gebhart/patrepeval huggingface dataset:
[Identification of digital differential expression patterns of a novel human gene (UBAP1) by an expressed sequence tag strategy]. (2002)

The authors present an EST approach that proved to be useful for the identification of differential expression patterns of ubap1 in different tumors. These findings could be valuable for the investigation of the mechanism of UBAP1 gene exhibiting differential expression, potentially involved in the progression of multiple cancers.
Pharmacokinetics of Inhaled Liposome-encapsulated Fentanyl (1995)

The data suggest that this analgesic method offers a simple and noninvasive route of administration with a rapid increase of Cfen and a prolonged therapeutic fentanyl concentration. Future studies are required to determine the optimal liposome composition that would produce a sustained stable Cfen within analgesic therapeutic concentrations.
Competitive adsorption and state of charge of halide ions in monolayer oxide film growth processes at Pt anodes (1981)

The competitive electrodeposition of the monolayer of surface oxide on Pt electrodes is studied in the presence of co-adsorbed halide ions (X–= Cl–, Br–, I–), down to very low concentrations. These experiments give information essential to the understanding of the state of the surface of Pt anodes at which halogen evolution is occurring from aqueous halide ion solutions and hence provide a basis for interpretation of the kinetics of, and electrocatalysis in, anodic evolution of halogens, especially Cl2. The isotherms for competitive electrochemical adsorption of OH and O species in the surface oxide film, relative to that of X– ions, are evaluated quantitatively.Cl– selectively blocks the initially deposited OH monolayer at Pt while Br– and I– block the formation of the surface oxide non-selectively over a wide potential range, indicating a difference of the state of charge (‘electrosorption valency’) of adsorbed Br– and I–, in relation to that of adsorbed Cl–. This is confirmed by the forms of the competitive adsorption isotherms: Cl– gives linear-logarithmic behaviour in [Cl–], indicating strong lateral interactions, while Br– and I– effects conform more to Langmuir behaviour.A method for quantitatively treating the competitive adsorption, giving information on lateral interaction effects in the surface oxide film with co-adsorbed X– ions, is given in terms of a ‘differentiated’ adsorption isotherm function.
The Tera project: a hybrid queueing ATM switch architecture for LAN (1995)

The Tera ATM LAN project at Carnegie Mellon University addresses the interconnection of hundreds of workstations in the Electrical and Computer Engineering Department via an ATM-based network. The Tera network architecture consists of switched Ethernet clusters that are interconnected using an ATM network. This paper presents the Tera network architecture, including an Ethernet/ATM network interface, the Tera ATM switch, and its performance analysis. The Tera switch architecture for asynchronous transfer mode (ATM) local area networks (LAN's) incorporates a scalable nonblocking switching element with hybrid queueing discipline. The hybrid queueing strategy includes a global first-in first-out (FIFO) queue that is shared by all switch inputs and dedicated output queues with small speedup. Due to hybrid queueing, switch performance is comparable to output queueing switches. The shared input queue design is scalable since it is based on a Banyan network and N FIFO memories. The Tera switch incorporates an optimal throughput multicast stage that is also based on a Banyan network. Switch performance is evaluated using queueing analysis and simulation under various traffic patterns.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The Basic Principles of Super-Regenerative Reception (1938)

By means of cathode-ray oscillograms and mathematical analyses the principal phenomena occurring in superregenerative receivers are explained. The results verify an earlier theory that in the separately quenched detector the received signal merely causes the detector to oscillate at maximum output for a longer period during each quench cycle, without increasing the maximum amplitude of the oscillations. It is also shown that in the self-quenched detector the signal merely produces an increase in the quench frequency, without increasing the maximum amplitude reached by the oscillations. The sensitivity, selectivity, and characteristic noise of superregenerative receivers are discussed.
Analysis Of Web User Identification Methods (2007)

Web usage mining has become a popular research area, as a huge amount of data is available online. These data can be used for several purposes, such as web personalization, web structure enhancement, web navigation prediction etc. However, the raw log files are not directly usable; they have to be preprocessed in order to transform them into a suitable format for different data mining tasks. One of the key issues in the preprocessing phase is to identify web users. Identifying users based on web log files is not a straightforward problem, thus various methods have been developed. There are several difficulties that have to be overcome, such as client side caching, changing and shared IP addresses and so on. This paper presents three different methods for identifying web users. Two of them are the most commonly used methods in web log mining systems, whereas the third on is our novel approach that uses a complex cookie-based method to identify web users. Furthermore we also take steps towards identifying the individuals behind the impersonal web users. To demonstrate the efficiency of the new method we developed an implementation called Web Activity Tracking (WAT) system that aims at a more precise distinction of web users based on log data. We present some statistical analysis created by the WAT on real data about the behavior of the Hungarian web users and a comprehensive analysis and comparison of the three methods
Suppression of immediate and late responses to antigen by a non‐anaphylactogenic anti‐IgE antibody in a murine model of asthma (1999)

Eosinophils are recruited to the airways during allergic reactions, but animal models have shown that their mere presence is not sufficient for the development of bronchopulmonary hyperreactivity. Other factors, such as immunoglobulin (Ig)E, seem to be required. Using mice selected for the production of large amounts of IgE, the effects of antibody neutralization of IgE on antigen-induced lung recruitment of eosinophils and induction of bronchopulmonary hyperreactivity and of other indicators of inflammation were studied. A monoclonal non-anaphylactogenic rat anti-mouse IgE (mAb1-5), given within 24 h of the challenge with antigen, reduced tissue eosinophilia, the recruitment of IgE-bearing cells identified as basophils, mucous cell metaplasia, anaphylactic bronchoconstriction and bronchopulmonary hyperreactivity. mAb1-5 inhibited interleukin (IL)4 titres in the bronchoalveolar lavage fluid, but not those of I1-5. Inhibition by mAb1-5 may result from competitive displacement of immunoglobulin E from its different receptors, thus preventing cell stimulation. Moreover, the inhibition of the massive recruitment of immunoglobulin E-bearing basophils into the lungs within hours after challenge and of interleukin4 production by mAb1-5 may be important factors leading to the reduction of pulmonary eosinophilia and bronchopulmonary hyperreactivity. Thus, immunoglobulin (Ig)E and allergic IgE-bearing cells seem to play an essential role in the initial development of the late allergic airway responses.
Molecular pathology of endometrial carcinoma: practical aspects from the diagnostic and therapeutic viewpoints (2008)

This article reviews the main molecular alterations involved in endometrial carcinoma. Five molecular features (microsatellite instability, and mutations in the PTEN, k-RAS, PIK3CA and beta-catenin genes) are characteristic of endometrioid carcinomas, whereas non-endometrioid carcinomas show alterations of p53, loss of heterozygosity (LOH) on several chromosomes, as well as other molecular alterations (STK15, p16, E-cadherin and C-erb B2). The review also covers the phenomenon of apoptosis resistance, as well as the results obtained from cDNA array studies, and the perspectives for targeted therapies. A group of practical applications of molecular pathology techniques are also mentioned: diagnosis of hereditary non-polyposis colon cancer syndrome in patients with endometrial carcinoma; evaluation of precursor lesions; prognosis; diagnosis, particularly for synchronous endometrioid carcinomas of the uterus and the ovaries; and targeted therapies.
A Flexible Approach for the Calibration of Biplanar Radiography of the Spine on Conventional Radiological Systems (2010)

This paper presents a new method for the calibration of biplanar radiography that makes possible performing 3D reconstructions of the spine using conventional radiological systems. A novel approach is proposed in which a measuring device is used for determining focal distance and have a rough estimation of translation parameters. Using these data, 3D reconstructions of the spine with correct scale were successfully obtained without the need of calibration objects, something that was not previously achieved. For superior results, two optional steps may be executed that involve an optimisation of the geometrical parameters, followed by a scale adjustment with a very simple calibration object. Computer simulations with in vivo CT data show RMS 3D reconstruction errors of 1.9 mm when under the maximum expected variation of the geometrical parameters of the radiological system. Simulations also show that the 3D spinal length may be accurately calculated, but with superior results when using optimisation and adjusting scale (RMS error of 2.09 mm). In vitro experiments with a dried spine composed by 17 vertebrae show mean 3D reconstructions errors of 1.7 mm. We conclude that the proposed method is suitable for use in clinical environment, and that it compares favourably with previous calibration techniques.
Ionic liquids as novel materials for energy efficient CO2 separations (2012)

Large improvements in separations technology will require novel materials with enhanced properties and performance. The fundamental interlinks for success in merging synthesis and process incorporation are the structure, relevant physical/chemical properties, and performance of new materials. Specific materials with these interlinks are room-temperature ionic liquids (RTILs) and their polymers and composites. As a chemical platform, RTILs have an enormous range of structural variation that can provide the ability to “tune” their properties and morphology for a given application. Introduction of chemical specificity into the structure of RTIL-based materials is an additional key component. Membrane separation is the focus as a process for implementation. There have not been new materials successfully developed for this process in thirty years. For CO 2 capture, the target improvement in productivity is two orders of magnitude or more compared to commercial materials currently available.
A defect in the inflammation-primed macrophage-activation cascade in osteopetrotic rats. (1994)

Macrophages were activated by administration of lysophosphatidylcholine (lyso-Pc) or dodecylglycerol (DDG) to wild-type rats but not in osteopetrotic (op) mutant rats. In vitro treatment of wild-type rat peritoneal cells with lyso-Pc or DDG efficiently activated macrophages whereas treatment of op mutant rat peritoneal cells with lyso-Pc or DDG did not activate macrophages. The inflammation-primed macrophage activation cascade in rats requires participation of B lymphocytes and vitamin D binding protein (DBP). Lyso-Pc-inducible beta-galactosidase of wild-type rat B lymphocytes can convert DBP to the macrophage-activating factor (MAF), whereas B lymphocytes of the op mutant rats were shown to be deficient in lyso-Pc-inducible beta-galactosidase. DBP is conserved among mammalian species. Treatment of human DBP (Gc1 protein) with commercial glycosidases yields an extremely high titrated MAF as assayed on mouse and rat macrophages. Because the enzymatically generated MAF (GcMAF) bypasses the role of lymphocytes in macrophage activation, the op mutant rat macrophages were efficiently activated by administration of a small quantity (100 pg/rat) of GcMAF. Likewise, in vitro treatment of op rat peritoneal cells with as little as 40 pg GcMAF/ml activated macrophages.
Conducting polypyrrole composite thin films chemically prepared by spreading on surface of aqueous solution containing oxidizing agent (1988)

Abstract Polypyrrole–PMMA composite films have been prepared with the chemical oxidative polymerization by spreading the water‐insoluble solvent solution of pyrrole and PMMA mixture on the surface of the aqueous solution containing K 2 S 2 O 8 , the oxidizing agent. The conductivity of the films increases rapidly, passes through a plateau, and then decreases gradually as the reaction time increases. The conductivity of the oxidized side of the film is higher by over 1 order of magnitude than that of the evaporated side. It is due to the fact that the former is rich in polypyrrole while the latter is rich in PMMA. The thickness of the films can be controlled by adjusting the PMMA concentration. However, the lower limit of the film thickness is practically in submicron order. The relationship between the transmittance and the logarithm of the conductivity of the films gives a straight line with a gradient, ca. −8. The conductivity of the films is stable on silicagels in a desiccator over 2000 h at 25°C. The conductivity of the film is, however, very sensitive to the moisture in atmosphere and gives rise to decrease with humidity.
A Survey of Flow Cytometry Data Analysis Methods (2009)

Flow cytometry (FCM) is widely used in health research and in treatment for a variety of tasks, such as in the diagnosis and monitoring of leukemia and lymphoma patients, providing the counts of helper-T lymphocytes needed to monitor the course and treatment of HIV infection, the evaluation of peripheral blood hematopoietic stem cell grafts, and many other diseases. In practice, FCM data analysis is performed manually, a process that requires an inordinate amount of time and is error-prone, nonreproducible, nonstandardized, and not open for re-evaluation, making it the most limiting aspect of this technology. This paper reviews state-of-the-art FCM data analysis approaches using a framework introduced to report each of the components in a data analysis pipeline. Current challenges and possible future directions in developing fully automated FCM data analysis tools are also outlined.
Simulation of Graphene Nanoribbon Field-Effect Transistors (2007)

We present an atomistic 3-D simulation of graphene nanoribbon field-effect transistors (GNR-FETs), based on the self consistent solution of the 3-D Poisson and Schrodinger equations with open boundary conditions within the nonequilibrium Green's function formalism and a tight-binding Hamiltonian. With respect to carbon nanotube FETs, GNR-FETs exhibit comparable performance, reduced sensitivity to the variability of channel chirality, and similar leakage problems due to band-to-band tunneling. Acceptable transistor performance requires prohibitive effective nanoribbon width of 1-2 nm and atomistic precision that could in principle be obtained with periodic etch patterns or stress patterns.
Shc Regulates Epidermal Growth Factor-induced Activation of the JNK Signaling Pathway (1999)

Two adaptor molecules, Grb2 and Shc, have been implicated in the extracellular signal-regulated kinase (ERK) activation by receptor tyrosine kinases such as the epidermal growth factor receptor (EGFR). Here we show that the EGF-mediated ERK activation is abolished by loss of Grb2, whereas this response is not affected by loss of Shc. Conversely, the EGF-mediated c-Jun N-terminal kinase (JNK) activation is dependent on Shc, but not Grb2. These findings strongly support distinct roles for Grb2 and Shc in controlling ERK and JNK activation after EGF stimulation.
Physiological changes and digestive capabilities of newly received feedlot cattle. (1999)

Newly arrived feedlot calves undergo numerous stressors that result in 1) transient endocrine responses, 2) altered products of energy and protein metabolism, 3) changes in appetite and growth rate, 4) possible limited compromise of digestive and rumen function, and 5) a challenged immune system. The most consistent endocrine and metabolic responses to marketing, transport, and feedlot adaptation are seen with cortisol and epinephrine. In contrast to earlier work done with indirect in vitro gas production measurements, recent research has shown that the ruminal microbial population is able to effectively digest available substrate immediately following a calfs weaning, trucking, and 24 h of feed and water deprivation. Additionally, a period of feed and water deprivation up to 72 h coupled with 8 h of trucking does not reduce the concentration or total numbers of either the viable cellulolytic or total bacteria present in the rumen of newly weaned or feedlot-adapted calves. However, ruminal volume, DM, total weight of ruminal contents, and total protozoal numbers decrease as duration of feed deprivation increases. To compensate for the reduced DMI that occurs in the first 2 wk after arrival at the feedlot, increased nutrient density is needed to meet an animal's requirements for nutrients. Limited data suggest that newly arrived calves prefer a diet that is similar in moisture and texture to feeds with which they are familiar. Additionally, modification of the stress-associated behavior using trainer animals may improve the feed intake of newly received calves and may reduce calf morbidity.
Web-Based Media GIS Architecture Using the Virtual World Mapping Technique (2003)

In this paper, we propose web-based Media GIS architecture using 3D geographical database and GPS-related data resulted from 4S-Van. We introduce a novel interoperable geographical data service concept; so-called, Virtual World Mapping (VWM) that can map 3D graphic world with realworld video. Our proposed method can easily retrieve geographical information and attributes to reconstruct 3D virtual space according to certain frame in video sequences. 
Our proposed system architecture also has an advantage that can provide geographical information service with video stream without any image processing procedures. In addition to, describing the details of our components, we present a Media GIS web service system by using GeoVideoServer, which performs VWM technique.
Decay of Rotational Airflow with Flow Conditioner in Larger Diameter Ducts for Dust Concentration Measurement using Isokinetic Sampling (2016)

Within this study the decay speed of centrifugal device induced rotational airflow in round ducts and its conditioning for dust concentration measurement was investigated. Tests were conducted under room conditions at average Reynolds numbers within the range of 0.7–1.14x105. Duct diameters were 152 mm and 203 mm. Airflow in the ducts was found nonuniform and unsteady within the axial location to diameter ratio (x/D) of 10.5. The nonuniformity of axial airflow was nearly independent of the average Reynolds number. The study proved that it is impractical to decay the rotational airflow simply by using straight extension duct. A flow conditioner with minimal particle loss is needed to make the air flow uniform and steady. As a case study, a simple flow conditioner was tested. It decayed the rotational airflow to an acceptable level within x/D=2. The measured dust concentrations at 5 radial locations at x/D=2 were uniform: σ/µ&lt;1% for total mass concentration, and σ/µ&lt;10 % for all the particles smaller than 10 µm.
The Phytochemical Constituents of Withania Somnifera (Ashwagandha) (2015)

Withania somnifera is a well known Indian medicinal plant widely used in the treatment of many clinical conditions in India. Unani system of medicine, roots of Withania somnifera commonly known as Asgand are used for the medicinal properties. Two varieties of Asgand have been mentioned in classical Unani literatue: 1) Asgand Nagori and 2) Asgand Dakani. Asgand Nagori is preferred for its more potential medicinal properties. The roots of Withania somnifera consist primarily of compounds known as withanolides, which are believed to account for its extraordinary medicinal properties. Keywords: Ginger, Withania somnifera Asgand
Multi‐Peer Disagreement and the Preface Paradox (2014)

Abstract The problem of multi‐peer disagreement concerns the reasonable response to a situation in which you believe P 1 … P n and disagree with a group of ‘epistemic peers’ of yours, who believe ∼ P 1 … ∼ P n , respectively. However, the problem of multi‐peer disagreement is a variant on the preface paradox; because of this the problem poses no challenge to the so‐called ‘steadfast view’ in the epistemology of disagreement, on which it is sometimes reasonable to believe P in the face of peer disagreement about P . After some terminology is defined (§1), Peter van I nwagen's challenge to the steadfast view will be presented (§2). The preface paradox will then be presented and diagnosed (§3), and it will be argued that van I nwagen's challenge relies on the same principle that generates the preface paradox (§4). The reasonable response to multi‐peer disagreement will be discussed (§5), and an objection addressed (§6).
Computer Simulation of Distributed Runoff Yield and Sediment Yield in Chabagou Catchment (2008)

A distributed model for runoff yield and sediment yield in basins based on isolated storm events was developed. The model could respectively simulate space and time processes of runoff formation and sediment yield for the watersheds with various using type of land and might reflect the effect of the spatial heterogeneity of underlying surfaces and man kind activities on the runoff yield and sediment yield in watershed. Thus the model could provide technical support and scientific basis for the basin soil and water conservation measures. The model was finally calibrated and validated by measured data in the Chabagou watershed. Results show that the proposed model can reasonably simulate rainfall-runoff-sediment transport in watershed and basically reflect the runoff sediment erosion of the physical processes of the basin.