gebhart/patrepeval huggingface dataset:
Carbonates, Thiocarbonates, and the Corresponding Monoalkyl Derivatives. 1. Their Preparation and Isotropic <sup>13</sup>C NMR Chemical Shifts (2001)

Three series of potassium carbonate and thiocarbonate salts were synthesized, and the corresponding (13)C isotropic solid-state NMR and the aqueous solution (13)C and (1)H NMR data were collected. The series of compounds that were studied consists of (1) the parent compounds, i.e., potassium carbonate, K(2)CO(3), potassium hydrogen carbonate, KHCO(3), potassium monothiocarbonate, K(2)CO(2)S, potassium dithiocarbonate, K(2)COS(2), and potassium trithiocarbonate, K(2)CS(3), (2) the oxygen monoalkyl substituted derivatives of the parent compounds (OR series), i.e., three potassium O-alkylcarbonates, KO(2)COR, three potassium O-alkylmonothiocarbonates, KOSCOR, and three potassium O-alkyldithiocarbonates, KS(2)COR, all with R = CH(3), CH(2)CH(3), CH(CH(3))(2), and (3) the sulfur monoalkyl substituted derivatives of the parent compounds (SR series), i.e., two potassium S-alkylmonothiocarbonates, KO(2)CSR; two potassium S-alkyldithiocarbonates, KOSCSR, and two potassium S-alkyltrithiocarbonates, KS(2)CSR, all with R = CH(3) or CH(2)CH(3). The preparation and proper characterization of KO(2)CSR and KOSCSR with R = CH(3) and CH(2)CH(3) along with new IR and X-ray powder diffraction data for several other compounds in the series are reported for the first time in this study. Solution NMR data for KO(2)CSR (R = CH(3), CH(2)CH(3)) and KOSCSR (R = CH(3)) and solid-state NMR data for K(2)CO(2)S and K(2)COS(2) could not be obtained because they are unstable under the corresponding measurement conditions. The isotropic chemical shift values of the central carbon atoms obtained from solid-state MAS (magic angle spinning) NMR experiments deviate at most by 3 ppm from the corresponding solution values. Two major trends in the (13)C chemical shift values of the central carbon atoms were found. First, if an oxygen atom in a parent compound or in an alkyl-substituted derivative is replaced by a sulfur atom, a significantly higher chemical shift value is observed. This trend is discussed in terms of the paramagnetic contribution to the chemical shielding constant. Second, the size of the alkyl group in the monoalkyl derivatives has a very small effect on the chemical shift values of the central carbon atoms. This observation is explained using the concept of varying inductive effects produced by alkyl groups. The trends observed for the (13)C and (1)H chemical shift values of the alkyl groups follow common concepts on the structure dependency of chemical shifts.
Navigation of Mobile Robots in Human Environments with Deep Reinforcement Learning (2016)

For mobile robots which operate in human environments it is not sufficient to simply travel to their target destination as quickly as possible. Instead, mobile robots in human environments need to travel to their destination safely, keeping a comfortable distance to humans and not colliding with any obstacles along the way. As the number of possible human-robot interactions is very large, defining a rule-based navigation approach is difficult in such highly dynamic environments. Current approaches solve this task by predicting the trajectories of humans in the scene and then planning a collision-free path. However, this requires separate components for detecting and predicting human motion and does not scale well to densely populated environments. Therefore, this work investigates the use of deep reinforcement learning for the navigation of mobile robots in human environments. This approach is based on recent research on utilizing deep neural networks in reinforcement learning to successfully play Atari 2600 video games on human level. A deep convolutional neural network is trained end-to-end from one-dimensional laser scan data to command velocities. Discrete and continuous action space implementations are evaluated in a simulation and are shown to outperform a Social Force Model baseline approach on the navigation problem for mobile robots in human environments.
Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants (2021)

Most mRNA-1273 vaccinated individuals maintained binding and functional antibodies against SARS-CoV-2 variants for 6 months.
Standard International Prognostic Index Remains a Valid Predictor of Outcome for Patients With Aggressive CD20<sup>+</sup>B-Cell Lymphoma in the Rituximab Era (2010)

The effects of rituximab were superimposed on the effects of CHOP with no interactions between chemotherapy and antibody therapy. These results demonstrate that the IPI is still valid in the R-CHOP era.
Molecular Shapes From Rotational Diffusion: Dye Molecules, Proteins And Nucleosomes (1988)

This paper examines the shape information available from measurements of fluorescence anisotropy decays. We report anisotropy decays for three systems and examine the kinds of information which may be obtained. Results for the dye rose bengal (~1000 dal-tons) suggest that an approximation used in rotational diffusion theory, that the solvent molecules are very small compared to the solute, is valid even for this relatively small molecule. Second, we examine the effects of calcium concentration on rotational diffusion of the protein calmodulin (~17,000 daltons) derivatized by crosslinking to form a dityrosine fluorophore. In the presence of sufficiently high calcium ion concentration, this crosslinked calmodulin shows a single exponential anisotropy decay which indicates rotational diffusion consistent with the extended dumbbell structure found for calmodulin by x-ray crystal-lography. At low calcium concentrations, th e crosslinked calmodulin rotates considerably faster, suggesting a much more compact shape; also, this anisotropy decay includes considerably shorter correlation times which are interpreted as arising from a segmental flexibility not evident for crosslinked calmodulin at high calcium concentration. Finally, we examine a transition which is observed at very low salt concentrations for nucleosome core particles, relatively large complexes (~200,000 daltons) derived from chromatin and comprised of eight histone molecules and 145 base pairs of DNA. The anisotropy decay of ethidium bound to the DNA indicates that core particles exposed to low ionic strength are considerably elongated relative to the shape at higher ionic strength.
Digital image processing system for LLLTV (2002)

In this paper, the implementation of an image processing system for low-light-level TV (LLLTV) is proposed with some new algorithms. To process the low light image sequences in real time, there are three functional modules, noise removal, local contrast enhancement and global histogram adjustment, in pipelining structures, which fully utilize the device resources and make the system practical for real time applications. The algorithms used can remove mixed noise, including Gaussian noise and impulsive noise, and enhance the local and the global contrast. In the field experiment, the system has proved to be very effective to improve the image quality.
Bacillus butanolivorans sp. nov., a species with industrial application for the remediation of n-butanol (2008)

Four bacterial strains, designated K9(T), K105, K1012A and K101, were isolated from soil in Lithuania. All these strains could use n-butanol as a sole carbon source. The strains grew in a medium containing 12-120 mM n-butanol. The strains were strictly aerobic, Gram-positive endospore-formers. The best growth was achieved at 25 degrees C and pH 7.0 in medium containing 1 % (w/v) NaCl. The strains showed identical profiles of 16S-23S rRNA internal transcribed spacer PCR and nearly identical 16S rRNA gene PCR-RFLP electrophoretic patterns and physiological characteristics, demonstrating their relationship at the species level. The cellular fatty acid profile of K9(T) consisted of significant amounts of the C(15) branched-chain fatty acids iso-C(15 : 0) (16.78 %) and anteiso-C(15 : 0) (45.80 %). The diagnostic cell-wall diamino acid was meso-diaminopimelic acid. The 16S rRNA gene sequence of K9(T) showed the highest similarity to the sequences of Bacillus simplex DSM 1321(T) and Bacillus muralis LMG 20238(T) (98.3 and 97.7 %, respectively). The DNA G+C content was 37.4 mol%. Studies of DNA-DNA relatedness, morphological, physiological and chemotaxonomic analyses and phylogenetic data based on 16S rRNA gene sequencing allowed strains K9(T), K105, K1012A and K101 to be described as members of a novel species of the genus Bacillus, for which the name Bacillus butanolivorans sp. nov. is proposed. The type strain is K9(T) (=DSM 18926(T) =LMG 23974(T)).
Double burst stimulation for monitoring neuromuscular blockade for tracheal intubation (1995)

Responses to double burst stimulation were palpated every 15 s after intravenous administration of vecuronium 0.2 mg.kg-1 in 60 adult patients under anaesthesia. Intubating conditions and neuromuscular responses to tracheal intubation were assessed at disappearance of one or both palpable responses to double burst stimulation in groups of 30 patients randomly divided, although in group A patients, tracheal intubation could be performed at disappearance of one palpable response to double burst stimulation; 27 out of 30 patients (90%) had mild to moderate bucking on intubation. In this group, only five patients (16.66%) had good intubating conditions. In group B, where tracheal intubation was attempted at disappearance of both palpable responses, intubating conditions were good in 28 out of 30 patients (93.33%) and there was no response to tracheal intubation in 26 out of 30 patients (86.66%). Palpation of evoked response to double burst stimulation can be used to predict intubating conditions and neuromuscular response to tracheal intubation with nondepolarising muscle relaxants such as vecuronium.
Synthesis of Phosphonate and Thiophosphonate Esters and Amides from Hydrogen-Phosphinates by a Novel One-Pot Activation-Coupling-Oxidation Procedure (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of Phosphonate and Thiophosphonate Esters and Amides from Hydrogen-Phosphinates by a Novel One-Pot Activation-Coupling-Oxidation ProcedureMaria de Fatima Fernandez, Cornelis P. Vlaar, Hong Fan, Yen-Hsiang Liu, Frank R. Fronczek, and Robert P. HammerCite this: J. Org. Chem. 1995, 60, 23, 7390–7391Publication Date (Print):November 1, 1995Publication History Published online1 May 2002Published inissue 1 November 1995https://pubs.acs.org/doi/10.1021/jo00128a006https://doi.org/10.1021/jo00128a006research-articleACS PublicationsRequest reuse permissionsArticle Views780Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Soldered double pancake winding of high temperature superconducting tape (2003)

To make a superconducting coil by winding a High Temperature Superconductor (HTS) tape conductor on a bobbin, the double pancake winding technique is widely used to reduce number of splicing contacts between conductor pieces. However, this makes some Ic (critical current) degradation on kink points of the conductors, which is unavoidable. Soldered double pancake can be an alternative way to overcome the Ic degradation. This paper describes and compares the two ways of winding; usual double pancake, and soldered double pancake. Characteristics of the windings are measured and compared. The soldered double pancake winding has resistance on the contact points, but the estimated Joule heating on the contacts is much smaller than heat leak of cryostats.
Fluoride Ion Complexation and Sensing Using Organoboron Compounds (2010)

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTFluoride Ion Complexation and Sensing Using Organoboron CompoundsCasey R. Wade†, Alexander E. J. Broomsgrove‡, Simon Aldridge*‡, and François P. Gabbaï*†View Author Information Chemistry Department, Texas A&M University, 3255 TAMU, College Station, Texas 77843-3255, and Inorganic Chemistry, University of Oxford, South Parks Road, Oxford OX1 3QR, United Kingdom* To whom correspondence should be addressed. E-mail: [email protected] (S.A.) and [email protected] (F.P.G.).†Texas A&M University.‡University of Oxford.Cite this: Chem. Rev. 2010, 110, 7, 3958–3984Publication Date (Web):June 11, 2010Publication History Received11 December 2009Published online11 June 2010Published inissue 14 July 2010https://pubs.acs.org/doi/10.1021/cr900401ahttps://doi.org/10.1021/cr900401areview-articleACS PublicationsCopyright © 2010 American Chemical SocietyRequest reuse permissionsArticle Views11538Altmetric-Citations993LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Anions,Boron,Group 13 compounds,Inorganic compounds,Receptors Get e-Alerts
Quantitative Methods in Credit Management: A Survey (1994)

Many static and dynamic models have been used to assist decision making in the area of consumer and commercial credit. The decisions of interest include whether to extend credit, how much credit to extend, when collections on delinquent accounts should be initiated, and what action should be taken. We survey the use of discriminant analysis, decision trees, and expert systems for static decisions, and dynamic programming, linear programming, and Markov chains for dynamic decision models. Since these models do not operate in a vacuum, we discuss some important aspects of credit management in practice, e.g., legal considerations, sources of data, and statistical validation of the methodology. We provide our perspective on the state-of-the-art in theory and in practice.
Thermophysics Characterization of Kerosene Combustion (2001)

A one-formula surrogate fuel formulation and its quasi-global combustion kinetics model are developed to support the design of injectors and thrust chambers of kerosene-fueled rocket engines. This surrogate fuel model depicts a fuel blend that properly represents the general physical and chemical properties of kerosene. The accompanying gaseous-phase thermodynamics of the surrogate fuel is anchored with the heat of formation of kerosene and verified by comparing a series of one-dimensional rocket thrust chamber calculations. The quasi-global combustion kinetics model consists of several global steps for parent fuel decomposition, soot formation, and soot oxidation and a detailed wet-CO mechanism to complete the combustion process. The final thermophysics formulations are incorporated with a computational fluid dynamics model for prediction of the combustion efficiency of an unielement, tripropellant combustor and the radiation of a kerosene-fueled thruster plume. The model predictions agreed reasonably well with those of the tests.
State of the art and best practices for optical network self monitoring and optimization (2019)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text M. Lyonnais, "State of the art and best practices for optical network self monitoring and optimization," in Optical Fiber Communication Conference (OFC) 2019, OSA Technical Digest (Optica Publishing Group, 2019), paper Th1G.5. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Erythroid Krüppel-like factor is recruited to the CACCC box in the β-globin promoter but not to the CACCC box in the γ-globin promoter: The role of the neighboring promoter elements (2000)

The programmed expression of the five beta-like globin genes (epsilon, (A)gamma, (G)gamma, delta, and beta) is characterized by a series of switches that are developmentally regulated. The (A)gamma- and (G)gamma- (fetus) to beta-globin (adult) switch depends on transcription factor erythroid Krüppel-like factor (EKLF), which, like Sp1, binds to CACCC boxes. EKLF is essential for the expression of the beta-globin but not the gamma-globin gene. Because both gamma-globin and beta-globin promoters contain the CACCC box, and their promoter elements are similar, it is not known why the two promoters behave so differently. In this report, we searched for the functional differences between the two promoters by studying their ability to recruit EKLF. We used the in vivo PIN*POINT assay to show that EKLF is recruited to the beta-globin promoter but not to the gamma-globin promoter. We show that this selectivity is a result of differences in surrounding promoter elements and not CACCC box alone. One of the differences between the two promoters with a functional consequence is the CCTTG repeat that is present in the gamma-globin promoter but not in the beta-globin promoter. The repeat, when inserted in the beta-globin promoter, decreases EKLF recruitment to and activity of the beta-globin promoter, suggesting that the repeat functions as a suppressor element. The CCTTG repeat can also suppress the SV40 promoter in cis, and the suppressor factor binding to the repeat can be squelched with a plasmid containing a high copy number of the repeat. These findings may have implications in designing drug targets for treatment of beta-globin disorders.
Circulating microRNAs as Biomarkers for Detection of Autologous Blood Transfusion (2013)

MicroRNAs (miRNAs) are small non-coding RNAs that regulate various biological processes. Cell-free miRNAs measured in blood plasma have emerged as specific and sensitive markers of physiological processes and disease. In this study, we investigated whether circulating miRNAs can serve as biomarkers for the detection of autologous blood transfusion, a major doping technique that is still undetectable. Plasma miRNA levels were analyzed using high-throughput quantitative real-time PCR. Plasma samples were obtained before and at several time points after autologous blood transfusion (blood bag storage time 42 days) in 10 healthy subjects and 10 controls without transfusion. Other serum markers of erythropoiesis were determined in the same samples. Our results revealed a distinct change in the pattern of circulating miRNAs. Ten miRNAs were upregulated in transfusion samples compared with control samples. Among these, miR-30b, miR-30c, and miR-26b increased significantly and showed a 3.9-, 4.0-, and 3.0-fold change, respectively. The origin of these miRNAs was related to pulmonary and liver tissues. Erythropoietin (EPO) concentration decreased after blood reinfusion. A combination of miRNAs and EPO measurement in a mathematical model enhanced the efficiency of autologous transfusion detection through miRNA analysis. Therefore, our results lay the foundation for the development of miRNAs as novel blood-based biomarkers to detect autologous transfusion.
Identification of the UMP Synthase Gene by Establishment of Uracil Auxotrophic Mutants and the Phenotypic Complementation System in the Marine Diatom<i>Phaeodactylum tricornutum</i>      (2011)

Uridine-5'-monophosphate synthase (UMPS), the critical step of the de novo pyrimidine biosynthesis pathway, which is a housekeeping plastid process in higher plants, was investigated in a marine diatom, the most crucial primary producer in the marine environment. A mutagenesis using an alkylation agent, N-ethyl-N-nitrosourea, was carried out to the marine diatom Phaeodactylum tricornutum. Cells were treated with 1.0 mg mL(-1) N-ethyl-N-nitrosourea and were screened on agar plates containing 100 to 300 mg L(-1) 5-fluoroorotidic acid (5-FOA). Two clones survived the selection and were designated as Requiring Uracil and Resistant to FOA (RURF) 1 and 2. The 50% effective concentration of 5-FOA on growth of RURF1 was about 5 mm, whereas that in wild-type cells was 30 μm. The ability to grow in the absence of uracil was restored by a P. tricornutum gene that potentially encoded UMPS or the human umps gene, HUMPS. Because the P. tricornutum gene was able to restore growth in the absence of uracil, it was designated as ptumps, encoding a major functional UMPS in P. tricornutum. RNA interference to the ptumps targeting the 5' region of ptumps resulted in the occurrence of a clear RURF phenotype in P. tricornutum. This RNA interference phenotype was reverted to the wild type by the insertion of HUMPS, confirming that the ptumps encodes UMPS. These results showed direct evidence of the occurrence of novel-type UMPS in a marine diatom and also revealed the potential usage of this gene silencing and complementation system for molecular tools for this organism.
Molecular characterization of proteins in detergent solutions (1974)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMolecular characterization of proteins in detergent solutionsCharles Tanford, Yashiko Nozaki, Jacqueline A. Reynolds, and Shio MakinoCite this: Biochemistry 1974, 13, 11, 2369–2376Publication Date (Print):May 1, 1974Publication History Published online1 May 2002Published inissue 1 May 1974https://pubs.acs.org/doi/10.1021/bi00708a021https://doi.org/10.1021/bi00708a021research-articleACS PublicationsRequest reuse permissionsArticle Views704Altmetric-Citations380LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts