gebhart/patrepeval huggingface dataset:
Validation of a Mobile Application Water Planning Tool for Road Race Event Organizers (2018)

The results of the RRWP analysis indicate that it can provide event organizers with a valid, quantitative way to narrow the uncertainties of water planning related to changes in participant numbers, race distance, and weather. "Rule of thumb" alternatives are also discussed.
Mycobactericidal Activity of Human Natural, Monoclonal, and Recombinant Yeast Killer Toxin‐like Antibodies (1998)

Human natural (KTAb), murine monoclonal (KTMAb), and single-chain recombinant (KTScFv) candidacidal antibodies representing the internal image of a killer toxin from the yeast Pichia anomala (KT), characterized by a wide spectrum of antibiotic activity, exerted a lethal effect against a KT-sensitive multidrug-resistant isolate of Mycobacterium tuberculosis. KTMAb and KTScFv were produced by the hybridoma and DNA technologies, respectively, from the spleen lymphocytes of animals immunized with the idiotype of a KT-neutralizing MAb (MAb KT4), while KTAb were purified against MAb KT4 from the vaginal fluid of women infected with Candida albicans cells bearing an idiotype-like KT cell wall receptor. Mycobactericidal activity was related to the binding of KTAb, KTMAb, and KTScFv to the cell surface of KT-sensitive bacterial cells and was prevented by specific absorption of KT-like antibodies onto MAb KT4. These data identify a novel potentially useful immunotherapeutic approach to tuberculosis.
Measurement of Delay Mismatch Due to Process Variations by Means of Modified Ring Oscillators (2005)

A novel and effective test circuit to measure cell-to-cell delay mismatch due to process variations is presented. A fully digital control circuit that efficiently realizes the technique is also described. The proposed test structure is realized by a series of modified ring oscillators that minimize factors of inaccuracy. The results of a simulation using 0.18 /spl mu/m CMOS technology show the feasibility of the technique. This test structure can be beneficial in thoroughly characterizing the effects of systematical process variations inside the chip.
Kinetics and reaction chemistry for slow pyrolysis of enzymatic hydrolysislignin and organosolv extracted lignin derived from maplewood (2011)

The kinetics and reaction chemistry for the pyrolysis of Maplewood lignin were investigated using both a pyroprobe reactor and a thermogravimetric analyser mass spectrometry (TGA-MS). Lignin residue after enzymatic hydrolysis and organosolv lignin derived from Maplewood were used to measure the kinetic behaviours of lignin pyrolysis and to analyse pyrolysis product distributions. The enzymatic lignin residue pyrolyzed at lower temperature than that of organosolv lignin. The differential thermogravimetric (DTG) peaks for pyrolysis of the enzymatic residue were more similar to the DTG peaks for pyrolysis of the original Maplewood than DTG of the organosolv lignin. The condensable liquid volatile products were collected from a Pyroprobe reactor with a liquid nitrogen trap. The primary monomeric phenolic compounds were guaiacol, syringol, and vanillic acid. However, only 14–36 carbon% of the sample could be detected by GC-MS. Over 60 carbon% of the condensable products were heavy tar molecules that are not detectable by GC-MS. These heavy tar molecules are the primary products from pyrolysis of lignin. Intermediate solid samples were also collected at various pyrolysis temperatures and characterized by elemental analysis, FT-IR, DP-MAS 13C NMR, and TOC. The methoxy groups and ether linkages decreased and the non-protonated aromatic carbon–carbon bonds increased in the solid residues as the pyrolysis temperature increased. The carbon content of the initial lignin feed (derived from enzymatic hydrolysis) and the solid polyaromatics residue (obtained at 773 K) was 58 wt% and 74 wt% respectively. This polyaromatic residue contained about 69 wt% of the original lignin feed. The solid polyaromatics undergo further slow decomposition accompanied by a constant release of carbon dioxide as the pyrolysis reaction continues. The pyrolysis of the enzymatic lignin residue was modelled by two reactions in series. In the first pyrolysis step the lignin was decomposed with an apparent activation energy of 74 kJ mol−1 and a heat of reaction of −8,780 kJ kg−1. The second pyrolysis step had an apparent activation energy of 110 kJ mol−1 and a heat of reaction of −2,819 kJ kg−1. Lignin pyrolysis has lower activation energies and higher heats of reaction than cellulose pyrolysis.
On the use of linear programming for dynamic subchannel and bit allocation in multiuser OFDM (2002)

Adaptive subcarrier allocation and adaptive modulation for multiuser orthogonal frequency division multiplexing (OFDM) is considered. The optimal subcarrier and bit allocation problems, that have been formulated in Wong et al., (1999), and Rhee et al., (2000), as nonlinear optimizations, are converted into linear ones and solved by integer programming (IP). A suboptimal approach that separately performs subcarrier allocation and bit loading is proposed. It is shown that subcarrier allocation in this approach can be optimized by the linear programming (LP) relaxation of the IP. Comparison through computer simulation indicates that performance of the suboptimal approach can be close to that of the optimal.
Copper(II) Complexes with Subnormal Magnetic Moments (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCopper(II) Complexes with Subnormal Magnetic MomentsMichinobu Kato, Hans B. Jonassen, and James C. FanningCite this: Chem. Rev. 1964, 64, 2, 99–128Publication Date (Print):April 1, 1964Publication History Published online1 May 2002Published inissue 1 April 1964https://pubs.acs.org/doi/10.1021/cr60228a003https://doi.org/10.1021/cr60228a003research-articleACS PublicationsRequest reuse permissionsArticle Views2506Altmetric-Citations590LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Molecular Characteristics of DNA-Alkylating PI Polyamides Targeting RUNX Transcription Factors (2019)

The runt-related transcription factor (RUNX) family has been associated with cancer development. The binding of RUNX family members to specific DNA sequences is hypothesized to promote the expression of downstream genes and cause cancer proliferation. On the basis of this proposed mechanism of cancer growth, we developed conjugate 1, which inhibits the binding of RUNX to its target DNA. Conjugate 1 is a DNA-alkylating pyrrole-imidazole (PI) polyamide conjugate containing chlorambucil as an anticancer agent. Conjugate 1 was reported to have a marked anticancer effect in mouse models of acute myeloid leukemia. Although the effectiveness of 1 has been demonstrated in vivo, the detailed mechanism by which it alkylates DNA is unknown. Here, we chemically elucidated the molecular characteristics of conjugate 1 to confirm its potential as a RUNX-inhibiting drug. We also generated an alternative conjugate 2, which targets the same DNA sequence, by replacing one pyrrole with β-alanine. Comparison of the characteristics of conjugates 1 and 2 suggested that reaction selectivity and binding affinity to the RUNX-binding sequence were improved by the introduction of β-alanine. These findings indicate the possibility of DNA-alkylating PI polyamides as candidates for cancer chemotherapeutics.
An active source routing protocol for ad hoc networks (2005)

The existing reactive protocols passively invoke route maintenance only when the path being used is broken, and could not acquire shorter paths as long as the current route is available. This paper proposes an active source routing (ASR) protocol using periodic route update combined with gratuitous route acknowledgement messages for dynamically discovering shorter paths and obtaining the up-to-date network topology information. Every route associated with an expiry time will be removed if it has not been used or updated within a period time. Simulation results show that ASR is slightly affected by the mobility under moderate load and provides significantly higher throughput and lower delay than DSR, especially it can benefit from the increased number of nodes. Its overall performance degrades only under heavy load.
<i>De Novo</i> Determination of the Crystal Structure of a Large Drug Molecule by Crystal Structure Prediction-Based Powder NMR Crystallography (2013)

The crystal structure of form 4 of the drug 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid is determined using a protocol for NMR powder crystallography at natural isotopic abundance combining solid-state (1)H NMR spectroscopy, crystal structure prediction, and density functional theory chemical shift calculations. This is the first example of NMR crystal structure determination for a molecular compound of previously unknown structure, and at 422 g/mol this is the largest compound to which this method has been applied so far.
Elucidation of tonic and activated B-cell receptor signaling in Burkitt’s lymphoma provides insights into regulation of cell survival (2016)

