gebhart/patrepeval huggingface dataset:
Extensas nieblas invernales en la cuenca del Duero (2002)

Se realiza una novedosa y necesaria (para riesgos naturales) aplicación geográfica de la teledetección y del análisis interniveles de la dinámica atmosférica para explicar la formación y localización de extensas nieblas persistentes e intensas en el interior de la Península Ibérica. Concretamente, las imágenes de los satélites Meteosat y NOAA (de varias horas cada día) permitieron localizar en el Oeste y Centro de la Cuenca del Duero la persistencia de dichas nieblas, que se originan con una dinámica atmosférica anticiclónica (de aire húmedo y relativamente cálido) diversificada en superficie por la configuración geomorfológica. Se trata de nieblas asociadas a pérdidas térmicas nocturnas por irradiación con escasa nubosidad, que se acumulan en ámbitos bajos debido a advecciones de aire enfriado mediante vientos catabáticos débiles. En valles y bajas campiñas las nieblas generan inversiones térmicas y cohesionan variados efectos meteorológicos, que corresponden a cinco observatorios completos, analizados en parte mediante correlaciones estadísticas.
Differences in Magnitude and Duration of Opioid-Induced Respiratory Depression and Analgesia with Fentanyl and Sufentanil (1990)

The magnitude and duration of analgesia and respiratory depression induced by fentanyl (1.0, 2.0, and 4.0 micrograms/kg) and sufentanil (0.1, 0.2, and 0.4 microgram/kg) after intravenous administration over 30 s were measured in 30 healthy young adult male volunteers divided into three groups and studied in a double-blind, randomized fashion. Each volunteer received one dose of fentanyl or sufentanil and no sooner than 48 h later, the corresponding equipotent dose of the other opioid. End-tidal CO2 and ventilatory and occlusion pressure responses to CO2 rebreathing were used to measure drug-induced respiratory effects. Analgesic effects were assessed by changes in the pain threshold to electric shock applied to the forearm. Plasma levels of fentanyl and sufentanil were measured by radioimmunoassay. Testing and sampling intervals were 5, 30, 60, 90, 120, 240, 300, and 360 min after drug administration. The magnitude and duration of depression of the ventilatory and occlusion pressure response were significantly less with sufentanil compared with fentanyl, irrespective of dose. Ventilatory and occlusion pressure responses returned to control values by 30 and 30 min, respectively, after sufentanil and by 240 and 120 min, respectively, after fentanyl. Statistically significant elevations of the pain threshold were, however, greater and longer lasting after sufentanil compared with fentanyl. Pain threshold returned to control values 180 min after sufentanil but only 90 min after fentanyl. These results suggest that sufentanil may provide better patient comfort with less respiratory depression than does fentanyl.
Equilibrium thin films on rough surfaces. 1. Capillary and disjoining effects (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEquilibrium thin films on rough surfaces. 1. Capillary and disjoining effectsJ. B. Sweeney, T. Davis, L. E. Scriven, and J. A. ZasadzinskiCite this: Langmuir 1993, 9, 6, 1551–1555Publication Date (Print):June 1, 1993Publication History Published online1 May 2002Published inissue 1 June 1993https://pubs.acs.org/doi/10.1021/la00030a021https://doi.org/10.1021/la00030a021research-articleACS PublicationsRequest reuse permissionsArticle Views402Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Crosstalk noise model for shielded interconnects in VLSI-based circuits (2004)

Placing shields around a victim signal line is a common way to enhance signal integrity while minimizing delay uncertainty. An analytic model of the peak noise is developed for shielded interconnects, based on a pseudo-2/spl pi/ RC model. A design methodology for inserting shields between coupled interconnects, to reduce crosstalk noise, is presented.
The production‐ecological sustainability of cassava, sugarcane and sweet sorghum cultivation for bioethanol in Mozambique (2011)

Abstract We present an approach for providing quantitative insight into the production‐ecological sustainability of biofuel feedstock production systems. The approach is based on a simple crop‐soil model and was used for assessing feedstock from current and improved production systems of cassava for bioethanol. Assessments were performed for a study area in Mozambique, a country considered promising for biomass production. Our focus is on the potential role of smallholders in the production of feedstock for biofuels. We take cassava as the crop for this purpose and compare it with feedstock production on plantations using sugarcane, sweet sorghum and cassava as benchmarks. Production‐ecological sustainability was defined by seven indicators related to resource‐use efficiency, soil quality, net energy production and greenhouse gas (GHG) emissions. Results indicate that of the assessed systems, sugarcane performed better than cassava, although it requires substantial water for irrigation. Targeted use of nutrient inputs improved sustainability of smallholder cassava. Cassava production systems on more fertile soils were more sustainable than those on less fertile soils; the latter required more external inputs for achieving the same output, affecting most indicators negatively and reducing the feasibility for smallholders. Cassava and sweet sorghum performed similarly. Cassava production requires much more labour per hectare than production of sugarcane or sweet sorghum. Production of bioethanol feedstock on cultivated lands was more sustainable and had potential for carbon sequestration, avoiding GHG emissions from clearing natural vegetation if new land is opened.
Comparative Effects of Insulin‐Like Growth Factor II (IGF‐II) and IGF‐II Mutants Specific for IGF‐II/CIM6‐P or IGF‐I Receptors on in Vitro Hematopoiesis (1996)

This report presents the results of studies investigating the effect of insulin-like growth factor II (IGF-II) on the proliferation and differentiation of CD34+ bone marrow cells in serum-substituted liquid cultures. Bone marrow cells were enriched for CD34+ cells and then placed in liquid cultures supplemented with either interleukin 3 (IL-3) or IL-3 and c-kit ligand with and without the addition of IGF-II. When CD34+ cells were incubated with IL-3, cellularity increased throughout four weeks of culture. Cellularity was twofold greater when cultures also contained IGF-II. IGF-II also promoted an increase in cellularity in cultures with IL-3 and c-kit ligand. In combination with IL-3 or IL-3 and c-kit ligand, IGF-II promoted an earlier differentiation of granulocytes, as well as an increase in the number of megakaryocyte lineage cells. There were approximately two-fold more colony-forming units for granulocytes and macrophages (CFU-GM) and burst-forming units for erythroid cells (BFU-E) in cultures containing both IL-3 and IGF-II than in cultures with IL-3 alone. These results demonstrate that in cytokine-supplemented media, physiological concentrations of IGF-II augmented both the proliferation and differentiation of CD34+ bone marrow cells while maintaining a greater number of progenitor cells. To identify the receptors through which IGF-II enhances in vitro hematopoiesis, IGF-II was substituted with one of the mutant forms of IGF-II that selectively interacts with either IGF-II/CIM6-P receptors or with IGF-I and insulin receptors. The results with the mutant forms of IGF-II demonstrate that IGF-II augments in vitro hematopoiesis primarily through its interaction with IGF-I and possibly insulin receptors, rather than IGF-II/CIM6-P receptors.
RF lamb wave resonators in bandpass delta-sigma converters for digital receiver architectures (2007)

Above-IC high-Q (1100) Lamb wave resonators are proposed to replace classical off-chip SAW resonators and LC components to increase the resolution of continuous-time bandpass delta-sigma modulators. Moreover, these resonators are suitable for co-integration with BAW technology and thus make possible highly integrated digital architectures which simultaneously include BAW antenna filters and IF resonators.
LSI Digital Frequency Synthesizer. (1975)

Results are presented on the development of an integrated injection logic (I2L) digital frequency synthesizer (DFS). The prototype DFS was designed to operate at a 4.8 MHz clock rate outputting eight fixed frequencies from dc to 2.4 MHz. The processing, testing and evaluation of I2L logic test cells is reported. The minimum stage delay achieved for a test I2L inverter was 8.7 ns. The design rules applicable to standard cell large scale I2L are discussed. The prototype DFS design, layout and testing is presented. Approximately 640 basic I2L inverters were required to implement the prototype DFS. Average power dissipation at the 4.8 MHz clock rate is estimated to be 20 microW per inverter. The feasibility of future expansion of the DFS to provide 640 frequencies at 4.8 MHz and 128 frequencies at 12.5 MHz clock rate is discussed. (Author)
<i>Aspergillus</i> Protein Degradation Pathways with Different Secreted Protease Sets at Neutral and Acidic pH (2010)

Aspergillus fumigatus grows well at neutral and acidic pH in a medium containing protein as the sole nitrogen source by secreting two different sets of proteases. Neutral pH favors the secretion of neutral and alkaline endoproteases, leucine aminopeptidases (Laps) which are nonspecific monoaminopeptidases, and an X-prolyl dipeptidase (DppIV). Acidic pH environment promotes the secretion of an aspartic endoprotease of pepsin family (Pep1) and tripeptidyl-peptidases of the sedolisin family (SedB and SedD). A novel prolyl peptidase, AfuS28, was found to be secreted in both alkaline and acidic conditions. In previous studies, Laps were shown to degrade peptides from their N-terminus until an X-Pro sequence acts as a stop signal. X-Pro sequences can be then removed by DppIV, which allows Laps access to the following residues. We have shown that at acidic pH Seds degrade large peptides from their N-terminus into tripeptides until Pro in P1 or P'1 position acts as a stop for these exopeptidases. However, X-X-Pro and X-X-X-Pro sequences can be removed by AfuS28 thus allowing Seds further sequential proteolysis. In conclusion, both alkaline and acidic sets of proteases contain exoprotease activity capable of cleaving after proline residues that cannot be removed during sequential digestion by nonspecific exopeptidases.
M3R AESA technology for Extended Air Defence (2008)

This paper focus on the M3R active electronically steered antenna (AESA) system and will describe how this AESA is a step towards a fully digitized antenna with a receiver and an A/D-converter behind every antenna element and a full digital beam forming without using analogue sub arrays. First, it will be explained why extended air defence (that is Air and Missile Defence) requires a multi-function, multibeam radar technology; then M3R radar will be described and the M3R innovative antenna concept implemented in the M3R radar will be presented; The antenna system will be detailed showing the large contribution of the M3R programme to the Thales Building Block Product Policy. The final part shows how M3R antenna architecture is a step towards fully digital radar and multi-static operating mode.
Quercetin, Inflammation and Immunity (2016)

In vitro and some animal models have shown that quercetin, a polyphenol derived from plants, has a wide range of biological actions including anti-carcinogenic, anti-inflammatory and antiviral activities; as well as attenuating lipid peroxidation, platelet aggregation and capillary permeability. This review focuses on the physicochemical properties, dietary sources, absorption, bioavailability and metabolism of quercetin, especially main effects of quercetin on inflammation and immune function. According to the results obtained both in vitro and in vivo, good perspectives have been opened for quercetin. Nevertheless, further studies are needed to better characterize the mechanisms of action underlying the beneficial effects of quercetin on inflammation and immunity.
Cripto, a member of the epidermal growth factor family, is over‐expressed in human pancreatic cancer and chronic pancreatitis (1994)

Cripto is a 188 amino-acid protein containing a central segment that shares amino-acid sequence homology with epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The EGF receptor, EGF and TGF-alpha are expressed in the normal human pancreas, and are over-expressed in human pancreatic cancer. Therefore, in the present study we sought to determine whether cripto is found in the normal human pancreas and whether its expression is altered in pancreatic cancer. Because chronic pancreatitis (CP) is associated with interstitial fibrosis similar to that observed in pancreatic cancer, we also examined cripto expression in pancreatic tissues from patients with CP. In the normal pancreas, cripto immunoreactivity was found at moderate levels in most ductal cells and was present very faintly in a rare acinar cell. In 26 of 58 pancreatic cancers, cripto immunoreactivity was present in many cancer cells. Its presence was associated with advanced tumor stage, but not with shorter post-operative survival. Cripto was also present in acinar and ductal cells adjacent to the cancer cells, and in many ductal atrophic acinar cells in the CP samples. Northern blot analysis revealed a marked increase in cripto mRNA levels in the cancer and CP samples. By densitometry, there was a 11- and 4-fold increase in cripto mRNA levels in pancreatic cancer and CP respectively. Southern blot analysis did not reveal an increase in gene copies encoding cripto either in cancer or in CP. These findings indicate that cripto expression may contribute to disease progression in pancreatic cancer, and implicate cripto in the histopathological alterations that occur in the pancreas both in cancer and in CP.
Original papers in pharmaceutical analysis (1973)

W. F. Smyth, T. D. White and P. I. Harrison, Proc. Soc. Anal. Chem., 1973, 10, 9 DOI: 10.1039/SA9731000009
<title>Efficient convolution algorithm for VLIW media processors</title> (1998)

Convolution is widely used as an effective tool for enhancing image features, such as points, lines, or edges, and smoothing noise. One major challenge in implementing convolution in real time has been its large computational requirement. For example, convolving a 512 X 512 image with a 7 X 7 kernel requires 50 million operations. Therefore, to achieve the computational performance needed in real-time applications, hardwired solutions with ASICs and/or fixed-function chips with little programmability have been used. The disadvantages associated with hardwired implementations are that they are rigid, unifunctional and not upgradable. Our approach has been programmable convolution, which is flexible, multi-functional, easily upgradable and has a performance comparable to the hardwired implementations. This paper describes an efficient algorithm for convolution, which can be implemented in software on the new generation of VLIW mediaprocessors. These processors can perform multiple multiplication, addition and load/store operations in a single instruction, which can be used effectively in convolution to reduce the execution time. We have implemented this algorithm on a new mediaprocessor called the MAP1000<SUP>TM</SUP> where it takes 8.6 ms for the convolution of a 512 X 512 image with a 7 X 7 kernel. This performance is 7 times faster than the previously reported software-based convolution on the Texas Instruments TMS320C80 mediaprocessor and is comparable with the hardwired implementations for the same image and kernel size. This algorithm and its implementation on the next- generation programmable mediaprocessor clearly demonstrate the feasibility of software-based convolution.
In Vitro Interactions of Approved and Novel Drugs against <i>Paecilomyces</i> spp (2004)

We have evaluated the in vitro activity of 15 combinations of antifungal drugs (amphotericin B, itraconazole, voriconazole, albaconazole, ravuconazole, terbinafine, and micafungin) against four isolates of Paecilomyces variotii and three of P. lilacinus. The interaction of terbinafine with the four azoles was synergistic for 53% of the combinations, while the interactions of both amphotericin B and micafungin with the rest of antifungal agents were mainly indifferent.
Fast Detection of Polygons in 3D Point Clouds from Noise-Prone Range Sensors (2007)

3D sensing and modeling is increasingly important for mobile robotics in general and safety, security and rescue robotics (SSRR) in particular. To reduce the data and to allow for efficient processing, e.g., with computational geometry algorithms, it is necessary to extract surface data from 3D point clouds delivered by range sensors. A significant amount of work on this topic exists from the computer graphics community. But the existing work relies on relatively exact point cloud data. As also shown by others, sensors suited for mobile robots are very noise-prone and standard approaches that use local processing on surface normals are doomed to fail. Hence plane fitting has been suggested as solution by the robotics community. Here, a novel approach for this problem is presented. Its main feature is that it is based on region growing and that the underlying mathematics has been re-formulated such that an incremental fit can be done, i.e., the best fit surface does not have to be completely re-computed the moment a new point is investigated in the region growing process. The worst case complexity is O(n log(n)), but as shown in experiments it tends to scale linearly with typical data. Results with real world data from a Swissranger time-of-flight camera are presented where surface polygons are always successfully extracted within about 0.3 sec.
A Comparative Inventory of Metal Transporters in the Green Alga <i>Chlamydomonas reinhardtii</i> and the Red Alga <i>Cyanidioschizon merolae</i>   (2005)

peer reviewed
Note: Moissanite backing plates for use in diamond anvil high pressure cells (2016)

The use of moissanite (single crystal SiC) for backing plates within diamond anvil cells (DACs) has been developed. These have significant technical advantages in certain experiments. For example, moissanite is non-magnetic so is suitable for use in high magnetic fields and for magnetization experiments. Being translucent to light, including x-rays, means that openings are not required in the backing plate and as such has significant mechanical advantages and can provide enhanced scattering angles for x-ray diffraction experiments. The new backing plates have been successfully tested to over 25 GPa using diamond anvils with 0.5 mm culets.
<b>Hydrolytic Cleavage of N-Terminal Peptide Bonds by a Cobalt Chelate</b> (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHydrolytic Cleavage of N-Terminal Peptide Bonds by a Cobalt ChelateJames P. Collman and David A. BuckinghamCite this: J. Am. Chem. Soc. 1963, 85, 19, 3039–3040Publication Date (Print):October 1, 1963Publication History Published online1 May 2002Published inissue 1 October 1963https://pubs.acs.org/doi/10.1021/ja00902a048https://doi.org/10.1021/ja00902a048research-articleACS PublicationsRequest reuse permissionsArticle Views213Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Thienyl methacrylates (1974)

Abstract Thienyl methacrylates have been synthesized and characterized. Thienyl methacrylate has been homo‐ and copolymerized.
An investigation of pectin and pectic acid in dilute aqueous solution (1978)

Abstract Light‐scattering measurements have been carried out on carefully clarified aqueous solutions of pectin and pectic acid. The strong dependence of the inverse excess scattering intensity on angle yields pectin chain dimensions that are inconsistent with the complete molecular dispersion of pectin molecules possessing the degrees of polymerization indicated by the measured osmotic molecular weights. Negligible or negative concertration dependences of the inverse scattering intensities coupled with the centrifugation, filtration, and gel permeation chromatography behavior of the samples likewise suggest nonequilibrium aggregation of the pectin molecules in solution. It is shown that the measured mean polymer chain dimensions can be rationalized in terms of the presence of a very small proportion of aggregated material.
<title>Multiwavelength, wideband, intensity-modulated optical spectrometer for near-infrared spectroscopy and imaging</title> (1993)

Quantitative determination of chromophore concentrations by near infrared spectroscopy (NIRS) is possible by using the differential pathlength of the detected light, measured noninvasively as the mean time delay of the impulse response function of the tissue. Experimentally this information in the time domain is also available in the frequency domain by intensity modulating the input light and sweeping the modulation frequency between zero and infinity. We describe an intensity modulated optical spectrometer which differs from previously described systems in using four different wavelengths, a wideband modulation frequency (1 MHz to 500 MHz), and the simultaneous measurement of three parameters the dc intensity, ac amplitude, and the phase shift. The measured dc intensity in conjunction with the ac phase shift data allows changes in absorption coefficient (and hence chromophore concentration) to be determined more accurately by correcting for real time path length variations. The ac phase shift in combination with the ac modulation depth theoretically allows for the absolute measurement of tissue absorption and scattering coefficient. Preliminary performance figures for the system suggest values of rms noise of 0.0006 OD, 0.0011 rad and 0.0008% for the measured attenuation, ac phase shift and modulation depth. Using a phantom of fixed geometry with known scattering and absorption properties, the ability of the system to reproduce the information content of the impulse response function for a homogeneous phantom is investigated.