gebhart/patrepeval huggingface dataset:
GH-Secretion Capacity in Turner Syndrome and its Relations to Clinical Characteristics and Effect of GH Treatment (1991)

The relations of GH secretion capacity by stimulation tests to clinical characteristics and the effect of GH treatment were studied in 151 girls with Turner syndrome and were compared with those in 128 patients with pituitary dwarfism. GH secretion capacity expressed by mean peak GH was not associated with clinical characteristics related to growth such as height SDS and growth velocity SDS in Turner syndrome and was influenced by % overweight, whereas it was associated with growth-related clinical characteristics in pituitary dwarfism. Because GH secretion capacity does not affect growth in Turner syndrome, it is not reasonable to diagnose low peak GH in stimulation tests as GH deficiency in Turner syndrome. GH treatment increased the growth velocity and growth velocity SD score in Turner syndrome in a dose-dependent manner. In pituitary dwarfism, the effect of GH treatment expressed by the increase in growth velocity SD score had a negative correlation with growth velocity SD score before GH treatment and GH secretion capacity, which indicated that GH treatment was replacement therapy. In Turner syndrome, the effect of GH treatment had a negative correlation with growth velocity and growth velocity SD score before GH treatment, but had no relation to GH secretion capacity, which suggested that GH treatment did not provide replacement GH but had another pharmacological effect.
Measurement Noise Recommendation for Efficient Kalman Filtering over a Large Amount of Sensor Data (2019)

To effectively maintain and analyze a large amount of real-time sensor data, one often uses a filtering technique that reflects characteristics of original data well. This paper proposes a novel method for recommending the <i>measurement noise</i> for Kalman filtering, which is one of the most representative filtering techniques. Kalman filtering corrects inaccurate values of input sensor data, and its filtering performance varies depending on the input noise parameters. In particular, if the noise parameters determined based on the user's experience are incorrect, the accuracy of Kalman filtering may be reduced significantly. Based on this observation, this paper addresses how to determine the measurement noise variance, a major input parameter of Kalman filtering, by analyzing past sensor data and how to use the estimated noise to improve the filtering accuracy. More specifically, to estimate the measurement noise variance, two analytical methods are proposed: one a <i>transform-based</i> method using a <i>wavelet</i> transform and the other a <i>learning-based</i> method using a <i>denoising autoencoder</i>. Experimental results show that the proposed methods estimated the measurement noise variance accurately and were superior to the experience-based method in the filtering accuracy.
Runtime Neural Pruning (2017)

In this paper, we propose a Runtime Neural Pruning (RNP) framework which prunes the deep neural network dynamically at the runtime. Unlike existing neural pruning methods which produce a fixed pruned model for deployment, our method preserves the full ability of the original network and conducts pruning according to the input image and current feature maps adaptively. The pruning is performed in a bottom-up, layer-by-layer manner, which we model as a Markov decision process and use reinforcement learning for training. The agent judges the importance of each convolutional kernel and conducts channel-wise pruning conditioned on different samples, where the network is pruned more when the image is easier for the task. Since the ability of network is fully preserved, the balance point is easily adjustable according to the available resources. Our method can be applied to off-the-shelf network structures and reach a better tradeoff between speed and accuracy, especially with a large pruning rate.
Sleep disturbances in depressed pregnant women and their newborns (2006)

Pregnant women (N=253) were recruited during their second trimester of pregnancy (M=22.3 weeks gestation) and assigned to depressed (N=83) and non-depressed groups based on a SCID diagnosis of depression. They were then given self-report measures on sleep disturbance, depression, anxiety and anger, and their urine was assayed for norepinephrine and cortisol. These measures were repeated during their third trimester (M=32.4 weeks). Their newborns were then observed during sleep. During both the second and third trimesters, the depressed women had more sleep disturbances and higher depression, anxiety and anger scores. They also had higher norepinephrine and cortisol levels. The newborns of the depressed mothers also had more sleep disturbances including less time in deep sleep and more time in indeterminate (disorganized) sleep, and they were more active and cried/fussed more.
General Anesthesia Inhibits the Activity of the “Glymphatic System” (2017)

<b>INTRODUCTION:</b> According to the "glymphatic system" hypothesis, brain waste clearance is mediated by a continuous replacement of the interstitial milieu by a bulk flow of cerebrospinal fluid (CSF). Previous reports suggested that this cerebral CSF circulation is only active during general anesthesia or sleep, an effect mediated by the dilatation of the extracellular space. Given the controversies regarding the plausibility of this phenomenon and the limitations of currently available methods to image the glymphatic system, we developed original whole-brain <i>in vivo</i> imaging methods to investigate the effects of general anesthesia on the brain CSF circulation. <b>METHODS:</b> We used magnetic resonance imaging (MRI) and near-infrared fluorescence imaging (NIRF) after injection of a paramagnetic contrast agent or a fluorescent dye in the cisterna magna, in order to investigate the impact of general anesthesia (isoflurane, ketamine or ketamine/xylazine) on the intracranial CSF circulation in mice. <b>RESULTS:</b><i>In vivo</i> imaging allowed us to image CSF flow in awake and anesthetized mice and confirmed the existence of a brain-wide CSF circulation. Contrary to what was initially thought, we demonstrated that the parenchymal CSF circulation is mainly active during wakefulness and significantly impaired during general anesthesia. This effect was especially significant when high doses of anesthetic agent were used (3% isoflurane). These results were consistent across the different anesthesia regimens and imaging modalities. Moreover, we failed to detect a significant change in the brain extracellular water volume using diffusion weighted imaging in awake and anesthetized mice. <b>CONCLUSION:</b> The parenchymal diffusion of small molecular weight compounds from the CSF is active during wakefulness. General anesthesia has a negative impact on the intracranial CSF circulation, especially when using a high dose of anesthetic agent.
Ball-Stick-Bird: Teaching with the Story Engram. (1990)

This paper describes the Ball-Stick-Bird reading system, which shows students how all the letters of the alphabet can be built with three basic forms: a circle (ball), a line (stick), and an angle (bird). The method also uses modified phonics and developmental linguistics, aids reading by using capital letters in the beginning, and enhances comprehension by laying out the in idea units. Successful use of the system with individuals with various disabilities is documented. Evidence that low intelligence subjects were able to learn to read advanced material with comprehension and to write stories led to development of a new paradigm of cognitive/neurological organization. This paradigm views comprehension as so fundamental and overrepresented in the human brain that even a severely damaged brain can almost always call on this capacity. The fundamental unit of cognitive organization is the idea unit, which is actually a miniature story. The Ball-Stick-Bird method mimics the developmental process, by using idea units to build bigger stories. The idea unit, termed the story engram, functions as a cognitive organizer and therefore structures conscious reality. As students learned to use the engram to build bigger stories, they matured far beyond expectations because, having learned to impose a structure on the world around them, they saw themselves as having acquired a structure, an identity. (JDD) *********************************************************************** Reproductions supplied by EDRS are the best that can be made from the original document. *********************************************************************** J. of the Society for Accelerative Learning and Teaching, tr) 1990, 15 (1&2) CM Ball-Stick-Bird: Teaching with the Story Engram
Learning weighted naive Bayes with accurate ranking (2004)

Naive Bayes is one of most effective classification algorithms. In many applications, however, a ranking of examples are more desirable than just classification. How to extend naive Bayes to improve its ranking performance is an interesting and useful question in practice. Weighted naive Bayes is an extension of naive Bayes, in which attributes have different weights. This paper investigates how to learn a weighted naive Bayes with accurate ranking from data, or more precisely, how to learn the weights of a weighted naive Bayes to produce accurate ranking. We explore various methods: the gain ratio method, the hill climbing method, and the Markov chain Monte Carlo method, the hill climbing method combined with the gain ratio method, and the Markov chain Monte Carlo method combined with the gain ratio method. Our experiments show that a weighted naive Bayes trained to produce accurate ranking outperforms naive Bayes.
Progression of Aleutian disease in natural and experimentally induced infections of mink (1996)

After infection, leukocyte viral DNA is initially present in large amounts, but, in most mink, decreases markedly in association with the appearance of antibody. There is no difference in the progression and severity of the disease between black mink infected experimentally or naturally. Transmission of the disease may be enhanced by use of contaminated toenail clippers for blood collection.
Example-based facial rigging (2010)

I work at the intersection between Computer Graphics, Computer Vision, and AI, with focus on photorealistic human digitization using deep learning and data-driven techniques.I'm known for my work on dynamic geometry processing, virtual avatar creation, facial performance capture, AI-driven 3D shape digitization, and deep fakes.My research has led to the Animoji technology in Apple's iPhone X, I worked on the digital reenactment of Paul Walker in the movie Furious 7, and my algorithms on deformable shape alignment have improved the radiation treatment for cancer patients all over the world.I have been keynote speaker at numerous major events, conferences, festivals, and universities, including the World Economic Forum (WEF) in Davos 2020 and Web Summit 2020.
Quantifying Ligand Exchange Reactions at CdSe Nanocrystal Surfaces (2016)

The exchange reactions of X-type ligands at the surface of CdSe nanocrystals have been quantified via 1H NMR, absorbance, and emission spectroscopies. 1H NMR was used to quantify displacement reactions of oleate-capped CdSe nanocrystals with carboxylic-acid-, phosphonic-acid-, and thiol-terminated ligands that incorporate terminal alkene functionalities. The alkenyl protons of the native oleate ligand and the vinylic protons of the exchange ligand provide spectroscopic handles to quantify both free and surface-bound forms of these ligands. Undec-10-enoic acid was found to undergo an exchange equilibrium with oleate (Keq = 0.83), whereas phosphonic-acid- and thiol-terminated ligands irreversibly displace native oleate ligands. Absorption and emission experiments indicate that the carboxylic acid exchanges occur solely between surface-bound ligands, whereas exchange reactions with phosphonic acids and thiols alter the surface metal atoms of the nanocrystals, presumably through the displacement of Cd(oleate)2. These quantifications can be used to guide the selective functionalization of CdSe nanocrystals.
Quantum Dot FRET-Based Probes in Thin Films Grown in Microfluidic Channels (2010)

This paper describes the development of new fluorescence resonance energy transfer (FRET)-based quantum dot probes for proteolytic activity. The CdSe/ZnS quantum dots are incorporated into a thin polymeric film, which is prepared by layer-by-layer deposition of alternately charged polyelectrolytes. The quantum dots, which serve as fluorescent donors, are separated from rhodamine acceptor molecules, which are covalently attached to the film surface by a varying number of polyelectrolyte layers. When excited with visible light, the emission color of the polyelectrolyte multilayer film appears orange due to FRET between the quantum dots and molecular acceptors. The emission color changes to green when the rhodamine molecules are removed from the surface by enzymatic cleavage. The new probe design enables the use of quantum dots in bioassays, in this study for real-time monitoring of trypsin activity, while alleviating concerns about their potential toxicity. Application of these quantum dot FRET-based probes in microfluidic channels enables bioanalysis of volume-limited samples and single-cell studies in an in vivo-like environment.
Mediators of inflammation (1997)

Therapeutic studies and genetically engineered animals have elucidated the inflammatory roles of cytokines and chemokines in autoimmune disease. Most unexpected has been a continuum of recent evidence demonstrating that inflammatory mediators are crucial in lymphoid organ development, thus suggesting that these hitherto unrelated processes have common elements with implications for determinant spreading.
Heterogeneously catalyzed etherification of glycerol: new pathways for transformation of glycerol to more valuable chemicals (2008)

Direct etherification of glycerol with alkyl alcohols, olefins and dibenzyl ethers was successfully catalyzed by acid functionalized silica, allowing the first catalytic access to valuable monoalkyl glyceryl ethers.
Metal‐Mediated Synthesis of Multidomain Ligands—A New Strategy for Metallosupramolecular Chemistry (1995)

Abstract The bridging ligand bis{4′‐(2,2′:6′,2″‐terpyridinyl)}ether ( 1 ) can be prepared in 69% yield from the reaction of 4′‐chloro‐2,2′:6′,2″‐terpyridine ( 3 ) with 2,2′:6′,2″‐terpyridin‐4′(1′ H )‐one ( 2 ) in Me 2 NCHO in the presence of KOH. More conveniently, complexes of 1 can be prepared in situ by the reaction of 2 with a ruthenium(II) complex of 3 in the presence of K 2 CO 3 . This methodology has been developed for the synthesis of a range of mono‐, di‐, tri‐ and hexanuclear complexes with a variety of Xtpy (Xtpy = 4′‐substituted 2,2′:6′,2″‐terpyridine) terminator ligands. The molecular structure of 1 ( a = 9.623(2), b = 11.241(1), c = 11.828(1) Å; space group P 1 ; α = 93.064(9), β = 107.072(14), γ = 99.088(14)°; Z = 2, R = 0.0450, R w = 0.0577) has been determined. The generality of the methodology may ultimately be limited by the sensitivity of the ether‐linkage in 1 to attack by nucleophiles.
An EEPROM cell using a low barrier height tunnel oxide (1986)

A new simple method to fabricate a thin oxide with low barrier height is proposed. An oxide is grown on a heavily implanted silicon substrate with As or P in excess of 5 × 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">14</sup> /cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . When the oxide was grown in H <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> O + Ar gas after Ar annealing, the barrier height of the oxide conduction band with respect to the silicon conduction band decreased to 1.8 eV, about one half of the ordinary value of 3.2 eV. This phenomenon was applied to an EEPROM cell, which showed superior WRITE/ERASE characteristics. A moderately implanted As (2.5 × 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">15</sup> / cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> ) sample shows excellent WRITE/ERASE endurance, over 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sup> cycles with 2-V V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</inf> window, which could not realized by using an ordinary oxide.
Virtual display with low-power-consuming, portable microprojector (2003)

This paper displays the first prototype for a very low power consuming and portable micro projector. The described prototype may be integrated in a vast set of applications such as a screen alternative device in a portable computer or a cellular phone. The low power consumption is critical factor for such application in order to allow operation from the portable battery of the above-mentioned devices. The paper presents and discussed the vast set of possible applications as well as the prototype’s measured technical set of performance.
Reactivity of tetracyanoethylene oxide toward heteroaromatic compounds. Synthesis and structure of heterocyclic dicyanomethylides (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactivity of tetracyanoethylene oxide toward heteroaromatic compounds. Synthesis and structure of heterocyclic dicyanomethylidesEnrique Diez-Barra, Maria Del Carmen Pardo, and Jose ElgueroCite this: J. Org. Chem. 1982, 47, 23, 4409–4412Publication Date (Print):November 1, 1982Publication History Published online1 May 2002Published inissue 1 November 1982https://pubs.acs.org/doi/10.1021/jo00144a004https://doi.org/10.1021/jo00144a004research-articleACS PublicationsRequest reuse permissionsArticle Views231Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Electromagnetics in Petroleum Prospecting: Top Researcher’s Forecast (1983)

In the implicit superbness of their sheepskins (always framed by recipients) Princeton is said to be to linguistics what Harvard is to business. Following this parallel, collegiate humor has exalted the Colorado School of Mines to The Princeton of Petroleum and The Harvard of Hard Rocks. Trite alliterations aside, it is one of the universities of mineral resources. And among geophysicists, the comment, “Ah — you went to Mines?” — is one of admiration. Why? Counted in the reasons is the fact that 119-year-old institution offered in 1927 the first course in applied geophysics given in the US. It was on a January morning when seven students heard Dr. Carl Heiland begin a discussion on the applications of the torsion balance to petroleum exploration. CSM’s geophysics department, then headed by that lone professor, had been created only five months before, at the insistence of the geology department chief, F. M. Van Tuyl.
Role of Gastric Mucosal Eicosanoid Production in the Cytoprotection Induced by Nitecapone (1992)

Nitecapone (3-100 mg/kg orally) dose-dependently (40-97%) decreased the macroscopic gastric lesions induced by ethanol, NaOH, or HCl in the rat. The duration of protection was long, being still 70% at 6 h after dosing. Nitecapone (10-100 mg/kg orally) induced at 1 h after dosing a significant and dose-dependent increase in gastric mucosal prostaglandin E2 release. After the dose of 30 mg/kg the release was sixfold at 2 h and threefold at 12 h. Colloidal bismuth subcitrate (30 mg/kg) stimulated the prostaglandin E2 release only transiently, and sucralfate (400 mg/kg) showed only a tendency to stimulate the release. Indomethacin prevented the nitecapone-induced stimulation of prostaglandin E2 but was unable to counteract the cytoprotective activity of the compound. Nitecapone (30 mg/kg) also caused transient increase (twofold) in the release of 6-keto-prostaglandin F1 alpha and thromboxane B2 and a decrease in both basal and ethanol-induced release of leukotriene C4.
HYBRID EFFECT IN NATURAL CELL-MEDIATED CYTOTOXICITY OF SV40-TRANSFORMED FIBROBLASTS BY RAT SPLEEN CELLS (1977)

Hardie, Ian; Balderson, Glenda; Hamlyn, Lizzi; McKay, Dorothy; Clunie, Gordon Author Information
Secondary Intervention After Endovascular Abdominal Aortic Aneurysm Repair (2009)

Although 2ndINT are common after EVAR, most were addressed through an endovascular approach; technical success thereof varies widely with the specific indication for 2ndINT. Secondary intervention did not adversely affect aneurysm-related or overall actuarial 5-year survival.
Fast modeling of core switching noise on distributed LRC power grid in ULSI circuits (2002)

A sophisticated on-chip power grid model consisting of distributed LRC elements is proposed for on-chip power distribution analysis. Fast equations for peak noise estimations are formulated. Noise distribution on a power grid with any topology is efficiently and accurately computed. HSPICE simulations confirmed its efficiency and accuracy. The model is suitable for both early stage analysis and post-layout verifications in on-chip power distribution design. Global and local optimization such as buffer sizing, power bus sizing, and on-chip decoupling capacitor placement can be easily conducted.
Double loop guiding catheter: A primary catheter for angioplasty of the right coronary artery (1988)

Double loop guiding catheters have been used for percutaneous transluminal coronary angioplasty (PTCA) of the right coronary artery (RCA) in 42 consecutive cases. A catheter with a 90-degree primary curve was used when the proximal RCA had horizontal or inferior orientation. When the proximal segment of the RCA was oriented superiorly (shepherd's crook), the catheter with a 75-degree primary curve was used. Catheters were fabricated with short (1.5 cm) or long (2.3 cm) (USCI, C.R. Bard, Inc., Billerica, MA) distal tips. Short-tip catheters were satisfactory in the majority of cases. When the RCA had a complex course and more backup was necessary or when the ascending aorta was wide, long-tip catheters were found to be the best choice. Angioplasty of 49 lesions was attempted in 42 consecutive patients. In 39 patients successful dilatation was achieved (93%). In three patients the procedure was unsuccessful. In one patient, the lesion could not be crossed with the guidewire despite an excellent backup. In another patient, two of three stenoses were dilated successfully; the distal lesion was crossed with a guidewire but could not be crossed with the balloon catheter in spite of a good backup. The lack of a satisfactory engagement and inadequate backup were responsible for the failure in only one patient. There were no complications related to these guiding catheters. We conclude that double loop guiding catheters are safe and can be the primary choice in all right coronary angioplasties. These catheters provide an excellent backup with consequent high success rate.