gebhart/patrepeval huggingface dataset:
Dégradation catalytique de carbamates herbicides deposés sur bentonites homoïoniques. IV. Cas du carbetamide (1986)

Résumé: Summary: Zusammenfassung En phase sèche à 20° C, le carbétamide peut se dégrader lentement sur divers supports argileux homoïoniques (Bentonite Prolabo, Montmorillonite K 10; Cu ++ , Zn ++ , Fe +++ ). Le Cuivre présente la meilleure activité. Un processus de dégradation suivant deux voies parallèles a été mis en évidence au cours de la première étape. La sélectivité observée est influencée par la méthode d'imprégnation, la nature du support et du métal. A température supérieure (80° C), on observe sur gel de silice et Montmorillonite K 10 un processus plus complet de dégradation qui permet de confirmer la formation d'isocyanate intermédiaire lors de l'hydrolyse de la fonction carbamate du substrat. Surface catalysed degradation of carbamate herbicides on bentonites. IV. Carbetamide The chemical degradation of carbetamide on various homoionic clays (Bentonite Prolabo, Montmorillonite K 10:Cu ++ , Zn ++ , Fe +++ ) (was investigated at room temperature. The kinetics of the reaction was generally slow; however, copper was the most active metal. The first stage of the chemical process included two ways of degradation. The selectivity of the conversion was influenced by the impregnation technique, clay type and exchange metal. At a higher temperature (80° C) on silica gel and montmorillonite K 10, the whole process of degradation was observed which indicated that isocyanate is involved as an intermediate in the carbamate hydrolysis function. Katalytischer Abbau von Carbamaten an Bentaniten. IV. Carbetamid Der chemische Abbau von Carbetamid an verschiedenen homoionischen Tonmineralen (Bentonit Prolabo, Montmorillonit K 10; Cu 2+ , Fe 3+ ) wurde bei Zimmertemperatur untersucht. Die Reaktion war allgemein langsam, aber Kupfer war am wirksamsten. Die erste Stufe des Abbaus besteht aus zwei Wegen, worüber die Art der Imprägnierung, das Tonmineral und die ausgetauschten Metalle entscheiden. Bei höherer Temperatur (80° C) konnte an Silicagel und Montmorillonit K 10 der gesamte Abbauprozess beobachtet werden, wobei sich zeigte, dass Isocyanat als Zwischenprodukt der Hydrolyse von Carbamat auftritt.
FRONT PAGES (2020)

1. Cover2. Editorial Team3. from the editor4. Table of Contents)
Applying semantic web and user behavior analysis to enforce the intrusion detection system (2009)

The Web Service has been extended to the back-end database. In this paper, we propose a novel method of user behavior analysis in semantic network. We use the weight value to analyze and record user behavior and then check user behavior record with the signatures which are generated by the Intrusion Detection System (IDS). If a user record matches with signatures, the system will pass the record to the Analysis Console for Intrusion Database (ACID) to do more the further processing and then response to user. The ACID does not only help the system administrator to maintain and protect the web service in order to prevent the intruders' attacking but also show the security information. In the current Internet, it is a very complex and insecure environment. Everything can be happened in this environment. In our solution, it can not only successfully solve the Cross-Site Scripting (XSS) attack and SQL Injection attack but also understand user behavior. In the future work, we can use user behavior information to design securer Web service.
RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF ATORVASTATIN CALCIUM, LOSARTAN POTASSIUM, ATENOLOL, AND ASPIRIN FROM TABLET DOSAGE FORM AND PLASMA (2012)

