gebhart/patrepeval huggingface dataset:
Oxygen torus in the deep inner magnetosphere and its contribution to recurrent process of O<sup>+</sup>-rich ring current formation (2011)

Using the magnetic field and plasma wave data obtained by the Combined Release and Radiation Effects Satellite (CRRES), we search for enhancements of O「+」 ion density in the deep inner magnetosphere known as "the oxygen torus". We examine 4 events on the dayside in which toroidal standing Alfvén waves appear clearly. From the frequency of the toroidal waves, the magnetospheric local mass density (ρ_L) is estimated by solving the MHD wave equation for realistic models of the magnetic field and the field line mass distribution. We also estimate the local electron number density (n_eL) from the plasma wave spectrograms by identifying narrow-band emission at the upper-hybrid resonance frequency. Assuming the quasi-neutral condition of plasma, we infer the local average ion mass (M_L) by ρ_L/n_eL. It is found that ML is approximately 3 amu in the plasma trough, while it shows an enhancement of >7 amu at L ∼ 4.5–6.5 that is close to the plasmapause at L ∼ 3.5–6.0. This indicates an existence of the oxygen torus in the vicinity of the plasmapause. The oxygen torus is found preferentially during the storm recovery phase. We interpret that these features of the oxygen torus (i.e., close relations with the plasmapause and the storm recovery phase) reflect its generation mechanism; that is, the ionospheric temperature is enhanced by heat conduction from high altitudes in the limited L range where the plasmasphere, because of its inflation during the recovery phase, encounters the ring current, and then the ionosphere has a larger scale height and supplies O[+] ions to the inner magnetosphere, resulting in the oxygen torus. We also discuss the contribution of the oxygen torus to the formation of the O[+]-rich ring current. It is proposed that the O[+]-rich ring current is formed in a recurrent process, in which the oxygen torus, the plasmasphere, and the ring current interact with each other.
Micro lens fabrication by means of femtosecond two photon photopolymerization (2006)

We report the fabrication of micro lens using an alternative annular scanning mode with continuous variable layer thickness by two-photon polymerization after multi-parameter optimization. Laser scanning mode and scanning pace parameter are optimized to achieve good appearance. As examples of the results, a 2 x 2 micro spherical lens array with diameter of 15 microm and a micro Fresnel lens with diameter of 17 microm are fabricated. Their optical performances are also tested. Compared to the conventional femtosecond two-photon fabrication, this work provides an alternative, effective and cheap processing method for the fabrication of micro optic device that requires arbitrary shape with high surface quality and small scale.
Insulin-Like Growth Factor-1, a Component of Serum that Enables Porcine Cumulus Cells to Expand in Response to Follicle-Stimulating Hormone in Vitro1 (1997)

The present study was aimed at determining whether insulin-like growth factor-1 (IGF-1) is a component of fetal bovine serum (FBS) that enables porcine cumulus cells to expand in response to FSH in vitro. Cumulus-oocyte complexes (COC) obtained from 4- to 6-mm follicles of prepubertal gilts were cultured at 39 degrees C for 24 h in media that contained human recombinant IGF-1 (50 ng/ml), FBS (15% v:v), or their combination, with or without FSH (1.5 microg/ml), and cumulus expansion was scored microscopically. Expansion was FSH dependent and was observed only when IGF-1, FBS, or both were present. The proportion of FSH-stimulated COC exhibiting full expansion in response to IGF-1 alone did not differ significantly (p > 0.05) from the proportion in those cultured with FBS or IGF-1+FBS (79 +/- 2.8% vs. 84 +/- 2.2% or 76 +/- 6.2%, respectively). In a concentration-response study, FSH-stimulated expansion was observed in a significant proportion of COC (32 +/- 2.8% vs. 0% control) at 1 ng/ml IGF-1, with the proportions increasing dose-dependently to maximal values between 10 and 75 ng/ml IGF-1, and decreasing at higher IGF-1 concentrations. Exposure of COC to an IGF-1 receptor (IGF-1R)-neutralizing antibody (Ab) for 90 min before addition of FSH and FBS dose-dependently inhibited cumulus expansion, with maximal inhibition at 10 microg/ml (1 +/- 1.0% vs. 68 +/- 1.1% control). In the absence of FBS or IGF-1, some COC had a tendency toward slight expansion when cultured with FSH, and the Ab completely inhibited that effect, suggesting that this may be due to endogenous IGF-1 production by the COC. The Ab effect was reversible and was eliminated by washing twice with fresh medium followed by culture for an additional 24 h in the presence of FSH and FBS. Expression of IGF-1R mRNA in the isolated oocyte and cumulus cells was determined by reverse tramscriptase polymerase chain reaction using sequence-specific primers. The IGF-1R message was detected in both the oocyte and cumulus cells. Collectively, these observations suggest that IGF-1 is a component of serum that enables cumulus cells to expand in response to FSH in vitro, and that the effect is receptor mediated. Since IGF-1 is present in the follicle in vivo, it may have a physiological role during gonadotropin-induced cumulus expansion.
HP-UX 11i Systems Administration Handbook and Toolkit, Second Edition (2003)

