gebhart/patrepeval huggingface dataset:
Effective Design-Based Model Selection for Definitive Screening Designs (2016)

Since their introduction by Jones and Nachtsheim in 2011 Jones, B., and Nachtsheim, C. J. (2011), “A Class of Three-Level Designs for Definitive Screening in the Presence of Second-Order Effects,” Journal of Quality Technology, 43, 1–15.[Taylor & Francis Online], [Web of Science ®] , [Google Scholar], definitive screening designs (DSDs) have seen application in fields as diverse as bio-manufacturing, green energy production, and laser etching. One barrier to their routine adoption for screening is due to the difficulties practitioners experience in model selection when both main effects and second-order effects are active. Jones and Nachtsheim showed that for six or more factors, DSDs project to designs in any three factors that can fit a full quadratic model. In addition, they showed that DSDs have high power for detecting all the main effects as well as one two-factor interaction or one quadratic effect as long as the true effects are much larger than the error standard deviation. However, simulation studies of model selection strategies applied to DSDs can disappoint by failing to identify the correct set of active second-order effects when there are more than a few such effects. Standard model selection strategies such as stepwise regression, all-subsets regression, and the Dantzig selector are general tools that do not make use of any structural information about the design. It seems reasonable that a modeling approach that makes use of the known structure of a designed experiment could perform better than more general purpose strategies. This article shows how to take advantage of the special structure of the DSD to obtain the most clear-cut analytical results possible.
A Randomized, Placebo Controlled Pilot Trial of Botulinum Toxin for Paratonic Rigidity in People with Advanced Cognitive Impairment (2014)

ClinicalTrials.Gov NCT02212119.
Melphalan and dexamethasone for patients with multiple myeloma who are not candidates for autologous stem cell transplantation. (2007)

The combination of melphalan and dexamethasone is safe and effective in patients with multiple myeloma who are not candidates for autologous stem cell transplantation.
Social behaviour and growth rate variation in cultivated tilapia (Oreochromis niloticus). (1997)

This study was undertaken to understand the behavioural causes of growth variation in cultivated fish and to study the genetics of agonistic behaviour vis-a-vis growth rate. The fish studied was a laboratory population of the Nile tilapia, Oreochromis niloticus, being maintained at the Marine Gene Probe Laboratory, Dalhousie University. Ten maternal half-sib families were produced by fertilizing the eggs of each female with the sperm from four different males. The fish within each half-sib family were all pooled together for the behaviour as well as growth experiments, in order to expose each fish to the full range of microenvironments within the half-sib family, and to eliminate replicate variance. Upon termination of the experiments, the male parent of each fish was determined using DNA fingerprinting using microsatellites.
The immune control and cell-to-cell spread of human T-lymphotropic virus type 1 (2003)

Human T-lymphotropic virus type 1 (HTLV-1) varies little in sequence compared with human immunodeficiency virus type 1 (HIV) and it is difficult to detect HTLV-1 mRNA, proteins or virions in fresh blood. But the strong and chronically activated T cell response to the virus indicates that HTLV-1 proteins are expressed persistently. It now appears that the efficiency of an individual's cytotoxic T cell (CTL) response to HTLV-1 is the chief single determinant of that person's provirus load, which can differ between HTLV-1-infected people by more than 10 000-fold. Progress is now being made towards defining this CTL 'efficiency' in terms of host genetics, T cell function, T cell gene expression and mathematical dynamics. Lymphocytes that are naturally infected with HTLV-1 do not produce enveloped extracellular virions in short-term culture and this has reinforced the erroneous conclusion that the virus is latent. But recent evidence shows that HTLV-1 can spread directly between lymphocytes across a specialized, virus-induced cell-cell contact - a 'viral synapse'. Instead of making extracellular virions, HTLV-1 uses the mobility of the host cell to spread within and between hosts. In this review the evidence is summarized on the persistent gene expression of HTLV-1 in vivo, the role of the immune system in protection and pathogenesis in HTLV-1 infection, and the mechanism of cell-to-cell spread of HTLV-1.
Study on the loss reduction of high-efficient high-voltage series induction motors (2011)

On the basis of analyzing the composition of losses in high-efficient high-voltage asynchronous motors, the approaches of increasing the efficiency of the motors is investigated in this paper. The approaches concern with the improvement of material, winding, fan, magnetic groove and so on. By taking the economy and efficiency into account synthetically, the design of the YKK series induction motors is carried on, and it is realized by software simulation.
On the uncertainty inequality as applied to discrete signals (2006)

Given a continuous‐time bandlimited signal, the Shannon sampling theorem provides an interpolation scheme for exactly reconstructing it from its discrete samples. We analyze the relationship between concentration (or compactness) in the temporal/spectral domains of the (i) continuous‐time and (ii) discrete‐time signals. The former is governed by the Heisenberg uncertainty inequality which prescribes a lower bound on the product of effective temporal and spectral spreads of the signal. On the other hand, the discrete‐time counterpart seems to exhibit some strange properties, and this provides motivation for the present paper. We consider the following problem: for a bandlimited signal, can the uncertainty inequality be expressed in terms of the samples, using thestandard definitions of the temporal and spectral spreads of the signal? In contrast with the results of the literature, we present a new approach to solve this problem. We also present a comparison of the results obtained using the proposed definitions with those available in the literature.
Collaborative Tracking Control Of Uav-Ugv (2012)

This paper suggests a fast and stable Target Tracking system in collaborative control of UAV and UGV. Wi-Fi communication range is limited in collaborative control of UAV and UGV. Thus, to secure a stable communications, UAV and UGV have to be kept within a certain distance from each other. But existing method which uses UAV Vertical Camera to follow the motion of UGV is likely to lose a target with a sudden movement change. Eventually, UGV has disadvantages that it could only move at a low speed and not make any sudden change of direction in order to keep track of the target. Therefore, we suggest utilizing AR Drone UAV front camera to track fast-moving and Omnidirectional Mecanum Wheel UGV.
Starve-fed Flow in Co-Rotating Twin Screw Extruders (1992)

Abstract A visual study was performed to determine the mixing abilities in simple conveying sections of the partially-filled, corotating, twin screw extruders (PFCoTSE). The amount of mixing that occurs in the PFCoTSE is heavily dependent on the degree to which the channels are filled. A quasi-quantitative method of measuring the growth of an injected tracer is used in determining mixing. It was determined that the PFCoTSE's mixing sections are linear mixers as can be seen from the fact that an injection of tracer quickly transforms into a line and stays as a line throughout the machine and does not break apart while going through the nip (i.e., no reorientation).
[The possibility of the incorporation of macromolecules, including exogenous DNA, into the germ cells of male mice. The liposome method and Ca-P coprecipitation method]. (1990)

Liposomes loaded with FITC-labeled albumin in the presence of PEG-1,500 are actively sorbed on the membranes of mature spermatozoa and remain attached even after thorough washing. Immature sperm cells are able to incorporate alien DNA carried by liposomes. In contrast, the mature spermatozoa could not incorporate plasmid DNA loaded with positively charged liposomes. Chlortetracycline in Ca-P coprecipitate crystals is tightly fixed in the postacrosomal region of mature sperms. Intensity of staining of chlortetracycline is stimulated by DNA load in Ca-P coprecipitate as well as by DMSO or EDTA. The method of Ca-P coprecipitation could not provide for plasmid DNA incorporation into taure sperms. Foreign DNA incorporation in postacrosomal regions of sperm heads seems quite possible in experiments with dimethylsulphoxide (DMSO).
TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia (2008)

TAR DNA binding protein-43 (TDP-43) is found in ubiquitinated inclusions (UBIs) in some frontotemporal dementias (FTD-U). One form of FTD-U, due to mutations in the valosin containing protein (VCP) gene, occurs with an inclusion body myopathy (IBMPFD). Since IBMPFD brain has TDP-43 in UBIs, we looked for TDP-43 inclusions in IBMPFD muscle. In normal muscle, TDP-43 is present in nuclei. In IBMPFD muscle, TDP-43 is additionally present as large inclusions within UBIs in muscle cytoplasm. TDP-43 inclusions were also found in 78% of sporadic inclusion body myositis (sIBM) muscles. In IBMPFD and sIBM muscle, TDP-43 migrated with an additional band on immunoblot similar to that reported in FTD-U brains. This study adds sIBM and hereditary inclusion body myopathies to the growing list of TDP-43 positive inclusion diseases.
Storing and processing temporal data in a main memory column store (2013)

Managing and accessing temporal data is of increasing importance in industry. So far, most companies model the time dimension on the application layer rather than pushing down the operators to the database, which leads to a significant performance overhead. The goal of this PhD thesis is to develop a native support of temporal features for SAP HANA, which is a commercial in-memory column store database system. We investigate different alternatives to store temporal data physically and analyze the trade-offs arising from different memory layouts which cluster the data either by time or by space dimension. Taking into account the underlying physical representation, different temporal operators such as temporal aggregation, time travel and temporal join have to be executed efficiently. We present a novel data structure called Timeline Index and algorithms based on this index, which have a very competitive performance for all temporal operators beating existing best-of-breed approaches by factors, sometimes even by orders of magnitude. The results of this thesis are currently being integrated into HANA, with the goal of being shipped to the customers as a productive release within the next few months.
Study of Predicting Breakdown Voltage of Stator Insulation in Generator Based on BP Neural Network (2007)

The breakdown voltage plays an important role in evaluating residual life of stator insulation in generator. In this paper, we discussed BP neural network that was used to predict the breakdown voltage of stator insulation in generator of 300MW/18kV. At first the neural network has been trained by the samples that include the varieties of dielectric loss factor tans, the partial discharge parameters and breakdown voltage. Then we tried to predict the breakdown voltage of samples and stator insulations subjected to multi-stress aging by the trained neural network. We found that it's feasible and accurate to predict the voltage. This method can be applied to predict breakdown voltage of other generators which have the same insulation structure and material.
Symbolic interaction: Customer, Lifestyle and Store APP embedded in WeChat (2019)

E-commerce has been rapidly thriving into massive B2C and B2B electronic platforms in China recently, like Taobao and Jingdong. This article is to explore the current trend Chinese entrepreneurs attempt to open up a sort of mobile e- commerce based on the concept of the industry chain. This new type of mobile e-commerce is essentially introduced by a new style of the virtual store, embedded in WeChat, called `applets'. It is important to note that WeChat, as the largest Chinese social media with advanced IT infrastructure, has new media's symbolic power to centralize most sources of the social and technology and to integrate most potential customers for its industry partners. My argument is, based on this power, WeChat acts as the specific symbolic form to exercise all possible business models created by its applets. Accordingly, the Chinese entrepreneurs are seeking for greater opportunities to combine B2C and B2B to develop a new integrative business model ushering in a new commercial age.
Non-invasive blood glucose measurement performance analysis through UWB imaging (2016)

Diabetes is a silent killer disease worldwide. Regular blood glucose level monitoring and healthy life management is the only remedy as this cannot be cured. In conventional way, need to draw a drop of blood by pricking fingertip and measure the glucose level through a device. This creates mental trauma among most of the diabetes patient specially the children. To overcome this problem, a non-invasive and patient friendly way of measurement is essential, which is the focus of this paper. Some investigation have been conducted in non-invasive field but none could stand for a durable period in terms of accuracy, comfort and safety. This paper presents an Ultra-wide band (UWB) microwave imaging and Artificial Intelligence (AI) based a solution with performance analysis to detect blood glucose concentration level non-invasively (i.e., without taking any blood sample). The system consists of a pair of small UWB biomedical planar antennas, UWB transceiver as hardware and an artificial neural network (ANN) with signal acquisition and processing interface as software module. The UWB signal with center frequency of 4.7 GHz was transmitted through one side of left hand and forward scattering signals were received from another side. Characteristic features from received signal were extracted for pattern recognition and detection through ANN. The system exhibits 81% accuracy to detect glucose concentration in blood plasma. Besides, it is user friendly, affordable, safe and can be used with comfort in near future.
Anatomical variations of sphenoid sinus on multi-detector computed tomography and its usefulness in trans-sphenoidal endoscopic skull base surgery (2018)

Background: Knowledge of sphenoid bone and sinus anatomy and its variations is of central importance in transsphenoidal endoscopic skull base surgery. It allows endoscopic surgeon to safely approach the sella turcica, anterior skull base and orbit. The aim of the study was to evaluate the different anatomical variations of the sphenoid sinus that are relevant to trans-sphenoid endoscopic skull base surgery on multi-detector computed tomography.Methods: A prospective observational study of the CT analysis of the anatomical variations and various dimensions of sphenoid sinus relevant to trans-sphenoidal endoscopic neurosurgery was performed in 260 patients (173 male; 87 female).Results: The average presellar width of sphenoid sinus on axial CT scan images was 11.75mm (7.2 to 18.6mm). Average value of maximum width of sphenoid sinus was 30.52 mm (13.1 to 42.2 mm). The most common pattern of inter-sphenoid septum was single septum which was present in 207 patients (79.61%); double inter sphenoid septum in 47 patients (18.1%) and diverging septa in 13 patients (5%). 138 out of 260 subjects (53%) showed at least one septum attached to either carotid protuberance. Most common pattern of pneumatization in sphenoid sinus was sellar type (63.46%). Average suprasellar depth was 10.78 (5.4 to 18.7mm). Average presellar depth of sphenoid sinus was 13.47mm (8.1 to 22.5mm). Average infrasellar depth of sphenoid sinus was 25.46mm (11.9 to 37.9mm). Average presellar height of sphenoid sinus was 21.27mm (13 to 27.6mm).Conclusions: A preoperative review of the sphenoid sinus anatomy by CT allows safer endoscopic management of skull base pathology preventing injury to vital structures surrounding the sphenoid sinus.
Science on the International Stage: Hayakawa (2005)

In September 1945, the young physicist Satio Hayakawa joined a group headed by Osamu Minakawa (Central Meteorological Bureau) and Ryōkichi Sagane (Tokyo University) to inspect the impact of the atomic bomb at Nagasaki. Hayakawa’s job was to measure radioactivity.1 The American physicist Richard P. Feynman whom he would later befriend, had worked on the Manhattan Project that ultimately led to the destruction at Hiroshima and Nagasaki. Ironically, Feynman and other American physicists sought to help Japanese physicists rejoin the international community of science.
ATP-Sensitive K <sup>+</sup> Channels: Paradigm Lost, Paradigm Regained (1995)

In an update of a previous Perspective [L. H. Philipson and D. F. Steiner, Science 268 , 372 (1995)], Philipson discusses the molecular basis for Ksubscript ATP, a potassium current that mediates glucose regulation of insulin secretion. A prediction in the previous Perspective is borne out by a paper in this issue of Science (Inagaki et al. , p. 1166 ), which reports the cloning of a new inward rectifier potassium channel and shows that Ksubscript ATP is formed when this channel combines with the sulfonylurea receptor.
Dynamically supporting unexplored domains in conversational interactions by enriching semantics with neural word embeddings (2014)

Spoken language interfaces are being incorporated into various devices (e.g. smart-phones, smart TVs, etc). However, current technology typically limits conversational interactions to a few narrow predefined domains/topics. For example, dialogue systems for smartphone operation fail to respond when users ask for functions not supported by currently installed applications. We propose to dynamically add application-based domains according to users' requests by using descriptions of applications as a retrieval cue to find relevant applications. The approach uses structured knowledge resources (e.g. Freebase, Wikipedia, FrameNet) to induce types of slots for generating semantic seeds, and enriches the semantics of spoken queries with neural word embeddings, where semantically related concepts can be additionally included for acquiring knowledge that does not exist in the predefined domains. The system can then retrieve relevant applications or dynamically suggest users install applications that support unexplored domains. We find that vendor descriptions provide a reliable source of information for this purpose.
Napakäämityn murtovakokestomagneettitahtikoneen suunnittelu (2005)

Diplomityössä tutustutaan napakäämittyihin murtovakokestomagneettitahtikoneisiin sekä syvennytään niiden suunnitteluun analyyttisen laskennanavulla. Analyyttisen laskennan haasteena on perinteisesti käytettyjen kestomagneettitahtikoneiden laskentayhtälöiden sovittaminen murtovakokäämityille kestomagneettitahtikoneille. Työn lopussa analyyttisen laskennan tuloksia verrataan kenttälaskentaohjelmalla saatuihin tuloksiin. Tärkeimmät analyyttiset yhtälöt sekä laskentamallin rakenne on esitetty työssä.
Adducts of Carbenes with Group II and XII Metallocenes<sup>†</sup> (1998)

The reactions and adducts of 1,3,4,5-tetramethylimidazol-2-ylidene with bis(pentamethylcyclopentadienyl)magnesium, -calcium, -strontium, -barium, or -zinc are described. A consistent tend in the spectroscopic properties and structures of the alkaline earth metallocenes is observed. The adduct between 1,3,4,5-tetramethylimidazol-2-ylidene and bis(pentamethylcyclopentadienyl)zinc shows a structure in which the zinc is only σ-bonded to the three ligating groups. Among the alkaline earth adducts, the σ-bonded interaction to the former carbene center of the 1,3,4,5-tetramethylimidazol-2-ylidene shows the shortest metal−carbon distances in each of the structures but the difference between the carbene−metal and pentamethylcyclopentadienyl−metal distances decreases as the atomic number of the metal increases.
Expression of the bop gene cluster of Halobacterium halobium is induced by low oxygen tension and by light (1991)

The bop gene cluster consists of at least three genes: bop (bacterio-opsin), brp (bacterio-opsin-related protein), and bat (bacterio-opsin activator). We have quantitated transcript levels from these genes in a wild-type and bacterioruberin-deficient mutant of Halobacterium halobium under conditions which affect purple membrane synthesis. In wild-type cultures grown under high oxygen tension in the dark, bop and bat transcript levels were low during steady-state growth and then increased approximately 29- and approximately 45-fold, respectively, upon entry into stationary phase. brp gene transcription remained very low and essentially unchanged under these conditions. In addition, exposure of wild-type cultures growing under high oxygen tension to 30,000 lx of light stimulated expression of all three genes, especially brp. In contrast to the wild-type, transcription from all three genes in the bacterioruberin mutant was very high during steady-state growth under high oxygen tension in the dark. Cultures of the bacterioruberin mutant were shifted at early stationary phase to low oxygen tension to determine whether oxygen concentrations lower than those present in stationary phase would induce transcription of the bop gene cluster in this strain. Indeed, transcription was induced, suggesting that the bop gene cluster is not completely uncoupled from regulation by oxygen tension in the bacterioruberin mutant. From these data, we propose a regulatory model involving two different mechanisms: (i) bat gene expression is induced under conditions of low oxygen tension and the bat gene product activates bop gene expression and (ii) light induces brp transcription, which stimulates or modulates bat transcription.
The relationship between exercise intensity and performance in drills aimed at improving the proficiency, technical and tactical skills of basketball players (2009)

Training programs for basketball players are often targeted at improving game tactics. The main objectives of this study were: a) to establish a relationship between exercise intensity and performance in basketball technical and tactical proficiency drills; and b) to determine the existing relationship between the opposition exerted by a direct opponent and the exercise intensity needed for the attacker to overcome this opposition. The study participants were 11 basketball players aged 17-18 years who had reached the top level in their age category. The players first underwent an incremental exercise test to establish heart rates corresponding to the ventilatory thresholds VT1 and VT2 as a measure of exercise intensity. Next, they performed a set of game-related technical/tactical exercises in conditions of defensive numerical equality or superiority. In these tests, physiological variables were recorded in contingency tables along with measures of the players¿ technical prowess and tactical decision capacity both as qualitative scores and quantitative variables. Our findings indicate that subjects in more physically demanding situations made more incorrect tactical decisions. Also, in conditions of greater opposition by the defence player, the attacker showed a worse tactical decision score and had to make a greater physical effort to overcome this opposition.