gebhart/patrepeval huggingface dataset:
Super-FEC Codes for 40/100 Gbps Networking (2012)

This letter first introduces a simple approach to evaluate performance bounds at very low bit-error-rate range for binary pseudo-product codes and true-product codes. Then it presents a super-product BCH code together with a novel decoding technique. It is shown that the proposed code can achieve near-Shannon limit performance with low decoding complexity.
Efficient Range Query Processing in Peer-to-Peer Systems (2008)

With the increasing popularity of the peer-to-peer (P2P) computing paradigm, many general range query schemes for distributed hash table (DHT)-based P2P systems have been proposed in recent years. Although those schemes can provide range query capability without modifying the underlying DHTs, they have the query delay depending on both the scale of the system and the size of the query space or the specific query, and thus cannot guarantee to return the query results in a bounded delay. In this paper, we propose Armada, an efficient range query processing scheme to support delay-bounded single-attribute and multiple-attribute range queries. It is the first delay-bounded general range query scheme on constant-degree DHTs, and can return the results for any range query within 2logN hops in a P2P system with N peers. Results of analysis and simulations show that the average delay in Armada is less than logN, and the average message cost of single-attribute range queries is about logN+2n 2 (n is the number of peers that intersect with the query). These results are very close to the lower bounds on delay and message cost of range queries over constant-degree DHTs.
Design flow enhancements for DNA arrays (2004)

DNA probe arrays have recently emerged as one of the core genomic technologies. Exploiting analogies between manufacturing processes for DNA arrays and for VLSI chips, we demonstrate the potential for transfer of methodologies from the 40-year old field of electronic design automation to the newer DNA array design field. Our main contributions are the following. (1) We give a new design flow for DNA arrays which enhances current methodologies by adding flow-awareness to each optimization step and introducing feedback loops. (2) We propose solution methods for new formulations integrating multiple design steps, including probe selection, placement, and embedding. (3) We give results of a comprehensive experimental study showing that significant improvements in solution quality can be achieved by using the enhanced methodologies.
lin-31, a Caenorhabditis elegans HNF-3/fork head transcription factor homolog, specifies three alternative cell fates in vulval development. (1993)

Cell-cell signaling controls the specification of vulval cell fates in Caenorhabditis elegans. Although previous studies have identified genes that function at early steps in the signaling pathway, the late steps are not well understood. Here, we begin to characterize those late events by showing that the lin-31 gene acts near the end of the vulval signaling pathway. We show that lin-31 acts downstream of the ras homolog let-60 and that lin-31 encodes a member of the HNF-3/fork head family of DNA-binding transcription factors. lin-31 regulates how vulval precursor cells choose their fate; in lin-31 mutants, these cells do not properly choose which fate to express and therefore adopt any one of the three possible vulval cell fates in a deregulated fashion. This interesting mutant phenotype suggests mechanisms for how vulval cell fates become determined.
Reduction of acoustic noise in FDB spindle motors by using drive technology (2003)

In the operation of fluid-dynamic-bearing (FDB) motors, the acoustic noise caused by the electromagnetic forces takes a big ratio in the noise level. The authors analyze the relationship between the acoustic noise frequency, harmonic current, and harmonic field, and propose a drive mode for reducing the acoustic noise of the FDB motors. The drive mode can also reduce the copper loss in the motor operation.
Stille Reactions Catalytic in Tin:  A “Sn−F” Route for Intermolecular and Intramolecular Couplings (2005)

Polymethylhydrosiloxane (PMHS) made hypercoordinate by KF(aq) allows Me(3)SnH to be recycled during a Pd(0)-catalyzed hydrostannation/Stille cascade. Starting with a variety of alkynes, in situ vinyltin formation is followed by Stille reaction with aryl, styryl, benzyl, or vinyl electrophiles present in the reaction mixture. Both inter- and intramolecular versions of the process are possible with tin loads of approximately 6 mol %. Regeneration of the organotin hydride is believed to proceed through a Me(3)SnF intermediate. Given the aggregated nature of organotin fluorides and the ability to use these organotins in substoichiometric quantities, the hazards and purification problems associated with the removal of organotin wastes from reaction mixtures are minimized.
A new microwave discriminator (2004)

