gebhart/patrepeval huggingface dataset:
Properties of sickle-cell haemoglobin (1957)

Research Article| February 01 1957 Properties of sickle-cell haemoglobin A. C. Allison A. C. Allison 1Medical Research Council Unit for Research in Cell Metabolism, Department of Biochemistry, University of Oxford Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1957) 65 (2): 212–219. https://doi.org/10.1042/bj0650212 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation A. C. Allison; Properties of sickle-cell haemoglobin. Biochem J 1 February 1957; 65 (2): 212–219. doi: https://doi.org/10.1042/bj0650212 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1957 CAMBRIDGE UNIVERSITY PRESS1957 Article PDF first page preview Close Modal You do not currently have access to this content.
ChemInform Abstract: Pentacosa‐10,12‐diynoic Acid/Henicosa‐2,4‐diynylamine Alternate‐Layer Langmuir‐Blodgett Films: Synthesis, Polymerization, and Electrical Properties. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Chronopharmacology of Trichlormethiazide in Rats: (III) Influence on Serum Triglyceride and Glucose (1991)

Trichlormethiazide was given orally to rats at 10 a.m. or 10 p.m. for 14 days. The diuretic effects of the agent at 10 a.m. were greater than those at 10 p.m. on day 14. Scrum concentrations of triglyceride and glucose increased in both trials. The increments in these parameters were enhanced following trichlormethiazide at 10 a.m. These data indicate that the diuretic effects of trichlormethiazide and its untoward influences on serum metabolic parameters might vary with the administration time during a repeated therapy.
The Personality Conception of the Legal Entity. By A. Nékám. Harvard Studies in the Conflict of Laws, 3. Cambridge, Massachusetts: Harvard University Press. 1938. 131 pp. ($2.00.) (1939)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Biomarkers of HIV related central nervous system disease (2008)

In this review we critically assess biomarkers of the direct effects of HIV related brain disease. This area is becoming increasingly complex because of the presence of confounds and varying degrees of activity of HIV brain disease. Sensitive and specific biomarkers are urgently needed although existing biomarkers do have some utility. The review will focus on the practical implications of the more established biomarkers. We discuss blood, cerebrospinal fluid and neurophysiological biomarkers but not neuroimaging techniques as they are beyond the scope of this review.
Thickness dependence of acousto−optic diffraction efficiency in ZnO−film optical waveguides (1975)

The thickness dependence of the efficiency of the Bragg diffraction between the same optical modes (TE0→TE0, TM0→TM0) by acoustic surface waves in ZnO−film optical waveguides is investigated at an acoustic frequency of 130 MHz and a film thickness from 0.6 to 8.0 μm. It is observed that the efficiencies for both the TE0 and the TM0 modes vary more than 2 orders of magnitude with the film thickness.
Los juramentos e imprecaciones de los Usatges de Barcelona (1995)

espanolAnalisis del usatge 171 senalando sus precedentes biblicos, visigoticos, carolingios, judeomusulmanes y epigraficos. Destaca la desaparicion de las clausulas imprecatorias en la documentacion, sobre todo por las reformas procesales del Concilio IV de Letran. Edicion del usatge 171 y en columna paralela de los textos biblicos de donde estan tomadas sus disposiciones EnglishAnalysis of the usatge 171 pointing out their biblical, Frankish, Jewish, Moslem and epigraphish precedents. It emphasizes the disappearance of the clauses with curses in the documentation in the face of the procedural reformations of the IV Council of Letran. Edition of the usatge 171 and in a parallel column of the biblical texts of where they are taken their dispositions
Factors Affecting Distributed System Security (1987)

Recent work examining distributed system security requirements. is critiqued. A notion of trust based on distributed system topology and distributed system node evaluation levels proposed in that work is shown to be deficient. The notion fails to make allowances for the distributed system physical security environment, security factors related to the management of distributed systems by more than one jurisdictive authority, and the interactions that can occur between nodes supporting different mandatory and discretionary security mechanisms.
Autonomic Network Engineering: Bridging the Gap Between Research, Standards and Industry (2013)

Autonomic networking aims at mastering the growing complexity of daily network operation. Large research efforts have been spent to design clean-slate and evolutionary architectures for autonomic networks, yet with limited adoption by the telecommunication industry. In order to fill the gaps between research, standards and industry, a global effort involving all stakeholders and a systematic roadmap are required. In this paper, we highlight three essential requirements to fulfil: the need for a unified management framework in an end-to-end and multi-technology environment, the need for test and validation of large-scale implementations to build trust from network operators and the need for standardized interfaces harmonizing the communication between autonomic components.
A mucosally targeted subunit vaccine candidate eliciting HIV-1 transcytosis-blocking Abs (2004)

A vaccine that would engage the mucosal immune system against a broad range of HIV-1 subtypes and prevent epithelial transmission is highly desirable. Here we report fusing the mucosal targeting B subunit of cholera toxin to the conserved galactosylceramide-binding domain (including the ELDKWA-neutralizing epitope) of the HIV-1 gp41 envelope protein, which mediates the transcytosis of HIV-1 across the mucosal epithelia. Chimeric protein expressed in bacteria or plants assembled into oligomers that were capable of binding galactosyl-ceramide and G(M1) gangliosides. Mucosal (intranasal) administration in mice of the purified chimeric protein followed by an i.p. boost resulted in transcytosis-neutralizing serum IgG and mucosal IgA responses and induced immunological memory. Plant production of mucosally targeted immunogens could be particularly useful for immunization programs in developing countries, where desirable product traits include low cost of manufacture, heat stability, and needle-free delivery.
Injectable Sealants Based on Silk Fibroin for Fast Hemostasis and Wound Repairing (2023)

Uncontrollable blood loss poses fatality risks and most recently developed sealants still share common limitations on controversial components, degradability, mechanical strength or gelation time. Herein, series of injectable sealants based on silk fibroin (SF) is developed. Random coil/β-sheet conformation transition in SF is achieved by forming dendritic intermediates under induction of the structurally compatible and chemically complementary assembly peptide (Ac-KAEA-KAEA-KAEA-KAEA-NH<sub>2</sub> , KA<sub>16</sub> ). A ratio of 1:5 (KA-SF-15) shown an accelerating gelation process (≈12 s) and enhanced mechanical strength at physiological conditions. The interweaved nanofibers effectively impeded the bleeding within 30 s and no obvious adverse effects are observed. The supramolecular interactions and in vivo degradation benefit the inflammatory host cells infiltration and cytokines diffusion. Without any exogenous factors, the increased expression of VEGF and PDGF led to a positive feedback regulation on fibroblasts and vascular endothelial cell growth/proliferation and promoted the wound healing. These findings indicated the few assembly-peptide can accelerate fibroin gelation transition at a limited physiological condition, and the injectable amino acid-based sealants show obvious advantages on biocompatibility, degradability, rapid gelation and matched strength, with strong potential to act as next generation of biomedical materials.
Automated coronary calcification detection and scoring (2005)

An automated method for coronary calcification detection from ECG-triggered multi-slice CT data is presented. The method first segments the heart region. In the obtained volume candidate objects are extracted by thresholding. They include coronary calcification, calcium located elsewhere in the heart, for example, in the valves or the myocardium, and other high density structures mostly representing noise and bone. A set of 57 features is calculated for each candidate object. In the feature space objects are classified with a k-NN classifier and feature selection in three consecutive stages. The method is tested on 51 scans of the heart. They contain 320 calcification in the coronary arteries, 291 in the aorta and 62 calcifications in the heart. The system correctly detected 177 calcifications in the coronaries at the expense of 56 false positive objects. On average the method makes 3.8 errors per scan.
특집기획 : 한국한문교육학회 2008년 하계학술대회 및 제30차 전국학술대회 ; 한문 교과서 단원 구성의 원리와 방안 (2008)

이 연구는 이전 한문과 교육과정에 따른 중학교 한문 교과서의 단원 구성 방식과 단원 구성 체제를 비평적으로 검토한 뒤, 한문 교과서의 일반적 단원 구성 원리를 몇 가지 제시하고, 이를 바탕으로 대단원 구성 방식과 소단원 구성 체제(體制)를 중심으로 중학교 한문 교과서 구성 방안을 시론(試論)한 것이다. 이전 교육과정에 따른 중학교 한문 교과서를 단원 구성 방식과 체제 관점에서 비평적으로 검토한 결과, 교육과정의 한자, 한자어, 한문의 영역 구분으로 인하여 대단원 구성 방식 또한 한자, 한자어, 한문의 순차적(順次的) 구조 형태를 취했으며, 대단원 구성의 기제 또한 주제 및 소재, 문종(文種), 영역 그리고 목표 등이 혼종된 양상을 보였다. 그리고 대단원 내의 개별 소단원 전개의 원리와 단계 측면에서 대체로 분절적, 개별적인 조직 방식을 따랐다. 또한 한자의 뜻과 쓰임, 한자어의 짜임과 풀이, 한자 및 한자어의 활용, 문장의 구조와 형식, 평가라는 고정된 틀을 반복하여 구성 요소의 획일화를 소단원 구성 체제의 문제점으로 제기할 수 있었다. 본격적 단원 구성 방안 논의에 앞서, 필자는 교육과정 내용 상세화, 교수 학습 과정 안내, 자기 주도적 학습 활동 지향, 그리고 영역 통합을 한문 교과서 단원 구성 방식과 단원 구성 체제의 일반적 원리로 제시하되, 한문과의 교과적 특수성을 반영하여 설명하고 예시하였다. 이를 바탕으로 필자는, 주제 중심 통합 단원 구성과 교수 학습 과정 중심 소단원 구성 체제를 중심으로 구성 방안을 구체화하였다. 주제 중심 통합 단원 구성은 동양 고전 문화에 내재한 가치, 이념, 주제를 중심으로 이를 구현하기 위해 다양한 소재, 제재, 문종을 활용하고, 주제와 제재의 특성과 연계된 목표를 수용하여, 결과적으로 주제, 문종, 목표가 상호 유기적으로 결합된다는 점에서 장점이 있음을 강조하였다. 그리고 기존의 중학교 한문 교과서의 구성 체제의 문제점으로 지적된 구성 요소의 획일화를 극복하기 위한 방안의 하나로, 교사와 학습자의 교수 학습의 과정, 절차, 단계를 고려한 교수 학습 과정 중심 소단원 구성 체제를 제안하였다.
Self-assembled titania–silica–sepiolite based nanocomposites for water decontamination (2009)

This work describes the preparation of microchannel structured monolithic pieces by the “ice-segregation induced self-assembly” (ISISA) process. The monoliths exhibit a hierarchical structure composed of homogeneously mixed colloidal silica resulting from hydrolysis and condensation of an alkoxysilane precursor (e.g., TEOS) and TiO2 polycrystalline nanoparticles adsorbed onto sepiolite fibres. The combination of such a different species into a single macroporous structure provides a multifunctional material capable of water decontamination by pollutant removal from aqueous media (via adsorption on sepiolite) and subsequent elimination by UV irradiation (via photocatalytic oxidation on TiO2nanoparticles). The performance of the resulting materials has been studied using two organic compounds often present in wastewater such as p-nitrophenol (PNP) and methylene blue (MB).
A critical review of the physiological importance and analysis of sperm movement in mammals (1997)

The identification of human sperm hyperactivated motility has potential importance in sperm function tests, as well as in quality control assays and in reproductive toxicology investigations. However, relatively little is known about this phenomenon and the variety of definitions used for hyperactivation has led to a great deal of confusion as to its occurrence and physiological relevance. This presentation is a critical review of a number of aspects of hyperactivated motility, including its identification and potential role(s) in mammalian fertilization. The initial sections of the review consider the mechanisms involved in the development and maintenance of mammalian sperm motility, and the structural and functional changes in spermatozoa which occur during transport through the female reproductive tract. The methods available for the quantification of aspects of sperm movement are also discussed, with an historical overview of sperm movement analysis.
Two‐flux radiation‐field model for an annular packed‐bed photocatalytic oxidation reactor (1997)

Abstract One of the remaining challenges in application of heterogeneous photocatalysis for treatment of air streams containing dilute VOCs is to design a cost‐effective photocatalytic reactor that simultaneously allows efficient contact of the contaminated air and solid catalyst while uniformly irradiating the solid catalyst with light. A pseudohomogeneous model was developed to study effects of system parameters on process performance for a gas–solid lamp‐in‐tube annular‐photocatalytic‐oxidation (PCO) reactor in which the annular space is filled with photocatalyst‐coated packing. In this model the flow field is assumed to be uniform and radial diffusion negligible. Homogeneous reactions are neglected. Heterogeneous reaction rates follow Langmuir–Hinshelwood–Houghen–Watson kinetics with rate parameters extracted from independent experiments. A 1:D “two‐flux” incidence submodel is used to account for the radial UV light distribution throughout the reactor annular space. This submodel requires knowledge of the UV lamp radiant emittance, the optical characterstics of the catalytic thin‐film coating, and the UV irradiance at the outer wall of the reactor and contains only a single adjustable parameter—the mean free path between photon–catalyst interactions. The model was validated with experimental performance measurements for destruction of acetone and isopropyl alcohol in a bench‐scale photoreactor. The validated model can be used to predict the optimum catalyst film thickness for given reactor dimensions, packing shape and size, and VOC abatement problem.
Critical Path Selection for Delay Test Considering Coupling Noise (2008)

Identifying the set of real critical paths of a circuit is an important step in delay testing. Since path delays are vector dependent, the set of critical paths selected depends on the vectors assumed when estimating the path delays. To find the real critical paths, it is important to consider the effect of dynamic (vector dependent) delay effects such as coupling noise, supply noise etc. during path selection. In this work a methodology to incorporate the effect of coupling noise during path selection is described. For any given path, both logic and timing constraints are extracted and a constrained optimization problem is formulated to estimate the maximum path delay in the presence of coupling noise.
Detection and Analysis of Emotion from Speech Signals (2017)

Abstract Recognizing emotion from speech has become one the active research themes in speech processing and in applications based on human-computer interaction. This paper conducts an experimental study on recognizing emotions from human speech. The emotions considered for the experiments include neutral, anger, joy and sadness. The distinuishability of emotional features in speech were studied first followed by emotion classification performed on a custom dataset. The classification was performed for different classifiers. One of the main feature attribute considered in the prepared dataset was the peak-to-peak distance obtained from the graphical representation of the speech signals. After performing the classification tests on a dataset formed from 30 different subjects, it was found that for getting better accuracy, one should consider the data collected from one person rather than considering the data from a group of people.
Array processor supercomputers (1989)

The authors describe the range of hardware variations of array processors, a form of SIMD (simple instruction stream, multiple dates stream architecture), comparing and contrasting the significant differences among them and briefly illustrating the wide range of algorithms that can effectively utilize them. Three applications are reviewed. The first application, image convolution, represents the traditional numerically computationally intensive areas of application. SIMD array processors are sufficiently powerful to process digital imagery in real time easily. The second application, an example of real-time database management, is the air traffic control problem. The problem cannot be solved today by networks of computers that are successfully used in similar, less time-critical applications. With an array processor there is sufficient real time remaining after the present system tasks are accomplished to realize additional system enhancements. The third application area, graph algorithms, which is more theoretical, is representative of problems for which the simplicity of the array processor solution results in an execution time better than the best theoretical case for a conventional sequential implementation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Comparison of DC, RF, and dispersion properties of SOI and strained-SOI N-MOSFETs (2005)

The operating performance of SOI and strained-SOI N-MOSFETs are compared. In particular, these properties are examined in detail: 1) electron mobility and DC characteristics, 2) high frequency behavior, 3) dispersion and self-heating effects, and 4) buried oxide interface trap density. Our results demonstrate that SSOI technology can improve f/sub t/ and f/sub max/ conservatively by up to 50% without excessive dispersion/self-heating. Furthermore, measurements indicate that the SSOI wafer bonding process can produce an acceptable buried oxide interface trap density.
In vitro susceptibility testing of ciclopirox, terbinafine, ketoconazole and itraconazole against dermatophytes and nondermatophytes, and in vitro evaluation of combination antifungal activity (2003)

In vitro susceptibility testing indicates that ciclopirox may have a broad antimicrobial profile including dermatophytes, yeasts and other nondermatophytes. Terbinafine is extremely potent against dermatophytes. In vitro evaluation of activity of ciclopirox and terbinafine suggests many instances of synergy or additivism; for ciclopirox and itraconazole there may be indifference, synergy or additivism.
Evidence for Triacylglycerol Synthesis in the Lumen of Microsomes via a Lipolysis-Esterification Pathway Involving Carnitine Acyltransferases (1999)

In this study a pathway for the synthesis of triacylglycerol (TAG) within the lumen of the endoplasmic reticulum has been identified, using microsomes that had been preconditioned by depleting their endogenous substrates and then fusing them with biotinylated phosphatidylserine liposomes containing CoASH and Mg(2+). Incubating these fused microsomes with tri[(3)H] oleoylglycerol and [(14)C]oleoyl-CoA yielded microsome-associated triacylglycerol, which resisted extensive washing and had a [(3)H]:[(14)C] ratio close to 2:1. The data suggest that the precursor tri[(3)H]oleoylglycerol was hydrolyzed by microsomal lipase to membrane-bound di[(3)H]oleoylglycerol and subsequently re-esterified with luminal [(14)C]oleoyl-CoA. The accumulation of TAG within the microsomes, even when overt diacylglycerol acyltransferase (DGAT I) was inactive, is consistent with the existence of a latent diacylglycerol acyltransferase (DGAT II) within the microsomal lumen. Moreover, because luminal synthesis of TAG was carnitine-dependent and markedly reduced by glybenclamide, a potent carnitine acyltransferase inhibitor, microsomal carnitine acyltransferase appears to be essential for trafficking the [(14)C]oleoyl-CoA into the microsomal lumen for subsequent incorporation into newly synthesized TAG. This study thus provides the first direct demonstration of an enzymatic process leading to the synthesis of luminal triacylglycerol, which is a major component of very low density lipoproteins.
Cumulative Gains Model Quality Metric (2009)

This paper proposes a more comprehensive look at the ideas of KS and Area Under the Curve (AUC) of a cumulative gains chart to develop a model quality statistic which can be used agnostically to evaluate the quality of a wide range of models in a standardized fashion. It can be either used holistically on the entire range of the model or at a given decision threshold of the model. Further it can be extended into the model learning process.
Antigenic Regions on the β Chain of Human Chorionic Gonadotropin and Development of Hormone Specific Antibodies (1987)

Five peptides corresponding to four regions of the beta chain of human chorionic gonadotropin (hCG), were synthesized, purified and characterized. The four regions studied were selected on the basis of sequence differences between the beta chain of hCG (beta hCG) and the beta chains of related hormones. The peptides were found to bind rabbit and mouse anti-hCG antibodies as well as rabbit anti-beta chain antibodies, but did not bind antibodies against the alpha chain or against other hormones. All the peptides, even in their free form, were able to elicit high titer antisera in both rabbits and mice. In all cases, anti-peptide antisera bound to the immunizing peptide as well as to the native hCG and the isolated beta chain. These anti-peptide antisera did not bind to unrelated peptides, the alpha chain of hCG or to other hormones with very similar beta chains such as human luteotropic hormone (hLH), ovine luteotropic hormone (oLH) and equine chorionic gonadotropin (eCG). Since the areas represented by these peptides elicit antibodies that are specific for human beta hCG, they can formulate the basis for the development of discriminatory reagents for the beta chain of hCG.
On the charge storage and decay mechanism in silicon dioxide (2002)

A mechanism for both the storage and the decay of charge in a charged silicon dioxide layer is proposed. The oxide layer needs neutral traps (NETs) to obtain stable trapped negative charge, after having been charged, resulting in an electret that can be applied in microphones. The hydrolysis of the silanol groups, followed by charge injection, results in an electrochemical reaction with immobile SiO as one of the reaction products. Decay of the stable charge thus obtained can occur by the clustering of water molecules at inner silanol groups, resulting in a conductive hydrogen bonded network, which eventually leads to the discharge of the electret.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Dissociative recombination coefficient for low temperature equilibrium cesium plasma (2002)

The dissociative recombination (DR) coefficient in decaying low temperature Cs plasma is calculated based on the experimentally measured relaxation time of decaying Cs plasma by L. P. Harris [J. Appl. Phys. 36, 1543 (1965)]. Results showed that DR is the dominant recombination process over three-body recombination at T&lt;1650 K and PCs of 0.5–20 Torr (67–2666 Pa). The estimated DR coefficient for Cs is between 10−12 and 10−13 m3/s at T&lt;1750 K and PCs of 0.5–20 Torr. Although theory predicts that DR coefficient solely depends on temperature, the present results show pressure dependency. For typical operating conditions in thermionic converters (T&lt;1650 K and PCs⩽400 Pa), DR is constant and ∼5.26×10−13 m3/s.