gebhart/patrepeval huggingface dataset:
Oral Citicoline in Acute Ischemic Stroke (2002)

Treatment with oral citicoline within the first 24 hours after onset in patients with moderate to severe stroke increases the probability of complete recovery at 3 months.
A Five-Order Mode Converter for Multimode Waveguide (2004)

A numerical model of five-order mode converter that converts the order of modes in an integrated-optic multimode waveguide is proposed. Such a structure is useful in optical guiding wave devices for mode control and mode shuffling. The dimensions and index profile of the device are well within the capabilities of the state of the art of integrated optics technology. We have successfully optimized the structural design of the device for propagation loss of less than 13.1 dB at an operating wavelength of 1.55 μm. A cascaded form of the five-order mode converter is also proposed for selective mode conversion without the need of restructuring the connection within the device.
Interview with Vincent du Vigneaud (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInterview with Vincent du VigneaudRobert A. Plane Cite this: J. Chem. Educ. 1976, 53, 1, 8Publication Date (Print):January 1, 1976Publication History Received3 August 2009Published online1 January 1976Published inissue 1 January 1976https://doi.org/10.1021/ed053p8RIGHTS & PERMISSIONSArticle Views56Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (4 MB) Get e-Alertsclose Get e-Alerts
Increasing efficiency of information transmission with interference influence by the use of multi-parameter adaptation (2013)

We propose a method for increasing the efficiency of wireless data transmission system by means of a multi-parameter adaptation. Multi-criteria optimization is carried out to select a set of parameters that are Pareto-optimal solutions. A patented structure and algorithm of adaptive transceiver proposed. Simulation model of the system synthesized and the results of an experimental study based on it presents.
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway (2020)

EphA5 knockdown promotes the proliferation of esophageal squamous cell carcinoma,enhances invasion and migration ability via epithelial-mesenchymal transition through activating Wnt/β‑catenin pathway.
Autoencoders for music sound modeling: a comparison of linear, shallow, deep, recurrent and variational models (2018)

This study investigates the use of non-linear unsupervised dimensionality reduction techniques to compress a music dataset into a low-dimensional representation which can be used in turn for the synthesis of new sounds. We systematically compare (shallow) autoencoders (AEs), deep autoencoders (DAEs), recurrent autoencoders (with Long Short-Term Memory cells -- LSTM-AEs) and variational autoencoders (VAEs) with principal component analysis (PCA) for representing the high-resolution short-term magnitude spectrum of a large and dense dataset of music notes into a lower-dimensional vector (and then convert it back to a magnitude spectrum used for sound resynthesis). Our experiments were conducted on the publicly available multi-instrument and multi-pitch database NSynth. Interestingly and contrary to the recent literature on image processing, we can show that PCA systematically outperforms shallow AE. Only deep and recurrent architectures (DAEs and LSTM-AEs) lead to a lower reconstruction error. The optimization criterion in VAEs being the sum of the reconstruction error and a regularization term, it naturally leads to a lower reconstruction accuracy than DAEs but we show that VAEs are still able to outperform PCA while providing a low-dimensional latent space with nice "usability" properties. We also provide corresponding objective measures of perceptual audio quality (PEMO-Q scores), which generally correlate well with the reconstruction error.
Ovarian cancer in Europe: Cross-sectional trends in incidence and mortality in 28 countries, 1953-2000 (2004)

We have considered trends in incidence and mortality in 28 European countries using incidence data from successive volumes of Cancer Incidence in Five Continents and mortality from the WHO database. Countries with the highest rates in the early 1960s included the Nordic countries, Austria, Germany and the United Kingdom, but trends in these areas have tended to decline over recent calendar periods, particularly with regard to mortality. Southern European countries showed upward trends, at least until the early 1980s for France and Italy. Likewise, in most central and eastern European countries, ovarian cancer incidence and mortality rates were originally relatively low, but tended to rise over time. Falls in mortality, but not in incidence, over recent years were observed in the Czech Republic and Hungary. In several countries, mainly in northern Europe, trends were more favorable at younger age (25-49 years) than in the subsequent age groups. Thus, recent trends in ovarian cancer have led to a leveling of rates across various areas of the continent, although a 2.5-fold variation was still observed in the late 1990s between the highest mortality rate of 9.3/100,000 in Denmark and the lowest one of 3.6 in Portugal. These patterns should be viewed in the light of an observed reduction in parity, mainly in southern and eastern Europe, and the spread of oral contraceptive use, mainly in northern Europe, since these are the best recognized protective factors with regard to ovarian carcinogenesis. The declining mortality trends can also in part be ascribed to improvements in treatment.
Early diagnosis of resistant pathogens (2013)

Infections with organisms that are resistant to various anti-microbial agents pose a serious challenge to effective management of infections. Resistance to antimicrobial agents, which may be intrinsic or acquired, has been noted in a wide variety of microorganisms causing human infections. These include resistance to antiviral agents in HIV, HBV, CMV and influenza virus, anti-parasitic agents in Plasmodium falciparum, anti-fungal agents in certain Candida species and MDR (multidrug-resistant) tuberculosis. It is however, the problem of multidrug-resistant bacterial infections (caused by MRSA, VRE, ESBL/AmpC/metallo-β lactamase producers and colistin-resistant Gram-negative bacilli) that has become a cause of major concern in clinical settings. Infections with these organisms can increase morbidity, mortality, increase the cost of therapy and increase the duration of hospitalization. The objective of this article is to review the question how early diagnosis of these infections, affects the overall management of infected or colonized patients, with regard to antimicrobial therapy.
Fourier transform Raman spectroscopy of biological materials (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFourier transform Raman spectroscopy of biological materialsIra W. Levin and E. Neil LewisCite this: Anal. Chem. 1990, 62, 21, 1101A–1111APublication Date (Print):November 1, 1990Publication History Published online22 September 2008Published inissue 1 November 1990https://pubs.acs.org/doi/10.1021/ac00220a001https://doi.org/10.1021/ac00220a001research-articleACS PublicationsRequest reuse permissionsArticle Views370Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The reduced-interference local Wigner-Ville distribution (2002)

The local Wigner-Ville distribution (LWVD) extends the Cohen's class time-frequency distributions (TFD) by the definition of a kernel for each time-frequency point (local kernel). The subject of the paper is the determination of these local kernels for interference reduction. Starting from the simple idea of the local limitation of the Wigner-Ville TFD integral bounds, a method is presented to estimate these limits and to obtain a reduced interference TFD. The effectiveness for interference reduction of this LWVD, especially when compared to global-kernel methods, is shown using example signals.
MESSAGE COMPLEXITY OF THE TREE QUORUM ALGORITHM FOR DISTRIBUTED MUTUAL EXCLUSION (1994)

The tree quorum algorithm (TQA), which logically organizes the sites in a system into a tree, is an efficient and fault-tolerant solution for distributed mutual exclusion. Quorum size can be reduced to log N in the best case of TQA. In this paper, message complexity of TQA is analyzed. Moreover, it is shown that the ratio of message complexity to quorum size converges to 1/p, where p is the probability that a site is operational. >
Surgery followed by Persistence of High-Grade Squamous Intraepithelial Lesions Is Associated with the Induction of a Dysfunctional HPV16-Specific T-Cell Response (2008)

The presence of HPV16-specific T cells with a non-Th1/Th2 cytokine and even suppressive signature in patients with HSIL may affect the outcome of vaccine approaches aiming at reinforcing human papillomavirus-specific immunity to attack human papillomavirus-induced lesions.
Room-temperature diode lasers operating at 2.78 μm for enhanced CO 2 detection (1995)

We describe room-temperature 2.78-micrometers AlGaAsSb/InGaAsSb multi-quantum well lasers. Pulsed laser operation was observed with threshold currents of 1.1 A, a maximum power output of 95 mW, and a maximum differential quantum efficiency of 9%. Lasers operated pulsed up to 60 degree(s)C with a characteristic temperature of 58 K over the range of 0 - 40 degree(s)C. Continuous wave operation was observed up to 200 K, with a peak emission wavelength of 2.665 micrometers . To date, 2.78 micrometers is the longest emission wavelength for a room-temperature III-V laser.
Effect of water activity and pH on growth and toxin production by Clostridium botulinum type G (1986)

The combined effect of water activity (aw) and pH on growth and toxin production by Clostridium botulinum type G strain 89 was investigated. The minimum aw at which growth and toxin formation occurred was 0.965, for media in which the pH was adjusted with either sodium chloride or sucrose. The minimum pH (at the optimum aw) for growth and toxin production of C. botulinum type G was found to be 5.6. Optimum conditions for toxin activation were a trypsin concentration of 0.1%, a pH of the medium of 6.5, and an incubation for 45 min at 37 degrees C. These data did not show evidence of heat-labile spores, since a heat shock of 75 degrees C for 10 min did not significantly decrease the spore count of strain 89G in media at pH 7.0 or 5.6. It was frequently observed that cells grown at reduced aw or pH experienced severe morphological changes.
A simple and rapid method of direct sequencing using Dynabeads (1991)

Highly specific regions of genomic DNA can now be produced in large quantities by enzymatic amplification using the polymerase chain reaction (PCR) and a thermostable Taq polymerase (Saiki et al. 1988). This has encouraged the development of direct sequencing of the amplified DNA. Apart from the obvious advantage of the avoidance of cloning of DNA, direct sequencing enables both alleles to be analysed simultaneously. The latter is particularly advantageous in heterozygous states where the mutant allele cannot be differentiated from the normal. However, direct dideoxy sequencing of PCR‐amplified DNA is still not consistently satisfactory. The difficulty arises from the nature of the PCR‐amplified DNA which consists of short, linear double‐stranded DNA. The two strands of the DNA can rapidly reanneal during DNA sequencing, blocking or displacing the sequencing primer from the template strand, thereby decreasing the amount of specific termination products formed in the sequencing reactions.
Automatic frequency correction scheme forspread spectrum coherent RAKE receiver (1998)

An automatic frequency correction scheme for a spread spectrum communication system with a pilot channel is proposed. The results of computer simulation show that this scheme improves the performance of the mobile receiver.
Extração de DNA por meio de uma abordagem experimental investigativa (2010)

A ausência de contextualização de conteúdos, remetendo os alunos a uma abordagem estritamente teórica, dificulta o processo de ensino-aprendizagem (KRASILCHIK, 2004). Por isso, o trabalho com temas relacionados à Genética em sala de aula possibilita experiências em que os alunos podem contextualizar o assunto associando-o às situações cotidianas. Além da associação, é possível trabalhar outros aprendizados de forma transversal, como preconizado pelos PCNEM (Parâmetros Curriculares Nacionais do Ensino Médio), considerando a importância da construção do conhecimento sob uma perspectiva teórico-prática (BRASIL, 2000). [...]
ChemInform Abstract: Computer‐Assisted Series Design in Chemical Synthesis of Bioactive Compounds (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
<scp>betawrap</scp> : Successful prediction of parallel β-helices from primary sequence reveals an association with many microbial pathogens (2001)

The amino acid sequence rules that specify beta-sheet structure in proteins remain obscure. A subclass of beta-sheet proteins, parallel beta-helices, represent a processive folding of the chain into an elongated topologically simpler fold than globular beta-sheets. In this paper, we present a computational approach that predicts the right-handed parallel beta-helix supersecondary structural motif in primary amino acid sequences by using beta-strand interactions learned from non-beta-helix structures. A program called BETAWRAP (http://theory.lcs.mit.edu/betawrap) implements this method and recognizes each of the seven known parallel beta-helix families, when trained on the known parallel beta-helices from outside that family. BETAWRAP identifies 2,448 sequences among 595,890 screened from the National Center for Biotechnology Information (NCBI; http://www.ncbi.nlm.nih.gov/) nonredundant protein database as likely parallel beta-helices. It identifies surprisingly many bacterial and fungal protein sequences that play a role in human infectious disease; these include toxins, virulence factors, adhesins, and surface proteins of Chlamydia, Helicobacteria, Bordetella, Leishmania, Borrelia, Rickettsia, Neisseria, and Bacillus anthracis. Also unexpected was the rarity of the parallel beta-helix fold and its predicted sequences among higher eukaryotes. The computational method introduced here can be called a three-dimensional dynamic profile method because it generates interstrand pairwise correlations from a processive sequence wrap. Such methods may be applicable to recognizing other beta structures for which strand topology and profiles of residue accessibility are well conserved.
Configuring BlueStars: multihop scatternet formation for Bluetooth networks (2003)

Describes a protocol for the establishment of multihop ad hoc networks based on Bluetooth devices. The protocol proceeds in three phases: device discovery, partitioning of the network into Bluetooth piconets, and interconnection of the piconets into a connected scatternet. The protocol has the following desirable properties: it is executed at each node with no prior knowledge of the network topology, thus being fully distributed. The selection of the Bluetooth masters is driven by the suitability of a node to be the "best fit" for serving as a master. The generated scatternet is a connected mesh with multiple paths between any pair of nodes, thus achieving robustness. Differently from existing solutions, no extra hardware is required to run the protocol at each node and there is no need for a designated node to start the scatternet formation process. Simulation results are provided which evaluate the impact of the Bluetooth device discovery phase on the performance of the protocol.
Compact Switched-Beam Antenna Employing a Four-Element Slot Antenna Array for Digital Home Applications (2008)

In this paper a compact switched-beam antenna is proposed. The antenna is composed of a four-element antenna array based on L-shaped quarter-wavelength slot antenna elements. Such an antenna element is a planar structure and presents a directional radiation pattern in the azimuth plane. Its maximum radiation direction is toward near the direction of the open end of the slot. As a result, the open ends of the four slot antennas are arranged toward 0, pi/2, pi, and 3pi/2 , respectively. The statuses of these antennas are controlled by some diodes. Consequently, by carefully controlling the diodes, an antenna with several switchable patterns can be achieved. To prove the concept, a 2.4-2.5 GHz switched-beam antenna for WLAN applications is designed and implemented. Its size is 52 mm in square. The antenna possesses eight directional patterns and many nearly omnidirectional patterns in the azimuth plane. The experiment results fully demonstrate the performance of the proposed design. The envelope correlations and the characteristics of the designed antenna are also discussed. Due to the compact size and low manufacture cost, such a design can be a promising solution for digital home applications to overcome multipath problems and increase the transmission data rate.
NEUROExos: A Powered Elbow Exoskeleton for Physical Rehabilitation (2012)

This paper presents the design and experimental testing of the robotic elbow exoskeleton NEUROBOTICS Elbow Exoskeleton (NEUROExos). The design of NEUROExos focused on three solutions that enable its use for poststroke physical rehabilitation. First, double-shelled links allow an ergonomic physical human-robot interface and, consequently, a comfortable interaction. Second, a four-degree-of-freedom passive mechanism, embedded in the link, allows the user's elbow and robot axes to be constantly aligned during movement. The robot axis can passively rotate on the frontal and horizontal planes 30° and 40°, respectively, and translate on the horizontal plane 30 mm. Finally, a variable impedance antagonistic actuation system allows NEUROExos to be controlled with two alternative strategies: independent control of the joint position and stiffness, for robot-in-charge rehabilitation mode, and near-zero impedance torque control, for patient-in-charge rehabilitation mode. In robot-in-charge mode, the passive joint stiffness can be changed in the range of 24-56 N·m/rad. In patient-in-charge mode, NEUROExos output impedance ranges from 1 N·m/rad, for 0.3 Hz motion, to 10 N·m/rad, for 3.2 Hz motion.
<i>amdSYM</i>, a new dominant recyclable marker cassette for<i>Saccharomyces cerevisiae</i> (2012)

Despite the large collection of selectable marker genes available for Saccharomyces cerevisiae, marker availability can still present a hurdle when dozens of genetic manipulations are required. Recyclable markers, counterselectable cassettes that can be removed from the targeted genome after use, are therefore valuable assets in ambitious metabolic engineering programs. In the present work, the new recyclable dominant marker cassette amdSYM, formed by the Ashbya gossypii TEF2 promoter and terminator and a codon-optimized acetamidase gene (Aspergillus nidulans amdS), is presented. The amdSYM cassette confers S. cerevisiae the ability to use acetamide as sole nitrogen source. Direct repeats flanking the amdS gene allow for its efficient recombinative excision. As previously demonstrated in filamentous fungi, loss of the amdS marker cassette from S. cerevisiae can be rapidly selected for by growth in the presence of fluoroacetamide. The amdSYM cassette can be used in different genetic backgrounds and represents the first counterselectable dominant marker gene cassette for use in S. cerevisiae. Furthermore, using astute cassette design, amdSYM excision can be performed without leaving a scar or heterologous sequences in the targeted genome. The present work therefore demonstrates that amdSYM is a useful addition to the genetic engineering toolbox for Saccharomyces laboratory, wild, and industrial strains.
Variable length dominant Gabor local binary pattern (VLD-GLBP) for face recognition (2014)

Gabor filters are one of the most successful methods for face recognition. However they dramatically increase the data volume for face representation. To extract compact and distinctive information, we propose the Variable Length Dominant Gabor Local Binary Pattern (VLD-GLBP) for face recognition. It significantly reduces the face representation data volume whereas the performance is comparable to that of the complex state-of-the-art techniques. Specifically, local binary pattern (LBP) features are first computed from the Gabor images. Then, the most frequently occurred patterns are extracted to form VLD-GLBP. Finally the distance between VLD-GLBPs is computed to realize the face image classification. The experiment results on FERET database verify the efficiency of the proposed VLD-GLBP method.