This paper presents the theory and experiment of a hybrid microwave FM discriminator that operates on the combined principles of an active and a passive microwave discriminator. This discriminator implemented from passive waveguide components and a Gunn oscillator is found to have a bandwidth equal to the lockband of the Gunn oscillator and frequency sensitivity greater than that of an active discriminator. The overall figure of merit of this discriminator is greater than that of a passive and an active microwave discriminator.
Microwave Sensing of Moisture Content and Bulk Density in Flowing Grain and Seed (2016)

<abstract> <b><sc>Abstract.</sc></b> Current techniques for rapid moisture measurement of grain and seed through sensing the dielectric properties in the 1 to 200 MHz frequency range require correction for density fluctuations and therefore are not suitable for reliable measurements on flowing grain. Density-independent moisture sensing in grain and seed is possible at microwave frequencies and has been successfully demonstrated on static samples. Bulk density of flowing grain can also be sensed simultaneously with moisture content. Although the theoretical basis for density-independent grain moisture measurement is expected to be useful for flowing materials, successful use has not previously been demonstrated. A laboratory flowing grain system was built for tests of microwave moisture measurement that were conducted on shelled field corn, wheat, and soybeans. Appropriate software was written to control a microwave network analyzer for the necessary attenuation and phase measurements, and tests were run on flowing grain and seed materials at high and low moisture levels and at low, medium, and high flow rates. Results confirmed that moisture readings obtained on static and flowing grain and seed agreed well, demonstrating the usefulness of the microwave density-independent technique for monitoring moisture content of flowing grain and seed. Bulk density determinations of static and flowing grain and seed also agreed well, indicating the usefulness of the technique for monitoring bulk density when desired.
Protein Nanocapsule Based Protein Carriers for Industrial and Medical Applications (2015)

Proteins play the most dynamic and diverse roles among all the biomacromolecules in living organisms. With the fast development in biotechnology, protein gains more and more interests for a wide range of applications, such as biochemical synthesis, sensing, environmental protection and medical applications. However, the vulnerable nature of proteins has hindered their boarder applications. Developing vectors and stabilizers that help to more effectively deliver protein therapeutics or stabilize proteins has been an essential theme of the field.In this dissertation, novel strategies have been developed for protein delivery by a method of in-situ free-radical polymerization or by a self-assembling/ crosslinking approach. Protein nanocapsules made from the in-situ polymerization method were also used building blocks to synthesize protein composites with dramatically enhanced stability. This dissertation research consist with four topics outlined below: 1.\tOrganophosphorus hydrolase (OPH) nanocapsules were synthesized by in-situ free-radical polymerization with enhanced activity and stability. These nanocapsules are highly potent for decontamination, as well as in vivo detoxification of organophosphorus as prophylactics or antidotes. 2.\tProtein nanocapsules made by the in-situ polymerization technique were used as building blocks to synthesize protein-silica composites through a sol-gel process. The microenvironment around the proteins was engineered through judicious choices of the polymer monomers and the silica precursors, enabling the synthesis robust enzyme composites with high activity for various industry applications.3.\tProtein nanocapsules were synthesized by assembling the proteins with self-crosslinking cell penetrating polymer (SCP). Self-crosslinking by disulfide-bond formation within the SCP leads to the formation of robust protein nanocapsules with highly retained activity. These nanocapsules were able to be effectively internalized by cells without significant cytotoxicity, and the protein cargo could be effectively released upon exposure to glutathione that break down the disulfide bonds.4.\tProtein nanocapsules with zwitterionic shells were synthesized by a self-assembling approach. The zwitterionic shells protected the nanocapsules from being uptake by macrophages, while such shells could be detached once exposing to a low pH environment. This approach provides a suitable platform towards protein therapeutics with prolonged circulation time with ability of being delivered into the cells.Overall, this dissertation work provides novel strategies toward better protein-delivery vectors, as well as composites with better protein stability and activity, for a broad range of applications.
Clinical observation of the application of enhanced recovery after surgery in treating hilarcholangiocarcinoma (2020)

Objective
To investigate the feasibility and safety of the application of Enhanced Recovery After Surgery (ERAS) in the perioperative treatment of hilar cholangiocarcinoma (HCCA).


Methods
A retrospective study was conducted in 48 patients with HCCA and underwent surgical treatment from January 2015 to January 2018. Among them, there were 25 cases underwent ERAS perioperative management (ERAS group), while 23 cases underwent traditionally perioperative management (traditional group). Statistical analysis were performed by using spss 19.0 software. Measurement data, such as intraoperative and postoperative indicators, postoperative pain scores and patient satisfaction were expressed as (±s), and were examined by using independent t test. Count data such as complication rates were examined by chi square test. A P value <0.05 was considered as statistically significant difference.


Results
There was no significant difference in terms of TBIL, ALT, AST and ALB between two groups before operation. However on the 7th day after operation, the TBIL, ALT, AST were significantly lower and ALB was significantly higher in ERAS group than those in traditional group respectively (P<0.05). The first anal exsufflation time, postoperative hospital stay, and medical costs were significantly lower in ERAS group than those in traditional group respectively (P<0.05). There were 2 cases(8%) of postoperative complications occurred in ERAS group, which were significantly lower than 9 cases (39.1%) in traditional group.


Conclusions
It is feasible, safe and effective that perioperative ERAS management in treating HCCA, which is helpful to accelerate the postoperative recovery and could improve the prognosis of patients.


Key words: 
Bile duct neoplasms; Rehabilitation; Perioperative; Comparative effectiveness research
Training recurrent networks using the extended Kalman filter (2003)

The author describes some relationships between the extended Kalman filter (EKF) as applied to recurrent net learning and some simpler techniques that are more widely used. In particular, making certain simplifications to the EKF gives rise to an algorithm essentially identical to the real-time recurrent learning (RTRL) algorithm. Since the EKF involves adjusting unit activity in the network, it also provides a principled generalization of the teacher forcing technique. Preliminary simulation experiments on simple finite-state Boolean tasks indicated that the EKF can provide substantial speed-up in number of time steps required for training on such problems when compared with simpler online gradient algorithms. The computational requirements of the EKF are steep, but scale with network size at the same rate as RTRL.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
View-independent scene acquisition for tele-presence (2002)

Tele-immersion is a new medium that enables a user to share a virtual space with remote participants. The user is immersed in a rendered 3D-world that is transmitted from a remote site. To acquire this 3D description we apply bi- and trinocular stereo techniques. The challenge is to compute dense stereo range data at high frame rates, since participants cannot easily communicate if the processing cycle or network latencies are long. Moreover, new views of the received 3D-world must be as accurate as possible. We address both issues of speed and accuracy and we propose a method for combining motion and stereo in order to increase speed and robustness.
DYEING OF SULFONATION AND CROSSLINKED COTTON FABRIC (2009)

Abstract Cotton fabrics were modified by different methods such as oxidation, sulfonation and crosslinking processes. The modified and unmodified fabrics were subjected to weight measurements, water absorbency and strength tests. In SEM analysis, modified fabrics showed improved woven pattern with less protruding fibres in x 75 magnification and swollen smooth rod like appearances in x 1500 magnification than in unmodified fabrics. Modified fabrics were dyed with Reactive Red 120 and Direct Blue 86 under alkaline condition with low salt content. The modified fabrics showed improved dye uptake than unmodified fabric. Crosslinking modification was found to be very effective than sulfonation modification. Dye uptake and wet fastness properties were improved for modified fabrics. For a 0.5% dye concentration study, the dye uptake obtained for modifications is ranked as UM < 1W < 2W < 4W < 3W in reactive dyeing and UM < 1W < 4W <2W <3W in direct dyeing.
A solid‐state NMR study of the fast and slow dynamics of collagen fibrils at varying hydration levels (2004)

