gebhart/patrepeval huggingface dataset:
Point of care lung ultrasound in COVID-19: hype or hope? (2020)

The COVID-19 coronavirus pandemic has critically struck the world economy and healthcare systems. The highly contagious virus spreads rapidly and can result in potentially life-threatening acute respiratory distress. The current established test for diagnosing COVID-19 is using the RT-PCR laboratory test. However, the test requires specialized laboratories and testing kits. Recent reports also showed high false-negative rates. Experts recognize the urgent need to develop a rapid point of care diagnostic tests. Ultrasonography is a widely established safe diagnostic imaging test for detecting various lung abnormalities. Recent publications from China and Italy provided limited evidence on its usefulness for diagnosing COVID-19 in emergency departments earlier than RT-PCR. Ultrasound is sensitive to pleural and subpleural abnormalities, which suggests a great potential diagnostic role given the predilection for COVID-19 in peripheral subpleural regions.This paper reviews the current evidence and discusses the problems with specificity and scoring.
Clinical classification of perianal Crohn's disease (1992)

Assessment of the efficacy of therapeutic approaches to anal lesions of Crohn's disease is frustrated by the lack of precise definition of its various manifestations. A classification that is clinical and based on anatomic and pathologic aspects is presented; it has been derived from a 20-year prospective study of anal Crohn's disease in Cardiff. Conceptually, the classification is analogous to the TNM system for cancer. The main classification (U.F.S.) defines the presence of Ulceration, Fistula/abscess, and Stricture, qualified by numeric values reflecting severity (0 = not present, 1 = limited clinical impact, and 2 = severe). A subsidiary classification (A.P.D.) defines Associated conditions, Proximal intestinal involvement, and Disease activity. In addition, the classification may be used in a detailed form for research or comparative purposes or in a simple form defining only the dominant lesions for routine clinical use. General use of the classification would make it possible to compare in detail incidence, management, and results of treatment in different centers.
The FUBI system for solar rating nonprescription eyewear. (2002)

The FUBI system presents a comprehensive, scientifically valid means of rating nonprescription eyewear for solar protective value. The system will provide consumers of nonprescription eyewear with more useful, comparative information about the protective qualities of eyewear against solar radiation.
Frequency tunable silicon carbide resonators for MEMS above IC (2008)

Micro-electromechanical beam resonators and arrays are fabricated using a custom low-temperature (< 300degC) CMOS-compatible silicon carbide micro-fabrication process. A special feature of this process is that it allows the integration of heaters directly onto the MEMS devices, thus enabling resonant frequency tuning with constant insertion loss and considerable extension of the tuning range. Characteristics for different devices are measured with quality factors of Q ap 1000 and resonant frequencies of up to 21.8 MHz.
The detection of verocytotoxins in bacterial cultures from human diarrhoeal samples with monoclonal antibody-based ELISAs (1996)

Bacterial cultures from 1801 human diarrhoeal faecal specimens were examined for verocytotoxins I and II by monoclonal antibody-based sandwich ELISAs. Of the 68 ELISA-positive cultures selected from initial screening, 32 were positive by ELISA on repeat or from freshly grown cultures. ELISA-positive pure cultures were obtained from 13 of these, of which seven were confirmed as verocytotoxin positive by cytotoxicity assay. These seven strains were typed as O26 (5) and O146 (2). The six false positive results were from isolates of Enterobacter sp. (1), Citrobacter Freundii (1) and Escherichia coli (4), one each of types O1, O18ac and O98 and an untypable strain. Despite the occurrence of false positive reactions, sandwich ELISA was a useful method for the rapid screening of samples, and detected verocytotoxin-positive E. coli strains, other than O157, from patients with clinical conditions in which they could be implicated.
Implementation and analysis of path history in dynamic branch prediction schemes (1998)

