gebhart/patrepeval huggingface dataset:
Increasing the Power Density for Axial-Piston Swash-Plate Type Hydrostatic Machines (2013)

Power density is an assumed attribute of an axial-piston swash-plate type hydrostatic machine. As such, very little research has been conducted to examine the nature and limit of this machine's power density and the literature is all but void of this important topic. This paper is being written to fill this void, and to provide a thorough analysis of the machine's power density. This paper is also aimed at identifying the most significant parameters that may be adjusted to increase the power density for a typical machine. As shown in this research, the power density of an axial-piston machine depends upon four dimensionless quantities that are characteristic of the machine's rotating group. As it turns out, the allowable stress for the cylinder block is the most sensitive parameter that may be adjusted for increasing the power density of this machine. It is further shown that increasing the machine's swash-plate angle, and reducing the minimum overhang length for the pistons, will have a significant impact on the power density as well. It is significant to note that altering the number of pistons in the design has essentially no impact on the power density of the machine and therefore the selection of this design parameter must be based upon other design objectives. In conclusion, it is shown in this paper that the power density of a typical machine may be increased by as much as 64% by altering a few of these parameters within a realistic realm of constraint.
A VLSI array for computing the DFT based on RNS (2005)

The Discrete Fourier Transform (DFT) has been adopted in a wide spectrum of Digital Signal Processing (DSP) applications due to the advances in VLSI technology, One dimensional systolic arrays are employed to implement the DFT algorithms where N DFT points can be computed in O(N) time using O(N) area. Residue Number System (RNS) is used to achieve parallelism on the mathematical level, as the arithmetic operations are performed independently for each modulus. Modularity has been realized on both functional and layout levels. Two types of arrays are described. The first array offers higher speed performance, while the second requires less area and is more general. The proposed structures are based on bit parallel processing and lend themselves to pipelining.
Salt-sensitive aortic aneurysm and rupture in hypertensive transgenic mice that overproduce angiotensin II. (1998)

We studied the effect of excessive salt intake on vascular lesion development in hypertensive transgenic mice that overproduce angiotensin II, ie, Tsukuba hypertensive mice (THM). At 6 weeks of age, THM and C57BL/6J (controls) were given either 1% sodium chloride ("salt-loaded") drinking water or tap water for 30 days. Salt-loaded THM, but not controls, suffered frequent thoracic or abdominal cavity hemorrhage. THM mortality after 7 days of salt loading was 23%; after 30 days of salt loading, it rose to 67%. Hemorrhaging occurred due to the development of aortic aneurysm and rupture at the aortic arch and aorta near the renal arteries. Vascular lesions progressed with structural degeneration of the aortic media. Electronmicroscopic analysis revealed that intact THM already exhibited vascular remodeling consisting of vascular smooth muscle cells (VSMCs) with developed organelles and an increased extracellular matrix. Salt-loaded THM suffered aggravated vascular hypertrophy and vascular structure destruction by plasma material invasion, necrosis of VSMCs possessing extremely swollen cytoplasm and abundant organelles, and interlamellar bleeding, resulting in aortic aneurysm and eventual rupture. Interestingly, blood pressure levels and heart rates in salt-loaded THM did not differ significantly from those of controls; plasma renin activity between drinking regimens was also comparable between the two groups. Drinking volume and the concentration of atrial natriuretic peptide (ANP) in plasma, however, were significantly higher in salt-loaded THM than in intact THM. In addition to aneurysm localization, the findings regarding drinking volume and plasma ANP suggest that aortic aneurysm and rupture in salt-loaded THM occurred as the result of an unknown mechanical stress, other than blood pressure, on the aortic wall. High salt ingestion is involved in the development of thoracic and abdominal aortic aneurysm in the presence of hypertension in the activated renin-angiotensin system. THM should therefore serve as a useful animal model for studying the pathogenesis of aortic aneurysm accompanied by hypertension.
Programmed thermal field-flow fractionation (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTProgrammed thermal field-flow fractionationJ. Calvin. Giddings, LaRell K. Smith, and Marcus N. MyersCite this: Anal. Chem. 1976, 48, 11, 1587–1592Publication Date (Print):September 1, 1976Publication History Published online1 May 2002Published inissue 1 September 1976https://pubs.acs.org/doi/10.1021/ac50005a043https://doi.org/10.1021/ac50005a043research-articleACS PublicationsRequest reuse permissionsArticle Views86Altmetric-Citations54LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Requirements for hierarchical storage management at AT&T Bell Laboratories (2002)

