gebhart/patrepeval huggingface dataset:
Air quality and wind relationships on the central coast of New South Wales (1990)

Measurements of sulfur dioxide (SO2), nitrogen oxides (NOx = N O+ NO:), suspended particulates, aerosol back-scattering (an indication of visibility), wind speed and wind direction were made over a two year period (December 1985 to November 1987) at Lake Munmorah Primary School (NSW) in support of a study analysing relationships between air quality and asthma in school children. The results establish that clean air guidelines adopted by the NSW State Pollution Control Commission are not violated by SO2 or suspended particulate concentrations measured, or by annual average nitrogen dioxide (NO2) measurements.
Positron Emission Tomography Imaging Demonstrates Correlation between Behavioral Recovery and Correction of Dopamine Neurotransmission after Gene Therapy (2009)

In vivo gene transfer using viral vectors is an emerging therapy for neurodegenerative diseases with a clinical impact recently demonstrated in Parkinson's disease patients. Recombinant adeno-associated viral (rAAV) vectors, in particular, provide an excellent tool for long-term expression of therapeutic genes in the brain. Here we used the [(11)C]raclopride [(S)-(-)-3,5-dichloro-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-hydroxy-6-methoxybenzamide] micro-positron emission tomography (PET) technique to demonstrate that delivery of the tyrosine hydroxylase (TH) and GTP cyclohydrolase 1 (GCH1) enzymes using an rAAV5 vector normalizes the increased [(11)C]raclopride binding in hemiparkinsonian rats. Importantly, we show in vivo by microPET imaging and postmortem by classical binding assays performed in the very same animals that the changes in [(11)C]raclopride after viral vector-based enzyme replacement therapy is attributable to a decrease in the affinity of the tracer binding to the D(2) receptors, providing evidence for reconstitution of a functional pool of endogenous dopamine in the striatum. Moreover, the extent of the normalization in this non-invasive imaging measure was highly correlated with the functional recovery in motor behavior. The PET imaging protocol used in this study is fully adaptable to humans and thus can serve as an in vivo imaging technique to follow TH + GCH1 gene therapy in PD patients and provide an additional objective measure to a potential clinical trial using rAAV vectors to deliver l-3,4-dihydroxyphenylanaline in the brain.
Low-loss photonic crystal fibers (2002)

The lowest loss has been achieved in two types of photonic crystal fibre (PCF) due to an improvement of fabrication process. Optical loss at 1.55 /spl mu/m wavelength was 1 dB/km and the Rayleigh scattering coefficient was 2 dB/km /spl mu/m/sup 4/ in the type 2 PCF. These results suggest a possibility of low-loss PCF comparable to that of conventional single-mode fibers.
Synthesis of renewable high-density fuels using cyclopentanone derived from lignocellulose (2013)

By the combination of solvent-free aldol condensation and one-step hydrodeoxygenation under mild reaction conditions, a high-density (0.866 g mL(-1)) bicyclic C10 hydrocarbon was synthesized in high overall yield (up to 80%) using cyclopentanone derived from lignocellulose.
Early Intervention, Brain Plasticity, and the Prevention of Autism (2009)

Includes descriptive metadata provided by producer in MP4 file: Kennedy Center - Videos - Early Intervention, Brain Plasticity, and the Prevention of Autism
Neuropathic pain: are we out of the woods yet? (2006)

Patients suffering from neuropathic pain continue to pose challenges in clinical practice. This descriptive review discusses the continuing debate on the definition and concerns about increasing incidence of neuropathic pain. The clinical features of neuropathic pain are outlined, and the current understanding of the possible mechanisms of neuropathic pain is highlighted. Current management strategies are reviewed, and future advances in our understanding of the mechanisms, accurate clinical diagnosis and more effective treatment strategies are eagerly awaited.
Extension of the Bambus[<i>n</i>]uril Family: Microwave Synthesis and Reactivity of Allylbambus[<i>n</i>]urils (2013)

Microwave irradiations allow the preparation of unsaturated bambusurils in 85% yield compared to 20% yield under classical reaction conditions. Five new bambusurils were synthesized including unsaturated derivatives Allyl(8)BU[4] and Allyl(12)BU[6] bearing diallylglycoluril units. The reactivity of Allyl(8)BU[4] was tested in a variety of organic reactions showing that this macrocycle acts as a classical double bond-bearing product. The first monofunctionalized bambusuril Allyl(7)HepBU[4] prepared by a cross metathesis reaction is also reported.
The preparation of an alkali-soluble collagen from demineralized bone (1971)

Ossein was solubilized by the action of alkali and a resulting high-molecular-weight fraction isolated. The chemical and physical properties of this fraction were studied and compared with those of an acid-soluble collagen prepared from calf skin by conventional techniques. From the results it is concluded that the alkali-soluble protein exhibits only minor differences from acid-soluble collagen, and that these differences can be ascribed for the most part to a decrease in the inter- and intramolecular cross-linking.
Cover Picture: ChemBioChem 12/2002 (2002)

The cover picture shows a schematic representation of how collagen-induced arthritis, a model for rheumatoid arthritis, is induced in mice by immunization with type II collagen. Immunization leads to presentation of glycopeptide antigens by major histocompatibility complex (MHC) molecules to T cells. By using a panel of synthetic glycopeptides, the T cells were found to recognize the galactose moiety attached to hydroxylysine 264 in the type II collagen fragment CII256-270. These results, and knowledge of which amino acids anchor CII256-270 in the cleft of the class II MHC molecule, were used to generate the structural model of the glycopeptide–MHC complex also shown in the cover picture. Further details can be found in the article by Kihlberg and co-workers on p. 1209 ff. (We thank Björn Holm and Andreas Larsson for assistance in the preparation of the cover picture.)
Evidence for widespread infection of wild rats with hepatitis E virus in the United States. (1999)

Hepatitis E is an important medical pathogen in many developing countries but is rarely reported from the United States, although antibody to hepatitis E virus (anti-HEV) is found in > 1% of U.S. citizens. Zoonotic spread of the virus is suspected. Sera obtained from 239 wild rats trapped in widely separated regions of the United States were tested for anti-HEV. Seventy-seven percent of rats from Maryland, 90% from Hawaii, and 44% from Louisiana were seropositive for anti-HEV. Rats from urban as well as rural areas were seropositive and the prevalence of anti-HEV IgG increased in parallel with the estimated age of the rats, leading to speculation that they might be involved in the puzzling high prevalence of anti-HEV among some U.S. city dwellers. The discovery of a in rats in the United States and the recently reported discovery that HEV is endemic in U.S. swine raise many questions about transmission, reservoirs, and strains of HEV in developed countries.
Nucleation-Controlled Growth of Nanoparticles by Atomic Layer Deposition (2012)

We demonstrate a method for growing metal nanoparticles (NPs) by atomic layer deposition (ALD) with the ability to vary aerial density and NP size using nucleation control. Self-assembled monolayers (SAMs) preadsorbed on the substrate serve as a template for subsequent growth of the NPs by ALD. Defects in the SAM resulting from incomplete formation time in solution are shown to act as nucleation sites for Pt. The strategy is demonstrated experimentally using ALD of Pt from a metal organic Pt precursor and O2 counter reactant on silicon dioxide surfaces pretreated with octadecyltrichlorosilane SAMs. The aerial density and mean diameter of the Pt NPs are controlled by changing the SAM dip time and the number of ALD cycles. An isothermal nucleation model was developed in which several nucleation behaviors were considered in comparison with experimental data. A model incorporating nucleation incubation provided the best fit to the data.
Flow control of centrifugal jet-flap blowers for air-cushion vehicles (1979)

Air-cushion vehicles and surface-effect ships may require some form of dynamic lifting air control. An experimental investigation was carried out to demonstrate both the steady-state and the dynamic flow control characteristics at constant pressure of a model (32.7 in. diameter) double-inlet, double-width centrifugal blower at low tip speed ( — 250 ft/s). The impeller was designed with fixed backward-curved jet-flap airfoil blades and the housing was equipped with rotatable jet-flap inlet guidevanes. The flow control test was carried out at constant pressure, starting from the maximum efficiency (85%) point of the basic blower. Over 50% negative flow control was achieved with the jet-flap inlet guidevanes and 50% positive flow control was obtained with the impeller jet-flap, with a jet-flap supply flow of only 2.8%. Frequency response tests were carried out on the impeller jet-flap flow control system with a rotating butterfly. The pressure amplitude ratio was found to remain above - 3 dB for all frequencies tested, up to the maximum 12.5 Hz, where the phase angle approached 90 deg. Nomenclature al — blower output pressure amplitude at variable frequency, psf al * = quasisteady output pressure amplitude, psf a2 = blower jet-flap input pressure amplitude at variable frequency, psf a2 * = quasisteady input pressure amplitude, psf b =
Applying the Service-Oriented Architecture for Network Discovery and Selection in the Next Generation Wireless Mobile Networks (2009)

The next generation wireless mobile network will be a heterogeneous networking environment consisting of various networks with heterogeneous implementations. Discovering and selecting the optimal networks for delivering an end-to-end networking service has significant impact on the service quality offered to applications. One of the main challenges to network discovery and selection is the heterogeneity of the coexisting networks in such networking environments. A key to solving this problem lies in flexible and effective interactions among the heterogeneous networks, the network control plane, and various user equipments. The Service-Oriented Architecture (SOA) is gaining high attention and acceptance in IT industry due to its power for coordinating heterogeneous systems for supporting various application requirements. The SOA offers a promising solution to network discovery and selection. In this paper, we investigate applying the SOA principles in wireless networking environments and propose a service-oriented architecture for network discovery and selection. The developed architecture and technologies are network-independent; thus are applicable to various network systems in heterogeneous wireless mobile networking environments.
Predicting Employee Attrition along with Identifying High Risk Employees using Big Data and Machine Learning (2020)

"It takes a lot of time and energy to build a great employee and only a second to lose one." Employee turnover is a perennial challenge faced by all the major companies across the globe, performance of a company is directly proportional to the quality of employees retained by them. Whenever a good employee quits the organization it leads to financial losses, gaps in company's execution capability, re-recruiting costs and loss of productivity. The success of a company lies not only in impeding the attrition rate but also in retaining the right talent. According to NASSCOM, the global employee churn rate as of 2019 is 18-20 percent, which is what makes it necessary to alleviate the business risks associated with the turnover using statistical analysis. This research aims to foresee potential attrition (specifically in the B.P.O. sector) by mining turnover trends amongst employees and use supervised classification techniques to cluster out vulnerable employees".
Characterization of Modified Nanoscale ZSM-5 Catalyst and Its Application in FCC Gasoline Upgrading Process (2006)

Nanoscale HZSM-5 zeolite was hydrothermally treated with ammonia water at 673 K and then loaded with La2O3 and ZnO. The parent and modified nanoscale HZSM-5 zeolite catalysts were characterized by SEM, XRD, NH3-TPD, IR, and XRF. In the presence of hydrogen, the performance of the modified ZSM-5 catalyst for FCC gasoline upgrading was evaluated in a fixed-bed reactor. The results indicated that the modified catalyst exhibited excellent aromatization activity, isomerization activity, and a strong ability to reduce olefin and sulfur contents in FCC gasoline. Under the given reaction conditions, the average olefin content in FCC gasoline was decreased from 49.6 to 12.8 vol % within 300 h time on stream; the aromatic and paraffin contents in the product were increased from 11.4 and 39.0 vol % to 24.7 and 62.5 vol %, respectively. The modified nanoscale ZSM-5 catalyst reduced sulfur concentration in FCC gasoline by about 78% without gasoline octane number loss.
Rapid isolation of cloned isotype switch variants using fluorescence activated cell sorting (1982)

We have used highly specific, directly fluorescein-conjugated heterologous (conventional) and monoclonal antibodies directed against mouse immunoglobulin isotypes in conjunction with the fluorescence activated cell sorter (FACS) to enrich and clone hybridoma cells producing new immunoglobulin heavy chain constant regions. Each variant retains the parental heavy chain variable region and the parental immunoglobulin light chain; thereby each variant binds the same dansyl (DNS) hapten. These isotype switch variants occur at frequencies of approximately 10-5 to 10-6. We were able to isolate the variants by first sorting for an approximate 1000-fold enrichment of the desired immunoglobulin-producing cells, growing these cells for five to nine days, followed by a second 1000-fold enrichment and direct cell cloning into 96 well culture trays. Clones were screened only 3-5 weeks after the original selection for secretion of dansyl-binding immunoglobulin of the selected isotype. Judicious combination of existing methods permits improved analytical techniques using the cell sorter. These include: first, "red" fluorescence staining of dead cells with ethidium bromide or propidium iodide and using the red fluorescence measurement to exclude dead cells from the green fluorescence selection; and second, the use logarithmic amplification of fluorescence signals, allowing for more succinct selection of fluorescence parameters for sorting.
An Experiment Study for Time Synchronization Utilizing USRP and GNU Radio (2017)

Time synchronization is purposed to make the different time realizations of many objects as same as possible. As an initial study on time synchronization, this paper proposes a wireless time synchronization method utilizing SDR (Software Defined Radio). For the purpose, reference pulses are generated and transmitted by a reference USRP (Universal Software Radio Peripheral) based on GNU Radio. The other USRPs are synchronized to the reference pulses for time synchronization. To evaluate the accuracy of the proposed method, sampled data and synchronization error of each slave USRP are compared.
Morphologic and functional characterization of perforin-deficient lymphokine-activated killer cells (1995)

Mice deficient in perforin, a key mediator of lymphocyte-mediated cytolysis, have recently been generated using the gene knockout technique. CTL and NK cells derived from these mice have been shown to be defective in the granule-dependent cytolytic pathway. To investigate whether the granule-formation process has been altered in these perforin-deficient cytotoxic cells, rendering them defective in using the other granule mediators, we have examined in the present study the morphologic and functional characteristics of perforin-deficient LAK cells. Perforin-deficient LAK cells, similar to wild-type LAK cells, were shown to contain a large number of granules in their cytoplasm. By electron microscopy, the morphology of the granules present in these two cell populations appeared indistinguishable. The complete depletion of perforin in LAK cells derived from perforin gene-knockout mice was further confirmed by immunoelectron microscopy using anti-perforin antiserum. The expression of other cytolytic mediators, present either within the granules (granzymes A and B) or elsewhere (Fas ligand), appeared to be unperturbed, as investigated using the reverse transcription-PCR technique. Like the CTL and NK cells isolated from perforin-deficient mice, perforin-deficient LAK cells could lyse only target cells that express high levels of Fas molecule. Furthermore, these perforin-deficient LAK cells, similar to wild-type LAK cells and a CTL clone, were resistant to perforin-mediated cytolysis.
The glial voltage-gated sodium channel: cell- and tissue-specific mRNA expression. (1992)

Previous electrophysiological and pharmacological studies on central and peripheral glia revealed the presence of voltage-gated Na channels with properties that are similar but not identical to those of neuronal Na channels. Here we report the isolation and characterization of a cDNA encoding the C-terminal portion of a putative glial Na-channel (Na-G) alpha subunit. The amino acid sequence deduced from this cDNA indicates that the Na-G represents a separate molecular class within the mammalian Na-channel multigene family. By Northern blot, RNase protection, and in situ hybridization assays, we demonstrate that, in addition to brain astroglia, the Na-G mRNA is expressed in cultures of Schwann cells derived from dorsal root ganglia or from sciatic nerve. In vivo, the Na-G mRNA is detected not only in brain, dorsal root ganglia, and sciatic nerve, but also in tissues outside the nervous system including cardiac and skeletal muscle and lung. Its level varies according to the tissue and is developmentally regulated. The sequence and expression data concur in designating Na-G as an distinct type of Na channel, presumably with low sensitivity to tetrodotoxin.
Biofilm Formation and Control in Food Processing Facilities (2003)

Microorganisms on wet surfaces have the ability to aggregate, grow into microcolonies, and produce biofilm. Growth of biofilms in food processing environments leads to increased opportunity for microbial contamination of the processed product. These biofilms may contain spoilage and pathogenic microorganisms. Microorganisms within biofilms are protected from sanitizers increasing the likelihood of survival and subsequent contamination of food. This increases the risk of reduced shelf life and disease transmission. Extracellular polymeric substances associated with biofilm that are not removed by cleaning provide attachment sites for microorganisms newly arrived to the cleaned system. Biofilm formation can also cause the impairment of heat transfer and corrosion to metal surfaces. Some of the methods used to control biofilm formation include mechanical and manual cleaning, chemical cleaning and sanitation, and application of hot water.
Improved Icephobic Properties on Surfaces with a Hydrophilic Lubricating Liquid (2015)

Slippery liquid-infused porous surfaces were developed recently for icephobic surface applications. Perfluorinated liquids, silicone oil, hydrocarbon, and water were used as lubricating liquids to form a continuous layer on a suitable substrate to prevent icing. However, ice accretion performances of these surfaces have not been reported previously depending on the type of the lubricant. In this work, fluorinated aliphatics, polyalphaolefin, silicone oil, and decamethylcyclopenta siloxane were used as hydrophobic lubricants; water, ethylene glycol, formamide, and water-glycerine mixture were used as hydrophilic lubricants to be impregnated by hydrophobic polypropylene and hydrophilic cellulose-based filter paper surfaces; ice accretion, drop freezing delay time, and ice adhesion strength properties of these surfaces were examined; and the results were compared to those of the reference surfaces such as aluminum, copper, polypropylene, and polytetrafluoroethylene. An ice accretion test method was also developed to investigate the increase of the mass of formed ice gravimetrically by spraying supercooled water onto these surfaces at different subzero temperatures ranging between -1 and -5 °C. It was determined that hydrophilic solvents (especially a water-glycerine mixture) that impregnated hydrophilic porous surfaces would be a promising candidate for anti-icing applications at -2 °C and 56-83% relative humidity because ice accretion and ice adhesion strength properties of these surface decreased simultaneously in these conditions.
Isolation and characterization of neural progenitor cells from post‐mortem human cortex (2003)

Post-mortem human brain tissue represents a vast potential source of neural progenitor cells for use in basic research as well as therapeutic applications. Here we describe five human neural progenitor cell cultures derived from cortical tissue harvested from premature infants. Time-lapse videomicrography of the passaged cultures revealed them to be highly dynamic, with high motility and extensive, evanescent intercellular contacts. Karyotyping revealed normal chromosomal complements. Prior to differentiation, most of the cells were nestin, Sox2, vimentin, and/or GFAP positive, and a subpopulation was doublecortin positive. Multilineage potential of these cells was demonstrated after differentiation, with some subpopulations of cells expressing the neuronal markers beta-tubulin, MAP2ab, NeuN, FMRP, and Tau and others expressing the oligodendroglial marker O1. Still other cells expressed the classic glial marker glial fibrillary acidic protein (GFAP). RT-PCR confirmed nestin, SOX2, GFAP, and doublecortin expression and also showed epidermal growth factor receptor and nucleostemin expression during the expansion phase. Flow cytometry showed high levels of the neural stem cell markers CD133, CD44, CD81, CD184, CD90, and CD29. CD133 markedly decreased in high-passage, lineage-restricted cultures. Electrophysiological analysis after differentiation demonstrated that the majority of cells with neuronal morphology expressed voltage-gated sodium and potassium currents. These data suggest that post-mortem human brain tissue is an important source of neural progenitor cells that will be useful for analysis of neural differentiation and for transplantation studies.
High output power and high temperature operation of 1.5 mu m DFB-PPIBH laser diodes (1989)

Highly efficient 1.5- mu m distributed-feedback (DFB) p-substrate partially-inverted buried heterostructure laser diodes with a thin active layer developed using a metal-organic chemical vapor deposition technique are discussed. An average slope efficiency of 0.26 mW/mA (quantum efficiency 33%) and maximum slope efficiency of 0.39 mW MW/mA (49%) were achieved. The full width at half maximum in the direction perpendicular to the junction plane of 25 degrees was obtained. A high output power of 77 mW was obtained under CW conditions at room temperature. This laser diode lased up to 120 degrees C, and more than 10 mW was obtained, even at 90 degrees C.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>