gebhart/patrepeval huggingface dataset:
Adaptive Deep Learning-Based Point Cloud Geometry Coding (2020)

Point clouds are a very rich 3D visual representation model, which has become increasingly appealing for multimedia applications with immersion, interaction and realism requirements. Due to different acquisition and creation conditions as well as target applications, point clouds' characteristics may be very diverse, notably on their density. While geographical information systems or autonomous driving applications may use rather sparse point clouds, cultural heritage or virtual reality applications typically use denser point clouds to more accurately represent objects and people. Naturally, to offer immersion and realism, point clouds need a rather large number of points, thus asking for the development of efficient coding solutions. The use of deep learning models for coding purposes has recently gained relevance, with latest developments in image coding achieving state-of-the-art performance, thus making natural the adoption of this technology also for point cloud coding. This paper presents a novel deep learning-based solution for point cloud geometry coding which is able to efficiently adapt to the content's characteristics. The proposed coding solution divides the point cloud into 3D blocks and selects the most suitable available deep learning coding model to code each block, thus maximizing the compression performance. In comparison to the state-of-the-art MPEG G-PCC Trisoup standard, the proposed coding solution offers average quality gains up to 4.9 and 5.7 dB for PSNR D1 and PSNR D2, respectively.
Separation of Duty in Role Based Access (2007)

In today’s business world, many organizations use Information Systems to many their sensitive and business critical information. The need to protect such a key component of the organization cannot be over emphasized. Access control has been found to be one of the effective ways of insuring that only authorized users have access to the information resources to perform their job function. Role Based Access Control has been found to be the access control mechanism that fits naturally with the organizational structure of businesses. Separation of duties is a security principle that has been used extensively to prevent conflict of interest, fraud and error control in organizations. In this thesis, we identify the various forms of separation of duties in role based access control systems. We also do a case study of the role based access control system in the banking application of a financial institution.
Brain arousal and information theory: neural and genetic mechanisms (2006)

Preface and Dedication 1. Toward a Universal Theory of Brain Arousal What Is to Be Explained? Ethology and the Mechanisms of Arousal Operational Definition of Arousal A Quantitative Approach to Physical Measurement of Generalized Arousal The Neurobiology of Arousal Constitutes an Interesting Application of Information Theory Claims for This Chapter and Introduction to Chapters Following 2. Anatomy Is Not Destiny, but a Little Neuroanatomy Helps Multiplicity and Redundancy of Ascending Arousal Pathways Prevent Failure Primitive Master in the Brainstem Provide a Neuroanatomic Core that Theoretically Matches the Behavioral Data Long-Distance Lines Tuning Local Modules Summary and Hypothetical Implications for Human Behavior 3. Arousal Is Signaled by Electrical Discharges in a System of Nerve Cells Traveling Up the Brainstem Special Cases: Olfaction and Vision Informational Content Governs Amplitude of Response in Neurons Related to Arousal Cerebral Cortex, the EEG Electrical Activity in Three Arousal-Related Biological Systems 4. Autonomic Nervous System Changes Supporting Arousal the Unity of the Body Patterns of Autonomic Responses Reformulations A High Information System Shows Coordination sans Correlation Supporting Hormone-Dependent Behaviors Summary 5. Genes Whose Neurochemical Products Support Arousal Genes Associated with Classical Systems Genes Newly Recognized Concepts and Questions Summary 6. Heightened States of Arousal: Sex Compared to Fear Sex Behavior's CNS Mechanisms Require Arousal Generalized Arousal Affects Specific Arousals and Vice Versa Contrast Sex and Fear Applicability of Information Theory Libido and Stress in Humans Summary 7. Major Systems Questions about Brain Arousal Networks What Are Universal Operating Features of Arousal Systems? How Do We Meet the Requirement for Rapid Changes of CNS State? Sensitivity and Alacrity of Response, Yet Stability? How? Does Automata Theory Apply? Questions in the Time Domain Questions about Spatial Properties Thermodynamics, Information Theory, and Questions for the CNS How Does a Sine Wave Impact a Sawtooth? Unity from Diversity? 8. Summary and Practical Importance: From Biological Mechanisms to Health Applications Main Points Applications to Human Conditions Works Cited Acknowledgments Index
Scientific inventory planning in materials management. (1989)

This is all just one example of how computer and appropriate analytical software routines can improve the fiscal and physical efficiency of the hospital materials management department. Together, they can provide logical, unemotional guidelines for purchase quantities, reorder points and safety stocks. Once a computer based materials management tool is in place and the materials manager has appropriate software at his or her disposal, a whole array of other possibilities can open up. For example, with appropriate analytical software and about six months of data, materials managers can estimate the performance of a current inventory system, comparing it to the expected results of upgrading current software. In effect, you can predetermine the cost-effectiveness of embedding economic order quantities, reorder points and service level policy routines before committing to such a course. Another valuable tool for materials management is "cost/use variance" software, which can pinpoint quickly and by line item whether inventory costs are rising due to higher vendor costs or to expanded use of products, and what percent each represents. A natural extension of this is an ABC analysis to identify groups of line items deserving more or less intense management. Continuous vendor performance tracking is another candidate for analytical software. The cost consequences of partial, late or missed deliveries can be severe, and delivery documentation becomes critical if the hospital has a performance liability agreement with the vendor. Other analytical software may permit dramatic improvement in storeroom labor efficiency through logical stock location schemes. In short, the basic formulas for scientific inventory management are only the beginning of a complex materials management story.
An innovative distributed instrument for WirelessHART testing (2009)

In the last few years solutions adopted in industrial communication have been deeply changed thanks to the adoption of technologies borrowed from completely different areas. In particular, the advent of hybrid wired/wireless networks promises to greatly improve efficiency and scalability. However, their success will depend on the availability of standard solutions, that ensure multivendor compatibility. Recently, the WirelessHART specifications have been released, making it the only available standard for wireless networking in the industrial field. In this paper, authors present an innovative distributed instrument that will make easier the debug and the development of WirelessHART devices and networks.
Damage arrest design approach using stitched composites (2011)

Abstract Although the deployment of carbon fibre structural components has enjoyed wide success on smaller aircraft, their acceptance on larger transport airframes is less sanguine – especially in the case of primary structure applications where the increasing out of plane loads found on the larger airframes have exposed the weak interlaminar properties of the layered material system. This has led to an overreliance on mechanical attachments to suppress these through thickness failures, which ultimately degrades structural performance and increases manufacturing costs. Until these resin dominated failure modes can be dealt with more effectively, without adversely affecting the in plane properties of the laminate, the true weight-savings potential afforded by carbon fibre material systems will be difficult to attain. This paper describes how researchers at NASA-LaRC and The Boeing Company are working to develop a next generation stitched composite design solution that addresses the fundamental challenges in achieving improved structural performance and reduced fabrication costs for large carbon fibre airframe structures.
Real-time stereo rectification using compressed look-up table with variable breakpoint indexing (2016)

Real-time rectification of stereo cameras is critical for stereoscopy in 3D vision and display. FPGA-based rectification has been suffering from the usage of large internal memory inside of the FPGA. The paper proposes a real-time stereo rectification approach using variable breakpoint indexing for enhanced compressed look-up table algorithm (E-CLUTR) in order to reduce the size of memory inside FPGA and to get a wider field-of-view (FoV) using high-distortion lenses. The proposed approach was successfully simulated using Altera ModelSim 10.4b. It is shown that the memory usage is reduced by 58∼65% compared with previous approaches and it supports real-time rectification of stereo 1920×1080 high-definition video data in 50 fps for a high-distortion lens with 110 degrees FoV.
Towards efficient proofs of retrievability (2012)

