gebhart/patrepeval huggingface dataset:
The bulk index join: a generic approach to processing non-equijoins (1999)

Presents a new algorithm called the 'bulk index join' that can be applied to a broad class of non-equijoins. Similar to the well-known index nested-loops join algorithm, the bulk index join probes the records of the outer relation against the inner relation by using a pre-existing index structure. Like the index nested-loops join, our algorithm is generic in that any tree-based index structure supporting the join predicate can be used. Moreover, the designer of a new index structure might use our generic code to extend the functionality of the index structure without any additional effort. Our experience indicates that the bulk index join is a generic algorithm that performs very fast, and that its implementation is simple enough to be of immediate practical value.
Relationship between Radiation Induced Activation of DNA Repair Genes andRadiation Induced Apoptosis in Human Cell Line A431 (2000)

Purpose: The purpose of this study was to evaluate the relationship between radiation-induced activation of DNA repair genes and radiation induced apoptosis in A431 cell line. Materials and Methods: Five and 25 Gys of gamma radiation were given to A431 cells by a Cs-137 cell irradiator. Apoptosis was evaluated by flow cytometry using annexin V-fluorescein isothiocyanate and propidium iodide staining. The expression of DNA repair genes was evaluated by both Northern and Western blot analyses. Results: The number of apoptotic cells increased with the increased radiation dose. It increased most significantly at 12 hours after irradiation. Expression of p53, p21, and hRAD50 reached the highest level at 12 hours after 5 Gy irradiation. In response to 25 Gy irradiation, hRAD50 and p21 were expressed maximally at 12 hours, but p53 and GADD45 genes showed the highest expression level after 12 hours. Conclusion: Induction of apoptosis and DNA repair by ionizing radiation were closely correlated. The peak time of inducing apoptosis and DNA repair was 12 hours in this study model. hRAD50, a recently discovered DNA repair gene, was also associated with radiation-induced apoptosis.
Advanced Thermoelectric Materials in Electrical and Electronic Applications (2013)

Thermoelectric materials are a novel class of materials having unique characteristics. They are Seebeck and Peltier effect materials and are used as thermocouples, for thermoelectric cooling of microelectronic products, as thermoelectric converter for energy conservation etc. Due to their versatility of behaviour, they are now used as construction materials for microelectronic equipment, wireless sensors also. This paper aims at elaborating the development of such materials by compiling the recent and ongoing researches. In this regard, the research developments of some newer materials by other investigators have been presented here. Brief details of the development of thermoelectric generation, thermoelectric cooling, thermoelectric power generator for wearable systems, nano-thermocouple, thermoelectric Peltier microcoolers etc. are presented. In these elaborations, it is shown by the respective investigators that these TE materials can be effectively used in heavily doped semiconductor, thin films, quantum well etc.
Synthesis and Activity against Multidrug Resistance in Chinese Hamster Ovary Cells of New Acridone-4-carboxamides (1995)

A number of tricyclic carboxamides have been synthesized and tested to evaluate their ability to reverse multidrug resistance in the CHRC/5 cell line. Among them the acridone derivatives were the most potent. A key feature is the presence of a dimethoxybenzyl or phenethylamine cationic site, separated from the tricyclic lipophilic part by a carbamoylphenyl chain. Optimization led to compounds 2 orders of magnitude more active than the prototype inhibitors verapamil and amiodarone. On the basis of in vitro and in vivo activities, 9,10-dihydro-5-methoxy-9-oxo-N-[4-[2-(1,2,3,4-tetrahydro-6,7- dimethoxyisoquinol-2-yl)ethyl]phenyl]-4-acridinecarboxamide (84) has been selected for further development.
Genetic diversity and relationships in populations of Bordetella spp (1986)

Genetic diversity in 60 strains of three nominal Bordetella species recovered from humans and other mammalian hosts was assessed by analyzing electrophoretically demonstrable allelic variation at structural genes encoding 15 enzymes. Eleven of the loci were polymorphic, and 14 distinctive electrophoretic types, representing multilocus genotypes, were identified. The population structure of Bordetella spp. is clonal, and genetic diversity is relatively limited compared with most other pathogenic bacteria and is insufficient to justify recognition of three species. All isolates of Bordetella parapertussis were of one electrophoretic type, which was closely similar to 9 of the 10 electrophoretic types represented by isolates of Bordetella bronchiseptica. Bordetella pertussis 18-323, which is used in mouse potency tests of vaccines, is more similar genetically to isolates of B. bronchiseptica and B. parapertussis than to other isolates currently assigned to the species B. pertussis. Apart from strain 18-323, the isolates of B. pertussis represented only two closely related clones, and all isolates of B. pertussis from North America (except strain 18-323) were genotypically identical. Strain Dejong, which has been classified as B. bronchiseptica, was strongly differentiated from all of the other Bordetella isolates examined.
Human-centric analysis of driver inattention (2013)

Driver distraction is an important risk factor for road traffic injuries, and has been the focus of a number of empirical studies aiming to raise awareness about the risks of distracted driving and to promote countermeasures. While some of the recorded road incidents in these studies have their roots in distracting events (such as mobile phone usage) a large proportion of recorded road incidents can be attributed to more elusive driver inattention factors not linked to specific trigger events. These distraction categories are especially challenging and currently not in focus of current research as they are difficult to detect and address by suitable prognostic measures, in order to improve road safety. To contribute to this issue, this paper presents research into monitoring drivers' mental states in real-time, using objective measurements. We propose an iterative research methodology where specific mental states are elicited, user response captured experimentally, and interaction models built using advanced machine learning techniques. Behavioral measures such as speech, eye activity or posture, and physiological measures such as galvanic skin response or heart rate provide input features for the models. This driver-centric approach addresses the complex issue of driver inattention, and can help improve road safety through active monitoring of road users, customized decision support in the vehicle, and objective training feedback. Low-fidelity simulators we have built allowed us to roll out some preliminary tasks prompting encouraging feedback from subjects during informal testing.
Functionalized Hydrophobic Poly(glycerol-<i>co</i>-ε-caprolactone) Depots for Controlled Drug Release (2012)

A limitation to many polymer-based drug delivery systems is the lack of ability to customize a particular polymer composition for tailoring drug release kinetics to a specific clinical application. In this study, we investigated the structure-property effects of conjugating various hydrophobic biocompatible side chains to poly(glycerol-co-caprolactone) copolymers with the goal of achieving prolonged and controlled release of a chemotherapeutic agent. The choice of side chain significantly affected the resulting polymer properties including thermal transitions, relative crystallinity (ΔH(f)), and hydrophobicity. Drug-loaded films cast from solutions of polymer and 10-hydroxycamptothecin demonstrated prolonged release from four to over seven weeks depending upon side chain structure without initial burst release behavior. Use of the stearic acid-conjugated poly(glycerol-co-caprolactone) films afforded substantial anticancer activity in vitro for at least 50 days when exposed to fresh cultures of A549 human lung cancer cells over 24 h intervals, correlating well with the measured drug release kinetics.
The Spectrum of Rhabdomyolysis (1982)

From the Departments of Medicine, Denver General Hospital, University Hospital, and Veterans Administration Medical Center, Denver, Colorado
Carbon Formation in Catalytic Cracking (1945)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCarbon Formation in Catalytic CrackingAlexis Voorhies JrCite this: Ind. Eng. Chem. 1945, 37, 4, 318–322Publication Date (Print):April 1, 1945Publication History Published online1 May 2002Published inissue 1 April 1945https://pubs.acs.org/doi/10.1021/ie50424a010https://doi.org/10.1021/ie50424a010research-articleACS PublicationsRequest reuse permissionsArticle Views1266Altmetric-Citations262LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
A single-chip 16-bit 25 ns realtime video/image signal processor (2003)

A single-chip real-time video/image processor (VISP) has been developed that integrates functions based on a variable seven-stage pipeline arithmetic architecture in a 16-bit fixed-point data format. A three-input adder implemented in complementary CMOS reduced-swing logic, which is twice as fast as conventional CMOS logic, achieving a 25-ns instruction cycle, is shown. Single-VISP processing times are: edge detection (3*3 Laplacian), 14.8 ms; distance calculation, 1.7 ms; temporal filtering (1-tap IR), 5.0 ms; linear quantization, 3.3 ms; and 3/5*3/5 picture reduction (separate 5-tap FIR), 5.9 ms. An example is shown of a two-dimensional discrete cosine transformation which requires 26.3 ms to execute with one VISP when 256*256 pixel processing at a 25-ns instruction cycle is employed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Formation and characterization of polymersomes made by a solvent injection method (2007)

Abstract In this article a solvent injection method is described for vesicle formation using poly(butadiene)‐ b‐poly(acrylic acid) diblock copolymers as the amphiphilic molecules. Vesicles composed of polymer bilayers are commonly referred to as polymersomes. Solvent injection is shown to be a rapid method for polymersome formation suitable to make large volumes of polymersome solution. The method can be manipulated to obtain a wide range of vesicle sizes depending on the polymer concentration and preparation conditions. Polymersome solutions in this study are characterized using dynamic light scattering (DLS), fluorescent microscopy, and electron microscopy. Polymersome sizes range from tens of nanometers to several microns. The membrane thickness of smaller polymersomes is found to lie between 14–20 nm. Larger polymersomes are found to have somewhat thicker membranes. The procedure involves the addition of polymers dissolved in an organic solvent to a stirred aqueous solution. The formation of polymersomes by this method is proposed to be governed by the limited mutual solubility of the two solvents and the simultaneous diffusion of solvent and water out of and in to initially formed organic solvent droplets. Copyright © 2007 John Wiley & Sons, Ltd.
Image-based planning and validation of C1-C2 transarticular screw fixation using personalized drill guides (2002)

The preoperative planning system allowed the neurosurgeon to rehearse screw insertion in a way that is closer to surgical reality. The image-based validation technique allowed verification and enhancement of the template design on a cadaver study, giving accuracies comparable to those obtained with transfer by navigation.
Oxidant stress regulation of IL-8 and ICAM-1 gene expression: differential activation and binding of the transcription factors AP-1 and NF-kappaB (Review). (1999)

Reactive oxygen species (ROS), generated either extracellularly or intracellularly through ligand-receptor interactions, can function as signal transduction molecules to activate the chemotactic cytokine interleukin-8 (IL-8) and the cell surface adhesion protein, intercellular adhesion molecule-1 (ICAM-1; CD54). Together, IL-8 and ICAM-1 orchestrate the transendothelial migration of neutrophils to sites of inflammation and injury. Recent results demonstrate that oxidant stress generated directly by exogenous H2O2 differentially induce IL-8 and ICAM-1 transcription in epithelial and endothelial cells. H2O2 induces IL-8 but not ICAM-1 in the A549 type-II-like epithelial cell line, whereas in a microvessel endothelial cell line (HMEC-1) as well as in primary endothelial cells, H2O2 induces ICAM-1 but not IL-8, which is spontaneously expressed. In contrast, the pro-inflammatory cytokine TNFalpha, whose activity is dependent on the generation of intracellular ROS, induces IL-8 and ICAM-1 in both cell types. The differential induction of IL-8 and ICAM-1 by H2O2 and TNFalpha suggest that the two inflammatory stimuli target distinct redox responsive signaling pathways to activate cell type-specific gene expression. In this regard, we found that the cell type-specific pattern of IL-8 and ICAM-1 gene expression was associated with the differential activation and promoter binding of the redox regulated transcription factors AP-1 and NF-kappaB. In this review, our current understanding of the redox regulation of the IL-8 and ICAM-1 genes is summarized, and the differential roles AP-1 and NF-kappaB play in their cell type-specific expression, with particular emphasis on the differential effects induced by TNFalpha and H2O2 is discussed.
Photogenerated Excitons in Plain Core CdSe Nanocrystals with Unity Radiative Decay in Single Channel: The Effects of Surface and Ligands (2015)

A systematic and reproducible method was developed to study the decay dynamics of an exciton, a photogenerated electron-hole pair, in semiconductor nanocrystals in solution. Results revealed that the excitons in plain core CdSe nanocrystals in either zinc-blende or wurtzite or mixed lattice structures could be reproducibly prepared to decay radiatively in unity quantum yield and in single channel. The single-channel lifetime was found to increase monotonically by increasing size of the CdSe nanocrystals, with zinc-blende ones increasing in a relatively slow pace. Surface inorganic stoichiometry was found to be a sensitive parameter to affect the exciton decay dynamics for all crystal structures with different sizes. Excess Se (Cd) sites on the surface were found to induce short (long) lifetime channels for the excitons. Both types of traps reduced the quantum yield of the radiative decay of the excitons, and the hole traps associated with Se sites were nearly not emissive. With optimal surface inorganic stoichiometry, primary amines were identified as "ideal" organic ligands for CdSe core nanocrystals to achieve unity radiative decay of excitons in single channel in comparison to other types of neutral ligands commonly applied in the field.
Microfibrillar network of a rigid rod polymer. 1. Visualization by electron microscopy (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMicrofibrillar network of a rigid rod polymer. 1. Visualization by electron microscopyYachin Cohen and Edwin L. ThomasCite this: Macromolecules 1988, 21, 2, 433–435Publication Date (Print):February 1, 1988Publication History Published online1 May 2002Published inissue 1 February 1988https://doi.org/10.1021/ma00180a025RIGHTS & PERMISSIONSArticle Views227Altmetric-Citations55LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alertsclose Get e-Alerts
Basic fibroblast growth factor accelerates and improves second‐degree burn wound healing (2008)

