gebhart/patrepeval huggingface dataset:
Pivotal role of PGE2 and IL-10 in the cross-regulation of dendritic cell-derived inflammatory mediators. (2006)

Exposure to pathogens induces antigen-presenting cells (APC) such as macrophages and dendritic cells (DC) to produce various endogenous mediators, including arachidonic acid (AA)-derived eicosanoids, cytokines, and nitric oxide (NO). Many secreted products of activated APC can act by themselves in an autocrine manner and modulate their function. Moreover, the cross-interaction between endogenous bioactive molecules regulates the function of professional APC with important consequences for their ability to activate and sustain immune and inflammatory responses, and to regulate immune homeostasis. Although neglected for many years when compared to their role in cardiovascular homeostasis, cancer and inflammation, the importance of eicosanoids in immunology is becoming more defined. The role of prostaglandin (PG) E2 (PGE2), one of the best known and most well studied eicosanoids, is of particular interest. It modulates the activities of professional DC by acting on their differentiation, maturation and their ability to secrete cytokines. Uniquely among haematopoietic cytokines, interleukin-10 (IL-10) is a pleiotropic molecule that displays both immunostimulatory and immunoregulatory activities. IL-10 has attached much attention because of its anti-inflammatory properties. It modulates expression of cytokines, soluble mediators and cell surface molecules by cells of myeloid origin, particularly macrophages and DC. We previously reported that PGE2 is a potent inducer of IL-10 in bone marrow-derived DC (BM-DC), and PGE2-induced IL-10 is a key regulator of the BM-DC pro-inflammatory phenotype. BM-DC may be considered as an important model to study complex interactions between endogenous mediators, and autocrine IL-10 plays a pivotal role in the crossregulation of AA-derived lipid mediators, cytokines, and NO, with critical effects on immune and inflammatory responses.
Carbon nanotubes from renewable feedstocks: A move toward sustainable nanofabrication (2016)

ABSTRACT A recent development in the manufacturing of carbon nanotubes is the usage of renewable feedstocks as a carbon source. This new development is receiving much support and is a source of excitement among the global research communities due to the positive environmental impacts, reduced carbon footprints, and economic benefits. Various types of renewable feedstocks such as vegetable oils, plant derivatives, and other types of biomasses have been used for the green synthesis of carbon nanotubes by employing conventional fabrication techniques. As the global demand increases for green manufacturing, efforts to synthesize carbon nanotubes from renewable resources are receiving immense attention while also strengthening the concept of biorefinery. This also enables the efficient use of resources as well as improved waste management. The present review summarizes the recent developments and current status of the synthesis of carbon nanotubes using renewable feedstocks along with technical discussions, opportunities for novel precursors, and future directions. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134 , 44255.
Features of Traditional Culture in Chinese Historical Archives and Their Reasons (2006)

Chinese historical archives, which played an important role in cultural history, are an indispensable part of traditional culture. Affected by some factors in the traditional culture, such as paying more attention to continuation, humanities and highly centralized power, Chinese historical archives have four distimct features: powerful continuation, humanities in content, monopoly by the subject and few in number.
Characterization and processing of polyimide thin films for microelectronics application (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCharacterization and processing of polyimide thin films for microelectronics applicationJuey H. Lai, Richard B. Douglas, and Kevin DonohoeCite this: Ind. Eng. Chem. Prod. Res. Dev. 1986, 25, 1, 38–40Publication Date (Print):March 1, 1986Publication History Published online1 May 2002Published inissue 1 March 1986https://pubs.acs.org/doi/10.1021/i300021a010https://doi.org/10.1021/i300021a010research-articleACS PublicationsRequest reuse permissionsArticle Views354Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
The vibroacoustic disease--an emerging pathology. (1999)

Vibroacoustic disease (VAD) is the clinical manifestation of a systemic disease that develops after long-term exposure to noise (> or = 10 yr) which is characterized by large pressure amplitude (> or = 90 dB SPL) within the lower frequency bands (< or = 500 Hz). Noisy environments produce more widespread systemic effects than initially suspected. This paper describes the chronology, population studied, and the statistical treatment used in our studies of VAD over the past 20 yr. We also describe the motivation that led to the evaluation and assessment of the exposed employees. Future research aims are also discussed.
Spear Fishing in Wisconsin: Multicultural education as symbolic violence (2001)

In this article the authors describe how multicultural teacher education can preserve familiar institutional and ideological mechanisms that validate social inequalities. The authors drawn on their own teaching experiences in state and liberal arts colleges, analyzing student discourse collected during activities concerning recent conflict between Native Americans and groups opposed to the exercise of their treaty rights to fish on non-reservation lakes. The analyses employ Bourdieu's analytic framework of sociology of culture to draw distinctions between the positions taken in the state university context, in which the pre-service teachers are mostly working class and white, and the liberal arts context, where the majority of students are from more privileged backgrounds. The findings suggest that multicultural education in its current institutional form puts white workingclass students in an indefensible position in so far as they may identify with those who protest the exercise of Indian rights. The same kind of multicultural education presents less conflict for students in the liberal arts setting. It is conclude that using terms like ' racism ', intended or unintended, to describe the students' underlying dispositions can be an act of symbolic violence, and the authors offer some alternative approaches to multicultural education.
Differences in Fe(II)-N epsilon(His-F8) stretching frequencies between deoxyhemoglobins in the two alternative quaternary structures. (1980)

Resonance Raman spectra have been obtained of the alpha deoxy and beta deoxy subunits within valency hybrid hemoglobins both in the high-affinity (R) and low-affinity (T) structures. Upon conversion from the R to the T structure, the vibrational frequency of the Fe(II)-N epsilon(His-F8) bond changes from 223 to 207 or 203 cm-1 in the alpha deoxy subunit and from 224 to 220 or 217 cm-1 in the beta deoxy subunit. We estimate that the Fe(II)-N epsilon(His-F8) bond is stretched by the R leads to T transition 3 times more in the alpha subunit (0.024 A) than in the beta subunit (0.0085 A) and, accordingly, the strain energy developed in that bond is 8 times larger in the alpha than in the beta subunit. Hence, the oxygen affinity of the alpha and beta subunits may be regulated by different mechanisms.
High-power forward Raman amplifiers employing low-pressure gases in light guides II Experiments (1986)

An experimental study of a high-power forward Raman amplifier pumped by a multibeam KrF laser is presented. The active medium is either CH4 at 3-bar pressure or H2 at 1-bar pressure. As many as 56 pump beams confined in a light guide were combined into a single low-divergence Stokes beam. In CH4 a gain of up to 300 and a power-conversion efficiency of 70% was obtained. The maximum Stokes output energy was 8.4 J. The dependence of gain on pump bandwidth was investigated in H2. A gain of 500 and a conversion efficiency of 65% were obtained. The maximum output energy was 5.0 J.
RSS-Based Location Estimation with Unknown Pathloss Model (2006)

Recently, received signal strength (RSS)-based location estimation technique has been proposed as a low-cost, low-complexity solution for many novel location-aware applications. In the existing studies, radio propagation pathloss model is assumed known a priori, which is an oversimplification in many application scenarios. In this paper we present a detailed study on the RSS-based joint estimation of unknown location coordinates and distance-power gradient, a parameter of pathloss model. A nonlinear least-square estimator is presented and the performance of the algorithm is studied based on CRB and various simulation results. From simulation results it is shown that the proposed joint estimator is especially useful for location estimation in unknown or changing environments
Regioselective Synthesis of Highly Substituted Aromatic Sulfides via Carbonyl−Alkyne Exchange Reaction (1999)

Carbonyl−alkyne exchange reaction of 2,2-dimethyldihydropyran-4-thione-derived dienes with acetylenic ketones leads to highly substituted aromatic sulfides. The reaction proceeds with a high degree of regioselectivity and in good yields. Addition of Et2AlCl considerably increases the scope of usable acetylenic ketones. The starting materials, dihydropyran-4-one and α-alkynyl ketone derivatives, are readily available reactive building blocks. Additional diversity can be introduced through straightforward derivatization reactions at the sulfur atom. The use of solid-supported reagents and trapping agents allows the reaction to be carried out in a parallel format which might render such a concept attractive for the synthesis of compound libraries.
A Merging Control Algorithm of Automated Vehicles Based on Inter-Vehicle Communications (2000)

This paper deals with a merging control of vehicles with inter-vehicle communications, which would greatly contribute to increase safety and decrease traffic congestion. Algorithms for merging control of vehicles using a concept of a virtual vehicle and for inter-vehicle communications for the control of platoons are presented. A virtual vehicle is generated by mapping a vehicle on a lane into another lane, in order to enable longitudinal control between vehicles to make smooth merging. The inter-vehicle communications are needed to make a virtual vehicle before merging and to control vehicles during merging. The inter-vehicle communications consist of inter-platoon communications and intra-platoon communications. An algorithm of intra-platoon communications using ring-network is presented. The results of a simulation study and an indoor experiment show the feasibility of the merging control using the inter-vehicle communications.
A 45nm SOI compiled embedded DRAM with random cycle times down to 1.3ns (2010)

A family of embedded DRAMs which are fabricated in 45nm SOI technology is presented. The fast eDRAM has 64 b/BL and achieves a random cycle time of 1.3ns for V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DD</sub> = 1.00V and typical process. The dense eDRAM has 128 b/BL and operates in multi-bank modes up to 1.67GHz for V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DD</sub> = 1.0V and nominal process. The staggered - folded BL architecture with BL twisting over both the array and SAs is described as well as a novel wordline timer which generates a 75% duty cycle signal from a 50% duty cycle clock.
Managing the topology of heterogeneous cluster nodes with hardware locality (hwloc) (2014)

Modern computing platforms are increasingly complex, with multiple cores, shared caches, and NUMA architectures. Parallel applications developers have to take locality into account before they can expect good efficiency on these platforms. Thus there is a strong need for a portable tool gathering and exposing this information. The Hardware Locality project (hwloc) offers a tree representation of the hardware based on the inclusion and localities of the CPU and memory resources. It is already widely used for affinity-based task placement in high performance computing. In this article we present how hwloc is extended to describe more than computing and memory resources. Indeed, I/O device locality is becoming another important aspect of locality since high performance GPUs, network or InfiniBand interfaces possess privileged access to some of the cores and memory banks. hwloc integrates this knowledge into its topology representation and offers an interoperability API to extend existing libraries such as CUDA with locality information. We also describe how hwloc now helps process managers and batch schedulers to deal with the topology of multiple cluster nodes, together with compression for better scalability up to thousands of nodes.
A Signal Processing Method for the Coriolis Mass Flowmeter Based on a Normalized Lattice Notch Filter (2005)

An adaptive normalized notch filter is applied to filter the sensor output signals of a Coriolis mass flowmeter and calculate its frequency. An adaptive line enhancer based on the above-mentioned notch filter extracts the required signals from the noisy data. The sliding Goertzel algorithm is used to calculate the real time phase difference between two signals of this kind. With the frequency and phase difference obtained, the time interval of the two signals and the mass flowrate are derived. The simulation results show that the algorithms studied in this paper are efficient.
Gaussian process regression-based robust free space detection for autonomous vehicle by 3-D point cloud and 2-D appearance information fusion (2017)

