gebhart/patrepeval huggingface dataset:
The theory and practice of adaptive reuse (1997)

article Free Access Share on The theory and practice of adaptive reuse Author: Paul G. Bassett Netron, Inc., Canada Netron, Inc., CanadaView Profile Authors Info & Claims ACM SIGSOFT Software Engineering NotesVolume 22Issue 3May 1997 pp 2–9https://doi.org/10.1145/258368.258371Published:01 May 1997Publication History 13citation1,615DownloadsMetricsTotal Citations13Total Downloads1,615Last 12 Months304Last 6 weeks60 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Effect of LED interlighting combined with overhead HPS light on fruit yield and quality of year-round sweet pepper in commercial greenhouse (2016)

Inter-lighting, applying supplemental light within crop canopy, has been shown to improve plant vertical light distribution and light use efficiency, with high-pressure sodium (HPS) lamps. However, it is not feasible on vegetables cultivated with the popular twin-row system (narrow row) used in major greenhouse vegetable production area in northern regions because of its high bulb temperature. Light-emitting diodes (LEDs) has low operating temperature and thus is potentially a good fit for inter-lighting. In this study, therefore, the effects of LED inter-lighting on sweet pepper growth, fruit yield and quality, and light and energy use efficiency were investigated in the commercial greenhouse. To optimize the production system with LED inter-lighting, different levels of top HPS lighting were also evaluated in the two experiments. Experiment one evaluated single row of LED inter-lighting module per twin-row (56.8 µmol m-2 s-1) without or with top HPS (78 µmol m-2 s-1). Experiment two evaluated the same LED inter-lighting module without or with the top HPS lamps at greater light intensity (155 µmol m-2 s-1). LED inter-lighting improved plant growth, fruit yield and quality compared to the top HPS treatment. Moreover, LED inter-lighting significantly increased fruit dry matter content and the content of health promoting compounds in fruits, including total phenolic content, total carotenoid content and antioxidant activities (ferric reducing antioxidant power assay and 2, 2-diphenyl-1-picrylhydrazyl assay), compared with the HPS treatments. As a result of LED inter-lighting more light reached the crop canopy with a higher efficiency of electricity to light conversion and the plants grown with LED inter-lighting and top HPS achieved higher yield and quality than that with the top HPS only in both experiments.
Online Delivery of Land Titles to Rural Farmers in Karnataka, India (2004)

The Bhoomi (meaning land) project for online delivery of land records in Karnataka, India- one of the country's 26 states- shows that making government services available to citizens in a transparent and efficient manner can empower them to challenge corrupt and arbitrary bureaucratic action. It also illustrates how well designed e-governance projects can be used to take discretion away from civil servants and provide benefits to rural farmers.
Holmium laser for benign prostatic hyperplasia (2008)

Holmium laser enucleation of the prostate is a safe procedure for treating not only patients without co-morbidities but also patients with urinary retention or who are on anticoagulants. Holmium laser enucleation of the prostate can be performed on prostates of all sizes with significantly less morbidity. Although holmium laser enucleation of the prostate represents a state-of-the-art procedure, a prolonged learning curve has still prevented the widespread adoption of this device in the urological community.
A Portable Airborne Scanning Lidar System for Ocean and Coastal Applications (2009)

Abstract A portable compact airborne scanning lidar system based on the Riegl LMS-Q240i has been developed and its functionality demonstrated for oceanographic and coastal measurements. Differential GPS (DGPS) and an inertial navigation system are synchronized with the lidar, resulting in vertical rms errors of less than 9 cm. Surveys with this airborne system are compared with ground-based DGPS surveys of fixed targets. Measurements of the southern California coastline and nearshore surface wave fields from 17 research flights between August 2007 and December 2008 are analyzed and discussed. The October 2007 landslide on Mt. Soledad in La Jolla, California, was documented by two of the flights. The topography, lagoon, reef, and surrounding wave field of Lady Elliot Island in Australia’s Great Barrier Reef were measured with the airborne scanning lidar system on eight research flights in April 2008. Applications of the system, including coastal topographic surveys, wave measurements, ship wake studies, and coral reef research, are presented and discussed.
Evaluation of Phosphatidylserine-Binding Peptides Targeting Apoptotic Cells (2012)

