gebhart/patrepeval huggingface dataset:
New Oxypyridinate Paddlewheel Ligands for Alkane-Soluble, Sterically-Protected Ru<sub>2</sub>(II,III) and Ru<sub>2</sub>(II,II) Complexes (2018)

The paddlewheel complex Ru<sub>2</sub>(chp)<sub>4</sub>Cl (1-Cl, chp = 6-chloro-2-oxypyridinate), upon reduction with Zn, has been previously shown to dimerize to [Ru<sub>2</sub>(chp)<sub>4</sub>]<sub>2</sub> (2), blocking further chemistry at the Ru<sub>2</sub>(II,II) axial site [ Inorg. Chem. 2015 , 54 , 8571 - 8589 ]. Functionalization of the chp ligand at the 3 and 5 positions with either bromine (dbchpH = 3,5-dibromo-6-chloro-2-pyridone) or trimethylsilyl (TMS) groups (dsichpH = 6-chloro-3,5-bis(trimethylsilyl)-2-pyridone) allows for the preparation of the Ru<sub>2</sub>(II,II) paddlewheel complexes Ru<sub>2</sub>(dbchp)<sub>4</sub> (3) and Ru<sub>2</sub>(dsichp)<sub>4</sub> (6), respectively, neither of which shows evidence of dimerization. Though the utilization of 3 is limited due to insolubility, complex 6 is soluble even in typically non-coordinating solvents, forming a stable κ<sup>1</sup>-axial adduct in CH<sub>2</sub>Cl<sub>2</sub> (6-CH<sub>2</sub>Cl<sub>2</sub>) and showing evidence of an axial interaction with n-decane. The first example of an axially free Ru<sub>2</sub>(II,II) complex with a <sup>3</sup>A ground state is observed upon crystallization of 6 from benzene (6-C<sub>6</sub>D<sub>6</sub>). Complex 6 is accessed via Zn reduction of Ru<sub>2</sub>(dsichp)<sub>4</sub>Cl (4-Cl), which along with Ru<sub>2</sub>(dsichp)<sub>4</sub>N<sub>3</sub> (4-N<sub>3</sub>), show similar structural and electronic properties to their non-TMS-substituted analogues, 1-Cl and 1-N<sub>3</sub>. Photolysis of 4-N<sub>3</sub> in frozen solution generates Ru<sub>2</sub>(dsichp)<sub>4</sub>N (5); no N atom transfer to PPh<sub>3</sub> is observed upon room temperature photolysis in fluid solution.
INTRASPECIFIC PHYLOGEOGRAPHY: The Mitochondrial DNA Bridge Between Population Genetics and Systematics (1987)

Species distribution models (SDMs) are numerical tools that combine observations of species occurrence or abundance with environmental estimates. They are used to gain ecological and evolutionary insights and to predict distributions across landscapes, ...Read More
Polymyxin B-Induced Release of Low-Molecular-Weight, Heat-Labile Enterotoxin from <i>Escherichia coli</i> (1974)

Polymyxin B-induced release of enterotoxin from Escherichia coli strain H-10407 was demonstrated. Incubation of E. coli cells derived from 6-h cultures with polymyxin caused the rapid release of enterotoxin with a molecular weight of approximately 20,000, as estimated by the gel filtration technique. The rapidity of the release of enterotoxin indicates that it probably resides in the periplasmic space of the cell. The low-molecular-weight enterotoxin possessed vascular permeability factor and diarrheagenic activities, both of which were found to be heat-labile. The permeability factor activity of this enterotoxin was neutralized by antisera prepared against crude E. coli enterotoxin, Vibrio cholerae enterotoxin (choleragen), and V. cholerae toxoid (choleragenoid), respectively. Supernatant fluids of 6-h E. coli cultures did not contain this molecular form of enterotoxin but did contain very high-molecular-weight, heat-labile enterotoxin. Incubation of cells derived from older (18 h) cultures with polymyxin caused the release of both low- (20,000) and high-molecular-weight forms of enterotoxin. We concluded that either the 20,000-dalton form of heat-labile enterotoxin is not released by E. coli under in vitro growth conditions or that enterotoxin released in this form is rapidly destroyed or inactivated.
Molecular cloning and characterization of form I antigen genes of Shigella sonnei (1991)

Sau3AI-generated DNA fragments of the Shigella sonnei large plasmid encoding the form I antigen were cloned into Escherichia coli with cosmid vector pHSG262. One resulting plasmid, designated pJK1137, was studied further. Restriction endonuclease mapping and analysis of transposon Tn3 insertion mutants demonstrated that the form I antigen genes were located within a region of about 12.6 kb consisting of the two contiguous HindIII fragments of 1.26 kb and 12.4 kb. The results of complementation studies between Tn3 insertion mutants of pJK1137 and recombinant plasmids carrying different parts of the form I antigen genes indicated that the 12.6 kb DNA sequence contained at least four gene clusters, regions A, B, C and D. Analysis of radioactively labelled proteins in minicells demonstrated that the DNA sequence of about 12.6 kb coded for at least four specific proteins of 42, 23, 48 and 39 kDa. The former two were coded by region A, the latter two by region D.
Receiver Design for Molecular Communication (2013)

In the Molecular Communication (MC), molecules are utilized to encode, transmit, and receive information. Transmission of the information is achieved by means of diffusion of molecules and the information is recovered based on the molecule concentration variations at the receiver location. The MC is very prone to intersymbol interference (ISI) due to residual molecules emitted previously. Furthermore, the stochastic nature of the molecule movements adds noise to the MC. For the first time, we propose four methods for a receiver in the MC to recover the transmitted information distorted by both ISI and noise. We introduce sequence detection methods based on maximum a posteriori (MAP) and maximum likelihood (ML) criterions, a linear equalizer based on minimum mean-square error (MMSE) criterion, and a decision-feedback equalizer (DFE) which is a nonlinear equalizer. We present a channel estimator to estimate time varying MC channel at the receiver. The performances of the proposed methods based on bit error rates are evaluated. The sequence detection methods reveal the best performance at the expense of computational complexity. However, the MMSE equalizer has the lowest performance with the lowest computational complexity. The results show that using these methods significantly increases the information transmission rate in the MC.
The Entitlement of Chimpanzees to the Common Law Writs of Habeas Corpus and de Homine Replegiando (2007)

In this Article, I claim that humans enslave chimpanzees and thereby deprive them of their bodily liberty and that chimpanzees should be entitled to use the common law writs of habeas corpus and de homine replegiando and to bring their common law claims to bodily liberty before courts. In Part I, I demonstrate that chimpanzees are genetically highly similar to humans and quite cognitively and socially complex. In Part II, I argue that flexibility is part of the common law's basic structure, that legal personhood is one of the common law's basic values, that the structure of the common law requires it to permit such a cause of action to go forward on its merits, and that the claim of chimpanzees to common law legal personhood should always be subject to common law re-evaluation. In Part III, I show that post-Conquest English villeins used writs that allowed them, under certain circumstances, to be declared free. In Part IV, I trace the history of the common law writ of de homine replegiando in England and America and argue that individual chimpanzees are entitled to use it to bring their claims to bodily liberty before common law courts. In Part V, I set out the history of the common law writ of habeas corpus in England and America and argue that individual chimpanzees are entitled to use that common law writ to bring their claims to bodily liberty before common law courts.
Selecting representative IP addresses for internet topology studies (2010)

An Internet hitlist is a set of addresses that cover and can represent the the Internet as a whole. Hitlists have long been used in studies of Internet topology, reachability, and performance, serving as the destinations of traceroute or performance probes. Most early topology studies used manually generated lists of prominent addresses, but evolution and growth of the Internet make human maintenance untenable. Random selection scales to today's address space, but most random addresses fail to respond. In this paper we present what we believe is the first automatic generation of hitlists informed censuses of Internet addresses. We formalize the desirable characteristics of a hitlist: responsiveness, each representative responds to pings; completeness, they cover all the allocated IPv4 address space; and stability, list evolution is minimized when possible. We quantify the accuracy of our automatic hitlists, showing that only one-third of the Internet allows informed selection of representatives. Of informed representatives, 50--60% are likely to respond three months later, and we show that causes for non-responses are likely due to dynamic addressing (so no stable representative exists) or firewalls. In spite of these limitations, we show that the use of informed hitlists can add 1.7 million edge links (a 5% growth) to traceroute-based Internet topology studies Our hitlists are available free-of-charge and are in use by several other research projects.
Apocynin-induced vasodilation involves Rho kinase inhibition but not NADPH oxidase inhibition (2008)

Apocynin per se does not inhibit vascular NADPH-oxidase-dependent superoxide formation. Its in vitro vasodilator actions are not due to NADPH oxidase inhibition but may be explained at least in part by inhibition of Rho kinase activity. The discrepancy between apocynin-induced vasodilation in vitro and the failure of apocynin to lower arterial pressure in SHR suggests opposing effects on arterial pressure-regulating systems in vivo. Its use as a pharmacological tool to investigate vascular NADPH oxidase should be discontinued.
Plastic microring lasers on fibers and wires (1998)

Photopumped, pulsed, narrow line laser emission is demonstrated using cylindrical microcavities formed by π-conjugated polymer thin films wrapped around thin glass optical fibers and metal wires with various diameters D. A variety of cavity-dependent resonant laser mode structures were observed, which for D&lt;10 μm contain a single resonant spectral line of less than 1 Å in width. The microring lasers are also characterized by a well-defined, very low threshold excitation intensity, at which beam directionality and polarization degree dramatically increase. These findings open up the fields of lasers and fiber optics to organic materials.
Synthesis and biological evaluation of some novel quinazolones (2007)

In view of the potent antimicrobial and antiinflammatory activities exhibited by quinazolin-4-(3H)-ones, a series of novel 2, 3-disubstituted-3,1-quinazolin-4-(3H) ones have been synthesized. The synthesized compounds were screened for antibacterial and antiinflammatory activities. Compounds 3a and 3l showed significant antiinflammatory activity comparable to ibuprofen, while the compound 3J showed antibacterial activity comparable to ciprofloxacin.
Hypertrophic Neuropathies and Malignant Peripheral Nerve Sheath Tumors in Transgenic Mice Overexpressing Glial Growth Factor β3 in Myelinating Schwann Cells (2003)

The neuregulin-1 (NRG-1) family of growth and differentiation factors exerts a variety of effects on Schwann cells and their precursors during nervous system development; however, NRG-1 effects on adult Schwann cells are poorly defined. Several lines of evidence suggest that NRG-1 actions on adult Schwann cells are distinct from those observed during development. To test this hypothesis, we generated transgenic mice overexpressing the NRG-1 isoform glial growth factor β3 (GGFβ3) in myelinating Schwann cells [protein zero (P 0 )GGFβ3 mice]. P 0 -GGFβ3 mice develop resting tremors, gait abnormalities, decreased hindlimb strength, and paralysis by ∼7 months of age. Sciatic nerves from these animals show a hypertrophic neuropathy characterized by demyelination, remyelination, and “onion bulb” formation. Development of this hypertrophic neuropathy is preceded by Schwann cell hyperplasia that is prominent in 1-month-old mice and present but decreased in 2- and 4-month-old animals. P 0 -GGFβ3 mice also develop peripheral ganglion-associated malignant peripheral nerve sheath tumors. Motor, sensory, and sympathetic ganglia from 1-, 2-, and 4-month-old P 0 -GGFβ3 mice uniformly contain intraganglionic, likely preneoplastic, Schwann cell proliferations. Examination of bromodeoxyuridine incorporation and caspase-3 activation in sciatic nerves and trigeminal ganglia indicates that Schwann cell hyperplasia in P 0 -GGFβ3 mice reflects increased proliferation rather than decreased apoptosis. These observations are consistent with the hypothesis that GGFβ3 induces proliferation of adult Schwann cells and demyelination of peripheral nerve axons. Furthermore, overexpression of this NRG-1 isoform frequently induces neoplastic Schwann cell proliferation within PNS ganglia, suggesting that NRG-1 may contribute to human Schwann cell neoplasia.
Essential role of ryanodine receptor 2 phosphorylation in the effect of azumolene on ventricular arrhythmia vulnerability in a rabbit heart model (2018)

Ventricular refibrillation following LDVF was reduced by azumolene, which also improves calcium dynamics. RyR2 phosphorylation at Ser2808 is a prerequisite for the beneficial effects of azumolene.
Silicone Foam Additive Manufacturing by Liquid Rope Coiling (2017)

This study investigates the additive manufacturing (AM) of a porous silicone foam by liquid rope coiling, a method in which a thin viscous fluid stream generates a helical coil structure while extruding from a specific height onto a moving surface. The moisture-cured silicone liquid rope coiling experiments were conducted to identify effects of four parameters, height, flow rate, nozzle size, and travelling speed, on the regime diagram and dimensions of coiling patterns, including steady, meandering, figure-of-eight, coiling, and side kicks. The coiling pattern was demonstrated to be feasible for layer-by-layer AM of silicone foams.
Experience with the Water Bed in a Large City Hospital (1968)

These authors faced the grim realization that their patients would continue to develop pressure sores simply because there were not enough people to make sure patients were turned and positioned often enough. They tried the water mattress as one solution. Before you disagree with their reasoning you should have had experience being the only nurse available to cover a 100-bed medical unit on evenings.
Nitric oxide induces apoptosis in the human corpus luteum in vitro (2000)

The present study aimed to investigate the role of nitric oxide (NO) in regression of the human corpus luteum. We therefore examined the effect of both NO and human chorionic gonadotrophin (HCG) on luteal cell apoptosis, and Bcl-2 production. The effect of NO on oestrogen production during corpus luteum regression was also studied. Slices from corpus luteum collected throughout the luteal phase were incubated for 4 h with the nitric oxide synthase (NOS) substrate, L-arginine (L-Arg, 1 mmol/l), the NOS inhibitor N-monomethyl-L-arginine (L-NMMA) (1 mmol/l), or with HCG (10 IU/ml). Oestradiol concentrations were determined by radioimmunoassay; Bcl-2 concentrations were measured by enzyme-linked immunosorbent assay; apoptosis was detected in-situ by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labelling; and inducible nitric oxide synthase (iNOS) was assessed by immunohistochemistry. Consistent with our previous findings, L-Arg elicited an inhibitory action on the production of oestradiol (P< 0.05). The number of apoptotic cells increased (P<0.05) from early to late corpus luteum, as did the number of cells positive for the expression of iNOS. The percentage of apoptotic cells in mid and late luteal phase was increased by L-Arg (56% and 310% respectively; P <0.05), and decreased by L-NMMA and HCG. Although no changes were observed in Bcl-2 concentration during the corpus luteum life span, L-Arg inhibited, and HCG augmented, Bcl-2 production (P<0.05) from mid and late corpus luteum cells in vitro. In summary, these results suggest that the opposite actions of L-Arg and HCG on human corpus luteum viability may, in part, be mediated by changes in the level of the anti-apoptotic activities caused by oestradiol and Bcl-2 protein.
Identification of Pigments in Paint Products by Infrared Spectroscopy (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIdentification of Pigments in Paint Products by Infrared SpectroscopyT. R. Harkins, J. T. Harris, and O. D. ShreveCite this: Anal. Chem. 1959, 31, 4, 541–545Publication Date (Print):April 1, 1959Publication History Published online1 May 2002Published inissue 1 April 1959https://pubs.acs.org/doi/10.1021/ac50164a025https://doi.org/10.1021/ac50164a025research-articleACS PublicationsRequest reuse permissionsArticle Views624Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Early House-Warming by Coal-Fires (1950)

Research Article| December 01 1950 Early House-Warming by Coal-Fires Charles E. Peterson Charles E. Peterson Search for other works by this author on: This Site PubMed Google Scholar Journal of the Society of Architectural Historians (1950) 9 (4): 21–24. https://doi.org/10.2307/987472 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Charles E. Peterson; Early House-Warming by Coal-Fires. Journal of the Society of Architectural Historians 1 December 1950; 9 (4): 21–24. doi: https://doi.org/10.2307/987472 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentJournal of the Society of Architectural Historians Search This content is only available via PDF. Article PDF first page preview Close Modal You do not currently have access to this content.
Adjuvants for malaria vaccines (2009)

Summary There is a renewed enthusiasm about subunit vaccines for malaria coincident with the formation of new alliances and partnerships raising international public awareness, attracting increased resources and the re‐focusing of research programs on adjuvant development for infectious disease vaccines. It is generally accepted that subunit vaccines for malaria will require adjuvants to induce protective immune responses, and availability of suitable adjuvants has in the past been a barrier to the development of malaria vaccines. Several novel adjuvants are now in licensed products or in late stage clinical development, while several others are in the earlier development pipeline. Successful vaccine development requires knowing which adjuvants to use and knowing how to formulate adjuvants and antigens to achieve stable, safe, and immunogenic vaccines. For the majority of vaccine researchers this information is not readily available, nor is access to well‐characterized adjuvants. In this minireview, we outline the current state of adjuvant research and development as it pertains to effective malaria vaccines.
Distortion Exponents for Different Source-Channel Diversity Achieving Schemes over Multi-Hop Channels (2007)

The performance limits of multimedia systems combining source (multiple description) coding and channel coding with user cooperation diversity over multi-hop channels is studied. Performance is measured through the distortion exponent, which measures the rate of decay of the end-to-end distortion at asymptotic high SNRs. Two implementations for user cooperation are considered: amplify-and-forward and decode-and-forward. Results comparing different source and channel coding schemes show that optimum channel coding diversity provides the best performance, followed by source coding diversity. The results also show that at low bandwidth expansion factor, source encoding distortion is the main limiting factor. As the bandwidth expansion factor increases, user cooperation diversity is the main limiting factor, thus, the distortion exponent could be improved by increasing the number of relays.
Procoagulant activity and phosphatidylserine of amniotic fluid cells (2009)

Amniotic fluid (AF) may induce disseminated intravascular coagulation (DIC) when it enters maternal circulation by breaching the placental-maternal circulation barrier. The precise mechanism of the procoagulant activity of AF is unclear, but tissue factor (TF) has been proposed to be the main cause. As one constituent of AF, AF cells accumulate and undergo apoptosis continuously. Therefore, we speculate that AF cells have procoagulant activity due to the externalisation of phosphatidylserine (PS). The present study aims to demonstrate that, in addition to TF, the PS that is externalised on AF cells is important for the procoagulant activity of AF. Ten AF samples from parturient women were analysed using lactadherin as the probe for PS. Anti-TF antibody also was used to identify TF and its associated coagulation functions in AF cells. Normal platelets, neutrophils, and lymphocytes were harvested as controls. Confocal microscopy and flow cytometry was used to assess PS expression on AF cells. The procoagulant activity of AF cells was demonstrated by a plasma coagulation assay and further confirmed by factor Xase/prothrombinase assays. PS and TF were present on most AF cells, providing substantial procoagulant activity. Furthermore, factor Xase and prothrombinase assays showed that AF cells substantially enforced the activation of factor X and prothrombin. PS on AF cells is an important procoagulant source for AF. Lactadherin is an ideal anticoagulant for inhibiting the procoagulant activity of AF cells.
Stabilization of the frequency of a pulse-periodic TEA CO<sub>2</sub>laser by injection of a signal from a low-pressure cw laser (1979)

An investigation was made of the feasibility of stabilizing the frequency of radiation from a TEA CO2 laser due to various vibrational-rotational transitions by injecting radiation from a low-pressure cw CO2 laser. The experimental results show good agreement with the theoretical calculations.