gebhart/patrepeval huggingface dataset:
Mood Predicts Response to Placebo CPAP (2012)

Study Objectives. Continuous positive airway pressure (CPAP) therapy is efficacious for treating obstructive sleep apnea (OSA), but recent studies with placebo CPAP (CPAP administered at subtherapeutic pressure) have revealed nonspecific (or placebo) responses to CPAP treatment. This study examined baseline psychological factors associated with beneficial effects from placebo CPAP treatment. Participants. Twenty-five participants were studied with polysomnography at baseline and after treatment with placebo CPAP. Design. Participants were randomized to either CPAP treatment or placebo CPAP. Baseline mood was assessed with the Profile of Mood States (POMS). Total mood disturbance (POMS-Total) was obtained by summing the six POMS subscale scores, with Vigor weighted negatively. The dependent variable was changed in apnea-hypopnea index (ΔAHI), calculated by subtracting pre- from post-CPAP AHI. Negative values implied improvement. Hierarchical regression analysis was performed, with pre-CPAP AHI added as a covariate to control for baseline OSA severity. Results. Baseline emotional distress predicted the drop in AHI in response to placebo CPAP. Highly distressed patients showed greater placebo response, with a 34% drop (i.e., improvement) in AHI. Conclusion. These findings underscore the importance of placebo-controlled studies of CPAP treatment. Whereas such trials are routinely included in drug trials, this paper argues for their importance even in mechanical-oriented sleep interventions.
Zinc gluconate and the common cold. Review of randomized controlled trials. (1998)

Evidence supports use of zinc gluconate lozenges for reducing the symptoms and duration of the common cold, but the side effects, bad taste, and therapeutic protocol might limit patient compliance.
Complementary use of simulation and experimental methods in deriving Pcd/h for target components (2014)

The V/L code simulation method has been employed to develop Pcd/h of an electric relay which was used as a target in an experimental study for achieving its Pcd/h. Three different simulations have been conducted to reproduce kill probabilities of the relay resulted from the experiment. While vulnerability simulations produced much lower kill probabilities than the experiment result, a lethality simulation correctly reproduced it. It is discussed that if the lethality simulation setup correctly re‐enacted the experiment, the experiment result cannot be interpreted as correct Pcd/h of the relay. Rather the correct one should be the result of the vulnerability simulation performed with the same setup as the lethality simulation. Finally, this paper concludes with stress on the need and importance of complementary use of the simulation and experiment methods in deriving component Pcd/h.
A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity (2003)

A low molecular weight nonpeptide compound, KRH-1636, efficiently blocked replication of various T cell line-tropic (X4) HIV type 1 (HIV-1) in MT-4 cells and peripheral blood mononuclear cells through the inhibition of viral entry and membrane fusion via the CXC chemokine receptor (CXCR)4 coreceptor but not via CC chemokine receptor 5. It also inhibited binding of the CXC chemokine, stromal cell-derived factor 1alpha, to CXCR4 specifically and subsequent signal transduction. KRH-1636 prevented monoclonal antibodies from binding to CXCR4 without down-modulation of the coreceptor. The inhibitory effect against X4 viral replication by KRH-1636 was clearly reproduced in the human peripheral blood lymphocytesevere combined immunodeficiency mouse system. Furthermore, this compound was absorbed into the blood after intraduodenal administration as judged by anti-HIV-1 activity and liquid chromatography MS in the plasma. Thus, KRH-1636 seems to be a promising agent for the treatment of HIV-1 infection.
Selective molecularly imprinted stationary phases for Bisphenol A analysis prepared by modified precipitation polymerization (2009)

Bisphenol A (BPA)-imprinted polymeric microspheres were synthesized by modified precipitation polymerization (MPP) method. Influences of cross-linker, monomer, porogen volume, and agitation on polymerization were investigated. Proper amount of cross-linker ethyleneglycol-dimethacrylate (EGDMA) was critical to achieve narrowly dispersed microspheres. For template BPA, monomer 4-vinylpyridine (4-VP) was better than MAA to get the best imprinted effects. The optimum template/monomer ratio was 1:6. Increasing porogen volume increased size dispersity and decreased binding characters. Agitation increased coagulation and resulted in irregular particles. Microspheres with the best binding characters were used as selective stationary phase of chromatographic column to detect BPA in milk, pig urine, and chicken meat. Under optimal chromatographic conditions, the calibration graph was linear with R2 = 0.9994 in the range of 3-50 micromol/L. The LOD and LOQ were 1 and 3 micromol/L, respectively. When large amounts (20 mL or 20 g) of samples were analyzed, the recoveries ranged from 70.2 to 87.3% with RSD less than 4.85% in all samples spiked with 0.05-0.2 micromol/L BPA. The intra-day and inter-day RSD were less than 1.83 and 3.96%, respectively. Microspheres prepared by MPP are successfully used in molecularly imprinted polymer (MIP)-based analytical column to detect trace BPA in different biologic samples with acceptable accuracy and repeatability.
Investigation of some covalent and noncovalent complexes by matrix-assisted laser desorption/ionization time-of-flight and electrospray mass spectrometry (1999)

Covalent and noncovalent complexes involving bovine superoxide dismutase, bovine alpha-lactalbumin and two variants, A and B, of bovine beta-lactoglobulin have been examined by delayed extraction matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) and electrospray mass spectrometry. Covalent complexation with acrylamide was obtained through the interaction of these proteins with acrylamide monomers while treatment with peroxynitrite yielded complexes with NO2. Some of the complexation sites with acrylamide were reliably identified by performing tryptic digestion followed by MALDI-TOF measurements in the reflection mode. These data demonstrate that the presence of free cysteine in the investigated sequences is not a precondition for the observation of Cys-acrylamide complexes. Although the bulk of the present work is dedicated to the characterization of Cys-acrylamide adducts, the preliminary data on noncovalent complexes between two of those proteins and 8-anilinonaphthalene-1-sulfonic acid (ANS) were easily observed under electrospray conditions, while under MALDI-TOF conditions only the complex with beta-lactoglobulin B was clearly evident. The presented data demonstrate the advantage of the parallel use of both ionization techniques for this type of investigation.
Mutations in the human factor XII gene. (1997)

The factor XII gene from 31 unrelated factor XII-deficient patients from Germany, Switzerland, and Austria was screened for mutations at the genomic level. Several novel mutations were detected and their absence in a control group of 74 healthy unrelated individuals was checked. Most changes are in the serine protease domain affecting the catalytic triad His-393-Asp-442-Ser-544; two missense mutations, R398Q (arginine 398 to glutamine; gene bank accession no. U71276) and L395M (leucine 395 to methionine; gene bank accession no. U71277), are close to the active site histidine at position 393. Another mutation detected in a cross-reacting material (CRM)-positive female with a history of three abortions affects the active site aspartic acid by changing it to asparagine (D442N; gene bank accession no. U71275). The novel mutation G570R (glycine 570 to arginine; gene bank accession no. U71274) giving rise to a CRM-positive phenotype is located next to Cys571, which forms a vital disulfide bridge. Two mutations are causing reading frame shifts: one single basepair deletion in exon 12 [exon 12: 10590(DelC); gene bank accession no. U71278] and one acceptor splice site mutation [exon 14: 11397(G --> A); gene bank accession no. L43615]. The putative regulatory mutation exon 1:-8 (g --> c) in the upstream region of the gene is associated with an aberrant Taq I restriction site allele in intron B of the gene (gene bank accession no. X80393).
The implications of global economic transformations for Australia (2011)

This speech was delivered on 19 September 2011 to the Australian Industry Group Annual National Forum.
Ring-opening copolymerization (ROCOP): synthesis and properties of polyesters and polycarbonates (2015)

Controlled routes to prepare polyesters and polycarbonates are of interest due to the widespread application of these materials and the opportunities provided to prepare new copolymers. Furthermore, ring-opening copolymerization may enable new poly(ester-carbonate) materials to be prepared which are inaccessible using alternative polymerizations. This review highlights recent advances in the ring-opening copolymerization catalysis, using epoxides coupled with anhydrides or CO2, to produce polyesters and polycarbonates. In particular, the structures and performances of various homogeneous catalysts are presented for the epoxide-anhydride copolymerization. The properties of the resultant polyesters and polycarbonates are presented and future opportunities highlighted for developments of both the materials and catalysts.
A mercury(<scp>ii</scp>) ion sensor device based on an organic field effect transistor with an extended-gate modified by dipicolylamine (2015)

Herein, we report an organic field effect transistor (OFET) with an extended-gate modified by an artificial receptor for the detection of mercury(II) ions (Hg(2+)) in water. The sensor device is easy to fabricate, reusable, disposable, and portable. Thus OFET sensors could be applied for low-cost on-site detection of Hg(2+).
A Concurrent Transmission Control Protocol (2006)

Concurrent transfer is a feasible solution to improve the efficiency and reliability of data communication. In this study, we developed a concurrent transmission control protocol (cTCP), which is based on the TCP but allows concurrent multi-path transfer. Our cTCP effectively minimizes the impact of packet reordering problem under concurrent transfer. Our experimental result confirms that the cTCP can achieve theoretical optimal or a near optimal performance
Machine learning-based e-commerce platform repurchase customer prediction model (2020)

In recent years, China's e-commerce industry has developed at a high speed, and the scale of various industries has continued to expand. Service-oriented enterprises such as e-commerce transactions and information technology came into being. This paper analyzes the shortcomings and challenges of traditional online shopping behavior prediction methods, and proposes an online shopping behavior analysis and prediction system. The paper chooses linear model logistic regression and decision tree based XGBoost model. After optimizing the model, it is found that the nonlinear model can make better use of these features and get better prediction results. In this paper, we first combine the single model, and then use the model fusion algorithm to fuse the prediction results of the single model. The purpose is to avoid the accuracy of the linear model easy to fit and the decision tree model over-fitting. The results show that the model constructed by the article has further improvement than the single model. Finally, through two sets of contrast experiments, it is proved that the algorithm selected in this paper can effectively filter the features, which simplifies the complexity of the model to a certain extent and improves the classification accuracy of machine learning. The XGBoost hybrid model based on p/n samples is simpler than a single model. Machine learning models are not easily over-fitting and therefore more robust.
Synthesis and photoinitiation properties of a novel quaternary ammonium tetraphenylborate salt (2006)

Abstract Quaternary ammonium salts are photobase generators. Recently, we prepared a novel quaternary ammonium tetraphenylborate salt bearing a 6‐methoxynaphthoylmethyl group. The structure of the products was confirmed by elemental analysis and 1 H‐NMR. Thermogravimetry showed its good thermostability. UV spectra and fluorescence emission spectra of the samples were studied. A mass spectrometry method for the analysis of the tertiary amine and other fragments produced by photolysis was established. Photolysis was found to produce both tertiary amine and free radicals. Therefore, the products of photolysis not only could cause thermal curing of epoxide but also could initiate the free‐radical polymerization of acrylate or methyl acrylate monomer. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 100: 399–405, 2006
Electromagnetic degrees of freedom of an optical system (2000)

We present a rigorous electromagnetic formalism for defining, evaluating, and optimizing the degrees of freedom of an optical system. The analysis is valid for the delivery of information with electromagnetic waves under arbitrary boundary conditions communicating between domains in three-dimensional space. We show that, although in principle there is an infinity of degrees of freedom, the effective number is finite owing to the presence of noise. This is in agreement with the restricted classical theories that showed this property for specific optical systems and within the scalar and paraxial approximations. We further show that the best transmitting and receiving functions are the solutions of well-defined eigenvalue equations. The present approach is useful for understanding and designing modern optical systems for which the previous approaches are not applicable, as well as for application in inverse and synthesis problems.
Protecting Turbomachinery From Self-Excited Rotor Whirl (1965)

Aerodynamic exciting forces have caused severe rotor whirl of axial compressors and turbines. One disturbing force investigated is due to circumferential variation of static pressure acting on the cylindrical surface of rotor, particularly within labyrinth seals. Another aerodynamic disturbing force is due to eccentricity of rotor causing circumferential variation of blade-tip clearance, and a corresponding variation of local efficiency and unbalanced torque. Seal deflection criteria and torque deflection criteria are presented as design guides for stable rotor systems. These criteria, the form of which comes from analysis of rotor dynamics, correlate design parameters of four examples of unstable rotor systems which exhibited whirl.
Evaluation of Gabor-wavelet-based facial action unit recognition in image sequences of increasing complexity (2003)

Previous work suggests that Gabor-wavelet-based methods can achieve high sensitivity and specificity for emotion-specified expressions (e.g., happy, sad) and single action units (AUs) of the Facial Action Coding System (FACS). This paper evaluates a Gabor-wavelet-based method to recognize AUs in image sequences of increasing complexity. A recognition rate of 83% is obtained for three single AUs when image sequences contain homogeneous subjects and are without observable head motion. The accuracy of AU recognition decreases to 32% when the number of AUs increases to nine and the image sequences consist of AU combinations, head motion, and non-homogeneous subjects. For comparison, an average recognition rate of 87.6% is achieved for the geometry-feature-based method. The best recognition is a rate of 92.7% obtained by combining Gabor wavelets and geometry features.
Evolution of somatic hypermutation and gene conversion in adaptive immunity (1998)

Examples of somatic hypermutation of antigen receptor genes can be seen in most lineages of vertebrates, including the cartilaginous fish. Analysis of the phylogenetic data reveals that two distinctive features of the mechanism are shared by most species studied: the mutation hot spot sequence AGY, and a preponderance of point mutations. These data suggest that some of the components of the machinery are shared between ectotherms and mammals. However, unique characters in particular species may have occurred by independent recruitment of novel factors onto the mechanism. A spotty phylogenetic distribution of gene conversion has also been revealed and can be explained if the two mechanisms share some characteristics. Both mutation and conversion require transcription-related sequences and/or factors. We theorized that targeting to V genes can be attained by a paused replication fork that has collided with a transcription complex stalled by a defective Ig transcription activator; the paused replication fork results in recruitment of an error-prone translesion synthesis DNA polymerase (somatic hypermutation) or of DNA repair mechanisms with homologous recombination (gene conversion). In addition, the pathway recruited in different species may be directed by the degree of homology among V genes.
Compensation is not enough [fault-handling and compensation mechanism] (2004)

An important problem in designing infrastructure to support business-to-business integration (B2Bi) is how to cancel a long-running interaction (either because the user has changed their mind, or in response to an unrecoverable failure). We review the fault-handling and compensation mechanism that is now used in most workflow products and business process modeling standards. We then use an e-procurement case-study to extract a set of requirements for an effective cancellation mechanism, and we show that the standard approach using fault-handling, and compensation transactions is not adequate to meet these requirements.
Pediatric Spinal Deformities (2002)

LEARNING OBJECTIVES: After reading this article, the participant should be able to: Recall the natural history of pediatric spinal deformities.Describe treatment options for adolescent idiopathic scoliosis.Describe treatment options for neuromuscular deformities.
Electrochemical Synthesis of CeB6 Nanotubes (2014)

This work presents the results of joint electroreduction of tetrafluorborate and cerium-ions, and determines the conditions of electrochemical synthesis of cerium borides in KCl-NaCl melts at the 973 K on tungsten electrode by the linear and cyclic voltammetry. Based on the current-voltage studies the optimal modes of cerium boride electrodeposition were found.
The macrolactins, a novel class of antiviral and cytotoxic macrolides from a deep-sea marine bacterium (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe macrolactins, a novel class of antiviral and cytotoxic macrolides from a deep-sea marine bacteriumK. Gustafson, M. Roman, and William FenicalCite this: J. Am. Chem. Soc. 1989, 111, 19, 7519–7524Publication Date (Print):September 1, 1989Publication History Published online1 May 2002Published inissue 1 September 1989https://pubs.acs.org/doi/10.1021/ja00201a036https://doi.org/10.1021/ja00201a036research-articleACS PublicationsRequest reuse permissionsArticle Views1268Altmetric-Citations222LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Analysis and design of polysilicon thermal flexure actuator (1999)

An analytical model that can accurately predict the performance of a polysilicon thermal flexure actuator has been developed. This model is based on an electrothermal analysis of the actuator, incorporating conduction heat transfer. Heat radiation from the hot arm of the actuator to the cold arm is also estimated. Results indicate that heat radiation becomes significant only at high input power, and conduction heat losses to both the substrate and the anchor are mainly responsible for the operating temperature of the actuator under routine operations. Actuator deflection is computed based on elastic analysis of structures. To verify the validity of the model, polysilicon thermal flexure actuators have been fabricated and tested. Experimental results are in good agreement with theoretical predications except at high input power. An actuator with a 240 μm long, 2 μm thick, 3 μm wide hot arm and a 180 μm long, 12 μm wide cold arm deflected up to 12 μm for the actuator tip at an input voltage of 5 V while it could be expected to deflect up to 22 μm when a 210 μm long cold arm is used.
A study of characteristics of motorway vehicle breakdown duration (2002)

This paper presents an analysis of vehicle breakdown duration on motorways. The distribution of breakdown duration was shown to be statistically significantly different for three categories of vehicle type and were shown to conform to a Weibull distribution. A predictive vehicle breakdown duration model was developed, based on fuzzy logic. The variables used in this model were: vehicle type, breakdown time, breakdown location and reporting mechanism. The performance of the model was tested with encouraging results. Clustering of data was shown to be due to rounding errors when the operator reported an incident duration of 60 and 120 minutes. The unexplained variation in the model was due to the limitations in the specification of the model parameters. This was because the incident data set available was incomplete. This paper highlights the need for standardisation in the recording of data used in incident management.
Carbon Nanofilaments in Heterogeneous Catalysis: An Industrial Application for New Carbon Materials? (2001)

Special carbon! Carbon nanofilaments differ from graphite and soot catalysts in their high stability during the oxidative dehydrogenation of ethylbenzene to styrene. The high yields of styrene achieved suggest that a first industrial application of carbon nanofilaments in catalysis is possible.
Variational Information Maximization in Gaussian Channels (2004)

Abstract: Recently, we introduced a simple variational bound on mutual information, that resolves some of the difficulties in the application of information theory to machine learning. Here we study a specific application to Gaussian channels. It is well known that PCA may be viewed as the solution to maximizing information transmission between a high dimensional vector x and its low dimensional representation y. However, such results are based on assumptions of Gaussianity of the sources x. In this paper, we show how our mutual information bound, when applied to this arena, gives PCA solutions, without the need for the Gaussian assumption. Furthermore, it naturally generalizes to providing an objective function for Kernel PCA, enabling the principled selection of kernel parameters. Keywords: variational methods, mutual information, information maximization, kernel methods, PCA, kernel PCA, approximate learning, Gaussian channel Copyright c 2004 by The University of Edinburgh. All Rights Reserved The authors and the University of Edinburgh retain the right to reproduce and publish this paper for non-commercial purposes. Permission is granted for this report to be reproduced by others for non-commercial purposes as long as this copyright notice is reprinted in full in any reproduction. Applications to make other use of the material should be addressed