gebhart/patrepeval huggingface dataset:
High-frequency application of MOS compact models and their development for scalable RF model libraries (2002)

The evaluation of MOS compact models, focusing on BSIM3v3, is performed with specific development described toward scalable RF libraries suitable for high-frequency mixed-signal circuit design. Additional parasitic elements are added to the compact model to better describe its operation at higher frequency. This extrinsic subcircuit includes the gate resistance and complex substrate admittance which are scalable and physically based, and a detailed parameter extraction procedure for each is described. Small-signal y-parameters and noise behavior of the extended model are used to verify the match to high-frequency on-wafer measurements.
Reassurance (1955)

ConclusionDiphtheria is a rare disease at the moment, but positive laboratory reports are still common.Treatment depends primarily on the signs and symptoms, and no laboratory report should create a clinical emergency.The fever hospital clinician or the medical officer of health should be consulted when swabs are reported positive.Patients should not be rushed into hospital because something has grown in a laboratory.
"Like Having a Really Bad PA" (2016)

The past four years have seen the rise of conversational agents (CAs) in everyday life. Apple, Microsoft, Amazon, Google and Facebook have all embedded proprietary CAs within their software and, increasingly, conversation is becoming a key mode of human-computer interaction. Whilst we have long been familiar with the notion of computers that speak, the investigative concern within HCI has been upon multimodality rather than dialogue alone, and there is no sense of how such interfaces are used in everyday life. This paper reports the findings of interviews with 14 users of CAs in an effort to understand the current interactional factors affecting everyday use. We find user expectations dramatically out of step with the operation of the systems, particularly in terms of known machine intelligence, system capability and goals. Using Norman's 'gulfs of execution and evaluation' [30] we consider the implications of these findings for the design of future systems.
Molecular Editing and Assessment of the Cytotoxic Properties of Iejimalide and Progeny (2011)

Systematic variation of all substructures embedded into the framework of iejimalide B (2) led to a panel of synthetic analogues of this polyunsaturated macrolide, featuring structural modifications that are not accessible by derivatization of the natural lead compound itself. The assessment of the cytotoxicity of these compounds with the aid of a monolayer proliferation assay (12 human tumor cell lines in vitro) as well as a colony formation assay (24 human tumor xenografts ex vivo) revealed the exceptional potency of 2 and several of its synthetic congeners, with IC(50) values in the picomolar range for the most sensitive cell lines. Whereas structural modifications of the macrocycle or of the side chain generally lead to a decrease in activity, changes of the peptidic terminus are not only well accommodated but engender increased tumor selectivity as well. 2 and two of the most promising analogues were selected for in vivo studies in mice, in which their activity against human tumor xenografts of breast cancer (MAXF 401) and prostate cancer (PRXF PC-3M) was tested. In contrast to a previous report in the literature however, which had claimed in vivo activity for the parent iejimalides, these tests did not show a significant therapeutic effect against the chosen solid tumors upon intraperitoneal administration.
Real-time Cure Monitoring of Composites Using a Guided wave-based System with High Temperature Piezoelectric Transducers, Fiber Bragg Gratings, and Phase-shifted Fiber Bragg Gratings (2017)

An in-process, in-situ cure monitoring technique utilizing a guided wave-based concept for carbon fiber reinforced polymer (CFRP) composites was investigated. Two automated cure monitoring systems using guided-wave ultrasonics were developed for characterizing the state of the cure. In the first system, surface mounted high-temperature piezoelectric transducer arrays were employed for actuation and sensing. The second system motivated by the success of the first system includes a single piezoelectric disc, bonded onto the surface of the composite for excitation; fiber Bragg gratings (FBGs) and/or phase-shifted fiber Bragg gratings (PSFBGs) were embedded in the composite for distributed cure sensing. Composite material properties (viscosity and degree of cure) evolved during cure of the panels fabricated from Hexcel® IM7/8552 prepreg correlated well to the amplitude, time of arrival, and group velocity of the guided wave-based measurements during the cure cycle. In addition, key phase transitions (gelation and vitrification) were clearly identified from the experimental data during the same cure cycle. The material properties and phase transitions were validated using cure process modeling software (e.g., RAVEN®). The high-temperature piezoelectric transducer array system demonstrated the feasibility of a guided wave-based, in-process, cure monitoring and provided the framework for defect detection during cure. Ultimately, this system could provide a traceable data stream for non-compliance investigations during serial production and perform closed-loop process control to maximize composite panel quality and consistency. In addition, this system could be deployed as a “smart” caul/tool plate to existing production lines without changing the design of the aircraft/structure. With the second system, strain in low frequency (quasi-static) and the guided wavebased signals in several hundred kilohertz range were measured almost simultaneously using the same FBG or PS-FBG throughout the cure cycle. Also, the residual strain can be readily determined at the end of the cure. This system demonstrated a real-time, in-situ, cure monitoring system using embedded multiplexed FBG/PS-FBG sensors to record both guided wave-based signals and strain. The distinct advantages of a fiber optic-based system include multiplexing, small size, embedding, utilization in harsh environments, electrically passive operation, and electromagnetic interference (EMI) immunity. The embedded multiplexed FBG/PS-FBG fiber optic sensor can monitor the entire life-cycle of the composite structure from curing, post-cure/assembly, and in-service for creating “smart structures”.
Performance of PEM Liquid-Feed Direct Methanol - Air Fuel Cells (1995)

A direct methanol-air fuel cell operating at near atmospheric pressure, low-flow rate air, and at temperatures close to 60°C would tremendously enlarge the scope of potential applications. While earlier studies have reported performance with oxygen, the present study focuses on characterizing the performance of a PEM liquid feed direct methanol-air cell consisting of components developed in house. These cells employ Pt-Ru catalyst in the anode, Pt at the cathode and Nafion® 117 as the PEM. The effect of pressure, flow rate of air and temperature on cell performance has been studied. With air, the performance level is as high as 0.437 V at 300 mA/cm2 (90 °C, 20 psig, and excess air flow) has been attained. Even more significant is the performance level at 60°C, 1 atm and low flow rates of air (3–5 times stoichiometric), which is 0.4 V at 150 mA/cm2. Individual electrode potentials for the methanol and air electrode have been separated and analyzed. Fuel crossover rates and the impact of fuel crossover on the performance of the air electrode have also been measured. The study identifies issues specific to the methanol-air fuel cell and provides a basis for improvement strategies.
SYNTHETIC SUBSTITUTES FOR SKIN (1962)

CHARDACK, WILLIAM M. M.D.; MARTIN, MARY M. M.D.; JEWETT, THEODORE C. M.D.; BOYER, BYRON E. M.D. Author Information
Anticipating the future by watching unlabeled video. (2015)

In many computer vision applications, machines will need to reason beyond the present, and predict the future. This task is challenging because it requires leveraging ex-tensive commonsense knowledge of the world that is diffi-cult to write down. We believe that a promising resource for efficiently obtaining this knowledge is through the mas-sive amounts of readily available unlabeled video. In this paper, we present a large scale framework that capitalizes on temporal structure in unlabeled video to learn to antic-ipate both actions and objects in the future. The key idea behind our approach is that we can train deep networks to predict the visual representation of images in the future. We experimentally validate this idea on two challenging “in the wild ” video datasets, and our results suggest that learning with unlabeled videos significantly helps forecast actions and anticipate objects. 1.
A minimum-phase LU factorization preconditioner for Toeplitz matrices (1992)

A new preconditioner is proposed for the solution of an N x N Toeplitz system TNX = b, where TN can be symmetric indefinite or nonsymmetric, by preconditioned iterative methods. The preconditioner FN is obtained based on factorizing the generating function T(z) into the product of two terms corresponding, respectively, to minimum-phase causal and anticausal systems and therefore called the minimum-phase LU (MPLU) factorization preconditioner. Due to the minimum-phase property, IIFJ1II is bounded. For rational
Use of a Locked-Nucleic-Acid Oligomer in the Clamped-Probe Assay for Detection of a Minority <i>Pfcrt</i> K76T Mutant Population of <i>Plasmodium falciparum</i> (2005)

ABSTRACT Given the emergence of drug resistance and the high rate of polyclonal microorganism infections, the availability of a fast and sensitive test to detect minority mutant populations would be an improvement in the diagnosis of infectious diseases. A clamped-probe real-time PCR assay to diagnose the Plasmodium falciparum K76T mutation in clone populations was developed, using a wild-type-specific locked-nucleic-acid-containing oligomer to suppress wild-type PCR amplification and to enhance melting analysis with a mutation-specific detection probe.
Antiviral Compounds. I. Aliphatic Glyoxals, α-Hydroxyaldehydes and Related Compounds (1957)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAntiviral Compounds. I. Aliphatic Glyoxals, α-Hydroxyaldehydes and Related CompoundsBurris D. Tiffany, John B. Wright, Robert Bruce Moffett, Richard V. Heinzelman, Richard E. Strube, Brooke D. Aspergren, Edward H. Lincoln, and John L. WhiteCite this: J. Am. Chem. Soc. 1957, 79, 7, 1682–1687Publication Date (Print):April 1, 1957Publication History Published online1 May 2002Published inissue 1 April 1957https://pubs.acs.org/doi/10.1021/ja01564a042https://doi.org/10.1021/ja01564a042research-articleACS PublicationsRequest reuse permissionsArticle Views544Altmetric-Citations57LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Immunochemical and Biological Characteristics of a Human Autoantibody to Human Chorionic Gonadotropin and Luteinizing Hormone* (1988)

Anti-hCG/LH autoantibodies were found in the serum of an infertile woman a few days after an abortion which occurred after 46 days of amenorrhea. The antibody titer increased for approximately 4 more weeks, and then declined to low levels during a 14-month anovulatory period, after which regular menses resumed. Immunoglobulins isolated from a pool of serum obtained during the postabortion period neutralized the activity of both hCG and LH in an in vivo bioassay, and the binding affinity of the antibodies toward both hormones was high. When menses were resumed, there was a considerable reduction of the affinity toward LH. The variations in antibody titers and/or affinities can explain the sequence of fertilization, abortion, anovulatory period, and normalization of menses.
Pancreatic cancer detected by positron emission tomography with 18F-labelled deoxyglucose (1993)

In order to evaluate the utility of positron emission tomography (PET) with 18F-labelled deoxyglucose (FDG) for detection of pancreatic cancer 15 patients with pancreatic masses shown by computed tomography were investigated. Static PET scans covering an axial field of view of 15 cm were obtained 45 min after intravenous injection of 150-300 MBq FDG. Focally increased FDG accumulation was present in 12 out of 13 patients with histologically proven adenocarcinoma, in particular in eight of nine lymph node and four of five liver metastases. Scans of two patients with chronic pancreatitis confirmed by surgery revealed a normal FDG distribution. Contrast between tumour and normal tissue depended the metabolic situation prior to FDG injection. High ratios were found in fasting patients whereas no elevated FDG uptake was measured in an insulin-dependent diabetic suffering from carcinoma of the pancreatic head. We conclude that FDG PET might have the potential for detection and even differentiation of pancreatic carcinoma from chronic pancreatitis. Further studies are necessary to substantiate these preliminary findings and to optimize results in diabetic patients.
Sn-Mesoporphyrin Interdiction of Severe Hyperbilirubinemia in Jehovah’s Witness Newborns as an Alternative to Exchange Transfusion (2001)

The use of SnMP to moderate or prevent the development of severe hyperbilirubinemia in newborns (preterm, near-term, term with high PBCs [15-18 mg/dL], ABO-incompatibility; glucose-6-phosphate dehydrogenase deficiency) has been extensively studied in carefully conducted clinical trials the results of which have been reported earlier. This inhibitor of bilirubin production has demonstrated marked efficacy in moderating the course of hyperbilirubinemia in all diagnostic groups of unconjugated neonatal jaundice. The 2 cases described in this report confirmed the efficacy of SnMP in terminating progression of hyperbilirubinemia in infants in whom phototherapy had failed to sufficiently control the problem and whose parents, for religious reasons, would not permit exchange transfusions. Interdiction of severe hyperbilirubinemia by inhibiting the production of bilirubin with SnMP can be an effective alternative to the use of exchange transfusion in the management of severe newborn jaundice that has not responded sufficiently to light treatment to ease concern about the development of bilirubin encephalopathy.
Self-aligned titanium silicide device technology by NH3 plasma assisted thermal annealing (1987)

The self-aligned titanium silicide device technology has been studied by using NH3 plasma assisted thermal annealing and ion implant through titanium metal or silicide film. Enhanced surface nitridation of titanium by activated species suppresses lateral silicide growth and oxide contamination. NH3 plasma assisted annealing can be used as an effective method to form TiSi2 and activate implanted dopant. P+N junction and P channel metal–oxide–semiconductor field-effect transistor can be produced by boron implant through Ti metal or its silicide and the NH3 plasma assisted thermal annealing.
Inorganic–Organic Layered Materials Derived via the Hydrolysis and Polycondensation of Trialkoxy(alkyl)silanes (1997)

Abstract Triethoxy(alkyl)silanes containing 12—18 carbon atoms in the alkyl groups were hydrolyzed and polycondensed to form ordered structured materials. The XRD pattern of each condensed product showed sharp diffraction peaks with higher orders. The basal spacings approximately corresponded to twice the extended molecular length of the alkyl groups, and increased linearly as a function of the alkyl chain length. The SEM images of the products exhibited a platy morphology, and the 29Si CP/MAS NMR spectra revealed the formation of siloxane bonds with various silicon sites from T1 to T3 environments. All of these results indicated the formation of highly-organized inorganic–organic layered materials.
RE: INTRAVESICAL INTERLEUKIN-2 IN T1 PAPILLARY BLADDER CARCINOMA: REGRESSION OF MARKER LESION IN 8 OF 10 PATIENTS (1999)

No AccessJournal of UrologyCLINICAL UROLOGY: Letters to the Editor1 Nov 1999RE: INTRAVESICAL INTERLEUKIN-2 IN T1 PAPILLARY BLADDER CARCINOMA: REGRESSION OF MARKER LESION IN 8 OF 10 PATIENTS W. Den Otter, Z. Dobrowolski, A. Bugajski, B. Papla, A.P.M. Van der Meijden, J.W. Koten, T.A. Boon, M. Siedlar, and M. Zembala W. Den OtterW. Den Otter More articles by this author , Z. DobrowolskiZ. Dobrowolski More articles by this author , A. BugajskiA. Bugajski More articles by this author , B. PaplaB. Papla More articles by this author , A.P.M. Van der MeijdenA.P.M. Van der Meijden More articles by this author , J.W. KotenJ.W. Koten More articles by this author , T.A. BoonT.A. Boon More articles by this author , M. SiedlarM. Siedlar More articles by this author , and M. ZembalaM. Zembala More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)68213-4AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "RE: INTRAVESICAL INTERLEUKIN-2 IN T1 PAPILLARY BLADDER CARCINOMA: REGRESSION OF MARKER LESION IN 8 OF 10 PATIENTS." The Journal of Urology, 162(5), p. 1706 References 1 : Local low-dose IL-2 therapy. Hepato-Gastroenterology1999; 46: 1280. Google Scholar © 1999 by American Urological Association, Inc.FiguresReferencesRelatedDetails Volume 162Issue 5November 1999Page: 1706 Advertisement Copyright & Permissions© 1999 by American Urological Association, Inc.MetricsAuthor Information W. Den Otter More articles by this author Z. Dobrowolski More articles by this author A. Bugajski More articles by this author B. Papla More articles by this author A.P.M. Van der Meijden More articles by this author J.W. Koten More articles by this author T.A. Boon More articles by this author M. Siedlar More articles by this author M. Zembala More articles by this author Expand All Advertisement PDF downloadLoading ...
Mechanisms and effects of male genital tract infection on sperm quality and fertilizing potential: the andrologist's viewpoint (1999)

There are several mechanisms acting in synergism that can impair sperm characteristics of patients with accessory gland infection. In some cases, conventional sperm variables are disturbed with oligo and/or asthenozoospermia. In other patients, these sperm variables may appear normal, but the functional capacity of spermatozoa may be impaired. In particular, changes in the composition of the sperm membrane may result in reduced acrosome reactivity and capacity to fuse with the oolemma, and oxidative damage of the sperm DNA may induce mutagenesis. Changes in the biochemical make-up of seminal plasma can also reduce the in-vivo fertilizing capacity of spermatozoa, and infection-related disruption of the blood-testis barrier can induce the generation of anti-sperm antibodies and immunological infertility. Many of these functional abnormalities will not become evident upon 'basic semen analysis', which explains why some authors are unable to link infection of the accessory sex glands to subfertility. Also, functional and anatomical damage acquired as a result of infection is often permanent and not reversible by (antibiotic) treatment. Clearly, there are many more aspects of male accessory gland infection that require investigation. Available data should stimulate clinicians to place more emphasis on the prevention of infection-related infertility than on its treatment, as the latter is often unsuccessful.
Histopathological Evaluation of Griseofulvin Therapy in Lichen planus (1980)

In a double-blind trial on 44 patients having lichen planus, 500 mg griseofulvin-FP daily for 8 weeks produced significantly better results compared to a placebo. The clinical improvement was accompanied by corresponding histological changes.
Immunoassay Techniques in Environmental Analyses (2000)

Abstract In the 1980s, several Program Offices of the United States Environmental Protection Agency (USEPA) investigated the use of immunoassay methods for environmental applications with limited success. Most of the problems were with method ruggedness, i.e. they worked well in clean spiked matrices, but not very well on real world samples. The situation changed significantly in January of 1992, when the Office of Solid Waste (OSW) received its first rugged immunoassay method (for pentachlorophenol (PCP)) that worked on field samples. Several more followed, and through the early and mid‐1990s, the USEPA initiated use of immunoassay methodology in its hazardous waste program. The first group of methods incorporated into the OSW's methods compendium, Test Methods for Evaluating Solid Waste, or SW‐846, between 1993 and 1995 were a group of 10 enzyme‐linked immunosorbent assay (ELISA)‐based screening methods for various environmental analyte classes. These methods were officially ‘approved’ by the USEPA in July, 1997. We provided a great deal of training on these methods to raise the comfort level of the environmental community for their use. This chapter addresses several major topics including an overview of the USEPA's major Regulatory Programs; how analytical methods are used in Regulatory Programs; general guidelines for the development of screening methods; specific validation criteria for immunoassay methods; the current status of the USEPA immunoassay method development program; current and potential environmental applications for immunoassay technology; barriers to implementation of immunoassay methods and the steps being taken to overcome them; and future directions and new developments in immunoassay technology for regulatory programs. The overall future of the technology for environmental monitoring and analysis looks very bright. It offers a cost effective way to generate reliable information upon which to base sound environmental decisions.
Structure and Expression of a Cloned cDNA for Human (2′-5′)Oligoadenylate Synthetase1 (1986)

17S poly(A)+RNA, which hybridized to an oligonucleotide complementary to a part of the partial cDNA (E1cDNA) (Merlin et al. (1983) Proc. Natl. Acad. Sci. U.S. 80, 4904) for 2-5A synthetase, was isolated from interferon-treated human KB cells and used for cDNA cloning. Several overlapping cDNAs were cloned by using the oligonucleotide as a probe. Two of them were joined at their overlapping region, resulting in a cDNA (22-1 cDNA) of 1.4 kb containing a long open reading frame. When the cDNA was expressed in COS-7 cells with an eukaryotic promoter, active 2-5A synthetase was produced and localized mainly in the cytoplasm. The 5'-proximal ATG in 22-1 cDNA is followed immediately by another ATG. This second ATG was assumed to work as the initiator codon. If so, this enzyme comprises 363 amino acids.
A method for making microfilarial surveys on day blood (1939)

Journal Article A method for making microfilarial surveys on day blood Get access James Knott, M.D. James Knott, M.D. Chief Municipal Physician, St. Croix, Virgin Islands, U.S.A. Search for other works by this author on: Oxford Academic PubMed Google Scholar Transactions of The Royal Society of Tropical Medicine and Hygiene, Volume 33, Issue 2, 28 July 1939, Pages 191–196, https://doi.org/10.1016/S0035-9203(39)90101-X Published: 28 July 1939