gebhart/patrepeval huggingface dataset:
Analysis and design of a three-phase LCC-type resonant converter (1998)

A three-phase dc-to-dc LCC-type resonant converter with high-frequency transformer isolation is proposed. The operation and a simple analysis of the converter are presented. Design curves are obtained and a design example is given. SPICE simulation and experimental results are presented to verify the performance of the proposed converter for varying load conditions. The converter proposed has several advantages, e.g., operation in lagging PF mode for the entire load range, requires a narrow variation required in switching frequency, reduced component size and stresses, etc.
ErbB2 Transgenic Mice: A Tool for Investigation of the Immune Prevention and Treatment of Mammary Carcinomas (2008)

The epidermal growth factor receptor belongs to a superfamily of receptor tyrosine kinases (RTK) that includes ErbB2. ErbB2 is involved in normal physiological processes, such as embryogenesis, cell proliferation, differentiation, adhesion motility, and apoptosis, while its malfunction or overexpression is responsible for development defects, diabetes, and cancer. The human ortholog of ErbB2 is referred as Her-2 (human ErbB2) while the rat ortholog is referred as neu (rat ErbB2). As ErbB2 is directly involved in carcinogenesis, mice transgenic for the rat neu oncogene allow straightforward assessment of the ability of drugs and vaccines to inhibit the progression of neu-driven cancer. Information from this model may provide indications on the efficacy of similar treatments in patients. This commentary provides key information regarding the use of these transgenic mouse models for evaluation of the efficacy of anti-tumor strategies.
Improving the Performance of the Prony Method Using a Wavelet Domain Filter for MRI Denoising (2014)

The Prony methods are used for exponential fitting. We use a variant of the Prony method for abnormal brain tissue detection in sequences of T 2 weighted magnetic resonance images. Here, MR images are considered to be affected only by Rician noise, and a new wavelet domain bilateral filtering process is implemented to reduce the noise in the images. This filter is a modification of Kazubek's algorithm and we use synthetic images to show the ability of the new procedure to suppress noise and compare its performance with respect to the original filter, using quantitative and qualitative criteria. The tissue classification process is illustrated using a real sequence of T 2 MR images, and the filter is applied to each image before using the variant of the Prony method.
An Adaptive-Clocking-Control Circuit With 7.5% Frequency Gain for SPARC Processors (2017)

On-die supply-voltage droops attributed to workload variations degrade the performance of high-performance microprocessors. An adaptive-clocking-control circuit was implemented for mitigating the adverse impact of supply-voltage droops on processor performance. One of the most critical requirements for adaptive-clocking supply-droop mitigation is that clock-frequency adaptation is fast enough to respond to such supply droops. To shorten the clock-frequency-adaptation latency, therefore, the adaptive-clocking-control circuit features the following schemes: the time-to-digital converter (TDC) based on multipath delay line (multipath TDC), thermometer-code-based data-processing logic, and phase-locked loop (PLL) including a direct frequency-reduction mechanism. The multipath TDC reduces quantization errors in droop detection to shorten detection-response latency. The thermometer-code-based logic does not cost extra clock cycles compared with binary-code-based logic. The direct frequency-reduction mechanism enables a PLL to quickly react to clock-modulation instruction without any intervals. These schemes contribute to faster clock-frequency-adaptation response to supply droops. A test chip including the adaptive-clocking-control circuit with SPARC processor cores was fabricated in a 20-nm CMOS process. Experimental measurements indicate that the adaptive-clocking-control circuit achieved a state-of-the-art frequency gain of 7.5%, resulting in an operating frequency as high as 5 GHz.
Real-time 3D face modeling with a commodity depth camera (2013)

We propose a system that enables a person to quickly and easily generate a high-quality 3D model of their face using a low-cost depth camera such as the Kinect. The Kinect sensor provides depth images at video-rate, however, the depth images are often noisy and contain holes. Our system builds high-quality 3D face models by registering and integrating multiple depth images of a user's head. This method allows a user to generate a model of their face by simply moving their head in front of a fixed depth camera. Our method is built upon the KinectFusion system with modifications to enable segmented depth images to be robustly registered and integrated. Furthermore, we present a fast technique to segment a user's head from a depth image. Our system is able to run at a real-time rate on commodity hardware.
Hierarchical Assembly of Viral Nanotemplates with Encoded Microparticles via Nucleic Acid Hybridization (2008)

We demonstrate hierarchical assembly of tobacco mosaic virus (TMV)-based nanotemplates with hydrogel-based encoded microparticles via nucleic acid hybridization. TMV nanotemplates possess a highly defined structure and a genetically engineered high density thiol functionality. The encoded microparticles are produced in a high throughput microfluidic device via stop-flow lithography (SFL) and consist of spatially discrete regions containing encoded identity information, an internal control, and capture DNAs. For the hybridization-based assembly, partially disassembled TMVs were programmed with linker DNAs that contain sequences complementary to both the virus 5' end and a selected capture DNA. Fluorescence microscopy, atomic force microscopy (AFM), and confocal microscopy results clearly indicate facile assembly of TMV nanotemplates onto microparticles with high spatial and sequence selectivity. We anticipate that our hybridization-based assembly strategy could be employed to create multifunctional viral-synthetic hybrid materials in a rapid and high-throughput manner. Additionally, we believe that these viral-synthetic hybrid microparticles may find broad applications in high capacity, multiplexed target sensing.
Classifying agricultural land uses with time series of satellite images (2012)

Use of temporal signatures to classify the complex land use patterns in Canterbury New Zealand is investigated. Two datasets of detailed field histories spanning 5-7 years are used to develop a rule set for classifying from satellite imagery (SPOT/Landsat). While many individual crops proved inseparable, a broader set of land use classes such as `winter forage' or `summer arable crop' were defined that could be separated with accuracies between 71% and 96% (averaging 82% over 8 classifications). These broader land use classes will be used in a second stage of the project to guide and constrain classifications incorporating spectral information from the crop's peak NDVI phase.
Subclinical Markers of Human Inflammatory Bowel Disease (1995)

Genetic studies can be greatly aided by the use of subclinical markers that are closer to the basic defect and thus likely to detect more individuals with the abnormal genotype. At least two approaches are generally used to characterize subclinical markers. One is the family study approach. The detection of subclinical abnormalities in unaffected relatives similar to those found in the probands can distinguish between an inherited predisposition and a secondary abnormality due to the disease process. The second approach is the combination of subclinical marker with genetic marker studies. Specific association of a subclinical marker with a genetic marker indicates genetic determination of the subclinical marker. The identification of a genetically determined subclinical marker can help to define a more homogeneous disease group for genetic studies. The most studied subclinical markers in inflammatory bowel disease (IBD) are antineutrophil cytoplasmic antibodies (ANCAs) for ulcerative colitis (UC) and intestinal permeability for Crohn′s disease (CD). Even so, for these as well as several other promising subclinical markers, there is an obvious need for more twin, family and genetic marker studies. An elevated intestinal permeability in a proportion of unaffected relatives of CD patients has been observed in the majority of family studies. ANCAs, a highly specific marker for UC, have been found with a significantly increased prevalence in unaffected relatives of UC patients compared with spouses of the patients. Moreover, the distribution of the ANCAs is familial rather than random, suggesting heterogeneity within UC. In combination with genetic marker studies (human leukocyte antigen [HLA] class II genes), the authors observed a differential association: ANCA‐positive UC was associated with DR2, while ANCA‐negative UC associated with DR4. These data lead to the conclusion that the heterogeneity indicated by ANCA is genetically determined and that this genetic heterogeneity should be taken into consideration in future genetic, clinical and pathophysiological studies. In the aggregate, these data indicate that the subclinical marker approach is a powerful means for demonstrating genetic and etiological heterogeneity, and can be an important tool to define the etiology and natural history of the various diseases that make up IBD.
Carrier scattering and transport in semiconductors treated by the energy-loss method (1986)

