gebhart/patrepeval huggingface dataset:
Role of galanin in stimulation of pituitary luteinizing hormone secretion as revealed by a specific receptor antagonist, galantide (1994)

In this study, a specific galanin (GAL) receptor antagonist, galantide, was employed to evaluate the role of endogenous GAL in episodic basal and phasic LH release in rats. To assess the specificity of galantide, a series of experiments was performed. In the first experiment, we observed that administration of GAL (0.62 nm) intracerebroventricularly (icv) in ovarian steroid-primed ovariectomized (ovx) rats rapidly increased plasma LH levels between 10-30 min, and prior injection of galantide icv (5 nm) blocked the GAL-induced LH release. In the second experiment, galantide inhibited the GAL-evoked in vitro release of LHRH from the median eminence-arcuate nucleus (ME-ARC) of ovarian steroid-primed ovx rats. In addition, galantide on its own significantly decreased the basal efflux of LHRH from the ME-ARC of similarly treated rats, thereby suggesting that even the basal LHRH secretion may be a GAL-dependent event. In the third experiment, the effects of galantide on the phasic LH surge elicited by progesterone (P) in estradiol benzoate-primed ovx rats and that occurring spontaneously on proestrus were examined. Ovx rats bearing icv cannulae were primed with estradiol benzoate (30 micrograms/rat, sc) and 2 days later received a P (2 mg/rat, sc) injection at 1000 h to evoke a LH surge in the afternoon. Galantide (1 or 5 nm) in 3 microliters saline or saline was injected icv at 1300, 1400, and 1500 h. The results showed that the two dosages of galantide suppressed the LH surge in the afternoon. On the other hand, only a very high dose of galantide (15 nm) injected iv at 1300, 1400, and 1500 h blunted the P-induced LH hypersecretion. Central injections of galantide (1 or 5 nm) at 1300, 1400, and 1500 h on proestrus also inhibited the preovulatory LH surge and significantly reduced the numbers of rats ovulating the following day. In the final experiment, the role of GAL receptors in modulation of episodic LH release was analyzed in ovx rats. The results showed that an injection of galantide (5 nm, icv) significantly decreased both the mean LH levels and the amplitude of LH episodes during the 3-h observation period. Cumulatively, these results show that normally GAL stimulates LHRH release by activation of a specific receptor located in the ME-ARC, and that GAL may be a key excitatory signal in the hypothalamic neural circuitry involved in the regulation of basal episodic and phasic LHRH secretion in cycling female rats.
Rapid <sup>1</sup>H NMR determination of hydrogen peroxide in cosmetic products and chemical reagents (2016)

A methodology utilizing <sup>1</sup>H NMR spectroscopy has been developed to measure the concentration of hydrogen peroxide in hair sprays, nail treatments, hydrogen peroxide solutions for disinfection and chemical reagents.
[P(MeNCH<sub>2</sub>CH<sub>2</sub>)<sub>3</sub>N] as a Superior Catalyst for the Conversion of Isocyanates to Isocyanurates (1993)

The unusually strong Lewis basicity of the P atom and the ability to form transannular PN interactions of various strengths account for the high catalytic activity of [P(MeNCH2CH2)3N] in the title reaction, a key step of which is shown on the right. Thus a 97% yield of triphenyl isocyanurate (Ar = C6H5) was obtained in 3 min, and a 99% yield of tri-para-methoxyphenyl isocyanurate (Ar = 4-MeOC6H4) in 8 min.
Voxel carving for specular surfaces (2003)

We present an novel algorithm that reconstructs voxels of a general 3D specular surface from multiple images of a calibrated camera. A calibrated scene (i.e. points whose 3D coordinates are known) is reflected by the unknown specular surface onto the image plane of the camera. For every viewpoint, surface normals are associated to the voxels traversed by each projection ray formed by the reflection of a scene point. A decision process then discards voxels whose associated surface normals are not consistent with one another. The output of the algorithm is a collection of voxels and surface normals in 3D space, whose quality and size depend on user-set thresholds. The method has been tested on synthetic and real images. Visual and quantified experimental results are presented.
Microcoria due to first duplication of 13q32.1 including the GPR180 gene and maternal mosaicism (2020)

Congenital microcoria (MCOR) is an eye anomaly characterized by a pupil with diameter below 2 mm, and is caused by underdevelopment or absence of the dilator muscle of the pupil. Two types have been described: a recessive, syndromic (Pierson syndrome OMIM 609049) and a dominant, isolated form (MCOR syndrome OMIM 156600). Fares-Taie and colleagues described inherited microdeletions in chromosome band 13q32.1 segregating with dominant microcoria in several families. The GPR180 gene is located within the smallest commonly deleted region and encodes a G protein-coupled receptor involved in smooth muscle cells growth. We here describe a patient with isolated, non-syndromic MCOR. The patient presented with a blue iris and small pupils, non-reactive to cycloplegic agents. Her mother had a milder ocular phenotype, namely a blue iris with hypoplastic crypts and mild myopia. We present a detailed clinical examination and follow up. DNA from the index patient was analyzed for the presence of chromosomal imbalances using molecular karyotyping. The genetic test revealed a small duplication of chromosome band 13q32.1. The duplication affected a 289 kb region, encompassing 11 genes including GPR180. Interestingly, the patient displays only MCOR in contrast to patients with the reciprocal deletion who present with MCOR and iridocorneal angle dysgenesis. This genetic anomaly was inherited from the mother who carries the duplication in mosaic form, which should be considered when offering genetic counselling. In summary, we describe the first 13q32.1 duplication encompassing GPR180 associated with MCOR.
DOMINANT EFFECT OF TRANSFUSIONS ON KIDNEY GRAFT SURVIVAL (1980)

The number of pretransplant blood transfusions influences the graft survival of cadaver kidney transplants more than HLA-A and B matching, preformed lymphocytotoxic antibodies, or center variation. At 1 year the graft survival rate in patients with more than 20 packed cells transfusions was over 30% higher than that in nontransfused recipients (75 +/- 5% versus 41 +/- 2%, P less than 0.0001). Recipients with on packed cell transfusion had a 59 +/- 5% 1-year graft survival rate. Frozen blood and any transfusions given at the time of surgery were relatively ineffective. Pretransplant pregnancies had no significant effect on graft outcome. The improvement effect of transfusions was significant in each of the last four calendar years (1975, P less than 0.001; 1976, P less than 0.01; 1977, P less than 0.0001; 1978, P less than 0.0001). Yet, the percentage of nontransfused recipients has remained almost unchanged over the years. A preliminary survey of transplants done from January to April 1979 showed that one-third of the recipients had not been transfused. A change in transfusion policy is indicated to improve the results of cadaver kidney transplantation.
Study of applying contactless power transmission system to battery charge (2009)

Contactless power transmission system with the advantages of safety and convenience has been applied to daily supplies. However, general contactless power transmission charger cannot control the current cause there is no charge controller in secondary side and the severe limitation between primary and secondary sides of the battery charger cause difficulty to design. This study provides the charge controller with half-bridge inverter and E-Type core as coupling converter in primary side; A Zeta DC converter is utilized to achieve the outcome of charge with constant voltage and to increase the charging distance between primary and secondary sides. To verify the feasibility of contactless power transmission system, the study completes the contactless charger with the output power of 30W. The result shows that the overall system efficiency is 57.8 % with 150 V/0.35A input and 15.2 V/2 A output.
Arabinoxylan Gels:  Impact of the Feruloylation Degree on Their Structure and Properties (2004)

Arabinoxylan (AX) samples of decreasing ferulic acid (FA) contents were chemically prepared from water-extractable wheat arabinoxylans without affecting their other structural properties. Gels were obtained from these partially feruloylated WEAX (PF-WEAX) by enzymatic covalent cross-linking of FA leading to the formation of diferulic (di-FA) and tri-ferulic acid (tri-FA). WEAX gelling ability was found related to the WEAX FA content whereas the gel structure and properties depended on the density of newly formed covalent cross-links. FA content of WEAX ranging from 1.4 to 2.3 microg/mg AX gave gels with di-FA cross-links contents from 0.20 to 0.43 microg/mg AX and G' values from 5 to 44 Pa. For WEAX gels with initial FA contents from 1.6 to 2.3 microg/mg AX, average mesh size ranging from 331 to 263 nm were calculated from swelling experiments. Cross-linking densities of gels, determined from swelling experiments, were higher than those that could be theoretically estimated from the di-FA and tri-FA content of WEAX gels. This result suggests that, in addition to di-FA and tri-FA, higher ferulate cross-linking and physical entanglements would contribute to the final WEAX gel structure.
A 10-bit high-speed low-power CMOS D/A converter in 0.2 mm/sup 2/ (2002)

This paper describes design and implementation of a 10-bit current steering CMOS D/A converter for a direct digital synthesizer. A very small circuit area is achieved by constructing the binary weighted currents using two sized unit current sources. This structure also leads to low power consumption since no decoding logic is needed. The glitch energy is reduced by using properly overlapped and amplitude limited steering signals for the differential current switches. The measured DNL is 0.43 LSB and INL 0.35 LSB. According to simulations the circuit achieves >60 dBc SFDR at 250 MS/s sampling rate with power dissipation of 17 mW@3.3 V. The circuit is implemented in 0.5 /spl mu/m CMOS technology.
Adaptive Post-Filtering of ADPCM Speech (1981)

We show that the quality of adaptive differential PCM (ADPCM) speech can be significantly improved by passing it through a reconstruction low-pass filter that is matched to an appropriately defined short-time speech cutoff frequency. Practically, the adaptive procedure involves switching the decoder output into one of a bank of N low-pass filters whose cutoff frequencies span the expected range of input speech bandwidth. For the case of equally spaced filter cutoffs, and with uniform probability density function models for the quantization noise spectrum and the cutoff frequency, more than one-half of the maximum adaptive filtering gain is realisable by a bank of four filters. Computer simulations of l6- and 24-kilobit/s ADPCM coders indicate that perceived quality gains are in fact greater than what is indicated by an analytically predicted objective gain of 2 6 dB.
A virtual simulation package for Embedded System training and education (2009)

Laboratory assignments for Embedded System courses are usually performed with a hardware-based training kit that equipped with an embedded system board, software development tools, and optionally an emulator for debugging. Using the hardware-based kits has some demerits such as high initial setup cost, burdensome maintenance, lacks of adaptability to industry evolution, and restricted educational outcomes. This paper deals with a simulation-based education package for laboratory works in Embedded System courses. The package uses the ARM's ARMulator environment that can simulate a simple ARM architecture board in cycle-level. We extended the ARMulator environment into a powerful one that can simulate an embedded system board by implementing various hardware IP models and peripheral simulation programs. The developed education package can be used to train students in Embedded System courses for topics such as assembly and C/C++ programming, processor architecture, memory system handling, peripheral control, system performance, real-time operating system, and development environment with overcoming the demerits of hardware-based kits.
The synthesis and biological activity of lipophilic derivatives of bicine conjugated with<i>N</i><sup>3</sup>-(4-methoxyfumaroyl)-<scp>L</scp>-2,3-diaminopropanoic acid (FMDP)—an inhibitor of glucosamine-6-phosphate synthase (2011)

A series of bis-N,N-(2-hydroxyethyl)glycine (bicine) derivatives, conjugated with an inhibitor of glucosamine-6-phosphate synthase, have been synthesized and their lipophilic and antifungal properties have been tested. The obtained compounds demonstrated higher lipophilicity than free inhibitor (FMDP) and, in consequence, an increased potential to cross the cytoplasmic membrane. All the tested compounds show better antifungal activity than parent compound.
Supervised Machine-Learning-Based Determination of Three-Dimensional Structure of Metallic Nanoparticles (2017)

Tracking the structure of heterogeneous catalysts under operando conditions remains a challenge due to the paucity of experimental techniques that can provide atomic-level information for catalytic metal species. Here we report on the use of X-ray absorption near-edge structure (XANES) spectroscopy and supervised machine learning (SML) for refining the 3D geometry of metal catalysts. SML is used to unravel the hidden relationship between the XANES features and catalyst geometry. To train our SML method, we rely on ab initio XANES simulations. Our approach allows one to solve the structure of a metal catalyst from its experimental XANES, as demonstrated here by reconstructing the average size, shape, and morphology of well-defined platinum nanoparticles. This method is applicable to the determination of the nanoparticle structure in operando studies and can be generalized to other nanoscale systems. It also allows on-the-fly XANES analysis and is a promising approach for high-throughput and time-dependent studies.
Development and Analysis of the Naval Facilities Engineering Service Center Aviation Engine Simulation Facility. (1996)

Abstract : This report documents the development of the Naval Facilities Engineering Service Center (NFESC) Aviation Engine Simulation Facility (AESF). The objective of this effort was to develop a facility which can repetitively expose candidate pavement specimens to convective heat transfer rates equal to those which pavements at operational airfields experience due to jet exhaust impingement. Damage of concrete pavements has become a chronic problem at Navy, Marine Corps and Air Force bases. The damage is due to impingement of vertically directed jet exhaust flow from auxiliary power unit (APU) engines of the F/A. 18 and B-1 aircraft, and from the main propulsion engines of the AV-8B aircraft during vertical takeoff and landing. The main component of the AESF is a burner and nozzle assembly in which there is combustion of natural gas. By controlling the combustion chamber pressure and temperature, along with the nozzle diameter and distance from the specimen, the AESF can impose convective heating rates on the specimen that equal the heating rates imposed on operational airfields by full scale engines. The experimental data validated the applicability of the exhaust simulation. Specimens can be repetitively exposed to the simulated exhaust flow to evaluate their performance under the simulated exhaust conditions.
A study of finger vein biometric for personal identification (2008)

Finger vein authentication can be a leading biometric technology nowadays in terms of security and convenience, since it introduces the features inside the human body. An image of a finger captured by the web camera under the IR light transmission contains not only the vein pattern itself, but also shade produced by various thickness of the finger muscles, bones, and tissue networks surrounding the vein. In this paper, we introduce preliminary process to enhance the image quality worsened by light effect and noise produced by the web camera, then segment the vein pattern by using adaptive threshold method and matched them using improved template matching. The experimental result shows that even the image quality is not good, as long as our veins are clear and also with some appropriate process it still can be used as the means of personal identification. Hence it still can achieve up to 100% identification accuracy.
Machine translation by interaction between paraphraser and transfer (2002)

A machine translation model has been proposed where an input is translated through both source-language and target-language paraphrasing processes. We have implemented our prototype model for the Japanese-Chinese language pair. This paper. describes our core idea of translation, where a source language paraphraser and a language transfer cooperates in translation by exchanging information about the source input.
Pathogen Reduction Technologies: The Best Solution for Safer Blood? (2013)

Although it is generally accepted that blood has never been safer than today, transfusion-associated side effects, particularly infective, still occur. Unlike screening strategies, pathogen reduction technologies offer a new approach to increase blood safety by actively/directly targeting possible, also emerging pathogens or donor leukocytes. Advanced technologies for cellular blood products like the psoralen-based INTERCEPT BLOOD SYSTEM or the riboflavin-based Mirasol pathogen reduction technology system have extensively been examined and are on the way to enter the blood bank routine. However, as with any medical treatment, the transfusion of pathogen reduced blood products is not completely risk-free. Due to possible impairment of the treated blood cells the transfusion success is significantly lower as compared to untreated blood products. Long-term side effects concerning the photosensitizers and their photoproducts still remain a matter of debate. This paper outlines current pathogen reduction technologies but also focuses on ethical concerns associated with the employment of these techniques.
Charge Oscillation Controlled Molecular Excitation (2013)

The direct manipulation of charge oscillations has emerged as a new perspective in chemical reaction control. Here, we demonstrate, in a joint experimental and theoretical study, that the electron dynamics of a molecule is efficiently steered by controlling the interplay of a driving femtosecond laser pulse with the photoinduced charge oscillation. These oscillations have a typical Bohr period of around 1 fs for valence electrons; therefore, control has to be exerted on a shorter time scale. Specifically, we show how precision pulse shaping is used to manipulate the coupled electron and nuclear dynamics in order to address different bound electronic target states in a molecule. We present a strong-field coherent control mechanism which is understood in terms of a simple classical picture and at the same time verified by solving the time-dependent Schrödinger equation. This mechanism is universally applicable and opens a wide spectrum of applications in the reaction control of complex systems.
Avian Influenza Virus (2008)

Avian Influenza Virus Table of Contents 1. A brief introduction to avian influenza virus Erica Spackman 2. Avian Influenza Virus Sample Types, Collection, and Handling Mary-Lea Killian 3. Avian influenza virus RNA extraction from tissue and swab material Erica Spackman and David L. Suarez 4. Type-A Influenza Virus Detection and Quantitation by Real-time RT-PCR Erica Spackman and David L. Suarez 5. Detection and Identification of the H5 Hemagglutinin subtype by Real-time RT-PCR Erica Spackman and David L. Suarez 6. Avian influenza virus isolation and propagation in chicken eggs Peter R. Woolcock 7. Hemagglutination Assay for Avian Influenza Virus Mary-Lea Killian 8. Hemagglutination-Inhibition Test for Avian Influenza Virus Subtype Identification and the Detection and Quantititation of Serum Antibodies to Avian Influenza Virus Janice C. Pedersen 9. Neuraminidase-Inhibition Assay for the Identification of Influenza A Virus Neuraminidase Subtype or Neuraminidase Antibody Specificity Janice C. Pedersen 10. Immunohistochemical Staining for the Detection of Avian Influenza Virus in Tissues Mary Pantin-Jackwood 11. Wild bird Surveillance for Avian Influenza Virus Justin D. Brown and David E. Stallknecht 12. Reverse Genetics of Avian Influenza Virus Chang-Won Lee and David L. Suarez 13. Evaluating the Cell Mediated Immune Response of Avian Species to Avian Influenza Viruses Darrell R. Kapczynski 14. Measurment of avian cytokines with real-time RT-PCR following infection with avian influenza virus Darrell R. Kapczynski and Michael H. Kogut
Novel chelated biscarborane transition metal complexes formed through carbon-metal .sigma. bonds (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNovel chelated biscarborane transition metal complexes formed through carbon-metal .sigma. bondsDavid A. Owen and M. Frederick HawthorneCite this: J. Am. Chem. Soc. 1970, 92, 10, 3194–3196Publication Date (Print):May 1, 1970Publication History Published online1 May 2002Published inissue 1 May 1970https://pubs.acs.org/doi/10.1021/ja00713a051https://doi.org/10.1021/ja00713a051research-articleACS PublicationsRequest reuse permissionsArticle Views172Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Wolbachia endosymbionts and human disease control (2014)

Most human filarial nematode parasites and arthropods are hosts for a bacterial endosymbiont, Wolbachia. In filaria, Wolbachia are required for normal development, fertility and survival, whereas in arthropods, they are largely parasitic and can influence development and reproduction, but are generally not required for host survival. Due to their obligate nature in filarial parasites, Wolbachia have been a target for drug discovery initiatives using several approaches including diversity and focused library screening and genomic sequence analysis. In vitro and in vivo anti-Wolbachia antibiotic treatments have been shown to have adulticidal activity, a long sought goal of filarial parasite drug discovery. In mosquitoes, it has been shown that the presence of Wolbachia can inhibit the transmission of certain viruses, such as Dengue, Chikungunya, Yellow Fever, West Nile, as well as the infectivity of the malaria-causing protozoan, Plasmodium and filarial nematodes. Furthermore, Wolbachia can cause a form of conditional sterility that can be used to suppress populations of mosquitoes and additional medically important insects. Thus Wolbachia, a pandemic endosymbiont offers great potential for elimination of a wide-variety of devastating human diseases.