gebhart/patrepeval huggingface dataset:
Interferon induction by Lactobacillus bulgaricus and Streptococcus thermophilus in mice. (1992)

This study investigates the effect of intraperitoneal injection of L. bulgaricus and S. thermophilus on interferon production by Swiss mice. The serum from mice given 5 x 10(7) L. bulgaricus in 0.5 ml saline showed a maximal production of 300 U/ml of alpha/beta interferon activity six hours after injection. Cellular integrity appears to be necessary for stimulation; heat-treated bacteria had little effect, while irradiated-bacteria had a greater effect. TNF was also produced, the sera of mice with high IFN also contained 300 U/ml TNF. Streptococcus thermophilus produced no detectable increase in serum IFN, but the 2'-5' A synthetase activity of peritoneal cells was elevated suggesting that small amounts of interferon were produced. Injection of Streptococcus thermophilus plus Lactobacillus bulgaricus did not change the serum interferon response to L. bulgaricus. These observations suggest that non-pathogenic bacteria such as those used in food processing, can stimulate IFN production in mice. There is some evidence that the bacterial cell walls might be responsible for at least part of this effect.
Tensile Strength of Fiber-Reinforced Composites: III. Beyond the Traditional Weibull Model for Fiber Strengths (2000)

Commercially available graphite and ceramic fibers exhibit statistical strength distributions having separate Weibull moduli p' for the scaling of strength versus fiber length and p for the distribution of strengths across a collection of fibers at fixed length. It is shown that very similar distributions arise if each fiber in a collection of fibers exhibits Weibull length scaling according to p' but with the scale strength appropriate to each fiber distributed according to a Weibull modulus m, with the relationship [ILLEGIBLE]. An analytic model based on the Global Load Sharing approximation is used to predict the trends in composite tensile strength for composites composed of such fibers. From this insight, an analytic model for the strength of composites containing such fibers, but with Local Load Sharing (LLS), is developed by adapting a previous model. Numerical simulations of the tensile strength under LLS are then presented and excellent agreement in the composite strength distribution between the numerical and analytic models is demonstrated. The new analytic model is applied to predict the tensile strength of several unidirectional graphite/epoxy composites, and the predictions shown agree well with experimental strengths. The differences between theory and experiment approach the order of the uncertainties in underlying fiber strengths and fiber volume fractions in the composites.
Antihuman epidermal growth factor receptor 2 antibody herceptin inhibits autocrine motility factor (AMF) expression and potentiates antitumor effects of AMF inhibitors. (2002)

Overexpression of the human epidermal growth factor receptor (HER) 2 has been linked to the development and maintenance of malignant phenotypes in breast tumors. In addition, the growth and dissemination of human cancers are regulated in part by the autocrine motility factor (AMF)/phosphoglucose isomerase shown to be up-regulated by heregulin (HRG) in breast cancer cells. This study was undertaken to explore the effect of anti-HER2 monoclonal antibody 4D5 [Herceptin (HCT)] on AMF expression and the potential of its augmentation by specific simple sugar AMF inhibitors. Here we show that HCT treatment of high HER2-expressing breast cancer SK-BR3, BT-474, and ZR-75R cells resulted in down-regulation of AMF mRNA and protein. HCT inhibited the ability of HRG to induce AMF expression in cells with a normal HER2 level, and HCT-mediated down-regulation could be reversed by HRG treatment in breast cancer cells with a high HER2 level. HCT also inhibited transcription from a chimeric pGL3-Luc vector-based reporter system containing the 1.8-kb promoter region of human AMF. Treatment of breast cancer cells with the combination of HCT and specific AMF inhibitors, erythrose 4-phosphate or D-mannose 6-phosphate, resulted in an additive inhibitory effect on both the growth rate and invasiveness of cells as compared with treatment with each agent alone. Results presented here suggest that HCT can effectively block both ligand-induced and constitutive expression of AMF associated with high HER2 overexpression, implying a role of the AMF pathway in the action of HCT. Accordingly, the combination of AMF inhibitor with HCT can potentiate the growth-inhibitory and anti-invasive action of HCT in breast cancer cells.
K-isomorphism (2010)

Serious concerns on privacy protection in social networks have been raised in recent years; however, research in this area is still in its infancy. The problem is challenging due to the diversity and complexity of graph data, on which an adversary can use many types of background knowledge to conduct an attack. One popular type of attacks as studied by pioneer work [2] is the use of embedding subgraphs. We follow this line of work and identify two realistic targets of attacks, namely, NodeInfo and LinkInfo. Our investigations show that k-isomorphism, or anonymization by forming k pairwise isomorphic subgraphs, is both sufficient and necessary for the protection. The problem is shown to be NP-hard. We devise a number of techniques to enhance the anonymization efficiency while retaining the data utility. A compound vertex ID mechanism is also introduced for privacy preservation over multiple data releases. The satisfactory performance on a number of real datasets, including HEP-Th, EUemail and LiveJournal, illustrates that the high symmetry of social networks is very helpful in mitigating the difficulty of the problem.
Highly Potential Antiplasmodial Restricted Peptides (2014)

Malaria is an infectious disease responsible for approximately one million deaths annually. The antimalarial effects of angiotensin II and its analogs against Plasmodium gallinaceum and P. falciparum have recently been reported. To evaluate antiplasmodial activity, we synthesized five angiotensin II-restricted analogs containing disulfide bridges. To accomplish this, peptides containing two inserted amino acid residues (cysteine) were synthesized by the Fmoc solid-phase method, purified by liquid chromatography, and characterized by mass spectrometry. Conformational studies were performed by circular dichroism. The results indicated that two of the analogs had higher antiplasmodium activity (92% and 98% activity) than angiotensin II (88% activity), measured by fluorescence microscopy. Results showed that the insertion position must be selected, to preserve the hydrophobic interactions between the non-polar residues, as this affects antiplasmodial activity. The circular dichroism studies suggested that the active analogs as well as the native angiotensin II adopt a β-turn conformation in different solutions. This approach provided insight for understanding the effects of restricting the ring size and position on the bioactivity of angiotensin II and provides a new direction for the design of potential chemotherapeutic agents.
Hierarchical Join/Prune Attributes (2016)

This document defines a hierarchical method of encoding Join/Prune
attributes that provides a more efficient encoding when the same
attribute values need to be specified for multiple sources in a PIM
Join/Prune message. This document updates RFC 5384 by renaming the
encoding type registry specified there.
Preliminary data on the involvement of B, C and D hepatitis viruses in the etiopathogenesis of chronic lymphoproliferative syndromes in Romania. (2009)

We ascertained an almost equally represented prevalence of HCV and HBV infection in patients with CL. The levels of HBV, HCV and HDV viremia were low in most of the cases. The most frequent form of CL was B cell NHL. We found an equal distribution between indolent and aggressive forms of NHL associated to hepatitis virus infection.
Unified Direct-Flux Vector Control for AC Motor Drives (2011)

This paper introduces a unified direct-flux vector control scheme that is suitable for sinusoidal ac motor drives. The ac drives considered here are induction motor, synchronous reluctance, and synchronous permanent-magnet (PM) motor drives, including interior and surface-mounted PM types. The proposed controller operates in stator flux coordinates: The stator flux amplitude is directly controlled by the direct voltage component, while the torque is controlled by regulating the quadrature current component. The unified direct-flux control is particularly convenient when flux weakening is required since it easily guarantees maximum torque production under current and voltage limitations. The hardware for control is standard, and the control firmware is the same for all the motors under test with the only exception of the magnetic model used for flux estimation at low speed. Experimental results on four different drives are provided, showing the validity of the proposed unified control approach.
Reduced L- and M- and increased S-cone functions in an infant with thyroid hormone resistance due to mutations in the<i>THRβ2</i>gene (2012)

We document a congenital disorder of cone function characterized by severely reduced L- and M-cone responses and increased S-cone responses caused by deleterious mutations in the THRβ2 gene in thyroid resistant patients. Thyroid hormone, via TRβ2, is critical for determining cone-type differentiation in humans.
In vivo Imaging with Stimulated Raman Scattering Microscopy (2011)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text C.W. Freudiger and X.S. Xie, "In vivo Imaging with Stimulated Raman Scattering Microscopy," Optics & Photonics News 22(12), 27-27 (2011) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Interpretation of Seabed Geomorphology Based on Spatial Analysis of High-Density Airborne Laser Bathymetry (2005)

Airborne laser bathymetric (ALB) systems rapidly acquire large, high-quality datasets via variable swath widths that are independent of water depth. Laser bathymetric survey tools have applicability in clear coastal (Case II) waters down to −70 meters depth. Deployed along the southeast Florida (Palm Beach, Broward, and Miami-Dade Counties) coast, an advanced ALB system provided a continuous dataset for 160 kilometers of coast from onshore to 6 kilometers offshore. Digital terrain models developed from this high-density bathymetric data permitted recognition of numerous seafloor features and bathymetric patterns from different image formats. Bathymetric analysis of the 600-km2 survey area on the narrow continental shelf shows inherited lithologic features that are partly covered by surficial sediments. Primary parabathic provinces include: (1) nearshore rocky zones dominated by the Anastasia Formation, (2) coral-algal reef systems (Florida Reef Tract [FRT]), and (3) marine terraces. Secondary sedimentary subprovinces include shoreface sands, inter-reefal sedimentary infills (coral rubble in basal sequences and near reef gaps), and finer-grained materials seaward of the FRT. Tertiary topographic features include: (1) longshore bar and trough systems, shoals, sand sheets, and diabathic channels; (2) reef crests and ledges, forereef spurs and grooves, sediment ramps in large reef gaps, and incised paleo-river channels; and (3) drowned karst topography. Hierarchical organization of these bathymetric features is now possible for the first time because of the increased accuracy and density of bathymetric data obtained by ALB systems.
ChemInform Abstract: Synthesis of 4‐Azepanones and Heteroaromatic‐Fused Azepines. (2012)

Abstract Two independent routes to the intermediate heterocycles (VII) and (VIII) are investigated.
An optical clock distribution network for gigascale integration (2002)

A novel system-level model describing a printed wiring board-level, high-fanout, curved aperture optical waveguide H-tree network using volume grating focusing couplers is presented. The intra-chip optical network globally distributes an optical signal to monolithic CMOS receivers for local clock distribution. An estimation for the available optical output power as a function of distribution fanout is presented. Assuming -2 dB optical loss per y-junction, a distribution fanout of 256 can be achieved for an optical input power of 1.23 W.
Embedded Ethernet and Internet Complete (2003)

From the Publisher:
Bringing together two areas of computer technology-networking and embedded systems-this developer's guide offers guidance and examples for each of these, with a focus on the special requirements and limits of embedded systems. Because developing an embedded system for networking requires knowledge from many areas, including circuit design, programming, network architecture, and Ethernet and Internet protocols, developers are given valuable technical information on each that can be put to use right away. Covered are the advantages and limits of using Ethernet to connect embedded systems in a local network, hardware and program code needed to connect an embedded system to an Ethernet network and the Internet, and how to build a network. Also discussed are how embedded systems can use TCP/IP and related protocols and how personal-computer applications can use the protocols to communicate with embedded systems. Developers will learn how their Web server's pages can include dynamic, real-time content and respond to user input.
Author Biography: Jan Axelson has written dozens of articles for technical publications including Embedded Systems Programming, EDN, and Circuit Cellar. She is the author of USB Complete, Serial Port Complete, and Parallel Port Complete. She lives in Madison, Wisconsin.
Evaluation of Nanostructured Sorbents in Differential Bed Reactors for Elemental Mercury Capture (2008)

Elemental mercury (Hg0 ) capture by heterogeneous gas–solid reaction with nanostructured sorbents was studied in a differential bed reactor system at room temperature. Commercially available (four types of iron oxide, titanium dioxide, titania pillared clay) and in-house synthesized (magnetite and SUZ-4 zeolite) sorbents were studied. Elemental mercury capture efficiency greater than 70% was observed for TiO2, TiO2 pillared clay (PILC), SUZ-4 zeolite, and one of the commercial iron oxides on irradiation with UV light for an inlet mercury concentration of 75 ± 1.9 μg/m3. The initial rate of Hg0 capture per unit mass of sorbent was highest for TiO2. The initial capture rates, rinit = kS0 (1-x)CαHg,0, were determined with α values of 1.03, 1.21, 1.19, and 1.51 for TiO2, TiO2 PILC, SUZ-4 zeolite, and one of the commercial iron oxides, respectively. In addition, the rate constants (k) were found to be 2.43×10−17, 4.66×10−19, 3.41×10−20 and 8.6×10−20μg1-α m3α-2 s−1 for TiO2, TiO2 PILC, SUZ-4 zeolite, and one of the commercial iron oxides, respectively. A three-step sequential extraction technique, targeting surface bound, acid-soluble, and encapsulated mercury species, was used to investigate the binding mechanisms and the mobility of mercury. The mercury associated with one of the commercial iron oxides was more labile than the mercury associated with the other sorbents. Titania (TiO2) shows the greatest potential to be used as a sorbent to capture elemental mercury on irradiation with UV light based on the results of this study.
A 6‐Month Multi‐Center Evaluation of Adjunctive Tetracycline Fiber Therapy Used in Conjunction With Scaling and Root Planing in Maintenance Patients: Clinical Results (1994)

The purpose of this study was to compare the efficacy of scaling and root planing (S and RP) alone versus tetracycline fiber therapy used adjunctively with S and RP in the treatment of localized recurrent periodontitis sites in maintenance patients. A total of 113 patients receiving regular supportive periodontal therapy (SPT) were treated with whole mouth S and RP. Two non-adjacent sites in separate quadrants were selected in each patient for monitoring based on criteria that the sites were 5 to 8 mm deep and had a history of bleeding on probing. The chosen sites were randomly assigned to one of the two treatment groups. Probing depth (PD), bleeding on probing (BOP), and clinical attachment level (CAL) were measured at baseline and 1, 3, and 6 months. At 1, 3 and 6 months, adjunctive fiber therapy was significantly better in reducing PD (P < 0.05) and reducing BOP (P < 0.05) than S and RP alone. At 6 months, fiber therapy was significantly better in promoting clinical attachment gain (P < 0.05) than S and RP alone. Overall, these results indicate that fiber therapy significantly enhanced the effectiveness of S and RP in the management of localized recurrent periodontitis sites, in patients receiving regular supportive periodontal treatment.
A natriuretic principle derived from kidney tissue of volume-expanded rats (1975)

Homogenates of kidneys from hydropenic and volume-expanded rats were subjected to gel filtration with Sephadex G-25. A fraction of the eluate coincident with the fourth UV peak was injected into the aorta of rats with one kidney excluded. A fraction eluting before the albumin peak was utilized as a control. Significant natriuresis and diuresis were observed after infusion of the fraction obtained from volume-expanded kidneys but not after infusion of the fraction from hydropenic kidneys or the control fraction. The natriuresis occurred in in the absence of changes in mean blood pressure, hematocrit, plasma sodium and potassium, glomerular filtration rate, and potassium excretion. The response was apparent immediately after infusion and persisted for up to 150 min. These results verify the existence of a low molecular weight natriuretic substance which may be preferentially bound to the kidney after its volume-stimulated release into the circulation.
Studies on the specificity of rabbit hepatic carbohydrate-binding protein using neoglycoproteins (1980)

The binding of amidinoneoglycoproteins of bovine serum albumin to rabbit liver membranes was measured. Derivatives of bovine serum albumin to which equivalent amounts of beta-D-Gal, 6-O-Me-beta-D-Gal, beta-D-Fuc, alpha-L-Ara, beta-D-Glc, beta-D-Xyl, and beta-D-GalNAc had been attached bound to the membranes equally well. The attachment of alpha-D-Man, beta-L-Fuc, beta-D-GlcNAc, beta-D-allose, 3-O-Me-beta-D-Glc, and 2-deoxy-beta-D-Glc did not promote strong binding. The specificity of binding to the membranes was confirmed by measuring the binding of neoglycoproteins to the purified rabbit hepatic carbohydrate-binding protein immobilized on Sepharose 4B. The results indicate that, for binding, (1) neither the 6-OH (D-Fuc) nor the 5-CH2OH (L-Ara; D-Xyl) is required, (2) the 4-OH can be axial (D-Gal; L-Ara) or equatorial (D-Glc; D-Xyl), (3) the 3-OH must be equatorial (D-Glc) not axial (D-All) nor may it be substituted (3-O-Me-D-Glc), (4) the 2-OH must be equatorial (D-Glc) not axial (D-Man) and must be present (2-deoxy-D-Glc), and (5) the 2-OH can be replaced by an equatorial acetamido group if the 4-OH is axial (D-GalNAc) but not if it is equatorial (D-GlcNAc).
Current status of infrared fiber optics for medical laser power delivery (1993)

There are a host of fiber-optic delivery devices available for use with the Er:YAG, HF, CO, and CO2 lasers at 2.9, 2.8, 5.3, and 10.6 microns wavelengths, respectively. While many of these fibers are not as convenient to use as conventional silica fibers, they offer the ability to deliver infrared laser energy for a wide variety of medical applications. The fundamental attributes of fluoride glass, chalcogenide glass, single-crystal sapphire, and polycrystalline silver halide optical fibers are reviewed and their practical properties tabulated.
Crosslinked styrene‐maleic acid copolymer complexes of some transition metals and their adsorption behavior (2005)

Abstract Transition metal complexes of linear and crosslinked styrene‐maleic acid copolymer were prepared in ethyl alcohol. The complexes appear as micro clusters fairly uniformly distributed in the copolymer matrix. Vapor adsorption–desorption studies of the complex beads with methyl isobutyl ketone (MIBK), toluene and ethyl alcohol show initial fast release followed by a steady and slow release. Hydrogen adsorption at room temperature was studied for a few complexes up to about 650 torr, which showed initial slow adsorption followed by a rapid increase at about 550 torr. Copyright © 2005 John Wiley & Sons, Ltd.
SLEEP INDUCED BY SUBTHALAMIC LESIONS WITH THE HYPOTHALAMUS INTACT (1940)

The sleep-producing effect of hypothalamic lesions has been convincingly demonstrated (Ranson1). There are, however, still many unsolved problems which bear upon the central mechanism of the sleep-waking process. Supporting the view, notably that of Kleit-man,2 that sleep primarily depends upon a reduction of afferent impulses, Bremer3 demonstrated that a transection of the brain stem behind the 3rd nuclei produces in the electrocorticogram and in the behavior of the eyeballs signs characteristic of sleep. Extensive bilateral thalamic lesions which destroyed the chief endings of the centripetal pathways from the spinal cord and rhombencephalon (Ranson) failed, however, to abolish the normal waking state. This indicates that centripetal systems outside the dorsal thalamus play an important part in maintaining the waking state. Thalamic lesions extending more ventrally than those of Ranson, reaching beyond the dorsal thalamus, but remaining outside the hypothalamus, were produced by Spiegel and Inaba,4 who ...
Reading Texts, Reading Traditions: African Masks and American Law (2000)

My subject in this Essay is the relation between a text or other artifact and the tradition against which it acts. I want to begin by borrowing from a book that seems to me to represent a model-not the only model, of course, but a very good one-of a certain kind of cultural investigation. The book is Inventing Masks by Z.S. Strother, an art historian at Columbia University who specializes in African art. Its material subject is a set of face masks made by the Central Pende, an African people in what is now the Democratic Republic of Congo.
Computational modeling and emerging trend in agriculture (2015)

Computational modelling with the use of intelligence techniques for computing the agricultural output by providing minimum input data to lessen the time through cutting down the multi locational field trials and also the labours and other inputs is getting momentum. Development of locally suitable integrated farming systems (IFS) is the utmost need of the day, particularly in India where about 95% farms are under small and marginal holding size. The computational models are developed through incorporation of all independent variables which affect directly or indirectly the output of a system. Models can also be useful in teaching processes involved in the systems and its behaviour in response input variables. Calibration, verification, and validation are very important procedure to produce accurate simulation models. Computer simulations are good at portraying and comparing theoretical scenarios, but in order to accurately model actual case studies they have to match what is actually happening today. It is the research tools which can be used to curtail the huge expenditure in conducting the multiple experiments either in the field or laboratory. Computational modelling is increasingly effective for designing and analysis of the system. This is very important tool to analyses the effect of different scenarios on the systems and its interaction among themselves.