gebhart/patrepeval huggingface dataset:
Development of Advanced Interspecific-bridge Lines among Cucurbita pepo, C. maxima, and C. moschata (2012)

Interspecific hybridization among the three most economically important cultivated species of Cucurbita spp., Cucurbita pepo , C. moschata, and C. maxima can be made but not readily. By means of various pollination measures, different mating systems, and varying selection methods, nine advanced interspecific-bridge lines were developed, in which the crossing barrier among the species and the male sterility of the F 1 and subsequent generations were overcome over a 12-year period from 1999 through 2011. Despite the considerable influence of parental cultigens and environmental factors on the incompatibility of interspecific crosses, the plant and population compatibility significantly increased when a backcross with a recurrent parent in the same species or a multiple-way cross with a parent in the different species was made. As the generations advanced, the percentage of fertile seeds (PFS) significantly increased in all the sib- and self-families. The four advanced interspecific-bridge lines out of nine not only have gained the normal crossability of interspecific hybridization, but also could eliminate the sexual obstacles of the subsequent generations. The results demonstrate that a two- or three-species bridge line with crossing compatibility can be created by two- or three-species recombination and continuous selection. More importantly, the breakthrough of the advanced interspecific-bridge lines could provide a powerful platform for breeders to transfer favorable traits freely among the species and create more valuable and unique types or varieties through a conventional breeding process.
Obtention de plantes haploïdes par culture <i>in vitro</i> d'ovaires et d'ovules non fécondés de tournesol (Helianthus annuus L.) (1987)

Des plantes gynogenetiques ont ete obtenues par culture in vitro d'ovaires et d'ovules de tournesol non fecondes, avec une frequence moyenne de cinq plantes pour mille ovaires. Les embryons ou les cals gynogenetiques issus du sac embryonnaire ont ete inities sur un milieu d'induction comportant le milieu de base de Murashige & Skoog complete avec 2 p.p.m. d'ANA et 10 p. 100 de saccharose. Les taux de regeneration observes varient selon les genotypes, et les plantes regenerees representent en moyenne 47 p. 100 des developpements gynogenetiques obtenus. Le comptage chromosomique des meristemes racinaires des plantes gynogenetiques a mis en evidence que la majorite des plantes obtenues est haploide, et que le reste des plantes est diploide ou mixoploide (2n+n). [...]
Capacity of measured ricean and rayleigh indoor MIMO channels at 2.4 GHz with polarization and spatial diversity (2006)

In this paper, we analyze the impact of polarization diversity on the capacity of multiple-input multiple-output (MIMO) channels in indoor environments. A channel measurement campaign was conducted at 2.4 GHz to measure the co-polarized and cross-polarized subchannels under line-of-sight (LOS) and non-line-of-sight (NLOS) channel conditions. We analyze the measured data in terms of Ricean K-factor, cross-polar discrimination (XPD) and subchannel correlations. A major contribution of this paper is that in these measured channels, we observe a coincidence of low K factors and high XPD. In such channels, MIMO systems employing polarization diversity incur SNR and diversity deficits, when compared to spatial configurations. On the other hand, our results indicate that polarization diversity can substantially lower the subchannel correlations for compact configurations, even in a LOS scenario. We draw a fair comparison in terms of capacity, between spatial MIMO configurations and systems using polarization diversity. We analyze the performance of 2times2 and 4times4 MIMO configurations for a range of values of inter-element spacing
The Application of Low-Valent Titanium Reagents in Organic Synthesis (1989)

The number and variety of applications of low-valent titanium reagents has expanded greatly since their initial use in 1973. This review examines the preparation of low-valent titanium reagents and their development as reagents for inter- and intramolccular coupling, reductive elimination and alkylidenation, with reference to aspects of the mechanism and stereoselectivity. 1. Introduction 2. Low-Valent Titanium Reagents 2.1. Preparation 2.2. Mechanism and Stereoselectivity 3. Intermolecular Coupling of Aldehydes and Ketones 3.1. Preparation of Alkenes 3.1.1. Preparation of Strained Ethylenes 3.1.2. Preparation of Aromatic Olefins 3.1.3. Mixed Coupling of Carbonyl Groups 3.1.4. Scope and Limitation of the Coupling Reaction 3.1.5. Selective Coupling of Ketones and Aldehydes 3.1.5.1. Groups with Large Reduction Potentials 3.1.5.2. Groups with Low Reduction Potentials 3.2. Preparation of Glycols 3.2.1. Mixed Coupling of Carbonyl Compounds 4. Intramolecular Couplings of Carbonyl Groups 4.1. Preparation of Cycloalkenes and Cyclic Ketones 4.2. Preparation of Cyclic Diols 5. Reductive Eliminations 5.1. Dcoxygenation of Glycols 5.2. Reductive Eliminations of Other Groups 6. Alkylidenation of Carbonyl Groups 6.1. Methylenations 6.2. Alkylidenations 7. Conclusions and Summary
VP6 from porcine rotavirus strain CN86: amino acid sequence divergence with conservation of subgroup II specificity (1995)

A porcine rotavirus strain, CN86, originally isolated from rotavirus-infected piglets in Argentina, has been shown to possess unique characteristics. It was the first animal strain described to be antigenically related to human serotype G1 and the standard counterpart of another porcine strain showing rearrangement of genome segment 11. Owing to these features, molecular characterization of this virus seemed relevant. The gene encoding the major inner capsid protein, VP6, was cloned and its nucleotide sequence was determined. Comparative analysis of the deduced amino acid sequence of CN86 VP6 with those representing the four different subgroups showed that it is more closely related to subgroup II human Wa and porcine Gottfried strains, albeit to a lesser extent than they are to each other. Despite exhibiting sequence divergence, CN86 VP6 has 12 out of the 14 residues expected to be conserved in strains bearing subgroup II specificity. Interestingly, CN86 VP6 shows a high degree of homology with VP6 of porcine strain YM rotavirus which, although being closely related to subgroup II strains, has been serologically characterized as subgroup I. Subgroup II reactivity of CN86 strain, predicted by sequence analysis, was confirmed by ELISA with subgroup-specific monoclonal antibodies. Taken together, our results provide evidence for the existence of a human-pig lineage for rotavirus gene 6.
PACAP38 and PAC1 receptor blockade: a new target for headache? (2018)

Pituitary adenylate cyclase activating polypeptide-38 (PACAP38) is a widely distributed neuropeptide involved in neuroprotection, neurodevelopment, nociception and inflammation. Moreover, PACAP38 is a potent inducer of migraine-like attacks, but the mechanism behind this has not been fully elucidated.Migraine is a neurovascular disorder, recognized as the second most disabling disease. Nevertheless, the antibodies targeting calcitonin gene-related peptide (CGRP) or its receptor are the only prophylactic treatment developed specifically for migraine. These antibodies have displayed positive results in clinical trials, but are not effective for all patients; therefore, new pharmacological targets need to be identified.Due to the ability of PACAP38 to induce migraine-like attacks, its location in structures previously associated with migraine pathophysiology and the 100-fold selectivity for the PAC<sub>1</sub> receptor when compared to VIP, new attention has been drawn to this pathway and its potential role as a novel target for migraine treatment. In accordance with this, antibodies against PACAP38 (ALD 1910) and PAC<sub>1</sub> receptor (AMG 301) are being developed, with AMG 301 already in Phase II clinical trials. No results have been published so far, but in preclinical studies, AMG 301 has shown responses comparable to those observed with triptans. If these antibodies prove to be effective for the treatment of migraine, several considerations should be addressed, for instance, the potential side effects of long-term blockade of the PACAP (receptor) pathway. Moreover, it is important to investigate whether these antibodies will indeed represent a therapeutic advantage for the patients that do not respond the CGRP (receptor)-antibodies.In conclusion, the data presented in this review indicate that PACAP38 and PAC<sub>1</sub> receptor blockade are promising antimigraine therapies, but results from clinical trials are needed in order to confirm their efficacy and side effect profile.
THE SOLUTION OF TITANIC HYDROXIDE IN HYDROGEN PEROXIDE (1935)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE SOLUTION OF TITANIC HYDROXIDE IN HYDROGEN PEROXIDES. Katzoff and R. RosemanCite this: J. Am. Chem. Soc. 1935, 57, 7, 1384Publication Date (Print):July 1, 1935Publication History Published online1 May 2002Published inissue 1 July 1935https://pubs.acs.org/doi/10.1021/ja01310a508https://doi.org/10.1021/ja01310a508research-articleACS PublicationsRequest reuse permissionsArticle Views34Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
All-optical regeneration of multi-wavelength signals (2009)

We discuss our experimental results on 8 times10 Gb/s all-optical 2R regeneration, enabled by the innovative dispersion management scheme in Mamyshev regenerator based on off-center filtering of self-phase-modulation-broadened signal spectrum.
Rodlike Polymer Solution Flow through Fine Pores: Influence of Pore Size on Rheological Behavior (1982)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Guy Chauveteau; Rodlike Polymer Solution Flow through Fine Pores: Influence of Pore Size on Rheological Behavior. J. Rheol. 1 April 1982; 26 (2): 111–142. https://doi.org/10.1122/1.549660 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentThe Society of RheologyJournal of Rheology Search Advanced Search |Citation Search
LONG-TERM FATE OF DISPERSED AND UNDISPERSED CRUDE OIL IN TWO NEARSHORE TEST SPILLS (1983)

ABSTRACT The fate and effects of two nearshore discharges of Murban crude oil at Long Cove, Searsport, Maine in August 1981 were studied following a one-year, pre-spill baseline study of the test areas. An upper and a lower intertidal sampling area within a 60 × 100 meter test plot were exposed to dispersed oil in water resulting from the discharge of 250 gallons of oil pre-mixed with 25 gallons of Corexit 9527 dispersant. Release of treated oil was around high-water slack tide on the surface of the water, with added mixing energy provided by mixing gates deployed by small boats. The maximum water depth over the test areas was 3.5 meters. Untreated crude oil (250 gallons) was released on an ebbing tide within a separate, boomed-off 60 × 100 meter test plot. A third test plot served as an oil-free reference plot. Water samples taken near the surface and near the bottom during and after discharge showed that chemically dispersed oil loses lower boiling hydrocarbons in both the aliphatic and aromatic fractions below n-C17as the droplets diffuse downward. Data are given for sediment samples taken from the test plots 11 months pre-spill and 10 months post-spill. Hydrocarbon analyses of the sediment samples show little incorporation of dispersed oil into the sediments of the treated oil plot relative to the sediments exposed to undispersed oil.
Novel Retinoic Acid Receptor-  Transcripts in Acute Promyelocytic Leukemia Responsive to All-trans-Retinoic Acid (1990)

Journal Article Novel Retinoic Acid Receptor-α Transcripts in Acute Promyelocytic Leukemia Responsive to All- trans -Retinoic Acid Get access Wilson H. Miller, Jr, Wilson H. Miller, Jr Laboratory of Molecular Medicine, Memorial Sloan-Kettering Cancer Center and the Cornell University Medical CollegeNew York, NY. Search for other works by this author on: Oxford Academic PubMed Google Scholar Raymond P. Warrell, Raymond P. Warrell * Developmental Chemotherapy and Leukemia Services, Memorial Sloan-Kettering Cancer Center and the Cornell University Medical CollegeNew York, NY. * Correspondence to: Raymond P. Warrell, Jr, MD, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021. Search for other works by this author on: Oxford Academic PubMed Google Scholar Stanley R. Frankel, Stanley R. Frankel Department of Medicine, Memorial Sloan-Kettering Cancer Center and the Cornell University Medical CollegeNew York, NY. Search for other works by this author on: Oxford Academic PubMed Google Scholar Ann Jakubowski, Ann Jakubowski Laboratory of Leukocyte Biology, Memorial Sloan-Kettering Cancer Center and the Cornell University Medical CollegeNew York, NY. Search for other works by this author on: Oxford Academic PubMed Google Scholar Janice L. Gabrilove, Janice L. Gabrilove Laboratory of Leukocyte Biology, Memorial Sloan-Kettering Cancer Center and the Cornell University Medical CollegeNew York, NY. Search for other works by this author on: Oxford Academic PubMed Google Scholar Josephia Muindi, Josephia Muindi Laboratory of Clinical Pharmacology, Memorial Sloan-Kettering Cancer Center and the Cornell University Medical CollegeNew York, NY. Search for other works by this author on: Oxford Academic PubMed Google Scholar Ethan Dmitrovsky Ethan Dmitrovsky Laboratory of Molecular Medicine, Memorial Sloan-Kettering Cancer Center and the Cornell University Medical CollegeNew York, NY. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 82, Issue 24, 19 December 1990, Pages 1932–1933, https://doi.org/10.1093/jnci/82.24.1932 Published: 19 December 1990 Article history Received: 16 October 1990 Revision received: 23 October 1990 Accepted: 23 October 1990 Published: 19 December 1990
Biological activity of ionene polymers (1973)

Ionene polymers are polyammonium salts with positive nitrogens in the backbone, resulting from the polycondensation of diamines with dihalides or from the polycondensation of halo amines. The mechanism of formation of ionene polymers of different structures and their biological activity is reviewed. The antimicrobial and antifungal properties are compared with low molecular weight ammonium salts. Ionenes were found to combine with DNA by means of ionic bonds to yield similar complexes to those obtained with polyamines (spermine and spermidine). They also combine with nerve cell receptors and exercise a more powerful and longer duration ganglionic blocking action than their monomeric analogs. The antiheparin activity of ionenes and the thromboresistance of elastomeric ionene heparin coatings is described. The enhanced biological activity of ionenes as compared with low molecular weight compounds is attributed to a cooperative effect of a large number of positive charges on the polymeric chains.
On non-preemptive scheduling of period and sporadic tasks (2002)

A fundamental problem in the theory of real-time scheduling is examined: scheduling a set of periodic or sporadic tasks on a uniprocessor without preemption and without inserted idle time. The authors give a necessary and sufficient set of conditions C for a set of periodic or sporadic tasks to be schedulable for arbitrary release times of the tasks. They show that any set of periodic or sporadic tasks that satisfies C can be scheduled with an earliest-deadline-first (EDF) scheduling algorithm. The authors present the scheduling model, briefly review the literature in real-time scheduling, prove that the non-preemptive EDF algorithm is universal for sets of tasks, whether periodic or sporadic, and demonstrate the absence of a universal algorithm for periodic tasks with specified release times. It is proved that the problem of deciding schedulability of a set of concrete periodic tasks is intractable.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
CTLA4 blockade reduces immature myeloid cells in head and neck squamous cell carcinoma (2016)

Immature myeloid cells such as myeloid-derived suppressor cells (MDSCs) and M2 macrophages play a vital role in the tumor immune escape and tumor progression. Cytotoxic T lymphocyte-associated antigen 4 (CTLA4), as a negative immune checkpoint, is highly expressed in numerous solid tumors. However, precise functions of CTLA4 in head and neck squamous cell carcinoma (HNSCC) have not yet been elucidated. In this study, we demonstrated that the ratio of CD8(+)/CTLA4 can be used as a potential index with a clinical prognostic value for HNSCC. Using immunocompetent transgenic mouse model with spontaneous HNSCC, we directly observed that targeting CTLA4 decreases MDSCs and M2 macrophages and promotes T cell activation in both tumor microenvironment and macro-environment. In all, our study provides direct evidence in vivo and proposes a rationale for CTLA4 inhibition as a future therapeutic strategy in patients with HNSCC.
Lucky Microseconds: A Timing Attack on Amazon's s2n Implementation of TLS. (2015)

s2n is an implementation of the TLS protocol that was released in late June 2015 by Amazon. It is implemented in around 6,000 lines of C99 code. By comparison, OpenSSL needs around 70,000 lines of code to implement the protocol. At the time of its release, Amazon announced that s2n had undergone three external security evaluations and penetration tests. We show that, despite this, s2n — as initially released — was vulnerable to a timing attack in the case of CBC-mode ciphersuites, which could be extended to complete plaintext recovery in some settings. Our attack has two components. The first part is a novel variant of the Lucky 13 attack that works even though protections against Lucky 13 were implemented in s2n. The second part deals with the randomised delays that were put in place in s2n as an additional countermeasure to Lucky 13. Our work highlights the challenges of protecting implementations against sophisticated timing attacks. It also illustrates that standard code audits are insufficient to uncover all cryptographic attack vectors.
Pricing Schemes in Cloud Computing: An Overview (2016)

Cloud Computing is one of the technologies with rapid development in recent years where there is increasing interest in industry and academia. This technology enables many services and resources for end users. With the rise of cloud services number of companies that offer various services in cloud infrastructure is increased, thus creating a competition on prices in the global market. Cloud Computing providers offer more services to their clients ranging from infrastructure as a service (IaaS), platform as a service (PaaS), software as a service (SaaS), storage as a service (STaaS), security as a service (SECaaS), test environment as a service (TEaaS). The purpose of providers is to maximize revenue by their price schemes, while the main goal of customers is to have quality of services (QoS) for a reasonable price. The purpose of this paper is to compare and discuss several models and pricing schemes from different Cloud Computing providers.
Image reconstruction for fan-beam differential phase contrast computed tomography (2008)

Recently, x-ray differential phase contrast computed tomography (DPC-CT) has been experimentally implemented using a conventional tube combined with gratings. Images were reconstructed using a parallel-beam reconstruction formula. However, parallel-beam reconstruction formulae are not applicable when the parallel-beam approximation fails. In this paper, we present a new image reconstruction formula for fan-beam DPC-CT. There are several novel features of the new image reconstruction formula: (i) when the scanning angular range of data acquisition is larger than pi + gamma(m) (gamma(m) is the full fan angle), the entire field of view can be exactly reconstructed; (ii) when the scanning angular range is smaller than pi + gamma(m), a local region of interest (ROI) can be exactly reconstructed; (iii) it enables an exact reconstruction for a local ROI when the projection data are truncated at some view angles; (iv) it enlarges the imaging field of view when the detector is asymmetrically placed. In this last case, the data are truncated from every view angle. Numerical simulations have been conducted to validate the new reconstruction formula.
Rapid Synthesis of Triazole-Modified Resveratrol Analogues via Click Chemistry (2005)

Resveratrol is a phytoalexin able to display an array of biological activities. We decided to replace the double bond with a triazole ring using the archetypical click reaction: the Huisgen [3 + 2] cycloaddition. Seventy-two triazole derivatives were synthesized via a parallel combinatorial approach. Preliminary data suggest that this procedure can lead to the synthesis of compounds that display some, but not all, of resveratrol's actions with increased potency.
Parallel Processing Algorithms for the Optimal Control of Nonlinear Dynamic Systems (1973)

This paper describes the recent development of parallel processing algorithms for solving optimal control problems for nonlinear dynamic systems. Both the deterministic and stochastic cases are considered. The resulting algorithms are applicable to a large range of parallel architecture computers, including Iliac IV, associative processors, and potential designs based on integrated circuit technology.
Beam search and partial traceback in the frame-synchronous two-level algorithm (TLBS) (1993)

The authors present and clarify some aspects of the frame-synchronous TL (two-level) algorithm. It is demonstrated that beam search and partial traceback can be integrated in the TL algorithm (two-level beam search or TLBS) so as to reduce the complexity of the original frame-synchronous TL. With this modification, TLBS decodes continuously and is well suited for word spotting. TLBS then becomes particularly attractive as it offers the potential for optimally solving the N-best decoding problem. The increased complexity of the TL is upper-bounded by the beam-search width and the traceback itself. The new TLBS algorithm behaves like the OP (one-pass) algorithm from a computational point of view. The complexity of TLBS becomes close to that of the OP for small search windows, and the window size is shown to be below two hundred frames (16 ms frame rate).< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>