The author describes the computing environment and requirements for a hierarchical storage management (HSM) product within the AT&T Bell Laboratories. He first describes the data storage services provided within AT&T Bell Laboratories. Next, he describes the application environment of some of the major UTS and workstation customers. The applications considered include UTS-based software development and field support, workstation-based general computing, and workstation-based system test labs. Finally, he presents a concise statement of the HSM requirements, a method to measure these requirements, and the rationale behind each requirement.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Spectroscopic techniques in the study of protein binding: the use of 1-anilino-8-naphthalenesulphonate as a fluorescent probe for the study of the binding of iophenoxic and iopanoic acids to human serum albumin. (1973)

The binding of iopanoic and iophenoxic acids to human serum albumin (HSA) has been studied by spectroscopic techniques. The protein fluorescence of human serum albumin was quenched by the binding of either drug. Analysis of this quenching indicated that iophenoxic acid binds very tightly to at least one site on the albumin molecule so that, at less than a 1:1 ratio of iophenoxic acid to HSA, almost no drug exists free in solution. This provides an explanation for the unusual pharmacokinetics of this drug. The binding of 1-anilino-8-naphthalenesulphonate (ANS) to human serum albumin has been studied and is shown to be consistent with strong binding at one site and weaker binding at three further sites. The fluorescence of ANS bound to HSA was increased by iophenoxic acid and decreased by iopanoic acid. Measurements of fluorescence emission spectra and fluorescence lifetimes indicated that the drug-induced changes in fluorescence were due to changes in the quantum yield of the bound ANS. It is concluded that iophenoxic and iopanoic acids induce different changes in albumin conformation which can be detected by changes in the fluorescence of bound ANS. Iophenoxic acid enhanced the fluorescence of ANS bound to its tight site but displaced ANS from the weaker binding sites. Furthermore, 1 mole of iophenoxic acid displaced more than 1 mole of ANS, indicating that this effect was also related to the drugnduced change in the albumin structure.
Human Periosteum Is a Source of Cells for Orthopaedic Tissue Engineering: A Pilot Study (2011)

Cultured periosteal cells may contribute to tissue formation and may be applicable for tissue engineering applications.
The Role of Disulfide Bonds in Structure and Activity of Chlorotoxin (2014)

The disulfide bonds of chlorotoxin are important for its structure and stability and have a minor role in its activity against cell migration.
A Review of Distributed Fibre Optic Sensors for Geo-Hydrological Applications (2017)

Distributed optical fibre sensing, employing either Rayleigh, Raman, or Brillouin scattering, is the only physical-contact sensor technology capable of accurately estimating physical fields with spatial continuity along the fibre. This unique feature and the other features of standard optical fibre sensors (e.g., minimal invasiveness and lightweight, remote powering/interrogating capabilities) have for many years promoted the technology to be a promising candidate for geo-hydrological monitoring. Relentless research efforts are being undertaken to bring the technology to complete maturity through laboratory, physical models, and in-situ tests. The application of distributed optical fibre sensors to geo-hydrological monitoring is here reviewed and discussed, along with basic principles and main acquisition techniques. Among the many existing geo-hydrological processes, the emphasis is placed on those related to soil levees, slopes/landslide, and ground subsidence that constitute a significant percentage of current geohazards.
[Collagen synthetic activity following filtration surgery in rabbits]. (1995)

We evaluated collagen synthetic activity, which plays an important role in wound healing, following experimental filtration surgery in rabbits. Collagen synthetic activity was measured by immunohistochemistry for prolyl 4-hydroxylase beta-subunit and type I procollagen. Trabeculectomy was performed on albino rabbit eyes, with the filtering site harvested on postoperative days 1, 4, 7, 14, and 28. Samples were fixed with 10% buffered formalin for 12 hours and prepared for paraffin section, and each antigen was detected in filtering site tissue using avidin-biotinylated peroxidase complex. Immunoreaction of prolyl 4-hydroxylase beta-subunit or type I procollagen increased from day 4 to 14 and markedly decreased at day 28. These findings show that prolyl 4-hydroxylase and type I procollagen are markedly produced almost simultaneously, and collagen synthetic activity following filtration surgery continues for over 14 days in the process of wound healing.
Formation and Solid State Structures of Highly Crystalline Guanidinium Salts of Sulfonated Tertiary Phosphanes (2002)

Formation of highly crystalline guanidinium salts of sulfonated triphenylphosphane derivatives is demonstrated as a general method for obtaining samples suitable for single crystal X-ray structural characterization. The structures of sulfonated phosphane ligands 1 – 5 have been determined. Extensive hydrogen bond networks between guanidinium N-H donors and -SO3 oxygens as acceptors and/or π-π interactions stabilize the structures.
Phase-Only Transmit Beam Broadening for Improved Radar Search Performance (2007)

The operational value of applying transmit beam broadening in radar search is considered. Test cases are established to evaluate search radar performance with beam broadening and without beam broadening, and also for different beam broadening arrangements. The test cases are evaluated according to search occupancy and probability of detection performance. The advantage of beam broadening for a horizon search fence is demonstrated; this approach extends to generic search fence design, and is particularly advantageous for broadening factors of 3:1 or higher.
Measurements of hot-electron conduction and real-space transfer in GaAs-Al<i>x</i>Ga1−<i>x</i>As heterojunction layers (1981)

Measurements of the current-voltage characteristics of GaAs-AlxGa1−xAs heterojunction layers are reported. The experimental results are consistent with the idea of real-space transfer of the electrons out of the GaAs into the AlxGa1−xAs under hot-electron conditions. Current saturation and negative differential resistance are observed as predicted by Monte Carlo simulations.
Comparison of the Spherical Deflector and the Cylindrical Mirror Analyzers (1968)

The calculated performance of electrostatic analyzers of the cylindrical and spherical deflection type are compared. It is shown that considering geometrical terms through the third order the cylindrical device is significantly superior.
Effects of oleate-rich and linoleate-rich diets on the susceptibility of low density lipoprotein to oxidative modification in mildly hypercholesterolemic subjects. (1993)

We report the results of feeding oleate- or linoleate-enriched diets for 8 wk to mildly hypercholesterolemic subjects and the resulting alterations in composition and functional properties of their plasma LDL and HDL. LDL isolated from subjects on oleate-enriched diets was less susceptible to copper-mediated oxidation, as measured by conjugated diene and lipid peroxide formation, and less susceptible to LDL-protein modification, as evidenced by reduced LDL macrophage degradation after copper- or endothelial cell-induced oxidation. For all subjects, the percentage of 18:2 in LDL correlated strongly with the extent of conjugated diene formation (r = 0.89, P < 0.01) and macrophage degradation (r = 0.71, P < 0.01). Oxidation of LDL led to initial rapid depletion of unsaturated fatty acids in phospholipids followed by extensive loss of unsaturated fatty acids in cholesteryl esters and triglycerides. Changes in HDL fatty acid composition also occurred. However, HDL from both dietary groups retained its ability to inhibit oxidative modification of LDL. This study demonstrates that alterations in dietary fatty acid composition can effectively alter the fatty acid distribution of LDL and HDL in hypercholesterolemic subjects and that susceptibility to LDL oxidation is altered by these changes. Substitution of monounsaturated (rather than polyunsaturated) fatty acids for saturated fatty acids in the diet might be preferable for the prevention of atherosclerosis.
Offline optimized pulse pattern with a view to reducing DC-link capacitor application to a starter generator (2004)

