggests that the number of Si–O–Si covalent bonds at the bonding interface appears to be increased appreciably by the formation of fluorinated silicon oxide that absorbs water effectively.
Highly Stretchable and Wearable Graphene Strain Sensors with Controllable Sensitivity for Human Motion Monitoring (2015)

Because of their outstanding electrical and mechanical properties, graphene strain sensors have attracted extensive attention for electronic applications in virtual reality, robotics, medical diagnostics, and healthcare. Although several strain sensors based on graphene have been reported, the stretchability and sensitivity of these sensors remain limited, and also there is a pressing need to develop a practical fabrication process. This paper reports the fabrication and characterization of new types of graphene strain sensors based on stretchable yarns. Highly stretchable, sensitive, and wearable sensors are realized by a layer-by-layer assembly method that is simple, low-cost, scalable, and solution-processable. Because of the yarn structures, these sensors exhibit high stretchability (up to 150%) and versatility, and can detect both large- and small-scale human motions. For this study, wearable electronics are fabricated with implanted sensors that can monitor diverse human motions, including joint movement, phonation, swallowing, and breathing.
Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein (2003)

Expression of misfolded protein in cultured cells frequently leads to the formation of juxtanuclear inclusions that have been termed 'aggresomes'. Aggresome formation is an active cellular response that involves trafficking of the offending protein along microtubules, reorganization of intermediate filaments and recruitment of components of the ubiquitin proteasome system. Whether aggresomes are benevolent or noxious is unknown, but they are of particular interest because of the appearance of similar inclusions in protein deposition diseases. Here we present evidence that aggresomes serve a cytoprotective function and are associated with accelerated turnover of mutant proteins. We show that mutant androgen receptor (AR), the protein responsible for X-linked spinobulbar muscular atrophy, forms insoluble aggregates and is toxic to cultured cells. Mutant AR was also found to form aggresomes in a process distinct from aggregation. Molecular and pharmacological interventions were used to disrupt aggresome formation, revealing their cytoprotective function. Aggresome-forming proteins were found to have an accelerated rate of turnover, and this turnover was slowed by inhibition of aggresome formation. Finally, we show that aggresome-forming proteins become membrane-bound and associate with lysosomal structures. Together, these findings suggest that aggresomes are cytoprotective, serving as cytoplasmic recruitment centers to facilitate degradation of toxic proteins.
Norovirus Outbreaks from Drinking Water (2005)

As part of an intensified monitoring program for foodborne disease outbreaks in Finland, waterborne outbreaks were investigated for viruses. The diagnostic procedure included analysis of patients' stool samples by electron microscopy and reverse transcription-polymerase chain reaction (RT-PCR) for noroviruses and astroviruses. When these test results were positive for a virus, the water sample was analyzed. Virus concentration was based on positively charged filters from 1-L samples. Of the total 41 waterborne outbreaks reported during the observation period (1998-2003), samples from 28 outbreaks were available for analysis. As judged by RT-PCR results from patient samples, noroviruses caused 18 outbreaks. In 10 outbreaks, the water sample also yielded a norovirus. In all but 1 instance, the amplicon sequence was identical to that recovered from the patients. The ubiquity of waterborne norovirus outbreaks calls for measures to monitor water for viruses.
Block-overlap transform coding of image signals (1984)

A novel feature-based method, which is scale invariant feature transform (SIFT) and RANdom SAmple Consensus (RANSAC) integration algorithm, is introduced to promote the automated identification of the breech face impression, the most common mark left on the cartridge used for firearm evidence. SIFT algorithm is employed to extract the local extrema from examined impression as keypoints representing its invariant features, and to build the feature descriptor for each keypoint based on its local gradients in neighborhood. RANSAC is used to improve the matching performance among these keypoints and feature descriptors. With hypothesize-and-verify methods, RANSAC is able to construct the best model fitting initial matching pairs of keypoints and to guarantee the robust comparison result. Validation tests using 40 cartridge cases fired from pistols with 10 consecutively manufactured slides yielded a clear separation result, which strongly supports the effectiveness of the ensemble algorithm of SIFT and RANSAC. This application indicates the practical feasibility of feature-based algorithm and image processing technique in forensic science.
Relationship Between Cognition and Functional Outcomes After Dysvascular Lower Extremity Amputation (2014)

These findings highlight the potential value in including a brief, formal cognitive assessment in addition to a general mental status screen. Specific domains of cognitive function are differentially associated with functional outcomes and may inform amputation rehabilitation decisions.
Diisothiocyanatophosphonitrilic Chloride Trimer and its Derivatives (1972)

Abstract Diisothiocyanatophosphonitrilic chloride trimer has been prepared by the reaction of a stoichiometric quantity of ammonium thiocyanate with phosphonitrilic chloride trimer in acetone. Alcohol and amine derivatives of this compound have been prepared by addition reactions.
Fama Architecture: Implementation Details (1987)

The FAMA (Fine granularity Advanced Multiprocessor Architecture), currently being developed in the Department of Electrical Engineering and Computer Science of the University of Zaragoza, is an SIMD array architecture optimized for computer-vision applications. Because of its high cost-effectiveness, it is a very interesting alternative for industrial systems. Papers describing the processor element of FAMA have been submitted to several conferences; this paper focuses on the rest of components that complete the architecture: controller, I/O interface and software. The controller generates instructions at a 10MHz rate, allowing efficient access to bidimensional data structures. The I/O interface is capable of reordering information for efficient I/O operations. Development tools and modules for classical computer-vision tasks are being worked on in a first stage, the implementation of models based on existing theories on human vision will follow.
An incremental algorithm for mining classification rules in incomplete information systems (2004)

One of important research areas in data mining is to develop methods to update knowledge by using the existing knowledge, since it can generally enhance mining efficiency, especially for very large database. Rough set, a new mathematical tool to deal with vagueness and uncertainty, has been successfully applied in data mining. Presently, several approaches based on rough set have been proposed for mining tasks when knowledge updates. However, it only aims at complete information systems. In fact, many information systems are incomplete in practical application. Therefore, in order to support more effective data mining tasks, it is meaningful to develop approaches to update knowledge in incomplete information systems (US). A method for incremental updating approximations of a concept was proposed by T. R. Li, et al (2003), which may realize adding and deleting a few attributes simultaneously at a time. Based on this method, we develop an incremental algorithm for mining classification rules from IIS. Complexity analysis of the algorithm and example show that our method can realize updating knowledge effectively.
The Role of IRE1 Signaling in the Central Nervous System Diseases (2018)

The accumulation of misfolded or unfolded proteins in endoplasmic reticulum (ER) lumen results in the activation of an adaptive stress process called the unfolded protein response (UPR). As the most conserved signaling branch of the UPR, Inositol-requiring enzyme 1 (IRE1) possesses both Ser/Thr kinase and RNase activities operating as major stress sensors, mediating both adaptive and pro-apoptotic pathways under ER stress. Over the last three decades, a mounting body of evidence has shown that IRE1 signaling dysfunction is involved in the pathology of various neurological disorders. Targeting this pathway has emerged as a promising therapeutic strategy against these diseases. In this review, we provide a general overview about the expression and physiological function of IRE1 signaling and its pathophysiological roles in the central nervous system diseases.
A wearable computer for use in microgravity space and other non-desktop environments (1996)

We present one possible design for a “wearable” computer—a computer that is worn. Our prototype permits text entry without the need of a table or other supporting surface. Typing can be performed while standing or even walking, Possible applications for this device are also discussed.
Modulating macrophage function with IgG immune complexes (2002)

Macrophages respond to bacterial products by releasing a large array of inflammatory mediators. We demonstrate that, in the presence of IgG immune complexes, macrophages produce high levels of IL-10 and virtually no IL-12, when they are exposed to bacterial products. The production of IL-10 by these cells can dampen innate inflammatory responses to microbial products, such as LPS. This alteration in macrophage cytokine production can also influence an adaptive immune response, preferentially inducing Th2-type immunity. Thus, immune complexes change the physiology of activated macrophages, converting them to anti-inflammatory cells that induce Th2-like immune responses. We have termed these cells type II activated macrophages.
Memory Intensive Architectures for DSP and Data Communication (2002)

We focus on the design of systems where memory performance is the principal bottleneck. Two kinds of systems have been considered, an FFT engine for use in high performance DSP systems and forwarding engines used in high-speed routers. \n\nThe FFT engine was designed using Seamless High Off-Chip Connectivity (SHOCC), a high-density interconnect and packaging technology. The SHOCC substrate was analyzed for different substrate stack-ups to determine the I/O bandwidth attainable by the technology. The FFT engine was designed to make full use of this available bandwidth. It provides for rotation of data to maintain a constant stride between stages, ensuring a constant data access pattern between different stages of the FFT. Data is twiddled before storing in memory, and an efficient scheduling algorithm allows generation of twiddle factors on-chip in parallel with other operations. The memory controller uses a novel memory-mapping scheme to avoid precharge and refresh penalties in DRAMs and achieves SRAM-like access speeds.\n\nForwarding engines in IP routers need to perform a longest-matching-prefix search on the routing database. Two types of forwarding schemes are presented, a hardware-implementable trie based scheme and software implementations of modified binary searches. The hardware trie-based scheme uses a small amount of on-chip SRAM along with an off-chip DRAM (which stores the complete forwarding table). Only a single DRAM access is required to determine the next hop address. The binary search schemes store an additional field in the forwarding database to avoid any backtracking while searching for prefixes.
Measurement Principles of the Reactive Current RMS Value and the Load Susceptance for Harmonic Frequency Meters (1985)

The current of a nonsinusoidal source applied to a nonresistive load contains a reactive component ir which can be decreased or even wholly compensated by a shunt reactance 1-port of parameters related directly to the load susceptances for harmonic frequencies Bn· The reactive current rms value measurement is necessary for evaluation of the possibility of the source apparent power minimization, and the load susceptance measurement is necessary for the compensating equipment design. This paper presents the measurement principles for measuring these quantities.
CARDIOVASCULAR ADAPTATIONS TO TRAINING IN PATIENTS SEROPOSI-TIVE FOR HUMAN IMMUNODEFICIENCY VIKUS (HIV) (1992)

Total Rehabilitation & Athletic Conditioning Center, Novi, MI; Medical College of Ohio, Depts of Medicine and Morse Physical Health Research Center, Toledo, OH.
Generative and 'Ground-Up' Research in Aboriginal Australia (2013)

\n \t\t\tHow might we go about collaborative research that doesn&rsquo;t simply come up with a report or a published paper, but results in changed practices in the areas of our concern? How do we envision and implement a generative methodology in front line research? Working with theory from the academic and Aboriginal worlds, I present examples of research with peopleworking at the front line in various contexts, and reflect upon the role of the researcher in these areas of engagement.\n
Genome-Wide Survey of Transcription Factors in Prokaryotes Reveals Many Bacteria-Specific Families Not Found in Archaea (2006)

Assignment of all transcription factors (TFs) from genome sequence data is not a straightforward task due to the wide variation in TFs among different species. A DNA binding domain (DBD) and a contiguous non-DBD with a characteristic SCOP or Pfam domain combination are observed in most members of TF families. We found that most of the experimentally verified TFs in prokaryotes are detectable by a combination of SCOP or Pfam domains assigned to DBDs and non-DBDs. Based on this finding, we set up rules to detect TFs and classify them into 52 TF families. Application of the rules to 154 entirely sequenced prokaryotic genomes detected >18,000 TFs classified into families, which have been made publicly available from the 'GTOP_TF' database. Despite the rough proportionality of the number of TFs per genome with genome size, species with reduced genomes, i.e. obligatory parasites and symbionts, have only a few if any TFs, reflecting a nearly complete loss. Also the number of TFs is significantly lower in archaea than in bacteria. In addition, all but 1 of the 19 TF families present in archaea is present in bacteria, whereas 33 TF families are found exclusively in bacteria. This observation indicates that a number of new TF families have evolved in bacteria, making the transcription regulatory system more divergent in bacteria than in archaea.