gebhart/patrepeval huggingface dataset:
Deep Neural Networks Optimization Based On Deconvolutional Networks (2018)

Feature extraction is the most important part of the whole object recognition and target detection system. Convolutional Networks have evolved to the state-of-the-art technique for computer vision tasks owing to the predominant feature extraction capability. However, the working process of Convolutional Networks is invisible, which makes it difficult to optimize the model. To evaluate a Convolutional Network, we introduce a novel way to project the activities back to the input pixel space, revealing what input pattern originally caused a specific activation in the feature maps. Using this visualization technique, we take the feature extraction of sunflower seed image containing an impurity as an example, and attempt to change the architecture of traditional Convolutional Networks in order to extract better specific features for target images. After a series of improvements, we got a new Convolutional Network which is more conducive to the target images feature extraction and the number of parameters is less than before, which is conducive to the transplantation of the small system. Our model can be docking the state-of-the-art recognition networks according to different application scenarios, so as to structure a complete automatic recognition system.
Robust Real-Time Registration of RGB-D Images using Multi-Resolution Surfel Representations (2012)

Fast and robust registration of 3D scans is required in many approaches to perception in robotics such as pose tracking or simultaneous localization and mapping. We propose a novel efficient method to register RGB-D images. We convert the image content into a multi-resolution surfel representation and exploit the dense image neighborhood to construct such views at high frame-rates on a single CPU. Our approach registers views using an efficient and robust variant of the Iterative Closest Points algorithm. We evaluate our method on a recently published benchmark dataset and achieve results beyond the state-of-the-art. We also report on the successful public demonstration of our method at RoboCup 2011. 1
10.7 MHz bandpass delta-sigma A/D modulators (2002)

Two second-order bandpass delta-sigma A/D modulators have been implemented in a 0.8 /spl mu/m BiCMOS process to demonstrate the feasibility of converting a 10.7 MHz radio IF signal to digital form. The circuits, based on switched-C biquads, are clocked at 42.8 MHz and demonstrated 55 dB SNR in a 200 KHz bandwidth while dissipating 60 mW of power from a 5 V supply.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Study on the Cardiopulmonary Resuscitation Methods in Ambulance (2014)

이 연구는 소방에 근무하는 응급구조사에 의해 시행되는 구급차 내 심폐소생술 방법에 관한 연구이다. 연구 대상은 경기도 관할 780명으로 2012년 보수교육 종료 후 설문을 통하여 수집하였다. 일반적 특성, 가슴압박 방법(한 손 가슴압박 VS 두 손 가슴압박), 심폐소생술 방법(표준심폐소생술 VS 가슴압박소생술) 등에 대하여 Chi-square test, t-test. ANOVA로 분석하였다. 한 손을 이용한 가슴압박 14.0%, 두 손을 이용한 가슴압박 86.0%를 보였고, 표준심폐소생술(가슴압박 VS 인공호흡)은 28.3%, 가슴압박소생술 71.7%를 보였다. 고품질의 심폐소생술을 위해서는 심정지 환자의 구급 출동만이라도 운전자 포함 3명 이상의 응급구조사가 출동할 수 있도록 탄력적인 인력 운영 방안이 필요하며, 역량 강화를 위한 심폐소생술의 정기적인 교육이 필요하다. The purpose of this study is to investigate the CPR within ambulance. The Subjects were 890 emergency medical technicians in fire department in Gyeonggido. After continuing education program, the emergency medical technicians completed the questionnaires from January to February, 2012. Questionnaire consisted of demographic characteristics, method of chest compression (one handed or two handed), chest compression - ventilation ratio, and hands only CPR. Data were analyzed by frequency analysis and Chi-square test, t-test. One-way analysis of variance (ANOVA) was followed by Scheffe post-hoc test to analyze changes in all parameters between all groups. One handed chest compression accounted for 14.0% and two handed chest compression accounted for 86.0%. Hands only CPR accounted for 71.7% and standard CPR (30:2) accounted for 28.3%. In order to perform the high quality CPR, as least three persons must be dispatched in the ambulance. The flexible management of manpower may improve the survival from the cardiac arrest. A systemic approach for educating and training EMT's in CPR is needed.
SPECTROPHOTOMETRIC STUDIES XII. OBSERVATION OF CIRCULATING BLOOD IN VIVO, AND THE DIRECT DETERMINATION OF THE SATURATION OF HEMOGLOBIN IN ARTERIAL BLOOD (1945)

The ocular sequelae of EVD can lead to vision impairment or blindness, if untreated. Keys to the prevention of such an outcome include timely evaluation and access to appropriate ophthalmic care. The persistence of EBOV in the eye and other immune-privileged sites is the subject of ongoing investigation, but should not be a barrier to care if appropriate screening and biosafety measures are taken. Improved understanding of the pathogenesis of this condition and ongoing clinical care are needed for EVD survivors at-risk for ocular complications.
Automated Extraction of Genomic DNA from Medically Important Yeast Species and Filamentous Fungi by Using the MagNA Pure LC System (2002)

A fully automated assay was established for the extraction of DNA from clinically important fungi by using the MagNA Pure LC instrument. The test was evaluated by DNA isolation from 23 species of yeast and filamentous fungi and by extractions (n = 28) of serially diluted Aspergillus fumigatus conidia (10(5) to 0 CFU/ml). Additionally, DNA from 67 clinical specimens was extracted and compared to the manual protocol. The detection limit of the MagNA Pure LC assay of 10 CFU corresponded to the sensitivity when DNA was extracted manually; in 9 of 28 runs, we could achieve a higher sensitivity of 1 CFU/ml blood, which was found to be significant (p <or= 0.004). DNA from all fungal species analyzed could be extracted and amplified by real-time PCR. Negative controls from all MagNA Pure isolations remained negative. Sixty-three clinical samples showed identical results by both methods, whereas in 4 of 67 samples, discordant results were obtained. Thus, the MagNA Pure LC technique offers a fast protocol for automated DNA isolation from numerous fungi, revealing high sensitivity and purity.
Prevalence of Hard Ticks Infesting Cattle and the Associated Risk Factors: A Study Conducted in Ethiopia (2020)

Background: Ticks are widely distributed throughout the world particularly in tropical and sub-tropical countries, which cause tremendous economic importance in livestock production. This cross-sectional study was conducted to estimate the prevalence, determine the identity of ixodid ticks at the genus level, and their preferred sites on body parts of cattle at Itang special district of Ethiopia. Despite the fact that numerous studies were conducted on ixodid ticks of cattle in many parts of Ethiopia, no enough data is available on ticks infecting cattle at the study area. Data on the prevalence, type of ticks, and specific predilection site determination is essential for the development of an effective control strategy of ticks and tick-borne diseases. Result: From the total of 384 cattle examined for ixodid ticks, 320 (83.3%) of the animals were found positive for one or more types ticks. A total number of 2000 adult ticks were collected from half body parts of infested cattle and identified at the genus level. From the infested cattle, 3 genera namely Amblyomma, Hyalomma, and Rhipiciphalus and one subgenus Boophilus were identified with a relative infestation rate of 32.8%, 19.1%, 12.7%, and 35.5% respectively. The higher average sex ratio of 2.55:1 was observed in males than females in all genera of studied ticks. The study also found that the most infested body parts of the cattle were dewlap/brisket (20.1%) followed by genital and anal (19.7%), neck and head (19.4%), udder and scrotum (17.5%), belly (17.1%), and legs (6.2%). Age-wise ticks infestation was recorded higher in 5 years old and above at 85.5% than in younger cattle (<5 years old) at 79.6%. The infestation level of ticks in poor, medium and good body condition was found to be 86.7%, 90.9%, and 75.3% respectively. Conclusion: The study revealed the widespread occurrence of ixodid tick infestation in cattle of the study area. Thus improved management practices and well-coordinated control interventions are required and further study at specieslevel identification and their zoonotic importance are recommended.
Doubly-chained tree data base organisation--analysis and design strategies (1977)

Doubly-chained tree data base (file) structures are analysed and modelled, taking into account realistic implementation-oriented factors. Formulations for average access time and storage requirements are derived, showing the effect on performance and the interrelation of the characteristics of the contents of the data base, the complexity of the queries, storage device characteristics and processing times, and implementation-oriented (e.g. storage mapping) alternatives. Performance results are obtained from these models for six real life data bases. The doubly-chained alternatives are compared and evaluated to provide practical design guidelines and strategies.
Auto-embossed Bragg gratings from self-organizing polymers: chemical tuning of periodicity and photoinduced anisotropy (1996)

Self-organizing cellulosic polymers are used to explore implications of intrinsic structural anisotropy on light propagation and on Bragg grating replication in thin film waveguides. Polarized waveguide Raman spectroscopy indicates that cellulose acetate and regenerated cellulose polymers show 2D isotropy in the plane of the film. These measurements require that polarization artifacts be carefully separated to recover faithful spectral representations of massive structural order. Parasitic contributions to polarization dependent Raman data are enumerated. Holographic surface relief gratings can be replicated by partially ordered cellulose acetate. Base hydrolysis of the pyranose ester substituents liberates hydroxycellulose (native cellulose) that is largely amorphous, but retains the bulk structural anisotropy of the esterified parent polymer. The latent image of the grating device is passed from the cellulose acetate to the next generation hydroxycellulose film. This process is called `autoembossing', and self-replicates a functional grating device whose period can be effectively doubled. Anisotropy can also be induced with polarized light in hybrid organic/inorganic glass (organosilicate) waveguides prepared by sol-gel polycondensation. We describe novel photopoling experiments that `write' refractive index variations in thin organosilicate films. These written features can be read by a form of autoscopic polarized Raman scattering, and in some cases `erased' by a guided, polarized laser beam. To our knowledge this is the first example of photo-induced anisotropy in hybrid sol-gel glass waveguides that is unrelated to bond isomerization commonly associated with photo-poling in dye-doped polymers or glasses.
Effect of cimetidine on the pharmacokinetics of the metabolites of metamizol. (1997)

Metamizol (dipyrone) is hydrolyzed in the gastrointestinal tract to the pharmacologically active metabolite 4-methyl-amino-antipyrine (4-MAA), which is transformed by both, oxidation to 4-formyl-amino-antipyrine (4-FAA) and demethylation to 4-amino-antipyrine (4-AA). 4-AA is acetylated to 4-acetyl-amino-antipyrine (4-AcAA). The aim of the present study was to investigate whether cimetidine will alter the pharmacokinetics of the metabolites of metamizol due to cimetidine-induced inhibition of the metabolic transformation of 4-MAA. The study was carried out in 12 patients with duodenal ulcer treated with cimetidine 1,000 mg daily over 20 days. A single oral dose of metamizol 1,500 mg was administered 2 days prior to commencement of cimetidine therapy to all patients. Two further doses of 750 and 1,500 mg of metamizol were given in a randomized order on days 8 and 13 during cimetidine treatment. Blood samples for determination of metamizol metabolites were drown over 48 hours post dose. Drug assays for metamizol metabolites and cimetidine were performed using HPLC methods. The patients were phenotyped for CYP2D6 and acetylation polymorphism. The results revealed that cimetidine interacted with 4-MAA by increasing the systemic availability, prolonging the elimination half-life and decreasing the systemic clearance of 4-MAA, whereas the renal clearances of 4-MAA remained unchanged. Consistent with cimetidine-induced changes in the oxidation of 4-MAA to 4-FAA, as well as in the demethylation of 4-MAA to 4-AA, were the decreased rates of production and the lower maximum concentrations of 4-FAA and 4-AA when metamizol was administered during cimetidine treatment (p < 0.05). No correlation was found between the decrease in the production rates of 4-FAA induced by cimetidine and the hydroxylation abilities of the patients, this suggesting that CYP2D6 is not involved in the metabolism of 4-MAA to 4-FAA. The acetylation of 4-AA to 4-AcAA was not affected by cimetidine. Cimetidine produced an increase not proportional to the dose in the systemic availability only of 4-MAA, whereas the kinetics of the other metabolites changed proportionally to the increasing dose of metamizol.
Experiments on the Release of CMOS-Micromachined Metal Layers (2010)

We present experimental results on the release of MEMS devices manufactured using the standard CMOS interconnection metal layers as structural elements and the insulating silicon dioxide as sacrificial layers. Experiments compare the release results of four different etching agents in a CMOS technology (hydrofluoric acid, ammonium fluoride, a mixture of acetic acid and ammonium fluoride, and hydrogen fluoride), describe various phenomena found during the etching process, and show the release results of multilayer structures.
Cyclic AMP-regulated synthesis of the tissue inhibitors of metalloproteinases suppresses the invasive potential of the human fibrosarcoma cell line HT1080. (1995)

Tissue inhibitors of metalloproteinases (TIMPs) play an important role in regulating the activity of matrix metalloproteinases (MMPs). Tumor cell invasion and metastasis closely correlate with the activities of two members of MMPs, MMP2 and MMP9, both of which degrade type IV collagen in basement membranes. We herein report that the treatment of HT1080 cells with 8-bromo-cAMP and other chemicals that activate cyclic adenylase activity induces the expression of TIMP1 and TIMP2 both at the mRNA and the protein levels and that this induction of TIMPs correlates with suppression of invasive phenotypes of HT1080 cells. Treatment with various cAMP-elevating reagents induced the expression of TIMPs and MMP2 in HT1080 cells, whereas the expression of MMP9 was not significantly affected. The protein amounts of TIMP1, TIMP2, and MMP2 secreted into the medium from HT1080 cells treated with 1 mM 8-bromo-cAMP were 7.9-, 9.3-, and 8.5-fold higher than those secreted from untreated cells, respectively. Induction of these mRNAs by 8-bromo-cAMP was blocked by HA1004, a protein kinase A inhibitor, but not by calphostin C, a protein kinase C inhibitor. Cycloheximide abolished the induction of TIMPs and MMP2 mRNAs by 8-bromo-cAMP, indicating that the induction depends on a newly synthesized protein(s) whose expression may be regulated by cAMP. Type IV collagenolytic activity and the invasiveness of HT1080 cells, both of which were suppressed by 8-bromo-cAMP, were efficiently restored when the cells were exposed to anti-TIMP antibodies, demonstrating the importance of the increased levels of TIMP1 and TIMP2 proteins for the cAMP-mediated suppression of both type IV collagenolytic activity and the invasiveness of HT1080 cells.
Multi-loops phase locked system (2003)

This paper describes the design of a system used to derive high-speed time signals for SONET/SDH based equipment. This system was combined of three phase-locked loops. After optimized separately, the parameters of the loops were combined together. These three phase-locked loops share the same filter and voltage-controlled oscillator, so the size of the chip is reduced.
Measurement of average decoding rates of the 61 sense codons in vivo (2014)

Most amino acids can be encoded by several synonymous codons, which are used at unequal frequencies. The significance of unequal codon usage remains unclear. One hypothesis is that frequent codons are translated relatively rapidly. However, there is little direct, in vivo, evidence regarding codon-specific translation rates. In this study, we generate high-coverage data using ribosome profiling in yeast, analyze using a novel algorithm, and deduce events at the A- and P-sites of the ribosome. Different codons are decoded at different rates in the A-site. In general, frequent codons are decoded more quickly than rare codons, and AT-rich codons are decoded more quickly than GC-rich codons. At the P-site, proline is slow in forming peptide bonds. We also apply our algorithm to short footprints from a different conformation of the ribosome and find strong amino acid-specific (not codon-specific) effects that may reflect interactions with the exit tunnel of the ribosome.
Printed Wiring Design Aspects of Using Permanent Photopolymer (Dry Film Solder Mask) Coatings (1979)

The advantages of incorporating permanent photopolymer (dry film solder mask) coatings into high density printed wiring designs to obtain maximum component density and high reliability are discussed. Although originally developed for use as solder masks, these materials offer significant advantages to the PCB designer. Specific items to be discussed include high density conductor routing, in accordance with the proposed MIL STD 275D, on the solder side and under closely spaced components, component and heat sink mounting, the use of permanent polymer coatings to avoid metallic growth problems, new industry and military specifications and standards that relate to the incorporation of photopolymer masks into PCB designs and effects of coatings on high density, controlled impedance transmission lines.
Glucosylceramide Synthases, a Gene Family Responsible for the Biosynthesis of Glucosphingolipids in Animals, Plants, and Fungi (2001)