In an embedded application, electrical equipments are connected to the onboard network. In order to avoid any dysfunction, the DC-link voltage has to be as constant as possible. To achieve this purpose, a high capacitance is inserted in parallel to the network. This paper shows relationship between DC-link voltage ripple and DC-link current ripple by using a simplified equivalent scheme of the onboard network. Control of the DC-link current permits a reduction in the capacitor's size without increasing significantly the DC-link voltage ripple. An optimal pulse width modulation (PWM) strategy is proposed to control DC-link current harmonics. The general equation system and the numerical computation of simple examples are developed in this paper. A starter generator application embedded in an automotive vehicle is used to illustrate our work.
On the role of FAN1 in Fanconi anemia (2012)

Fanconi anemia (FA) is a rare bone marrow failure disorder with defective DNA interstrand crosslink repair. Still, there are FA patients without mutations in any of the 15 genes individually underlying the disease. A candidate protein for those patients, FA nuclease 1 (FAN1), whose gene is located at chromosome 15q13.3, is recruited to stalled replication forks by binding to monoubiquitinated FANCD2 and is required for interstrand crosslink repair, suggesting that mutation of FAN1 may cause FA. Here we studied clinical, cellular, and genetic features in 4 patients carrying a homozygous 15q13.3 micro-deletion, including FAN1 and 6 additional genes. Biallelic deletion of the entire FAN1 gene was confirmed by failure of 3'- and 5'-PCR amplification. Western blot analysis failed to show FAN1 protein in the patients' cell lines. Chromosome fragility was normal in all 4 FAN1-deficient patients, although their cells showed mild sensitivity to mitomycin C in terms of cell survival and G(2) phase arrest, dissimilar in degree to FA cells. Clinically, there were no symptoms pointing the way to FA. Our results suggest that FAN1 has a minor role in interstrand crosslink repair compared with true FA genes and exclude FAN1 as a novel FA gene.
Metabolic Versatility and Antibacterial Metabolite Biosynthesis Are Distinguishing Genomic Features of the Fire Blight Antagonist Pantoea vagans C9-1 (2011)

Identifying key determinants contributing to disease suppression allows the development of procedures to follow their expression in planta and the genome sequence contributes to rationale risk assessment regarding the use of the biocontrol strain in agricultural systems.
DC biased electro-optic polymer waveguide modulators with low half-wave voltage and high thermal stability (1999)

The full potential of second-order nonlinear polymers can be utilized in electro-optic polymer modulators with a DC biased operation scheme to greatly reduce the half-wave voltage. This technique makes use of the total achievable electro-optic coefficient, which can be more than three times the value that is used by the conventional devices of poled electro-optic polymer. As the result of the DC bias and with high-μβ chromophores, a low half-wave voltage of 1.5 V was achieved with 2-cm-long birefringent waveguide modulators at the wavelength of 1.3 μm. Results of a 200°C stability experiment indicate that this scheme also enables electro-optic polymer devices to meet the short-term high-temperature stability requirement because the polymer does not need to be poled prior to high-temperature steps. © 1999 Society of Photo-Optical Instrumentation Engineers.
Phenotypic and Genomic Analyses of a Fast Neutron Mutant Population Resource in Soybean   (2011)

Mutagenized populations have become indispensable resources for introducing variation and studying gene function in plant genomics research. In this study, fast neutron (FN) radiation was used to induce deletion mutations in the soybean (Glycine max) genome. Approximately 120,000 soybean seeds were exposed to FN radiation doses of up to 32 Gray units to develop over 23,000 independent M2 lines. Here, we demonstrate the utility of this population for phenotypic screening and associated genomic characterization of striking and agronomically important traits. Plant variation was cataloged for seed composition, maturity, morphology, pigmentation, and nodulation traits. Mutants that showed significant increases or decreases in seed protein and oil content across multiple generations and environments were identified. The application of comparative genomic hybridization (CGH) to lesion-induced mutants for deletion mapping was validated on a midoleate x-ray mutant, M23, with a known FAD2-1A (for fatty acid desaturase) gene deletion. Using CGH, a subset of mutants was characterized, revealing deletion regions and candidate genes associated with phenotypes of interest. Exome resequencing and sequencing of PCR products confirmed FN-induced deletions detected by CGH. Beyond characterization of soybean FN mutants, this study demonstrates the utility of CGH, exome sequence capture, and next-generation sequencing approaches for analyses of mutant plant genomes. We present this FN mutant soybean population as a valuable public resource for future genetic screens and functional genomics research.
High-dynamic-range high-optical-isolation wavelength-sensitive thin film filter-based variable fiber optic attenuator (2006)

A wavelength-sensitive variable fiber optic attenuator (VFOA) is introduced by incorporating the movable optical mirror with a fixed desired thin film filter (TF) in a compact in-line reflective architecture. Our TF-based wavelength-sensitive VFOA features low component count, high attenuation dynamic range, and high optical isolation. Experimental proof of concept using an off-the-shelf measured 1545.71-nm TF and a mechanically movable mirror shows a 4.64-dB optical loss, and a low polarization-dependent loss of 0.12 dB at the output port. A high optical attenuation dynamic range of >43 dB with a better than 30-dB optical isolation is obtained. Several proposed reflective wavelength-sensitive TF-based VFOAs can also be cascaded to form a low-cost, compact, multiwavelength amplitude controller.
Study of a Miniature Probe Fluorescence Temperature Sensor (2012)

In this paper, study of theory and technique experiment has done about noncontact fluorescence temperature detection technique. This system is particularly adapt to the temperature measurement in the rang of 0°C to130°C. The calibration graph was shown to be highly reproducible when the probe is temperature cycled. A change in drive current from 5 to 30mA yields a spectral shift of the peak emission of only a few nanometers. The drive current to the LED can easily be kept within the required narrowly defined bounds through the control circuitry. This system has resolved the temperature measurement problem in special environment and electromagnetic interference environmental.
NOTEWORTHY PROFESSIONAL NEWS (2003)

Advances in Neonatal Care: February 2003 - Volume 3 - Issue 1 - p 2 doi: 10.1053/adnc.2003.50009
EV Battery Life Extension in Field Testing (1997)

<div class="htmlview paragraph">Results of the Charger Test Project conducted by Arizona Public Service (APS) indicated the importance of the charger/charge algorithm/battery interface with respect to battery capacity. It also indicated that EVs rapidly charged demonstrated longer cycle life in field testing without reduction in capacity. Additional testing conducted by APS has shown that cycle life of the batteries is strongly related to the charging scheme utilized. Application of results of laboratory charging to the charge scheme utilized in this testing has been hampered by extremely long test periods in field tests designed to cycle batteries to the end of life. Development of a predictive method of cycle life extrapolation based upon microscopic analysis promises to reduce the time required for battery cycle life testing.</div>
Principles and Applications of Photochemistry (2010)

A modern introduction to photochemistry covering the principles and applications of this topic from both a physical chemistry and organic chemistry angle. Coverage ranges from subjects such as lasers, the atmosphere, biochemistry, medicine and industry and also includes the latest developments in relation to photochemical molecular machines, photodynamic therapy applied to cancer, photochromatic imaging, and photostabilizers. Little in the way of prior knowledge is assumed, and the reader is aided by numerous worked examples, learning objectives, chapter summaries and problems.