Second-degree burns are sometimes a concern for shortening patient suffering time as well as the therapeutic choice. Thus, adult second-degree burn patients (average 57.8 +/- 13.9 years old), mainly with deep dermal burns, were included. Patients receiving topical basic fibroblast growth factor (bFGF) or no bFGF were compared for clinical scar extent, passive scar hardness and elasticity using a Cutometer, direct scar hardness using a durometer, and moisture analysis of the stratum corneum at 1 year after complete wound healing. There was significantly faster wound healing with bFGF, as early as 2.2 +/- 0.9 days from the burn injury, compared with non-bFGF use (12.0 +/- 2.2 vs. 15.0 +/- 2.7 days, p<0.01). Clinical evaluation of Vancouver scale scores showed significant differences between bFGF-treated and non-bFGF-treated scars (p<0.01). Both maximal scar extension and the ratio of scar retraction to maximal scar extension, elasticity, by Cutometer were significantly greater in bFGF-treated scars than non-bFGF-treated scars (0.23 +/- 0.10 vs. 0.14 +/- 0.06 mm, 0.59 +/- 0.20 vs. 0.49 +/- 0.15 mm: scar extension, scar elasticity, bFGF vs. non-bFGF, p<0.01). The durometer reading was significantly lower in bFGF-treated scars than in non-bFGF-treated scars (16.2 +/- 3.8 vs. 29.3 +/- 5.1, p<0.01). Transepidermal water loss, water content, and corneal thickness were significantly less in bFGF-treated than in non-bFGF-treated scars (p<0.01).
The Organisation of Cytoplasm (1991)

At the present time our knowledge of the molecular components of cell cytoplasm is growing rapidly. The number of known species of protein molecule increases with each round of biological journals and the properties of these molecules are rapidly being catalogued, including details of their amino-acid sequences and the genes that code for these. It remains true, however, that the number of different components is so great, and their interactions so complex, that we have only the vaguest impression of how cells actually grow, move and multiply.
Combinatorial synthesis of metal–organic frameworks libraries by click-chemistry (2011)

A key to address advanced MOF materials suitable for more sophisticated applications is to add functionalities of greater complexity in a controlled manner. We report a generic and original post-synthetic modification method starting from amino derived MOFs. The first step consists in converting the amino group into azide (N3). Without isolation nor purification, the desired functionalized material is obtained by grafting the corresponding alkyne using “Click Chemistry”. This work reports for the first time the synthesis of a two-dimensional combinatorial library of 24 functionalized MOFs. We also show that the grafting yield can be controlled from 10 to 100%. Finally, we compare the effect of the grafting yield on the porous volume of (1D) and (3D)MOF porous structures.
Constellation Shaping for Fiber-Optic Channels With QAM and High Spectral Efficiency (2014)

In this letter, the fiber-optic communication channel with a quadrature amplitude modulation (QAM) input constellation is treated. Using probabilistic shaping, we show that high-order QAM constellations can achieve and slightly exceed the lower bound on the channel capacity, set by ring constellations. We then propose a mapping function for turbo-coded bit-interleaved coded modulation based on optimization of the mutual information between the channel input and output. Using this mapping, spectral efficiency as high as 6.5 bits/s/Hz/polarization is achieved on a simulated single channel long-haul fiber-optical link excluding the pilot overhead, used for synchronization, and taking into account frequency and phase mismatch impairments, as well as laser phase noise and analog-to-digital conversion quantization impairments. The simulations suggest that major improvements can be expected in the achievable rates of optical networks with high-order QAM.
Effective Sentence Scoring Method using Bidirectional Language Model for Speech Recognition (2019)

In automatic speech recognition, many studies have shown performance improvements using language models (LMs). Recent studies have tried to use bidirectional LMs (biLMs) instead of conventional unidirectional LMs (uniLMs) for rescoring the $N$-best list decoded from the acoustic model. In spite of their theoretical benefits, the biLMs have not given notable improvements compared to the uniLMs in their experiments. This is because their biLMs do not consider the interaction between the two directions. In this paper, we propose a novel sentence scoring method considering the interaction between the past and the future words on the biLM. Our experimental results on the LibriSpeech corpus show that the biLM with the proposed sentence scoring outperforms the uniLM for the $N$-best list rescoring, consistently and significantly in all experimental conditions. The analysis of WERs by word position demonstrates that the biLM is more robust than the uniLM especially when a recognized sentence is short or a misrecognized word is at the beginning of the sentence.