gebhart/patrepeval huggingface dataset:
Atomic Emission Spectrometry with Helium Plasmas for Liquid and Supercritical-Fluid Chromatography (1992)

Nonmetal excitation capabilities have provided the impetus for numerous studies of the analytical behavior of helium plasmas. Techniques involving gas chromatography and helium plasmas have matured; initial results coupling helium plasmas with supercritical fluid and liquid chromatography are promising. An overview of the mating of the nonmetal detection capabilities of helium plasmas with liquid and supercritical fluid chromatography is presented. Important considerations discussed include solvent-plasma interactions, interface design, and spectral behavior.
Chitosan Nanoparticles: A Promising System in Novel Drug Delivery (2010)

The ability of nanoparticles to manipulate the molecules and their structures has revolutionized the conventional drug delivery system. The chitosan nanoparticles, because of their biodegradability, biocompatibility, better stability, low toxicity, simple and mild preparation methods, offer a valuable tool to novel drug delivery systems in the present scenario. Besides ionotropic gelation method, other methods such as microemulsion method, emulsification solvent diffusion method, polyelectrolyte complex method, emulsification cross-linking method, complex coacervation method and solvent evaporation method are also in use. The chitosan nanoparticles have also been reported to have key applications in parentral drug delivery, per-oral administration of drugs, in non-viral gene delivery, in vaccine delivery, in ocular drug delivery, in electrodeposition, in brain targeting drug delivery, in stability improvement, in mucosal drug delivery in controlled drug delivery of drugs, in tissue engineering and in the effective delivery of insulin. The present review describes origin and properties of chitosan and its nanoparticles along with the different methods of its preparation and the various areas of novel drug delivery where it has got its application.
Substituted Carborane-Appended Water-Soluble Single-Wall Carbon Nanotubes:  New Approach to Boron Neutron Capture Therapy Drug Delivery (2005)

Substituted C(2)B(10) carborane cages have been successfully attached to the side walls of single-wall carbon nanotubes (SWCNTs) via nitrene cycloaddition. The decapitations of these C(2)B(10) carborane cages, with the appended SWCNTs intact, were accomplished by the reaction with sodium hydroxide in refluxing ethanol. During base reflux, the three-membered ring formed by the nitrene and SWCNT was opened to produce water-soluble SWCNTs in which the side walls are functionalized by both substituted nido-C(2)B(9) carborane units and ethoxide moieties. All new compounds are characterized by EA, SEM, TEM, UV, NMR, and IR spectra and chemical analyses. Selected tissue distribution studies on one of these nanotubes, {([Na(+)][1-Me-2-((CH(2))(4)NH-)-1,2-C(2)B(9)H(10)][OEt])(n)(SWCNT)} (Va), show that the boron atoms are concentrated more in tumors cells than in blood and other organs, making it an attractive nanovehicle for the delivery of boron to tumor cells for an effective boron neutron capture therapy in the treatment of cancer.
Demonstration of direct bonding between InP andgadolinium gallium garnet (Gd <sub>3</sub> Ga <sub>5</sub> O <sub>12</sub> ) substrates (1994)

The authors demonstrate the direct bonding of InP/Gd3Ga5O12 (GGG) and InP/GaInSb on GGG without glue. After chemical treatment, heat treatment was applied in an H2 atmosphere without a weight. This technique makes feasible the integration of semiconductor and magneto-optic devices.
Expanded Access to Naloxone Among Firefighters, Police Officers, and Emergency Medical Technicians in Massachusetts (2014)

Naloxone is a medication that reverses respiratory depression from opioid overdose if given in time. Paramedics routinely administer naloxone to opioid overdose victims in the prehospital setting, and many states are moving to increase access to the medication. Several jurisdictions have expanded naloxone administration authority to nonparamedic first responders, and others are considering that step. We report here on policy change in Massachusetts, where several communities have equipped emergency medical technicians, law enforcement officers, and firefighters with naloxone.
Collagenase Plaque Digestion for Facilitating Guide Wire Crossing in Chronic Total Occlusions (2003)

Local delivery of collagenase can safely facilitate guide wire crossing of CTO. This novel approach could lead to higher percutaneous coronary intervention success rates in CTO.
The use of radiotherapy for treatment of isolated locoregional recurrence of breast carcinoma after mastectomy (1986)

The role of radiotherapy in the treatment of isolated local recurrence of breast cancer after mastectomy is controversial. In an attempt to define this role, the results of moderate-dose radiotherapy in 90 such patients were reviewed. The median follow-up time for these patients was 81 months. The actuarial probability of local control after treatment was 42% at 5 years and 35% at 10 years. Freedom from distant failure was 30% at 5 years and only 7% at 10 years. The rate of appearance of distant metastasis was fairly constant at approximately 20% of patients per year. Overall survival was 50% at 5 years and 26% at 10 years. Overall survival and relapse-free survival were both chiefly influenced by the disease-free interval (DFI). Patients who presented with a DFI of greater than or equal to 2 years had a 5-year actuarial overall survival rate of 58% compared to 33% for patients with a DFI of less than 2 years (P = 0.04). Subsequent local failures after radiotherapy were principally seen at the initial site of recurrence, but also at other sites in or at the edge of the radiation fields. These results strongly suggest that patients with apparently isolated local recurrence after mastectomy are incurable by further local treatment. Effective systemic therapy is required to improve the results in these patients. Radiotherapy is a useful palliative procedure in patients with long disease-free intervals. The role of radiotherapy in conjunction with systemic therapy is, as yet, undefined.
Towards odyssey-VCS 2 (2008)

Models are becoming first class artifacts in Software Engineering. Due to that, an infrastructure is needed to support model evolution in the same way we have for source-code. One of the key elements of such infrastructure is a version control system properly designed for models. In previous work, we presented Odyssey-VCS, a version control system tailored to fine-grained UML model elements. In this paper, we discuss the main improvements that we are incorporating on the second release of this system, which are: support for UML 2, reflective processing, explicit branching and auto-branching, generic merge algorithm, support for pessimistic concurrency policy, and support for hooks.
Comparison of five one-step reconstruction algorithms for spectral CT (2018)

Over the last decade, dual-energy CT scanners have gone from prototypes to clinically available machines, and spectral photon counting CT scanners are following. They require a specific reconstruction process, consisting of two steps: material decomposition and tomographic reconstruction. Image-based methods perform reconstruction, then decomposition, while projection-based methods perform decomposition first, and then reconstruction. As an alternative, 'one-step inversion' methods have been proposed, which perform decomposition and reconstruction simultaneously. Unfortunately, one-step methods are typically slower than their two-step counterparts, and in most CT applications, reconstruction time is critical. This paper therefore proposes to compare the convergence speeds of five one-step algorithms. We adapted all these algorithms to solve the same problem: spectral photon-counting CT reconstruction from five energy bins, using a three materials decomposition basis and spatial regularization. The paper compares a Bayesian method which uses non-linear conjugate gradient for minimization (Cai et al 2013 Med. Phys. 40 111916-31), three methods based on quadratic surrogates (Long and Fessler 2014 IEEE Trans. Med. Imaging 33 1614-26, Weidinger et al 2016 Int. J. Biomed. Imaging 2016 1-15, Mechlem et al 2018 IEEE Trans. Med. Imaging 37 68-80), and a primal-dual method based on MOCCA, a modified Chambolle-Pock algorithm (Barber et al 2016 Phys. Med. Biol. 61 3784). Some of these methods have been accelerated by using μ-preconditioning, i.e. by performing all internal computations not with the actual materials the object is made of, but with carefully chosen linear combinations of those. In this paper, we also evaluated the impact of three different μ-preconditioners on convergence speed. Our experiments on simulated data revealed vast differences in the number of iterations required to reach a common image quality objective: Mechlem et al (2018 IEEE Trans. Med. Imaging 37 68-80) needed ten iterations, Cai et al (2013 Med. Phys. 40 111916-31), Long and Fessler (2014 IEEE Trans. Med. Imaging 33 1614-26) and Weidinger et al (2016 Int. J. Biomed. Imaging 2016 1-15) several hundreds, and Barber et al (2016 Phys. Med. Biol. 61 3784) several thousands. We also sum up other practical aspects, like memory footprint and the need to tune extra parameters.
Elliptical and Circular Current Sheets to Produce a Prescribed Internal Field (1967)

