gebhart/patrepeval huggingface dataset:
Near-infrared surface-enhanced-Raman-scattering (SERS) mediated identification of single optically trapped, bacterial spores (2003)

A novel methodology has been developed for the investigation of bacterial spores. Specifically, this method has been used to probe the spore coat composition of several Bacillus species. This technique may be useful in many applications; most notably, development of novel detection schemes toward potentially harmful biological agents. This method would also be useful as an ancillary environmental monitoring system where sterility is of importance (i.e., food preparation areas as well as invasive and minimally invasive medical applications). This unique detection scheme is based on the near-infrared (NIR) Surface-Enhanced-Raman-Scattering (SERS) from single, optically trapped, bacterial spores. The SERS spectra of several bacterial spores in aqueous media have been measured using SERS substrates based on 60-nm diameter gold colloids bound to 3-Aminopropyltriethoxysilane derivatized glass. The light from a 785-nm laser diode was used to capture/manipulate as well as simultaneously excite the SERS of an individual bacterial spore. The collected SERS spectra were examined for uniqueness and the applicability of this technique for the species identification of bacterial spores.
Creative thinking abilities of cleft palate children. (1966)

A great amount of research activity is being devoted to studying creative thought from various dimensions. Generally, experimenters have limited their work to studying the creative process, person, product, or environmental factors related to, and perhaps influencing, creativity. The impetus for this line of investigation has come from Guilford's report on the Structure of Intellect (4) wherein he identified, theoretically, 120 possible factors of intellect. Immediately, psychologists began developing tests to assess ability in each of these areas. Additionally, attention has been directed toward relating constellations of these factors to more global concepts. The contemporary research in creative thought has evolved from and is primarily based on certain dimensions of the Structure of Intellect model, notably the factors related to divergent thinking. These factors are evaluated by tests which allow an individual to respond to a stimulus in as many ways as he can. Basically, the instruments evaluate verbal and nonverbal fluency, flexibility, originality, and the elaboration of ideas (3). Interestingly enough, scores from the creativity tests evalu— ating these factors of intellect do not correlate significantly with scores from standardized intelligence tests such as the Stanford-Binet Intelligence Test or the Wechsler Intelligence Scale for Children (14). This indicates that the tests are measuring dimensions of intelligence other than those evaluated by standard intelligence tests. Consideration has also been given to describing characteristics of the creative person, as well as those aspects of the environment which facili— tate or inhibit creativity. In summary, the research indicates that the creative person tends to be unusually perceptive, able to evaluate himself from an internal frame of reference, skilled in relieving anxieties in ways other than through repression or suppression, exhibit humor frequently, and show a tendency towards self-autonomy, which seems to be associ-Dr. Smith,
Uplink Signaling and Receive Beamforming for Dual-Function Radar Communications (2018)

Current techniques for dual-function radar-communications (DFRC) have been focused on downlink communication and information embedding into the emission of the radar system. In this paper, we consider the problem of half-duplex uplink communications in dual-function multiple-input multiple-output (MIMO) radar communication systems. The DFRC system consists of a dual-function platform which functions as a MIMO radar during transmit mode and simultaneously receives and processes signals reflected from targets and uplink communication signals transmitted by a communication user. We propose a method for uplink signaling via forming a number of uplink beams carrying the same number of data symbols. Moreover, we employ non-adaptive and adaptive beamforming techniques at the radar receiver to separate the received communication signal from the target return even if they arrive from the same spatial angle. Cross-interference between the received communication and the reflected radar signals is mitigated using adaptive beamforming. We assess the effectiveness of the proposed uplink communication technique by numerical results.
Evaluating web-sources: Internet literacy and L2 academic writing (2005)

Journal Article Evaluating web-sources: Internet literacy and L2 academic writing Get access Paul Stapleton Paul Stapleton Paul Stapleton is a professor at Hokkaido University in Japan. His current interest is in academic writing. Email: paulstapleton@gmail.com Search for other works by this author on: Oxford Academic Google Scholar ELT Journal, Volume 59, Issue 2, April 2005, Pages 135–143, https://doi.org/10.1093/eltj/cci027 Published: 01 April 2005
Half mode substrate integrated waveguide slot antenna (2009)

In this paper, we demonstrate a half mode Substrate Integrated Waveguide ldquoSIWrdquo slot antenna. According to the test results of fabrication, the size of original antenna is reduced to half, and still works at 5 GHz with proper bandwidth.
An integrated three‐component approach to fracture detection (1986)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1986An integrated three‐component approach to fracture detectionAuthors: M. A. MartinT. L. DavisT. J. O'RourkeM. A. MartinColorado School of Mines, T. L. DavisColorado School of Mines, and T. J. O'RourkeColorado School of Mineshttps://doi.org/10.1190/1.1893146 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1893146FiguresReferencesRelatedDetailsCited ByTwelve years of vertical birefringence in nine‐component VSP dataDonald F. Winterstein, Gopa S. De, and Mark A. Meadows7 February 2012 | GEOPHYSICS, Vol. 66, No. 2Birefringence study on 3‐C/2‐D: Barinas Basin (Venezuela)Maria S. Donati and R. James Brown10 February 2005Ray series modeling of seismic wave travel times and amplitudes in three-dimensional heterogeneous anisotropic crystalline rock: Borehole vertical seismic profiling seismograms from the Mojave Desert, California1 January 1990 | Journal of Geophysical Research, Vol. 95, No. B7An integrated study of seismic anisotropy and the natural fracture system at the Conoco Borehole Test Facility, Kay County, Oklahoma1 January 1990 | Journal of Geophysical Research, Vol. 95, No. B7 SEG Technical Program Expanded Abstracts 1986ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1986 Pages: 715 publication data© 1986 Copyright © 1986 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 07 Mar 2005 CITATION INFORMATION M. A. Martin, T. L. Davis, and T. J. O'Rourke, (1986), "An integrated three‐component approach to fracture detection," SEG Technical Program Expanded Abstracts : 235-236. https://doi.org/10.1190/1.1893146 Plain-Language Summary PDF DownloadLoading ...
Simple Procedure for Large-Scale Assays for Chick Interferon (1977)

Details are given of a simple and rapid method for the determination of chick interferon concentrations, using the Cooke microtiter system. The reliability of the result of this assay was examined by multiple determinations and by comparison with the results of another known assay procedure. A comparison of the relative time and cost of performing the two assays is also given.
Isolation and Identification of  <i>Bacillus</i>  spp. and Related Genera from Different Starchy Foods (2010)

Foodborne illness produce by B. cereus have been associated with a wide variety of food. In addition, some other Bacillus species have been related to foodborne disease in humans. Information about the virulence mechanisms of other Bacillus spp. is scanty and their risk is underestimated. Identifying the group of food and the food processes in which Bacillus cereus or other Bacillus spp. would be hazardous for human health is vital for the prevention of foodborne outbreak. In this study, we determined the incidence of Bacillus spp. and related genera in some food items of agriculture origin from Argentina. This research is relevant to identify the presence of potentially pathogen Bacillus species and related genera in this type of food.
Higher-order attribute grammars and editing environments (1990)

Article Free Access Share on Higher-order attribute grammars and editing environments Authors: Tim Teitelbaum Department of Computer Science, Cornell University, Ithaca, NY Department of Computer Science, Cornell University, Ithaca, NYView Profile , Richard Chapman Department of Computer Science, Cornell University, Ithaca, NY Department of Computer Science, Cornell University, Ithaca, NYView Profile Authors Info & Claims PLDI '90: Proceedings of the ACM SIGPLAN 1990 conference on Programming language design and implementationJune 1990 Pages 197–208https://doi.org/10.1145/93542.93567Published:01 June 1990Publication History 17citation435DownloadsMetricsTotal Citations17Total Downloads435Last 12 Months20Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Growth - Promoting Effects of Vegetable Extracts on Selected Human Lactic Acid Bacteria (2001)

Ethanol extracts from 36 vegetable samples were assayed for their growth-promoting effects on Bifidobacterium bifidum, B. longum, and Lactobacillus casei. The growth-promoting effects varied according to bacterial strain and vegetable species. In modified Gyorgy broth, extracts of Lactuca sativa, Lycopersicon esculentum and L. esculentum var. cerasiforme exhibited strong growth-promoting responses toward B. longum, and significant and strong growth-promoting response toward B. bifidum was observed in extracts of Actinidia arguta, Allium cepa, A. sativum, Brassica campestris subsp. napus var. pekinensis, Capsicum frutescens, Daucus carota var. sativa, L. sativa, L. esculentum and L. esculentum var. cerasiforme, Nelumbo nucifera, Cucurbita moschata, Lactuca var. sapitata, and Rubus coreanus. For L. casei, extracts of A. tuberosum, Cichorium intybus, Cucurbita moschata, Ipomoea batatas, L. sativa var. capitata, L. esculentum, P. brachycarpa, Raphanus sativus, R. coreanus, and S. melongena strongly enhanced the growth of this bacteria. In modified Gyorgy broth, the promoting effect was most pronounced with B. bifidum and L. casei among lactic acid bacteria used. In MRS broth, A. arguta, A. cepa, A. sativum, B. campestris sllbsp. naplls var. pekine1lsis, C. frutescens, and D. carota var. sativa, L. sativa var. capitata, and R. coreanlls strongly enhanced the growth of B. bifidllm. Growth of B. longum was strongly affected by the addition of extracts from L. sativa var. capitata. For L. casei, moderate growth-promoting responses were observed in 9 vegetable extracts. The promoting effect in MRS broth was most pronounced with B. bifidllm among lactic acid bacteria used.
Electrochemical treatment of localized tumors with direct current (2002)

To develop cancer electrochemical treatment (ECT) in the United States, we have conducted basic studies and started a Phase I clinical trial. Our in vivo preliminary results indicate that ECT is effective on RIF-I mouse tumor and rat fibrosarcomas. In the in vitro study ECT clearly demonstrated dose-dependent human oral carcinoma KB cell growth inhibition by colony-forming assay. We have started an animal study to resolve the ECT methodological problems for rat breast cancer. Meanwhile, we began a clinical trial treating patients with recurrent superficial measurable malignant tumors. Our goal is to make ECT a useful alternative method for treating localized tumors.
Two‐year follow‐up of patients with septic shock presenting with low <scp>HDL</scp>: the effect upon acute kidney injury, death and estimated glomerular filtration rate (2017)

Low HDL levels during sepsis are associated with increased risk of sepsis-associated AKI, and/or subsequent decreased eGFR. These results suggest that HDL may be involved and/or may be a marker of kidney injury during and after sepsis.
The bee venom peptide tertiapin underlines the role of <i>I</i><sub>KACh</sub> in acetylcholine‐induced atrioventricular blocks (2000)

Acetylcholine (ACh) is an important neuromodulator of cardiac function that is released upon stimulation of the vagus nerve. Despite numerous reports on activation of I(KACh) by acetylcholine in cardiomyocytes, it has yet to be demonstrated what role this channel plays in cardiac conduction. We studied the effect of tertiapin, a bee venom peptide blocking I(KACh), to evaluate the role of I(KACh) in Langendorff preparations challenged with ACh. ACh (0.5 microM) reproducibly and reversibly induced complete atrioventricular (AV) blocks in retroperfused guinea-pig isolated hearts (n=12). Tertiapin (10 to 300 nM) dose-dependently and reversibly prevented the AV conduction decrements and the complete blocks in unpaced hearts (n=8, P<0.01). Tertiapin dose-dependently blunted the ACh-induced negative chronotropic response from an ACh-induced decrease in heart rate of 39+/-16% in control conditions to 3+/-3% after 300 nM tertiapin (P=0.01). These effects were not accompanied by any significant change in QT intervals. Tertiapin blocked I(KACh) with an IC(50) of 30+/-4 nM with no significant effect on the major currents classically associated with cardiac repolarisation process (I(Kr), I(Ks), I(to1), I:(sus), I(K1) or I(KATP)) or AV conduction (I(Na) and I(Ca(L))). In summary, tertiapin prevents dose-dependently ACh-induced AV blocks in mammalian hearts by inhibiting I(KACh).
Biosynthesis of phosphoinositol-containing sphingolipids from phosphatidylinositol by a membrane preparation from Saccharomyces cerevisiae (1980)

Incubation of membranes prepared from Saccharomyces cerevisiae with [32P]phosphatidyl[3H]inositol resulted in the transfer of both labels to two products which were characterized as two species of inositolphosphoceramide, differing in the ceramide portion of the molecule. The products were characterized on the basis of stability in mild alkali, mobility on silica gel-impregnated paper, chromatography on silicic acid columns, and release of inositol phosphate upon base hydrolysis. The reaction did not require the addition of metals, nor was it inhibited by ethylenediaminetetraacetic acid. The detergents Triton X-100 and Tween 20 provided little, if any, stimulation. At relatively high concentrations of phosphatidylinositol (1 to 4 mM), the in vitro rate was about 20% of the in vivo rate. Although ceramide was a logical substrate, the reaction could not be greatly stimulated by the addition of ceramides containing mono- and dihydroxy fatty acids. In addition, incubation of yeast membranes with [32P]phosphatidylinositol gave rise to a product that was chromatographically indistinguishable from the major yeast phosphosphingolipid, mannose-(inositol-P)2 ceramide.
Synthesis of Mixed Alkylphosphites and Alkylphosphates (2003)

Some mixed phosphites having two different alkyl chain were obtained as forerunners for mixed phosphates Mixed dialkyl phosphates were obtained in good yields (40-80%) by phase transfer catalysis in liquid-liquid sistem, starting from different dialkyl phosphites and aliphatic alcohols. The reaction conditions were optimized in order to obtain good yields in phosphites and phosphates respectively. Compounds were analyzed by IR, P 31 -NMR.
Diagnosing visceral leishmaniasis with the recombinant K39 strip test: experience from the Sudan (2001)

We compared a strip test employing recombinant K39 (rK39) antigen and protein A/colloidal gold as read-out agents with the rK39 ELISA for IgM and IgG antibodies and the direct agglutination test (DAT) using 55 sera from patients with parasitologically confirmed visceral leishmaniasis (VL). The rK39 strip test was positive in 37/55 (67%), the DAT in 50/55 (91%) at > or = 1 : 1600 cut-off value and in 47/55 (85%) at > or = 1 : 6400 cut-off value. The rK39-ELISA gave positive IgG results for all sera; those who had a positive strip test had significantly higher IgG levels than those with a negative strip test (31.1 (SD=3.6) and 17.7 U/ml (SD=9.8), respectively, P < 0.0001). A total of 31/55 (56%) sera showed a positive IgM result; of these 27 (49%) had a positive strip test. We tested 115 apparently cured VL patients with the strip test during follow-up; 68 were also tested with DAT. In the strip test, 25-43% of patients had a positive result at time points 3, 6, 9 and 12 months after treatment; for DAT (cut-off > or = 1 : 1600) these results were 67-83%. In neither test did a significant decrease in positivity rates occur over time (P=0.37 for the strip test, P=0.17 for the DAT). No correlation (P=0.33) was found between a positive strip test and a positive DAT result (cut-off > or = 1: 1600), indicating that the strip test and DAT are complementary rather than interchangeable. Of 61 endemic controls two (3%) had a positive strip test result; both had a positive leishmanin skin test. The rK39 strip test has the ideal format for use in the field, but its sensitivity is limited; like DAT, but to a lesser extent, it remains positive after treatment.
Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure (2007)

Angiotensin-converting enzyme (ACE) inhibitors represent the front-line pharmacological treatment of heart failure, which is characterized by left ventricular (LV) dilatation and inappropriate hypertrophy. The mechanism of action of ACE inhibitors is still unclear, but evidence suggests that they may act by influencing matrix metalloproteinase (MMP) activity. This study sought to determine whether ACE inhibitors can directly regulate MMP activity and whether this results in positive structural and functional adaptations to the heart. To this end, MMP-2 activity in LV tissue extracted from rats with an aortocaval (AV) fistula was assessed by in vitro incubation as well as in vivo treatment with captopril, lisinopril, or quinapril. Furthermore, LV size and function were determined in untreated AV fistula rats, AV fistula rats treated with lisinopril (3, 5, and 8 wk), and age-matched sham-operated controls. In vitro incubation with captopril, lisinopril, or quinapril significantly reduced MMP-2 activity, as did in vivo treatment. This occurred without a reduction in the available pool of MMP-2 protein. Long-term in vivo administration of lisinopril also prevented LV dilatation, attenuated myocardial hypertrophy, and prevented changes in myocardial compliance and contractility. The results herein demonstrate that ACE inhibitors prevent MMP-2 activity and, in so doing, represent a mechanism responsible for preventing the negative structural and functional changes that occur in the rat AV fistula model of heart failure.
<i>In situ</i>use of suicide genes for therapy of brain tumours (1999)

Suicide gene therapy represents a new therapeutic approach to the treatment of patients with otherwise incurable malignant brain tumours. This strategy involves the introduction of a gene that renders the tumour cell susceptible to an otherwise nontoxic prodrug. The most often used genetic prodrug activation system is the herpes simplex virus thymidine kinase/ganciclovir (HSV-tk/GCV) paradigm. An important aspect of this system is the 'bystander effect', the extension of cytotoxic effects to untransduced cells. For gene delivery, retroviral, adenoviral vectors and HSV-1 mutants have been used. Clinical studies have revealed that the HSV-tk/GCV approach is safe, but also that responses are observed only in very small brain tumours, indicating insufficient vector distribution and very low transduction efficiency with replication-deficient vector systems. To improve treatment efficacy, the use of replication-competent oncolytic vectors in combination with new or improved prodrug-suicide gene systems as a part of a multimodal approach is warranted. In the context of replication-competent vectors, suicide genes might also be used as fail-safe genes in the case of runaway infection.
Analyzing spike trains with circular statistics (2009)

In neuroscience, specifically electrophysiology, it is common to replace a measured sequence of action potentials or spike trains with delta functions prior to analysis. We apply a method called circular statistics to a time series of delta functions and show that the method is equivalent to the power spectrum. This technique allows us to easily visualize the idea of the power spectrum of spike trains and easily reveals oscillatory and stochastic behavior. We provide several illustrations of the method and an example suitable for students, and suggest that the method might be useful for courses in introductory biophysics and neuroscience.
Efficient Inventory Optimization of Multi Product, Multiple Suppliers with Lead Time using PSO (2010)

With information revolution, increased globalization and competition, supply chain has become longer and more complicated than ever before. These developments bring supply chain management to the forefront of the managements attention. Inventories are very important in a supply chain. The total investment in inventories is enormous, and the management of inventory is crucial to avoid shortages or delivery delays for the customers and serious drain on a companys financial resources. The supply chain cost increases because of the influence of lead times for supplying the stocks as well as the raw materials. Practically, the lead times will not be same through out all the periods. Maintaining abundant stocks in order to avoid the impact of high lead time increases the holding cost. Similarly, maintaining fewer stocks because of ballpark lead time may lead to shortage of stocks. This also happens in the case of lead time involved in supplying raw materials. A better optimization methodology that utilizes the Particle Swarm Optimization algorithm, one of the best optimization algorithms, is proposed to overcome the impasse in maintaining the optimal stock levels in each member of the supply chain. Taking into account the stock levels thus obtained from the proposed methodology, an appropriate stock levels to be maintained in the approaching periods that will minimize the supply chain inventory cost can be arrived at.