gebhart/patrepeval huggingface dataset:
The DN30 Package for the Transport of Enriched Reprocessed Uranium - 11111 (2011)

In the last few years the volume of reprocessed enriched Uranium (RepU) transportation increased considerably and became an important issue. While the transport of enriched commercial grade Uranium in the form of Uranium Hexafluoride (UF6) is standard practice since decades the transport of RepU presents new challenges.
Myeloma ascites?a favorable outcome with cyclophosphamide therapy (1999)

A 71-year-old woman with multiple myeloma (MM) in remission was admitted for evaluation of recent abdominal distension and was diagnosed as having massive myeloma ascites. The fluid was characterized by a total nucleated cell count of 6,600/mm3 (67% plasma cells), with a plasma cell CD38+ phenotype. Chemical analysis of the fluid showed lactate dehydrogenase of 122 IU/L, total protein of 2.9 g/dL, albumin of 2.4 g/dL, diastase of 38 IU/dL, cholesterol of 46 mg/dL, and C-reactive protein of 3 g/dL. The serum-ascites albumin gradient (SAAG) was low (0.9). Electrophoresis of the ascitic fluid showed a monoclonal spike in the gamma region and immunoelectrophoresis confirmed the presence of lambda light chains similar to those seen in the urine. Further analysis of the ascitic fluid showed markedly elevated levels of beta2 microglobulin (11,161 microg/L) and interleukin-6 (146 pg/ml compared to serum level of 4.3 pg/ml). There was evidence of intraabdominal masses that completely resolved with continuous high-dose cyclophosphamide (750 mg/m2/day for four days) followed by clinical improvement and disappearance of the ascites. We stress the value of complete fluid characterization and intensive chemotherapy to achieve a favorable outcome.
Metric based node synchronization of the Viterbi decoder (2002)

Convolutional codes are used in digital communication systems to correct errors that occur during transmission. Before the decoder can correctly decode the received continuous bit sequence however, it must establish where codewords begin and end in this sequence. The process of determining codeword boundaries is called node synchronization. In this paper we develop a node synchronization algorithm based on metric difference values with the objectives of simple implementation and reliable performance. We consider the constraint length 7, rate 1/2 convolutional code standardized by the European Space Agency. We develop analytical results for the up/down counter framing algorithm, and through simulation investigate correlation in the sequence of metric values. Recommendations for framing parameters are based on both the analytical results and the response of the framing algorithm to correlated metric values. Simulations confirm that this simple approach results in reliable node synchronization.
Multi-species biofilms defined from drinking water microorganisms provide increased protection against chlorine disinfection (2013)

A model biofilm, formed of multiple species from environmental drinking water, including opportunistic pathogens, was created to explore the tolerance of multi-species biofilms to chlorine levels typical of water-distribution systems. All species, when grown planktonically, were killed by concentrations of chlorine within the World Health Organization guidelines (0.2-5.0 mg l(-1)). Higher concentrations (1.6-40-fold) of chlorine were required to eradicate biofilm populations of these strains, ~70% of biofilms tested were not eradicated by 5.0 mg l(-1) chlorine. Pathogenic bacteria within the model multi-species biofilms had an even more substantial increase in chlorine tolerance; on average ~700-1100 mg l(-1) chlorine was required to eliminate pathogens from the biofilm, 50-300-fold higher than for biofilms comprising single species. Confocal laser scanning microscopy of biofilms showed distinct 3D structures and multiple cell morphologies and arrangements. Overall, this study showed a substantial increase in the chlorine tolerance of individual species with co-colonization in a multi-species biofilm that was far beyond that expected as a result of biofilm growth on its own.
1.52-1.59-μm range different-wavelength modulator-integrated DFB-LDs fabricated on a single wafer (1998)

We report for the first time different-wavelength modulator-integrated distributed-feedback laser diodes (DFB/MODs) fabricated on a single wafer, whose lasing wavelength cover almost all of the expanded erbium-doped fiber amplifier (EDFA) gain band from 1.527 to 1.593 μm. The devices provided uniform and high-performance characteristics such as a threshold current less than 12 mA and successful transmission of 2.5 Gb/s-600 km through a normal fiber.
The Attorney as Defendant (1961)

In 1925 he became an Associate Justice of the United States Supreme Court
Treatment of Delayed Food Allergy Based on Specific Immunoglobulin G Rast Testing (2000)

