gebhart/patrepeval huggingface dataset:
Implementation of a high performance wireless LAN (2002)

A system is presented that implements an indoor microwave LAN that approaches the performance of fibre optic LANs. The goal of the system is to produce a bit rate of 150 Mbit/s with a bit error rate of 10/sup -12/ in a 30 m cell. The high bit rate is achieved by combining hundreds of low speed signals with orthogonal frequency division multiplexing (OFDM) so that no channel equalization is required. The low bit error rate is achieved through a combination of antenna diversity and coding. Results from a prototype network are presented. The paper also discusses the physical layer of the network and begins with a brief description of the difficulties of sending high speed data through a multipath radio channel.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Creation of stable, low work function surfaces on Si by implantation of 3 keV Cs+ (2002)

Silicon surfaces having native oxides were implanted with 3 keV Cs+ ions and annealed. Implanted doses of 1, 1.7, and 3×1016 Cs/cm2 led to room-temperature work functions with stable, reproducible values of 2.3±0.15 eV after vacuum annealing at 100–560 °C. The resulting surfaces have been characterized with regard to the amount of Cs retained, the thermal and environmental stability of the work function, and the composition and chemistry of the implanted layer. The surface layers consisted of a compound of Si–Cs–O, which is compositionally stable to temperatures of ∼400 °C in vacuum. In addition, we found that these surfaces are stable with regard to exposures to background gases and ambient air.
Sequence specificity of aminoglycoside‐induced stop codon readthrough: Potential implications for treatment of Duchenne muscular dystrophy (2000)

As a result of their ability to induce translational readthrough of stop codons, the aminoglycoside antibiotics are currently being tested for efficacy in the treatment of Duchenne muscular dystrophy patients carrying a nonsense mutation in the dystrophin gene. We have undertaken a systematic analysis of aminoglycoside-induced readthrough of each stop codon in human tissue culture cells using a dual luciferase reporter system. Significant differences in the efficiency of aminoglycoside-induced readthrough were observed, with UGA showing greater translational readthrough than UAG or UAA. Additionally, the nucleotide in the position immediately downstream from the stop codon had a significant impact on the efficiency of aminoglycoside-induced readthrough in the order C > U > A ≥ G. Our studies show that the efficiency of stop codon readthrough in the presence of aminoglycosides is inversely proportional to the efficiency of translational termination in the absence of these compounds. Using the same assay, we analyzed a 33–base pair fragment of the mouse dystrophin gene containing the mdx premature stop codon mutation UAA (A), which is also the most efficient translational terminator. The additional flanking sequences from the dystrophin gene do not significantly change the relatively low-level aminoglycoside-induced stop codon readthrough of this stop codon. The implications of these results for drug efficacy in the treatment of individual patients with Duchenne muscular dystrophy or other genetic diseases caused by nonsense mutations are discussed. Ann Neurol 2000;48:164–169
Effect on Canine Oral Health of Adding Chlorhexidine to a Dental Hygiene Chew (1998)

A study to compare the effect of a dental hygiene chew with or without 0.2% chlorhexidine on the development of gingivitis and the accumulation of dental deposits was performed using 11 small dogs. Confirming previous data, the daily addition of a standard chew to a dry diet resulted in significantly less gingivitis and calculus after 3 weeks compared with feeding the dry diet alone. Addition of chlorhexidine to the chew made no difference to the degree of gingivitis or the amount of calculus that accumulated, but did result in significantly less plaque accumulation after 3 weeks. The abrasiveness of the chew, rather than the antibacterial activity of chlorhexidine, is likely to have contributed the most to the maintenance of oral health in dogs with mild gingivitis.
NASA/American Cancer Society high-resolution flow cytometry project-I (2000)

The high-resolution ENV versus DNA analyses are highly reliable, sensitive, and can be used for the detection of near-diploid tumor cells that are difficult to identify with conventional cytometers. ENV/DNA ratio may be a useful parameter for detection of aneuploid populations.
Microwave-assisted route for synthesis of nanosized metal oxides (2007)

Microwave-assisted route for the synthesis of nanomaterials has gained importance in the field of synthetic technology because of its faster, cleaner and cost effectiveness than the other conventional and wet chemical methods for the preparation of metal oxide nanoparticles. In the present work, synthesis of metal oxide nanoparticles viz., γ-Fe2O3, NiO, ZnO, CuO and Co-γ-Fe2O3 were carried out by microwave-assisted route through the thermal decomposition of their respective metal oxalate precursors employing polyvinyl alcohol as a fuel. The metal oxide nanoparticles are then characterized for their size and γ to α (in γ-Fe2O3) transition and structure by employing powder X-ray diffraction (XRD) pattern, high-temperature X-ray diffraction (HTXRD) pattern and Fourier transform infrared (FT-IR) spectral studies. The morphology of the samples ranged from nanorods to irregular-shaped particles for different metal oxide samples on the basis of scanning electron microscopy and transmission electron microscopy images. Frequency-dependent dielectric study of the ferrite samples (γ-Fe2O3 and Co-Fe2O3) showed a similar behaviour, where the dielectric constant decreased rapidly with increase in frequency. Possible explanation for this behaviour is given.
Understanding the Influences that Contribute to African American Males Pursuing STEM Majors at Post-Secondary Institutions: A Review of Literature (2017)

Science, technology, engineering, and mathematics (STEM) is a growing discipline. STEM jobs are projected to grow exponentially within the next decade and future graduates are needed to fill those positions. Although STEM careers are in high demand, African American males are pursuing STEM majors, however, they have been found to pursue STEM majors at a much lower rate than their White and Asian/Pacific Islander peers. This literature review seeks to present research evidence that examines and explores the reasons why African American males pursue science, technology, engineering, and mathematics (STEM) majors at the post-secondary level. This review presents three dominant reasons why this demographic is persisting with the STEM discipline as well as recommendations to practitioners and researchers that may serve African American males by helping them in their pursuits.
Elasto-capillarity: deforming an elastic structure with a liquid droplet (2010)

Although negligible at macroscopic scales, capillary forces become dominant as the sub-millimetric scales of micro-electro-mechanical systems (MEMS) are considered. We review various situations, not limited to micro-technologies, where capillary forces are able to deform elastic structures. In particular, we define the different length scales that are relevant for 'elasto-capillary' problems. We focus on the case of slender structures (lamellae, rods and sheets) and describe the size of a bundle of wet hair, the condition for a flexible rod to pierce a liquid interface or the fate of a liquid droplet deposited on a flexible thin sheet. These results can be generalized to similar situations involving adhesion or fracture energy, which widens the scope of possible applications from biological systems, to stiction issues in micro-fabrication processes, the manufacturing of 3D microstructures or the formation of blisters in thin film coatings.
Simultaneous static and dynamic light scattering (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSimultaneous static and dynamic light scatteringS. Bantle, Manfred Schmidt, and Walther BurchardCite this: Macromolecules 1982, 15, 6, 1604–1609Publication Date (Print):November 1, 1982Publication History Published online1 May 2002Published inissue 1 November 1982https://pubs.acs.org/doi/10.1021/ma00234a028https://doi.org/10.1021/ma00234a028research-articleACS PublicationsRequest reuse permissionsArticle Views1196Altmetric-Citations132LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Satellite ultraquiet isolation technology experiment (SUITE) (2002)

An experimental active vibration isolation called Satellite Ultraquiet Isolation Technology Experiment (SUITE) is described in detail. SUITE is a piezoelectric-based technology demonstration scheduled to fly in 2000 or 2001 on board the PICOSat spacecraft. SUITE is designed to show that the effect of small vibrations on spacecraft instrument effectiveness can be reduced significantly. Control from the ground station is planned for the first year after launch. A description of the PICOSat spacecraft and the other considerations influencing the development of the flight hardware begins the paper. Experiment goals are listed. The mechanical and electromechanical construction of the SUITE hexapod assembly is described, including the piezoelectric actuators, motion sensors, and electromagnetic actuators. The data control system is also described, including the digital signal processor and spacecraft communication. The main features of the software used for real-time control and the supporting Matlab software used for control system development and data processing are summarized. Initial test results are presented.
Assessing combinatorial strategies to multimerize libraries of single‐domain antibodies (2012)

Single-domain antibodies (SDAs) are among the most studied and interesting antibody fragments. These molecules combine advantages of antibodies and small molecules. However, SDAs present a low efficiency of in vivo targeting because of their low binding avidity and fast clearance from blood circulation. Multimerization of SDA can overcome these drawbacks and increase their therapeutic potency. In this work, we developed and compared three strategies that allow construction of SDA dimers derived from rabbit light chains--PCR overlap, sticky PCR, and restriction/ligation. The restriction/ligation strategy proved to be the most efficient and feasible method to construct a successful library of SDA dimers. To further explore this technique, we constructed different libraries that differed in linker length between the two SDAs, and assessed its efficiency to deliver antigen-specific SDA dimers. We efficiently increased both the molecular size and avidity of antibody fragments, increasing the possibility of these molecules to bind to their antigen. Therefore, this work describes efficient tools for therapeutic development of SDA dimers.
Silver-Based Low-Emissivity Coating Technology for Energy- Saving Window Applications (2017)

Low-emissivity (low-E) technology is a unique and cost-effective solution to save energy in buildings for different climates. Its development combines advances in materials science, vacuum deposition, and optical design. In this chapter, we will review the fundamentals of energy saving window coatings, the history of its application, and the materials used. The current low-E coating technologies are overviewed, especially silver-based low-E technologies, which comprise more than 90% of the overall low-E market today. Further, the advanced understanding of generating high-quality silver thin films is discussed, which is at the heart of silver-based low-E product technology development. How the silver thin film electrical, optical, and emissivity properties are influenced by their microstructure, thickness, and by the materials on neighboring layers will be discussed from a theoretical and an experimental perspective.
Successful interconnection of SOA-MZI arrays and flip-flops to realize intelligent, all-optical routing (2008)

We demonstrate an intelligent routing system through the interconnection of 8 optical gates. Contention resolution of bursty packets using integrated MZIs and flip-flops is reported with <1dB power penalty.
Materials, Processes, and Characterization of Extended Air-gaps for the Intra-level Interconnection of Integrated Circuits (2008)

Materials, Processes, and Characterization of Extended Air-gaps for the Intra-level Interconnection of Integrated Circuits \n\nSeongho Park\n\n157 pages\n\nDirected by Dr. Paul A. Kohl and Dr. Sue Ann Bidstrup Allen\n\n The integration of an air-gap as an ultra low dielectric constant material in an intra-metal dielectric region of interconnect structure in integrated circuits was investigated in terms of material properties of a thermally decomposable sacrificial polymer, fabrication processes and electrical performance. Extension of the air-gap into the inter-layer dielectric region reduces the interconnect capacitance. In order to enhance the hardness of a polymer for the better process reliabilities, a conventional norbornene-based sacrificial polymer was electron-beam irradiated. Although the hardness of the polymer increased, the thermal properties degraded. A new high modulus tetracyclododecene-based sacrificial polymer was characterized and compared to the norbornene-based polymer in terms of hardness, process reliability and thermal properties. The tetracyclododecene-based polymer was harder and showed better process reliability than the norbornene-based sacrificial polymer. Using the tetracyclododecene-based sacrificial polymer, a single layer Cu/air-gap and extended Cu/air-gap structures were fabricated. The effective dielectric constant of the air-gap and extended air-gap structures were 2.42 and 2.17, respectively. This meets the requirements for the 32 nm node. Moisture uptake of the extended Cu/air-gap structure increased the effective dielectric constant. The exposure of the structure to hexamethyldisilazane vapor removed the absorbed moisture and changed the structure hydrophobic, improving the integration reliability. The integration processes of the air-gap and the extended air-gap into a dual damascene Cu metallization process has been proposed compared to state-of-the-art integration approaches.
First-line treatment of metastatic melanoma: role of nivolumab (2017)

Historically, the median overall survival of metastatic melanoma patients was less than 1 year and long-term survivors were rare. Recent advances in therapies have dramatically shifted this landscape with increased survival rates and the real possibility that long-term disease control is achievable. Advances in immune modulators, including cytotoxic T-lymphocyte antigen-4 and programmed death-1 based treatments, have been an integral part of this success. In this article, we review previous and recent therapeutic developments for metastatic melanoma patients. We discuss advances in immunotherapy while focusing on the use of nivolumab alone and in combination with other agents, including ipilimumab in advanced melanoma. One major goal in melanoma research is to optimize combination strategies allowing for more patients to experience benefit while minimizing toxicity. A better understanding of the optimal sequencing, combinations, and mechanisms underlying the development of resistance may provide evidence for rational clinical trial designs of novel immunotherapy strategies in melanoma and other cancer subtypes.
Linear Alpha-Olefins by Catalytic Oligomerization of Ethylene (1970)

Abstract This paper describes a new catalytic process for linear alpha-olefins by oligomerization of ethylene using a soluble alkyl aluminum chloride-titanium tetrachloride catalyst. Important catalytic and polymerization variables, such as catalyst activity, selectivity to linear products, and molecular weight, are discussed. An ionic mechanism is proposed to explain the unusual features of this new process.
The Use of In Vitro Metabolism Techniques in the Planning and Interpretation of Drug Safety Studies (1995)

An important issue in toxicology is the suitability of the data obtained with experimental animals for human risk assessment. Because it is not possible to use humans in long-term toxicological studies, the use of animals will continue. However, the data obtained in animal studies can be better extrapolated to the patient by utilizing bridging studies with in vitro models of human drug metabolism. There are 2 basic categories of in vitro methods for the examination of human liver drug metabolism. The first group of in vitro methods consists of the cellular models, which include primary hepatocytes, liver slices, and cell lines. The second group is the use of preparations of the drug-metabolizing enzymes such as tissue homogenates, subcellular fractions, and isolated enzymes. Studies modeling both the human and experimental animal metabolism of a drug are useful in the design of toxicological studies. In vitro studies can identify metabolites, species-specific metabolic routes, and the experimental animal model that best reflects the potential human exposure to the drug and its metabolites. This information can also be useful in the design of the clinical studies by identifying human metabolites, the enzymes responsible for the metabolic clearance of the drug, the effects of genetics and other host factors on the metabolism of the drug, and potential drug-drug interactions. An example of how such information is generated and interpreted is presented.
Unity-gain frequency-independent precision phase-shifter (1984)

The letter describes an operational amplifier circuit which gives a constant (±0.1°) phase shift and a constant (±0.1%) unity gain to a sinusoidal signal, over a frequency band of range ±2%. The circuit incorporates two standard phase-shifters with different characteristics, deployed so that their phase errors mutually cancel as the frequency deviates from its central value. The device has been used as a phase-shifter in a precise negative phase sequence current measurement circuit in a power system.
Cardioprotective Effects of the Calcineurin Inhibitor FK506 and the PAF Receptor Antagonist and Free Radical Scavenger, EGb 761, in Isolated Ischemic/Reperfused Rat Hearts (2000)

Effects of the calcineurin inhibitor FK506, the platelet-activating factor (PAF) antagonist, and free radical scavenger Ginkgo biloba extract, EGb 761, and their combination on reperfusion-induced ventricular fibrillation (VF), ventricular tachycardia (VT), and recovery of cardiac function were studied after 30 min of global ischemia followed by 2 h of reperfusion in isolated rat hearts. In the first series of studies, rats received a daily (oral) dose of 0, 1, 5, 10, 20, or 40 mg/kg/day FK506 for 10 days. FK506 dose-dependently reduced the incidence of reperfusion-induced total (irreversible plus reversible) VF from a value of 92% for untreated animals to 92% (NS), 83% (NS), 67% (NS), 33% (p<0.05), and 25% (p<0.05), for doses of 1-40 mg/kg/day, respectively, with effects on incidence of VT showing the same pattern. FK506, between 20 and 40 mg/kg/day, also resulted in significant recovery of postischemic cardiac function. In the second series of studies, rats were treated with EGb 761 alone or in combination with FK506. Whereas no significant reduction in arrhythmias or improvement in cardiac function resulted from a single intervention of EGb 761 at 25 mg/kg/day, combined treatment of rats with 25 mg/kg/day of EGb 761 and 1 or 5 mg/kg/day of FK506 resulted in a reduction in total and irreversible VF of 92% and 92% to 42% (p<0.05) and 33% (p<0.05), 25% (p<0.05) and 8% (p<0.05), respectively, versus untreated control animals, paralleled by similar effects on the incidence of VT and accompanied by significant improvements in postischemic cardiac function. Our results demonstrate a novel cardioprotective characteristic of FK506 and suggest that combination therapy by using FK506 plus EGb 761 synergistically improves postischemic cardiac function, while reducing the incidence of reperfusion-induced VF and VT, which may expand the clinical utility of FK506 and allow therapy with FK506 at lower doses than are currently useful.
Excellent device performance of 3D In<inf>0.53</inf>Ga<inf>0.47</inf>As gate-wrap-around field-effect-transistors with high-k gate dielectrics (2012)

Excellent device performance of 3D In <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.53</sub> Ga <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.47</sub> As gate-wrap-around field-effect-transistors (GWAFETs) have been demonstrated by a novel device design with innovative fabrication processes. The study of the fabricated 3D In <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.53</sub> Ga <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.47</sub> As GWAFETs with fin width (W <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">fin</sub> ) of 40 nm to 200 nm shows that the device with narrower W <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">fin</sub> exhibits higher drive current, transconductance and better short channel effect (SCE) control. A good combination of current drive and subthreshold characteristics has been achieved by the device with 40 nm W <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">fin</sub> and 140 nm L <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">g</sub> , and it delivers I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">on</sub> of 600 μA/μm at V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">d</sub> =1 V and V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">g</sub> -V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sub> =1 V, subthreshold swing (SS) of 80 mV/dec, and drain induced barrier lowering (DIBL) of 20mV/V. The observed significant improvement in electrostatic control was achieved by our GWA device architecture.