We report solid-state NMR investigations of the effect of temperature and hydration on the molecular mobility of collagen isolated from bovine achilles tendon. (13)C cross-polarization magic angle spinning (MAS) experiments were performed on samples at natural abundance, using NMR methods that detect motionally averaged dipolar interactions and chemical shift anisotropies and also slow reorientational processes. Fast motions with correlation times much shorter than 40 micro s scale dipolar couplings and chemical shift anisotropies of the carbon sites in collagen. These motionally averaged anisotropic interactions provide a measure of the amplitudes of the segmental motions expressed by a molecular order parameter. The data reveal that increasing hydration has a much stronger effect on the amplitude of the molecular processes than increasing temperature. In particular, the Cgamma carbons of the hydroxyproline residues exhibit a strong dependence of the amplitude of motion on the hydration level. This could be correlated with the effect of hydration on the hydrogen bonding structure in collagen, for which this residue is known to play a crucial role. The applicability of 1D MAS exchange experiments to investigate motions on the millisecond time-scale is discussed and first results are presented. Slow motions with correlation times of the order of milliseconds have also been detected for hydrated collagen.
An approach to harmonic current-free AC/DC power conversion for large industrial loads: the integration of a series active filter with a double-series diode rectifier (1997)

This paper proposes a new harmonic current-free ac/dc power conversion system characterized by the integration of a small-rated series active filter with a large-rated doubleseries diode rectifier.The dc terminals of the active filter are directly connected in parallel with those of the diode rectifier, thereby forming a common dc bus.The active filter enables the diode rectifier to draw three-phase sinusoidal currents from the utility.In addition, it can provide the supplementary value-added function of regulating the common dc-bus voltage to a limited extent of 65%, slightly increasing the rms voltage rating, but not increasing the peak voltage rating.Experimental results obtained from a 5-kW laboratory system verify the practical viability and cost effectiveness of the proposed system. Index Terms-Diode
Methyl-binding domain protein-based DNA isolation from human blood serum combines DNA analyses and serum-autoantibody testing (2011)

MBD affinity purification allows DNA isolations under native conditions retaining the protein function, thus for example enabling combined analyses of DNA methylation and autoantigene-profiles from the same serum sample and thereby improving minimal invasive diagnostics.
Loricrin Expression in Cultured Human Keratinocytes Is Controlled by a Complex Interplay between Transcription Factors of the Sp1, CREB, AP1, and AP2 Families (2002)

The major protein component of the cornified cell envelope barrier structure of the epidermis is loricrin, and it is expressed late during terminal differentiation in epidermal keratinocytes. We have previously shown that an AP1 site located in the proximal promoter region (position -55) is essential for human loricrin promoter activity (Rossi, A., Jang, S-I., Ceci, R., Steinert, P. M., and Markova, N. G. (1998) J. Invest. Dermatol. 110, 34-40). In this study we show that its regulation requires complex cooperative and competitive interactions between multiple transcription factors in keratinocytes located in different compartments of the epidermis. We show that as few as 154 base pairs of 5'-upstream sequences from the cap site can direct the keratinocyte-specific expression in cultured keratinocytes. Mutation and DNA-protein analyses show that Sp1, c-Jun, an unidentified regulator, and the co-activator p300/CREB-binding protein up-regulate whereas Sp3, CREB-1/CREMalpha/ATF-1, Jun B, and an AP2-like protein (termed the keratinocyte-specific repressor-1 (KSR-1)) suppress loricrin promoter activity. We show that CREB protein can compete with c-Jun for the AP1 site and repress loricrin promoter activity. We show here that the protein kinase A pathway can activate loricrin expression by manipulation of the Sp1, Sp3, and KSR-1 levels in the nucleus. Thus, in undifferentiated cells, loricrin expression is suppressed by Jun B, Sp3, and KSR-1 proteins. But in advanced differentiated cells, levels of Sp3, KSR-1, and CREB proteins are lower; the unidentified regulator protein can bind; Sp1 and c-Jun are increased; and then p300/CBP is recruited. Together, these events allow loricrin transcription to proceed. Indeed, the synergistic effects of the Sp1, c-Jun, and p300 factors indicate that p300/CBP might act as bridge to form an active transcription complex.
Expression of Neutralizing Recombinant Human Antibodies Against Varicella Zoster Virus for Use as a Potential Prophylactic (2000)

