gebhart/patrepeval huggingface dataset:
Crystal Phases in the System Al <sub>2</sub> O <sub>3</sub> –AlN (1961)

Fused aluminum oxide containing a small amount of nitrogen (as added aluminum nitride) showed X‐ray powder diffraction patterns similar to the δ‐alumina obtained from the calcination of alumina mouohydrate in dry air. About 1% nitrogen was adequate for complete conversion of the α phase to the δ phase. A fused mixture containing 3.9% nitrogen showed a powder pattern identical to lithium ζ‐alumina.
REVIEWS (1981)

Journal Article REVIEWS Get access The Gnostic Treatise on Resurrection from Nag Hammadi. By BENTLEY LAYTON. Pp. x+220. (Harvard Theological Review: Harvard Dissertations in Religion, 12.) Missoula, Montana: Scholars Press, 1979. $7.50. K. H. KUHN K. H. KUHN Search for other works by this author on: Oxford Academic Google Scholar The Journal of Theological Studies, Volume XXXII, Issue 1, April 1981, Pages 266–268, https://doi.org/10.1093/jts/XXXII.1.266 Published: 01 April 1981
<i>Blakeslea trispora</i> Genes for Carotene Biosynthesis (2004)

We cloned the carB and carRA genes involved in beta-carotene biosynthesis from overproducing and wild-type strains of Blakeslea trispora. The carB gene has a length of 1,955 bp, including two introns of 141 and 68 bp, and encodes a protein of 66.4 kDa with phytoene dehydrogenase activity. The carRA gene contains 1,894 bp, with a single intron of 70 bp, and encodes a protein of 69.6 kDa with separate domains for lycopene cyclase and phytoene synthase. The estimated transcript sizes for carB and carRA were 1.8 and 1.9 kb, respectively. CarB from the beta-carotene-overproducing strain B. trispora F-744 had an S528R mutation and a TAG instead of a TAA stop codon. The overproducing strain also had a P143S mutation in CarRA. Both B. trispora genes could complement mutations in orthologous genes in Mucor circinelloides and could be used to construct transformed strains of M. circinelloides that produced higher levels of beta-carotene than did the nontransformed parent. The results show that these genes are conserved across the zygomycetes and that the B. trispora carB and carRA genes are functional and potentially useable to increase carotenoid production.
Electrochemical Therapy to Treat Cancer (In Vivo Treatment) (2007)

The aim of this paper is to present the evaluations and results attained by our research group from the clinical applications of Electrochemical Therapy (EChT in short) on tumors, specifically of cats and dogs. Our in vivo results indicate that EChT is an effective cancer treatment. Application of EChT in human beings was approved by National Health Surveillance Agency, which is linked to the Brazilian Ministry of Health. To make EChT available for cancer patients in the Brazil, basic studies were conducted and a Phase I clinical trial was started.
SANG : the horn of the National Art Museum's dilemma post-1994 South Africa : Session 1 : governance and good practice (2004)

I have told the story of a process of transformation that was initiated at the South African National Gallery (SANG) in 1990 many times. The catalogue Contemporary South African Art 1985-1995 from the South African National Gallery Permanent Collection reflects how the change in government and the new policies generated by the Department of Arts, Culture, Science and Technology (DACST) impacted on the composition of the Board of Trustees and the working committees of the Board. There was a sense of renewal and enthusiasm as we looked forward to a new era in which there would be interest in and support for our national museums.
Anaerobic digestion of cellulose fraction of domestic refuse by means of rumen microorganisms (1988)

The anaerobic digestion of a cellulose-enriched fraction of domestic refuse by means of rumen microorganisms in an "artificial rumen" digester was studied. Various combinations of solid and liquid retention times and loading rates were applied to establish optimum conditions for the acidogenic phase digestion of the refuse fraction. An optimal substrate conversion of about 72% was obtained at a loading rate of 23.4 g volatile solids (VS)/L d and a solids retention time of 90 h. Variation of dilution rate between 1.04 and 3.14 fermentor volume turnovers per day had no effect on degradation efficiency. At a loading rate of 23.4 g VS/L d a differential removal rate of solids and liquids appeared to be necessary to obtain an effective degradation of the refuse fraction.
Surface Hardness of Pristine and Modified Polyaniline Films (1999)

The surface microhardness of conventional thermoplastics lie between 0.1 and 0.6 GPa. The as-cast emeraldine (EM-25) base film of polyaniline (PANi) exhibits a surface microhardness of about 1 GPa. The hardness is increased to about 4 GPa in the highly cross-linked EM (EM-150) film. This hardness value is further enhanced to about 6 GPa after 1 cycle of acid−base treatment. The hardness of the EM-150 film can also be enhanced to about 8 GPa through protonation or through reduction to the leucoemeraldine state. Surface modification of the EM-150 films via graft copolymerization with acrylic acid or styrenesulfonic acid readily gives rise to hard-surfaced PANi films having microhardness values approaching 20 GPa. This surface hardness is comparable to many of those reported for the very hard-surfaced conventional polymers from high-energy ion-beam bombardments. The surface hardness of the surface-modified EM-150 film arises from the additional covalent bonding of the graft chains on the highly cross-linked EM-150 film surface and the charge-transfer interaction between the graft and the substrate chains.
Bosentan, a new endothelin receptor antagonist: prediction of the systemic plasma clearance in man from combined in vivo and in vitro data (1995)

1. Accurately predicting the kinetics in man greatly improves the design of the phase I clinical studies. This was particularly crucial in the case of bosentan, a new endothelin receptor antagonist, as very large interspecies differences in systemic clearance were observed in the animal species investigated, namely from 1.5ml/min/kg in the dog up to 70 ml/min/kg for the rabbit. 2. Bosentan was shown to be metabolized by the hepatic cytochrome P450, therefore the rate of metabolism was investigated in vitro in liver microsomes and hepatocytes, across the species which had been tested in vivo. The same rank-order of metabolism was found for the laboratory animals both in vitro and in vivo, and hepatocytes appeared to be more representative of the in vivo situation than liver microsomes. The in vitro clearance in human hepatocytes was very close to that observed in dog hepatocytes. 3. A plasma clearance for bosentan in man of 1-2 ml/min/kg was predicted by combining the in vivo and in vitro data from a few animal species with the in vitro data in man. This expectation was subsequently found to agree reasonably well with the plasma clearance observed in healthy volunteers: ca 2 ml/min/kg. Integrating this prediction into the design of the first clinical protocols substantially improved the quality of the human pharmacokinetic data obtained.
Nickel-Catalyzed Cross-Coupling Reaction of Aryl Halides in Pyridine. A Practical Synthesis of 4′-Methylbiphenyl-2-carbonitrile As a Key Intermediate of Angiotensine II Receptor Antagonists (1994)

The title reaction was found to afford unsymmetrical biphenyl derivatives little less than 70% selectivity, which was strongly depended on the aryl halides employed. 4′-Methyl-1,1′-biphenyl-2-carbonitrile was isolated in 59% yield as a pure state by a simple crosscoupling reaction of 4-bromotoluene and 2-chlorobenzonitrile.
Pond: the oceanstore prototype (2003)

OceanStore is an Internet-scale, persistent data store designed for incremental scalability, secure sharing, and long-term durability. Pond is the OceanStore prototype; it contains many of the features of a complete system including location-independent routing, Byzantine update commitment, push-based update of cached copies through an overlay multicast network, and continuous archiving to erasure-coded form. In the wide area, Pond outperforms NFS by up to a factor of 4.6 on readintensive phases of the Andrew benchmark, but underperforms NFS by as much as a factor of 7.3 on write-intensive phases. Microbenchmarks show that write performance is limited by the speed of erasure coding and threshold signature generation, two important areas of future research. Further microbenchmarks show that Pond manages replica consistency in a bandwidthefficient manner and quantify the latency cost imposed by this bandwidth savings.
Ferritin: design and formation of an iron-storage molecule (1984)

Although essential for most forms of life, too much iron is harmful. To cope with these antagonistic phenomena an iron-storage molecule, ferritin, has evolved. The structure of horse spleen apoferritin, which has recently been refined, consists of 24 symmetrically related subunits forming a near-spherical hollow shell. In ferritin the central cavity is occupied by an iron core of 'ferrihydrite', a geologically ephemeral mineral found in hot or cold springs and in mine workings, or produced in the laboratory by heating solutions of ferric salts. Ferritin itself forms most readily from apoferritin, in the presence of dioxygen, from FeII, not FeIII. Access to its interior is through small intersubunit channels, and the protein influences both the rate of FeII-oxidation and the form of oxide produced.
Zur Synthese des C<sub>25</sub>‐Alkohols Moenocinol Fragmentierungsversuche an cyclischen β‐Ketotosylaten und β‐Hydroxytosylaten (1985)

Abstract Die als Zwischenprodukte im Rahmen einer Moenocinol‐Synthese vorgesehenen Verbindungen 15 und 16 konnten durch Grob‐Fragmentierung aus 14 bzw. 17 nicht erhalten werden. Stattdessen reagierte 17 mit Natriummethanolat zu 34, 36 und 38 , und aus 14 entstand unter Baseneinwirkung das Oxetan 43 . Die Modellverbindungen 27 und 30 gingen die erwünschte Fragmentierungsreaktion ein. Außerdem wird die Spaltung des Oxetans 32 mit Zirconocen beschrieben.
The Convergence of a Class of Double-rank Minimization Algorithms (1970)

This paper presents a new minimization algorithm and discusses theoretically some of its properties when applied to quadratic functions. Results of comparative testing for a set of non-quadratic functions are described and reasons for the observed experimental behaviour are suggested.
Selection and Application of Tissue microRNAs for Nonendoscopic Diagnosis of Barrett’s Esophagus (2018)

In analyses of miRNA expression patterns of BE vs non-BE tissues, we identified a profile that can identify Cytosponge samples from patients with BE with an AUC of 0.93. Expression of MIR194 is increased in BE samples via epigenetic mechanisms that might be involved in BE pathogenesis.
LiVP[sub 2]O[sub 7]: A Viable Lithium-Ion Cathode Material? (2005)

The preliminary performance characteristics of a lithium-ion cell are described. The diphosphate active material was prepared using a carbothermal reduction approach. Contrary to previous reports, we found that the cathode shows encouraging electrochemical performance characterized by good material utilization and low voltage polarization. A cathode specific capacity approaching was recorded under low rate conditions. In addition, preliminary constant current testing at and indicates that the system cycles with relatively low capacity fade characteristics. The diphosphate based lithium-ion cell may be suitable for some low rate applications.
Isolation of a Candida albicans mutant with reduced content of cell wall mannan and deficient mannan phosphorylation. (1984)

A rough-colony mutant of Candida albicans was isolated after ultraviolet mutagenesis. The mutant contained approximately half the normal amount of the cell wall mannan, the acetolysis pattern of which was indistinguishable from that of the wild-type counterpart. However, the extent of phosphorylation in the mutant mannan was about 12% of the value for wild type.
Calibration of Quantitative Echo Sounders by Using Echo from Water Tank Surface. (1997)

In order to get reliable results from surveys by quantitative echo sounders, an accurate calibration of the sounder is necessary especially for the transmitting and receiving system. Therefore, we investigated a new method of simple and accurate calibration by utilizing the echoes from the water surface of an experimental water tank. We show that the method can easily calibrate the equivalent beam width of surface scattering by application of the property that the backscattering strength of the surface of water is 0dB. In case of a sharp beam, we show that the equivalent beam widths for surface scattering and volume scattering are nearly the same. Moreover, it is possible to perform an overall calibration of the transmitting and receiving system, including the equivalent beam width and the transmitting and receiving sensitivities, thus producing a more reliable result than the method in which each factor is measured separately.
Bond Strength of Resin Cements to a Zirconia Ceramic with Different Surface Treatments (2009)

This study evaluated the influence of surface treatments and metal primers on the bond strength of resin cements to a yttrium-stabilized tetragonal zirconia (Y-TZP) ceramic. Two-hundred and forty plates of Y-TZP ceramic were randomly assigned to 24 groups (n = 10) according to the combination of surface treatment (none, air abrasion with Al2O3 particles, Er:YAG laser irradiation), metal primer (none, Alloy Primer, Metal Primer II or Metaltite) and resin cement (Calibra [Bis-GMA-based] or Panavia F2.0 [MDP-based]). Fragments of dentin with a cylindrical edge (0.8 mm in diameter) were fixed to ceramic surfaces with the resin cements. The micro-shear bond test was carried out at a 1 mm/minute speed until failure, and the ceramic surfaces were examined after debonding. Bond strengths were analyzed through three-way ANOVA/Tukey test with a 5% significance level. Changes in topography after surface treatments were evaluated with scanning electron microscopy. Surface treatments significantly modified the topography of the Y-TZP ceramic. Air abrasion resulted in increased bond strength for both resin cements. However, air abraded and laser irradiated specimens presented higher bond strength with the Bis-GMA-based resin cement than with the MDP-based cement. Both cements presented similar behavior on untreated surfaces. The three metal primers yielded a significant increase in bond strength, regardless of the surface treatment and resin cement. Adhesive failures were the most prevalent. Air abrasion with Al2O3 particles and the application of metal primers increased bond strength to Y-TZP surfaces for both resin cements.
Quantitative Studies on Lithium Aluminum Hydride Reactions (1949)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTQuantitative Studies on Lithium Aluminum Hydride ReactionsF. A. HochsteinCite this: J. Am. Chem. Soc. 1949, 71, 1, 305–307Publication Date (Print):January 1, 1949Publication History Published online1 May 2002Published inissue 1 January 1949https://pubs.acs.org/doi/10.1021/ja01169a082https://doi.org/10.1021/ja01169a082research-articleACS PublicationsRequest reuse permissionsArticle Views463Altmetric-Citations49LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Hypoxic-Ischemic Oligodendroglial Injury in Neonatal Rat Brain (2002)

Neonatal periventricular white matter injury is a major contributor to chronic neurologic dysfunction. In a neonatal rat stroke model, myelin basic protein (MBP) immunostaining reveals acute periventricular white matter injury. Yet, the extent to which myelin proteins can recover after neonatal hypoxic-ischemic injury is unknown. We developed a quantitative method to correlate the severity of the hypoxic-ischemic insult with the magnitude of loss of MBP immunostaining. Seven-day-old (P7) rats underwent right carotid ligation, followed by exposure to 8% oxygen for 1, 1.5, 2, or 2.5 h. On both P12 and P21, white matter integrity was evaluated by densitometric analysis of MBP immunostaining, and the amount of tissue injury was evaluated by morphometric measurements of cerebral hemisphere areas. The most severe hypoxic-ischemic insults (2.5 h) elicited marked reductions in MBP immunostaining ipsilaterally on both P12 and P21. In contrast, in mildly lesioned animals (1.5 h), MBP immunostaining was reduced ipsilaterally on P12, but 2 wk after lesioning, on P21, there was a substantial restoration of MBP immunostaining. The restoration in MBP immunostaining could reflect either functional recovery of injured oligodendroglia or proliferation and maturation of oligodendroglial precursors. Our data demonstrate that quantitative measurement of MBP immunostaining provides a sensitive indicator of acute oligodendroglial injury. Most importantly, we show that in this neonatal rodent stroke model, restoration of myelin proteins occurs after moderate, but not after more severe, cerebral hypoxia-ischemia.
Preparation of <sup>14</sup>C‐ and <sup>3</sup>H‐methoxyl‐labelled forms of ubiquinone by photochemical <i>O</i>‐demethylation and subsequent remethylation (1970)