Any desired two-dimensional magnetic field, which is compatible with Maxwell's equations in empty space, can be produced inside a given elliptic or circular cylinder by a distribution of currents flowing along the elements of the cylinder. Formulas are given for the required current distribution, the resulting external field, and for the total field energy in the internal and external regions. It is further possible to eliminate the external or stray field completely while producing the prescribed inner field by adding a second confocal elliptic (or coaxial circular) current sheet. Formulas are given for the required current distributions. To facilitate their use the formulas are here presented unencumbered by derivations but in a form which makes the correspondence between the elliptic and circular cases, as well as the specialization to median plane fields, appear as simply as possible.
Continuous 3D environment sensing for autonomous robot navigation and mapping. (2007)

S.39-42
Effect of h-EGF and h-EGF 1-48 on histamine-stimulated gastric acid secretion in rats and monkeys. (1993)

The effect of human epidermal growth factor (h-EGF) and its derivative human epidermal growth factor 1-48 (h-EGF 1-48) on histamine-stimulated gastric acid secretion was studied in monkeys and rats. In monkeys, both h-EGF and h-EGF 1-48 given intravenously (i.v.) in a stepwise manner and in doses ranging from 0.01 to 10 nmol/kg, gradually suppressed gastric acid secretion. At the highest dose tested, both compounds essentially abolished gastric acid output. In the same animals, i.v. administration of 1 nmol/kg of h-EGF or h-EGF 1-48 caused an inhibition of gastric acid output that reached a peak at 90 and 60 min after the administration of h-EGF or h-EGF 1-48 respectively. After this maximum gastric inhibitory effect, a gradual return toward pre-injection values was observed. In rats, after subcutaneous (sc) administration, both h-EGF and h-EGF 1-48 dose-dependently inhibited histamine-stimulated gastric acid output as measured 60 min after the administration of the compounds. The maximum inhibitory activity on gastric acid output, observed at a dose of 100 nmol/kg, was 74.4% and 76.0% for h-EGF and h-EGF 1-48 respectively. The same dose of both compounds, however, failed to significantly inhibit gastric acid secretion when administered orally. In all the studies h-EGF 1-48 showed activity and potency comparable to h-EGF.(ABSTRACT TRUNCATED AT 250 WORDS)
Cerebrospinal Fluid β-Amyloid 42 and Tau Proteins as Biomarkers of Alzheimer-Type Pathologic Changes in the Brain (2009)

Cerebrospinal fluid Abeta42 and tau proteins are biomarkers of AD-associated pathologic changes in the brain. The combination of abnormally low CSF Abeta42 level and abnormally high CSF tau level predicted the presence of AD pathologic features with high accuracy. This combination assay may be helpful in diagnosing the presence of AD pathologic changes in the brain.
Development of Parametric Mesh Morphing Technique (2008)

We developed the parametric mesh morphing technique, which can be used to change the shape of existing analytical mesh models, and generate a mesh model for a new shape by morphing the mesh model for the previous one. Therefore, our method is suitable to use for analysis during the early stage of design because it reduces the amount of time required to generate analytical mesh models. Compared with conventional methods, our method preserves the geometric features of the original mesh in the morphed mesh because of geometric feature identification and parametric mesh morphing. Geometric feature identification technique can classify outside surface of mesh as plane, quadric (cylinder, cone and sphere) and free-surface. Shape of mesh can be transformed in maintaining the identified geometry feature by using developed parametric mesh morphing technique. We demonstrated the effectiveness of our method by applying it to models of a bracket and a connection rod.
Early Diagnosis of Hypopharyngeal and Cervical Esophageal Cancer (1987)

We retrospective reviewed 139 previously untreated patients with carcinoma of the hypopharynx and carvical esophagus who were seen between 1965 and 1984. The clinical stage was closely related to the prognosis. The prognosis of the hypopharyngeal and cervical esophageal cancer was poor, mainly because the patients who visited us already had advanced diseases. Therefore, we examined the initial sign and final diagnosis of these patients. For earlier diagnosis, screening of the high risk group complaining of throat discomfort should be routinely performed.
A CA Repeat Polymorphism of the IFN- <i>gamma</i> Gene Is Associated with Susceptibility to Type 1 Diabetes (2000)

Recent studies have shown that loci outside the HLA region are involved in determining susceptibility to type 1 diabetes. Polymorphisms in the coding and noncoding regions of the genes encoding cytokines may be involved in modulating the immune response to self and nonself antigens. There is increasing evidence that an imbalance and disruption of the Th1 and Th2 T cell subsets play a key role in the development of experimental and clinical type 1 diabetes. The aim of this study was to investigate the frequency of a CA dinucleotide repeat polymorphism in the interferon-gamma (IFN-gamma) gene (IFNG) and a C(-590)T polymorphism of the interleukin-4 (IL-4) gene in 236 Caucasoid patients with type 1 diabetes. There was a highly significant increase in the 3/3 IFNG genotype in the patients compared with normal healthy controls (34.3% vs. 13.5%, p< 0.0001) as well as a significant increase in allele 3 of the IFNG locus in the patients compared with controls (51.9% vs. 31.7%, p< 0.00001). In contrast, no significant differences were found in the frequency of the C(-590)T IL-4 polymorphism between patients and controls. These results suggest that polymorphisms of the IFNG gene may modify the function of this proinflammatory mediator and the response to pancreatic islet beta cells.
Wavelength Bistability and Switching in Two-Section Quantum-Dot Diode Lasers (2010)

We report lasing wavelength bistability with respect to applied bias on the saturable absorbers in two-section mode-locked quantum dot lasers. We show data from three different devices exhibiting wavelength bistability. All lasers display wavelength bistability. Only one lasing wavelength is present at a time, with all other wavelengths totally quenched. The switchable ranges (the wavelength difference between two bistable lasing branches) are different for all three lasers and in one device can be manipulated by changing the current injection. All lasers show the remarkable property of switching only in integer multiples of about 8 nm. The bistable operation can be explained by the interplay of the cross-saturation and self-saturation properties in gain and absorber, and the quantum-confined Stark effect in absorber. The measured switching time between bistable wavelengths is 150 ps.
Femtosecond laser microsurgery system controlled by optical coherence tomography (2008)

Due to nonlinear interaction with optical transparent and scattering samples the femtosecond technology is a very useful tool for high precision micro surgery on biological tissues. At the same time femtosecond lasers are ideal light sources for imaging methods such as optical coherence tomography (OCT) due to the broad spectrum of the laser, which is necessary for creating ultra short pulses. Using OCT structures within biological tissues can be imaged non invasive with a resolution within the low m-range. The combined use of an ultra short pulse laser for cutting of biological tissues as well as imaging via OCT is a very interesting tool. It opens up a wide range of new surgery techniques and improves many existing methods due to high precision and high flexibility of the cutting process. Therefore we combined a femtosecond cutting system and a fourier domain OCT. In this attempt the OCT is operated with an SLD and is used alternately to the cutting system. The OCT is integrated into the optical path which enables in situ imaging of the surgery area before and after treatment.
Fast-scan voltammetry of biogenic amines (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFast-scan voltammetry of biogenic aminesJohn E. Baur, Eric W. Kristensen, Leslie J. May, Donna J. Wiedemann, and R. Mark. WightmanCite this: Anal. Chem. 1988, 60, 13, 1268–1272Publication Date (Print):July 1, 1988Publication History Published online1 May 2002Published inissue 1 July 1988https://pubs.acs.org/doi/10.1021/ac00164a006https://doi.org/10.1021/ac00164a006research-articleACS PublicationsRequest reuse permissionsArticle Views1360Altmetric-Citations229LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Therapeutic Relationship (1991)

The relationship established between the occupational therapist and the patient is a key element in facilitating therapy. This article examines the nature of the therapeutic relationship and discusses the various issues that need to be considered when estabilshing this relationship.
An affordable millimeter-wave beam-steerable antenna using interleaved planar subarrays (2003)

Design and fabrication aspects of an affordable planar beam steerable antenna array with a simple architecture are considered in this paper. Grouping the elements of a phased array into a number of partially overlapped subarrays and using a single phase shifter for each subarray, generally results in a considerable reduction in array size and manufacturing costs. However, overlapped subarrays require complicated corporate feed networks and array architectures that cannot be easily implemented using planar technologies. In this paper a novel feed network and array architecture for implementing a planar phased array of microstrip antennas is presented that enables the fabrication of low-sidelobe, compact, beam-steerable millimeter-wave arrays and facilitates integration of the RF front-end electronics with the antenna structure. This design uses a combination of series and parallel feeding schemes to achieve the desired array coefficients. The proposed approach is used to design a three-state switched-beam phased array with a scanning width of /spl plusmn/10/spl deg/. This phased array which is composed of 80 microstrip elements, achieves a gain of >20 dB, a sidelobe level of <-19 dB and a 10-dB bandwidth of >6.3% for all states of the beam. The antenna efficiency is measured at 33-36% in X band. It is shown that the proposed feeding scheme is insensitive to the mutual coupling among the elements.
Hepatitis B virus (HBV) infections in turtles (1989)

Thirty turtles (15 Clemys mutica and 15 Geoclemys reevesii) which were inoculated with human sera those were positive for hepatitis B surface antigen (HBsAg) and hepatitis B "e" antigen (HBeAg) were found to be infected with hepatitis B virus (HBV). The levels of HBV infection markers, such as HBsAg and antibody to HBsAg (anti-HBsAg), were retinely monitored in the turtles' serum for 46 weeks. Within two weeks of the inoculation, 42% of the turtles tested were positive for HBsAg, and their reciprocal titers as measured by reverse passive hemagglutination (RPHA) and enzyme linked immunoabsorbance assay (ELISA) ranged from 16 to 96. Within 20 weeks, the remaining turtles tested HBsAg positive, as confirmed by ELISA. At 20 weeks, all but one of the turtles exhibited changes in HBV blood marker from HBsAg to anti-HBs; the one exception was positive for both HBsAg and anti-HBs. At the 47th week, 7 animals were killed and their organs were examined for HBV infected cells utilizing an immunofluorescent technique. Numerous fluorescent cells which reacted with human anti-HBs nad anti-HBc were observed in the following organs: pancreas, liver, kidney, and brain. Histopathologically, edematous changes in hepatocytes and minor cellular infiltration attributed to an inflammatory response were noted. Liver and kidney cells from the infected animals were cultured, and HBV antigen positive cells for HBsAg and HBcAg were detected in the cultures. Throughout the experiment, HBsAg was detected in the supernatant by ELISA. Virus particles which were indistinguishable from Dane particles were seen in the cytoplasmic vacuoles of the cultured cells by electron microscopy. Finally, the presence of HBV DNA was established by molecular hybridization techniques in the culture supernatants of kidney cells from the infected turtles.
Interferon Effects on Friend Leukaemia Cells. I. Expression of Virus and Erythroid Markers in Untreated and Dimethyl Sulphoxide-treated Cells (1980)

The effects of low doses (40 to 1000 units/ml) of mouse interferon (IF) on the expression of Friend leukaemia virus (FLV) and globin genes in Friend leukaemia cells (FLC) have been examined. IF blocks production of extracellular virus, but virus antigens accumulate in the cytoplasm. In cells treated with IF at the time of seeding, there is a reduction in the amount of RNA specified by the lymphatic leukaemia virus (LLV) component of FLV; with the same IF dose there is a small but definite stimulation of haemoglobin and globin mRNA synthesis. The effects of IF on LLV gene expression are even more pronounced in dimethyl sulphoxide (DMSO)-stimulated LFC. No correlation was found between LLV gene expression and the appearance of erythroid markers.