gebhart/patrepeval huggingface dataset:
Silylene Extrusion from a Silane:  Direct Conversion of Mes<sub>2</sub>SiH<sub>2</sub>to an Iridium Silylene Dihydride (1999)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTSilylene Extrusion from a Silane: Direct Conversion of Mes2SiH2 to an Iridium Silylene DihydrideJonas C. Peters, Jay D. Feldman, and T. Don TilleyView Author Information Department of Chemistry, University of California at Berkeley, Berkeley, California 94720-1460 Cite this: J. Am. Chem. Soc. 1999, 121, 42, 9871–9872Publication Date (Web):October 8, 1999Publication History Received8 July 1999Published online8 October 1999Published inissue 1 October 1999https://doi.org/10.1021/ja992367dCopyright © 1999 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views1796Altmetric-Citations137LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (48 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Anions,Group 14 compounds,Inorganic compounds,Ligands,Transition metals Get e-Alerts
Rapamycin attenuates depression and anxiety‐like behaviors through modulation of the NLRP3 pathway in pentylenetetrazole‐kindled male Wistar rats (2021)

Our results showed that the inhibitory effect of mTOR inhibitor (rapamycin) on reactive oxygen species production during NLRP3 inflammasome activation could bring about behavioral alterations in anxiety and depression.
Thiocarbamate herbicide-inducible nonheme haloperoxidase of Rhodococcus erythropolis NI86/21 (1997)

During biodegradation of thiocarbamate herbicides by Rhodococcus erythropolis NI86/21, a protein with an M(r) of 30,000 is induced (I. Nagy, G. Schoofs, F. Compernolle, P. Proost, J. Vanderleyden, and R.De Mot, J. Bacteriol. 177:676-687, 1995). Based on N-terminal sequence data for the protein purified by two-dimensional electrophoresis, the corresponding structural gene, thcF, was cloned and sequenced. The deduced protein sequence of ThcF is homologous to those of nonheme haloperoxidases. A particularly high level of sequence identity (72.6%) was observed for the chloroperoxidase from Pseudomonas pyrrocinia. A polyclonal antibody against the latter enzyme cross-reacted with ThcF either produced by the original Rhodococcus cells or overexpressed heterologously in Escherichia coli. In both thiocarbamate-grown Rhodococcus cells and E. coli cells expressing thcF, the haloperoxidase activity of ThcF was demonstrated. The thiocarbamate-inducible R. erythropolis ThcF protein represents the first (nonheme) haloperoxidase to be identified in a nocardioform actinomycete.
New ruthenium(II) heteroleptic complexes containing the 4-(2-pyridyl)pyrimidine ligand with amine and amino acid substituents (1999)

New 4-(2-pyridyl)pyrimidines (L) have been synthesized in high yields by condensing enaminones with the appropriate carboxamidine or guanidine under basic conditions. These asymmetric bidentate diimine ligands coming from a one-step functionalization of amine and amino acid groups were complexed to ruthenium to obtain new heteroleptic complexes of type [Ru(bpy)2(L)]2+. The ligands and complexes have been characterized by usual analytical methods, and the crystallographic study of one complex has been performed. Their spectroscopic and electrochemical properties have been investigated. ZINDO Calculations show that in the MLCT excited state the electron is mainly localized on the pyridylpyrimidine ligand. On the basis of electrochemical data, the first reduction potential of the complexes has been assigned to the redox couple involving this ligand.
Efficacy of Systemic Cyclosporine A and Amniotic Membrane on Rabbit Conjunctival Limbal Allograft Rejection (2005)

A model of rejection of conjunctival limbal transplantation was developed in the rabbit. Intramuscularly injected CsA effectively prevents limbal allograft rejection. Human AM is not useful for this purpose.
Macrophage colony-stimulating factor promotes the survival of osteoclast precursors by up-regulating Bcl-XL (2002)

Macrophage colony-stimulating factor (M-CSF) is known as one of the factors essential for osteoclast development. In the present study, we examined effects of M-CSF on the apoptotic pathway of osteoclast precursors and their underlying molecular mechanisms. Osteoclast precursors underwent apoptosis in the absence of M-CSF, even in the presence of receptor activator of NF-kappakB ligand (RANKL). Active caspase-3 and -9 were detected in the osteoclast precursors and treatments of precursors with their specific inhibitors (Z-DEVD-FMK and Z-LEHD-FMK) decreased the apoptosis. M-CSF decreased apoptosis in a dose-dependent manner with decreasing in active caspases-3 and -9 levels and up-regulating Bcl-X(L). Those effects of M-CSF on inhibiting apoptosis of osteoclasts precursor by regulating anti-apoptotic signals was more effective when combined with RANKL. These results demonstrate that M-CSF acts as a survival factor for the osteoclast precursors. Furthermore, it is believed that the apoptosis of osteoclast precursors may be involved in the activation of caspase-9 and that M-CSF may promote their survival through Bcl-X(L)-induced inhibition of caspase-9 activation.
Low Threshold Service Design: Desktop Walkthrough (2016)

This paper introduces the first academic characterisation of the desktop walkthrough technique. Desktop walkthrough is considered here as a service design technique using a collaboratively built miniature environment to construct knowledge about a specific service. It is further examined as a technique for rapidly exploring and designing a service concept. The analytical lens of the paper is outlined from socio-cultural theories on human development where any human action is developed from, and emulated by, social interactions and the intellectual and physical artefacts herein. The analysis shows that desktop walkthrough enabled teams to design a holistic service journey with low threshold usage, and provided a means for exploring and designing the complexity of customer journeys and the backstage organizational processes.
Safe manual memory management (2007)

We present HeapSafe, a tool that uses reference counting to dynamically verify the soundness of manual memory management of C programs. HeapSafe relies on asimple extension to the usual malloc/free memory management API: delayed free scopes during which otherwise dangling references can exist. Porting programs for use with HeapSafe typically requires little effort (on average 0.6% oflines change), adds an average 11% time overhead (84% in the worst case), and increases space usage by an average of 13%. These results are based on portingover half a million lines of C code, including perl where we found sixpreviously unknown bugs.Many existing C programs continue to use unchecked manual memorymanagement. One reason is that programmers fear that moving to garbage collection is too big a risk. We believe that HeapSafe is a practical way toprovide safe memory management for such programs. Since HeapSafe checks existing memory management rather than changing it, programmers need not worrythat HeapSafe will introduce new bugs; and, since HeapSafe does not managememory itself, programmers can choose to deploy their programs without HeapSafe if performance is critical (a simple header file allows HeapSafe programs to compile and run with a regular C compiler). In contrast, we foundthat garbage collection, although faster, had much higher space overhead, and occasionally caused a space-usage explosion that made the program unusable.
Structural and electrical properties of a metallic rough-thin-film system deposited on liquid substrates (1996)

A rough-thin-film system, deposited on silicone oil drop surfaces by a rf-magnetron sputtering method, has been fabricated and its structure as well as I-V characteristics have been studied. A characteristic surface morphology at the micrometer scale is observed. The anomalous deposition rate, which strongly depends on the nominal film thickness, can be interpreted under the assumption of the second evaporating and the penetrating effects. We find ${\mathit{I}}_{\mathit{c}}$\ensuremath{\propto}${\mathit{R}}_{0}^{\mathrm{\ensuremath{-}}\mathrm{\ensuremath{\alpha}}}$, with \ensuremath{\alpha}=0.52\ifmmode\pm\else\textpm\fi{}0.06, where ${\mathit{R}}_{0}$ and ${\mathit{I}}_{\mathit{c}}$ are the zero power resistance and the breakdown current, respectively. The importance of the liquid substrates is discussed. \textcopyright{} 1996 The American Physical Society.
Limiting Highway Access (1940)