Accurate branch prediction is essential for providing higher performance levels in modern processors. Many branch predictors use branch execution history to identify repetitive branch behavior. Path history provides additional information that may help separate sequences of different branch instructions with identical execution history. We present a method to implement path history in hardware-based branch prediction, and a comprehensive simulation study of branch prediction strategies that integrate path history.
A cyclin-dependent kinase homologue, p130PITSLRE is a phosphotyrosine-independent SH2 ligand (1994)

Src-homology 2 (SH2) domains are conserved, globular protein modules that mediate assembly of multicomponent signaling complexes. Phosphoproteins from the B-lymphoid cell line A20 were isolated by SH2 affinity chromatography; the peptide sequence from one of these proteins was used to molecularly clone several related complementary DNAs whose predominant protein product, p130PITSLRE, is an abundant serine/threonine kinase with ubiquitous expression in murine tissues. The sequence of a previously described cyclin-dependent kinase homologue, p58clk-1, is entirely contained within the p130PITSLRE sequence. Specific binding of p130PITSLRE to SH2 domains is mediated by a serine- and glutamic acid-rich cluster of amino acids in the N-terminal region. This interaction is dependent on serine/threonine phosphorylation but independent of tyrosine phosphorylation. Binding is inhibited by free phosphotyrosine and by a phosphotyrosine-containing peptide from polyoma middle T antigen, suggesting that the p130PITSLRE binding site in the SH2 domain overlaps the region that binds phosphotyrosine-containing peptides. Bacterially expressed p130PITSLRE fragments acquire the ability to bind an SH2 domain when phosphorylated in vitro with casein kinase II. A subset of casein kinase II phosphorylation sites may therefore constitute a phosphotyrosine-independent class of SH2 ligands.
Garlic as a Lipid Lowering Agent—A Meta-Analysis (1994)

Garlic supplements may have an important role to play in the treatment of hypercholesterolaemia. To determine the effect of garlic on serum lipids and lipoproteins relative to placebo and other lipid lowering agents, a systematic review, including meta-analysis, was undertaken of published and unpublished randomised controlled trials of garlic preparations of at least four weeks' duration. Studies were identified by a search of MEDLINE and the ALTERNATIVE MEDICINE electronic databases, from references listed in primary and review articles, and through direct contact with garlic manufacturers. Sixteen trials, with data from 952 subjects, were included in the analyses. Many of the trials had methodological shortcomings. The pooled mean difference in the absolute change (from baseline to final measurement in mmol/l) of total serum cholesterol, triglycerides, and high-density lipoprotein (HDL)-cholesterol was compared between subjects treated with garlic therapy against those treated with placebo or other agents. The mean difference in reduction of total cholesterol between garlic-treated subjects and those receiving placebo (or avoiding garlic in their diet) was -0.77 mmol/l (95% CI: -0.65, -0.89 mmol/l). These changes represent a 12% reduction with garlic therapy beyond the final levels achieved with placebo alone. The reduction was evident after one month of therapy and persisted for at least six months. In the dried garlic powders, in which the allicin content is standardised, there was no significant difference in the size of the reduction across the dose range of 600-900 mg daily. Dried garlic powder preparations also significantly lowered serum triglyceride by 0.31 mmol/l compared to placebo (95% CI: -0.14, -0.49).(ABSTRACT TRUNCATED AT 250 WORDS)
New laser-matter interaction concept to enhance hard tissue cutting efficiency (1994)

Human enamel and dentin were cut using a 2.8 micrometers erbium laser beam in conjunction with water spray. Ablation rates of the order of 0.14 mm<SUP>3</SUP>/s were achieved for both tissues at 4 W average power. An ablation threshold of 0.28 W was determined for dentin when using the water spray. When above threshold, the volume of tissue ablated per joule was discovered to be nearly constant, not related to the average laser power. Comparative microscopy between tissue irradiated with and without water spray demonstrated a lack of thermal effects when the water spray was utilized.
Two-dimensional block diagonal LMS adaptive filtering (1994)

The paper is concerned with the development of two-dimensional (2D) adaptive filters using the block diagonal least mean squared (BDLMS) method. In this adaptive filtering scheme, the image is scanned and processed block by block in a diagonal fashion, and the filter weights are adjusted once per block rather than once per pixel. The diagonal scanning is adopted to avoid the problems inherent in the 1D standard scanning schemes and to account for the correlations in two directions. The weight updating equation for 2D BDLMS is derived, and the convergence properties of the algorithms are investigated. Simulation results that indicate the effectiveness of the 2D BDLMS when used for image enhancement, estimation, and detection applications are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Additive-induced miscibility regulation and hierarchical morphology enable 17.5% binary organic solar cells (2021)

Herein, a facile and effective strategy is demonstrated to unleash the full potential of existing photoactive materials.
Virtual reality control of a robotic camera holder for minimally invasive surgery (2017)

This paper presents a virtual reality(VR) control system for a robotic endoscope holder for minimally invasive surgery (MIS). The system features a three degree of freedom(DOF) robotic endoscope holder, virtual reality head mounted display and a control system that allows robot to follow headset movement. The headset display is aligned with endoscope camera view thus creating a full presence effect for a surgeon. The video from endoscope is streamed to the virtual reality head mounted display after image processing in a computer. During surgery, the proposed control system generates commands to the robot based on the headset's positioning data. After the desired camera motion direction is estimated, the robotic endoscope holder receives motion commands through serial interface. The proposed virtual reality robot control system is implemented in Unity. The system has been tested in the laboratory environment through a set of motion tests and achieved a response latency of 2s. The proposed system is able to restore the surgeon's perceptual capability of the operation space that is highly restricted in MIS and provide highly intuitive endoscope robot control.
Gastric perforation associated with indomethacin therapy in a pre‐term infant. (1980)

ABSTRACT. This is a case report of a pre‐term infant who developed a gastric perforation fifteen hours after receiving oral indomethacin treatment for the pharmacological closure of a patent ductus arteriosus. This observation of a possible causal relationship between indomethacin and gastric perforation reaffirms the need for caution when using this drug in pre‐term infants.
Studies of MHD Propulsion for Underwater Vehicles and Seawater Conductivity Enhancement (1991)

This study analyzes the feasibility of MHD propulsion for marine vessels. A theoretical analysis is developed and analytical results are obtained for two vehicle geometries. The first (class 1) is for small vehicles with sizes approximating that of torpedos, remotely operated vehicles (ROV), and underwater autonomous vehicles (UAV). The second geometry (class 2) corresponds to larger submersibles such as submarines. Vehicle speed, thrust, and efficiency are analyzed as a function of magnetic field strength and channel velocity. Results indicate that thruster performance measures as the square of an increasing magnetic field strength and linearly with increasing conductivity. The analytical results show that the MHD thruster tends to favor larger geometries and channel lengths, such as those applicable to class 2 vehicles. Based on analytical parametric studies, the MHD thruster propelled large submersible can attain comparable velocities to that of present day submarines (20-42 knots). Additionally, the MHD thruster concept offers potentially easier maintenance because of no moving parts and thereby reduced vessel detectability. Higher speeds then attained by present submersibles may be possible due to reduced hydrodynamic drag.
Cross-species bone marrow transplantation: evidence for tolerance induction, stem cell engraftment, and maturation of T lymphocytes in a xenogeneic stromal environment (rat----mouse). (1991)

Transplantation of untreated F344 rat bone marrow into irradiated B10 mouse recipients (non-TCD F344----B10) to produce fully xenogeneic chimeras resulted in stable xenogeneic lymphoid chimerism, ranging from 82% to 97% rat. Survival of animals was excellent, without evidence for GVH disease. The specificity of tolerance which resulted was highly donor-specific; MHC disparate third party mouse and rat skin grafts were promptly rejected while donor-specific F344 grafts were significantly prolonged (MST greater than 130 days). Multi-lineage rat stem cell-derived progeny including lymphoid cells (T- and B-lymphocytes), myeloid cells, erythrocytes, platelets, and natural killer (NK) cells were present in the fully xenogenic chimeras up to 7 months after bone marrow transplantation. Immature rat T-lymphocytes matured and acquired the alpha/beta T-cell receptor in the thymus of chimeras in a pattern similar to normal rat controls, suggesting that immature T-lymphocytes of rat origin could interact with the murine xenogeneic thymic stroma to undergo normal maturation and differentiation. This model may be useful to study the mechanisms responsible for the induction and maintenance of donor-specific transplantation tolerance across a species barrier.
The Netrin-1/DCC guidance system: dopamine pathway maturation and psychiatric disorders emerging in adolescence (2019)

Axon guidance molecules direct growing axons toward their targets, assembling the intricate wiring of the nervous system. One of these molecules, Netrin-1, and its receptor, DCC (deleted in colorectal cancer), has profound effects, in laboratory animals, on the adolescent expansion of mesocorticolimbic pathways, particularly dopamine. Now, a rapidly growing literature suggests that (1) these same alterations could occur in humans, and (2) genetic variants in Netrin-1 and DCC are associated with depression, schizophrenia, and substance use. Together, these findings provide compelling evidence that Netrin-1 and DCC influence mesocorticolimbic-related psychopathological states that emerge during adolescence.
Microarray Approaches to Gene Expression Analysis (2006)

1.1. Background And Overview A powerful suite of new technologies now makes it possible to measure simultaneously the expression of many thousands of genes directly from a clinical sample (1). Known alternately as DNA microarrays, gene arrays, expression arrays, “pgene chips,” or various permutations thereof, technologies for measuring gene expression are already beginning to have many applications in clinical diagnosis. The most promising to date are in cancer diagnosis, where microarray classification has suggested clinically meaningful distinctions that are difficult or impossible to make by conventional histopathology alone (2,3).As the experimental and analytical techniques have developed, applications have been suggested across the spectrum of human pathology, including infectious, vascular, genetic, inflammatory, psychiatric, and metabolic diseases.
Application of extended Kalman filter techniques for dynamic model parameter calibration (2009)

Phasor measurement has previously been used for sub-system model validation, which enables rigorous comparison of model simulation and recorded dynamics and facilitates identification of problematic model components. Recent work extends the sub-system model validation approach with a focus on how model parameters may be calibrated to match recorded dynamics. In this paper, a calibration method using Extended Kalman Filter (EKF) technique is proposed. This paper presents the formulation as well as case studies to show the validity of the EKF-based parameter calibration method. The proposed calibration method is expected to be a cost-effective means complementary to traditional equipment testing for improving dynamic model quality.
Sarcopenia in patients with bladder cancer undergoing radical cystectomy: Impact on cancer‐specific and all‐cause mortality (2014)

The presence of sarcopenia was found to significantly increase a patient's risk of CSS and all-cause mortality after undergoing RC for bladder cancer.
Armored phased array design (1993)

The Georgia Tech Research Institute (GTRI) has performed modeling, analysis, and testing of array face armoring as a survivability enhancement feature for a forward acquisition radar. This paper describes array face armoring technology developed by GTRI, including: (1) materials testing, (2) array element design, (3) waveguide simulator tests, and (4) armor mounting options. Results show that the array face can be protected against the simulated tactical threat while achieving acceptable electrical performance. The armoring consists of a layer of Spectra Shield (a proprietary material) approximately 2.54 cm thick covering the face of the array. It is noted that the array face armoring must be developed from the point of view of integrating the armor with the aperture/element design rather than designing the aperture then adding the armor.
Oxide field and thickness dependence of trap generation in 9–30 nm dry and dry/wet/dry oxides (1991)

The oxide electric field and thickness dependencies of the oxide electron trap generation rate measured on 86–315 Å thick 900 °C dry oxide and 850 °C dry/wet/dry oxide stressed by substrate electron injection at average dc oxide fields of 1–9 MV/cm are reported. A minimum in the steady-state gate voltage shift versus oxide electric field is discovered which suggests a balance of the field-dependent electron trap charging and discharging rates with the generation rate of oxide traps by oxide field-accelerated hot electrons. The thickness and field dependencies of trap charging, discharging, and generation are compared for two industrial oxidation processes, 900 °C dry and 850 °C dry/wet/dry oxides, and are shown to have similar trap generation rates. A new two-trap generation-charging-discharging model is proposed and shown to give excellent agreement with the experimental data.
In utero repair of myelomeningocele (2003)

Fetoscopic repair, although feasible, does not yet yield optimal surgical results. Open surgical repair before 22 weeks' gestation is physiologically sound and technically feasible. One third of patients appear to be spared the need for a shunt at age 1 year, but improvement in distal neurologic function is less clear. Additionally, fetal mortality is associated with this procedure. Our results complement the data published by groups at Children's Hospital of Philadelphia, in Pennsylvania, and Vanderbilt University, Nashville, Tenn. A National Institutes of Health-sponsored prospective randomized trial is now underway at these 3 centers to compare fetal repair with postnatal repair.
Resveratrol induced apoptosis and cell arrest in cancer cells (2005)

AIM: To study the mechanism of resveratrol induced HepG2 and K562 cells apoptosis and cell arrest. METHODS: Cell morphological method and Annexin V technology were used to detect HepG2 and K562 cells apoptosis, flow cytometry (FCM) was used to detect the cell cycle and MTT was used to detect the medicine sensitivity of HepG2 and K562 cells. RESULTS: Apoptosis was seen in human liver cancer HepG2 cell treated with resveratrol and nuclear chromatine condensation and fragmentation were observed in HepG2 cells. Typical ladder patterns of DNA fragmentation were also observed. The highest rate of HepG2 cell apoptosis was 33.7% by Annexin V. Cell cycle stopped at S phase and cell apoptosis rate was 9.97% by FCM. Time and dose dependent effects of resveratrol to HepG2 cell were detected by MTT. Resveratrol had no effect on K562 cells. CONCLUSION: Resveratrol induces HepG2 cell apoptosis and inhibits the development of human liver cancer with a time and dose dependent effect. The resveratrol-induced cell apoptosis is specific to cancer cells.
Simultaneous Phenotyping of ACP1, ADA and PGM1 byIsoelectric Focusing (1987)

A simple, fast and reliable isoelectric focusing method for the simultaneous determination of ACP1, ADA and PGM1 is presented, which provides a useful tool for the further study of anthropological and forensic haemogenetics.
Design and Development of Weapons and Equipment Manage System Based on RFID Technology (2011)

This article describes the radio frequency identification (RFID) technology and features, and designs of weapons and equipment of a RFID application management system, indicating the overall weapons and equipment management system software and hardware architecture of the system architecture system and the principle of weapons and equipment management system Database design and security of the system to make reasonable suggestions. The entire system through the use of radio frequency identification technology to change the original weapons and equipment to rely on manual data collection the way, exclude the interference of human factors, not only improves the accuracy of monitoring, monitoring of real-time alarm, but also reduce the monitoring cost, easy to manage.
Functional properties of acid and salt extracted proteins of yellow peas (Pisum sativum L. Miranda) (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFunctional properties of acid and salt extracted proteins of yellow peas (Pisum sativum L. Miranda)Uken S. S. Soetrisno and ZoeAnn. HolmesCite this: J. Agric. Food Chem. 1992, 40, 6, 975–980Publication Date (Print):June 1, 1992Publication History Published online1 May 2002Published inissue 1 June 1992https://doi.org/10.1021/jf00018a012RIGHTS & PERMISSIONSArticle Views164Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (613 KB) Get e-Alertsclose Get e-Alerts