gebhart/patrepeval huggingface dataset:
Substance P increases microvascular permeability via nitric oxide-mediated convective pathways (1995)

The goal of these studies was to examine the effects of substance P, a tachykinin neuropeptide, on pathways of microvascular permeability. Individual frog mesenteric venular capillaries were cannulated, and albumin apparent permeability coefficients (Ps) were determined by quantitative fluorescence microscopy. Ps of albumin (PsAlb) rose from 6.8 +/- 1.8 (SE) cm.s-1.10(7) at control to 22.3 +/- 2.3 cm.s-1.10(7) when substance P (10(-11) M) was perfused. The effect of increased microvessel permeability induced by substance P (10(-11) M) was blocked with the nonpeptide substance P receptor antagonist CP-96,345 and NG-nitro-L-arginine methyl ester (L-NAME), an inhibitor of nitric oxide synthase. PsAlb increased 0.99 cm.s-1.10(7) for every cmH2O increase in microvessel pressure after treatment of the vessel with substance P, demonstrating coupling of albumin flux to transvascular water flow. In conclusion, the mechanism of increased microvessel permeability in response to substance P appears to be the result of receptor-mediated increase in nitric oxide production and formation of water-filled convective pathways presumably located between adjacent endothelial cells.
Hydrides. (1948)

ADVERTISEMENT RETURN TO ISSUEPREVArticleHydrides.Thomas R. P. Gibb Cite this: J. Chem. Educ. 1948, 25, 10, 577Publication Date (Print):October 1, 1948Publication History Received3 August 2009Published online1 October 1948Published inissue 1 October 1948https://doi.org/10.1021/ed025p577RIGHTS & PERMISSIONSArticle Views226Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (4 MB) Get e-Alerts Get e-Alerts
A morphology-based filter structure for edge-enhancing smoothing (2002)

We introduce the value-and-criterion filter structure, a new framework for designing filters based on mathematical morphology. The value-and-criterion filter structure is more flexible than the morphological structure, because it allows linear and nonlinear operations other than just the minimum and maximum to be performed on the data. One particular value-and-criterion filter, the mean of least variance (MLV) filter, finds the mean over the "subwindow" of data with the smallest variance within an overall window. The ability of the MLV filter to smooth noise while preserving and enhancing edges and corners is demonstrated. An example application of the MLV filter in improving the contrast of magnetic resonance images is also shown.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Evidence for a Mitochondrial Impact of Trimetazidine during Cold Ischemia and Reperfusion (2004)

In organ transplantation, ischemia-reperfusion injury (IRI) has been implicated in delayed graft function (DGF) as well as in short- and long-term complications. Using an autotransplant pig kidney model, changes in renal function and morphology were determined after different periods of cold ischemia in kidneys preserved in the University of Wisconsin solution (UW), high-Na(+) version of UW (HEH) or Celsior (CEL) a newly developed high-Na(+) solution, with or without trimetazidine (TMZ). Kidney function was better preserved in CEL, UW and particularly HEH in combination with TMZ, particularly after 48 and 72 h. Mitochondria integrity was improved in TMZ-preserved groups. This study indicates that TMZ is efficiently protective against IRI even after prolonged preservation and in different preservation solutions.
Phenylsilane dehydrocoupling and addition to styrene catalyzed by (R-indenyl)Ni(phosphine)(methyl) complexes (2008)

This report describes the synthesis and characterization of the Ni–Me complexes (R-indenyl)Ni(PR′ 3 )Me (R = 1-i-Pr, 1-SiMe 3 , and 1,3-(SiMe 3 ) 2 ; R′= Me, Ph) and outlines their catalytic reactivities in the dehydrogenative oligomerization of PhSiH 3 and its addition to styrene in the absence of initiators/activators. Observation of higher hydrosilylation activities for PPh 3 -based compounds featuring bulky substituents on the indenyl ligand confirms earlier suggestions that phosphine dissociation is an important component of the catalytic cycle for this reaction. In contrast, oligomerization of PhSiH 3 is more facile with PMe 3 -based precursors and independent of the steric bulk of the indenyl ligand, implying that this reaction does not involve phosphine dissociation. These conclusions are consistent with the variable-temperature 1 H NMR spectra of {1,3,-(SiMe 3 ) 2 -indenyl}Ni(PR′ 3 )Me and various structural parameters observed in the solid-state structures of {1,3,-(SiMe 3 ) 2 -indenyl}Ni(PPh 3 )Me, {1,3,-(SiMe 3 ) 2 -indenyl}Ni(PMe 3 )Cl, and {1-SiMe 3 -indenyl}Ni(PMe 3 )Me.Key words: nickel-indenyl complexes, hydrosilylation, hydrosilane oligomerization.
Complexity feature extraction of radar emitter signals (2003)

Because the intra-pulse modulation laws of radar emitter signals reflect directly on the signal waveform, a novel approach is presented to extract the complexity features (CFs) of radar emitter signals. CFs, including Lempel-Ziv complexity (LZC) and correlation dimension (CD), can measure the complexity and irregularity of radar signals effectively. To show the effectiveness and feasibility of the introduced approach, CFs of 10 typical radar emitter signals are extracted in our experiments. The results demonstrate that the CFs have good characteristics for clustering the same radar signals and separating different radar signals, which indicates that CF can simplify the design procedure of classifiers and greatly heighten the identification accuracy rate of radar emitter signals.
Exploring the Windows 7 Desktop (2009)

This Chapter contains sections titled: Log On and off windows 7 Work with the Start Menu Work with Frequently Used Programs Set the Date and Time Arrange Icons on the Desktop Create a Desktop Shortcut Empty the Recycle Bin Shut Down Your Computer
NMOS contact resistance reduction with selenium implant into NiPt silicide (2012)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation K. V. Rao, F. A. Khaja, C. N. Ni, S. Muthukrishnan, A. Darlark, J. Lei, I. Peidous, A. Brand, T. Henry, N. Variam, Y. Erokhin; NMOS contact resistance reduction with selenium implant into NiPt silicide. AIP Conference Proceedings 6 November 2012; 1496 (1): 46–49. https://doi.org/10.1063/1.4766486 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Methylphenidate for Parkinson Disease Gait Disorders (2012)

Patients with Parkinson disease (PD) who have had bilateral subthalamic deep brain stimulation (DBS) often develop gait disorders that are difficult to
Recursive motion and structure estimation with complete error characterization (2002)

An algorithm that performs recursive estimation of ego-motion and ambient structure from a stream of monocular perspective images of a number of feature points is presented. The algorithm is based on an extended Kalman filter (EKF) that integrates over time the instantaneous motion and structure measurements computed by a two-perspective-views step. The key features of the authors' filter are: global observability of the model, and complete online characterization of the uncertainty of the measurements provided by the two-views step. The filter is thus guaranteed to be well-behaved regardless of the particular motion undergone by the observer. Regions of motion space that do not allow recovery of structure (e.g., pure rotation) may be crossed while maintaining good estimates of structure and motion. Whenever reliable measurements are available they are exploited. The algorithm works well for arbitrary motions with minimal smoothness assumptions and no ad hoc tuning. Simulations are presented that illustrate these characteristics.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Handbook of Dough Fermentations (2003)

General: history and origins of fermented foods - economic growth and potential market of products and foods using fermentations. Theoretical: yeast fermentation lactic and other fermentations fermentation processes of starters interaction ofmicro-organisms in dough fermentations. Production of starters: bakers yeasts, commercial types commercial and retail starters in germany commercial starters in France commercial starters in Spain commercial starters in USA. Application of starters inbaking and food technology: starters in wheat breads and products starters in rye breads and products starters in miscellaneous grain and mixed grain breads and products starters for production of fermented foods nutritional effects of fermentations.
A new graded electrode for forming intimate contact with ferroelectrics (1969)

A method for forming intimate contact with ferroelectrics and other dielectric materials is proposed. The method, involving the use of a "graded" electrode structure, is shown to be very effective for making a stable, intimate contact to ferroelectric bismuth titanate (Bi <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</inf> Ti <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">12</inf> ). In terms of stability, no distortion in the hysteresis pattern of bismuth titanate samples has been observed in more than three years of observation when a graded electrode is used. In terms of the information of an intimate contact, the minimization of various "contact effects" is demonstrated by the marked reduction of observed coercive field strength when a graded electrode (as opposed to a conventional metal electrode) is used. For Bi <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</inf> Ti <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">12</inf> , the graded electrode structure used consists of a thin semiconducting tin dioxide film placed between a metal and the ferroelectric body.
INFLUENCE OF THE ROAD SURFACE ON ROAD SAFETY IN WET CONDITIONS (1973)

THE PROBLEMS OF WATER RUN-OFF FROM ROAD SURFACES, ARISING FROM SUCH FACTORS AS WIND DIRECTION, UNEVENNESS AND RUTS, CAMBER OF THE CARRIAGEWAY AND THE LENGTH OF THE RUN-OFF PATH ARE DISCUSSED. SEVEN DIFFERENT TYPES OF ROAD SURFACE ARE DESCRIBED, WITH THE DIFFERENT METHODS USED TO MEASURE THEIR SKIDDING RESISTANCE AND ROUGHNESS. PROBLEMS OF DETERMINING LIMITS FOR ROAD SKIDDING RESISTANCE ARE DISCUSSED, USING ROAD ACCIDENT STATISTICAL DATA. THE INFLUENCE OF TYRE TREAD DEPTH ON THE LIMIT OF FRICTIONAL CONNECTION IS EXAMINED IN DETAIL. IN THIS CONNECTION RESULTS ARE GIVEN OF DRIVING TESTS ON ROADS WITH DIFFERENT THICKNESSES OF WATER LAYER AND DIFFERENT SURFACES, WITH ILLUSTRATIONS AND RECOMMENDATIONS FOR REGULATIONS. THE TWO DESIRED FEATURES OF ROAD SURFACES OF LONG LIFE AND GOOD SKIDDING RESISTANCE ARE DIAMETRALLY OPPOSED. RESEARCH INTO THE OPTIMISATION OF THESE CONDITIONS IS NOT YET COMPLETED.
A 2.8 GS/s 44.6 mW Time-Interleaved ADC Achieving 50.9 dB SNDR and 3 dB Effective Resolution Bandwidth of 1.5 GHz in 65 nm CMOS (2013)

This paper presents a power- and area-efficient 24-way time-interleaved successive-approximation-register (SAR) analog-to-digital converter (ADC) that achieves 2.8 GS/s and 8.1 ENOB in 65 nm CMOS. To minimize the power and the area, the capacitors in the capacitive DAC are sized to meet the thermal noise requirements rather than the matching requirements, leading to the LSB capacitance of 50 aF. An on-chip digital background calibration is used to calibrate the capacitor mismatches in individual ADC channels, as well as the inter-channel offset, gain and timing mismatches. Measurement results at the 2.8 GS/s sampling rate show that the ADC chip prototype consumes 44.6 mW of power from a 1.2 V supply while achieving peak SNDR of 50.9 dB and retaining SNDR higher than 48.2 dB across the entire first Nyquist zone with a <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex Notation="TeX">$1.8{\rm V} _{{\rm pp}\mathchar"702D {\rm diff}}$</tex> </formula> input signal. The prototype chip occupies an area of 1.03 <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$\,\times\,$</tex></formula> 1.66 <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">${\rm mm}^{2}$</tex></formula> , including the pads and the testing circuits. The figure of merit (FoM) of this ADC, calculated with the minimum SNDR in the first Nyquist zone, is 76 fJ/conversion-step.
Highly efficient techniques for mitigating the effects of multipath propagation in DS-CDMA delay estimation (2005)

Delay estimation in direct-sequence code-division multiple-access (DS-CDMA) systems is necessary for accurate code synchronization and for applications such as mobile phone positioning. Multipath propagation is among the main sources of error in the DS-CDMA delay estimation process, together with multiple access interference and non-line-of-sight (NLOS) propagation. This paper provides a review of main delay estimation techniques, existing in the literature so far, which are able to cope with multipath propagation, together with our novel delay estimation techniques proposed in the context of DS-CDMA systems. The performance of all these techniques is compared through analysis and simulations, considering also their relative computational complexity and required prior information. Starting from the traditional delay locked loops (DLL) and their improved variants, we discuss several recently introduced delay estimation techniques able to cope with multipath propagation. The characterization of these methods is given in a unified framework, suited for both rectangular and root raised cosine pulse shapes. The main focus in the performance comparison of the algorithms is on the closely-spaced multipath scenario, since this situation is the most challenging for achieving diversity gain with low delay spreads and for estimating LOS component with high accuracy in positioning applications.
Dynamic Model Evaluation to Accelerate Distributed Machine Learning (2018)

The increase in the volume and variety of data has increased the reliance of data scientists on shared computational resources, either in-house or obtained via cloud providers, to execute machine learning and artificial intelligence programs. This, in turn, has created challenges of exploiting available resources to execute such "cognitive workloads" quickly and effectively to gather the needed knowledge and data insight. A common challenge in machine learning is knowing when to stop model building. This is often exacerbated in the presence of big data as a trade off between the cost of producing the model (time, volume of training data, resources utilised) and its general performance. Whilst there are many tools and application stacks available to train models over distributed resources, the challenge of knowing when a model is "good enough" or no longer worth pursuing persists. In this paper, we propose a framework for the evaluating the models produced by distributed machine learning algorithms during the training process. This framework integrates with the cluster job scheduler so as to finalise model training under constraints of resource availability or time, or simply because model performance is asymptotic with further training. We present a prototype implementation of this framework using Apache Spark and YARN, and demonstrate the benefits of this approach using sample applications with both supervised and unsupervised learning algorithms.
Organized Motion in Turbulent Flow (1981)

The field of fluid mechanics is rapidly advancing, driven by unprecedented volumes of data from experiments, field measurements, and large-scale simulations at multiple spatiotemporal scales. Machine learning (ML) offers a wealth of techniques to extract ...Read More
Serum Concentrations of Trimethoprim and Sulfadiazine Following Oral Paste Administration to the Horse (1981)

Two fasted and 2 fed horses were dosed orally with a combined trimethoprim and sulfadiazine paste formulation at a dose of 35 mg (1:5 combined active ingredients)/kg. Serum concentrations of each drug were determined periodically for 3 consecutive days for the 4 horses. The extent and rate of absorption for trimethoprim were variable, but peak serum concentrations occurred generally within 3 hours; sulfadiazine absorption was slower, reaching peak concentrations by 6 hours. Fasting did not have a consistent effect on the serum concentration profiles for either drug. Both drugs achieved serum concentrations that equaled or exceeded the minimum inhibitory concentrations necessary to inhibit the growth of certain pathogens common to the horse. Thus, the paste formulation provides an effective means of dose administration of horses.
Endogenous synthesis and enhancement of conjugated linolieic acid in pasture-fed dairy cows (2002)

The primary conjugated linoleic acid (CLA) isomer in milkfat, cis-9, trans-11 CLA, is a proven anticarcinogen in rodents and can be derived directly from ruminal biohydr ogenation of linoleic acid. The major fatty acid in pasture, however, is α‐linolenic acid; the biohydrogenation of which does not produce cis-9, trans-11 CLA as an intermediate. Therefore, in grazing cows, cis-9, trans-11 CLA must be produced by other sources, possibly via ∆ 9 -desaturation of trans-11 vaccenic acid (TVA), a biohydrogenation product of both α‐linolenic acid and linoleic acid. Studies were conducted to i) determine the importance of endogenous synthesis of cis-9, trans-11 CLA in pasture-fed cows and ii) increase the level of cis-9, trans-11 CLA. The first study involved abomasal infusion of sterculic oil (SO) to inhibit the activity of the ∆ 9 -desaturase enzyme. Abomasal infusion of SO decreased the concentration of cis-9, trans-11 CLA in milk fat by 71% (P<0.01; 3.6 c.f. 12.1 ± 0.15 mg/g fatty acid). The presence of cis-9, C 10:1 , cis-9, C 12:1 and cis-9, C 14:1 in the milk fat of cows following SO treatment indicated ∆ 9 -desaturase was not completely inhibited. Using the changes in these fatty acids to evaluate the extent of ∆ 9 -desaturase inhibition with SO treatment, an estimated 87-100% of cis-9, trans-11 CLA in milk fat was of endogenous origin. In the second study, sunflower oil at 4% DMI/cow/day invoked a 38% increase (P<0.01) in milk fat TVA (61.3 c.f. 44.4 ± 0.51 mg/g fatty acid) and a subsequent 28% increase (P<0.01) in cis-9, trans-11 CLA concentrations compared to control (28.5 c.f. 22.3 ± 0.19 mg/g fatty acid). Results demonstrate that endogenous synthesis is the major source of cis-9, trans-11 CLA in pasture-fed dairy cows and levels can be enhanced by increasing the supply of the ruminally-derived precursor, TVA.
Voice and data transmission in a mobile radio channel at 850 MHz (1977)

This paper is a review of those properties of a communications channel in the 850 MHz band that have importance to the quality of voice and data transmission for frequency modulated land mobile radio. The presentation is made with emphasis on the simpler aspects and consequences of the propagation environment encountered. The distribution of fading amplitude and rate and the distribution of fade durations are described such that a qualitative impression is gained of the effect of fades on voice transmission, and a quantitative description is obtained of their effect on data transmission.
Intelligent Data Mining Techniques for Emergency Detection in Wireless Sensor Networks (2016)

2nd IEEE International Conference on Cloud and Big Data Computing (CBDCom 2016), Toulouse, France, 18-21 July
Treatment of Venous Thromboembolism (2014)

The mainstay of VTE treatment is anticoagulation, while interventions such as thrombolysis and inferior vena cava filters are reserved for limited circumstances. Multiple therapeutic modes and options exist for VTE treatment with small but nonetheless important differential effects to consider. Anticoagulants will probably always increase bleeding risk, necessitating tailored treatment strategies that must incorporate etiology, risk, benefit, cost, and patient preference. Although great progress has been made, further study to understand individual patient risks is needed to make ideal treatment decisions.
Superhigh-frequency surface-acoustic-wave transducers using AlN layers grown on SiC substrates (2002)

We demonstrate the operation of surface-acoustic-wave (SAW) transducers fabricated on AlN/SiC structures at frequencies as high as 19 GHz. The high SAW velocity of the AlN film is enhanced by the even higher sound velocity of the SiC substrate, enabling us to achieve these frequencies with a SAW wavelength of 400 nm.
Tissue- and developmental-stage-specific methylation in the two kidney promoters of the rat <i>γ</i>-glutamyl transpeptidase gene (1992)

We have investigated, using DNA methylation patterning, the site-specific methylation of promoters I and II of the rat gamma-glutamyl transpeptidase gene. This analysis was done in fetal, newborn and adult rat kidney, in which promoters I and II are progressively active during development, as well as in rat liver, which never expresses mRNAs from these two promoters. During kidney development, a progressive demethylation occurs in the promoter I and II region, specially at the level of the most proximal MspI site of promoter II. A progressive reorganization of the methylated sites within the 5' end of the gene also occurs during liver development.
Treatment of Refractory Heart Failure with Infusion of Nitroprusside (1974)

Abstract Sodium nitroprusside infused in 18 patients with intractable heart failure (nine with ischemic heart disease and nine with cardiomyopathy) produced a prompt reduction of left ventricular filling pressure (pulmonary wedge or left ventricular end-diastolic pressure) from an average of 32.2 to 17.2 mm Hg and a rise in cardiac output from an average of 2.98 to 5.2 liters per minute. Mean arterial pressure fell by 15 mm Hg, and heart rate was slightly but significantly slowed. Stroke volume and forward ejection fraction were nearly doubled. Responses were similar in ischemic heart disease and cardiomyopathy. A diuresis and natriuresis accompanied the infusion, and the clinical response was sustained in five patients in whom the drug was continued for 24 to 72 hours. These results suggest that intractable heart failure may be effectively treated by reduction in impedance to left ventricular ejection. (N Engl J Med 291:587–592, 1974)