gebhart/patrepeval huggingface dataset:
Status, Utilization and Economic Valuation of Non-timber Forest Products of Arunachal Pradesh, India (2015)

Non-timber forest products are important component of subsistence and livelihood of tribal communities living in and near forests. This is of particular significance in the state of Arunachal Pradesh having more than 80% of geographical area under forest cover and predominantly inhabited by tribal people. Purpose of this study was to document the status and utilization pattern and to assess the economic value of NTFPs of the state. Present study was carried out in eight districts of Arunachal Pradesh viz., Changlang, East Kameng, Lower Subansiri, Tawang, Tirap, Upper Siang, West Kameng and West Siang covering 34 villages and 350 households. Altogether, 135 plant based and 36 animal based non-timber forest products were recorded. Among plant based NTFPs, 54 species were collected for leaves, 30 for stem and 22 for fruits. Most of the animal based NTFPs (93%) were collected/hunted for food. Average 20~40 kg of NTFPs was collected annually per household. Maximum plant based NTFP collection was recorded from West Siang followed by West Kameng and Tawang. Similarly, highest collection of animal based NTFPs was recorded from West Siang followed by Tirap and Lower Subansiri. NTFP contributed more than 50% of annual income of the people of East Kameng, Tirap, Lower Subansiri and Upper Siang districts. An illiterate and unemployed person with minimum agricultural land was more dependent on forests for his livelihood than a literate jobholder. The study concludes that a large section of people of Arunachal Pradesh are dependent on NTFPs for their livelihood however due to its unscientific harvesting, the availability of NTFPs is receding with time. There is an urgent need to promote cultivation and scientific harvesting of NTFPs in order to conserve the plant and animal diversity of this global biodiversity hotspot and for ensuring livelihood security of the people living in this area.
Reliability of clinician judgements of bruxism (2003)

Bruxism is considered to be a parafunctional disorder requiring treatment and is viewed as a risk factor for the development of temporomandibular disorders (TMDs). The purpose of this investigation is to examine the reliability of clinician judgements of bruxism severity. Twenty dentists who are faculty members in a dental school examined 29 stone casts and gold-plated models of individual teeth for evidence of bruxism. Ordinal ratings of bruxism severity for the 29 augmented models were made on two occasions, approximately 3 months apart. Inter-rater reliability among all clinicians, evaluated using intraclass correlation coefficients (ICCs), was poor at both time one and time two (i.e. ICC = 0.33 and 0.32, respectively), with somewhat better reliability found among those clinicians with above-average time elapsed since completion of dental training (i.e. ICC = 0.48 and 0.50 for time 1 and time 2, respectively). Three-month test-retest reliabilities were fair (ICC = 0.46) for the full group of raters and were unrelated to clinicians' degree of confidence in their ratings. These results indicate a need to standardize methods for clinical assessment of bruxism. Additionally, they have implications for studies using clinical assessments of bruxism to test the association between bruxism and other conditions such as TMDs.
Inducible Expression of Manganese Superoxide Dismutase by Phorbol 12-Myristate 13-Acetate Is Mediated by Sp1 in Endothelial Cells (2000)

The expression of manganese superoxide dismutase (Mn-SOD), an important component of the cellular defense system against oxidative stress, is induced in response to a variety of stimuli, including cytokines and phorbol esters, in endothelial cells. To define the molecular mechanisms regulating the expression of Mn-SOD, we have characterized the promoter of the human Mn-SOD gene. In calf pulmonary artery endothelial cells, phorbol 12-myristate 13-acetate (PMA) gradually increased Mn-SOD mRNA levels, with a peak at 6 to 12 hours after stimulation. The increase in Mn-SOD mRNA was significantly inhibited by a protein kinase C (PKC) inhibitor (calphostin C) but not by a mitogen-activated protein kinase kinase-1 inhibitor (PD98059) or a p38 mitogen-activated protein kinase inhibitor (SB203580). By reporter gene transfection experiments of a series of promoter deletions and site-directed mutation constructs, we found 2 consensus Sp1 binding sequences located at -97 and at -77 to play an important role in PMA-induced Mn-SOD transcription. Electrophoretic gel mobility shift assays have indicated that this sequence serves as an Sp1 binding site. Northern and Western blot analysis has revealed that PMA-induced promoter activity of Mn-SOD correlates with an increased expression of Sp1. Nuclear proteins from PMA-treated calf pulmonary artery endothelial cells displayed an increased DNA binding to the Sp1 site. Furthermore, the Mn-SOD promoter was activated either by overexpression of Sp1 or the constitutively activated form of PKCbeta in an Sp1 site-dependent manner. These results suggest that PMA stimulates transcription of the Mn-SOD gene through an increase in Sp1 expression and thus implicate Sp1 as an effector mediating the PKC-signaling pathway elicited by extracellular signals.
24.4 Sandwich-RAM: An Energy-Efficient In-Memory BWN Architecture with Pulse-Width Modulation (2019)

Convolutional neural networks (CNN) achieve state-of-the-art results in the field of visual perception, drastically changing the traditional computer-vision framework. However, the movement of massive amounts of data prevents CNN’s from being integrated into low-power IoT devices. The recently proposed binaryweight network (BWN) reduces the complexity of computation and amount of memory access. A conventional digital implementation, which is composed of separate feature/weight memories and a multiply-and-accumulate (MAC) unit, requires large amounts of data to be moved [3]. To reduce power the weight memory and the computations are integrated together, into an in-memory computation architecture [1, 2, 5]. However, feature data is still stored externally, so data movement has only been partially addressed, especially for BWN. This paper blends feature and partial-weight memory with a computing circuit together, like a sandwich, that achieves significantly less data access (Fig. 24.4.1). It also uses a reconfigurable analog-computation engine, based on pulse-width modulation, that is small and flexible enough to be inserted into the memory.
Relationship between Anti-Pasteurella multocida Antibody Titers after CU Vaccination and Survival after Challenge (1989)

The relationship between serum anti-Pasteurella multocida antibodies and survival rates after challenge was determined in turkeys vaccinated one or more times with the live avirulent Clemson University (CU) vaccine and then challenged with a virulent isolate (9481) of P. multocida in the drinking water. A microtiter agglutination test for assaying anti-P. multocida serum antibodies demonstrated a highly significant (P less than 0.001) correlation between the serum antibody titer 1 week after the initial or single vaccination and the survival rate after challenge, and a significant (P less than 0.01) correlation between the antibody titer immediately before challenge and the survival rate after challenge. A highly significant (P less than 0.0001) correlation was also observed between the antibody titer before vaccination and the survival rate after challenge. This relationship was considered the result of an anamnestic response by the CU vaccine to a previous sensitization by antigens of other microbial organisms, probably in the intestine and similar antigenically to P. multocida. In contrast, a significant (P less than 0.05) but negative correlation was seen between the antibody titer 1 week after challenge and the survival rate. This relationship was thought to be the result of a marked stimulation of the antibody titer by the systemic infection of P. multocida that subsequently killed the turkeys.
"Formas y colores: la ilustración infantil en España" de Jaime García Padrino (2004)

Considering that nearly two thirds of the CTCL patients treated with alitretinoin showed a response or stable disease, together with a low number of side effects and low cost compared to bexarotene, alitretinoin may be a potential alternative in the treatment of less advanced CTCLs. This survey represents the largest number of recorded therapies with the retinoid alitretinoin in CTCLs in a European patient collective.
Distributed caching and adaptive search in multilayer P2P networks (2004)

To improve the scalability of Gnutella-like unstructured peer-to-peer (P2P) networks, a uniform index caching (UIC) mechanism was suggested in some earlier work. In UIC, query results are cached in all peers along the inverse query path such that the same query of other peers can be replied from their nearby-cached results. However, our experiments show that the UIC method causes a large amount of duplicated and unnecessary caching of items among neighboring peers. Aiming at improving the search efficiency, we propose a distributed caching mechanism, which distributes the cache results among neighboring peers. Furthermore, based on the distributed caching mechanism, an adaptive search approach is built which selectively forwards the query to the peers with a high probability of providing the desired cache results. All the enhancements above are defined in a protocol called distributed caching and adaptive search (DiCAS). In the DiCAS enhanced Gnutella network, all the peers are logically divided into multiple layers, with the character that all the peers in the same layer have the same group ID. The query flooding is restricted in one layer with the matched group ID. Our simulation study shows that, with the help of the index caching and search space division, the DiCAS protocol can significantly reduce the network search traffic in unstructured P2P systems without degrading query success rate.
Memory in the fast lane (1994)

The author describes how the demand for higher-bandwidth memories in systems from multiprocessing to multimedia has designers pulling out all the stops. Topics discussed include: cache hierarchy; rapider RAM; wider data; application specific DRAMs; synchronous memories; and SRAM caches.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Evaluation of human peripheral blood leukocytes for mast cell tryptase. (1987)

Murine monoclonal and goat polyclonal antibodies against tryptase, the dominant neutral protease and protein component in secretory granules of human mast cells, were used to assess the presence of tryptase in peripheral leukocytes. Carnoy's fluid-fixed cytocentrifuge preparations of enriched populations of lymphocytes, monocytes, eosinophils, and neutrophils showed no reactivity with anti-tryptase antibodies by a sensitive indirect immunoperoxidase procedure. Dispersed human lung mast cells showed strong granular cytoplasmic staining with both antibodies, whereas only approximately 50% of the peripheral blood basophils detectable with Wright's stain were detected with anti-tryptase antibodies, and these showed a staining pattern that was faint, granular, and cytoplasmic at high concentrations of antibody. At lower antibody concentrations mast cell staining was still intense, whereas basophils were not stained. Extracts of neutrophils and lymphocytes of up to 90% purity had undetectable amounts of tryptase by an ELISA sandwich immunoassay, as well as undetectable enzymatic activity with tosyl-L-gly-pro-lys-p-nitroanilide (a sensitive substrate for tryptase) in the presence of soybean trypsin inhibitor. Extracts of basophil-enriched (6 to 50% purity) preparations contained 0.046 +/- 0.013 pg of tryptase per basophil by the immunoassay along with 2 X 10(-9) +/- 0.8 X 10(-9) U of tryptase-like enzyme activity per basophil, compared with corresponding values of 12 pg, 480 X 10(-9) U of tryptase per human lung mast cell. Thus very small amounts of tryptase are present in human basophils (approximately 0.4% of that found in mast cells), but not in other peripheral leukocytes.
Radar coverage predictions through time- and range-dependent refractive atmospheres with planetary boundary layer and electromagnetic parabolic equation models (2002)

The enhancement of the capability of electromagnetic parabolic equation (EMPE) and other propagation codes by using predictions from an atmospheric forecast model to provide refractivity data for range-dependent and time-varying situations is demonstrated. Starting from measured temperature and humidity data at one location and time, the JHU/APL planetary boundary layer model is used to obtained predictions for a 24-h forecast period. Predicted fields of temperature, humidity, and refractivity after 12 and 24 h are compared with measured data to verify the forecast, and vertical profiles of refractivity for each hour are provided, along with appropriate radar parameters, as input to EMPE. The EMPE calculations of expected radiation patterns as functions of height and range at selected times demonstrate the effects of hourly changes in the structure of the lower atmosphere on radar propagation. The radar propagation calculations have been repeated using the IREPS code to illustrate the similarities and differences between the two models when applied to this somewhat idealized, horizontally homogeneous situation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Synthesis and Water Solubility of Novel Fullerene Bisadduct Derivatives (2003)

Abstract The synthesis of four classes of bisadduct derivatives of C 60 is reported. The solubility of the new compounds in aqueous solvents is enhanced and is among the highest ever reported for fullerene derivatives. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)
Electroantennogram responses of the carrot fly, <i>Psila rosae</i> , to volatile plant components (1980)

ABSTRACT. Electroantennogram (EAG) responses of male and female carrot flies, Psila rosae F. (Diptera: Psilidae), were recorded to thirty‐six volatile plant constituents. The most distinct EAG responses were obtained to: (1) the general green leaf volatiles 1‐hexanol, trans‐2‐hexen‐1‐ol and cis‐3‐hexen‐1‐ol, their isomers cis‐2‐hexen‐1‐ol and trans‐3‐hexen‐1‐ol, the alcohol 1‐heptanol, the ester cis‐3‐hexenyl acetate and the leaf aldehydes hexanal and trans‐2‐hexenal, and (2) from four compounds associated with the umbelliferous host plants of this insect, namely trans‐methyl‐iso‐eugenol, β‐caryophyllene, linalool and trans‐2‐nonenal. Higher responses were elicited by the leaf aldehydes than by the corresponding alcohols. Although the absolute amplitude of the female response was over twice that of the male, there were no differences between the relative responses to the compounds tested in both sexes, with the exception of a much higher response to the leaf aldehydes in the male. The shape of the EAG evoked by the various compounds was consistently different, with the slowest recovery being recorded for trans‐methyl‐iso‐eugenol. While the antennal olfactory receptors of the carrot fly are sensitive to the closely related general green leaf volatiles, they are most specifically tuned to the aldehyde component of this green odour complex. In addition, the ability of this insect to discriminate between different plants may be augmented by the perception of a group of more host specific volatiles. The conformity of the responses of males and females to the compounds tested may indicate that host plant volatiles plays an additional role as an aggregation cue for both sexes.
International volunteering: today's opportunities for professionals and executives. (1997)

Are you counseling others who's jobs have changed? Are you looking for something different yourself? This author who recruits professionals for international projects has found an increase in interest by professionals in taking international assignments. This article describes what opportunities are available and how to find them.
A new approach for the construction of ALM trees using layered video coding (2005)

This paper presents a novel approach for efficient tree construction in ALM (Application Layer Multicast) using layered video coding. This mechanism is suitable for the users in heterogeneous environment such as xDSL and CATV, where upload and download speeds are different. We point out some problems in these environments of the ALM and show their solutions at two stages. First, we redefine the parameter which originally specifies the number of single rate streams the host can transmit, to reflect asymmetric link properties and to accommodate layered streams. Second, we develop an efficient tree construction algorithm using the renewed degree parameter, which maximizes total throughput of all hosts. Simulations using NS-2 prove improvement in throughput, delay and overhead by our proposal. Software implementation is also carried out, and subjective quality improvement is verified.
Potential use of alexidine dihydrochloride as an apoptosis-promoting anticancer agent (2006)

Despite advances in surgery, radiation, and chemotherapy, novel therapeutics are needed for head and neck cancer treatment. The objective of this current study was to evaluate alexidine dihydrochloride as a novel compound lead for head and neck cancers. Using a tetrazolium-based assay, the dose required to reduce cell viability by 50% (ED50) was found to be approximately 1.8 micromol/L in FaDu (human hypopharyngeal squamous cancer) and approximately 2.6 micromol/L in C666-1 (human undifferentiated nasopharyngeal cancer) cells. In contrast, the ED50 values were much higher in untransformed cells, specifically at approximately 8.8 micromol/L in GM05757 (primary normal human fibroblast), approximately 8.9 micromol/L in HNEpC (primary normal human nasal epithelial), and approximately 19.6 micromol/L in NIH/3T3 (mouse embryonic fibroblast) cells. Alexidine dihydrochloride did not interfere with the activities of cisplatin, 5-fluorouracil, or radiation, and interacted in a less-than-additive manner. DNA content analyses and Hoechst 33342 staining revealed that this compound induced apoptosis. Alexidine dihydrochloride-induced mitochondrial damage was visualized using transmission electron microscopy. Mitochondrial membrane potential (DeltaPsiM) depolarization was detectable after only 3 hours of treatment, and was followed by cytosolic Ca2+ increase along with loss of membrane integrity/cell death. Caspase-2 and caspase-9 activities were detectable at 12 hours, caspase-8 at 24 hours, and caspase-3 at 48 hours. FaDu cell clonogenic survival was reduced to < 5% with 1 micromol/L alexidine dihydrochloride, and, correspondingly, this compound decreased the in vivo tumor-forming potential of FaDu cells. Thus, we have identified alexidine dihydrochloride as the first bisbiguanide compound with anticancer specificity.
Pixels Consisting of Double Vertical-Cavity Detector and Single Vertical-Cavity Laser Sections for 2-D Bidirectional Optical Interconnections (1992)

1992 International Conference on Solid State Devices and Materials,Pixels Consisting of Double Vertical-Cavity Detector and Single Vertical-Cavity Laser Sections for 2-D Bidirectional Optical Interconnections
Needle Biopsy of Intracranial Lesions Guided by Computerized Tomography (1979)

Biopsies can be performed directly with computerized tomography (CT) head scanners with some difficulty. The small scanning orifice does not allow enough room for needle placement; therefore, biopsy is difficult. In contrast, the scanning orifice of the CT body scanner is large enough to permit biopsies without hindrance. Over 300 CT-guided abdominal biopsy procedures have been performed at the Cleveland Clinic Foundation. We are reporting the technique and the results of 14 CT-guided brain biopsies. There were no complications in the series and an accurate diagnosis was made for 13 of the 14 patients.
Magnetic electrostatic plasma confinement (1994)

Electrostatic plasma confinement and magnetic electrostatic plasma confinement (MEPC) have been studied for four decades. The multiple potential well hypothesis, postulated to explain high neutron yields from Hirsch's colliding beam experiment (1968), has been supported by several pieces of evidence, but results were inconclusive. Magnetic shielding of the grid was developed to reduce the required beam current and to prevent grid overheating. Electrostatic plugging of magnetic cusps evolved to a similar configuration. Due to low budgets, early MEPC experiments used spindle cusps, which are poor for plasma confinement. Later experiments used multipole cusps or a linear set of ring cusps, which have larger volumes of field-free plasma. To keep the self-shielding voltage drop Delta phi <or=100 kV, the electron density na in the anode gap should be less than about 1019 m-3. The central plasma density can be an order of magnitude higher. The ATOLL toroidal quadrupole had anomalous electron energy transport, but the Jupiter-2M linear set of ring cusps achieved a transport rate about a factor of two above the classical rate. With near-classical transport, a power gain ratio Q approximately=10 is predicted for a reactor with rp=3m, Ba=6T, and applied voltage phi A=400 kV. Besides producing electricity and synthetic fuels, MEPC reactors could be used for heavy ion beams sources and neutron generators. The main issues of concern for MEPC reactor development are electron transport, plasma purity and electrode alignment and voltage holding.
Relative and absolute quantitative expression profiling of cytochromes P450 using isotope‐coded affinity tags (2006)

The development of a novel method for absolute quantification of proteins based on isotope-coded affinity tagging using ICAT reagents is described. The method exploits synthetic peptide standards to determine protein content at the femtomole level in biological samples. The approach is generally applicable to any subset of proteins, but is particularly appropriate for quantitative analysis of multiple, closely related isoforms, and for hydrophobic proteins that are poorly represented in 2-D gels. Relative and absolute quantification techniques are applied to an important group of microsomal metabolic enzymes, the cytochromes P450 (P450), which are critical in determining the disposition, safety and efficacy of drugs in man. Measurement of the P450 induction profile in response to chemicals is a fundamental aspect of drug safety evaluation and is currently achieved by low-throughput methods employing poorly discriminatory antibodies or substrates. Tagging technology is shown to supersede conventional methods for P450 profiling in terms of discriminatory power and throughput, exemplified by the simultaneous detection of distinct induction profiles for cyp2c subfamily members in response to phenobarbitone: cyp2c29 expression, but not cyp2c40 or cyp2c50, was induced threefold by treatment. This technology should abbreviate the drug development pathway, and provide a widely applicable, rapid means of quantifying proteins.