gebhart/patrepeval huggingface dataset:
Adoption Issues in DevOps from the Perspective of Continuous Delivery Pipeline (2019)

DevOps and Continuous Delivery (CD) are the terms that are always related to each other in Software Delivery and Operation Process area. DevOps introduces a significant agile perspective to deliver the software product in short cycle time that will reduce technical debt that is caused by delay. Continuous Delivery is one of the DevOps' practices that enables software organization to release new features and new products rapidly. However, the correct practices are still in ambiguity to the current CD process. This paper investigates the advantages and limitation of DevOps adoption to improve the CD process. A qualitative web survey has been conducted to identify the DevOps and Continuous Delivery advantages and adoption problems. 13 respondents' feedbacks have been collected and analyzed. Based on the survey, there are four significant DevOps' practices that need to be considered and developed as a proper guideline to introduce to practitioners.
Syntheses and <sup>1</sup>H NMR Spectroscopy of Rigid, Cofacially Aligned, Porphyrin−Bridge−Quinone Systems in Which the Interplanar Separations between the Porphyrin, Aromatic Bridge, and Quinone Are Less than the Sum of Their Respective van der Waals Radii (2000)

Unusually rigid π-stacked porphyrin−spacer−quinone systems have been synthesized using an approach that enables extensive control over the nature of electronic interactions between donor, aromatic spacer, and acceptor. This new class of porphyrin-based structures is distinct from related assemblies designed to probe electronic interactions between cofacial π-stacked, aromatics: the donor (D), spacer (Sp), and acceptor (A) components of the assembly are held fixed at sub van der Waals contact distances, restricting severely the range of dynamical processes that modulate typically the magnitude of inter-ring separation and the extent of the lateral shift between juxtaposed aromatic units in the condensed phase. NMR spectroscopic studies demonstrate that these structures manifest disparate shielding environments which distribute uniformly the aromatic 1H resonances for these diamagnetic D−Sp−A compounds over spectral windows that exceed 9.0 ppm.
Energy Conservation Associated with Ethanol Formation from H <sub>2</sub> and CO <sub>2</sub> in Clostridium autoethanogenum Involving Electron Bifurcation (2015)

Ethanol formation from syngas (H2, CO, and CO2) and from H2 and CO2 that is catalyzed by bacteria is presently a much-discussed process for sustainable production of biofuels. Although the process is already in use, its biochemistry is only incompletely understood. The most pertinent question is how the bacteria conserve energy for growth during ethanol formation from H2 and CO2, considering that acetyl coenzyme A (acetyl-CoA), is an intermediate. Can reduction of the activated acetic acid to ethanol with H2 be coupled with the phosphorylation of ADP? Evidence is presented that this is indeed possible, via both substrate-level phosphorylation and electron transport phosphorylation. In the case of substrate-level phosphorylation, acetyl-CoA reduction to ethanol proceeds via free acetic acid involving acetaldehyde:ferredoxin oxidoreductase (carboxylate reductase).
Inflammation and Bone Loss in Periodontal Disease (2008)

Inflammation and bone loss are hallmarks of periodontal disease (PD). The question is how the former leads to the latter. Accumulated evidence demonstrates that PD involves bacterially derived factors and antigens that stimulate a local inflammatory reaction and activation of the innate immune system. Proinflammatory molecules and cytokine networks play essential roles in this process. Interleukin-1 and tumor necrosis factor-alpha seem to be primary molecules that, in turn, influence cells in the lesion. Antigen-stimulated lymphocytes (B and T cells) also seem to be important. Eventually, a cascade of events leads to osteoclastogenesis and subsequent bone loss via the receptor activator of nuclear factor-kappa B (RANK)-RANK ligand (RANKL)-osteoprotegerin (OPG) axis. This axis and its regulation are not unique to PD but rather are critical for pathologic lesions involving chronic inflammation. Multiple lines of evidence in models of PD clearly indicate that increases in RANKL mRNA expression and protein production increase the RANKL/OPG ratio and stimulate the differentiation of macrophage precursor cells into osteoclasts. They also stimulate the maturation and survival of the osteoclast, leading to bone loss. OPG mRNA expression and protein production do not generally seem to be increased in the periodontitis lesion. Studies of RANKL and OPG transgenic and knockout animals provide further support for the involvement of these molecules in the tissue loss observed in PD. Ironically, periodontal practitioners have focused on the bacterial etiology of PD and believed that plaque removal was aimed at eliminating specific bacteria or bacterial complexes. However, it seems that the reduction of inflammation and attenuation of the host's immune reaction to the microbial plaque, eventually leading to a decrease in the ratio of RANKL/OPG and a decrease in associated bone loss, are the actual and desired outcomes of periodontal therapy. Future therapeutic options are likely to have regulation of the RANK-RANKL-OPG axis as their goal.
Electron tunneling and superconductivity (1974)

Work on tunneling between superconductors is discussed and some experimental results are given. 2 refs.
Transforming growth factor beta-1 and beta-2 in human tear fluid (1996)

The results of these studies indicate that TGF-beta1 and TGF-beta2 are present in human tear fluid, and TGF-beta1 is the predominant isoform. There appear to be factors in human tears capable of binding TGF-beta.
Agent-based Simulation Platforms: Review and Development Recommendations (2006)

Five software platforms for scientific agent-based models (ABMs) were reviewed by implementing example models in each. NetLogo is the highest-level platform, providing a simple yet powerful programming language, built-in graphical interfaces, and comprehensive documentation. It is designed primarily for ABMs of mobile individuals with local interactions in a grid space, but not necessarily clumsy for others. NetLogo is highly recommended, even for prototyping complex models. MASON, Repast, and Swarm are “framework and library” platforms, providing a conceptual framework for organizing and designing ABMs and corresponding software libraries. MASON is least mature and designed with execution speed a high priority. The Objective-C version of Swarm is the most mature library platform and is stable and well organized. Objective-C seems more natural than Java for ABMs but weak error-handling and the lack of developer tools are drawbacks. Java Swarm allows Swarm’s Objective-C libraries to be called from Java; it does not seem to combine the advantages of the two languages well. Repast provides Swarm-like functions in a Java library and is a good choice for many, but parts of its organization and design could be improved. A rough comparison of execution speed found MASON and Repast usually fastest (MASON 1-35% faster than Repast), Swarm (including Objective-C) fastest for simple models but slowest for complex ones, and NetLogo intermediate. Recommendations include completing the documentation (for all platforms except NetLogo), strengthening conceptual frameworks, providing better tools for statistical output and automating simulation experiments, simplifying common tasks, and researching technologies for understanding how simulation results arise.
Randomized comparison between Ramp and Burst+ atrial antitachycardia pacing therapies in patients suffering from sinus node disease and atrial fibrillation and implanted with a DDDRP device (2006)

In patients suffering from SND and AT, Ramp therapy shows higher termination efficacy than Burst+ therapy in AT episodes with ATCL >240 ms. Further studies are required to show the impact of ATP on clinical outcomes.
Comparison of Corrosion Rate-Measuring Devices for Determining Corrosion Rate of Steel-in-Concrete Systems (1992)

The principles of the various corrosion rate-measuring instruments (3LP, Nippon Steel Company, and GECOR devices) are presented. The corrosion rate determined by these devices is compared with that obtained by standard electrochemical and nonelectrochemical corrosion rate-measuring methods. For corroding steel coupons in acid, very good agreement was found between the electrochemical and nonelectrochemical rate-determining systems, but for passive specimens, the agreement was not so good. A linear relationship was observed between the results obtained by the Nippon device and impedance spectroscopy for small mortar specimens irrespective of the test solution, exposure to solution, or test cycle. The significance of this relationship is discussed. Testing of large concrete specimens shows that for passive steel-in-concrete systems, all devices were incapable of confining the signal distribution from the counter electrode to the rebar area directly below the counter electrode when the size of the working electrode far exceeded that of the counter electrode. This may be due to either the inherent difficulty in confining signal distribution in a passive steel-in-concrete system or the small size of the counter electrode used. However, for an active system, the confinement achieved resulted in calculated Rp values that are much closer to the actual average rate.
Phenylboronic acid is a more potent inhibitor than boric acid of key signaling networks involved in cancer cell migration (2011)

Previous studies from our lab have shown that both boric (BA) and phenylboronic- acid (PBA) inhibit the migration of prostate cancer cell lines, as well as non-tumorigenic prostate cells. Our results indicate that PBA is more potent than BA in targeting metastatic and proliferative properties of cancer cells. Here we focus on the impact of BA and PBA on Rho family of GTP-binding proteins and their downstream targets. Treatment with 1mM PBA and BA decreases activities of RhoA, Rac1, and Cdc42 in DU-145 metastatic prostate cancer cells, but not in normal RWPE-1 prostate cells. Furthermore, ROCKII activity and phosphorylation of myosin light chain kinase decrease as a result of either PBA or BA treatment in DU-145 cells, suggesting these compounds target actomyosin-based contractility.
Photosensitive Materials on a Base of Polysiloxane for the Alignment of Nematic Liquid Crystals (1997)

The light-induced alignment of a number of commercial liquid crystals (LC) on the surface of photosensitive polysiloxane based polymers was studied. It was shown that the materials can provide thermostable homeotropic, planar and tilted alignments of good quality. The value of tilt angle depends upon the LC material, irradiation intensity and exposure as well as aligning film thickness and temperature treatment.
nippon kagaku kaishi (1977)

ホトク律ミックベンゾスピラン化合物を可逆特性をもつ画燥記録媒体に応用するためには光発色状態の安定性を制御することが重要である。そしてホトクロミヅク金属キレートの形成ほ発色種の寿命延長のために有効である。従来6-位にニトPt,8-位にメトキシル基をもつペンゾスピラン化合物(1ノ,3'-ジヒドm-1ノ,3',3t-トリメチルー6-ニトロー8-メトキシスピロ[2H-1-ベンゾピランー2,2'-[2H]インドール],SP-2とする)の溶液中における金属キレート形成は確認されていなかった。本報告ではSP-2とCu(III)イオンの塩化水素を含んだ無極性溶媒(テトラヒドロフラン)中における光キレート反応を論ずる。SP-2,銅IDアセチルアセトンキレートCu(acac)2コおよびHCIからなる試料溶液を光照射すると無色から青ないしマゼンタ色が現われる。これは2種の発色化合物,単純なSP-2の開環発色種[A]:青色(λ=600nm)とSP-2と[Cu(acac)2]との間の生成物([B],マゼンタ(λ=510nm))め混成によるものである。これらの発色種は熱的に消失し,消色過程は-次反応である。そして2種の生成物のうちこBは安定でその-次反応速度定数は室温で[A]の1!5程度であった。試料中のHCl含有量を増すとHCI/[Cu(acac)]=3.7(モル比)で発色種は二つから[B]のみにすることができる。そして試料中における[Cu(acac)2]の含有量と[B]の吸光度の関係から,吸光度の極大値はSP-2ノ[Cu(acac)]ニ2(モル比)で現われると見積れ跨。以上の結果,光発色種[B]は金属キレートであり,SP-2とCu(1)イオンの結合比は2であるとすることができる。またキレート化は2段階で行なわれると考えられ,最初SP-2は光化学的に開環発色種[A]になり,引きっづきそれがキレートである[Cu(acac)2]との間で配位子交換的にCu(III)イオンを引き抜くように反応してマゼンタ色の[B]となる。塩化水素の寄与は重要であり二つの効果を現わすと考えられる。-つはキレートを塩化物として安定化させることであり,他は酸性雰囲気を醸成してキレート形成反応を促進することであろう。
Full Color Display With Amorphous Silicon Pin Diodes For High Performance Applications (1989)

This paper presents the recent developments in our Active Matrix Liquid Crystal Displays for military, avionic and automotive applications. Data is presented for PIN diode driven active matrix liquid crystal display, with full color and high resolution (164 lines per inch). Optimization of color coordinates versus transmission has led us to better overall display performance. The contrast ratios were measured for various viewing angles (+/-60H and +45,-15 V) at different temperatures (-54 C to +85 C). The display shows good high ambient contrast ratio both by theoretical model and experimentally. The discrimination index model is used together with measurements to get the index for different high ambient light levels.
Transinformation for active object recognition (2002)

This article develops an analogy between object recognition and the transmission of information through a channel based on the statistical representation of the appearances of 3D objects. This analogy provides a means to quantitatively evaluate the contribution of individual receptive field vectors, and to predict the performance of the object recognition process. Transinformation also provides a quantitative measure of the discrimination provided by each viewpoint, thus permitting the determination of the most discriminant viewpoints. As an application, the article develops an active object recognition algorithm which is able to resolve ambiguities inherent in a single-view recognition algorithm.
Predominant expression of type-VI adenylate cyclase in C6-2B rat glioma cells may account for inhibition of cyclic AMP accumulation by calcium (1993)

In C6-2B cells, agonist-stimulated cyclic AMP accumulation is inhibited when the cytosolic Ca2+ concentration is increased. We now demonstrate that in C6-2B cells: (i) the early kinetics of the cyclic AMP inhibition by substance K (t1/2 = 35 s) and thapsigargin (t1/2 = 1.6 min) closely mimic the kinetics of the cytosolic Ca2+ increase evoked by either agent (t1/2 = 25 s and 1.5 min respectively); (ii) the Ca2+ rise and cyclic AMP inhibition by substance K or thapsigargin are similarly affected in EGTA-containing medium; (iii) PCR detects type-III and type-VI adenylate cyclase cDNAs, and RNAase protection assays show that the mRNA for type-VI adenylate cyclase, an isoform inhibitable by submicromolar Ca2+ concentrations, is the predominant species, strongly suggesting that type-VI adenylate cyclase is probably the target molecule for Ca(2+)-mediated inhibition of cyclic AMP accumulation.
Assessment: Botulinum neurotoxin in the treatment of autonomic disorders and pain (an evidence-based review) [RETIRED] (2008)

Botulinum neurotoxin (BoNT) should be offered as a treatment option for the treatment of axillary hyperhidrosis and detrusor overactivity (Level A), should be considered for palmar hyperhidrosis, drooling, and detrusor sphincter dyssynergia after spinal cord injury (Level B), and may be considered for gustatory sweating and low back pain (Level C). BoNT is probably ineffective in episodic migraine and chronic tension-type headache (Level B). There is presently no consistent or strong evidence to permit drawing conclusions on the efficacy of BoNT in chronic daily headache (mainly transformed migraine) (Level U). While clinicians' practice may suggest stronger recommendations in some of these indications, evidence-based conclusions are limited by the availability of data.
Technoeconomic Analysis of Photoelectrochemical (PEC) Hydrogen Production (2009)

This report documents the engineering and cost characteristics of four PEC hydrogen production systems selected by DOE to represent canonical embodiments of future systems.
A boron nitride scintillation converter for neutron radiography (1984)

The high sensitivity of fluorescent converters is important if one is to successfully use neutron sources that are not as strong as those of nuclear reactors. New fluorescent converters made of boron nitride (BN) were fabricated and tested. The sensitivity of the BN converter remains about 1/20 that of the NE426, a commonly used Nuclear Enterprises Scintillator, but the image quality is superior. Good quality neutron radiographs and neutron television images have been obtained with the new converters.
The Coordination Chemistry of DNA Nucleosides on Gold Nanoparticles as a Probe by SERS (2002)

The DNA nucleosides(dA, dC, dG, dT)bound to gold nanoparticles (~13 nm) in aqueous solution has been studied as a probe by the SERS and their coordination structures have been proposed on the basis of them. According to UV-Visible absorption of gold nanoparticles after modifying with DNA nucleosides, the rates of absorption of dA, dC, and dG were much faster than that of dT as monitored by the aggregation kinetics at 700 nm. These data indicated that the nucleosides dA, dC, and dG had a higher affinity for the gold nanoparticles surface than nucleoside dT. As the result of SERS spectra, the binding modes of each of the nucleosides on gold nanoparticles have been assigned. A dA binds to gold nanoparticles via a N(7) nitrogen atom of the imidazole ring, which the C(6)-<TEX>$NH_2$</TEX> group also participates in the coordination process. In the case of dC, it binds to the gold surface via a N(3) nitrogen atom of the pyrimidine ring with a partial contribution from the oxygen of C(2)=O group. A coordination of dG to the gold surfaces is also proposed. Although the dG has the two different nitrogens of a pyrimidine ring and the amino group, the N(1) nitrogen atom of a pyrimidine ring has a higher affinity after the hydrogen migrates to the amino group. Conversely, dT binds via the oxygen of the C(4)=O group of the pyrimidine ring. Accordingly, these data suggest that the nitrogen atom of the imidazole or the pyrimidine ring in the DNA nucleosides will bind more fast to the gold nanoparticles surfaces than the oxygen atom of the carbonyl group.
THE EFFECT OF <i>X</i>‐IRRADIATION ON THE RESPONSE OF THE INTESTINE TO ACETYLCHOLINE AND ON ITS CONTENT OF “PSEUDO”‐CHOLINESTERASE (1952)

Recently an investigation was published of the effect of x-irradiation on the pressor amines in the adrenal medulla In the course of this work the effect of x-irradiation in causing changes in the intes- tine was noted. The rats suffered from diarrhoea, which indicated increased motility of the intestines, while, on the other hand, when the rats were killed at the end of 72 hr., the lower bowel appeared to be distended and flaccid. We decided to investigate the response of isolated loops of intestine taken from rats after irradiation in order to see if there was any change in their contractile response to acetylcholine and to histamine. We now describe this work in which we found that isolated loops of intestine show changes in response to the stimulant action of acetylcholine after irradiation, but not in response to histamine. Since the effects observed might be due to a change in the amount of cholinesterase, we made determinations of the amounts of this enzyme, and found changes in this also. METHODS Irradiation of the rats.-Male albino rats from an inbred laboratory stock were irradiated singly or in pairs in an aluminium box. Treatment factors were 240 kv. 15m. amp. H.V.L. 1.14 mm. Cu; tube distance 70 cm., dose rate 42 r./min. The field was uniform to + 3 per cent. Total dose 1,000 r. The rats weighed from 250 to 350 g., and were usually litter mates.
Characterization of a Transitional Preplasmablast Population in the Process of Human B Cell to Plasma Cell Differentiation (2011)

The early steps of differentiation of human B cells into plasma cells are poorly known. We report a transitional population of CD20(low/-)CD38(-) preplasmablasts along differentiation of human memory B cells into plasma cells in vitro. Preplasmablasts lack documented B cell or plasma cell (CD20, CD38, and CD138) markers, express CD30 and IL-6R, and secrete Igs at a weaker level than do plasmablasts or plasma cells. These preplasmablasts further differentiate into CD20(-)CD38(high)CD138(-) plasmablasts and then CD20(-)CD38(high)CD138(+) plasma cells. Preplasmablasts were fully characterized in terms of whole genome transcriptome profiling and phenotype. Preplasmablasts coexpress B and plasma cell transcription factors, but at a reduced level compared with B cells, plasmablasts, or plasma cells. They express the unspliced form of XBP1 mRNA mainly, whereas plasmablasts and plasma cells express essentially the spliced form. An in vivo counterpart (CD19(+)CD20(low/-)CD38(-)IL-6R(+) cells) of in vitro-generated preplasmablasts could be detected in human lymph nodes (0.06% of CD19(+) cells) and tonsils (0.05% of CD19(+) cells). An open access "B to Plasma Cell Atlas," which makes it possible to interrogate gene expression in the process of B cell to plasma cell differentiation, is provided. Taken together, our findings show the existence of a transitional preplasmablast population using an in vitro model of plasma cell generation and of its in vivo counterpart in various lymphoid tissues.
Projecting Individualized Absolute Invasive Breast Cancer Risk in Asian and Pacific Islander American Women (2011)

The AABCS model was calibrated to ethnicity-specific incidence rates from the SEER program for projecting absolute invasive breast cancer risk and is preferable to BCRAT for counseling APA women.
Closure of random elastic surfaces in contact (1985)

The physical contact between two rough surfaces is referred to as a “joint,” and the deformation of such a joint under normal stress is called the “joint closure.” Toward better understanding of joint closure, we present a theory of contact between two random nominally flat elastic surfaces. This theory is a more general form of a theory presented previously by others for the elastic contact of a rough surface and a flat surface. In agreement with the previous theory we show that the joint closure property depends as much on the details of the surface topography as on the elastic properties of the material. To apply these results by using linear surface profiles requires mapping of profile information to three dimensions. The mapping techniques described here require the probability density function for the contacting surfaces to be approximated well by either a Gaussian distribution or an inverted chi‐square distribution. Laboratory experiments on ground surfaces of glass samples were done to test the theory. Both joint closure and surface topography were measured. In most cases, experimental results agreed quantitatively with predictions of the theory. However, in experiments on the smoothest surfaces, sample preparation problems often resulted in surfaces with a domed shape. These surfaces did not fit the assumptions of the theory, but the observed deviations from the theory were consistent with this domed shape. Surface topography measurements suggest that many surfaces are statistically similar. This implies that the success of the theory in predicting joint closure does not depend on a particular sample preparation technique. Therefore the theory should be valid for all nominally flat elastic surfaces. The form of the power spectrum implies that the surface topography and thus the joint closure depend on sample size.
Die Rolle der Hydrothermalsynthese in der präparativen Chemie (1985)

Unter Hydrothermalsynthesen versteht man heute heterogene Reaktionen in wäßrigem Medium oberhalb 100°C und 1 bar. Die früher übliche Unterscheidung zwischen hydrothermalen und pneumatolytischen Bedingungen (unterhalb bzw. oberhalb des kritischen Punktes) wird nicht mehr gemacht, da beim überschreiten kritischer Punkte keine Diskontinuitäten beobachtet werden. Unter hydrothermalen Bedingungen gehen sonst schwerlösliche Stoffe als Komplexe in Lösung, an deren Bildung Wasser selbst oder gut lösliche „Mineralisatoren”︁ beteiligt sein können. Dabei gelten die Gesetzmäßigkeiten chemischer Transportreaktionen, als deren Spezialfall die Hydrothermalsynthese angesehen werden kann. In den letzten Dekaden hat die Methode in den Geowissenschaften – in denen sie auch historisch angesiedelt ist – starke Impulse erfahren, deren übertragung auf die präparative Festkörperchemie diskutiert wird.