Your complete single source for HP-UX system administration!Now, there's a single source for all the information HP-UX administrators needto succeed! Marty Poniatowski has updated the world's #1 HP-UX systemadministration guide to cover all the latest HP-UX 11i enhancements, plus all theUNIX commands HP-UX sysadmins need. This edition also contains comprehensive newcoverage of the latest options and tools for HP-UX partitioning!HP-UX in depth... System boot: PDC, ISL, hpux, GSP, Secure Web Console, and Virtual Partition Booting Installing HP-UX, Software Distributor, and Operating Environments HP-UX kernel-including kernel update procedure Device files Users/groups, Ignite-UX backup/restore, and startup/shutdown scripts System Administration Manager (SAM) Logical Volume Manager with extensive examples-plus Veritas Volume Manager Performance management: iostat, vmstat, netstat, top, sar, and more Networking: Ethernet, TCP/IP, DNS, NFS, CIFS/9000, Samba, and more CDE and GNOMEUNIX commands and shells... File Types File Commands: cd, cp, file, ls, mv, mkdir, pwd, rm, rmdir, and more File Viewing: cat, head, tail, and more Advanced Commands: grep, sed, awk, find, cut, paste, split, sort, cmp, diff, comm, and more Bash, Korn, and C shells and shell programming Manual pages for many commonly used commands are included in the appendicesNew HP-UX partitioning coverage... vPars: preparation, creation, configuration, and commands nPartitions: creation, modification, cells, and commands HP Process Resource Manager (PRM) MC/ServiceGuard: background and examplesTear-out card includedSuperdome, rp8400, and rp7410 commandsCD-ROM includedIncludes trial versions of Hewlett-Packard's latest HP-UXperformance tools, plus Cheat Sheets for key sysadmintasks.
Plasmid-determined dehalogenation of haloacetates in Moraxella species. (1981)

A strain of Moraxella sp. capable of assimilating fluoroacetate (FA) as the sole source of carbon was isolated. It was resistant to mercuric chloride and antibiotics, such as penicillin G and kanamycin. Mercury reductase and haloacetate halidohydrolase were found in the cell-free extract of the organism. Two kinds of halidohydrolase were found on purification by DEAE-cellulose column chromatography; one was active for FA and chloroacetate (CA) (halidohydrolase 1), and the other was active for CA but not FA (halidohydrolase 2). Two types of cured strain were obtained by mitomycin C; type I lost halidohydrolase 2, whereas type II became sensitive to mercuric chloride and lost halidohydrolase 1 and 2. On electrophoresis of plasmid on agarose gel, a plasmid band was observed in a wild strain and a shorter band in type I. However, no band was observed in type II. Transferring of the plasmid by conjugation from a wild cell to a type II cell gave an exconjugant which possessed halidohydrolase 1 and 2 and became resistant to mercury. These results indicate that both halidohydrolase 1 and 2 and also mercury reductase are determined by the plasmid in the organism.
Expression of transforming growth factor-beta (TGF beta) isoforms and TGF beta type II receptor messenger ribonucleic acid and protein, and the effect of TGF beta s on endometrial stromal cell growth and protein degradation in vitro. (1994)

Reverse transcription-polymerase chain reaction analysis of total RNA and immunocytochemical observations revealed that human endometrial glandular epithelial and stromal cells in primary culture express messenger RNAs and proteins for transforming growth factor-beta 1 (TGF beta 1), TGF beta 2, and TGF beta 3 as well as TGF beta type II receptor. The epithelial and stromal cells synthesize and secrete into their culture-conditioned medium 2.6 +/- 0.3 and 1.4 +/- 0.2 ng TGF beta 1/10(6) cells, respectively; after transient acidification of the medium, the TGF beta 1 levels were 18.1 +/- 0.4 and 7.8 +/- 0.7 ng/10(6) cells. These cells also contain specific binding sites for [125I]TGF beta 1, indicated by light microscope autoradiography. TGF beta s at 0.01-10 ng/ml neither stimulated or inhibited subconfluent quiescent stromal cells under serum-free condition nor altered the mitogenic action of 10% fetal bovine serum. However, in the presence of 2% fetal bovine serum, which induced half-maximal stimulation of [3H]thymidine incorporation, TGF beta 1 and TGF beta 2 at 0.1-0.5 ng/ml and TGF beta 3 at 0.1-2.5 ng/ml significantly stimulated the rate of [3H]thymidine incorporation into quiescent stromal cells (P < 0.005); they were ineffective at higher concentrations. TGF beta s did not have any effect on cell proliferation, as determined by cell counting; however, at 0.1 ng/ml and higher concentrations, TGF beta s significantly reduced the metabolic activity of stromal cells, as determined by colorimetric 3-(4,5-dimethylthiazol-2-yl)2, 5-diphenyltetrazolium bromide assay (P < 0.05). The stimulatory and inhibitory actions of TGF beta s in both assays were reversible using 5-10 micrograms/ml TGF beta 1- and TGF beta 2- and 3-6 micrograms/ml TGF beta 3-specific neutralizing antibodies. TGF beta 1 at 1 ng/ml had no significant effect on long-lived protein degradation, assayed by incorporation of [14C]valine into newly synthesized protein by stromal cells, and was similar to the effect of epidermal growth factor or platelet-derived growth factor-BB (10 ng/ml). The data suggest that the TGF beta expression by various endometrial cell types in an autocrine/paracrine manner acts as a negative regulator essential for restraining endometrial growth and transition from proliferation to differentiation stages during the secretory phase after mitogenic stimulation during the proliferative phase of the menstrual cycle.
Religious Motifs and Biblical Allusions in the Works of Ana Maria Matute (1968)

ALTHOUGH ANA MARIA MATUTE varies her subject matter and experiments with style in her novels, she remains consistent in the expression of a uniquely personal world; she herself has stated that it is the duty of the novelist to express his own concept of the world through his characters and works.' Those who have followed this author's career are constantly delighted by her inexhaustible originality of form, but it has become apparent that she has chosen a limited number of symbolic situations and types as the best means of conveying her message. Among the basic themes of paramount importance in her novelistic production, Eugenio de Nora has noted (1) loneliness or lack of communication, (2) a mixture of love and hatred between brothers, lovers or friends, and (3) the necessity of escaping from life.2 I would add to these the inno-
Open Distributed Systems (1995)

Featuring approximately 60 illustrations, 30 equations and 100 references, this book is a comprehensive text for students, and a practical guide for engineers.
Characterization of the unusual antinociceptive profile of tramadol in mice (1993)

Abstract The present study characterized the antinociceptive effects of tramadol with emphasis on the site of action, the possible development of antinociceptive tolerance, and possible cross‐tolerance to morphine. Both tramadol and morphine produced antinociception as assessed in male, ICR mice using the warm water (55°C) tail‐flick test. Intrathecal (i.t.) tramadol produced an antinociceptive response, but with a shallow dose‐response curve (DRC), but i.c.v. tramadol was ineffective up to toxic doses (> 380 nmol). Simultaneous co‐administration of tramadol by the i.c.v. and i.t. routes in a 1:1 fixed dose‐ratio resulted in a synergistic interaction. Construction of a naloxone dose‐response curve against an A 90 dose of agonist yielded an AD 50 (and 95% C.L.) of 0.19 (0.14–0.33) and 0.55 (0.38–0.74) μmol/kg against morphine and tramadol, respectively; both agonists were completely antagonized by naloxone. In mice pretreated twice daily (8:00 a.m. and 5:00 p.m.) with s.c. morphine the DRC for morphine was displaced 16‐fold to the right, indicating significant development of antinociceptive tolerance. The same pretreatment resulted in only a 3‐fold right‐ward shift in the tramadol DRC. Chronic twice‐daily (8:00 a.m. and 5:00 p.m.) pretreatment with tramadol resulted in only an approximate 3‐ and 4‐fold rightward displacement in the tramadol and morphine DRCs, respectively. These results suggest that tramadol has an unusual antinociceptive mechanism which may reflect a primary site of action at spinal sites with a synergistic spinal/supraspinal interaction. Further, the lack of complete cross‐tolerance between tramadol and morphine supports the suggestion of a non‐opioid mechanism for this compound, whereas the complete antagonism by naloxone apparently reflects the opioid component of its mechanism in this test. Finally, the minimal development of tolerance to tramadol antinociception reinforces the view of a favorable tolerance‐dependence profile for this compound. © 1993 Wiley‐Liss, Inc.
Nial Alloys for Turbine Airfoils (1996)

NiAl alloys offer significant payoffs as structural materials in gas turbine applications due to high melting temperature, low density and high thermal conductivity.
Control of pulsatile secretion of gonadotrophin releasing hormone from hypothalamic explants (1993)

We have studied the secretion of gonadotrophin releasing hormone (GnRH) from hypothalamic explants of male rats at different ages in an attempt to delineate the neuroendocrine mechanism of the onset of puberty. In this paper, we review some of our recent studies and we provide evidence of a dual control played by receptors to neuroexcitatory amino acids. We showed previously that isolated explants of rat hypothalamus could secrete GnRH in a pulsatile manner. The onset of puberty was characterized by a 2-fold increase in frequency of GnRH secretory pulses. This reduction of the interval between GnRH pulses involved an inhibitory autofeedback effect of GnRH on the pulse generator which was shut off following a secretory episode. This period of refractoriness was longer before puberty than after the onset of puberty. Activation of receptors to neuroexcitatory amino acids (N-methyl-D-aspartate; NMDA-type) was involved in the mechanism of pulsatile GnRH secretion. Striking developmental changes in NMDA-receptor-mediated GnRH secretion were demonstrated with a maximal activity around the time of the onset of puberty. Similar changes occurred in orchidectomized animals, indicating that this maturational process was gonad-independent. While evidence accumulated that NMDA receptors were involved in a stimulatory control of GnRH secretion, we found that NMDA receptors mediated an inhibitory effect on GnRH secretion. This inhibitory effect was very potent in the immature hypothalamus and it showed a marked reduction in potency before onset of puberty.(ABSTRACT TRUNCATED AT 250 WORDS)
A Handbook of Fourier Theorems (1987)

This book is concerned with the well-established mathematical technique known as Fourier analysis (or alternatively as harmonic or spectral analysis). It is a handbook comprising a collection of the most important theorems in Fourier analysis, presented without proof in a form that is accurate but also accessible to a reader who is not a specialist mathematician. The technique of Fourier analysis has long been of fundamental importance in the physical sciences, engineering and applied mathematics, and is today of particular importance in communications theory and signal analysis. Existing books on the subject are either rigorous treatments, intended for mathematicians, or are intended for non-mathematicians, and avoid the finer points of the theory. This book bridges the gap between the two types. The text is self-contained in that it includes examples of the use of the various theorems, and any mathematical concepts not usually included in degree courses in physical sciences and engineering are explained. This handbook will be of value to postgraduates and research workers in the physical sciences and in engineering subjects, particularly communications and electronic engineering.
Large-Scale Characterization of Phosphoproteins in Gastric Cancer Cells. (2009)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTADDITION / CORRECTIONThis article has been corrected. View the notice.Large-Scale Characterization of Phosphoproteins in Gastric Cancer Cells.Guang-Rong Yan, Chuan-Le Xiao, Xing-Feng Yin, Hui-Hua Zhou, Zi-Lu Tan, and Qing-Yu He*Cite this: J. Proteome Res. 2011, 10, 10, 4883Publication Date (Web):August 27, 2009Publication History Published online27 August 2009Published inissue 7 October 2011https://pubs.acs.org/doi/10.1021/pr900385thttps://doi.org/10.1021/pr900385tcorrectionACS PublicationsCopyright © 2009 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views1127Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (619 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Laser capture sampling and analytical issues in proteomics (2007)

Proteomics holds the promise of evaluating global changes in protein expression and post-translational modification in response to environmental stimuli. However, difficulties in achieving cellular anatomic resolution and extracting specific types of proteins from cells have limited the efficacy of these techniques. Laser capture microdissection has provided a solution to the problem of anatomical resolution in tissues. New extraction methodologies have expanded the range of proteins identified in subsequent analyses. This review will examine the application of laser capture microdissection to proteomic tissue sampling, and subsequent extraction of these samples for differential expression analysis. Statistical and other quantitative issues important for the analysis of the highly complex datasets generated are also reviewed.
Buildup of image quality in view‐shared time‐resolved 3D CE‐MRA (2012)

Time-resolved three-dimensional contrast-enhanced MR angiography often relies on view sharing of peripheral k-space data to enable acquisition of angiograms with both high spatial resolution and a rapid frame rate. It is typically assumed that k-space will be fully sampled during passage of the contrast bolus arterial phase. However, this is not the case when view sharing is incomplete, for example, at the leading edge of an enhancing vessel or if acquisition time is limited as in fluoroscopic tracking for multistation bolus chase MR angiography. Incomplete view sharing will degrade image quality, for example, by reducing vessel signal and sharpness and increasing undersampling artifacts. In this work, the evolution of angiogram quality with view sharing is quantitatively assessed in phantom experiments and in vivo contrast-enhanced MR angiography calf studies. It is demonstrated that there are multiple sets of sequence parameters that can yield a target image update time, but the choice of parameters can profoundly affect how image quality evolves with view sharing. A fundamental tradeoff between vessel signal and sharpness and its relationship to the sequence temporal footprint is investigated and discussed.
Comparison of Structure‐ and Ligand‐Based Virtual Screening Protocols Considering Hit List Complementarity and Enrichment Factors (2009)

Structure- and ligand-based virtual-screening methods (docking, 2D- and 3D-similarity searching) were analysed for their effectiveness in virtual screening against four different targets: angiotensin-converting enzyme (ACE), cyclooxygenase 2 (COX-2), thrombin and human immunodeficiency virus 1 (HIV-1) protease. The relative performance of the tools was compared by examining their ability to recognise known active compounds from a set of actives and nonactives. Furthermore, we investigated whether the application of different virtual-screening methods in parallel provides complementary or redundant hit lists. Docking was performed with GOLD, Glide, FlexX and Surflex. The obtained docking poses were rescored by using nine different scoring functions in addition to the scoring functions implemented as objective functions in the docking algorithms. Ligand-based virtual screening was done with ROCS (3D-similarity searching), Feature Trees and Scitegic Functional Fingerprints (2D-similarity searching). The results show that structure- and ligand-based virtual-screening methods provide comparable enrichments in detecting active compounds. Interestingly, the hit lists that are obtained from different virtual-screening methods are generally highly complementary. These results suggest that a parallel application of different structure- and ligand-based virtual-screening methods increases the chance of identifying more (and more diverse) active compounds from a virtual-screening campaign.
First Experimental Demonstration of Secure NFV Orchestration over an SDN-Controlled Optical Network with Time-Shared Quantum Key Distribution Resources (2016)

We demonstrate, for the first time, a secure optical network architecture that combines NFV orchestration and SDN control with quantum key distribution (QKD) technology. A novel time-shared QKD network design is presented as a cost-effective solution for practical networks.
Copolymerization of CO<sub>2</sub> and Epoxides Catalyzed by Metal Salen Complexes (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.