gebhart/patrepeval huggingface dataset:
A novel Structured Light method for one-shot dense reconstruction (2012)

Dense acquisition for moving scenarios represents an active field of research in Structured Light (SL). A common solution is to project a single one-shot fringe pattern, extracting depth from the phase deviation of the imaged pattern. This implies the use of a phase unwrapping algorithm, which can fail in the presence of depth discontinuities and occlusions. Our work presents a new one-shot dense pattern where De-Bruijn and Windowed Fourier Transform are combined obtaining a dense, absolute, accurate and computationally fast 3D reconstruction regarding the other existing techniques.
Coating single-walled carbon nanotubes with cadmium chalcogenides (2005)

Non-covalently functionalized single walled carbon nanotubes (SWNTs) have been coated with CdE (E = S, Se) by liquid phase deposition (LPD) from aqueous and hydrocarbon solution. The coating of individual SWNTs versus small ropes or composite structures is controlled by the use of SDS surfactant SWNTs and the relative concentration of the SWNTs and the cadmium source. Coating reactions in non-aqueous systems result in either composite formation or incomplete coatings. The CdE-SWNTs have been characterized by SEM, TEM, EDX, and Raman spectroscopy. The Raman fluoresence of the SWNTs is maintained at 90% with coatings of CdS > 5 nm.
Effects of Single Versus Combinations of Insecticides on the Development of Resistance (1985)

When house fly, Musca domestica L., populations were exposed to five insecticides (arsenite, dieldrin, malathion, methomyl, and fenvalerate) in different sequences and rotations, the development of resistance was slowed only slightly and cross-resistance was reduced compared with exposure to one insecticide. In only one population that evolved methomyl resistance was there evidence that it evolved significantly greater susceptibility to two insecticides (arsenite and fenvalerate). When a fly population was exposed to a combination of fenvalerate, a sticky trap, and a biocontrol agent (wasp parasite), it evolved resistance to fenvalerate, but not to the sticky trap or parasite. However, populations exposed to one control factor evolved resistance to the sticky trap, parasite, and fenvalerate.
A parallel algorithm for timing-driven global routing for standard cells (2002)

The timing-driven global routing problem is an extremely important and time consuming phase of any automated layout system. In this paper, by integrating high performance interconnection tree construction, wire-sizing, and switch-able segment channel optimization together, we propose an adaptive timing-driven global routing algorithm which minimizes the timing delay as well as circuit area. Our experiments on MCNC benchmarks show that our timing-driven global routing algorithm reduces the maximum path delays significantly from the global router TimberWolfSC. Based on this adaptive timing-driven global routing algorithm, a parallel algorithm on timing-driven global routing for standard cells is given. This algorithm has been implemented on an 8 processor IBM J-40 shared memory multi-processor by using the Message Passing Interface (MPI). Our experimental results show good speedup and circuit delay results for this parallel algorithm using MCNC benchmark circuits.
Correction of Hyperglycemia and Insulin Sensitivity by T-1095, an Inhibitor of Renal Na+-Glucose Cotransporters, in Streptozotocin-Induced Diabetic Rats (2000)

We investigated the effects of T-1095 (3-(benzo[b]furan-5-yl)-2',6'-dihydroxy-4'-methylpropiophenone 2'-O-(6-O-methoxycarbonyl)-beta-D-glucopyranoside), an orally active inhibitor of Na+-glucose cotransporter, on hyperglycemia and insulin resistance in skeletal muscle of streptozotocin (STZ)-induced diabetic rats. Chronic (4 weeks) administration of T-1095 as food admixture (0.01 -0.1% wt/wt) suppressed the blood glucose level without affecting the food intake and body weight. In addition, the reduced 2-deoxyglucose uptake and lactate release in the soleus muscle of STZ rat was ameliorated by chronic treatment of T-1095. These data suggest that T-1095 improves insulin sensitivity in skeletal muscle through correction of hyperglycemia and has novel therapeutic potential for treatment of diabetes mellitus through removing glucose toxicity.
Improved bond strength characterization of chemically activated direct bonding (CADB) epoxy-free bonded solid state laser materials (2010)

Chemically Activated Direct Bonding (CADB®) has become widely utilized as an epoxy-free assembly process for solid state laser crystals in high fluence and other aggressive environments. While data has been presented as to both optical and mechanical properties of these bond interfaces, previous research has hinted that sample preparation plays a large part in the final results. Surface finish of samples and any surface defects or sub-surface damage present can lead to artificially low strength values and other inconclusive results. In the current study, we prepared samples with polished surfaces to improve the accuracy of the bond strength measurements. Here we present strength data for bonded and bulk samples of common laser materials such as YAG, phosphate glass, and fused silica.
Integrating extra knowledge into word embedding models for biomedical NLP tasks (2017)

Word embedding in the NLP area has attracted increasing attention in recent years. The continuous bag-of-words model (CBOW) and the continuous Skip-gram model (Skip-gram) have been developed to learn distributed representations of words from a large amount of unlabeled text data. In this paper, we explore the idea of integrating extra knowledge to the CBOW and Skip-gram models and applying the new models to biomedical NLP tasks. The main idea is to construct a weighted graph from knowledge bases (KBs) to represent structured relationships among words/concepts. In particular, we propose a GCBOW model and a GSkip-gram model respectively by integrating such a graph into the original CBOW model and Skip-gram model via graph regularization. Our experiments on four general domain standard datasets show encouraging improvements with the new models. Further evaluations on two biomedical NLP tasks (biomedical similarity/relatedness task and biomedical Information Retrieval (IR) task) show that our methods have better performance than baselines.
T<scp>ree</scp>T<scp>alk</scp>: Composition and Compression of Trees for Image Descriptions (2014)

We present a new tree based approach to composing expressive image descriptions that makes use of naturally occuring web images with captions. We investigate two related tasks: image caption generalization and generation, where the former is an optional subtask of the latter. The high-level idea of our approach is to harvest expressive phrases (as tree fragments) from existing image descriptions, then to compose a new description by selectively combining the extracted (and optionally pruned) tree fragments. Key algorithmic components are tree composition and compression, both integrating tree structure with sequence structure. Our proposed system attains significantly better performance than previous approaches for both image caption generalization and generation. In addition, our work is the first to show the empirical benefit of automatically generalized captions for composing natural image descriptions.
Unsupervised Histopathology Image Synthesis (2017)

Hematoxylin and Eosin stained histopathology image analysis is essential for the diagnosis and study of complicated diseases such as cancer. Existing state-of-the-art approaches demand extensive amount of supervised training data from trained pathologists. In this work we synthesize in an unsupervised manner, large histopathology image datasets, suitable for supervised training tasks. We propose a unified pipeline that: a) generates a set of initial synthetic histopathology images with paired information about the nuclei such as segmentation masks; b) refines the initial synthetic images through a Generative Adversarial Network (GAN) to reference styles; c) trains a task-specific CNN and boosts the performance of the task-specific CNN with on-the-fly generated adversarial examples. Our main contribution is that the synthetic images are not only realistic, but also representative (in reference styles) and relatively challenging for training task-specific CNNs. We test our method for nucleus segmentation using images from four cancer types. When no supervised data exists for a cancer type, our method without supervision cost significantly outperforms supervised methods which perform across-cancer generalization. Even when supervised data exists for all cancer types, our approach without supervision cost performs better than supervised methods.
Angiotensin II Type 1 Receptor Antagonist Candesartan as an Angiogenic Inhibitor in a Xenograft Model of Bladder Cancer (2006)

Specific blockade of AT1R prevented bladder tumor growth by inhibiting angiogenesis. However, its antitumor effect was not due to direct toxicity. Because AT1R antagonists are widely used to treat hypertension, and a 2 mg/kg/d dose level of candesartan is clinically achievable, this AT1R antagonist could also be used to treat bladder cancer.
Programmable 2D Arrangements for Element Texture Design (2017)

This article introduces a programmable method for designing stationary 2D arrangements for element textures, namely textures made of small geometric elements. These textures are ubiquitous in numerous applications of computer-aided illustration. Previous methods, whether they be example-based or layout-based, lack control and can produce a limited range of possible arrangements. Our approach targets technical artists who will design an arrangement by writing a script. These scripts are using three types of operators: partitioning operators for defining the broad-scale organization of the arrangement, mapping operators for controlling the local organization of elements, and merging operators for mixing different arrangements. These operators are designed so as to guarantee a stationary result, meaning that the produced arrangements will always be repetitive. We show that this simple set of operators is sufficient to reach a much broader variety of arrangements than previous methods. Editing the script leads to predictable changes in the synthesized arrangement, which allows an easy iterative design of complex structures. Finally, our operator set is extensible and can be adapted to application-dependent needs.
The role of midkine and pleiotrophin in liver regeneration (2004)

MK and PTN are involved both in the inflammatory and reparative processes after partial hepatectomy, and as a whole are beneficial for liver regeneration.
[Synovectomy in rheumatoid arthritis]. (1995)

Surgical synovectomy in the treatment of rheumatoid arthritis has been performed for more than a 100 years, and yet the definite indication has not been made clear. Synovectomy has a convincing, but mostly time-limited effect on pain and articular hydrops, but the radiological progression continues almost undisturbed. Histological evaluation of the regenerating synovial membrane has now shown a tendency towards reversing to baseline within about a year. The difficulties in evaluating the operation are caused by the lack of comparable randomized studies performed on large populations, treated in a double-blind fashion and examined in cooperation between surgeon and rheumatologist.
a PSMA-Targeted Theranostic Concept and First Proof-of-Concept Human Studies (2015)

On the basis of the high and consistent expression of prostatespecific membrane antigen (PSMA) in metastatic prostate cancer (PC), the goal of this study was the development, preclinical evaluation, and first proof-of-concept investigation of a PSMA inhibitor for imaging and therapy (PSMA I&T) for 68 Ga-based PET and 177 Lu-based endoradiotherapeutic treatment in patients with metastatic and castration-resistant disease. Methods: PSMA I&T was synthesized in a combined solid phase and solution chemistry strategy. The PSMA affinity of nat Ga-/ nat Lu-PSMA I&T was determined in a competitive binding assay using LNCaP cells. Internalization kinetics of 68 Ga- and 177 Lu-PSMA I&T were investigated using the same cell line, and biodistribution studies were performed in LNCaP tumor–bearing CD-1 nu/nu mice. Initial human PET imaging studies using 68 Ga-PSMA I&T, as well as endoradiotherapeutic treatment of 2 patients with metastatic PC using 177 Lu-PSMA I&T, were performed. Results: PSMA I&T and its cold gallium and lutetium analog revealed nanomolar affinity toward PSMA. The DOTAGA (1,4,7,10-tetraazacyclododecane-1-(glutamic acid)-4,7,10-triacetic acid) conjugate PSMA I&T allowed fast and high-yield labeling with 68GaIII and 177LuIII. Uptake of 68Ga-/177Lu-PSMA I&T in LNCaP tumor cells is highly efficient and PSMA-specific, as demonstrated by competition studies both in vitro and in vivo. Tumor targeting and tracer kinetics in vivo were fast, with the highest uptake in tumor xenografts and kidneys (both PSMA-specific). First-in-human 68GaPSMA I&T PET imaging allowed high-contrast detection of bone lesions, lymph node, and liver metastases. Endoradiotherapy with 177Lu-PSMA I&T in 2 patients was found to be effective and safe with no detectable side effects. Conclusion: 68 Ga-PSMA I&T shows potential for high-contrast PET imaging of metastatic PC, whereas its 177 Lu-labeled counterpart exhibits suitable targeting and retention characteristics for successful endoradiotherapeutic treatment. Prospective studies on larger cohorts of patients are warranted and planned.
Design and development of the ATLAS central solenoid magnet (1999)

The ATLAS central solenoid magnet is being constructed to provide a magnetic field of 2 T in the central tracking part of the ATLAS detector. As a key technology for a solenoid coil as thin as possible, a high-strength aluminum stabilized superconductor has been developed, achieving a yield strength of >100 MPa at 4.2 K. This paper describes the status of the design and development of the solenoid magnet.
Novel Function of CRTH2 in Preventing Apoptosis of Human Th2 Cells through Activation of the Phosphatidylinositol 3-Kinase Pathway (2009)

