gebhart/patrepeval huggingface dataset:
Early Stages of Pulsed-Laser Growth of Silicon Microcolumns and Microcones in Air and SF 6 (1999)

Dense arrays of high-aspect-ratio silicon microcolumns and microcones are formed by cumulative nanosecond pulsed excimer laser irradiation of single-crystal silicon in oxidizing atmospheres such as air and SF 6 . Growth of such surface microstructures requires a redeposition model and also involves elements of self-organization. The shape of the microstructures, i.e. straight columns vs steeply sloping cones and connecting walls, is governed by the type and concentration of the oxidizing species, e.g. oxygen vs fluorine. Growth is believed to occur by a �catalyst-free� VLS (vapor-liquid-solid) mechanism that involves repetitive melting of the tips of the columns/cones and deposition there of the ablated flux of Si-containing vapor. Results are presented of a new investigation of how such different final microstructures as microcolumns or microcones joined by walls nucleate and develop. The changes in silicon surface morphology were systematically determined and compared as the number of pulsed KrF (248 nm) laser shots was increased from 25 to several thousand in both air and SF 6 . The experiments in air and SF 6 reveal significant differences in initial surface cracking and pattern formation. Consequently, local protrusions are first produced and column or cone/wall growth is initiated by different processes and at different rates. Differences in the spatial organization of column or cone/wall growth also are apparent.
Amorphous/crystalline silicon heterojunction solar cells with intrinsic buffer layer (2003)

Simple structure TCO/a-Si:H(n)/c-Si(p) heterojunction solar cells with varied emitters are investigated by current-voltage-characteristics (IV), photoluminescence (PL) and ultra violet photo electron spectroscopy (UPS). A confirmed efficiency of 16.2% on flat substrates is reached. Additionally, cells have been prepared with intrinsic a-Si:H(i) buffer layers, in order to passivate the proper pretreated wafers. This passivation results in an enhanced PL signal and UPS measurements indicate a reduced density of defect states in ultra thin a-Si:H(i) compared to a-Si:H(n) layers.
Dislocations and the piezoelectric effect in III-V crystals (1977)

It is shown that 60° and 90° α and β dislocations give rise to piezoelectrically induced charge distributions and electric fields in the surrounding crystal. The general features of the charge distributions are discussed with special references to the relation between the nature of the distributions and the symmetry of the crystal. Finally, it is shown that the dislocation reaction (a0/2)[101̄]+(a0/2)[011]= (a0/2)[110] is self-consistent as regards electrical properties.
Autologous T lymphocytes may specifically recognize leukaemic B cells in patients with chronic lymphocytic leukaemia (2000)

This study analysed a naturally occurring specific cellular immunity against tumour cells in chronic lymphocytic leukaemia (CLL) patients. Five out of eight patients had blood T lymphocytes able to recognize spontaneously and specifically the autologous tumour B cells (proliferation assay). In these five patients, detection of cytokines by real-time reverse transcription polymerase chain reaction (RT-PCR) revealed that granulocyte-macrophage colony-stimulating factor (GM-CSF) was the most abundant cytokine gene expressed by the T cells that recognized the autologous tumour B cells. Other activated cytokine genes were gamma-interferon (IFN), interleukin (IL)-2 and tumour necrosis factor (TNF)-alpha, but not IL-4. This profile suggests a type 1 anti-B-CLL T-cell response. CD80 and CD54 were relatively downregulated on the native tumour B cells compared with control normal B cells. Upregulation of CD80 on the leukaemic cells was mandatory for the induction of such a specific T-cell response. CD80 and CD54 monoclonal antibodies inhibited the specific T-cell DNA synthesis proliferation. The proliferative T-cell response was either MHC class I or class II restricted (inhibition by monoclonal antibodies). The specific cytokine gene expression could be found in isolated CD4, as well as CD8, T-cell subsets. This study demonstrated the presence of a potential natural specific CD4, as well as a CD8 type 1 T-cell immunity against the leukaemic CLL tumour B cells in CLL. A further detailed analysis of the spontaneous anti-CLL T-cell immunity is warranted that may facilitate the development of effective anti-tumour vaccines in CLL.
A Plethora of Plasmonics from the Laboratory for Nanophotonics at Rice University (2012)

The study of the surface plasmons of noble metals has emerged as one of the most rapidly growing and dynamic topics in nanoscience. Key advances in the synthesis of noble metal nanoparticles and nanostructures have resulted in a broad variety of structures whose geometries can be controlled systematically at the nanoscale. Arising from these efforts is a new level of insight and understanding regarding the fundamental properties of localized plasmons supported by these structures, and, in particular, the properties of interacting plasmon systems. This additional insight has led to the design of plasmonic systems that support coherent phenomena, such as Fano resonances. A broad range of applications are emerging for these structures: single- nanoparticle and nanogap chemical sensors, low-loss plasmon waveguides, and active plasmonic devices and detectors. Applications in biomedicine that exploit the strong photothermal response of nanoparticle plasmons have developed and advanced into clinical trials. The Laboratory for Nanophotonics at Rice has been home to many of these advances. Here, we showcase a variety of functional plasmonic materials and nanodevices emerging from our individual and collaborative efforts.
Altered Neuronal Response During Rapid Auditory Processing and Its Relation to Phonological Processing in Prereading Children at Familial Risk for Dyslexia (2013)

Developmental dyslexia (DD) is a learning disability affecting 5-17% of children. Although researchers agree that DD is characterized by deficient phonological processing (PP), its cause is debated. It has been suggested that altered rapid auditory processing (RAP) may lead to deficient PP in DD and studies have shown deficient RAP in individuals with DD. Functional neuroimaging (fMRI) studies have implicated hypoactivations in left prefrontal brain regions during RAP in individuals with DD. When and how these neuronal alterations evolve remains unknown. In this article, we investigate functional networks during RAP in 28 children with (n = 14) and without (n = 14) a familial risk for DD before reading onset (mean: 5.6 years). Results reveal functional alterations in left-hemispheric prefrontal regions during RAP in prereading children at risk for DD, similar to findings in individuals with DD. Furthermore, activation during RAP in left prefrontal regions positively correlates with prereading measures of PP and with neuronal activation during PP in posterior dorsal and ventral brain areas. Our results suggest that neuronal differences during RAP predate reading instruction and thus are not due to experience-dependent brain changes resulting from DD itself and that there is a functional relationship between neuronal networks for RAP and PP within the prereading brain.
Reduction of ringing noise in transform image codingusing simple adaptive filter (1998)

A numerically simple filter for reducing ringing noise in transform coded images is proposed. The filter adapts to the local image characteristics and has been specifically designed to amend the current deblocking filter in H.263. It is shown that by adding the proposed filter both subjective and objective image quality improve.
Retrovirus-induced disease in poultry (1998)

Three species of avian retrovirus cause disease in poultry: the avian leukosis/sarcoma virus (ALSV), reticuloendotheliosis virus (REV), and lymphoproliferative disease virus (LPDV) of turkeys. The ALSV can be classified as slowly transforming viruses, which lack a viral oncogene, and acutely transforming viruses, which possess a viral oncogene. Slowly transforming viruses induce late onset leukoses of the B cell lymphoid, erythroid, and myeloid cell lineages, and other tumors, by viral promoter insertion into the genome of a host cell and activation of a cellular protooncogene. The various acutely transforming leukemia and sarcoma viruses induce leukotic or other tumors rapidly and carry one or anther (sometimes two) viral oncogenes, of which some 15 have been identified. The ALSV fall into six envelope subgroups, A through E, and the recently recognized J subgroup, which induces myeloid leukosis. With the exception of Subgroup E viruses, these viruses spread vertically and horizontally as infectious virions, and are termed exogenous viruses. Subgroup E viruses are usually spread genetically as DNA proviruses (often defective) in host germ cell genome, and are termed endogenous viruses. Several other families of endogenous viruses also exist, one of which, endogenous avian retrovirus (EAV), is related to Subgroup J ALV. Exogenous viruses, and sometimes endogenous viruses, can have detrimental effects on commercially important production traits. Exogenous viruses are currently controlled by virus eradication schemes. Reticuloendotheliosis virus, which lacks a viral oncogene, causes chronic B cell and T-cell lymphomas in chickens, and also chronic lymphomas in turkeys and other species of birds. An acutely transforming variant of REV, Strain T, carries a viral oncogene, and induces reticuloendotheliosis within a few days. In chickens and turkeys, REV spreads vertically and horizontally. No commercial control schemes are operated. In turkeys, LPDV infection has occurred in several countries, where it caused a lymphoproliferative disease of uncertain nature.
Large Volumes of Carbon Dioxide in Sedimentary Basins (1998)

Carbon dioxide (CO2) is encountered in many sedimentary basins around the world in a variety of geological environments (e.g. Southeast Asia, Italy, Eastern Australia). Data on CO2 occurrences almost invariably come from petroleum exploration activities and are limited by operational and commercial constraints. Where CO2 is abundant it is effectively a natural 'pollutant' which reduces the worth of the hydrocarbon gas present by diluting it and increasing production costs. However large volumes of CO2 are rare with the probability of there being >1% CO2 being less than 1
THE CHEMISTRY OF HUMAN SKIN (1939)

1. The electrophoretic activity of particles of human skin in distilled water and different concentrations of salt solutions has been studied. The electrokinetic potential and the charge density were determined and comparisons made with results obtained by electroendosmosis. 2. The electrokinetic potential is ultimately decreased if sufficient salt is added. The order of inhibition is Al > Ca > Ba > K > Na. 3. The lyotrophic series Li > Na > K > Rb and Cl > I > Br express respectively the comparative effect of the monovalent cations and anions upon the electrokinetic potential of the skin. 4. Since both electrophoresis and electroendosmosis are dependent upon the electrokinetic potential, it follows from the results obtained, that the greatest rate of flow through the human skin under the force of an applied electrical current would be given by concentrations of neutral salts between 0.0001 M and 0.0002 M.
Error reduction for the high-contrast regions in phase measuring profilometry (2013)

Phase measuring profilometry is a method for measuring the 3D profile of objects. The method is known for its accuracy and high speed. In real world applications, however, the 3D reconstructions of the high-contrast regions have large measurement errors due to the smoothing effect by digital cameras. In this paper, we model the smoothing as a mathematical smooth mask applying process. Accordingly, we propose a novel de-convolution method specified for recovering the phase in the high-contrast regions. The experimental results demonstrate that, compared with the traditional method, the new method improves the measurement accuracy by 2.5 times in the high-contrast regions.
Neutron study of the crystal structure and vacancy distribution in the superconductor<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Ba</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">YCu</mml:mi></mml:mrow><mml:mrow><mml:mn>3</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">O</mml:mi></mml:mrow><mml:mrow><mml:mn>9</mml:mn><mml:mi mathvariant="normal">−</mml:mi><mml:mi mathvariant="normal">δ</mml:mi></mml:mrow></mml:msub></mml:mrow></mml:math> (1987)

Two samples of the high-temperature superconductor ${\mathrm{Ba}}_{2}$${\mathrm{YCu}}_{3}$${\mathrm{O}}_{9\mathrm{\ensuremath{-}}\mathrm{\ensuremath{\delta}}}$ with \ensuremath{\delta}=2.0 and 2.2 have been studied at room temperature and at 10 K, with the neutron powder diffraction method and profile analysis. The structure of the compound is orthorhombic. The oxygen atoms are located on four sets of sites and not on five sets as reported earlier in x-ray diffraction studies. Of the two sets of copper atoms, one is surrounded by four oxygen atoms at distances 1.9299(4) and 1.9607(4) A\r{}. This arrangement forms a two-dimensional framework of Cu-O atoms that extends indefinitely along the a- and b-axis. A fifth oxygen atom is located at 2.295(3) A\r{} from the copper atom, giving a pyramidal configuration. In the other set, the Cu atoms are also surrounded by four oxygen atoms, with distances 1.9429(1) and 1.846(2) A\r{}. In this case, however, the oxygen atoms form rectangles connected by vertices, and resulting in chains along the b axis. In the compound with \ensuremath{\delta}=2.0 all oxygen sites are fully occupied. When \ensuremath{\delta}=2.2 there are oxygen vacancies, but these are confined to one set of positions only, specifically to the oxygen atoms of the chains, located on the b axis. No detectable change of the structure has been observed between room and low temperature.
Hydrophobic Interactions in a Cyanobacterial Plastocyanin−Cytochrome <i>f</i> Complex (2001)

The complex of the photosynthetic redox partners plastocyanin and cytochrome f from the thermophilic cyanobacterium, Phormidium laminosum, was investigated by nuclear magnetic resonance (NMR). Chemical-shift perturbation analysis of amide proton and nitrogen nuclei implicates the hydrophobic patch and, to a lesser extent, the "eastern face" of plastocyanin in the complex interface. Intermolecular pseudocontact shifts observed in the complex of cadmium-substituted plastocyanin and ferric cytochrome f specifically define the site of interaction to be between the hydrophobic patch of plastocyanin and the heme region of cytochrome f. Rigid-body structure calculations using NMR-derived restraints demonstrate that plastocyanin is oriented in a "head-on" fashion, with the long axis of the molecule perpendicular to the heme plane. Remarkably, the structure and affinity of the complex are independent of ionic strength, indicating that there is little electrostatic interaction. Lowering the pH results in limited reorganization of the complex interface, while the binding affinity is unaffected. Therefore, protonation of the exposed copper ligand, His92, plays only a minor role in the complex. In contrast to other electron-transfer complexes, the plastocyanin-cytochrome f complex from P. laminosum is predominantly controlled by hydrophobic interactions. These findings are discussed in the context of the previously characterized angiosperm complex.
Transcriptional and Functional Studies of <i>Acidithiobacillus ferrooxidans</i> Genes Related to Survival in the Presence of Copper (2009)

The acidophilic Acidithiobacillus ferrooxidans can resist exceptionally high copper (Cu) concentrations. This property is important for its use in biomining processes, where Cu and other metal levels range usually between 15 and 100 mM. To learn about the mechanisms that allow A. ferrooxidans cells to survive in this environment, a bioinformatic search of its genome showed the presence of at least 10 genes that are possibly related to Cu homeostasis. Among them are three genes coding for putative ATPases related to the transport of Cu (A. ferrooxidans copA1 [copA1(Af)], copA2(Af), and copB(Af)), three genes related to a system of the resistance nodulation cell division family involved in the extraction of Cu from the cell (cusA(Af), cusB(Af), and cusC(Af)), and two genes coding for periplasmic chaperones for this metal (cusF(Af) and copC(Af)). The expression of most of these open reading frames was studied by real-time reverse transcriptase PCR using A. ferrooxidans cells adapted for growth in the presence of high concentrations of Cu. The putative A. ferrooxidans Cu resistance determinants were found to be upregulated when this bacterium was exposed to Cu in the range of 5 to 25 mM. These A. ferrooxidans genes conferred to Escherichia coli a greater Cu resistance than wild-type cells, supporting their functionality. The results reported here and previously published data strongly suggest that the high resistance of the extremophilic A. ferrooxidans to Cu may be due to part or all of the following key elements: (i) a wide repertoire of Cu resistance determinants, (ii) the duplication of some of these Cu resistance determinants, (iii) the existence of novel Cu chaperones, and (iv) a polyP-based Cu resistance system.
Interleukin 8 response by bovine mammary epithelial cells to lipopolysaccharide stimulation (1998)

MAC-T cells secrete IL-8 in response to stimulation with LPS in a dose- and time- dependent manner. The results were consistent with our hypothesis that mammary gland epithelial cells can be a source of IL-8 during the early stage of mastitis. Therefore, IL-8 may have a pivotal role in resolving bacterial infections.
Sustained‐Release Verapamil Formulations for Treating Hypertension (1992)

Verapamil, the first calcium-channel blocker to be introduced for clinical use, is a major drug used for the treatment of systemic hypertension. During the past 10 years, the use of verapamil for hypertension has produced a considerable clinical database to support the efficacy and safety of the agent in many patients. Because of its short half-life, verapamil was originally administered 3 to 4 times daily. During the past decade, a sustained-release formulation of verapamil has been marketed in the US. This product allows for once-daily dosing up to 240 mg/d; however, when higher doses are needed, this sustained-release formulation should be administered twice daily. In addition, the medicine should be taken with food to avoid the high peak blood levels of verapamil, which appears to be related to the delivery system. A new pellet-filled capsule formulation of verapamil (Verelan, Lederle, Wayne, NJ and Wyeth-Ayerst, Philadelphia, PA) is available and provides controlled absorption, 24-hour blood pressure control, improved peak-to-trough plasma levels, and once-daily dosing regardless of dosage size. Prolonged-release verapamil can be taken without food.
N-nitrosodialkylamines do not function as substrates for liver monoamine oxidase. (1985)

Since reports in the literature [Rowland, I.R., Lake, B. G. & Gangolli, S. D. (1980) Mutat. Res. 72, 63-72] have implicated hepatic monoamine oxidase (EC 1.4.3.4) in the activation of N-nitrosodialkylamines to mutagens, it is of basic pharmacological and biochemical interest to determine if these compounds could serve as substrates for this enzyme. The dialkylnitrosamines N-nitrosodiethylamine, N-nitrosodimethylamine, and N-nitrosodibenzylamine were tested and found not to be substrates, competitive inhibitors, or irreversible inhibitors of liver monoamine oxidase. Thus, any role for monoamine oxidase participation in the mutagenic activation of these compounds must be subsequent to an initial conversion of these compounds to their respective secondary amines.
Rheology of metallocene‐catalyzed monomodal and bimodal polyethylenes (1999)

Abstract The effect of molecular architecture on the dynamic viscoelastic properties of new metallocene high density polyethylenes has been analyzed. Bimodal molecular weight distribution metallocene polyethylenes show features different from conventional polydisperse and bimodal polyethylenes. Higher values of Newtonian viscosity (η o ) at the same values of weight average molecular weight ( M w ) and stronger frequency dependence of dynamic viscosity (η′) than in conventional HDPE‐s have been observed; this leads to lower values of the characteristic frequency for the onset of non‐Newtonian behavior (ω o ) and higher values of the power law index (α). These features are probably due to the presence of very small amounts of long chain branching (LCB). The implications of these results in polymer processing are analyzed comparing extrusion rheometer data, which leads to the conclusion that extrusion difficulties in metallocene catalyzed polyethylenes can be overcome with bimodal molecular weight distributions.
A Novel Zinc-Binding Domain Is Essential for Formation of the Functional Junin Virus Envelope Glycoprotein Complex (2007)

The envelope glycoprotein of the Junín arenavirus (GP-C) mediates entry into target cells through a pH-dependent membrane fusion mechanism. Unlike other class I viral fusion proteins, the mature GP-C complex retains a cleaved, 58-amino-acid signal peptide (SSP) as an essential subunit, required both for trafficking of GP-C to the cell surface and for the activation of membrane fusion. SSP has been shown to associate noncovalently in GP-C via the cytoplasmic domain (CTD) of the transmembrane fusion subunit G2. In this report we investigate the molecular basis for this intersubunit interaction. We identify an invariant series of six cysteine and histidine residues in the CTD of G2 that is essential for incorporation of SSP in the GP-C complex. Moreover, we show that a CTD peptide fragment containing His-447, His-449, and Cys-455 specifically binds Zn(2+) at subnanomolar concentrations. Together, these results suggest a zinc finger-like domain structure in the CTD of G2. We propose that the remaining residues in the series (His-459, Cys-467, and Cys-469) form an intersubunit zinc-binding center that incorporates Cys-57 of SSP. This unusual motif may act to retain SSP in the GP-C complex and position the ectodomain loop of SSP for its role in modulating membrane fusion activity. The unique tripartite organization of GP-C could provide novel molecular targets for therapeutic intervention in arenaviral disease.