gebhart/patrepeval huggingface dataset:
Neutralizing SQL Injection Attack Using Server Side Code Modification in Web Applications (2017)

Reports on web application security risks show that SQL injection is the top most vulnerability. The journey of static to dynamic web pages leads to the use of database in web applications. Due to the lack of secure coding techniques, SQL injection vulnerability prevails in a large set of web applications. A successful SQL injection attack imposes a serious threat to the database, web application, and the entire web server. In this article, the authors have proposed a novel method for prevention of SQL injection attack. The classification of SQL injection attacks has been done based on the methods used to exploit this vulnerability. The proposed method proves to be efficient in the context of its ability to prevent all types of SQL injection attacks. Some popular SQL injection attack tools and web application security datasets have been used to validate the model. The results obtained are promising with a high accuracy rate for detection of SQL injection attack.
Automatic Direct-Reading X-Ray Spectrometry. Application to Determinations of Silver (1961)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAutomatic Direct-Reading X-Ray Spectrometry. Application to Determinations of SilverJ. E. Moore, G. P. Happ, and D. W. StewartCite this: Anal. Chem. 1961, 33, 1, 61–64Publication Date (Print):January 1, 1961Publication History Published online1 May 2002Published inissue 1 January 1961https://pubs.acs.org/doi/10.1021/ac60169a017https://doi.org/10.1021/ac60169a017research-articleACS PublicationsRequest reuse permissionsArticle Views21Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effect of calfhood vaccination on transmission of bovine viral diarrhea virus under typical drylot dairy conditions (2001)

Findings suggest that calfhood vaccination may be an appropriate strategy to help reduce short-term transmission of some but not necessarily all strains of BVDV.
Mesenchymal Stem Cell Delivery Routes and Fate (2008)

MSC have been used in diverse animal disease models to investigate their regenerative capacity. Although the clinical outcome was often encouraging, the mode of action of the cells remains unresolved. Differentiation of MSC into cell types of their target organs was only rarely shown, with the exception of the musculoskeletal system. Thus, the effect of the cells on the clinical outcome in several disease models of tissue degeneration must be independent of trans-differentiation and caused by indirect or paracrine effects. Furthermore, tracking of the cells in vivo revealed that only a small proportion of the cells home and persists in the target sites, and that most of the cells are not detectable after 7∼14 days post transplantation. It seems that MSC can deliver a profound clinical effect without trans-differentiation, without homing to target organs in significant numbers and despite the cell's disappearance within short periods of time. These finding also suggest that the full potency of MSC has not yet been exploited in the current applications. Here we will provide an overview of the different routes used for cell delivery and the fate of the cells after transplantation. The effects on clinical outcome are discussed with respect to the role cell entrapment in non-target organs may play for the observed clinical effects.
Construction of Optimal Low Correlation Zone Sequence Sets Based on DFT Matrices (2012)

In this paper, we constructed a class of low correlation zone sequence sets derived from the interleaved technique and DFT matrices. When p is a prime such that p>3, p-ary LCZ sequence sets with parameters LCZ(pn-1,pm-1,(pn-1)/(pm-1),1) are constructed based on a DFT matrix with order p×p, which is optimal with respect to the Tang-Fan-Matsufuji bound. When p is a prime such that p≥2, pk-ary LCZ sequence sets with parameters LCZ(pn-1,pk-1,(pn-1)/(pk-1),1) are constructed based on a DFT matrix with order pk×pk, which is also optimal. These sequence sets are useful in certain quasi-synchronous code-division mutiple access (QS-CDMA) communication systems.
Independent sensitivity of human tumor cell lines to interferon and double-stranded RNA. (1984)

The antiproliferative effect of human interferons (IFNs) and double-stranded RNAs (dsRNAs) was measured in eight human tumor cell lines, five of which were derived from carcinomas of the bladder. Dose-response curves were generated for a 72-hr treatment period. The concentration of interferon or dsRNA necessary to inhibit tumor cell growth 50% compared to untreated cells was generated by linear regression analysis of the dose-response data. In the seven of eight cell lines in which a direct comparison could be made, IFN-beta was a more potent inhibitor than IFN-alpha. Polyriboinosinic acid X polyribocytidylic acid consistently gave an increased antiproliferative response compared to its mismatched analogue, rln X r(C12,U)n. Correlations could not be made between either IFN-alpha or IFN-beta and the dsRNA effect. No correlation was seen between IFN or dsRNA sensitivity and cell type, ability to bind IFN, growth rate, or tumorigenicity in nude mice. The antiproliferative effect of dsRNA was studied in the presence of antibodies against IFN-beta in HT1080 Cl 4, a cell line sensitive to both IFN and dsRNA, and A2182, a cell line relatively resistant to IFN-beta but sensitive to dsRNA. In both cell lines, the anti-IFN-beta antibodies inhibited the antiproliferative effect of the dsRNAs. After treatment with a concentration of dsRNA necessary to inhibit tumor cell growth 50% compared to untreated cells, a concentration of IFN-beta necessary to inhibit tumor cell growth 50% was induced in the HT1080 Cl 4 cells; however, only a low level of IFN-beta was detected in the culture medium of the A2182 cells.
[Effects of tumor suppressing gene TIP30/CC3 on the growth of tumor cells]. (2005)

Tumor suppressor gene TIP30/CC3 can inhibit the proliferation of tumor cells and interfere in its cell cycles. It can be used as a valuable tool for hepatoma biotherapy including gene therapy.
Central amyloid- -specific single chain variable fragment ameliorates A  aggregation and neurotoxicity (2013)

Anti-amyloid-β immunotherapies are a promising therapeutic approach for the treatment and prevention of Alzheimer's disease (AD). Single chain antibody fragments (scFv) are an attractive alternative to whole antibodies due to their small size, single polypeptide format and inability to stimulate potentially undesirable Fc-mediated immune effector functions. We have generated the scFv derivative of anti-Aβ monoclonal antibody, 1E8, known to target residues 17-22 of Aβ. Here we show that the soluble 1E8 scFv binds to the central region of Aβ with an affinity of ~55 nM and significantly reduces fibril formation of Aβ(1-42). Furthermore, 1E8 scFv ameliorates Aβ(1-42)-mediated toxicity in the PC12 cell line and murine primary neuronal cultures. This ability to both target the central region of Aβ and prevent Aβ(1-42) neurotoxicity in vitro makes it a promising therapeutic antibody building block for further functionalization, toward the treatment of AD.
The Effect of Electric Fields on Blue Phases (1991)

Abstract An experimental review on electric field effects in blue phases is presented. Electric fields have a profound effect on these phases which appear in chiral liquid crystals. In addition to producing elec-trostrictive effects on blue phase lattices, they also cause new field induced phases—tetragonal BPX, hexagonal BPH3D and BPH2D, and possible other phases yet to be identified. In recent experiments on BPIII for materials with negative dielectric anisotropy, it was found that electric fields cause a dramatic increase in the otherwise weak BPIII selective reflection. These experimental results were discussed with respect to possible models for the unknown structure of BPIII. Recently, efforts were also made to investigate the dynamics of different electrooptic effects more precisely.
<i>In vivo</i> evaluation of serotonergic agents and α‐adrenergic blockers on premature ejaculation by inhibiting the seminal vesicle pressure response to electrical nerve stimulation (1998)

Like serotonin, fluoxetine and clomipramine can reduce the pressure response of the seminal vesicle to ENS. Among these inhibitory agents, including prazosin, fluoxetine was the most effective and may be valuable for the clinical treatment of ejaculatory dysfunction in man.
Conversion Between Osmolality and Osmolarity of Infusion Solutions (2009)

In order to be applied into the body, intravenous fluids should be formulated to have an osmotic pressure similar to that of biological fluids. Physiologic acceptability of large-volume parenteral formulations in clinical practice is largely determined due to the osmotic effect of the dissolved solutes. Therefore, it is generally recommended that the labelling should list osmolarity. However, the declared osmolarity is not consistent with the principle of osmometry which measures osmolality. Then, the conversion of the measured osmolality to declared osmolarity is necessary. The conversion factor, defined as the ratio of molarity and molality of the solution, necessitates the measurement of the solution density and the expression of water content in solution. In this work, the relationship between molarity and molality of the aqueous solutions of nine parenteral solutes is studied. The equations for the interconversion between molarity and molality, employing the experimentally obtained mean molal volume of the dissolved solute, are proposed. The original equation allowing the estimation of the molal volume of the solute in aqueous solution from its true powder density is introduced and recommended for nonelectrolytes as well as the hydrates of electrolytes.
Photon-Number Squeezed Solitons from an Asymmetric Fiber-Optic Sagnac Interferometer (1998)

Direct photon-number squeezing is demonstrated, for the first time to our knowledge, in a nonlinear fiber-optic interferometer. Launching 126-fs solitons into a highly asymmetric Sagnac loop, the maximum photocurrent noise reduction was $3.9\ifmmode\pm\else\textpm\fi{}0.2\mathrm{dB}$ below shot noise, corresponding to $6.0\ifmmode\pm\else\textpm\fi{}0.9\mathrm{dB}$, when corrected for linear losses. The loop is a model system for squeezing generated by the interference of two pulses after nonlinear propagation through a fiber.
Tuning Lewis acidity using the reactivity of “frustrated Lewis pairs”: facile formation of phosphine-boranes and cationic phosphonium-boranes (2007)

The concept of "frustrated Lewis pairs" involves donor and acceptor sites in which steric congestion precludes Lewis acid-base adduct formation. In the case of sterically demanding phosphines and boranes, this lack of self-quenching prompts nucleophilic attack at a carbon para to B followed by fluoride transfer affording zwitterionic phosphonium borates [R(3)P(C(6)F(4))BF(C(6)F(5))(2)] and [R(2)PH(C(6)F(4))BF(C(6)F(5))(2)]. These can be easily transformed into the cationic phosphonium-boranes [R(3)P(C(6)F(4))B(C(6)F(5))(2)](+) and [R(2)PH(C(6)F(4))B(C(6)F(5))(2)](+) or into the neutral phosphino-boranes R(2)P(C(6)F(4))B(C(6)F(5))(2). This new reactivity provides a modular route to a family of boranes in which the steric features about the Lewis acidic center remains constant and yet the variation in substitution provides a facile avenue for the tuning of the Lewis acidity. Employing the Gutmann-Beckett and Childs methods for determining Lewis acid strength, it is demonstrated that the cationic boranes are much more Lewis acidic than B(C(6)F(5))(3), while the acidity of the phosphine-boranes is diminished.
Effects of copper-bearing montmorillonite on growth performance, digestive enzyme activities, and intestinal microflora and morphology of male broilers (2004)

Avian commercial male broiler chicks (n = 240), 1 d of age, were used to investigate the effects of copper-bearing montmorillonite (Cu-MMT) on growth performance, digestive enzyme activities, and intestinal microflora and morphology. The chicks were allocated to 4 treatments, each of which had 5 pens of 12 chicks per pen. The 4 treatments were basal diet only (control group), basal diet + 1.5 g/kg montmorillonite (MMT), basal diet + 36.75 mg/kg Cu, in the form of CuSO4, and basal diet + 1.5 g/kg Cu-MMT. The results showed that supplementation with Cu-MMT significantly improved growth performance compared with the control diet, and that chicks fed with Cu-MMT had higher average daily gain (ADG) than those fed with MMT or CuSO4. Supplementation with Cu-MMT significantly reduced the total viable counts of Escherichia coli and Clostridium in the small intestine and cecum. Supplementation with MMT or CuSO4 had no influence on intestinal microflora. Chicks fed with Cu-MMT had lower viable counts of E. coli in cecal contents than those fed with MMT or CuSO4. The addition of either MMT or Cu-MMT to the diet improved the activities of total protease, amylase, and lipase in the small intestinal contents but had no effect on those in the pancreas. Morphological measurements of the small intestinal mucosa of chicks indicated that dietary addition of MMT or Cu-MMT improved intestinal mucosal morphology.
A broadcast reference technique for self-calibrating of large antenna phased arrays (1989)

A modified phase-multilateration technique is proposed for calibrating the element locations of a flexible phased array. The technique requires several auxiliary beacons. The calibrating system measures the phase, relative to a broadcast reference, of each beacon signal at each array element. Automatic calibration of the differential phase delay in each antenna element signal path is included in the self-survey process. Digital beamforming is used for array signal processing. The beacon locations can be accurately or loosely known. For the system with loosely known beacon locations, an additional baseline measurement is required, and the beacon locations are treated as unknown variables. It is shown that a simple variable transformation can transform the mathematical equations of this technique into a form identical to that of the corresponding equations of previous cabled reference systems. The mathematical properties of the algorithm and its associated tolerance analysis are therefore readily available. A combination of the versions of this technique with accurately known and loosely known beacon locations is shown to have better performance than the individual version.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Spectroscopic study of polyphenylquinolines—materials with efficient intramolecular charge transfer (2013)

The energy structure and nature of intramolecular charge transfer have been determined for a series of synthesized 2,6-polyphenylquinolines (PPQs) containing resorcinol, oxygen, and phenylamine bridging groups between phenylquinoline cycles and possessing an arylene radical in the form of alkylated derivatives of carbazole or indolo[3,2-b]carbazole, as well as arylated derivatives of carbazole with nitro- and fluorine substituents. The analysis was based on data on their absorption spectra, photosensitivity, carrier photogeneration quantum efficiency, and luminescence. It is shown that the PPQ monomeric unit is a composite intramolecular charge-transfer complex (ICTC) between the donor arylene fragment and the acceptor quinoline cycle; the latter, in turn, is an ICTC between the donor bridging group and quinoline ring (when acceptor fluorine or nitro substituents are introduced into the carbazole structure, the complex becomes ternary), and the narrowest band gap (2.3 eV) corresponds to the PPQ having a phenylamine bridging group and a fragment of indolo[3,2-b]carbazole.
Human tears: osmotic characteristics. (1983)

Using a freezing point depression method, requiring volumes of only 200 nanoliters, the osmolalities of 324 tear samples collected at consecutive 10-minute intervals throughout 8.5-hour periods from each of six healthy young adults were measured. The population mean was found to be 318 mOsm/kg, with a population median of 315 mOsm/kg. Individual subject means ranged from 310 to 334 mOsm/kg. Short-term oscillations were observed for all subjects, with a net positive rate toward hypertonicity for the population of 1.43 mOsm/kg X hr-1 as the day progressed. Two subjects did demonstrate mild net rates of decrease, however. All eyes in the study were asymptomatic, suggesting a broader range of tear osmotic pressure among normals than previously suspected.
Organic Light‐Emitting Transistors Based on Solution‐Cast and Vacuum‐Sublimed Films of a Rigid Core Thiophene Oligomer (2005)

A new organic multifunctional material, a rigid core thiophene oligomer, has been designed and synthesized. In both solution-processed and vacuum-sublimed films, the delicate balance of forces needed to obtain a supramolecular organization that imparts good charge transport and electroluminescence has been achieved, with the films being successfully employed as active layers in organic light-emitting (field-effect) transistors (see Figure).
Resource-Efficient DNNs for Keyword Spotting using Neural Architecture Search and Quantization (2021)

This paper introduces neural architecture search (NAS) for the automatic discovery of small models for keyword spotting (KWS) in limited resource environments. We employ a differentiable NAS approach to optimize the structure of convolutional neural networks (CNNs) to maximize the classification accuracy while minimizing the number of operations per inference. Using NAS only, we were able to obtain a highly efficient model with 95.4% accuracy on the Google speech commands dataset with 494.8 kB of memory usage and 19.6 million operations. Additionally, weight quantization is used to reduce the memory consumption even further. We show that weight quantization to low bit-widths (e.g. 1 bit) can be used without substantial loss in accuracy. By increasing the number of input features from 10 MFCC to 20 MFCC we were able to increase the accuracy to 96.3% at 340.1 kB of memory usage and 27.1 million operations.
Breast cancer detection using automated whole breast ultrasound and mammography in radiographically dense breasts (2009)

AWBU resulted in significant cancer detection improvement compared with mammography alone. Additional detection and the smaller size of invasive cancers may justify this technology's expense for women with dense breasts and/or at high risk for breast cancer.
Abrogation of wild-type p53 mediated growth-inhibition by nuclear exclusion. (1996)

We used clone 6 cells (rat embryo fibroblasts transformed by the temperature sensitive mutant p53val135 and an activated H-ras-gene (Michalovitz et al., 1990)), growth arrested at 32 degrees C, as a model to analyse whether and how transformed cells, growth-arrested by an overexpressed wild-type p53, might overcome p53-mediated growth inhibition. When clone 6 cells were kept at 32 degrees C for about 2 weeks, foci of cells appeared which grew temperature-independent. Analysis of individual clones of such cell demonstrated that the ectopically expressed tsp53-gene had not been altered by an additional mutation, but that the tsp53 in these cells at 32 degrees C had lost its ability to upregulate expression of the p53 target genes waf1 and mdm2. This loss of p53-specific transactivation correlated with nuclear exclusion of the tsp53 at 32 degrees C, which was most likely mediated by cytoplasmic retention of the tsp53 protein via short-lived anchor proteins. Cytoplasmic retention of the tsp53 at 32 degrees C was also observed in PC12 pheochromocytoma cells ectopically expressing tsp53val135, there occurring without specific selection. Also in these cells nuclear exclusion of the tsp53 correlated with loss of p53 mediated growth inhibition. Nuclear exclusion of p53 thus might serve as an epigenetic mechanism to eliminate the growth-inhibitory function of p53.
In Vivo Cleavage of Recombinant VWF Upon Intravenous Administration in Preclinical and Clinical Settings (2011)

Abstract Abstract 1222 Von Willebrand factor (VWF) is composed of a series of multimers with a molecular size ranging from 600 to 20,000 kDa. The ultra-high molecular weight (UHMW) portion of VWF multimers is more efficient in platelet interactions than the lower molecular weight portion, and as such it might have a thrombogenic potential under certain pathologic conditions. The concentration of UHMW multimers in healthy individuals' blood is low because the circulating specific metalloprotease ADAMTS13 rapidly cleaves UHMW VWF upon its release into the circulation. A recombinant VWF (rVWF) expressed in CHO cells has been developed as a new drug candidate for treating patients with VWF deficiency. Since this protein is not cleaved by ADAMTS13 during the expression phase, it has a high portion of UHMW multimers, similar to the human VWF stored in Weibel-Palade bodies of endothelial cells. During the development phase of rVWF in vitro experiments showed that when treated under mild denaturing conditions or under shear, the molecule was susceptible to ADAMTS13 of human or animal origin. Here we present data from preclinical studies where analyzing the ex vivo samples showed the ADAMTS13-mediated cleavage of intravenously applied UHMW-containing rVWF. In good correlation with the in vitro results, studies in rabbits and cynomolgus monkeys showed that the ADAMTS13-specific cleavage fragments appeared as soon as 15 minutes after application, as visualized by immunoblot analysis. The appearance of cleavage bands coincided with the decrease in multimer numbers, indicating that rVWF had been specifically cleaved by endogenous ADAMTS13 in the circulation. The effect was species-dependent, only a low or minimal cleavage was observed in different mice strains. A recently completed Phase I clinical study clearly demonstrated that rVWF administered intravenously to severe VWD patients in a dose-range of 7.5 to 50 VWF:RCo U/kg body weight was rapidly processed in the circulation, resulting in the disappearance of the UHMW multimers with visible cleavage fragments, as shown by immunoblot and high resolution multimer analysis. No thrombotic adverse events were seen during the study, underlying the suitability of the UHMW-containing rVWF for treating VWD patients. Disclosures: Varadi: Baxter Innovations GmbH: Employment. Rottensteiner:Baxter Innovations GmbH: Employment. Schreiner:Baxter Innovations GmbH: Employment. Gritsch:Baxter Innovations GmbH: Employment. Ehrlich:Baxter Innovations GmbH: Employment. Scheiflinger:Baxter Innovations GmbH: Employment. Turecek:Baxter Innovations GmbH: Employment.