gebhart/patrepeval huggingface dataset:
The combination of Kaiser window and moving average for the low-pass filtering of the remote ECG signals (2004)

After an analog ECG signal is transferred into digital format, a suitable digital filter can be used to suppress the high-frequency embedded noise. In this paper, we use the equiripple FIR low-pass filter by superimposing of the optimal method, the Butterworth IIR low-pass filter, the 8-point moving-average filter and the FIR filter designed by using a Kaiser window. Furthermore, we combine the 8-point moving-average filter with the FIR filter designed by using a Kaiser window. In addition, we use the mean square error (M. S. E.) to estimate the effect of the digital filters in order to compare the reduction of the embedded high-frequency noise. Hence, we compute the mean square error with respect to the order, N, of these filters and plot the relationship between M. S. E. and N. Finally, we find the relationship between the CPU time and N.
3DPO's strategy for matching three-dimensional objects in range data (2005)

A strategy for recognizing and locating three-dimensional objects in range data is presented. The strategy combines information derived from models of the objects and edges and surfaces detected in the data to efficiently match objects. Given a set of objects to be found, the set of object features are partitioned into subsets having similar intrinsic properties. An ordered tree of features to be considered is set up for each subset. These search trees are designed to maximize the use of the information as it is obtained and minimize the time required to recognize objects. A detailed example of this approach being used to recognize moderately complex castings in a jumble is presented.
Increased expression of galectin-1 in carcinoma-associated stroma predicts poor outcome in prostate carcinoma patients (2001)

Galectin-1, a member of the beta-galactoside-binding galectin family, is a pleiotropic dimeric protein participating in a variety of normal and pathological processes, including cancer progression. Modulation of the interactions with the basement membrane glycoprotein laminin and induction of apoptosis in activated T lymphocytes are well-known functions of this galectin. In this study, the expression of galectin-1 was examined in 148 human primary prostate carcinoma samples. Immunohistochemical staining of paraffin sections of prostate tissues revealed that galectin-1 was not detected in normal, PIN (prostatic intraepithelial neoplasia) or carcinoma cells, but accumulated in the stroma and associated fibroblasts. Galectin-1 expression was significantly increased in the tumour-associated stroma compared with the non-neoplastic gland-associated stroma in 21.3% of the cases (Mantel-Haenszel test, p=0.001; Wilcoxon signed rank test, p<0.0001). Increased galectin-1 expression in the cancer-associated stroma compared to the normal gland-associated stroma (p=0.03) was identified by multivariate analysis as a strong independent predictor of prostate-specific antigen (PSA) recurrence, just after the pathological stage (p<0.0001). The association between accumulation of galectin-1 in the stroma of the malignant tissue and aggressiveness of the tumour adds weight to the body of evidence that identifies a role for galectin-1 in the acquisition of the invasive phenotype. In addition to modulating cancer cell interactions with laminin, galectin-1 accumulated around the cancer cells may act as an immunological shield by inducing activated T-cell apoptosis. This exciting hypothesis warrants further investigation.
Spatial Data Repositories (2005)

This chapter identifies and discusses issues associated with integrating technologies for storing spatial data into business information technology frameworks. A new taxonomy of spatial data storage systems is developed differentiating storage systems by the systems architectures used to enable interaction between client applications and physical spatial data stores, and by the methods used by client applications to query and return spatial data. Five distinct storage models are identified and discussed along with current examples of vendor implementations. Building on this initial discussion, the chapter identifies a variety of issues pertaining to spatial data storage systems affecting three distinct aspects of technology adoption: systems design, systems implementation and management of completed systems. Current issues associated with each of these three aspects are described and illustrated along with a discussion of emerging trends in spatial data storage technologies. As spatial data and the technologies designed to store and manipulate it become more prevalent, understanding potential impacts these technologies may have on other technology decisions within an organization becomes increasingly important. Furthermore, understanding how these technologies can introduce security risks and other vulnerabilities into a computing framework is critical to successful implementation.
Z-path IF-filters for mobile telephones (2003)

IF-filters for channel selection in mobile phone systems must offer narrow bandwidths together with very steep skirts and excellent stopband rejection. Surface acoustic wave (SAW) filters fulfill these requirements. But if conventional transversal design techniques are used chip sizes become too large. The propagation path of the SAW was folded in order to make better use of the total chip length. The use of two slightly inclined reflectors results in a Z-shaped filter which conserves the temperature stability of quartz substrate. At a center frequency of 45 MHz, filters were developed on small chips with good passband characteristics and an insertion loss better than 10 dB. A filter with signal suppression of 20 dB and an ultimate relative stopband rejection of 60 dB is shown.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Secure knowledge management and the semantic web (2005)

Strengthening security within the domain of shared knowledge is a critical issue, and great challenge, to businesses today. A number of different protocols currently available offer an array of benefits and limitations.
Data regularization by Inversion to Common Offset (ICO) (1999)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1999Data regularization by Inversion to Common Offset (ICO)Authors: Nizar CheminguiBiondo BiondiNizar CheminguiStanford University and Biondo BiondiStanford Universityhttps://doi.org/10.1190/1.1820775 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1820775FiguresReferencesRelatedDetailsCited byReconstruction of the near‐offset gap in marine seismic data using seismic interferometric interpolation1 December 2017 | Geophysical Prospecting, Vol. 66, No. S18. Earth Imaging in Depth21 March 2012 SEG Technical Program Expanded Abstracts 1999ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1999 Pages: 2061 publication data© 1999 Copyright © 1999 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished Online: 04 Jan 2005 CITATION INFORMATION Nizar Chemingui and Biondo Biondi, (1999), "Data regularization by Inversion to Common Offset (ICO)," SEG Technical Program Expanded Abstracts : 1398-1401. https://doi.org/10.1190/1.1820775 Plain-Language Summary PDF DownloadLoading ...
Multichannel electrochemical detection with microelectrode array in flowing streams (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMultichannel electrochemical detection with microelectrode array in flowing streamsAtsushi. Aoki, Tomokazu. Matsue, and Isamu. UchidaCite this: Anal. Chem. 1992, 64, 1, 44–49Publication Date (Print):January 1, 1992Publication History Published online1 May 2002Published inissue 1 January 1992https://pubs.acs.org/doi/10.1021/ac00025a009https://doi.org/10.1021/ac00025a009research-articleACS PublicationsRequest reuse permissionsArticle Views230Altmetric-Citations58LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effect of butyrylcholinesterase genotype on the response to rivastigmine or donepezil in younger patients with Alzheimer's disease (2006)

A randomized double-blind trial evaluated the efficacy and tolerability of rivastigmine, an inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), and donepezil, an AChE-selective inhibitor, in patients with Alzheimer's disease over a 2-year period. A retrospective analysis showed differential responses to cholinesterase inhibitors (ChE-Is) in patients younger than 75 years. This analysis investigated the effect of BuChE genotype on response to ChE-I therapy in these patients. In a retrospective analysis, patients younger than 75 who had consented to pharmacogenetic analysis were divided into groups according to BuChE genotype. Efficacy measures were the Severe Impairment Battery (SIB), Neuropsychiatric Inventory (NPI), Global Deterioration Scale (GDS), Mini-Mental State Examination (MMSE) and the Alzheimer's Disease Cooperative Study-Activities of Daily Living Scale (ADCS-ADL). Changes on efficacy parameters were calculated for rivastigmine-treated and donepezil-treated patients in both groups. Of 114 (34.1%) patients younger than 75 who were successfully assessed for BuChE genotype, 76 (66.7%) were homozygous for wild-type BuChE, and 38 (33.3%) carried at least one BuChE K-variant allele. Wild-type BuChE carriers showed significantly greater responses to rivastigmine than to donepezil on the SIB, ADCS-ADL, GDS and NPI. No significant between-treatment differences in efficacy were observed in BuChE K-variant carriers, although adverse events were more frequent in rivastigmine-treated patients. In this retrospective analysis, Alzheimer's disease patients younger than 75 with wild-type BuChE exhibited differential efficacy to rivastigmine, while BuChE K-variant carriers experienced similar long-term treatment effects with both agents. These differences may reflect rivastigmine's ability to inhibit BuChE and AChE.
Effect of different levels of bacterial probiotic on broilers performance (2003)

The microbial populations in the gastrointestinal tracts of poultry play a key role in normal digestive processes and in maintaining animal health. Disease- and stress-induced changes in the physicochemical environment in the gastrointestinal tract, or simple changes in feed management practices can significantly influence the microbial populations and their effects on animal performance and health. In the last five decades, increased knowledge of the factors that influence the activities of microorganisms in the alimentary tract has helped to define the critical role of these symbiotic organisms. Probiotics, competitive exclusion and direct-fed microbial feed supplements can be used as a strategic tool for managing these microbial populations. The aim of this trial was study of effect of different levels of bacterial probiotic on broilers performance and some of blood factors.
ChemInform Abstract: The Synthesis of Two Novel Fused Thienopyridopyridazines. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Substrate Specificity of Atrazine Chlorohydrolase and Atrazine-Catabolizing Bacteria (2000)

Bacterial atrazine catabolism is initiated by the enzyme atrazine chlorohydrolase (AtzA) in Pseudomonas sp. strain ADP. Other triazine herbicides are metabolized by bacteria, but the enzymological basis of this is unclear. Here we begin to address this by investigating the catalytic activity of AtzA by using substrate analogs. Purified AtzA from Pseudomonas sp. strain ADP catalyzed the hydrolysis of an atrazine analog that was substituted at the chlorine substituent by fluorine. AtzA did not catalyze the hydrolysis of atrazine analogs containing the pseudohalide azido, methoxy, and cyano groups or thiomethyl and amino groups. Atrazine analogs with a chlorine substituent at carbon 2 and N-alkyl groups, ranging in size from methyl to t-butyl, all underwent dechlorination by AtzA. AtzA catalyzed hydrolytic dechlorination when one nitrogen substituent was alkylated and the other was a free amino group. However, when both amino groups were unalkylated, no reaction occurred. Cell extracts were prepared from five strains capable of atrazine dechlorination and known to contain atzA or closely homologous gene sequences: Pseudomonas sp. strain ADP, Rhizobium strain PATR, Alcaligenes strain SG1, Agrobacterium radiobacter J14a, and Ralstonia picketti D. All showed identical substrate specificity to purified AtzA from Pseudomonas sp. strain ADP. Cell extracts from Clavibacter michiganensis ATZ1, which also contains a gene homologous to atzA, were able to transform atrazine analogs containing pseudohalide and thiomethyl groups, in addition to the substrates used by AtzA from Pseudomonas sp. strain ADP. This suggests that either (i) another enzyme(s) is present which confers the broader substrate range or (ii) the AtzA itself has a broader substrate range.
Recombinant measles virus incorporating heterologous viral membrane proteins for use as vaccines (2016)

Recombinant measles virus (rMV) vectors expressing heterologous viral membrane protein antigens are potentially useful as vaccines. Genes encoding the mumps virus haemagglutinin-neuraminidase (MuV-HN), the influenza virus haemagglutinin (Flu-HA) or the respiratory syncytial virus fusion (RSV-F) proteins were inserted into the genome of a live attenuated vaccine strain of measles virus. Additionally, in this case rMV with the MuV-HN or the influenza HA inserts, chimeric constructs were created that harboured the measles virus native haemagglutinin or fusion protein cytoplasmic domains. In all three cases, sucrose-gradient purified preparations of rMV were found to have incorporated the heterologous viral membrane protein on the viral membrane. The possible utility of rMV expressing RSV-F (rMV.RSV-F) as a vaccine was tested in a cotton rat challenge model. Vaccination with rMV.RSV-F efficiently induced neutralizing antibodies against RSV and protected animals from infection with RSV in the lungs.
Ion beam patterning of spin-on metalorganic precursors and formation of high <i>T</i> <i>c</i> superconductors (1988)

A new technique using ion beams to produce patterned thin films of the high-temperature perovskite superconductor YBa2Cu3O7−x from spin-on metalorganic precursors is described. Spin-coated precursor films are irradiated through a stencil mask with 2.5 MeV He+ ions, developed in solvent to remove unexposed material, and the remaining patterns are pyrolyzed. Black films of YBa2Cu3O7−x with pattern dimensions on the millimeter scale exhibit orientation with the c axis perpendicular to the film after heat treatments of 990 °C for 3 min. The conductivity of a highly oriented, ∼0.4-μm-thick patterned film is characterized by onset of the superconducting transition at 84 K and zero resistivity at 68 K, similar to those of an unirradiated film given the same thermal treatment. Studies on the nature of the ion beam exposed material are discussed.
An Improved Pre-processing Approach for Photoplethysmographic Signal (2005)

Heart rate variability and motion artifact are two major obstacles to the Photoplethysmographic (PPG) signal analysis, which is a very promising tool to derive useful information about the hemodynamics as well as autonomic nerve system. This paper suggests employing a truncation/extrapolation method on the PPG signal or its first order derivative to overcome the heart rate variability problem while extract a refined mean PPG pulse waveform. Meanwhile, the cross-correlation detection method is employed to remove the motion artifacts. Test results indicate that the proposed approach can effectively enhance the signal to noise ratio of PPG waveform and therefore verify the effectiveness of the proposed preprocessing scheme.
Factors affecting monoclonal antibody production in culture. (1987)

Factors that affect production of monoclonal antibodies (McAb) by a murine cell line were investigated. The goal was to estimate the efficiency of large scale production in stirred reactors. It was found that in batch cultures most McAb was produced after the log growth phase; final yield was 100-200 micrograms/ml. Yields of McAb were increased to 290 micrograms/ml by feeding cells glucose and glutamine. Lactic acid, which was produced in culture as a result of glucose metabolism, had no toxic effect on cells, while another waste product, ammonium ion, was probably accumulated at toxic levels during late stages of cell growth. The hybridoma cell line was propagated in four different systems: fed-batch, semi-continuous, two stage and perfusion. These systems were compared to batch cultures for their effect on cell viability and antibody production. Daily addition of fresh medium (fed-batch propagation) increased antibody productivity from 15 (batch culture) to 27 mg/l of culture/day. In the semi-continuous culture productivity was raised to 34 mg/l/day. Further increase in productivity to a level of 62 mg/l/day was achieved by applying a second batch stage to the semi-continuous culture. A perfusion culturing method was the most effective for production of McAb. Average concentrations of 2.2 X 10(7) live cells/ml and 390 micrograms of antibody/ml corresponding to productivity of 660 mg/l/day were achieved. Serum concentration in the medium was reduced to 0.125% resulting in a specific activity of 0.4 mg of McAb per mg of protein in the cell-free culture broth.
THE HOST RANGE AND PLAQUE MORPHOLOGY OF RABBITPOX VIRUS (RP<i>u</i>+) AND ITS <i>u</i> MUTANTS ON CHICK FIBROBLAST, PK‐2a, AND L929 CELLS (1965)

Summary Rabbitpox virus (RP u +), 18 white pock ( u ) mutants derived from it and several strains of vaccinia virus were examined in respect to their cytopathology in chick embryo fibroblast cultures, and several continuous lines of mammalian cells; PK‐2a (pig kidney), L929 (mouse fibroblast), FAF (Chinese hamster fibroblast), AT (Chinese hamster, epithelial), KB (human epithelial), FL (human amnion) and Chang liver (human epithelial). The plaquing characteristics of the viruses, and the capacity to multiply exhibited by those which did not produce plaques, were investigated in chick fibroblast, PK‐2a, and L929 cells. Cytopathic changes were characterized by early toxic effects, cellular fusion, and progressive destruction of monolayers, the pattern of changes being a function of specific virus‐cell combinations. With input inocula of 1‐5 PFU per cell, most of the virus strains and mutants produced toxic changes in most of the epithelial type cells (PK‐2a, FL, Chang liver) but not in the fibroblastic cells, and to a very slight degree in KB cells. Three mutants which failed to multiply in PK‐2a cells nevertheless produced moderate toxic changes in them. Pronounced fusion of cells was produced in the epithelial type cells, but not in fibroblastic cells, by most of the viruses which multiplied in them, but not by mutants which failed to multiply. All the mutants produced plaques on chick embryo fibroblasts, and these could be distinguished as turbid or clear, and differed in size and in cultural requirements for maximal plating efficiency. A standard plaque assay method is described which gives good plaques with the majority of mutants. Conditions for optimal plaque assays on PK‐2a and L929 cells are also described, and several distinctive plaque types were recognized. Some mutants failed to produce plaques on PK‐2a or L929 cells, and in all cases except one this was shown to be due to their failure to multiply in the cells concerned.
13-cis-Retinoic Acid and Interferon   -2a: Effective Combination. Therapy for Advanced Squamous Cell Carcinoma of the Skin (1992)

These results indicate that combined systemic therapy with 13-cRA and IFN alpha-2a is highly effective in patients with advanced squamous cell carcinoma of the skin.
Acrylic polyester resins containing perfluoropolyethers structures: Synthesis, characterization, and photopolymerization (2000)

Poly(ε-caprolactone-b-perfluoropolyether-b-εcaprolactone) (PCL–PFPE–PCL) block copolymers having different PCL block lengths and end-capped with methacrylate groups were prepared and characterized. Spectroscopic analyses confirmed the expected molecular structure of the products. After UV curing, the films revealed the presence of two amorphous phases, corresponding to fluorinated and hydrogenated moieties, respectively. The material containing long PCL blocks showed also a crystalline phase. Surface properties of the UV-cured films were evaluated: The surfaces have a very high hydrophobic character in spite of the presence of many polar OH groups present in the polymeric network and a high hysteresis in wetting. An enrichment of fluorine at the air-side surface was shown by contact-angle measurements, except when long PCL sequences are present. The θadv angles decreased by increasing the content of PCL, that is, by decreasing the content of fluorine. © 2000 John Wiley & Sons, Inc. J Appl Polym Sci 75: 651–659, 2000
Measurement of Forbidden Energy Gap of Semiconductors by Diffuse Reflectance Technique (1970)

Abstract Diffuse reflectance technique for the measurement of forbidden energy gap, E g , is discussed. The energy coordinate of the point at which the linear increase in the Kubelka‐Munk function starts gives the E g ‐value. The E g ‐values of fifteen semiconductors are reported. These E g ‐values are found to be in good agreement with those measured by other methods.
Distributed key generation protocol with hierarchical threshold access structure (2015)

A distributed key generation (DKG) protocol is a central component in distributed cryptosystems. It allows a group of participants to jointly generate a pair of keys (private key and public key) without assuming any trusted participant. The public key is output in clear but only authorised subgroups of participants are able to reconstruct or use the private key. Existing literature on DKG protocols assumes equal authority for participants. In this study, the authors consider the problem of DKG in groups with hierarchical structure where the authorised subsets can be defined by a hierarchical threshold access structure. They first propose a verifiable hierarchical threshold secret sharing protocol. On the basis of this construction, they then propose a new DKG protocol with hierarchical threshold access structure for discrete‐logarithm‐based cryptosystems. It is shown that the proposed protocols satisfy all the security requirements.