A rapid, simple, sensitive, and selective chromatographic method has been developed for the simultaneous estimation of atorvastatin calcium, losartan potassium, atenolol, and aspirin in marketed formulation. The separation was carried out on a KYA TECH HiQ Sil C18HS (250 × 4.6 mm i.d., 5 µm particle size) column using a mobile phase of acetonitrile: 0.02 M potassium dihydrogen phosphate buffer (pH 3.4) (70:30% v/v). The chromatographic analysis has been carried out using flow rate of 1 mL/min and detection at 236 nm. The proposed method was applied for analysis of ATN, ASP, LOS and ATO from plasma. ATO showed a linear response in the concentration range of 4–24 µg/mL, LOS and ATN showed a linear response in the concentration range of 20–120 µg/mL and ASP showed a linear response in the concentration range of 30–180 µg/mL in tablet formulation analysis. ATO, LOS, ASP, and ATN showed a linear response in the concentration range of 25–150, 50–300, 100–600, and 50–300 ng/mL in plasma analysis, respectively. The proposed methods for analysis of the four drugs from marketed formulation and plasma have been validated as per ICH and USFDA guidelines, respectively. Thus, proposed methods have their applications in field of bioequivalence and pharmacokinetic studies.
Univariate time series prediction of solar power using a hybrid wavelet-ARMA-NARX prediction method (2016)

This paper proposes a new hybrid method for super short-term solar power prediction. Solar output power usually has a complex, nonstationary, and nonlinear characteristic due to intermittent and time varying behavior of solar radiance. In addition, solar power dynamics is fast and is inertia less. An accurate super short-time prediction is required to compensate for the fluctuations and reduce the impact of solar power penetration on the power system. The objective is to predict one step-ahead solar power generation based only on historical solar power time series data. The proposed method incorporates discrete wavelet transform (DWT), Auto-Regressive Moving Average (ARMA) models, and Recurrent Neural Networks (RNN), while the RNN architecture is based on Nonlinear Auto-Regressive models with eXogenous inputs (NARX). The wavelet transform is utilized to decompose the solar power time series into a set of richer-behaved forming series for prediction. ARMA model is employed as a linear predictor while NARX is used as a nonlinear pattern recognition tool to estimate and compensate the error of wavelet-ARMA prediction. The proposed method is applied to the data captured from UCLA solar PV panels and the results are compared with some of the common and most recent solar power prediction methods. The results validate the effectiveness of the proposed approach and show a considerable improvement in the prediction precision.
Recognition of Named-Event Passages in News Articles (2013)

We extend the concept of Named Entities to Named Events - commonly occurring events such as battles and earthquakes. We propose a method for finding specific passages in news articles that contain information about such events and report our preliminary evaluation results. Collecting "Gold Standard" data presents many problems, both practical and conceptual. We present a method for obtaining such data using the Amazon Mechanical Turk service.
Smallpox as a Biological Weapon (2003)

Once believed eradicated, smallpox has returned as a potential threat. Healthcare providers, as the first line of defense, must be proactive in maintaining current resources and offering input into the preparation for, diagnosis, and management of smallpox should an outbreak occur. The critical care nurse is integral in all aspects regarding smallpox and bioterrorism.
Highly Electroconductive Metal–Organic Framework: Tunable by Metal Ion Sorption Quantity (2019)

This study has developed a simple and innovative approach to design a metal-organic framework (MOF) with tunable conductivity. The in situ amine functionalized TMU-60 [Zn(OBA)(L*)·DMF] has the potential of converting to a conductor due to the selective and fast sorption of cadmium ion. In order to precisely monitor the cadmium penetration to the framework pores, in addition to full kinetic and thermodynamic studies of sorption, the time-dependent effects of Cd(II) penetration to MOF pores was taken by fluorescence and electrochemical methods. The results obviously prove that the conductivity of the structure can be adjusted by changing the Cd exposure time and the quantity of ion sorption. The presence of cadmium ions can enhance the ability of the framework to pass electrons through its constituents. Even though the porosity of the structure remains to a certain extent, the achieved tunable and highly stable electrical conductivity is provided by sorption of metal ions. More importantly, the conductivity has been improved from 53 × 10<sup>-6</sup> to 1.8 × 10<sup>-2</sup> S·cm<sup>-1</sup> for TMU-60 and TMU-60-Cd compressed pellet (room temperature), respectively. The mechanism of charge transport through the pellet is proposed to be a hopping mechanism between metal nodes and localized Cd(II) after sorption, which is supported by chronoamperometry measurement. A fit of the time-dependent data to the Cottrell equation gave a charge-transport diffusion coefficient of 1.6 × 10<sup>-10</sup> cm<sup>2</sup>/s throughout the structure. This novel approach not only enhances the conductivity of the MOF but also allows adjusting the conductivity according to the desired applications.
Methamphetamine Causes Mitrochondrial Oxidative Damage in Human T Lymphocytes Leading to Functional Impairment (2010)

Methamphetamine (METH) abuse is known to be associated with an inordinate rate of infections. Although many studies have described the association of METH exposure and immunosuppression, so far the underlying mechanism still remains elusive. In this study, we present evidence that METH exposure resulted in mitochondrial oxidative damage and caused dysfunction of primary human T cells. METH treatment of T lymphocytes led to a rise in intracellular calcium levels that enhanced the generation of reactive oxygen species. TCR-CD28 linked calcium mobilization and subsequent uptake by mitochondria in METH-treated T cells correlated with an increase in mitochondrion-derived superoxide. Exposure to METH-induced mitochondrial dysfunction in the form of marked decrease in mitochondrial membrane potential, increased mitochondrial mass, enhanced protein nitrosylation and diminished protein levels of complexes I, III, and IV of the electron transport chain. These changes paralleled reduced IL-2 secretion and T cell proliferative responses after TCR-CD28 stimulation indicating impaired T cell function. Furthermore, antioxidants attenuated METH-induced mitochondrial damage by preserving the protein levels of mitochondrial complexes I, III, and IV. Altogether, our data indicate that METH can cause T cell dysfunction via induction of oxidative stress and mitochondrial injury as underlying mechanism of immune impairment secondary to METH abuse.
Visual Progressive Coding (1999)

The embedded coder has an attractive feature that the coding bitstream can be truncated later at any point and still decoded a perceptible image. It is common in conventional coding to improve the subjective quality of the coded image through adjusting the quantization step size inversely proportional to a set of visual weights. However, such scheme will not be effective in the embedded coder as different viewing condition may be called for at different stages of embedding. In this paper, we propose the visual progressive coding (VIP), which uses the visual weights to determine the order of embedding, rather than to requantize the transform coefficients. VIP can change the weights halfway through redefining the order of embedding according to the active weights. With such “reordering by weight ” strategy, it is feasible to adjust the visual weights flexibly during the embedding process, and improve the subjective appearance of the image over the entire bit rate.
Direct observation of oxygen movement during resistance switching in NiO/Pt film (2008)

We demonstrate that both a low resistance state and a high resistance state can be written by bipolar voltage application in a local region of NiO/Pt films by using conducting atomic force microscopy. To investigate how oxygen played a role in the resistance switching phenomenon, a local writing process in O18 tracer gas atmosphere was carried out and the composition change was examined by time-of-flight secondary ion mass spectroscopy. As a result, it was revealed that oxygen moves to the anode side, and the composition of the NiO surface might change thereby causing the change in resistance.
On the Structure and Interpretation of the Infrared Absorption Spectra of Crystals (1935)

An experimental and theoretical investigation of the absorption spectrum of MgO in the near infrared is reported. Part A is devoted to the experimental results, which were obtained by use of a rocksalt spectrometer. They show that the fundamental absorption is accompanied by a great deal of secondary structure. In Part B an interpretation of the results of A is undertaken on the basis of a quantum-mechanical treatment of anharmonic potential forces. On this basis, it is shown that a cubic crystal of the MgO type should not possess but a single near infrared absorption as previous calculations had indicated, but should possess an extremely complicated secondary structure. In Part C the possibilities of obtaining a quantitative correlation between experiment and theory are discussed and it is concluded that the former must be made the object of additional refinements.
Selectivity and minimal androgenicity of norgestimate in monophasic and triphasic oral contraceptives (1992)

The contraceptive progestin norgestimate (NGM) has a high affinity for uterine progestin receptors and a lack of affinity for androgen receptors similar to that of natural progesterone. NGM's selectivity results in excellent efficacy, cycle control, and minimal androgenicity when it is combined with ethinyl estradiol (EE). Clinical studies of a monophasic regimen of NGM/EE indicate a positive impact on lipid metabolism, revealing an increase in serum levels of high-density lipoprotein cholesterol with a concomitant and significant decrease in the low-density lipoprotein/high-density lipoprotein cholesterol ratio. Little impact on carbohydrate metabolism was noted. Serum levels of sex hormone binding globulin, an indicator of androgen-estrogen balance, also increased significantly with NGM/EE in accordance with its low androgenic activity. A significant between-regimen difference in SHBG was seen in a comparison study of NGM/EE and LNG/EE triphasic formulations (a mean rise of 68.6% with NGM/EE vs a decrease of 6.1% with LNG/EE). NGM's lack of estrogenicity was evidenced by unchanged prolactin levels and absence of effect on the coagulation system. In a large study of the monophasic formulation in 59,701 women, some improvement in acne was reported as well as minimal weight gain. An overview of clinical data is provided from United States and European trials as well as some preclinical data relevant to NGM's selectivity.
Realization Of A Spatial Augmented Reality System - A Digital Whiteboard Using a Kinect Sensor and a PC Projector (2013)

Recent rapid development of cost-effective, accurate digital imaging sensors, high-speed computational hardware, and tractable design software has given rise to the growing field of augmented reality in the computer vision realm. The system design of a 'Digital Whiteboard' system is presented with the intention of realizing a practical, cost-effective and publicly available spatial augmented reality system.\n\nA Microsoft Kinect sensor and a PC projector coupled with a desktop computer form a type of spatial augmented reality system that creates a projection based graphical user interface that can turn any wall or planar surface into a 'Digital Whiteboard'. The system supports two kinds of user inputs consisting of depth and infra-red information. An infra-red collimated light source, like that of a laser pointer pen, serves as a stylus for user input. The user can point and shine the infra-red stylus on the selected planar region and the reflection of the infra-red light source is registered by the system using the infra-red camera of the Kinect. Using the geometric transformation between the Kinect and the projector, obtained with system calibration, the projector displays contours corresponding to the movement of the stylus on the 'Digital Whiteboard' region, according to a smooth curve fitting algorithm. The described projector-based spatial augmented reality system provides new unique possibilities for user interaction with digital content.
<title>Developments and applications of confocal theta microscopy</title> (1999)

Confocal theta microscopy improves the resolution of confocal laser scanning microscopes by solving the problem of the inferior axial resolution instrumentally. The specimens are observed at an angle theta relative to the illumination axis (ideally 90 degrees). The resulting observation volume, defined by the product of illumination and detection point spread functions (PSFs), is reduced by 2.5 and has an isotropic shape. Single-Lens Theta Microscopy (SLTM) is a technical variation of confocal theta microscopy. It is designed to be easily adapted to any common confocal laser scanning microscope. It is based on the use of a mirror unit between the microscope objective lens and its focal plane. This mirror unit deflects the incoming and outcoming light in such a way, that the detection axis is perpendicular to the illumination axis. With SLTM different kinds of other microscopical techniques (such as 4Pi microscopy) are possible. The quantitative evaluation of physical test systems underline the feasibility of SLTM and prove the excellent resolution. The extensions of the experimentally determined point spread functions fit well with the predicted theoretical values. The technique was applied to the investigation of GFP labelled organelles in HeLa cells as well as for the analysis of embryos.
PSORT-B: improving protein subcellular localization prediction for Gram-negative bacteria (2003)

Automated prediction of bacterial protein subcellular localization is an important tool for genome annotation and drug discovery. PSORT has been one of the most widely used computational methods for such bacterial protein analysis; however, it has not been updated since it was introduced in 1991. In addition, neither PSORT nor any of the other computational methods available make predictions for all five of the localization sites characteristic of Gram-negative bacteria. Here we present PSORT-B, an updated version of PSORT for Gram-negative bacteria, which is available as a web-based application at http://www.psort.org. PSORT-B examines a given protein sequence for amino acid composition, similarity to proteins of known localization, presence of a signal peptide, transmembrane alpha-helices and motifs corresponding to specific localizations. A probabilistic method integrates these analyses, returning a list of five possible localization sites with associated probability scores. PSORT-B, designed to favor high precision (specificity) over high recall (sensitivity), attained an overall precision of 97% and recall of 75% in 5-fold cross-validation tests, using a dataset we developed of 1443 proteins of experimentally known localization. This dataset, the largest of its kind, is freely available, along with the PSORT-B source code (under GNU General Public License).
Computer Correction of Camera Nonidealities in Gamma Ray Imaging (1982)

Digital methods to correct for imperfections in gamma ray cameras are reviewed. The two principal problems currently addressed are nonlinearities in the analog position signals, and variations with position in the magnitude of the energy signal. As an example of real-time processing to correct for these imperfections, the operation of the Medical Data Systems image preprocessor is outlined. A new technique is described that leads to the establishment of an "adaptive" energy window to further improve image uniformity.
The Cancer Genome Anatomy Project: new resources for reading the molecular signatures of cancer (2001)

The Cancer Genome Anatomy Project (CGAP) has built informational, technological, and physical resources to interface genomics with basic and clinical cancer research. The CGAP web site (http://cgap.nci.nih.gov) provides informatics tools for in silico analysis of the CGAP datasets as well as information for accessing each of the CGAP resources. Published in 2001 by John Wiley & Sons, Ltd.
Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood (2010)

A robust PD biomarker assay suitable for clinical use has been developed in human whole blood. The successful adaptation of the assay to cynomolgus monkeys has enabled the demonstration of Ab-01 activity both in vitro and in vivo in monkey, thus validating the use of this species in safety studies and establishing proof-of-concept for using this PD assay system to aid in dose selection in clinical studies.
Prospects for treating osteoarthritis: enzyme–protein interactions regulating matrix metalloproteinase activity (2012)

Primary osteoarthritis (OA) is a musculoskeletal disorder of unknown etiology. OA is characterized by an imbalance between anabolism and catabolism in, and altered homeostasis of articular cartilage. Matrix metalloproteinases (MMPs) and a disintegrin and metalloproteinase with thrombospondin motif are upregulated in OA joints. Extracellular matrix (ECM) proteins are critical for resistance to compressive forces and for maintaining the tensile properties of the tissue. Tissue inhibitor of metalloproteinases (TIMPs) is the endogenous inhibitor of MMPs, but in OA, TIMPs do not effectively neutralize MMP activity. Upregulation of MMP gene expression occurs in OA in a milieu of proinflammatory cytokines such as interleukin (IL)-1, IL-6 and tumor necrosis factor α. Presently, the medical therapy of OA includes mainly nonsteroidal anti-inflammatory drugs and corticosteroids which dampen pain and inflammation but appear to have little effect on restoring joint function. Experimental interventions to restore the imbalance between anabolism and catabolism include small molecule inhibitors of MMP subtypes or inhibitors of the interaction between IL-1 and its receptor. Although these agents have some positive effects on reducing MMP subtype activity they have little efficacy at the clinical level. MMP-9 is one MMP subtype implicated in the degradation of articular cartilage ECM proteins. MMP-9 was found in OA synovial fluid as a complex with neutrophil gelatinase-associated lipocalin (NGAL) which protected MMP-9 from autodegradation. Suppressing NGAL synthesis or promoting NGAL degradation may result in reducing the activity of MMP-9. We also propose initiating a search for enzyme-protein interactions to dampen other MMP subtype activity which could suppress ECM protein breakdown.
Dynamic portfolio management under competing representations (2005)

Purpose To solve the multi‐period portfolio management problem under transactions costs. Design/methodology/approach We apply a recently designed super genetic hybrid algorithm (SuperGHA) – an integrated optimisation system for simultaneous parametric search and non‐linear optimisation – to a recursive portfolio management decision support system (SHAREX). The parametric search machine is implemented as a genetic superstructure, producing tentative parameter vectors that control the ultimate optimisation process. Findings SHAREX seems to outperform the buy and hold‐strategy on the Finnish stock market. The potential of a technical portfolio system is best exploitable under favorable market conditions. Originality/value A number of robust engines for matrix algebra, mathematical programming and numerical calculus have been integrated with SuperGHA. The engines expand its scope as a general‐purpose algorithm for mathematical programming.