Glucosylceramides are membrane lipids in most eukaryotic organisms and in a few bacteria. The physiological functions of these glycolipids have only been documented in mammalian cells, whereas very little information is available of their roles in plants, fungi, and bacteria. In an attempt to establish appropriate experimental systems to study glucosylceramide functions in these organisms, we performed a systematic functional analysis of a glycosyltransferase gene family with members of animal, plant, fungal, and bacterial origin. Deletion of such putative glycosyltransferase genes in Candida albicans and Pichia pastoris resulted in the complete loss of glucosylceramides. When the corresponding knock-out strains were used as host cells for homologous or heterologous expression of candidate glycosyltransferase genes, five novel glucosylceramide synthase (UDP-glucose:ceramide glucosyltransferase) genes were identified from the plant Gossypium arboreum (cotton), the nematode Caenorhabditis elegans, and the fungi Magnaporthe grisea, Candida albicans, and P. pastoris. The glycosyltransferase gene expressions led to the biosynthesis of different molecular species of glucosylceramides that contained either C18 or very long chain fatty acids. The latter are usually channeled exclusively into inositol-containing sphingolipids known from Saccharomyces cerevisiae and other yeasts. Implications for the biosynthesis, transport, and function of sphingolipids will be discussed.
Improvements in linear transform based speaker adaptation (2002)

Presents three forms of linear transform based speaker adaptation that can give better performance than standard maximum likelihood linear regression (MLLR) adaptation. For unsupervised adaptation, a lattice-based technique is introduced which is compared to MLLR using confidence scores. For supervised adaptation, estimation of the adaptation matrices using the maximum mutual information criterion is discussed which leads to the MMILR approach. Recognition experiments show that lattice MLLR can reduce word error rates on a Switchboard task by 1.4% absolute. For recognition of non-native speech from the Wall Street Journal database, a reduction in word error rate of 10-16% relative was obtained using MMILR compared to standard MLLR.
Caspase-1–Processed Cytokines IL-1β and IL-18 Promote IL-17 Production by γδ and CD4 T Cells That Mediate Autoimmunity (2011)

IL-1β plays a critical role in promoting IL-17 production by γδ and CD4 T cells. However, IL-1-targeted drugs, although effective against autoinflammatory diseases, are less effective against autoimmune diseases. Conversely, gain-of-function mutations in the NLRP3 inflammasome complex are associated with enhanced IL-1β and IL-18 production and Th17 responses. In this study, we examined the role of caspase-1-processed cytokines in IL-17 production and in induction of experimental autoimmune encephalomyelitis (EAE). Killed Mycobacterium tuberculosis, the immunostimulatory component in CFA used for inducing EAE, stimulated IL-1β and IL-18 production by dendritic cells through activation of the inflammasome complex and caspase-1. Dendritic cells stimulated with M. tuberculosis and myelin oligodendrocyte glycoprotein promoted IL-17 production by T cells and induced EAE following transfer to naive mice, and this was suppressed by a caspase-1 inhibitor and reversed by administration of IL-1β or IL-18. Direct injection of the caspase-1 inhibitor suppressed IL-17 production by CD4 T cells and γδ T cells in vivo and attenuated the clinical signs of EAE. γδ T cells expressed high levels of IL-18R and the combination of IL-18 and IL-23, as with IL-1β and IL-23, stimulated IL-17 production by γδ T cells, but also from CD4 T cells, in the absence of TCR engagement. Our findings demonstrate that caspase-1-processed cytokines IL-1β and IL-18 not only promote autoimmunity by stimulating innate IL-17 production by T cells but also reveal redundancy in the functions of IL-1β and IL-18, suggesting that caspase-1 or the inflammasome may be an important drug target for autoimmune diseases.
Can animal data predict human outcome? Problems and pitfalls of translational animal research (2012)

ISSN:1619-7070