Proofs of Retrievability (POR) is a cryptographic formulation for remotely auditing the integrity of files stored in the cloud, without keeping a copy of the original files in local storage. In a POR scheme, a user Alice backups her data file together with some authentication data to a potentially dishonest cloud storage server Bob. Later, Alice can periodically and remotely verify the integrity of her data file using the authentication data, without retrieving back the data file. Besides security, performances in communication, storage overhead and computation are major considerations. Shacham and Waters (Asiacrypt '08) gave a fast scheme with O(sλ) bits communication cost and a factor of 1/s file size expansion where λ is the security parameter. In this paper, we incorporate a recent construction of constant size polynomial commitment scheme (Kate, Zaverucha and Goldberg, Asiacrypt '10) into Shacham and Waters scheme. The resulting scheme requires O(λ) communication bits (particularly, 920 bits if a 160 bits elliptic curve group is used or 3512 bits if a 1024 bits modulo group is used) per verification and a factor of 1/s file size expansion. Experiment results show that our proposed scheme is indeed efficient and practical. Our security proof is based on Strong Diffie-Hellman Assumption.
STUDIES ON VALIDAMYCINS, NEW ANTIBIOTICS. IV (1971)

Newantibiotics named validamycins A and B, active against the sheath blight of rice plants, were isolated from the culture nitrate of Streptomyces hygroscopicus var. limoneus. Validamycins A and B are water-soluble, glucosecontaining basic antibiotics, and with molecular formulae of C20H3337NO1314 and C20H3337NO1415, respectively.
Derivatives of Guanosine Triphosphate with Ribose 2′‐Hydroxyl Substituents (1976)

This report describes the preparation of four methylated and phosphorylated derivatives of GTP, 2'-O-methylguanosine 5'-triphosphate (PPP-Me2' Guo), and guanosine 2'-monophosphate 5'-triphosphate (PPP-Guo-2'P), 3'-O-methylguanosine 5'-triphosphate (PPP-Me3'Guo), and guanosine 3'-monophosphate 5'-triphosphate (PPP-Guo-3'P). These compounds were compared to GTP in their ability to support reactions catalyzed by Escherichia coli initiation factor 2(IF-2), elongation factor Tu (EF-Tu), and elongation factor G )EF-G). As with previously studied GTP analogues, the nucleotide specificities of IF-2-dependent N-formylmethionylpuromycin formation and EF-Tu-dependent Ac-Phe2-tRNA formation were similar. There was little difference between the reactions supported by GTP, PPP-Me2' Guo, PPP-Me3' Guo, and PPP-Guo-3'P, but PPP-Guo-2'P was a poor substrate with both enzymes. A spectrum of activity was observed in EF-G-dependent formation of N-acetylphenylalanylphenylalanylpuromycin. While PPP-Me2' Guo was almost as effective as GTP in supporting translocation, PPP-Guo-2'P was a very poor substrate, having even less activity than guanosine 3'-diphosphate 5'-triphosphate. Intermediate activities were observed with PPP-Me3' Guo and PPP-Guo-3'P, the former nucleotide being more active than the latter.
The Wrb antigen, a receptor for <i>Plasmodium falciparum</i> malaria, is located on a helical region of the major membrane sialoglycoprotein of human red blood cells (1983)

1. Immunoprecipitation of periodate/NaB3H4-labelled human erythrocytes using anti-Wrightb (Wrb) monoclonal antibodies showed that these antibodies specifically react with the major erythrocyte sialoglycoprotein alpha (glycophorin A). 2. Similar experiments on erythrocytes from the only known individual lacking the Wrb antigen but with otherwise normal sialoglycoproteins did not result in the immunoprecipitation of any sialoglycoprotein. 3. We suggest that the Wrb antigen is located on an alpha-helical region between residues 55 and 70 of sialoglycoprotein alpha.
Expression and Stereochemical and Isotope Effect Studies of Active 4-Oxalocrotonate Decarboxylase (2000)

