gebhart/patrepeval huggingface dataset:
Ultrawideband electromagnetic interference to aircraft radios (2003)

A very recent FCC Final Rule now permits marketing and operation of new products that incorporate Ultrawideband (UWB) technology into handheld devices. Wireless product developers are working to rapidly bring this versatile, powerful and expectedly inexpensive technology into numerous consumer wireless devices. Past studies addressing the potential for passenger-carried portable electronic devices (PEDs) to interfere with aircraft electronic systems suggest that UWB transmitters may pose a significant threat to aircraft communication and navigation radio receivers. NASA, United Airlines and Eagles Wings Incorporated have performed preliminary testing that clearly shows the potential for handheld UWB transmitters to cause cockpit failure indications for the air traffic control radio beacon system (ATCRBS), blanking of aircraft on the traffic alert and collision avoidance system (TCAS) displays, and cause erratic motion and failure of instrument landing system (ILS) localizer and glideslope pointers on the pilot horizontal situation and attitude director displays. This paper provides details of the preliminary testing and recommends further assessment of aircraft systems for susceptibility to UWB electromagnetic interference.
Thermal effects in three-dimensional recording by femto/nano-second pulses (2006)

Abstract not reproduced here by request of the publisher. The text is available from http://dx.doi.org/10.1117/12.641130
Computers in the central office-a primer on powering equipment from -48 V (2002)

The convergence of computing and telephony is blurring the distinction between the two worlds. It is not unusual to have computing and data networking equipment installed in telephone central offices. This means that computing equipment is being adapted to operate from the -48 VDC central office (CO) power rather than the AC mains. This paper is a primer that provides an overview of what is required to power equipment from central office power. It reviews the fundamentals of central office power and distribution, the requirements of the two major standards agencies, Bellcore and the European Telecommunications Standards Institute (ETSI), and some implementation issues when equipment must designed to operate from either central office or mains power.
Nove1 techniques for whispering-gallery-mode excitation in silica microspheres (1999)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text J. P. Laine, B. E. Little, D. Lim, and H. A. Haus, "Nove1 techniques for whispering-gallery-mode excitation in silica microspheres," in Integrated Photonics Research, OSA Technical Digest Series (Optica Publishing Group, 1999), paper RTuH4. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Methods of supersymmetry breaking (1995)

This is a review of basic ideas and mechanisms encountered in the supersymmetry breaking problem at the global level, in supergravity models, and in superstring theory.
Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol (2016)

The broad-spectrum antiviral drug Arbidol shows efficacy against influenza viruses by targeting the hemagglutinin (HA) fusion machinery. However, the structural basis of the mechanism underlying fusion inhibition by Arbidol has remained obscure, thereby hindering its further development as a specific and optimized influenza therapeutic. We determined crystal structures of Arbidol in complex with influenza virus HA from pandemic 1968 H3N2 and recent 2013 H7N9 viruses. Arbidol binds in a hydrophobic cavity in the HA trimer stem at the interface between two protomers. This cavity is distal to the conserved epitope targeted by broadly neutralizing stem antibodies and is ∼16 Å from the fusion peptide. Arbidol primarily makes hydrophobic interactions with the binding site but also induces some conformational rearrangements to form a network of inter- and intraprotomer salt bridges. By functioning as molecular glue, Arbidol stabilizes the prefusion conformation of HA that inhibits the large conformational rearrangements associated with membrane fusion in the low pH of the endosome. This unique binding mode compared with the small-molecule inhibitors of other class I fusion proteins enhances our understanding of how small molecules can function as fusion inhibitors and guides the development of broad-spectrum therapeutics against influenza virus.
Synthesis and Anti‐inflammatory Activity of Some Novel Pyrazole Derivatives of Gallic Acid (2009)

In the present study, a new series of [5‐substituted‐3‐(phenylamino)‐1 H ‐pyrazol‐1yl] (3,4,5‐trihydroxyphenyl)‐methanone (4a‐j) have been synthesized. 3, 4, 5‐Trihydroxy benzohydrazide (1) was synthesized from propyl gallate and hydrazine hydrate in presence of ethanol. Chalcones (2a‐j) were synthesized from acetanilide and various aromatic aldehydes in presence of ethanol and sodium hydroxide solution. By refluxing the compound (1) and compounds (2a‐j) in presence of ethanol yielded [5‐substituted‐3‐(phenylamino)‐4.5‐dihydropyrazol‐1yl] (3,4,5‐trihydroxy phenyl)‐methanone (3a‐j). The final compounds [5‐substituted‐3‐(phenylamino)‐1 H ‐pyrazol‐1yl] (3,4,5‐trihydroxyphenyl)‐methanone (4a‐j) were synthesized by treating compounds (3a‐j) with bromine water. The synthesized compounds have been characterized by IR, 1 HNMR and Mass spectral data. The compounds were evaluated for in vivo anti‐inflammatory activity by carrageenan induced paw edema test. In general all compounds were found to exhibit good anti‐inflammatory activity.
Removing Distortions Caused by Water Velocity Variations – Method for Dynamic Correction (2003)

G-42 REMOVING DISTORTIONS CAUSED BY WATER VELOCITY VARIATIONS – METHOD FOR DYNAMIC CORRECTION Abstract 1 Physical changes in ocean properties may occur during marine acquisition that can cause variations in water velocity. The result is a dynamic difference in traveltimes between overlapping infill data acquired at a later date. Such timing discrepancies may prevent accurate merging and imaging of the data. Unfortunately classical wave-equation solutions to this problem are typically impractical for 3D marine geometries. We present an approximate version of wave-equation layer replacement that addresses the temporal errors in data from Nova Scotia. Introduction. During marine acquisition deficiencies in
Polyamines adsorbed onto silica gel: A Raman microprobe analysis (1997)

Polyamine [especially poly(ethylenimine) and poly(4-vinylpyridine)] adsorption onto silica gels for chromatography and water-decontamination experiments, using a Raman microprobe, is reviewed. First, the bare silica are characterized. Then, the polyamines and the adsorbed polyamines spectra are compared. We show that polyamine adsorption onto silica occurs with two kinds of polymer populations: chemisorbed (trains due to important interactions between silanol and the nitrogen atom) and physisorbed (multilayers) polymer. The modifications of chemisorbed polymer bands are stronger than are the physisorbed ones. © 1997 John Wiley & Sons, Inc. J Appl Polm Sci 65:871–882, 1997
Development of a multiple internal control for clinical diagnostic real-time amplification assays (2006)

A major pitfall in most published genomic amplification methods for the detection and identification of human pathogens is that they do not include an internal amplification control in order to achieve an acceptable level of confidence for the absence of false-negative results. By applying composite primer technology, a single multiple internal amplification control DNA molecule was constructed to detect and quantify the hepatitis B virus, human polyomavirus, Epstein-Barr virus, Toxoplasma gondii and cytomegalovirus using real-time PCR. The multiple internal amplification control contains all forward and reverse primer binding regions targeted in the five distinct duplex PCRs, but with a unique probe hybridization site. Multiple internal amplification control detection sensitivity, assessed by Probit analysis, was 58 copies per PCR, associated with an extremely wide dynamic range (8 log(10) units). Moreover, in testing 614 patient samples, PCR inhibition occurred at a frequency of 0-8.8%. Similar multiple internal amplification controls for quantitative PCR-based assays could be designed to accommodate any infectious profiles in a particular institution as they are easy to make and inexpensive.
Anticorrosion: Oil‐Impregnated Nanoporous Oxide Layer for Corrosion Protection with Self‐Healing (Adv. Funct. Mater. 15/2017) (2017)

In article number 1606040, Chang-Hwan Choi and co-workers develop a solvent exchange method that allows the full impregnation of oil into nanopores of anodized aluminum. The nanoporous oxide layer with fully and stably entrained oil shows significantly enhanced corrosion resistance and water-repellency with great durability and self-healing, which is of great significance in many applications such as naval systems.
340. The carrageenan system of polysaccharides. Part I. The relation between the κ- and λ-components (1963)

D. A. Rees, J. Chem. Soc., 1963, 1821 DOI: 10.1039/JR9630001821
Radioprotectors : chemical, biological, and clincial perspectives (1998)

Chemical Aspects of Radioprotection Introduction, E.A. Bump History of Radioprotector Development, W. Foye The Mechanisms of Radioprotection by Non-Protein Sulfhydryls: Glutathione, Cysteine, and Cysteamine, C. Koch Aminothiols, D. Murray Stable Free Radicals As Radiation Protectors, S.M. Hahn, C.M. Krishna, and J.B. Mitchell Radioprotection by Superoxide Dismutase, R.M. Das DNA-Binding Bibenzimidazoles As Radioprotectors, R.F. Martin Protection against Radiation Damage to DNA Bases, A. Laayoun, J. Lhomme, M. Berger, and J. Cadet Biological Perspectives of Radioprotection Introduction, W.F. Blakely, J.F. Weiss, and E.A. Bump Eicosanoid-Induced Radioprotection and Chemoprotection: Laboratory Studies and Clinical Applications, W.R. Hanson Immunomodulators and Cytokines: Their Use in the Mitigation of Radiation-Induced Hemopoietic Injury, M.L. Patchen Modulation of the Radiation Response by Cytokines, R. Neta Radiation-Induced Apoptosis in Lymophoid Cells: Induction, Prevention, and Molecular Mechanisms, N. Ramakrishnan, J.F. Kalinich, and D.E. McClain Modulation of Radiation-Induced Apoptosis, S.T. Palayoor, R.E. Langley, C.N. Coleman, and E.A. Bump Chemoprevention with WR-2721 and Its Metabolites, J.S. Murley and D.J. Grdina Radioprotection of Normal Tissues Introduction, E.L. Travis Protection against Radiation Damage to Vascular Tissues, S.J. Braunhut Radiation Protection in the Developing Central Nervous System: Investigation of a Biological Approach, P. Mullenix Clinical Trials with Radioprotectors, K. Malaker Index
Robot juggling: implementation of memory-based learning (1994)

Issues involved in implementing robot learning for a challenging dynamic task are explored in this article, using a case study from robot juggling. We use a memory-based local modeling approach (locally weighted regression) to represent a learned model of the task to be performed. Statistical tests are given to examine the uncertainty of a model, to optimize its prediction quality, and to deal with noisy and corrupted data. We develop an exploration algorithm that explicitly deals with prediction accuracy requirements during exploration. Using all these ingredients in combination with methods from optimal control, our robot achieves fast real-time learning of the task within 40 to 100 trials.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The preparation of anthraquinones and anthracyclinones via the reaction of haloarenes and cyanophthalides under aryne-forming conditions (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe preparation of anthraquinones and anthracyclinones via the reaction of haloarenes and cyanophthalides under aryne-forming conditionsSubhash P. Khanapure, R. Thimma Reddy, and Edward R. BiehlCite this: J. Org. Chem. 1987, 52, 26, 5685–5690Publication Date (Print):December 1, 1987Publication History Published online1 May 2002Published inissue 1 December 1987https://pubs.acs.org/doi/10.1021/jo00235a007https://doi.org/10.1021/jo00235a007research-articleACS PublicationsRequest reuse permissionsArticle Views1087Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Antimalarial Activity:  The Search for Marine-Derived Natural Products with Selective Antimalarial Activity (1996)

In this short review, an approach to the isolation of potential antimalarial agents and lead compounds is outlined. A discussion of organism collection, followed by a description of biological testing and isolation methodologies, is also given. For two organisms, details of their secondary metabolite chemistry are reported. From one of these, Laurencia papillosa, the two aromatic compounds p-hydroxybenzaldehyde (1) and p-methoxybenzyl alcohol (2) were isolated. From the other, the tropical marine sponge Cymbastela hooperi, 15 diterpenes (3-17), which contain isonitrile, isothiocyanate, and isocyanate functionalities, are reported. Together with the diterpenes, three sesquiterpene hydrocarbons, 18-20, and the thiol, 21, were obtained. All structures were established by spectroscopic methods, particularly 1H-1H and 1H-13C shift-correlated 2D NMR spectroscopy and accurate mass measurement (HREIMS). The majority of isolates demonstrate significant and selective in vitro antimalarial activity. For compounds 4-17 a brief description of their possible structure-activity relationships is provided.
New synthesis method of pure Mn3O4 and its reaction mechanism. (1990)

So far, pure Mn3O4 as a raw material for Mn-Zn ferrites has been synthesized by a hydrothermal reaction of H2O and Mn. But, this method was costly because it needs high temperatures above 120°C and high pressures above 3kg/cm2. And so it was tried that the pure Mn3O4 might be synthesized at not more than 100°C and under an atmospheric pressure by addition of ammonium salts or amino-acids to water with Mn.Firstly, in N2 atmosphere, the formation rates of Mn(OH)2 were measured at various temperatures when ammonium salts or amino-acids (0.05-0.5mol/l) were added into water with Mn. Secondly, the reactions were carried out under an oxygen or air atmosphere and the reaction rates and the reaction products (Mn3O4) were examined.As the results, it has found these reaction rates were dependent on the hydrogen-ion concentration, the oxygen pressure, the variety and concentration of the additions. On this reaction, Mn was oxidized by H+ and O2, and the additions, ammonium salts or amino-acids, catalyzed this reaction. These additions complexed with Mn2+ which was produced by the redox-reaction between water and Mn, and decreased the activity of Mn2+. And also, the reaction finished for the almost same hours even when the filtrate is used again many times.By the addition of ammonium salts or amino-acids, it has become easy to synthesize Mn3O4 from metal Mn at not more than 100°C, under an atmospheric pressure and within some hours. The Mn3O4 obtained by this reaction was of high pulity, so may be applied to the additions for ferrites.
View planning for the 3D modelling of real world scenes (2000)

In recent years, several methods of reconstructing 3D scenes from range images have been proposed. Currently, the factor limiting a fully automated reconstruction process is the lack of a sufficiently scalable planning algorithm for the acquisition step. We present a technique of iteratively planning the next view for a range scanner in an initially unknown, large indoor environment. When designing an algorithm suitable for architectural environments, two main problems have to be addressed. First, an objective function has to be defined to optimise the parameters of the next view. We propose an objective function based on the analysis of occlusions which takes into account both a quality criterion and the cost of the next acquisition. Second, the parameters of the next view have to be computed efficiently for a large search space with eight degrees of freedom. Our technique exploits hardware-accelerated rendering (OpenGL) in order to perform the expensive visibility computation, which reduces the computation time of one planning step to a few minutes. Results are shown for two large indoor scenes-an artificial scene and a real world room-with numerous self occlusions.
The illustrated digital imaging dictionary (1998)

From the Publisher:
This book is heavily illustrated and covers 500-600 terms. Definitions will vary in length from a sentence to several pages. A small portion of the definitions will be must-know computer terms,which the Grottas clearly define and illustrate for their unique readership. The bulk of the book,however,will focus on words germane to digital imaging,such as scanner,gamma curve,etc. This book is suitable for both advanced and novice readers.
Structure of membranolide, a diterpene from the Antarctic Sponge Dendrilla membranosa (1990)

M r = 276"24, orthorhombic, P2~212~, a = 18-48 (1), b = 9.52 (1), c = 7.55 (1) A, V = 1328.27/~3,Z = 4, Dx = 1.380 g cm-3, a(Mo Ka) =0.7107/~, /x=0.69cm-~,F(000)=576, T= 290 K, R
Activation of p38 Mitogen-Activated Protein Kinase Drives Dendritic Cells to Become Tolerogenic in<i>Ret</i>Transgenic Mice Spontaneously Developing Melanoma (2009)

Our data show a critical role of constitutively activated p38 MAPK in the acquirement of tolerogenic pattern by DCs during melanoma progression that contributes to the suppression of antitumor T-cell immune responses. We suggest that new strategies of melanoma immunotherapy can include inhibitors of p38 MAPK activity in DCs.
Usefulness of the Chin Press Maneuver in Assessing the Severity of Obstructive Sleep Apnea Syndrome (2001)

Objectives: Obstructive sleep apnea syndrome (OSA) is a moderately prevalent disorder. Even though much progress has been made in the diagnosis of this disorder, the cost-effectiveness of nocturnal polysomnography is undertermined and physicians and patients are still hesitant to undergo this procedure. The authors wanted to see the validity of chin press/tongue curl maneuver in estimating the severity of OSA which is easy to measure and was originally proposed by Simmons etc. by looking at the correlations between this score and the conventional respiratory disturbance indices. Methods: Forty-three sleep-related breathing disorder patients (28 OSA patients and 15 upper airway resistance syndrome (UARS) patients) who underwent investigation for posssible OSA were studied. Two conventional indices of OSA (apnea/hypopnea index (AHI) and oxygen saturation dip rate (SaO2 dips)), four other sleep variables (lowest SaO2, % of time with SaO2 (range 14-76) and their average BMI was (range 19.65-37.64). There were no significant differences in age, sex and BMI except repiratory disturbance indices and ESS (p test; =17.41, df=5, p=0.004) and measures of association (Somers' , t=4.83, p=0.000) indicated that CPS increased when the diagnosis changed from UARS to OSA. Spearman's rank correlations between CPS and SaO2 dips (R=0.83), between CPS and AHI (R=0.77) were good (p
<i>In Vitro</i> Nitrosation of Insulin A- and B-Chains (2006)

The physiological roles of insulin and nitric oxide (NO) have been recently recognized by several studies. A diversity of chemical modifications of insulin is reported both in vivo and in vitro. S-nitrosation, the covalent linkage of NO to cysteine free thiol is recognized as an important post-translational regulation in many proteins. Here we report the in vitro synthesis of an S-nitrosothiol of bovine insulin A- and B-chains. These compounds were characterized by their HPLC chromatographic behavior, monitored by UV visible spectroscopy and electron spray ionization mass spectrometry. The experimental results indicate that each A- and B-chain were S- nitrosated with only one NO group. Stability and solubility of these synthesized derivatives is described for physiological purposes. In this work, nitroso A- and B-chains of insulin were synthesized in vitro in order to better understand the possible interactions between insulin and NO that may be involved in the etiology of insulin resistance.
ΔNp63α Repression of the <i>Notch1</i> Gene Supports the Proliferative Capacity of Normal Human Keratinocytes and Cervical Cancer Cells (2010)

The p53 family member p63 is a master regulator of epithelial development. One of its isoforms, DeltaNp63alpha, is predominantly expressed in the basal cells of stratified epithelia and plays a fundamental role in control of regenerative potential and epithelial integrity. In contrast to p53, p63 is rarely mutated in human cancers, but it is frequently overexpressed in squamous cell carcinomas (SCC). However, its functional relevance to tumorigenesis remains largely unclear. We previously identified the Notch1 gene as a novel transcriptional target of p53. Here, we show that DeltaNp63alpha functions as a transcriptional repressor of the Notch1 gene through the p53-responsive element. Knockdown of p63 caused upregulation of Notch1 expression and marked reduction in proliferation and clonogenicity of both normal human keratinocytes and cervical cancer cell lines overexpressing DeltaNp63alpha. Concomitant silencing of Notch1 significantly rescued this phenotype, indicating the growth defect induced by p63 deficiency to be, at least in part, attributable to Notch1 function. Conversely, overexpression of DeltaNp63alpha decreased basal levels of Notch1, increased proliferative potential of normal human keratinocytes, and inhibited both p53-dependent and p53-independent induction of Notch1 and differentiation markers upon genotoxic stress and serum exposure, respectively. These results suggest that DeltaNp63alpha maintains the self-renewing capacity of normal human keratinocytes and cervical cancer cells partly through transcriptional repression of the Notch1 gene and imply a novel pathogenetical significance of frequently observed overexpression of DeltaNp63alpha together with p53 inactivation in SCCs.
A review of cerebral arteriovenous malformations and treatment with stereotactic radiosurgery (2014)

Introduction: Cerebral arteriovenous malformations (AVMs) have a complex natural history and the optimal treatment modality is still being elucidated. Several treatment modalities have been studied, including surgical excision, embolization, and radiation. This article will review the current definition, pathophysiology, natural history, clinical presentation, diagnosis, and treatment strategies. Methods: A review of the medical literature was done in various databases to review the current radiotherapy practices in the treatment of AVMs. Conclusions: Stereotactic radiosurgery is a safe and effective treatment option for AVM with good obliteration rates and low morbidity or mortality.