Abstract Ubiquinone [ubiquinone (50), coenzyme Q 10 , CoQ 10 ] undergoes O‐demethylation to the 2‐ and 3‐hydroxyubiquinones, reduction to the hydroubiquinone, and cyclization to the ubichromenol derivative when irradiated, in alcohol solution, with a sunlamp. It is likely that the ubichromenol and hydroubiquinone derivatives form via a common intermediate which is different from that involved in the formation of the hydroxyubiquinone derivatives. The mixture of hydroxyubiquinones, on methylation with 14 C‐ and 3 H‐labelled methyl iodide or diazomethane, yields methoxyl‐labelled ubiquinone, a material useful in the study of ubiquinone photodecomposition, metabolism, and biochemistry.
Designing IoT architecture(s): A European perspective (2014)

Internet of Things (IoT) domain has attracted a lot of interest over the last few years, to a large extent due to its applicability across a plethora of application domains. This variety of application domains resulted in a variety of requirements that IoT systems should comply with. Due to the heterogeneity of the domains, the requirements varied significantly, and demanding more or less complex systems with varied performance expectations. This situation affected the architecture design and resulted in a range of IoT architectures with not only varied set of components and functionalities, but also varied terminologies used. It resulted in limited interoperability between the systems which in turn hampered development of the complete domain. To address these issues, to ensure a common understanding by providing a framework catering for different applications and eventually enable reuse of the existing work across the domains, reference architectures are an appropriate tool. This paper presents an overview of the activities done in Europe towards definition of such a common framework together with how it is being used and a potential outlook for these efforts.
Hypoglycemic activity of aldose reductase inhibitor, 1-((p-bromophenyl)sulfonyl)hydantoin. (1984)

The hypoglycemic activity of a potent aldose reductase inhibitor, 1-[(p-bromophenyl)-sulfonyl] hydantoin (p-Br-PSH), was tested. The compound was not effective when orally administered to rabbits at a dose of 25 mg/kg, whereas statistically significant hypoglycemic activity was observed at doses of 50 and 100 mg/kg. The hypoglycemic activity of p-Br-PSH, however, was lower than that of tolbutamide.
Determining the Absolute Requirement of G Protein–Coupled Receptor Kinase 5 for Pathological Cardiac Hypertrophy (2012)

These results define myocyte GRK5 as a critical regulator of pathological cardiac growth after ventricular pressure overload, supporting its role as an endogenous (patho)-physiological HDAC kinase. Further, these results define GRK5 as a potential therapeutic target to limit HF development after hypertrophic stress.
NF-κB Activation in Esophageal Adenocarcinoma (2004)

Bile acids and low pH induce NF-kappaB expression in esophageal cell lines. NF-kappaB activation is common in esophageal adenocarcinoma. In patients with Barrett's epithelium and an associated esophageal adenocarcinoma, there is a progressive expression of NF-kappaB through Barrett's tumorigenesis. The absence of NF-kappaB expression in esophageal adenocarcinoma correlates with response to neoadjuvant chemoradiotherapy and may be of value in predicting response to neoadjuvant therapy.
Antiviral agents. 1. Benzothiazole and benzoxazole analogs of 2-(.alpha.-hydroxybenzyl)benzimidazole (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAntiviral agents. 1. Benzothiazole and benzoxazole analogs of 2-(.alpha.-hydroxybenzyl)benzimidazoleW. A. Skinner, F. Gualtiere, G. Brody, and A. H. FieldsteelCite this: J. Med. Chem. 1971, 14, 6, 546–549Publication Date (Print):June 1, 1971Publication History Published online1 May 2002Published inissue 1 June 1971https://pubs.acs.org/doi/10.1021/jm00288a022https://doi.org/10.1021/jm00288a022research-articleACS PublicationsRequest reuse permissionsArticle Views404Altmetric-Citations29LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts