gebhart/patrepeval huggingface dataset:
On location management for personal communications networks (1996)

Personal communications services (PCS) support mobile terminals (MTs) which are free to travel within the service coverage area. In order to effectively locate an MT when a called is initiated, location management schemes are used to keep track of the locations of the MTs. The current approach to location management requires each MT to report its location to the network periodically. The location information is then stored in databases. When a call is initiated. The network determines the current location of the called MT through a database lookup and paging procedure. A currently available standard for location management is described. Research results on location management are surveyed in detail.
A Staphylococcus aureus Pore-Forming Toxin Subverts the Activity of ADAM10 to Cause Lethal Infection (2011)

Staphylococcus aureus is a major cause of human disease, responsible for half a million infections and approximately 20,000 deaths per year in the United States alone (1,2). This pathogen secretes α-hemolysin, a pore-forming cytotoxin that contributes to the pathogenesis of pneumonia (3–5). α-hemolysin injures epithelial cells by interacting with its receptor, the zinc-dependent metalloprotease ADAM10 (6). We show that mice harboring a conditional disruption of the Adam10 gene in lung epithelium are resistant to lethal pneumonia. Investigation of the molecular mechanism of toxin-receptor function revealed that α-hemolysin upregulates ADAM10 metalloprotease activity in alveolar epithelial cells, resulting in cleavage of the adherens junction protein E-cadherin. Cleavage is associated with disruption of epithelial barrier function, contributing to the pathogenesis of lethal acute lung injury. A metalloprotease inhibitor of ADAM10 prevents E-cadherin cleavage; similarly, E-cadherin proteolysis and barrier disruption is attenuated in ADAM10 knockout mice. Together, these data attest to the function of ADAM10 as the cellular receptor for α-hemolysin. The observation that Hla can usurp the metalloprotease activity of its receptor reveals a novel mechanism of pore-forming cytotoxin action in which pathologic insults are not solely the result of irreversible membrane injury, and defines ADAM10 inhibition as a strategy for disease modification.
<title>Microfabrication and application of reservoir pins for liquid transfer in biotechnology</title> (2001)

Microarraying involves laying down genetic elements onto a solid substrate for DNA analysis on a massively parallel scale. Microarrays are prepared using a pin-based robotic platform to transfer liquid samples from microtitre plates to an array pattern of dots of different liquids on the surface of glass slides where they dry to form spots diameter < 200 micrometers . This paper presents the design, materials selection, micromachining technology and performance of reservoir pins for microarraying.
Nanoparticle Technology for Drug Delivery (2006)

Nanoparticle technology for drug delivery , Nanoparticle technology for drug delivery , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی
Low-Complexity Map Channel Estimation for Mobile MIMO-OFDM Systems (2008)

This paper presents a reduced-complexity maximum a posteriori probability (MAP) channel estimator with iterative data detection for orthogonal frequency division multiplexing (OFDM) systems over mobile multiple-input multiple- output channels. The optimal MAP estimator needs to invert an NN <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> x NN <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> data-dependent matrix each in OFDM symbol interval, where N is the number of subcarriers and N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> is the number of transmit antennas. We derive an expectation maximization (EM) algorithm with low-rank approximation to avoid inverting large-size matrices, and thus drastically reduce the receiver complexity. In the iterative process, channel parameters are initially obtained by a least square (LS) estimator for temporary symbol decisions. Then, inter-carrier interference (ICI) due to fast fading is approximated and canceled. Finally, the temporary symbol decisions and the ICI-canceled received signals are processed by the EM-based MAP estimator to refine the channel state information for improved detection. The proposed scheme achieves about 2 dB gain over the LS scheme in channels with medium to high normalized Doppler shifts.
Lossy compression of quality scores in genomic data (2014)

Supplementary data are available at Bioinformatics online.
Developing a Methodology for Three-Dimensional Correlation of PET–CT Images and Whole-Mount Histopathology in Non-Small-Cell Lung Cancer (2008)

There is no one definitive method for 3D volumetric RPC in nsclc. An innovative approach to the 3D reconstruction of resected nsclc specimens incorporates agar embedding of the specimen and whole-mount digital histopathology. The reconstructions can be rigidly and manually registered to imaging modalities such as ct and pet and exported to a radiation treatment planning system.
Foreword (1972)

with Miss Marjorie Perrers Taylor on the effects of ionizing radiation on the eye.Miss Perrers
Aging Adversely Affects the Cigarette Smoke–induced Glutathione Adaptive Response in the Lung (2010)

These data suggest that the age-related maladaptive response to CS sensitizes the lung to both inflammation and oxidation potentially contributing to the development of CS-induced chronic obstructive pulmonary disease.
Differential survival of murine small and large intestinal crypts following ionizing radiation (1997)

Radiation survival curves have been obtained for crypts in the small and large intestine of male BDF1 mice using the microcolony assay. Four regions of the small intestine and three regions of the large intestine were studied. One of the major objectives was to determine the optimal conditions for the microcolony assay in the large bowel. Various times post-irradiation were studied using different approaches and threshold criteria for surviving crypts. Small, but statistically significant, differences were observed along the length of the small intestine, but no differences were observed between different regions of the large intestine. There was a marked difference (p < 0.001) in the response in the large compared with the small intestine (D0 = 291 +/- 14 compared with 151 +/- 4 cGy respectively with corresponding extrapolation numbers of 18 +/- 4 and 377 +/- 65). The use of tritiated thymidine or vincristine helped in the identification of true survivors in the large bowel, but these approaches are not necessary in the small bowel. The longer the time after irradiation that the samples were fixed the easier it was to identify survivors in the colon. However, the longer the time the more animals died. The optimum compromise in these studies was to use partial-body irradiation (abdomen only) and to sample on the fifth day after irradiation. With these criteria the mid-colon survival curve had a D0 = 274 +/- 28 cGy and an extrapolation number of 22 +/- 10. The results can be considered in relation to published data on the levels of p53 and bcl-2 expression and apoptosis in murine small and large bowel.
Improved performance of millimetre-wave impatt diodes on type-IIa diamond heatsinks (1976)

Thermal resistance and r.f. data are presented for Ka−-, V and W-band silicon double-drift impatt diodes employing diamond heatsinks. A power level of 620 mW at 7.7% efficiency has been achieved at 101 GHz.
Correlations of Vibrio fischeri bacteria test data with bioassay data for other organisms. (1998)

Linear relationships of the median lethal concentrations of several hundreds of chemicals for a variety of organisms with Vibrio fischeri median effective concentrations are investigated. Significant correlations can be developed for many aquatic species including the fishes fathead minnow, bluegill, catfish, goldfish, goldorfe, guppy, killifish, rainbow trout, sheepshead minnow, and zebrafish; the water flea Daphnia sp.; such crustaceans as Artemia sp. and Crangon sp.; the ciliate Tetrahymena pyriformis; and algae, such as Chlorella sp. These interspecies relationships can be used to estimate order-of-magnitude type toxic effects of many substances for these aquatic organisms. Highly significant relationships can be obtained when selecting compounds on a chemical basis, such as alcohols, ketones, aromatics, etc., which allow the calculation of the compounds' toxicities to the corresponding aquatic species with increased accuracy and confidence. Analogous correlations with mammalian (rat and mouse) oral, intraperitoneal, and intravenous median lethal dose (LD50) data are much weaker than those for most aquatic species. However, there are significant differences between these three routes of administration and the intravenous LD50 data show the best relationship with the Vibrio data.
Local Residual Stress near Fatigue Crack Tip (1979)

The LocaL stress lIear the tips oj Ja tigue cracks was measured with a new method oj X-ray stress measuremellt utiLiz illg the X-ray microbeam diffra ctioll technique. The method can be regarded as an improlJed sillgLe illcidellt allgLe method alld uses illformation all L attice s train aLollg the w hoLe D ebye rillg ill order to determill e the stress vaLue. The accuracy oj the stress vaLue measured by this method was Joulld to be lIeari)' the same as that oj Si1l 2 <jJ method.
Patient Responses to Ipilimumab, a Novel Immunopotentiator for Metastatic Melanoma (2011)

Advanced melanoma has defied treatment advances for several decades. Immunotherapy with high-dose interleukin-2 or interferon-α has been beneficial in some cases, but significant toxicities limit its use. Cytotoxic T-lymphocyte antigen-4 (CTLA-4) signaling switches off T-cell activation and induces immune tolerance. Inhibiting CTLA-4 prolongs the antitumor T-cell response, reversing tolerance. Ipilimumab is a first-in-class anti-CTLA-4 monoclonal antibody, currently under review by the Food and Drug Administration for pretreated melanoma. Ipilimumab has shown durable responses and manageable toxicities in a large phase 3 clinical trial in patients with advanced melanoma. Variable response patterns have been observed, including: (1) response in baseline lesions; (2) a slow, steady decline in tumor burden; (3) response after an increase in tumor burden; and (4) response in index and new lesions accompanied by the appearance of other new lesions. Although responses (1) and (2) may be captured using standard methods, atypical responses (3) and (4) would be classified as progressive disease using conventional assessments. Patients on ipilimumab may have delayed responses or durable stable disease even after apparent disease progression, therefore using new immune-related response criteria is recommended to avoid premature treatment withdrawal. This review compares and contrasts responses to ipilimumab with those after chemotherapy, and discusses treatment implications.
COMPARATIVE PERFORMANCE OF HONEYBEES (APIS MELLIFERA L.) AND BLOW FLIES (PHORMIA TERRONOVAE) IN ONION (ALLIUM CEPA L.) SEED SETTING (2011)

Effect of honeybee and blowfly pollination on onion (Allium cepa L.) seed production was studied at National Agricultural Research Centre, Islamabad. Pakistan during 2005-06. The experiment was laid out in a randomized complete block design with three treatments (caged plants with honeybee, caged plants with blow flies and caged plants without pollinators-control) and four replications each. Number of seed sets from 10 umbels, one from each replication were counted and weighed. The number of seed sets in caged plants with honeybees was maximum as compared to plants caged with blow flies and control. The same treatment also produced maximum seed weight as compared to other treatments. The results revealed that onion seed setting is dependent on insect pollination. The percentage of seed set for first treatment i.e. the plants caged with honeybees ranged from 62-93 with mean number of 80.7+0.93 (mean + SE), followed by caged plants with blow flies 51-91%, 72.16 + 1.31 (mean + SE)] and control [7-26%, 16.4 + 4.09 (mean + SE)]. The mean weight of seed produced from the plants caged with honeybees was higher (1.90 + 0.11 g) as compared to blow flies caged plants (1.55 + 0.89) and control (0.33 + 0.22). The weight analyses were significantly different in all treatments. It is concluded that honeybees visitation to the flowers is important for pollination but blow flies can be used as an alternate pollinator when honeybees are not available. However, blow flies are not feasible in commercial seed production due to high temperature during peak flowering season in seed production area whereas honeybees are feasible as they can thrive temperature over 40°C. Blow flies are equally good candidates for experimental purposes for pollination.
Disability Theology of the Resurrection: Persisting Questions and Additional Considerations – A Response to Ryan Mullins (2012)

In his recent Ars Disputandi article, ‘Some Difficulties for Amos Yong’s Disability Theology of the Resurrection,’ Ryan Mullins argues that Yong’s proposals are fundamentally misguided by Stanley Hauerwas’ dictum – which states that to ‘eliminate the disability means to eliminate the subject’ – and that therefore Yong’s disability theology of the resurrection body encounters potentially insuperable difficulties or is not sufficiently justified in the face of more traditional accounts. In response to Mullins’ criticisms, clarifications are offered with regard to both the role of Hauerwas’ notion in Yong’s theology and the theological basis for claims regarding the persistence of the marks of impairment in the resurrection body.
Inside/outside Pt nanoparticles decoration of functionalised carbon nanofibers (Pt19.2/f-CNF80.8) for sensitive non-enzymatic electrochemical glucose detection (2012)

A highly efficient and reproducible approach for effective Pt nanoparticles dispersion and excellent decoration (inside/outside) of functionalised carbon nanofibers (f-CNF) is presented. The surface morphological, compositional and structural characterisations of the synthesised Pt(19.2)/f-CNF(80.8) material were examined using transmission electron microscopy (TEM/STEM/DF-STEM), energy-dispersive X-ray spectrometry (EDS), thermogravimetric analysis (TGA/DTG), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). Cyclic voltammetry (CV) was employed in order to confirm the typical electrochemical response for Pt. The aim of the work was to improve the utility of both the supporting matrix (via the use of both inner/outer surfaces of nanofibers) and precious Pt, together with the sensitive glucose determination. TEM data indicated successful nanoparticle decoration with average Pt particle size 2.4 nm. The studies demonstrated that utilisation of the inner surface of the nanofibers, together with the modified outer surface characteristics using chemical treatment, enables excellent decoration, effective dispersion and efficient impregnation of Pt nanoparticles on carbon nanofibers. Pt(19.2)/f-CNF(80.8) exhibited excellent amperometric response (sensitivity = 22.7 μAmM(-1)cm(-2) and LoD = 0.42 μM) towards direct glucose sensing, over the range 0-10 mM glucose, in neutral conditions (pH 7.4). The improved carbon surface area for nanoparticle decoration, inner surface structure and morphology of nanofibers together with the presence of functional groups provided strong interactions and stability. These features together with the effective nanoparticle dispersion and decoration resulted in excellent catalytic response. The decorated nanoscaled material (Pt(19.2)/f-CNF(80.8)) is capable of large scale production, providing sensing capability in neutral conditions, while eliminating the temperature sensitivity, pH and lifetime issues associated with glucose enzymatic sensors and holds great promise in the quantification of glucose in real clinical samples.
Characterization of<i>Vibrio cholerae</i>aerotaxis (2007)

The ability to move toward favorable environmental conditions, called chemotaxis, is common among motile bacteria. In particular, aerotaxis has been extensively studied in Escherichia coli and was shown to be dependent on the aer and tsr genes. Three putative aer gene homologs were identified in the Vibrio cholerae genome, designated aer-1 (VC0512), aer-2 (VCA0658), and aer-3 (VCA0988). Deletion analyses indicated that only one of them, aer-2, actively mediates an aerotaxis response, as assayed in succinate soft agar plates as well as a capillary assay. Complementation studies confirmed that Aer-2 is involved in aerotaxis in V. cholerae. In addition, overexpression of aer-2 resulted in a marked increase of the aerotactic response in soft agar plates. No observable phenotypes in V. cholerae mutants deleted in the aer-1 or aer-3 genes were detected under standard aerotaxis testing conditions. Furthermore, the V. cholerae aer-1 and aer-3 genes, even when expressed from a strong independent promoter, did not produce any observable phenotypes. As found in other bacterial species, the results presented in this study indicate the presence of a secondary aerotaxis transducer in V. cholerae.
The UI Octoson — A New Class of Ultrasonic Echoscope (1977)

A combined NOMA and multiCAP scheme is proposed for capacity enhancement of 5G mobile networks and experimentally tested over a W-band millimeter-wave radio-over-fiber system. The evaluated NOMA-CAP system provides an aggregated transmission rate of 30Gbps.
Development of 3 DOF micro finger (2002)

A 3 DOF micro finger, that has pure translational motion, is proposed. The finger will be applied in the two finger micro manipulation in order to manipulate micrometer size objects dexterously. The possible configurations are considered based on the group theory. Then, the optimal configuration is proposed by taking simple machining of joint structures into account. Kinematics analysis is made in order to describe the relation between end effector and actuator displacements. The design parameters are examined by evaluating the force capability of the actuator and the work space volume. Basic experiments are made by a prototype finger module that show excellent micro motion capability.
Energy efficient device discovery for social cloud applications in 3GPP LTE-advanced networks (2014)

Recent advances in 3GPP for device-to-device (D2D) communications underlying the cellular infrastructure have revealed several benefits regarding network resource management and increased coverage. Notwithstanding these advantages, peer discovery may significant amount of device battery if devices need to constantly sense and notify each other irrespective of the application subscriptions, and the potential of establishing D2D communications. In this paper, we consider a novel social application-based discovery mechanism that enables D2D UEs to achieve significant energy consumption savings, using the concept of social cloud region. Such a cloud-based region helps UE to activate D2D discovery features only when they are close enough to other, while having same application-based interests. The engagement of cloud applications provides the means of offloading the discovery process from not only UEs but also the LTE core network. In this paper we analyze the energy consumption profiles of various discovery mechanisms using simulations. Our simulation results validate that our proposed discovery mechanism results in significant energy savings by reducing the frequency of performing discovery procedures.
Novel singly-fed rectangular microstrip patch elements for circular polarisation (2002)

This paper presents two novel types of singly-fed circularly polarised microstrip radiating elements that use multilayer substrates. The antenna elements are designed to operate in S-band with a centre frequency of 2.45 GHz. The measured impedance bandwidths (VSWR/spl les/2) are 23% and 14% while the computed 3-dB axial-ratio bandwidths are 7% and 2% respectively. Important radiation characteristics such as gain bandwidth, cross polarisation and front-to-back ratio of these elements have also been examined and compared.
A Position-Biased PageRank Algorithm for Keyphrase Extraction (2017)

Given the large amounts of online textual documents available these days, e.g., news articles and scientific papers, effective methods for extracting keyphrases, which provide a high-level topic description of a document, are greatly needed.We propose PositionRank, an unsupervised graph-based approach to keyphrase extraction that incorporates information from all positions of a word's occurrences into a biased PageRank to extract keyphrases. Our model obtains remarkable improvements in performance over strong baselines.
Aperture optimized two‐pass Kirchhoff migration (2007)

The migration aperture is a parameter often difficult to set in Kirchhoff PSDM and on which the final quality of the migrated image depends strongly. It may take a lot of tests to determine the best possible aperture for a given dataset. We propose here a method to avoid migration tests and to optimize the aperture with a spatially variable function of data. Our workflow first consists in a coarse grid PSDM where aperture is migrated as an attribute. We have developed an algorithm which uses this result to extract and interpolate an aperture zone for each final PSDM depth point. This information is then used to optimize the second fine grid final PSDM aperture. This automatic data driven aperture optimization algorithm has been successfully tested on real marine and land datasets. With no human interaction it was possible to improve the quality of the migrated images, in some cases in a very significant way.
Development Journalism in an Asian Setting: A Study of Depthnews (1993)

Asian development journalism, centered since 1967 in the Press Foundation of Asia, begins a second quarter-century with a network of over 2,500 journalists trained by the Manila-based foundation, and a regionwide development news service, Depthnews. A content analysis of Depthnews shows the original ideas of development news survive: the service has a high proportion of stories dealing with rural development, health, population, science and news of women; it also seeks non-institutional sources and subjects. By avoiding direct government ties, PFA has maintained regional press credibility, but remains a supplemental service unable to sell itself outside Asia.
ERGIC-53 and traffic in the secretory pathway (2000)

The ER-Golgi intermediate compartment (ERGIC) marker ERGIC-53 is a mannose-specific membrane lectin operating as a cargo receptor for the transport of glycoproteins from the ER to the ERGIC. Lack of functional ERGIC-53 leads to a selective defect in secretion of glycoproteins in cultured cells and to hemophilia in humans. Beyond its interest as a transport receptor, ERGIC-53 is an attractive probe for studying numerous aspects of protein trafficking in the secretory pathway, including traffic routes, mechanisms of anterograde and retrograde traffic, retention of proteins in the ER, and the function of the ERGIC. Understanding these fundamental processes of cell biology will be crucial for the elucidation and treatment of many inherited and acquired diseases, such as cystic fibrosis, Alzheimer's disease and viral infections.