gebhart/patrepeval huggingface dataset:
Computerized colour vision testing. (1994)

There are many advantages to the computerization of colour vision tests. However, previous computerized colour vision tests have involved equipment and methods not commonly used in clinical practice. We created computer emulations of the City University Colour Vision Test (CUT), Ishihara plates and American Optical Hardy-Rand-Rittler (AO-HRR) plates using a commonly available 24-bit colour Macintosh computer. Our colour monitor was calibrated to standard display white (D65), and colour plates were imaged with a colour scanner. The computerized colour images were compared with the standard test plates in a sample of 21 subjects with normal colour vision, 10 patients with congenital red-green defect and 1 patient with an acquired mixed colour defect. The computer images of the three tests correlated well with their conventional counterparts on kappa statistic analysis (p < 0.001), for both the colour normal and colour defective groups. We conclude that our computer emulations of the CUT, Ishihara and AO-HRR tests screen subjects with normal colour vision with high specificity and delineate congenital colour defects with a sensitivity comparable to that of their conventional counterparts.
Manejo terapéutico de la migraña (2009)

We can summarize the main objectives of the treatment of the migraine’s acute frame in: to liberate the patient of the painful frame, to avoid the recurrence of the pain, to reinstall the patient in his daily activities, to lengthen the period free of migraine crisis. The treatment of the patient with migraine depends on the duration and severity of the headache; the associated symptoms, the grade of inability and the initial answer to the therapy. Diverse clinical investigations studying the treatment of acute migraine takes as parameter to evaluate the therapeutic answer the proportion of patients in who the moderate or severe headache passes to light or disappears in the two following hours to the medication
Structural requirements for intracellular targeting of SP-C proprotein (1999)

Rat surfactant protein (SP) C is synthesized as a 194-amino acid proprotein that is proteolytically processed to a 35-amino acid mature form in subcellular compartments distal to the medial Golgi compartment. To identify domains of SP-C proprotein (proSP-C) necessary for endoplasmic reticulum translocation and for targeting to cytosolic processing compartments, we characterized expression patterns of heterologous SP-C fusion proteins in A549 lung epithelial cells and in the rat pheochromocytoma cell line PC-12. cDNA constructs were produced; these constructs encoded fusion proteins consisting of enhanced green fluorescent protein (EGFP) and wild-type proSP-C (EGFP/SP-C(1-194)), mature SP-C (EGFP/SP-C(24-59)), or progressive deletions of the NH(2)- or COOH-terminal flanking domains. By fluorescence microscopy, EGFP/SP-C(1-194) transfected into A549 cells was translocated and expressed in acidic cytoplasmic vesicles. By deletional analysis, a functional signal peptide was mapped to the domain Phe(24) to His(59), whereas a motif for targeting to cytosolic vesicular compartments was localized to the NH(2) flanking domain Met(10) to Gln(23). Truncations of the distal COOH terminus were retained in the endoplasmic reticulum/Golgi compartment; however, the COOH flanking region alone was insufficient for targeting. In PC-12 cells, EGFP/SP-C(1-194) was expressed in peripheral cytosolic vesicles, whereas EGFP/SP-C(24-194) and EGFP/SP-C(24-59) were each translocated but not targeted. We conclude that two domains in the proSP-C sequence are required for targeting: mature SP-C (Phe(24) to Leu(58)) contains a functional signal sequence active in epithelial and nonepithelial cells, whereas Met(10) to Gln(23), but not the COOH flanking peptide, is required for targeting to late vesicular compartments.
Simultaneous motion estimation and image reconstruction from gated data (2003)

In this paper we investigate the problem of simultaneously estimating the non-rigid motion vector field and the emission images in dynamic medical imaging procedures, such as gated cardiac ECT. We consider the case of two datasets, which, for instance, may be applied to the problem of determining the motion and emission intensities of the myocardium between end-diastole and end-systole gated cardiac data. Our method is based on minimizing an objective function consisting of a maximum likelihood image reconstruction term; the strain energy of an elastic material; and an image matching term that ensures a measure of agreement between the reference and deformed gated images. Minimization is achieved by a two-step iterative algorithm which alternately updates the motion vector field and the gated images. Simulations using exact and noisy datasets for a simple 2D phantom demonstrate the feasibility of the proposed method.
Octave-spanning super-continuum from a silica photonic crystal fiber pumped by a 386 MHz Yb:fiber laser (2012)

We report octave-spanning super-continuum generation in a silica photonic crystal fiber (PCF) pumped by a compact, efficient, mode-locked all-normal dispersion Yb:fiber laser. The laser achieved 45% optical-to-optical efficiency by using an optimized resonator design, producing chirped 750 fs pulses with a repetition rate of 386 MHz and an average power of 605 mW. The chirped pulses were compressed to 110 fs with a loss of only 4% by using multiple reflections on a pair of Gires-Tournois interferometer mirrors, yielding an average power of up to 580 mW. The corresponding peak power was 13.7 kW and produced a super-continuum spectrum spanning from 696-1392 nm.
Determination of Chloride Content in Compounds and in Solutions of High Bromide to Chloride Concentration Ratios (1971)

Abstract A method is described for the determination of chloride in compounds and in solutions of high bromide to chloride molar ratios (up to 6300:1). Solutions were boiled briefly with nitric acid to oxidize the bulk concentration of bromide ion to bromine gas which was then flushed with air. Chloride ion was titrated potentiometrically with silver nitrate in 80% i‐propanol‐water medium using a silver‐silver bromide indicator electrode and a chloride‐free reference electrode. Details of the potentiometric techniques peculiar to these titrations are described. The method was successfully applied to the determination of the chloride content of commercially available bromide reagents.
Speech coding using waveform matching based on LPC residual phase equalization (2002)

A speech analysis-synthesis method based on linear predictive coding (LPC) residual phase equalization is presented for low-bit- rate natural sounding speech coding. In this method, the phase-equalized LPC residual signal is represented as the output of the quasi-periodic impulsive excitation to an all-zero filter, which captures harmonic deviation in the residual spectrum which has not been compensated for by LPC inverse filtering of the input speech signal. The impulsive excitation is specified by the instantaneous pitch excitation instant and amplitude. A procedure is presented to determine the excitation parameters and the all-zero filter using a waveform matching criterion. The coder performance is studied objectively and subjectively with a focus on the potential of the excitation model to produce high-quality speech. A speech coder designed for bit rates lower than 4.8 kb/s is discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A RISC architecture with two-size, overlapping register windows (1988)

The issues involved in designing multiple-register window schemes are examined, and fixed-size, variable-size and two-size window organizations are discussed. These three multiple-register approaches are compared. A detailed example is presented, showing that the proposed two-size register window scheme has significant advantages over both fixed-size and variable-size schemes. A prototype design is presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Personal History (2002)

In the 1970s, urban geography in the United States was primarily concerned with understanding the development of our system of cities and also with discerning and modeling patterns in the internal structure of the metropolitan area. Hypothesis testing and the application of some rather complex multivariate statistics to census and other survey data were common. This paper outlines the author's personal history in this subfield through this decade.
Clinical Radiation Management for Fluoroscopically Guided Interventional Procedures (2010)

The primary goal of radiation management in interventional radiology is to minimize the unnecessary use of radiation. Clinical radiation management minimizes radiation risk to the patient without increasing other risks, such as procedural risks. A number of factors are considered when estimating the likelihood and severity of patient radiation effects. These include demographic factors, medical history factors, and procedure factors. Important aspects of the patient's medical history include coexisting diseases and genetic factors, medication use, radiation history, and pregnancy. As appropriate, these are evaluated as part of the preprocedure patient evaluation; radiation risk to the patient is considered along with other procedural risks. Dose optimization is possible through appropriate use of the basic features of interventional fluoroscopic equipment and intelligent use of dose-reducing technology. For all fluoroscopically guided interventional procedures, it is good practice to monitor radiation dose throughout the procedure and record it in the patient's medical record. Patients who have received a clinically significant radiation dose should be followed up after the procedure for possible deterministic effects. The authors recommend including radiation management as part of the departmental quality assurance program.
Retention Rates on RBANS Memory Subtests in Elderly Adults (2008)

Identification of memory impairment is important for neuropsychological diagnostic and research applications, and retention rates on verbal and visual memory tests can provide useful information when characterizing a variety of neurological and psychiatric disorders. Although the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) is becoming a popular screening battery for cognitive functions, normative data on retention rates are not available. The retention rates of verbal and visual material were evaluated in a sample of clinical patients (n = 109) compared to a healthy control group (n = 718). Individual subtest retention rates were converted to age-corrected scaled scores based on the cumulative distribution of raw scores obtained by an elderly community-dwelling sample. Compared with the healthy normative sample, the percent retention found for the clinical group was significantly lower on all 3 RBANS memory subtests. These preliminary data suggest that retention rates of the RBANS memory subtests may add to the clinical utility of this test as a neuropsychological diagnostic and research tool.
Key Technologies for THz Wireless Link by Silicon CMOS Integrated Circuits (2018)

In terahertz-band communication using ultra-high frequencies, compound semiconductors with superior high-frequency performance have been used for research to date. Terahertz communication using the 300 GHz band has nonetheless attracted attention based on the expectation that an unallocated frequency band exceeding 275 GHz can be used for communication in the future. Research into wireless transceivers using BiCMOS integrated circuits with silicon germanium transistors and advanced miniaturized CMOS integrated circuits has increased in this 300 GHz band. In this paper, we will outline the terahertz communication technology using silicon integrated circuits available from mass production, and discuss its applications and future.
NF-&kappa;B as a Target for Modulating Inflammatory Responses (2012)

The inflammatory response is of major importance in host defence, but is involved in all acute and chronic diseases. Multiple inflammatory cells and molecules are involved. Among the latter, the Nuclear Factor -κB (NF-κB) has been found to be most important and present in all cell types. NF-B regulates the expression of a large number of genes involved in inflammation. NF-κB plays a key role in the orchestration of the multifaceted inflammatory response, not only in the first pro-inflammatory phase, but also later in the regulation of the resolution of inflammation, when anti-inflammatory genes are expressed and apoptosis is induced. The review describes NF-κB and its two pathways: the canonical, mediated by the p65 and p50 subunits, and the non-canonical, mediated by the subunits RelB, p52 and p50. The relevance of the kinases and interactions leading to NF-κB activation is considered in different primary cells (i.e. macrophages, dendritic cells, fibroblasts, cells from inflammatory tissues), together with the response induced and the ligand involved. Then we overview the different steps to NF-B activation that can be targeted (IKKs, IκBα or NF-κB subunits themselves) with various technologies available i.e. small molecules peptides or nucleic acids. A rationale is provided for possible targets to consider, in the light that NF-κB signaling pathways regulates both pro-inflammatory and anti-inflammatory responses. The possibility of using NF-κB targeted dendritic cells in immunotherapy is considered.
3‐Äthoxycarbonyl‐cinchoninsäureamide aus Isatinen und 3‐Amino‐acrylsäure‐äthylestern (1971)

Abstract Substituierte Isatine reagieren mit 3‐Amino‐acrylsäure‐äthylestern unter Ringerweiterung zu 3‐Äthoxycarbonyl‐cinchoninsäureamiden.
Optimization of the settings of multiphase induction heating system (2012)

This paper deals with the setting parameter optimization procedure for a multi-phase induction heating system considering transverse flux heating. This system is able to achieve uniform static heating of different thin/size metal pieces without movable inductor parts, yokes or magnetic screens. The goal is reached by the predetermination of the induced power density distribution using an optimization procedure that leads to the required inductor supplying currents. The purpose of the paper is to describe the optimization program with the different solution obtained and to show that some compromise must be done between the accuracy of the temperature profile and the energy consumption.
Tissue engineering of cardiac valve prostheses I: development and histological characterization of an acellular porcine scaffold. (2002)

Protocols utilizing SDS or sodium deoxycholate were successful for leaflet decellularization, and histological analysis showed that the major structural components of the valve matrix had been maintained. These methods are being developed further with a view to reseeding with autologous cells to produce tissue-engineered solutions for clinical implantation.
Mannose binding lectin plays a crucial role in innate immunity against yeast by enhanced complement activation and enhanced uptake of polymorphonuclear cells (2008)

Our results suggest that MBL plays a crucial role in the innate immunity against infections caused by yeast by increasing uptake by PMN.
Helium as a Carrier Gas in Humidification Dehumidification Desalination Systems (2011)

A promising technology for small scale seawater desalination is the humidification dehumidification (HDH) system. This technology has been widely investigated in recent years. Since existing HDH systems have very high specific energy consumption, the authors have previously invented several ways to increase the energy efficiency of these systems. Even for these relatively higher efficiency systems the dehumidifier is expected to be large, owing to the large thermal resistance associated with the presence of non-condensable carrier gas (air) in the system. In this manuscript, we demonstrate that changing the carrier gas from air to helium a potential solution to this problem. In addition, the energy performance of a brine heated HDH system using helium relative to those using air is analysed in detail through well established on-design models for the components in the system.
Unidirectional Broadband Light Emission from Supported Plasmonic Nanowires (2011)

Metal nanowires are thought to become key elements in future nanophotonics applications. Here we show that single crystal silver nanowires supported on a dielectric interface behave similar to broadband unidirectional antennas for visible light. The degree of directionality can be controlled through the nanowire radius and its dielectric environment and the effect can be interpreted in terms of so-called leakage radiation from surface plasmons propagating in a single direction along a wire. We measure a forward-to-backward emission ratio exceeding 15 dB and an angular spread of 4° for wires with radii of the order 150 nm on glass in air. These findings could pave the way for development of metal nanowires as subwavelength directors of light in solar, sensor, and spectroscopy applications.
Amplification of c‐<i>myc</i> and c‐<i>erb</i>B‐2 proto‐oncogenes in human solid tumors: Frequency and clinical significance (1989)

Molecular probes for cellular proto-oncogenes have recently been extensively used in order to search for functional and structural alterations in tumor tissues. Variable, and sometimes contradictory, results have been obtained regarding the frequency and clinical significance of amplification of the c-myc and c-erbB-2 proto-oncogenes in different series of human solid tumors. We addressed this question by performing Southern blotting analysis on 131 primary adult solid tumors of various tissues and 5 metastases of unknown origin, using molecular probes for both genes. Amplification of c-myc was found in 5 of the primary tumors, and amplification of c-erbB-2 in 5 others. In 2 tumors of the latter group, the c-erbB-2 gene was also rearranged. The distribution of these 10 tumors with regard to clinical stage and course of the disease did not point to an association between the amplification events and specific stage or prognosis. We concluded that, in this series, the amplification of both proto-oncogenes was occasional and was not a prognostic marker.
Significant Coronary Artery Stenosis: Comparison on Per-Patient and Per-Vessel or Per-Segment Basis at 64-Section CT Angiography (2007)

On a per-patient basis, 64-section multi-detector row CT coronary angiography enables the diagnosis of significant (>or=50%) stenosis in CAD with an accuracy of 89%. On a per-segment and per-vessel basis, diagnostic accuracy is still impaired, primarily by limited spatial resolution.
Intelligent database for the SOA using BPEL (2011)

Service Oriented Architecture (SOA) reuses services to automate a business process using a standard interface and message structure. Standards include the Web Service Description Language (WSDL) file for service interface definition and XML Schema Documents (XSD) for message structure definition. Web services uses the standardization where services are invoked using SOAP over HTTP. BPEL is an orchestration language used to describe the execution logic of Web services by defining their control flow. Choreographies are used to capture collaborations between multiple business partners from a global perspective. SOA can generate the result service in XML language. In this paper XML output of SOA is analyzed using the BPEL standardization. Result is sequenced with choreographic rules. Proposed system in this paper suggests the storage of XML data into the database structure with BPEL business logic and choreography. Using BPEL, business process can be integrated into series of discrete services with an end-to-end process flow. This integration reduces process cost and complexity. A choreography model describes multiparty collaboration and focuses on message exchange; each Web service involved in a choreography knows exactly when to execute its operations and with whom to interact. From this intelligent database; result will be easy for retrieval which is the integration of the heterogeneous database integration.
Growth and properties of an LiNbO <sub>3</sub> film on sapphire with an LiNbO <sub>3</sub> buffer layer (1987)

A lithium niobate (LiNbO3) epitaxial film has been grown by magnetron RF sputtering. It was grown on a sapphire substrate with a predeposited and annealed LiNbO3 buffer layer. The effects of a buffer layer on growth-film properties were studied by physical analysis, including X-ray diffraction, reflection high-energy electron diffraction and scanning electron microscopy.
Modern Communications Jamming Principles and Techniques (2003)

This newly revised and greatly expanded edition of the popular Artech House book, Modern Communications Jamming Principles and Techniques, provides an up-to-date, exhaustive treatment of the techniques and methods available to create countermeasures against anti-jam, over-the-air communications. The Second Edition features a wealth of new material on urban warfare, including a computer simulation of EW architecture alternatives for land-based forces based on urban constraints. The new edition also includes an expanded section on time-hopped spread spectrum communications, more details on modern communication system technologies such as CDMA and OFDM, and an in-depth discussion on sources of urban noise. This practical resource is focused on showing you how to design and build jammers specifically targeted at spread spectrum, anti-jam communications. Moreover, you find assistance in evaluating the expected performance of jamming systems against modern communications systems, and discover the best waveform to use to counter communication systems designed to be effective in jamming environments. While mathematical derivations in general are avoided, the book presents error rate performance equations for most modern digital anti-jam communication systems.
Sentinel lymph node biopsy in impalpable breast cancer (2001)

Sentinel lymph node biopsy has been investigated using combined radioactive colloid and supra vital blue dye in 27 patients with impalpable breast cancers. Sentinel nodes were identified in 25 cases (93%). Seven patients had involved nodes of whom all had a positive sentinel node. Sentinel node biopsy is ideally suited for use in impalpable breast cancers.
Enantioselective deprotonation of 4-tert-butylcyclohexanone by conformationally constrained chiral lithium amide bases (1999)

Conformationally rigid chiral lithium amides based on a tetrahydroisoquinoline motif have been prepared bearing a range of substituents at C1 and C3. These bases were tested in the asymmetric deprotonation reaction of 4-tert-butylcyclohexanone. Although the 1-substituted tetrahydroisoquinolines gave low enantioselectivity, the chiral bases containing a nitrogen heterocycle at C3 were found to induce high enantioselectivity (81% ee) in the presence of HMPA.