gebhart/patrepeval huggingface dataset:
A hybrid ensemble learning method for tourist route recommendations based on geo-tagged social networks (2018)

Geo-tagged travel photos on social networks often contain location data such as points of interest (POIs), and also users’ travel preferences. In this paper, we propose a hybrid ensemble learning method, BAyes-Knn, that predicts personalized tourist routes for travelers by mining their geographical preferences from these location-tagged data. Our method trains two types of base classifiers to jointly predict the next travel destination: (1) The K-nearest neighbor (KNN) classifier quantifies users’ location history, weather condition, temperature and seasonality and uses a feature-weighted distance model to predict a user’s personalized interests in an unvisited location. (2) A Bayes classifier introduces a smooth kernel function to estimate a-priori probabilities of features and then combines these probabilities to predict a user’s latent interests in a location. All the outcomes from these subclassifiers are merged into one final prediction result by using the Borda count voting method. We evaluated our method on geo-tagged Flickr photos and Beijing weather data collected from 1 January 2005 to 1 July 2016. The results demonstrated that our ensemble approach outperformed 12 other baseline models. In addition, the results showed that our framework has better prediction accuracy than do context-aware significant travel-sequence-patterns recommendations and frequent travel-sequence patterns.
Estimating mental stress using a wearable cardio-respiratory sensor (2010)

This article describes a signal-processing approach to detect mental stress using unobtrusive wearable sensors. The approach addresses a major weakness of traditional methods based on heart-rate-variability (HRV) analysis: sensitivity to respiratory influences. To address this issue, we build a linear model that predicts the effect of breathing on the autonomic nervous system activation, as measured through HRV. Subtraction of respiratory effects leads to a residual signal that provides better discrimination between mental stress and relaxation conditions than traditional HRV tachogram. The method is experimentally validated on a discrimination task with two psycho-physiological conditions: mental stress and relaxation. To illustrate the effectiveness of the method, we impose a pacing respiratory signal that interferes with the main spectral band of the sympathetic branch. Our results suggest that the HRV residual signal has more discrimination power than conventional HRV analysis in the presence of respiration interferences.
Characterization of Densin-180, a New Brain-Specific Synaptic Protein of the<i>O</i>-Sialoglycoprotein Family (1996)

We purified an abundant protein of apparent molecular mass 180 kDa from the postsynaptic density fraction of rat forebrain and obtained amino acid sequences of three tryptic peptides generated from the protein. The sequences were used to design a strategy for cloning the cDNA encoding the protein by polymerase chain reaction. The open reading frame of the cDNA encodes a novel protein of predicted molecular mass 167 kDa. We have named the protein densin-180. Antibodies raised against the predicted amino and carboxyl sequences of densin-180 recognize a 180 kDa band on immunoblots that is enriched in the postsynaptic density fraction. Immunocytochemical localization of densin-180 in dissociated hippocampal neuronal cultures shows that the protein is highly concentrated at synapses along dendrites. The message encoding densin-180 is brain specific and is more abundant in forebrain than in cerebellum. The sequence of densin-180 contains 17 leucine-rich repeats, a sialomucin domain, an apparent transmembrane domain, and a PDZ domain. This arrangement of domains is similar to that of several adhesion molecules, in particular GPIbalpha, which mediates binding of platelets to von Willebrand factor. We propose that densin-180 participates in specific adhesion between presynaptic and postsynaptic membranes at glutamatergic synapses.
Optical Amplifiers in Multiplexed Sensor Systems-Theoretical Pediction of Noise Performance (1996)

The signal to noise ratio of a multiplexed fiber-optic network can be improved by inserting fiber-optic amplifiers. A single preamplifier is the best solution for the network considered. Other configurations may offer practical advantages.
Neuromorphic Character Recognition System With Two PCMO Memristors as a Synapse (2013)

Using memristor devices as synaptic connections has been suggested with different neural architectures in the literature. Most of the published works focus on simulating some plasticity mechanism for changing memristor conductance. This paper presents a neural architecture of a character recognition neural system using Al/Pr <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.7</sub> Ca <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.3</sub> MnO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> (PCMO) memristors. The PCMO memristor has an inhomogeneous barrier at the aluminum and PCMO interface which gives rise to an asymmetrical behavior when moving from high resistance to low resistance and vice versa. This paper details the design and simulations for solving this asymmetrical memristor behavior. Also, a general memory read/write framework is used to describe the running and plasticity of neural systems. The proposed neural system can be produced in hardware using a small 1 K crossbar memristor grid and CMOS neural nodes as presented in the simulation results.
Optimal neuro-controller in longitudinal auto-landing of a commercial jet transport (2004)

In the last three decades, optimality-based auto-landing designs have been considered to the most effective way by many authors. However, it is known that the straight forward solution to the optimal control problem leads to Two Point Boundary Value Problem (TPBVP) (Riccati equation), which is usually too complex in solution, backward in the time, and real-time onboard implementation, or the final time, as a boundary condition, may also not be known precisely. To avoid these problems, first, a suboptimal solution by assuming t/sub f//spl rarr//spl infin/ has been considered and its inapplicability has been discussed. Then an optimal controller for landing phase of a typical commercial aircraft has been designed. Finally, seven neural networks were being trained to learn the costates of the system to estimate the costates in similar scenarios without using the final time value, which usually is needed in solving the optimal control problems.
Novel Lectin-Like Bacteriocins of Biocontrol Strain <i>Pseudomonas fluorescens</i> Pf-5 (2005)

Bacteriocin LlpA, produced by Pseudomonas sp. strain BW11M1, is a peculiar antibacterial protein due to its homology to mannose-binding lectins mostly found in monocots (A. H. A. Parret, G. Schoofs, P. Proost, and R. De Mot, J. Bacteriol. 185:897-908, 2003). Biocontrol strain Pseudomonas fluorescens Pf-5 contains two llpA-like genes, named llpA1(Pf-5) and llpA2(Pf-5). Recombinant Escherichia coli cells expressing llpA1(Pf-5) or llpA2(Pf-5) acquired bacteriocin activity and secreted a 31-kDa protein cross-reacting with LlpA(BW11M1) antibodies. Antibacterial activity of the recombinant proteins was evidenced by gel overlay assays. Analysis of the antimicrobial spectrum indicated that LlpA1(Pf-5) and LlpA2(Pf-5) are able to inhibit P. fluorescens strains, as well as the related mushroom pathogen Pseudomonas tolaasii. LlpA-type bacteriocins are characterized by a domain structure consisting of tandem monocot mannose-binding lectin (MMBL) domains. Molecular phylogeny of these MMBL domains suggests that the individual MMBL domains within an LlpA protein have evolved separately toward a specific, as yet unknown, function or, alternatively, were acquired from different ancestral sources. Our observations are consistent with earlier observations, which hinted that MMBL-like bacteriocins represent a new family of antibacterial proteins, probably with a novel mode of action.
Photoelectrochemical Behavior of Microrod ZnO Coated 316L Stainless Steel Prepared by Hydrothermal Method (2016)

A low-dimensional ZnO film was fabricated on 316L stainless steel (SS) surface by hydrothermal method. Scanning electron microscopy (SEM) showed that the film was consisted of microrods with diameter of about 0.6 μm. X-ray diffraction (XRD) proved the hexagonal phase ZnO of the film. The photoelectrochemical behavior of the microrod ZnO coated electrode was investigated in the presence and absence of UV light irradiation by the open circuit potential (OCP), photocurrent, polarization curve and electrochemical impedance spectrum (EIS) measurements. It was found that the microrod ZnO film exhibited good photo-electrochmical property. The photogenerated current provided noticeable cathodic protection on 316L SS under UV light irradiation. The mechanism of photocurrent cathode protection was discussed.
3D reconstruction for a multi-ring PET scanner by single-slice rebinning and axial deconvolution (1994)

A three-dimensional (3D) image reconstruction method, which was originally developed for a positron emission tomography (PET) system consisting of two rotating scintillation cameras, has now been implemented for a multi-ring PET scanner with retractable septa. The method is called 'single-slice rebinning with axial deconvolution' (SSAD), and can be described as follows. The projection data are sorted into transaxial 2D sinograms. Correction for the axial blurring is made by deconvolution in the sinograms. To obtain the axial spread functions, which depend on the activity distribution, 2D reconstruction is first made using a limited axial acceptance angle. The final 3D image is obtained by 2D reconstruction of transaxial planes. The method is simple but not approximate, has a modest memory requirement, and can be combined with different 2D techniques. Evaluations by Monte Carlo simulations and phantom studies have been made.
Enhanced Raman scattering from cesium suboxides on silver particles and the structure of S-1 photocathodes (1984)

Recent enhanced Raman scattering studies of cesium suboxides in S-1 photocathodes have indicated the presence of Cs11O3 but not Cs2O. The reason for the discrepancy between the currently accepted model of the S-1 and this recent result is discussed.
A synthesis of tetronic acid [furan-2(3H),4(5H)-dione] and three analogues (1972)

A synthesis of four tetronic acids [furan-2(3H),4(5H)-diones] is described. On treatment with triethylamine the readily prepared diethyl α-(chloroacetyl)malonate yielded ethyl 2-ethoxy-4,5-dihydro-4-oxofuran-3-carboxylate (ca. 50%), which was converted into tetronic acid by alkali, and into 3-ethoxycarbonyltetronic acid by water, in high yields. 5-Methyl-, 5-phenyl-, and 5-ethyl-tetronic acids were prepared analogously. The last compound was also obtained by hydrogenation of 5-ethylidenetetronic acid.
Novel computational methods for increasing PCR primer design effectiveness in directed sequencing (2008)

The high-throughput PCR primer design pipeline has been very successful in providing the basis for high-quality directed sequencing results and for minimizing costs associated with labor and reprocessing. The modular architecture of the primer design software has made it possible to readily integrate additional primer critique tests based on iterative feedback from the laboratory. As a result, the primer design software, coupled with the laboratory protocols, serves as a powerful tool for low and high-throughput primer design to enable successful directed sequencing.
Optimization of absorption and multiplication layers characteristics for high performances avalanche photodiodes on silicon and InGaAs/InP heterostructures (2002)

The paper presents a detailed analysis of structure characteristics influence on the performances of avalanche photodiode with multiplication region separates from optical absorption region. SAM-APD on InGaAs/InP heterostructures and reach-through on silicon comparatively, establishing a unified calculation method for the optimum values of the doping levels, the thickness of structure layers and the width of avalanche region.
Synergism Between CryIA Insecticidal Crystal Proteins and Spores of Bacillus thuringiensis, Other Bacterial Spores, and Vegetative Cells Against Lymantria dispar (Lepidoptera: Lymantriidae) Larvae (1995)

The lethality of CryIA(a) and CryIA(c)insecticidal crystal proteins from Bacillus thuringiensis to gypsy moth, Lymantria dispar (L.), was significantly enhanced by the presence of either bacterial spores or vegetative cells of Escherichia coli and several forest epiphytic bacteria. Spores from B. cereus, B. megaterium, and B. subtilis were as effective synergizers of the CryIA insecticidal crystal proteins as spores from an acrystalliferous strain of B. thuringiensis (HD-73 cry−). Klebsiella sp., K pneumonia, Erwinia amylovara, E. rubrifaciens, Pseudomonas fluorescens, Xanthomonas sp., X. campestris, Actinomyces sp. Corynebacterium sp., Flavobacterium sp., and Escherichia coli were effective synergizers of at least one of the CryIA toxins. Only P. syringae was not synergenic. In the absence of the CryIA toxins, none of tile bacterial cell or spore synergists exhibited toxicity or inhibited larval growth or molt to the next instar.
Homo‐ and Copolymerization of <i>ω</i>‐Functional Polystyrene Macromonomers via Coordination Polymerization (2002)

Abstract Macromonomers have been extensively used, as well defined building blocks for various macromolecular architectures via anionic, ROMP and free radical homo‐ or copolymerization processes. The purpose of the present work was to examine the homopolymerization and copolymerization of ω ‐allyl, ω ‐undecenyl and ω ‐vinylbenzyl polystyrene (PS) macromonomers, in the presence of early or late transition metal catalysts. The influence of several parameters (type of catalytic system, nature of polymerizable end‐group and molar mass of the macromonomer) on the homopolymerization was first investigated. Whereas ω ‐allyl or ω ‐undecenyl PS macromonomers were not very reactive in homopolymerization whatever the catalyst, ω ‐vinylbenzyl PS macromonomers gave interesting results with CpTiCl 3 /MAO and Cp*TiCl 3 /MAO. The copolymerization of these macromonomers with ethylene was also studied in the presence of the following palladium catalyst: [(ArNC(Me)C(Me)NAr)Pd(CH 2 ) 3 (COOMe)] + BAr 4 ′ − (VERSIPOL™) (Ar = 2,6‐ i Pr 2 –C 6 H 3 and Ar′ = 3,5‐(CF 3 ) 2 C 6 H 3 ). ω ‐vinylbenzyl PS macromonomers could not be incorporated into poly(ethylene) chains. On the contrary, the incorporation of ω ‐allyl PS macromonomers was achieved. Moreover, for macromonomers containing an alkyl spacer between the allylic unit and the PS chain, the incorporation rate, the copolymerization yield and the molar masses of the copolymers were increased, giving access to a new type of graft copolymer structure. Synthesis of polystyrene macromonomers. magnified image Synthesis of polystyrene macromonomers.
Chromatin structure and gene expression. (1996)

It is now well understood that chromatin structure is perturbed in the neighborhood of expressed genes. This is most obvious in the neighborhood of promoters and enhancers, where hypersensitivity to nucleases marks sites that no longer carry canonical nucleosomes, and to which transcription factors bind. To study the relationship between transcription factor binding and the generation of these hypersensitive regions, we mutated individual cis-acting regulatory elements within the enhancer that lies between the chicken beta- and epsilon-globin genes. Constructions carrying the mutant enhancer were introduced by stable transformation into an avian erythroid cell line. We observed that weakening the enhancer resulted in creation of two classes of site: those still completely accessible to nuclease attack and those that were completely blocked. This all-or-none behavior suggests a mechanism by which chromatin structure can act to sharpen the response of developmental systems to changing concentrations of regulatory factors. Another problem raised by chromatin structure concerns the establishment of boundaries between active and inactive chromatin domains. We have identified a DNA element at the 5' end of the chicken beta-globin locus, near such a boundary, that has the properties of an insulator; in test constructions, it blocks the action of an enhancer on a promoter when it is placed between them. We describe the properties and partial dissection of this sequence. A third problem is posed by the continued presence of nucleosomes on transcribed genes, which might prevent the passage of RNA polymerase. We show, however, that a prokaryotic polymerase can transcribe through a histone octamer on a simple chromatin template. The analysis of this process reveals that an octamer is capable of transferring from a position in front of the polymerase to one behind, without ever losing its attachment to the DNA.
Correction to Alkylated Dihydroxybenzoic Acid as a MALDI Matrix Additive for Hydrophobic Peptide Analysis (2014)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to Alkylated Dihydroxybenzoic Acid as a MALDI Matrix Additive for Hydrophobic Peptide AnalysisYuko Fukuyama*, Ritsuko Tanimura, Kazuki Maeda, Makoto Watanabe, Shin-Ichirou Kawabata, Shinichi Iwamoto, Shunsuke Izumi, and Koichi TanakaCite this: Anal. Chem. 2014, 86, 10, 5187Publication Date (Web):May 8, 2014Publication History Published online8 May 2014Published inissue 20 May 2014https://pubs.acs.org/doi/10.1021/ac501498nhttps://doi.org/10.1021/ac501498ncorrectionACS PublicationsCopyright © 2014 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views561Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (107 KB) Get e-Alertsclose Get e-Alerts
Spectrum-sliced, 25-GHz spaced, 155 Mbps×32 channel WDM access (2002)

We estimated the BER performance of spectrum-sliced WDM access influenced by adjacent crosstalk numerically and experimentally. The BER performance was improved as the spectral width was widened, while it was degraded by the crosstalk as the spectral width approached the channel spacing. We derived the optimum spectral width as 14 GHz at a channel spacing of 25 GHz and a bit rate of 155 Mbps, and the BER was estimated to be less than 10/sup -15/ between 12 to 16 GHz. The transmission performance was also measured by experiments using 15-GHz wide, 25-GHz channel-spaced, 155-Mbps /spl times/ 32-channel transmissions through 50-km of DSF, and showed good agreement with the calculated results.
Universes Collide: Combining Immunotherapy with Targeted Therapy for Cancer (2014)

Two major advances in melanoma have occurred concurrently and involve treatment with targeted therapy and immune checkpoint blockade. However, each of these approaches has limitations with regard to overall response rates or duration of response. To address this, investigators have proposed combining these strategies, and this concept is being tested empirically in clinical trials. There is a scientific rationale supporting the combination of targeted therapy and immunotherapy, and these concepts are discussed herein.
The type‐III Fe receptor from <i>Streptococcus dysgalactiae</i> is also an α<sub>2</sub>‐macroglobulin receptor (1994)

We have cloned and sequenced the gene for a type‐III Fe receptor from a Streptococcus dysgalactiae strain isolated from bovine mastitis and report here the complete sequence of the gene. The 1992‐nucleotides‐long open reading frame codes for a protein of 664 amino acids with a predicted molecular mass of 72 kDa (including the signal peptide). The C‐terminal part of the protein is very similar to other streptococcal type‐III receptors but contains five homologous IgG‐binding domains compared to two or three in earlier reported Fe receptors of this type. Upstream of the IgG‐binding domains, there is a unique sequence containing short repeated motifs. Subeloning different parts of the gene and expressing them as maltose‐binding fusion proteins revealed that the upstream part is mediating binding to the plasma proteinase inhibitor α 2 ‐macroglobulin after its complex formation with proteases. In contrast to earlier described type‐III Fe receptors, this molecule does not bind human serum albumin.
Fluorescent Bisphosphonate and Carboxyphosphonate Probes: A Versatile Imaging Toolkit for Applications in Bone Biology and Biomedicine (2015)

A bone imaging toolkit of 21 fluorescent probes with variable spectroscopic properties, bone mineral binding affinities, and antiprenylation activities has been created, including a novel linking strategy. The linking chemistry allows attachment of a diverse selection of dyes fluorescent in the visible to near-infrared range to any of the three clinically important heterocyclic bisphosphonate bone drugs (risedronate, zoledronate, and minodronate or their analogues). The resultant suite of conjugates offers multiple options to "mix and match" parent drug structure, fluorescence emission wavelength, relative bone affinity, and presence or absence of antiprenylation activity, for bone-related imaging applications.
Uniform Solute Deposition of Evaporable Droplet in Nanoliter Wells (2007)

<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> There have been many microdeposition processes that are based on the evaporation of nanoliter-sized droplets, such as inkjet printing, deoxyribonucleic acid/protein microarrays, or lithography direct writing. However, it is important but still difficult to control the uniformity of the solute deposition from a nanoliter sessile droplet on a plane substrate. This paper proposes a method for uniform solute deposition from evaporable droplet by confining the droplet with rib structures (wells) of specific surface properties. The hydrodynamic process was experimentally investigated and analyzed in detail. Surface wettability on the well surface is verified to be critical for controlling a droplet as a flat film inside a well during evaporation to minimize horizontal solute transfer for uniform solute deposition. Pure water and water/tracing particle mixture (2.57% solid latex, dyed blue) were employed for the test. The results demonstrated that a 97% uniformity is obtained for the solute deposited from a 37-nL droplet in a well with hydrophobic surface (contact angle of 100<formula formulatype="inline"><tex>$^{\circ}$ </tex></formula>), whereas a 31% uniformity is obtained for a more hydrophilic surface (contact angle of 25 <formula formulatype="inline"><tex>$^{\circ}$</tex></formula>). The higher hydrophobicity (contact angle above 90 <formula formulatype="inline"><tex>$^{\circ}$</tex></formula>) on the well surface yields a flatter profile of film during droplet evaporation inside a well and, thus, promotes a more uniform deposition of the solute. <formula formulatype="inline"><tex>$\hfill$</tex></formula>[2006-0194] </para>