Chickenpox is a highly infectious disease that can be life-threatening to certain groups such as the newborn of nonimmune mothers and immunocompromised patients. At present, prophylactic treatment of individuals at risk involves the use of a polyclonal antibody preparation derived from the pooled sera of hyperimmune donors. While this product is effective, there are problems associated with maintaining supply, which depends on the availability of donors, and the variation of potency between batches. An effective human monoclonal preparation would be of value by providing a well-characterized and standardized preparation available on demand. In this study recombinant human anti-varicella zoster virus (VZV) monoclonals were generated from the mRNA of unstable anti-VZV secreting heterohybridoma cell lines, and characterized according to their molecular weight, isoelectric point, glycosylation, binding to C1q, and efficacy at neutralizing VZV in vitro. In one antibody (AEVZ 5.3) the VH region was grafted from the IgG1 parent antibody onto an IgG3 backbone to determine the effect of isotype on neutralization in vitro. Antibodies were expressed from NSO cells at concentrations of 3-24 microg/mL and contained the expected heavy and light chain fragments and N-linked glycan structures. Both AEVZ 5.1 and AVEZ 4 antibodies were IgG1 and recognized the viral coat protein glycoprotein E; both showed complement-independent and complement-enhanced neutralization. Changing the isotype of AEVZ 5.1 from IgG1 to IgG3 (AEVZ 5.3) further enhanced VZV neutralization in the presence of complement, but reduced its neutralization capacity in the absence of complement. Complement enhancement was consistent with our findings that the IgG3 form could bind more molecules of C1q. The results demonstrate the successful use of recombinant methods to generate stable, functional monoclonal antibodies. Modifications of the original antibodies were made with the aim of improving functionality. The resulting cell lines could be used for large-scale production of well-characterized antibodies for therapeutic use.
Knowledge-based Dynamic Packaging Model (2006)

The rapid growth of the Internet and the continual adoption of innovative technology have led to serious changes in the travel industry during the last decade. Due to the constantly changing business environment, one of the latest concepts of the tourist industry is "dynamic packaging". While dynamic packaging has been widely accepted by customers, the strategic impacts enabled by dynamic packaging technologies are still uncertain. This paper provides a study of an extension of the traditional packaging architecture and aims to present a new and extended model, called the knowledge-based dynamic packaging model
Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosis (2016)

Progressive macular hypomelanosis (PMH) is a common skin disorder that causes hypopigmentation in a variety of skin types. Although the underlying aetiology of this condition is unclear, there is circumstantial evidence that links the skin bacterium Propionibacterium acnes to the condition. We now describe the first detailed population genetic analysis of P. acnes isolates recovered from paired lesional and non-lesional skin of PMH patients. Our results demonstrate a strong statistical association between strains from the type III phylogenetic lineage and PMH lesions (P = 0.0019), but not those representing other phylogroups, including those associated with acne (type IA1). We also demonstrate, based on in silico 16S rDNA analysis, that PMH isolates previously recovered from patients in Europe are also consistent with the type III lineage. Using comparative genome analysis, we identified multiple genomic regions that are specific for, or absent from, type III strains compared to other phylogroups. In the former case, these include open reading frames with putative functions in metabolism, transport and transcriptional regulation, as well as predicted proteins of unknown function. Further study of these genomic elements, along with transcriptional and functional analyses, may help to explain why type III strains are associated with PMH.