gebhart/patrepeval huggingface dataset:
Effectiveness of Continuously Infused Dtpa Therapy in Reducing the Radiation Dose From Inhaled 244Cm2O3 Aerosols (1992)

Radionuclide decorporation is the only effective method of reducing radiation dose for persons contaminated accidentally. In this study, dogs that had inhaled a moderately soluble aerosol of 244Cm2O3 were treated with either discrete intravenous injections of the chelating agent diethylenetriaminepentaacetic acid (Zn-DTPA) or with subcutaneous infusion of Zn-DTPA at either 30 or 120 mumol kg-1 d-1. Each treatment regimen was continued for 64 d, whereupon all animals were killed, and collected excreta and tissue samples were analyzed for curium. All DTPA treatment methods were effective. A total of 89% of the initial pulmonary burden (IPB) was removed by DTPA injection, whereas 94% IPB was removed by the low dose of infused DTPA and 97% by the high dose treatment. Thus, low and high infused doses of DTPA prevented the translocation of greater than 99.5% of curium to liver and 97-99% to bone and kidney. The resultant dose reductions to these organs were superior to those achieved by intravenous DTPA injections.
The rat sperm proteome characterized <b><i>via</i></b> IPG strip prefractionation and LC‐MS/MS identification (2008)

Abstract Proteomics represents a powerful tool for the analysis of mammalian spermatozoa, since these terminally differentiated cells are transcriptionally inactive and exhibit a limited dynamic range of protein expression. Here we report the identification of 5123 peptides, leading to 829 unambiguous and 2215 redundant gene products found to be present within rat spermatozoa derived from the cauda epididymis. Bioinformatics demonstrated that 60 proteins appeared to be specifically expressed in the genitourinary tract, including pyruvate dehydrogenase 1, ropporin, testis‐specific serine kinase 4, testis‐specific transporter, and retinol dehydrogenase 14. We also identified eight members of the ADAM family, seven of which have previously been detected in spermatozoa (ADAM2, ‐3, ‐4, ‐5, ‐6, ‐7, and ‐30) while ADAM34 has been identified in the sperm proteome for the first time. Approximately 21 gene products were found to possess isomerase activity including peptidylprolyl cis / trans isomerases that are known to be involved in germ cell differentiation and protein disulfide isomerases that have been implicated in sperm–oocyte fusion. Furthermore, 51 gene products clustered into ion‐transporter activity. This inventory of gene products, the first ever 2‐D LC‐MS/MS analysis of rat spermatozoa, will be invaluable in directing future research into the molecular mechanisms that drive these highly specialized cells.
Genome-Wide Analysis of STAT Target Genes (2004)

Inappropriate activation of transcription factors is a common event in cancer. These transcription factors contribute to a malignant phenotype by regulating genes involved in cellular proliferation, survival, differentiation, angiogenesis, and invasion. An important goal remains identifying the targets of oncogenic transcription factors that execute these changes. STAT proteins are among the best-studied of these transcription factors, and are involved in oncogenesis both in vivo and in vitro. They thus represent an ideal model for understanding how transcription factors cause cancer through coordinated changes in gene expression. Recent studies have employed microarray-based expression analysis to comprehensively identify STAT target genes. Analysis of these targets can provide insight into mechanisms of neoplastic transformation, and may shed light on new strategies for targeted therapy.
The Effect of Low Glucose Degradation Product Dialysis Solution on Epithelial-To-Mesenchymal Transition in Continuous Ambulatory Peritoneal Dialysis Patients (2005)

Low-GDP solution showed beneficial effects such as rapid remesothelialization and less EMT in the peritoneum with time on PD.
Near-infrared semiconductor subwavelength-wire lasers (2006)

We report near-infrared lasing in the telecommunications band in gallium antimonide semiconductor subwavelength wires. Our results open the possibility of the use of semiconductor subwavelength-wire lasers in future photonic integrated circuits for telecommunications applications.
Information-Theoretic Timed-Release Security: Key-Agreement, Encryption, and Authentication Codes. (2012)

In this paper, we study timed-release cryptography with information-theoretic security. As fundamental cryptographic primitives with information-theoretic security, we can consider key-agreement, encryption, and authentication codes. Therefore, in this paper we deal with information-theoretic timed-release security for all those primitives. Specically, we propose models and formal-izations of security for information-theoretic timed-release key-agreement, encryption, and authenti-cation codes; we also derive tight lower bounds on entities &apos; memory-sizes required for all those ones; and we show optimal constructions of all those ones. Furthermore, we investigate a relationship of mechanisms between information-theoretic timed-release key-agreement and information-theoretic key-insulated key-agreement. It turns out that there exists a simple algorithm which converts the former into the latter, and vice versa. In the sense, we conclude that these two mechanisms are essentially close. 1
Formant-based feature extraction for emotion classification from speech (2015)

In a previous study, a robust formant-tracking algorithm was introduced to model formant and spectral properties of speech. The algorithm utilizes Gaussian mixtures to estimate spectral parameters, and refines the estimates by using a maximum a posteriori adaptation (MAP) algorithm. In this paper, the formant-tracking algorithm was used to extract the formant-based features for emotion classification. The classification results were compared to a linear predictive coding (LPC) based algorithm for evaluation. On average, the formant features extracted using the algorithm improved the unweighted accuracy by 2.1 percentage points when compared to a LPC-based algorithm. The combination of formant features and other acoustic features statistically significantly improved the unweighted accuracy by 2.7 percentage points, whereas the LPC-based features barely improved it by 1 percentage point. The results clearly indicate that an improved formant-tracking method improved emotion classification accuracy. The effect of formant-based features in emotion classification is also discussed.
Evaluation of Supercritical Fluid Extraction in the Pharmaceutical Industry (1986)

Various steroids precipitate from supercritical CO(2) as very small particles but still retain their crystallinity. This suggests that SCFE in this industry could be utilized as a size reduction method as an alternative to milling. The application of SCFE as a separation technique is demonstrated by the simultaneous extraction and reaction of mevinolin, a metabolite of the fungus Aspergillus terreus.
Cysteamine Enhances in Vitro Development of Porcine Oocytes Matured and Fertilized in Vitro (1995)

Most porcine oocytes matured and fertilized in vitro fail to develop normally due to abnormal fertilization. The aim of this study was to determine the effect of cysteamine on pronuclear formation and developmental competence in pig embryos produced in vitro. Follicular oocytes were matured in vitro with or without cysteamine in Medium 199 supplemented with sodium pyruvate, FSH, LH, 17 beta-estradiol, antibiotics, and 25% porcine follicular fluid. Matured oocytes were then inseminated for 10 h. In the first experiment, pronuclear formation was assessed immediately after the insemination period. The addition of 50 microM or 500 microM cysteamine to the maturation medium increased male pronuclear development, resulting in a higher proportion of oocytes with synchronously formed male and female pronuclei. The frequency of synchronous pronuclear formation was increased in monospermic oocytes from 10% in the control group to 43% (p < 0.001) and 45% (p < 0.001), respectively, and in polyspermic oocytes from 43% in the control group to 68% (p < 0.05) and 75% (p < 0.001), respectively. In the second experiment, development of the in-vitro produced embryos was assessed after 7 days of culture in vitro. The addition 500 microM cysteamine to the maturation medium increased the percentage of cleaving embryos developing to the 8-cell (37% vs. 16%; p < 0.001), morula (19% vs. 6%; p < 0.001), and blastocyst (12% vs. 1%; p < 0.001) stages. These results demonstrate that the addition of cysteamine to maturation medium increases synchronous pronuclear formation and normal embryonic development in porcine oocytes matured and fertilized in vitro.
Pantoea punctata sp. nov., Pantoea citrea sp. nov., and Pantoea terrea sp. nov. Isolated from Fruit and Soil Samples (1992)

A total of 37 bacterial strains with the general characteristics of the family Enterobacteriaceae were isolated from fruit and soil samples in Japan as producers of 2,5-diketo-D-gluconic acid from D-glucose. These organisms were phenotypically most closely related to the genus Pantoea (F. Gavini, J. Mergaert, A. Beji, C. Mielearek, D. Izard, K. Kersters, and J. De Ley, Int. J. Syst. Bacteriol. 39:337-345, 1989) and were divided into three phenotypic groups. We selected nine representative strains from the three groups for an examination of DNA relatedness, as determined by the S1 nuclease method at 60 degrees C. Strain SHS 2003T (T = type strain) exhibited 30 to 41 and 28 to 33% DNA relatedness to the strains belonging to the strain SHS 2006T group (strains SHS 2004, SHS 2005, SHS 2006T, and SHS 2007) and to the strains belonging to the strain SHS 2008T group (strains SHS 2008T, SHS 2009, SHS 2010, and SHS 2011), respectively. Strain SHS 2006T exhibited 38 to 46% DNA relatedness to the strains belonging to the strain SHS 2008T group. The levels of DNA relatedness within the strain SHS 2006T group and within the strain SHS 2008T group were more than 85 and 71%, respectively. Strain SHS 2003T, SHS 2006T, and SHS 2008T DNAs exhibited less than 18% binding to Pantoea dispersa ATCC 14589T and Pantoea agglomerans ATCC 27155T DNAs.(ABSTRACT TRUNCATED AT 250 WORDS)
Rapid Quantitation of Furanocoumarins and Flavonoids in Grapefruit Juice using Ultra‐Performance Liquid Chromatography (2013)

These analytical methods provide an expedient means to quantitate key furanocoumarins and flavonoids in grapefruit juice and other foods used in dietary substance-drug interaction studies.
Forskolin Carbamates: Binding and Activation Studies with Type I Adenylyl Cyclase (1996)

Three series of analogs were regioselectively prepared from a protected forskolin precursor to afford 7-carbamoyl-7-desacetylforskolins (series 1), 6-carbamoyl-7-desacetylforskolins (series 2), and 6-carbamoylforskolins (series 3). The analogs were pharmacologically evaluated for binding (IC50) to and activation (EC50) of type I adenylyl cyclase in membranes from stably transfected Sf9 cell lines expressing a single adenylate cyclase subtype. The following ranges were determined for the IC50's and EC50's of each individual series: series 1, IC50 = 43-1600 nM, EC50 = 0.5-9.6 microM; series 2, IC50 = 65-680 nM, EC50 = 0.63-6.5 microM; series 3, IC50 = 21-271 nM, EC50 = 0.5-8.1 microM (forskolin IC50 = 41 nM and EC50 = 0.5 microM). Activation paralleled binding; however, some analogs exhibited poor binding and good activation whereas others demonstrated good binding but poor activation. Steric bulk tended to diminish binding and activation when at the 6- or 7-position, although bulk was accommodated at the 6-position if the 7-site was reacetylated. Acylation of the 7-position by the carbamoyl linker or acetyl was important for obtaining good binding and activation; however, the effect was more pronounced with binding. For both binding and activation, small, linear, lipophilic substituents (propyl, allyl, isopropyl) are well tolerated at the 7-position but less so in the 6-position, even when the 7-site is reacetylated. Planar aromatic moieties (phenyl and 2-pyridinyl) demonstrated moderate to good potency for binding and activation when located at either the 6- or 7-positions. There is an overall trend toward increasing potency for both binding and activation with polar substituents.
Anisotropic Wet Etching of Aluminum Electrodes by an Evacuated Etching System (1985)

Wet etching of Al/Si (2%) films for fine pattern engraving has been studied using an evacuated wet etching system. The results indicate that isotropic etching by conventional atmospheric wet etching changes to quasi‐anisotropic etching with decreasing pressure. The amount of lateral etching beneath the photoresist pattern, which is around 0.8 μm in conventional atmospheric wet etching, decreases with decreasing pressure and reaches 0.42 μm at a pressure of 9 torr. Uniformity of lateral etching is much better than that by conventional wet and dry etching. This technique is useful in the manufacture of fine‐pattern aluminum electrodes, for instance, with 1.0–1.2 μm linewidths.
AlphaClean: Automatic Generation of Data Cleaning Pipelines (2019)

The analyst effort in data cleaning is gradually shifting away from the design of hand-written scripts to building and tuning complex pipelines of automated data cleaning libraries. Hyper-parameter tuning for data cleaning is very different than hyper-parameter tuning for machine learning since the pipeline components and objective functions have structure that tuning algorithms can exploit. This paper proposes a framework, called AlphaClean, that rethinks parameter tuning for data cleaning pipelines. AlphaClean provides users with a rich library to define data quality measures with weighted sums of SQL aggregate queries. AlphaClean applies generate-then-search framework where each pipelined cleaning operator contributes candidate transformations to a shared pool. Asynchronously, in separate threads, a search algorithm sequences them into cleaning pipelines that maximize the user-defined quality measures. This architecture allows AlphaClean to apply a number of optimizations including incremental evaluation of the quality measures and learning dynamic pruning rules to reduce the search space. Our experiments on real and synthetic benchmarks suggest that AlphaClean finds solutions of up-to 9x higher quality than naively applying state-of-the-art parameter tuning methods, is significantly more robust to straggling data cleaning methods and redundancy in the data cleaning library, and can incorporate state-of-the-art cleaning systems such as HoloClean as cleaning operators.
Temperature Effect on Yield and Yield Components of Different Rice Cultivars in Flowering Stage (2014)

In order to study the effect of cold stress in flowering stage on yield and yield components of different rice cultivars, an experiment was performed as split plot factorial based on completely randomized design (CRD) in greenhouse of deputy of rice research institute of Iran (Amol) in 2010, in three repetitions. Treatment included 5 varieties as main factors that included cultivars of shirudi, fajr, local tarom, hybrid, and line 843. Two levels of temperatures <a:math xmlns:a="http://www.w3.org/1998/Math/MathML" id="M1"> <a:mrow> <a:msub> <a:mrow> <a:mi>T</a:mi> </a:mrow> <a:mrow> <a:mn fontstyle="italic">1</a:mn> </a:mrow> </a:msub> </a:mrow> </a:math> (13°C, stress temperature) and <d:math xmlns:d="http://www.w3.org/1998/Math/MathML" id="M2"> <d:mrow> <d:msub> <d:mrow> <d:mi>T</d:mi> </d:mrow> <d:mrow> <d:mn fontstyle="italic">2</d:mn> </d:mrow> </d:msub> </d:mrow> </d:math> (32°C, normal temperature, control) along with flowering stage were selected as two subfactors. Three seedlings were planted in each plot. The cold stress was done in flowering stage with holding pots at 13°C for 15 days. Results showed that low temperature had significant effect in level of 1 percent on all characters, such as the number of panicles, the length of panicle, and the number of full, empty, and total grains; as a result, yield had caused significant reduction. Interaction between temperature and varieties showed that most tolerant variety in relation to temperature stress along with least percentage yield (19%) is shirudi variety and the most sensitive one with most percentage of yield decrease (29%) was local tarom variety.
Enhanced UV photosensitivity in fibers and waveguides by high-pressure hydrogen loading (1995)

In early work on photosensitivity in optical fibers, the optically induced refractive index changes depended on glass composition and processing-related Ge defects.1 Later work showed that high-temperature treatments could be used to increase Ge defect levels and to enhance the UV sensitivity.2 More recently, it was discovered that GeO2-doped fibers and wave-guides show extremely high UV photosensitivity when they are first sensitized by loading the glass with several mole percent of H2 molecules.3 H2 (or D2) molecules are diffused inertly into an optical fiber at high pressure. Subsequent UV irradiation (e.g., 242-248 nm) causes the dissolved H2 to react in the doped silica, altering the glass network and leading to large refractive index changes.
A new version of the Fast Multipole Method for the Laplace equation in three dimensions (1997)

We introduce a new version of the Fast Multipole Method for the evaluation of potential fields in three dimensions. It is based on a new diagonal form for translation operators and yields high accuracy at a reasonable cost.
Calculating standard drink units: international comparisons (1991)

Simple calculation rules are providing for converting alcohol consumption data among four standard units currently used by researchers and educators in the USA, Canada, the UK, and Australia. A plea is made for the adoption of a common method for reporting alcohol consumption in research, using metric fluid volume units.
Documento de avaliacao ambiental e plano de gestao ambiental (2005)

The Integrated Management of Aquatic Resources (AquaBio) Project in the Amazon region, aims at testing the development, and implementation of an innovative approach to the conservation, and sustainable use of aquatic ecosystems in three sub-basins that, together with the Floodplain Natural Resources Management Project (ProVarzea), would provide a representative sample of Amazonian aquatic ecosystems, and the problems that affect them. To this end, and in support of the project, this environmental assessment (EA) provides the tools to evaluate those positive environmental impacts, as well as mitigate any potential environmental adversity. Subprojects will be subject to an environmental screening that will determine their acceptability, based on an environmental questionnaire determining their level of positive (not significant, moderate, or significant), or negative impacts. Accordingly, an environmental analysis will guide the management process for each subproject, to include the appropriate (aquatic and water resources) biodiversity conservation and mitigation measures. This EA stipulates no subproject will be located within protected areas (national parks, reserves, etc.),and, should a subproject be located in the proximity of protected areas, proposed activities shall be limited to agricultural conservation, forestry development (with native species, or proven genetic mutations), ecotourism, and/or other sustainable agro-forestry activities. Mitigation measures specify: regular monitoring of water quality (with particular attention to floatable solids), as well as the depth in every water body; based on a wildlife census, biological monitoring shall ensure natural habitats are adequate to aquatic and wildlife; regular testing of organic material, and control of chemical and industrial residues; fisheries will be regulated, accompanied by inspections on commercial fishing (including aquaculture); vegetation will be kept regularly clean, and fire controls and preventive actions will be conducted.
ChemInform Abstract: Highly Z Selective Synthesis of Functionalized Monoterpenoids via N‐ Ylide (2,3)Sigmatropic Rearrangement and Its Application to 13‐cis‐ Retinol. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Restructuring the System Is the Solution. (1988)

E UDUCATIONAL systems of the 21st century will be drastically different from those of today. Whether Americans lead the world in this educational trans formation or play catch-up with more en terprising cultures will do much to de termine whether the U.S. will continue to play an international leadership role in the ever more competitive world of the 21st century. Powerful forces are reshaping nation al and global economies. For the U.S. to thrive in the face of intensifying inter national competition, accelerating tech nological change, oppressive public and private debt, and changes in the popula tion and in the work force, the learning enterprise must become far more produc tive. When an economy is knowledge based, learning becomes a strategically critical industry. The U.S. educational system is at a crossroads. A business-as-usual approach to education policy and even to reform -will lead to an increasingly troubled future for both education and the econo my. Alternatively, a commitment now to restructu ing the basic technology and or ganization o education offers a far more rewarding scenario for both the schools and the country.
An effective wrapper architecture to heterogeneous data source (2003)

In this paper, we focus on the problem in information integration systems of obtaining data from an heterogeneous data source accurately and effectively. XML is used as data exchange format of the wrapper. We design the wrapper architecture based on the conversion and management of the views as the bridge from global schema to local schema of various data sources. Our wrapper has two main subsystems, the data extract subsystem and query executor subsystem. The former is for loading data for the cache in the mediator when changes more than threshold are detected, and the latter is for answering the query from the mediator. The architecture adapts to the data and schema change of the data source and could answer the query of the mediator effectively. Considering the wrapper may run in the environment without control, the process in the wrapper should be simple enough. The storage in the wrapper itself should be as small as possible and the storage of data source could be used. The detail of the module query rewrite, view management, query merge, result wrap and schema change detect are discussed. The behavior of the wrapper during the query process in the wrapper is discussed with a running example. The security strategy, especially in the distance that the wrapper runs in autonomic data source, is also introduced in this paper.