Burkitt's lymphoma (BL) is a highly proliferative B-cell neoplasm and is treated with intensive chemotherapy that, because of its toxicity, is often not suitable for the elderly or for patients with endemic BL in developing countries. BL cell survival relies on signals transduced by B-cell antigen receptors (BCRs). However, tonic as well as activated BCR signaling networks and their relevance for targeted therapies in BL remain elusive. We have systematically characterized and compared tonic and activated BCR signaling in BL by quantitative phosphoproteomics to identify novel BCR effectors and potential drug targets. We identified and quantified ∼16,000 phospho-sites in BL cells. Among these sites, 909 were related to tonic BCR signaling, whereas 984 phospho-sites were regulated upon BCR engagement. The majority of the identified BCR signaling effectors have not been described in the context of B cells or lymphomas yet. Most of these newly identified BCR effectors are predicted to be involved in the regulation of kinases, transcription, and cytoskeleton dynamics. Although tonic and activated BCR signaling shared a considerable number of effector proteins, we identified distinct phosphorylation events in tonic BCR signaling. We investigated the functional relevance of some newly identified BCR effectors and show that ACTN4 and ARFGEF2, which have been described as regulators of membrane-trafficking and cytoskeleton-related processes, respectively, are crucial for BL cell survival. Thus, this study provides a comprehensive dataset for tonic and activated BCR signaling and identifies effector proteins that may be relevant for BL cell survival and thus may help to develop new BL treatments.
Hierarchical Nanoporous Glass with Antireflectivity and Superhydrophilicity by One-Pot Etching (2014)

We have developed a hierarchical nanoporous layer (HNL) on silicate glass by a simple one-pot etching method. The HNL has a three-dimensionally continuous spongelike structure with a pore size of a few tens of nanometers on its apparent surface. The pore size gradually decreases from the apparent surface to the HNL-bulk interface. This HNL bestows significant properties to glass: low optical reflectivity that reflects 7% less visible light than nontreated glass and long-persistence superhydrophilicity that keeps its water contact angle at about 5° for more than 1 year. The superhydrophilicity also realizes antifogging and antifouling functionalities.
A Facile One-Pot Synthesis of Chiral β-Amino Esters (2005)

We report a facile one-pot synthesis of chiral β-amino ­esters via direct reductive amination of β-keto esters with ­ammonium acetate (NH4OAc) and H2 in the presence of chiral Ru-ClMeOBIPHEP catalysts using 2,2,2-trifluoroethanol (TFE) as a solvent, leading to β-amino esters in high yields with high ­enantioselectivities (up to 99% ee).
ÜBER DIE HYDROLYSE DER ADENOSINTRIPHOSPHORSÄURE DURCH PHOSPHOMONOESTERASE UND PYROPHOSPHATASE (1935)

ÜBER DIE HYDROLYSE DER ADENOSINTRIPHOSPHORSÄURE DURCH PHOSPHOMONOESTERASE UND PYROPHOSPHATASE Get access TOSHIYUKI SATOH TOSHIYUKI SATOH Aus dem medizinisch-chemischen Institut der Medizinischen Akademie zu Chiba Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Biochemistry, Volume 21, Issue 1, January 1935, Pages 19–36, https://doi.org/10.1093/oxfordjournals.jbchem.a125437 Published: 01 January 1935 Article history Received: 15 August 1934 Published: 01 January 1935
Atomic layer deposition of zinc sulfide with Zn(TMHD)2 (2012)

The atomic layer deposition (ALD) of ZnS films with Zn(TMHD)2 and in situ generated H2S as precursors was investigated, over a temperature range of 150–375 °C. ALD behavior was confirmed by investigation of growth behavior and saturation curves. The properties of the films were studied with atomic force microscopy, scanning electron microscopy, energy-dispersive x-ray spectroscopy, ultraviolet–visible–infrared spectroscopy, and extended x-ray absorption fine structure. The results demonstrate a film that can penetrate a porous matrix, with a local Zn structure of bulk ZnS, and a band gap between 3.5 and 3.6 eV. The ZnS film was used as a buffer layer in nanostructured PbS quantum dot solar cell devices.
Very Long Term Field of View Prediction for 360-degree Video Streaming (2019)

360-degree videos have gained increasing popularity in recent years with the developments and advances in Virtual Reality (VR) and Augmented Reality (AR) technologies. In such applications, a user only watches a video scene within a field of view (FoV) centered in a certain direction. Predicting the future FoV in a long time horizon (more than seconds ahead) can help save bandwidth resources in on-demand video streaming while minimizing video freezing in networks with significant bandwidth variations. In this work, we treat the FoV prediction as a sequence learning problem, and propose to predict the target user's future FoV not only based on the user's own past FoV center trajectory but also other users' future FoV locations. We propose multiple prediction models based on two different FoV representations: one using FoV center trajectories and another using equirectangular heatmaps that represent the FoV center distributions. Extensive evaluations with two public datasets demonstrate that the proposed models can significantly outperform benchmark models, and other users' FoVs are very helpful for improving long-term predictions.
Introduction (2005)

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Electrocatalytic activity of cytochrome c for the reduction of nitric oxide (1994)

Abstract Sodium nitrite in acidic solutions produces a voltammetric cathodic wave starting from −0.5 V (vs. Ag/AgCl) in the presence of a small amount of cytochrome c (cyt c), in which cyt c works as a catalyst for the electroreduction of nitric oxide produced by the disproportionation reaction of nitrite. Hemoglobin (Hb) and myoglobin (Mb) are also effective as catalysts for this type of reaction.
Reaction of N-arylcarbamoyl-1,4-benzoquinone imines with sodium arenesulfinates (2014)

N-Arylcarbamoyl-1,4-benzoquinone imines possessing at least one free ortho position with respect to the carbonyl carbon atom in the quinoid ring react with sodium arenesulfinates according to the nucleophilic 1,4-addition pattern with complete regioselectivity. If both ortho positions are occupied, the reaction gives a mixture of products where the major ones are 1,6- and 6,1-adducts formed according to the radical ion mechanism.
The interactive balloon: Sensing, actuation and behavior in a common object (1996)

In the not too distant future, new materials for sensing and actuation, together with high-density, low-power electronics and embedded computation, will bring interaction and intelligence to commonplace inanimate objects in our environment. as a simple but illustrative example, we have built balloons that can interact conversationally. this paper describes this system: the piezoelectric foil that works as an acoustic pickup and speaker on the balloon, its audio characteristics, the driving electronics, the signal processing, and some applications of this technology at the MIT media laboratory.
Photoelectric and Thermionic Properties of Nickel (1949)

The photoelectric and thermionic properties of spectroscopically pure nickel were studied through a wide range of temperatures including the Curie temperature, 350\ifmmode^\circ\else\textdegree\fi{}C. The samples were studied after having been subjected to long outgassing processes. A marked change occurs in the slope of the temperature-photoelectric current curves at the Curie temperature. This change is accounted for by an increase in the work function and a change in the probability factor $\ensuremath{\alpha}$. The work function of carefully outgassed nickel was found to be 5.05\ifmmode\pm\else\textpm\fi{}0.05 electron volts below 623\ifmmode^\circ\else\textdegree\fi{}K. At this temperature the work function increases becoming 5.20\ifmmode\pm\else\textpm\fi{}0.05 electron volts at 1108\ifmmode^\circ\else\textdegree\fi{}K. A work function of 5.24 electron volts was determined thermionically at temperatures of 1150\ifmmode^\circ\else\textdegree\fi{}K and above.
Evaluation of the effects of sagging shifts on isocenter accuracy and image quality of cone‐beam CT from kV on‐board imagers<sup>*</sup> (2009)

To investigate the effects of sagging shifts of three on-board kV imaging systems (OBI) on the isocenter positioning accuracy and image quality of cone-beam CT (CBCT). A cubical phantom having a metal marker in the center that can be aligned with the radiation isocenter was used to measure sagging shifts and their variation with gantry angle on three Varian linacs with kV on-board imaging systems. A marker-tracking algorithm was applied to detect the shadow of the metal marker and localize its center in the two-dimensional cone-beam radiographic projections. This tracking algorithm is based on finding the position of maximum cross-correlation between a region-of-interest from a template image (including the metal marker) and the projections containing the shadow of the metal marker. Sagging shifts were corrected by mapping the center of the metal marker to a reference position for all projections acquired over a full gantry rotation (0-360 degrees). The sag-corrected radiographic projections were then used to reconstruct CBCT using Feldkamp back-projection. A standard quality assurance phantom was used to evaluate the image quality of CBCT before and after sagging correction. Sagging affects both the positioning accuracy of the OBI isocenter and the CBCT image quality. For example, on one linac, the position of the marker on the cone-beam radiographic projections depends on the angular view and has maximal shifts of about 2 mm along the imager x-direction (patient's cross-plane). Sagging produces systematic shifts of the OBI isocenter as large as 1 mm posterior and 1 mm left in patient coordinates relative to the radiation isocenter. Further, it causes spatial distortion and blurring in CBCT image reconstructed from radiographic projections that are not corrected for OBI sagging. CBCT numbers vary by about 1% in full-fan scans and up to 3.5% in half-fan scans because of sagging. In order to achieve better localization accuracy in image-guided radiation therapy, sagging shifts of the kV OBI need to be corrected. In addition, correction of sagging improves image and provides better visualization of internal structures. Frequent quality assurance is required to monitor and maintain standards of variations in the mechanical accuracy of isocenter and image quality of CBCT because of sagging shifts.
Genome Targeted Introgression of Resistance to African Stem Rust from <i>Aegilops sharonensis</i> into Bread Wheat (2017)

Many accessions of the wheat wild relative Sharon goatgrass ( Eig., ) are resistant to African races of the stem rust pathogen (i.e., Ug99 group races), which currently threaten wheat production worldwide. A procedure was designed to introgress the respective resistances to specific bread wheat genomes by producing plants homozygous for the A and B genomes and hemizygous for the D and S genomes or homozygous for the A and D genomes and hemizygous for the B and S genomes. In these genotypes, which lack the allele, homeologous pairing was expected mainly between chromosomes of the D and S genomes or B and S genomes, respectively. An antigametocidal (AG) wheat mutant () was used to overcome gametocidal effects. Wheat lines initially found resistant at the seedling stage were also highly resistant at the adult plant stage in rust nurseries established in the field. DNA of 41 selected homozygous resistant lines, analyzed by the Axiom wheat 820K SNP array, showed alien chromatin mainly in wheat chromosomes 1B, 1D, and 5B. This work suggests that, in most cases, it is possible to target introgressions into the homeologous chromosome of a selected genome of bread wheat.
Sophisticated ROP Prediction Technologies Based on Neural Network Delivers Accurate Drill Time Results (2010)

Abstract Accurately predicting the rate of penetration (ROP) is a prominent factor affecting economic and engineering decisions during well planning. However, ROP prediction based on simple algorithms applied to offset wells has historically yielded mixed results. To improve ROP predicting capabilities, the provider is applying an artificial neural network (ANN) to analyze offset drilling data. The system has significantly improved the ability to accurately predict drilling performance, despite expected changes in lithology, hole size, bit type and mud properties. The flexibility of the software package allows engineers to analyze a wide range of information and deliver high-quality ROP predictions based on previous experience and data from offset wells. The process includes detail scrutiny of the offset and training of the ANN system until the neural network is validated. The simulation is then run to solve expected ROP, using any changed drilling conditions as input. In a recent case, an operator required a well that would have to be drilled deeper than offsets and with different borehole sizes. By applying the neural network capabilities, engineers were able to deliver analytical ROP predictions for the planned well, including quality result for different lithologies with a wide range of rock strength values. This paper will focus on the new ANN technologies being utilized for predicting drilling performance. It will also include a case study that documents its successful application.