gebhart/patrepeval huggingface dataset:
Exports and firm survival: do trade regime and productivity matter? (2015)

This article aims to investigate the role of trade regime and productivity in the link between exporting and firm survival. We use firm-level data from China to examine whether exporters engaged in different trade regimes and with different levels of productivity react differently with regard to survival probability. We find that exporters engaged in all types of trade regimes have higher survival probabilities in comparison with nonexporters; however, the survival probability of exporters engaged in processing trade is less positively affected by productivity.
Radiolabelled monoclonal antibodies in oncology I. Technical aspects (1991)

The principles and technique of radioimmunoscintigraphy are described with particular reference to the choice of antibody and the radiolabel, the radiolabelling procedure and the patient protocols. The arguments in favour of using a short-lived high count rate radionuclide for radioimmunoscintigraphy are set out. Methods for labelling monoclonal antibodies with 111In, 123I or 99Tcm are described. The early image at 10 min after injection is essential as it acts as a template with which later images may be compared. In conclusion, many of the technical aspects of radioimmunoscintigraphy have been overcome and it is ready for wider application in oncology patients.
Engineering in genomics. Technical improvements in high throughput genome sequencing (1995)

High-throughput DNA sequencing of the C. elegans genome currently is ongoing at our Genome Sequencing Center (GSC) at Washington University School of Medicine in St. Louis and at the Sanger Centre in Hinxton, England. Our collaborative effort is aimed at completion of this 100 Mb genome by the end of 1998. Now just into our fifth year of sequencing, we have amassed a combined output of over 22 Mb of completed sequence. The first two years of the pilot project were spent investigating and evaluating different approaches to genome sequencing with respect to throughput, ease of associated techniques, and methods and their robustness. The resulting approach has since been used to produce almost all of the genome sequencing data for C. elegans and will, with appropriate modifications, continue to be our strategy of choice for the completion of this genome sequence and the beginning of the human genome. The basic strategy consists of three phases: a library construction phase, a production sequencing ("shotgun") phase, and a directed "finishing" phase.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Collagen cross‐links: location of pyridinoline in type I collagen (1985)

Collagen from bone, dentine and tendon (type I), all of which contain the pyridinoline cross-link at varying levels, were each digested with CNBr. The resulting peptide mixtures were resolved by gel filtration on A1.5m agarose and assayed for pyridinoline. The polymeric cross-linked peptide complex, poly alpha 1CB6 [(1980) Biochem. J. 189, 111] isolated from each of these tissues did not contain pyridinoline. Only one peptide fraction contained the pyridinoline cross-link; that identified as alpha 2CB3,5. However, this peptide showed only a small increase in Mr in its cross-linked form (approx. 2000-5000) demonstrating that pyridinoline is not involved in the formation of polymeric structures like poly alpha 1CB6. These data, considered in the light of the recent finding that pyridinoline is present in type I collagens from different sources in widely varying amounts, cast doubt on its role in collagen maturation.
Ionomycin activates electrogenic Ca2+ influx in rat thymic lymphocytes (1993)

Increases in intracellular Ca2+ concentration ([Ca2+]i) after addition of the carboxylic Ca(2+)-transporting ionophore ionomycin have been reported to be inhibited by depolarization in mouse T- and B-lymphocytes, a result attributed to effects on the plasma-membrane Ca2+ pump. The present experiments were undertaken to test the hypothesis that activation of electrogenic Ca2+ uptake, due to release of Ca2+i from intracellular pools, underlies the membrane-potential (Em)-sensitivity of ionomycin-mediated Ca2+ uptake in T-lymphocytes. To address this proposal we have compared the characteristics of Ca2+ influx induced by ionomycin with those of Ca2+ influx activated by release of Ca2+ from intracellular stores (store-regulated Ca2+ uptake, SRCU). The endosomal Ca(2+)-ATPase inhibitor thapsigargin was used to bring about loss of Ca2+ from intracellular pools. In support of this hypothesis, we report that: (1) ionomycin releases Ca2+ from a thapsigargin-sensitive endosomal pool, a pool previously demonstrated to regulate electrogenic SRCU in rat thymic lymphocytes, (2) Ca2+ and Mn2+ uptake mediated by low doses of ionomycin are inhibited by compounds previously reported to inhibit SRCU, and (3) in the absence of SRCU, ionomycin-mediated Ca2+ uptake displays no sensitivity to Em. We conclude that activation of electrogenic SRCU can adequately account for the Em-sensitivity of Ca2+ flux previously attributed to alterations in Ca(2+)-pump activity. Such a mechanism of action may underlie previous reports of electrogenic Ca2+ transport mediated by ionomycin in other tissues.
Effects of Ethanol on $Na^+-dependent$ Solute Uptake in Rabbit Renal Brush-Border Membrane Vesicles (1999)

This study was undertaken to examine the effect of ethanol on transport systems (glucose, phosphate, and dicarboxylate) in renal brush-border membrane vesicles (BBMV). Ethanol inhibited uptakes of glucose, phosphate, and succinate in a dose-dependent manner, but not the uptakes of The antiport was reduced by 8% ethanol. Kinetic analysis showed that ethanol caused a decrease in of three transport systems, leaving values unchanged. Ethanol decreased phlorizin binding, which was closely correlated with the decrease in of uptake. These results indicate that ethanol inhibits uptakes of glucose, phosphate, and dicaboxylate and that the reduction in of uptake is caused by a decrease in the number of active carrier proteins in the membrane.
Finite Difference Methods on Irregular Networks (1987)

The finite difference and finite element methods are powerful tools for the approximate solution of differential equations governing diverse physical phenomena, and there is extensive literature on th
Machine Learning for RF Slicing Using CSI Prediction in Software Defined Large-Scale MIMO Wireless Networks (2020)

In this paper, we investigate the machine learning approaches (sparse Bayesian linear regression (SBLR) and support vector machine (SVM)) for channel state information (CSI) prediction and dynamic radio frequency (RF) slicing for software defined virtual wireless networks in large-scale multi-input multi-output (MIMO) wireless networks. Specifically, a subset of the antennas of virtual wireless networks transmits pilot symbols for estimating the CSI and use the estimated CSI dataset to train and estimate the remaining channels and future CSI for virtual networks using machine learning algorithms. This helps not only to predict the CSI with least overhead and fulfills the service demands of users but also to reduce the power consumption and computation overhead in the network. Predicted CSI is leveraged for RF slicing for virtual wireless networks. Simulation results show that the proposed SBLR for predicting CSI results in lower BER and higher data rate for the wireless users. Furthermore, SBLR outperforms the other approaches when we have sparse CSI information and we need to generalize the prediction process.
Flow Cytometric Analysis of Cell Membrane Microparticles (2008)

Cell membrane microparticles (MPs) are phospholipid microvesicles shed from the plasma membrane of most eukaryotic cells undergoing activation or apoptosis. The presence of MPs is common in healthy individuals. However, an increase in their release is a controlled event and is considered a hallmark of cellular alteration. Microparticles display cell surface proteins that indicate their cellular origin. In addition, they may also express other markers, e.g., markers of cellular activation. Elevated levels of circulating MPs are associated with various vascular pathologies and their pathogenic potential has been widely documented. MPs have been analyzed in plasma and cell cultures by means of flow cytometry or solid phase assays. Here we present a three-color flow cytometric assay for immunophenotyping of MPs in plasma. This assay has been used to study elevated counts of different phenotypes of circulating endothelial MPs in several hematological and vascular diseases. A modified version of this assay can also be used for MP analysis in blood products and cell cultures.
Stretchable and Multimodal All Graphene Electronic Skin (2016)

A transparent and stretchable all-graphene multifunctional electronic-skin sensor matrix is developed. Three different functional sensors are included in this matrix: humidity, thermal, and pressure sensors. These are judiciously integrated into a layer-by-layer geometry through a simple lamination process.
New Thiol Inhibitors of Neutral Endopeptidase EC 3.4.24.11: Synthesis and Enzyme Active-Site Recognition (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew Thiol Inhibitors of Neutral Endopeptidase EC 3.4.24.11: Synthesis and Enzyme Active-Site RecognitionIsabel Gomez-Monterrey, Ann Beaumont, Patrick Nemecek, Bernard P. Roques, and Marie-Claude Fournie-ZaluskiCite this: J. Med. Chem. 1994, 37, 12, 1865–1873Publication Date (Print):June 1, 1994Publication History Published online1 May 2002Published inissue 1 June 1994https://pubs.acs.org/doi/10.1021/jm00038a016https://doi.org/10.1021/jm00038a016research-articleACS PublicationsRequest reuse permissionsArticle Views242Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Er3+ doped Y2O3 transparent ceramic for quantum memory applications (2018)

We study transparent ceramics made of erbium doped yttria, as a candidate material for quantum storage of photons in the telecom wavelength. Samples with different heat processing conditions are compared. Two different species of Er<sup>3+</sup> ions with drastically different dephasing properties are identified. In general, samples processed at lower temperature show narrower inhomogeneous and homogeneous linewidths. We also demonstrate both type I and type II waveguide in the material using a femtosecond laser, with propagation loss of 0.22 dB/mm.
Impairments of the Primary Afferent Nerves in a Rat Model of Diabetic Visceral Hyposensitivity (2015)

These observations revealed the distinctive feature of colonic neuropathy in short-term diabetic rats that is characterized by a diminished sensory innervation and a blunted mechanosensitivity of the remnant sensory nerves.
Desenvolvimento de Ferramentas Analíticas para o Rastreamento de Fontes Fecais: Acção-piloto 3 do Projecto ICREW : sumário executivo (2006)

A Agência Ambiental de Inglaterra e País de Gales assegurou o financiamento EU INTERREG IIIB de um projecto denominado ‘ICREW’ – Melhorar as Águas Costeiras e Recreativas. Pretendia-se com o projecto ajudar cinco estados-membro da UE – Reino Unido, Irlanda, França, Portugal e Espanha – a melhorar a qualidade das referidas águas e preparar a implementação de nova legislação da UE respeitante às mesmas. O projecto ICREW foi avaliado em aproximadamente €8m. e era composto por sete projectos, ou “acções piloto”. O projecto ICREW decorreu entre Abril de 2003 e Abril 2006. Uma dessas acções piloto, Acção Piloto 3, que envolvia parceiros da Irlanda, França, Portugal e RU, abordou o tema do rastreamento da fonte microbial da poluição fecal, do ponto de vista regulamentar. O seu objectivo foi “gerar uma ferramenta de trabalho que pode ser usada para distinguir as fontes de poluição que contribuem para uma amostra ambiental”.
Ex-Vivo Uses and Applications of Cytokines for Adoptive Immunotherapy in Cancer (2004)

Harnessing the power of the immune system to eliminate infection and cancer is a long-standing goal in clinical immunology. The development of a robust immune response to foreign antigen relies, in part, on communication between cellular components of the immune system. The proteins involved in governing the magnitude and longevity of an immune response are collectively called cytokines. Cytokines act directly on immune cells to induce proliferation, differentiation and tolerance, and signaling errors can lead to autoimmune disease or immune deficiency. Identification of the molecules involved in these signaling processes has allowed investigators to manipulate immune cells for therapeutic effect, both in vivo and ex vivo. While in vivo immune modulation using cytokines has produced some exciting results, the toxicity involved with systemic administration has limited their broad use in the clinic. Therefore, research has been focused on the ex vivo manipulation of immune cells for adoptive transfer to treat cancer and infection. This review will focus on the ex vivo manipulation of immune cells with particular emphasis on stimulating cytotoxic T cell responses. Adoptive transfer of ex vivo generated cell types may then be used to treat malignant and viral disease.
Preparation of high pure graphite by alkali digestion method (2004)

This paper deals with a novel new technique: alkali digestion, followed by grinding and flotation, has been attempted for the first time on the Indian graphite ore. The novelty in this method is that the quartz mineral, SiO 2 , present in the flakes, releases during thermal shock treatment and dissolves partly with sodium hydroxide. Acid cleaning washes out the other soluble minerals. By this method, a product containing a maximum of up to 98% fixed carbon (FC) is achieved with 97% recovery from a graphite concentrate containing 85% FC. This process is environment‐friendly and the product achieved is suitable for most of the industries.
Effect of Ta 2 O 5 , Nb 2 O 5 , and HfO 2 Alloying on the Transformability of Y 2 O 3 -Stabilized Tetragonal ZrO 2 (1990)

Peer Reviewed
Purification and Partial Kinetic and Physical Characterization of Two Chloroplast-Localized NADP-Specific Glutamate Dehydrogenase Isoenzymes and Their Preferential Accumulation in <i>Chlorella sorokiniana</i> Cells Cultured at Low or High Ammonium Levels (1987)

Two ammonium-inducible, chloroplast-localized NADP-specific glutamate dehydrogenase isoenzymes were purified to homogeneity from Chlorella sorokiniana. These isoenzymes were homopolymers of either alpha- or beta-subunits with molecular weights of 55,500 or 53,000, respectively. The alpha-isoenzyme was preferentially induced at low ammonium concentrations (2 millimolar or lower), whereas only the beta-isoenzyme accumulated after cells were fully induced (120 minutes) at high ammonium concentrations (29 millimolar). Purification of isoenzymes was achieved by (NH(4))(2)SO(4) fractionation, gel-filtration, anion-exchange fast protein liquid chromatography, and affinity chromatography. The alpha- and beta-isoenzymes were separated by their differential binding to Type 4 nicotinamide adenine dinucleotide phosphate-Sepharose. Both isoenzymes bound to an antibody affinity column to which purified antibody (prepared against beta-isoenzyme) was covalently attached. Peptide mapping of the subunits showed them to have a high degree of sequence homology. Both subunits were synthesized in vitro from precursor protein(s) with a molecular weight of 58,500. Although the subunits have similar chemical, physical, and antigenic properties, their holoenzymes have strikingly different ammonium K(m) values. The ammonium K(m) of the beta-isoenzyme remained constant at approximately 75 millimolar, whereas this K(m) of the alpha-isoenzyme ranged from 0.02 to 3.5 millimolar, depending upon nicotinamide adenine dinucleotide phosphate concentration.
보문 : Duplex PCR을 이용한 유제품 안에 있는 산양유와 우유의 신속한 동정에 대한 연구 (2009)

유제품에 들어 있는 우유와 산양유를 동정하기 위해 미토콘드리아의 12S rRNA 유전자를 목표로 하는 primer을 이용하는 duplex PCR 분석을 적용하였다. 소와 산양의 특이성 primer을 이용한 duplex PCR 분석은 우유와 산양유 DNA에 대해 각각 233 bp와 326 bp의 특이성 단편을 나타냈다. Duplex PCR 분석이 라벨에 표시된 성분을 확인하기 위하여 시중마트에서 구입한 15개 유제품에 적용하였다. Duplex PCR 분석 결과 4개 시유, 3개 요구르트, 1개 전지분유는 표시된 성분과 완전히 일치하였다. 그러나 7개의 조제분유 중 5개만 표시성분과 일치하고 2개 조제분유제품은 산양유와 우유가 각각 오염되어 있는 것으로 나타났다. 제안된 duplex PCR 분석은 산양유에 들어있는 우유를 0.1%까지 측정할 수 있는 민감하고 신속한 방법이다. Duplex PCR 분석은 유제품 속에 들어있는 우유와 산양유를 one-step 방법으로 동시에 탐지할 수 있다.
Structural Determinants of Phenoxazine Type Compounds Required to Modulate the Accumulation of Vinblastine and Vincristine in Multidrug-Resistant Cell Lines (1990)

Phenoxazine and seven other structurally related compounds were investigated to determine whether they would increase accumulation of Vinca alkaloids in multidrug-resistant (MDR) GC3/C1 (human colon adenocarcinoma) and KB-ChR-8-5 (HeLa variant) cell lines. Among eight compounds examined, phenoxazine caused greater accumulations of vincristine (VCR) and vinblastine (VLB) than the other chemosensitizers. The structure-activity relationship of these compounds for anti-MDR activity suggested an ideal tricyclic ring structure with a basic nitrogen atom at position 10 for modulating the accumulation of Vinca alkaloids. Addition of oxygen to position 5 of the tricyclic ring system further increased the activity, implying that a highly electronegative element with one, or more, lone pair of electrons in the nucleus opposite to heterocyclic nitrogen was a requirement for better anti-MDR activity. The relationship between the concentration of phenoxazine and the potentiation of Vinca alkaloid accumulation in comparison to verapamil was examined. For VCR in GC3/C1 cells, maximal modulation indices were: for verapamil, 1.8; phenoxazine, 8.6; and for VLB, 1.3 for verapamil compared to 3.3 for phenoxazine. In KB-ChR-8-5 cells, for VCR the maximal modulating index values were 9.0 and 4.3, respectively, and for phenoxazine and verapamil and for VLB were 5.0 and 3.7, respectively. Accumulations of VLB in GC3/C1 cells were similar in the presence of 1 microM phenoxazine or 10 mM sodium azide plus 10 mM 2-deoxyglucose. The effects of verapamil and phenoxazine on the accumulation of Vinca alkaloid were additive. Further, phenoxazine decreased the efflux of VLB by 30% in KB-ChR-8-5 cell line and 10% in GC3/C1 cells. In addition to enhancing the cytotoxicities of VCR and VLB, phenoxazine competed relatively weakly for binding to P-glycoprotein with [3H]azidopine and moderately with [3H]azidoverapamil, at equal concentrations, suggesting that the multidrug transporter may be the primary target for phenoxazine.
Organic getter materials for the removal of hydrogen and its isotopes (1990)

Herein, we describe hydrogen getter technologies developed at SNL and KCD over the past decade. The technologies are based on the irreversible removal of hydrogen by catalytic hydrogenation of unsaturated organic compounds. Different types have been developed: crystalline getters, dialkynes combined with heterogeneous catalysts; and a polymeric getter, a thermoplastic elastomer capable of reacting with hydrogen in the presence of oxygen without producing water. These materials can remove up to 300 cc (STP) of hydrogen per gram of material, and can maintain atmospheres of less than 10 ppM hydrogen. Crystalline getters for tritium and the combination hydrogen(tritium), water, and oxygen are described. The accumulation of hydrogen is usually an undesired event. Large leaks from hydrogen storage and handling facilities pose explosion hazards. Small amounts of hydrogen that may build up in sealed containers after long storage times can damage integral components. Any tritium leak is an immediate health hazard. Hydrogen scavengers or getters can avert all of these potential problems by irreversibly removing hydrogen from such environments. In this paper, we describe the development of two types of organic getters: the first is a new crystalline getter, based on 1,4-bis(phenylethynyl)benzene{sup 5} (DEB); the second is a polymeric hydrogen getter, basedmore » on styrene-butadiene copolymer.« less
Stick-slip Actuation of Electrostatic Stepper Micropositioners for Data Storage - the &#181;Walker (2006)

This paper is about the /spl mu/Walker, an electrostatic stepper motor mainly intended for positioning the data probes with respect to the storage medium in a data storage device. It can deliver forces up to 1.7 mN for ranges as large as 140 /spl mu/m. Controlling the stick-slip effects at the sliding surfaces is of central importance for reliable operation. A model is introduced to estimate the operating voltage of the actuator plate, which is an essential part of the /spl mu/Walker. Several methods to obtain displacements smaller than one nominal step (/spl ap/ 50 nm) are discussed, as well as how to increase the step repeatability and accuracy.
InP-Based High-Speed Photodetectors (2009)

This paper provides an overview on recent advances of InP-based photodetectors for high-speed fiber-optic applications, with emphasis on evanescently coupled waveguide photodiodes, balanced receivers, and distributed traveling wave photodetectors.
Dynamic remote host classification in grid computing using Clonalg (2010)

In our work, we study the efficacy of classifying registered hosts dynamically using Clonalg to classify registered hosts during job scheduling.
Optimal charging and discharging for multiple PHEVs with demand side management in vehicle-to-building (2012)

Plug-in hybrid electric vehicles (PHEVs) will be widely used in future transportation systems to reduce oil fuel consumption. Therefore, the electrical energy demand will be increased due to the charging of a large number of vehicles. Without intelligent control strategies, the charging process can easily overload the electricity grid at peak hours. In this paper, we consider a smart charging and discharging process for multiple PHEVs in a building's garage to optimize the energy consumption profile of the building. We formulate a centralized optimization problem in which the building controller or planner aims to minimize the square Euclidean distance between the instantaneous energy demand and the average demand of the building by controlling the charging and discharging schedules of PHEVs (or ‘users’). The PHEVs' batteries will be charged during low-demand periods and discharged during high-demand periods in order to reduce the peak load of the building. In a decentralized system, we design an energy cost-sharing model and apply a non-cooperative approach to formulate an energy charging and discharging scheduling game, in which the players are the users, their strategies are the battery charging and discharging schedules, and the utility function of each user is defined as the negative total energy payment to the building. Based on the game theory setup, we also propose a distributed algorithm in which each PHEV independently selects its best strategy to maximize the utility function. The PHEVs update the building planner with their energy charging and discharging schedules. We also show that the PHEV owners will have an incentive to participate in the energy charging and discharging game. Simulation results verify that the proposed distributed algorithm will minimize the peak load and the total energy cost simultaneously.