gebhart/patrepeval huggingface dataset:
The antithrombin-binding sequence of heparin (1981)

Conference Article| December 01 1981 The antithrombin-binding sequence of heparin ULF LINDAHL; ULF LINDAHL 1Department of Medical and Physiological Chemistry, Swedish University of Agricultural Sciences, The Biomedical Center, P.O. Box 575, S-751 23 Uppsala, Sweden Search for other works by this author on: This Site PubMed Google Scholar LENNART THUNBERG; LENNART THUNBERG 1Department of Medical and Physiological Chemistry, Swedish University of Agricultural Sciences, The Biomedical Center, P.O. Box 575, S-751 23 Uppsala, Sweden Search for other works by this author on: This Site PubMed Google Scholar GUDRUN BÄCKSTRÖM; GUDRUN BÄCKSTRÖM 1Department of Medical and Physiological Chemistry, Swedish University of Agricultural Sciences, The Biomedical Center, P.O. Box 575, S-751 23 Uppsala, Sweden Search for other works by this author on: This Site PubMed Google Scholar JOHAN RIESENFELD JOHAN RIESENFELD 1Department of Medical and Physiological Chemistry, Swedish University of Agricultural Sciences, The Biomedical Center, P.O. Box 575, S-751 23 Uppsala, Sweden Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1981) 9 (6): 499–501. https://doi.org/10.1042/bst0090499 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation ULF LINDAHL, LENNART THUNBERG, GUDRUN BÄCKSTRÖM, JOHAN RIESENFELD; The antithrombin-binding sequence of heparin. Biochem Soc Trans 1 December 1981; 9 (6): 499–501. doi: https://doi.org/10.1042/bst0090499 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1981 Biochemical Society1981 Article PDF first page preview Close Modal You do not currently have access to this content.
The Exclusion of Persons with Visual Impairment in Nigerian Academic Libraries' Websites (2017)

Libraries facilities and resources are expected to be accessible to patrons including people with disabilities. The experience in Nigeria appears to dictate otherwise.This study therefore examines the extent of inclusion and exclusion of persons with visual impairment with respect to access the contents of websites of Nigerian academic libraries. Data used for this study were derived from content analysis of websites of the first top ten universities in the webometric ranking of universities in Nigeria, The analysis was based on the checklist of the International Federation of Library Associations and Institutions (IFLA). This study discovered that only two of the top ten university libraries in Nigeria have web links on disability resources for persons with disabilities. The study shows a high level of exclusion of persons with visual impairments in the websites of the leading university libraries in Nigeria. The findings suggests that the websites of the leading university libraries in Nigeria require additional information to be considered inclusive. The study concludes with recommendations and implications for policy formulation concerning the need for a more inclusive culture in the university libraries to accommodate persons with visual impairment.
Facile Fabrication of Metal Nanoparticle/Graphene Oxide Hybrids: A New Strategy To Directly Illuminate Graphene for Optical Imaging (2011)

With unique structure and extraordinary properties, graphene has attracted tremendous attention in a wide range of fields recently. In terms of its biomedical applications, graphene has been used to be biosensors and drug carriers, including in vitro and in vivo studies. Therefore, how to clarify the behaviors of graphene in organism is a significant and long-term challenge. For that purpose, fabricating graphene-based materials which can give off some measurable signals become a fascinating topic. In this study, we report a facile noncovalent strategy to fabricate metal nanoparticle/graphene oxide (MNP/GO) hybrids, which can be used to directly illuminate graphene for optical imaging by employing the strong localized surface plasmon resonance (LSPR) light scattering of MNPs as an effective signal reporter, and thus the profiles of graphene can be observed with a dark-field microscope. The formation of MNP/GO hybrids has been confirmed successfully, and these new nanocomposites assembled from individual building blocks can be promising candidates for the applied purposes of biological imaging, drug delivery, and cancer therapy owing to their collective properties.
Gradient Index Polymer Optical Waveguide Patterned by Ultraviolet Irradiation (1989)

A new fabricating technique which is capable of easy pattern formation in gradient index polymer optical waveguides is proposed. Waveguides are obtained by diffusion and fixing of monomers with low refractive indices into a gel patterned by ultraviolet irradiation. The gradient index profiles can be selectively formed in the irradiated parts due to the difference in diffusion rate of monomers between regions in the same substrate. Waveguide optical properties are also demonstrated.
Microfilaria in thyroid gland fine needle aspiration cytology - an unusual finding (2006)

Involvement of thyroid gland by filariasis is an unusual finding. We report a case in which microfilaria was found in thyroid aspirate smear. Patient did not have any symptoms or signs suggestive of filariasis. The patient was treated with diethylcarbamazine and a later hemithyroidectomy was performed. We reviewed the literature and discussed possible reasons for finding a microfilaria in thyroid gland. KEYWORDS : microfilaria, aspiration cytology, thyroid gland Nigerian Journal of Otorhinolaryngology Vol. 3(1) 2006: 36-38
The Bischler-Napieralski Reaction of N-(3, 4-Dimethoxyphenethyl) urea (1962)

N-(3, 4-Dimethoxyphenethyl) urea, obtained by heating of 3, 4-dimethoxyphenethyl-amine hydrochloride with urea, was cyclized to 1-amino-6, 7-dimethoxy-3, 4-dihydroisoquinolinium chloride (II or II′) with phosphorous pentoxide and phosphoryl chloride. (II) or (II′) gave N-(2-cyano-4, 5-dimethoxyphenethyl) benzenesulfonamide (III) when it was treated with benzenesulfonyl chloride in alkaline solution.
Charge Coupled Device (CCD) Analog Signal Processing (1975)

International Telemetering Conference Proceedings / October 14-16, 1975 / Sheraton Inn, Silver Spring, Maryland
Optical and transport properties of lanthanum-doped stannate BaSnO<sub>3</sub> (2007)

BaSnO3 crystallizes in a cubic perovskite structure and exhibits insulating behaviour. It can be made conducting by reducing a small fraction of Sn4+ into Sn2+ under an O2-free atmosphere. This can be achieved through the solid solution Ba1−xLaxSnO3−δ which is a mixed phase for x > 0.02, behaviour readily understood in terms of the lone pair cation Sn2+. The magnetic susceptibility was measured down to 4.2 K and is less than 1.7 × 10−5 emu cgs mol−1 consistent with collective electron behaviour. The Mössbauer spectrum exhibits a wide unsplit peak with a quadrupole doublet of 3.18 mm s−1 and an isomer shift of 0.12 mm s−1 characteristic of Sn4+and corroborating the delocalization of the stereo chemical pair 5s2. The band gap Eg was found to be 3.12 eV; further indirectly allowed inter-band transition occurs at 2.85 eV. The transport properties of Ba0.98La0.02SnO3−δ indicate n-type conductivity (σ300 K = 4.03 Ω−1 cm−1), little temperature dependence, with an activation energy ΔE of ∼1 meV and an electron mobility μ300 K ∼ 0.1 cm2 V−1 s−1, thermally activated. The conduction occurs by small polaron hopping between mixed valence Sn4+/2+ ions. The observed conductivity is greater than that coming from La-substitution with one-electron doping implying the existence of oxygen vacancies. The electrons are believed to travel in the Sn-5s conduction band with an effective mass of 3.7 mo. The non-linear dependence of Ln σ versus T−1 at low temperatures could result from a predominant variable range hopping as suggested by the linear variation of log σ versus T−0.25. The electron localization may be attributed to the random distribution of lanthanum as well as oxygen vacancies.
A combination of PZT and EMAT transducers for interface inspection (2002)

A PZT (Lead Zirconate-Titanate) transducer requires a couplant to send and receive mechanical waves. This requirement is a major shortcoming of the PZT technique for use in field applications. In the laboratory environment careful considerations and surface treatments are required to use PZT because the couplant can affect the consistency of experimental results. One alternative to overcome this shortcoming is the use of EMAT (ElectroMagnetic Acoustic Transducer). However, EMAT gives relatively low transmitted ultrasonic energy, with low signal to noise ratio, and the induced energy is critically dependent on the probe proximity to the test object. These are not desirable properties for NDT (nondestructive testing) of civil infrastructures. That is why, in this paper, a combination of PZT and EMAT is introduced for investigating reinforced concrete structures. Interface defects between steel bars and concrete are investigated by this technique. It is shown that the PZT-EMAT combination is very effective for steel bar-concrete interface inspection and the guided waves are useful for nondestructive testing of civil infrastructures.
Cloning and sequencing of mouse collagenase cDNA Divergence of mouse and rat collagenases from the other mammalian collagenases (1992)

Mouse collagenase cDNA was cloned and sequenced. The deduced amino acid sequence was compared to those of the other mammalian collagenases and related matrix metalloproteinases. These comparisons, as well as those of some enzymatic properties, show that the rodent (mouse and rat) interstitial collagenases are very similar but differ more from the other interstitial collagenases than does human neutrophil collagenase. This supports the hypothesis that the order Rodentia is an outgroup to the other eutherian (placental) mammalian orders.
Grating-coupled surface plasmons at microwave frequencies (1999)

This work presents a detailed investigation of electromagnetic coupling to the surface plasmon-polariton (SPP) at microwave frequencies. We have recorded the wavelength-dependent reflectivity from a metallic sinusoidal diffraction grating of pitch 15 mm. In order to minimize the problems associated with nonplanar incident wavefronts, we have developed an apparatus that collimates the incident beam. We illustrate resonant coupling to the SPP at wavelengths of the order of 10 mm. The wavelength-dependent reflectivities recorded have been successfully fitted using a differential formalism of conical diffraction with a single set of grating parameters describing the grating profile and metal permittivity.
Using Discrete Event Simulation for Programming Model Exploration at Extreme-Scale: Macroscale Components for the Structural Simulation Toolkit (SST). (2015)

Discrete event simulation provides a powerful mechanism for designing and testing new extreme- scale programming models for high-performance computing. Rather than debug, run, and wait for results on an actual system, design can first iterate through a simulator. This is particularly useful when test beds cannot be used, i.e. to explore hardware or scales that do not yet exist or are inaccessible. Here we detail the macroscale components of the structural simulation toolkit (SST). Instead of depending on trace replay or state machines, the simulator is architected to execute real code on real software stacks. Our particular user-space threading framework allows massive scales to be simulated even on small clusters. The link between the discrete event core and the threading framework allows interesting performance metrics like call graphs to be collected from a simulated run. Performance analysis via simulation can thus become an important phase in extreme-scale programming model and runtime system design via the SST macroscale components.
Thermal-Hydraulic System Codes in Nulcear Reactor Safety and Qualification Procedures (2008)

In the last four decades, large efforts have been undertaken to provide reliable thermal-hydraulic system codes for the analyses of transients and accidents in nuclear power plants. Whereas the first system codes, developed at the beginning of the 1970s, utilized the homogenous equilibrium model with three balance equations to describe the two-phase flow, nowadays the more advanced system codes are based on the so-called “two-fluid model” with separation of the water and vapor phases, resulting in systems with at least six balance equations. The wide experimental campaign, constituted by the integral and separate effect tests, conducted under the umbrella of the OECD/CSNI was at the basis of the development and validation of the thermal-hydraulic system codes by which they have reached the present high degree of maturity. However, notwithstanding the huge amounts of financial and human resources invested, the results predicted by the code are still affected by errors whose origins can be attributed to several reasons as model deficiencies, approximations in the numerical solution, nodalization effects, and imperfect knowledge of boundary and initial conditions. In this context, the existence of qualified procedures for a consistent application of qualified thermal-hydraulic system code is necessary and implies the drawing up of specific criteria through which the code-user, the nodalization, and finally the transient results are qualified.
Comparison of Slope, Wave Height, and Radar Spectra, Slope and Hydrodynamic Modulation of Radar Scatter from the Sea (2005)

Description of Ocean waves usually depends on point measurements of wave height. The important vector slope of the ocean must usually be derived either from point measurements and linear assumptions or from pitch-and-roll buoys that cannot be in the radar footprint. We developed a 35-GHz vector slope gaugehat- terometer using a single switched-beam antenna. It can measure three adjacent height profiles of the ocean, from which we can derive two orthogonal components of the slope. We used the vector slope gauge during the SAXON-FFN experiment in November, 1990. Simultaneous measurements of the orthogonal components of the long-wave slopes and the backscattered power permit determination of the relative contribution to the overall modulation of the radar signal by slope modulation and hydrody- namic modulation of Bragg-resonant ripple amplitude.
AN HYMENOPTEROUS INSECT, THE PARASITOID <i>ITOPLECTIS CONQUISITOR</i>, REARED AXENICALLY ON A CHEMICALLY-DEFINED SYNTHETIC DIET (1970)

Abstract An unique development in insect dietetics is announced, namely, the rearing of an hymenopteran — Itoplectis conquisitor (Say), an ichneumonid endoparasitoid of other insects — axenically on a chemically-defined synthetic diet. First heuristic attempts produced a yield of about 17% adults.
National Models for Regulation of the Health Professions (2005)

The way in which the health professions are regulated is undergoing considerable change. The principle of peer review that has underpinned the regulatory model since the 1800s is under challenge, with increasing recognition that the professions alone are not always best placed to define what is in the public interest. The article argues that the pressure to reform is driven primarily by workforce shortages and the need for the regulatory arrangements to provide the levers necessary to drive a more flexible, responsive and sustainable health workforce. It examines the relationship between profession-specific regulatory structures and the contested division of labour in healthcare. It identifies an international trend towards breaking down the barriers between professions that have been maintained in part through profession-specific regulatory structures. It examines some alternative legislative models for giving effect to recent decisions by the Council of Australian Governments, to establish national cross-profession schemes for registration of the health professions and accreditation of their education and training.
Nitric Oxide Controls Src Kinase Activity through a Sulfhydryl Group Modification-mediated Tyr-527-independent and Tyr-416-linked Mechanism (1999)

c-Src kinase was activated when either murine NIH3T3 fibroblast cells or immunoprecipitated c-Src proteins were treated with nitric oxide generator, S-nitroso-N-acetyl penicillamine (SNAP) or sodium nitroprusside. Nitric oxide (NO) scavenger hemoglobin and N(2)O(3) scavenger homocysteine abolished the SNAP-mediated c-Src kinase activation. Phosphoamino acid analysis and peptide mapping of in vitro labeled phospho-c-Src proteins revealed that SNAP promoted the autophosphorylation at tyrosine, which preferentially took place at Tyr-416. Peptide mapping of in vivo labeled c-Src kinase excluded the involvement of phospho-Tyr-527 dephosphorylation in the SNAP-mediated activation mechanism. Correspondingly, protein-tyrosine phosphatase inhibitor Na(3)VO(4) did not abolish the SNAP-mediated activation of Src kinase, and the constitutively activated v-Src kinase was also further up-regulated in activity by SNAP. SNAP, however, failed to up-regulate the kinase activity of Phe-416 mutant v-Src. 2-Mercaptoethanol or dithiothreitol, which should disrupt N(2)O(3)-mediated S-nitrosylation and subsequent formation of the S-S bond, abolished the up-regulated catalytic activity, and the activity was regained after re-exposing the enzyme to SNAP. Exposure of Src kinase to SNAP promoted both autophosphorylation and S-S bond-mediated aggregation of the kinase molecules, demonstrating a linkage between the two events. These results suggest that the NO/N(2)O(3)-provoked S-nitrosylation/S-S bond formation destabilizes the Src structure for Tyr-416 autophosphorylation-associated activation bypassing the Tyr-527-linked regulation.
Current Status of Marketing, Constraints and Farmer's Share in Consumer Price of Guava in Kaushambi District of Uttar Pradesh (2013)

Present study was carried out (n=120) to find out the various channels involved in the marketing of guava fruits and to study the constraints encountered by the guava farmer of Kaushambi district of Uttar Pradesh. The average family size of guava farmers was 5.25 with average male and female 2.8 and 2.44, respectively. Average literacy rate among the famers families was 43.49.However, 30.42 per cent male and 26.08 per cent female were illiterate. There were seven different types of marketing channels which were involved in guava marketing. Out of seven marketing channels involved in guava marketing, first channel was found to be efficient and the remaining were less efficient in farmer's share in consumer price. Farmers faced several constraints related to marketing, storage and financial problems. High involvement of middleman's is hampering the profitability of guava farmers. Guava farmers are facing several constraints related to marketing, storage and finance. Hence, to improve the productivity of guava farm and guava farmers, the constraints and problems should be resolved at priority basis. Therefore, policy makers and administrators have to take initiative to provide efficient services to benefit the producers.
Isolation and Characterization of Adult Human Liver Progenitors from Ischemic Liver Tissue Derived from Therapeutic Hepatectomies (2008)

Recent evidence suggests that progenitor cells in adult tissues and embryonic stem cells share a high resistance to hypoxia and ischemic stress. To study the ischemic resistance of adult liver progenitors, we characterized remaining viable cells in human liver tissue after cold ischemic treatment for 24-168 h, applied to the tissue before cell isolation. In vitro cultures of isolated cells showed a rapid decline of the number of different cell types with increasing ischemia length. After all ischemic periods, liver progenitor-like cells could be observed. The comparably small cells exhibited a low cytoplasm-to-nucleus ratio, formed densely packed colonies, and showed a hepatobiliary marker profile. The cells expressed epithelial cell adhesion molecule, epithelial-specific (CK8/18) and biliary-specific (CK7/19) cytokeratins, albumin, alpha-1-antitrypsin, cytochrome-P450 enzymes, as well as weak levels of hepatocyte nuclear factor-4 and gamma-glutamyl transferase, but not alpha-fetoprotein or Thy-1. In vitro survival and expansion was facilitated by coculture with mouse embryonic fibroblasts. Hepatic progenitor-like cells exhibit a high resistance to ischemic stress and can be isolated from human liver tissue after up to 7 days of ischemia. Ischemic liver tissue from various sources, thought to be unsuitable for cell isolation, may be considered as a prospective source of hepatic progenitor cells.
Effect of the time-of-day of training on explicit memory (2008)

Studies have shown a time-of-day of training effect on long-term explicit memory with a greater effect being shown in the afternoon than in the morning. However, these studies did not control the chronotype variable. Therefore, the purpose of this study was to assess if the time-of-day effect on explicit memory would continue if this variable were controlled, in addition to identifying the occurrence of a possible synchronic effect. A total of 68 undergraduates were classified as morning, intermediate, or afternoon types. The subjects listened to a list of 10 words during the training phase and immediately performed a recognition task, a procedure which they repeated twice. One week later, they underwent an unannounced recognition test. The target list and the distractor words were the same in all series. The subjects were allocated to two groups according to acquisition time: a morning group (N = 32), and an afternoon group (N = 36). One week later, some of the subjects in each of these groups were subjected to a test in the morning (N = 35) or in the afternoon (N = 33). The groups had similar chronotypes. Long-term explicit memory performance was not affected by test time-of-day or by chronotype. However, there was a training time-of-day effect [F (1,56) = 53.667; P = 0.009] with better performance for those who trained in the afternoon. Our data indicated that the advantage of training in the afternoon for long-term memory performance does not depend on chronotype and also that this performance is not affected by the synchronic effect.