gebhart/patrepeval huggingface dataset:
Grafting Imparts Glyphosate Resistance in Soybean (2013)

Grafting is a widely-adopted cultural method to incorporate desired traits of rootstock with those of the scion and has been used successfully to address many biotic and abiotic stresses, including drought/waterlogging, insects, and diseases. However, it is not known if a herbicide resistance trait can be transferred across a graft union. Using Roundup Ready® (RR; glyphosate-resistant) soybean grafted with conventional (CN; nontransgenic and glyphosate-sensitive) soybean, we show that grafting is capable of transferring glyphosate resistance from RR rootstocks to CN scions. Grafts of CN/CN (scion/rootstock), CN/RR, RR/CN, and RR/RR were treated with potassium salt of glyphosate at 0.28, 0.84 and 1.68 kg ae ha −1 . The CN/RR plants survived glyphosate treatment at 0.84 and 1.68 kg ha −1 while CN/CN plants were killed, indicating that glyphosate resistance is systemically mobile across the graft union. Intraspecies transfer of glyphosate resistance was unidirectional from root to shoot, since RR/CN plants were killed by glyphosate. The glyphosate resistance trait is conferred by CP4 5-enolpyruvylshikimate-3-phosphate synthase (CP4-EPSPS); therefore, we further examined whether CP4-EPSPS played a role in the phenomenon. CP4-EPSPS was detected in the CN scion of CN/RR plants by enzyme-linked immunosorbent assay (ELISA) but only 0.001% of that detected in RR leaf. This concentration is unlikely to have contributed significantly to the glyphosate resistance observed in CN/RR plants. Amino acid systemic trafficking and/or tissue specific glyphosate resistance are more likely the reasons for this phenomenon. These results show that grafting a transgenic herbicide-resistant rootstock to a nonresistant scion can confer resistance to the entire plant.
Polymorphic Blocks: Unifying High-level Specification and Low-level Control for Circuit Board Design (2020)

Mainstream board-level circuit design tools work at the lowest level of design --- schematics and individual components. While novel tools experiment with higher levels of design, abstraction often comes at the expense of the fine-grained control afforded by low-level tools. In this work, we propose a hardware description language (HDL) approach that supports users at multiple levels of abstraction from broad system architecture to subcircuits and component selection. We extend the familiar hierarchical block diagram with polymorphism to include abstract-typed blocks (e.g., generic resistor supertype) and electronics modeling (i.e., currents and voltages). Such an approach brings the advantages of reusability and encapsulation from object-oriented programming, while addressing the unique needs of electronics designers such as physical correctness verification. We discuss the system design, including fundamental abstractions, the block diagram construction HDL, and user interfaces to inspect and fine-tune the design; demonstrate example designs built with our system; and present feedback from intermediate-level engineers who have worked with our system.
<b>Directive Effects in the Attack of Phenyl Radicals on Carbon-Hydrogen Bonds</b> (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDirective Effects in the Attack of Phenyl Radicals on Carbon-Hydrogen BondsRobert F. Bridger and Glen A. RussellCite this: J. Am. Chem. Soc. 1963, 85, 23, 3754–3765Publication Date (Print):December 1, 1963Publication History Published online1 May 2002Published inissue 1 December 1963https://pubs.acs.org/doi/10.1021/ja00906a009https://doi.org/10.1021/ja00906a009research-articleACS PublicationsRequest reuse permissionsArticle Views491Altmetric-Citations149LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Accumulation of arsenic species in serum of patients with chronic renal disease (1996)

Speciation of arsenic was determined in serum of 19 non-hemodialysis (non-HD) and 18 HD patients. The respective mean values of serum creatinine in these groups were 410 +/- 250 and 914 +/- 173 mumol/L (reference range for healthy subjects: females 50-80; males 57-93 mumol/L). The mean total arsenic concentrations were 5.12 +/-5.58 and 6.47 +/- 4.28 micrograms/L, respectively (reference value: 0.958 +/-1.52 micrograms/L). Dimethylarsinic acid (DMA) and arsenobetaine (AsB) were the major As species in serum of the non-HD and HD patients, with mean values of 0.82 +/- 1.05 and 1.93 +/- 1.51 micrograms/L for DMA and 3.55 +/- 4.58 and 3.47 +/- 2.89 micrograms/L for AsB, respectively. Serum concentrations of inorganic As and monomethylarsonic acid in both groups were below the detection limits for these compounds. Measurement of As concentration before vs after 4 h of HD treatment indicated that 68% of total As in serum was removed, as was 16% of the total As in packed cells. The efficiency of DMA and AsB removal during dialysis corresponded to that of total As.
Determining the Angular Motion of a Rigid Body Using Linear Accelerometers Without Integration (2007)

It is shown that the angular acceleration and velocity of a rigid body can be determined from translational material acceleration measurements made by an observer on the body. An important contribution is the fact is that this can be done without integration. Therefore, ideally, the solutions are obtained at any instant simultaneously. Also shown is that whereas the angular acceleration solution is unique, there always exists two solutions for the angular velocity that only differ in sign, which cannot be resolved any further. The necessary and sufficient number of points is proven to be four, provided that they are not coplanar. Numerical simulations, in which sensor errors are also considered, are conducted for verification.
Fluorescent markers to study membrane retrieval in antidiuretic hormone-treated toad urinary bladder (1986)

Antidiuretic hormone (ADH) stimulation of toad urinary bladder causes fusion of intracellular vesicles called aggrephores with the apical plasma membrane of granular cells. Aggrephores contain intramembrane particle aggregates whose appearance in the apical membrane is believed to produce a large increase in its water permeability. ADH removal (ADH washout) is thought to cause the retrieval of aggrephores into granular cell cytoplasm. We studied granular cell uptake of dextran and horseradish peroxidase conjugated with fluorescein, rhodamine, or both during ADH washout. Granular cell uptake of fluorescent dextran was dependent on prior exposure to ADH, a linear function of dextran concentration, and increased by a transepithelial osmotic gradient. Immediately after removal of ADH, granular cell fluorescence was finely dispersed and located near the apical surface. Subsequently, it coalesced into larger bodies. This change was most apparent when a single bladder was subjected to two cycles of ADH stimulation and removal using a dextran containing a different fluorophore for each cycle. The ultrastructural correlate for these fluorescent patterns was identified using rhodamine-labeled horseradish peroxidase. Electron microscopy showed that after detachment from the apical membrane, label was initially in tubular-shaped vesicles near the apical surface. Later, these vesicles clustered near multivesicular bodies and transferred their label to these structures. These tubular vesicles closely resemble the morphology of aggrephores visualized by freeze-fracture electron microscopy. We conclude that these fluorescent compounds can be used as markers for the luminal contents of membrane retrieved during ADH washout and allow detailed study of its intracellular processing.
Structure of a simple but effective bus fleet management system (2005)

This paper describes the structure of an installed prototype real-time bus fleet management system. The automatic vehicle monitoring and control (AVMC) system is composed from three modules (a) the in-vehicle communications, (b) centralised communication network, and (c) route management computer system. Here we report on the simplicity and efficacy of the system.
Pathophysiology of scleroderma: an update (1998)

Scleroderma is a connective tissue disorder resulting in a progressive fibrosis of skin and internal organs. The genetic background is not clear. The microvascular system is one of the first targets involved (damage of capillaries, enhanced expression of adhesion molecules interacting with lymphocytes, perivascular infiltrates as starting points for tissue fibrosis). The immune system is unbalanced (selection of T-cell subpopulations, elevated serum levels of several cytokines, occurrence of autoantigens to topoisomerase I, centromeric proteins and RNA polymerases). As far as autoimmunity is concerned the triggering autoantigen is still unknown. Development of connective tissue fibrosis is prominent (subpopulations of fibroblasts with disturbed regulation of collagen turnover by TGF-beta, CTGF and collagen receptors (alpha1beta1, alpha2beta1)). Investigation of pathophysiology of scleroderma is effected by monitoring the serum levels for soluble mediators, by cell culture studies of affected and non-affected fibroblasts and EC, by studying environmentally induced forms of scleroderma and by studies using animal models.
A New Polyphase Current-Mode Filter Using Digitally-Programmable CCCII (2006)

A novel polyphase current-mode filter suitable for CMOS integrated circuit implementation is presented. The circuit uses two digitally-programmable current-controlled current-conveyors, MOSFETs, and two grounded capacitors. The proposed circuit can be operated from a low power supply voltage (plusmn1.5 V) and its parameters enjoy low active- and passive-sensitivity. Simulation results using CMOS CCCII are included.
Decreased growth hormone levels in the catabolic phase of severe injury. (1992)

These results are consistent with less lipid mobilization and inefficient utilization of fatty acids in the elderly patients or patients who were obese who had abundant fat sources to spare. Elevation of hGH level by exogenous administration may improve the nitrogen economy and lipid mobilization, particularly so in the elderly patients or patients who were overweight. Our study supports the view that provision of adequate nutrition with daily administration of human hGH in the first week after trauma would enhance the metabolic status of the patient, resulting in reduced morbidity and earlier discharge from the hospital.
4 GHz 8x8 Switch Matrix for SDMA System (2005)

An engineering model of an on-board rearrangeable 8×8 switch matrix has been developed using 168 PIN diodes and MIC technique. The matrix shows 14±1 dB insertion loss and 40 dB isolation over the frequency range of 3.7 to 4.2 GHz.
Convected activation profiles and the measurement of visual motion (2003)

A method is developed for the measurement of short-range visual motion in image sequences, making use of the motion of image features such as edges and points. Each feature generates a Gaussian activation profile in a spatiotemporal neighborhood of specified scale around the feature itself; this profile is then convected with motion of the feature. The authors show that image velocity estimates can be obtained from such dynamic activation profiles using a modification of familiar gradient techniques. The resulting estimators can be formulated in terms of simple ratios of spatiotemporal filters (i.e. receptive fields) convolved with image feature maps. A family of activation profiles of varying scale must be utilized to cover a range of possible image velocities. They suggest a characteristic speed normalization of the estimate obtained from each filter in order to decide which estimate is to be accepted. They formulate the velocity estimators for dynamic edges in 1-D and 2-D image sequences, as well as that for dynamic feature points in 2-D image sequences.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
DNA Methylation Biomarkers: Cancer and Beyond (2014)

Biomarkers are naturally-occurring characteristics by which a particular pathological process or disease can be identified or monitored. They can reflect past environmental exposures, predict disease onset or course, or determine a patient's response to therapy. Epigenetic changes are such characteristics, with most epigenetic biomarkers discovered to date based on the epigenetic mark of DNA methylation. Many tissue types are suitable for the discovery of DNA methylation biomarkers including cell-based samples such as blood and tumor material and cell-free DNA samples such as plasma. DNA methylation biomarkers with diagnostic, prognostic and predictive power are already in clinical trials or in a clinical setting for cancer. Outside cancer, strong evidence that complex disease originates in early life is opening up exciting new avenues for the detection of DNA methylation biomarkers for adverse early life environment and for estimation of future disease risk. However, there are a number of limitations to overcome before such biomarkers reach the clinic. Nevertheless, DNA methylation biomarkers have great potential to contribute to personalized medicine throughout life. We review the current state of play for DNA methylation biomarkers, discuss the barriers that must be crossed on the way to implementation in a clinical setting, and predict their future use for human disease.
Silver nanoparticle–clay composites (2010)

Composite materials of the alumino silicate minerals, kaolinite and halloysite, with silver nanoparticles have been successfully synthesised. This was achieved by a layer-by-layer deposition process in which kaolinite or halloysite was dispersed in successive solutions of the cationic polymeric linker polydiallyldimethylammonium chloride and anionic polymethacrylic acid capped silver nanoparticles. The optical properties of the metallic nanoparticles were retained in the composites and attractively coloured powders were produced. Electron microscopy revealed the silver to be nanospheres, ranging in diameter from 5–40 nm depending on the method of preparation. The chemical and physical characterisation of the resultant composites, particularly the mode of bonding between the nanoparticles and clays, was undertaken through X-ray diffraction, X-ray photoelectron spectroscopy and solid state NMR. The composites showed effective anti-microbial activity against Staphylococcus aureus bacteria.
Micronesian Migrant Health Issues in Hawaii (2009)

Increasing numbers of people from the Federated States of Micronesia and the Republic of the Marshall Islands are presenting for clinical and public health services across the U.S., especially in Hawaii. We review the impact of historical and contemporary relationships between the U.S. and these Freely Associated States on the health status and health care access of these migrants. We draw upon both epidemiological evidence and clinical experience to suggest measures to assure health care access and appropriate clinical care for these populations. We also point to potential public health measures, and indicate directions for future research.
A new approach to the X.509 framework: allowing a global authentication infrastructure without a global trust model (2002)

Isolated network are currently being integrated in order to create a universal and virtual inter-network. In this context, the existence of a common authentication infrastructure is extremely important. CCITT Recommendation X.509 defines a public key-based "Authentication Framework" in which the Directory Service can be used to provide key management facilities for open applications. We propose a new approach to X.509 comprising a modular reorganization of the overall system and mechanisms allowing the realization of a global infrastructure for the deployment of authentication-based secure services. These mechanisms aim to complete the X.509 framework so as to rectify some open issues of the approach in order to allow the support of a multitude of trust models while respecting each security domain's certificates validation criteria. We first discuss aspects related to authentication data retrieval and validation with respect to X.509. Then we give an overview of the overall approach, and emphasize its more relevant aspects and mechanisms while describing the applicability of our approach with respect to security architectures and current trust models. Finally, we conclude the paper describing the applicability of our approach in a open and heterogeneous environment.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The enhancement of enzymatic hydrolysis of lignocellulosic substrates by the addition of accessory enzymes such as xylanase: is it an additive or synergistic effect? (2011)

It was apparent that the 'blocking effect' of xylan was one of the major mechanisms that limited the accessibility of the cellulase enzymes to the cellulose. However, the synergistic interaction of the xylanase and cellulase enzymes was also shown to significantly improve cellulose accessibility through increasing fiber swelling and fiber porosity and also plays a major role in enhancing enzyme accessibility.
Destruction by Anaerobic Mesophilic and Thermophilic Digestion of Viruses and Indicator Bacteria Indigenous to Domestic Sludges (1980)

In raw sludges and in mesophilically and thermophilically digested anaerobic sludges, large variations in numbers of viruses occurred over narrow ranges of numbers of fecal coliforms, total coliforms, and fecal streptococci, demonstrating that the bacteria were poor quantitative reflectors of the numbers of the viruses detected. Mesophilic and thermophilic digestion of anaerobic sludges destroyed all three indicator bacteria more rapidly than such digestion destroyed the viruses. The relative rates for the destruction of viruses, fecal coliforms, and fecal streptococci in the digested sludges were consistent over the 17-month study. Fecal coliforms were 7 to 8 times more sensitive than the viruses to mesophilic digestion and 9 to 10 times more sensitive to thermophilic digestion. Total coliforms were even more sensitive. The rates at which fecal streptococci were destroyed by mesophilic and thermophilic digestion of anaerobic sludges approached those at which the viruses were destroyed by those processes; this suggested that the rates at which fecal streptococci in sludges are destroyed by those processes may serve as useful indicators for the rates at which viruses in sludges are destroyed by those processes.
Charging in cordless telecommunication systems (2002)

The author describes the possibility of supporting charging information transfer both to the user in a cordless telecommunication system connected to a network with advanced functionalities and in the system to which the user is connected. She describes how charging information can be handled in a system where the number of bearers and supplementary services used varies during a call. The basic procedures and calculations needed to provide a terminal with required charging information are explained. The procedure described achieves structured charging in cordless telecommunication systems. Demand for unused capacity may be avoided by setting a high cost level for unnecessary capacity.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
"Infinite Bandwidth" long slot array antenna (2005)

This work deals with the properties of a long slot array fed by an array of periodically located feeds spaced at a Nyquist interval. The study begins with the rigorous Green's function (GF) of a single long slot which was extended to an infinite array structure. After this, the input impedance properties of the array when fed by an array of /spl delta/ sources are described by simple formulas, which explicitly show a theoretically unlimited bandwidth when there is no backplane.
Absorption kinetics of rectally and orally administered ibuprofen (1989)

The bioavailability of rectally administered sodium ibuprofen solution and aluminum ibuprofen suspension was determined in eight normal subjects relative to the same treatments administered orally. The results indicate that the suspension was less bioavailable than the solution irrespective of the route of administration. Although not bioequivalent, rectally administered ibuprofen solution compared favourably with orally administered ibuprofen solution. The mean AUC and Cmax from rectal administration were 87 per cent and 62 per cent of the corresponding values achieved after oral administration. Mean residence times and peak times were 1-3 h longer with the rectal solution, indicating a slower rate of absorption. Absorption after rectal administration was zero order in some subjects while absorption after oral administration was first order. This may be due to the large differences in surface area between absorption sites. Since sodium ibuprofen solution is absorbed when given rectally, this route of administration could be used in patients unable to take oral ibuprofen.
Interleukin-33 Potentiates Bleomycin-Induced Lung Injury (2013)

The mechanisms of interstitial lung disease (ILD) remain incompletely understood, although recent observations have suggested an important contribution by IL-33. Substantial elevations in IL-33 expression were found in the lungs of patients with idiopathic pulmonary fibrosis and scleroderma lung disease, as well as in the bleomycin injury mouse model. Most of the observed IL-33 expression was intracellular and intranuclear, suggesting involvement of the full-length (fl) protein, but not of the proteolytically processed mature IL-33 cytokine. The effects of flIL-33 on mouse lungs were assessed independently and in combination with bleomycin injury, using recombinant adenovirus-mediated gene delivery. Bleomycin-induced changes were not affected by gene deficiency of the IL-33 receptor T1/ST2. Combined flIL-33 expression and bleomycin injury exerted a synergistic effect on pulmonary lymphocyte and collagen accumulation, which could be explained by synergistic regulation of the cytokines transforming growth factor-β, IL-6, monocyte chemotactic protein-1, macrophage inflammatory protein\x{2013}1α, and tumor necrosis factor-α. By contrast, no increase in the levels of the Th2 cytokines IL-4, IL-5, or IL-13 was evident. Moreover, flIL-33 was found to increase the expression of several heat shock proteins (HSPs) significantly, and in particular HSP70, which is known to be associated with ILD. Thus, flIL-33 is a synergistic proinflammatory and profibrotic regulator that acts by stimulating the expression of several non-Th2 cytokines, and activates the expression of HSP70.
Race, Urban Politics, and Educational Policy-Making in Washington, D.C. (1990)

In the District of Columbia, emphasis on desegregation was expensive in quality of schooling.