gebhart/patrepeval huggingface dataset:
Holographic storage and associative processing of analog and digital data (2002)

Volume holographic memories combine high storage capacity, massive transfer rates due to page-oriented access, and the ability to associatively search the entire data set in a highly parallel way. We have developed an angularly multiplexed volume holographic associative memory for storing and searching alphanumeric database records. The system uses LiNbO/sub 3/:Fe as the storage medium and operates in three modes: a) the recording mode, when data pages are loaded on the spatial light modulator (SLM) and written in the crystal, b) the addressed-based retrieval mode, when a certain page is chosen and retrieved with the reference beam incident on the crystal at a given angle (address), and c) the content-based retrieval mode.
The utilization of fructose by <i>Escherichia coli</i>. Properties of a mutant defective in fructose 1-phosphate kinase activity (1973)

1. The isolation and properties of a mutant of Escherichia coli devoid of fructose 1-phosphate kinase activity are described. 2. This mutant grew in media containing any one of a variety of substances, including hexoses, hexose 6-phosphates, sugar acids and glucogenic substrates, at rates not significantly different from those at which the parent organism grew on these substrates. However, only the parent grew on fructose or fructose 1-phosphate. 3. Fructose and fructose 1-phosphate inhibit the growth of the mutant, but not of its parent, on other carbon sources. 4. Even though not previously exposed to fructose, the mutant took up [(14)C]fructose rapidly but to only a small extent: [(14)C]fructose 1-phosphate was identified as the predominant labelled product. In contrast, the equally rapid but more extensive uptake of [(14)C]fructose by the parent organism required prior growth in the presence of fructose.
Minimally Invasive Parylene Dual-Valved Flow Drainage Shunt for Glaucoma Implant (2009)

A parylene-enabled microvalved shunt implant for glaucoma drainage is presented in this paper. Enabled by the dual-checkvalve operation, this device can physically drain the extra intraocular fluid and regulate the intraocular pressure (IOP) within the normal range (15-20 mmHg). Improved surgical features, in addition to the functional/microfluidic components, such as parylene-tube carrier and anchors, are also incorporated in such device to realize minimally invasive suture-less implantation, suitable for practical in vivo use. With the optimized micromachining and post-fabrication process procedures, the developed implant is the first checkvalved glaucoma drainage device (GDD), which is passive, consumes no additional power, and functions without any circuit involved to pursue its medical application.
Présentation (2003)

Présentation : les nouvelles statistiques sociales. Un article de la revue Sociologie et sociétés (Les chiffres pour le dire. Innovations conceptuelles et méthodologiques en statistiques sociales) diffusée par la plateforme Érudit.
A dual-phase pulse-modulated polar transmitter with high efficiency and linearity using power recycling (2015)

This paper presents a pulse-modulated power-recycling polar transmitter with a dual-phase digital pulsewidth modulation for the 4G long term evolution (LTE) system. This implementation is capable of achieving high linearity and efficiency by recycling the power of residual spurs from pulse modulation. A prototype balanced transmitter system is constructed with commercially available components. Measurements using a 16-QAM 10-MHz bandwidth LTE signal at 836.5 MHz, it achieves 17.3% efficiency improvement at 21-dBm output power level while passing the stringent adjacent channel leakage power ratio requirements without using any calibration or pre-distortion.
Pathogenesis of<i>Staphylococcus</i>in the Rabbit Anterior Chamber (2005)

This study demonstrates that aqueous humor has a potent host defense capability and that S. aureus, but not S. epidermidis, triggers a PLA(2) response in the rabbit anterior chamber that appears to be due to alpha-toxin.
Significance of Lysyl oxidase‑likeï¿½2 gene expression on the epithelial‑mesenchymal status of hepatocellular carcinoma (2018)

In the present study, we investigated the role of lysyl oxidase‑like 2 (LOXL2), the correlation between LOXL2 and epithelial to mesenchymal transition (EMT) and the effects of using β‑aminopropionitrile (BAPN) to inhibit LOXL2 with the aim of reducing tumor progression in hepatocellular carcinoma (HCC). The expression level of LOXL2 was evaluated in HCC and adjacent non‑cancerous tissues using quantitative reverse transcription polymerase chain reaction and clinicopathological analyses. The effects of BAPN on cell proliferation, migration and invasion were investigated in vitro. Additionally, LOXL2 expression was assessed in the culture supernatants of HCC cell lines. Our results revealed that LOXL2 expression was higher in HCC cell lines and tissues. There was a significant correlation between EMT status and LOXL2 levels (P=0.004). BAPN reduced migration and invasion in HCC cells. HCC patients with high levels of LOXL2 expression had relatively shorter disease‑free survival (P=0.009) and overall survival (P=0.035). The expression level of LOXL2 was similar between cell supernatants and HCC cell lines. A multivariate analysis demonstrated that portal vein invasion (P=0.015), venous invasion (P=0.026), serum AFP (α‑fetoprotein) levels (P=0.019) and LOXL2 expression (P=0.009) were independent prognostic factors. Our results indicated that a higher level of LOXL2 may contribute to tumor progression, indicating that LOXL2 has clinical value as a therapeutic target in HCC.
Visual Discomfort and Visual Fatigue of Stereoscopic Displays: A Review (2009)

Visual discomfort has been the subject of considerable research in relation to stereoscopic and autostereoscopic displays. In this paper, the importance of various causes and aspects of visual discomfort is clarified. When disparity values do not surpass a limit of 1°, which still provides sufficient range to allow satisfactory depth perception in stereoscopic television, classical determinants such as excessive binocular parallax and accommodation-vergence conflict appear to be of minor importance. Visual discomfort, however, may still occur within this limit and we believe the following factors to be the most pertinent in contributing to this: (1) temporally changing demand of accommodation-vergence linkage, e.g., by fast motion in depth; (2) three-dimensional artifacts resulting from insufficient depth information in the incoming data signal yielding spatial and temporal inconsistencies; and (3) unnatural blur. In order to adequately characterize and understand visual discomfort, multiple types of measurements, both objective and subjective, are required.
Challenges in Shallow Water CSEM Surveying: A Case History From Southeast Asia (2007)

CSEM survey in marginal water depths and complex<br>geological setups poses several challenges due to the<br>interference of airwave with electromagnetic field and the<br>background resistivity variations. Recently, PETRONAS<br>conducted a pilot marine CSEM survey in Southeast Asia in<br>relatively shallow water depths. We present here the<br>challenges encountered and the methodology adopted in<br>analysis of CSEM data and the value addition achieved<br>through the survey.
Novel [(diazomethyl)carbonyl]-1,2,3,4-tetrahydronaphthalene derivatives as potential photoaffinity ligands for the 5-HT1A receptor (1990)

The photolabile (diazomethyl)carbonyl function was introduced into the 8-position of 2-(N,N-di-n-propyl-amino)-1,2,3,4-tetrahydronaphthalene in three ways, resulting in the ether 8-[[(diazomethyl)carbonyl]methoxy]-2-(N,N-di-n-propylamino)-1,2,3,4- tetrahydronaphthalene (2), the ester 8-(diazoacetoxy)-2-(N,N-di-n-propyl-amino)-1,2,3,4- tetrahydronaphthalene (3), and the ketone 8-[(diazomethyl)carbonyl]-2-(N,N-di-n-propylamino)- 1,2,3,4-tetrahydronaphthalene (4). Specific binding of these compounds at the 5-hydroxytryptamine1A sites in rat brain membranes labeled with 1 nM [3H]-8-hydroxy-2-(N,N-di-n-propylamino)- 1,2,3,4-tetrahydronaphthalene (8-OH-DPAT) showed IC50 values of ca. 75, 125, and 25 nM, respectively, for the three compounds. Photolysis of methanolic solutions of 2-4 in the absence of receptor proteins lead in each case to an abundance of Wolff-rearranged products. In the case of ether 2, subsequent beta-elimination to 8-OH-DPAT removed this compound from serious consideration as a photoaffinity ligand. Ester 3 and ketone 4 were photolysed in vitro. Whereas ester 3 was ineffective in decreasing the specific binding of [3H]-8-OH-DPAT, ketone 4 decreased 40% of the specific binding of [3H]-8-OH-DPAT in the presence (but not the absence) of ultraviolet light. Thus this ketone emerges from these studies as a good candidate for a photoaffinity label for the 5-hydroxytrypatamine1A receptor.
Modern Crop Protection Compounds (2007)

VOLUME 1: HERBICIDES HRAC, Classification of Herbicides and Resistance Development Acetohydroxyacid Synthase Inhibitors (AHAA / ALS) Protoporphyrinogen-IX-Oxidase-Inhibitors Herbicides with Bleaching Properties New Auxin Mimics as Herbicides Herbicides Disturbing the Synthesis of Very Long Fatty Acids Inhibitors of Cellulose Biosynthesis Safeners for Herbicides Genetically Modified Herbicide Resistant Crops Acetyl-CoA Carboxylase Inhibitors Photosynthesis Inhibitors: Regulatory Aspects, Reregistration in Europe, Market Trends and New Products New Aspects of Plant Regulators VOLUME 2: FUNGICIDES FRAC Mode of Action Classification and Resistance Risk of Fungicides Fungicides Acting on Oxidative Phosphorylation Fungicides Acting on Amino Acids and Protein Synthesis Fungicides Acting on Signal Transduction Fungicides Acting on Cell Division Sterol Biosynthesis Inhibitors Carboxylic Acid Amide (CAA) Fungicides Fluopicolide, A New Oomycetes Fungicide Inducing Perturbation of the Cytoskeleton Melanin Synthesis in Cell Wall Fungicides with Unknown Mode of Action Recently Introduced Powdery Mildew Fungicides Newst Aspects of Nucleic Acid Synthesis Inhibitors - Metalaxyl-M Host Defence Inducers VOLUME 3: INSECTICIDES IRAC, Insectile Resistance and Mode of Action Classification of Insecticides Insect Molting and Metamorphosis Chitin Synthesis Midgut - Transgenic Crops Expressing Bacillus Thuringiensis Cry Proteins Metabolic Processes Nervous System New Unknown Mode of Action Insecticides Affecting Calcium Homeostasis
SNR-dependent coherence weighting for minimum variance beamforming (2011)

Coherence factor (CF) is used to suppress sidelobes and to enhance contrast in ultrasound imaging. Recent research also introduces minimum-variance-distortionless-response (MVDR) based CF (CF <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">mvdr</inf> ) to achieve good resolution for high frame rate application. However, increasing frame rate by unfocused beams reduces signal-to-noise-ratio (SNR). CF-based weighting is susceptible to noise, which underestimates the acoustic strength and lowers the contrast supposed to provide. Wiener postfilter, with worse performance on noise reduction but better robustness, can be combined with CF by scaling the noise power. Hence, CF weighting can be modified so as to avoid the noise effect with the knowledge of local SNR. The proposed method is specifically applied to the high frame rate imaging that has synthetic transmit aperture (STA) and MVDR beamformer. Before finding the MVDR solution, the channel data are used to estimate SNR, which then determines the noise power weighting by a sigmoid function and modifies the CF value. Specifically, at mainlobe with relatively high SNR, the CF or the CF <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">mvdr</inf> is adjusted by lowering its noise weighting. For the region requiring higher resolution, MVDR beamformer can retain its performance. Thus, the contrast can be restored when the noise level is high. Simulations were performed by a 128-element linear array with central frequency 4.37 MHz. The pulse-echo data were generated through STA method with eight subgroups. When the channel has SNR −10 dB, the CR and the CNR by original CF/CF <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">mvdr</inf> were 39.01/34.71 dB and 2.00/1.74 respectively. After modified by SNR, the CR and the CNR were improved to 47.45/47.82 dB and 2.26/2.14 in scaled CF/CF <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">mvdr</inf> cases. Simulations for point pairs was also included to confirm the ability to maintain resolution. In summary, a robust method designed for low SNR cases is proposed.
Mechanism-Based Small Molecule Probes for Labeling CD38 on Live Cells (2009)

CD38 is a type II transmembrane glycoprotein with multiple functions. It acts as an ecto-enzyme as well as a receptor. The enzymatic activity catalyzes the formation of two potent Ca(2+) releasing agents: cyclic adenosine diphosphate ribose (cADPR) from nicotinamide adenine dinucleotide (NAD) and nicotinic acid adenine dinucleotide phosphate (NAADP) from NAD phosphate (NADP). The receptor function of CD38 leads to the phosphorylation of intracellular signaling proteins and the up-regulation of cytokine production in immune cells. These two functions of CD38 underlie its involvement in various biological processes, such as hormone secretion, immune cell differentiation, and immune responses. Clinically, CD38 is used as a negative prognosis marker for chronic lymphatic leukemia (CLL). However, a clear molecular understanding of CD38's role in physiology and pathology is still lacking. To facilitate the study of CD38 at cellular and molecular levels, here we report a mechanism-based method for fluorescently labeling CD38 on live cells. This labeling method does not interfere with the receptor function of CD38 and the downstream signaling. The labeling method is thus a useful tool to study the receptor function of CD38 in live cells. In addition, since the mechanism-based labeling also inhibits the enzymatic activity of CD38, it should be useful for dissecting the receptor function of CD38 without interference from its enzyme function in complicated biological processes.
Space-efficient approximate Voronoi diagrams (2002)

