gebhart/patrepeval huggingface dataset:
Quantitative studies of single-cell properties in monkey striate cortex. II. Orientation specificity and ocular dominance (1976)

1. Quantitative analyses of orientation specificity and ocular dominance were carried out in striate cortex of the rhesus monkey. 2. Sharpness of orientation selectivity was greater for simple (S type) than for complex (CX type) cells. CX-type cells became more broadly tuned in the deeper cortical layers: S-type cells were equally well tuned throughout the cortex. 3. Sharpness of orientation selectivity for S-type cells was similar at all retinal eccentricities studied (0 degrees - 20 degrees from the fovea):in CX-type cells orientation selectivity decreased slightly with increasing eccentricity. 4. The orientation tuning of binocular cells was similar when mapped separately through each eye. 5. Orientation selectivity and direction selectivity are independent of each other, suggesting that separate neural mechanisms give rise to them. 6. More CX-type cells can be binocularly activated than S-type cells (88% versus 49%). The ocular dominance of S-type cells is similar in all cortical layers: for CX-type cells there is an increase in the number of cells in ocular-dominance category 4 in layers 5 and 6.
Molybdenum-rhenium superconducting suspended nanostructures (2014)

Suspended superconducting nanostructures of MoRe 50%/50% by weight are fabricated employing commonly used fabrication steps in micro- and nano-meter scale devices followed by wet-etching with Hydro-fluoric acid of a SiO2 sacrificial layer. Suspended superconducting channels as narrow as 50 nm and length 3 μm have a critical temperature of ≈6.5 K, which can increase by 0.5 K upon annealing at 400 °C. A detailed study of the dependence of the superconducting critical current and critical temperature upon annealing and in devices with different channel widths reveals that desorption of contaminants is responsible for the improved superconducting properties. These findings pave the way for the development of superconducting electromechanical devices using standard fabrication techniques.
Expression of the Gene for Sucrose Synthase during Growth of Mung Bean Seedlings (1992)

Journal Article Expression of the Gene for Sucrose Synthase during Growth of Mung Bean Seedlings Get access Masao Arai, Masao Arai 1Research Institute for Biochemical Regulation, School of Agricultural Sciences, Nagoya UniversityChikusa, Nagoya, 464-01 Japan2Division of Biological Regulation, National Institute for Basic BiologyOkazaki, 444 Japan Search for other works by this author on: Oxford Academic Google Scholar Hitoshi Mori, Hitoshi Mori 2Division of Biological Regulation, National Institute for Basic BiologyOkazaki, 444 Japan Search for other works by this author on: Oxford Academic Google Scholar Hidemasa Imaseki Hidemasa Imaseki 3 1Research Institute for Biochemical Regulation, School of Agricultural Sciences, Nagoya UniversityChikusa, Nagoya, 464-01 Japan2Division of Biological Regulation, National Institute for Basic BiologyOkazaki, 444 Japan 3To whom requests for reprints should be addressed at Nagoya University Search for other works by this author on: Oxford Academic Google Scholar Plant and Cell Physiology, Volume 33, Issue 4, June 1992, Pages 503–506, https://doi.org/10.1093/oxfordjournals.pcp.a078282 Published: 01 June 1992 Article history Received: 21 January 1992 Accepted: 25 March 1992 Published: 01 June 1992
Process options for converting renewable feedstocks to bioproducts (2007)

This paper discusses the relative advantages of different process options to convert renewable feedstocks (carbohydrates, vegetable oils, terpenes and lignocellulosic materials) into valuable chemicals and polymers. Three process options are considered: (1) via degraded molecules, (2) via platform molecules, (3) via one-pot processes. These routes can all be integrated in a biorefinery scheme which maximises the value derived from biomass. These process options are illustrated by selected examples underlining the green chemistry value of process options 2 and 3. Stress is laid on new value chains adapted to biomass composition and on the use of recyclable heterogeneous catalysts that lead to waste minimisation and decrease the processing cost of renewables.
Energy-spectral Compton scatter imaging. I. Theory and mathematics (1995)

A technique for tomographic imaging of electron density using the energy spectrum of Compton scattered gamma-rays is described. The energy-angle relationship for Compton scattering is utilized to determine the direction of scattered photons. A single-scattering "forward mapping" model is constructed to relate electron density to the detector response. The nonlinearity of the model, caused by accounting for pre- and post-scattering radiation attenuation, is dealt with by solving the "inverse mapping" iteratively. In order to assure convergence of the image reconstruction problem to a nonnegative and bounded solution, a variety of "regularization" algorithms are examined. The capabilities and limitations of these algorithms are demonstrated by reconstructing a number of images from Monte Carlo simulated measurements. Part II of this paper presents the experimental aspects of the technique.
Collaborative, Individualized Assessment (2000)

Collaborative, individualized assessment is an approach to psychological assessment in which the assessor and the client work together to develop productive understandings. Collaboration is a means of individualizing the assessment--its process, resulting suggestions, and written accounts. In this approach, life events are regarded as primary data. Test scores, categories, and related research are used as bridges into a particular life and as tools for then exploring that life. This article, an invited Master Lecture presented at the 1999 Society for Personality Assessment (SPA) meeting, presents examples of contextualizing, intervening, describing in life-world terms, and writing individualized reports with suggestions. Historical struggles to promote individualized assessment and current openness to its practices, especially within SPA, are mentioned. A hermeneutic approach to impression formation is described.
Autologous mesenchymal stem cell treatment increased T regulatory cells with no effect on disease activity in two systemic lupus erythematosus patients (2009)

Mesenchymal stem cells (MSCs) exert suppressive effects in several disease models including lupus prone mice. However, autologous MSC therapy has not been tested in human systemic lupus erythematosus (SLE). We evaluate the safety and efficacy of bone marrow (BM)-derived MSCs in two SLE patients; the suppressor effect of these cells in-vitro and the change in CD4+CD25+FoxP3+ T regulatory (Treg) cells in response to treatment. Two females (JQ and SA) of 19 and 25 years of age, fulfilling the 1997 American College of Rheumatology (ACR) criteria for SLE were infused with autologous BM-derived MSCs. Disease activity indexes and immunological parameters were assessed at baseline, 1, 2, 7 and 14 weeks. Peripheral blood lymphocyte (PBL) subsets and Treg cells were quantitated by flow cytometry, and MSCs tested for in-vitro suppression of activation and proliferation of normal PBLs. No adverse effects or change in disease activity indexes were noted during 14 weeks of follow-up, although circulating Treg cells increased markedly. Patient MSCs effectively suppressed in-vitro PBL function. However, JQ developed overt renal disease 4 months after infusion. MSC infusion was without adverse effects, but did not modify initial disease activity in spite of increasing CD4+CD25+FoxP3+ cell counts. One patient subsequently had a renal flare. We speculate that the suppressive effects of MSC-induced Treg cells might be dependent on a more inflammatory milieu, becoming clinically evident in patients with higher degrees of disease activity.
Shock and Vibration Testing of an AMB Supported Energy Storage Flywheel (2003)

Shock and vibration testing of an Active Magnetic Bearing (AMB) supported energy storage flywheel is presented. The flywheel is under development at the University of Texas-Center for Electromechanics (UT-CEM) for application in a transit bus. The flywheel is gimbal mounted to reduce the gyroscopic forces transmitted to the magnetic bearings during pitching and rolling motions of the bus. The system was placed on a hydraulic terrain simulator and driven through pitch, roll and shock motions equivalent to 150% of maximum expected bus frame values. Although the AMB control approach was originally developed specifically to ensure rotordynamic stability, relative rotor/housing motion was typically less than half of the backup bearing clearance under all tested conditions. Test results are presented and compared to analytical predictions for the 35000rpm nominal operating speed. The impact of the AMB control algorithm is discussed relative to the input forcing function.
Dorsale Luxation der PIP-Gelenke der Finger. Ergebnisse nach statischer und nach funktioneller Behandlung (2001)

In a follow-up examination of 30 patients who had sustained dorsal dislocations of the PIP joint, the results of two conservative therapy regimens, either immobilisation or early motion were investigated. In Group A, 15 patients were treated by closed reduction and immobilisation with a forearm cast for four weeks. Nine patients showed normal range of motion, whereas a limitation of extension of ten degrees and more was seen in six cases. All PIP joints were stable. Nine patients were satisfied. Three patients complained of a limitation of extension, two of a limitation of extension and pain and one of swelling. In Group B, 15 patients were treated by dorsal block splinting of the PIP joint following reposition. The finger was released in extension with daily active exercise of the PIP joint. Only two of 15 patients showed limitation of extension, whereas 13 cases showed normal range of motion. Instability of one collateral ligament was seen in two cases. Palmar instability did not occur. Eleven patients were satisfied. One patient complained of instability, pain and lack of extension, one of pain in combination with instability, one of pain and one of swelling of the joint.
Assignment Problems (2009)

