gebhart/patrepeval huggingface dataset:
The Nomenclature of Polyoxometalates:  How To Connect a Name and a Structure (1998)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Nomenclature of Polyoxometalates: How To Connect a Name and a Structure†Yves P. JeanninView Author Information Laboratoire de Chimie des Métaux de Transition, URA-CNRS 419, Université Pierre et Marie Curie, 4, Place Jussieu, 75252 Paris cedex 05, France Cite this: Chem. Rev. 1998, 98, 1, 51–76Publication Date (Web):January 21, 1998Publication History Received11 April 1997Revised29 July 1997Published online21 January 1998Published inissue 1 February 1998https://doi.org/10.1021/cr960397iCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views2625Altmetric-Citations151LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (472 KB) Get e-AlertscloseSUBJECTS:Chemical structure,Ligands,Metals,Oxygen,Tungsten Get e-Alerts
Incremental computation of planar maps (1989)

A planar map is a figure formed by a set of intersecting lines and curves. Such an object captures both the geometrical and the topological information implicitly defined by the data. In the context of 2D drawing it provides a new interaction paradigm, map sketching, for editing graphic shapes.To build a planar map, one must compute curve intersections and deduce from them the map they define. The computed topology must be consistent with the underlying geometry. Robustness of geometric computations is a key issue in this process. We present a robust solution to Bézier curve intersection that uses exact forward differencing and bounded rational arithmetic. Then, we describe data structure and algorithms to support incremental insertion of Bézier curves in a planar map. A prototype illustration tool using this method is also discussed.
CAPITAL IVHS OPERATIONAL TEST (1994)

The CAPITAL IVHS Operational Test program is a complete end-to- end test from the collection and processing of wide area surveillance data to the dissemination of traffic data to remote users and in-vehicle equipment. The architecture to support this Operational Test makes extensive use of the in-place cellular infrastructure for both wide area surveillance and communications. ERA's equipment will be co-located at selected Bell Atlantic Mobile (BAM) towers to collect cellular phone usage statistics and geolocate phones on designated roadways. The sections of roadway currently designated are in Montgomery County, Maryland at I-270, from I-495 to Montrose Road, I-495 west, from I-270 to I-66, from I-495 to Rt. 123 and selected arterials.
Biomechanical evaluation of bone‐porous material interfaces (1973)

Abstract An investigation was undertaken to correlate mechanical strengths of various bone‐porous material interfaces with the type and degree of osseous ingrowth. Intracortical cylinders of porous and nonporous metals, ceramics, polymers, and carbon were implanted into canine long bones and examined at 3, 6, and 12 weeks. Reflected and transmitted light microscopy were used to study bone ingrowth. Electron microprobe analysis and tetracycline labelling were used to characterize the degree of mineralization of the ingrowth. Shear strengths of bone‐porous material interfaces were measured on cylinders forced out in compression. Microhardness traverses were made across the interfaces. Readily identifiable bone was shown by histology in many porous specimens. Mineralization was found to various depths in all the porous specimens. The porous metals displayed the greatest interfacial shear strengths and hardnesses, with values from one‐ to two‐thirds that of cortical bone. Changes occurred in the ingrowth region, a bone‐metal composite, which suggest a reduction of elastic mismatch.
Plasma Electron Capture Dissociation for the Characterization of Large Proteins by Top Down Mass Spectrometry (2003)

For the backbone dissociation of large (29 kDa) multiply charged protein ions in the gas phase by electron capture, the main experimental challenges are juxtaposition of the electron and ion for efficient capture, dissociation of tertiary noncovalent bonds that prevent product separation, and minimization of secondary electron capture that destroys larger product ions. A simple alternative methodology is described in which electrons (0.03-100 microA, 0.1-15 eV) are first impinged on a gas pulse in the ion cell of a Fourier transform mass spectrometer, followed by ion beam introduction. For carbonic anhydrase, the resulting plasma conditions produce 87% efficiency for electron capture; a single spectrum yields 512 product ions of 237 different masses from cleavage of 183 of the 258 interresidue bonds, while two spectra cleave 197 of these bonds. The problem of secondary dissociation of product ions is reduced by plasma conditions in which product ions are formed near electrons whose velocities are unfavorable and whose capture cross sections no longer have a square dependence on charge. One plasma ECD spectrum of ubiquitin provides its sequence de novo except for two residue pairs. ECD of casein identifies 126 of 208 interresidue cleavages, providing direct and specific characterization of all its 26 Ser/Thr/Tyr phosphorylation sites.
Detecting structural changes in object oriented software systems (2005)

It is an increasingly accepted fact that software development is a non-linear activity with inherently feedback driven processes. In such a development environment, however, it is important that major structural changes in the design and/or architecture of a software system under development are introduced with care and documented accordingly. In order to give developers appropriate tools that can identify such changes, we need to have a good understanding how software systems evolve over time so that evolutionary anomalies can be automatically detected. In this paper, we present recurring high-level structural and evolutionary patterns that we have observed in a number of public-domain object-oriented software systems and define a simple predictive model that can aid developers in detecting structural changes and as a consequence, improve the underlying development processes.
Compounds Which Serve as the Sole Source of Carbon or Nitrogen for <i>Salmonella typhimurium</i> LT-2 (1969)

About 600 compounds were screened as possible carbon or nitrogen sources for Salmonella typhimurium LT-2. About 100 utilizable compounds were found.
The graphical determination of <i>Km</i> and <i>Ki</i> (1972)

The principle of Dixon (1965) has been extended to give rapid graphical methods for determining enzyme constants for substrates (Km) and inhibitors (Ki). It does away with the sometimes questionable assumption that the amounts of substrate or inhibitor bound by the enzyme are negligible in comparison with the total amount added, and is therefore valid even for cases of high affinity, where the usual methods fail. Besides doing away with the need for calculation, it enables the concentrations of the various components of the system to be read off directly for any point of the velocity curve.
Quantitative Immunohistochemical Determination of Cathepsin D Levels in Prostatic Carcinoma Biopsies:<i>Correlation with Tumor Grade, Stage, PSA Level, and DNA Ploidy Status</i> (1995)

National screening programs resulting in an increased detection rate of prostatic adenocarcinoma have prompted the search for new methods of predicting disease outcome that can be applied to the initial narrow bore needle biopsy specimens. Cathepsin D, a lysosomal aspartyl protease and autocrine mitogen, has been studied in a wide variety of human neoplasms as an invasion and metastasis marker. Prostatic carcinoma needle biopsy tumor cell cathepsin D content was measured in 61 men using a semiquantitative image analysis assisted immunohistochemical procedure. Results were compared with preoperative serum prostatic specific antigen levels, tumor grade, DNA ploidy status, pathologic stage after radical prostatectomy and disease recurrence during a median 2.6 year follow-up. Biopsy cathepsin D levels significantly correlated with tumor grade (P = .022) and DNA ploidy status (P = .028) by logistic regression analysis. Post-prostatectomy pathologic stage and disease recurrence did not correlate with tumor cathepsin D levels. Final prostatectomy grade and DNA ploidy status independently predicted metastasis and post-operative disease recurrence (P < .001). Although this study did not find independent prognostic status for cathepsin D in prostate cancer, the correlation with tumor grade and DNA ploidy status is noteworthy and the inter-relationship of outcome variables may prove of interest and warrant further evaluation of this potential predictor or CO-predictor of disease outcome.
Asymmetric behavior of archaeal prolyl‐tRNA synthetase (2005)

Archaeal prolyl-tRNA synthetases differ from their bacterial counterparts: they contain an additional domain (about 70 amino acids) appended to the carboxy-terminus and lack an editing domain inserted into the class II catalytic core. Biochemical and structural approaches have generated a wealth of information on amino acid and tRNA specificities for both types of ProRSs, but have left a number of aspects unexplored. We report here that the carboxy-terminal domain of Methanocaldococcus jannaschii ProRS is not involved in tRNA binding since its deletion only mildly affects the kinetic parameters for the enzyme. We also demonstrate that M. jannaschii ProRS is a homodimeric enzyme that is functionally asymmetric; only one of the two active sites at a time is able to form prolyl-adenylate, and only one tRNA molecule binds per dimer. Together with previous reports our results show that asymmetry might be a general feature of the aminoacylation reaction catalyzed by dimeric aminoacyl-tRNA synthetases from both classes.
FIELD TESTS OF A COPPER-BASED FUNGICIDE AS A BIRD REPELLENT RICE SEED TREATMENT (1994)

In east Texas, bird damage to sprouting rice was reduced in two of seven study plots when rice seed was treated with the fungicide Kocide® SD at the maximum label rate (8 fluid oz/100 lb seed). Foraging rates of male redwinged blackbirds (Agelaius phoeniceus) in treated plots were lower P = 0.02) than were those in control plots. We suspect that the copper in Kocide SD produces physiological effects that suppress feeding activity that results in reduced losses in some cases. Because it is registered for use on rice and is relatively inexpensive, Kocide SD may be a useful component of some bird damage reduction strategies.
<i>N</i>,<i>N</i>′-Dimethyl-1,4-dithiine-1,2:4,5-tetracarboximide and<i>N</i>,<i>N</i>′-dimethyl-1,4-diselenine-1,2:4,5-tetracarboximide (2000)

The title compounds of sulfur, C10H6N2O4S2, (I), and selenium, C10H6N2O4Se2, (II), are isomorphous. The crystallographically centrosymmetric mol­ecules are planar. The bond distances and angles, except for those involving the S and Se atoms, are comparable. The mol­ecules are disposed in layers parallel to the bc plane. The molecular axes differ by 75° for (I) and by 80° for (II) from one layer to the next.
Simian varicella virus gene 28 and 29 promoters share a common upstream stimulatory factor-binding site and are induced by IE62 transactivation (2006)

Simian varicella virus (SVV) is a neurotropic alphaherpesvirus that causes a natural, varicella-like disease in non-human primates. After resolution of the primary disease, SVV, like its human counterpart, varicella-zoster virus (VZV), establishes latent infection in the neural ganglia of the host. In this study, gene expression of SVV open reading frames (ORFs) 28 and 29, which encode the viral DNA polymerase and DNA-binding protein, respectively, was characterized during lytic infection of Vero cells. The results indicate that the intergenic region controlling gene 28 and 29 expression includes overlapping, divergent promoters. The ORF 28 and 29 promoters are active in SVV-infected Vero cells, but not in uninfected cells. The SVV immediate-early gene 62 (IE62) product transactivates ORF 28 and 29 expression, and a cellular upstream stimulatory factor-binding site is important for efficient IE62 induction of genes 28 and 29. DNA sequence analysis of the 185 bp intergenic region identified putative cellular transcription factor-binding sites. Transcriptional analysis mapped ORF 28 and 29 RNA start sites. A recombinant SVV was employed to demonstrate that the ORF 29 promoter can express a heterologous gene (green fluorescent protein) when inserted into a novel site (the ORF 12/13 intergenic region) within the SVV genome. The findings demonstrate similarities between SVV and VZV ORF 28/29 expression and indicate that the simian varicella model may be useful to investigate the differential regulation of viral genes during lytic and latent infection.
Soy Protein Isolate As Fluid Loss Additive in Bentonite–Water-Based Drilling Fluids (2015)

Wellbore instability and formation collapse caused by lost circulation are vital issues during well excavation in the oil industry. This study reports the novel utilization of soy protein isolate (SPI) as fluid loss additive in bentonite-water based drilling fluids (BT-WDFs) and describes how its particle size and concentration influence on the filtration property of SPI/BT-WDFs. It was found that high pressure homogenization (HPH)-treated SPI had superior filtration property over that of native SPI due to the improved ability for the plugging pore throat. HPH treatment also caused a significant change in the surface characteristic of SPI, leading to a considerable surface interaction with BT in aqueous solution. The concentration of SPI had a significant impact on the dispersion state of SPI/BT mixtures in aquesous solution. At low SPI concentrations, strong aggregations were created, resulting in the formation of thick, loose, high-porosity and high-permeability filter cakes and high fluid loss. At high SPI concentrations, intercatlated/exfoliated structures were generated, resulting in the formation of thin, compact, low-porosity and low-permeability filter cakes and low fluid loss. The SPI/BT-WDFs exhibited superior filtration property than pure BT-WDFs at the same solid concentraion, demonstrating the potential utilization of SPI as an effective, renewable, and biodegradable fluid loss reducer in well excavation applications.
Induced Cell Clustering Enhances Islet <i>β</i> Cell Formation from Human Cultures Enriched for Pancreatic Ductal Epithelial Cells (2006)

A better understanding of the culture conditions that stimulate in vitro beta-cell differentiation from islet precursors would be useful for optimizing the production of tissue-engineered islets. In this study, high- and low-adherent substrates and high- and low-serum media were used to control the clustering of human pancreatic ductal epithelial cells and to determine its effect on their transdifferentiation to beta cells. While the initial epithelial cell cultures were devoid of any beta cells as assessed by dithizone staining, dithizone+ cells were generated during the next 3 weeks under all culture conditions. Although the rate of transdifferentiation was low, a approximately 4-fold greater number and percentage of dithizone+ cells were generated following 23-24 days of culture in the least adherent conditions (low-serum medium, low-adherent substrate), which stimulated cell clustering to the highest degree. Insulin immunohistochemistry data correlated well with the dithizone data (r(2) = 0.99), evidence that dithizone is a reliable measure of insulin+ cells. The preferential distribution of the dithizone+ cells to regions of cell aggregation and the increased efficiency of transdifferentiation in conditions that promote cell clustering suggest that cell-cell interactions and/or cell shape changes are important to the transdifferentiation of adult pancreatic ductal epithelial cells to beta cells in vitro.
Cryptochrome as a Sensor of the Blue/Green Ratio of Natural Radiation in Arabidopsis (2010)

Green light added to blue light has been proposed to shift cryptochromes from their semireduced active form to the reduced, inactive state. Whether the increased proportion of green light observed under leaf canopies compared to open places reduces cryptochrome-mediated effects remained to be elucidated. Here we report that the length of the hypocotyl of Arabidopsis (Arabidopsis thaliana) seedlings grown under controlled conditions decreased linearly with increasing blue/green ratios of the light within the range of ratios found in natural environments. This effect was stronger under higher irradiances. We developed a model, parameterized on the basis of field experiments including photoreceptor mutants, where hypocotyl growth of seedlings exposed to different natural radiation environments was related to the action and interaction of phytochromes and cryptochromes. Adding the blue/green ratio of the light in the term involving cryptochrome activity improved the goodness of fit of the model, thus supporting a role of the blue/green ratio under natural radiation. The blue/green ratio decreased sharply with increasing shade by green grass leaves to one-half of the values observed in open places. The impact of blue/green ratio on cryptochrome-mediated inhibition of hypocotyl growth was at least as large as that of irradiance. We conclude that cryptochrome is a sensor of blue irradiance and blue/green ratio.
Automated prediction of adverse post-surgical outcomes (2014)

Patients undergoing surgery can experience a range of adverse events, such as renal and cardiac injury, respiratory failure, and death. This study focuses on discovering relationships between perioperative physiological data and adverse post-surgical outcomes, with the goal of developing strategies to reduce the severity and frequency of these conditions. Analyzing the patient's preoperative demographic data, such as age and race, and perioperative physiologic data, such as blood pressure and anesthesia dosage, we use statistical models to predict whether a patient under anesthesia will develop renal or cardiac injury, respiratory failure, or death. Specifically, we compare generalized linear models, random forest models, and L <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> regularized logistic regression models in predicting these adverse events. For each event, the random forest model generally outperformed its competitors, as shown in receiver operating characteristic (ROC) curves and evidenced by the higher area under the curve (AUC) values of 0.85, 0.86, 0.85, and 0.82 for death, renal injury, respiratory failure, and cardiac injury, respectively. However, score tables indicate that at certain thresholds, the L <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> regularized logistic regression predicts fewer false negatives than the random forest models. In general, our findings show the existence of a relationship between perioperative predictors and post-surgical complications. This relationship could provide the foundation for a surveillance and alert system.
Predicting popularity dynamics of online contents using data filtering methods (2016)

This paper proposes a new prediction process to explain and predicts popularity evolution of YouTube videos. We exploit prior study on the classification of YouTube videos in order to predict the evolution of videos' view-count. This classification allows to identify important factors of the observed popularity dynamics. In particular, we use this classification as filtering method allowing to identify the factors responsible for this popularity evolution. Results given by extensive experiments show that the proposed prediction process is able to reduce the average prediction errors compared to a state-of-the-art baseline model. We also evaluate the impact of adding popularity criteria in the classification.
Novel collector design for high-speed SiGe:C HBTs (2003)

We describe a novel collector design for high-frequency SiGe:C HBTs without deep trenches and with low-resistance collectors formed by high-dose ion implantation after shallow trench formation. f/sub T/ values of 200 GHz at BV/sub CEO/=2.0 V and ring oscillator delays of 4.3 ps are obtained. Excellent static characteristics and high yield were achieved for the HBT module integrated in a 0.25 /spl mu/m CMOS platform.
Pharmacodynamics, pharmacokinetics and safety of multiple ascending doses of the novel dual glucose‐dependent insulinotropic polypeptide/glucagon‐like peptide‐1 agonist <scp>RG</scp> 7697 in people with type 2 diabetes mellitus (2017)

Daily doses of RG7697 for 2 weeks were well tolerated by the majority of patients with T2D. Pharmacokinetic data supported once-daily dosing and pharmacodynamic effect displayed dose-dependent reductions in fasting and postprandial plasma glucose, without increasing the risk of hypoglycaemia.
The effect of personal and professional cultural values towards the marketing ethics of academicians (2011)

This study assesses the personal cultural values and professional values of academicians in regards to marketing ethics. This research uses Singhapakdi and Vitell’s (1993) marketing norms scale and professional value scale together with Yoo and Donthu’s (2002) three dimensional measures of culture operation alised at the individual level. The findings showed that Uncertainty Avoidance and Professional Values influenced academicians’ marketing ethics. It is therefore suggested that managers should look into methods and ways of cultivating professionalism among academicians in order for them to possess good marketing ethics. The findings also showed that demographic factors such as age, gender, years of working experience, academic qualification do not have any influence on academicians’ marketing ethics. Other implications of the study were also discussed.
Synthesis and Anion‐Binding Properties of Novel Redox‐Active Calixarene Receptors (2008)

Abstract A novel synthetic approach towards redox‐active calixarene‐based receptors is described in which ferrocene fragments were introduced at the lower rim through anion‐binding urea or amide connections. These derivatives were prepared in one pot by treating an amine‐containing calixarene with ferrocenecarboxylic acid in the presence of diphenylphosphoryl azide and diisopropylethylamine. This method allows a convergent approach to these receptors and is readily adaptable to the introduction of other urea substituents. The anion‐binding properties of these artificial receptors have been revealed by NMR spectroscopy and thoroughly investigated by electrochemical methods. We have assessed the importance of the urea–phosphate bonds in the observed electrochemical response by studying receptors in which the ferrocene reporters and binding fragments are closely associated or fully disconnected through a long alkyl chain. The experimental results clearly show the utmost importance of ion‐pairing effects in the electrochemical recognition process, which account for most of the transduction signal in organic apolar media. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)