gebhart/patrepeval huggingface dataset:
Mixed Scale Motion Recovery Using Guidable Cameras (2000)

Captured human motion is widely used by the medical, surveillance, and entertainment industries. In these fields, many interesting motions occur at mixed scales. Subtle localized motion often occurs together with long range movements. One of the chief challenges in recovering these motions is to obtain high resolution imagery suitable for resolving small details, while simultaneously increasing the working volume in which recovery is possible. This paper proposes an architecture for mixed scale motion recovery. Robust coverage of a large working volume is provided by a wide area tracking system. This system localizes interesting motions, and guides a separate foveated system of pan-tilt cameras to observe the detailed motion at high resolution. We demonstrate two applications, foveated structured light scanning and the capture of muscle deformation while walking. Both applications allow recovery of subtle detailed motion that would not be possible using existing single scale systems. 1.
Elemental Reactions in Copolymerization of α-Olefins by Bis(cyclopentadienyl) Zirconocene and Hafnocene: Effects of the Metal as a Function of the Monomer and the Chain End (2011)

The effect of the metal on elementary chain propagation and termination reactions in hafnocene- and zirconocene-catalyzed olefin copolymerization processes has been systematically studied by quantum chemical methods. Two consecutive monomer insertions, parallel with the competing chain termination reactions, were studied for copolymerization of ethene with propene, 1-butene, and 1-hexene. For the purpose of a comparative study, analogous species along the reaction pathway were studied for each metallocene/monomer combination. Effects due to incorporation of a comonomer were analyzed as a function of both the central metal and the comonomer size. In accordance with the general experimental observations of zirconocenes producing lower molecular weight polymer than the hafnocenes, differences in activation energies for chain propagation and termination are smaller for the zirconocene. For the zirconocene, the activation energy is particularly low for β-hydrogen elimination after secondary comonomer insertion.
Role of hydrogen bonding in the formation of glasses by small molecules: a triazine case study (2009)

Diaminotriazine derivatives with 3,5-dimethylphenyl groups have been shown to be capable of readily forming extremely stable glassy phases under ambient conditions, and self-assembly through hydrogen bonding has been thought to be a key element in this process. Herein, we probed the role played by hydrogen bonding in glass formation in this family of compounds by studying the crystal structures of both molecular glasses and closely similar compounds that crystallize under ambient conditions. We also compared a molecular glass in the crystalline and amorphous states by FTIR spectroscopy to monitor changes at the molecular level as the material underwent glass transition. We have shown that hydrogen bonding favors glass formation through the formation of aggregates that pack poorly, and breaking of hydrogen bonds plays a role in the physical changes associated with glass transition.
Jet Vapor Deposition: A New, Low Cost Metallization Process (1997)

We describe the basics of the Jet Vapor Deposition (JVD ) process and its current and potential applications in microelectronics and packaging. JVD is distinct from conventional PVD and CVD processes in that it operates in low vacuum and uses sonic gas jets to transport depositing materials in atomic or molecular form. JVD's operating conditions are ideal for generating and sustaining high density plasmas which provide a wide range of processing capabilities such as ion bombardment and reactive deposition. The net result is a low cost yet extremely powerful and versatile deposition technology. Comparison will be made to conventional thin film technologies.
"Retroposon" insertion into the cellular oncogene c-myc in canine transmissible venereal tumor. (1985)

We examined by Southern blotting the state of the cellular oncogene c-myc in the dog transmissible venereal tumor. The tumor DNA contains a 16.8-kilobase pair (kbp) rearranged c-myc fragment in addition to the normal 15-kbp and 7.5-kbp fragments. We compared the structure of the cloned rearranged c-myc (re-myc) with that of a cloned normal c-myc and found that the rearrangement was due to the insertion of a 1.8-kbp DNA upstream to the first exon of c-myc. The inserted DNA is flanked by 10-base-pair direct repeats and contains a dA-rich tail, suggesting its origin from mRNA. Partial sequence of the inserted element showed 62% homology with the primate interdispersed Kpn I repetitive element. These results provide an example for the behavior of repetitive DNA sequences like the Kpn I family, as movable elements that can transpose nearby to oncogenes or other structural genes and perhaps affect their activity.
Silicate Cluster Fluids (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSilicate Cluster FluidsRobert N. Scott, Karl O. Knollmueller, Frank J. Milnes, Thomas A. Knowles, and David F. GavinCite this: Ind. Eng. Chem. Prod. Res. Dev. 1980, 19, 1, 6–11Publication Date (Print):March 1, 1980Publication History Published online1 May 2002Published inissue 1 March 1980https://pubs.acs.org/doi/10.1021/i360073a003https://doi.org/10.1021/i360073a003research-articleACS PublicationsRequest reuse permissionsArticle Views52Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
The T9000 transputer (2003)

Some of the issues arising in the design of the T9000 transputer, which integrates a complete computer in a single VLSI chip of over two million transistors, are discussed. High performance has been achieved by extensive use of caching and a novel processor implementation. The processor uses a fat pipeline and dispatches several dependent instructions into the pipeline each cycle. The resulting processor is able to saturate a 25-MFLOP floating-point unit. The processor is supported by a communications system that supports communications at high speed and low latency.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Lysosomal Glycosidases in Mouse Peritoneal Macrophages Stimulated In Vitro With Soluble and Insoluble Glycans (1984)

Mouse peritoneal macrophages stimulated with insoluble glycans in vitro release high amounts of acid hydrolases, N-acetyl-beta-D-glucosaminidase, beta-D-glucuronidase, and beta-D-galactosidase. The most potent of the stimulatory glycans is a beta-1,3-D-glucan isolated from yeast cell walls. Up to 50% of total enzyme activity was found in the medium after stimulation with this glycan for three days. Agarose, another insoluble glycan containing an alternating sequence of the disaccharide beta-1,3-D-galactose-alpha-1,4-3,6-anhydro-L-galactose units was less potent. The soluble beta-1,3-D-glucan laminaran, which also contains small amounts of mannitol, was not able to induce release of acid glycosidases from macrophages. The release was independent of serum since macrophages cultured under serum-free conditions showed nearly the same pattern of enzyme activities, both in the cells and media. There was no increased release of the acid hydrolase alpha-D-mannosidase after stimulation with the insoluble beta-1,3-D-glucan for three days. The release of the lysosomal glycosidases was not due to cell death, since only small amounts of the cytoplasmic enzyme lactate dehydrogenase were found in the culture media. Insoluble polystyrene latex particles were not able to stimulate mouse macrophages to release lysosomal glycosidases. Tritiated glycans (amylose, dextran, laminaran, the insoluble beta-1,3-D-glucan, and agarose) and the p-nitrophenyl-glycopyranoside derivatives were used as substrates to investigate whether the macrophages contained or released glucanases capable of degrading alpha-1,4-D-glucans, alpha-1-6-D-glucans, beta-1,3-D-glucans, and agarose respectively. We conclude that the glycans were not degraded in macrophage cultures during the time period tested nor were the enzymes induced in macrophages by the glycans during in vitro culture for seven days.
Signal requirement for induction of MHC-unrestricted antitumor cytotoxicity of human T cell CD4+/CD8+ subpopulations. (1994)

The role of cosignalling in the generation of MHC-unrestricted cytotoxicity of T cells was studied with CD4+ and CD8+ sub-populations highly purified (> 98%) by immunomagnetic cell sorting using OKT4 mab, Dynal anti-CD4 mab, OKT8 mab, Dynal anti-CD8 mab, and OKT3 mab. Cytotoxicity was determined in 4 h cytotoxicity assays against K562 tumor cells known to lack expression of MHC class 1 and class 2 antigens, thus avoiding interference with anti-CD4- or anti-CD8-mediated signalling. Signal transfer was induced via CD4, CD8, CD3, IL-2 receptor and RG receptor specifically interacting with a plant rhamnogalacturonan (RG). In CD8+ cells, the first signal delivered by the sorting mab (immobilized OKT8 or Dynal anti-CD8 or OKT3) only induced low MHC-unrestricted cytotoxicity but committed the cells to develop largely enhanced cytolytic potential upon stimulation with a second (IL-2 or RG) or third (OKT3, IL-2, RG) signal. The highest cytolytic potential was achieved by cumulative signalling via CD8, CD3, IL-2 receptor and RG receptor. The generation of MHC-unrestricted cytotoxicity of CD8+ cells correlated with increased effector cell/target cell conjugate formation. In CD4+ cells, OKT4 as sorting mab induced very low cytolytic potential, and a moderate committment to IL-2 signals but a stronger one to RG signals, yielding further cytotoxicity enhancement. The highest cytolytic potential was obtained by cumulative signalling via CD4, IL-2 receptor and RG receptor. Dynal anti-CD4 mab was inefficient and OKT3, as sorting mab of CD4+ cells from CD8-depleted PNAC, appeared to block subsequent OKT4-induced generation of MHC-unrestricted cytotoxicity by delivering a negative signal. Immobilized OKT3 as second signal present in cultures of OKT4-sorted CD4+ cells was inefficient. Surprisingly, soluble OKT3 together with IL-2 delivered a positive signal in cultures of OKT4-sorted CD4+ cells.
Recent developments in vertical hoisting systems (1994)

This paper reviews some of the more interesting developments which have occurred over the past decade in the design and application of mine hoisting systems. Improvements in basic technology relating to design of electrical and mechanical components of the winder as well as major changes in the way these systems are operated and maintained have all contributed to the enhanced safety and productivity offered by the latest generation of mine winders.
Subsurface Super-resolution Imaging of Unstained Polymer Nanostructures (2016)

Optical imaging has offered unique advantages in material researches, such as spectroscopy and lifetime measurements of deeply embedded materials, which cannot be matched using electron or scanning-probe microscopy. Unfortunately, conventional optical imaging cannot provide the spatial resolutions necessary for many nanoscopic studies. Despite recent rapid progress, super-resolution optical imaging has yet to be widely applied to non-biological materials. Herein we describe a method for nanoscopic optical imaging of buried polymer nanostructures without the need for extrinsic staining. We observed intrinsic stochastic fluorescence emission or blinking from unstained polymers and performed spatial-temporal spectral analysis to investigate its origin. We further applied photon localization super-resolution imaging reconstruction to the detected stochastic blinking, and achieved a spatial resolution of at least 100 nm, which corresponds to a six-fold increase over the optical diffraction limit. This work demonstrates the potential for studying the static heterogeneities of intrinsic polymer molecular-specific properties at sub-diffraction-limited optical resolutions.
A True Time Delay 16-Element 4-Beam Digital Beamformer (2018)

Large phased arrays are limited by inaccurate beam steering (squinting) and by distortion in analog-to-digital conversion. This paper introduces the first integrated digital true time delay beamforming receiver. The true time delay eliminates squinting, making it ideal for large-array wide-bandwidth applications. The beamformer incorporates a new current-steering DAC architecture providing a constant output impedance to improve ADC linearity. This significantly reduces distortion, leading to an SFDR improvement of 13.7 dB from the array. The prototype achieves an EVM better than -37 dB for 5 MBd 256-QAM and 512-QAM. The measured beam patterns are near-ideal for both conventional and adaptive beamforming. The prototype digital beamformer supports 16 antennas and 4 independent beams. It occupies only 0.29 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and consumes 453 mW.
Fractionated Irradiation Combined with Carbogen Breathing and Nicotinamide of Two Human Glioblastomas Grafted in Nude Mice (2001)

