gebhart/patrepeval huggingface dataset:
Predictive Model-Based Thermal Management for Network Applications (2011)

As processor power density has increased at an alarming rate, chip/core temperature control becomes critical in satisfying given thermal constraint and avoiding hotspots. Unlike "run-to-finish" applications whose temperature will simply rise to saturation point and then stabilize, network applications do periodic packet processing, which causes temperature to rise and fall over time. However, no existing studies have focused on characterizing the temperature variation for periodic tasks. We envision that volatile thermal behavior has to be well understood in order to optimize thermal management. In this paper, we first build a novel predictive thermal model for generic periodic tasks running on a single core. This model can dynamically derive the core temperature at any time quickly and accurately. To verify the model, we use both Hot Spot simulator and a real Linux machine to run six network applications chosen from Net Bench. Then, we propose an online model update strategy using on-chip thermal sensors, which can effectively correct incidental errors by adjusting model parameters "on-the-fly". Finally, by combining the thermal model and the online update, we design, implement and evaluate a predictive model-based thermal management scheme on an Intel Xeon E5335 core for network applications based on the Stop & Go technique. Compared with two other alternatives, our scheme achieves lower temperature, higher throughput, no thermal constraint violation, and negligible overhead cost.
Practical information-flow aware middleware for in-car communication (2013)

Today's vehicles are increasingly connected to Internet, devices and integrate more and more electronic components. More than just ensuring their passengers' safety, which remains nevertheless one of their main objectives, cars have to deal with private information and encounters the same security issues as traditional computers. Until recently, automotive technologies allowed very little space for security, but the transition towards full Ethernet-based on-board network will change this situation. In this paper, we present solutions for decentralized information flow control in order to enhance the security and privacy level of the car data management. We describe the implementation of these mechanisms in an automotive middleware and propose its evaluation.
Fast HEVC intra-prediction mode decision based on conditional selection with hybrid cost ranking (2015)

To improve rate-distortion (R-D) performance, high efficiency video coding (HEVC) increases the intra-prediction modes with heavy computational load, and thus the intra coding optimization is highly demanded for real-time applications. According to the conditional probability of most probable mode and the correlation of potential candidate subsets, this paper proposes a fast HEVC intra-prediction mode decision scheme based on conditional selection with hybrid cost ranking. The proposed scheme utilizes the coding results of both rough mode decision and neighboring prediction units to obtain a potential candidate subset, and then conditionally selects the optimal mode through early likelihood decision and hybrid cost ranking. The experimental results demonstrate that the proposed scheme averagely provides about 22.1% encoding speedup with just 0.86% BD-rate loss in comparison with default fast intra prediction in HM16.0. Compared to other fast intra-prediction mode decision schemes, the proposed scheme also significantly reduces intra-coding time while maintaining similar R-D performance in all-intra main profile.
MODIFIED HEMOGLOBIN REDUCES CATECHOLAMINE REQUIREMENTS IN AN OVINE MODEL OF SEPTIC SHOCK. (1996)

Bone, H.; Schenarts, P.; Fischer, S.; Booke, M.; Traber, L,; Traber, D, Author Information
An approach to a non-contact vital sign monitoring using dual-frequency microwave radars for elderly care (2013)

This study aimed to produce a prototype system for non-contact vital sign monitoring of the elderly using microwave radar with the intention of reducing the burdens on monitored individuals and nursing caregivers. In addition, we tested the ability of the proposed prototype system to measure the respiratory and heart rates of the elderly in a nursing home and discussed the systems effectiveness and problems by examining results of real-time monitoring. The prototype system consisted of two 24-GHz microwave radar antennas and an analysis system. The antennas were positioned below a mattress to monitor motion on the body surface for measuring cardiac and respiratory rates from the dorsal side of the subjects (23.3 ± 1.2 years) who would be lying on the mattress. The heart rates determined by the prototype system correlated significantly with those measured by electrocardiography (r = 0.92). Similarly, the respiratory rates determined by the prototype correlated with those obtained from respiration curves (r = 0.94). Next, we investigated the effectiveness of the prototype system with 7 elderly patients (93.3 ± 10.56 years) at a nursing home. The proposed system appears to be a promising tool for monitoring the vital signs of the elderly in a way that alleviates the need to attach electrodes overnight to confirm patient safety.
Recombinant guinea pig and human RANTES activate macrophages but not eosinophils in the guinea pig (1997)

To characterize the biologic activities of potential mediators of allergic inflammation, we have cloned, expressed, and purified guinea pig RANTES (gpRANTES). cDNA for gpRANTES was cloned from Con A-stimulated guinea pig spleen cells. A high level of gpRANTES expression in Escherichia coli was achieved by mutation of a human RANTES (hRANTES) expression construct to obtain a 68-amino acid protein identical with the predicted guinea pig amino acid sequence, assuming an equivalent amino terminus as the human protein. Purified gpRANTES was an effective stimulus of human eosinophils as assessed by increases in intracellular free calcium in fura-2-loaded cells and chemotactic responses in vitro. gpRANTES exhibits similar potency and efficacy to hRANTES. In marked contrast, neither gpRANTES nor hRANTES was able to activate guinea pig peritoneal eosinophils in these assays, even in the presence of IL-5. However, gpRANTES was found to be a potent stimulator of guinea pig peritoneal macrophages. Following tracheal instillation of gpRANTES, a dose-dependent increase in macrophages, but not eosinophils, was observed in gpBAL. Macrophage accumulation was detectable by 6 h and sustained for at least 48 h. These results indicate that RANTES in the guinea pig may have a different cellular selectivity than that described in the human, which may be important in the use of animal models in the analysis of allergic disorders. These selectivities do not appear to be accounted for by differences in guinea pig and human RANTES sequences.
Experimental Studies On Porous Wick Flat Plate Heat Pipe (2010)

In recent years, the use of heat pipe for electronic equipments thermal management has been growing faster to meet the future requirements.The flat plate heat pipes (FPHP) are promising heat transporting devices capable of transmitting high heat fluxes rejected by modern electronic equipments.In the present study, the experimental analysis of the thermal performance of flat plate heat pipe is carried out for various heat input rates with different working fluids.Quantity of working fluid charged into the heat pipe is varied and its influence on performance is obtained.Different working fluids have been tested with heat pipe and their performance has been compared.At lower heat flux the fluids such as acetone, ethanol, and methanol are better than water, whereas at higher heat flux water is best candidature among these fluids considered.
Photoelectrochemical Properties of Iron-Oxide Films and the Coating Effects onto n-Si as an Efficient Photoanode (1982)

The photoelectrochemical properties of iron-oxide thin films prepared by various techniques have been investigated extensively, and it was found that the quantum efficiency of the photoresponse is low for visible light. Iron-oxide films have been used in fabricating heterostructure electrodes composed of Si coated with iron-oxide. This iron-oxide/Si heterostructure has been characterized by X-ray diffraction, Auger electron spectroscopy and capacitance measurements, and Auger analysis has shown that the substances of the heterostructure interdiffuse deep across the interface. Some possible energy diagrams for the heterostructure are proposed.
Inhibition of Cyclin D1 Kinase Activity Is Associated with E2F-Mediated Inhibition of Cyclin D1 Promoter Activity through E2F and Sp1 (1998)

Coordinated interactions between cyclin-dependent kinases (Cdks), their target "pocket proteins" (the retinoblastoma protein [pRB], p107, and p130), the pocket protein binding E2F-DP complexes, and the Cdk inhibitors regulate orderly cell cycle progression. The cyclin D1 gene encodes a regulatory subunit of the Cdk holoenzymes, which phosphorylate the tumor suppressor pRB, leading to the release of free E2F-1. Overexpression of E2F-1 can induce apoptosis and may either promote or inhibit cellular proliferation, depending upon the cell type. In these studies overexpression of E2F-1 inhibited cyclin D1-dependent kinase activity, cyclin D1 protein levels, and promoter activity. The DNA binding domain, the pRB pocket binding region, and the amino-terminal Sp1 binding domain of E2F-1 were required for full repression of cyclin D1. Overexpression of pRB activated the cyclin D1 promoter, and a dominant interfering pRB mutant was defective in cyclin D1 promoter activation. Two regions of the cyclin D1 promoter were required for full E2F-1-dependent repression. The region proximal to the transcription initiation site at -127 bound Sp1, Sp3, and Sp4, and the distal region at -143 bound E2F-4-DP-1-p107. In contrast with E2F-1, E2F-4 induced cyclin D1 promoter activity. Differential regulation of the cyclin D1 promoter by E2F-1 and E2F-4 suggests that E2Fs may serve distinguishable functions during cell cycle progression. Inhibition of cyclin D1 abundance by E2F-1 may contribute to an autoregulatory feedback loop to reduce pRB phosphorylation and E2F-1 levels in the cell.
Solid Freeform Fabrication An Advanced Manufacturing Approach (2018)

Solid freeform fabrication (SFF) is the production of freeform solid objects directly from a\ncomputer model without part-specific tooling or human intervention. SFF has been realized in the\nlast ten years through the merging of several previously distinct technologies: computer science,\nmechanical design, controls, high-energy beam technology and materials science and engineering.\nTheir combination has produced over a relatively short time..frame numerous SFF methods. The\nvalue of SFF to the commercial sector is usually articulated in terms of reduced time to market\n(prototyping), low production "one-of-a-kind" parts and patterns for casting. The purpose of this\nintroductory paper is to describe briefly some of the approaches to SFF as a background for the\narticles included in this proceedings.
A Study on the Effect of Air Pollutants in Daegu Area by Biological Indicator of Roadside (1988)

This study was performed to investigate the air pollution levels in Daegu area titrough measuring of contents of water, chlorophyll, water soluble sulfur and lead metal in the leaves of roadside trees and chemical properties of soil under the urban trees. The results can be summarized as follows 1. The range of water content was from 60.4% to 74.6%. The comparisons of chlorophyll, water soluble sulfur and water content were regression equation, chlorophyll=0.1981+ 0.0040 water content (July), water soluble sulfur=3,139-0.0416 water content (July). and correlation coefficient, r=0.561 and r=0.549 respectively 2. Average contents of chlorophyll, water soluble sulfur and lead metal in the leaves of roadside tree at sampling sites were chlorophyll 0.050, 0.072mg/cm$^2$, water soluble sulfur 0.244, 0.333%, and lead metal 12.25, 12.68ppm in Oct. and Jul. respectively. 3. Correlation between chlorophyll and contents of water soluble sulfur and lead metal in the leaves of roadside tree at sampling sites were water soluble sulfur r=-0.564, -0.613 and lead metal r=-0.693, -0.699 in October and July, respectively. 4. Correlation between chlorophyll and water content, water soluble sulfur and lead metal in the leaves of tree showed positive significance.
Detection and Identification of Transcription Factors as Interaction Partners of Alien in vivo (2007)

Interacting proteins are often involved in the same cellular processes, and thus the identification of interacting partners of a given protein with unknown function may give insight into the physiological role of this protein. For the detection of protein-protein interactions of the corepressor Alien we used a proteomic approach comprising mass spectrometry and immunological techniques. We assessed solely endogenously expressed proteins. In this study we present for the first time that Alien is interacting within a network of proteins involved in transcriptional regulation, DNA repair, and cell cycle in vivo. In this way we detected protein interactions of Alien involving nucleophosmin, ERCC3, TRIP11, as well as CRSP3.
Address mapping and the control of access in an interactive computer (1967)

Computer system designs have attempted to maximize machine utilization (sometimes called efficiency) without regard to other important factors including the human effort and elapsed time required to solve problems. In recent years some computing systems have been developed which provide communication and control means by which users can interact with their own computing processes and with each other. Initial use of these systems has demonstrated their superiority in computer-aided problem solving applications. These interactive computing systems are mainly adaptations of conventional computing systems and are far from ideal in many respects. This paper describes a much improved mechanism for protection, address mapping, and subroutine linkage for an interactive computing system.
Optimization of Meropenem Minimum Concentration/MIC Ratio To Suppress In Vitro Resistance of <i>Pseudomonas aeruginosa</i> (2005)

Suppression of resistance in a dense Pseudomonas aeruginosa population has previously been shown with optimized quinolone exposures. However, the relevance to beta-lactams is unknown. We investigated the bactericidal activity of meropenem and its propensity to suppress P. aeruginosa resistance in an in vitro hollow-fiber infection model (HFIM). Two isogenic strains of P. aeruginosa (wild type and an AmpC stably derepressed mutant [MIC = 1 mg/liter]) were used. An HFIM inoculated with approximately 1 x 10(8) CFU/ml of bacteria was subjected to various meropenem exposures. Maintenance doses were given every 8 h to simulate the maximum concentration achieved after a 1-g dose in all regimens, but escalating unbound minimum concentrations (C(min)s) were simulated with different clearances. Serial samples were obtained over 5 days to quantify the meropenem concentrations, the total bacterial population, and subpopulations with reduced susceptibilities to meropenem (>3x the MIC). For both strains, a significant bacterial burden reduction was seen with all regimens at 24 h. Regrowth was apparent after 3 days, with the C(min)/MIC ratio being < or = 1.7 (time above the MIC, 100%). Selective amplification of subpopulations with reduced susceptibilities to meropenem was suppressed with a C(min)/MIC of > or = 6.2 or by adding tobramycin to meropenem (C(min)/MIC = 1.7). Investigations that were longer than 24 h and that used high inocula may be necessary to fully evaluate the relationship between drug exposures and the likelihood of resistance suppression. These results suggest that the C(min)/MIC of meropenem can be optimized to suppress the emergence of non-plasmid-mediated P. aeruginosa resistance. Our in vitro data support the use of an extended duration of meropenem infusion for the treatment of severe nosocomial infections in combination with an aminoglycoside.
High average power first-order distributed feedback quantum cascade lasers (2000)

We present distributed feedback quantum cascade lasers at 965 cm/sup -1/ with a high average optical output power at temperatures of up to 60/spl deg/C. At a duty cycle of 3%, the averaged maximal output power of a 55-μm wide and 1.5-mm-long device at -30/spl deg/C was 13.6 mW; at 60/spl deg/C, the device emitted 2 mkV. Corresponding peak optical powers of 450 mW at -30/spl deg/C and of 70 mW at 60/spl deg/C have been observed. Due to the lateral current injection, we achieved single-mode behavior in a slightly distorted zero-order lateral mode across the whole range of investigated temperatures and output powers. At room temperature, the threshold current density was on the order of 6.7 kA/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> ; the characteristic temperature T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> was, due to tuning of the Bragg resonance into the gain curve, rather high, namely 310 K.
Part II: Targeted Particles for Imaging of Anticancer Immune Responses (2011)

The interaction of dendritic cells (DCs) and T cells has been the cornerstone of approaches to cancer immunotherapy. Antitumoral immune responses can be elicited by delivering cancer antigens to DCs. As antigen presenting cells, these DCs activate cancer antigen specific T cells. Whereas the first part of the review discusses methods for delivery of cancer vaccines to DCs, in this part the focus is on the potential role of nanoscopic devices for molecular imaging of these immune responses. Nanoscopic devices could potentially deliver tracking molecules to DCs, enabling monitoring of DCs and/or T cell activation and tumoricidal activity during immunotherapy, using non-invasive imaging modalities such as nuclear imaging (single photon emission computed tomography (SPECT), positron emission tomography (PET)), magnetic resonance imaging (MRI) and optical imaging.
The Nucleotide Specificity and Feedback Control of Thymidine Diphosphate d-Glucose Pyrophosphorylase (1965)

A large number of nucleotide diphosphate sugar pyrophosphorylases have been described (for review see References 1 and 2), but only a few of these have been purified to any significant extent. In this paper we report the further purification of deoxythymidine diphosphate n-glucose pyrophosphorylase from Pseudomonas ueruginosa (3). With this partially purified enzyme, it is possible to show that this enzyme will utilize not only thymidine nucleotides as substrates but also uridine nucleotides and deoxyuridine nucleotides. The control of the enzymatic reactions involved in the biosynthesis of structural polysaccharides has only recently become a subject of investigation. In particular, Kornfeld et al. (4) have shown that UDP-GlcNAc is a feedback inhibitor of the n-fructose 6-phosphate-L-glutamine amidotransferase, and also that CMPN-acetylneuraminic acid is an inhibitor of the enzyme that cleaves UDP-GlcNAc to N-acetyl-n-mannosamine. In each case the end product inhibits the first enzyme that is unique to its biosynthetic pathway. It is shown in this paper that the dTDP-n-glucose pyrophosphorylase is subject to feedback inhibition by dTDP-Lrhamnose. In an accompanying paper, Bernstein and Robbins (5) describe related observations obtained independently on the dTDP-nglucose pyrophosphorylase and the UDP-n-glucose pyrophosphorylase from Salmonella.
Cross-Correlation and Sine-Fitting Techniques for High Resolution Ultrasonic Ranging (2006)

This paper presents a combination of two techniques for high resolution ultrasonic distance measurements in air. The first is the cross-correlation between transmitted and received signals to determine the time-of-flight (TOF), and the second is the sine-fitting to determine the phase-shift between these signals. Sine-fitting can estimate the phase-shift with very high accuracies. The result of this synergy is very accurate distance measurements
Cloning and nucleotide sequence of the gene encoding yeast ribosomal protein YS25 (1988)

Clones encoding ribosomal protein YS25⋆ (1,2) were isolated from a genomic DNA library of Saccharomyces cerevisiae using synthetic oligonucleotides corresponding to the partial amino acid sequences of the protein. These sequence analyses suggest that the YS25 gene has an intron containing some features (underlined) in common with the other yeast ribosomal protein genes already determined, the ‘TACTAAC box’ of which is not strictly conserved. In complete agreement with the primary structure of protein YS25 previously reported (1), the amino acid sequence, deduced from the largest open reading frame, resulted in being split by the putative intron.
Über Pterinchemie. 50. Mitteilung [1]. <sup>13</sup>C‐NMR.‐Spektren von 7,8‐Dihydro‐ und 5,6,7,8‐Tetrahydrofolsäure (1974)

Es wird eine verbesserte, leichte und mit guter Ausbeute verlaufende Herstellungsmethode für reine Tetrahydrofolsäure beschrieben. Die 13 C‐NMR.‐Spektren von Dihydro‐ und Tetrahydrofolsäure werden diskutiert.
COMPARISON BETWEEN TWO GENERIC 3D BUILDING RECONSTRUCTION APPROACHES – POINT CLOUD BASED VS. IMAGE PROCESSING BASED (2016)

Abstract. This paper compares two generic approaches for the reconstruction of buildings. Synthesized and real oblique and vertical aerial imagery is transformed on the one hand into a dense photogrammetric 3D point cloud and on the other hand into photogrammetric 2.5D surface models depicting a scene from different cardinal directions. One approach evaluates the 3D point cloud statistically in order to extract the hull of structures, while the other approach makes use of salient line segments in 2.5D surface models, so that the hull of 3D structures can be recovered. With orders of magnitudes more analyzed 3D points, the point cloud based approach is an order of magnitude more accurate for the synthetic dataset compared to the lower dimensioned, but therefor orders of magnitude faster, image processing based approach. For real world data the difference in accuracy between both approaches is not significant anymore. In both cases the reconstructed polyhedra supply information about their inherent semantic and can be used for subsequent and more differentiated semantic annotations through exploitation of texture information.