Free space detection is crucial to autonomous vehicles while existing works are not entirely satisfactory. As cameras have many advantages on environment perception, a stereo vision-based robust free space detection method is proposed which mainly depends on geometry information and Gaussian process regression. In this work, in order to improve the performance by exploiting multiple source information, we apply Bayesian framework and conditional random field inference to fuse the multimodal information including 2-D image and 3-D point geometric information. Particularly, a Bayesian framework is used for multiple feature fusion to provide a normalized and flexible output. Gaussian process regression is used to automatically and incrementally regress the data, resulting enhanced performance. Finally, conditional random field with color and geometry constrains is applied to make the result more robust. In order to evaluate the proposed method, quantitative experiments on popular KITTI-road data set and qualitative experiments on our own campus data set are tested. The results show satisfactory and inspiring performance compared to the outstanding works and even are competitive to some relevant Lidar-based methods.
The activated protein C (APC)-resistant phenotype of APC cleavage site mutants of recombinant factor V in a reconstituted plasma model (2002)

Recently, new missense mutations in the activated protein C (APC) cleavage sites of human factor V (FV) distinct from the R506Q (FV Leiden) mutation have been reported. These mutations affect the APC cleavage site at arginine (Arg) 306 in the heavy chain of activated FV. Whether these mutations result in APC resistance and are associated with a risk of thrombosis is not clear. The main objective of the present study was to identify the APC-resistant phenotype of FV molecules with different mutations in APC cleavage sites. To study this, recombinant FV mutants were reconstituted in FV-deficient plasma, after which normalized APC-sensitivity ratios (n-APC-SRs) were measured in activated partial thromboplastin time-based and Russell's Viper Venom time-based APC-resistance tests. The mutations introduced in FV were R306G, R306T, R506Q, R679A and combinations of these mutations. Based on the APC-sensitivity ratios, we conclude that the naturally occurring mutations at Arg306 (i.e. FV HongKong and FV Cambridge) result in a mildly reduced sensitivity for APC (n-APC-SR, 0.74-0.87), whereas much lower values (n-APC-SR, 0.41-0.51) are obtained for the mutation at Arg506 (FV Leiden). No effect on the n-APC-SR was observed for the recombinant FV mutant containing the single Ala679 mutation. Because reduced sensitivity for APC, not due to FV Leiden, is a risk factor for venous thrombosis, these data suggest that mutations at Arg306 might be associated with a mild risk of venous thrombosis.
Two-Dimensional Phosphorus Carbide: Competition between sp<sup>2</sup> and sp<sup>3</sup> Bonding (2016)

We propose previously unknown allotropes of phosphorus carbide (PC) in the stable shape of an atomically thin layer. Different stable geometries, which result from the competition between sp(2) bonding found in graphitic C and sp(3) bonding found in black P, may be mapped onto 2D tiling patterns that simplify categorizing of the structures. Depending on the category, we identify 2D-PC structures that can be metallic, semimetallic with an anisotropic Dirac cone, or direct-gap semiconductors with their gap tunable by in-layer strain.
Studies on Tertiary Amine Oxides. XI (1962)

Application of tosyl or benzoyl chloride to quinoline 1-oxide, in the presence of pyridine, chiefly affords 1-(4- or 2-quinolyl)pyridinium salt and its decomposition with aniline gives the corresponding 4- or 2-aminoquinoline. Exchange reaction with aniline hydrochloride, on the other hand, affords anilinoquinoline, which is suitable for following this reaction. Similar reactions progress smoothly in quinoline 1-oxide homologs and isoquinoline 2-oxide. Some considerations were made on the mechanims of this reaction.
Versatile Access to C-4-Substituted 2-Amino-1,3-azoles from Hydropyridines in Oxidative Conditions (2005)

[Chemical reaction: see text] Various substituted 2-aminotetrahydroazolopyridines and 2-aminohexahydroazolopyridines have been prepared by bromine-mediated addition of protected guanidine or urea to hydropyridine derivatives. The pH-dependent regioselective cleavage of the resulting aminal function led to the 2-aminoazole products III. The yields of the bicycles of type II, and their conversion into azoles III depends on the electronic properties of the substituents on the nitrogen of the tetrahydopyridine.
Characterization of glucuronides with a thermospray liquid chromatography/mass spectrometry interface (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCharacterization of glucuronides with a thermospray liquid chromatography/mass spectrometry interfaceDaniel J. Liberato, Catherine C. Fenselau, Marvin L. Vestal, and Alfred L. YergeyCite this: Anal. Chem. 1983, 55, 11, 1741–1744Publication Date (Print):September 1, 1983Publication History Published online1 May 2002Published inissue 1 September 1983https://pubs.acs.org/doi/10.1021/ac00261a023https://doi.org/10.1021/ac00261a023research-articleACS PublicationsRequest reuse permissionsArticle Views139Altmetric-Citations76LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Anaerobic co-digestion of sewage sludge and food waste using temperature-phased anaerobic digestion process (2004)

This study was performed to overcome the low efficiency of anaerobic digestion of sewage sludge and food waste by combining temperature-phased digestion, sequencing batch operation, and co-digestion technology. It was demonstrated that the temperature-phased anaerobic sequencing batch reactor (TPASBR) system for the co-digestion of sewage sludge and food waste resulted in enhanced volatile solids (VS) reduction and methane production rate. At the organic loading rate (OLR) of 2.7 g VS/l/d, the TPASBR system showed the higher VS reduction (61.3%), CH4 yield (0.28 l/g VS(added)) and CH4 production rate (0.41 l CH4/l/d) than those (0.29 l CH4/l/d) of the mesophilic two-stage ASBR (MTSASBR). In the specific methanogenic activity (SMA) tests on thermophilic biomass of the TPASBR system, the average SMA of acetate (93 ml CH4/gVSS/d) was much higher than those of propionate (46 ml CH4/g VSS/d) and butyrate (76 ml CH4/g VSS/d). Also, higher specific hydrolytic activity (SHA, 217 mg COD/g VSS/d) of the biomass supported fast hydrolysis under thermophilic conditions. The track study revealed that the most active period of the 24 h cycle was between 6 and 12 h. The enhanced performance of the TPASBR system could be attributed to longer solids retention time, fast hydrolysis, higher CH4 conversion rate, and balanced nutrient condition of co-substrate. It was verified that this combination could be a promising and practical alternative for the simultaneous recycling of two types of organic fraction of municipal solid waste (OFMSW) with high stability.
Labor and Fetal Heart Rate Decelerations (2011)

Although intrauterine fetal compromise during labor accounts for a small proportion of cerebral palsy cases, fetal hypoxic-ischemic encephalopathy remains an important and sometimes preventable etiology. This paper reviews the mechanisms regulating fetal heart rate responses, pathogenesis of fetal metabolic acidosis, and thresholds for metabolic acidosis associated with hypoxic-ischemic encephalopathy. The knowledge of normal changes in fetal metabolic acidosis during labor together with changes in association with fetal heart rate decelerations, can aid in the interpretation and management of fetal heart rate tracings.
CONFORMATION OF CYCLO(-<scp>l</scp>-PRO-<scp>d</scp>-LEU-<scp>d</scp>-TYR(ME)-<scp>l</scp>-ILE-) PREDICTED BY EMPIRICAL RULES FOR CYCLIC TETRAPEPTIDES WAS EVIDENCED BY 1H- AND 13C-NMR SPECTROSCOPY (1985)

Abstract The predicted cis-trans-cis-trans backbone conformation of cyclo(-l-Pro-d-Leu-d-Tyr(Me)-l-Ile-) (2) has been evidenced by 1H-NMR experiments. Peptide 2 and cyclo(-l-Pro-l-Leu-d-Tyr(Me)-l-Ile-) are the first diaste-reomeric peptides having cis (Dd) and trans (Ld) Leu-Tyr(Me) peptide bonds.