The energy-loss method has been applied for more than ten years to a large variety of transport problems. The surprising success apparently is due to the simplicity of the concept as well as of the mathematical treatment. In addition to a previous review (by Gerlach and Grosse) where a number of formulae for basic applications were derived and compared with experiments, the author gives a general intuitive and analytic introduction into the method and the general structure of the results. Furthermore, he describes recent fields of application. Most important are scattering of impurities by clusters, by ions near surfaces, and by dislocations and precipitations. A new interesting feature is a localisation of carriers appearing in low-conduction systems. A most recent application of the energy-loss method concerns drifting carrier systems and transport in external magnetic fields. Finally he discusses the relation of the energy loss to a force balance and report results on electron-electron scattering and the effect of polar optical phonons on transport coefficients.
New prospects for treatment of lupus nephritis. (2000)

Systemic lupus erythematosus (SLE) is envisioned to arise from hyperactivate helper T-cells that cause polyclonal B-cell secretion of pathogenic autoantibodies and formation of immune complexes which deposit in sites such as the kidney. The most widely used immunosuppressive drugs, notably corticosteroids and cyclophosphamide, are often criticized as being nonspecific. In fact, these agents may be effective in SLE and lupus nephritis because broad, rather than highly selective, effects are required to control the aberrant immune system. Nonetheless, these agents are not uniformly effective and are associated with substantial toxicities. The lack of universal efficacy raises the specter that lupus is a heterogeneous disorder with different etiopathogenesis in different subsets of patients (as in lupus-prone mice). Therapeutic prospects for the upcoming millennium include new forms and combinations of chemotherapeutic agents (mycophenolate and adenosine analogues), attempts to achieve immunological reconstitution using near-ablative chemotherapy (with or without bone marrow or stem cell rescue), monoclonal antibodies, and other inhibitors of T-cell costimulatory pathways (e.g., anti-CD154 and/or CTLA4-Ig). The prospect for gene therapy has already been realized in some animal models of SLE. In human SLE, the feasibility of gene therapy will depend on further definition of lupus-promoting genes and availability of methods to establish stable expression of potentially corrective genes.
Role of Caspase-8 Activation in Mediating Vitamin E-Induced Apoptosis in Murine Mammary Cancer Cells (2003)

The vitamin E family of compounds is divided into two subgroups, tocopherols and tocotrienols. However, tocotrienols display more potent apoptotic activity in mammary cancer cells. Although the mechanism(s) mediating tocotrienol-induced apoptosis is presently unknown, apoptosis is carried out by activation of initiator caspases (caspase-8 or -9) that subsequently activate effector caspases (caspase-3, -6, or -7). Studies were conducted to determine whether tocotrienol-induced apoptosis is mediated by activation of the caspase-8 and/or caspase-9 pathway. Highly malignant +SA mouse mammary epithelial cells were grown in culture and maintained on serum-free media. Treatment with tocotrienol-rich-fraction of palm oil (TRF) and g-tocotrienol, but not a-tocopherol, induced a dose-dependent decrease in +SA cell viability. TRF- and g-tocotrienol-induced cell death resulted from apoptosis, as determined by DNA fragmentation and positive TUNEL assay staining. Additional studies showed that treatment with 50 mM TRF or 20 mM g-tocotrienol increased intracellular activity and levels of processed caspase-8 and -3 but not caspase-9. Furthermore, treatment with specific caspase-8 or -3 inhibitors, but not caspase-9 inhibitor, completely blocked the tocotrienol-induced apoptosis in +SA cells. These findings demonstrate that tocotrienol-induced apoptosis in +SA mammary cancer cells is mediated through activation of the caspase-8 signaling pathway and is independent of caspase-9 activation.
Cloning of sucrase genes from<i>Streptococcus mutans</i>in bacteriophage lambda (1985)

Chromosomal DNA from Streptococcus mutans strain Ingbritt (serotype c) was cloned into the bacteriophage λ replacement vector L47.1. The bank of recombinant phage was screened for the presence of plaques in which sucrose-hydrolysing (sucrase) activity was expressed. Two distinct sucrase-expressing recombinants were identified. In one type, designated scr, the product is an invertase-like enzyme. This enzyme was purified from lysates of recombinants and shown to have an apparent Mr of 59000. The second class of recombinants was found to express a glucosyltransferase, identical in size, as well as in enzymatic and antigenic properties, to the previously described product of gtfA.
Role of Marine Natural Products in the Genesis of Antiviral Agents (2015)

ADVERTISEMENT RETURN TO ISSUEReviewNEXTRole of Marine Natural Products in the Genesis of Antiviral AgentsVedanjali Gogineni†, Raymond F. Schinazi‡, and Mark T. Hamann*†View Author Information† Department of Pharmacognosy, Pharmacology, Chemistry & Biochemistry, University of Mississippi, School of Pharmacy, University, Mississippi 38677, United States‡ Center for AIDS Research, Department of Pediatrics, Emory University/Veterans Affairs Medical Center, 1760 Haygood Drive NE, Atlanta, Georgia 30322, United States*E-Mail: [email protected]. Tel.: +1-662-915-5730. Fax: +1-662-915-6975.Cite this: Chem. Rev. 2015, 115, 18, 9655–9706Publication Date (Web):August 28, 2015Publication History Received2 November 2013Published online28 August 2015Published inissue 23 September 2015https://pubs.acs.org/doi/10.1021/cr4006318https://doi.org/10.1021/cr4006318review-articleACS PublicationsCopyright © 2015 American Chemical SocietyRequest reuse permissionsArticle Views5232Altmetric-Citations82LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:DNA replication,Genetics,Infectious diseases,Peptides and proteins,Viruses Get e-Alerts
Review: <i>The Foreign Policy of Thomas F. Bayard, 1885-1897</i>, by Charles Callan Tansill (1941)

Book Review| June 01 1941 Review: The Foreign Policy of Thomas F. Bayard, 1885-1897, by Charles Callan Tansill The Foreign Policy of Thomas F. Bayard, 1885-1897Charles Callan Tansill Charles H. Hunter Charles H. Hunter Search for other works by this author on: This Site PubMed Google Scholar Pacific Historical Review (1941) 10 (2): 238–239. https://doi.org/10.2307/3633654 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Charles H. Hunter; Review: The Foreign Policy of Thomas F. Bayard, 1885-1897, by Charles Callan Tansill. Pacific Historical Review 1 June 1941; 10 (2): 238–239. doi: https://doi.org/10.2307/3633654 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentPacific Historical Review Search This content is only available via PDF. Copyright 1941 The Pacific Coast Branch, American Historical Association Article PDF first page preview Close Modal You do not currently have access to this content.
Delay-Aware Data Delivery in Vehicular Intermittently Connected Networks (2013)

The open literature encloses numerous studies on the efficiency of retransmission mechanisms used in typical data communication networks for the purpose of recovering from packet transmission errors or losses. This paper revolves around the design and analysis of a Delay-Aware Data Delivery (DADD) scheme for Vehicular Intermittently Connected Networks (VICNs). At the heart of DADD is a novel mechanism that allows a source stationary roadside unit (SRU) to carry out necessary bundle retransmissions to high speed vehicles newly entering its communication range. In turn, these vehicles will guarantee delay-minimal delivery of the retransmitted bundles to the destination SRU. A mathematical model is developed to characterize the operation of the source SRU under DADD as well as to evaluate the resulting bundle delivery delay. To verify the validity and the accuracy of the proposed model, extensive simulations are conducted where the performance of DADD is compared to that of two other existing schemes. Results show that DADD outperforms these two schemes by 14.28% to 36.84%.
Computational analysis of coupled fluid-structure for a rotor blade in hover (2008)

로터 블레이드의 구조변형을 포함한, 제자리 비행하는 로터 블레이드의 공력해석을 수행하였다. 와류포획능력을 향상시킨 전산유체 코드와 간단한 오일러-베르누이 보 모델에 기반을 둔 구조역학 방정식을 결합시켜 회전익 유동에 대한 연계 계산을 수행하였으며 계산결과 타당한 로터블레이드 구조변형 및 공력특성을 얻었다. numerical study on the coupled fluid-structure for a rotor blade in hover was conducted. Computational fluid dynamics code with enhanced wake-capturing capability is coupled with a simple structural dynamics code based on Euler-Bernoulli's beam equation. The numerical results show a reasonable blade structural deformation and aerodynamic characteristics.
American Ginseng Berry Juice Intake Reduces Blood Glucose and Body Weight in <i>ob</i> / <i>ob</i> Mice (2007)

Diabetes is a serious chronic metabolic disease and has a significant impact on patients' lives and the health care system. We previously observed that the organic solvent extract of American ginseng berry possessed significant antidiabetic effects in obese diabetic ob/ob mice after intraperitoneal injection. If American ginseng berry is useful as a dietary supplement, simple preparation and oral intake would be a convenient, safe, and practical means for consumers. In this study, the simply prepared berry juice was first analyzed using high-performance liquid chromatography, and then administered orally in the ob/ob mice. The animals received daily berry juice 0.6 mL/kg or vehicle for 10 consecutive days. The results indicated that oral juice administration significantly lowered fasting blood glucose levels, and this effect continued for at least 10 d after cessation of the treatment. Data from intraperitoneal glucose tolerance test demonstrated that there was a notable improvement in glucose tolerance in the juice treated group. In addition, the berry juice significantly reduced body weight. Our data suggest that ginseng berry juice, as a dietary supplement, may have functional efficacy in consumers with diabetes.
Optical Constant Determination of Thin Polymer Films in the Infrared (1985)

Thin films of poly(vinyl chloride), poly(methyl methacrylate), and poly(styrene) were analyzed by Fourier transform infrared spectroscopy. The interference fringes present in the transmission spectra of these samples were used to determine film thickness and average refractive index. Subsequent Kramers-Kronig analysis of these transmission spectra provided the dispersion of the refractive index and the absorption index across the entire mid-infrared region. Interference fringes were absent in the optical constant spectra, and good agreement was obtained between our optical constant spectra and those of other authors.
Nox Reduction Catalysts for Vehicle Emission Control (1972)

<div class="htmlview paragraph">IIEC efforts to develop NO<sub>x</sub> catalysts with improved durability have continued. Properties of several nickel oxide catalysts on pelleted, monolithic ceramic, and metallic supports are discussed and the engineering requirements for their effective use are defined. Some promoted nickel oxide, pelleted catalysts show good low-temperature activity, and produce minimal amounts of ammonia but are strongly deactivated by sulfur in the feed gas. Monolithic and metallic catalysts, on the other hand, although not active at temperatures below 1000 F, are very active at higher temperatures where deactivation by sulfur and ammonia formation are not troublesome.</div>
THE OCCURRENCE OF A <i>FLAVOBACTERIUM</i> SPECIES IN CHILLED WATER (1950)

during the examination of chilled water from a churn immersion cooler it was observed that when the water was not changed at frequent intervals the colonies on standard nutrient agar incubated at 22° became entirely composed of a Flavobacterium sp. Colony counts greater than 10 6 /ml. were obtained at 3–5° and 22°. Although the dominant organism produced no visible change in litmus milk yet 0.1 ml. of chilled water clotted the milk within 48 hr. at 22°.
Direct Observation of Super‐Plasticity of Beta‐SiC Nanowires at Low Temperature (2007)

Abstract Super‐plasticity of single‐crystal beta‐SiC [111] nanowires for > 200 % elongation was observed by in situ axial‐tensile experiments in a scanning electron microscope. The SiC nanowires were characterized by a bamboo‐like structure appearing as the 3C structured segments intergrowth along the nanowire. The axial localized plasticity and super‐plasticity are suggested to result only from the 3C segments, through dislocation generation, propagation and amorphization in contrast to the highly defected structural segments that conduct elastic‐deformation only, owing to the lack of slip systems. These results provide key information for understanding the mechanical behavior of SiC nanowires.