gebhart/patrepeval huggingface dataset:
Low-Dose Mianserin in Treatment of Acute Neuroleptic-Induced Akathisia (1998)

Director of Research, Tirat Carmel Mental Health Center, POB 9, Tirat Carmel 30200, Israel (Puyorovsky). Department of Statistics and Operations Research, Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, Israel (Fuchs). Director of Research, Gehah Psychiatric Hospital, POB 102, Petah Tiqva 49100, Israel (Weizman).
An automatic tool for the analysis of natural language requirements. (2005)

Using automatic tools for the quality analysis of Natural Language (NL) requirements is recognized as a key factor for achieving software quality. Unfortunately few tools and techniques for the NL requirements analysis are currently available. This paper presents a methodology and a tool (called QuARS- Quality Analyzer for Requirement Specifications) for analyzing NL requirements in a systematic and automatic way. QuARS allows requirements engineers to perform an initial parsing of the requirements in order to automatically detect potential linguistic defects that could cause interpretation problems at subsequent stages in developing the software. This tool is also able to partially support the consistency and completeness analysis by clustering the requirements according to specific topics.
Changes in action potential duration alter reliance of excitatory synaptic transmission on multiple types of Ca2+ channels in rat hippocampus (1996)

It has been established that multiple types of Ca2+ channels participate in triggering neurotransmitter release at central synapses, but there is uncertainty about the nature of their combined actions. We investigated synaptic transmission at CA3-CA1 synapses of rat hippocampal slices and asked whether the dependence on omega-CTx-GVIA-sensitive N-type channels and omega-Aga-IVA-sensitive P/Q-type Ca2+ channels can be altered by physiological mechanisms. The reliance on multiple types of Ca2+ channels was not absolute but depended strongly on the amount of Ca2+ influx through individual channels, which was manipulated by prolonging the presynaptic action potential with the K+ channel blocker 4-aminopyridine (4-AP) and by varying the extracellular Ca2+ concentration ([Ca2+]o). We quantified the influence of spike broadening on Ca2+ influx through various Ca2+ channels by imposing mock action potentials on voltage-clamped cerebellar granule neurons. In field recordings of the EPSP in hippocampal slices, action potential prolongation increased the EPSP slope by 2-fold and decreased its reliance on either N-type or P/Q-type Ca2+ channels. The inhibition of synaptic transmission by N-type channel blockade was virtually eliminated in the presence of 4-AP, but it could be restored by lowering [Ca2+]o. These results rule out a scenario in which a significant fraction of presynaptic terminals rely solely on N-type channels to trigger transmission. The change in sensitivity to the neurotoxins with 4-AP could be explained in terms of a nonlinear relationship between Ca2+ entry and synaptic strength, which rises steeply at low [Ca2+]o, but approaches saturation at high [Ca2+]o. This relationship was evaluated experimentally by varying [CA2+]o in the absence and presence of 4-AP. One consequence of this relationship is that down-modulation of presynaptic Ca2+ channels by various modulators would increase the relative impact of spike broadening greatly.
1,4-Dipole-metalated quinone strategy to (.+-.)-4-demethoxydaunomycinone and (.+-.)-daunomycinone. Annelation of benzocyclobutenedione monoketals with lithioquinone bisketals (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT1,4-Dipole-metalated quinone strategy to (.+-.)-4-demethoxydaunomycinone and (.+-.)-daunomycinone. Annelation of benzocyclobutenedione monoketals with lithioquinone bisketalsJohn S. Swenton, D. Keith Anderson, Daniel K. Jackson, and Lakshmi NarasimhanCite this: J. Org. Chem. 1981, 46, 24, 4825–4836Publication Date (Print):November 1, 1981Publication History Published online1 May 2002Published inissue 1 November 1981https://pubs.acs.org/doi/10.1021/jo00337a002https://doi.org/10.1021/jo00337a002research-articleACS PublicationsRequest reuse permissionsArticle Views422Altmetric-Citations52LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A table driven database and applications generator for accelerator control systems (2002)

The proposed system of describing ring data should make it easy for the user to do high-level application development by hiding details behind logical naming schemes. It will guarantee system-wide configuration data integrity by keeping it defined in one place, in the central database. The decrease in dependence on skilled computer personnel to maintain this information is well worth the added cost in computer hardware required to support it.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A study of far-field patterns from high performance 1.3-&#181;m InGaAsP-InP edge-emitting LED's (1983)

Liquid-phase epitaxy InGaAsP-InP 1.3-µm edge-emitting LED's are fabricated with a very simple Schottky-delineated stripe structure. With a stripe 50 µm wide and 200-250 µm long, typical characteristics of these devices include 170 µW of optical power coupled into a 60-µm core 0.2-NA graded index fiber, 600-Å spectral halfwidths, 2-5-ns risetimes. Unlike GaAs-GaAlAs edge-emitting LED's, best results of coupling efficiency are obtained with InGaAsP-InP LED's whose active layer thickness is in the range 0.12-0.15 µm, due to asymmetry in the far-field patterns. Our study of these far-field patterns shows that this asymmetry is governed by the quality of the active layer material located near the InGaAsP-nInP hetero-interface.
Assessment of the Atrial Contribution to Cardiac Performance by a Noninvasive Photoplethysmographic Technique (1973)

Atrial contribution to ventricular performance was assessed by a non-invasive photoplethysmographic technique in two patients with complete atrioventricular block. The amplitude of the dorsalis pedis pulse volume showed a parabolic relationship to the P-Q interval at ventricular pacing rates ranging between 51 and 103/min. The optimal P-Q intervals were inversely related to the ventricular rate. The interval between the onset of the QRS complex and the foot of the dorsalis pedis pulse wave, Δt (Q-f), also showed a parabolic relationship to the P-Q interval, but the changes in Δ t (Q-f) were opposite to those in pulse amplitude. Optimal P-Q intervals were associated with shortest Δt (Q-f) and highest pulse volume amplitudes at all ventricular rates. Pulse wave velocity along the femoralis-dorsalis pedis segment was constant and independent of the P-Q interval and of variations in pulse volume amplitude.
A modified P&amp;O MPPT control of photovoltaic systems (2011)

In this paper, a modified P&O algorithm is proposed to improve MPPT performance of photovoltaic (PV) systems. Experimental results show the proposed P&O MPPT algorithm offers faster and more accurate MPPT performances.
The Autonomic Nervous System and Heart Failure (2014)

The pathophysiology of heart failure (HF) is characterized by hemodynamic abnormalities that result in neurohormonal activation and autonomic imbalance with increase in sympathetic activity and withdrawal of vagal activity. Alterations in receptor activation from this autonomic imbalance may have profound effects on cardiac function and structure. Inhibition of the sympathetic drive to the heart through β-receptor blockade has become a standard component of therapy for HF with a dilated left ventricle because of its effectiveness in inhibiting the ventricular structural remodeling process and in prolonging life. Several devices for selective modulation of sympathetic and vagal activity have recently been developed in an attempt to alter the natural history of HF. The optimal counteraction of the excessive sympathetic activity is still unclear. A profound decrease in adrenergic support with excessive blockade of the sympathetic nervous system may result in adverse outcomes in clinical HF. In this review, we analyze the data supporting a contributory role of the autonomic functional alterations on the course of HF, the techniques used to assess autonomic nervous system activity, the evidence for clinical effectiveness of pharmacological and device interventions, and the potential future role of autonomic nervous system modifiers in the management of this syndrome.
Bicyclo[2.1.1]hex-2-ene. Electrophilic addition reactions (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBicyclo[2.1.1]hex-2-ene. Electrophilic addition reactionsF. Thomas BondCite this: J. Am. Chem. Soc. 1968, 90, 19, 5326–5328Publication Date (Print):September 1, 1968Publication History Published online1 May 2002Published inissue 1 September 1968https://pubs.acs.org/doi/10.1021/ja01021a079https://doi.org/10.1021/ja01021a079research-articleACS PublicationsRequest reuse permissionsArticle Views166Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Architecture for Highly Reliable Embedded Flash Memories (2007)

Non-volatile embedded Flash (eFlash) memories are very popular in Systems-on-a-Chip (SoC). These memories are based on the well-known floating gate concept. While densities and quality constraints are increasing, the reliability becomes a growing up issue. For eFlash memories, endurance and retention issues are at the root of reliability losses. To improve reliability, eFlash memories designs usually use techniques such as Error Correcting Codes (ECC), Redundancy and Threshold Voltage (V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> ) Analysis. In this paper, an implementation of these techniques is proposed through an architecture. Thanks to eFlash specificity, the correction capacity is improved via a double correction scheme. Additionally, each time an operation is performed on a memory element, a smart reliability management tracks online errors and weak bits. When few issues in a word catch out the double error correction scheme, a refresh and repair with low redundancy process is engaged.
Phase IIb randomized trial of adjunct immunotherapy in patients with first-diagnosed tuberculosis, relapsed and multi-drug-resistant (MDR) TB (2011)

Placebo-controlled, randomized, phase 2b trial was conducted in 34 adults comprising 18 first-diagnosed (52.9%), 6 relapsed (17.6%), and 10 MDR-TB (29.4%) cases to investigate the safety and efficacy of an oral immune adjunct (V5). The immunotherapy (N = 24) and placebo (N = 10) arms received once-daily tablet of V5 or placebo for one month in addition to conventional anti-TB therapy (ATT) administered under directly observed therapy (DOT).The enlarged liver, total bilirubin, erythrocyte sedimentation rate, lymphocyte and leukocyte counts improved significantly in V5 recipients (P = 0.002; 0.03; 8.3E-007; 2.8E-005; and 0.002) but remained statistically unchanged in the placebo group (P = 0.68; 0.96; 0.61; 0.91; and 0.43 respectively). The changes in hemoglobin and ALT levels in both treatment arms were not significant. The body weight increased in all V5-treated patients by an average 3.5 ± 1.8 kg (P = 2.3E-009), while 6 out of 10 patients on placebo gained mean 0.9 ± 0.9 kg (P = 0.01). Mycobacterial clearance in sputum smears was observed in 78.3% and 0% of patients on V5 and placebo (P = 0.009). The conversion rate in V5-receiving subjects with MDR-TB (87.5%) seemed to be higher than in first-diagnosed TB (61.5%) but the difference was not significant (P = 0.62). Scoring of sputum bacillary load (range 3-0) at baseline and post-treatment revealed score reduction in 23 out of 24 (95.8%) V5 recipients (from mean/median 2.2/3 to 0.3/0; P = 6E-010) but only in 1 out of 10 (10%) patients on placebo (1.9/1.5 vs. 1.8/1; P = 0.34). No adverse effects or TB reactivation were seen at any time during follow-up. V5 is safe as an immune adjunct to chemotherapeutic management of TB and can shorten substantially the duration of treatment.
Thieno[3,2-<i>b</i>]thiophene−Diketopyrrolopyrrole-Containing Polymers for High-Performance Organic Field-Effect Transistors and Organic Photovoltaic Devices (2011)

We report the synthesis and polymerization of a novel thieno[3,2-b]thiophene-diketopyrrolopyrrole-based monomer. Copolymerization with thiophene afforded a polymer with a maximum hole mobility of 1.95 cm(2) V(-1) s(-1), which is the highest mobility from a polymer-based OFET reported to date. Bulk-heterojunction solar cells comprising this polymer and PC(71)BM gave a power conversion efficiency of 5.4%.
What`s new in artificial lift. Part 1 (1994)

In the first article of this two-part series, new developments were presented for electrical submersible pumps and accessories, gas lift, and controls and measurement. This concluding article extends the review of artificial lift innovations to include beam pumping and progressive cavity (PC) pumps. Described here are improvements in beam pumping which include advanced sucker rods and pumping units, fluid level instruments, pump-off control (POC) and efficiency monitoring/management systems, pump sand control, surface pollution containment and a shared-motor for multiple wells. For progressive cavity pump improvements, three companies have introduced new rod guides, a modified tubing anchor catcher, round continuous rods, a PC variable frequency drive and a multilobe pump system. And status of a 20-company sponsored project for PC pump improvement is outlined.
Ultra-wideband Performance in a Dense Multipath Environment with Time and Spatial Diversity (2007)

This paper analyzes the performance of direct sequence ultra-wideband (DS-UWB) systems in a very dense and realistic multipath channel scenario with temporal and spatial diversity, considering Monte-Carlo simulation method and semi-analytical development. This work analyzes the impact of antenna elements and the number of rake fingers on the system performance, emphasizing the effects of the pulse shape correlation.
Recent Applications of Chiral Ferrocene Ligands in Asymmetric Catalysis (2007)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enhancement of LFA-1-Mediated T Cell Adhesion by Human T Lymphotropic Virus Type 1 p12I1 (2006)

Cell-to-cell transmission of retroviruses, such as human T lymphotropic virus type 1 (HTLV-1), is well documented, but the roles of viral regulatory or other nonstructural proteins in the modulation of T cell adhesion are incompletely understood. In this study we tested the role of the HTLV-1 accessory protein, p12(I), on LFA-1-mediated cell adhesion. p12(I) is critical for early HTLV-1 infection by causing the release of calcium from the endoplasmic reticulum to activate NFAT-mediated transcription. We tested the role of this novel viral protein in mediating LFA-1-dependent cell adhesion. Our data indicated that T cells expressing a mutant HTLV-1 provirus that does not produce p12(I) mRNA (ACH.p12(I)) exhibited reduced LFA-1-mediated adhesion compared with wild-type HTLV-1-expressing cells (ACH). Furthermore, the expression of p12(I) in Jurkat T cells using lentiviral vectors enhanced LFA-1-mediated cell adhesion, which was inhibited by the calcium chelator BAPTA-AM, the calcium channel blocker SK&F 96365, and calpeptin, an inhibitor of the calcium-dependent protease calpain. Similar to the intracellular calcium mobilizer, thapsigargin, the expression of p12(I) in Jurkat T cells induced cell surface clustering of LFA-1 without changing the level of integrin expression. Our data are the first to indicate that HTLV-1 p12(I), in addition to enhancing T cell activation, promotes cell-to-cell spread by inducing LFA-1 clustering on T cells via calcium-dependent signaling.
Visualization of Customer Flow in an Office Complex over a Long Period (2010)

In facility management, analysis of customer trajectories in office complexes is considered critical. In this paper, we propose a novel approach for the visualization of customer flow in an office complex over a long period of time. We expressed the variation in the trajectories with respect to time by using a mixture model; this was used for the visualization of the trajectory flows. The effectiveness of our approach was evaluated from the results of the customer flow analysis experiments that were conducted in an office complex.
Performance Characteristics of a High-Sensitivity, Three-Wavelength, Total Scatter/Backscatter Nephelometer (1996)

As designed in the 1940s by Beuttell and Brewer, the integrating nephelometer offers a direct method of measuring light scattering by airborne particles without assumptions about particle composition, shape, or physical state. A large number of such instruments have been deployed; however, only a limited number of validation experiments have been attempted. This paper reports a set of closure experiments in which a gas-calibrated nephelometer is used to measure the scattering coefficient of laboratory-generated particles of known size and refractive index. Specifically, it evaluates the performance of a high-sensitivity, three-wavelength, total scatter/backscatter integrating nephelometer (TSI, Inc., model 3563). Sources of uncertainty associated with the gas-calibration procedure, with photon-counting statistics, and with nonidealities in wavelength and angular sensitivity are investigated. Tests with particle-free gases indicate that noise levels are well predicted by photon-counting statistics and that the nephelometer response is linear over a wide range of scattering coefficients. Tests with particles show average discrepancies between measured and predicted scattering of 4%–7%. Error analysis indicates that these discrepancies are within experimental uncertainty, which was dominated by particle generation uncertainty. The simulation of nephelometer response, which is validated by these tests, is used to show that errors arising from nephelometer nonidealities are less than 10% for accumulation-mode or smaller particles (i.e., size distributions for which the volume mean diameter is 0.4µm or less) and that significant differences exist between the total scatter and backscatter uncertainties. Based on these findings, appropriate applications of the model 3563 nephelometer am discussed.
Photoelectric Light-Scattering Photometer for Determining High Molecular Weights* (1950)

A photoelectric photometer designed for the measurement of absolute turbidity, dissymmetry, and depolarization of dilute solutions of high molecular weight materials, and hence determination of their molecular weights, is described. The photometer comprises essentially a monochromatic parallel primary beam of radiation, a six-sided scattering cell for measurements at 0°, 45°, 90°, and 135°, a multiplier phototube and galvanometer, a standard opal glass diffusor, and removable polarizer and analyzer. Turbidity is determined in terms of a ratio of deflections for the 90° scattering and for the primary beam reduced in intensity by neutral filters and diffused by an opal glass plate. Working relationships leading to determination of absolute turbidity are developed. These relationships include corrections for refraction and reflection effects, and for imperfect diffusion by the opal glass. The latter is evaluated by comparison of the opal glass with reflecting diffusors corrected for specular component of reflectance. The response of some multiplier photo-tubes is shown to be dependent on the plane of polarization of the incident radiation. Data illustrating the performance of the photometer include comparison of molecular weights of polystyrene fractions, beta-lactoglobulin, bovine serum albumin, lysozyme, sucrose octaacetate, Raleigh’s ratio and depolarization for benzene, turbidity of a “standard” polystyrene, and particle size of a GR-S latex, with data obtained by other methods or other investigators.
Characterization of Passive Optical Components by DSP-Based Optical Channel Estimation (2011)

Passive optical components with fine structures require a characterization method with high-resolution and fast measurement speed. In this letter, we extend the digital signal processing-based optical channel estimation to measure their transfer functions, including the intensity and phase responses. In the experiment, by using 16384-point fast Fourier transform and a narrow line-width laser, we demonstrate sub-MHz resolution with a measurement speed bounded by the theoretical limit.
Drug‐eluting stent coatings (2009)

This paper reviews the development of coronary stents from a polymer scientist's view point, and presents the first results of an interdisciplinary team assembled for the development of new stent systems. Poly(styrene-b-isobutylene-b-styrene) block copolymer (SIBS), a nanostructured thermoplastic elastomer, is used in clinical practice as the drug-eluting polymeric coating on the Taxus coronary stent (trademark of Boston Scientific Co.). Our group has been developing new architectures comprising of arborescent (dendritic) polyisobutylene cores (D_SIBS), which were shown to be as biocompatible as SIBS. ElectroNanospray (Nanocopoeia Inc.) was used to coat test coupons and coronary stents with selected D(S)IBS polymers loaded with dexamethasone, a model drug. The surface topology varied from smooth to nanosized particulate coating. This paper will demonstrate how drug release profiles were influenced by both the molecular weight of the polyisobutylene core and spraying conditions of the polymer-drug mixture.