gebhart/patrepeval huggingface dataset:
MOLECULAR WEIGHT DISTRIBUTION OF NONIONIC SURFACTANTS. I. SURFACE AND INTERFACIAL TENSION OF NORMAL DISTRIBUTION AND HOMOGENEOUS p,t-OCTYLPHENOXYETHOXYETHANOLS (OPE'S) (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMOLECULAR WEIGHT DISTRIBUTION OF NONIONIC SURFACTANTS. I. SURFACE AND INTERFACIAL TENSION OF NORMAL DISTRIBUTION AND HOMOGENEOUS p,t-OCTYLPHENOXYETHOXYETHANOLS (OPE'S)E. H. Crook, D. B. Fordyce, and G. F. TrebbiCite this: J. Phys. Chem. 1963, 67, 10, 1987–1994Publication Date (Print):October 1, 1963Publication History Published online1 May 2002Published inissue 1 October 1963https://pubs.acs.org/doi/10.1021/j100804a010https://doi.org/10.1021/j100804a010research-articleACS PublicationsRequest reuse permissionsArticle Views747Altmetric-Citations195LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Effect of dehulling and heat processing on nutritional value of sesame proteins (1974)

Abstract Processing of edible sesame flour involves use of hot lye treatment of the seed for dehulling followed by drying, screw pressing, and solvent extraction. The effect of such processing on protein quality, especially lysine availability has been studied. The enzymatic digestibility of protein is improved as a result of dehulling, and lysine present in the flour exhibits remarkable stability to heat treatment, the maximum losses being less than 15% even under drastic conditions of heat treatment of the flour (1 kg/cm 2 for 60 min). Supplementation of the flour with lysine at an optimal level of 1.25 g L‐lysine HCl/100 g flour enhances the nutritive value of protein, making it comparable to that of milk powder.
ChemInform Abstract: Heavy Metal Extraction and Absorption by Calixarenes. (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Artistic Intervention Residencies And Their Intermediaries: A Comparative Analysis (2012)

Part of the Arts and Humanities Commons, and the Business Commons To access supplemental content and other articles, click here. This Practice Article is brought to you for free and open access by DigitalCommons@WPI. It has been accepted for inclusion in Organizational Aesthetics by an authorized administrator of DigitalCommons@WPI.
Physical and Conformational Properties of Synthetic Idealized Signal Sequences Parallel Their Biological Function (1995)

Transported proteins often contain an extension sequence called the signal peptide. The alkaline phosphatase (PhoA) signal sequence represents a typical signal peptide for comparison to idealized sequences both in vivo and in vitro. We have designed a series of idealized signal sequences which vary in amino terminal charge and core region hydrophobicity with minimal variation in amino acid composition. The idealized core regions contain different proportions of leucine and alanine residues, effectively producing hydrophobicities above and below the threshold level required for efficient secretion. The flanking amino and carboxyl termini were designed to maintain the general features and relative hydrophobicity of their counterparts in the wild-type PhoA signal sequence. Using the phoA gene, the signal peptide region was modified to generate mutants corresponding to the model sequences. Transport studies in Escherichia coli confirmed that completely idealized signal sequences, which lack a helix-breaking proline or glycine residue, can be functional if the core region is sufficiently hydrophobic and that one positively charged residue in the amino terminus is adequate for efficient transport. The corresponding peptides were chemically synthesized and exhibited HPLC retention times that reflect the relative hydrophobicities of the sequences. Structural analyses of the isolated peptides by circular dichroism demonstrate solvent dependence and exceptionally stable alpha-helix formation by the functional signal peptides in trifluoroethanol. Although leucine and alanine residues are often predicted to have similar propensities for forming an alpha-helix, considerably higher alpha-helical content is observed in the signal peptides which contain predominantly polyleucine core regions.(ABSTRACT TRUNCATED AT 250 WORDS)
Extending Intrusion Detection with Alert Correlation and Intrusion Tolerance (2003)

Intrusion detection is an important security tool.It has the possibility to provide valuable information about the current status of security.However, as enterprises deploy multiple intrusion detection sensors at key points in their networks, the issue of correlating messages from these sensors becomes increasingly important.A correlation capability reduces alert volume, and potentially improves detection performance through sensor reinforcement or complementarity.Correlation is especially advantageous when heterogeneous sensors are employed because of the potential to aggregate different views of the same incident.This thesis studies a number of different properties of intrusion alert correlation, such as standard formats and similarity metrics.A conceptual framework is suggested, followed by three different case studies.Firstly, a router based IDS is implemented and analyzed.The quality of the event source is found to be unreliable and the consequences for intrusion detection and correlation are evaluated.Secondly, a case study of live traffic analysis is performed using heterogeneous intrusion alert correlation.A successful correlation is presented.Thirdly, the possibility to implement intrusion alert correlation using open source tools is evaluated.A simple prototype is implemented.However, even if the performance of the intrusion detection systems increases, there will always be intrusions.One way to remedy this problem is to use fault tolerant techniques in a new setting, providing intrusion tolerance.This results in a system that will continue to provide a valid service, possibly with a performance penalty, in spite of current intrusion attempts.This thesis studies different ways to implement intrusion tolerant services.Additionally, an intrusion tolerant reverse proxy server is implemented and analyzed.All in all, we show the value of intrusion alert correlation and intrusion tolerance in different settings.
Special and Practical Issues in Cross Country Skiing (2003)

This chapter contains section titled: Overreaching and Recovery from Training Adjustments to Travelling Across Time Zones Haemoglobin Tests, Erythropoietin and Doping Control Altitude Training and Simulated Altitude Training Nutritional Advice for Cross Country Skiers Carbohydrate Loading and Fluid Replacement Recommended Reading
Serum Enzyme Activities in Full-Term Asphyxiated and Healthy Newborns: Enzyme Kinetics during the First 144 Hours of Life (1993)

Little is known about the kinetics of most serum enzymes during the first hours of life, and even less about the effect on such enzyme activities of perinatal hypoxia-ischaemia. It was the aim of the present study to evaluate the serum kinetics of seven differently located cell enzymes in healthy and asphyxiated newborns during the 1st week of life. The serum activities of cytoplasmic and mitochondrial [aspartate aminotransferase (ASAT), creatine kinase (CK), glutamate dehydrogenase (GLDH), lactate dehydrogenase (LDH), and hydroxybutyrate dehydrogenase (HBDH)] and membrane-bound (gamma-glutamyl-transferase and leucine arylaminidase) enzymes were prospectively measured in full-term asphyxiated (n = 49) and healthy (n = 87) newborns during the first 144 h of life. The blood samples were taken serially at five fixed times: 0 (cord), 12, 24, 72, and 144 h postpartum. The asphyxiated newborns had significantly increased serum activities of ASAT, LDH, and HBDH up to 72 h postpartum, whereas healthy newborns showed higher CK and GLDH activities. Only the activities of ASAT, LDH, and HBDH seemed to depend on the oxygen supply of the fetus or newborn. If other causes of increased serum enzyme activities, e.g. liver diseases, haemolytic disorders, tumours, or inborn errors of metabolism, are excluded, elevated serum activities of ASAT, LDH, and HBDH should draw one's attention to a perinatal hypoxic-ischaemic insult of the newborn.
Employee onboarding: identification of best practices in ACRL libraries (2013)

Purpose The purpose of this paper is to identify best practices of employee onboarding, the process by which a new employee is introduced to an organization and its vision, mission, and values. Design/methodology/approach Researchers requested that members of the Personnel Administrators and Staff Development Officers Discussion Group of the Association of College and Research Libraries (ACRL) share documents related to employee onboarding and three researchers independently reviewed the documents. The collected documents were compared to the socialization model proposed by Raymond Noe, including the detailed aspects of the organizational phase and the key components identified in the best practices literature. Findings In total, 17 institutions submitted documentation for review. All institutions discussed at least one or more of the key areas identified in the socialization process. Every institution in the study included a discussion of job expectations and evaluation criteria (100 percent); ten (59 percent) discuss mission, vision, and values; however, topics such as culture (five or 29 percent) and politics (one or 6 percent) were infrequently covered. Onboarding programs varied in length (one week to more than six months). Check lists were the most common tool used to manage the onboarding process. Other notable topics covered include dealing with change, understanding the team‐based environment, diversity, library awards and library fundraising. Research limitations/implications Because of the limited number of documents examined in this study, the research results may lack generalisability. Therefore, researchers are encouraged to test the proposed propositions further. Practical implications Moving from a traditional new employee orientation model to a best‐practices onboarding model will require HR professionals to conduct an internal assessment of the current program. Originality/value Due to the high cost associated with recruiting new employees, the need for new employees to be fully functional and engaged as soon as possible, and the need to communicate performance indicators, the need to share best practices is important.
Design and synthesis of some substrate analog inhibitors of phospholipase A2 and investigations by NMR and molecular modeling into the binding interactions in the enzyme-inhibitor complex (1992)

A series of substrate analogue inhibitors of pancreatic phospholipase A2 has been designed and synthesized. The compounds were tested in a novel dual-screening system based on parallel assays with monomeric and micellar substrates. Intermolecular nuclear Overhauser effects between vinylic protons on one inhibitor and identified active site residues on the bovine pancreatic enzyme have been observed in solution NMR studies of the enzyme-inhibitor complex. It can be deduced from both the biochemical results and the NMR data that the mode of interaction between this type of inhibitor and the active site of phospholipase A2 is essentially the same, irrespective of the presence or absence of an aggregated phospholipid surface. A model of the binding between the enzyme and inhibitor which incorporates the two-dimensional NMR data has been developed. The model can account for the activity of modified inhibitor structures and can be extrapolated to an assessment of the mode of binding of the natural substrate itself.
Surface analysis of WC–Co composite materials (2) Quantitative Auger electron spectrometry (1978)

The unique sensitivity of Auger electron spectrometry (AES) to combined carbon has been exploited in measuring the surface compositions of hot-pressed, conventionally sintered and mixed powders of WC–Co composite materials. AES sensitivity factors for tungsten and carbon (in WC) relative to cobalt were determined. The concentrations of the major elements in hot-pressed samples measured with AES using the relative sensitivity method were compared to those obtained independently by electron microprobe (EMP) and x-ray fluorescence (XRF) techniques. Corollary studies using ion scattering spectrometry (ISS) showed the absence of (1) matrix effects in the AES measurements, (2) preferential sputtering during ion bombardment, and (3) deposition of the easier-to-sputter component (cobalt) onto WC.
권근(權近)이 추구한 유교국가의 국왕상(國王像) 고찰 (2015)

본고는 조선이 유교국가가 되는 과정을 밝히는 것을 목적으로 한다. 유교국가의 키워드를 국왕으로 보고 조선 초기 대표적인 유학자 권근이 정립하려고 하는 국왕상을 조명해 보았다. 권근은 유학관련 저술과 상소를 통해 유교국가의 이상적인 국왕의 면모를 제시하였다. 본고에서는 권근의 저술중『서천견록(書淺見錄)』과『시천견록(詩淺見錄)』, 그리고 상소 중에는 우왕에게...
Effect of an enzyme chewing gum on whole saliva protease levels. (1968)

Abstract : The release of proteolytic enzymes from a 1.5-gm. bolus of chewing gum containing 12 mg. of Rhozyme P-11 was studied. The chewing of this gum brought about tremendous increases in whole saliva protease levels, followed by a nonlinear decrease in concentration as chewing progressed. The curve that best fits this nonlinear decrease is: y = ab to the x power where y is tyrosine (mg./100 ml. saliva), x is time in minutes after introduction of the fresh stick of gum, and b is less than zero. Subjects responded in essentially the same fashion as each new stick of enzyme-containing gum was introduced. The response across four 30-minute periods with fresh gum was so similar that a single curve adequately described the response: log y = 3.1968 - .049827 (x). On the basis of this equation, it could be predicted that chewing a single stick of this enzyme gum would maintain the salivary protease concentration at a level higher than the control level for approximately 50 minutes. (Author)
Bottleneck Identification Techniques Leading to Simplified Performance Models for Efficient Design Space Exploration in VLSI Memory Systems (2010)

High performance VLSI systems are being built as multi-processor systems-on-chip. The number of processors and their performance is rising rapidly while the change is slower for the memories. The memory system is often a performance bottleneck in terms of either its bandwidth or latency. We propose sensitivity analysis as a means to pin-point the bottleneck. We introduce a novel randomized technique to measure the sensitivities within cycle accurate simulators. The sensitivity measures identify the bottleneck regions of the design space, within which simplified performance models can be used for optimization. We demonstrate this methodology on the Augmint-MemSim simulator, which is a cycle accurate model for multi-processor systems with a distributed memory sub-system. We empirically show that: (i) Performance predictions from simplified models are strongly correlated with the simulator in the high sensitivity regions. (ii) The simplified models speed up design space exploration by 2 - 3 orders of magnitude over the simulator resulting in better design solutions.
The Concise Guide to PHARMACOLOGY 2015/16: Overview (2015)

The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13347/full. This compilation of the major pharmacological targets is divided into eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.
Asterixis and encephalopathy following metrizamide myelography: Investigations into possible mechanisms and review of the literature (1981)

