gebhart/patrepeval huggingface dataset:
On the need for system-level support for ad hoc and sensor networks (2002)

Ad hoc and sensor networks are an important, emerging niche that is poorly supported by existing operating systems. In this paper, we argue that network-wide energy management is a primary concern in ad hoc networks, and that this functionality is best provided by a systems layer. We are currently designing and implementing a distributed, power-aware, adaptive operating system, called MagnetOS, specifically targeting ad hoc and sensor networks. MagnetOS provides a single system image of a unified Java virtual machine across the nodes that comprise an ad hoc network. By automatically and transparently partitioning applications into components and dynamically placing these components on nodes within the ad hoc network, our system reduces energy consumption, avoids hotspots and increases system longevity. We show that a systems approach to automatic object placement in an ad hoc network can increase system longevity by a factor of four to five.
Indirect deep structured learning for 3D human body shape and pose prediction (2017)

In this paper we present a novel method for 3D human body shape and pose prediction. Our work is motivated by the need to reduce our reliance on costly-to-obtain ground truth labels. To achieve this, we propose training an encoder-decoder network using a two step procedure as follows. During the first step, a decoder is trained to predict a body silhouette using SMPL (a statistical body shape model) parameters as an input. During the second step, the whole network is trained on real image and corresponding silhouette pairs while the decoder is kept fixed. Such a procedure allows for an indirect learning of body shape and pose parameters from real images without requiring any ground truth parameter data. Our key contributions include: (a) a novel encoder-decoder architecture for 3D body shape and pose prediction, (b) corresponding training procedure as well as (c) quantitative and qualitative analysis of the proposed method on artificial and real image datasets.
A salute to the American Institute of Electrical Engineers (1959)

It will be a notable event not only in the development of engineering but in our national history when the American Institute of Electrical Engineers celebrates its Seventy-fifth Anniversary.
3D head tracking using non-linear optimization (2003)

Accurate and reliable tracking of the 3D position of human heads is a continuing research problem in computer vision. This paper addresses the speciﬁc problem of model-based tracking with a generic deformable 3D head model. Following the work of Vetter and Blanz, a collection of head models is obtained from a 3D scanner, registered and parameterized to give a generic head model which is linearly parameterized by a small number of parameters. This is the 3D analogue of Cootes and Taylor’s active appearance models. We cast tracking as a parameter estimation problem, and note that many existing solutions to the problem—such as CONDENSATION and Kalman ﬁltering—are analogous to nonlinear optimization strategies in numerical analysis. We show how careful analysis of the error function, parameterization of the model pose parameters, and choice of optimizer allows us to robustly track 3D head pose in digital video camera footage of quickly moving heads.
BRM sequence generators based on the field GF(2/sup n/) for DSP implementations (2002)

This paper describes the extended LFSR (ELFSR) and the extended BRM (EBRM) based on the field GF(2/sup n/). We claim that those presented generators are efficient and suitable for S/W implementation. We also claim that the EBRM can be used as a good non-linear logic for stream cipher systems.
Pro-inflammatory cytokine release by peripheral blood mononuclear cells from patients with advanced pancreatic cancer: Relationship to acute phase response and survival (2009)

The acute phase protein response (APPR) and peripheral blood mononuclear cell-derived inflammatory cytokine production was assessed in patients with advanced pancreatic cancer and age-matched healthy volunteers. We examined the relationship between the APPR, cytokine production and survival in these patients. Forty-two patients with pancreatic cancer cachexia and twelve age-matched healthy controls were recruited. The nutritional status, Karnofsky performance score, C reactive protein (CRP), serum interleukin-6, and in vitro monocyte interleukin-1 and interleukin-6 production were measured. The dates of death of the pancreatic cancer patients were subsequently obtained and appropriate patient variables at baseline were entered into a Cox's proportional hazards model. The cancer patients had significantly lower: body mass index, Karnofsky performance score, serum albumin and elevated CRP and stimulated interleukin-6 production. Both univariate and multivariate analysis demonstrated a strong association between tumour stage, CRP, stimulated interleukin-6 production and survival. Monocytes in cachectic pancreatic cancer patients are primed to produce high levels of interleukin-6 when stimulated. Overproduction of interleukin-6 has a negative impact on survival. Decreased survival is associated with an elevated APPR. While the elevated APPR is probably related to locally produced interleukin-6 in the liver, it seems possible that locally and systemically produced interleukin-6 influences survival.
Polypeptoids from <i>N</i>-Substituted Glycine <i>N</i>-Carboxyanhydrides: Hydrophilic, Hydrophobic, and Amphiphilic Polymers with Poisson Distribution (2011)

Preparation of defined and functional polymers has been one of the hottest topics in polymer science and drug delivery in the recent decade. Also, research on (bio)degradable polymers gains more and more interest, in particular at the interface of these two disciplines. However, in the majority of cases, combination of definition, functionality and degradability, is problematic. Here we present the preparation and characterization (MALDI–ToF MS, NMR, GPC) of nonionic hydrophilic, hydrophobic, and amphiphilic N-substituted polyglycines (polypeptoids), which are expected to be main-chain degradable and are able to disperse a hydrophobic model compound in aqueous media. Polymerization kinetics suggest that the polymerization is well controlled with strictly linear pseudo first-order kinetic plots to high monomer consumption. Moreover, molar mass distributions of products are Poisson-type and molar mass can be controlled by the monomer to initiator ratio. The presented polymer platform is nonionic, backbone degradable, and synthetically highly flexible and may therefore be valuable for a broad range of applications, in particular as a biomaterial.
Synthesis of New Trans Double-Bond Sphingolipid Analogues:  Δ<sup>4,6</sup> and Δ<sup>6</sup> Ceramides (2002)

Unsaturation was introduced at Delta(4,6) and Delta(6) of the sphingoid chain of naturally occurring ceramide 1 via a beta-keto sulfoxide (12) and sulfone (18) derived from N-Boc-L-serine methyl ester acetonide (9), affording two novel ceramide analogues, (2S,3R)-2-octanoylamidooctadeca-(4E,6E)-diene-1,3-diol (2) and (2S,3R)-2-octanoylamidooctadec-(6E)-ene-1,3-diol (3). After C-alkylation of 12 with (E)-1-bromo-2-tetradecene (8), a trans double bond was installed by elimination of PhS(O)H, providing conjugated dienone oxazolidine 13. Reaction of 18 with 8, followed by desulfonation (Al(Hg)), afforded keto-oxazolidine 20, which bears a (E)-Delta(6) double bond. The syntheses of analogues 2 and 3 from ketones 13 and 20, respectively, were completed by the following sequence of reactions: diastereoselective reduction (NaBH(4)/CeCl(3) or DIBAL-H), hydrolysis of the oxazolidine ring, liberation of the amino group, and installation of the N-amide group.
Synthesis and reactivity of ruthenium tridentate bis-phosphinite ligand complexes (2013)

The tridentate ligands E(CH2CH2OPiPr2)2 (E = NH 1, E = S 2) were employed in the synthesis of a number of ruthenium complexes. Reaction of these ligands with (Ph3P)3RuCl2 afforded the dimers [Ru(HN(CH2CH2OPiPr2)2)Cl(μ-Cl)]2 (3) and [(Ru(E(CH2CH2OPiPr2)2))2(μ-Cl)3][X] (E = NH, X = PF64, E = S, X = Cl 5), respectively. Using (Ph3P)3RuHCl in reactions with 1 gave Ru(NH(CH2CH2OPiPr2)2)(PPh3)HCl (6) while addition of pyridine and 2, gave Ru(S(CH2CH2OPiPr2)2)(py)HCl (7). Treatment of 6 or 7 with NaBPh4 resulted in the formation of the η(6)-arene complexes RuH(E(CH2CH2OPiPr2)2)2(η(6)-C6H5BPh3) (E = NH 8, E = S 9) while reactions with K[B(C6F5)4] gave the salts [RuH(E(CH2CH2OPiPr2)2)(L)][B(C6F5)4] (E = NH, L = PPh310, E = S, L = py 12). Compounds 6 and 7 react with CO giving RuH(HN(CH2CH2OPiPr2)2)(CO)Cl (15) and [RuH(S(CH2CH2OPiPr2)2(py)(CO)]Cl (16) respectively, while reaction of 6, 10 or 12 with dihydrogen gave RuH(HN(CH2CH2OPiPr2)2)(H2)Cl (18) and RuH(E(CH2CH2OPiPr2)2)(L)(H2)][B(C6F5)4] (E = NH, L = PPh319, E = S, L = py 20). The complexes 4-12, 15 and 16 are shown to catalyze the dehydrogenation of HMe2NBH3.
<title>Parallel architecture dedicated to image component labeling in O(n Log n): FPGA implementation</title> (1996)

Connected component labelling is sa fundamental task in intermediate level vision. Current research points to parallel architecture as an excellent solution in response to this problem. In order to exploit a global approach while optimizing the electronic structure and minimizing data propagation, a parallel architecture dedicated to image component labeling is envisages. For an n by n image, the optimized architecture merely requires n/2-1 PE's and n<SUP>2</SUP>/4 CAM (content addressable memory) modules through a 4 pixels grouping technique. The global communication is reconfigurable and ensured in O(log n) units of propagation time by a tree structure of switches. Moreover, a PE permits sequential processing in its memories array, perfectly adapted to labeling from any interlaced-mode video signal. In this mode, the architecture permits labeling in one scan image while simultaneously loading the image. The proposed algorithm, based on a divide-and-conquer technique, leads to a complexity of O(n log n) with a small constant multiplicative factor. We discuss the simulation results, the possibility of FPGA implementation and of development of this architecture.
Interruption of the Progression of Heart Failure: Are ACE Inhibitors the Solution? (1996)

Our options for the medical management of heart failure are aimed at preventing the development of the condition, relieving symptoms, modifying the underlying pathophysiology, and delaying or preventing disease progression. The principal symptoms of heart failure are edema, dyspnea and fatigue. Diuretics are effective in relieving edema, and dyspnea resulting from pulmonary edema. Once pulmonary edema has been treated relatively few agents are effective against residual exercise-induced dyspnea, possibly because of the numerous possible causes of this symptom. Angiotensin-converting enzyme (ACE) inhibitors have, however, been shown to improve dyspnoea by mechanisms that are not related to hemodynamic actions. These agents also improve skeletal muscle blood flow and function, thereby relieving fatigue in heart failure patients. Treatment strategies aimed at modifying the underlying pathophysiology or preventing disease progression have, with the exception of the ACE inhibitors, met with limited success. Large-scale trials have shown, however, that ACE inhibitors improve survival in patients with moderate or severe heart failure, and prevent the development of heart failure in asymptomatic patients. These agents, therefore, represent an important advance in the management of heart failure, and it is anticipated that new insights into their optimal use will follow as the mechanisms by which they exert their beneficial effects become clear.
ATP/ADP binding sites are present in the sulfonylurea binding protein associated with brain ATP-sensitive potassium channels (1992)

Covalent labeling of nucleotide binding sites of the purified sulfonylurea receptor has been carried out with alpha-32P-labeled oxidized ATP. The main part of 32P incorporation is in the 145-kDa glycoprotein that has been previously shown to be the sulfonylurea binding protein (Bernardi et al., 1988). ATP and ADP protect against this covalent labeling with K0.5 values of 100 microM and 500 microM, respectively. Non-hydrolyzable analogs of ATP also inhibit 32P incorporation. Interactions between nucleotide binding sites and sulfonylurea binding sites have then been observed. AMP-PNP, a nonhydrolyzable analog of ATP, produces a small inhibition of [3H]glibenclamide binding (20-25%) which was not influenced by Mg2+. Conversely, ADP, which also produced a small inhibition (20%) in the absence of Mg2+, produced a large inhibition (approximately 80%) in the presence of Mg2+. This inhibitory effect of the ADP-Mg2+ complex was observed with a K0.5 value of 100 +/- 40 microM. All the results taken together indicate that ATP and ADP-Mg2+ binding sites that control the activity of KATP channels are both present on the same subunit that bears the receptors for antidiabetic sulfonylureas.
Short and long term prognosis in perinatal asphyxia: An update (2016)

Interruption of blood flow and gas exchange to the fetus in the perinatal period, known as perinatal asphyxia, can, if significant, trigger a cascade of neuronal injury, leading on to neonatal encephalopathy (NE) and resultant long-term damage. While the majority of infants who are exposed to perinatal hypoxia-ischaemia will recover quickly and go on to have a completely normal survival, a proportion will suffer from an evolving clinical encephalopathy termed hypoxic-ischaemic encephalopathy (HIE) or NE if the diagnosis is unclear. Resultant complications of HIE/NE are wide-ranging and may affect the motor, sensory, cognitive and behavioural outcome of the child. The advent of therapeutic hypothermia as a neuroprotective treatment for those with moderate and severe encephalopathy has improved prognosis. Outcome prediction in these infants has changed, but is more important than ever, as hypothermia is a time sensitive intervention, with a very narrow therapeutic window. To identify those who will benefit from current and emerging neuroprotective therapies we must be able to establish the severity of their injury soon after birth. Currently available indicators such as blood biochemistry, clinical examination and electrophysiology are limited. Emerging biological and physiological markers have the potential to improve our ability to select those infants who will benefit most from intervention. Biomarkers identified from work in proteomics, metabolomics and transcriptomics as well as physiological markers such as heart rate variability, EEG analysis and radiological imaging when combined with neuroprotective measures have the potential to improve outcome in HIE/NE. The aim of this review is to give an overview of the literature in regards to short and long-term outcome following perinatal asphyxia, and to discuss the prediction of this outcome in the early hours after birth when intervention is most crucial; looking at both currently available tools and introducing novel markers.
Electro-optically switchable spatial-mode entangled photon pairs using a modified Mach–Zehnder interferometer (2012)

In this Letter, we propose and analyze a switchable integrated optical waveguide device employing a modified Mach-Zehnder interferometer, capable of generating nondegenerate, maximally spatial-mode entangled photon pairs. Using an integrated electro-optic phase modulator, we show the possibility of on-demand switching of spatial-mode entangled state from a Φ+ to a Ψ+ state and vice versa. Such a versatile device with the potential of easy manipulation of the "spatial-mode" degree of freedom, should be very interesting in realizing integrated optical chips for quantum information processing.
Writing IIS applications in dyalog APL (2002)

article Share on Writing IIS applications in dyalog APL Author: Peter Donnelly Dyadic Systems Limited, Old Basing, Basingstoke, Hampshire, United Kingdom Dyadic Systems Limited, Old Basing, Basingstoke, Hampshire, United KingdomView Profile Authors Info & Claims ACM SIGAPL APL Quote QuadVolume 33Issue 1September 2002 pp 13–17https://doi.org/10.1145/637350.637353Online:01 September 2002Publication History 0citation209DownloadsMetricsTotal Citations0Total Downloads209Last 12 Months0Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
End-of-dose Wearing Off in Parkinson Disease (2006)

We have previously reported that the use of a 32-symptom Wearing-off Questionnaire (WOQ-32) identified wearing off more frequently than a clinician's evaluation or the complications subscale of the Unified Parkinson Disease Rating Scale (UPDRS). However, this prototype tool was not designed for clinical practice and required simplification for daily use. Although wearing off is a commonly understood concept among neurologists caring for Parkinson disease patients, there are a number of definitions in the literature. For the purpose of this study and to include both motor and nonmotor parkinsonian symptoms, wearing off was defined as a generally predictable recurrence of motor and nonmotor symptoms that precedes scheduled doses of anti-parkinsonian medication and usually improves after those doses. Using this definition, retrospective analysis and expert opinion were used to identify the 9 most predictive and relevant of the symptoms previously identified as part of the WOQ-32. The resulting 9-symptom questionnaire (WOQ-9) identified 158 (95.8%) of the 165 subjects captured by the 32-Symptom Wearing-off Questionnaire as having wearing off, excluding 7 subjects reporting only balance difficulty (n = 3), numbness (n = 2), difficulty standing (n = 1), and abdominal discomfort (n = 1). Subjects reporting wearing off with the WOQ-9 were significantly younger, had been longer diagnosed with Parkinson disease, experienced a longer duration of levodopa therapy, exhibited a higher UPDRS total score, had higher levodopa equivalent dosages, and increased dyskinesia compared with patients not identified as wearing off with the WOQ-9. No statistical differences were noted with respect to sex, UPDRS subsection scores, Schwab & England Scale, or Hoehn & Yahr Scale.
Prevalence of human T-cell leukemia/lymphoma virus (HTLV) type II infection among high-risk individuals: type-specific identification of HTLVs by polymerase chain reaction (1989)

The extent of human T-cell leukemia/lymphoma virus type II (HTLV-II) infection and its rate of spread have been difficult to determine owing to the serological cross-reactivity between HTLV-I and HTLV-II. The present study overcame this problem by directly detecting type-specific proviral sequences by means of the polymerase chain reaction (PCR) and liquid hybridization. Screening was performed on a cohort of primarily white intravenous drug abusers (IVDAs), and individuals of other behaviorally defined risk groups from the New York City area. Eleven percent (19 of 169) of the individuals in these high-risk groups were determined by PCR to have HTLV-II proviral infections. One of these patients displayed an exfoliative erythrodermatitis. Thirteen of the 19 subjects were positive in an HTLV-II enzyme-linked immunosorbent assay (ELISA). The remaining six individuals, although negative in the HTLV- II ELISA, were confirmed as HTLV-II positive by analyzing their DNA with a second HTLV-II-specific primer detector system. Four additional individuals were reactive in the HTLV-II ELISA but were PCR-negative for HTLV-II. PCR analysis for HTLV-I revealed that all four were positive for that virus. Thirty-seven percent (seven of 19) of the HTLV- II PCR-positive subjects were also PCR-positive for HTLV-I, and 84% (16 of 19) of the HTLV-II positive individuals were infected with human immunodeficiency virus (HIV-1). Six individuals were triply infected with HTLV-I, HTLV-II, and HIV-1.
Reduction in Oocyte Number Following Prenatal Exposure to a Diet High in Galactose (1981)

When pregnant rats were fed a 50 percent galactose diet there was a striking reduction in oocyte number in the offspring. The most prominent effects were noted after exposure to galactose during the premeiotic stages of oogenesis. Prenatal exposure to galactose or its metabolites may contribute to the premature ovarian failure characteristic of human galactosemia.
Spatial Variation in Sympathetic Influences on the Vasculature of the Synovium and Medial Collateral Ligament of the Rabbit Knee Joint (1997)

1. Laser Doppler perfusion imaging was used to assess the role of the sympathetic nervous system in the control of blood flow to the medial collateral ligament and capsule (synovium and overlying fibrous tissues) of the rabbit knee joint. 2. Electrical stimulation of the saphenous nerve (width 1 ms; amplitude 20V; 1-30 Hz) produced a frequency-dependent vasoconstriction of knee joint vasculature. The response was maximal at 30 Hz and gave the greatest fall in perfusion at the femoral insertion of the ligament (by 33.8 +/- 7.4%, mean +/- S.E.M.; n = 5-6) and the smallest decrease at the tibial insertion of the ligament (by 10.6 +/- 2.9%). 3. Topical application of phentolamine (10(-6) mol) had no significant effect on basal knee joint blood flow. However, it abolished the nerve-mediated constrictor responses in all regions of the medial collateral ligament and synovium at all frequencies. 4. Topical administration of adrenaline (10(-14) to 10(-7) mol) caused a dose-dependent decrease in knee joint blood flow with the highest dose producing > 75% reduction in perfusion at all areas. 5. There was no evidence of a reactive hyperaemia in the 5 min following a 5 min period of femoral artery occlusion. Artificial manipulation of arterial blood pressure by intravenous infusion or withdrawal of blood caused a proportional change in ligament and synovial blood flow. These observations may indicate a lack of autoregulation in the joint and its exclusion from baroreflex modulation. 6. These results suggest a potential role for the sympathetic nervous system in the control of knee joint blood flow. Neuromodulation of ligament perfusion appears to predominate at the femoral insertion and this could prove to have functional significance.
Tissue ablation with radiofrequency using multiprobe arrays. (1995)

Multiprobe radiofrequency arrays permit the destruction of more tissue in a single treatment session than is possible with multiple individual probes operating alone. Probes spaced 1.5 cm or less apart act synergistically, producing a total volume of coagulated tissue that is greater than when the individual probes are operated sequentially.