gebhart/patrepeval huggingface dataset:
IoT control based on uplink inter-cell power control in LTE system (2014)

In LTE, the Interference over Thermal Noise (IoT) level is useful for operator to determine the link budget for coverage optimization. However, it is difficult to achieve the desired IoT operating point with the inter-cell power control solution in LTE. In this paper, a novel dynamic inter-cell power control scheme is proposed with enhanced X2 signaling to achieve the desired IoT operating point, and thus ensure the system coverage performance. The simulation results are given to verify the validity of proposed scheme.
You are what you say (2006)

Our goal is to automatically detect the functional roles that meeting participants play, as well as the expertise they bring to meetings. To perform this task, we build decision tree classifiers that use a combination of simple speech features (speech lengths and spoken keywords) extracted from the participants' speech in meetings. We show that this algorithm results in a role detection accuracy of 83% on unseen test data, where the random baseline is 33.3%. We also introduce a simple aggregation mechanism that combines evidence of the participants' expertise from multiple meetings. We show that this aggregation mechanism improves the role detection accuracy from 66.7% (when aggregating over a single meeting) to 83% (when aggregating over 5 meetings).
Unit commitment with identical units successive subproblem solving method based on Lagrangian relaxation (2002)

When the Lagrangian relaxation based methods are applied to solve power system unit commitment, the identical solutions to the subproblems associated with identical units may cause the dual solution to be far away from the optimal solution and serious solution oscillations. As a result, the quality of the feasible solution obtained may be very unsatisfactory. This issue has been long recognized as an inherent disadvantage of Lagrangian relaxation based methods. In this paper, the homogeneous solution issue is identified and analyzed through a simple example. Based on this analysis, a successive subproblem solving method is developed. The new method combines the concepts of augmented Lagrangian relaxation and surrogate subgradient to produce a good search direction at the high level. The low level subproblems including those corresponding to the identical units are solved successively so that the commitments of the identical units may not be homogeneous in the dual solution. Compared with the standard Lagrangian relaxation method, the new method can obtain better dual solutions and avoid the solution oscillations. Numerical testing shows the new method is efficient and the quality of the feasible solution is greatly improved.
Suppression of contact hypersensitivity by short-term ultraviolet irradiation: II. The role of urocanic acid. (1988)

Cis-urocanic acid (cis-UCA), produced from trans-UCA (a normal component of epidermis) by UV irradiation, suppressed cell-mediated immunological reactions in vivo and in vitro. It suppressed the development of contact hypersensitivity (CHS) when injected into mice, and it suppressed leucocyte adherence inhibition (LAI) reactions of previously sensitized lymphocytes exposed to antigen. Serum from mice injected with cis-UCA was also immunosuppressive in vitro. Normal murine spleen cells cultured with cis-UCA produced a non-dialysable factor which suppressed LAI reactivity. Trans-UCA was ineffectual in all of these systems. Both the ability of cis-UCA to induce an immunosuppressive serum factor and its ability to suppress CHS were abrogated by prior administration of cyclophosphamide, indicating that cis-UCA (normally from irradiated epidermis) stimulates T suppressor cells to produce the previously described suppressor factor in serum and the immunosuppression associated with short-term irradiation.
A Survey of Audit Pricing in Ireland (2002)

Many studies have been conducted on the market for audit services in the United States, the United Kingdom, Australia and other countries, but many countries, including Ireland, have not been studied in detail. This paper examines the audit services market in Ireland. The findings indicate broad similarities in the market for audit services in Ireland and countries previously studied. In addition to extending the results of prior studies of the audit services market to a country not previously examined in detail, this study makes an additional contribution by examining whether the large audit‐firm fee premium is a general phenomenon or is attributable to specific audit firms. The results suggest that the large audit‐firm fee premium documented in many countries may be attributable to only a few large accounting firms rather than to all large accounting firms. In this regard the market for audit services in Ireland may differ from many of the countries previously studied.
Porcine Sperm Factor Supports Activation and Development of Bovine Nuclear Transfer Embryos1 (2002)

A study was undertaken to determine whether injection of porcine sperm factors (pSF), which trigger oscillations in intracellular calcium concentration ([Ca(2+)](i)) in mammalian oocytes, could be used to activate bovine oocytes during nuclear transfer. To date, only combined treatments that induce a monotonic rise in [Ca(2+)](i) and inhibit either phosphorylation or protein synthesis have been utilized in nuclear transfer. Several doses of pSF were tested. Injection of 5 mg/ml pSF triggered [Ca(2+)](i) oscillations that resembled those associated with fertilization with respect to amplitude and periodicity, and as a result, a high percentage of oocytes underwent activation. Furthermore, this concentration of pSF supported in vitro and in vivo development up to 60-90 days of gestation, comparable to development in control nuclear transfer embryos. Nevertheless, neither activation procedure supported development as well as did fertilization. The effectiveness of pSF as an activating agent in bovine oocytes may have been compromised because pSF was unable to support oscillations past 3-5 h postinjection and a second injection was necessary to extend the [Ca(2+)](i) oscillations. Likewise, a single injection of pSF failed to trigger downregulation of the inositol 1,4,5-trisphosphate receptor 1 subtype, whereas a second injection downregulated the receptor in a manner similar to that seen in fertilized oocytes. These results demonstrate that soluble factor(s) from porcine sperm can support early development in bovine nuclear transfer embryos; however, the efficacy may be limited because of the premature cessation of the induced oscillations.
Acetylene-Containing Precursor Polymers (1980)

Abstract A significant effort has been devoted during the last 10 years to develop a route to thermally stable polymers without the evolution of volatile by-products. Most high-temperature polymers are prepared by condensation polymerization which involves the elimination of volatiles. These volatiles are responsible for severe problems encountered in the fabrication of parts, particularly thick and large components. Some success has been attained by reducing the volatile level through B-staging, which is generally accompanied by reduced resin flow and also by using an intricate bleeder system and a long cure cycle. These modifications are generally unacceptable for production-line use due to cost and reliability. A few high-temperature polymers can be processed as thermoplastics. However, the resin form is unacceptable for complex components (e.g., prepreg too boardy) and high temperature and pressure are generally required. In an attempt to circumvent these problems, work has concentrated on the development of systems which can thermally chain extend through an addition-type polymerization. A promising route developed in the late 1960s involved end-capping imide oligomers with the norbornene group which could be thermally polymerized through the unsaturation [1]. This technology became known as P13N and has since been extended to two other similar systems, PMR-15 [2] and LARC-160 [3].
Active 220- and 325-GHz Frequency Multiplier Chains in an SiGe HBT Technology (2011)

A 325-GHz ×18 frequency multiplier chain implemented in a f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">τ</sub> /f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">max</sub> = 250 GHz/380 GHz evaluation SiGe heterojunction bipolar transistor technology is presented. The chain achieves a peak output power of -3 dBm and consists of a balanced doubler driven by two cascaded tripler stages. It operates from 317 to 328 GHz with a 0-dBm 18-GHz input signal and a 1.5-W power consumption. Additionally, 220- and 325-GHz doubler breakout circuits with integrated driver amplifiers are presented. The doublers reach an output power of -1 dBm at 220 GHz and -3 dBm at 325 GHz with a power dissipation of 630 and 420 mW, respectively.
A Simple and Versatile Strategy for Rapid Color Fading and Intense Coloration of Photochromic Naphthopyran Families (2017)

Benzo-annulated chromenes, i.e., naphthopyrans, are well-known photochromic molecules that undergo photochemical ring-opening reactions to form two colored open-ring isomers, the transoid-cis and transoid-trans forms, upon light irradiation. Though the transoid-cis form returns thermally to the uncolored closed form, the fading rate of the transoid-trans form is extremely slow because of its higher thermal stability. This slow fading behavior of the transoid-trans form is responsible for the persistence of residual color for several minutes to hours, and prevents the application of such molecules to fast photoswitching materials. We have found a new simple and versatile strategy to substantially reduce the amount of the undesirable long-lived colored transoid-trans form by introducing an alkoxy group at the 1-position of azino-fused chromenes, i.e., 8H-pyranoquinazolines. The alkoxy group effectively reduces the formation of the transoid-trans form due to C-H···O intramolecular hydrogen bonding in the transoid-cis form. Moreover, the introduction of a condensed aromatic ring at the 3-position was found to be effective to increase the photosensitivity of the ring-opening reaction. This strategy can also be applied for naphthopyran derivatives and is useful for the development of fast photoresponsive photochromic lenses and fast photoswitching applications such as dynamic holographic materials and molecular actuators.
Ablation of ceramide synthase 2 strongly affects biophysical properties of membranes (2012)

Little is known about the effects of altering sphingolipid (SL) acyl chain structure and composition on the biophysical properties of biological membranes. We explored the biophysical consequences of depleting very long acyl chain (VLC) SLs in membranes prepared from lipid fractions isolated from a ceramide synthase 2 (CerS2)-null mouse, which is unable to synthesize C22-C24 ceramides. We demonstrate that ablation of CerS2 has different effects on liver and brain, causing a significant alteration in the fluidity of the membrane and affecting the type and/or extent of the phases present in the membrane. These changes are a consequence of the depletion of VLC and unsaturated SLs, which occurs to a different extent in liver and brain. In addition, ablation of CerS2 causes changes in intrinsic membrane curvature, leading to strong morphological alterations that promote vesicle adhesion, membrane fusion, and tubule formation. Together, these results show that depletion of VLC-SLs strongly affects membrane biophysical properties, which may compromise cellular processes that critically depend on membrane structure, such as trafficking and sorting.
The <i>Saccharomyces cerevisiae MLH</i> <i>3</i> gene functions in MSH3-dependent suppression of frameshift mutations (1998)

The Saccharomyces cerevisiae genome encodes four MutL homologs. Of these, MLH1 and PMS1 are known to act in the MSH2-dependent pathway that repairs DNA mismatches. We have investigated the role of MLH3 in mismatch repair. Mutations in MLH3 increased the rate of reversion of the hom3-10 allele by increasing the rate of deletion of a single T in a run of 7 Ts. Combination of mutations in MLH3 and MSH6 caused a synergistic increase in the hom3-10 reversion rate, whereas the hom3-10 reversion rate in an mlh3 msh3 double mutant was the same as in the respective single mutants. Similar results were observed when the accumulation of mutations at frameshift hot spots in the LYS2 gene was analyzed, although mutation of MLH3 did not cause the same extent of affect at every LYS2 frameshift hot spot. MLH3 interacted with MLH1 in a two-hybrid system. These data are consistent with the idea that a proportion of the repair of specific insertion/deletion mispairs by the MSH3-dependent mismatch repair pathway uses a heterodimeric MLH1-MLH3 complex in place of the MLH1-PMS1 complex.
Castor oil: new lessons from an ancient oil (1998)

Castor oil, from Ricinus communis, has been used since ancient times as a safe and reliable laxative. The pharmacologically active molecule in the oil is ricinoleic acid. This hydroxylated, long-chain fatty acid has multiple effects on the intestinal mucosa, resulting in fluid secretion. Early studies indicated that the mucosal effects were due to enteritis or interference with cellular metabolism. Later studies revealed that the fatty acid could increase mucosal permeability and cause cytotoxicity, associated with release of eicosanoids, platelet activating factor, other autacoids and nitric oxide. In addition, ricinoleic acid disrupts normal intestinal motility. The combination of these effects on the mucosa and smooth muscle of the gut account for its laxative action. © 1998 John Wiley & Sons, Ltd.
Recomposition (1998)

building sofivare from the Perspectiveof the coordination Design and development work have become increasingly interesting to CSCW researchers. This paper introduces a new perspective for extimg that work. decomposition. Decomposition focuses on the activities required to coordinate the assembly of an artifacL Using examples drawn from a study of three software development organizations, I show how decomposition is a form of articulation work I describe how that articulation work influences the product produce~and how the product itseK influences the coordination required-I discuss the implications of a decomposition view for CSCW research.
Mechanism of the decomposition of silacyclobutane to silylene and propene (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMechanism of the decomposition of silacyclobutane to silylene and propeneThomas J. Barton and Nolan TillmanCite this: J. Am. Chem. Soc. 1987, 109, 22, 6711–6716Publication Date (Print):October 1, 1987Publication History Published online1 May 2002Published inissue 1 October 1987https://pubs.acs.org/doi/10.1021/ja00256a025https://doi.org/10.1021/ja00256a025research-articleACS PublicationsRequest reuse permissionsArticle Views1120Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Impaired Antibody Responses to Pneumococcal Polysaccharide in Elderly Patients with Low Serum Vitamin B<sub>12</sub> Levels (1996)

Patients with low vitamin B12 levels had impaired antibody responses to pneumococcal vaccine. Further study is necessary to determine whether treatment with vitamin B12 can enhance specific immunoglobulin synthesis and improve the clinical efficacy of the pneumococcal vaccine in patients with low vitamin B12 levels.
Alliance of Proteomics and Genomics to Unravel the Specificities of Sahara Bacterium Deinococcus deserti (2009)

To better understand adaptation to harsh conditions encountered in hot arid deserts, we report the first complete genome sequence and proteome analysis of a bacterium, Deinococcus deserti VCD115, isolated from Sahara surface sand. Its genome consists of a 2.8-Mb chromosome and three large plasmids of 324 kb, 314 kb, and 396 kb. Accurate primary genome annotation of its 3,455 genes was guided by extensive proteome shotgun analysis. From the large corpus of MS/MS spectra recorded, 1,348 proteins were uncovered and semiquantified by spectral counting. Among the highly detected proteins are several orphans and Deinococcus-specific proteins of unknown function. The alliance of proteomics and genomics high-throughput techniques allowed identification of 15 unpredicted genes and, surprisingly, reversal of incorrectly predicted orientation of 11 genes. Reversal of orientation of two Deinococcus-specific radiation-induced genes, ddrC and ddrH, and identification in D. deserti of supplementary genes involved in manganese import extend our knowledge of the radiotolerance toolbox of Deinococcaceae. Additional genes involved in nutrient import and in DNA repair (i.e., two extra recA, three translesion DNA polymerases, a photolyase) were also identified and found to be expressed under standard growth conditions, and, for these DNA repair genes, after exposure of the cells to UV. The supplementary nutrient import and DNA repair genes are likely important for survival and adaptation of D. deserti to its nutrient-poor, dry, and UV-exposed extreme environment.
Additive Dose Response Models: Explicit Formulation and the Loewe Additivity Consistency Condition (2018)

High-throughput techniques allow for massive screening of drug combinations. To find combinations that exhibit an interaction effect, one filters for promising compound combinations by comparing to a response without interaction. A common principle for no interaction is Loewe Additivity which is based on the assumption that no compound interacts with itself and that two doses from different compounds having the same effect are equivalent. It then should not matter whether a component is replaced by the other or vice versa. We call this assumption the Loewe Additivity Consistency Condition (LACC). We derive explicit and implicit null reference models from the Loewe Additivity principle that are equivalent when the LACC holds. Of these two formulations, the implicit formulation is the known General Isobole Equation (Loewe, 1928), whereas the explicit one is the novel contribution. The LACC is violated in a significant number of cases. In this scenario the models make different predictions. We analyze two data sets of drug screening that are non-interactive (Cokol et al., 2011; Yadav et al., 2015) and show that the LACC is mostly violated and Loewe Additivity not defined. Further, we compare the measurements of the non-interactive cases of both data sets to the theoretical null reference models in terms of bias and mean squared error. We demonstrate that the explicit formulation of the null reference model leads to smaller mean squared errors than the implicit one and is much faster to compute.
Microstructure and Overvoltage Characteristics of the Anode for Solid Oxide Fuel Cells (1993)

The drip-pyrolysis process with YSZ sol was developed for preparing the anode powder. The use of this process enables high dispersibility of YSZ in Ni-YSZ anode. Furthermore , application of (Ni, Mg) O-YSZ fabricated by this process to the anode material has succeeded in improving overvoltage characteristics of the anode. The electrochemical overvoltage η of the (Ni, Mg) O-YSZ anode was 20mV at a current density of 300 mA/cm2, much smaller than that of the Ni-YSZ anode. The (Ni, Mg) O-YSZ anode was characterized by finely porous Ni particles and very different from the Ni-YSZ anode in microstructure. This structure contributes to improving the overvoltage characteristics.
Quantifying Co-Oligomer Formation by α-Synuclein (2018)

Small oligomers of the protein α-synuclein (αS) are highly cytotoxic species associated with Parkinson's disease (PD). In addition, αS can form co-aggregates with its mutational variants and with other proteins such as amyloid-β (Aβ) and tau, which are implicated in Alzheimer's disease. The processes of self-oligomerization and co-oligomerization of αS are, however, challenging to study quantitatively. Here, we have utilized single-molecule techniques to measure the equilibrium populations of oligomers formed in vitro by mixtures of wild-type αS with its mutational variants and with Aβ40, Aβ42, and a fragment of tau. Using a statistical mechanical model, we find that co-oligomer formation is generally more favorable than self-oligomer formation at equilibrium. Furthermore, self-oligomers more potently disrupt lipid membranes than do co-oligomers. However, this difference is sometimes outweighed by the greater formation propensity of co-oligomers when multiple proteins coexist. Our results suggest that co-oligomer formation may be important in PD and related neurodegenerative diseases.
Polyhalogenated BEDT-TTF through chlorination (SO2Cl2, Cl2) and fluorination (®Selectfluor, XeF2) of 5,6-dihydro[1,3]dithiolo[4,5-b][1,4]dithiin-2-one (2001)

The electrophilic halogenation of the ethylenic bridge in the 5,6-dihydro[1,3]dithiolo[4,5-b][1,4]dithiin-2-one (1) with SO2Cl2, ®Selectfluor [1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate)] or XeF2 affords the corresponding monochloro, 1,2-dichloro and monofluoro derivatives 2, 3 and 6, respectively. Reaction with Cl2 gives rise to a pentachloro derivative (5) with syn-Cl2 addition across the unsaturated double bond of 1 characterised by single crystal X-ray diffraction. Homocoupling of 2, 3 or 6 in P(OMe)3 affords the corresponding dichloro, tetrachloro and difluoro BEDT-TTFs 8, 9 and 10, respectively, whose electrochemical characteristics show the electron-withdrawing nature of the halogen substituents present on the ethylenic bridge. Electrocrystallisation of 9 in the presence of (n-Bu4N)2(Mo6Cl14) affords a mixed-valence salt formulated as [9]3[Mo6Cl14], whose X-ray crystal structure has been determined and analysed.
Subjective effects of double gloves on surgical performance. (1996)

This randomised trial compared single gloves with combinations of double gloves to determine the subjective effects on comfort, sensitivity and dexterity in 32 surgeons. Glove perforation rates were also compared. Single gloves of the surgeon's normal size (method A) were used as control. Double gloves were worn in three different ways, selected randomly: normal gloves inside and gloves one-half size larger outside (method B); the larger gloves inside and the normal gloves outside (method C); and lastly, two pairs of gloves of normal size (method D). Double gloves by all three methods significantly protected against needle perforation of the inner gloves when compared with single gloves, but also significantly impaired comfort, sensitivity and dexterity. When the three types of double gloving were compared, there appeared to be advantages for method C for all modalities, but the differences did not reach statistical significance; also, more surgeons expressed a preference for method C. Perforation of the inner gloves was significantly less for double gloves than for single gloves. We conclude that double gloves often protect the surgeon against needle perforations, but are felt to impair comfort, sensitivity and dexterity.