gebhart/patrepeval huggingface dataset:
Pulse shaping filter design in uwb system (2004)

This article develops an optimal pulse shaping filter design framework, which minimizes UWB signal interference to existing (or legacy) narrow band signals, such as global positioning system (GPS), satellite communication systems, etc. A 2-stage optimal filter design procedure is proposed. In the first stage, a transmission filter is optimized to satisfy an imposed transmission mask, which minimizes UWB interference to a tolerable level. In the sub-sequent optimization stage, a recovery filter is optimized to best recover the transmitted signal. The effectiveness of this procedure is demonstrated with an example, in which FCC indoor transmission spectral mask is used to design the transmission filter. This procedure makes it possible to best recover the transmitted signal while minimizing the UWB interference to other legacy systems.
Miscibility of poly(styrene-co-acrylonitrile) and poly(α-methyl styrene-co-acrylonitrile) with polymethacrylates containing sterically hindered amine groups (1987)

Sterically hindered amine groups were incorporated into poly(methy1 methacrylate) and poly(ethy1 methacrylate) by copolymerizing 2,2,6,6 tetramethylpiperidinyl methacrylate (TPMA) with MMA and EMA. The replacement of the pendant alkyl groups of the polymethacrylates by SHA groups reduced their miscibility with poly(styrene-co-acrylonitrile) (SAN) and with poly(α-methyl styrene-co-acrylonitrile) (MSAN). The cloud points of the miscible blends indicated that the effective interaction parameter B of a blend became less negative with increasing TPMA content in the copolymer, and B was more negative for SAN blend than for a corresponding MSAN blend.
Presence of parasite antigen on the surface of P388D1 cells infected with Ehrlichia risticii (1992)

Indirect immunofluorescence staining of macrophages infected with Ehrlichia risticii by anti-E. risticii serum revealed a punctate staining pattern on the surface of the host cell. This pattern was distinguishable by fluorescence microscopy from E. risticii bound to the surface of the macrophage and from intracellular E. risticii. The surface localization of ehrlichial antigen on infected macrophages was confirmed by electron microscopy with immunoferritin labeling. As the intracellular ehrlichial burden increased, the amount of ehrlichial antigen on the host cell surface increased. Prokaryotic protein synthesis was necessary for the maintenance of ehrlichial antigen on the host cell surface, as demonstrated by disappearance of the surface antigen following treatment with oxytetracycline. However, host cell protein synthesis was not required, as demonstrated by the continued presence of ehrlichial antigen on the surface of host cells after cycloheximide treatment. Pronase treatment abolished the ehrlichial antigen present on the cell surface, indicating that this antigen is a protein. Anti-E. risticii serum or immunoglobulin G-mediated antibody-dependent cellular cytotoxicity of infected cells was demonstrated in a chromium release assay. These results imply that the parasite antigen on the host cell surface has a role in the pathogenesis of ehrlichiosis.
Internet-Based Design Visualization for Layered Manufacturing (2003)

When considering the use of layered manufacturing (LM), there are many issues a designer has to address for handling a stereolithography tessellation language (STL) model, the de facto standard for LM. In this paper, we propose an Internet-based design visualization tool for decision support when optimizing the LM process in support of a highly interactive and collaborative virtual environment between CAD designers and LM processes over networks. It directly provides designers with an advanced preprocessor functionality, design visualization/optimization, as well as model display, repair, and slicing over the network. This can help smooth data transfer from CAD to the LM process with minimum inconsistency in CAD data.
Single-exposure multiphoton fabrication of polygonized structures by an SLM-modulated Fresnel zone lens (2016)

Recently, annular beams have been developed to rapidly fabricate microscope tubular structures via two-photon polymerization, but the distribution of the light field is limited to a ring pattern. Here a Fresnel lens is designed and applied to modulate the light field into a uniform quadrangle or hexagon shape with controllable diameters. By applying a spatial light modulator to load the phase information of the Fresnel lens, quadrangle and hexagon structures are achieved through single exposure of a femtosecond laser. A 3×6 array of structures is made within 9 s. Comparing with the conventional holographic processing, this method shows higher uniformity, high efficiency, better flexibility, and easy operation. The approach exhibited a promising prospect in rapidly fabricating structures such as tissue engineering scaffolds and variously shaped tubular arrays.
Antioxidant therapy for treatment of inflammatory bowel disease: Does it work? (2015)

Oxidative stress (OS) is considered as one of the etiologic factors involved in several signals and symptoms of inflammatory bowel diseases (IBD) that include diarrhea, toxic megacolon and abdominal pain. This systematic review discusses approaches, challenges and perspectives into the use of nontraditional antioxidant therapy on IBD, including natural and synthetic compounds in both human and animal models. One hundred and thirty four papers were identified, of which only four were evaluated in humans. Some of the challenges identified in this review can shed light on this fact: lack of standardization of OS biomarkers, absence of safety data and clinical trials for the chemicals and biological molecules, as well as the fact that most of the compounds were not repeatedly tested in several situations, including acute and chronic colitis. This review hopes to stimulate researchers to become more involved in this fruitful area, to warrant investigation of novel, alternative and efficacious antioxidant-based therapies.
Thapsigargin causes Ca2+ release and collapse of the membrane potential of Trypanosoma brucei mitochondria in situ and of isolated rat liver mitochondria. (1993)

Thapsigargin, previously reported to release Ca2+ from non-mitochondrial stores of different cell types, as well as nigericin, were found, when used at high concentrations, to release Ca2+ and collapse the membrane potential of Trypanosoma brucei bloodstream and procyclic trypomastigotes mitochondria in situ. At similarly high concentrations (> 10 microM), thapsigargin was also found to release Ca2+ and collapse the membrane potential of isolated rat liver mitochondria. These results indicate that care should be taken when attributing the effects of thapsigargin in intact cells to the specific inhibition of the sarcoplasmic and endoplasmic reticulum Ca(2+)-ATPase family of calcium pumps. In addition, we have found no evidence for an increase in intracellular Ca2+ by release of the ion from intracellular stores by nigericin, measuring changes in cytosolic Ca2+ by dual wavelength spectrofluorometry in fura-2-loaded T. brucei bloodstream trypomastigotes or measuring Ca2+ transport in digitonin-permeabilized cells.
The Perception of Subjective Surfaces (1981)

It is proposed that subjective contours are an artifact of the perception of natural three-dimensional surfaces. A recent theory of surface interpolation implies that "subjective surfaces" are constructed in the visual system by interpolation between three-dimensional values arising from interpretation of a variety of surface cues. We show that subjective surfaces can take any form, including singly and doubly curved surfaces, as well as the commonly discussed fronto-parallel planes. In addition, it is necessary in the context of computational vision to make explicit the discontinuities, both in depth and in surface orientation, in the surfaces constructed by interpolation. It is proposed that subjective surfaces and subjective contours are demonstrated. The role played by figure completion and enhanced brightness contrast in the determination of subjective surfaces is discussed. All considerations of surface perception apply equally to subjective surfaces.
Creating and sharing personalized time-based annotations of videos on the web (2010)

This paper introduces a multimedia document model that can structure community comments about media. In particular, we describe a set of temporal transformations for multimedia documents that allow end-users to create and share personalized timed-text comments on third party videos. The benefit over current approaches lays in the usage of a rich captioning format that is not embedded into a specific video encoding format. Using as example a Web-based video annotation tool, this paper describes the possibility of merging video clips from different video providers into a logical unit to be captioned, and tailoring the annotations to specific friends or family members. In addition, the described transformations allow for selective viewing and navigation through temporal links, based on end-users' comments. We also report on a predictive timing model for synchronizing unstructured comments with specific events within a video(s). The contributions described in this paper bring significant implications to be considered in the analysis of rich media social networking sites and the design of next generation video annotation tools.
The effects of expiratory positive airway pressure on functional residual capacity in normal subjects (1978)

Functional residual capacity (FRC) was determined by constant volume, whole body plethysmography in seven normal subjects under resting conditions and following the addition of increasing levels of expiratory positive airway pressure (EPAP). There was a significant increase in FRC in six of the seven subjects studied. Grouped data showed a progressive increase in FRC with increasing EPAP (p less than 0.01). The highest level of EPAP (15 cm H2O) was associated with a 20% increase in FRC. We have been able to confirm that EPAP provides a simple and effective method of increasing FRC which could be applied to the treatment of conditions characterized by temporary and reversible reduction in lung volume.
PMMA denture base material enhancement: a review of fiber, filler, and nanofiller addition (2017)

This paper reviews acrylic denture base resin enhancement during the past few decades. Specific attention is given to the effect of fiber, filler, and nanofiller addition on poly(methyl methacrylate) (PMMA) properties. The review is based on scientific reviews, papers, and abstracts, as well as studies concerning the effect of additives, fibers, fillers, and reinforcement materials on PMMA, published between 1974 and 2016. Many studies have reported improvement of PMMA denture base material with the addition of fillers, fibers, nanofiller, and hybrid reinforcement. However, most of the studies were limited to in vitro investigations without bioactivity and clinical implications. Considering the findings of the review, there is no ideal denture base material, but the properties of PMMA could be improved with some modifications, especially with silanized nanoparticle addition and a hybrid reinforcement system.
Phosphorylation of sucrose synthase at serine 170: occurrence and possible role as a signal for proteolysis (2003)

Sequence analysis identified serine 170 (S170) of the maize (Zea mays L.) SUS1 sucrose synthase (SUS) protein as a possible, second phosphorylation site. Maize leaves contained two calcium-dependent protein kinase activities and a calcium-independent kinase activity with characteristics of an sucrose non-fermenting 1 (SNF1)-related protein kinase. Phosphorylation of the novel S170 and the known serine 15 (S15) site by these protein kinases was determined in peptide substrates and detected in SUS1 protein substrates utilizing sequence- and phosphorylation-specific antibodies. We demonstrate phosphorylation of S170 in vitro and in vivo. The calcium-dependent protein kinases phosphorylated both S170 and S15, whereas SNF1-related protein kinase activity was restricted to S15. Calcium-dependent protein-kinase-mediated S170 and S15 phosphorylation kinetics were determined in wild-type and mutant SUS1 substrates. These analyses revealed that kinase specificity for S170 was threefold lower than that for S15, and that phosphorylation of S170 was stimulated by prior phosphorylation at the S15 site. The SUS-binding peptides encoded by early nodulin 40 (ENOD40) specifically antagonized S170 phosphorylation in vitro. A model wherein S170 phosphorylation functions as part of a mechanism targeting SUS for proteasome-mediated degradation is supported by the observations that SUS proteolytic fragments: (i) were detected and possessed relatively high phosphorylated-S170 (pS170) stoichiometry; (ii) were spatially coincident with proteasome activity within developing leaves; and (iii) co-sedimented with proteasome activity. In addition, full-length pS170-SUS protein was less stable than S170-SUS in cultured leaf segments and was stabilized by proteasome inhibition. Post-translational control of SUS protein level through pS170-promoted proteolysis may explain the specific and significant decrease in SUS abundance that accompanies the sink-to-source transition in developing maize leaves.
Gastrokinetic effects of levosulpiride in dyspeptic patients with diabetic gastroparesis. (1995)

Our study first demonstrates that levosulpiride has an accelerating effect on the emptying of solids from the stomach of patients with diabetic gastroparesis. The drug is also effective in relieving upper gastrointestinal symptoms in patients whose gastric emptying times remain very slow. Our findings suggest, but do not prove, that better blood glucose control could be achieved with reduction of gastric emptying time; further trials are needed in this field.
Test de VPH (captura de híbridos II) en pacientes tratadas con radiofrecuencia (2012)

Introduction: Human papillomavirus (HPV) is the virus most commonly transmitted through sex. There are methods for detecting molecular biology of this virus. According to the Mexican Official Standard NOM-014-SSA2-1994, molecular tests such as Hybrid Capture and PCR be used as an adjunct to cytology in both the screening and in follow-up after six months after the management. Objective: To determine the percentage of negative HPV test in women treated for preinvasive lesions of the cervix in the Colposcopy Service at the Hospital of Gynecology and Obstetrics, Maternal and Child Health Institute of Mexico State. Material and methods: We included patients with preinvasive lesions of the cervix treated with radiofrequency. At six months were asked HPV test (Hybrid Capture II). Cervical sample was obtained by QUIAGINE Cervical Sampler colposcopically visible in the lesion or defect in the processing area where the injury was. Once processing is performed release and denaturation of nucleic acids. Results: We studied 80 patients with preinvasive lesions of the cervix treated with radiofrequency. Negativization HPV DNA Test HCII at six months was 91.25%. Conclusions: The percentage of negative HPV test achieved in our research is within the accepted level in international standards. Further studies are needed that focus on this issue.
An Improved Image Segmentation Algorithm Based on the Otsu Method (2012)

By analyzing the basic principle of Otsu method and its application in image segmentation, and according to the distribution characteristics of the target and background, an improved threshold image segmentation algorithm based on the Otsu method is developed. By narrowing the selection range of threshold and searching the minimum variance ratio, the improved algorithm selects the optimal threshold. Through the compared with the Otsu method and other methods, the results show that the new improved algorithm has these advantages such as high segmentation precision and fast computation speed.
Prolastin, a pharmaceutical preparation of purified human α1-antitrypsin, blocks endotoxin-mediated cytokine release (2005)

Our data demonstrate for the first time that Prolastin inhibits bacterial endotoxin-induced pro-inflammatory responses in vitro and in vivo, and provide scientific bases to explore new Prolastin-based therapies for individuals with inherited AAT deficiency, but also for other clinical conditions.
Maternal Stress Combined with Terbutaline Leads to Comorbid Autistic-Like Behavior and Epilepsy in a Rat Model (2015)

Human autism is comorbid with epilepsy, yet, little is known about the causes or risk factors leading to this combined neurological syndrome. Although genetic predisposition can play a substantial role, our objective was to investigate whether maternal environmental factors alone could be sufficient. We examined the independent and combined effects of maternal stress and terbutaline (used to arrest preterm labor), autism risk factors in humans, on measures of both autistic-like behavior and epilepsy in Sprague-Dawley rats. Pregnant dams were exposed to mild stress (foot shocks at 1 week intervals) throughout pregnancy. Pups were injected with terbutaline on postnatal days 2-5. Either maternal stress or terbutaline resulted in autistic-like behaviors in offspring (stereotyped/repetitive behaviors and deficits in social interaction or communication), but neither resulted in epilepsy. However, their combination resulted in severe behavioral symptoms, as well as spontaneous recurrent convulsive seizures in 45% and epileptiform spikes in 100%, of the rats. Hippocampal gliosis (GFAP reactivity) was correlated with both abnormal behavior and spontaneous seizures. We conclude that prenatal insults alone can cause comorbid autism and epilepsy but it requires a combination of teratogens to achieve this; testing single teratogens independently and not examining combinatorial effects may fail to reveal key risk factors in humans. Moreover, astrogliosis may be common to both teratogens. This new animal model of combined autism and epilepsy permits the experimental investigation of both the cellular mechanisms and potential intervention strategies for this debilitating comorbid syndrome.
A treatise on the mathematical theory (1944)

Mots-clefs: Elasticite ; Statique Reference Notice creee le 2004-09-07, modifiee le 2016-08-08
Expression of the Interleukin‐10 Signaling Pathway Genes in Individuals With Down Syndrome and Periodontitis (2011)

Reduced expression of IL-10 coupled with a possible increase of STAT3 activation (increase of STAT3 and reduction of SOCS3 mRNA) indicates an important modulation of the immune response, with attenuation of anti-inflammatory and increase of proinflammatory mediators. This modulation may be related to the increased prevalence and severity of periodontitis in individuals with DS.
Conformationally restricted thiazole derivatives as novel class of 5-HT3 receptor ligands (1995)

A new series of tricyclic derivatives of 2-methyl-naphtho[1,2-d]thiazole were synthesized in order to investigate the effects of the conformational restriction of bicyclic thiazole derivatives previously reported on the 5-HT 3 receptor affinity. The basic moiety in these compounds is represented by the terminal nitrogen of N-methyl-piperazine or N-methyl-piperidine ring linked at 2-methyl. All the tricyclic derivatives have a significant 5-HT 3 receptor binding affinity and the terminal piperazine ring is more suitable than piperidine one
<b>Aaron E. Wright</b>, ‘Hie lert uns der meister’. Latin Commentary and the German Fable 1350–1500. 2001 (2002)

Since the appearance of his Princeton dissertation in 1991 (on the Nürnberger Prosa-Äsop ), Aaron E. Wright has established himself, thanks to a string of articles and a critical edition of the fable collection of the Anonymus Neveleti, as a major authority in the field of fable studies. This new monograph, which is innovative, thoroughly documented and outstandingly well written, can only enhance his reputation.
Sound Source Separation: Azimuth Discrimination and Resynthesis (2004)

In this paper we present a novel sound source separation algorithm which requires no prior knowledge, no learning, assisted or otherwise, and performs the task of separation based purely on azimuth discrimination within the stereo field. The algorithm exploits the use of the “pan pot ” as a means to achieve image localisation within stereophonic recordings. As such, only an interaural intensity difference exists between left and right channels for a single source. We use gain scaling and phase cancellation techniques to expose frequency dependent nulls across the azimuth do-main, from which source separation and resynthesis is carried out. We present results obtained from real re-cordings, and show that for musical recordings, the algo-rithm improves upon the output quality of current source separation schemes. 1.
The largest subunit of RNA polymerase II (rpb1) as a phylogenetic marker of seed plant species (2004)

The phylogeny of land plants, especially angiosperms, has been perplexing scientists for more than 125 years. The aim of this study was to help elucidate unanswered phylogenetic issues using rpb1 genes from twenty-six land plant species (8 gymnosperm species, 17 angiosperm species and Psilotum, a fernally, as the outgroup). The sixteen rpb1 genes which were sequenced in this study had very similar lengths and contained no base compositional bias. Synonymous substitutions of rpb1 sequences were saturated when compared to the outgroup. The third codon positions of these genes contained misleading phylogenetic information. The topology of trees based on first and second codon positions were in line with that of protein trees. Both angiosperms and gymnosperms were monophyletic. Amborella was found at the base of the angiosperm tree, followed by Nymphae, then Illicium. These data rejected the anthophyte hypothesis, weakly supported the gnepine hypothesis, but did not resolve the interrelationship among eumagnoliids and eudicots. rpb1 genes were combined with the 18S ribosomal RNA gene and chloroplast atpB and rbcL genes to obtain more robust phylogenies. This combined data set produced a topology similar to that of the first and second positions of rpb1 genes except that they better resolved the interrelationship among eumagnoliids and eudicots. We conclude that our rpb1 sequences evolve too slowly to provide enough phylogenetic information to fully resolve the phylogeny of seed plants and that other gene sequences will need to be added to these data sets to obtain a well-resolved phylogenetic tree of seed plants.
A representation method of color pictures by arranging fixed size dots of the primary colors (2005)

Recently there has been an increasing demand for high quality color pictures that can be printed using color dot printers such as ink jet or thermal transfer printers. In this paper, we consider the criteria for the good representation of color pictures and the essential points of the representation processing to satisfy these criteria. We describe a new method for the representation of color pictures based on arranging fixed size primary color dots. This method makes it possible to reproduce the original image colors without losing their smoothness or fineness.
A consistent pixel-wise blur measure for partially blurred images (2014)

Despite numerous efforts on blur measurement of partially blurred images, there still lacks an effective blur measure that is both pixel-wise and locally sharp consistent. The paper proposes a novel method with two contributions to overcome this limitation: 1) A new pixel-based blur metric, Multi-resolution Singular Value (MSV), which leverages the average singular value of high frequency bands to measure the blur of each pixel, and 2) a locally continuous strategy, maximum-likelihood estimation (MLE) based refinement, that ensures local continuity by imposing the local sharp consistency on pixel blur in a local correcting process. Experimental results show that our method is effective to smoothly measure the partially blurred images without local discontinuity.