This study addressed the potential radiosensitizing effect of nicotinamide and/or carbogen on human glioblastoma xenografts in nude mice. U-87MG and LN-Z308 tumors were irradiated with either 20 fractions over 12 days or 5 fractions over 5 days in air-breathing mice, mice injected with nicotinamide, mice breathing carbogen, or mice receiving nicotinamide plus carbogen. The responses to treatment were assessed using local control and moist desquamation. In U-87MG tumors, the enhancement ratios (ERs) at the radiation dose required to produce local tumor control in 50% of the treated mice (TCD(50)) with nicotinamide and/or carbogen ranged from 1.13 to 1.24 for irradiation in 20 fractions over 12 days. In LN-Z308 tumors, the ERs at the TCD(50) with nicotinamide and/or carbogen ranged from 1.22 to 1.40 for irradiation in 5 fractions over 5 days and from 1.11 to 1.30 in 20 fractions over 12 days, respectively. Skin injury was slightly enhanced, with ERs ranged from 1.06 to 1.15 when radiation was combined with carbogen and/or nicotinamide. Thus carbogen and nicotinamide can slightly improve the radiation response of human glioblastoma xenografts.
Balancing Robots using Vestibular Dynamic Inclinometer (2010)

The balance of robots has traditionally been ac- complished using Inertial Measurement Units (IMUs) which use linear accelerations and gyroscope data to track the orientation of the vertical direction in inertial space. A novel approach, motivated by the human vestibular system in the human ear, is presented in this paper. It discusses the use of two linear accelerometers per axis to obtain linear acceleration, angular velocity, and inclination of a body relative to the directio n of gravity. The otoliths are modeled as simple damped linear accelerometers, yielding a static inclination reading when the values are averaged together, and an angular velocity magnitude and angular acceleration reading when the differences are taken between corresponding left and right sensors. The semicircular canals are modeled as fluid integrators of angular accelerat ion yielding angular velocity as cupular deflection. Kinematic anal- ysis shows that combining these vestibular readings properly yields in the general case, irrespective of gravity or senso r array location, a fully effective dynamic inclinometer, which continually senses the direction of stability, and is not su bject to drift or integration errors. Further, kinematic analysis shows that effective gravity can be read as a sensed vestibular value, and restorative torque can be applied in proportion to this sensed value, making the robot more robust to altered or rapidly changing instantaneous gravity conditions. The design is powerful as it outputs dynamic inclination of a body with- out requiring significant computational burden, irrespect ive of gravity or sensor array location, and is not subject to drift or integration errors. Vestibular Dynamic Inclinometer (VDI), as presented here, is robust to altered or rapidly changing gravity. Finally, for all these reasons the cost of making the VDI is greatly reduced relative to IMUs. The calculations discussed in the paper are for planar case and can be extended to other axes.
Light chain amyloidosis 2012: a new era (2013)

AL amyloidosis patients with multi-organ and particularly cardiac involvement have historically been considered to have a bad prognosis. The introduction of autologous stem cell transplantation was associated with unacceptable toxicity in high-risk patients, but responding patients have prolonged overall survival. Toxicities can be decreased by careful patient selection, but this reduces the applicability of this treatment modality to a limited number of patients. Efforts are therefore needed to design novel more effective regimens, with the use of new medications, such as thalidomide, lenalidomide and bortezomib, next generation immunomodulatory drugs and proteasome inhibitors. Their combination with dexamethasone and alkylating agents show promising results, allowing a high percentage of remission and subsequent event-free and overall survival, even in a significant proportion of high risk, poor prognosis populations. This review includes the state-of-the-art treatment for AL amyloidosis patients as of 2012, in light of the progress in management of this disease during recent years.
Intratumoral immunotherapy with the TLR7/8 agonist 3M-052 (2013)

Meeting abstracts TLR agonists have demonstrated anti-tumor activity in both animals and humans. Clinically, successful anti-tumor activity with TLR agonists was most often observed when the molecules were applied locally to dermatological cancers. This mode of administration was also associated
Concentration and detection of hepatitis A virus and rotavirus from shellfish by hybridization tests (1991)

