gebhart/patrepeval huggingface dataset:
TREATMENT OF ACUTE LUMBAGO (2008)

Objective: To determine whether concomitant use of vitamins B1, B6, B12 along with low dose of diclofenac sodium causesquicker pain relief in patients of acute lumbago compared with diclofenac sodium alone. Design: A randomized clinical trial. Setting: SurgicalDepartment of C M H Attock. Period: From September 2004 to August 2005 Patients & Methods: A total of 50 patients were selected forthe study. The patients complaints were of acute lumbago of less than 3 days duration with severe impairments of movements. The age groupof patients was between 20 and 65 years. The patients were randomly assigned into two groups. Group I was prescribed tablet diclofenacsodium 25mg along with vitamin B-complex containing combination of 100mg thiamine nitrate (B1), 100mg pyridoxine hydrochloride (B6), and200mcg cyanocobalmine (B12) three times a day. Group II patients were prescribed 25mg of tablet diclofenac sodium alone. Improvement inthe intensity of pain at rest and during movements (as assessed by the patients) was noted in accordance to visual analogue scale 1 to 10.The effectiveness of diclofenac sodium in combination with vitamin-B complex with diclofenac sodium alone was judged on the basis of extentof pain relief after 7 days of treatment. Results: A total of 25 patients were treated with combination of diclofenac sodium & vitamin-B complex(Group I) and 25 were treated with diclofenac sodium alone (Group II). As far as the extent of pain relief in first 7 days is considered, 22 patients(88%) belonging to group I and 10 patients (12%) belonging to group II had an excellent pain relief and were able to carry on with their normalroutine activities. Remaining 3 patients in group I were completely relieved of pain in next 3 days while 15 patients in group II had to completeanother 10 days for complete cure. To test the statistical significance of the result chi-square test was applied and the result showed thatpatients of Group I responded significantly well to the treatment as compared to those in Group II. Conclusion: Using the parameters of painrelief and movements of vertebral column, the combination of diclofenac sodium & vitamin-B complex was found to be more effective modeof treatment as the duration of treatment and the dosage of diclofenac sodium was less and also relief of pain was more rapid.
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: the GOLD science committee report 2019 (2019)

Precision medicine is a patient-specific approach that integrates all relevant clinical, genetic and biological information in order to optimise the therapeutic benefit relative to the possibility of side-effects for each individual. Recent clinical trials have shown that higher blood eosinophil counts are associated with a greater efficacy of inhaled corticosteroids (ICSs) in chronic obstructive pulmonary disease (COPD) patients. Blood eosinophil counts are a biomarker with potential to be used in clinical practice, to help target ICS treatment with more precision in COPD patients with a history of exacerbations despite appropriate bronchodilator treatment.The Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 pharmacological treatment algorithms, based on the ABCD assessment, can be applied relatively easily to treatment-naive individuals at initial presentation. However, their use is more problematic during follow-up in patients who are already on maintenance treatment. There is a need for a different system to guide COPD pharmacological management during follow-up.Recent large randomised controlled trials have provided important new information concerning the therapeutic effects of ICSs and long-acting bronchodilators on exacerbations. The new evidence regarding blood eosinophils and inhaled treatments, and the need to distinguish between initial and follow-up pharmacological management, led to changes in the GOLD pharmacological treatment recommendations. This article explains the evidence and rationale for the GOLD 2019 pharmacological treatment recommendations.
Structural determination of the capsular polysaccharide of <i>Streptococcus</i><i>pneumoniae</i> type-19 (19F) (1980)

The structure of the Pneumococcus type-19 (19F) capsular polysaccharide has been reinvestigated using nmr spectroscopy. It is composed of residues of 2-acetamido-2-deoxy-D-mannose, D-glucose, L-rhamnose, and phosphate in the molar ratio of 1:1:1:1. The polysaccharide is linear and is composed of the above components in a repeating unit of the following structure:→ 4)-β-D-ManNAcp-(1 → 4)-α-D-Glcp-(1→ 2)-α-L-Rhap-(1-PO 4 − )→.
Excited state contamination in nucleon structure calculations (2012)

Among the sources of systematic error in nucleon structure calculations is contamination from unwanted excited states. In order to measure this systematic error, we vary the operator insertion time and source-sink separation independently. We compute observables for three source-sink separations between 0.93 fm and 1.39 fm using clover-improved Wilson fermions and pion masses as low as 150 MeV. We explore the use of a two-state model fit to subtract off the contribution from excited states.
Maternal Effects of theshort integumentMutation on Embryo Development inArabidopsis (1996)

Maternal gene products deposited in an animal egg determine the polarity of embryonic axes and regulate embryonic cell-cell communication important for morphogenesis. Here we report the first maternal-effect embryo-defective mutation discovered in a plant. Recessive mutations in the SHORT INTEGUMENT (SIN1) gene in Arabidopsis were previously shown to influence ovule development and flowering time. Here we show that a sin1 mutation has a pronounced maternal effect on zygotic embryo development. A homozygous sin1 mutant embryo is normal when nursed by a sin1/+ heterozygous maternal sporophyte. Strikingly, a sin1 or a sin1/+ embryo that is nursed by a sin1 homozygous maternal sporophyte develops morphogenetic defects in the apical-basal and radial axes. The defects resemble those seen in some zygotic-effect embryonic pattern formation mutants. These results imply that in maternal cells the SIN1 gene either codes for or controls the production of a diffusible morphogen necessary for proper zygotic embryogenesis.
Synthesis and atomic-level characterization of Ni nanoparticles in Al2O3 matrix (2002)

Single domain magnetic nickel nanocrystals were embedded in alumina matrix using a pulsed-laser deposition technique. Structural characterization carried out at the atomic level using scanning transmission electron microscopy with atomic number contrast (STEM-Z) in conjunction with electron energy loss spectroscopy have revealed that the Ni particles are well separated and have interfaces with the host matrix that are atomically sharp and free of any oxide layer. An excellent correlation was found between particle sizes determined theoretically from magnetization versus field data and experimentally using STEM-Z which indicates the absence of any magnetically dead layers on the Ni nanoparticles within an experimental error of 0.1 monolayer.
Lysostaphin (1969)

Journal Article Lysostaphin Get access M. Glenn Koenig, M.D. M. Glenn Koenig, M.D. Vanderbilt University School of Medicine Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 119, Issue 1, January 1969, Pages 101–102, https://doi.org/10.1093/infdis/119.1.101 Published: 01 January 1969
Determination of natural killer cell function by flow cytometry (1996)

Natural killer cells (NK cells) are a subset of peripheral blood lymphocytes that mediate non-major histocompatibility complex-restricted cytotoxicity of foreign target cells. The "gold standard" assay for NK cell activity has been the chromium release assay. This method is not easily performed in the clinical laboratory because of difficulties with disposal of radioactive and hazardous materials, short reagent half-lives, expense, and difficulties with assay standardization. We describe a flow cytometric assay for the clinical measurement of NK cell activity. This study compared the chromium release assay and the flow cytometric assay by using clinically relevant specimens. There were no significant differences between the two assays in the measurement of lytic activity for 17 peripheral blood specimens or in reproducibility in repeated samplings of healthy individuals. We also established a normal range of values for NK activity in healthy adults and identified a small cluster of individuals who have exceptionally high or low levels of NK activity. The flow cytometric assay was validated by testing specimens from subjects expected to have abnormally low levels of NK activity (pregnant women) and specimens from healthy individuals in whom the activity of NK cells was enhanced by exposure to interleukin-2 or alpha interferon. Treatment with these agents was associated with a significant increase in NK activity. These results confirm and extend those of others, showing that the flow cytometric assay is a viable alternative to the chromium release assay for measuring NK cell activity.
Application of a Proposed Standard for Testing Soiling and Cleanability of Resilient Floor Coverings (2003)

Article Application of a Proposed Standard for Testing Soiling and Cleanability of Resilient Floor Coverings was published on November 1, 2003 in the journal Tenside Surfactants Detergents (volume 40, issue 6).
WU-Blast2 server at the European Bioinformatics Institute (2003)

Since 1995, the WU-BLAST programs (http://blast.wustl.edu) have provided a fast, flexible and reliable method for similarity searching of biological sequence databases. The software is in use at many locales and web sites. The European Bioinformatics Institute's WU-Blast2 (http://www.ebi.ac.uk/blast2/) server has been providing free access to these search services since 1997 and today supports many features that both enhance the usability and expand on the scope of the software.
Comparative mapping of the two wheat leaf rust resistance loci<i>Lr1</i>and<i>Lr10</i>in rice and barley (1998)

The wheat genome is large, hexaploid, and contains a high amount of repetitive sequences. In order to isolate agronomically important genes from wheat by map-based cloning, a simpler model of the genome must be used for identifying candidate genes. The objective of this study was to comparatively map the genomic regions of two wheat leaf rust disease resistance loci, Lr1 and Lr10, in the putative model genomes of rice and barley. Two probes cosegregating with the Lr1 gene on chromosome 5DL of wheat were studied. The rice sequences corresponding to the two probes were isolated and mapped. The two probes mapped to two different rice chromosomes, indicating that the organization of the region orthologous to Lr1 is different in rice and wheat. In contrast, synteny was conserved between wheat and barley in this chromosomal region. The Lrk10 gene cosegregated with Lr10 on chromosome 1AS in wheat. The rice gene corresponding to Lrk10 was mapped on rice chromosome 1, where it occurred in many copies. This region on rice chromosome 1 corresponds to the distal part of the group 3S chromosomes in Triticeae. The synteny is conserved between rice chromosome 1 and the Triticeae group 3S chromosomes up to the telomere of the chromosomes. On group 3S chromosomes, we found a gene that is partially homologous to Lrk10. We conclude that in the genomic regions studied, there is limited and only partially useful synteny between wheat and rice. Therefore, barley should also be considered as a model genome for isolating the Lr1 and Lr10 genes from wheat.
Pre-symptomatic diagnosis and treatment of filovirus diseases (2015)

Filoviruses are virulent human pathogens which cause severe illness with high case fatality rates and for which there are no available FDA-approved vaccines or therapeutics. Diagnostic tools including antibody- and molecular-based assays, mass spectrometry, and next-generation sequencing are continually under development. Assays using the polymerase chain reaction (PCR) have become the mainstay for the detection of filoviruses in outbreak settings. In many cases, real-time reverse transcriptase-PCR allows for the detection of filoviruses to be carried out with minimal manipulation and equipment and can provide results in less than 2 h. In cases of novel, highly diverse filoviruses, random-primed pyrosequencing approaches have proved useful. Ideally, diagnostic tests would allow for diagnosis of filovirus infection as early as possible after infection, either before symptoms begin, in the event of a known exposure or epidemiologic outbreak, or post-symptomatically. If tests could provide an early definitive diagnosis, then this information may be used to inform the choice of possible therapeutics. Several exciting new candidate therapeutics have been described recently; molecules that have therapeutic activity when administered to animal models of infection several days post-exposure, once signs of disease have begun. The latest data for candidate nucleoside analogs, small interfering RNA (siRNA) molecules, phosphorodiamidate (PMO) molecules, as well as antibody and blood-product therapeutics and therapeutic vaccines are discussed. For filovirus researchers and government agencies interested in making treatments available for a nation's defense as well as its general public, having the right diagnostic tools to identify filovirus infections, as well as a panel of available therapeutics for treatment when needed, is a high priority. Additional research in both areas is required for ultimate success, but significant progress is being made to reach these goals.
Effect of hierarchical porosity in Beta zeolites on the Beckmann rearrangement of oximes (2016)

Hierarchical Beta zeolites with different Si/Al molar ratios, synthesized by crystallization of silanized protozeolitic units, were investigated in the liquid-phase Beckmann rearrangement of cyclohexanone and cyclododecanone oximes.
Método del punto medio para el cálculo del pH: una metodología práctica y sencilla para los nuevos estudios de grado (2008)

El estudio del equilibrio acido-base constituye una parte importante de los contenidos de la asignatura de Quimica Analitica impartida en diferentes titulaciones universitarias. Uno de los objetivos basicos de este estudio es el aprendizaje del calculo del pH, que suele presentar una especial dificultad para los estudiantes. En general, estas carencias aparecen ya en los niveles de ensenanza no universitaria y continuan en el nivel universitario si no son adecuadamente corregidas. Ademas, en este ultimo caso el problema se agrava con aquellos estudiantes que no han alcanzado suficiente formacion matematica y quimica. El diseno de los nuevos grados universitarios preve mantener el estudio del equilibrio acido-base en distintos grados de ciencias. Por otro lado, se pretende que el fomento del auto-aprendizaje sea uno de los pilares basicos de los nuevos planes de estudio. Por este motivo, el desarrollo de metodologias sencillas que faciliten la resolucion de problemas complejos, tal como el calculo del pH, permitira facilitar su comprension y otorgar un mayor grado de autonomia al estudiante en la resolucion de problemas. En esta linea, se presenta un metodo sencillo para el calculo del pH, denominado metodo del punto medio, aplicable tanto a sistemas monoproticos como poliproticos con resultados satisfactorios. El metodo hace uso de un diagrama (segmento lineal) que delimita las regiones de pH donde predominan las distintas especies acido-base del sistema considerado. Para cada caso particular, se marcan dos puntos sobre el diagrama (los limites del segmento) de modo que el calculo del pH se reduce a determinar el punto central del mismo, previo cumplimiento de una serie de restricciones. El metodo permite calcular el pH de una disolucion en unos pocos segundos y es muy simple para ser utilizado por estudiantes con escasa preparacion matematica.
Distributed sensing using stimulated Brillouin scattering : towards ultimate resolution. (1997)

In this paper, we discuss the fundamental limitations of the SBS analysis as a distributed sensing method when the spatial resolution is in the meter range. We also present a novel experimental configuration that reaches the best performances achievable for this kind of sensors.
Algorithms for Optimal Energy Management in the Smart Grid (2015)

Smart grid (SG) is regarded as the next generation power grid, which implements an innovative idea for a highly automated and integrated power system. 
The two-way energy and information flows in the SG, together with the smart devices, bring new perspectives to energy management and demand response. Meanwhile, innovative grid components, such as microgrid (MG) and electric vehicle, are emerging as new applications which bring many benefits as well as more chanllegens in SG. 
Therefore, we explore possible solutions to these chanllegening but interesting problems.

In this dissertation, we first present an introduction of the SG, and the research involved in different areas of SG. We then investigate an online algorithm for energy distribution in a SG environment. The proposed online algorithm are quite general, suitable for a wide range of utility, cost and pricing functions. And it is asymptotically optimal without any future information.
Following this, we then propose a distributed online algorithm. Comparing to the previous one, it solves the online problem in a distributed manner and mitigates the user privacy issue by not sharing user utility functions.
Both algorithms are evaluated with trace-driven simulations and shown to outperform a benchmark scheme. 

We then propose a hierarchical power scheduling approach to optimally manage power trading, storage and distribution in a smart power grid with a Macrogrid and cooperative MGs. 
We develop online algorithms both for cooperative MGs and the Macrogrid. 
The proposed hierarchical power scheduling algorithms are evaluated with trace-driven simulations and are shown to outperform several existing schemes with considerable gains.

Also, we also introduce the simultaneous inference for power generation forecasting from renewable energy resources. We then apply it for solar intensity prediction using a real trace of weather data, where the performance is demonstrated over existing approaches.
Fuzzy logic power control of device to device communication underlay TD-LTE-A system (2013)

When the D2D communication technology is introduced into the cellular system, especially when the D2D UEs multiplex the non-orthogonal spectrum resources of cellular UEs, the transmit power of D2D UEs and cellular UEs must be strictly controlled to reduce the interference between two kinds of UEs and benefit from D2D communication mode. In this paper, the mathematical model of power control of D2D communication underlay LTE-A system is established, and the power control principles in this scenario are achieved. Based on the principles, a continuous fuzzy power control scheme for D2D communication UEs is designed to achieve better communication quality for D2D UEs, while the cellular UEs can communicate normally in low transmit power. The simulation results reveal that the continuous fuzzy power control scheme can improve the D2D UEs' average SINR and achieve lower LTE UEs' outage probability with more rapid convergence than fixed-step power control scheme.
Effect of the Covalent Bond on the Radiative Properties of the Ligand-Localized 3.pi..pi. State of Rhodium Complexes with benzo[h]quinoline (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffect of the Covalent Bond on the Radiative Properties of the Ligand-Localized 3.pi..pi. State of Rhodium Complexes with benzo[h]quinolineHisayuki Miki and Tohru AzumiCite this: J. Phys. Chem. 1994, 98, 24, 6059–6062Publication Date (Print):June 1, 1994Publication History Published online1 May 2002Published inissue 1 June 1994https://pubs.acs.org/doi/10.1021/j100075a003https://doi.org/10.1021/j100075a003research-articleACS PublicationsRequest reuse permissionsArticle Views55Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Mutational Analysis of the<i>ompA</i>Promoter from<i>Flavobacterium johnsoniae</i> (2007)

Sequences that mediate the initiation of transcription in Flavobacterium species are not well known. The majority of identified Flavobacterium promoter elements show homology to those of other members of the phylum Bacteroidetes, but not of proteobacteria, and they function poorly in Escherichia coli. In order to analyze the Flavobacterium promoter structure systematically, we investigated the -33 consensus element, -7 consensus element, and spacer length of the Flavobacterium ompA promoter by measuring the effects of site-directed mutations on promoter activity. The nonconserved sequences in the spacer region and in regions close to the consensus motifs were randomized in order to determine their importance for promoter activity. Most of the base substitutions in these regions caused large decreases in promoter activity. The optimal -33/-7 motifs (TTTG/TANNTTTG) were identical to Bacteroides fragilis sigma(ABfr) consensus -33/-7 promoter elements but lacked similarity to the E. coli sigma(70) promoter elements. The length of the spacer separating the -33 and -7 motifs of the ompA promoter also had a pronounced effect on promoter activity, with 19 bp being optimal. In addition to the consensus promoter elements and spacer length, the GC content of the core promoter sequences had a pronounced effect on Flavobacterium promoter activity. This information was used to conduct a scan of the Flavobacterium johnsoniae and B. fragilis genomes for putative promoters, resulting in 188 hits in B. fragilis and 109 hits in F. johnsoniae.