gebhart/patrepeval huggingface dataset:
Penile Pharmacocavernosography and Cavernosometry in the Evaluation of Impotence (1987)

Within the past few years, veno-occlusion of the corpora cavernosa has become generally recognized as an essential prerequisite for adequate penile erection. Veno-occlusive incompetence is suspected to be a frequent cause of impotence. Our recent experience with cavernosography in two normal volunteers and 36 impotent patients indicates that angiography is reliable in evaluating the competence of the veno-occlusive mechanism only if both pharmacocavernosography (PCG) and pharmacocavernosometry (PCM) are applied. Twenty minutes after intracavernosal (IC) injection of a mixture of 60 mg. papaverine and one mg. phentolamine (regitine), 100 ml. of diluted radiographic contrast medium are infused at the rate of one or two ml./sec. while pressure is recorded, and radiographic films are exposed at the rate of one every eight to 15 seconds. PCM and PCG of the corpora cavernosa indicated the overall degree of competence of the cavernosal veno-occlusive mechanisms, and the sites of veno-occlusive incompetence; non-pharmacologic studies were unreliable in these regards. During non-pharmacologic infusion in normals, pressures rose to 40 to 45 mm. Hg, and free efflux could be visualized from multiple venous systems. After pharmacologic injection in normals, all venous channels closed, and pressures rapidly rose toward or above 200 mm. Hg, at which time the infusion was stopped. Veno-occlusive incompetence was defined angiographically when more than minimal efflux occurred during pharmacocavernosography from any venous system. The incompetence could involve the deep penile system, the deep dorsal system, or the spongiosal system, alone or in combination. Severe veno-occlusive incompetence was considered diagnostic of venogenic impotence, and was defined manometrically when IC pressures failed to exceed 100 mm. Hg during infusion of 100 ml. of fluid at 2 mm./second after IC papaverine and phentolamine injection. We believe these angiographic methods will improve the criteria against which other diagnostic and therapeutic methods can be assessed.
Enhanced Degradation of Pesticides in Aqueous Formulations Due to Addition of Calcium Chloride (1987)

Abstract Addition of technical flake CaCl 2 to spray mixtures resulted in substantial alkalinization of all solutions. The pH values of CaCl 2 solutions returned to neutral levels over time (e.g., usually in 24 hr) or could be returned rapidly to neutrality by the addition of CO 2 . These data indicate that the causative agent for alkalinization is Ca(OH) 2 , a byproduct in the Solvay process used to produce technical flake CaCl 2 . Under the alkaline conditions produced by the addition of technical flake CaCl 2 , enhanced degradation of formetanate (Carzol SP), benomyl (Benlate-50WP) and methomyl/(Lannate) was observed to be related directly to CaCl 2 concentration. Azinphos-methyl (Guthion- 50WP) was found to be the most persistent pesticide under these experimental conditions. Chemical names used: ( 0 , 0 -dimethyl-S-[(4-oxo-1,2,3-benzotriazin- 3(4 H )-yl)methyl]phosphorodithioate (azinphos-methyl); methyl[1-[(bu-tylamino)carbonyl]-1 H -benzimidazol-2-yl]carbamate (benomyl); N,N dimethyl- N ’-[3-[[(methylamino)carbonyl]oxy] phenyljmethanimidamide (formetanate); methyl N -[[(methylamino)carbonyl]oxy] ethanimidothioate(methomyl).
Non-alcoholic Fatty Liver Disease in Chinese Medicine Research (2010)

For the past five years, Chinese medicine treatment of non-alcoholic fatty liver disease (NAFLD) made a systematic review of research, from the etiology and pathogenesis, Chinese medicine research, specifically Hosen side research, dialectical classification studies, experimental research in the field discussed in recent years, research progress and set out the advantages of Chinese medicine treatment of NAFLD.
Precise Tiltmeter Subsidence Monitoring Enhances Reservoir Management (2000)

Abstract Subsidence monitoring is most commonly conducted using either level surveys or GPS surveys of elevation monuments to determine changes in elevation across a field as a result of injection and production activities. Several operators near Bakersfield, CA are using tiltmeter-based subsidence monitoring to obtain highly detailed maps of subsidence with continuous data acquisition. The tiltmeter measured subsidence is then correlated to production and injection on a day-by-day basis so the impact of individual injection and production events can be quantified. The data is presented in a video format that allows visual assessment of the field motion. In some fields, the monitoring array is also equipped with monuments for periodic level survey and GPS measurements of the ground motion. This paper discusses the design and installation of tiltmeter subsidence monitoring arrays and the format of the results. In addition, the subsidence data is correlated to field activities to show how the monitoring can be used to correlate ground movement with reservoir events.
Multiuser detection in single-path fading channels (1994)

The performance analysis of maximum likelihood sequence and decorrelating multiuser detectors is developed for the single-path Rayleigh fading channel. The received signal in this multipoint-to-point channel is additively composed of white Gaussian noise and independently faded waveforms from a finite number of asynchronous users. The optimum sequence detector consists of a bank of single-user matched filters followed by a dynamic programming algorithm, has a demodulation complexity per symbol which is exponential in the number of users, and requires the knowledge of the system as well of the fading parameters. The decorrelating detector has a complexity which is polynomial in the number of users, and does not require knowledge of the signal amplitudes, which are assumed to vary slowly relative to the symbol rate. The single-user error rates are presented for both detectors and compared to conventional detection and isolated transmission, and the notion of asymptotic multiuser efficiency is developed for this channel. In contrast to conventional detection; which suffers from near-far effects due to Rayleigh fading, it is shown that the aforementioned multiuser detectors exhibit performance which rivals that of isolated transmission for sufficiently small thermal noise power. The results of the analysis are illustrated with numerical examples and indicate that the near-far problem may be alleviated by a more sophisticated receiver design.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
EXSUFFLATION WITH NEGATIVE PRESSURE (E.W.N.P.) (1954)

THE ELIMINATION of radiopaque material from the tracheobronchial tree of anesthetized dogs was reported in a previous paper.<sup>1</sup>This was accomplished by two devices which produced high-volume expiratory-flow rates simulating the natural cough.* Studies of bronchial dynamics by serial bronchography revealed a twofold dilatation of the medium-sized bronchi in animals subjected to an inflationary pressure of + 40 mm. Hg. The restoration to normal of the blood gas values found in obstructive dyspnea, reported by Cherniack, Gordon, and Drimmer,<sup>5</sup>may be explained in part by the marked dilatation of the bronchi. The development of a more effective technique, whereby there is slow inflation of the lungs, followed by an "explosive expiration," resulted in a total pressure-drop of approximately 100 mm. Hg, with expiratory-flow rates that surpassed those attainable by the most vigorous cough of normal human subjects.<sup>6</sup>A positive pressure blower served to inflate the lungs to a
Lensless Imaging With Compressive Ultrafast Sensing (2017)

Lensless imaging is an important and challenging problem. One notable solution to lensless imaging is a single-pixel camera that benefits from ideas central to compressive sampling. However, traditional single-pixel cameras require many illumination patterns that result in a long acquisition process. Here, we present a method for lensless imaging based on compressive ultrafast sensing. Each sensor acquisition is encoded with a different illumination pattern and produces a time series where time is a function of the photon's origin in the scene. Currently available hardware with picosecond time resolution enables time tagging photons as they arrive to an omnidirectional sensor. This allows lensless imaging with significantly fewer patterns compared to regular single-pixel imaging. To that end, we develop a framework for designing lensless imaging systems that use ultrafast detectors. We provide an algorithm for ideal sensor placement and an algorithm for optimized active illumination patterns. We show that efficient lensless imaging is possible with ultrafast measurement and compressive sensing. This paves the way for novel imaging architectures and remote sensing in extreme situations where imaging with a lens is not possible.
Alteration of epithelial paracellular permeability during corneal epithelial wound healing. (1990)

We studied the paracellular permeability to mannitol of corneas with epithelium of corneal, limbal, or conjunctival origin. Corneas with epithelial defects reepithelialized by corneal or limbal epithelium were nonvascularized; the corneal permeability was initially increased and returned to normal 3 days later. When epithelial defects extended beyond the limbus, they were healed by conjunctival epithelium. If corneas remained avascular or minimally vascularized, the conjunctiva-derived epithelium underwent a transdifferentiation process into a cornealike morphology in which the corneal permeability was initially increased upon complete reepithelialization, and gradually decreased to a level similar to that of normal cornea, 4 weeks after healing. However, when corneas became vascularized, the conjunctiva-derived epithelium retained its original phenotype, and corneal permeability remained increased throughout the 8-month period of study. The deranged barrier functions noted in the above vascularized cornea were demonstrated further by horseradish peroxidase tracer, which was found in the intercellular spaces of conjunctiva-derived epithelium of vascularized corneas but not in the avascular corneas with epithelia of corneal or limbal origin, or transdifferentiated conjunctival epithelium. To study further the effect of subsequent ocular surface trauma, conjunctival biopsy was performed on transdifferentiated avascular corneas 3 months after initial wounding. The biopsy resulted in extensive vascularization in three of eight previously nonvascularized corneas. Two weeks later, the corneal permeability was increased to a level similar to that of conjunctiva. These results indicate that corneal epithelial paracellular permeability correlates well with the status of the epithelial phenotype.
Stereospecific Syntheses of Some Optically Active 5-Substituted 3-Aralkylideneamino-2-oxazolidinones (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereospecific Syntheses of Some Optically Active 5-Substituted 3-Aralkylideneamino-2-oxazolidinonesNicholas D. HarrisCite this: J. Org. Chem. 1963, 28, 3, 745–748Publication Date (Print):March 1, 1963Publication History Published online1 May 2002Published inissue 1 March 1963https://doi.org/10.1021/jo01038a037RIGHTS & PERMISSIONSArticle Views47Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (497 KB) Get e-Alerts Get e-Alerts
Application Service Provision: Risk Assessment and Mitigation (2008)

Many business managers understand the value of renting applications over the Internet, such as lower total cost of ownership, fewer in-house IT staff, more rapid delivery of applications, scalable solutions, and superior cash flow. But there are also risks, such as power shifting asymmetrically to the supplier, suppliers overselling their capabilities, suppliers encountering subcontracting problems, and customer concerns about Internet security and reliability. In conducting ten case studies and surveying 270 companies, we developed a risk-assessment and risk-mitigation framework and learned four lessons about the Application Service Provision (ASP) space. One, ASP sourcing has many of the same risks as traditional IT outsourcing, but the pattern of likely risks differs. Most risks are greater with ASP, but some are the same or less. Two, business managers can learn how to assess ASP risks based on lessons from both traditional IT outsourcing and early ASP adopters. Three, mimicking ASP risk-mitigation strategies will not guarantee success, but many risk mitigation tools are available for most business environments. And four, ASP outsourcing, like all IT out-sourcing, requires significant in-house oversight.
DEC 추천 실제의 상호간 팀 협력 모델에 기초한 치료사의 협력태도 (2019)

이 연구는 치료사와 어린이집 교사 간의 협력 실천방법 모색에 기여하고자, 협력의뢰서를 작성하는 치료사의 협력태도 특징을 ‘DEC 추천실제의 상호간 팀 협력 중심 모델’에서 제시한 기준으로 탐색한 것이다. DEC의 에서 체크리스트로 권장된 ‘상호간 팀 협력 실행방법’의 내용을 치료사와 어린이집 교사와의 협력...
The Three-Dimensional Structure of the Fab′ Fragment of a Human Myeloma Immunoglobulin at 2.0-Å Resolution (1974)

The structural analysis of the Fab' fragment of human myeloma immunoglobulin IgGl(lambda) New has been extended to a nominal resolution of 2.0 A. Each of the structural subunits corresponding to the variable and to the constant homology regions of the light and heavy chains contains two irregular beta-sheets which are roughly parallel to each other and surround a tightly packed interior of hydrophobic side chains. About 50-60% of the amino-acid residues are included in beta-pleated sheets. Sequence alignments between the homology regions of Fab' New obtained by comparison of their three-dimensional structures are given. Some of the sequence variations observed in light and heavy chains and the role of the regions of hypervariable sequence in defining the size and shape of the active site of different immunoglobulin molecules are discussed on the basis of the three-dimensional model of Fab' New.
ChemInform Abstract: A Novel and Efficient Synthesis of Isoguanosine. (1987)

Abstract The aminoimidazolecarboxamides (I) react with benzoyl isothiocyanate (II) to yield the thioureas (III) which are dehydrated and desulfurized to form the nitriles (IV).
Quantized conductance of point contacts in a two-dimensional electron gas (1988)

Ballistic point contacts, defined in the two-dimensional electron gas of a GaAs-AlGaAs heterostructure, have been studied in zero magnetic field. The conductance changes in quantized steps of ${e}^{2}$/\ensuremath{\pi}\ensuremath{\Elzxh} when the width, controlled by a gate on top of heterojunction, is varied. Up to sixteen steps are observed when the point contact is widened from 0 to 360 nm. An explanation is proposed, which assumes quantized transverse momentum in the point-contact region.
Ca<sup>2+</sup>—ATPase and Na<sup>+</sup>‐K<sup>+</sup>–ATPase content in skeletal muscle from malignant hyperthermia patients (1992)

The purpose of this study was to determine the concentration of Ca(2+)-ATPase and Na(+)-K(+)-ATPase in biopsies from vastus lateralis muscle of 24 patients, who underwent a diagnostic contracture test for susceptibility to malignant hyperthermia (MH). Ca(2+)-ATPase was quantified as the Ca(2+)-dependent 32P incorporation in whole muscle homogenates. Na(+)-K(+)-ATPase was quantified as the [3H]ouabain-binding capacity in intact muscle samples. These methods avoid isolation of membranes, a procedure that may influence the results due to interindividual variation in recovery. The results show that both enzymes can be determined in (frozen) muscle biopsies weighing 50 mg. Neither the concentration of Ca(2+)-ATPase nor that of Na(+)-K(+)-ATPase differed in biopsies from subjects diagnosed as susceptible (MHS) or nonsusceptible (MHN) to MH. Our data support the view that changes in the concentration of Ca(2+)-ATPase and/or Na(+)-K(+)-ATPase do not play a primary role in the pathogenesis of MH.
Antinociceptive effects of counterirritants. (1994)

Counterirritants such as l-menthol, methyl salicylate, camphor, thymol and capsaicin are widely used in the treatment of mild pains and itches by topical application. However, little experimental research on counterirritants has been reported. In the present study, we investigated the antinociceptive effects and mechanisms of topically applied counterirritants, especially those of l-menthol. From the formalin test in mice, l-menthol (at a concentration of 1-30% in ethanol) showed a major effect in the early phase of pain response (0-5 min). In contrast, the antinociceptive effects of indomethacin (10 mg/kg, p.o.) were found only in the late phase of pain response (15-25 min). Furthermore, morphine (0.75-6 mg/kg, s.c.) dose-dependently inhibited both phases. l-Menthol-induced analgesia during the early phase was significantly blocked by naloxone and potentiated by bestatin. The antinociceptive effects of l-menthol were furthermore examined in dexamethasone-treated mice. l-Menthol also produced antinociceptive effects in the hot plate test of mice and hind paw pressure test of rats. l-Menthol showed mild surface and infiltrating anesthetic effects in guinea pigs. l-Menthol did not inhibit both carrageenin-induced paw edema of rats and the synthesis of prostaglandin E2 in vitro. Based on these findings, we proposed that l-menthol produces antinociceptive effects by activation of the endogenous opioid system and/or partially by local anesthetic actions without anti-inflammatory effects.
Coordination, organometallic and related chemistry of tris(pyrazolyl)methane ligands (2005)

Tris(pyrazolyl)methanes are the neutral analogues of the widely exploited and highly useful tris(pyrazolyl)hydroborates, yet by comparison with their boron based counterparts their chemistry is underdeveloped. Recent breakthroughs in the synthesis of ring-substituted tris(pyrazolyl)methanes offer the opportunity for the development of this useful and promising class of ligand. This review summarises the current state of the coordination and organometallic chemistry of tris(pyrazolyl)methanes and highlights areas in which development is likely to occur.
Effect of Lodoxamide on in vitro and in vivo Conjunctival Immediate Hypersensitivity Responses in Rats (1993)

The antiallergic compound, lodoxamide, was evaluated for its abilities to attenuate a local allergic reaction in rat conjunctiva in vivo and to inhibit rat conjunctival mast cell mediator release in vitro. Topically applied lodoxamide (0.01, 0.10 and 1.0%, w/v) dose-dependently reduced the allergic response (23, 43 and 72%, respectively) in vivo. Lodoxamide was more effective than cromolyn sodium, N-acetyl aspartyl glutamic acid (Naaxia) and levocabastine, and 25 (7-200) times more potent than nedocromil sodium in direct comparisons. Addition of lodoxamide (10 micrograms/ml) to sensitized conjunctival tissue in vitro immediately prior to antigen challenge significantly reduced the amount of histamine released by the tissue. These data suggest that lodoxamide's in vivo anti-allergic activity in the conjunctiva is associated with its ability to prevent allergic mediator release from mast cells contained in this same tissue.
Drug Release Properties of the Microcapsules of Adriamycin Hydrochloride with Ethylcellulose Prepared by a Phase Separation Technique (1984)

Adriamycin hydrochloride was microencapsulated with ethylcellulose by a phase separation method to develop a prolonged release dosage form. Polyisobutylene (PIB) was used as a coacervation-inducing agent to control the particle size and drug release rate of the resultant microcapsules. With increasing the concentration of PIB (1 to 3 %) the average diameter of the microcapsules decreased, due to the fact that the microcapsules were discreted to a single microcapsule. At low concentration of PIB, the resultant microcapsules were agglomerated, which resulted in increasing the size. The microcapsules prepared with PIB 2 % prolonged desirably the drug release from the microcapsules. A little size effects of the microcapsules on the drug release rate was found for the microcapsules with PIB 2 % and 3 %.
Cross-talk and ringing on a multilayer PCB (2003)

A description is given of a new release of Greenfield, a family of analog simulation software tools that simulate the behavior of multilayer printed-circuit boards (PCBs) under high-speed switching conditions. Per unit length inductance, capacitance and resistance matrices-for systems of coupled multiconductor microstrips and striplines-are produced by the two-dimensional Green's function boundary-element field solver Greenfield2d. Greenfield2d supports generation of different SPICE subcircuit models of coupled transmission lines. These models can be subsequently used in Phyllis or any tool which supports SPICE netlist syntax. Cross-sections of multiconductor structures including stripline, microstrip and no-ground connections are shown. The boundary-element procedure is used to generate circuit models for these electromagnetically coupled structures. Time-domain signals and cross-talk waveforms are shown in the time domain.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>