IAlong the 30.5 miles of the Washington Boulevard outside of Baltimore and Washington, there are six hundred and eighteen business establishments, or an average of one every five hundred and twenty feet on each side of the highway, in addition to six hundred and sixty-five rest-
Influence of functional organic groups on the structure of CTAB templated organosilica thin films (2004)

Highly ordered mesoporous organosilica thin films containing functional organic terminal groups covalently bonded to the silica matrix were synthesized by co-condensation of tetraethylorthosilicate (TEOS) and organotriethoxysilane RSi(OEt)3 (R = Cl(CH2)3, CN(CH2)3) in the presence of cetyltrimethylammonium bromide (CTAB) as structure directing agent under acidic conditions. The influence of the nature and concentration of these organic groups on the structure of the thin films is evidenced by Grazing Incidence Small Angle Scattering (GISAXS) and X-ray reflectivity. We show that the introduction of chloropropyl groups strongly affects the structure of these films while cyanopropyl groups weakly perturb it. In the case of the chloropropyl groups, the presence of trans and gauche conformers in the films is clearly evidenced by using micro-Raman spectrometry. Their effects on the phase behaviour versus the concentration are discussed.
Glyceraldehyde-3-phosphate Dehydrogenase Is Required for Vesicular Transport in the Early Secretory Pathway (2001)

Protein transport in the early secretory pathway requires Rab2 GTPase. This protein promotes the recruitment of soluble components that participate in protein sorting and recycling from pre-Golgi intermediates (vesicular tubular clusters (VTCs)). We previously reported that a constitutively activated form of Rab2 (Q65L) as well as Rab2 wild type promoted vesicle formation from VTCs. These vesicles contained Rab2, beta-COP, p53/gp58, and protein kinase Ciota/lambda but lacked anterograde-directed cargo. To identify other candidate Rab2 effectors, the polypeptide composition of the vesicles was further analyzed. We found that vesicles released in response to Rab2 also contained the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH). To study the relationship of this enzyme to Rab2 function, we performed a quantitative binding assay to measure recruitment of GAPDH to membrane when incubated with Rab2. Rab2-treated microsomes showed a 5-10-fold increase in the level of membrane-associated GAPDH. We generated an affinity-purified anti-GAPDH polyclonal to study the biochemical role of GAPDH in the early secretory pathway. The antibody arrests transport of a reporter molecule in an assay that reconstitutes ER to Golgi traffic. Furthermore, the affinity-purified antibody blocked the ability of Rab2 to recruit GAPDH to membrane. However, the antibody did not interfere with Rab2 stimulated vesicle release. These data suggest that GAPDH is required for ER to Golgi transport. We propose that membranes incubated with anti-GAPDH and Rab2 form "dead end" vesicles that are unable to transport and fuse with the acceptor compartment.
RFID tag antenna matching to frequency dependent microchip impedance (2008)

The paper demonstrates that the reflection coefficient calculated using the frequency dependent microchip impedance shows better agreement between the simulation and measurement than power reflection coefficients calculated from fixed frequency microchip impedances. Thus it is recommended to consider this procedure while designing tag antennas for better performance across the desired frequency band of operation.
Preparation of anatase powders from fluorine-complexed titanium(iv) aqueous solution using microwave irradiation (2000)

The microwave radiation activated precipitation of titanium dioxide from homogeneous aqueous solutions of titanium–fluoro complexes and boric acid has been carried out in batch reactors. Crystalline anatase powders with narrow monodisperse size distribution have been obtained in a short time, at low temperature and atmospheric pressure. Microwave power, irradiation time and precursor concentration determine the properties of the obtained materials, i.e. crystal size, powder aggregate morphology and BET surface area. The obtained materials do not show photocatalytic activity, probably due to a considerable fluoride content that is in the range of 2–5%.
Effects of zearalenone and/or tamoxifen on swine and mink reproduction (1995)

Tamoxifen (TAM), which binds to estrogen receptors and can act as an estrogen antagonist, was incorporated into the diets of swine and mink to determine if it would ameliorate the effects of the estrogenic mycotoxin zearalenone (ZEN). Sows and female mink were fed diets containing 2 ppm (swine) or 20 ppm (mink) ZEN and/or 10 ppm TAM from day 30 of gestation through weaning (swine) or from 2 months prior to breeding through weaning (mink). The diets containing ZEN and/or TAM did not adversely affect reproduction in the sows. Although some hyperestrogenic effects on testes, uterine and ovarian weights were observed in the F1 piglets at 21 days of age, subsequent breeding performance was not affected. All the female mink exposed to ZEN mated, but only 25% whelped. No mink fed TAM (singly or in combination with ZEN) mated. Necropsy of these unmated females fed TAM revealed consistent severe pyometra. Histological examination of the reproductive tracts of the ZEN, TAM and ZEN + TAM-treated mink showed similar alterations, including ovarian follicular atrophy and degeneration, and mild to severe uterine atrophy, pyometra and endometritis. The results of these studies indicate that TAM was not effective in ameliorating the hyperestrogenic effects of ZEN in swine and mink, but rather it acted as an estrogen agonist.
miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia (2011)

It is increasingly recognized that the mechanisms underlying ischemic cell death are sexually dimorphic. Stroke-induced cell death in males is initiated by the mitochondrial release of apoptosis-inducing factor, resulting in caspase-independent cell death. In contrast, ischemic cell death in females is primarily triggered by mitochondrial cytochrome c release with subsequent caspase activation. Because X-linked inhibitor of apoptosis (XIAP) is the primary endogenous inhibitor of caspases, its regulation may play a unique role in the response to injury in females. XIAP mRNA levels were higher in females at baseline. Stroke induced a significant decrease in XIAP mRNA in females, whereas no changes were seen in the male brain. However, XIAP protein levels were decreased in both sexes after stroke. MicroRNAs (miRNAs) predominantly induce translational repression and are emerging as a major regulators of mRNA and subsequent protein expression after ischemia. The miRNA miR-23a was predicted to bind XIAP mRNA. miR-23a directly bound the 3' UTR of XIAP, and miR-23a inhibition led to an increase in XIAP mRNA in vitro, demonstrating that XIAP is a previously uncharacterized target for miR-23a. miR-23a levels differed in male and female ischemic brains, providing evidence for sex-specific miRNA expression in stroke. Embelin, a small-molecule inhibitor of XIAP, decreased the interaction between XIAP and caspase-3 and led to enhanced caspase activity. Embelin treatment significantly exacerbated stroke-induced injury in females but had no effect in males, demonstrating that XIAP is an important mediator of sex-specific responses after stroke.
Elastic reverse-time migration using the Helmholtz decomposition in the time domain (2012)

In this paper, we propose a new time-domain elastic migration technique. By exploiting the back-propagation technique, the excessive computational burden could be efficiently minimized. In addition, the implementation of the Helmholtz decomposition as the wavefield separation technique can enhance the accuracy of the final migrated images using the multi-component data in an elastic medium. Our migration algorithm is tested using the synthetic seismic data generated using the SEG/EAGE salt-dome and Overthrust models. Our new migration technique can image the location and shape of the target zone more clearly than conventional migration methods without wavefield separation.
Time-Based Analog to Digital Converters. (2009)

Low-power, small analog-to-digital converters (ADCs) have numerous applications in areas ranging from power-aware wireless sensing nodes for environmental monitoring to biomedical monitoring devices in point-of-care (PoC) instruments. The work focuses on ultra-low-power, and highly integrated implementations of ADCs, in nanometer-scale complementary metal-oxide-semiconductor (CMOS) very large scale (VLSI) integrated circuit fabrication technologies. In particular, we explore time-based techniques for data conversion, which can potentially achieve significant reductions in power consumption while keeping silicon chip area small, compared to today’s state-of-the-art ADC architectures. Today, digital integrated circuits and digital signal processors (DSP) are taking advantage of technology scaling to achieve improvements power, speed, and cost. Meanwhile, as technology scaling reduces supply voltage and intrinsic transistor gain, analog circuit designers face disadvantages. With these disadvantages of technology scaling, two new broad trends have emerged in ADC research. The first trend is the emergence of digitally-assisted analog design, which emphasizes the relaxation of analog domain precision and the recovering accuracy (and performance) in the digital domain. This approach is a good match to the capabilities of fine line technology and helps to reduce power consumption. The second trend is the representation of signals, and the processing of signals, in the time domain. Technology scaling and its focus on high-performance digital systems offers better time resolution by reducing the gate delay. Therefore, if we represent a signal as a period of time, rather than as a voltage, we can take advantage of technology scaling, and potentially reduce power consumption and die area. This thesis focuses on pulse position modulation (PPM) ADCs, which incorporate time-domain processing and digitally assisted analog circuitry. This architecture reduces power consumption and area significantly, without sacrificing performance. The input signal is pulse position modulated and the analog information is carried in the form of timing intervals. Timing measurement accuracy presents a major challenge and we present various methods in which accuracy can be achieved using CMOS processes. This ‘digital’ approach is more power efficient compared with pure analog solutions, utilized for amplitude measurement of input signals.
Monoclonal antibodies against the iron regulated outer membrane Proteins of Acinetobacter baumannii are bactericidal (2001)

This proves that iron uptake via IROMPs,which is mediated through siderophores,may have an important role in the survival of A.baumanii inside the host,and helps establishing the infection.
Electrical Stimuli Patterned After the Theta-Rhythm Induce Multiple Forms of LTP (2001)

The induction of long-term potentiation (LTP) by high-frequency stimulation is considered an acceptable model for the study of learning and memory. In area CA1 calcium influx through N-methyl-D-aspartate receptors (NMDARs; nmdaLTP) and/or L-type voltage-dependent calcium channels (vdccLTP) results in distinct forms of LTP. In the light of significant accumulation of knowledge about patterns of naturally occurring activity in the intact animal, we examined whether the application of stimuli patterned after natural activity induced nmdaLTP and/or vdccLTP. In rat hippocampal slices we examined LTP induced by three types of patterned stimulation short (S-TBS), long (L-TBS), and high-intensity long theta-patterned stimulation (HL-TBS). The patterns of stimulation were applied in control, nifedipine (blocks vdccLTP), D,L-2-amino-5-phosphonovaleric acid (APV; blocks nmdaLTP), or APV and nifedipine containing media. We found that S-TBS resulted in LTP that was completely attenuated in the presence of APV but was unaffected by nifedipine. Thus S-TBS results in the selective induction of nmdaLTP. L-TBS resulted in LTP that was completely blocked by APV and only partially blocked by nifedipine. Therefore L-TBS results in a compoundLTP consisting of both nmdaLTP and vdccLTP components. In the presence of APV, HL-TBS resulted in vdccLTP, and when APV and nifedipine were both present, LTP was completely blocked. Thus HL-TBS results in a vdccLTP in isolation when APV is present. We also examined saturation of S-TBS-induced LTP (nmdaLTP) by applying S-TBS at short intervals. When nifedipine was present, multiple S-TBS trains resulted in a substantially smaller final LTP as compared with controls. We conclude that multiple bursts of S-TBS eventually summate to result in compoundLTP. Stimuli patterned after innate rhythms in the hippocampus effectively induce nmdaLTP (S-TBS), compoundLTP (L-TBS), or vdccLTP (HL-TBS).
Paint Thickness Measurement Using Acoustic Interference (2006)

A novel method of determining the thickness of a paint coating over composites is presented. A sinusoidal ultrasonic wave modulated with a low-duty-cycle pulse train is interfered with its own reflection off the paint-composite interface. An amplitude profile periodic in frequency is observed after interference. Measurement is first made with the transducer facing air and then with the transducer facing the sample. The frequency shift of a chosen minimum is used to calculate the paint coating thickness. A method using two frequencies to increase the range of thickness measurement and improve the resolution is also presented. The method has been shown to yield an accuracy better than 3%