This book provides a comprehensive treatment of assignment problems from their conceptual beginnings in the 1920s through present-day theoretical, algorithmic, and practical developments. The authors have organized the book into 10 self-contained chapters to make it easy for readers to use the specific chapters of interest to them without having to read the book linearly. Exercises in the form of numerical examples provide readers with a method of self-study or students with homework problems, and an associated web page ( www.siam.org/books/ot106/assignmentproblems.html) offers applets that readers can use to execute some of the basic algorithms as well as links to computer codes that are available online. \n \nTable of contents\nPreface; \nChapter 1: Introduction; \nChapter 2: Theoretical Foundations; \nChapter 3: Bipartite Matching Algorithms; \nChapter 4: Linear Sum Assignment Problem; \nChapter 5: Further Results on the Linear Sum Assignment Problem; \nChapter 6: Other Types of Linear Assignment Problems; \nChapter 7: Quadratic Assignment Problems: Formulations and Bounds; \nChapter 8: Quadratic Assignment Problems: Algorithms; \nChapter 9: Other Types of Quadratic Assignment Problems; \nChapter 10: Multi-index Assignment Problems; \nBibliography; \nAuthor Index; \nSubject Index\n\nFor more information please check \nhttp://www.ec-securehost.com/SIAM/OT106.html
Effects of UV-B radiation and water stress on soybean yield. (2009)

Soybean Dongnong47 was subjected to the experiments of the increasing UV-B radiation and water stress on soybean yield components during different growth periods. The results showed that 100-seed weight was greatly increased during early stage of pod filling in the treatment of weak UV-B radiation, seed number per plant as well as seed weight per plant and yield of soybean Dongnong47 were also increased, while the yield and yield components of soybean Dongnong47 during the blossom to mature period were negatively affected in the treatment of intensive UV-B radiation. 100-seed weight of Dongnong47 all increased in the double factor treatments of UV-B radiation and water stress; with the drought intensified, seed number per plant, seed weight per plant and yield of soybean Dongnong47 were decreased, but the changes of 100-seed weight were various, therefore the antagonistic action of UV-B radiation and water stress were related with their intensity.
Lack of specificity of endoglin expression for tumor blood vessels (2001)

A monoclonal antibody (MAb; A11) has been raised following mouse immunization with cultured human microvascular endothelial cells. The MAb showed a strong positivity within tumor vessels in glioblastoma and breast carcinoma samples, and the distribution was consistent with antigen association with vascular endothelial cells. A purification procedure of the antigen was developed starting from DG-RSV-LT-2, an immortalized human endothelial cell line. Molecular mass, N-terminal sequence of the purified antigen and localization on endothelial cell surface allowed identification with human endoglin (CD105). Flow cytometry analysis of a group of normal and transformed cell lines showed that, besides endothelial cells and myelocytic leukemia cells already shown to be positive, fetal fibroblasts, choriocarcinoma, fibrosarcoma and rhabdomyosarcoma cell lines were also positive for this antigen. Immunohistochemic analysis of several normal adult tissues revealed a more extensive presence of the antigen in normal vessels compared to that described with previously characterized antibodies. In fact, even though the staining was weaker than in tumor tissues, all tissues were found to be positive, at least in microvessels, except for normal breast. Moreover, in some tissues (glands and reproductive tract) a positive reaction was observed in the stroma. Since endoglin has been proposed as a possible target for antiangiogenic therapy in tumor patients and our data demonstrate a sizable amount of endoglin in normal vessels and stroma, its clinical use should be carefully reevaluated.
High performance CMOS circuit techniques for the G-4 S/390 microprocessor (1997)

This paper describes the CMOS circuit techniques used in the design of the high performance Generation-4 S/390 microprocessor. Successful system operation at frequencies up to 400 MHz was achieved through careful static circuit design and timing optimization, along with the limited use of dynamic circuits for highly critical functions, and several different clocking/latching strategies for cycle time reduction. A variety of innovative full-custom circuit techniques were used in the dataflow design. Timing-driven synthesis of the control logic provided maximum flexibility with minimum turn-around time, while still matching the performance level set by the custom parts of the design. The on-chip LI cache was designed extensively with self-resetting CMOS (SRCMOS) circuitry to provide a 2.0 ns access time and up to 500 MHz operation.
Two-photon transitions between bound-to-continuum states in AlGaAs/GaAs multiple quantum well (1998)

We have experimentally observed room-temperature exciton resonances resulting from interband two-photon transitions between bound-to-continuum states. The excitons exhibit reduced binding energy and broadened resonances compared to that of excitons resulting from two-photon transitions between bound states. This trend is consistent with our theoretical prediction.
Identification of the binding site for Gqα on its effector Bruton’s tyrosine kinase (1998)

Heterotrimeric G proteins and tyrosine kinases are two major cellular signal transducers. Although G proteins are known to activate tyrosine kinases, the activation mechanism is not clear. Here, we demonstrate that G protein Gqalpha binds directly to the nonreceptor Bruton's tyrosine kinase (Btk) to a region composed of a Tec-homology (TH) domain and a sarcoma virus tyrosine kinase (Src)-homology 3 (SH3) domain both in vitro and in vivo. Only active GTP-bound Gqalpha, not inactive GDP-bound Gqalpha, can bind to Btk. Mutations of Btk that disrupt its ability to bind Gqalpha also eliminate Btk stimulation by Gqalpha, suggesting that this interaction is important for Btk activation. Remarkably, the structure of this TH (including a proline-rich sequence) -SH3 fragment of the Btk family of tyrosine kinases shows an intramolecular interaction. Furthermore, the crystal structure of the Src family of tyrosine kinases reveals that the intramolecular interaction of SH3 and its ligand is the major determining factor keeping the kinase inactive. Thus, we propose an activation model that entails binding of Gqalpha to the TH-SH3 region, thereby disrupting the TH-SH3 intramolecular interaction and activating Btk.
Electropolymerization of ruthenium (bis(1,10-phenanthroline)(4-methyl-4'-vinyl2,2'-bipyridine) complexes through direct attack on the ligand ring system (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectropolymerization of ruthenium (bis(1,10-phenanthroline)(4-methyl-4'-vinyl2,2'-bipyridine) complexes through direct attack on the ligand ring systemThomas F. Guarr and Fred C. AnsonCite this: J. Phys. Chem. 1987, 91, 15, 4037–4043Publication Date (Print):July 1, 1987Publication History Published online1 May 2002Published inissue 1 July 1987https://pubs.acs.org/doi/10.1021/j100299a022https://doi.org/10.1021/j100299a022research-articleACS PublicationsRequest reuse permissionsArticle Views357Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
T Cell CD3ζ Deficiency Enables Multiorgan Tissue Inflammation (2013)

Although a population of T cells with CD3ζ chain deficiency has been found in patients with systemic lupus erythematosus, rheumatoid arthritis, cancer, and infectious disease, the role of CD3ζ chain in the disease pathogenesis remains unknown. To understand the contribution of CD3ζ deficiency to the expression of organ injury, we have performed the following studies. We used CD3ζ-deficient mice to investigate the role of CD3ζ in the pathogenesis of organ tissue inflammation. We found that the CD3ζ(-/-) mice can spontaneously develop significant organ inflammation that can be accelerated following the administration of polyinosinic:polycytidylic acid or allogeneic cells (graft versus host). T cells from CD3ζ(-/-) mice display increased expression of the adhesion molecules CD44 and CCR2 and produce increased amounts of IFN-γ blockade, which mitigates tissue inflammation. Our results demonstrate that CD3ζ deficiency bestows T cells with the ability to infiltrate various tissues and instigate inflammation. Decreased CD3ζ expression noted in T cells from various diseases contributes independently to tissue inflammation and organ damage. Approaches to restore CD3ζ expression of the surface of T cells should be expected to mitigate tissue inflammation.
A look at motion in the frequency domain (1983)

Neonatal mice may not mount an adequate Th1 type immune response due to a significantly lower expression of Th1-type immune components as compared to adult mice, even when forced into a Th1-prone environment.
Infrared Absorption Spectra of Inorganic Coördination Complexes. I. The Nature of Chelation Bonding in Bis-(glycino)-copper(II) Monohydrate and Bis-(glycino)-nickel(II) Dihydrate<sup>1</sup> (1955)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInfrared Absorption Spectra of Inorganic Coördination Complexes. I. The Nature of Chelation Bonding in Bis-(glycino)-copper(II) Monohydrate and Bis-(glycino)-nickel(II) Dihydrate1D. N. Sen, San-Ichiro Mizushima, Columba Curran, and J. V. QuaglianoCite this: J. Am. Chem. Soc. 1955, 77, 1, 211–212Publication Date (Print):January 1, 1955Publication History Published online1 May 2002Published inissue 1 January 1955https://pubs.acs.org/doi/10.1021/ja01606a078https://doi.org/10.1021/ja01606a078research-articleACS PublicationsRequest reuse permissionsArticle Views914Altmetric-Citations73LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Oxidation with Lead(IV). I. Mechanism of the Decarboxylation of Pentanoic Acids (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOxidation with Lead(IV). I. Mechanism of the Decarboxylation of Pentanoic AcidsJay K. KochiCite this: J. Am. Chem. Soc. 1965, 87, 16, 3609–3619Publication Date (Print):August 1, 1965Publication History Published online1 May 2002Published inissue 1 August 1965https://pubs.acs.org/doi/10.1021/ja01094a015https://doi.org/10.1021/ja01094a015research-articleACS PublicationsRequest reuse permissionsArticle Views1158Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts