gebhart/patrepeval huggingface dataset:
Solvate Ionic Liquid Electrolyte for Li–S Batteries (2013)

Innovation in the design of electrolyte materials is crucial for realizing next-generation electrochemical energy storage devices such as Li–S batteries. The theoretical capacity of the S cathode is 10 times higher than that of conventional cathode materials used in current Li–ion batteries. However, Li–S batteries suffer from the dissolution of lithium polysulfides, which are formed by the redox reaction at the S cathode. Herein, we present simple solvate ionic liquids, glyme–Li salt molten complexes, as excellent electrolyte candidates because they greatly suppress the dissolution of lithium polysulfides. The molten complexes do not readily dissolve other ionic solutes, which leads to the stable operation of the Li–S battery over more than 400 cycles with discharge capacities higher than 700 mAh g-sulfur−1 and with coulombic efficiencies higher than 98% throughout the cycles. Such high performance has not been realized to the best of our knowledge. Furthermore, the addition of a nonflammable fluorinated solvent, which does not break the solvate structure of the glyme–Li salt molten complexes, greatly enhances the power density of the Li–S battery. The strategic design of electrolyte properties provides opportunities for the development of new electrochemical devices with many different electrode materials.
Holiday at Mentone. 1888 (1977)

The sea may be as lifeless as a hanged man, as if a rolling thing was all it wanted to complete its calm...
Effect of aminophylline on postischemic edema and brain damage in cats. (1988)

We attempted to ameliorate postischemic edema and brain tissue injury in cats by administering aminophylline to reduce the reactive hyperemia that supposedly aggravates both these sequelae. Forty-one cats were subjected to 1 hour of middle cerebral artery occlusion and were killed after 3 hours, 3 days, or 14 days of recirculation; one half of the cats received 0.916 ml/kg of a 25 mg/ml solution of aminophylline by infusion at a constant rate via the femoral vein starting 10 minutes before release of the occlusion and continuing for 5 minutes after initiation of recirculation; the other half received saline. Regional cerebral blood flow was monitored by the hydrogen clearance method and water content was evaluated by specific gravity measurements after 3 hours of recirculation; the status of the blood-brain barrier was assessed with Evans blue tracer. Morphologic observations were carried out in cats killed after 3 or 14 days of recirculation. Aminophylline-treated cats killed after 3 hours of recirculation showed significantly reduced hyperemia and edema and no leakage of Evans blue, which was present in all untreated cats killed after 3 hours or 3 days of recirculation. Morphologic observations revealed conspicuously more severe ischemic brain tissue damage in the untreated than in the aminophylline-treated cats after 3 and 14 days of recirculation. Our studies indicate the beneficial effect of administration of aminophylline in the amelioration of postischemic edema and brain tissue injury, which is presumably achieved by reduction of reactive hyperemia.
Final report Part 2 - socio cultural assessment (2000)

While the Road Sector Institutional Support Technical Assistance Project will examine rehabilitation options to minimize the need for ongoing road maintenance, the environmental assessment considers the potential environmental effects of the project on social, cultural, and economic resources, in a two-volume report covering the Katunguru - Kasese - Fort Portal Road, and Kasese - Kilembe Road - Equator Road segments. Measures to mitigate adversity are: To reduce the effects of road widening, those works within road reserves, should be conducted after harvest period, and, for those outside road reserve, compensation should be granted to affected landowners. As a result of earthworks, borrow pits will be available for waste, and spoil disposal, in an effort to reduce hydrological damage. Noise, dust, and safety risks will be minimized by limiting working hours to daytime schedules, enforcing control measures to reduce traffic speed, and, securing access to pedestrians, and cyclists through adequate traffic signals, and temporary diversions. During construction, health facilities will be available on-site, to ensure the well-being of local workforce, and communities. Maintenance of drainage infrastructure will be pursued, to avoid potential flooding of adjacent properties.
Image modality classification (2011)

Automatic recognition or classification of medical image modality can provide valuable information for medical image retrieval and analysis. In this paper, we discuss an application of SVM ensemble classifiers to the problem, and explore a confidence indicator based late fusion method to resolve ambiguity across competing classes. Using a matrix of closeness and a set of additional fusion rules, the proposed method improves the classification performance by only subjecting likely misclassified samples to a text-based classifier followed by additional fusion of both image-based classification and text-based classification results. An empirical evaluation using standard ImageClef2010 Medical Retrieval data show very promising performance for the proposed approach.
Direct Reprogramming of Human Fibroblasts to Hepatocyte-Like Cells by Synthetic Modified mRNAs (2014)

Direct reprogramming by overexpression of defined transcription factors is a promising new method of deriving useful but rare cell types from readily available ones. While the method presents numerous advantages over induced pluripotent stem (iPS) cell approaches, a focus on murine conversions and a reliance on retroviral vectors limit potential human applications. Here we address these concerns by demonstrating direct conversion of human fibroblasts to hepatocyte-like cells via repeated transfection with synthetic modified mRNAs. Hepatic induction was achieved with as little as three transcription factor mRNAs encoding HNF1A plus any two of the factors, FOXA1, FOXA3, or HNF4A in the presence of an optimized hepatic growth medium. We show that the absolute necessity of exogenous HNF1A mRNA delivery is explained both by the factor's inability to be activated by any other factors screened and its simultaneous ability to strongly induce expression of other master hepatic transcription factors. Further analysis of factor interaction showed that a series of robust cross-activations exist between factors that induce a hepatocyte-like state. Transcriptome and small RNA sequencing during conversion toward hepatocyte-like cells revealed global preferential activation of liver genes and miRNAs over those associated with other endodermal tissues, as well as downregulation of fibroblast-associated genes. Induced hepatocyte-like cells also exhibited hepatic morphology and protein expression. Our data provide insight into the process by which direct hepatic reprogramming occurs in human cells. More importantly, by demonstrating that it is possible to achieve direct reprogramming without the use of retroviral gene delivery, our results supply a crucial step toward realizing the potential of direct reprogramming in regenerative medicine.
Treatment of distal tibial fracture with MIPO techniques (2011)

Objective To explore the clinical application and value of MIPO technique in treating distal tibial fracture.Methods During February 2007 and January 2009,27 patients with distal tibial fractures were treated by MIPO technique using LCP.Based on the AO fracture classification system,7 patients were classified into A2,9 into A3,7 into B2 and 4 into C1.The mean age was 43 years old ranging from 26 to 72 years old.Results The mean follow-up duration was 12 months ( between 4 and 21 months ).According to the Johner-Wruhs score classification system,all the patients were well treated,with excellent efficacy in 19 patients,good in 7 patients and acceptable in 1 patient.No infection or skin putrescence occurred.Conclusion MIPO technique is an ideal measure to treat distal tibial fracture with the advantages such as less incision,higher healing rate,nicer appearance,more stable fixation,less tissue infection,earlier functional exercise and weightbearing activity.

Key words: 
Minimally invasive;  Internal fixation;  Tibia;  Fracture
PERSON-ORGANIZATION FIT AND PERSON-JOB FIT IN EMPLOYEE SELECTION: A REVIEW OF THE LITERATURE (2004)

This manuscript reviews the recent advancement of the research on person-organization (PO) fit and person-job (P-J) fit, the two most extensively studied fit constructs in th ee mployee selection context. First, various conceptualizations of person-environment (P-E) fit, which is an overarching concept of P-O fit and P-J fit, are reviewed. Then, research on P-O fit and P-J fit is reviewed with greater emphasis on th ee mployee selection context. Finally, some unexplored topics in this field are discussed and suggestions for future research are offered.
Differences in immune responses to a low-molecular compound in three guinea-pig strains. (1997)

The present experiments were undertaken to clarify the differences in humoral and cellular immune responses to a low-molecular compound, sodium 2,4,6-trinitrobenznnesul fonate dihydrate (TNBS) in guinea-pig strains. Guinea pigs of three different strains, Hartley, Strain 2 and Strain 13, were immunized subcutaneously with TNBS (3 mg/body) 2 or 3 times a week, 9 times in total. Humoral immune responses to TNBS were assessed by passive cutaneous anaphylaxis (PCA) and Arthus reaction, and cellular immune response was assessed by delayed-type hypersensitivity (DTH). Hartley guinea pigs showed high humoral immune responses to TNBS, whereas Strain 2 and 13 guinea pigs showed low responses. Strain 2 guinea pigs displayed high cellular immune response to TNBS, and Strain 13 displayed low cellular immune responses. These results suggest that the pattern of humoral immune response to TNBS does not correlate with that of the cellular immune responses to TNBS for Strain 2 and Hartley guinea pigs.
Requirement of sense transcription for homology‐dependent virus resistance and <i>trans‐</i>inactivation (1997)

Transgenic tobacco plants carrying post‐transcriptionally silenced (L) or conditionally high‐expressing (H c ) cauliflower mosaic virus 35S promoter:β‐glucuronidase ( GUS ) transgenes were tested for their ability to support replication of a potato virus X derivative with an inserted GUS coding sequence (PVX.GUS). PVX.GUS accumulated to high levels on non‐transformed tobacco. In contrast, both L and H c tobacco were resistant to PVX.GUS. Another line, 271, carries a 35S‐driven transgene that can down‐regulate transcription from any other 35S promoter in trans . When the 271 locus was introduced into the L and H c lines, virus resistance was suppressed. The L tobacco line also trans ‐inactivated transient GUS expression from an extra‐chromosomal T‐DNA delivered by Agrobacterium . This trans‐ inactivation was not observed when the 271 locus was present. In addition, it was found that the 271 locus suppressed the virus resistance normally conferred by a 35S‐driven transgene derived from the PVX replicase open reading frame. These results indicate that sense transcription is required for a transgene to condition homology‐dependent virus resistance and post‐transcriptional trans‐ inactivation.
Atrial Extracellular Matrix Remodeling and the Maintenance of Atrial Fibrillation (2004)

Atrial extracellular matrix remodeling manifested by the selective downregulation of TIMP-2 along with upregulation of MMP-2 and CVF-I in the atrium is associated with the development of sustained atrial fibrillation in patients with cardiomyopathy and heart failure.
Transmitter utilising bandpass delta-sigma modulator and switching mode power amplifier (2004)

In this paper a concept of a transmitter using delta-sigma modulation and switching mode power amplifier is presented. The specifications of a WCDMA base station transmitter are as an objective. Using a delta-sigma modulation in a D/A conversion, most of the nonlinearities of a multi-bit D/A converter are avoided. In addition the 1-bit output signal of the delta-sigma modulator is suitable for power efficient switching mode power amplifiers. The use of the images of the signal is studied as a method to reduce the required sampling frequency. The problems and possible solutions in implementing a wideband transmitter with this topology are discussed as well.
Development of a Novel Robotically Effected Plastic Foam Sculpting System for Rapid Prototyping and Manufacturing (2007)

This thesis presents the development of a novel robotically effected plastic foam sculpting system for rapid prototyping and manufacturing purposes. The developed system is capable of rapidly sculpting physical objects out of expanded and extruded polystyrene using an electrically heated Nichrome sculpting tool. An overview of current conventional rapid prototyping systems indicated that the main disadvantages lie in the limited size of objects which can be built, the relatively long time involved to produce one part and the high cost of the systems and materials. An extensive literature and technology review was conducted on work which was similar to the novel system presented in this thesis. The literature provided many good ideas which could be applied. Two sections of experimental work were conducted. The first was aimed at simply proving the concept of robotically effected sculpting of plastic foams. A crude procedure was developed which proved to be rather tedious and manual, especially in terms of generating the tool paths. Qualitative observations of the cut surfaces were used to change the testing parameters to explore their effects and discover which parameters produced accurate and smooth sculpted surfaces. 12 tests were documented and proved that the sculpting of satisfactory surfaces was achievable. The second section of experimental work involved developing the aforementioned crude procedure to make it more automated, especially in terms of the tool path generation and optimisation step. An innovative five step procedure was developed which if followed can produce accurately sculpted artefacts using CAD models of the artefacts as the primary input. Two artefacts were successfully sculpted using the developed procedure. The first was a simple lofted surface; the CAD model of which was created in SolidWorks. The second artefact was a patient customised medical radiation therapy head and neck support; the CAD model of which was created by scanning the back of the author's head and neck with a 3D scanner. The sculpted support fitted the author perfectly. The implementation of the procedure in the two tests highlighted several points including the speed in which the whole process can be carried out. The time taken from the scanning of the authors head and neck with the 3D scanner through to the physical sculpted artefact, was a mere 80 minutes; of which only 13 minutes was consumed in the actual setup and sculpting step! This is extremely quick when compared to conventional rapid prototyping systems and CNC milling. Several areas of future work were outlined and included, tool and fixture design, automation and integration of the system procedure, tool pathing strategy for foam cutting and robot control system issues. The work presented in this thesis provides an excellent foundation for future development of the robotic foam sculpting system.
Polymerization of Internal Olefins (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPolymerization of Internal OlefinsB. C. Anderson, C. L. Hoover, and O. VoglCite this: Macromolecules 1969, 2, 6, 686–687Publication Date (Print):November 1, 1969Publication History Published online1 May 2002Published inissue 1 November 1969https://pubs.acs.org/doi/10.1021/ma60012a027https://doi.org/10.1021/ma60012a027research-articleACS PublicationsRequest reuse permissionsArticle Views262Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Mapping Flowering Time Gene Homologs in Soybean and Their Association with Maturity (<i>E</i>) Loci (2003)

Time of flowering is a quantitatively inherited character of agronomic importance in soybean [ Glycine max (L.) Merr.]. The genetics of flowering time has been extensively studied in the model plant Arabidopsis thaliana (L.) Heynh. The first objective of this study was to map onto the soybean genetic map orthologous genes known to be involved in photoperiod recognition and time of flowering in A. thaliana and compare their location with previously mapped flowering time quantitative trait loci (QTL). The second objective was to associate the mapped homologs with maturity ( E ) loci by means of near isogenic lines (NILs). Three single‐cross soybean populations, consisting of two recombinant inbred line (RIL) populations and one F 2 population, were used in the mapping study. One RIL population, IX132, was developed by crossing PI 317.336 and ‘Corsoy’; the second, IX136, by crossing PI 317.334B and Corsoy. Both plant introductions have been reported to be photoperiod‐insensitive while the Corsoy parent has been reported to be photoperiod‐sensitive. The RIL populations were previously used to map QTL for flowering time, maturity, and photoperiod‐insensitivity in soybean. The F 2 population was developed from an interspecific cross between G max (breeding line A81‐356022) and G. soja (PI 468.916). Eighteen soybean cDNA clones, identified by BLAST to have high similarities with 18 previously cloned A thaliana flowering time genes, were used as probes in this study. Ten of the 18 cDNA clones were mapped. The cDNAs were mapped onto linkage groups (LGs) A2 ( CRY2 ), B1 and H ( COL1 ), A1 and B2 ( PHYA ), C1 ( DET1 and LD ), D2 ( AP2 ), E and K ( PHYB ), F ( COL2 ), L ( FCA ), and Q ( CCA1 ). None of the cDNAs were directly associated with previously mapped QTL for flowering time. Forty‐one NILs and two recurrent parents (RPs) were used in the association study. Analyses of these candidate genes using contrasting NILs showed that the FCA homolog was associated with maturity locus E3 That FCA is a strong gene candidate for maturity locus E3 is further supported by map position and phenotypic data. Analyses of NILs suggest that the soybean homolog PHYB may be associated with maturity locus E1 However, current data show they mapped in different LGs.
Human cytomegalovirus IE86 protein interacts with promoter-bound TATA-binding protein via a specific region distinct from the autorepression domain (1993)

The major immediate-early gene of human cytomegalovirus encodes several isoforms of an immediate-early protein which has distinct transcriptional regulatory properties. The IE86 isoform autorepresses the major immediate-early promoter by directly binding the cis repression signal element located between the TATA box and the mRNA cap site. In addition to this activity, IE86 stimulates other viral and cellular promoters. One mechanism by which eukaryotic regulatory proteins are thought to stimulate transcription is by contacting one or more general transcription factors. We show that the IE86 protein physically interacts with the DNA-binding subunit (TATA-binding protein) human transcription factor IID via the TATA-binding protein-contacting domain in the N terminus of IE86. In a mobility shift assay, IE86 was also observed to stabilize the binding of TATA-binding protein to promoter DNA. The domains within IE86 responsible for mediating transactivation and repression functioned independently. These experiments thus demonstrate the elegant ability of human cytomegalovirus to join different protein domains to produce distinct multifunctional proteins.
STANMORE CUSTOM-MADE EXTENDIBLE DISTAL FEMORAL REPLACEMENTS (1997)

The use of extendible distal femoral replacements is a relatively new treatment alternative for malignant bone tumours in growing individuals. Although their appearance was widely appreciated, questions about functional practicality and longevity remain unclear. With longer follow-up, advantages of immediate functional restoration and beneficial psychological aspects seem to be overshadowed by an increase in complications such as aseptic loosening, infection or prosthetic failure. We have reviewed 18 children with such tumours who were treated between 1983 and 1990 by custom-made Stanmore extendible distal femoral replacements. Four died from metastatic disease within 2.5 years of operation and two required amputation for local recurrence or chronic infection. The remaining 12 patients were followed for a mean of 8.7 years (6 to 13.2). A mean total lengthening of 5.2 cm was achieved, requiring, on average, 4.3 operations. Using the Musculoskeletal Tumor Society rating score the functional result at review was, on average, 77% of the expected normal function, with seven patients achieving ≥ 80%. Revision of the prosthesis was required in ten patients, in six for aseptic loosening, at a mean of 6.2 years after the initial procedure.
Phishing Detection by Determining Reliability Factor Using Rough Set Theory (2013)

Phishing is a common online weapon, used against users, by Phishers for acquiring a confidential information through deception. Since the inception of internet, nearly everything, ranging from money transaction to sharing information, is done online in most parts of the world. This has also given rise to malicious activities such as Phishing. Detecting Phishing is an intricate process due to complexity, ambiguity and copious amount of possibilities of factors responsible for phishing. Rough sets can be a powerful tool, when working on such kind of Applications containing vague or imprecise data. This paper proposes an approach towards Phishing Detection Using Rough Set Theory. The Thirteen basic factors, directly responsible towards Phishing, are grouped into four Strata. Reliability Factor is determined on the basis of the outcome of these strata, using Rough Set Theory. Reliability Factor determines the possibility of a suspected site to be Valid or Fake. Using Rough set Theory most and the least influential factors towards Phishing are also determined.
Novel method for coupling of poly(ethyleneglycol) to carboxylic acid moieties of proteins (1996)

Lack of toxicity, excellent solubility and superb biocompatibility make polyethylene glycol (PEG) one of the most popular modifiers of biologicals. The most common method for attachment of PEG is based on modification of amino groups of proteins with methoxy- or succinimide-derivatives of PEG. In the case of proteins with amino groups important for biological activity, this modification can lead to inactivation of proteins. A new strategy for covalent attachment of PEG to carboxylic groups of proteins using O,O-bis-(2-aminopropyl)polyethylene glycol and carbodiimide/N-hydroxysuccinimide-mediated reaction was developed. The reaction is carried out under mild aqueous conditions. The attached PEG serves as a hydrophilic spacer for further bioconjungation with biomolecules and haptens. Lipase from Candida rugosa was used as a model protein. Characteristic data of the modified protein such as activity, isoelectric points and stability were compared with that of the unmodified protein.