(MATH) Given a set $S$ of $n$ points in $\IR^d$, a {\em $(t,\epsilon)$-approximate Voronoi diagram (AVD)} is a partition of space into constant complexity cells, where each cell $c$ is associated with $t$ representative points of $S$, such that for any point in $c$, one of the associated representatives approximates the nearest neighbor to within a factor of $(1+\epsilon)$. Like the Voronoi diagram, this structure defines a spatial subdivision. It also has the desirable properties of being easy to construct and providing a simple and practical data structure for answering approximate nearest neighbor queries. The goal is to minimize the number and complexity of the cells in the AVD.(MATH) We assume that the dimension $d$ is fixed. Given a real parameter $\gamma$, where $2 \le \gamma \le 1/\epsilon$, we show that it is possible to construct a $(t,\epsilon)$-AVD consisting of \[O(n \epsilon^{\frac{d-1}{2}} \gamma^{\frac{3(d-1)}{2}} \log \gamma) \] cells for $t = O(1/(\epsilon \gamma)^{(d-1)/2})$. This yields a data structure of $O(n \gamma^{d-1} \log \gamma)$ space (including the space for representatives) that can answer $\epsilon$-NN queries in time $O(\log(n \gamma) + 1/(\epsilon \gamma)^{(d-1)/2})$. (Hidden constants may depend exponentially on $d$, but do not depend on $\epsilon$ or $\gamma$).(MATH) In the case $\gamma = 1/\epsilon$, we show that the additional $\log \gamma$ factor in space can be avoided, and so we have a data structure that answers $\epsilon$-approximate nearest neighbor queries in time $O(\log (n/\epsilon))$ with space $O(n/\epsilon^{d-1})$, improving upon the best known space bounds for this query time. In the case $\gamma = 2$, we have a data structure that can answer approximate nearest neighbor queries in $O(\log n + 1/\epsilon^{(d-1)/2})$ time using optimal $O(n)$ space. This dramatically improves the previous best space bound for this query time by a factor of $O(1/\epsilon^{(d-1)/2})$.(MATH) We also provide lower bounds on the worst-case number of cells assuming that cells are axis-aligned rectangles of bounded aspect ratio. In the important extreme cases $\gamma \in \{2, 1/\epsilon\}$, our lower bounds match our upper bounds asymptotically. For intermediate values of $\gamma$ we show that our upper bounds are within a factor of $O((1/\epsilon)^{(d-1)/2}\log \gamma)$ of the lower bound.
Ocular Counter-rolling during Active Head Tilting in Humans (1987)

Human ocular counter-rolling has been measured by means of an infra-red video based system: EMIRAT. This method of three-dimensional eye angular displacement recording has an overall precision of 0.5o, is calibrated and is completely non-invasive. Dynamic counter-rolling gain is about 0.5, increasing with head roll oscillation frequency from 0.3 at 0.1 Hz, lo 0.7 at 1 Hz. Otolithic contribution to this reflex has been taken into consideration.
Separation and characterization of Leydig cells and macrophages from rat testes (1991)

A method involving centrifugal elutriation followed by density gradient centrifugation and incubation with a macrophage monoclonal antibody has been investigated to separate and characterize Leydig cells and macrophages from adult rat testes. After dispersion of the testes with collagenase, the isolated interstitial cells were found to contain 18% Leydig cells and 12% macrophages. These cells were then separated by centrifugal elutriation into eight fractions (F1-F8) (9 to 74 ml/min at 386 g). Each of these fractions was then further purified by density gradient centrifugation on 0-90% Percoll gradients. After centrifugal elutriation, the macrophages were mainly eluted in the first three fractions (F1-F3), whereas the Leydig cell percentage increased in each fraction with increasing flow rate. After further purification of each fraction on Percoll gradients, high percentages of macrophages (11-20%) were found in fractions F1-F3 (average density 1.045 g/ml), containing 11-37% Leydig cells. Less than 3% of the cells in fraction F4-F8 (average density 1.075 g/ml) were macrophages and more than 95% were Leydig cells. Heterogeneity of Leydig cells with respect to sedimentation velocities and function was found. Leydig cells from elutriated- and Percoll-purified fractions F4-F8 were heterogeneous with respect to testosterone and cyclic AMP (cAMP) production but showed a similar binding capacity for 125I-labelled human chorionic gonadotrophin. Leydig cells with the highest sedimentation velocity (35.7 mm/h.g) from fractions F7 and F8 were approximately twofold more responsive to LH (3.3 nmol/l) with respect to testosterone and cAMP production compared with Leydig cells with the lowest sedimentation velocity (20.7 mm/h.g).(ABSTRACT TRUNCATED AT 250 WORDS)
A New Non-Contact Method to Measure Temperature of the Surface of Semiconductor Wafers (1986)

A new direct and non-contact method to determine temperature of the surface of semiconductors by measurements of the refractive index using reflection ellipsometry is proposed. Use of a probing light larger than band gap in energy enhances the change of the refractive index, so that the temperature dependence of the index can be expressed by a simpie formula. Experimental results are in good agreement with the calculations. A temperature resolution of 0.3°C is expected with an ellipsometer resolving to the fourth decimal.
A transgene insertion creating a heritable chromosome deletion mouse model of Prader-Willi and Angelman syndromes (1999)

Prader-Willi syndrome (PWS) and Angelman syndrome (AS) result from the loss of function of imprinted genes in human chromosome 15q11-q13. The central part of mouse chromosome 7 is homologous to human 15q11-q13, with conservation of both gene order and imprinted features. We report here the characterization of a transgene insertion (Epstein-Barr virus Latent Membrane Protein 2A, LMP2A) into mouse chromosome 7C, which has resulted in mouse models for PWS and AS dependent on the sex of the transmitting parent. Epigenotype (allelic expression and DNA methylation) and fluorescence in situ hybridization analyses indicate that the transgene-induced mutation has generated a complete deletion of the PWS/AS-homologous region but has not deleted flanking loci. Because the intact chromosome 7, opposite the deleted homolog, maintains the correct imprint in somatic cells of PWS and AS mice and establishes the correct imprint in male and female germ cells of AS mice, homologous association and replication asynchrony are not part of the imprinting mechanism. This heritable-deletion mouse model will be particularly useful for the identification of the etiological genes and mechanisms, phenotypic basis, and investigation of therapeutic approaches for PWS.
Design and implementation of search engine on distributed network resources (2010)

Through the research and analysis of search requests to the shared resource on the network, we have designed and implemented a distributed resource search engine that can achieve the following functions: when users search resources on Web, they need only log on a single server and can retrieve the resources exists on multiple servers. Article discusses the background of system design, the main functions of software, getting the state of the server, optimum word segment searching, XML data mode of operation in more detail. System simplifies the process of retrieval of resources, and improves the retrieval efficiency.
<b>Inflammation As A Key Event In The Development Of Neointima Following Vascular Balloon Injury</b> (2001)

1. The present review discusses the current evidence to implicate leucocytes as key players in the development of neointima in arteries that have been subjected to balloon angioplasty injury. 2. There is substantial clinical evidence that leucocytes are activated after angioplasty, as determined by increased plasma levels of both leucocyte granulation products and soluble leucocyte and endothelial cell adhesion molecules. 3. Experimental evidence to implicate leucocytes in neointimal formation comes from studies that demonstrate leucocyte accumulation occurs within the vascular wall soon after injury and that induction of leukopenia prevents neointimal formation. 4. The evidence implicating specific adhesion molecules and cytokines in the key events leading to neointimal formation is discussed.
Assisted reproductive technology surveillance - United States, 2004. (2007)

ART-related multiple births represent a sizable proportion of all multiple births nationwide and in selected states. To minimize the adverse maternal and child health effects that are associated with multiple pregnancies, ongoing efforts to limit the number of embryos transferred in each ART procedure should be continued and strengthened. Adverse maternal and infant outcomes (e.g., low birthweight and preterm delivery) associated with ART treatment choices should be explained fully when counseling patients who are considering ART.
1Tb/s (111Gb/s/ch &#x00D7; 10ch) no-guard-interval CO-OFDM transmission over 2100 km DSF (2008)

We demonstrated spectrally efficient (2-b/s/Hz) 1Tb/s DWDM transmission of 111 Gb/s no-guard-interval PDM CO-OFDM signals over DSFs with 50 GHz spacing. The record transmission distance of 2100 km in the 100-Gb/s-data-rate CO-OFDM systems was achieved.