The inhibition or dysregulation of apoptosis plays an intimate role in the initiation and progression of cancer by confounding normal tissue homeostasis. We currently do not have a clinical method to assess apoptosis induced by cancer therapies. Phosphatidylserine (PS) is an attractive target for imaging apoptosis because it is on the exterior of the apoptotic cells and PS externalization is an early marker of apoptosis. PS-binding peptides are an attractive option for developing an imaging probe to detect apoptosis using positron emission tomography. In this study, four peptides were evaluated for PS-binding characteristics using a plate-based assay system, a liposome mimic of cell membrane PS presentation, and a cell assay of apoptosis. This work also describes two screening techniques to enable researchers to identify and optimize compounds that bind to PS. The results of our study indicate that all four peptides bind to PS and are specific to apoptotic cells. Two of the peptides in particular that have an additional cysteine residue are good potential candidates for development into imaging probes because they bind to PS with high affinity and specificity and they can be easily radiolabelled with (18)F.
The use of cognitive mapping technique in management research: theory and practice (2003)

The purpose of this article is to analyse the use of a qualitative approach using cognitive mapping techniques in the study of a decision‐making process. This study takes place in a public sector and in the context of a performance appraisal system (PAS). This is in line with recommendations by scholars and researchers to conduct a management research in a public service context (see Brown, 1999; Bissessar, 2000; Jabroun and Balakrishnan, 2000; O’Donnell and O’Brien, 2000; Redman, Snape and Thompson, 2000). This article also intends to elucidate and justify the methodological approach used, examine the assumptions underlying the use of a particular research design, and provide arguments for the preference of the methodology used. It is hoped that this will contribute to the understanding of the nature and validity of the research undertaken. This article begins by reviewing the theoretical issues of the research framework, the main features of the qualitative methodologies, and finally, the research method applied in this research is determined and justified.
An Intelligent Telecardiology System Using a Wearable and Wireless ECG to Detect Atrial Fibrillation (2010)

This study presents a novel wireless, ambulatory, real-time, and autoalarm intelligent telecardiology system to improve healthcare for cardiovascular disease, which is one of the most prevalent and costly health problems in the world. This system consists of a lightweight and power-saving wireless ECG device equipped with a built-in automatic warning expert system. This device is connected to a mobile and ubiquitous real-time display platform. The acquired ECG signals are instantaneously transmitted to mobile devices, such as netbooks or mobile phones through Bluetooth, and then, processed by the expert system. An alert signal is sent to the remote database server, which can be accessed by an Internet browser, once an abnormal ECG is detected. The current version of the expert system can identify five types of abnormal cardiac rhythms in real-time, including sinus tachycardia, sinus bradycardia, wide QRS complex, atrial fibrillation (AF), and cardiac asystole, which is very important for both the subjects who are being monitored and the healthcare personnel tracking cardiac-rhythm disorders. The proposed system also activates an emergency medical alarm system when problems occur. Clinical testing reveals that the proposed system is approximately 94% accurate, with high sensitivity, specificity, and positive prediction rates for ten normal subjects and 20 AF patients. We believe that in the future a business-card-like ECG device, accompanied with a mobile phone, can make universal cardiac protection service possible.
The TRP Superfamily of Cation Channels (2005)

The transient receptor potential (TRP) protein superfamily consists of a diverse group of cation channels that bear structural similarities to Drosophila TRP. TRP channels play important roles in nonexcitable cells; however, an emerging theme is that many TRP-related proteins are expressed predominantly in the nervous system and function in sensory physiology. The TRP superfamily is divided into seven subfamilies, the first of which is composed of the "classical" TRPs" (TRPC subfamily). Some TRPCs may be store-operated channels, whereas others appear to be activated by production of diacylglycerol or regulated through an exocytotic mechanism. Many members of a second subfamily (TRPV) function in sensory physiology and respond to heat, changes in osmolarity, odorants, and mechanical stimuli. Two members of the TRPM family function in sensory perception and three TRPM proteins are chanzymes, which contain C-terminal enzyme domains. The fourth and fifth subfamilies, TRPN and TRPA, include proteins with many ankyrin repeats. TRPN proteins function in mechanotransduction, whereas TRPA1 is activated by noxious cold and is also required for the auditory response. In addition to these five closely related TRP subfamilies, which comprise the Group 1 TRPs, members of the two Group 2 TRP subfamilies, TRPP and TRPML, are distantly related to the group 1 TRPs. Mutations in the founding members of these latter subfamilies are responsible for human diseases. Each of the TRP subfamilies are represented by members in worms and flies, providing the potential for using genetic approaches to characterize the normal functions and activation mechanisms of these channels.
Reliability of the CMT neuropathy score (second version) in Charcot‐Marie‐Tooth disease (2011)

The Charcot-Marie-Tooth neuropathy score (CMTNS) is a reliable and valid composite score comprising symptoms, signs, and neurophysiological tests, which has been used in natural history studies of CMT1A and CMT1X and as an outcome measure in treatment trials of CMT1A. Following an international workshop on outcome measures in Charcot-Marie-Tooth disease (CMT), the CMTNS was modified to attempt to reduce floor and ceiling effects and to standardize patient assessment, aiming to improve its sensitivity for detecting change over time and the effect of an intervention. After agreeing on the modifications made to the CMTNS (CMTNS2), three examiners evaluated 16 patients to determine inter-rater reliability; one examiner evaluated 18 patients twice within 8 weeks to determine intra-rater reliability. Three examiners evaluated 63 patients using the CMTNS and the CMTNS2 to determine how the modifications altered scoring. For inter- and intra-rater reliability, intra-class correlation coefficients (ICCs) were ≥0.96 for the CMT symptom score and the CMT examination score. There were small but significant differences in some of the individual components of the CMTNS compared with the CMTNS2, mainly in the components that had been modified the most. A longitudinal study is in progress to determine whether the CMTNS2 is more sensitive than the CMTNS for detecting change over time.
Tissue distribution and kinetic characteristics of rat steroid 5 alpha-reductase isozymes. Evidence for distinct physiological functions. (1992)

The enzyme steroid 5 alpha-reductase (5 alpha-reductase) catalyzes the reduction of delta 4,5 double bonds in a variety of substrates and is thought to play both catabolic and anabolic roles in steroid hormone metabolism. Here, we describe the isolation and characterization of a cDNA encoding the rat type 2 isozyme of 5 alpha-reductase and compare the kinetic properties and tissue-specific expression patterns of this isozyme with those of the type 1 isozyme. The type 2 isozyme has apparent Km values in the nanomolar range for steroid substrates, whereas the type 1 isozyme has micromolar affinities. The isozymes differ in their inhibition by various 4-azasteroids with the type 2 isozyme showing exquisite sensitivity (Ki = 40 pM) to 21,21-pentamethylene-4-aza-5 alpha-pregn-1-ene-3,20-dione. Messenger RNAs encoding the type 2 isozyme are more abundant than type 1 mRNAs in most male reproductive tissues, whereas the type 1 mRNAs predominate in peripheral tissues. Both 5 alpha-reductase mRNAs are more efficiently induced by dihydrotestosterone than by testosterone in the regenerating prostate. The differences in substrate affinities and tissue distributions of the 5 alpha-reductase isozymes suggest that type 2 plays an anabolic role and type 1 a catabolic role in the metabolism of androgens and other steroid hormones.
Characterization of TbPDE2A, a Novel Cyclic Nucleotide-specific Phosphodiesterase from the Protozoan Parasite Trypanosoma brucei (2001)

This study reports the identification and characterization of a cAMP-specific phosphodiesterase from the parasitic hemoflagellate Trypanosoma brucei. TbPDE2A is a class I phosphodiesterase. Its catalytic domain exhibits 30-40% sequence identity with those of all 11 mammalian phosphodiesterase (PDE) families, as well as with PDE2 from Saccharomyces cerevisiae, dunce from Drosophila melanogaster, and regA from Dictyostelium discoideum. The overall structure of TbPDE2A resembles that of human PDE11A in that its N-terminal region contains a single GAF domain. This domain is very similar to those of the mammalian PDE2, -5, -6, -10, and -11, where it constitutes a potential cGMP binding site. TbPDE2A can be expressed in S. cerevisiae, and it complements an S. cerevisiae PDE deletion strain. Recombinant TbPDE2A is specific for cAMP, with a K(m) of approximately 2 micrometer. It is entirely resistant to the nonselective PDE inhibitor 3-isobutyl-1-methylxanthine, but it is sensitive to trequinsin, dipyridamole, sildenafil, and ethaverine with IC(50) values of 5.4, 5.9, 9.4, and 14.2 micrometer, respectively. All four compounds inhibit proliferation of bloodstream form trypanosomes in culture, indicating that TbPDE2A is an essential enzyme.
Low‐Pressure chemical vapour deposition of tantalum pentoxide films for ulsi devices using tantalum pentaethoxide as precursor (1992)

Abstract A laminar flow low‐pressure chemical vapour deposition (LPCVD) system (LAM Integrity TM ) has been used to deposit tantalum pentoxide (Ta 2 O 5 ) from Ta(OEt) 5 films in the presence of oxygen (O 2 ) at 470 °C at a typical deposition rate of 4 nm min −1 . Uniformities of <1.5% (SD 1σ) over a 150 mm silicon substrate were obtained. The layers were annealed under different conditions. It was discovered that the films did not change their stoichiometry as determined by Rutherford backscattering (RBS). The as‐deposited films were amorphous but became crystalline (β‐Ta 2 O 5 ) at temperatures > 700 °C. The transmission electron microscopy (TEM) results on crystallisation behaviour were supported by X‐ray diffraction data. The electrical properties of the Ta 2 O 5 films have been characterised using MIS (metal/insulator/silicon) capacitor structures. Leakage values of <10 −6 A cm −2 at 6 MV cm −1 equivalent applied electric field and breakdown strengths of >7 MV cm −1 at 1.6 μA were obtained for annealed layers. Compound dielectric constants (native silicon oxide thickness of about 2.5 nm plus Ta 2 O 5 of various thicknesses) between 14 and >30 have been measured. The electrical properties reveal the potential use of Ta 2 O 5 as a storage capacitor dielectric in 64 and 256 Mbit DRAM (dynamic random access memory) devices.
Epidermal growth factor receptor (EGFR) gene and protein expression in renal cell carcinoma (RCC) (2006)

A84 The epidermal growth factor receptor (EGFR) tyrosine kinase is over-expressed in numerous tumor types, where in some instances the level of expression correlates with disease outcome and tumor response to targeted EGFR therapies. Although immunohistochemistry (IHC) is the most frequently used diagnostic method to assess the over-expression of EGFR protein, other more quantitative methods such as real-time polymerase chain reaction q(RT)PCR should be considered. To this end, we compared q(RT)PCR measurements of EGFR in renal cell carcinoma (RCC) tumors that had been previously stained and scored by IHC using the DAKO EGFR PharmDx Kit to determine whether this assay provides an accurate and objective alternative for the determination of EGFR status.Methods: Forty RCC tumors receiving a semi-quantitative IHC score of 0, 1+, 2+ and 3+ were evaluated using TaqMan technology. Four housekeeping genes were used to normalize the EGFR measurements and reduce variability.Results: A statistically significant association (p-value 0.0002) between IHC and q(RT)PCR measurements for EGFR was observed. Conclusion: The data show that the results obtained for gene expression by q(RT) PCR correlate well with results obtained by IHC. These data suggest that q(RT)PCR analysis is a viable alternative for assessing the expression of EGFR in RCC. Further, the greater dynamic range of measurement and quantitative nature of q(RT)PCR suggest that a combined IHC and real-time PCR approach for the determination of EGFR status in RCC patients may be a more effective and efficient strategy for patient stratification than IHC alone.
Functionalization of thiazoles. Selectivity in the reactions of 2-(dimethylamino)-1,3-thiazoles with electrophiles: formation of Michael-type adducts and thiazolium salts (1981)

The reactions of 2-(dimethylamino)-1,3-thiazoles with compounds cntaining an electron-poor double or triple bond are described.
Programming colloidal phase transitions with DNA strand displacement (2015)

DNA-grafted nanoparticles have been called "programmable atom-equivalents": Like atoms, they form three-dimensional crystals, but unlike atoms, the particles themselves carry information (the sequences of the grafted strands) that can be used to "program" the equilibrium crystal structures. We show that the programmability of these colloids can be generalized to the full temperature-dependent phase diagram, not just the crystal structures themselves. We add information to the buffer in the form of soluble DNA strands designed to compete with the grafted strands through strand displacement. Using only two displacement reactions, we program phase behavior not found in atomic systems or other DNA-grafted colloids, including arbitrarily wide gas-solid coexistence, reentrant melting, and even reversible transitions between distinct crystal phases.
Localization and regulation of bacteriophage Mu promoters (1989)

Mu promoters active during the lytic cycle were located by isolating RNA at various times after induction of Mu prophages, radiolabeling it by capping in vitro, and hybridizing it to Mu DNA fragments on Southern blots. Signals were detected from four new promoters in addition to the previously characterized Pe (early), PcM (repressor), and Pmom (late) promoters. A major signal upstream of C was first observed at 12 min and intensified thereafter with RNA from cts and C amber but not replication-defective prophages; these characteristics indicate that this signal arises from a middle promoter, which we designate Pm. With 20- and 40-min RNA, four additional major signals originated in the C-lys, F-G-I, N-P, and com-mom regions. These signals were missing with RNA from C amber and replication-defective prophages and therefore reflected the activity of late promoters, one of which we presume was Pmom. Uninduced lysogens showed weak signals from five regions, one from the early regulatory region, three between genes B and lys, and one near the late genes K, L, and M. The first of these probably resulted from PcM activity; the others remain to be identified.
Anti-inflammatory Sesquiterpenoids from a Sponge-Derived Fungus <i>Acremonium</i> sp. (2009)

In the course of our search for bioactive metabolites from a sponge-derived fungus Acremonium sp., new sesquiterpenoids (1-4) were isolated along with known derivatives by bioactivity-guided fractionation. The unique cyclic skeleton of compounds 2 and 3 is unprecedented. The absolute configurations were determined by modified Mosher's method and CD spectroscopy, along with comparison of (1)H and (13)C NMR spectroscopic data and specific optical rotation values with those reported. The anti-inflammatory activity of the isolated compounds (1, 5, 7-13) was evaluated by measuring their inhibitory effects on the production of pro-inflammatory mediators (NO, IL-6, and TNF-alpha) in RAW 264.7 murine macrophage cells. Among the compounds tested, compounds 7 and 9 significantly inhibited the production of NO and TNF-alpha at the concentration of 100 microM, while compounds 11 and 12 showed selective inhibition of NO production at the same concentration.
Electrochemical investigation of kinetic and thermodynamic aspects of oxidation and reduction of mononuclear and binuclear rhodium dithiocarbamate and diselenocarbamate complexes (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectrochemical investigation of kinetic and thermodynamic aspects of oxidation and reduction of mononuclear and binuclear rhodium dithiocarbamate and diselenocarbamate complexesAlan M. Bond, Ray Colton, and Desma R. MannCite this: Inorg. Chem. 1989, 28, 1, 54–59Publication Date (Print):January 1, 1989Publication History Published online1 May 2002Published inissue 1 January 1989https://pubs.acs.org/doi/10.1021/ic00300a013https://doi.org/10.1021/ic00300a013research-articleACS PublicationsRequest reuse permissionsArticle Views92Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts