ENDOCRINE REGULATION OF THE BLOOD SUGAR (1953)

Article1 February 1953ENDOCRINE REGULATION OF THE BLOOD SUGARJEROME W. CONN, M.D., F.A.C.P.JEROME W. CONN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-2-179 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptOf all of the presently recognized metabolic disturbances which arise in man as the result of deranged endocrine function, diabetes mellitus is the most common. As a clinical entity it has been known, studied and treated by physicians for many years. Because of the tremendous impact upon medical science of the isolation of insulin by Banting and Best in 1921, the historical details of the disease itself are known to virtually all whose interests fall into the general realm of biology. Much of our present knowledge in the fields of nutrition, metabolism and modern endocrinology stems from basic facts derived...Bibliography1. DruryWickMacKay DRANEM: Formation of glucose by the kidney, Am. J. Physiol. 163: 655, 1950. CrossrefMedlineGoogle Scholar2. ColowickCoriSlein SPGTMW: The effect of adrenal cortex and anterior pituitary extracts and insulin on the hexokinase reaction, J. Biol. Chem. 168: 583, 1947. CrossrefMedlineGoogle Scholar3. Sutherland EW: The effect of hyperglycemic factor of the pancreas and of epinephrine on glycogenosis, Recent Progress in Hormone Research 5: 441, 1950. Google Scholar4. BornsteinReidYoung JEFG: The hyperglycaemic action of blood from animals treated with growth hormone, Nature, London 168: 903, 1951. CrossrefMedlineGoogle Scholar5. Young FG: Permanent experimental diabetes produced by pituitary (anterior lobe) injections, Lancet 2: 372, 1937. CrossrefGoogle Scholar6. RichardsonYoung KCFG: Histology of diabetes induced in dogs by injection of anterior-pituitary extracts, Lancet 1: 1098, 1938. CrossrefGoogle Scholar7. CampbellLeiDavidson JHPIW: Production of diabetes and increased erythrocyte sedimentation rate by purified growth hormone, Endocrinology 49: 635, 1951. CrossrefMedlineGoogle Scholar8. EngleViauCogginsLynn FLAWWS: Diabetogenic effect of growth hormone in the intact force-fed adrenocorticotrophin treated rat, Endocrinology 50: 100, 1952. CrossrefMedlineGoogle Scholar9. Ingle DW: The production of glycosuria in the normal rat by means of 17-hydroxy-11-dihydrocorticosterone, Endocrinology 29: 649, 1942. Google Scholar10. IngleLiEvans DWCHHM: The effect of adrenocorticotrophic hormone on the urinary excretion of sodium chloride, potassium, nitrogen, and glucose in normal rats, Endocrinology 39: 32, 1946. CrossrefMedlineGoogle Scholar11. ConnLouisJohnston JWLHMW: Studies upon mechanisms involved in the induction with adrenocorticotropic hormone of temporary diabetes mellitus in man, Proc. Am. Diabetes A. 8: 213, 1948. Google Scholar12. GershbergFryBrobeckLong HEGJRCN: The rôle of epinephrine in the secretion of the adrenal cortex, Yale J. Biol. and Med. 23: 32, 1950. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Ann Arbor, Michigan*From the Symposium on Diabetes, presented at the Thirty-third Annual Session of the American College of Physicians, Cleveland, Ohio, April 25, 1952. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byGlycosuria�ber die Bestimmung von Insulin im Blute am epididymalen Fettanhang der Ratte mit Hilfe markierter GlucoseDas PankreasGlucagon: Physiologic and Clinical ConsiderationsSurgery of the Diabetic Patient: Changing ConceptsTHE PARADOXICAL EFFECT OF INTRAVENOUS HYDROCORTISONE UPON CARBOHYDRATE METABOLISMInsulin-Resistant Diabetes after Total Pancreatectomy 1 February 1953Volume 38, Issue 2Page: 179-187KeywordsBlood sugarDiabetes mellitusEndocrinologyFallsInsulinNutrition ePublished: 1 December 2008 Issue Published: 1 February 1953 Copyright & PermissionsCopyright, 1953, by The American College of PhysiciansPDF downloadLoading ...