This preliminary, descriptive study after extensive clinical experience demonstrates specific IgG food RASTs done in 114 consecutive patients with strong positive histories for delayed food allergy. Elimination of the positive foods was the sole means of treatment. The symptoms leading to the test are detailed, and the method of workup is reviewed. The overall results demonstrated a 71% success rate for all symptoms achieving at least a 75% improvement level. Of particular interest was the group of patients with chronic, disabling symptoms, unresponsive to other intensive treatments. Whereas 70% obtained 75% or more improvement, 20% of these patients obtained 100% relief.
Adenyl Cyclase in Fat Cells (1969)

Abstract Some of the characteristics of adenyl cyclase activity and its response to the stimulatory agents, adrenocorticotropin (ACTH) and fluoride ion, were investigated in rat fat cell ghosts. ACTH and fluoride ion stimulated the activity of the same enzyme. The membrane-bound enzyme was unstable at 0 and 37° and was inactivated by trypsin. Of several monovalent cations tested, lithium ion inhibited the basal, ACTH-, and fluoride-stimulated activities of the enzyme. Potassium ion, at 10 mm, specifically enhanced the response of the enzyme to ACTH; this effect of potassium was abolished by sodium ion (100 mm). The enzyme required a divalent ion for activity; among several divalent cations tested, Mn++, Mg++, and Co++ were effective. Mn++ (5 mm) stimulated basal and fluoride activities but not ACTH activity which showed a preference for Mg++. Ca++ inhibited adenyl cyclase activity; ACTH and fluoride ion reduced the concentration necessary to obtain 50% inhibition from 2.0 mm to 0.75 and 0.40 mm, respectively. The affinity of adenyl cyclase for Mg++ was increased in the presence of ACTH and fluoride ion, whereas the affinity for ATP was not changed. The kinetic characteristics of the basal, ACTH-, and fluoride-stimulated activities of the enzyme in the presence of Mg++ indicated that adenyl cyclase has two binding sites for Mg++, one of which is at the catalytic site and the other at some site that is altered by the actions of ACTH and fluoride ion and which enhances, allosterically, the reaction of the catalytic site with its substrate, MgATP. Although both ACTH and fluoride affected the same kinetic parameter (increased affinity for Mg++), the following differences were observed in their characteristics of activation: (a) Fluoride- and ACTH-stimulated activities were affected differently in the presence of potassium and manganous ions; (b) ACTH concentration curves were hyperbolae whereas fluoride concentration curves were sigmoids; (c) the concentration of ACTH giving half-maximal stimulation (apparent Km) was only slightly affected by temperature, whereas the apparent Km for fluoride activation was changed from 0.9 mm at 37° to 2.0 mm at 30°. It was concluded that ACTH and fluoride ion activate the same enzyme and alter the same kinetic parameter involved in activation, but do so by different means.
The application of echo-tracking methods to endothelium-dependent vasoreactivity and arterial compliance measurements (1996)

Measurements of endothelium-dependent vasoreactivity and arterial compliance are important metrics of vascular pathophysiology which may be used for the development and evaluation of therapeutic methods. The technique of ultrasonic echo tracking is applicable to measurements of endothelium-dependent vasoreactivity and arterial compliance. To evaluate the application of echo tracking to these measurements, we constructed a system based upon analog-to-digital conversion and storage of the radio frequency (RF) ultrasound signals. Off-line analysis of the RF data with various echo-tracking algorithms demonstrated two potential sources of error: tracking drift and RF transition regions. The tracking drift resulted from the slow accumulation of tracking error. The RF transition regions were associated with disparate motions of neighboring reflectors or the insonation of a new series of tissue layers. As a result of these sources of error, the application of echo tracking to endothelium-dependent vasoreactivity measurements is unlikely to outperform duplex ultrasound methods. The application of echo tracking to arterial compliance measurements via the arterial pressure/diameter relationship may produce variable results due to RF transition regions. Finally, the application of echo tracking to arterial compliance measurements via the pulse wave velocity is relatively insensitive to these sources of error because the pulse-wave velocity measurement depends upon the timing of the peak arterial distension, not on the absolute value of the distension.
Synthesis and electrical properties of silver nanoplates for electronic applications (2015)

Abstract In this paper, silver nanoplates of 100 to 500 nm size were synthesized by reduction of silver nitrate with N,Ndimethylformamide, using poly(vinylpyrolidone) as a surfactant and ferric chloride as a controlling agent, at 120 to 160 °C for 5 to 24 hours. The influence of the concentration of ferric chloride, the reaction temperature and reaction time on the morphology of the product has been investigated by transmission electron microscopy, scanning electron microscopy and UV-Vis spectroscopy. The results indicated that the products obtained at the low reaction temperature and short reaction time in the presence of FeCl 3 in the reaction solution were in the form of silver nanoplates, whose morphology was mainly triangular and hexagonal. In addition, the size and thickness of the nanoplates increased with increasing of the FeCl 3 concentration. At a high reaction temperature and long reaction time, the truncated triangle and hexagonal nanoplates were mainly produced. Furthermore, the sintering behavior of nanoplates was studied and the results showed that sintering of the silver nanoplates started at 180 °C, and a typical sintering behavior was observed at higher temperatures. The incorporation of the silver nanoplates into the polymer matrix with micro-sized silver flakes led to an increase in the matrix resistivity in almost all cases, especially at high fractions and low curing temperatures. The curing temperature had an influence on the resistivity of the conductive adhesives filled with micro-sized silver flakes and silver nanoplates due to sintering of the silver nanoplates.
ONE MAN BRIDGE OPERATION (1997)

SUBTITLE: CORRECT BRIDGE DESIGN AND THE RIGHT EQUIPMENT IS CRUCIAL TO OBTAINING A ONE MAN BRIDGE OPERATION CLASS NOTATION.
Interaction of the IL-2 Receptor with the <i>src</i> -Family Kinase p56 <sup>lck</sup> : Identification of Novel Intermolecular Association (1991)

In the interleukin-2 (IL-2) system, intracellular signal transduction is triggered by the beta chain of the IL-2 receptor (IL-2R beta); however, the responsible signaling mechanism remains unidentified. Evidence for the formation of a stable complex of IL-2R beta and the lymphocyte-specific protein tyrosine kinase p56lck is presented. Specific association sites were identified in the tyrosine kinase catalytic domain of p56lck and in the cytoplasmic domain of IL-2R beta. As a result of interaction, IL-2R beta became phosphorylated in vitro by p56lck. Treatment of T lymphocytes with IL-2 promotes p56lck kinase activity. These data suggest the participation of p56lck as a critical signaling molecule downstream of IL-2R via a novel interaction.
IMPROVING SCALABILITY AND FLEXIBILITY OF A DISTRIBUTED WORKFLOW SYSTEM (2001)

Workflow management system (WfMS) has been used to provide a powerful computation environment for integration of different applications and cooperation of different organizations within enterprise. In the current research field of workflow technologies, the distributed workflow engines have gradually caught more and more attentions, and the scalability and flexibility of the whole system are the two critical factors to successful implementation of the distributed workflow system. In this paper, a distributed workflow system with high scalability and high flexibility that runs on different enterprise function domains is introduced. Meanwhile, relevant concept of domain, system infrastructure, implementation of a process instance, and global control mechanism are also presented.
Dissociation of Sulfuric Acid in Aqueous Solution: Determination of the Photoelectron Spectral Fingerprints of H<sub>2</sub>SO<sub>4</sub>, HSO<sub>4</sub><sup>–</sup>, and SO<sub>4</sub><sup>2–</sup> in Water (2013)

In the work described here, the electronic structure of sulfuric acid in water is explored by liquid-jet photoelectron spectroscopy. From the S2p photoelectron spectra of H2SO4 (aq), measured over a large concentration range and aided by previously reported HSO4–/SO42- and HSO4–/H2SO4 concentration ratios in the bulk solution, we obtain detailed electronic structure information of each species. Comparing our results with previous studies on the dissociation of nitric acid, we argue that the solvation structure of H2SO4 (aq) changes around 5–7 M concentration, at which point a dramatic change in both the HSO4– photoelectron peak width and binding energy occurs.
Synthesis of 1-(3′-Azido-2′,3′-dideoxy-α-L-<i>threo</i>-pentofuranosyl)thymine as a Potential Anti-HIV Agent (1991)

Starting from methyl 2,3,5-tri-O-benzoyl-α-L-arabinofuranoside, a multistep synthesis of the C-4′ epimer of AZT is described. Glycosylation of silylated thymine with 2,3,5-tri-O-benzoyl-L-arabinofuranosyl acetate (5) affords the α-nucleoside 7 after debenzoylation. Deoxygenation at C-2′ of the selectively protected 8, followed by displacement of a 3′-methanesulfonyl group by lithium azide leads to the title compound which did not exhibit antiviral activity against HIV-1.
Design of Series Feedback Millimeter Wave Oscillators employing Whispering Gallery Mode Dielectric Resonators (1992)

Design and performance of millimeter wave oscillators at 36.5 GHz and 44.5 GHz employing Whispering Gallery Mode Dielectric Resonators (WGMDR) and commercially available HEMTs are presented. A special microstrip coupling circuit has been developed for the WGMDR. This coupling avoids the mode splitting of the degenerate Whispering Gallery Modes and also avoids out of band instabilities in a series feedback oscillator. Two oscillators at 36.5GHz employing a WGE7,0,0 mode resonator and at 44.5 GHz employing a WGE9,0,0 mode resonator have been designed. High output power(> 7dBm) and efficiency (10%) have been achieved for both oscillators.
In-situ deposited WSi/sub x/ polycide for high frequency transistor gate structures (2002)

This paper describes the implementation of in-situ doped WSi/sub x/ polycide into a manufacturing environment for high frequency communication applications. Process matching, process integration considerations, and statistical characterization of process latitude are described. Outstanding device performance was achieved.
Improved sum-rate optimization in the multiuser MIMO downlink (2008)

We consider linear precoding and decoding in the downlink of a multiuser multiple-input, multiple-output (MIMO) system. In this scenario, the transmitter and the receivers may each be equipped with multiple antennas, and each user may receive more than one data stream. We examine the relationship between the sum capacity for the broadcast channel with channel state information at the transmitter under a sum power constraint and the achievable sum rates under linear precoding. We show that achieving the optimum sum throughput under linear precoding is equivalent to minimizing the product of mean squared error (MSE) matrix determinants. The resulting nonconvex optimization problem is solved numerically, guaranteeing local convergence only. The performance of this approach is analyzed via comparison to the sum capacity and to existing approaches for linear precoding.
Genome-Wide Transcriptional Profiling Reveals Connective Tissue Mast Cell Accumulation in Bronchopulmonary Dysplasia (2012)

We present a unique genome-wide expression data set from human BPD lung tissue. Our data provide information on gene expression patterns associated with BPD and facilitated the discovery that MC(TC) accumulation is a prominent feature of this disease. These observations have significant clinical and mechanistic implications.
2‐<i>trans</i>,4‐<i>cis</i>,7‐<i>cis</i>‐Decatrienal, the fishy off‐flavor occurring in strongly autoxidized oils containing linolenic acid or ω 3,6,9, etc., fatty acids (1972)

Abstract A possible decomposition product of oils containing unsaturated fatty acids with the double bond pattern ω3,6,9 or ω3,6,9, etc., is 2‐ trans ,4‐ cis ,7‐ cis ‐decatrienal. It has therefore been investigated whether this trienal is present in strongly autoxidized linolenic acid, soybean, linseed and fish oils. Via a degassing technique the carbonyls from the samples of oils heated in a closed system under nitrogen were collected and separated as their 2,4‐dinitrophenylhydrazones (DNPHs) by thin layer chromatography (TLC). The presence of 2‐ trans ,4‐ cis ,7‐ cis ‐decatrienal in the samples was positively established by TLC, UV absorption and mass spectroscopy of its DNPH. All analytical data established the complete identity of the isolated DNPH with a synthesized 2,4,7‐decatrienal‐DNPH. The free aldehyde obtained on hydrolysis of the alkatrienal‐DNPH in question had the same flavor as authentic 2‐ trans ,4‐ cis ,7‐ cis ‐decatrienal, having a fish or rather a whale oil flavor.
<scp>l</scp>‐DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice (2008)

In the dopamine-depleted striatum, extracellular signal-regulated kinase (ERK) signaling is implicated in the development of L-DOPA-induced dyskinesia. To gain insights on its role in this disorder, we examined the effects of L-DOPA on the state of phosphorylation of ERK and downstream target proteins in striatopallidal and striatonigral medium spiny neurons (MSNs). For this purpose, we employed mice expressing enhanced green fluorescent protein (EGFP) under the control of the promoters for the dopamine D(2) receptor (Drd2-EGFP mice) or the dopamine D(1) receptor (Drd1a-EGFP mice), which are expressed in striatopallidal and striatonigral MSNs, respectively. In 6-hydroxydopamine-lesioned Drd2-EGFP mice, L-DOPA increased the phosphorylation of ERK, mitogen- and stress-activated kinase 1 and histone H3, selectively in EGFP-negative MSNs. Conversely, a complete co-localization between EGFP and these phosphoproteins was observed in Drd1a-EGFP mice. The effect of L-DOPA was prevented by blockade of dopamine D(1) receptors. The same pattern of activation of ERK signaling was observed in dyskinetic mice, after repeated administration of L-DOPA. Our results demonstrate that in the dopamine-depleted striatum, L-DOPA activates ERK signaling specifically in striatonigral MSNs. This regulation may result in ERK-dependent changes in striatal plasticity leading to dyskinesia.
Sterilization of hydrogels for biomedical applications: A review (2017)

Despite the beneficial properties and outstanding potential of hydrogels for biomedical applications, several unmet challenges must be overcome, especially regarding to their known sensitivity to conventional sterilization methods. It is crucial for any biomaterial to withstand an efficient sterilization to obtain approval from regulatory organizations and to safely proceed to clinical trials. Sterility assurance minimizes the incidence of medical device-related infections, which still constitute a major concern in health care. In this review, we provide a detailed and comprehensive description of the published work from the past decade regarding the effects of sterilization on different types of hydrogels for biomedical applications. Advances in hydrogel production methods with simultaneous sterilization are also reported. Terminal sterilization methods can induce negative or positive effects on several material properties (e.g., aspect, size, color, chemical structure, mechanical integrity, and biocompatibility). Due to the complexity of factors involved (e.g., material properties, drug stability, sterilization conditions, and parameters), it is important to note the virtual impossibility of predicting the outcome of sterilization methods to determine a set of universal rules. Each system requires case-by-case testing to select the most suitable, effective method that allows for the main properties to remain unaltered. The impact of sterilization methods on the intrinsic properties of these systems is understudied, and further research is needed. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 2472-2492, 2018.
Biotransformations of Selenium Oxyanion by Filamentous Cyanophyte-Dominated Mat Cultured from Agricultural Drainage Waters (1998)

A filamentous cyanophyte-dominated mat was cultured from waters of a large agricultural drainage evaporation basin in California. This mat was active in volatilizing Se from selenite at 20−10 000 μg/L Se, which accounted for >60% of the Se loss from the medium. Up to 75% of the medium Se was depleted over a 50-day period. This demonstrates a potentially important mechanism contributing to the nearly 100% loss of waterborne Se persistently observed at that basin. Se volatilization was via dimethylselenide, dimethyldiselenide, and dimethylselenenylsulfide, with evidence that the precursors were methylselenomethionine and methylselenocysteine but not dimethylselenonium propionate or trimethylselenonium ion. Selenite was also incorporated into proteins primarily in the form of selenomethionine at external Se concentrations of 5000 μg/L Se or higher, which may account for the slow growth of the cyanophyte mat at these concentrations. Such Se metabolite characterization in aquatic producers is important for understanding the role of Se biogeochemistry in ecotoxicity, which is vital for development of environmentally sound in situ Se bioremediation.
Functional autonomic nervous system profile in children with autism spectrum disorder (2014)

Our data suggest overall autonomic hyperarousal in ASD and selective atypical reactivity to social tasks.
Antimicrobial Activities of Single Aroma Compounds (2010)

Commercially available aroma samples were evaluated for their olfactory quality by professional perfumers and tested for their antimicrobial activity. Agar diffusion and agar-dilution were used as test methods and a set of two Gram-positive (Staphylococcus aureus and Enterococcus faecalis) and four Gram-negative bacterial strains (Escherichia coli, Pseudomonas aeruginosa, Proteus vulgaris G, Klebsiella pneumoniae and Salmonella abony) and a yeast, Candida albicans, were the test microorganisms. All the investigated compounds were active against Gram-positive bacteria, especially beta-caryophyllene against Enterococcus faecalis (MIC 6 ppm), but only few substances showed activity towards Gram-negative bacteria, except for cinnamic acid, which was active against all (MIC 60 ppm) and Candida albicans, against which cinnamic acid and caryophyllene oxide showed high activity (MIC < 60 ppm).