gebhart/patrepeval huggingface dataset:
Cerebral Microvascular Responses to Hypercholesterolemia (2003)

Although hypercholesterolemia is widely accepted as a major risk factor for coronary artery and peripheral vascular diseases, its role in the pathogenesis of stroke is controversial. The objectives of this study were to determine how hypercholesterolemia affects the cerebral microcirculation under resting conditions and after ischemia-reperfusion (I/R). Platelet- and leukocyte-endothelial cell interactions and oxidant production (using the oxidant-sensitive fluorochrome dihydrorhodamine-123) were monitored by intravital videomicroscopy in the cerebral microvasculature of mice placed on either a normal (ND) or cholesterol-enriched diet (HCD). Platelets labeled with carboxyfluorescein diacetate succinimidyl ester (CFDASE) and leukocytes labeled with rhodamine 6G were seen to roll and firmly adhere, with a corresponding increase in oxidant production, in venules of mice on HCD, but not ND. Immunoneutralization of P-selectin attenuated the platelet- and leukocyte-endothelial cell interactions and the enhanced oxidant production associated with HCD. A GPIIb/IIIa blocking antibody did not alter the blood cell-vessel wall interactions to HCD. Mice deficient in the NADPH oxidase subunit gp91(phox) exhibited significantly blunted platelet and leukocyte recruitment responses to HCD. Focal I/R also elicited inflammatory and prothrombogenic responses in cerebral venules and these were exaggerated in mice on HCD. These results implicate an oxidant-dependent, P-selectin-mediated mechanism in the blood cell-vessel wall interactions induced by hypercholesterolemia in the brain and demonstrate that the deleterious effects of I/R on the brain are exacerbated by this cardiovascular risk factor.
Mice Heterozygous for Tumor Necrosis Factor-α Converting Enzyme Are Protected From Obesity-Induced Insulin Resistance and Diabetes (2007)

Our results suggest that modulation of TACE activity is a new pathway to be investigated for development of agents acting against obesity and its metabolic complications.
Synchronization of Neural Activity across Cortical Areas Correlates with Conscious Perception (2007)

Subliminal stimuli can be deeply processed and activate similar brain areas as consciously perceived stimuli. This raises the question which signatures of neural activity critically differentiate conscious from unconscious processing. Transient synchronization of neural activity has been proposed as a neural correlate of conscious perception. Here we test this proposal by comparing the electrophysiological responses related to the processing of visible and invisible words in a delayed matching to sample task. Both perceived and nonperceived words caused a similar increase of local (gamma) oscillations in the EEG, but only perceived words induced a transient long-distance synchronization of gamma oscillations across widely separated regions of the brain. After this transient period of temporal coordination, the electrographic signatures of conscious and unconscious processes continue to diverge. Only words reported as perceived induced (1) enhanced theta oscillations over frontal regions during the maintenance interval, (2) an increase of the P300 component of the event-related potential, and (3) an increase in power and phase synchrony of gamma oscillations before the anticipated presentation of the test word. We propose that the critical process mediating the access to conscious perception is the early transient global increase of phase synchrony of oscillatory activity in the gamma frequency range.
Structure and Properties of a 19Cr-25Ni-Mo-Ti Steel (1979)

SANDVIK 12RN72 is a 19Cr-25Ni austenitic steel with additions of molybdenum, titanium, and boron. In this paper structure, mechanical properties, and high-temperature corrosion properties of 12RN72 are presented. The structure of 12RN72 in the solution heat treated condition consists of a fully austenitic matrix with some undissolved carbides and nitrides of type TiC and TiN. During creep, M23C6 precipitates in the grain boundaries, and both M23C6 and finely dispersed TiC-particles precipitate in the grains. The small TiC-particles, which precipitate at dislocations, are very stable and their growth rate is low. The precipitates of TiC and M23C6 greatly contribute to a high creep-rupture strength. For instance, at 700°C the 100 000 h creep-rupture strength of 12RN72 is at least twice that of TP316 and TP347 and about 50 percent higher than that of Alloy 800H. Another prominent feature is the high creep ductility with a transcrystalline rupture behavior. The high chromium and nickel contents of 12RN72 account for an improved corrosion resistance at elevated temperature in comparison with the standard austenitic steels. Up to about 1000°C, the corrosion properties are similar to those of Alloy 800H that has been verified by tests in air, steam, and impure helium.
Taste and structure in phenolic glycosides (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTaste and structure in phenolic glycosidesRobert M. Horowitz and Bruno GentiliCite this: J. Agric. Food Chem. 1969, 17, 4, 696–700Publication Date (Print):July 1, 1969Publication History Published online1 May 2002Published inissue 1 July 1969https://pubs.acs.org/doi/10.1021/jf60164a049https://doi.org/10.1021/jf60164a049research-articleACS PublicationsRequest reuse permissionsArticle Views622Altmetric-Citations111LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Endotracheal Tube Ignition by Electrocautery During Tracheostomy: Case Report with Autopsy Findings (1991)

This case of upper airway tract fire resulting from the use of electrocautery during elective tracheostomy has significance for surgeons, anesthetists, and forensic pathologists alike. The major autopsy findings are described and illustrated. Suggestions that may help to prevent or minimize the risk of fire in this context are reviewed.
Expression of NeuroD and TrkB in developing and aged mouse olfactory epithelium (2001)

To better understand the roles of NeuroD, a member of the basic helix-loop-helix transcription factor family, during the differentiation of olfactory receptor neurons, we studied the expression of NeuroD in developing and aging mouse olfactory epithelium (OE). During embryonic period, NeuroD expression is confined in the basal compartment of OE. During neonatal period, NeuroD expression is detected in the middle compartment and in the basal compartment of OE. In the adult, the number of NeuroD expressing cells in the basal compartment significantly decreased, while the NeuroD-positive cells in the middle compartment was maintained throughout lifetime. This dual phase expression pattern of NeuroD suggests multiple roles of NeuroD in the neurogenesis of ORNs.
Ce<sup>3+</sup> and Ln<sup>3+</sup> (Ln = Dy, Eu, Sm, Tb) Codoped SrF<sub>2</sub> Nanoparticles: Synthesis and Multicolor Light Emission (2016)

For optically active Ln3+ ions, fluoride is a very good luminescent substrate that has been used in the field of lasers, solid-phase optical transmitters, optical communications, up/down conversion. This work reports a systematic study on bridging between structure and tunable luminescence for SrF2:Ce3+/Ln3+ (Ln = Dy, Eu, Sm, Tb) nanoparticles. Regardless of the dopant level, all nano-crystals crystallized in a single cubic phase with the diameter of ~20-30 nm. It was found that SrF2:Ce3+ exhibited intense ultraviolet emission under 288 nm excitation which can be attributed to the typical 4f-5d transition of Ce3+ ions. After the incorporation of Ln3+ ions, multicolor emission can be achieved when excited by the 4f-5d transition of Ce3+. This result gave an evidence that the excitation energy of Ce3+ can be transferred to Ln3+ leading to multicolor emission. The findings reported in this work may provide useful information in designing novel luminescent materials for tailored performances.
<i>Research Notes</i>Sequence and Expression of a Wheat Gene that Encodes a Novel Protein Associated with Pathogen Defense (1992)

Wheat (Triticum aestivum) exhibits local acquired resistance to the powdery mildew pathogen Erysiphe graminis f. sp. tritici. The resistant state can be induced by a preinoculation with the nonhost pathogen E. g.f. sp. hordei, the barley powdery mildew, and is accompanied by the activation of putative defense genes. Here, we report the sequence of a pathogen-induced gene, WIR1a, and a corresponding cDNA, WIR1, that encode novel defense-related proteins of 88 and 85 amino acids, respectively. Analysis of the primary structure of these proteins predicts them to be integral membrane proteins with extracytoplasmic C-terminal domains rich in proline and glycine, through which the proteins possibly interact with the cell wall.
Polyalloöcimene<sup>1</sup> (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPolyalloöcimene1C. S. Marvel, P. E. Kiener, and E. D. VesselCite this: J. Am. Chem. Soc. 1959, 81, 17, 4694–4697Publication Date (Print):September 1, 1959Publication History Published online1 May 2002Published inissue 1 September 1959https://pubs.acs.org/doi/10.1021/ja01526a062https://doi.org/10.1021/ja01526a062research-articleACS PublicationsRequest reuse permissionsArticle Views87Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
UPS systems: a review (2003)

Available uninterruptible power supplies (UPS) are reviewed and some of the design criterion in their development is discussed. A 300 V DC output UPS is covered in detail. Its application to large systems such as mainframes is considered, and it is recommended that if connection problems can be overcome then UPS should be considered for PC power supply.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Laminar heat transfer to spherically blunted cones at hypersonic conditions (1964)

1 Forstall, W, Jr and Shapiro, H, Momentum and mass transfer in coaxial gas jets, J Appl Mech 10, 399-408 (December 1950) 2 Pai, S I , Fluid Dynamics of Jets (D Van Nostrand Co , Inc , Princeton, N J , 1954), Chaps 5-7, pp 96-173 3 Willis, D R and Glassman, I , The mixing of unbounded coaxial compressible streams/ Jet Propulsion 27, 1241-1248 (1957) 4 Pitkin, E T and Glassman, I , Experimental mixing profiles of a Mach 2 6 free jet, J Aerospace Sci 25, 791-792 (1958) 5 Grey, J , Jacobs, P F , and Sherman, M P , Calorimetric probe for the measurement of extremely high temperatures, ' Rev Sci Instr 33, 738-741 (July 1962) 6 Grey, J , Thermodynamic methods of high temperature measurement, Am Soc Mech Engrs Annual Meeting, Philadelphia, Pa (November 18, 1963); also Instr Soc Am (submitted for publication) 7 Sherman, M P , Jacobs, P F , and Grey, J , Analytical and experimental study of radiation from an argon arc jet, Princeton Univ Aeronaut Eng Rept 658 (July 1963) 8 Grey, J , Sherman, M P , and Jacobs, P F , A collimated total radiation probe for arcjet measurements,' Inst Elec Electron Engrs Intern Symp Plasma Phenomena and Measurements, San Diego, Calif (October 31, 1963); also Inst Elec Electron Engrs Trans Nucl Sci (January 1964) 9 Grey, J and Jacobs, P F , ' Turbulent mixing in a partially ionized gas, Princeton Univ Aeronaut Eng Rept 625 (September 1962) 10 Sherman, M P and Grey, J , The degree of approach to equilibrium in an atmospheric-pressure arcjet using argon, ' Princeton Univ Aeronaut Eng Rept 645 (April 1963) 11 Cann, G L and Ducati, C , mollier chart, ' Air Force Office Sci Res AF 49(638)-54 (February 1959) 12 Bosnjakovic, R , Springe, W, Knoche, K F , and Burghoi te, P , Mollier Enthalpie—Entropie Diagramm fur Argon Plasma im Gleichgewicht, ' transl by J F Gross, Warmetechnische Institut, Technische Hochschule, Braunschweig (August 1958) 13 Squire, H B and Trouncer, J, Round jets in a general stream, ' Brit Aeronaut Res Comm Repts and Memo 1974, pp 9-31 (January 1944) 14 Corrsin, S and Uberoi, M S , Further experiments on the flow and heat transfer in a heated turbulent air jet, NACA Rept 998(1950)
The LDL to HDL Cholesterol Ratio as a Valuable Tool to Evaluate Coronary Heart Disease Risk (2008)

The current National Cholesterol Education Program Adult Treatment Panel III guidelines recommend specific target levels of LDL cholesterol (LDL-C) and HDL cholesterol (HDL-C) for determining cardiovascular disease (CVD) risk and evaluating the effectiveness of lipid-lowering therapies. While there is a growing consensus that levels of apolipoprotein (apo) B and the ratio of apo B/apo A-I are more accurate predictors of CVD risk, the question has been raised as to whether it is realistic to expect patients and health professionals to switch from cholesterol-based guidelines to apolipoprotein-based guidelines. Because it will take time before apolipoprotein terminology is recognized by the general public and recommended by the NCEP Adult Treatment panel to evaluate risk, it may be more efficacious to continue adhering to the already familiar and proven measurements of the LDL-C/HDL-C ratio. The following review provides evidence that the LDL-C/HDL-C ratio continues to be a valuable and standard tool to evaluate CVD risk in all populations.
The development and evaluation of a computer-based program to test and to teach the recognition of facial affect (2002)

Autism is a chronic pervasive neurodevelopmental disorder characterized by the early onset of social and communicative impairments as well as restricted, ritualized, stereotypic behavior. The endophenotype of autism includes neuropsychological deficits, for instance a lack of "Theory of Mind" and problems recognizing facial affect. In this study, we report the development and evaluation of a computer-based program to teach and test the ability to identify basic facially expressed emotions. 10 adolescent or adult subjects with high-functioning autism or Asperger-syndrome were included in the investigation. A priori the facial affect recognition test had shown good psychometric properties in a normative sample (internal consistency: rtt=.91-.95; retest reliability: rtt=.89-.92). In a prepost design, one half of the sample was randomly assigned to receive computer treatment while the other half of the sample served as control group. The training was conducted for five weeks, consisting of two hours training a week. The trained individuals improved significantly on the affect recognition task, but not on any other measure. Results support the usefulness of the program to teach the detection of facial affect. However, the improvement found is limited to a circumscribed area of social-communicative function and generalization is not ensured.
Branched Alkyl Alcohol Propoxylated Sulfate Surfactants for Improved Oil Recovery (2010)

Abstract This investigation considers branched alkyl alcohol propoxylated sulfate surfactants as candidates for chemcial enhanced oil recovery (EOR) applications. Results show that these anionic surfactants may be preferred candidates for EOR as they can be effective at creating low interfacial tension (IFT) at dilute concentrations, without requiring an alkaline agent or cosurfactant. In addition, some of the formulations exhibit a low IFT at high salinity, and hence may be suitable for use in more saline reservoirs. Adsorption tests onto kaolinite clay indicate that the loss of these surfactants can be comparable to or greater than other types of anionic surfactants. Surfactant performance was evaluated in oil recovery core flood tests. Selected formulations recovered 35–50% waterflood residual oil even with dilute 0.2 wt% surfactant concentrations from Berea sandstone cores.
Sp100A promotes chromatin decondensation at a cytomegalovirus-promoter–regulated transcription site (2013)

Promyelocytic leukemia nuclear bodies (PML-NBs)/nuclear domain 10s (ND10s) are nuclear structures that contain many transcriptional and chromatin regulatory factors. One of these, Sp100, is expressed from a single-copy gene and spliced into four isoforms (A, B, C, and HMG), which differentially regulate transcription. Here we evaluate Sp100 function in single cells using an inducible cytomegalovirus-promoter–regulated transgene, visualized as a chromatinized transcription site. Sp100A is the isoform most strongly recruited to the transgene array, and it significantly increases chromatin decondensation. However, Sp100A cannot overcome Daxx- and α-thalassemia mental retardation, X-linked (ATRX)–mediated transcriptional repression, which indicates that PML-NB/ND10 factors function within a regulatory hierarchy. Sp100A increases and Sp100B, which contains a SAND domain, decreases acetyl-lysine regulatory factor levels at activated sites, suggesting that Sp100 isoforms differentially regulate transcription by modulating lysine acetylation. In contrast to Daxx, ATRX, and PML, Sp100 is recruited to activated arrays in cells expressing the herpes simplex virus type 1 E3 ubiquitin ligase, ICP0, which degrades all Sp100 isoforms except unsumoylated Sp100A. The recruitment Sp100A(K297R), which cannot be sumoylated, further suggests that sumoylation plays an important role in regulating Sp100 isoform levels at transcription sites. This study provides insight into the ways in which viruses may modulate Sp100 to promote their replication cycles.
The effects of fruit juices and fruits on the absorption of iron from a rice meal (1987)

The effects of the chemical composition of fruit juices and fruit on the absorption of iron from a rice (Oryza sativa) meal were measured in 234 parous Indian women, using the erythrocyte utilization of radioactive Fe method. The corrected geometric mean Fe absorptions with different juices varied between 0.040 and 0.129, with the variation correlating closely with the ascorbic acid contents of the juices (rs 0.838, P less than 0.01). Ascorbic acid was not the only organic acid responsible for the promoting effects of citrus fruit juices on Fe absorption. Fe absorption from laboratory 'orange juice' (100 ml water, 33 mg ascorbic acid and 750 mg citric acid) was significantly better than that from 100 ml water and 33 mg ascorbic acid alone (0.097 and 0.059 respectively), while Fe absorption from 100 ml orange juice (28 mg ascorbic acid) was better than that from 100 ml water containing the same amount of ascorbic acid (0.139 and 0.098 respectively). Finally, Fe absorption from laboratory 'lemon juice' (100 ml orange juice and 4 g citric acid) was significantly better than that from 100 ml orange juice (0.226 and 0.166 respectively). The corrected geometric mean Fe absorption from the rice meal was 0.025. Several fruits had little or no effect on Fe absorption from the meal (0.013-0.024). These included grape (Vitis vinifera), peach (Prunus persica), apple (Malus sylvestris) and avocado pear (Persea americana). Fruit with a mild to moderate enhancing effect on Fe absorption (0.031-0.088) included strawberry (Fragaria sp.) (uncorrected values), plum (Prunus domestica), rhubarb (Rheum rhaponticum), banana (Musa cavendishii), mango (Mangifera indica), pear (Pyrus communis), cantaloup (Cucumis melo) and pineapple (Ananas comosus) (uncorrected values). Guava (Psidium guajava) and pawpaw (Carica papaya) markedly increased Fe absorption (0.126-0.293). There was a close correlation between Fe absorption and the ascorbic acid content of the fruits tested (rs 0.738, P less than 0.0001). There was also a weaker but significant correlation with the citric acid content (rs 0.55, P less than 0.03). Although this may have reflected a direct effect of citric acid on Fe absorption, it should be noted that fruits containing citric acid also contained ascorbic acid (rs 0.70, P less than 0.002).(ABSTRACT TRUNCATED AT 400 WORDS)
Fully-Automatic Branch Labelling of Voxel Vessel Structures (2001)

Today, it is possible to acquire volume representations of the vessel structures in the brain. The selfadjusting probe, a new tool introduced in a previous paper, enables semi-automatic shape extraction.
LEGO-Fi: Transmitter-Transparent CTC with Cross-Demapping (2019)

Cross-Technology Communication (CTC) is an emerging technique that enables direct communication across different wireless technologies. The state-of-the-art works in this area propose physical-level CTC, in which the transmitters emulate signals that follow the receiver's standard. Physical-level CTC means considerable processing complexity at the transmitter, which doesn't apply to the communication from a low-end transmitter to a high-end receiver, e.g. from ZigBee to WiFi. This paper presents transmitter-transparent cross-technology communication, which leaves the processing complexity solely at the receiver side and therefore makes a critical advance toward bidirectional high-throughput CTC. We implement our proposal as LEGO-Fi, the communication from ZigBee to WiFi. The key technique inside is cross-demapping, which stems from two key technical insights: (1) A ZigBee packet leaves distinguishable features when passing the WiFi modules. (2) Compared to ZigBee's simple encoding and modulation schemes, the rich processing capacity of WiFi offers extra flexibility to process a ZigBee packet. The evaluation results show that LEGO-Fi achieves a throughput of 213.6Kbps, which is respectively 13000× and 1200× faster than FreeBee and ZigFi, the two existing ZigBee-to-WiFi CTC approaches.
Imposing tight specifications on analog IC's through simultaneous placement and module optimization (2002)

Techniques are presented for simultaneous placement and module optimization for analog ICs. An algorithmic approach to module generation provides alternative sets of modules, optimized with respect to performance but with different trade-offs among area, parasitics and matching. A simulated annealing algorithm performs the placement, selecting among the available configurations the one that best fulfils all performance and geometric requirements. Compared to standard approaches, the flexibility of placement is considerably increased, thus allowing the enforcement of tighter specifications.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>