gebhart/patrepeval huggingface dataset:
Lone pair electrons minimize lattice thermal conductivity (2012)

As over 93% of the world's energy comes from thermal processes, new materials that maximize heat transfer or minimize heat waste are crucial to improving efficiency. Here we focus on fully dense electrical insulators at the low end of the spectrum of lattice thermal conductivity κL. We present an experimentally validated predictive tool that shows how the high deformability of lone-pair electron charge density can limit κL in crystalline materials. Using first-principles density-functional theory (DFT) calculations, we predict that several ABX2 (groups I–V–VI2) compounds based on the rocksalt structure develop soft phonon modes due to the strong hybridization and repulsion between the lone-pair electrons of the group V cations and the valence p orbitals of group VI anions. In many cases, this creates lattice instabilities and the compounds either do not exist or crystallize in a different structure. Marginally stable ABX2 compounds have anharmonic bonds that result in strong phonon–phonon interactions. We show experimentally how these can reduce κL to the amorphous limit.
A FPGA Embedded Web Server for Remote Monitoring and Control of Smart Sensors Networks (2013)

This article describes the implementation of a web server using an embedded Altera NIOS II IP core, a general purpose and configurable RISC processor which is embedded in a Cyclone FPGA. The processor uses the μCLinux operating system to support a Boa web server of dynamic pages using Common Gateway Interface (CGI). The FPGA is configured to act like the master node of a network, and also to control and monitor a network of smart sensors or instruments. In order to develop a totally functional system, the FPGA also includes an implementation of the time-triggered protocol (TTP/A). Thus, the implemented master node has two interfaces, the webserver that acts as an Internet interface and the other to control the network. This protocol is widely used to connecting smart sensors and actuators and microsystems in embedded real-time systems in different application domains, e.g., industrial, automotive, domotic, etc., although this protocol can be easily replaced by any other because of the inherent characteristics of the FPGA-based technology.
Self-burial of radioactive waste (1999)

The problem of the “self-burial” of radioactive waste into melting rock is solved for a spherical container of finite thickness. The mathematical model constructed, unlike the existing ones, takes into account the thermal losses to the solid rock and to the melt behind the container, as well as the reverse evolution of heat upon solidification of the melt. A calculation for the particular case of self-burial in granite shows that consideration of these factors significantly increases the maximum permissible radius at which the container will remain in the solid state and slows the burial rate.
Brief Communication: Sleep Curtailment in Healthy Young Men Is Associated with Decreased Leptin Levels, Elevated Ghrelin Levels, and Increased Hunger and Appetite (2004)

Short sleep duration in young, healthy men is associated with decreased leptin levels, increased ghrelin levels, and increased hunger and appetite.
X-ray focusing using microchannel plates (1992)

In this paper, we consider the use of lead glass microchannel plates (MCPs) as focusing elements for soft x rays. In particular, we discuss the possible realization of the wide field-of- view `Lobster Eye'' astronomical optics originally proposed by Angel using MCPs with confocal channels of square cross-section. Preliminary laboratory measurements are presented of the point-to-point focusing of both white light and soft x rays by a planar square-pore MCP with 85 (mu) channels. The practical realization of a Lobster Eye x-ray monitor for a possible small satellite mission is considered.
Elements of Meaning in Gesture (2011)

Summarizing her pioneering work on the semiotic analysis of gestures in conversational settings, Geneviève Calbris offers a comprehensive account of her unique perspective on the relationship between gesture, speech, and thought. She highlights the various functions of gesture and especially shows how various gestural signs can be created in the same gesture by analogical links between physical and semantic elements. Originating in our world experience via mimetic and metonymic processes, these analogical links are activated by contexts of use and thus lead to a diverse range of semantic constructions rather as, from the components of a Meccano kit, many different objects can be assembled. By (re)presenting perceptual schemata that mediate between the concrete and the abstract, gesture may frequently anticipate verbal formulation. Arguing for gesture as a symbolic system in its own right that interfaces with thought and speech production, Calbris’ book brings a challenging new perspective to gesture studies and will be seminal for generations of gesture researchers.
IDENTIFICATION OF INHIBITORS FOR RND EFFLUX PUMP OF Pseudomonas aeruginosa USING S TRUCTURE - BASED PHARMACOPHORE MODELING APPROACH (2014)

Objective: Multidrug resistant Pseudomonas aeruginosa possess multiple ways of resistance with the expression of efflux pump proteins as one of the major mechanisms. The efflux proteins of P. aeruginosa belong to the Resistance Nodulation Division (RND) type pumps. The use of efflux pump inhibitors along with the antibiotics could render the efflux pumps inactive thereby increasing the intracellular concentration of the drug. Methods: Phase database compounds were screened against the hypothesis generated for MC-207,110, a known inhibitor and the top fitness compounds were subjected for XP docking analysis. The top five compounds with good interaction and scoring were further analyzed for binding energy by MM-GBSA and drug-likeness property. Results: Based on pharmacophore screening, 500 compounds with good fitness score were shortlisted. By docking the 500 compounds against the protein target, MexB, five best scoring compounds were selected. The compound, ASN05108137 had a maximum dock score of – 8.44 Kcal/mol and -45.12 Kcal/mol docking energy. It exhibited very good binding energy and also a satisfactory drug-likeness. Conclusion: In this study, a structure-based pharmacophore approach was used to identify new inhibitors targeting the MexB efflux pump protein. The compounds were screened based on their similarity to the pharmacophore feature of MC-207,110 and also docking with MexB protein. The compound ASN05108137 showed very high dock score and interactions compared to MC-207110 and also low binding energy. The compound also had a better drug-likeness property thus could be a very potential inhibitor of the efflux pumps.
Effects of the Total Extract and Fractions of<i>Hypericum perforatum</i>in Animal Assays for Antidepressant Activity (1997)

A commercially available extract of the aerial parts of Hypericum perforatum, LI 160, showed pronounced activity in selected animal bioassays. These include the forced swimming test (FST) and the tail suspension test, used to determine antidepressant activity, and tests indicating activity on the central nervous system, such as body temperature and ketamine induced sleeping time. The counteracting effects of drugs known to interfere with the central dopaminergic system strongly suggested that dopamine mediated activity is important for the activity of the extract. Dose-response experiments of the total extract and of fractions rich in flavonoids and napthodianthrones produced inverted U-shaped dose response curves.
Induction of Resistance in Melon to <i>Didymella bryoniae</i> and <i>Sclerotinia sclerotiorum</i> by Seed Treatments with Acibenzolar‐<i>S</i>‐methyl and Methyl Jasmonate but not with Salicylic Acid (2004)

Abstract The plant resistance activator acibenzolar‐ S ‐methyl (BTH), the signalling molecules salicylic acid (SA) and methyl jasmonate (MeJA) were tested by seed treatment for their ability to protect melon seedlings from gummy stem blight and white mould disease caused by the soil‐borne fungal pathogens Didymella bryoniae and Sclerotinia sclerotiorum , respectively. Didymella bryoniae infection on melon seedlings was completely suppressed by MeJA treatment. Necrotic lesions akin hypersensitive response occurred on all inoculated seedlings and prevented pathogen diffusion into healthy tissues. Didymella bryoniae infection was restricted following BTH seed treatment as well, although the percentage of necrotic lesions in comparison with the water soaked lesions was significantly lower than that from MeJA‐induced seedlings. BTH protected melon seedlings against S. sclerotiorum by the occurrence of a high percentage of necrotic lesions. A lower level of resistance was also achieved by MeJA seed treatment. The augmented level of resistance of tissues from BTH and MeJA‐treated seeds was associated with rapid increases in the activity of the pathogenesis‐related proteins chitinase and peroxidase. MeJA also determined a rapid and transient accumulation of lipoxygenase. Moreover, BTH and MeJA treatments determined the differential induction of particular de novo synthesized isoenzymes of these proteins. Results indicate that BTH and MeJA applied to melon seeds may activate on seedlings diverse metabolic pathways leading to the enhancement of resistance against distinct pathogens.
The role of bone marrow mesenchymal stromal cell derivatives in skin wound healing in diabetic mice (2017)

Mesenchymal stromal cells (MSCs) have shown to be a promising tool in cell therapies to treat different conditions. Several pre-clinical and clinical studies have proved that the transplantation of MSCs improves wound healing. Here, we compare the beneficial effects of mouse bone marrow-derived allogeneic MSCs (allo-mBM-MSCs) and their acelullar derivatives (allo-acd-mMSCs) on skin wound healing in Non-Obese Diabetic (NOD) mice. One dose of allo-mBM-MSCs (1×106 cells) or one dose of allo-acd-mMSCs (1X) were intradermally injected around wounds in 8-10 week old female NOD mice. Wound healing was evaluated macroscopically (wound closure) every two days, and microscopically (reepithelialization, dermoepidermal junction, skin appendage regeneration, leukocyte infiltration, vascularization, granulation tissue formation, and density of collagen fibers in the dermis) after 16 days of MSC injection. In addition, we measured growth factors and specific proteins that were present in the allo-acd-mMSCs. Results showed significant differences in the wound healing kinetics of lesions that received allo-acd-mMSCs compared to lesions that received vehicle or allo-mBM-MSCs. In particular, mice treated with allo-acd-mMSCs reached significantly higher percentages of wound closure at day 4, 6 and 8, relative to the allo-mBM-MSCs and vehicle groups (p < 0.05), while wound closure percentages could not be statistically distinguished between the allo-mBM-MSCs and vehicle groups. Also, allo-acd-mMSCs had a greater influence in the skin would healing process. Specifically, they caused a less pronounced inflammatory severe response (p < 0.0001), more granulation tissue formation at an advanced stage (p < 0.0001), and higher density of collagen fibers (p < 0.05) compared to the other groups. Nevertheless, at day 16, both allo-mBM-MSCs and allo-acd-mMSCs revealed a higher effect on the recovery of the quality skin (continuous epidermis; regular dermoepidermal junction and skin appendages) relative to untreated lesions (p < 0.0001), but not between them. On the other hand, ELISA analyses indicated that the allo-acd-mMSCs contained growth factors and proteins relevant to wound healing such as IGF-1, KGF, HGF, VEGF, ANG-2, MMP-1, CoL-1 and PGE2. Compared to allo-acd-mMSCs, the administration of allo-mBM-MSCs is insufficient for wound healing in diabetic mice and delays the therapeutic effect, which maybe explained by the fact that trophic factors secreted by MSCs are critical for skin regeneration, and not the cells per se, suggesting that MSCs may require some time to secrete these factors after their administration.
Simultaneous achievement of high performance and high reliability in a 38/77GHz InGaAs/AlGaAs PHEMT MMIC (2010)

In order to meet the demand for mass production of 77GHz automotive radar systems, a low cost and high performance 38/77GHz AlGaAs/InGaAs PHEMT MMIC transmit amplifier with a multiplier has been realized. The chip is packaged in an inexpensive conventional non-hermetic package. Excellent power performance is demonstrated with a 15dBm output power and 7dB maximum conversion gain from 38 to 76.5GHz. Also, highly reliable RF operation of a bare MMIC chip is obtained with less than 0.7dB reduction in output power during 106 hr at Vd=4V and Ta=25°C in air.
Wound Rotor Induction Generator With Sensorless Control and Integrated Active Filter for Feeding Nonlinear Loads in a Stand-Alone Grid (2008)

This paper describes a vector control scheme for a stand-alone generator based on a wound rotor induction machine with rotor side control. The stand-alone generator refers to an isolated grid feeding a local load. The primary objective of the control scheme is to maintain constant voltage and frequency at the output of the generator irrespective of prime mover speed variation. A novel, simple, and easily implementable sensorless control scheme is proposed. The issue of power quality, which is one of the main concerns of a stand-alone generation system, is also addressed. This is done by incorporating the active filter concept in the control scheme to cancel significant harmonics. A method of unit vector generation for field-oriented control is proposed. A laboratory prototype consisting of back-to-back insulated-gate bipolar transistor converters and a TMS320F240 DSP controller is developed. Detailed experimental results are presented which demonstrate and validate the effectiveness of the proposed scheme.
General incremental sliding-window aggregation (2015)

Stream processing is gaining importance as more data becomes available in the form of continuous streams and companies compete to promptly extract insights from them. In such applications, sliding-window aggregation is a central operator, and incremental aggregation helps avoid the performance penalty of re-aggregating from scratch for each window change. This paper presents Reactive Aggregator (RA), a new framework for incremental sliding-window aggregation. RA is general in that it does not require aggregation functions to be invertible or commutative, and it does not require windows to be FIFO. We implemented RA as a drop-in replacement for the Aggregate operator of a commercial streaming engine. Given m updates on a window of size n , RA has an algorithmic complexity of O ( m + m log ( n/m )), rivaling the best prior algorithms for any m . Furthermore, RA's implementation minimizes overheads from allocation and pointer traversals by using a single flat array.
Measurement of Carbon Concentration in Polycrystalline Silicon Using FTIR (1991)

The carbon concentration in polycrystalline silicon produced via the Siemens process, the hydrogen reduction of trichlorosilane, was evaluated using FTIR. Samples measured included: as grown polycrystalline silicon, high‐temperature annealed polycrystalline silicon, and float zone refined single‐crystalline silicon. It was found that infrared measurements made on high‐temperature annealed polycrystalline silicon samples display similar carbon concentrations as those obtained on float zone refined single‐crystalline silicon samples. Little, if any, evidence exists for the occurrence of significant amounts of interstitial carbon in low carbon concentration polycrystalline silicon material. High‐temperature annealing of polycrystalline silicon results in improved spectrum quality, and therefore, reduces the detection limit and improves the accuracy of the carbon measurement in polycrystalline silicon. A liquid helium sample Dewar was successfully used for cryogenic temperature measurement resulting in further improvement in sensitivity.
Foodborne enterotoxigenic Escherichia coli: detection and enumeration by DNA colony hybridization (1983)

Four methods were compared for detecting heat-labile toxin production by Escherichia coli: DNA colony hybridization, two enzyme-linked immunosorbent assays, and the mouse Y-1 adrenal cell reaction. Although results of the methods were in general agreement, there were some differences in specificity and sensitivity. DNA colony hybridization was used to detect and enumerate enterotoxigenic E. coli isolates in artificially contaminated food without enrichment. Sensitivity level was 100 cells per g.
Active privilege management for distributed access control systems (2021)

The last decade has seen the explosive uptake of technologies to support true Internet-scale distributed systems, many of which will require security. The policy dictating authorisation and privilege restriction should be decoupled from the services being protected: (1) policy can be given its own independent language syntax and semantics, hopefully in an application independent way; (2) policy becomes portable – it can be stored away from the services it protects; and (3) the evolution of policy can be effected dynamically. Management of dynamic privileges in wide-area distributed systems is a challenging problem. Supporting fast credential revocation is a simple example of dynamic privilege management. More complex examples include policies that are sensitive to the current state of a principal, such as dynamic separation of duties. The Open Architecture for Secure Interworking Services (OASIS), an expressive distributed role-based access control system, is traced to the development of the Clinical and Biomedical Computing Limited (CBCL) OASIS implementation. Two OASIS deployments are discussed – an Electronic Health Record framework, and an inter-organisational distributed courseware system. The Event-based Distributed Scalable Authorisation Control architecture for the 21st century (EDSAC21, or just EDSAC) is then presented along with its four design layers. It builds on OASIS, adding support for the collaborative enforcement of distributed dynamic constraints, and incorporating publish/subscribe messaging to allow scalable and flexible deployment. The OASIS policy language is extended to support delegation, dynamic separation of duties, and obligation policies. An EDSAC prototype is examined. We show that our architecture is ideal for experiments performed into location-aware access control. We then demonstrate how event-based features specific to EDSAC facilitate integration of an ad hoc workflow monitor into an access control system. The EDSAC architecture is powerful, flexible and extensible. It is intended to have widespread applicability as the basis for designing next-generation security middleware and implementing distributed, dynamic privilege management.
Fusion,Cloning and Expression of the Gene Encoding OprF and OprH of Pseudomonas aeruginosa in E.coli (2004)

Objective To express tandemly the outer membrane protein OprF and OprH in Escherichia coli and obtain recombinant fused protein OprF/H for the further research of anti-PA vaccine.Methods The genomic DNA was extracted from Pseudomonas aeruginosa for the amplification of oprF and oprH with PCR.The PCR products were digested and ligated to form the oprF/H,the fused gene encoding the recombinant fused protein OprF/H. PCR was used to amplify the oprF/H gene.Then the PCR product was purified through gel electrophoresis and cloned for sequencing.The expression plasmid pGEX-F/H was constructed and then transformed to E.coli BL21.Results Recombinant expression plasmid expressed a corresponding fusion protein OprF/H after the induction of IPTG.Conclusion The construction and prokaryotic expression of fused outer membrane protein OprF/H were of successful.
Life-threatening adverse reactions after acupuncture? A systematic review (1997)

Department of Complementary Medicine, Postgraduate Medical School, University of Exeter, 25 Victoria Park Road, Exeter EX2 4NT, UK *Corresponding author. Tel.: +44 1392 430802; fax: +44 1392 424989; e-mail: [email protected] Received November 28, 1996; revised version received February 5, 1997; accepted February 5, 1997.
[POSTER] MR TV Mozaik: A New Mixed Reality Interactive TV Experience (2017)

Technicolor has been investigating how Mixed Reality technology could impact the future of home entertainment. We have designed and implemented a system to extend a standard TV experience with AR content, using a consumer tablet or a headset. A virtual TV mosaic is displayed around the TV screen and used as a GUI to control both TV and MR content. Using this interface, the user is able to switch TV content, display meta-data in AR (subtitles, text information or program guide), enhance TV content with interactive 3D objects blended in the environment, or play a game in interaction with the real world. The interactions between the real and the virtual worlds are handled thanks to a scene analysis pre-processing stage, which provides information about both the geometry and the lighting of the real environment. The real-virtual interactions strongly contribute to reinforcement of the immersion feeling. User feedback shows that the concept is very promising.
Diazines 13: Metalation without Ortho-Directing Group - Functionalization of Diazines via Direct Metalation (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDiazines 13: Metalation without Ortho-Directing Group - Functionalization of Diazines via Direct MetalationNelly Ple, Alain Turck, Karine Couture, and Guy QueguinerCite this: J. Org. Chem. 1995, 60, 12, 3781–3786Publication Date (Print):June 1, 1995Publication History Published online1 May 2002Published inissue 1 June 1995https://pubs.acs.org/doi/10.1021/jo00117a033https://doi.org/10.1021/jo00117a033research-articleACS PublicationsRequest reuse permissionsArticle Views1774Altmetric-Citations85LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts