gebhart/patrepeval huggingface dataset:
Stability and Fairness Issues in Layered Multicast (1999)

Layered multicast is a promising technique for broadcasting adaptive-quality video to heterogeneous receivers. Past evaluation of layered multicast protocols has focused on the effectiveness of determining the maximal number of layers that can be delivered to each receiver. Unfortunately, this is only a partial metric and does not capture all aspects of the “viewing experience”. This paper extends past analysis by investigating stability of layered multicast schemes and the related issues of fairness and scalability. Our study is motivated by the desire to transmit small-scale TV broadcasts (hundreds or thousands of viewers) over IP-based networks with heterogeneous receivers. Although users are aware of their physical bandwidth limitations, they will still expect TV-like characteristics of their video such as consistent quality (i.e., stability). Our results shows that Receiver-Driven Layered Multicast (RLM) exhibits significant and persistent instability. Previous work also raises fairness as a potential problem with RLM. We show that with CBR traffic RLM can be arbitrarily unfair, but with VBR traffic, RLM provided better fairness than we anticipated. Our analysis of stability in RLM prompted us to question RLM’s ability to select the optimum number layers for a non-shared access link. We show that RLM is very conservative in its choice resulting in low link utilization. 1
Using Crowd-Source Based Features from Social Media and Conventional Features to Predict the Movies Popularity (2015)

Predicting the success of movies has been of interest to economists and investors (media and production houses) as well as predictive analysts. A number of attributes such as cast, genre, budget, production house, PG rating affect the popularity of a movie. Social media such as Twitter, YouTube etc. are major platforms where people can share their views about the movies. This paper describes experiments in predictive analysis using machine learning algorithms on both conventional features, collected from movies databases on Web as well as social media features (text comments on YouTube, Tweets). The results demonstrate that the sentiments harnessed from social media and other social media features can predict the success with more accuracy than that of using conventional features. We achieved best value of 77% and 61% using selected social media features for Rating and Income prediction respectively, whereas selected conventional features gave results of 76.2% and 52% respectively. More it was found that the blend of both types of attributes (conventional and those collected from social media) can outperform the existing approaches in this domain.
Application of the LMS adaptive filter to improve speech communication in the presence of noise (2005)

A major complaint of individuals with normal hearing and hearing impairment is a reduced ability to understand speech in a noisy environment. An adaptive LMS filter was employed to process speech in signal-to-noise ratios (S/N) varying from -8 to +12 dB. The filter configuration is commonly called noise cancellation. Intelligibility measures were obtained on normal and hearing impaired individuals using CID-W22 word lists. For the normal subjects mean intelligibility scores unprocessed were near zero for the S/N ratios -8, -4, and 0 dB and increased from 30 to 50% for the same S/N ratios when processed. For S/N ratios of +4 through +12, mean intelligibility scores prior to filtering ranged from 24 to 46%; after filtering, the scores improved from 67 to 75% i.e., within 7% of the nolse-free sound-field recordings. Preliminary data for the hearing impaired showed the same pattern with their improvement also approaching the scores obtained with no noise present in the sound field.
A LSTM-based method for stock returns prediction: A case study of China stock market (2015)

The presented paper modeled and predicted China stock returns using LSTM. The historical data of China stock market were transformed into 30-days-long sequences with 10 learning features and 3-day earning rate labeling. The model was fitted by training on 900000 sequences and tested using the other 311361 sequences. Compared with random prediction method, our LSTM model improved the accuracy of stock returns prediction from 14.3% to 27.2%. The efforts demonstrated the power of LSTM in stock market prediction in China, which is mechanical yet much more unpredictable.
Hepatitis E in pregnancy (2004)

One-third of the pregnant women with HEV infection had a severe form of hepatitis in the third trimester of pregnancy, i.e. FHF. Hepatitis E in pregnancy is associated with high rates of preterm labor and mortality.
Transient Interruption of Contrast on CT Pulmonary Angiography (2007)

Transient interruption of contrast of the pulmonary arteries represents a flow-related phenomenon associated with an increased IVC contribution to the right side of the heart.
Cervical laminectomy for myelopathy (1996)

This article briefly describes the clinical entity of cervical spondylotic myelopathy along with the differential diagnosis and preoperative diagnostic evaluation. Surgical indications and operative technique for posterior cervical laminectomy are discussed in detail. Outcomes and complications are discussed and comparisons are made with alternative decompressive techniques. Specific indications in which posterior cervical laminectomy is the treatment of choice are highlighted.
<i>Corynebacterium glutamicum</i>Utilizes both Transsulfuration and Direct Sulfhydrylation Pathways for Methionine Biosynthesis (2002)

A direct sulfhydrylation pathway for methionine biosynthesis in Corynebacterium glutamicum was found. The pathway was catalyzed by metY encoding O-acetylhomoserine sulfhydrylase. The gene metY, located immediately upstream of metA, was found to encode a protein of 437 amino acids with a deduced molecular mass of 46,751 Da. In accordance with DNA and protein sequence data, the introduction of metY into C. glutamicum resulted in the accumulation of a 47-kDa protein in the cells and a 30-fold increase in O-acetylhomoserine sulfhydrylase activity, showing the efficient expression of the cloned gene. Although disruption of the metB gene, which encodes cystathionine gamma-synthase catalyzing the transsulfuration pathway of methionine biosynthesis, or the metY gene was not enough to lead to methionine auxotrophy, an additional mutation in the metY or the metB gene resulted in methionine auxotrophy. The growth pattern of the metY mutant strain was identical to that of the metB mutant strain, suggesting that both methionine biosynthetic pathways function equally well. In addition, an Escherichia coli metB mutant could be complemented by transformation of the strain with a DNA fragment carrying corynebacterial metY and metA genes. These data clearly show that C. glutamicum utilizes both transsulfuration and direct sulfhydrylation pathways for methionine biosynthesis. Although metY and metA are in close proximity to one another, separated by 143 bp on the chromosome, deletion analysis suggests that they are expressed independently. As with metA, methionine could also repress the expression of metY. The repression was also observed with metB, but the degree of repression was more severe with metY, which shows almost complete repression at 0.5 mM methionine in minimal medium. The data suggest a physiologically distinctive role of the direct sulfhydrylation pathway in C. glutamicum.
Sequence variation and phylogenetic analysis of envelope glycoprotein of hepatitis G virus. (1997)

A transfusion-transmissible agent provisionally designated hepatitis G virus (HGV) was recently identified. In this study, we examined the variability of the HGV genome by analysing sequences in the putative envelope region from 72 isolates obtained from diverse geographical sources. The 1561 nucleotide sequence of the E1/E2/NS2a region of HGV was determined from 12 isolates, and compared with three published sequences. The most variability was observed in 400 nucleotides at the N terminus of E2. We next analysed this 400 nucleotide envelope variable region (EV) from an additional 60 HGV isolates. This sequence varied considerably among the 75 isolates, with overall identity ranging from 79.3% to 99.5% at the nucleotide level, and from 83.5% to 100% at the amino acid level. However, hypervariable regions were not identified. Phylogenetic analyses indicated that the 75 HGV isolates belong to a single genotype. A single-tier distribution of evolutionary distances was observed among the 15 E1/E2/NS2a sequences and the 75 EV sequences. In contrast, 11 isolates of HCV were analysed and showed a three-tiered distribution, representing genotypes, subtypes, and isolates. The 75 isolates of HGV fell into four clusters on the phylogenetic tree. Tight geographical clustering was observed among the HGV isolates from Japan and Korea.
Fabrication and Characterization of a Hydroquinone-Functionalized Polypyrrole Thin-Film pH Sensor (1996)

The physical and chemical properties of polypyrrole (PPy) derivatized at the 3-position with dimethoxybenzyl and dihydroxybenzyl functionalities via a novel high-yield pathway were evaluated for pH response. The monomers were electrochemically polymerized with perchlorate dopant in a propylene carbonate electrolyte solution. The potentiometric characteristics of the resulting films show a sub-Nernstian response of 46.0 mV pH-1 (25 °C); a detection limit of 1 × 10-10 mol dm-1; potential drift of ±1.9 mV and a low hysteresis with Δslope = ±1.9 mV pH-1. X-ray photoelectron spectroscopy (XPS) shows a reduction in the carbon 1s and chlorine 2p photoelectron peaks widths for functionalized PPy in comparison with the PPy indicating presence of β-carbon substituents. Time-of-flight secondary positive ion mass spectra showed peaks at m/z values of 107 and 109, indicating the presence of hydroquinone species at the outermost film surface of the functionalized PPy. The structure of the functionalized monomers was confirmed by C13 and H1 NMR. Cyclic voltammetry (CV) showed the expected electrochemical response of the hydroquinone functionality incorporated into the PPy repeat unit. Functionalized polypyrrole offers potential for pH sensor devices with the electroactive species, conductive support, and mechanical support in an integrated form.
Analysis and Anti-Helicobacter Activity of Sulforaphane and Related Compounds Present in Broccoli (Brassica oleracea L.) Sprouts (2010)

A crude methanol extract prepared from fresh broccoli sprouts was extracted with hexane, chloroform, ethyl acetate, and butanol sequentially. Residual water fraction was obtained from the residual aqueous layer. The greatest inhibition zones (>5 cm) were noted for Helicobacter pylori strain by the chloroform extract, followed by the hexane extract (5.03 cm), the ethyl acetate extract (4.90 cm), the butanol extract (3.10 cm), and the crude methanol extract (2.80 cm), whereas the residual water fraction did not show any inhibition zone. Including sulforaphane, five sulforaphane-related compounds were positively identified in the chloroform extract, of which 5-methylsulfinylpentylnitrile was found in the greatest concentration (475.7 mg/kg of fresh sprouts), followed by sulforaphane (222.6 mg/kg) and 4-methylsulfinylbutylnitrile (63.0 mg/kg). Among 18 sulforaphane and related compounds synthesized (6 amines, 6 isothiocyanates, and 6 nitriles), 2 amines, 6 isothiocyanates, and 1 nitrile exhibited >5 cm inhibitory zones for H. pylori strain. The results indicate that broccoli sprouts can be an excellent food source for medicinal substances.
Biochemical and structural cues of 3D-printed matrix synergistically direct MSC differentiation for functional sweat gland regeneration (2020)

Mesenchymal stem cells (MSCs) encapsulation by three-dimensionally (3D) printed matrices were believed to provide a biomimetic microenvironment to drive differentiation into tissue-specific progeny, which made them a great therapeutic potential for regenerative medicine. Despite this potential, the underlying mechanisms of controlling cell fate in 3D microenvironments remained relatively unexplored. Here, we bioprinted a sweat gland (SG)-like matrix to direct the conversion of MSC into functional SGs and facilitated SGs recovery in mice. By extracellular matrix differential protein expression analysis, we identified that CTHRC1 was a critical biochemical regulator for SG specification. Our findings showed that <i>Hmox1</i> could respond to the 3D structure activation and also be involved in MSC differentiation. Using inhibition and activation assay, CTHRC1 and <i>Hmox1</i> synergistically boosted SG gene expression profile. Together, these findings indicated that biochemical and structural cues served as two critical impacts of 3D-printed matrix on MSC fate decision into the glandular lineage and functional SG recovery.
Three dimensional microfluidics with embedded microball lenses for parallel and high throughput multicolor fluorescence detection (2013)

We report a 3D microfluidic device with 32 detection channels and 64 sheath flow channels and embedded microball lens array for high throughput multicolor fluorescence detection. A throughput of 358 400 cells/s has been accomplished. This device is realized by utilizing solid immersion micro ball lens arrays for high sensitivity and parallel fluorescence detection. High refractive index micro ball lenses (n = 2.1) are embedded underneath PDMS channels close to cell detection zones in channels. This design permits patterning high N.A. micro ball lenses in a compact fashion for parallel fluorescence detection on a small footprint device. This device also utilizes 3D microfluidic fabrication to address fluid routing issues in two-dimensional parallel sheath focusing and allows simultaneous pumping of 32 sample channels and 64 sheath flow channels with only two inlets.
Examination of the Relation between Periodontal Health Status and Cardiovascular Risk Factors: Serum Total and High Density Lipoprotein Cholesterol, C-reactive Protein, and Plasma Fibrinogen (2000)

Using data from the Third National Health and Nutrition Examination Survey (1988-1994), the authors examined the relation between periodontal health and cardiovascular risk factors: serum total and high density lipoprotein cholesterol, C-reactive protein, and plasma fibrinogen. A total of 10,146 participants were included in the analyses of cholesterol and C-reactive protein and 4,461 in the analyses of fibrinogen. Periodontal health indicators included the gingival bleeding index, calculus index, and periodontal disease status (defined by pocket depth and attachment loss). While cholesterol and fibrinogen were analyzed as continuous variables, C-reactive protein was dichotomized into two levels. The results show a significant relation between indicators of poor periodontal status and increased C-reactive protein and fibrinogen. The association between periodontal status and total cholesterol level is much weaker. No consistent association between periodontal status and high density lipoprotein cholesterol was detectable. Similar patterns of association were observed for participants aged 17-54 years and those 55 years and older. In conclusion, this study suggests that total cholesterol, C-reactive protein, and fibrinogen are possible intermediate factors that may link periodontal disease to elevated cardiovascular risk.
Parametric frequency conversion with amplification of a weak spin wave in a ferrite film (1998)

We report on experiments of parametric frequency conversion of a weak signal spin wave by a copropagating strong pump spin wave. An effective spin-wave frequency conversion with amplification occurred when the carrier frequencies of the co-propagating waves were in the spectral region of high negative dispersion in the dipole-exchange spin-wave spectrum of the film. A theoretical explanation of the observed phenomenon is given in terms of a four-wave parametric interaction process.
Abstract LB-B30: First in human, dose escalation trial of the combination of dabrafenib, trametinib, and navitoclax in patients with BRAF mutant solid tumors (2018)

Abstract Combined BRAF and MEK inhibitor therapy is associated with responses in patients (pts) with BRAF mutant solid tumors. Preclinically, the addition of the BH3 mimetic navitoclax improves the efficacy of BRAF inhibitor therapy to BRAF mutant cell lines. CTEP study P9466 (NCT01989585) is a clinical trial designed to test the safety of the combination of dabrafenib, trametinib, and navitoclax (DTN) in patients with BRAF mutant solid tumors. The primary objective of this dose escalation trial was to determine the recommended phase 2 dose (RP2D) of DTN. From March 2014 to August 2017, 25 pts were enrolled, using a 3+3 design, at three dose levels (DL). A one week lead-in of navitoclax 150 mg QD was used to limit thrombocytopenia. Dose limiting toxicities (DLTs) occurred at every dose level and included Grade 3 (Gr) alkaline phosphatase, Gr 3 Rash, Gr 4 thrombocytopenia, and Gr 3 fever. The RP2D was determined to be D 150 mg BID, T 2 mg QD, N 225 mg QD. Severe adverse events (SAEs) occurred in 10 pts. There was one Gr 5 SAE that was possibly related to study drugs (acute kidney injury). Twenty-two of 25 pts were eligible for preliminary efficacy assessment at the time of this submission. Best response, per RECIST1.1, was complete (CR) or partial (PR) response in 6 pts, stable disease (SD) in 7 pts, and disease progression (PD) in 8 pts. Of note, PD was the best response for all 5 pts with melanoma (mel) previously treated with a BRAF inhibitor. In the 6 mel pts who had not received a prior BRAF inhibitor, 5 had a PR or CR (1). Disease control (PR or SD) was seen in most colon cancer (3 of 5) and thyroid cancer (4 of 5) pts. DTN at the RP2D was determined to be safe with preliminary efficacy in pts with BRAF mutant solid tumors. Based on this preliminary data, the randomized phase II portion of this trial of DTN compared to DT in BRAF mutant naïve patients is opening in the ETCTN in the Fall of 2017. Citation Format: Ryan J. Sullivan, Janice Mehnert, Hussain Tawbi, Donald Lawrence, Keith Flaherty, Helen Chen, Naoko Takabe, Michael Davies. First in human, dose escalation trial of the combination of dabrafenib, trametinib, and navitoclax in patients with BRAF mutant solid tumors [abstract]. In: Proceedings of the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; 2017 Oct 26-30; Philadelphia, PA. Philadelphia (PA): AACR; Mol Cancer Ther 2018;17(1 Suppl):Abstract nr LB-B30.
A Methodology to Monitor Airborne PM10 Dust Particles Using a Small Unmanned Aerial Vehicle (2017)

Throughout the process of coal extraction from surface mines, gases and particles are emitted in the form of fugitive emissions by activities such as hauling, blasting and transportation. As these emissions are diffuse in nature, estimations based upon emission factors and dispersion/advection equations need to be measured directly from the atmosphere. This paper expands upon previous research undertaken to develop a relative methodology to monitor PM<sub>10</sub> dust particles produced by mining activities making use of small unmanned aerial vehicles (UAVs). A module sensor using a laser particle counter (OPC-N2 from Alphasense, Great Notley, Essex, UK) was tested. An aerodynamic flow experiment was undertaken to determine the position and length of a sampling probe of the sensing module. Flight tests were conducted in order to demonstrate that the sensor provided data which could be used to calculate the emission rate of a source. Emission rates are a critical variable for further predictive dispersion estimates. First, data collected by the airborne module was verified using a 5.0 m tower in which a TSI DRX 8533 (reference dust monitoring device, TSI, Shoreview, MN, USA) and a duplicate of the module sensor were installed. Second, concentration values collected by the monitoring module attached to the UAV (airborne module) obtaining a percentage error of 1.1%. Finally, emission rates from the source were calculated, with airborne data, obtaining errors as low as 1.2%. These errors are low and indicate that the readings collected with the airborne module are comparable to the TSI DRX and could be used to obtain specific emission factors from fugitive emissions for industrial activities.
Chemical Routes in the Synthesis of Nanomaterials Using the Sol–Gel Process (2007)

In this Account, we discuss the usefulness of the sol-gel process in the synthesis of materials comprising nanoscale architectures. We describe the processing of semiconducting, metallic, ferroelectric, or scintillating nanoparticles in various oxide matrices. We also discuss the synthesis of some nanoporous oxides and organic-inorganic nanohybrids, including core-shell nanostructures.
α-Linolenic acid as a regulator of the metabolism of arachidonic acid: dietary implications of the ratio, n-6:n-3 fatty acids (1985)

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Chiral phosphine ligands modified by crown ethers: an application to palladium-catalyzed asymmetric allylation of .beta.-diketones (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChiral phosphine ligands modified by crown ethers: an application to palladium-catalyzed asymmetric allylation of .beta.-diketonesMasaya Sawamura, Hiroshi Nagata, Hiroaki Sakamoto, and Yoshihiko ItoCite this: J. Am. Chem. Soc. 1992, 114, 7, 2586–2592Publication Date (Print):March 1, 1992Publication History Published online1 May 2002Published inissue 1 March 1992https://pubs.acs.org/doi/10.1021/ja00033a035https://doi.org/10.1021/ja00033a035research-articleACS PublicationsRequest reuse permissionsArticle Views1556Altmetric-Citations170LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts