gebhart/patrepeval huggingface dataset:
Reconfigurable Memristive Device Technologies (2015)

In this paper, we present a review of the state of the art in memristor technologies. Along with ionic conducting devices [i.e., conductive bridging random access memory (CBRAM)], we include phase change, and organic/organo-metallic technologies, and we review the most recent advances in oxide-based memristor technologies. We present progress on 3-D integration techniques, and we discuss the behavior of more mature memristive technologies in extreme environments.
2D <sup>1</sup>H spectroscopic imaging of the human brain at 4.1 T (1994)

A two-dimensional spectroscopic imaging sequence consisting of an inversion recovery pulse, a plane selective prefocused pulse, and a semiselective water suppression pulse has been used to create 1H spectroscopic images of the human brain with nominal voxels of 0.5 cc. Due to the excellent lipid suppression provided by the inversion recovery pulse and subsequent delay, only planar volume selection is required enabling the entire brain within the slice to be imaged without contamination from extracerebral lipids in the brain voxels. The use of a semiselective refocusing pulse for water suppression permits any echo evolution time to be used, minimizing J-modulation and T2 losses, while retaining full sensitivity in the lactate resonance. Using this sequence we have visualized the lactate elevation in the peri-infarct region about a 6-week-old stroke.
(In-)Secure messaging with the Silent Circle instant messaging protocol (2016)

Silent Text, the instant messaging application by the company Silent Circle, provides its users with end-to-end encrypted communication on the Blackphone and other smartphones. The underlying protocol, SCimp, has received many extensions during the update to version 2, but has not been subjected to critical review from the cryptographic community. In this paper, we analyze both the design and implementation of SCimp by inspection of the documentation (to the extent it exists) and code. Many of the security properties of SCimp version 1 are found to be secure, however many of the extensions contain vulnerabilities and the implementation contains bugs that affect the overall security. These problems were fed back to the SCimp maintainers and some bugs were fixed in the code base. In September 2015, Silent Circle replaced SCimp with a new protocol based on the Signal Protocol.
Towards knowledge-customer centered services? (2007)

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
A novel high-voltage LDMOS with shielding-contact structure for HCl SOA enhancement (2017)

This paper demonstrated a novel LDMOS with gate-connected shielding-contact structure, no extra mask or process is needed. TCAD simulation reveals lower electrical potential and impact ionization with the proposed structure. Ron-sp/BVD ratio reduction and significant HCl SOA improvement have been verified on real Silicon. Newly layout with Slot-Poly design has been investigated for better process control as well.
Coordinate control of cytoskeletal remodeling and calcium mobilization during T‐cell activation (2013)

Ca(2+) mobilization and cytoskeletal reorganization are key hallmarks of T-cell activation, and their interdependence has long been recognized. Recent advances in the field have elucidated the molecular pathways that underlie these events and have revealed several points of intersection. Ca(2+) signaling can be divided into two phases: initial events leading to release of Ca(2+) from endoplasmic reticulum stores, and a second phase involving STIM 1 (stromal interaction molecule 1) clustering and CRAC (calcium release activated calcium) channel activation. Cytoskeletal dynamics promote both phases. During the first phase, the actin cytoskeleton promotes mechanotransduction and serves as a dynamic scaffold for microcluster assembly. Proteins that drive actin polymerization such as WASp (Wiskott-Aldrich syndrome protein) and HS1 (hematopoietic lineage cell-specific protein 1) promote signaling through PLCγ1 (phospholipase Cγ1) and release of Ca(2+) from endoplasmic reticulum stores. During the second phase, the WAVE (WASP-family verprolin homologous protein) complex and the microtubule cytoskeleton promote STIM 1 clustering at sites of plasma membrane apposition, opening Orai channels. In addition, gross cell shape changes and organelle movements buffer local Ca(2+) levels, leading to sustained Ca(2+) mobilization. Conversely, elevated intracellular Ca(2+) activates cytoskeletal remodeling. This can occur indirectly, via calpain activity, and directly, via Ca(2+) -dependent cytoskeletal regulatory proteins such as myosin II and L-plastin. While it is true that the cytoskeleton regulates Ca(2+) responses and vice versa, interdependence between Ca(2+) and the cytoskeleton also encompasses signaling events that occur in parallel, downstream of shared intermediates. Inositol cleavage by PLCγ1 simultaneously triggers both endoplasmic reticulum store release and diacylglycerol-dependent microtubule organizing center reorientation, while depleting the pool of phosphatidylinositol-4,5-bisphosphate, an activator of multiple actin-regulatory proteins. The close interdependence of Ca(2+) signaling and cytoskeletal dynamics in T cells provides positive feedback mechanisms for T-cell activation and allows for finely tuned responses to extracellular cues.
BER and FER prediction of control and traffic channels for a GSM type of air-interface (2002)

Performance analysis of a mobile communications system is often done separately at network and at link level. It is difficult to study a modern mobile communications system like GSM analytically, due to the complexity. Hence simulations are used. It is desirable to include all link aspects in a network simulator, but without having to simulate every single link, since this would be to time consuming. In this paper a method is presented to find the BER and FER from the signal to interference (C/I) values for a GSM type of air-interface, which can be used for integration of link aspects in a network simulator. The accuracy is within 0.2 dB in case of the BER and 0.5 for the FER. Both traffic and control channels are studied and the method is independent of hopping sequences and speed.
The Fluorination of Chlorodisiloxane. Silicon Oxyfluoride<sup>1</sup> (1945)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Fluorination of Chlorodisiloxane. Silicon Oxyfluoride1Harold Simmons Booth and Reuben Alexander OstenCite this: J. Am. Chem. Soc. 1945, 67, 7, 1092–1096Publication Date (Print):July 1, 1945Publication History Published online1 May 2002Published inissue 1 July 1945https://pubs.acs.org/doi/10.1021/ja01223a021https://doi.org/10.1021/ja01223a021research-articleACS PublicationsRequest reuse permissionsArticle Views224Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Association of PET index quantifying skeletal uptake in NaF PET/CT images with overall survival in prostate cancer patients. (2017)

178 Background: Bone Scan Index (BSI) derived from 2D whole-body bone scans is considered an imaging biomarker of bone metastases burden carrying prognostic information. Sodium fluoride (NaF) PET/CT is more sensitive than bone scan in detecting bone changes due to metastases. We aimed to develop a semi-quantitative PET index similar to the BSI for NaF PET/CT imaging and to study its relationship to BSI and overall survival in patients with prostate cancer. Methods: NaF PET/CT and bone scans were analyzed in 48 patients (aged 53-92 years) with prostate cancer. Thoracic and lumbar spines, sacrum, pelvis, ribs, scapulae, clavicles, and sternum were automatically segmented from the CT images, representing approximately 1/3 of the total skeletal volume. Hotspots in the PET images, within the segmented parts in the CT images, were visually classified and hotspots interpreted as metastases were included in the analysis. The PET index was defined as the quotient obtained as the hotspot volume from the PET images divided by the segmented bone tissue volume from the CT images. BSI was automatically calculated using EXINIbone BSI . Results: The correlation between the PET index and BSI was r 2 = 0.54. The median BSI was 0.39 (IQR 0.08-2.05). The patients with a BSI ≥ 0.39 had a significantly shorter median survival time than patients with a BSI < 0.39 (2.3 years vs. not reached after 5 years). BSI was significantly associated with overall survival (HR 1.13, 95% CI 1.13 to 1.41; p < 0.001), and the C-index was 0.68. The median PET index was 0.53 (IQR 0.02-2.62). The patients with a PET index ≥ 0.53 had a significantly shorter median survival time than patients with a PET index < 0.53 (2.5 years vs. not reached after 5 years). The PET index was significantly associated with overall survival (HR 1.18, 95% CI 1.01 to 1.30; p < 0.001) and C-index was 0.68. Conclusions: PET index based on NaF PET/CT images was correlated to BSI and significantly associated with overall survival in patients with prostate cancer. Further studies are needed to evaluate the clinical value of this novel 3D PET index as a possible future imaging biomarker.
The Morphology and Microstructure of Colloidal Silver and Gold (1987)

Colloid-chemically synthesized gigantic gold and silver clusters and microparticles have been investigated by high-resolution electron microscopy. In the case of the gold samples decahedral and icosahedral, multitwinned and triangular flattened particles were characterized. In the silver samples there were extremely small particles (<40 Å, see right-hand side of picture) whose structure is interpreted in terms of a pentagonal packing of the atoms. The inset shows a structural model (left, top) and a computer-simulated image (left, bottom).
COCA: Online Resource Management for Cost Minimization and Carbon Neutrality in Data Centers (2013)

Due to the enormous energy consumption and associated environmental concerns, data centers have been increasingly pressured to reduce long-term net carbon footprint to zero, i.e., carbon neutrality. In this paper, we propose an online algorithm, called CACO (optimizing for COst minimization and CArbon neutrality), for minimizing data center operational cost while satisfying carbon neutrality without long-term future information. Unlike the existing research, CACO enables distributed server-level resource management: each server autonomously adjusts its processing speed and optimally decides the amount of workloads to process. We prove that CACO achieves a close-to-minimum operational cost (incorporating both electricity and delay costs) compared to the optimal algorithm with future information, while bounding the potential violation of carbon neutrality. We also perform trace-based simulation studies to complement the analysis, and the results show that CACO reduces the cost by more than 25% (compared to the state of the art) while resulting in a smaller carbon footprint.
Silicon monoxide influence on silicon nanocrystal formation (2012)

Study of silicon nanocrystal (Si-nc) formation in SiO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</inf> layers during high temperature annealing was fulfilled by Monte Carlo simulation. Role of silicon monoxide in the process of cluster nucleation and growth was analyzed. Dependencies of Si-nc size, number of clusters on temperature and annealing time for open and closed systems were obtained. Simulation demonstrated that presence of silicon monoxide increased critical nucleus size and could accelerate Si-nc aggregation rate.
E-selectin is present in proliferating endothelial cells in human hemangiomas. (1996)

E-selectin, an endothelial-cell-specific leukocyte adhesion molecule, may also function in angiogenesis. To investigate its role in a noninflammatory angiogenic disease, E-selectin was analyzed by immunohistochemistry in specimens of proliferative phase and involutive phase hemangiomas. Hemangioma is an endothelial cell tumor of capillary blood vessels that grows rapidly during infancy and regresses spontaneously during childhood. E-selectin expression was high in proliferative phase specimens and was co-localized with dividing microvascular endothelial cells. Relative to the number of blood vessels, E-selectin declined significantly in involutive phase specimens demonstrating that E-selectin correlates with angiogenesis in the tumors. E-selectin was not detected in quiescent endothelium but was co-localized in dividing microvascular endothelial cells in placenta and neonatal foreskin, two tissues with ongoing growth of microvessels. These in vivo studies support the hypothesis that E-selectin functions in angiogenesis and suggest that E-selectin may be a marker for proliferating endothelium.
Dietary obesity in nine inbred mouse strains (1992)

The effect of 7 wk consumption of a diet containing 32.6% of kilocalories as fat [condensed milk (CM) diet] on body composition and energy intake was evaluated in nine strains of inbred mice (AKR/J, C57L/J, A/J, C3H/HeJ, DBA/2J, C57BL/6J, SJL/J, I/STN, and SWR/J). Control animals were fed a high-carbohydrate diet containing 11.6% of energy as fat (Purina Rodent Chow diet). Relative to Chow diet controls, the CM diet significantly increased carcass lipid content in six strains (AKR/J, C57L/J, A/J, C3H/HeJ, DBA/2J, and C57BL/6J), but had no or a marginal effect on adiposity in three strains of mice (SJL/J, I/STN, and SWR/J). The obesity produced by the CM diet in six strains was not due to hyperphagia. Only one of six (AKR/J) of the strains that increased adiposity on the CM diet consumed more energy than controls during the 7 wk of the experiment. The identification of inbred mouse strains that are sensitive to dietary obesity, vs. others that are resistant, provides a useful tool to pursue the metabolic and genetic basis of this trait in the mouse.
796. Steric effects in di- and tri-arylmethanes. Part I. Electronic absorption spectra of o-methyl derivatives of Michler's hydrol blue and crystal violet; conformational isomers of crystal violet (1959)

C. C. Barker, M. H. Bridge and A. Stamp, J. Chem. Soc., 1959, 3957 DOI: 10.1039/JR9590003957
A Protocadherin-Cadherin-FLRT3 Complex Controls Cell Adhesion and Morphogenesis (2009)

PAPC and FLRT3 form a functional complex with cadherins and PAPC functions as a molecular "governor" to maintain FLRT3 activity at the optimal level for physiological regulation of C-cadherin adhesion, cell sorting, and morphogenesis.
A Data Correction Algorithm for Low-Frequency Floating Car Data (2018)

The data collected by floating cars is an important source for lane-level map production. Compared with other data sources, this method is a low-cost but challenging way to generate high-accuracy maps. In this paper, we propose a data correction algorithm for low-frequency floating car data. First, we preprocess the trajectory data by an adaptive density optimizing method to remove the noise points with large mistakes. Then, we match the trajectory data with OpenStreetMap (OSM) using an efficient hierarchical map matching algorithm. Lastly, we correct the floating car data by an OSM-based physical attraction model. Experiments are conducted exploiting the data collected by thousands of taxies over one week in Wuhan City, China. The results show that the accuracy of the data is improved and the proposed algorithm is demonstrated to be practical and effective.
The Cardiovascular Tissue‐Reactor: A Novel Device for the Engineering of Heart Valves (2006)

The shortage of human donor valves and disadvantages of current mechanical and xenogenic valve grafts cause a growing demand for biologically engineered valves. We developed a bioreactor for in vitro transformation of porcine semilunar heart valves into human valves. The reactor design was optimized in order to achieve a complete removal of porcine cells by trypsinization and cellularization of the remaining matrix with human vascular cells. The physical parameters of the reactor were characterized. Based on these data, decellularization and cellularization protocols were developed and the successful application of protocols was investigated by immunohistochemistry. The resulting reactor consisted of two connectable and perfuseable modules. Heart valve structures of varying sizes could be mounted into the reactor and could be completely depopulated within 4 days by a sequence of enzymatic and mechanical treatments applied simultaneously to the valves. Complete cellularization with human cells could be achieved after optimizing the seeding design, density, and time.
Epidermal growth factor and platelet-derived growth factor in blood in diabetes mellitus (1990)

Epidermal and platelet-derived growth factors are potent mitogens for many types of cells, including smooth muscle cells. Epidermal growth factor in blood of humans is present both in platelets (as reflected in its serum level) and in plasma, the source(s) of which remains unknown. We assayed its level in 82 diabetic patients and 53 age-matched controls. In diabetes, epidermal growth factor level was increased in serum (191 +/- 43 vs 155 +/- 64 pmol/l, p = 0.0002) and plasma (53 +/- 9 vs 38 +/- 14 pmol/l, p less than 0.0001), without any difference between the patients with and without complications. Platelet-derived growth factor level was assayed only in serum of 19 patients with uncomplicated diabetes and found elevated (222 +/- 47) as compared with 13 controls (160 +/- 26 pmol/l), (p = 0.0002). Type of diabetes, its duration, mode of therapy, control, presence of retinopathy or albuminuria (in case of epidermal growth factor), as well as C-peptide age and sex did not correlate with epidermal or platelet-derived growth factor levels. Serum but not plasma epidermal and platelet-derived growth factor were negatively correlated with serum creatinine (correspondingly, r = -0.373, p = 0.0008 and r = -0.564, p = 0.0285). It is concluded that diabetes itself and not its complications cause increased levels of epidermal growth factor in plasma and serum and of platelet-derived growth factor in serum.
Frequency Multiply Circuit for Superconducting A/D Converter (2005)

A new frequency multiply circuit generating a 20 GHz sampling clock from an external 5 GHz signal for a lowpass sigma-delta modulator was proposed and designed. The multiply circuit was composed of a ladder circuit, a modified Josephson transmission line (JTL) and T-flip flop (T-FF). We confirmed by numerical simulation that the period jitter of SFQ pulse trains generated by the ladder circuit could be reduced to a value small enough to realize 14-bit resolution for 10 MHz bandwidth by utilizing the repulsion effect between SFQ pulses in the modified JTL. The multiply circuit was fabricated by a 2.5 kA/cm/sup 2/ Nb process, and its correct operation was confirmed.
Organocatalytic Highly Enantioselective Mannich-Type Reactions of Fluoromalonate with N-Boc-Aldimines (2010)

The catalytic enantioselective Mannich reaction promoted by chiral bifunctional organocatalysts is described. The treatment of diethyl fluoromalonate with N-Boc-aldimines under mild reaction conditions afforded the corresponding β-amino-β-fluoromalonates with excellent enantioselectivity (93-97% ee).
SAND: Semi-Supervised Adaptive Novel Class Detection and Classification over Data Stream (2016)

Most approaches to classifying data streams either divide the stream into fixed-size chunks or use gradual forgetting. Due to evolving nature of data streams, finding a proper size or choosing a forgetting rate without prior knowledge about time-scale of change is not a trivial task. These approaches hence suffer from a trade-off between performance and sensitivity. Existing dynamic sliding window based approaches address this problem by tracking changes in classifier error rate, but are supervised in nature. We propose an efficient semi-supervised framework in this paper which uses change detection on classifier confidence to detect concept drifts, and to determine chunk boundaries dynamically. It also addresses concept evolution problem by detecting outliers having strong cohesion among themselves. Experiment results on benchmark and synthetic data sets show effectiveness of the proposed approach.
DESIGN OF METALLIC MESH ABSORBERS FOR HIGH BANDWIDTH ELECTROMAGNETIC WAVES (2009)

International audience
Comparison of Plasma Fentanyl Concentrations by Using Three Transdermal Fentanyl Patch Sizes in Dogs (1998)

Because of the interindividual and intraindividual variation in plasma fentanyl concentrations, patches should be applied 24 hours before the anticipated time that analgesia will be required. Adequacy of analgesia and potentially deleterious side effects, such as sedation and respiratory depression, should be monitored while the patches are in place. Skin reactions may occur, and the patches should be removed if such skin irritation is seen. After the patch is removed, it is expected that analgesia will wane rapidly because of the brief elimination half-life.
Effects of Estrogens and Progestins on the Biochemistry and Morphology of the Postmenopausal Endometrium (1981)

To study the effects of exogenous estrogens on the postmenopausal endometrium, and to determine the time course and minimum dosage of added progestins necessary to oppose estrogen stimulation, we obtained endometrial specimens from symptomatic postmenopausal women being treated with various preparations of estrogens and progestins. Morphologic changes were assessed with light and electron microscopy, and biochemical effects through measurement of DNA synthesis, estradiol and progesterone receptors, and isocitric and estradiol dehydrogenase activity. For comparison, identical studies were carried out on specimens from premenopausal women in the proliferative and secretory phases of their cycle. All the estrogens exerted stimulatory effects in the postmenopausal specimens that were comparable to those observed in the premenopausal proliferative-phase specimens. Estropipate, subcutaneous estradiol, and conjugated estrogens had some hyperphysiologic effects. Maximal progestational effects occurred in the postmenopausal specimens only after norethindrone was administered for six days, and a constant level of activity equal to that in premenopausal secretory-phase specimens was then observed until the 10th day of exposure. Similar maximal effects occurred after six days of treatment with D/L-norgestrel (150 and 5 mg daily [10 mg daily produced less complete changes]). We conclude that many estrogen preparations subject the endometrium to a potent stimulus. Norethindrone and norgestrel are protective because they counteract the proliferative effects of estrogens, but the currently recommended daily dosages of these progestins can be greatly reduced without loss of response.