gebhart/patrepeval huggingface dataset:
Edema of the spinal cord following experimental impact trauma (1973)

✓ Identification of central nervous system edema is based on increased water content in relation to nonvolatile residue per unit weight. Nonvolatile residue in spinal cord tissue following impact trauma was determined to ascertain the magnitude and persistence of edema. High and low thoracic laminectomies were carried out on each of 17 rhesus monkeys. The lower exposed cord was traumatized with a calibrated blow of 300 gm cm. All upper exposed cords and the lower exposed cord in one monkey served as nontraumatized controls. At time intervals of 5 minutes to 20 days after trauma, cord segments were removed and assayed for water content. Increased tissue water was evident within 5 minutes and persisted for 15 days. By the 20th day it had essentially subsided. Increased tissue water content in the traumatized segment reached a maximum of 7.4% over control values at 5 days and then gradually diminished. These findings support the concept that edema following spinal trauma is unrelated to secondary effects of ischemia after 18 hours. The protracted course of increased water content (15 to 20 days) was unexpected and may indicate that edema-reducing measures should be continued for 2 to 3 weeks following spinal cord trauma with severe neurological dysfunction.
Rutherford back-scattering study on Xe flash lamp annealing of<sup>31</sup>P<sup>+</sup>ion implanted Si (1984)

The Rutherford back-scattering method was applied to observe the Xe flash lamp annealing process of 31P+ ion implanted (100) Si wafers, the lamp energy being 15-28 J cm-2. The n-type Si wafers with resistivity 20 Omega cm were implanted with 1*1014-3*1015 31P+ ions cm-2 at 50 keV. For the Si wafers implanted with 1*1014 31P+ ions cm-2, the disordered region produced by implantation can be completely annealed at some lamp energies. With higher doses than 1015 31P+ ions cm-2, residual disorders can be observed and there exists on optimum lamp energy which depends on the ion dose, for example 25 J cm-2 for 1*1015 31P+ ions cm-2 20 J cm-2 for 3*1015 31P+ ions cm-2.
New Insight into Site-Specific Recombination from Flp Recombinase-DNA Structures (2003)

The lamba integrase, or tyrosine-based family of site-specific recombinases, plays an important role in a variety of biological processes by inserting, excising, and inverting DNA segments. Flp, encoded by the yeast 2-mum plasmid, is the best-characterized eukaryotic member of this family and is responsible for maintaining the copy number of this plasmid. Over the past several years, structural and biochemical studies have shed light on the details of a common catalytic scheme utilized by these enzymes with interesting variations under different biological contexts. The emergence of new Flp structures and solution data provides insights not only into its unique mechanism of active site assembly and activity regulation but also into the specific contributions of certain protein residues to catalysis.
Measurements of major locality phases in symbolic reference strings (1976)

Previous studies have shown that a program's behavior can be characterized as a sequence of transitions between phases of execution during which some subset of the program's segments is referenced. The nature of the phases (sometimes called localities or regimes), and the characteristics of the transitions between neighboring phases, will determine the performance of the program on a virtual memory system. We here investigate methods for identifying those “major” phases in programs which correspond to intervals of distinctive referencing behavior. Experimental measurements on symbolic reference strings generated by production Algol-60 programs are used to determine the properties of these phases and the transitions between them. The experimental results are discussed in terms of current models for program behavior and also with regard to their implications for memory management systems.
Phase I clinical trial of mitozolomide. (1985)

Mitozolomide (NSC-353451; CCRG 81010; M and B 39565) is a novel potential anticancer agent that was selected for phase I study on the basis of broad spectrum activity in mouse tumors. Initially, mitozolomide was given iv as a short infusion to 37 patients in doses ranging from 8 to 153 mg/m2. Nausea and vomiting was dose-related but was not severe. The dose-limiting toxic effect was thrombocytopenia at doses greater than 115 mg/m2, and recovery from the thrombocytopenia was delayed up to 8 weeks. Partial responses were seen in two patients with adenocarcinoma of the ovary. The pharmacokinetics of mitozolomide showed that the half-life of the intact drug in the plasma was between 1 and 1.3 hours. The area under the curve was proportional to the dose administered. Mitozolomide is well-absorbed; therefore, future studies are recommended using a single-dose schedule orally or iv. In the phase I study reported here, a dose of 115 mg/m2 appeared to be safe, but additional studies have shown that when given orally to an older population, most patients experienced thrombocytopenia less than 50,000 cells/mm3. The recommended dose using current data is 90 mg/m2 iv or orally.
Pyrimidines. IV. Aziridinylpyrimidines<sup>1</sup> (1961)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPyrimidines. IV. Aziridinylpyrimidines1HENRY C. KOPPEL, ROBERT HENRE SPRINGER, and C. C. CHENGCite this: J. Org. Chem. 1961, 26, 6, 1884–1890Publication Date (Print):June 1, 1961Publication History Published online1 May 2002Published inissue 1 June 1961https://pubs.acs.org/doi/10.1021/jo01065a047https://doi.org/10.1021/jo01065a047research-articleACS PublicationsRequest reuse permissionsArticle Views183Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Epitaxial PbTiO3 thin films grown by organometallic chemical vapor deposition (1991)

Epitaxial PbTiO3 layers have been grown on (001)SrTiO3 substrates by organometallic chemical vapor deposition using the precursors titanium-iso-propoxide and tetra-ethyl-lead. The growth temperature for these films was around 700 °C. The epitaxial nature of c-axis-oriented PbTiO3 is confirmed by Rutherford backscattering spectrometry, x-ray diffraction, including pole figure analysis, and high-resolution electron microscopy (HREM). With HREM twinning has been observed.
Simulation-Based Regression Models to Estimate Bus Routes and Network Travel Times (2013)

This paper presents an approach to estimate bus route and network travel times using micro-simulation. This can be used in predicting the effectiveness of bus route designs using some network traffic measures or indicators. The used indicators are average network traffic intensity, posted speeds, route length, frequency of bus operation, and average passenger loadings (boarding and alighting). Regression models are calibrated to predict both route and overall network travel times. The prediction errors of these models were investigated and analyzed, and regression models were validated. Results indicated the validity of the calibrated regression models. Conclusions are made on how the devised models can be validated in reality and used for route planning purposes to determine best operating conditions such as the frequency.
<i>In Vivo</i> Anastomosis and Perfusion of a Three-Dimensionally-Printed Construct Containing Microchannel Networks (2015)

The field of tissue engineering has advanced the development of increasingly biocompatible materials to mimic the extracellular matrix of vascularized tissue. However, a majority of studies instead rely on a multiday inosculation between engineered vessels and host vasculature rather than the direct connection of engineered microvascular networks with host vasculature. We have previously demonstrated that the rapid casting of three-dimensionally-printed (3D) sacrificial carbohydrate glass is an expeditious and a reliable method of creating scaffolds with 3D microvessel networks. Here, we describe a new surgical technique to directly connect host femoral arteries to patterned microvessel networks. Vessel networks were connected in vivo in a rat femoral artery graft model. We utilized laser Doppler imaging to monitor hind limb ischemia for several hours after implantation and thus measured the vascular patency of implants that were anastomosed to the femoral artery. This study may provide a method to overcome the challenge of rapid oxygen and nutrient delivery to engineered vascularized tissues implanted in vivo.
Planar waveguides in multicomponent glasses fabricated by field-driven differential drift of cations (2002)

The fabrication of planar waveguides by a constant-current thermal poling procedure in multicomponent glasses rich in alkali or alkaline earth ions is described. Near the anode, the dc electric field applied to the substrate separates the mobile cations into regions according to their mobility. Each region presents a different refractive index, allowing a waveguide to be formed. This method produces waveguides with an index increase greater than 10(-2) in soda-lime glass with no external ion source, and the waveguides are buried beneath the substrate surface without an additional step.
The investigation of Fmoc-cysteine derivatives in solid phase peptide synthesis. (1992)

Fmoc-Cys(t-Bu)-OH, Fmoc-Cys(Acm)-OH, and Fmoc-Cys(Trt)-OH exhibit excellent synthesis characteristics when used in Fmoc solid phase peptide synthesis on the Applied Biosystems Model 431A peptide synthesizer. The actual 5% scavenger mixture will vary according to the particular amino acid residues present. As was previously mentioned, an anisole/ethanedithiol/ethylmethylsulfide mixture (3:1:1) works well as a general scavenger solution for TFA cleavage of Fmoc synthesized peptide resins. It also may be possible to use lower acid (TFA) concentrations. The syntheses and workups of the peptide Somatostatin utilizing these derivatives demonstrate the ease of using these cysteine derivatives with the Fmoc chemistry approach. The use of either the t-Bu or the Acm moiety produces a peptide containing protected thiol groups after cleavage with 95% TFA. The Fmoc-Cys(Trt)-OH derivative is efficiently deprotected using 95% TFA. This investigation should provide further insight into synthesis options and cleavage protocols when working with cysteine-containing peptides.
Design of a silicon-plasmonic hybrid electro-optic modulator (2012)

We propose a racetrack ring based optical modulator employing an electro-optic polymer infiltrated silicon-plasmonic hybrid phase shifter. From simulation results, an extinction ratio of higher than 15 dB is achieved at 1550-nm wavelength under a 1.2-V bias. A modulation bandwidth of more than 100 GHz can be potentially obtained due to a fast response speed of the Pockels effect, a reduced RC delay, and a decreased quality factor of the ring.
Optical rotation per refractive index unit, or enantiomeric (e) factor, for screening enantioselective catalysts through asymmetric activation or carbohydrates (2000)

A super high-throughput screening (SHTS) system can be constructed by combining high-performance liquid chromatography (HPLC), optical rotation (OR), and refractive index unit (RIU) to determine not only the enantioselectivity of the addition of diethylzinc to an aliphatic aldehyde catalyzed by a binaphthol-zinc complex through asymmetric activation with chiral Schiff bases, but also the enantiopurity of a carbohydrate. The enantiomeric (e) factor, which we define here as optical rotation per refractive index unit, is linearly related to the percent enantiomeric excess (%ee) and is independent of concentration. Chirality 12:544–547, 2000. © 2000 Wiley-Liss, Inc.
Chondroitin Sulfate Glycosaminoglycan Hydrogels Create Endogenous Niches for Neural Stem Cells (2015)

Neural stem cells (NSCs) possess great potential for neural tissue repair after traumatic injuries to the central nervous system (CNS). However, poor survival and self-renewal of NSCs after injury severely limits its therapeutic potential. Sulfated chondroitin sulfate glycosaminoglycans (CS-GAGs) linked to CS proteoglycans (CSPGs) in the brain extracellular matrix (ECM) have the ability to bind and potentiate trophic factor efficacy, and promote NSC self-renewal in vivo. In this study, we investigated the potential of CS-GAG hydrogels composed of monosulfated CS-4 (CS-A), CS-6 (CS-C), and disulfated CS-4,6 (CS-E) CS-GAGs as NSC carriers, and their ability to create endogenous niches by enriching specific trophic factors to support NSC self-renewal. We demonstrate that CS-GAG hydrogel scaffolds showed minimal swelling and degradation over a period of 15 days in vitro, absorbing only 6.5 ± 0.019% of their initial weight, and showing no significant loss of mass during this period. Trophic factors FGF-2, BDNF, and IL10 bound with high affinity to CS-GAGs, and were significantly (p < 0.05) enriched in CS-GAG hydrogels when compared to unsulfated hyaluronic acid (HA) hydrogels. Dissociated rat subventricular zone (SVZ) NSCs when encapsulated in CS-GAG hydrogels demonstrated ∼88.5 ± 6.1% cell viability in vitro. Finally, rat neurospheres in CS-GAG hydrogels conditioned with the mitogen FGF-2 demonstrated significantly (p < 0.05) higher self-renewal when compared to neurospheres cultured in unconditioned hydrogels. Taken together, these findings demonstrate the ability of CS-GAG based hydrogels to regulate NSC self-renewal, and facilitate growth factor enrichment locally.
TiO<sub>2</sub>‐, ZnO‐, and CdS‐photocatalyzed oxidation of ethylene‐propylene thermoplastic elastomers (1987)

Abstract The ZnO‐, TiO 2 ‐, and CdS‐photocatalyzed oxidations of an amorphous ethylene‐propylene copolymer ( EP copolymer) containing 75% w/w of ethylene are described. In solid films exposed under polychromatic (λ > 300 nm) or monochromatic (λ = 365 nm) UV light, it is observed that the introduction of pigment (0.5–5% w/w) strongly modified the course of the photooxidation of a transparent sample. Ketonic and lactonic groups accumulate in the polymer matrix without being converted photochemically into acidic, ester, and vinyl groups. In the kinetic study it is pointed out that the variations of the rate of formation of carbonyl groups depend on the nature of the pigment. With highly photoactive pigments (ZnO and untreated TiO 2 RL11A), the rate is at first a decreasing function of the pigment percent, then an increasing function. With poorly photoactive pigments (treated TiO 2 RL90 and CdS), the rate of formation of carbonyl groups is a decreasing function of the pigment content. It is therefore emphasized that, at a low pigment content, the inner filter effect prevails over the photocatalytic influence with any pigment. It is also observed that the rate of formation of vinyl groups, photoproducts formed from the excited ketones, is a monotonously decreasing function of the pigment content. The complete inhibition of the ketone photochemistries is observed with ZnO in conditions in which the light is not absorbed by the pigment, suggesting that the carbonyl groups formed are adsorbed on the pigment.
Observed response of the hudson river plume to wind forcing using a nested HF radar array (2005)

One objective of the Lagrangian Transport and Transformation Experiment (LaTTE) is to determine the relative advantages of studying the Hudson River plume within the spatial and temporal context provided by an operational research observatory. Towards this end, a shelf-wide observational backbone was locally enhanced with high-resolution relocatable systems in the New York Bight apex. The permanent backbone includes local acquisition of international satellite ocean color imagery, a network of long-range High Frequency radars, and a cross-shelf Endurance line occupied by an autonomous underwater glider. The high resolution systems, including higher resolution HF Radar, glider and mooring networks, were moved to the New York Bight Apex to support the specific interdisciplinary process study. During the LaTTE field effort, datasets from the nested observation network, including a triple nested HF Radar array, were assembled in real-time at a shore-based acquisition center, and high-resolution atmospheric forecasts were performed. Surface current observations will be reviewed, with specific emphasis placed on the observed response of the Hudson River plume to local winds. The observatory results provide a spatial and temporal context for viewing the LaTTE dye release, chemical and biological results.
The Amt/Mep/Rh family of ammonium transport proteins (Review) (2007)

The Amt/Mep/Rh family of integral membrane proteins comprises ammonium transporters of bacteria, archaea and eukarya, as well as the Rhesus proteins found in animals. They play a central role in the uptake of reduced nitrogen for biosynthetic purposes, in energy metabolism, or in renal excretion. Recent structural information on two prokaryotic Amt proteins has significantly contributed to our understanding of this class, but basic questions concerning the transport mechanism and the nature of the transported substrate, NH3 or [NH4(+)], remain to be answered. Here we review functional and structural studies on Amt proteins and discuss the bioenergetic issues raised by the various mechanistic proposals present in the literature.
Experimental Inorganic Chemistry (1954)

Experimental inorganic chemistry , Experimental inorganic chemistry , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی
Halogenierte Pyridine III. Di‐ und trihalogenierte Pyridin‐3‐aldehyde (1976)

Halogenated pyridines III. Di‐ and trihalogenated pyridine‐3‐aldehydes . Three methods for the preparation of new ring chlorinated pyridine‐3‐aldehydes are investigated. Reactions of the new aldehydes are reported.
IBRNet: Learning Multi-View Image-Based Rendering (2021)

We present a method that synthesizes novel views of complex scenes by interpolating a sparse set of nearby views. The core of our method is a network architecture that includes a multilayer perceptron and a ray transformer that estimates radiance and volume density at continuous 5D locations (3D spatial locations and 2D viewing directions), drawing appearance information on the fly from multiple source views. By drawing on source views at render time, our method hearkens back to classic work on image-based rendering (IBR), and allows us to render high-resolution imagery. Unlike neural scene representation work that optimizes per-scene functions for rendering, we learn a generic view interpolation function that generalizes to novel scenes. We render images using classic volume rendering, which is fully differentiable and allows us to train using only multi-view posed images as supervision. Experiments show that our method outperforms recent novel view synthesis methods that also seek to generalize to novel scenes. Further, if fine-tuned on each scene, our method is competitive with state-of-the-art single-scene neural rendering methods. Project page: https://ibrnet.github.io/
Anomaly detection in crowd scene (2010)

Anomaly detection in crowd scene is very important because of more concern with people safety in public place. This paper presents an approach to automatically detect abnormal behavior in crowd scene. For this purpose, instead of tracking every person, KLT corners are extracted as feature points to represent moving objects and tracked by optical flow technique to generate motion vectors, which are used to describe motion. We divide whole frame into small blocks, and motion pattern in each block is encoded by the distribution of motion vectors in it. Similar motion patterns are clustered into pattern model in an unsupervised way, and we classify motion pattern into normal or abnormal group according to the deviation between motion pattern and trained model. The results on abnormal events detection in real video demonstrate the effectiveness of the approach.
High-Fiber Diets in the Treatment of Diabetes Mellitus (1978)

Eight patients with insulin-requiring diabetes were given, in random order, a diet containing 3 g and one containing 20 g of crude fiber. Each diet was maintained for 10 days and was the same in calories, carbohydrate, fat, and protein. Insulin dose was kept constant. Mean plasma glucose on the low-fiber diet was 169.4 +/- 11.7 mg/dl, significantly higher (P less than 0.001) than the value of 120.8 +/- 10.1 on the high-fiber diet. Hypoglycemic reactions were more common on the high-fiber diet. Weight remained essentially constant on both diets. Mean serum glucagon level on the high-fiber diet was significantly lower (P less than 0.001) than on the low-fiber diet, while serum free insulin levels were unchanged. These data indicate that substantial changes in fiber content of the diabetic diet may lead to marked changes in diabetic control and that increasing dietary fiber may be a useful means of lowering plasma glucose in some diabetic patients.
Spectrophotometric Determination of Vicinal Glycols (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpectrophotometric Determination of Vicinal GlycolsJ. S. Dixon and David. LipkinCite this: Anal. Chem. 1954, 26, 6, 1092–1093Publication Date (Print):June 1, 1954Publication History Published online1 May 2002Published inissue 1 June 1954https://pubs.acs.org/doi/10.1021/ac60090a046https://doi.org/10.1021/ac60090a046research-articleACS PublicationsRequest reuse permissionsArticle Views287Altmetric-Citations359LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts