gebhart/patrepeval huggingface dataset:
Boosting Autofermentation Rates and Product Yields with Sodium Stress Cycling: Application to Production of Renewable Fuels by Cyanobacteria (2010)

Sodium concentration cycling was examined as a new strategy for redistributing carbon storage products and increasing autofermentative product yields following photosynthetic carbon fixation in the cyanobacterium Arthrospira (Spirulina) maxima. The salt-tolerant hypercarbonate strain CS-328 was grown in a medium containing 0.24 to 1.24 M sodium, resulting in increased biosynthesis of soluble carbohydrates to up to 50% of the dry weight at 1.24 M sodium. Hypoionic stress during dark anaerobic metabolism (autofermentation) was induced by resuspending filaments in low-sodium (bi)carbonate buffer (0.21 M), which resulted in accelerated autofermentation rates. For cells grown in 1.24 M NaCl, the fermentative yields of acetate, ethanol, and formate increase substantially to 1.56, 0.75, and 1.54 mmol/(g [dry weight] of cells·day), respectively (36-, 121-, and 6-fold increases in rates relative to cells grown in 0.24 M NaCl). Catabolism of endogenous carbohydrate increased by approximately 2-fold upon hypoionic stress. For cultures grown at all salt concentrations, hydrogen was produced, but its yield did not correlate with increased catabolism of soluble carbohydrates. Instead, ethanol excretion becomes a preferred route for fermentative NADH reoxidation, together with intracellular accumulation of reduced products of acetyl coenzyme A (acetyl-CoA) formation when cells are hypoionically stressed. In the absence of hypoionic stress, hydrogen production is a major beneficial pathway for NAD(+) regeneration without wasting carbon intermediates such as ethanol derived from acetyl-CoA. This switch presumably improves the overall cellular economy by retaining carbon within the cell until aerobic conditions return and the acetyl unit can be used for biosynthesis or oxidized via respiration for a much greater energy return.
Integer sorting on shared-memory vector parallel computers (1998)

Article Free Access Share on Integer sorting on shared-memory vector parallel computers Authors: Kenji Suehiro NEC Corporation, 4-1-1 Miyazaki, Miyamae-ku, Kawasaki, 216-8555 Japan NEC Corporation, 4-1-1 Miyazaki, Miyamae-ku, Kawasaki, 216-8555 JapanView Profile , Hitoshi Murai NEC Corporation, 4-1-1 Miyazaki, Miyamae-ku, Kawasaki, 216-8555 Japan NEC Corporation, 4-1-1 Miyazaki, Miyamae-ku, Kawasaki, 216-8555 JapanView Profile , Yoshiki Seo NEC Corporation, 4-1-1 Miyazaki, Miyamae-ku, Kawasaki, 216-8555 Japan NEC Corporation, 4-1-1 Miyazaki, Miyamae-ku, Kawasaki, 216-8555 JapanView Profile Authors Info & Claims ICS '98: Proceedings of the 12th international conference on SupercomputingJuly 1998 Pages 313–320https://doi.org/10.1145/277830.277904Online:13 July 1998Publication History 7citation280DownloadsMetricsTotal Citations7Total Downloads280Last 12 Months5Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Cancer control in Lower Utopia (2000)

In an attempt to demonstrate what is actually possible, the author developed the concept of the ideal cancer organisation, the Cancer Society of Lower Utopia. The activities of the Society are presented. (non-author abstract)
The Effect of Linkedin on Deception in Resumes (2012)

This study explores how Linkedin shapes patterns of deception in resumes. The general self-presentation goal to appear favorably to others motivates deception when one's true characteristics are inconsistent with their desired impression. Because Linkedin makes resume claims public, deception patterns should be altered relative to traditional resumes. Participants (n=119) in a between-subjects experiment created resumes in one of three resume settings: a traditional (offline) resume, private Linkedin profiles, or publicly available Linkedin profiles. Findings suggest that the public nature of Linkedin resume claims affected the kinds of deception used to create positive impressions, but did not affect the overall frequency of deception. Compared with traditional resumes, Linkedin resumes were less deceptive about the kinds of information that count most to employers, namely an applicant's prior work experience and responsibilities, but more deceptive about interests and hobbies. The results stand in contrast to assumptions that Internet-based communication is more deceptive than traditional formats, and suggests that a framework that considers deception as a resource for self-presentation can account for the findings.
Über C‐substituierte Piperazinderivate Untersuchungen über Synthetische Arzneimittel, 10. Mitteilung (1962)

Abstract Es wird über die Darstellung verschiedener bisher unbekannter Piperazin‐2‐carbonsäureester und 2‐Hydroxymethyl‐piperazine sowie der daraus abgeleiteten α‐(2‐Piperazinyl)‐benzhydrole und 2‐Benzhydryloxymethyl‐piperazine berichtet.
Recognising User Identity in Twitter Social Networks via Text Mining (2013)

Social networks have become a convenient and effective means of communication in recent years. Many people use social networks to communicate, lead, and manage activities, and express their opinions in supporting or opposing different causes. This has brought forward the issue of verifying the owners of social accounts, in order to eliminate the effect of any fake accounts on the people. This study aims to authenticate the genuine accounts versus fake account using writeprint, which is the writing style biometric. We first extract a set of features using text mining techniques. Then, gtraining of a supervised machine learning algorithm to build the knowledge base is conducted. The recognition procedure starts by extracting the relevant features and then measuring the similarity of the feature vector with respect to all feature vectors in the knowledge base. Then, the most similar vector is identified as the verified account.
Multiple adaptive mechanisms affect asparagine synthetase substrate availability in asparaginase-resistant MOLT-4 human leukaemia cells (2001)

Childhood acute lymphoblastic leukaemia is treated by combination chemotherapy with a number of drugs, almost always including the enzyme L-asparaginase (ASNase). Although the initial remission rate is quite high, relapse and associated drug resistance remain a problem. In vitro studies have demonstrated an adaptive increase in asparagine synthetase (AS) expression in ASNase-resistant cells, which is believed to permit ASNase-resistant human leukaemia cells to survive in vivo. The present results, obtained with ASNase-sensitive and -resistant human MOLT-4 leukaemia cell lines, illustrate that several other adaptive processes occur to provide sufficient amounts of the AS substrates, aspartate and glutamine, required to support this increased enzymic activity. In both cell populations, aspartate is derived almost exclusively from intracellular sources, whereas the necessary glutamine arises from both intracellular and extracellular sources. Transport of glutamine into ASNase-resistant cells is significantly enhanced compared with the parental cells, whereas amino acid efflux (e.g. asparagine) is reduced. Most of the adaptive change for the amino acid transporters, Systems A, ASC and L, is rapidly (12 h) reversed following ASNase removal. The enzymic activity of glutamine synthetase is also enhanced in ASNase-resistant cells by a post-transcriptional mechanism. The results demonstrate that there are several sites of metabolic adaptation in ASNase-treated leukaemia cells that serve to promote the replenishment of both glutamine and asparagine.
`Captain Samuel Holland' Rose (1991)

Captain Samuel Holland' is a winterhardy, pillar-type rose with a trailing growth habit and light-red flowers.The plant flowers freely and recurrently and is resistant to powdery mildew [Sphaerotheca pannosa (Wallr.Ex Fr.) Lev.] and blackspot (Diplocarpon rosae Wolf.).petal surface colors are classified as 66B and 66D, respectively, in the red-purple group, 'Captain Samuel Holland' has been tested at Ottawa, Ontario, for 5 years (Table 1) and for an additional 3 years at L'Assomption.Both sites are in the Canadian plant hardi-
Single layer chemical vapor deposition photoresist for 193 nm deep ultraviolet photolithography (1998)

The chemical vapor deposition resist film plasma polymerized methyl silane (PPMS) can be used as a single layer photoresist for optical lithography at 248 and 193 nm wavelengths. Upon exposure, the PPMS undergoes efficient photo oxidation in the presence of air to yield a siloxane network (PPMSO) giving patterns that can be dry developed using a chlorine-HBr plasma. After dry development, the PPMSO can be used to transfer a pattern through organic low κ materials, or can be converted to a silicon dioxide hardmask using a conventional resist stripper, then used to transfer patterns into polysilicon.
A flexural in-line actuator for magnetic recording disk drives (1991)

An actuator for magnetic recording disk drives based on flexures and coupled to a voice coil motor (VCM) was developed for a 3.5-in disk drive. The design and performance of this system is described. This high-performance flexural actuator has been shown to have unique advantages over conventional designs, demonstrated in a magnetic recording disk file prototype.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Coagulation of a carboxylated latex with polyethylenimine (1974)

The coagulation of a carboxylated styrene/butadiene latex, using polyethylenimine (PEI), was investigated using a light transmission technique and microelectrophoresis. Two charge-reversal regions were observed as the polyelectrolyte concentration was increased from 10−4 to 1 wt-%. During each of these regions, the latex was destabilized and then restabilized. The addition of HCI to the PEI solution can eliminate the second coagulation region completely while the first region is hardly affected. The second region was found to be dependent on the degree of protonation of the polyethylenimine and occurred in a pH range where the latex surface charge increases drastically as a function of increasing pH due to the ionization of surface carboxyl groups.
Optical gain of strained GaAsSb/GaAs quantum-well lasers: A self-consistent approach (2000)

We present a self-consistent model for the band structure and optical gain spectrum of GaAs1−xSbx/GaAs quantum-well (QW) lasers with carrier population. Experimental data indicate that this material system has a type-II QW configuration. By fitting the experimental photoluminescence data from various groups using our proposed empirical model, which assumes that 90% of the band-gap bowing parameter (1.2 eV) appears in the valence band, we find that the unstrained valence band edge discontinuity ratio Qv0 is close to 0.9 for an arbitrary Sb mole composition x of GaAs1−xSbx/GaAs QWs and the QW structure becomes type-II when the compressive strain induced band-edge shifts are taken into account. We show that for type-II QWs the self-consistent solution, which solves the Schrödinger equation and Poisson equation simultaneously, is necessary. Due to the free-carrier screening effect in the self-consistent potential, the electrons are attracted toward the barrier–well interfaces by the holes in the wells, and, therefore, sufficient gain can be achieved for lasing action with type-II QWs. Our theoretical results are compared with experimental data of laser operation wavelength and modal gain, with reasonable agreement. Our model will be important for modeling of type-II QW lasers and useful for design of GaAsSb/GaAs QW vertical-cavity surface-emitting lasers.
Trajectory clustering for coastal surveillance (2007)

Achieving superior situation awareness is a key task for military, as well as civilian, decision makers. Today, automatic systems provide us with an excellent opportunity for assisting the human decision maker in achieving this awareness. Due to the potential of information overload one important aspect is to understand where to focus attention. Anomaly detection is concerned with finding deviations from normalcy and it is an increasingly important topic when providing decision support, since it can give hints towards where more analysis is needed. In this paper we explore trajectory clustering as a means for representing normal behavior in a coastal surveillance scenario. Trajectory clustering however suffers from some drawbacks in this type of setting and we therefore propose a new approach, spline-based clustering, with a potential for solving the task of representing the normal course of events.
Chromatographic preparation and in vitro properties of albumin from human plasma. (1984)

Albumin has been purified by chromatography using standardized procedures with different starting materials depending on previous fractionation. Plasma can be used directly after cryoprecipitation and Factor IX adsorption or after isolation of IgG. The plasma was centrifuged and then desalted on Sephadex G-25 Coarse, the pH was adjusted, and the euglobulins were precipitated before ion-exchange chromatography on DEAE- and CM-Sepharose CL-6B. This was followed by concentration by ultrafiltration, gel filtration on Sephacryl S-200, and final concentration and formulation. The albumin obtained was 99% pure and contained less than 1% of aggregated protein.
Cover Picture: Synthesis and Water Solubility of Novel Fullerene Bisadduct Derivatives (Eur. J. Org. Chem. 24/2003) (2003)

Abstract The cover picture shows water‐soluble fullerene derivatives floating in the Trieste bay, Italy, with the magnificent Miramare Castle, built between 1856 and 1860 by Maximilian of Habsburg, in the background. Details of the synthesis and water solubility of novel fullerene bisadduct derivatives are discussed in the article by M. Prato et al. on p. 4741 ff.
Part Fabrication Using Laser Machining and Welding (2018)

This paper describes the current work on a laser cutting and welding system for\nthe fabrication of prototype parts in mild and .. stainless steels. The relationship\nto other rapid prototyping systems and to laminated tool production techniques is\ndiscussed, the progress to date is described. Difficulties with current welding\nprocedures are outlined and alternative joining techniques are considered.
Photoacoustic phase signatures of closed cracks (1982)

The photoacoustic phase signatures of closed cracks are calculated and compared with experimental observations. The differential signals from near subsurface lateral cracks are advanced in phase by 45° with respect to the background signal, in contrast to the 45° lag in phase observed for a near lower surface step.
The Notch target genes <i>Hey1</i> and <i>Hey2</i> are required for embryonic vascular development (2004)

The Delta-Notch signaling pathway plays a central role in the development of most vertebrate organs. The Hey family of bHLH transcription factors are direct targets of Notch signaling. Loss of Hey2 in the mouse leads to cardiac defects with high postnatal lethality. We have now generated a mouse Hey1 knockout that has no apparent phenotypic defect. The combined loss of Hey1 and Hey2, however, results in embryonic death after embryonic day 9.5 (E9.5) with a global lack of vascular remodeling and massive hemorrhage. Initial vasculogenesis appears unaffected, but all subsequently developing major vessels in the embryo and yolk sac are either small or absent. Furthermore, the placental labyrinth completely lacks embryonic blood vessels. Similar vascular defects are observed in Jagged1 and Notch1 knockout mice. In the latter we found Hey1 and Hey2 expression in yolk sacs to be strongly reduced. Remaining large arteries in both Notch1 and Hey1/Hey2 knockout mice fail to express the arterial endothelial markers CD44, neuropilin1, and ephrin-B2. This indicates that Hey1/Hey2 are essential transducers of Notch signals in cardiovascular development that may mediate arterial cell fate decision.
Gene and cDNA cloning and characterization of the mouse V3/V1b pituitary vasopressin receptor (1999)

The gene of the mouse V3/V1b receptor was identified by homology cloning. One of the genomic clones contained the entire coding sequence. The cDNA presented high identity with rat (92%) and human (84%) sequences. Southern blot analysis indicated the existence of a single gene. Tissue distribution was studied by RT-PCR. The major site of expression was the pituitary. A faint signal was also present in hypothalamus, brain, adrenal, pancreas and colon. The mouse corticotroph cell line, AtT20, did not express the transcript. In order to confirm the identity of the sequence, the V3/V1b receptor cDNA was cloned and stably expressed in CHO-AA8 Tet-Off cells under the control of tetracycline. When transfected cells were treated with arginine vasopressin (AVP), inositol phosphate production increased in a dose-dependent manner, indicating that the V3/V1b receptor couples to phospholipase C. Moreover, AVP did not stimulate cAMP production. Binding studies with [3H]AVP indicated that the affinity of the mouse V3/V1b receptor (Kd=0.5 nM) is similar to that reported for rat and human receptors. The rank order of potency established in competition binding experiments with different analogues was representative of a V3/V1b profile, distinct from V1a and V2. However, significant differences were found between human and mouse receptors tested in parallel. Thus the pharmacology of V3/V1b receptors can not be transposed among different species.
Clinical and Molecular Genetics of ADHD and Tourette Syndrome (2001)

ADHD is a polygenic disorder due to the additive effect of genes affecting dopamine, norepinephrine, serotonin, GABA, and other neurotransmitters. Some of the specific loci involved are dopamine genes--DRD2, DRD4, DRD5, and the dopamine transporter; norepinephrine (NE) and epinephrine (EPI) genes--dopamine beta-hydroxylase, ADRA2A, ADRA2C, PNMT, norepinephrine transporter, MAOA, COMT; serotonin genes--TDO2, HTR1A, HTR1DA, serotonin transporter; GABA genes--GABRB3; androgen receptor and other genes. This model is consistent with all of the present knowledge about ADHD including (a) the increased frequency of ADHD in the relatives of ADHD probands, (b) the presence of a wide spectrum of comorbid behaviors (depression, anxiety, learning, conduct, oppositional-defiant, conduct and substance abuse disorders) in ADHD probands and their relatives on both parental sides, (c) the close relationship to Tourette syndrome (TS), (d) the failure to find the genes for TS using linkage analysis, (e) the brain imaging studies showing hypometabolism of the frontal lobes, (f) the relationship between dopamine D2 receptor density and regional blood flow, (g) the correlation between tics and dopamine D2 receptor density in TS, (h) the motor hyperactivity of dopamine transporter and dopamine D3 receptor gene knockout mice, (i) the LeMoal and Shaywitz dopamine deficiency animal models of ADHD, (j) the NE models of ADHD, (k) the failure to explain ADHD on the basis of any single neurotransmitter defect, (l) the response of ADHD to dopamine and alpha 2-adrenergic agonists, (m) the small percentage of the variance of specific behaviors accounted for by each gene, and numerous other aspects of ADHD. The implications of the polygenic model for the understanding, diagnosis and treatment of ADHD and TS, as well as other psychiatric disorders, are reviewed.
Making graphs reducible with controlled node splitting (1997)

Several compiler optimizations, such as data flow analysis, the exploitation of instruction-level parallelism (ILP), loop transformations, and memory disambiguation, require programs with reducible control flow graphs. However, not all programs satisfy this property. A new method for transforming irreducible control flow graphs to reducible control flow graphs, called Controlled Node Splitting (CNS), is presented. CNS duplicates nodes of the control flow graph to obtain reducible control flow graphs. CNS results in a minimum number of splits and a minimum number of duplicates. Since the computation time to find the optimal split sequence is large, a heuristic has been developed. The results of this heuristic are close to the optimum. Straightforward application of node splitting resulted in an average code size increase of 235% per procedure of our benchmark programs. CNS with the heuristic limits this increase to only 3%. The impact on the total code size of the complete programs is 13.6% for a straightforward application of node splitting. However, when CNS is used, with the heuristic the average growth in code size of a complete program dramatically reduces to 0.2%
Amphotericin B Lipid Complex (Ablc™): A Molecular Rationale for the Attenuation of Amphotericin B Related Toxicities (1993)

Despite its associated toxicities, amphotericin B remains the drug of first choice for a variety of systemic fungal infections that were invariably fatal prior to its introduction. A natural product of Streptomyces, the structure of this compound is quite remarkable: it is approximately the length of a phospholipid molecule but possesses along its long axis both a polyhydroxyl and polyene hydrocarbon backbone. These domains of opposite polarity imbue amphotericin with unusual solubility properties, appear to be the key to its destruction of cells via membrane perturbation and depletion of transmembrane ion gradients, and have attracted, over the years, the attentions of a plethora of physical chemists interested in drug-lipid interactions. The association of amphotericin with liposome membranes has been studied extensively and has been related to lipid composition, radius of curvature, physical state, the amount and type of sterol present, and in our hands, drug/lipid ratios (1).
Comparison of Gas-Turbine Cycles for Space Applications (1960)

On the basis of the radiator area required for rejecting cycle waste heat, Rankine vapor cycles are far superior to the basic Brayton gas cycle for space turbogenerating powerplants. The present analysis considers modifications of the basic Brayton cycle and compares the modified cycles to the basic cycle with radiator area as the criterion of merit. The results indicate that reductions in radiator area attainable by modifying the basic Brayton cycle are small, and thus the competitive position of gasturbine cycles relative to Rankine vapor cycles is unchanged.
Inappropriate Shocks in Patients with ICDs: Single Chamber versus Dual Chamber (2013)

It was determined that there was no clear evidence of superiority of any of the devices evaluated.
Clinical outcomes following IVUS-guided stent deployment in a community hospital. (2004)

In this population, IVUS-guided stent deployment does not appear to reduce either the need for TVR or overall cardiovascular mortality at 6 months. The added expense of IVUS does not appear to be warranted.