gebhart/patrepeval huggingface dataset:
Fully-Convolutional Point Networks for Large-Scale Point Clouds (2018)

This work proposes a general-purpose, fully-convolutional network architecture for efficiently processing large-scale 3D data. One striking characteristic of our approach is its ability to process unorganized 3D representations such as point clouds as input, then transforming them internally to ordered structures to be processed via 3D convolutions. In contrast to conventional approaches that maintain either unorganized or organized representations, from input to output, our approach has the advantage of operating on memory efficient input data representations while at the same time exploiting the natural structure of convolutional operations to avoid the redundant computing and storing of spatial information in the network. The network eliminates the need to pre- or post process the raw sensor data. This, together with the fully-convolutional nature of the network, makes it an end-to-end method able to process point clouds of huge spaces or even entire rooms with up to 200k points at once. Another advantage is that our network can produce either an ordered output or map predictions directly onto the input cloud, thus making it suitable as a general-purpose point cloud descriptor applicable to many 3D tasks. We demonstrate our network's ability to effectively learn both low-level features as well as complex compositional relationships by evaluating it on benchmark datasets for semantic voxel segmentation, semantic part segmentation and 3D scene captioning.
Genetic Haplotyping of Ataxia-telangiectasia Families Localizes the Major Gene to an ∼ 850 kb Region on Chromosome 11q23.1 (1994)

The genotyping data given localize the major A-T gene to an ∼ 850 kb region. They also localize the group A A-T gene (ATA) to a region that contains the ∼ 850 kb region. They are compatible with linking A-TFresno to 11q22–23. NBS-V2 does not link to this region. Four non-linking families contain only single affecteds, suggesting that these may be spontaneous mutations rather than evidence for an A-T gene outside the 11q22–23 region. Finally, two other non-linking families contain recombinant haplotypes that are compatible with a second A-T gene at 11q22-23, slightly distal to the ∼ 850 kb region. However, convincing evidence for a second gene is still lacking.
Comprehensive Survey of IoT, Machine Learning, and Blockchain for Health Care Applications: A Topical Assessment for Pandemic Preparedness, Challenges, and Solutions (2021)

Internet of Things (IoT) communication technologies have brought immense revolutions in various domains, especially in health monitoring systems. Machine learning techniques coupled with advanced artificial intelligence techniques detect patterns associated with diseases and health conditions. Presently, the scientific community is focused on enhancing IoT-enabled applications by integrating blockchain technology with machine learning models to benefit medical report management, drug traceability, tracking infectious diseases, etc. To date, contemporary state-of-the-art techniques have presented various efforts on the adaptability of blockchain and machine learning in IoT applications; however, there exist various essential aspects that must also be incorporated to achieve more robust performance. This study presents a comprehensive survey of emerging IoT technologies, machine learning, and blockchain for healthcare applications. The reviewed articles comprise a plethora of research articles published in the web of science. The analysis is focused on research articles related to keywords such as ‘machine learning’, blockchain, ‘Internet of Things or IoT’, and keywords conjoined with ‘healthcare’ and ‘health application’ in six famous publisher databases, namely IEEEXplore, Nature, ScienceDirect, MDPI, SpringerLink, and Google Scholar. We selected and reviewed 263 articles in total. The topical survey of the contemporary IoT-based models is presented in healthcare domains in three steps. Firstly, a detailed analysis of healthcare applications of IoT, blockchain, and machine learning demonstrates the importance of the discussed fields. Secondly, the adaptation mechanism of machine learning and blockchain in IoT for healthcare applications are discussed to delineate the scope of the mentioned techniques in IoT domains. Finally, the challenges and issues of healthcare applications based on machine learning, blockchain, and IoT are discussed. The presented future directions in this domain can significantly help the scholarly community determine research gaps to address.
Preparation and 13C NMR Spectroscopic Study of Disubstituted Adamantane-1,3-dimethyldiyl Dications (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation and 13C NMR Spectroscopic Study of Disubstituted Adamantane-1,3-dimethyldiyl DicationsMichael D. Heagy, Qi Wang, George A. Olah, and G. K. Surya PrakashCite this: J. Org. Chem. 1995, 60, 22, 7351–7354Publication Date (Print):November 1, 1995Publication History Published online1 May 2002Published inissue 1 November 1995https://pubs.acs.org/doi/10.1021/jo00127a049https://doi.org/10.1021/jo00127a049research-articleACS PublicationsRequest reuse permissionsArticle Views235Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Signal gain saturation in two-channel common amplification using a 1.5μm InGaAsP travelling-wave laser amplifier (1987)

Signal gain saturation and crosstalk characteristics in two-channel common amplification were investigated using a 1.5μm travelling-wave laser amplifier. Simultaneous amplification in the two channels causes gain saturation of the other, which results in an approximate 3 dB reduction in saturation output power. The total output power is confirmed to dominate the gain saturation in laser amplifiers.
Spatial and Temporal Enhancement of Depth Images Captured by a Time-of-Flight Depth Sensor (2010)

In this paper, we present a new method to enhance depth images captured by a time-of-flight (TOF) depth sensor spatially and temporally. In practice, depth images obtained from TOF depth sensors have critical problems, such as optical noise existence, unmatched boundaries, and temporal inconsistency. In this work, we improve depth quality by performing a newly-designed joint bilateral filtering, color segmentation-based boundary refinement, and motion estimation-based temporal consistency. Experimental results show that the proposed method significantly minimizes the inherent problems of the depth images so that we can use them to generate a dynamic and realistic 3D scene.
Marginal Expense Oil Well Wireless Monitoring (2000)

Abstract Wireless surveillance of rod pumped oil wells has typically involved mating high power radios with pump off controllers. These combinations are very effective but economic application is limited due to cost. A need exists for a simpler wireless surveillance system that can be economically applied to stripper wells. Continued breakthroughs in the technology sector have lead to lowered cost and improved quality for a variety of electronic components. This study involves a low cost, small, self-contained wireless vibration surveillance unit that can be bolted directly to the pumping unit. The device includes a shear-sensing transducer, battery, pre-programmed microchip, and low power radio transmitter. Signals related to the vibration behavior of the pumping unit are transmitted to a base station computer that will indicate an alarm condition when the well deviates from normal, pumped off performance.
THE CHRISTIAN IMPERATIVE (1951)

THE CHRISTIAN IMPERATIVE Get access FLOYD H. ROSS FLOYD H. ROSS Search for other works by this author on: Oxford Academic Google Scholar Journal of the American Academy of Religion, Volume XIX, Issue 1, January 1951, Pages 3–5, https://doi.org/10.1093/jaarel/XIX.1.3 Published: 01 January 1951
Hitting the bull’s eye: targeting HMGA1 in cancer stem cells (2014)

Emerging evidence suggests that when cancer cells hijack normal stem cell properties, they acquire the ability to invade, metastasize to distant sites and evade therapy. Thus, eliminating cancer cells with stem cell properties, or cancer stem cells, is of prime importance for the successful treatment of cancer, regardless of the tissue of origin. Previous efforts to target cancer stem cells (CSCs), however, have been largely unsuccessful. Recent studies led to the discovery of a novel role for the high mobility group A1 (HMGA1) protein as a master regulator in both CSCs and normal embryonic stem cells. Here, we present exciting new work unveiling HMGA1 as a promising target for therapies directed at eradicating CSCs.
Suppression of Late Reverberation Effect on Speech Signal Using Long-Term Multiple-step Linear Prediction (2009)

A speech signal captured by a distant microphone is generally smeared by reverberation, which severely degrades automatic speech recognition (ASR) performance. One way to solve this problem is to dereverberate the observed signal prior to ASR. In this paper, a room impulse response is assumed to consist of three parts: a direct-path response, early reflections and late reverberations. Since late reverberations are known to be a major cause of ASR performance degradation, this paper focuses on dealing with the effect of late reverberations. The proposed method first estimates the late reverberations using long-term multi-step linear prediction, and then reduces the late reverberation effect by employing spectral subtraction. The algorithm provided good dereverberation with training data corresponding to the duration of one speech utterance, in our case, less than 6 s. This paper describes the proposed framework for both single-channel and multichannel scenarios. Experimental results showed substantial improvements in ASR performance with real recordings under severe reverberant conditions.
Novel retroviral vectors for efficient expression of the multidrug resistance (mdr-1) gene in early hematopoietic cells (1995)

We present data that retroviral gene expression in early hematopoietic cells is subjected to transcriptional controls similar to those previously described for embryonic stem cells. Transient transfection experiments revealed that both the viral enhancer region in the U3 region of the long terminal repeat as well as a repressor element coincident with the primer binding site of Moloney leukemia viruses are limiting for expression in hematopoietic cells in a differentiation-dependent manner. Within the group of Moloney leukemia virus-related viruses, only the myeloproliferative sarcoma virus showed high enhancer activity in myeloid (including erythroid) cells. In contrast, enhancer regions related to the Friend mink cell focus-forming viruses mediate much higher gene expression levels in both multipotent and lineage-committed myeloid cells. In addition, transcriptional repression related to sequences in the primer binding site of Moloney leukemia virus-derived vectors is also found in early hematopoietic cells and can be overcome by using the corresponding sequences of the murine embryonic stem cell virus. On the basis of these results, two types of novel retroviral hybrid vectors were developed; they combine the U3 regions of either the Friend mink cell focus-forming virus family or the myeloproliferative sarcoma virus with the primer binding site of the murine embryonic stem cell virus. When used to express the human multiple drug resistance gene, these vectors substantially improve protection to cytostatic drugs in transduced hematopoietic cell lines FDC-Pmix, TF-1, and K-562 in comparison with Moloney leukemia virus-derived vectors presently used for the stem cell protection approach in somatic gene therapy.
An Accurate Multiphase Upscaling for Flow and Transport in Heterogeneous Porous Media (2007)

Abstract Subgrid effects can have a strong influence on flow and transport in oil reservoirs. In this work a new model for the representation of subgrid terms is introduced and applied to two-phase reservoir flows. The model entails a construction of pseudo relative permeabilities using accurate inlet boundary conditions for the saturation field. Motivation for the form of the model is provided through a consideration of asymptotic techniques for two-phase flow. The numerical computation of the subgrid terms and the implementation of the overall method are described. The accuracy of the new subgrid representation is compared to that of coarse scale models with no subgrid treatment and to coarse models based on traditional pseudo relative permeabilities. In essentially all cases the new model provides more accurate coarse scale predictions relative to reference fine scale results. These are preliminary results.
Interactions of formylmethionyl‐leucyl‐phenylalanine, adenosine, and phosphodiesterase inhibitors in human monocytes Effects on superoxide release, inositol phosphates and cAMP (1989)

Cessation of the fMLF-induced burst of human monocyte superoxide release was associated with a rise in cAMP. This was not due to inhibition of phosphodiesterase (PDE), the major form of which was the PDE IV isozyme. The action of burst inhibitors did not correlate with cAMP levels: Rolipram, a PDe IV inhibitor, increased cAMP 6-fold, with minimal effects on the burst; whereas theophylline increased cAMP less than 2-fold but decreased the burst to less than half. Although theophylline and the adenylate cyclase activator, adenosine, inhibited fMLF-induced superoxide release, they did not inhibit production of inositol phosphates. Thus, these studies on inhibition of superoxide release implicated neither cAMP nor inositol phosphates.
Top-down regularization of deep belief networks (2013)

Designing a principled and effective algorithm for learning deep architectures is a challenging problem. The current approach involves two training phases: a fully unsupervised learning followed by a strongly discriminative optimization. We suggest a deep learning strategy that bridges the gap between the two phases, re-sulting in a three-phase learning procedure. We propose to implement the scheme using a method to regularize deep belief networks with top-down information. The network is constructed from building blocks of restricted Boltzmann machines learned by combining bottom-up and top-down sampled signals. A global op-timization procedure that merges samples from a forward bottom-up pass and a top-down pass is used. Experiments on the MNIST dataset show improvements over the existing algorithms for deep belief networks. Object recognition results on the Caltech-101 dataset also yield competitive results. 1
Effect of Reversible Intermittent Intra-abdominal Vagal Nerve Blockade on Morbid Obesity (2014)

clinicaltrials.gov Identifier: NCT01327976.
Power reduces the press of the situation: Implications for creativity, conformity, and dissonance. (2008)

Although power is often conceptualized as the capacity to influence others, the current research explores whether power psychologically protects people from influence. In contrast to classic social psychological research demonstrating the strength of the situation in directing attitudes, expressions, and intentions, 5 experiments (using experiential primes, semantic primes, and role manipulations of power) demonstrate that the powerful (a) generate creative ideas that are less influenced by salient examples, (b) express attitudes that conform less to the expressed opinions of others, (c) are more influenced by their own social value orientation relative to the reputation of a negotiating opponent, and (d) perceive greater choice in making counterattitudinal statements. This last experiment illustrates that power is not always psychologically liberating; it can create internal conflict, arousing dissonance, and thereby lead to attitude change. Across the experiments, high-power participants were immune to the typical press of situations, with intrapsychic processes having greater sway than situational or interpersonal ones on their creative and attitudinal expressions.
Incremental multiple-scan chain ordering for ECO flip-flop insertion (2013)

Testability of ECO logic is currently a significant bottleneck in the SOC implementation flow. Front-end designers sometimes require large functional ECOs close to scheduled tapeout dates or for later design revisions. To avoid loss of test coverage, ECO flip-flops must be added into existing scan chains with minimal increase to test time and minimal impact on existing routing and timing slack. We address a new Incremental Multiple-Scan Chain Ordering problem formulation to automate the tedious and time-consuming process of scan stitching for large functional ECOs. We present a heuristic with clustering, incremental clustering and ordering steps to minimize the maximum chain length (test time), routing congestion, and disturbance to existing scan chains. Test times for our incremental scan chain solutions are reduced by 5.3%, and incremental wirelength costs are reduced by 45.71%, compared to manually-solved industrial testcases.
Epigenetic Therapy: Histone Acetylation, DNA Methylation and Anti-Cancer Drug Discovery (2009)

Histone proteins are subject to a diverse range of post-translational modifications which, along with DNA methylation, play a major role in controlling gene expression, cell division, survival and differentiation. Alterations in these chromatin modifications are thought to contribute to important human diseases including cancer. Inhibition of the enzymes that introduce and remove these chromatin modifications is proving an effective approach to cancer therapy and inhibitors of histone deacetylases and DNA methyltransferases have been approved for use in haematological malignancies. Here we provide a background to the biology of chromatin modifications and review some of the evidence validating histone deacetylases and DNA methyltransferases as targets for anti-cancer drug discovery. We then focus on two of the key issues in this field; the identification of novel inhibitors to overcome shortcomings of first generation agents and the potential role of histone deacetylase and DNA methyltransferase inhibitors in combination therapies for oncology. Finally, we highlight some of the challenges that will need to addressed to further progress the development of epigenetic-based therapies for cancer.
A Nonlinear GaAs FET Model for Use in the Design of Output Circuits for Power Amplifiers (1985)

A nonlinear equivalent circuit model for the GaAs FET has been developed based upon the small-signal device model and separate current measurements, including drain-gate avalanche current data. The harmonic-balance technique is used to develop the FET RF load-pull characteristics in an amplifier configuration under large-signal operation. Computed and experimental load-pull results show good agreement.
Novel type of ZnO studied in combination with 1.5 eV a-SiGe:H pin diodes (2002)

Low gap 1.5 eV a-SiGe:H pin diodes with p-a-SiC:H windows (E/sub g/=1.95 eV) have been deposited on conventional SnO/sub x/ and novel Al-doped ZnO (ZnO:Al) to compare the influence of these TCOs (transparent conductive oxides) on diode parameters. Characterization by transmission, sheet resistance, and SEM photographs reveals comparable features for both types of TCOs, ZnO:Al additionally shows a very high chemical stability in hydrogen containing plasmas. Transmission and absorption experiments on the layer-system TCO/p-SiC:H (thin) indicate different rates of growth for p-a-SiC:H on ZnO:Al and SnO/sub x/, respectively.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Enumeration and Characterization of Iron(III)-ReducingMicrobial Communities from Acidic Subsurface Sediments ContaminatedwithUranium(VI) (2003)

Iron(III)-reducing bacteria have been demonstrated to rapidly catalyze the reduction and immobilization of uranium(VI) from contaminated subsurface sediments. Thus, these organisms may aid in the development of bioremediation strategies for uranium contamination, which is prevalent in acidic subsurface sediments at U.S. government facilities. Iron(III)-reducing enrichment cultures were initiated from pristine and contaminated (high in uranium, nitrate; low pH) subsurface sediments at pH 7 and pH 4 to 5. Enumeration of Fe(III)-reducing bacteria yielded cell counts of up to 240 cells ml(-1) for the contaminated and background sediments at both pHs with a range of different carbon sources (glycerol, acetate, lactate, and glucose). In enrichments where nitrate contamination was removed from the sediment by washing, MPN counts of Fe(III)-reducing bacteria increased substantially. Sediments of lower pH typically yielded lower counts of Fe(III)-reducing bacteria in lactate- and acetate-amended enrichments, but higher counts were observed when glucose was used as an electron donor in acidic enrichments. Phylogenetic analysis of 16S rRNA gene sequences extracted from the highest positive MPN dilutions revealed that the predominant members of Fe(III)-reducing consortia from background sediments were closely related to members of the Geobacteraceae family, whereas a recently characterized Fe(III) reducer (Anaeromyxobacter sp.) and organisms not previously shown to reduce Fe(III) (Paenibacillus and Brevibacillus spp.) predominated in the Fe(III)-reducing consortia of contaminated sediments. Analysis of enrichment cultures by terminal restriction fragment length polymorphism (T-RFLP) strongly supported the cloning and sequencing results. Dominant members of the Fe(III)-reducing consortia were observed to be stable over several enrichment culture transfers by T-RFLP in conjunction with measurements of Fe(III) reduction activity and carbon substrate utilization. Enrichment cultures from contaminated sites were also shown to rapidly reduce millimolar amounts of U(VI) in comparison to killed controls. With DNA extracted directly from subsurface sediments, quantitative analysis of 16S rRNA gene sequences with MPN-PCR indicated that Geobacteraceae sequences were more abundant in pristine compared to contaminated environments,whereas Anaeromyxobacter sequences were more abundant in contaminated sediments. Thus, results from a combination of cultivation-based and cultivation-independent approaches indicate that the abundance/community composition of Fe(III)-reducing consortia in subsurface sediments is dependent upon geochemical parameters (pH, nitrate concentration) and that microorganisms capable of producing spores (gram positive) or spore-like bodies (Anaeromyxobacter) were representative of acidic subsurface environments.