It is now well established that interaction of PGD(2) with chemoattractant receptor- homologous molecule expressed on Th2 cells (CRTH2) promotes chemotaxis and proinflammatory cytokine production by Th2 lymphocytes. In this study we show a novel function of CRTH2 in mediating an inhibitory effect of PGD(2) on the apoptosis of human Th2 cells induced by cytokine deprivation. This effect was mimicked by the selective CRTH2 agonist 13,14-dihydro-15-keto-PGD(2), inhibited by the CRTH2 antagonists ramatroban and TM30089, and not observed in CRTH2-negative T cells. D prostanoid receptor 1 (DP(1)) or the thromboxane-like prostanoid (TP) receptor did not play a role in mediating the effects of PGD(2) on the apoptosis of Th2 cells because neither the DP(1) antagonist BW868C nor the TP antagonist SQ29548 had any effect on the antiapoptotic effect of PGD(2). Apoptosis of Th2 cells induced by Fas ligation was not suppressed by treatment with PGD(2), illustrating that activation of CRTH2 only inhibits apoptosis induced by cytokine deprivation. Treatment with PGD(2) induced phosphorylation of Akt and BAD, prevented release of cytochrome c from mitochondria, and suppressed cleavage of caspase-3 and poly(ADP-ribose) polymerase in Th2 cells deprived of IL-2. The PI3K inhibitor LY294002 blocked the effect of PGD(2) both on the signaling events and on the apoptotic death of Th2 cells. These data suggest that in addition to promoting the recruitment and activation of Th2 cells, PGD(2) may also impede the resolution of allergic inflammation through inhibiting apoptosis of Th2 cells.
General-purpose optical pattern recognition image processors (1994)

A general-purpose programmable optical image processor architecture is described. A correlator architecture is used with different filter functions employed to implement a variety of different operations required in the different levels of computer vision. We consider input scenes with a number of objects present in clutter with a number of different object classes, distortions, and contrasts. The system locates all objects and identifies the class of each. The optical image processing operations performed include morphological low-level nonlinear functions, detection of candidate regions of interest, fusion of correlation outputs to reduce false alarms, image enhancement, and feature extraction. The optical correlation filters to realize each operations, examples of each, and real-time optical correlator hardware are described.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Angular truncation errors in integrating nephelometry (2003)

Ideal integrating nephelometers integrate light scattered by particles over all directions. However, real nephelometers truncate light scattered in near-forward and near-backward directions below a certain truncation angle (typically 7°). This results in truncation errors, with the forward truncation error becoming important for large particles. Truncation errors are commonly calculated using Mie theory, which offers little physical insight and no generalization to nonspherical particles. We show that large particle forward truncation errors can be calculated and understood using geometric optics and diffraction theory. For small truncation angles (i.e., &lt;10°) as typical for modern nephelometers, diffraction theory by itself is sufficient. Forward truncation errors are, by nearly a factor of 2, larger for absorbing particles than for nonabsorbing particles because for large absorbing particles most of the scattered light is due to diffraction as transmission is suppressed. Nephelometers calibration procedures are also discussed as they influence the effective truncation error.
The Effect of Different Plasma Treatments on the Sheet Resistance of Sol-gel ITO and ATO Thin Films (2002)

Single and multilayer transparent conductive ITO and ATO films were prepared by the sol-gel dip coating process. Each ITO and ATO thin film layer was fired at 550±C in a conventional furnace for half and hour. The thickness of the coatings was measured with a surface profiler. The sheet resistance of the ITO and ATO thin films decreased as the number of layers increased. The effects of different plasma treatments on sheet resistance of the ITO and ATO thin films were studied as a function of time. Changes in sheet resistance were measured by a linear four-point probe method. It was found that an Ar-plasma treatment increased the electrical conductivity of ITO thin films, but the other gas plasma treatment decreased the electrical conductivity of the ITO and ATO thin films. PACS. 73.61.-r – Electrical properties of specific thin films and layer structures. I.
Intrinsic optical imaging of stimulus-modulated physiological responses in amphibian retina (2008)

We demonstrated near-infrared light imaging of stimulus-modulated physiological activities in an isolated frog retina using transient intrinsic optical responses (TIORs). While low-strength visible-light stimuli evoked TIORs with positive polarity, strengthened stimuli elicited additional negative TIORs. Our experimental study and physiological analysis suggest that the negative TIORs are associated with photoreceptor response, and the positive TIORs result primarily from dynamic changes of postphotoreceptor response during retinal activation. In coordination with the sophisticated design of visible-light stimulation protocols, optical imaging of TIORs promises an important application for noninvasive assessment of retinal photoreceptor and inner neurons.
Scheduling task parallelism on multi-socket multicore systems (2011)

The recent addition of task parallelism to the OpenMP shared memory API allows programmers to express concurrency at a high level of abstraction and places the burden of scheduling parallel execution on the OpenMP run time system. This is a welcome development for scientific computing as supercomputer nodes grow "fatter" with multicore and manycore processors. But efficient scheduling of tasks on modern multi-socket multicore shared memory systems requires careful consideration of an increasingly complex memory hierarchy, including shared caches and NUMA characteristics. In this paper, we propose a hierarchical scheduling strategy that leverages different methods at different levels of the hierarchy. By allowing one thread to steal work on behalf of all of the threads within a single chip that share a cache, our scheduler limits the number of costly remote steals. For cores on the same chip, a shared LIFO queue allows exploitation of cache locality between sibling tasks as well between a parent task and its newly created child tasks. We extended the open-source Qthreads threading library to implement our scheduler, accepting OpenMP programs through the ROSE compiler.
Regulation of Cell Migration by Sphingomyelin Synthases: Sphingomyelin in Lipid Rafts Decreases Responsiveness to Signaling by the CXCL12/CXCR4 Pathway (2012)

Sphingomyelin synthase (SMS) catalyzes the formation of sphingomyelin, a major component of the plasma membrane and lipid rafts. To investigate the role of SMS in cell signaling and migration induced by binding of the chemokine CXCL12 to CXCR4, we used mouse embryonic fibroblasts deficient in SMS1 and/or SMS2 and examined the effects of SMS deficiency on cell migration. SMS deficiency promoted cell migration through a CXCL12/CXCR4-dependent signaling pathway involving extracellular signal-regulated kinase (ERK) activation. In addition, SMS1/SMS2 double-knockout cells had heightened sensitivity to CXCL12, which was significantly suppressed upon transfection with the SMS1 or SMS2 gene or when they were treated with exogenous sphingomyelin but not when they were treated with the SMS substrate ceramide. Notably, SMS deficiency facilitated relocalization of CXCR4 to lipid rafts, which form platforms for the regulation and transduction of receptor-mediated signaling. Furthermore, we found that SMS deficiency potentiated CXCR4 dimerization, which is required for signal transduction. This dimerization was significantly repressed by sphingomyelin treatment. Collectively, our data indicate that SMS-derived sphingomyelin lowers responsiveness to CXCL12, thereby reducing migration induced by this chemokine. Our findings provide the first direct evidence for an involvement of SMS-generated sphingomyelin in the regulation of cell migration.
A Li–O2/CO2 battery (2011)

A new gas-utilizing battery using mixed gas of O(2) and CO(2) was developed and proved its very high discharge capacity. The capacity reached three times as much as that of a non-aqueous Li-air (O(2)) battery. The unique point of the battery is expected to be the rapid consumption of superoxide anion radical by CO(2) as well as the slow filling property of the Li(2)CO(3) in the cathode.
The effects of exogenous l-carnitine on lipid peroxidation and tissue damage in an experimental warm hepatic ischemia-reperfusion injury model (2007)

In this experimental study, administration of exogenous l-carnitine was associated with significantly decreased lipid peroxidation in plasma and liver tissue when administered prior to a TWHIR procedure. In addition, l-carnitine seemed to be more effective with regard to decreasing lipid peroxidation in liver tissue when administered before warm hepatic ischemia. l-Carnitine was associated with significantly decreased leukocyte sequestration in plasma and liver tissue. A significant increase in TAOC was associated with l-carnitine administered prior to ischemia. These observations suggest that l-carnitine might have a protective effect against ischemia-reperfusion injury in rat liver tissue.