gebhart/patrepeval huggingface dataset:
SOURCES OF RESISTANCE TO Fusarium oxysporum f. sp.cubense IN BANANA GERMPLASM (2018)

ABSTRACT Fusarium wilt (syn= Panama disease), caused by Fusarium oxysporum f. sp. cubense (FOC), is one of the most destructive diseases of banana, being genetic resistance the main management strategy for this disease. Since the pathogen is constantly evolving to supplant the genetic resistance, new sources of resistance must be investigated by genetic improvement programs aiming to developing new varieties. The objective of the present study was to identify sources of resistance from the different accessions maintained in the banana active germplasm bank (BAGB) at Embrapa Mandioca e Fruticultura. Forty-one BAGB accessions were evaluated, including 17 diploids, 21 triploids, and two tetraploids. The area under the disease progress curve, disease index, and incubation period were also evaluated. In relation to FOC resistance, there is genetic variability available among the BAGB accessions. The genotype M53 is notable for the complete resistance it expressed, and the accessions Birmanie, PA Songkla, Pirua, Imperial, Poyo, Ambei, Walebo, and Kongo FRF 1286 expressed quantitative resistance.
Continuous surface charge polarizable continuum models of solvation. I. General formalism (2010)

Continuum solvation models are appealing because of the simplified yet accurate description they provide of the solvent effect on a solute, described either by quantum mechanical or classical methods. The polarizable continuum model (PCM) family of solvation models is among the most widely used, although their application has been hampered by discontinuities and singularities arising from the discretization of the integral equations at the solute-solvent interface. In this contribution we introduce a continuous surface charge (CSC) approach that leads to a smooth and robust formalism for the PCM models. We start from the scheme proposed over ten years ago by York and Karplus and we generalize it in various ways, including the extension to analytic second derivatives with respect to atomic positions. We propose an optimal discrete representation of the integral operators required for the determination of the apparent surface charge. We achieve a clear separation between "model" and "cavity" which, together with simple generalizations of modern integral codes, is all that is required for an extensible and efficient implementation of the PCM models. Following this approach we are now able to introduce solvent effects on energies, structures, and vibrational frequencies (analytical first and second derivatives with respect to atomic coordinates), magnetic properties (derivatives with respect of magnetic field using GIAOs), and in the calculation more complex properties like frequency-dependent Raman activities, vibrational circular dichroism, and Raman optical activity.
Plunder and Stowaways: Incorporation of Cellular Proteins by Enveloped Viruses (2005)

To be successful and have the opportunity to replicate properly, a virus has to thwart or, just the reverse, boost many systems of the host cell. Given that host cells have evolved to eliminate these hostile parasites, a fierce battle ensues. There is now compelling evidence that enveloped virions released from infected cells will carry the vestiges of this battle both internally and externally. The focus of the present minireview will be the incorporation of the host cellular proteins into or onto the newly formed viruses. The roles of a few of these host cellular proteins have been studied, albeit very recently, because of their implication in the biology of some viruses. But for the vast majority, only the observation of their incorporation has been reported in the scientific literature.

The various studies in this research area have been conducted with eukaryotic cells infected primarily with RNA enveloped viruses. Human immunodeficiency virus type 1 (HIV-1) has been the most extensively studied in this respect, but other viruses have also contributed to a better understanding of this intriguing phenomenon. A list of the molecules that have been reported to be embedded in some enveloped viruses is shown in Table ​Table1.1. The processes through which cellular proteins are acquired by viruses are still ill defined. Here we will describe and discuss the roles, or potential roles, that the major cellular proteins found associated with enveloped viruses may play in their life cycles. First, the internally associated host cell molecules will be described, and in a second section, the cell surface constituents found included within the envelopes of different viruses will be introduced.



TABLE 1.

Host cellular molecules acquired by some enveloped viruses
Role of Extracellular Superoxide Dismutase in the Mouse Angiotensin Slow Pressor Response (2006)

Low rates of angiotensin II (Ang II) infusion raise blood pressure, renal vascular resistance (RVR), NADPH oxidase activity, and superoxide. We tested the hypothesis that these effects are ameliorated by extracellular superoxide dismutase (EC-SOD). EC-SOD knockout (-/-) and wild type (+/+) mice were equipped with blood pressure telemeters and infused subcutaneously with Ang II (400 ng/kg per minute) or vehicle for 2 weeks. During vehicle infusion, EC-SOD -/- mice had significantly (P<0.05) higher MAP (+/+: 107+/-3 mm Hg versus -/-: 114+/-2 mm Hg; n=11 to 14), RVR, lipid peroxidation, renal cortical p22(phox) expression, and NADPH oxidase activity. Ang II infusion in EC-SOD +/+ mice significantly (P<0.05) increased MAP, RVR, p22(phox), NADPH oxidase activity, and lipid peroxidation. Ang II reduced SOD activity in plasma, aorta, and kidney accompanied by reduced renal EC-SOD expression. During Ang II infusion, both groups had similar values for MAP (+/+ Ang II: 125+/-3 versus -/- Ang II: 124+/-3 mmHg; P value not significant), RVR, NADPH oxidase activity, and lipid peroxidation. SOD activity in the kidneys of Ang II-infused mice was paradoxically higher in EC-SOD -/- mice (+/+: 8.8+/-1.2 U/mg protein(-1) versus -/-: 13.7+/-1.6 U/mg protein(-1); P<0.05) accompanied by a significant upregulation of mRNA and protein for Cu/Zn-SOD. In conclusion, EC-SOD protects normal mice against oxidative stress by attenuating renal p22(phox) expression, NADPH oxidase activation, and the accompanying renal vasoconstriction and hypertension. However, during an Ang II slow pressor response, renal EC-SOD expression is reduced and, in its absence, renal Cu/Zn-SOD is upregulated and may prevent excessive Ang II-induced renal oxidative stress, renal vasoconstriction, and hypertension.
Stress control during thermal annealing of copper interconnects (2011)

Grain growth of Cu interconnects in an ultralow k dielectric was achieved at an elevated anneal temperature of 300 °C without stress voiding related problems. For this, a TaN metal passivation layer was deposited on the Cu interconnect surface prior to the thermal annealing process, which suppressed void formation within the Cu features during the anneal process and reduced inelastic deformation within the interconnects after cooling down to room temperature. As compared to the conventional anneal process at 100 °C, the passivation layer enabled further Cu grain growth at elevated temperatures, which then resulted in lower electrical resistance in the Cu interconnects.
Direct Detection of DNA with an Electrocatalytic Threading Intercalator (2004)

Herein we report the synthesis, intercalating properties, and analytical applications of an imidazole-substituted naphthalene diimide, N,N'-bis(3-propylimidazole)-1,4,5,8-naphthalene diimide (PIND), functionalized with electrocatalytic redox moieties. PIND was prepared in a single-step reaction from the corresponding dianhydride. Attachment of the redox moieties to PIND relied upon ligand exchange with one of the liable chloride ligands of an Os(bpy)2Cl2 (bpy = 2,2'-bipyridine) complex. The Os(bpy)2Cl2 complex was grafted onto PIND through coordinative bonds with the two imidazole groups at its termini, forming a PIND-[Os(bpy)2Cl]+ compound (PIND-Os). Gel electrophoretic studies revealed that PIND-Os binds more strongly to double-stranded DNA (ds-DNA) than its parent compound 1,4,5,8-naphthalene diimide. The naphthalene diimide group binds to ds-DNA in a "classical" threading intercalation mode, while the two Os(bpy)2Cl+ pendants interact with DNA via electrostatic interaction, reinforcing the intercalation by "locking up" the naphthalene diimide group in place. An electrochemical biosensor was fabricated using the redox-active and catalytic PIND-Os intercalator. An increase in sensitivity of 2500-fold over direct voltammetry was obtained in electrocatalytic amperometry, making this an interesting system for amperometric DNA sensing. Under optimized experimental conditions, the biosensor allowed the detection of a 50-mer target DNA in the range of 1.0-300 pM with a detection limit of 600 fM (1.5 amol, 23 fg).
THE PALLIAL RIDGE OF NEOTRIGONIA FUNCTIONAL SIPHONS WITHOUT MANTLE FUSION (1974)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
The <i>Saccharomyces cerevisiae OXA1</i> gene is required for the correct assembly of cytochrome <i>c</i> oxidase and oligomycin‐sensitive ATP synthase (1996)

The nuclear gene OXA1 was first isolated in Saccharomyces cerevisiae and found to be required at a post-translational step in cytochrome c oxidase biogenesis, probably at the level of assembly. Mutations in OXA1 lead to a complete respiratory deficiency. The protein Oxa1p is conserved through evolution and a human homolog has been isolated by functional complementation of a yeast oxa1- mutant. In order to further our understanding of the role of Oxa1p, we have constructed two yeast strains in which the OXA1 open reading frame was almost totally deleted. Cytochrome spectra and enzymatic activity measurements show the absence of heme aa3 and of a cytochrome c oxido-reductase activity and dramatic decrease of the oligomycin sensitive ATPase activity. Analysis of the respiratory complexes in non-denaturing gels reveals that Oxa1p is necessary for the correct assembly of the cytochrome c oxidase and the ATP synthase complex.
SCTP over satellite networks (2004)

The stream control transmission protocol (SCTP) has recently been standardized as a new transport layer protocol in the IP suite. In addition to the core features of TCP, SCTP incorporates a number of advanced and unique features which are not available in TCP. The paper investigates the suitability of SCTP for data communications over satellite links. We describe SCTP features that allow SCTP to utilize the bandwidth of satellite networks better, while at the same time avoiding congestion collapse in a shared network. Finally, we provide recommendations on the use of SCTP over satellite networks.
Polymer Durability (1996)

Chain transfer to monomer during the free-radical polymerization of vinyl chloride is shown to occur, in part, by a mechanism that begins with the abstraction of methylene hydrogen from the polymer by a propagating macroradical The resultant radical then donates a chlorine atom to the monomer to form an allylic structure that can contribute to the thermal instability of poly(vinyl chloride). Double-bond contents found by NMR spectroscopy and their correlation with molecular weights confirm the operation of this transfer process and verify a new theory for transfer to monomer. The theory involves two transfer constants and, allows their values to be obtained.
Transient Power and Quality Events Analysed Using Hilbert Transforms (2012)

This work presents an advanced mathematical tool applicable to the recognition and classification of power system transients and disturbances. Disturbances without a periodic pattern or with a non-linear pattern require a more suitable tool than the Fourier series (Fast Fourier or Windowed Fourier Transforms). To overcome these drawbacks, other tools have been broadly used, such as the wavelet transform. However, the wavelet transform also has some drawbacks such as the lack of adaptivity or interpretation of nonlinear phenomena that the Hilbert and Hilbert Huang Transform techniques could mitigate. The Hilbert techniques transform a time domain function into a space representation both in time and frequency. In the paper, the technique is applied to analyse several short-term and steady events, like a short circuit, a capacitor-switching transient, or a line energisation, showing the abilities of the Hilbert-based transforms.
Changing the Oxygen Mobility in Co/Ceria Catalysts by Ca Incorporation: Implications for Ethanol Steam Reforming (2009)

The effect of calcium doping on the performance of Co/CeO(2) catalysts in ethanol steam reforming was examined using various characterization techniques including CO temperature-programmed reduction, O(2) and CO pulse chemisorption, laser Raman spectroscopy, X-ray diffraction, isotopically labeled oxygen exchange, and diffuse reflectance infrared Fourier transform spectroscopy. Characterization results showed Ca incorporation to lead to oxygen vacancies and unit cell expansion in the ceria lattice. The creation of oxygen vacancies, in turn, enhanced the oxygen mobility in ceria-supported Co catalysts. Steady-state reaction studies showed increased TOF and higher H(2) yields over Co catalysts supported on Ca-doped ceria in ethanol steam reforming.
Gene expression‐based classifications of fibroadenomas and phyllodes tumours of the breast (2015)

Fibroepithelial tumors (FTs) of the breast are a heterogeneous group of lesions ranging from fibroadenomas (FAD) to phyllodes tumors (PT) (benign, borderline, malignant). Further understanding of their molecular features and classification might be of clinical value. In this study, we analysed the expression of 105 breast cancer-related genes, including the 50 genes of the PAM50 intrinsic subtype predictor and 12 genes of the Claudin-low subtype predictor, in a panel of 75 FTs (34 FADs, 5 juvenile FADs, 20 benign PTs, 5 borderline PTs and 11 malignant PTs) with clinical follow-up. In addition, we compared the expression profiles of FTs with those of 14 normal breast tissues and 49 primary invasive ductal carcinomas (IDCs). Our results revealed that the levels of expression of all breast cancer-related genes can discriminate the various groups of FTs, together with normal breast tissues and IDCs (False Discovery Rate < 5%). Among FTs, the levels expression of proliferation-related genes (e.g. CCNB1 and MKI67) and mesenchymal/epithelial-related (e.g. CLDN3 and EPCAM) genes were found to be most discriminative. As expected, FADs showed the highest and lowest expression of epithelial- and proliferation-related genes, respectively, whereas malignant PTs showed the opposite expression pattern. Interestingly, the overall profile of benign PTs was found more similar to FADs and normal breast tissues than the rest of tumours, including juvenile FADs. Within the dataset of IDCs and normal breast tissues, the vast majority of FADs, juvenile FADs, benign PTs and borderline PTs were identified as Normal-like by intrinsic breast cancer subtyping, whereas 7 (63.6%) and 3 (27.3%) malignant PTs were identified as Claudin-low and Basal-like, respectively. Finally, we observed that the previously described PAM50 risk of relapse prognostic score better predicted outcome in FTs than the morphological classification, even within PTs-only. Our results suggest that classification of FTs using gene expression-based data is feasible and might provide clinically useful biological and prognostic information.
Schottky barrier heights, carrier density, and negative electron affinity of hydrogen-terminated diamond (2010)

Chemical trends of Schottky barrier heights of ten kinds of metal contacts on hydrogen-terminated diamond (001) surfaces are estimated from the temperature dependence of their current-voltage characteristics. In addition to the measurements, the interface of the metal/hydrogen-terminated diamond is theoretically modeled including the carrier density of the surface conductive layer and the electron-affinity variation from the clean surface of the hydrogen-terminated diamond. Based on the model, a relation among the carrier density, the electron affinity variation, and the barrier heights are derived. The relation explains well experimental results of and other than the present work.
Characterization of root colonization profiles by a microcosm community of arbuscular mycorrhizal fungi using 25S rDNA‐targeted nested PCR (1998)

The aim of the present work was to study colonization patterns in roots by different arbuscular mycorrhizal fungi developing from a mixed community in soil. As different fungi cannot be distinguished with certainty in planta on the basis of fungal structures, taxon-discriminating molecular probes were developed. The 5' end of the large ribosomal subunit containing the variable domains D1 and D2 was amplified by PCR from Glomus mosseae (BEG12), G. intraradices (LPA8), Gigaspora rosea (BEG9) and Scutellospora castanea (BEG1) using newly designed eukaryote-specific primers. Sequences of the amplification products showed high interspecies variability and PCR taxon-discriminating primers were designed to distinguish between each of these four fungi. A nested PCR, using universal eukaryotic primers for the first amplification and taxon-discriminating primers for the second, was performed on individual trypan blue-stained mycorrhizal root fragments of onion and leek, and root colonization by four fungi inoculated together in a microcosm experiment was estimated. More than one fungus was detected in the majority of root fragments and all four fungi frequently co-existed within the same root fragment. Root colonization by G. mosseae and G. intraradices was similar from individual mixed inoculum, whilst the frequency of S. castanea and Gig. rosea increased in the presence of the two Glomus species, suggesting that synergistic interactions may exist between some arbuscular mycorrhizal fungi.
Pulse Wave Velocity, Intima Media Thickness, and Flow-mediated Dilatation in Patients with Normotensive Normoglycemic Inflammatory Bowel Disease (2015)

This study suggests that patients with IBD without traditional cardiovascular risk factors have increased risk of endothelial dysfunction and atherosclerosis.
Leber's Hereditary Optic Neuropathy-Gene Therapy: From Benchtop to Bedside (2010)

Leber's hereditary optic neuropathy (LHON) is a maternally transmitted disorder caused by point mutations in mitochondrial DNA (mtDNA). Most cases are due to mutations in genes encoding subunits of the NADH-ubiquinone oxidoreductase that is Complex I of the electron transport chain (ETC). These mutations are located at nucleotide positions 3460, 11778, or 14484 in the mitochondrial genome. The disease is characterized by apoplectic, bilateral, and severe visual loss. While the mutated mtDNA impairs generation of ATP by all mitochondria, there is only a selective loss of retinal ganglion cells and degeneration of optic nerve axons. Thus, blindness is typically permanent. Half of the men and 10% of females who harbor the pathogenic mtDNA mutation actually develop the phenotype. This incomplete penetrance and gender bias is not fully understood. Additional mitochondrial and/or nuclear genetic factors may modulate the phenotypic expression of LHON. In a population-based study, the mtDNA background of haplogroup J was associated with an inverse relationship of low-ATP generation and increased production of reactive oxygen species (ROS). Effective therapy for LHON has been elusive. In this paper, we describe the findings of pertinent published studies and discuss the controversies of potential strategies to ameliorate the disease.
CADERNO DE RESUMOS DO I CONGRESSO DE SAÚDE E SEGURANÇA DO TRABALHADOR E SUSTENTABILIDADE AMBIENTAL PARTE II - PERÍCIA MÉDICA ADMINISTRATIVA (2014)

Nesta  parte II do Caderno de Resumos, estao publicados os trabalhos apresentados no I CONCOSTSA que trataram da tematica Pericia Medica Administrativa.
Segmenting Webpage with Gomory-Hu Tree Based Clustering (2011)

We propose a novel web page segmentationalgorithm based on finding the Gomory-Hu tree in a planargraph. The algorithm firstly distills vision and structureinformation from a web page to construct a weightedundirected graph, whose vertices are the leaf nodes of theDOM tree and the edges represent the visible positionrelationship between vertices. Then it partitions the graphwith the Gomory-Hu tree based clustering algorithm.Experimental results show that, compared with VIPS andChakrabarti et al.’s graph theoretic algorithm, ouralgorithm improves upon the other two with much higherprecision and recall, and its running time is far lower thanthat of Chakrabarti et al.’s graph theoretic algorithm.
Parallel‐plate split‐conductor surface coil: Analysis and design (1988)

A split-conductor circular parallel-plate resonator with one end shorted to ground can be used to one's advantage as a surface coil for NMR imaging experiments. It can be easily constructed by a printed-circuit method and possesses a relatively high loaded Q with negligible frequency detuning. From the proposed equivalent circuit, an equation was derived that relates the self-resonance frequency of the resonator to the split distance measured from a reference point. An example of a 101-mm-diameter surface coil operating at 26 MHz for 31P in vivo spectroscopy is given to illustrate the concordance between calculated and experimental results. Complementary equations and formulas are also included to assist researchers in designing their own antennas to meet specific requirements.
The Emergent EU Policy on Asylum and Refugees (1999)

Abstract The Treaty of Amsterdam situates European asylum policy within a new institutional framework which is analysed with regard to the question how much progress has been achieved in this policy area. The assessment is based on an examination of asylum policy under the Maastricht Treaty and an analysis of its deficiencies. The output produced during the Maastricht era is evaluated by applying a measuring scale consisting of criteria such as efficiency, impact, democratic and judicial control, inner consistency, and respect for international obligations of member States. The analysis shows that the Maastricht Treaty neither provided a functioning nor an adequate framework for asylum policy on the European level. Instead of cautious cooperation of national approaches the policy area requires European harmonisation by issuing binding common texts which are interpreted in a unified manner. An important step in this direction will be taken by virtue of the Amsterdam Treaty which, however, also contains several potential obstacles to the harmonisation process. Furthermore, the increased access to binding legal instruments is not accompanied by an appropriate increase of democratic participation.
Discrete geodesic parallel coordinates (2019)

Geodesic parallel coordinates are orthogonal nets on surfaces where one of the two families of parameter lines are geodesic curves. We describe a discrete version of these special surface parameterizations and show that they are very useful for specific applications, most of which are related to the design and fabrication of surfaces in architecture. With the new discrete surface model, it is easy to control strip widths between neighboring geodesics. This facilitates tasks such as cladding a surface with strips of originally straight flat material or designing geodesic gridshells and timber rib shells. It is also possible to model nearly developable surfaces. These are characterized by geodesic strips with almost constant strip widths and are used for generating shapes that can be manufactured from materials which allow for some stretching or shrinking like felt, leather, or thin wooden boards. Most importantly, we show how to constrain the strip width parameters to model a class of intrinsically symmetric surfaces. These surfaces are isometric to surfaces of revolution and can be covered with doubly-curved panels that are produced with only a few molds when working with flexible materials like metal sheets.