A modified polyethylene glycol precipitation method for concentration of virus followed by a new method to recover nucleic acid was used to detect hepatitis A virus (HAV) and rotavirus (SA11) in shellfish (oysters and hard-shell clams) by hybridization tests. Infectious virus, seeded into relatively large quantities of shellfish, was recovered consistently, with greater than 90% efficiency as measured by either in situ hybridization (HAV) or plaque assay (rotavirus SA11). Viral nucleic acid for dot blot hybridization assays was extracted and purified from virus-containing polyethylene glycol concentrates. Separation of shellfish polysaccharides from nucleic acid was necessary before viral RNA could be detected by dot blot hybridization. Removal of shellfish polysaccharides was accomplished by using the cationic detergent cetyltrimethylammonium bromide (CTAB). Use of CTAB reduced background interference with hybridization signals, which resulted in increased hybridization test sensitivity. After polysaccharide removal, dot blot hybridization assays could detect approximately 10(6) physical particles (corresponding to approximately 10(3) infectious particles) of HAV and 10(4) PFU of SA11 rotavirus present in 20-g samples of oyster and clam meats. These studies show continuing promise for the development of uniform methods to directly detect human viral pathogens in different types of shellfish. However, practical applications of such methods to detect noncultivatable human viral pathogens of public health interest will require additional improvements in test sensitivity.
Synthesis of agarose‐<i>graft</i>‐hyaluronan copolymer and its potential application as a peptide carrier (2010)

Abstract A novel water‐soluble copolymer, agarose‐ graft ‐hyaluronan (Ag‐ g ‐HA), was synthesized as a peptide carrier, and selected properties were evaluated. In brief, agarose was degraded by hydrogen peroxide to achieve agarose with a low gelling temperature and a low molecular weight, activated by epichlorohydrin, and grafted with hyaluronic acid. The IR spectrum results of the Ag‐ g ‐HA copolymer showed that there were specific absorption peaks of hyaluronan at 1609 cm −1 (CO), which proved that hyaluronan was successfully grafted onto the agarose chain. The elemental analysis results showed that the nitrogen content of Ag‐ g ‐HA was 2.57%. The grafting ratio of epoxy groups was deduced to be 66.41% according to the N content of the copolymer. The ζ potential analysis results disclosed that Ag‐ g ‐HA became negative with increasing pH above 3. Ag‐ g ‐HA/insulin (INS) polyelectrolyte complexes were formed via electrostatic interaction at pH 3–5.4. The results of atomic force microscopy and ζ potential analyses demonstrated that Ag‐ g ‐HA and INS could spontaneously form microparticles with average diameters of 2–10 μm. The result of an INS‐releasing experiment in vitro disclosed that these particles had a significant burst release effect during the initial 30 min of release at pH 1.2 or 7.4, but the release behavior was ideal in the environment of pH 6.8. The release data could be described by the Weibull equation. These results demonstrate that the Ag‐ g ‐HA copolymer possessed potential as a peptide carrier. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Iron and oxygen regulation of <i>Escherichia coli</i> MnSOD expression: competition between the global regulators Fur and ArcA for binding to DNA (1993)

Manganese superoxide dismutase (the sodA gene product) in Escherichia coli, is negatively regulated by two global regulators, ArcA (aerobic respiration control) and Fur (ferric uptake regulation), coupling its expression to aerobic metabolism and the intracellular iron pool. Footprinting analyses were carried out on the sodA promoter region with purified Fur protein and with ArcA protein overproduced in crude extracts. ArcA is able to bind in vitro in the absence of the in vivo triggering signal. The binding occurs in one step and study of contacts within the operator sequence reveals binding on one side of the double helix. The DNA protection extends to a much larger region (about 65 bp) than would be expected for a 27 kDa protein, suggesting polymerization. Both Fur and ArcA footprints encompass the -35 and -10 promoter region and there is considerable overlap of their binding sequences, in agreement with in vivo results suggesting that either regulator alone can block sodA transcription. Furthermore, competition experiments show that Fur and ArcA binding to the sodA promoter are mutually exclusive and that ArcA can easily displace Fur, but not vice versa. The biological significance of this in vitro behaviour is discussed.