gebhart/patrepeval huggingface dataset:
A Statistical Approach for Automatic Text Summarization by Extraction (2011)

Automatic Document Summarization is a highly interdisciplinary research area related with computer science as well as cognitive psychology. This Summarization is to compress an original document into a summarized version by extracting almost all of the essential concepts with text mining techniques. This research focuses on developing a statistical automatic text summarization approach, Kmixture probabilistic model, to enhancing the quality of summaries. KSRS employs the K-mixture probabilistic model to establish term weights in a statistical sense, and further identifies the term relationships to derive the semantic relationship significance (SRS) of nouns. Sentences are ranked and extracted based on their semantic relationship significance values. The objective of this research is thus to propose a statistical approach to text summarization. We propose a K-mixture semantic relationship significance (KSRS) approach to enhancing the quality of document summary results. The K-mixture probabilistic model is used to determine the term weights. Term relationships are then investigated to develop the semantic relationship of nouns that manifests sentence semantics. Sentences with significant semantic relationship, nouns are extracted to form the summary accordingly.
Biodegradation of [<sup>3</sup>H]Poly(ε-caprolactone) in the Presence of Active Sludge Extracts (2001)

Poly(epsilon-caprolactone), PCL, is a commercial biodegradable and biocompatible polyester that can be bioassimilated by outdoor microorganisms. For biomedical and environmental applications, monitoring the fate of degradation products in vivo or under environmental conditions is one of the critical steps to evaluate degradation characteristics. [(3)H] radiolabeling is the best method to monitor the fate of degradable polymer chains in contact with complex living systems and to show bioassimilation. Therefore, tritiated PCL was synthesized by chemical modification using anionic activation by reaction with lithium diisopropylamide. The resulting radioactive polymer was characterized and allowed to degrade at 37 degrees C under aerobic conditions in the presence of active sludge. Comparison was made with abiotic hydrolytic degradation in pH = 7.4, 0.13 M phosphate buffer at 37 degrees C. Water-soluble degradation products were assessed by measuring radioactivity in the solution phase. It was shown that biodegradation of PCL started after a few hours and proceeded up to the ultimate stage over ca. 72 days, giving tritiated water (80-90%) and biomass. Radioactivity detection appeared much more sensitive than measurement of CO(2) production or consumption to monitor degradation phenomena. In particular, it showed that the onset of biodegradation occurs earlier than that reported using respirometry.
Cognition in anxious children with attention deficit hyperactivity disorder: a comparison with clinical and normal children. (2007)

Though requiring replication, findings suggest that ANX + ADHD relates to greater cognitive and academic vulnerability than ANX, but may relate to reduced perception of anger.
Improving inter-grain contact in high-T<sub>c</sub>superconducting ceramic sinters (1987)

The authors have attempted to improve the inter-grain contact in sintered samples of the high-Tc superconducting compound YBa2Cu3O7- delta by partial substitution of Y by Bi and Ba by Pb. Both Bi and Pb are found to act as a flux in the sintering process and changes in the morphology of the sintered grains are observed. The Bi substitution is found to reduce the normal state resistivity by almost an order of magnitude while leaving the superconducting properties unchanged.
Bile-Inducible Efflux Transporter from <i>Bifidobacterium longum</i> NCC2705, Conferring Bile Resistance (2009)

Bifidobacteria are normal inhabitants of the human gut. Some strains of this genus are considered health promoting or probiotic, being included in numerous food products. In order to exert their health benefits, these bacteria must overcome biological barriers, including bile salts, to colonize and survive in specific parts of the intestinal tract. The role of multidrug resistance (MDR) transporters in bile resistance of probiotic bacteria and the effect of bile on probiotic gene expression are not fully understood. In the present study, the effect of subinhibitory concentrations of bile on the expression levels of predicted MDR genes from three different bifidobacterial strains, belonging to Bifidobacterium longum subsp. longum, Bifidobacterium breve, and Bifidobacterium animalis subsp. lactis, was tested. In this way, two putative MDR genes whose expression was induced by bile, BL0920 from B. longum and its homolog, Bbr0838, from B. breve, were identified. The expression of the BL0920 gene in Escherichia coli was shown to confer resistance to bile, likely to be mediated by active efflux from the cells. To the best of our knowledge, this represents the first identified bifidobacterial bile efflux pump whose expression is induced by bile.
Optimization of the Micro Channel Heat Sink by Combing Genetic Algorithm with the Finite Element Method (2018)

The design of a micro multi-channel heat sink to achieve the minimum thermal resistance is the purpose of this study. The numerical package is employed by using the genetic algorithm to process the heat dissipation optimization of the micro multi-channel heat sink (the genetic algorithm employs the numerical package). The variables of this optimal design include channel number, channel aspect ratio and the ratio of channel width to pitch, as well as considering the weight of this micro channel heat sink in the optimal design process. Therefore, this optimization is a multi-objective function design. The results show that the thermal resistance is decreased as 0.144 W/K, and the weight of this micro channel heat sink can be decreased, individually or simultaneously.
Generic virtual memory management for operating system kernels (1989)

We discuss the rationale and design of a Generic Memory management Interface, for a family of scalable operating systems. It consists of a general interface for managing virtual memory, independently of the underlying hardware architecture (e.g. paged versus segmented memory), and independently of the operating system kernel in which it is to be integrated. In particular, this interface provides abstractions for support of a single, consistent cache for both mapped objects and explicit I/O, and control of data caching in real memory. Data management policies are delegated to external managers.
Is skin microneedling a good alternative method of various skin defects removal (2018)

Skin microneedling accelerates the process of skin regeneration through the creation of numerous microinjuries which emerge when skin is deeply punctured with very thin needles. The whole procedure evokes various reactions which can be divided into three major phases: inflammation, proliferation, and remodeling. It activates platelet growth factors which are responsible for the stimulation of fibroblasts to produce collagen and elastin. Moreover, skin breakdown enhances penetration of active ingredients. Treatment can be performed with the use of different devices, all equipped with needles of various lengths. Due to the fact that skin microneedling stimulates the synthesis of significant rebuilding and structural skin elements (collagen, elastin, proteoglycan), it is used in the treatment of many skin defects of different etiologies (e.g., photoaging, wrinkles, loss of elasticity, hypo- or hypertrophic scars, pigmentation changes, infraorbital dark circles, teleangiectasia, stretch marks, cellulite, alopecia, and vitiligo). In order to accelerate postsurgical regeneration and/or to enhance effects, microneedling is combined with the application of UV light (photodynamic therapy with ALA), LED light, platelet-rich plasma, chemical peels, stem cells, retinoids and other pharmaceuticals, and vitamins. High effectiveness, limited number of side effects, and short recovery time, make skin microneedling a popular cosmetic, and medical treatment.
Relationship Between Dairy Product Consumption and Incidence of IDDM in Childhood in Italy (1994)

The results indicate that there is a relationship, even in a single country, between dairy product consumption and the incidence of IDDM that is confined to fluid milk consumption. Cows' milk may contain a triggering factor for the development of diabetes, but the high incidence of IDDM in Sardinia and in other countries worldwide cannot be explained simply by the quantity of fluid cows' milk consumed.
Study on micro-mouse maze searching based on C8051F120 (2011)

Embedded micro-controllers, sensors and electrical and mechanical moving parts was used in micro- mouse, which is an intelligent walking robot, the micro-mouse can walk and memory maze information , and automatically select the shortest path, use the corresponding algorithm to quickly reach destination. Hardware and software design of micro-mouse based on the C8051F120 was discussed, also with the experimental results.
Roles of Proteoglycans and Glycosaminoglycans in Wound Healing and Fibrosis (2015)

A wound is a type of injury that damages living tissues. In this review, we will be referring mainly to healing responses in the organs including skin and the lungs. Fibrosis is a process of dysregulated extracellular matrix (ECM) production that leads to a dense and functionally abnormal connective tissue compartment (dermis). In tissues such as the skin, the repair of the dermis after wounding requires not only the fibroblasts that produce the ECM molecules, but also the overlying epithelial layer (keratinocytes), the endothelial cells, and smooth muscle cells of the blood vessel and white blood cells such as neutrophils and macrophages, which together orchestrate the cytokine-mediated signaling and paracrine interactions that are required to regulate the proper extent and timing of the repair process. This review will focus on the importance of extracellular molecules in the microenvironment, primarily the proteoglycans and glycosaminoglycan hyaluronan, and their roles in wound healing. First, we will briefly summarize the physiological, cellular, and biochemical elements of wound healing, including the importance of cytokine cross-talk between cell types. Second, we will discuss the role of proteoglycans and hyaluronan in regulating these processes. Finally, approaches that utilize these concepts as potential therapies for fibrosis are discussed.
The role of T cells in anti-herpes simplex virus immunity. I. Induction of antigen-specific cytotoxic T lymphocytes. (1977)

Mice infected with herpes simplex virus develop little or no cytotoxic T lymphocyte (CTL) response. However, in lymph nodes (LN's) draining a local site infected with HSV, antigen-specific CTL precursors are sensitized, which upon transfer to in vitro culture conditions develop within 72 hr into effective CTL. The in vivo blockade of CTL differentiation can be overcome by cyclophosphamide, suggesting that a cyclophosphamide-sensitive mechanism blocks the in vivo generation of HSV-immune CTL. The cytolytic activity of HSV-immune CTL is H-2 restricted and antigen specific. Thus CTL sensitized toward HSV type 1 discriminate between syngeneic targets infected with either the immunologic HSV variant type 1 or type 2 (and vice versa). H-2-matched target cells exposed for 30 min to infectious HSV are lysed within 60 min of contact with CTL. Since HSV replication is believed to require more than 4 to 5 hr, the data suggest that either the expression of HSV-dependent "early proteins" takes place within 30 to 90 min or cell membrane-integrated HSV virion represents the target antigen of CTL.
Enzyme Redundancy and the Importance of 2-Oxoglutarate in Higher Plant Ammonium Assimilation (2000)

The assimilation of inorganic N, in the form of ammonia, onto C skeletons for the production of amino acids is one of the most important biochemical processes in plants. In an actively growing plant, N is taken up as nitrate and to a lesser extent as ammonia. Nitrate is reduced in the cytoplasm by
Synthesis of Amino Acid Cofactor in Cysteine Dioxygenase Is Regulated by Substrate and Represents a Novel Post-translational Regulation of Activity (2008)

Cysteine dioxygenase (CDO) catalyzes the conversion of cysteine to cysteinesulfinic acid and is important in the regulation of intracellular cysteine levels in mammals and in the provision of oxidized cysteine metabolites such as sulfate and taurine. Several crystal structure studies of mammalian CDO have shown that there is a cross-linked cofactor present in the active site of the enzyme. The cofactor consists of a thioether bond between the gamma-sulfur of residue cysteine 93 and the aromatic side chain of residue tyrosine 157. The exact requirements for cofactor synthesis and the contribution of the cofactor to the catalytic activity of the enzyme have yet to be fully described. In this study, therefore, we explored the factors necessary for cofactor biogenesis in vitro and in vivo and examined what effect cofactor formation had on activity in vitro. Like other cross-linked cofactor-containing enzymes, formation of the Cys-Tyr cofactor in CDO required a transition metal cofactor (Fe(2+)) and O(2). Unlike other enzymes, however, biogenesis was also strictly dependent upon the presence of substrate. Cofactor formation was also appreciably slower than the rates reported for other enzymes and, indeed, took hundreds of catalytic turnover cycles to occur. In the absence of the Cys-Tyr cofactor, CDO possessed appreciable catalytic activity, suggesting that the cofactor was not essential for catalysis. Nevertheless, at physiologically relevant cysteine concentrations, cofactor formation increased CDO catalytic efficiency by approximately 10-fold. Overall, the regulation of Cys-Tyr cofactor formation in CDO by ambient cysteine levels represents an unusual form of substrate-mediated feed-forward activation of enzyme activity with important physiological consequences.
Global-scale<i>P</i>wave tomography optimized for prediction of teleseismic and regional travel times for Middle East events: 2. Tomographic inversion (2011)

[1] We construct a model of three-dimensional P wave velocity structure in the crust and mantle that is global in extent, but with detailed upper mantle heterogeneities throughout the greater Middle East region. Fully three-dimensional ray tracing is employed to achieve accurate travel time predictions of P and Pn arrivals, requiring the characterization of irregular and discontinuous boundaries. Therefore, we explicitly represent undulating seismic discontinuities in the crust and upper mantle within a spherical tessellation modeling framework. The tessellation-based model architecture is hierarchical in that fine node sampling is achieved by recursively subdividing a base level tessellation. Determining the required node spacing to effectively model a given set of data is problematic, given the uneven sampling of seismic data and the differing wavelengths of actual seismic heterogeneity. To address this problem, we have developed an inversion process called Progressive Multilevel Tessellation Inversion (PMTI) that exploits the hierarchical nature of the tessellation-based design and allows the data to determine the level of model complexity. PMTI serves as an alternative to existing multiresolution approaches and robustly images regional trends while allowing localized details to emerge where resolution is sufficient. To demonstrate our complete modeling concept, we construct a velocity model based on teleseismic P travel time data for global events and regional Pn travel time data for events occurring throughout the Middle East. Input data are a product of the statistical procedure called Bayesloc that simultaneously models all components of a multievent system including event locations, origin times, and arrival times (described in the Myers et al. (2011) companion paper). The initial tomographic image provides a new glimpse of the complex upper mantle velocity anomalies associated with the convergence of the Arabian and Indian plates with Eurasia. More important for event monitoring, the model accurately predicts both teleseismic and regional travel times for events occurring within the Middle East region.
A modified dinucleotide for site-specific RNA-labelling by transcription priming and click chemistry (2013)

An improved strategy for RNA labelling using an alkyne-carrying dinucleotide is reported. This involves near-quantitative priming by phage RNA-polymerases followed by conjugation of different labels using click chemistry. Moreover, these transcripts bear a ligation compatible 5'-end, and thus through ligation the terminal label can be transformed to an internal one.
Interaction of Flavodoxin with Cobalamin-Dependent Methionine Synthase (2000)

Cobalamin-dependent methionine synthase catalyzes the transfer of a methyl group from methyltetrahydrofolate to homocysteine, forming tetrahydrofolate and methionine. The Escherichia coli enzyme, like its mammalian homologue, is occasionally inactivated by oxidation of the cofactor to cob(II)alamin. To return to the catalytic cycle, the cob(II)alamin forms of both the bacterial and mammalian enzymes must be reductively remethylated. Reduced flavodoxin donates an electron for this reaction in E. coli, and S-adenosylmethionine serves as the methyl donor. In humans, the electron is thought to be provided by methionine synthase reductase, a protein containing a domain with a significant degree of homology to flavodoxin. Because of this homology, studies of the interactions between E. coli flavodoxin and methionine synthase provide a model for the mammalian system. To characterize the binding interface between E. coli flavodoxin and methionine synthase, we have employed site-directed mutagenesis and chemical cross-linking using carbodiimide and N-hydroxysuccinimide. Glutamate 61 of flavodoxin is identified as a cross-linked residue, and lysine 959 of the C-terminal activation domain of methionine synthase is assigned as its partner. The mutation of lysine 959 to threonine results in a diminished level of cross-linking, but has only a small effect on the affinity of methionine synthase for flavodoxin. Identification of these cross-linked residues provides evidence in support of a docking model that will be useful in predicting the effects of mutations observed in mammalian homologues of E. coli flavodoxin and methionine synthase.
Assessment of new radioimmunoassay kit for determining urinary albumin at low concentrations: comparison with radial immunodiffusion. (1986)

The assay characteristics of a new radioimmunoassay kit for determining urinary albumin at low concentrations were studied. The sensitivity for urinary albumin was 2 mg/l, the analytical range 2 to 40 mg/l, and interassay coefficient of variation less than 12%. In a method comparison study entailing diabetic urine samples covering an albumin concentration of 2 to 150 mg/l the kit compared adequately with radial immunodiffusion (mean difference between methods = 2 mg/l; residual standard deviation = 4.6 mg/l), absolute variation between methods increasing with the concentration. The kit required much less skill than radial immunodiffusion but its capital and running cost were higher.
Characterization of coreless printed circuit board (PCB) transformers (2003)

In this paper, coreless printed-circuit-board transformers are characterized. A range of coreless PCB transformers with different geometric parameters have been fabricated and tested. Based on a recently reported analytic method, the self inductances of these transformers are calculated. This analytical method is also extended to cover the prediction of the transformers' mutual inductance. All calculated parameters have been confirmed with measurements for the frequency range from 100 kHz to 30 MHz. These results provide useful information for the optimal design of coreless PCB transformers.
Angle and space diversity comparisons in different mobile radio environments (1999)

Two types of high-gain multibeam antennas: (1) 24, 15/spl deg/ vertically polarized (Vpol) beams, and (2) 12, 30/spl deg/ Vpol beams were tested and compared to traditional sector antenna configurations. The antennas were tested in dense urban and rural mobile radio environments. A vehicle equipped with a mobile transmitter was driven in the coverage area while the received signal strength (RSS) was recorded on multiple receiver channels attached to multibeam and sector antennas at the base site. The RSS data recorded included fast (Rayleigh) fading and was averaged into local means based on the mobile's position/speed. The fast fading was extracted from the recorded RSS, and the fading distributions of the two multibeam antennas tested were studied in two distinctly different mobile environments. Fading cumulative distributions for the angular diverse antennas were compared to those of spatially diverse antennas. Angular diversity gain was calculated and compared to traditional space diversity in these mobile environments. Results indicate that angular diversity performance is comparable to space diversity in urban environments (/spl sim/8 dB). Rural tests typically suggest that both space diversity and angular diversity provide little or no (<2 dB) improvement in fading reduction. A description of the experiment, data reduction and analyses, and calculation of diversity gain are presented.
The Switchblade Mentality and your Child (1977)

I am sure you will forgive me if I do not deliver a formal lecture on an occasion like this. It would be easy to be heavy and serious with a theme such as the one chosen for this week, and the title “The Switchblade Mentality” scarcely leads you to expect an after dinner entertainment. I always feel mildly disappointed after speaking on topics like this when kind listeners come up and say “Thank you, I enjoyed that”.
Ivermectin and filariasis (2003)

Ivermectin, a parasiticide that long ago proved its worth in veterinary medicine, became one of the most effective tools for control programs against human filarial diseases in the 1980s. It is provided at no cost, is effective against microfilariae (blocking their transmission) and can be administered annually as a single oral dose with virtually no side-effects: these considerations led the WHO to officially declare eradicable two endemic filarial diseases (among the major endemic diseases worldwide), onchocerciasis and lymphatic filariasis.