Marked asterixis occurred in two patients following metrizamide myelography. One also suffered generalized seizures and the other had severe stuttering speech for seven days. The spectrum of toxic manifestations of metrizamide is reviewed with emphasis on the unusual lethargy and other depressive effects seen with this relatively safe agent. The hypothesis that metrizamide exerts a ouabain-like effect on the cortical surface was tested. Metrizamide in concentrations as high as 20 mM had no inhibitory effect on rat cerebral K+-para-nitrophenylphosphatase, a partial reaction of (Na+K+)-adenosine triphosphatase. Because metrizamide is a 2-deoxyglucose analogue, a competitive inhibition of hexokinase at the first step in glycolysis was also postulated. Metrizamide was found to competitively inhibit commercial (microbial) hexokinase. The Michaelis constant for glucose rises from 0.13 to 0.25 to 0.33 to 0.91 mM in the presence of 0, 0.4, 1.0, and 2.0 mM metrizamide, respectively. Since the concentration of metrizamide over the cerebral cortex after routine myelography may be approximately 50 mM compared with a glucose concentration of only 3.6 mM (65 mg/dl), it is postulated that impaired brain glucose metabolism may be responsible for some of the toxic effects of metrizamide.
p120 Catenin-Associated Fer and Fyn Tyrosine Kinases Regulate β-Catenin Tyr-142 Phosphorylation and β-Catenin-α-Catenin Interaction (2003)

beta-Catenin has a key role in the formation of adherens junction through its interactions with E-cadherin and alpha-catenin. We show here that interaction of beta-catenin with alpha-catenin is regulated by the phosphorylation of beta-catenin Tyr-142. This residue can be phosphorylated in vitro by Fer or Fyn tyrosine kinases. Transfection of these kinases to epithelial cells disrupted the association between both catenins. We have also examined whether these kinases are involved in the regulation of this interaction by K-ras. Stable transfectants of the K-ras oncogene in intestinal epithelial IEC18 cells were generated which show little alpha-catenin-beta-catenin association with respect to control clones; this effect is accompanied by increased Tyr-142 phosphorylation and activation of Fer and Fyn kinases. As reported for Fer, Fyn kinase is constitutively bound to p120 catenin; expression of K-ras induces the phosphorylation of p120 catenin on tyrosine residues increasing its affinity for E-cadherin and, consequently, promotes the association of Fyn with the adherens junction complex. Yes tyrosine kinase also binds to p120 catenin but only upon activation, and stimulates Fer and Fyn tyrosine kinases. These results indicate that p120 catenin acts as a docking protein facilitating the activation of Fer/Fyn tyrosine kinases by Yes and demonstrate the role of these p120 catenin-associated kinases in the regulation of beta-catenin-alpha-catenin interaction.
[Study of variables in the planning of nursing personnel in hospitals of Porto Allegre]. (1997)

The study intends to discuss the reality of nursing personnel planning, trying to describe the qualitative and quantitative variables that are involved in this process in hospitals of Porto Alegre city. In spite of numberless variables found, we can verify a great diversity between the criterious accepted by the nursing chief's and the inexistence of official criterious. The data analisys allowed grouping the variables in four main categories: hospital, nursing service, unit and clientele. To exist best utilization the quantitative variables related unit and clientele categories and restriction of autonomy nursing service to decide about this theme.
Oxydes céramiques élaborés par voie mécanochimique (1993)

Des modifications structurales produites par sollicitation mécanique dans un broyeur planétaire à haute énergie ont été étudiées pour différents oxydes binaires ou ternaires à applications céramiques. Des transformations de phase ont été mises en évidence pour les dioxydes de titane et de zirconium et pour le silicate de zirconium (zircon) qui devient amorphe après un broyage prolongé. Par mécanosynthèse, nous avons préparé des zircones stabilisées à la chaux et à l'oxyde d'yttrium, ainsi que des phases amorphes nouvelles obtenues à partir de mélanges de poudres d'alumine et de zircone.
Facile Synthesis of Pd−Cd Nanostructures with High Capacity for Hydrogen Storage (2009)

We report on the direct growth of novel Pd-Cd nanostructures with controllable composition via a facile hydrothermal reduction method. Our study demonstrates that the addition of Cd significantly changes the morphology and properties of the formed Pd-Cd nanostructures. Our electrochemical measurements show that the Pd-Cd nanostructures with 10-15% of Cd possess the highest capacity for hydrogen sorption, over 15 times greater than the nanoporous Pd networks. The significant enhancement by Cd can be attributed to a combination of the formation of small dendritic structures, dilation of the lattice constant, and decrease of the crystallite size. The easy fabrication and high capacity for hydrogen sorption make the novel Pd-Cd nanomaterials very promising for hydrogen storage.
Scandinavian guidelines for initial management of minimal, mild and moderate head injuries in adults: an evidence and consensus-based update (2013)

We present the updated SNC guidelines for initial management of minimal, mild and moderate head injury in adults including criteria for computed tomography (CT) scan selection, admission and discharge with suggestions for monitoring routines and discharge advice for patients. The guidelines are designed to primarily detect neurosurgical intervention with traumatic CT findings as a secondary goal. For elements lacking good evidence, such as in-hospital monitoring, routines were largely based on consensus. We suggest external validation of the guidelines before widespread clinical use is recommended.