gebhart/patrepeval huggingface dataset:
THE PREPARATION OF 1,3-DIAMINO-2-METHYLAMINOPROPANE AND 1,3-DIAMINO-2-AMINOMETHYLPROPANE<sup>1</sup> (1946)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE PREPARATION OF 1,3-DIAMINO-2-METHYLAMINOPROPANE AND 1,3-DIAMINO-2-AMINOMETHYLPROPANE1T. A. GEISSMAN, MAURICE J. SCHLATTER, and IRVING D. WEBBCite this: J. Org. Chem. 1946, 11, 6, 736–740Publication Date (Print):November 1, 1946Publication History Published online1 May 2002Published inissue 1 November 1946https://pubs.acs.org/doi/10.1021/jo01176a014https://doi.org/10.1021/jo01176a014research-articleACS PublicationsRequest reuse permissionsArticle Views310Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Creating entertainment applications for cellular phones (2005)

Cellular phones offer a whole range of interesting and exciting possibilities for entertainment systems coupled with a very resource-constrained environment. In this article we consider the possibilities currently achievable through the example of a networked sports service. Applications that keep users up-to-date with sports results and playing fantasy team games, based on the results of actual events, are well established on the Internet; they attract millions of subscribers world-wide. As yet, the sports results services on cellular phones, even within countries that offer 3G services, are by and large SMS or WAP-based, and there are no dedicated fantasy team game services for cellular phones. In this article we present a novel application using GPRS that not only keeps users up-to-date, wherever they are, with the events of the English Premier Football League, but also provides the opportunity of playing a real-time fantasy football game as these events transpire. As we are seeing moves by cellular phone manufacturers to adopt standardized operating systems, we compare application development in Symbian, Brew, and J2ME. Although J2ME is not an operating system, it has, up until recently, been the only means of cross-platform application development for cellular phonesThis application not only takes advantage of the "nature" of the cellular network, rather than porting existing services off the Internet, but radically improves currently available services in terms of cost and efficiency. It also highlights the fact that resource constraints on a cellular phone are not a bar to creating compelling content. This technique could be applied to a whole range of sports from Formula 1 to baseball.
Serum soluble tumor necrosis factor receptor levels in patients with seasonal allergic rhinitis. (2001)

It is known that several inflammatory cells and cytokines play a role in allergic inflammation. Furthermore, there are seasonal changes in several mediators responsible for allergic inflammation. The aim of this study was to determine seasonal changes in serum concentrations of soluble tumor necrosis factor receptors (sTNFRs) and the relationship with disease activity and other inflammation markers such as eosinophil cationic protein (ECP) in patients with seasonal allergic rhinitis. Serum levels of sTNFRI and sTNFRII were measured before and during the pollen season in 18 patients with seasonal allergic rhinitis and in 17 healthy controls by using commercially available enzyme-linked immunosorbent assay (ELISA) kits. The serum levels of sTNFRI, sTNFRII, IgE, and ECP were significantly higher in patients than those in controls before and during season. sTNFRI, sTNFRII, and IgE levels were higher before season, whereas ECP levels were higher during season. We suggest that sTNFRs might play regulatory roles even in early stages of allergic rhinitis when patients do not have clinical symptoms yet.
F-Formation Detection: Individuating Free-Standing Conversational Groups in Images (2015)

Detection of groups of interacting people is a very interesting and useful task in many modern technologies, with application fields spanning from video-surveillance to social robotics. In this paper we first furnish a rigorous definition of group considering the background of the social sciences: this allows us to specify many kinds of group, so far neglected in the Computer Vision literature. On top of this taxonomy we present a detailed state of the art on the group detection algorithms. Then, as a main contribution, we present a brand new method for the automatic detection of groups in still images, which is based on a graph-cuts framework for clustering individuals; in particular, we are able to codify in a computational sense the sociological definition of F-formation, that is very useful to encode a group having only proxemic information: position and orientation of people. We call the proposed method Graph-Cuts for F-formation (GCFF). We show how GCFF definitely outperforms all the state of the art methods in terms of different accuracy measures (some of them are brand new), demonstrating also a strong robustness to noise and versatility in recognizing groups of various cardinality.
Fast computation of discrete cosine transform through fast Hartley transform (1986)

A relationship between the discrete cosine transform (DCT) and the discrete Hartley transform (DHT) is derived. It leads to a new fast and numerically stable algorithm for the DCT.
Risk of Hemorrhage Associated with Co-Prescriptions for <i>Ginkgo biloba</i> and Antiplatelet or Anticoagulant Drugs (2011)

Although the combination of G. biloba extract with antiplatelet or anticoagulants showed insignificant correlation to the risk of hemorrhage, patients using ginkgo, particularly those with known bleeding risks and elderly, should take a particular attention to the possibility of increasing risk of bleeding.
Superconductivity on the surface of topological insulators and in two-dimensional noncentrosymmetric materials (2010)

We study the superconducting instabilities of a single species of two-dimensional Rashba-Dirac fermions, as it pertains to the surface of a three-dimensional time-reversal symmetric topological band insulator. We also discuss the similarities as well as the differences between this problem and that of superconductivity in two-dimensional time-reversal symmetric noncentrosymmetric materials with spin-orbit interactions. The superconducting order parameter has both $s$-wave and $p$-wave components, even when the superconducting pair potential only transfers either pure singlet or pure triplet pairs of electrons in and out of the condensate, a corollary to the nonconservation of spin due to the spin-orbit coupling. We identify one single superconducting regime in the case of superconductivity in the topological surface states (Rashba-Dirac limit), irrespective of the relative strength between singlet and triplet pair potentials. In contrast, in the Fermi limit relevant to the noncentrosymmetric materials we find two regimes depending on the value of the chemical potential and the relative strength between singlet and triplet potentials. We construct explicitly the Majorana bound states in these regimes. In the single regime for the case of the Rashba-Dirac limit, there exists one and only one Majorana fermion bound to the core of an isolated vortex. In the Fermi limit, there are always an even number (0 or 2 depending on the regime) of Majorana fermions bound to the core of an isolated vortex. In all cases, the vorticity required to bind Majorana fermions is quantized in units of the flux quantum, in contrast to the half flux in the case of two-dimensional ${p}_{x}\ifmmode\pm\else\textpm\fi{}i{p}_{y}$ superconductors that break time-reversal symmetry.
State-of-the-art molecular imaging in esophageal cancer management: implications for diagnosis, prognosis, and treatment. (2015)

Molecular imaging techniques are increasingly being used in addition to standard imaging methods such as endoscopic ultrasound (EUS) and computed tomography (CT) for many cancers including those of the esophagus. In this review, we will discuss the utility of the most widely used molecular imaging technique, (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET). (18)F-FDG PET has a variety of potential applications ranging from improving staging accuracy at the time of initial diagnosis to assisting in radiation target volume delineation. Furthermore, (18)F-FDG PET can be used to evaluate treatment response after completion of neoadjuvant therapy or potentially during neoadjuvant therapy. Finally, we will also discuss other novel molecular imaging techniques that have potential to further improve cancer care.
Development, Characterization, and Validation of a Sensitive Primate-Specific Quantification Assay for Forensic Analysis (2003)

Accurate human-specific DNA quantification is essential for forensic casework analysis. In this work, we describe a microplate-based quantification assay that utilizes the PCR amplification of human-specific TH01 primers. This method enables the reliable quantification of human DNA samples from 0.2 to 40 ng, even in mixtures with nonhuman DNA. Analysis of samples can be semi-automated using 96-well microplates and a spreadsheet-based concentration calculator for high-throughput demands. We have used this quantification method with more than 15,000 forensic samples.
SAW-grade SiO 2 for advanced microfluidic devices (2009)

Acoustoelectronic devices based on surface acoustic wave (SAW) technology are primarily used in radio frequency filters, delay lines, duplexers, amplifiers and RFID tags. Thereby, SAW's are excited at the surface of piezoelectric materials (e.g. Quartz, LiTaO<sub>3</sub>, LiNbO<sub>3</sub>) by an RF signal applied via interdigital transducers (IDTs)<sup>1</sup>. Novel SAW applications that emerged recently in the field of microfluidics such as the handling of minimum quantities of fluids or gases<sup>2,3</sup> require a fluid compatible design approach, high power durability and long lifetime of the devices. However, conventional SAW devices with finger electrodes arranged on top of the chip surface experience acoustomigration damage<sup>4,5</sup> at high power input and/or higher operating temperature leading to failure of the device. Additionally, inappropriate material systems or chip surface topography can limit their performance in microfluidic application. To overcome these limitations the electrodes can be buried in an acoustically suited ("SAW-grade") functional layer which moreover should be adjustable to the specific biotechnological task. Depending on the properties of this layer, it can suppress the acoustomigration impact<sup>6</sup> and improve the power durability of the device. Also, a reduction of the thermally-induced frequency shift is possible<sup>7</sup>. The present paper describes a novel SAW based chip technology approach using a modular concept. Here, the electrodes are buried in surface polished SAW-grade SiO<sub>2</sub> fabricated by means of reactive RF magnetron sputtering from a SiO<sub>2</sub>- target. This approach will be demonstrated for two different metallization systems based on Al or Cu thin films on 128° YX-LiNbO<sub>3</sub> substrates. We also show the application of the SiO<sub>2</sub>-layer with respect to compensation of thermallyinduced frequency shift and bio /chemical surface modification. Investigations were carried out using atomic force microscopy, laser-pulse acoustic measurement, glow-discharge optical emission spectroscopy, spectral reflectometry, variable angle ellipsometry and x-ray photoelectron spectroscopy. The electrode edge covering of sputter deposited SiO<sup>2</sup> layers and the reactive ion etching of the SiO<sub>2</sub> layers are also discussed. This modular technology gives the possibility to improve the compatibility of surface acoustic wave devices to microfluidics and generally allows the integration of SAW driven actuators (pumps and mixing devices) and sensors (sensitive to surface mass change or complex viscosity change) together with other microfluidic elements (e.g. electrophoresis, heating elements) on one chip.
Achieving Better Buying Power for Mobile Open Architecture Software Systems Through Diverse Acquisition Scenarios (2016)

Naval Postgraduate School Acquisition Research Program
Solubility and properties of two crystalline phases of methylene blue (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSolubility and properties of two crystalline phases of methylene blueSamuel W. Bodman, Sidney P. Kodama, Peter C. Pfeil, and Richard Edward StevensCite this: J. Chem. Eng. Data 1967, 12, 4, 500–504Publication Date (Print):October 1, 1967Publication History Published online1 May 2002Published inissue 1 October 1967https://doi.org/10.1021/je60035a010RIGHTS & PERMISSIONSArticle Views570Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alerts Get e-Alerts
Anti-inflammatory effects of Lactobacillus casei BL23 producing or not a manganese-dependant catalase on DSS-induced colitis in mice (2007)

No contribution of MnKat to the protective effect from epithelial damage has been observed in the tested conditions. In contrast, these results confirm the high interest of Lb. casei as an anti-inflammatory probiotic strain.
Wavelets for texture analysis, an overview (1997)

Texture is an important cue for the analysis of many types of images. The term is used to point to intrinsic properties of surfaces, especially those that don't have a smoothly varying intensity. It includes intuitive properties like roughness, granulation and regularity. More formally, texture can be defined as the set of local neighbourhood properties of the gray levels of an image region. Texture analysis is considered a challenging task. The ability to effectively classify and segment images based on textural features is of key importance in scene analysis, medical image analysis, remote sensing and many other application areas.
Integrating VM selection criteria in distributed dynamic VM consolidation using Fuzzy Q-Learning (2013)

Distributed dynamic VM consolidation can be an effective strategy to improve energy efficiency in cloud environments. In general, this strategy can be decomposed into four decision-making tasks: (1) Host overloading detection, (2) VM selection, (3) Host underloading detection, and (4) VM placement. The goal is to consolidate virtual machines dynamically in a way that optimizes the energy-performance tradeoff online. In fact, this goal is achieved when each of the aforementioned decisions are made in an optimized fashion. In this paper we concentrate on the VM selection task and propose a Fuzzy Q-Learning (FQL) technique so as to make optimal decisions to select virtual machines for migration. We validate our approach with the CloudSim toolkit using real world PlanetLab workload. Experimental results show that using FQL yields far better results w.r.t. the energy-performance trade-off in cloud data centers in comparison to state of the art algorithms.
An Efficient Oxidative Lactonization of 1,4-Diols Catalyzed by Cp*Ru(PN) Complexes (2007)

[reaction: see text] An efficient oxidative lactonization of 1,4-diols in acetone is accomplished by the well-defined ruthenium catalyst, whose bifunctional nature underlies the high efficiency as well as unique chemo- and regioselectivity of the reaction which provides a rapid access to gamma-butyrolactones including flavor lactones hinokinin, and muricatacin.
Properties of subcloned subunits of bacterial acetohydroxy acid synthases (1992)

The acetohydroxy acid synthase (AHAS) isozymes from enterobacteria are each composed of a large and small subunit in an alpha 2 beta 2 structure. It has been generally accepted that the large (ca. 60-kDa) subunits are catalytic, while the small ones are regulatory. In order to further characterize the roles of the subunits as well as the nature and the specificities of their interactions, we have constructed plasmids encoding the large or small subunits of isozymes AHAS I and AHAS III, each with limited remnants of the other peptide. The catalytic properties of the large subunits have been characterized and compared with those of extracts containing the intact enzyme or of purified enzymes. Antisera to the isolated subunits have been used in Western blot (immunoblot) analyses for qualitative and semiquantitative determinations of the presence of the polypeptides in extracts. The large subunits of AHAS isozymes I and III have lower activities than the intact enzymes: Vmax/Km is 20 to 50 times lower in both cases. However, for AHAS I, most of this difference is due to the raised Km of the large subunit alone, while for AHAS III, it is due to a lowered Vmax. The substrate specificities, R, of large subunits are close to those of the intact enzymes. The catalytic activity of the large subunits of AHAS I is dependent on flavin adenine dinucleotide (FAD), as is that of the intact enzyme, although the apparent affinities of the large subunits alone for FAD are 10-fold lower. Isolated subunits are insensitive to valine inhibition. Nearly all of the properties of the intact AHAS isozyme I or III can be reconstituted by mixing extracts containing the respective large and small subunits. The mixing of subunits from different enzymes does not lead to activation of the large subunits. It is concluded that the catalytic machinery of these AHAS isozymes is entirely contained within the large subunits. The small subunits are required, however, for specific stabilization of an active conformation of the large subunits as well as for value sensitivity.
A Protein Farnesyl Transferase Involved in Abscisic Acid Signal Transduction in <b> <i>Arabidopsis</i> </b> (1996)

The hormone abscisic acid (ABA) modulates a variety of developmental processes and responses to environmental stress in higher plants. A collection of mutations, designated era, in Arabidopsis thaliana that confer an enhanced response to exogenous ABA includes mutations in the Era1 gene, which encodes the beta subunit of a protein farnesyl transferase. In yeast and mammalian systems, farnesyl transferases modify several signal transduction proteins for membrane localization. The era1 mutants suggest that a negative regulator of ABA sensitivity must be acted on by a farnesyl transferase to function.
Preferential Amplification of Pathogenic Sequences (2015)

The application of next generation sequencing (NGS) technology in the diagnosis of human pathogens is hindered by the fact that pathogenic sequences, especially viral, are often scarce in human clinical specimens. This known disproportion leads to the requirement of subsequent deep sequencing and extensive bioinformatics analysis. Here we report a method we called "Preferential Amplification of Pathogenic Sequences (PATHseq)" that can be used to greatly enrich pathogenic sequences. Using a computer program, we developed 8-, 9-, and 10-mer oligonucleotides called "non-human primers" that do not match the most abundant human transcripts, but instead selectively match transcripts of human pathogens. Instead of using random primers in the construction of cDNA libraries, the PATHseq method recruits these short non-human primers, which in turn, preferentially amplifies non-human, presumably pathogenic sequences. Using this method, we were able to enrich pathogenic sequences up to 200-fold in the final sequencing library. This method does not require prior knowledge of the pathogen or assumption of the infection; therefore, it provides a fast and sequence-independent approach for detection and identification of human viruses and other pathogens. The PATHseq method, coupled with NGS technology, can be broadly used in identification of known human pathogens and discovery of new pathogens.
Optimizing CRISPR/Cas9 for high-expression genome loci in industrial yeast strains (2017)

[Excerpt] The yeast Saccharomyces cerevisiae is one of the key cell factories for the production of bio-based chemicals, from fuels and bulk chemicals to active pharmaceuticals. Generally recognized as safe (GRAS) by the U. S. Food and Drug Administration and with a broad array of tools available at the molecular level, S. cerevisiae has been successfully manipulated for a wide range of applications. For large-scale fermentations, particularly in biorefineries, yeast cells must perform under harsh conditions, such as fluctuating pH and temperature, high osmotic pressure and presence of inhibitors derived from biomass hydrolysis. In this context, robust and stress-tolerant yeast chassis are required to attain high titers and product yields [1]. Industrial environments have been identified as a bioresource of yeast strains with higher robustness and fermentation performance and distinct strains have been isolated. [...]
Synthesis of 8‐cyano‐1,4‐dihydro‐4‐oxopyrrolo[1,2‐a]pyrimidine‐3‐carboxylic acids as potential antimicrobial agents (1987)

Abstract The preparation of a variety of 8‐cyano‐1,4‐dihydro‐7‐phenyl‐4‐oxopyrrolo[1,2‐ a ]pyrimidine‐3‐carboxylicacids and 8‐cyano‐1,4‐dihydro‐7‐ p ‐fluorophenyl‐4‐oxopyrrolo[1,2‐ a ]pyrimidine‐3‐carboxylic acids is described.