gebhart/patrepeval huggingface dataset:
New Left and Old Far Right: Tolerating the Intolerable (2009)

This chapter criticises what passes for contemporary Left-wing radicalism. My main concern is as follows. While it is obvious that a radical, psychopathic movement of the far Right is sweeping the world, it is far from obvious that Left-minded and liberal-minded people are prepared to oppose it. A characteristic of the Left, I would argue a defining characteristic, is that Left-wingers excuse, turn their eyes from, or on occasion, openly support movements which are against everything they profess to believe in. Before going on to briefly explore why this situation has come about, I’ll give you a few examples to illustrate my point.
Damage in laser materials : (1971)

Approximately 50 attendees at the symposium heard 17 papers on topics relating to laser-induced damage in glass, crystalline materials, nonlinear optical materials, thin film dielectric coatings, and mirrors. Particular attention was given to the processes of plasma formation at dielectric surfaces, and to the role played by self-focusing in bulk damage in solids. The principal conclusions arrived at the Symposium, the content of each of the papers, and recommendations for future investigations are summarized below.
Fitness of Anopheline Mosquitoes Expressing Transgenes That Inhibit Plasmodium Development (2004)

One potential strategy for the control of malaria and other vector-borne diseases is the introduction into wild vector populations of genetic constructs that reduce vectorial capacity. An important caveat of this approach is that the genetic construct should have minimal fitness cost to the transformed vector. Previously, we produced transgenic Anopheles stephensi expressing either of two effector genes, a tetramer of the SM1 dodecapeptide or the phospholipase A2 gene (PLA2) from honeybee venom. Mosquitoes carrying either of these transgenes were impaired for Plasmodium berghei transmission. We have investigated the role of two effector genes for malaria parasite blockage in terms of the fitness imposed to the mosquito vector that expresses either molecule. By measuring mosquito survival, fecundity, fertility, and by running population cage experiments, we found that mosquitoes transformed with the SM1 construct showed no significant reduction in these fitness parameters relative to nontransgenic controls. The PLA2 transgenics, however, had reduced fitness that seemed to be independent of the insertion site of the transgene. We conclude that the fitness load imposed by refractory gene(s)-expressing mosquitoes depends on the effect of the transgenic protein produced in that mosquito. These results have important implications for implementation of malaria control via genetic modification of mosquitoes.
Oracle Database 10g: A Beginner's Guide (2004)

Get a Solid Foundation in Oracle Database Technology

Master Oracle Database 11g fundamentals quickly and easily. Using self-paced tutorials, this book covers core database essentials, the role of the administrator, high availability, and large database features. Oracle Database 11g: A Beginner's Guide walks you, step by step, through database setup, administration, programming, backup, and recovery. In-depth introductions to SQL and PL/SQL are included. Designed for easy learning, this exclusive Oracle Press guide offers: 

Core Concepts--Oracle Database 11g topics presented in logically organized chapters 
Critical Skills--Lists of specific skills covered in each chapter 
Projects--Practical exercises that show how to apply the critical skills learned in each chapter 
Progress Checks--Quick self-assessment sections to check your progress 
Notes--Extra information related to the topic being covered
Mastery Checks--Chapter-ending quizzes to test your knowledge 


Table of contents
Acknowledgments
Introduction
Chapter 1. Database Fundamentals
Chapter 2. Installing Oracle
Chapter 3. Connecting to Oracle
Chapter 4. SQL: Structured Query Language
Chapter 5. PL/SQL
Chapter 6. The Database Administrator
Chapter 7. Backup & Recovery
Chapter 8. High Availability: RAC, ASM, and Data Guard
Chapter 9. Large Database Features
Appendix A: Mastery Check Answers
Index
Animal models in the drug discovery pipeline for Alzheimer's disease (2011)

With increasing feasibility of predicting conversion of mild cognitive impairment to dementia based on biomarker profiling, the urgent need for efficacious disease-modifying compounds has become even more critical. Despite intensive research, underlying pathophysiological mechanisms remain insufficiently documented for purposeful target discovery. Translational research based on valid animal models may aid in alleviating some of the unmet needs in the current Alzheimer's disease pharmaceutical market, which includes disease-modification, increased efficacy and safety, reduction of the number of treatment unresponsive patients and patient compliance. The development and phenotyping of animal models is indeed essential in Alzheimer's disease-related research as valid models enable the appraisal of early pathological processes - which are often not accessible in patients, and subsequent target discovery and evaluation. This review paper summarizes and critically evaluates currently available animal models, and discusses their value to the Alzheimer drug discovery pipeline. Models dealt with include spontaneous models in various species, including senescence-accelerated mice, chemical and lesion-induced rodent models, and genetically modified models developed in Drosophila melanogaster, Caenorhabditis elegans, Danio rerio and rodents. Although highly valid animal models exist, none of the currently available models recapitulates all aspects of human Alzheimer's disease, and one should always be aware of the potential dangers of uncritical extrapolating from model organisms to a human condition that takes decades to develop and mainly involves higher cognitive functions.
Naphthalenone and Phthalide Metabolites from <i>Lachnum papyraceum</i> (1997)

A new naphthalenone derivative (2a) and a phthalide (6a), as well as a methyl ester (6b), were isolated from submerged cultures of Lachnum papyraceum, together with known naphthalenone, phthalide, and chromanol derivatives. The structures of the new compounds, of which 2a possesses weak antimicrobial and phytotoxic activities and weak cytotoxicity, were determined by spectroscopic methods.
Genetic Characterization of the<i>Klebsiella pneumoniae waa</i>Gene Cluster, Involved in Core Lipopolysaccharide Biosynthesis (2001)

A recombinant cosmid containing genes involved in Klebsiella pneumoniae C3 core lipopolysaccharide biosynthesis was identified by its ability to confer bacteriocin 28b resistance to Escherichia coli K-12. The recombinant cosmid contains 12 genes, the whole waa gene cluster, flanked by kbl and coaD genes, as was found in E. coli K-12. PCR amplification analysis showed that this cluster is conserved in representative K. pneumoniae strains. Partial nucleotide sequence determination showed that the same genes and gene order are found in K. pneumoniae subsp. ozaenae, for which the core chemical structure is known. Complementation analysis of known waa mutants from E. coli K-12 and/or Salmonella enterica led to the identification of genes involved in biosynthesis of the inner core backbone that are shared by these three members of the Enterobacteriaceae. K. pneumoniae orf10 mutants showed a two-log-fold reduction in a mice virulence assay and a strong decrease in capsule amount. Analysis of a constructed K. pneumoniae waaE deletion mutant suggests that the WaaE protein is involved in the transfer of the branch beta-D-Glc to the O-4 position of L-glycero-D-manno-heptose I, a feature shared by K. pneumoniae, Proteus mirabilis, and Yersinia enterocolitica.
Dancing Across the Pond: Telematic Pedagogy and Performance (2013)

ABSTRACT This article focuses on the telematic dance performance work Woven Space Across the Pond (2009) created by Pauline Brooks and Luke Kahlich, with Nathaniel “Beau” Hancock. It involved students from the dance departments of two universities, one in the United States and one in the United Kingdom. It was performed synchronously so that audiences shared time, but not space. Dancers created a new performance environment where they became one company united through the virtual “shared space” of the cone-of-capture. Contextualization will be made of the larger, four-year-long international collaborative research endeavor to explore choreographic Internet pedagogy through project-based research over the Internet. Analysis and evaluation will be made of the strategies employed to engage dance students and audiences in new areas of performance, as well the performers' responses to the devising, rehearsing, and performance process and of the audience's response to the work, the performers, and the viewing experience.
Measurement of reflection high-energy electron diffraction oscillations during molecular-beam epitaxial growth of GaAs on a rotating substrate (1992)

A technique has been developed for the measurement and analysis of reflection high-energy electron diffraction (RHEED) oscillations occurring during molecular-beam epitaxy on a rotating substrate. Previously, it has been necessary to stop substrate rotation in order to perform RHEED oscillation analysis. This limitation has been overcome by combining a computerized video tracking system with a previously reported technique for frequency-domain analysis.
Design Methodology Based on the Inversion Coefficient and its Application to Inductorless LNA Implementations (2019)

