gebhart/patrepeval huggingface dataset:
HEPATITIS C VIRUS AND ORGAN TRANSPLANTATION (1996)

Hepatitis C virus (HCV) is both the leading cause of cirrhosis and hepatic failure leading to liver transplantation and a cause of chronic hepatitis in approximately 10% of all transplant recipients. Beginning 5-10 years or more posttransplant, HCV causes progressive liver disease in a significant fraction of infected individuals and contributes to an increased incidence of opportunistic infection and hepatocellular carcinoma. The existence of multiple genotypes of HCV with differing biologic behaviors and the generation of antigenic diversity of the virus (quasispecies) during the course of infection, limit the capacity of the immune system to generate protective immunity. Antiviral therapy with interferon-alpha is effective in only a minority of transplant patients, and since allografts from HCV infected donors are quite efficient in transmitting the virus, great attention is paid to the appropriate use of organs from HCV-positive donors. At present, these organs should be particularly targeted for patients in emergent need of lifesaving heart, liver, or lung transplants. Issues requiring further investigation include the impact of viral superinfection on HCV-infected recipients of organs from HCV-infected donors and the use of such organs in seronegative patients who are older, diabetic, or highly sensitized, for whom quality of life issues may outweigh the long-term impact of HCV infection.
The Programmable Remapper: Clinical Applications for Patients with Field Defects (1989)

NASA, Johnson Space Center is developing an electronic image remapper which will warp an image from one coordinate system onto another with great flexibility and speed. The Programmable Remapper will transform images at conventional video frame rate. The Remapper was designed to be used in conjunction with an optical correlator to enhance object recognition through “real time” Fourier analysis. We are investigating an additional potential application for the Remapper as a low-vision aid. In diseases which result in obvious field defects such as age-related maculopathy (ARM) or retinitis pigmentosa (RP), the Remapper can be used to redistribute onto the still-functioning retina the image information that would otherwise be lost due to the associated field defect. Compared with eccentric viewing, this process makes use of the acuity of a larger area of the retina. We envision the future aid to consist of a portable spectacle-mounted display with miniaturized camera input and the Remapper. The patient will view the remapped world on this display. Patients may require training with feedback as to eye and scotoma position in order to use the Remapper most effectively. The Remapper might be reduced in cost, weight, and size to the point of being a feasible low-vision prosthesis as a result of development required by military, space, and industrial utilization. In order to demonstrate how such an aid may work, we have generated static images on an image processor which have undergone radial-only remapping; i.e., image points are slid along radii, with their azimuths unchanged. The remapping process and the application to low vision along with static images are presented in this paper.
Solid-state Over-current Protection for Industrial DC Distribution Systems (2006)

We describe a concept for circuit protection and fault current limitation in DC power systems based on the use of solid-state power switches. The approach could be useful in the increasingly widespread application of DC power distribution networks. During normal operation the power switch is always on. During faults, the gate of the solid-state switch is pulse modulated to prevent the circuit current from exceeding a predetermined limit. This lowers the demand on the solid-state switches to withstand and interrupt the fault current and thus makes it possible to use commercially available solid-state switches. The described architecture enables loads in non-faulted parts of the system to ride through the fault current-limiting process unperturbed. Simulations demonstrate the effectiveness of the strategy and a low power prototype validated the simulation model. The interactions between the protection switches and the upstream converters were studied, and the design equations for the circuit parameters are derived. Simulations and experiments demonstrate that the protection circuit provides a fast and potentially maintenance-free protection solution for high power-density DC systems. This technology is especially significant for applications related to spacecraft and shipboard DC power systems.
Blind multiuser identification and detection in CDMA systems (2002)

Multiuser detection in code division multiple access systems usually requires either knowledge of the transmitted signature sequences and channel state information or use of a known training sequence for adaptation. We develop a scheme that can be employed for the joint adaptive blind multiuser identification and detection in asynchronous CDMA systems. This scheme relies on a multiuser Viterbi algorithm that incorporates an adaptive estimation of the overall channel impulse responses, given by the convolution of the signature sequences of the users and corresponding physical channels impulse responses. Once the overall channel responses are estimated, the blind multiuser detection algorithm performs like the maximum-likelihood sequence estimator. Results are provided to illustrate the convergence of the blind multiuser approach, near-far resistance and sensitivity to the algorithm initialization.
Evidence for redundancy in propeptide/prohormone convertase activities in processing proglucagon: an antisense study. (1996)

To further examine the physiological roles of the neuroendocrine prohormone convertases (PCs) in proglucagon processing, alpha TC1-6 cells were transiently transfected with PC1/3 and PC2 expression vectors containing either antisense or sense encoding cDNAs. PC1/3- and PC2-directed RIAs were used to determine that the PC1/3 antisense transfections lowered endogenous levels of PC1/3 by 40 +/- 7.9% but did not alter the levels of PC2. The PC2 antisense transfections decreased the endogenous levels of PC2 by 91 +/- 11.7% without affecting the levels of PC1/3. To quantitate the levels of proglucagon and proglucagon-derived products, transfected cells were metabolically labeled with [3H]tryptophan, and extracts were chromatographed by reversed-phase HPLC. Recovered peptides were then subjected to peptide mapping analyses, allowing precise quantification of 3H-radioactivity incorporated into proglucagon and its cleavage products. Product-precursor ratios were determined, and percent change in the proportion of products generated in antisense-transfected vs. sense-transfected cells was calculated. The decrease in PC1/3 after antisense treatment significantly reduced the amounts of glicentin produced and partially reduced the levels of all other proglucagon cleavage products. PC2 antisense treatment significantly reduced the levels of glicentin and 9K glucagon generated but had no significant effect on the remainder of the proglucagon-derived peptides. These results suggest the existence of redundant mechanisms that ensure the production of each of the intermediate and product peptides derived from proglucagon. PC1/3 is potentially an important enzyme in the processing of most proglucagon-derived peptides, whereas PC2-processing activity appears to predominate at only two of the four potential cleavage sites.
Travaux d'entretien en forêt par des procédés mécaniques (1950)

International audience
Beyond semi-supervised tracking: Tracking should be as simple as detection, but not simpler than recognition (2009)

We present a multiple classifier system for model-free tracking. The tasks of detection (finding the object of interest), recognition (distinguishing similar objects in a scene), and tracking (retrieving the object to be tracked) are split into separate classifiers in the spirit of simplifying each classification task. The supervised and semi-supervised classifiers are carefully trained on-line in order to increase adaptivity while limiting accumulation of errors, i.e. drifting. In the experiments, we demonstrate real-time tracking on several challenging sequences, including multi-object tracking of faces, humans, and other objects. We outperform other on-line tracking methods especially in case of occlusions and presence of similar objects.
ANALYSIS OF STERYL GLUCOSIDES IN FOODS AND DIETARY SUPPLEMENTS BY SOLID‐PHASE EXTRACTION AND GAS CHROMATOGRAPHY (2005)

ABSTRACT A method to quantify β‐sitosterol (BSS) and β‐sitosteryl glucoside (BSSG) in dietary supplements containing added BSS and BSSG was developed and also validated for the analysis of naturally occurring free and esterified sterols and steryl glucosides in foods. Steryl glucosides were extracted with hexane‐diethyl ether (1 : 1, v/v) after the alkaline saponification of a powdered supplement or of total lipid extracts of whole wheat flour, granola bars, soybeans, flaxseed, dried figs, peanut butter, lyophilized mixed vegetables, almonds, pine nuts and a diet homogenate. An oil‐based supplement was analyzed directly. Steryl glucosides were isolated by solid‐phase extraction, derivatized and quantified as trimethylsilyl ethers using capillary gas chromatography (GC) with a 5% diphenyl−95% dimethylpolysiloxane column. Recovery studies using a commercially available mixed steryl glucoside standard and gas chromatography‐mass spectrometry (GC‐MS) analyses validated the method. Approximately 2–36 mg/100 g (9–37%) of total sitosterol, campesterol and stigmasterol in the foods was contributed by the glucosides.
Organic light-emitting diode (OLED) (2008)

Organic? Organic in the sense that they utilise a carbon-hydrogen-based structure, like us, versus a silicon-based structure for the LEDs that we've been familiar with over the last several decades. This organic film can be deposited in thin layers on many types of materials in a process that is more like printing on paper as opposed to the complicated process for manufacturing standard LEDs and integrated circuits.
High temperature soft magnetic materials: FeCo alloys and composites (2000)

We have systematically investigated the microstructural effects including grain size, precipitation, and structural order parameter on the high temperature magnetic and mechanical properties of FeCo-based commercial alloys. At high temperatures the equilibrium nonmagnetic precipitates significantly deteriorate the soft magnetic properties. Poor mechanical properties are mainly due to the nature of the ordered structure of FeCo alloys. Based on this understanding we have designed new magnetic composites by reinforcing FeCo alloys with high strength fibers. The magnetic and mechanical properties can thus be improved independently through optimizing the magnetic matrix and fiber network, respectively. These new magnetic composites show excellent soft magnetic and mechanical properties. In particularly, negligible creep has been observed at 600/spl deg/C.
Build an Intelligent Online Marketing System: An Overview (2019)

With the rapid growth of Internet users, online marketing has become one of the most effective channels to reach new customers. In this paper, an intelligent online marketing system architecture is presented to better facilitate online marketing. We first provide an overview of the customer conversion challenges faced when marketing online. Then, we outline an architectural design of the productionized intelligent marketing system, which consists of tracking, metrics, attribution, bidding, keyword generation and many other core functionalities, and discuss the interactions between these components. Based on the internal results, this design can help advertisers reduce operational costs, increase operational efficiency, optimize return on investment, and increase customer engagement. We hope that the proposed architecture can be beneficial to software engineers, marketers, and researchers, and it has the potential to motivate the research on online marketing system design and accelerate the advent of fast, smart, and scalable marketing systems.
Congratulatory Address (1946)

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Segment Routing: A Comprehensive Survey of Research Activities, Standardization Efforts, and Implementation Results (2020)

Fixed and mobile telecom operators, enterprise network operators and cloud providers strive to face the challenging demands coming from the evolution of IP networks (e.g., huge bandwidth requirements, integration of billions of devices and millions of services in the cloud). Proposed in the early 2010s, Segment Routing (SR) architecture helps face these challenging demands, and it is currently being adopted and deployed. SR architecture is based on the concept of source routing and has interesting scalability properties, as it dramatically reduces the amount of state information to be configured in the core nodes to support complex services. SR architecture was first implemented with the MPLS dataplane and then, quite recently, with the IPv6 dataplane (SRv6). IPv6 SR architecture (SRv6) has been extended from the simple steering of packets across nodes to a general network programming approach, making it very suitable for use cases such as Service Function Chaining and Network Function Virtualization. In this article, we present a tutorial and a comprehensive survey on SR technology, analyzing standardization efforts, patents, research activities and implementation results. We start with an introduction on the motivations for Segment Routing and an overview of its evolution and standardization. Then, we provide a tutorial on Segment Routing technology, with a focus on the novel SRv6 solution. We discuss the standardization efforts and the patents providing details on the most important documents and mentioning other ongoing activities. We then thoroughly analyze research activities according to a taxonomy. We have identified 8 main categories during our analysis of the current state of play: Monitoring, Traffic Engineering, Failure Recovery, Centrally Controlled Architectures, Path Encoding, Network Programming, Performance Evaluation and Miscellaneous. We report the current status of SR deployments in production networks and of SR implementations (including several open source projects). Finally, we report our experience from this survey work and we identify a set of future research directions related to Segment Routing.
Robust OFDM Timing Synchronisation in Multipath Channels (2008)

This paper addresses pre-FFT synchronisation for orthogonal frequency division multiplex (OFDM) under varying multipath conditions. To ensure the most efficient data transmission possible, there should be no constraints on how much of the cyclic prefix (CP) is occupied by intersymbol interference (ISI). Here a solution for timing synchronisation is proposed, that is, robust even when the strongest multipath components are delayed relative to the first arriving paths. In this situation, existing methods perform poorly, whereas the solution proposed uses the derivative of the correlation function and is less sensitive to the channel impulse response. In this paper, synchronisation of a DVB single-frequency network is investigated. A refinement is proposed that uses heuristic rules based on the maxima of the correlation and derivative functions to further reduce the estimate variance. The technique has relevance to broadcast, OFDMA, and WLAN applications, and simulations are presented which compare the method with existing approaches.
Synthesis and thermal expansion properties of ZrO2/ZrW2O8 composites (2004)

In this work, a ceramic composite of ZrW2O8 and ZrO2 was synthesized, in order to investigate the possibility of compensating the positive thermal expansion of ZrO2 with the negative thermal expansion (NTE) compound ZrW2O8, tailoring the thermal expansion of these composites. The NTE material was mixed with varying amounts of ZrO2. The thermal expansion coefficients of this series of composites decrease with increasing amounts of ZrW2O8. Nevertheless, a negative deviation from the values expected by the rule of mixtures was found to be most pronounced in the middle of the compositional region. © 2004 Elsevier Ltd. All rights reserved.
DISTURBANCES OF SENSATION IN CHILDREN WITH HEMIPLEGIA (1954)

Major attention has properly been directed at the motor handicap in hemiplegia, but the frequent coexistence of mental defect and convulsions is also well known. The possibilities of significant sensory impairment and of visual defects, however, while well known as a feature of cerebral vascular accidents among adults, have received scant attention in connection with the long-term management of hemiplegia in childhood and young adult life. The standard pediatric, orthopedic, and neurological textbooks largely ignore the subject, which has received only infrequent and relatively recent mention in medical periodicals. Bender 1 mentions its frequency among adult hemiplegics, especially if tested by the extinction method, and a brief preliminary report of our study has already been presented. 2 Detailed testing of sensation and visual fields of hemiplegic children presents technical difficulties, which have doubtless in part accounted for inattention to such features in the past. The difficulties are not insurmountable, however,
4 GHz miniaturized low noise dielectric resonator stabilized oscillator (2003)

A 4-GHz miniaturized oscillator has been developed. It consists of a 17-GHz (17.84-GHz) DRO (dielectric resonator oscillator) and divide-by-four analog frequency divider. The 17-GHz DRO uses a HEMT (high-electron-mobility transistor) with series feedback. The frequency divider built was based on the concept of an injection locking oscillator using a bipolar transistor. The circuit provides an excellent phase noise of -120 dBc/Hz at 100-kHz offset from the carrier and a good temperature stability of +or-150 kHz over the temperature range of -20 degrees C to +80 degrees C. The circuit size is about 1/8 that of conventional 4.46-GHz DRO. The DRO and frequency divide combination provides advantages of small volume and ease of design.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells (2001)

T-cell-receptor (TCR)-mediated LAT (linker for activation of T cells) phosphorylation is critical for the membrane recruitment of signalling complexes required for T-cell activation. Although tyrosine phosphorylation of LAT is required for recruitment and activation of signalling proteins, the molecular mechanism associated with this event is unclear. In the present study we reconstituted the LAT signalling pathway by demonstrating that a direct tyrosine phosphorylation of LAT with activated protein-tyrosine kinase Zap70 is necessary and sufficient for the association and activation of signalling proteins. Zap-70 efficiently phosphorylates LAT on tyrosine residues at positions 226, 191, 171, 132 and 127. By substituting these tyrosine residues in LAT with phenylalanine and by utilizing phosphorylated peptides derived from these sites, we mapped the tyrosine residues in LAT required for the direct interaction and activation of Vav, p85/p110α and phospholipase Cγ1 (PLCγ1). Our results indicate that Tyr226 and Tyr191 are required for Vav binding, whereas Tyr171 and Tyr132 are necessary for association and activation of phosphoinositide 3-kinase activity and PLCγ1 respectively. Furthermore, by expression of LAT mutants in LAT-deficient T cells, we demonstrate that Tyr191 and Tyr171 are required for T-cell activation and Tyr132 is required for the activation of PLCγ1 and Ras signalling pathways.
Estimation of recombination frequencies and construction of RFLP linkage maps in plants from crosses between heterozygous parents. (1990)

The construction of a restriction fragment length polymorphism (RFLP) linkage map is based on the estimation of recombination frequencies between genetic loci and on the determination of the linear order of loci in linkage groups. RFLP loci can be identified as segregations of singular or allelic DNA-restriction fragments. From crosses between heterozygous individuals several allele (fragment) configurations are possible, and this leads to a set of formulas for the evaluation of p, the recombination frequency between two loci. Tables and figures are presented illustrating a general outline of gene mapping using heterozygous populations. The method encompasses as special cases the mapping of loci from segregating populations of pure lines. Formulas for deriving the recombination frequencies and information functions are given for different fragment configurations. Information functions derived for relevant configurations are also compared. A procedure for map construction is presented, as it has been applied to RFLP mapping in an allogamous crop.
The contribution of social anthropology to social work practice (1952)

(1952). The contribution of social anthropology to social work practice. Australian Journal of Social Work: Vol. 6, No. 3, pp. 41-53.
An integrated modular avionics development environment (2009)

The ARINC 653 standard has taken a leading role within the aeronautical industry in the development of safety-critical systems based on the Integrated Modular Avionics (IMA) concept. One of the main promises of IMA is cost saving in reduced development, integration and verification and validation effort. To exploit the full potential of cost savings, it is necessary to establish an effective way to prototype, develop, test and analyse on-board applications without having access to the final IMA target platform for all engineers. Target platforms are usually extremely expensive considering hardware and software prices as well as training costs. This paper describes the architecture of the Integrated Modular Avionics Development Environment (IMADE) that is based on Linux and the ARINC 653 simulator Simulated IMA (SIMA) that was developed by Skysoft Portugal, 2007-2009.
Effects of rare earth metals on electrical conductivity and mechanical properties of commercial purity aluminium (1994)

The effects of the addition of rare earth metals on the electrical conductivity and mechanical properties of commercial purity aluminium have been investigated both in the laboratory and in industrial trials. The electrical conductivity of commercial purity aluminium is increased by about 1% on the international annealed copper standard by the addition of lanthanum, and both its tensile strength and elongation are improved considerably by the addition of cerium. Investigation of the microstructure of the alloys containing rare earth metals shows that the apparent improvement in the electrical conductivity of commercial purity aluminium is caused by a decrease in the solid solubility of impurities in the aluminium.MST/2032
Unexpected drug effects on autonomic function during myocardial ischaemia (1993)

Journal Article Unexpected drug effects on autonomic function during myocardial ischaemia Get access Anthony M Dart, Anthony M Dart Baker Medical Research Institute, Commercial Road, Prahan, Victoria 3181, Australia: A M Dart, X-J Du. Correspondence to Dr Dart. Search for other works by this author on: Oxford Academic PubMed Google Scholar Xiao-Jun Du Xiao-Jun Du Baker Medical Research Institute, Commercial Road, Prahan, Victoria 3181, Australia: A M Dart, X-J Du. Search for other works by this author on: Oxford Academic PubMed Google Scholar Cardiovascular Research, Volume 27, Issue 6, June 1993, Pages 906–914, https://doi.org/10.1093/cvr/27.6.906 Published: 01 June 1993 Article history Accepted: 15 January 1993 Published: 01 June 1993