gebhart/patrepeval huggingface dataset:
Effects of eicosapentaenoic acids on oxidative stress and plasma fatty acid composition in patients with lupus nephritis. (2005)

Eicosapentaenoic acid (EPA) is one of the major components of fish oil, which was reported to have antiatherogenic, anti-inflammatory and immune suppressive effects. In the present study, highly purified EPA was administered to patients with lupus nephritis and the effects of EPA on urinary 8-isoprostane, a reliable marker of oxidative stress, were investigated in these patients. Six outpatients (1 man and 5 women), with lupus nephritis diagnosed by renal biopsy, were entered in the study. We administered 1800 mg EPA ethyl-ester (purity > 95%) daily and examined the urinary 8-isoprostane levels and plasma fatty acid composition before and 3 months after EPA treatment. The urinary 8-isoprostane levels were significantly decreased after the treatment compared with those before the treatment (from 530 +/- 113 pg/mg x Cr to 235 +/- 49 pg/mg x Cr, p = 0.02). The EPA levels in the plasma phospholipid (PL) fraction were significantly increased after the treatment (from 3.30 +/- 0.64 mol% to 8.01 +/- 0.47 mol%, p < 0.001). Arachidonic acid (AA) levels in the plasma PL fraction were significantly decreased after the treatment (from 9.47 +/- 0.28 mol% to 7.33 +/- 0.43 mol%, p < 0.001). The ratios of EPA to AA were significantly increased after the treatment (from 0.35 +/- 0.07 to 1.14 +/- 0.16, p < 0.001). Thus, this preliminary study indicated that EPA might exert beneficial effects on lupus nephritis by decreasing the oxidative stress.
A CMOS Imager with Focal Plane Compression (2006)

A focal plane video compression integrated circuit is presented. The design consists of a 128 times 128 pixel array and a bank of column-level processors. Each one of the column-level processors performs the tasks of image decorrelation, quantization, and entropy encoding. The chip provides at its output a compressed bit stream. The integration of the quantizer and the entropy encoder at the column level is possible by sharing circuitry between a single-slope analog-to-digital converter and a Golomb-Rice entropy encoder. In addition, the design includes a low-complexity algorithm for the adaptation of the Golomb-Rice coder to the statistics of the video signal. The design has been fully verified through simulations and has been implemented in a 0.35 mum CMOS technology. The chip layout occupies an area of 7 times 5 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup>
PHOTOREGULATION OF BIOLOGICAL ACTIVITY BY PHOTOCHROMIC REAGENTS, III. PHOTOREGULATION OF BIOELECTRICITY BY ACETYLCHOLINE RECEPTOR INHIBITORS (1969)

The photochromic compounds N-p-phenylazophenyl-N-phenylcarbamylcholine chloride and p-phenylazophenyltrimethylammonium chloride inhibit the carbamylcholine-produced depolarization of the excitable membrane of the monocellular electroplax preparation of Electrophorus. The trans isomer of each predominates in the light of a photoflood (420 mmu) lamp; they are stronger inhibitors than the cis isomers, which predominate under ultraviolet (320 mmu) irradiation. The potential difference across the excitable membrane may be photoregulated by exposing an electroplax in the presence of a solution of carbamylcholine and either of the two compounds to light of appropriate wavelengths, since light shifts the cis-trans equilibrium. The system may be considered as a model illustrating how one may link a cis-trans isomerization, the first step in the initiation of a visual impulse, with substantial changes (20-30 mv) in the potential difference across an excitable membrane.
Evaluation of highly accelerated real‐time cardiac cine MRI in tachycardia (2013)

Electrocardiogram (ECG)-gated breath-hold cine MRI is considered to be the gold standard test for the assessment of cardiac function. However, it may fail in patients with arrhythmia, impaired breath-hold capacity and poor ECG gating. Although ungated real-time cine MRI may mitigate these problems, commercially available real-time cine MRI pulse sequences using parallel imaging typically yield relatively poor spatiotemporal resolution because of their low image acquisition efficiency. As an extension of our previous work, the purpose of this study was to evaluate the diagnostic quality and accuracy of eight-fold-accelerated real-time cine MRI with compressed sensing (CS) for the quantification of cardiac function in tachycardia, where it is challenging for real-time cine MRI to provide sufficient spatiotemporal resolution. We evaluated the performances of eight-fold-accelerated cine MRI with CS, three-fold-accelerated real-time cine MRI with temporal generalized autocalibrating partially parallel acquisitions (TGRAPPA) and ECG-gated breath-hold cine MRI in 21 large animals with tachycardia (mean heart rate, 104 beats per minute) at 3T. For each cine MRI method, two expert readers evaluated the diagnostic quality in four categories (image quality, temporal fidelity of wall motion, artifacts and apparent noise) using a Likert scale (1-5, worst to best). One reader evaluated the left ventricular functional parameters. The diagnostic quality scores were significantly different between the three cine pulse sequences, except for the artifact level between CS and TGRAPPA real-time cine MRI. Both ECG-gated breath-hold cine MRI and eight-fold accelerated real-time cine MRI yielded all four scores of ≥ 3.0 (acceptable), whereas three-fold-accelerated real-time cine MRI yielded all scores below 3.0, except for artifact (3.0). The left ventricular ejection fraction (LVEF) measurements agreed better between ECG-gated cine MRI and eight-fold-accelerated real-time cine MRI (mean difference, -1.6%) than between ECG-gated cine MRI and three-fold-accelerated real-time cine MRI (mean difference, -5.7%). Eight-fold-accelerated real-time cine MRI with CS yields acceptable diagnostic quality and relatively accurate LVEF measurements in the challenging setting of tachycardia.
Estradiol metabolism: an endocrine biomarker for modulation of human mammary carcinogenesis. (1997)

The natural estrogen 17beta-estradiol (E2) has a profound influence on proliferation and neoplastic transformation of mammary epithelium. The role of cellular metabolism of E2 in mammary carcinogenesis, however, remains to be elucidated. Explant culture and cell culture models developed from noncancerous human mammary tissue were used to examine modulation of E2 metabolism in response to treatment with prototype rodent mammary carcinogens and the ability of the naturally occurring phytochemical indole-3-carbinol (13C) to influence E2 metabolism and regulate aberrant proliferation. In the two models, treatment with the chemical carcinogens 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene altered the metabolism of E2 as determined from the radiometric (tritium release) and gas chromatography-mass spectrometry (GC-MS) assays. This alteration in E2 metabolism was accompanied by aberrant proliferation and abrogation of apoptosis as determined by the extent of replicative DNA synthesis, S-phase fraction and Sub G0 (apoptotic) peak. Exposure of carcinogen-initiated cultures to 13C resulted in induction of C2-hydroxylation of E2 and of apoptosis and downregulation of hyperproliferation. Determination of altered cellular metabolism of E2 in response to initiators and modulators of carcinogenesis and evaluation of cell cycle related markers for proliferation and apoptosis may provide a mechanism-oriented approach to validate E2 metabolism as an endocrine biomarker for induction and prevention of human mammary carcinogenesis.
Load Balanced Parallel Simulation of Particle-Fluid DEM-SPH Systems with Moving Boundaries. (2007)

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A two-channel adaptive filtering approach for recognition of the QRS morphology (2002)

An approach for QRS morphology classification is proposed. The cross-correlation structure between two electrocardiogram (ECG) channels is used to characterize different QRS morphologies. The classifier consists of a bank of adaptive filters, one for each QRS morphology; each filter has the QRS samples sequence of an ECG channel as reference input, and attempts to predict the QRS samples sequence of the other channel. A cumulative error and a prefixed threshold are used to decide the class assignment or a new class generation. The classifier was tested on the MIT-BIH database, showing satisfying sensitivity and positive predictive accuracy values. The method can be used to add useful information and to improve the performance of a template matching classifier.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Non‐invasive cryolipolysis for body contouring in Chinese—a first commercial experience (2012)

Non-invasive cryolipolysis is effective for body contouring in Chinese. It is shown to have a further improvement with subsequent treatment sessions but of a lesser extent. The second treatment was statistically significant for abdomen, though not for love handles.
1,4 Addition of acyl groups to conjugated enones (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT1,4 Addition of acyl groups to conjugated enonesElias J. Corey and L. S. HegedusCite this: J. Am. Chem. Soc. 1969, 91, 17, 4926–4928Publication Date (Print):August 1, 1969Publication History Published online1 May 2002Published inissue 1 August 1969https://pubs.acs.org/doi/10.1021/ja01045a061https://doi.org/10.1021/ja01045a061research-articleACS PublicationsRequest reuse permissionsArticle Views555Altmetric-Citations89LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
From natural language requirements to UML class diagrams (2015)

Unified Modeling Language (UML) is the most popular modeling language for analysis, design and development of the software system. There has been a lot of research interest in generating these UML models, especially class diagrams, automatically from Natural Language requirements. The interest in class diagrams can be attributed to the fact that classes represent the abstractions present in the system to be developed. However, automated generation of UML class diagrams is a challenging task as it involves lot of pre-processing or manual intervention at times. In this paper, we present dependency analysis based approach to derive UML class diagrams automatically from Natural Language requirements. We transform the requirements statements to an intermediary frame-based structured representation using dependency analysis of requirements statements and the Grammatical Knowledge Patterns. The knowledge stored in the frame-based structured representation is used to derive class diagrams using rule-based algorithm. Our approach has generated similar class diagrams as reported in earlier works based on linguistic analysis with either annotation or manual intervention. We present the effectiveness of our approach in terms of recall and precision for the case-studies presented in earlier works.
Coupled Well and Reservoir Simulation Models to Optimize Completion Design and Operations for Subsurface Control (2008)

Abstract Ensuring long-term optimum completion performance is important for the economic development of any field. As fields are now developed with fewer wells and in more technically challenging environment, new technologies are required to provide guidance and quantify the impact of completion design. This paper presents a new methodology in coupling ExxonMobil's reservoir simulator and a detailed well hydraulics simulator that simulates reservoir, wellbore tubing and wellbore annulus flow simultaneously. Case studies indicate that unique completions opportunities in optimizing completions options, especially inflow control devices, are captured by using the modeling capabilities Completion strategies frequently include provisions to 1) maintain a uniform production profile along the wellbore, 2) manage future risks (early water or gas breakthrough) and mitigate the potential for sand production, and 3) improve reservoir recovery. Completion options include open hole, cased hole, inflow regulation devices (inflow/flow control devices and inflow valves), sand screens, or pre-drilled liners. Different from nodal based wellbore simulation in a conventional reservoir simulator, the proposed coupled well and reservoir simulation provides not only detailed information on the tubing and annulus flow and associated pressure drops in and throughout all completion types, but also the impact of completions on short and long term reservoir flow and recovery. Studies have shown the importance in utilizing the coupled model in both history matching and model prediction when advanced completions are applied. The significance of this new coupled approach is its ability to capture both flow dynamics through various completion options and reservoir performance
Mass transport in thin supported silica membranes (2000)

In this thesis multi-component mass transport in thin supported amorphous silica membranes is discussed. These membranes are micro-porous, with pore diameters smaller than 4Å and show high fluxes for small molecules (such as hydrogen) combined with high selectivities for these molecules with respect to larger ones. The chemical and thermal stability of silica membranes are favourable compared to those of organic membranes. These properties make silica membranes interesting candidates for separation of permanent gases in chemically and thermally aggressive environments. The field of membrane science is briefly introduced, with emphasis on the relevance of inorganic membranes for the chemical process industry. Several aspects of supported amorphous micro-porous silica layers are discussed, followed by the project objectives and thesis outline.
Clinical use of contrast media in magnetic resonance imaging. (1990)

Two types of contrast media are now used in clinical magnetic resonance imaging (MRI). Intravenous gadolinium-DTPA serves as a marker of blood-brain barrier disruption while intravenous magnetic iron oxide particles are of value in imaging the liver and spleen. The efficacy of MRI is improved with these agents but the examination is prolonged.
20.6 A 0.5V-V<inf>IN</inf> 1.44mA-class event-driven digital LDO with a fully integrated 100pF output capacitor (2017)

In today's system-on-chip designs, a low-drop-out voltage regulator (LDO) is one of the most popular choices to create a distinct voltage domain owing to its high power density. Many LDOs, however, need a large output capacitor (C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">OUT</sub> ) to compensate a fast load current (I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">LOAD</sub> ) change, increasing the number of pins and off-chip components. In synchronous digital LDO designs, high frequency can miniaturize C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">OUT</sub> , but it inevitably causes power inefficiency [2]. A recent work has instead employed an event-driven (ED) control scheme to alleviate the C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">OUT</sub> requirement, demonstrating a 400μA-class digital LDO with a C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">OUT</sub> of 400pF [1]. The ED scheme is promising, but it is still desirable to develop an LDO which can support a larger I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">LOAD</sub> with a smaller C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">OUT</sub> . This is indeed a daunting challenge since a substantial reduction in feedback latency (T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">LAT</sub> ) is necessary to retain the same level of output voltage change (ΔV <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">OUT</sub> ) with a smaller C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">OUT</sub> . In this work, to shorten latency, we propose to infuse fine-grained parallelism into ED control systems and develop a fully integrated digital LDO. The prototyped LDO can support 1.44mA I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">LOAD</sub> at 0.5V V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">IN</sub> , 0.45V V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">SP</sub> , and 99.2% peak current efficiency. The LDO shows less than 34mV (7.6%) ΔV <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">OUT</sub> with a 0.1nF C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">OUT</sub> when ΔI <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">LOAD</sub> is ±1.44mA.
Survey on depth perception in head mounted displays: distance estimation in virtual reality, augmented reality, and mixed reality (2019)

Depth perception is one of the important elements in virtual reality (VR). The perceived depth is influenced by the head mounted displays that inevitability decreases the virtual content's depth perception. While several questions within this area are still under research; the main objective of this study is to survey the recently conducted studies on depth perception in VR, augmented reality (AR), and mixed reality (MR). First, depth perception in the human visual system is discussed including the different visual cues involved in depth perception. Second, research performed to understand and confirm depth perception issue is examined. The contributions made to improve depth perception and specifically distance perception will be discussed with their main proposed design key, advantages, and limitations. Most of the contributions were based on using one or two depth cues to improve depth perception in VR, AR, and MR.
Comparison of Uptake of Multiple Clinical Radiotracers into Brown Adipose Tissue Under Cold-Stimulated and Nonstimulated Conditions (2007)

BAT uptake of (18)F- or (3)H-FDG, (123)I-MIBG, and (3)H-l-methionine was significantly increased over the control state by exposure to cold. Increased uptake of (201)TlCl relative to blood in cold-stimulated BAT suggests that blood flow in BAT is increased by exposure to cold. The greater increased uptake with (18)F- or (3)H-FDG, (123)I-MIBG, and (3)H-l-methionine, and the immunohistostaining findings, suggest that other factors in addition to blood flow (e.g., increased metabolism, increased transport, or metabolic trapping of the tracers) are involved in cold-stimulated BAT activation. Knowledge that high uptake in BAT may possibly be observed on clinical scans using several radiotracers, especially after patients are exposed to the cold, may lead to more accurate interpretation of clinical studies.
Residencia Palace (1963)

Se disponen 35 apartamentos—cuyas superficies varían entre las seis plantas; los del ático, se desarrollan en dos niveles. Todos ellos presentan la zona de estar y el dormitorio principal orientados al sur; solamente los ambientes secundarios miran al norte. Las unidades más pequeñas están alineadas a lo largo de un corredor, e iluminan y ventilan directamente los correspondientes servicios, aprovechando la diferencia de altura de techo del mismo. Los apartamentos están distribuidos en dos alas, independientemente servidas por escaleras y ascensores; en la planta baja hay un restaurante con una amplia terraza. Se ha logrado, plenamente, aligerar el aspecto exterior del notable volumen del edificio, fraccionando las fachadas, mediante diversas características arquitectónicas—celosías, pilastras, terrazas voladas, etcétera—. Con ello se ha conseguido, por una parte, que el edificio no pese y sea soportado por el ambiente paisajista que lo rodea; y por otra, que los propietarios de los apartamentos, aun funcionando en régimen de copropiedad—para sus vacaciones en la montaña—no se sientan ocupantes de células, como en las casas de la ciudad.
Plasma-Assisted Removal of NO from Gas Streams via Ammonia Injection (1997)

Removal of nitric oxide (NO) from gas streams via combined NH3 injection with dielectric barrier discharge (DBD) plasmas was experimentally investigated. Removal of NO was principally achieved via its reaction with NHi radicals generated with DBD plasmas. Removal efficiency of NO was measured as a function of stoichiometric ratio, applied voltage, and inlet NO concentration of the gas stream. Experimental results showed that as much as 80% of NO was removed from gas streams operating at room temperature. Increase in NH3/NO molar ratio and applied voltage enhances NO removal efficiency. NO removal efficiency decreases slightly as oxygen content in the gas stream increases from 0% to 6%, indicating the characteristic of selective reduction in this process. However, 15 ppmv N2O was detected with Fourier transform infrared for gas streams containing 6% by volume O2 and 300 ppmv NO. Results of this study indicated that conventional SNCR process could be operated at a much lower temperature by applying plasma technology to generate NHi radicals. Key words: Plasma; dielectric barrier discharge; NOx removal; selective reduction; NH3 injection