4-Oxalocrotonate decarboxylase (4-OD) and vinylpyruvate hydratase (VPH) from <i>Pseudomonas\nputida mt-2 </i>form a complex that converts 2-oxo-3-hexenedioate to 2-oxo-4-hydroxypentanoate in the\ncatechol meta fission pathway. To facilitate mechanistic and structural studies of the complex, the two\nenzymes have been coexpressed and the complex has been purified to homogeneity. In addition, Glu-106, a potential catalytic residue in VPH, has been changed to glutamine, and the resulting E106QVPH\nmutant has been coexpressed with 4-OD and purified to homogeneity. The 4-OD/E106QVPH complex\nretains full decarboxylase activity, with comparable kinetic parameters to those observed for 4-OD in the\nwild-type complex, but is devoid of any detectable hydratase activity. Decarboxylation of (5<i>S</i>)-2-oxo-3-[5-D]hexenedioate by either the 4-OD/VPH complex or the mutant complex generates 2-hydroxy-2,4<i>E</i>-[5-D]pentadienoate in D<sub>2</sub>O. Ketonization of 2-hydroxy-2,4-pentadienoate by the wild-type complex is\nhighly stereoselective and results in the formation of 2-oxo-(3<i>S</i>)-[3-D]-4-pentenoate, while the mutant\ncomplex generates a racemic mixture. These results indicate that 2-hydroxy-2,4-pentadienoate is the product\nof 4-OD and that 2-oxo-4-pentenoate results from a VPH-catalyzed process. On this basis, the previously\nproposed hypothesis for the conversion of 2-oxo-3-hexenedioate to 2-oxo-4-hydroxypentanoate has been\nrevised [Lian, H., and Whitman, C. P. (1994) <i>J. Am. Chem. Soc. 116</i>, 10403−10411]. Finally, the observed\n<sup>13</sup>C kinetic isotope effect on the decarboxylation of 2-oxo-3-hexenedioate by the 4-OD/VPH complex\nsuggests that the decarboxylation step is nearly rate-limiting. Because the value is not sensitive to either\nmagnesium or manganese, it is likely that the transition state for carbon−carbon bond cleavage is late\nand that the metal positions the substrate and polarizes the carbonyl group, analogous to its role in\noxalacetate decarboxylase.
Minimum cycle time location of a task in the workspace of a robot arm (2003)

A novel approach to optimal placement of a prescribed task in the workspace of a robotic manipulator is presented. The cycle time for a specified set of minimum-time straight-line movements is used as the optimality criterion. These movements are point-to-point, and the arm starts from standstill at the initial point and stops at the final point. Local velocity patterns for minimum-time straight-line movements in the regions of interest are obtained. This information is used to choose a good initial location for the task. A step-and-test method is then used to find the minimum-cycle-time location for the considered task. Results of application of this method to a manipulator with two revolute joints are presented. The results indicate that proper positioning of the task in the workspace can considerably reduce the cycle time and therefore increase productivity.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Loss of a Consensus Splice Signal in a Mutant Immunoglobulin Gene Eliminates the CH<sub>1</sub> Domain Exon from the mRNA (1984)

A series of mouse myeloma mutants, derived from a cell line of the murine MPC-11 tumor (gamma 2b, kappa), resemble human heavy-chain disease in their loss of an internal domain (exon). In these mutants, most of the gamma 2b CH1 exon was present in the nuclear RNA but was removed during splicing to form the mature cytoplasmic RNA. Amino acid sequence studies of one mutant (10.1) are consistent with the loss of the complete CH1 domain. A second mutant cell line (I17) derived from 10.1 and containing the same CH1 alteration was shown by S1 nuclease protection experiments to have an additional mRNA deletion spanning the CH2-CH3 domain boundary. This second deletion was shown to result from a genomic alteration that provided a marker for the isolation of the expressed H-chain allele. To determine the basis of the CH1 splicing defect, the 117 genome-expressed gamma 2b constant region DNA was cloned. Sequence studies showed a deletion of 99 nucleotides around the 3' end of the CH1 domain, which removed the splice site and flanking DNA, apparently causing the aberrant splicing of the RNA transcript. The sequence deleted in the mutant is flanked by short repeats of the octameric sequence CCAGCCAG in the wild-type gene. In the mutant, one copy of the repeat, in addition to the sequences between the repeats, has been lost.
DBMiner: a system for mining knowledge in large relational databases (1996)

A data mining system, DBMiner, has been developed for interactive mining of multiple-level knowledge in large relational databases. The system implements a wide spectrum of data mining functions, including generalization, characterization, association, classification, and prediction. By incorporating several interesting data mining techniques, including attributeoriented induction, statistical analysis, progressive deepening for mining multiple-level knowledge, and meta-rule guided mining, the system provides a userfriendly, interactive data mining environment with good performance. Introduction With the upsurge of research and development activities on knowledge discovery in databases (PiatetskyShapiro &amp; Frawley 1991; Fayyad et al. 1996), a data mining system, DBMiner, has been developed based on our studies of data mining techniques, and our experience in the development of an early system prototype, DBLearn. The system integrates data mining techniques with database technologies, ...
Parallelization of Particle Swarm Optimization and Its Implementation on Scalable Multi-core Architecture (2009)

The Particle Swarm Optimization (PSO) is a stochastic, population-based algorithm for search and optimization from a multidimensional space. Many engineering design problems in real life have complicated optimization functions, which require massive computational power, to solve in reasonable time when implemented sequentially. Thus, scalable parallel implementations are required to speed up these algorithms, and reduce the over-all design process time. In this paper, we present a model for parallelization of PSO algorithm, and its implementation on Cell Broadband Engine architecture.
Ribosomopathies: human disorders of ribosome dysfunction (2010)

Ribosomopathies compose a collection of disorders in which genetic abnormalities cause impaired ribosome biogenesis and function, resulting in specific clinical phenotypes. Congenital mutations in RPS19 and other genes encoding ribosomal proteins cause Diamond-Blackfan anemia, a disorder characterized by hypoplastic, macrocytic anemia. Mutations in other genes required for normal ribosome biogenesis have been implicated in other rare congenital syndromes, Schwachman-Diamond syndrome, dyskeratosis congenita, cartilage hair hypoplasia, and Treacher Collins syndrome. In addition, the 5q- syndrome, a subtype of myelodysplastic syndrome, is caused by a somatically acquired deletion of chromosome 5q, which leads to haploinsufficiency of the ribosomal protein RPS14 and an erythroid phenotype highly similar to Diamond-Blackfan anemia. Acquired abnormalities in ribosome function have been implicated more broadly in human malignancies. The p53 pathway provides a surveillance mechanism for protein translation as well as genome integrity and is activated by defects in ribosome biogenesis; this pathway appears to be a critical mediator of many of the clinical features of ribosomopathies. Elucidation of the mechanisms whereby selective abnormalities in ribosome biogenesis cause specific clinical syndromes will hopefully lead to novel therapeutic strategies for these diseases.
VE-Cadherin Disassembly and Cell Contractility in the Endothelium are Necessary for Barrier Disruption Induced by Tumor Cells (2017)

During metastasis, breakdown of the endothelial barrier is critical for tumor cell extravasation through blood vessel walls and is mediated by a combination of tumor secreted soluble factors and receptor-ligand interactions. However, a complete mechanism governing tumor cell transendothelial migration remains unclear. Here, we investigate the roles of tumor-associated signals in regulating endothelial cell contractility and adherens junction disassembly leading to endothelial barrier breakdown. We show that Src mediates VE-cadherin disassembly in response to metastatic melanoma cells. Through the use of pharmacological inhibitors of cytoskeletal contractility we find that endothelial cell contractility is responsive to interactions with metastatic cancer cells and that reducing endothelial cell contractility abrogates migration of melanoma cells across endothelial monolayers. Furthermore, we find that a combination of tumor secreted soluble factors and receptor-ligand interactions mediate activation of Src within endothelial cells that is necessary for phosphorylation of VE-cadherin and for breakdown of the endothelial barrier. Together, these results provide insight into how tumor cell signals act in concert to modulate cytoskeletal contractility and adherens junctions disassembly during extravasation and may aid in identification of therapeutic targets to block metastasis.