gebhart/patrepeval huggingface dataset:
Range of Thermal Treatment Upon the Mechanical Characteristics of PLLA Coiled Stents (2009)

Stents have been used as a medical device to restore blood flow in stenosed vessels. During this process of stent expansion, the balloon and stent could damage the endothelial lining of the vascular wall [Grewe, Farb] and alter the mechanical stress states of various tissue components. The subsequent tissue re-growth and vascular remodeling have been implicated among the causes leading to restenosis. Stent designs vary over a wide range from materials used, geometric shapes, fabrication methods, treatments, among many other parameters. There are many different stent designs. We have developed an internally coiled, furled helical PLLA fiber stent at our institution [Su 03, Zilberman 02, 04, 05]. We have previously shown the effect of 62°C thermal annealing on the expansive characteristics of this stent [Welch 08].
Effective Web caching for GPRS networks (2002)

During recent years, providing Web access to mobile users has become a major focus of the wireless network operations. A number of Web caching schemes have been proposed to improve response time of wireless Web access. Nevertheless, none of these schemes fit well into the GPRS model, which is an IP-based packet-switching extension of GSM. In this paper, various factors that must be considered in designing a Web caching scheme for GPRS are discussed. By taking those factors into account, we employ a known Web caching scheme, CNP, and extend its support of Web access for wireline networks into wireless GPRS environments. We also present how to incorporate CNP to deal with the Web proxy placement problem for GPRS.
Electrochemical engineering principles (1991)

1. Introduction. 2. Basic Concepts. 3. Thermodynamics. 4. Phase Equilibrium. 5. Electrode Kinetics. 6. Ionic Mass Transport. 7. Modeling and Simulation. 8. Experimental Methods. 9. Applications. Appendix A: Conversion Factors and Fundamental Constants. Appendix B: Standard Electrode Potentials. Appendix C: Equivalent Conductances. Appendix D: Activity Coefficients of Electrolytes at 25 degrees C. Appendix E: Mass Transport Correlations. Appendix F: Computer Program for a One-dimensional Cell. Appendix G: Computer Program for a Two-dimensional L-cell.
PiggyData: reducing CSMA/CA collisions for multimedia and TCP connections (2003)

This paper presents a scheme to improve the efficiency of radio MAC protocols in the case of bidirectional connections, like TCP connections and multimedia streams. First, the impact of directionality over the contention process is analysed. Then the PiggyData scheme is presented, which decreases the collision rate and overhead of bidirectional traffic over MAC protocols based on CSMA/CA. Finally, the new protocol is simulated in various scenarios to show how it performs.
Clustering and profiling of customers using RFM for customer relationship management recommendations (2017)

The problem faced by the company is how to determine potential customers and apply CRM (Customer Relationship Management) in order to perform the right marketing strategy, so it can bring benefits to the company. This research aims to perform clustering and profiling customer by using the model of Recency Frequency and Monetary (RFM) to provide customer relationship management (CRM) recommendation to middle industrial company. The method used in this study consists of four steps: data mining from transaction history data of customer sales, data mining modeling using RFM with K-Means algorithm and customer classification with desicion tree (J48), determination of customer loyalty level and recommendation of customer relationship management (CRM) on the medium-sized industry. This research produces RFM data mining model for medium industrial companies. In addition, the results of the study provide recommendations of four customer segments and characteristics of each customer to perform customer relationship strategy.
<i>In Vitro</i> and <i>in Vivo</i> Anti-Leishmanial Activity of Triterpenoid Saponins Isolated from <i>Maesa </i><i>b</i><i>alansae</i> and Some Chemical Derivatives (2004)

The methanolic extract from the leaves of the Vietnamese medicinal plant Maesa balansae showed potent in vitro and in vivo activity against the tropical protozoal parasite Leishmania infantum. Bioassay-guided purification of the extract led to the identification of six triterpenoid saponins, maesabalides I-VI (1-6), each having a strong and specific anti-leishmanial activity. Maesabalide III (3) and IV (4) were the most potent with IC(50) values against intracellular amastigotes of about 7 and 14 ng/mL. In comparison, the IC(50) value of sodium stibogluconate, the reference drug for treatment of leishmaniasis, is only 5.6 microg/mL. No cytotoxicity was present on a human fibroblast (MRC-5) cell line (CC(50) > 32 microg/mL). In vivo evaluation in the BALB/C mouse model demonstrated that >90% reduction of liver amastigote burdens was obtained 1 week after a single subcutaneous dose at 0.2-0.4 mg/kg was administered. Several chemical derivatives of maesabalides I-VI were prepared in order to study the structure-activity relationship.
An Experiment in Educational Freedom (1975)

(1975). An Experiment in Educational Freedom. Improving College and University Teaching: Vol. 23, Classrooms: Learning Withing Walls, pp. 243-244.
Stabilization of Holographic Fringes by FM Feedback (1968)

A method of stabilizing holographic or interferometric fringes using frequency compensation is described. An analysis is given which shows that fringe stabilization by frequency modulated feedback has an advantage over phase compensation feedback for certain interferometric configurations. Experimental results obtained using FM feedback are presented.
RELEASE (1938)

Journal Article RELEASE Get access Margaret Elizabeth Rhodes Margaret Elizabeth Rhodes Search for other works by this author on: Oxford Academic Google Scholar English: Journal of the English Association, Volume 2, Issue 7, 1938, Pages 28-a–28, https://doi.org/10.1093/english/2.7.28-a Published: 01 April 1938
Synthesis of [<sup>14</sup>C]zolpidem (1986)

Abstract The synthesis of [ 14 C]Zolpidem, a new hypnotic agent having a non‐benzodiazepine structure, is described. This compound was synthesised in a 64% overall radio‐chemical yield from potassium[ 14 C]cyanide and with a specific radioactivity of 56 mCi/mmol. It was used for pharmacokinetic and drug metabolism studies.
U-Prove Technology Overview V1.1 (Revision 2) (2013)

The U-Prove technology can be used to reconcile seemingly conflicting security and privacy requirements in electronic communication and transaction systems. This overview explains the foundational features of the U-Prove technology as specified in the U-Prove Cryptographic Specification V1.1 (Revision 2).
An adaptive two-dimensional channel estimator for wireless OFDM with application to mobile DVB-T (2000)

An adaptive channel estimator is proposed and investigated to improve the performance of the receiver for pilot aided wireless and mobile OFDM systems. The estimator consists of a two-dimensional Wiener filter which is implemented as a cascade of two one-dimensional filters. We propose an efficient algorithm for adaptation to time varying channels of the second filter. The method is applied to the Terrestrial Digital Video Broadcasting System (DVB-T), which was originally specified for fixed receivers and which is in the process of being extended for mobile reception. The results are shown after inner decoding. Depending on the channel conditions, the signal-to-noise ratio gain can be up to 1.6 dB. The method provides a compatible improvement to DVB-T receivers.
Overexpression of microRNA-223 regulates the ubiquitin ligase FBXW7 in oesophageal squamous cell carcinoma (2011)

Our present study indicates that high expression of miR-223 had a significant adverse impact on the survival of ESCC patients through repression of the function of FBXW7.
A simple test for the interlaminar fracture toughness of composites (1982)

A simple test method for the measurement of delamination resistance is assessed through its application to 11-ply graphite-epoxy laminates whose matrices employ the F185 and 205 resins. The F185 resin has the same base epoxy as the 205, to which liquid and solid elastomers have been added. The critical value of the mixed mode energy release rate, calculated from a closed form equation employing nominal strain measurements from the onset of edge delamination, show that addition of the elastomers to the base epoxy increases interlaminar fracture toughness. Comparison of these results with those of width-tapered double cantilever beam (WTDCB) test data for the two materials shows a similar strain energy release rate, establishing the accuracy of the novel method. Both tests are found to be needed, however, for the quantitative characterization of interlaminar fracture toughness.
Dendritic cells associated with plasmablast survival (1999)

A subset of myeloid dendritic cells is described which is associated with the ability of splenic and lymph node plasmablasts to survive and differentiate into plasma cells. Plasmablast-associated dendritic cells (PDC) are CD11chigh, DEC-205– and unlike conventional dendritic cells do not associate with T cells. The following findings suggest a requirement for PDC if plasmablasts are to differentiate to plasma cells. First, when large numbers of B cells are recruited into antibody responses and plasmablasts outgrow the PDC stroma, only those associated with PDC survive and differentiate into plasma cells. Conversely, if the number of PDC is increased by ligating their CD40, more plasmablasts survive on the expanded PDC stroma and differentiate into plasma cells. Finally, in T cell-deficient mice, the plasma cells that develop atypically in the T zones in response to thymus-independent antigens are associated with ectopic PDC.
Enhanced Neointima Formation and Attachment on the High-Porosity Inner Surface of Modified PTFE Vascular Grafts (1995)

Highly porous PTFE arterial prostheses form endothelium more extensively than the low-porosity grafts in clinical use, but are subject to seroma formation. PTFE vascular grafts were modified to produce a highly porous inner layer (inner layer 60 or 90 microns, outer layer 20 microns). The effect of this modified, composite design on the histology of graft healing was investigated. Twenty-five modified and 25 control grafts, each 4 mm in diameter by 5 cm in length, were implanted into carotid and femoral arteries of dogs. No late seroma formation was observed. After 12 and 18 weeks, the neointima of the grafts was examined by light microscopy and scanning electron microscopy. At 2- and 4-mm distances from the proximal and distal anastomoses, intimal thickness of the control grafts was 238.7 and 96.1 microns, respectively; for the modified grafts it was 236.2 and 202.8 microns at 18 weeks. Thus, the neotinima of modified grafts was thicker than that of control grafts when measured at 4 mm from the anastomoses. Neointimal coverage was less extensive in the control grafts than in modified grafts (26.8 +/- 6.1% vs. 58.8 +/- 13.2%; p < .05). Smooth muscle cells were seen on light-microscopy to penetrate the highly porous inner layer; on scanning electron microscopy, the PTFE fibrils appeared to anchor the neointima of the modified graft. The results suggest that modified PTFE grafts with an inner surface of 60 or 90 microns internodal distance have enhanced formation and anchoring of neointima while remaining impervious to blood.
A novel amorphous silicon doping superlattice device with double switching characteristics for multiple-valued logic applications (1993)

An amorphous silicon doping superlattice device with different period lengths is developed, providing a double switching characteristic that has been demonstrated to yield multiple stable states for multiple-valued logic applications. Unlike those of conventional switching devices, the switching characteristics of the present device are caused by avalanche multiplication and a barrier-lowering effect. A tristate memory cell using this device is proposed and discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
PMT connectors for multi-channel film waveguides (2009)

Intensive research on optical interconnections has attracted considerable attention for high-end router and server applications. A polymer film waveguide is expected to be applied to an optical circuit board in an optical interconnection. The film waveguide requires a conventional connector if it is to be employed as a practical optical circuit board. This paper describes the MT connector used with polymer film waveguide (PMT connector), which is compatible with the MT connector used with optical fiber. This connector can be attached to a film waveguide by passive alignment, and is used to connect waveguides. When the connector was equipped with an epoxy resin film waveguide, the insertion and connection losses were less than 1.4 and 0.5 dB, respectively. These losses are sufficiently small to meet the basic requirement for optical circuit boards, so we were able to fabricate a flexible optical circuit board with PMT connectors. This paper also describes the application of a film waveguide with PMT connectors to an optical front plane system.
Highly Efficient Dynamic Kinetic Resolution of Azlactones by Urea‐Based Bifunctional Organocatalysts (2005)

Novel tasks for a venerable molecule: Bifunctional organocatalysts of the type shown, with a quasi Lewis acidic urea or thiourea unit and a Brønsted basic amine functionality, effect the dynamic kinetic resolution of azlactones with high enantioselectivity. N-Benzoyl amino acid esters were obtained with up to 91 % ee in high yields from racemic azlactones.
Neural network design based on decomposition of decision space (2003)

The networks considered are multi-layer perceptrons. The method developed by the author describes how points in a classification volume could be separated by using Voronoi polygons and then removing the separation boundaries between polygons of the same type. Such an operation leaves behind a boundary that is necessary to separate the different types of regions. Unfortunately, the separation surface (decision surface) itself provides sufficient information to associate the surface with the network.
Perspectives on New Synthetic Curcumin Analogs and their Potential Anticancer Properties (2013)

Curcumin is the active component of dried rhizome of Curcuma longa, a perennial herb belonging to ginger family, cultivated extensively in south and southeastern tropical Asia. It is widely consumed in the Indian subcontinent, south Asia and Japan in traditional food recipes. Extensive research over last few decades has shown that curcumin is a potent anti-inflammatory agent with powerful therapeutic potential against a variety of cancers. It suppresses proliferation and metastasis of human tumors through regulation of various transcription factors, growth factors, inflammatory cytokines, protein kinases and other enzymes. It induces apoptotic cell death and also inhibits proliferation of cancer cells by cell cycle arrest. Pharmacokinetic data has shown that curcumin undergoes rapid metabolism leading to glucuronidation and sulfation in the liver and excretion in the feces, which accounts for its poor systemic bioavailability. The compound has, therefore, been formulated and administered using different drug delivery systems such as liposomes, micelles, polysaccharides, phospholipid complexes and nanoparticles that can overcome the limitation of bioavailability to some extent. Attempts to avoid rapid metabolism of curcumin until now have been met with limited success. This has prompted researchers to look for new synthetic curcumin analogs in order to overcome the drawbacks of limited bioavailability and rapid metabolism, and gain efficacy with reduced toxicity. In this review we provide a summarized account of novel synthetic curcumin formulations and analogs, and the recent progress in the field of cancer prevention and treatment.
The NH2-terminal proregion of peptidylglycine alpha-amidating monooxygenase facilitates the secretion of soluble proteins. (1995)

A highly conserved ten amino acid proregion separates the peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain of the bifunctional peptidylglycine alpha-amidating monooxygenase (PAM) protein from the NH2-terminal signal peptide; propeptides with amino acid sequences similar to the PAM proregion have been identified in other secreted proteins. In AtT-20 cells, but not in human embryonic kidney (hEK)-293 cells, an endogenous endoprotease acting at a site distal to the trans-Golgi network efficiently removes the propeptide from stably transfected monofunctional PHM (PHMs). We constructed a mutant PHM protein (delta ProPHMs) in which the proregion was deleted and the signal peptide joined directly to the monooxygenase domain. Newly synthesized, enzymatically active delta ProPHMs was secreted from both AtT-20 cells and hEK-293 cells more slowly than PHMs. In endocrine cells, the proregion was not required for storage in regulated secretory granules. We transferred the PAM proregion to prohormone convertase 2 (PC2), another soluble constituent of secretory granules, to determine whether the effect of the proregion were transferrable. In both AtT-20 cells and hEK-293 cells, the PAM/PC2 fusion molecule was able to exit the endoplasmic reticulum more rapidly than PC2.
<title>Embedding the 2D interaction metaphor in a real 3D virtual environment</title> (1995)

Recent advances in both rendering algorithms and hardware has brought virtual reality to the threshold of being able to model realistically complex environments, e.g., the mockup of a large structure. As impressive as these advances have been there is still little that a user can do within a VR system other than look--and react. If VR is to be usable in a design setting users will need to be able to interact, to control and modify their virtual environments using virtual tools inside that environment. In this paper we describe a realistic virtual computer/personal digital assistant that we have built. To the user this virtual computer appears as a hand held flat panel display. Input can be provided to this virtual computer using a virtual finger or stylus to `touch' the screen. We migrate applications developed for a flat screen environment into the virtual environment without modifying the application code. A major strength of this approach is that we meld the naturally 3D interaction metaphor of a hand held virtual tool with the software support provided by some 2D user interface toolkits. Our approach has provided us great flexibility in both designing and implementing user interface components for VR environments, and it has enabled us to represent the familiar flat screen human computer interaction metaphor within the VR context. We will describe some applications which made use of our capability.
Delaware’s My Healthy Community Data Platform: (2021)

“Delawareans need to have access to usable, meaningful, timely, and high-quality data about the health of the communities in which they live,”1 so that data-driven evidence-based decisions result in community-focused solutions to affect positive change. This statement is the vision of the My Healthy Community (MHC) data portal,2 which serves as Delaware’s population health platform. The MHC platform shares data on a myriad of population health areas such as social vulnerability, community characteristics, the environment (e.g., public and private drinking water, air quality), chronic diseases, mental health and substance use, healthy lifestyles, maternal and child health, health care utilization, and infectious diseases. MHC continues to expand in both data and functionality to serve as a tool to track the outcomes of implementing data-driven population health interventions and utilizing technology to monitor and evaluate the effectiveness of interventions. Shortly after the coronavirus disease 2019 (COVID-19) pandemic took a foot hold in the United States, in April of 2020, only 11 months after MHC was publicly launched, the site also became Delaware’s coronavirus disease 2019 (COVID-19) dashboard, presenting statistics on COVID-19 cases, hospitalization, emergency department visits, testing, deaths, vaccination, contact tracing, and in-person contagious school cases.

MHC’s origins lie in the intersection between public health informatics and epidemiology. Visionaries within Delaware’s public health agency paved the way to create MHC with the support of DPH leadership and the perseverance and dedication of a small team of public health professionals. With their own unique lenses, one of public informatics and the other of epidemiology, the team’s efforts materialized into a tool that continues to evolve and respond to Delaware’s changing needs.
Design and evaluation of parallel pipelined join algorithms (1987)

The join operation is the most costly operation in relational database management systems. Distributed and parallel processing can effectively speed up the join operation. In this paper, we describe a number of highly parallel and pipelined multiprocessor join algorithms using sort-merge and hashing techniques. Among them, two algorithms are parallel and pipelined versions of traditional sort-merge join methods, two algorithms use both hashing and sort-merge techniques, and another two are variations of the hybrid hash join algorithms. The performance of those algorithms is evaluated analytically against a generic database machine architecture. The methodology used in the design and evaluation of these algorithms is also discussed.
Transformation of 4‐(1‐dimethylaminoethylidene)‐2‐phenyl‐5(4<i>H</i>)‐oxazolone into methyl 2‐benzoylamino‐3‐oxobutanoate. The synthesis of 1‐substituted 4‐benzoylamino‐3‐methyl‐5(2<i>H</i>)‐pyrazolones (1998)

Abstract Methyl 2‐benzoylamino‐3‐oxobutanoate ( 3 ) was prepared from hippuric acid (1) which was converted with N,N‐ dimethylacetamide and phosphorus oxychloride into 4‐(1‐dimethylaminoethylidene)‐2‐phenyl‐5(4 H )‐oxazolone ( 2 ) followed by hydrolysis with hydrochloric acid in methanol. Compound 3 was treated with hydrazines 4 to give 4‐benzoylamino‐3‐methyl‐1 H ‐pyrazol‐5(2 H )‐one ( 6a ) and its 1‐substituted derivatives 6b‐j . The corresponding hydrazones 5f, i, j were isolated as intermediates.
Multiple functions of Ldb1 required for β-globin activation during erythroid differentiation (2010)

Ldb1 and erythroid partners SCL, GATA-1, and LMO2 form a complex that is required to establish spatial proximity between the β-globin locus control region and gene and for transcription activation during erythroid differentiation. Here we show that Ldb1 controls gene expression at multiple levels. Ldb1 stabilizes its erythroid complex partners on β-globin chromatin, even though it is not one of the DNA-binding components. In addition, Ldb1 is necessary for enrichment of key transcriptional components in the locus, including P-TEFb, which phosphorylates Ser2 of the RNA polymerase C-terminal domain for efficient elongation. Furthermore, reduction of Ldb1 results in the inability of the locus to migrate away from the nuclear periphery, which is necessary to achieve robust transcription of β-globin in nuclear transcription factories. Ldb1 contributes these critical functions at both embryonic and adult stages of globin gene expression. These results implicate Ldb1 as a factor that facilitates nuclear relocation for transcription activation.