gebhart/patrepeval huggingface dataset:
Supramolecular Pseudorotaxane Polymers from Complementary Pairs of Homoditopic Molecules (2003)

Self-assembly of supramolecular pseudorotaxane polymers from complementary homoditopic building blocks comprised of bis(dibenzo-24-crown-8) esters derived from the hydroxymethyl crown ether and aliphatic diacid chlorides (CxC, x = number of methylene units in the diacid segment) and 1,10-bis[p-(benzylammoniomethyl)phenoxy]alkane bis(hexafluorophosphate)s (AyA, y = number of methylene units in the linker) has been studied. (1)H NMR spectroscopic studies of bis[(2-dibenzo-24-crown-8)methyl] sebacate (C8C) with dibenzylammonium hexafluorophosphate (6) showed that the two binding sites of the ditopic host are equivalent and independent (no positive or negative cooperativity). Likewise the binding sites in 1,10-bis[p-(benzylammoniomethyl)phenoxy]decane bis(hexafluorophosphate) (A10A) were shown to behave independently with dibenzo-24-crown-8 (1a). Then using (1)H NMR spectroscopy on dilute equimolar solutions (<1 mM) of CxC and AyA association constants were estimated for the formation of the linear (lin-CxC*AyA) and cyclic (cyc-CxC*AyA) dimers, thus enabling effective molarities to be estimated for the various systems. Finally (1)H NMR spectroscopy was used to semiquantitatively or qualitatively demonstrate the formation of linear supramolecular polymers lin-[CxC*AyA](n) in more concentrated solutions (up to 2.0 M) of the complementary pairs of CxC and AyA. The sizes of the assemblies (n values) are not as great as the dilute solution studies predict; this is attributed to the deleterious effect of ionic strength and exo complexation at high concentrations. However, as expected from the dilute solution results, linear extension is indeed favored with the longer building blocks, meaning that "monomer" end-to-end distance is a key factor in reducing the amount of cyclic species that form. Viscosity experiments clearly demonstrate the formation of large noncovalent polymers lin-[CxC*AyA](n) in concentrated solutions. Cohesive film and fiber formation also indicate that supramolecular polymers of sufficient size to enable entanglement self-assemble in these solutions.
High reliability Cu interconnection utilizing a low contamination CoWP capping layer (2004)

Copper (Cu) damascene interconnects with a cobalt tungsten phosphorus (CoWP) capping layer were developed using an alkaline-metal-free electrodes plating process without palladium (Pd) catalyst activation. The wafer contamination level after processing is consistent with requirements for present LSI fabrication lines. Within wafer CoWP deposition uniformity is high and interconnects wire resistance increases by less than 5% after deposition. Electromigration (EM) testing shows no failures after two thousand hours and stress induced voiding (SIV) testing shows no failure after three thousand hours. This EM result is a 2 order or magnitude improvement over a non CoWP process.
A Novel Antiandrogen, Compound 30, Suppresses Castration-Resistant and MDV3100-Resistant Prostate Cancer Growth <i>In Vitro</i> and <i>In Vivo</i> (2013)

Resistance to antiandrogen drugs, like MDV3100, occurs in patients with castration-resistant prostate cancer (CRPC). Thus, preventing or treating antiandrogen resistance is a major clinical challenge. We identified a novel antiandrogen, Compound 30, and compared its efficacy with MDV3100. We found that Compound 30 inhibits androgen receptor (AR) activity in LNCaP cells, C4-2 cells, as well as MDV3100-resistant cell lines. Compared with MDV3100, Compound 30 treatment induces greater reduction in AR, prostate-specific antigen (PSA), and AR transcriptional activity, and prevents AR nuclear translocation in AR-sensitive LNCaP cells. Compound 30 has antiproliferative effects in LNCaP cells, in castrate-resistant C4-2 cells, and those resistant to MDV3100. Compound 30 was equally as effective as MDV3100 in reducing tumor volume and PSA in vivo. More importantly, Compound 30 is effective at inhibiting AR activity in MDV3100-resistant cell lines and significantly prevented tumor growth and PSA increases in mice bearing MDV3100-resistant xenografts. Together, our data show that Compound 30 strongly inhibited AR activity and suppressed castration-resistant LNCaP growth as well as MDV3100-resistant cell growth in vitro and in vivo. These data provide a preclinical proof-of-principle that Compound 30 could be a promising next generation anti-AR agent, especially in the context of antiandrogen-resistant tumors.
Systematic Lossy Error Protection based on H.264/AVC redundant slices and flexible macroblock ordering (2006)

The authors propose a scheme for Systematic Lossy Error Protection (SLEP) of an H.264/AVC compressed video bit stream, using standard compatible features such as redundant slices, and flexible macroblock ordering. The systematic portion consists of a conventional H.264/AVC bit stream. For error resilience, an additional Wyner-Ziv bit stream is also transmitted. The Wyner-Ziv bit stream allows the decoding of a coarsely quantized description of the original video signal, and is efficiently generated by using H.264/AVC redundant slices in conjunction with Reed-Solomon coding. The Wyner-Ziv bit stream is decoded in order to recover the redundant video descriptions, which are used in lieu of portions lost from the original video signal due to channel errors. SLEP allows the video quality to degrade gracefully with worsening channel conditions, and provides a flexible trade-off between the achieved error resilience and the coarseness of the redundant description. The performance can be improved especially for low motion video sequences, by applying SLEP to a region-of-interest in the video frame, using flexible macroblock ordering (FMO). Experimental results provided for two video transmission scenarios, demonstrate the advantages of SLEP over forward error correction (FEC) as an error resilience scheme.
Advances in silicon photonics WDM devices (2014)

System performance scaling imposes an increase of package-to-package aggregate bandwidths to interface chips in high performance computing. This scaling is expected to encounter several I/O bottlenecks (pin count, speed, power consumption) when implemented in the electrical domain. Several optical interface technologies are being proposed among which silicon photonics, considered as a promising candidate. In this paper we will review the recent progress made in this technology that may enable multi-channel WDM links for package-to-package interconnects: 1.0V drivers with microring modulators and compact manufacturable microring filters with efficient thermal tuning.
A/Z : from the life of meaning to the meaning of life (2018)

"Zholkovsky’s work—vast in scope and eclectic in methodology—has long been humanizing semiotics in both the Russian and American academy, giving it a face, a sense of humor, a stake in the real worlds we live by, but never losing its structuralist bedrock. The essays collected here, which range from Pushkin to Fyodor Karamazov, Okudzhava and Sedakova, from Peter the Great’s scandals abroad to Russian literary theory and filmmaking at home, are a goldmine by leading Slavists in North America, Europe, and Russia. A huge book of brilliant nuggets, it lights up the contours of our field today while paying perfect vignette-like tribute to Alik’s long non-conformist career, as fascinating and inscrutably flexible as it was often perilous.” (By Caryl Emerson).
A high temperature vacuum annealing method for forming ohmic contacts to GaN and SiC (2002)

In this work we report on the high temperature annealing of Ti/Al and Cr/Al contacts on n-GaN by a vacuum annealing technique. This method consists of annealing the samples on a resistively heated tungsten strip, in vacuum, with an Ar background ambient of 5/spl times/10/sup -5/ Torr. Contact resistivities as low as 2.2/spl times/10/sup -5/ /spl Omega/-cm/sup 2/ and 4.1/spl times/10/sup -5/ /spl Omega/-cm/sup 2/ were obtained for Ti/Al and Cr/Al ohmic contact metallizations respectively. Auger profile analysis showed minimal oxidation of the Al surface in the vacuum annealed samples whereas high levels of O were observed in the furnace annealed case. A contact resistivity of 4.3/spl times/10/sup -4/ /spl Omega/-cm/sup 2/ was achieved for Si/Pt metallization on p-SiC.
ESPRIT-estimation of signal parameters via rotational invariance techniques (1989)

An approach to the general problem of signal parameter estimation is described. The algorithm differs from its predecessor in that a total least-squares rather than a standard least-squares criterion is used. Although discussed in the context of direction-of-arrival estimation, ESPRIT can be applied to a wide variety of problems including accurate detection and estimation of sinusoids in noise. It exploits an underlying rotational invariance among signal subspaces induced by an array of sensors with a translational invariance structure. The technique, when applicable, manifests significant performance and computational advantages over previous algorithms such as MEM, Capon's MLM, and MUSIC.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Mid-Infrared Photoacoustic Detection of Glucose in Human Skin: Towards Non-Invasive Diagnostics (2016)

Diabetes mellitus is a widespread metabolic disease without cure. Great efforts are being made to develop a non-invasive monitoring of the blood glucose level. Various attempts have been made, including a number of non-optical approaches as well as optical techniques involving visible, near- and mid-infrared light. However, no true breakthrough has been achieved so far, i.e., there is no fully non-invasive monitoring device available. Here we present a new study based on mid-infrared spectroscopy and photoacoustic detection. We employ two setups, one with a fiber-coupled photoacoustic (PA) cell and a tunable quantum cascade laser (QCL), and a second setup with two QCLs at different wavelengths combined with PA detection. In both cases, the PA cells are in direct skin contact. The performance is tested with an oral glucose tolerance test. While the first setup often gives reasonable qualitative agreement with ordinary invasive blood glucose measurements, the dual-wavelength approach yields a considerably improved stability and an uncertainty of only ±30 mg/dL of the blood glucose concentration level at a confidence level of 90%. This result is achieved without advanced data treatment such as principal component analysis involving extended wavelength ranges.
WiseNET: An indoor multi-camera multi-space dataset with contextual information and annotations for people detection and tracking (2019)

Nowadays, camera networks are part of our every-day life environments, consequently, they represent a massive source of information for monitoring human activities and to propose new services to the building users. To perform human activity monitoring, people must be detected and the analysis has to be done according to the information relative to the environment and the context. Available multi-camera datasets furnish videos with few (or none) information of the environment where the network was deployed. The proposed dataset provides multi-camera multi-space video sets along with the complete contextual information of the environment. The dataset regroups 11 video sets (composed of 62 single videos) recorded using 6 indoor cameras deployed on multiple spaces. The video sets represent more than 1 h of video footage, include 77 people tracks and captured different human actions such as walking around, standing/sitting, motionless, entering/leaving a space and group merging/splitting. Moreover, each video has been manually and automatically annotated to include people detection and tracking meta-information. The automatic people detection annotations were obtained by using different complexity and robustness detectors, from machine learning to state-of-art deep Convolutional Neural Network (CNN) models. Concerning the contextual information, the Industry Foundation Classes (IFC) file that represents the environment's Building Information Modeling (BIM) data is also provided. The BIM/IFC file describes the complete structure of the environment, it's topology and the elements contained in it. To our knowledge, the WiseNET dataset is the first to provide a set of videos along with the complete information of the environment. The WiseNET dataset is publicly available at https://doi.org/10.4121/uuid:c1fb5962-e939-4c51-bfd5-eac6f2935d44, as well as at the project's website http://wisenet.checksem.fr/#/dataset.
Medieval Ideas of Apocalyptic Mission and the Early Franciscans in Mexico (1989)

On June 18, 1539, at Tlaxcala, New Spain, Indians recently converted to Christianity performed a pageant written and directed by the Franciscan missionaries. The play titled “The Conquest of Jerusalem” featured the final siege of the Holy City led by combined armies from Spain and New Spain aided by forces from France and Hungary. The drama unfolds with the army from New Spain, protected by angels and St. Hippolytus, showing the most valor. Huddled to one side of the battlefield are the Pope and his court offering prayers for a Christian victory. After several attacks, each of which ends in a miracle saving the Christian armies, the Moslems capitulate and convert to the true faith. In the final scene, the Pope causes all the new converts to be baptized after which the Sultan and his soldiers bow before Charles V and proclaim him to be “God's Captain” for all the earth. The pageant commemorated the Truce of Nice concluded on June 17, 1538, between Charles V and Francis I at the urging and coordination of Pope Paul III who wanted to free Charles V to attack the Turks and capture Jerusalem. Celebrating the Truce of Nice was a natural choice for the friars because it reflected commonly held theories of apocalypticism. The pageant exhibited salient themes of the apocalyptic conversion of non-believers and infidels, the recapture of Jerusalem, and the recognition of a “last world ruler.” Toribio de Benavente (Motolinía), who recorded the pageant, prefaced the drama by praying that this prophesied victory would soon happen and he assigned an unprecedented role to the peoples of the New World in the victory.
Implementing One Time Password based security mechanism for securing personal health records in cloud (2014)

Personal Health Record (PHR) is an emerging patient-centric model of health information exchange, which is often outsourced to be stored at a third party, such as cloud providers. Researches had been taken up in enhancing the security of the out sourced PHRs by implementing the Attribute Based Encryption (ABE) to assure the patients control over their PHRs. Yet, most of the attribute based encryption introduces complexity in access control, key management, privacy exposure and scalability of the System. However, the authentication module of the PHR system had been researched less when compared to the security module of the system. In this paper, we propose a "One Time Password" user authentication module along with Advanced Encryption Standard (AES) for encrypting the owners personal Health Record before uploading it onto the semi trusted cloud server.
Growth and surface structure of Ge–Si alloy films on Si(111)-(7×7) (1986)

Thin epitaxial films of a Gex–Si1−x (50-50) alloy for x=0.5 have been grown in ultrahigh vacuum on a Si(111)-(7×7) surface and examined using Auger electron spectroscopy and digital LEED. The alloy films were prepared by thermal evaporation of Ge onto a Si(111) substrate. Following deposition onto a room temperature Si surface, a sequence of (1×1), (5×5), and (7×7) LEED patterns were observed with increasing annealing temperature. The (5×5) structure which forms near 500 °C is indicative of the Ge0.5Si0.5 alloy. Alloy films up to 1000 Å were then grown by Ge deposition onto the Si substrate held at 560 °C where intermixing readily occurs. For film thicknesses greater than two monolayers, the (5×5) surface periodicity of the alloy was always found. The lattice constant of the alloy was determined as a function of film thickness by digital analysis of the LEED patterns using a vidicon camera detector. Results show that for thicknesses less than 150 Å, the Ge–Si alloy grows pseudomorphically on the Si substrate, i.e., the lattice constant of the alloy matches that of the substrate. At thicknesses near 1000 Å, the lattice constant of the surface of the film relaxes to about 1.5% larger than the Si as compared to the value for the bulk Ge0.5Si0.5 alloy which is about 2% larger than Si.
TNF-α-dependent maturation of local dendritic cells is critical for activating the adaptive immune response to virus infection (2001)

Tumor necrosis factor-alpha (TNF-alpha) is well recognized for its role in mediating innate immune responses. However, the mechanisms of TNF-alpha that influence the adaptive immune response to virus infections are not well understood. In this study, we have investigated the role of TNF-alpha in activating the cellular and humoral responses to systemic viral challenge with recombinant replication-defective adenovirus (rAd). Evaluation of T cell function in TNF-alpha-deficient (TNFKO) mice revealed impaired virus-specific proliferation of T cells derived from the draining lymph nodes of the liver. Analysis of dendritic cells (DC) isolated from local draining lymph nodes after systemic challenge showed that DC from TNFKO mice were relatively immature compared with those from strain-matched wild-type mice. In vitro, TNF-alpha was required to mature DC efficiently during virus-mediated stimulation. Adoptive transfer of primed, mature DC into TNFKO mice restored T cell responses and reconstituted anti-adenovirus antibody responses. Thus, TNF-alpha plays a significant role in the maturation of DC after adenovirus challenge both in vitro and in vivo, highlighting the importance of this innate cytokine in activating adaptive immunity to viral challenge.
Analysis of a radial-outflow reaction turbine concept for geothermal application (1978)

The radial-outflow reaction turbine, a pure-reaction turbine designed to improve the conversion efficiency of geothermal energy into electrical power is described. It also has potential as a total-flow turbine for low-temperature water. The principle of incomplete expansion can be used to obtain a reduction in turbine size when the turbine exhausts into a low-pressure condenser. And, by adding this turbine to single- and two-stage flashed-steam systems, the conversion efficiency of systems utilizing low- and high-energy wellhead sources, respectively can be improved. The Appendix outlines the analysis of the radial-outflow reaction turbine and leads to an expression for engine efficiency.
Devic's neuromyelitis optica: A prospective study of seven patients treated with prednisone and azathioprine (1998)

Seven newly diagnosed patients with Devic's neuromyelitis optica were treated with long-term prednisone and azathioprine, and were followed every 2 months for at least 18 months. Their Expanded Disability Status Scale score improved significantly (mean at baseline, 9; mean at 18 months, 3; p < 0.005), and no relapses occurred for more than 18 months. Multicenter controlled studies are needed to prove the efficacy of this therapeutic regimen.
Synthesis of carbocyclic purine nucleosides using key intermediates, carbocyclic AICA-ribosides. (1987)

Treating carbocyclic N1-methoxymethy-inosine and 2'-deoxy-inosine with 1N-NaOH/aq.EtOH gave the carbocyclic 5-amino-4-imidazolecarboxamide-riboside and -2'-deoxyriboside respectively. Reaction of both useful key intermediates with PhCONCS afforded the corresponding 5-(N-isothiocarbamoyl) derivatives in high yield. Methylation of the isothiocarbamoyl groups, followed by treatment with NaOH led to the purine ring-closure (guanine, isoguanine, and xanthosine) reaction.
Soy Peptides and Weight Management (2009)

This chapter contains sections titled: Abstract Introduction Efficacy and Mechanisms of Action of Soy Peptides in Weight Management Food Applications of Soy Peptides for Weight Control Safety of Soy Peptides Information of Global Suppliers Conclusions References
All-optical nonlinear activation function for photonic neural networks [Invited] (2018)

With the recent successes of neural networks (NN) to perform machine-learning tasks, photonic-based NN designs may enable high throughput and low power neuromorphic compute paradigms since they bypass the parasitic charging of capacitive wires.Thus, engineering data-information processors capable of executing NN algorithms with high efficiency is of major importance for applications ranging from pattern recognition to classification.Our hypothesis is therefore, that if the time-limiting electro-optic conversion of current photonic NN designs could be postponed until the very end of the network, then the execution time of the photonic algorithm is simple the delay of the time-of-flight of photons through the NN, which is on the order of picoseconds for integrated photonics.Exploring such all-optical NN, in this work we discuss two independent approaches of implementing the optical perceptron's nonlinear activation function based on nanophotonic structures exhibiting i) induced transparency and ii) reverse saturated absorption.Our results show that the all-optical nonlinearity provides about 3 and 7 dB extinction ratio for the two systems considered, respectively, and classification accuracies of an exemplary MNIST task of 97% and near 100% are found, which rivals that of software based trained NNs, yet with ignored noise in the network.Together with a developed concept for an all-optical perceptron, these findings point to the possibility of realizing pure photonic NNs with potentially unmatched throughput and even energy consumption for next generation information processing hardware.
Organic Matter Mineralization with Reduction of Ferric Iron in Anaerobic Sediments (1986)

The potential for ferric iron reduction with fermentable substrates, fermentation products, and complex organic matter as electron donors was investigated with sediments from freshwater and brackish water sites in the Potomac River Estuary. In enrichments with glucose and hematite, iron reduction was a minor pathway for electron flow, and fermentation products accumulated. The substitution of amorphous ferric oxyhydroxide for hematite in glucose enrichments increased iron reduction 50-fold because the fermentation products could also be metabolized with concomitant iron reduction. Acetate, hydrogen, propionate, butyrate, ethanol, methanol, and trimethylamine stimulated the reduction of amorphous ferric oxyhydroxide in enrichments inoculated with sediments but not in uninoculated or heat-killed controls. The addition of ferric iron inhibited methane production in sediments. The degree of inhibition of methane production by various forms of ferric iron was related to the effectiveness of these ferric compounds as electron acceptors for the metabolism of acetate. The addition of acetate or hydrogen relieved the inhibition of methane production by ferric iron. The decrease of electron equivalents proceeding to methane in sediments supplemented with amorphous ferric oxyhydroxides was compensated for by a corresponding increase of electron equivalents in ferrous iron. These results indicate that iron reduction can outcompete methanogenic food chains for sediment organic matter. Thus, when amorphous ferric oxyhydroxides are available in anaerobic sediments, the transfer of electrons from organic matter to ferric iron can be a major pathway for organic matter decomposition.