The Internet of Things (IoT) entails new challenges for the development of wireless transceivers. Radio-frequency building blocks require complex design flows in order to address very different sets of specifications. This paper presents a three-step design methodology dedicated to the synthesis of RF building blocks. Based on the inversion coefficient, the proposed design methodology allows the optimization of the circuit performance for any CMOS process and any application. It is illustrated through the implementation of inductorless low-noise amplifiers (LNA) in three different CMOS nodes: 28-nm fully-depleted silicon-on-insulator (FDSOI), and 65 and 130-nm Bulk. These LNAs are dedicated to two cases of IoT applications: multi-standard and ultra low power. The proposed circuits achieve the state-of-the-art performance for all nodes and applications. Furthermore, the methodology enables an insightful comparison of the capabilities of the different CMOS nodes in terms of power consumption, noise, and bandwidth.
Ferroelectricity in Si‐Doped HfO<sub>2</sub> Revealed: A Binary Lead‐Free Ferroelectric (2014)

Static domain structures and polarization dynamics of silicon doped HfO2 are explored. The evolution of ferroelectricity as a function of Si-doping level driving the transition from paraelectricity via ferroelectricity to antiferroelectricity is investigated. Ferroelectric and antiferroelectric properties can be observed locally on the pristine, poled and electroded surfaces, providing conclusive evidence to intrinsic ferroic behavior.
Comparison of time-resolved autofluorescence in the eye-ground of healthy subjects and patients suffering from age-related macular degeneration (2005)

Age-related macular degeneration (AMD) is the most frequent cause for blindness for person older than 65 years in western countries. Besides the subjective pain, it is also an economic problem in the ageing population. As the pathomechanism is unknown, no curative treatment is possible. International research for discovering of early age-related alterations at the fundus is directed on in vivo measurements of autofluorescence. One way is the measurement of fluorescence spectra. Unfortunately, any selective excitation of fluorophores is excluded by the absorption edge of the ocular media at 400 nm. Furthermore, the shape of fluorescence spectra is influenced by the spectral absorption of layers in front of the emitting fluorophore. Weakly emitting fluorophores are covered by intensive emitting substances. The most serious limitation in fluorescence measurements of the living human fundus is the maximal permissible exposure. For that reason, fluorescence spectra of the fundus can not be detected with a high spatial resolution. The detection of dynamic fluorescence provides substance-specific lifetimes Ti, amplitudes A<sub>i</sub>, and information about the relative contribution Q<sub>i</sub> of components in fluorescence images. As these parameters are calculated for each image point, diagrams of T<sub>i</sub> vs. T<sub>j</sub>, A<sub>i</sub> vs. A<sub>j</sub>, and Q<sub>i</sub> vs. Q<sub>j</sub> can be drawn, in which specific clusters appear for healthy subjects or AMD - patients. The projection of lifetime - clusters onto corresponding axis represents histogram of the considered lifetime. The slope in the correlation between Ai and Aj can also be used as a discriminating mark. Considering image lines as intersection through characteristic anatomical structures (optic disc, macula) profiles of T<sub>i</sub>, A<sub>i</sub>, or Q<sub>i</sub> show changes of these parameters (e.g. depigmentation) as function of location, which might be specific for AMD.
Characterization of a Human Monoclonal Antibody against Shiga Toxin 2 Expressed in Chinese Hamster Ovary Cells (2005)

Shiga toxin-producing Escherichia coli infections can often lead to the development of hemolytic-uremic syndrome (HUS) in a small percentage of infected humans. Patients with HUS receive only supportive treatment as the benefit of antibiotic therapy remains uncertain. We have previously reported the generation and preclinical evaluation of neutralizing human monoclonal antibodies (HuMAbs) against the Shiga toxins (Stx). In this paper, we describe the expression in Chinese hamster ovary (CHO) cells of 5C12 HuMAb, which is directed against the A subunit of Stx2. The cDNAs of the light and heavy chain immunoglobulin (Ig) variable regions of 5C12 HuMAb were isolated and cloned into an expression vector containing human IgG1 constant regions. The vector was transfected into CHO cells, and transfectants secreting Stx2-specific antibody were screened by an Stx2-specific enzyme-linked immunosorbent assay. The CHO-produced recombinant 5C12 (r5C12) showed similar specificity and binding affinity to Stx2 as the parent hybridoma-produced 5C12. More significantly, the r5C12 displayed the same neutralizing activity as the parent 5C12 in vitro and in vivo. In the mouse toxicity model, both antibodies significantly and equally prolonged survival at a dose of 0.312 microg/mouse. The data showed that since r5C12, produced in CHO cells, was equally effective as the parent 5C12, it is our choice candidate as a potential prophylactic or therapeutic agent against hemolytic-uremic syndrome.
Prospects for x-ray fabrication of Si IC devices (1975)

In this paper we report on low-x-ray-attenuation Si vacuum windows for use with Al K x-ray sources and the fabrication of 5.5-cm-diam Si-membrane x-ray masks without supporting ribs. Also discussed are exposure configurations for achieving multilevel pattern superposition on 7.5-cm-diam wafers.
High-fidelity calibration and characterization of a spectral computed tomography system (2019)

Sandia National Laboratories has developed a model characterizing the nonlinear encoding operator of the world's first hyperspectral x-ray computed tomography (H-CT) system as a sequence of discrete-to-discrete, linear image system matrices across unique and narrow energy windows. In fields such as national security, industry, and medicine, H-CT has various applications in the non-destructive analysis of objects such as material identification, anomaly detection, and quality assurance. However, many approaches to computed tomography (CT) make gross assumptions about the image formation process to apply post-processing and reconstruction techniques that lead to inferior data, resulting in faulty measurements, assessments, and quantifications. To abate this challenge, Sandia National Laboratories has modeled the H-CT system through a set of point response functions, which can be used for calibration and anaylsis of the real-world system. This work presents the numerical method used to produce the model through the collection of data needed to describe the system; the parameterization used to compress the model; and the decompression of the model for computation. By using this linear model, large amounts of accurate synthetic H-CT data can be efficiently produced, greatly reducing the costs associated with physical H-CT scans. Furthermore, successfully approximating the encoding operator for the H-CT system enables quick assessment of H-CT behavior for various applications in high-performance reconstruction, sensitivity analysis, and machine learning.
Phosphorylation of HIV-1 gag proteins by protein kinase C. (1993)

We have demonstrated that the 17-kDa N-terminal matrix protein (p17gag) of HIV-1 Pr55gag is a substrate for protein kinase C (PKC). Phosphorylation of p17gag and Pr55gag was studied in vivo by infecting COS-7 cells with a recombinant vaccinia virus containing the HIV-1 gag-pol gene. Basal gag protein phosphorylation was inhibited up to 75% with the PKC inhibitor, H-7, and stimulated 3-4-fold with phorbol 12-myristate 13-acetate. In experiments using MCF-7 cell lines, p17gag and Pr55gag were dramatically phosphorylated only in clones with high PKC activity. Bacterially expressed and purified non-myristoylated and N-myristoylated p17gag were efficiently phosphorylated in a Ca2+ and phosphatidylserine-dependent manner by purified PKC. The N-myristoylated p17gag exhibited an apparent Km = 4 microM for PKC phosphorylation. Both in vitro and in vivo phosphorylated p17gag yielded identical V8 protease digestion phosphopeptide maps, indicating identical PKC phosphorylation sites. Phosphoamino acid analysis of the in vitro phosphorylated p17gag revealed only phosphoserine. These data are consistent with the identification of a highly conserved consensus PKC phosphorylation site motif in the HIV-1 gag protein at Ser111 and suggests that PKC phosphorylation plays an important role in gag protein function.
Ge/Si nanowire mesoscopic Josephson junctions (2006)

The controlled growth of nanowires (NWs) with dimensions comparable to the Fermi wavelengths of the charge carriers allows fundamental investigations of quantum confinement phenomena. Here, we present studies of proximity-induced superconductivity in undoped Ge/Si core/shell NW heterostructures contacted by superconducting leads. By using a top gate electrode to modulate the carrier density in the NW, the critical supercurrent can be tuned from zero to greater than 100 nA. Furthermore, discrete sub-bands form in the NW due to confinement in the radial direction, which results in stepwise increases in the critical current as a function of gate voltage. Transport measurements on these superconductor-NW-superconductor devices reveal high-order (n = 25) resonant multiple Andreev reflections, indicating that the NW channel is smooth and the charge transport is highly coherent. The ability to create and control coherent superconducting ordered states in semiconductor-superconductor hybrid nanostructures allows for new opportunities in the study of fundamental low-dimensional superconductivity.
Reverse Osmosis Compatible Chemical Foamers For Gas Well Deliquification And Production Enhancement (2010)

Abstract In times of increasing energy demand the need for more natural gas is greater than ever. To address this demand there are many drilling campaigns of coal seam gas (CSG) wells to supply the new liquefied natural gas (LNG) plants. Typically, within these wells progressive cavity pumps (PCP) are used to unload water to facilitate gas production. The produced water is then commonly processed by reverse osmosis (RO) to provide water suitable for re-use in other industries. Previously PCPs were the only feasible pumping option, due to the presence of particulates, which is a relatively expensive deliquification method. Nalco has developed an alternative artificial lift method in the form of a liquid chemical foamer. This method offers cost efficient lift that will support initial liquid unloading as well as aid liquid management to maturation, enhancing lifetime production and lowering operating expense. In addition the technology offers secondary benefits for corrosion management, improving potential asset longevity. The chemical has been demonstrated to perform in typical CSG brines and in the presence of coal fines, however the significant technology breakthrough is the compatibility with the RO membranes. Conventional foamer surfactants are incompatible and compromise safe, efficient unit operation. The laboratory and field data to demonstrate these claims is presented within. To further enhance the technology offering a total deliquification approach has been developed, combining the chemical with a patented injection system. Appropriate steps have been taken to ensure the chemical is compatible with the injection system hardware and operating conditions, and most importantly benefits from the novel atomizer valve. In comparison to standard injection valves significant gains have been recorded in the field circa. 30%. The process of well selection, hardware installation, chemical treatment and monitoring is detailed within the paper.
CREACIÓN Y FUNCIONES DEL COMITÉ CONTRA EL RACISMO Y LA DISCRIMINACIÓN (Artículos 7 y 9) (2011)

Articles 7 and 9 of the Bolivian Law against racism and all the ways of discrimination set up the National Committee Against Racism and All the Ways of Discrimination, and design the main features of this organism. This paper analyzes these articles. After that, it makes some observations on the role it plays on the Bolivian system of fight against discrimination. The paper pays attention to the Bolivian law's vision, and to the workings and the role of the European official agencies against racism and discrimination. Lastly, the paper makes some proposals wich could help to the proper functioning of the analysed agency.
Stereoscopic Photography in the Study of Particle Motion in a Blast Furnace (1954)

The paper describes the study of particle motion in front of the tuyere of a blast furnace. The normal inspection window was replaced by twin windows, and the view through these was photographed by a Kodak high-speed cine camera on a split-frame stereoscopic system. Two forms of frame-splitter were designed and used for the work. For analysis of the films, an optical method was developed operating on the projected image of a single frame. After initial adjustment, the system gives a direct indication above a plotting table of the three-dimensional position of the particle being analysed on the screen. In front of a tuyere the air blast opens a cavity in the solid mass of particles of coke, ore and limestone. By analysis of films taken the depth of this cavity was measured. Particle tracks and velocities were charted and the circulatory nature of particle motion in the cavity was also confirmed.
Characterizing and Exploiting Small-Value Memory Instructions (2014)

This paper exploits small-value locality to accelerate the execution of memory instructions. We find that small-value loads—loads with small-value operands of 8 bits or less—are common across 52 applications from the desktop, embedded, and media domains. We show that the relative occurrences of small-value loads remain fairly stable during the program execution. Moreover, we establish that the frequency of small-value loads are almost independent of compiler and input data. We then introduce the concept of small-value caches (SVC) to compactly store small-value memory words. We show that SVCs provide significant speedup and reduce the overall energy dissipation with negligible chip-area overhead.