gebhart/patrepeval huggingface dataset:
Patterns and Progress in Ovarian Cancer Over 14 Years (2006)

In this large population-based study, there has been some improvement in the overall survival of women with ovarian cancers during a 14-year period. However, new treatment strategies are warranted for those with epithelial cancer and sarcomas of the ovary, given their overall poor prognosis. These results from our updated analyses might help to counsel women diagnosed with ovarian cancers.
Design of mobile augmented reality game based on image recognition (2017)

The work studied a complete set of development system for mobile augmented reality game based on combination of AR technology and RTS game. An effective image recognition strategy was proposed through SIFT feature matching algorithm. Integrated with cloud image recognition module, the response speed of image recognition module was improved by eliminating error matching point. Through optimization of the scheme and existing technologies, the improved image recognition algorithm was applied to the game system, realizing RTS game system on mobile intelligent terminal. The experimental results showed that the proposed method meets the requirement of augmented reality system in terms of efficiency and accuracy. In addition, the demand of users for information expansion can be satisfied by the method to some extent, which is more applicable than traditional augmented reality.
EphA4 promotes cell proliferation and migration through a novel EphA4-FGFR1 signaling pathway in the human glioma U251 cell line (2008)

The Eph receptor tyrosine kinases and their ephrin ligands form a unique cell-cell contact-mediated bidirectional signaling mechanism for regulating cell localization and organization. High expression of Eph receptors in a wide variety of human tumors indicates some roles in tumor progression, which makes these proteins potential targets for anticancer therapy. For this purpose, we did gene expression profiling for 47 surgical specimens of brain tumors including 32 high-grade glioma using a microarray technique. The analysis, focused on the receptor tyrosine kinases, showed that EphA4 mRNA in the tumors was 4-fold higher than in normal brain tissue. To investigate the biological significance of EphA4 overexpression in these tumors, we analyzed EphA4-induced phenotypic changes and the signaling mechanisms using human glioma U251 cells. EphA4 promoted fibroblast growth factor 2-mediated cell proliferation and migration accompanied with enhancement of fibroblast growth factor 2-triggered mitogen-activated protein kinase and Akt phosphorylation. In addition, active forms of Rac1 and Cdc42 increased in the EphA4-overexpressing cells. Furthermore, we found that EphA4 formed a heteroreceptor complex with fibroblast growth factor receptor 1 (FGFR1) in the cells and that the EphA4-FGFR1 complex potentiated FGFR-mediated downstream signaling. Thus, our results indicate that EphA4 plays an important role in malignant phenotypes of glioblastoma by enhancing cell proliferation and migration through accelerating a canonical FGFR signaling pathway.
Phase I and Pharmacokinetic Trial of Intraperitoneal Etoposide in Combination With the Multidrug-Resistance-Modulating Agent Dipyridamole (1991)

Dipyridamole synergistically enhances the sensitivity of human ovarian carcinoma cells to etoposide in vitro. We conducted a phase I trial to investigate the feasibility of using dipyridamole to selectively increase the sensitivity to etoposide of tumors confined to the peritoneal cavity. Etoposide and dipyridamole were administered as a continuous 72-hour intraperitoneal infusion to 16 patients. The maximum tolerated dose of etoposide was 175 mg/m2 per day when administered with dipyridamole at a fixed dose of 24 mg/m2 per day. Dose-limiting toxic effects were leukopenia and thrombocytopenia. No other major toxic effects were observed. The free peritoneal etoposide and dipyridamole concentrations varied with the etoposide dose rate, reaching 218.9 and 25.3 microM, respectively, at an etoposide dose rate of 175 mg/m2 per day. The free etoposide and dipyridamole concentrations attained were well within the range needed for synergistic interaction.
Multiple CMEs and large gradual SEP events (2005)

Gradual Solar Energetic Particle events (SEPs) are now believed to be associated with shocks driven by Coronal Mass Ejections (CMEs).As CMEs propagate out from the Sun, particles are accelerated at the shock front, reaching energies to 's of MeV and occasionally 's.Understanding the time intensity profiles of these gradual events and the spectra of the accelerated particles are of practical importance to, for example, manned spacecraft program since these particles are the No. 1 space-weather hazard.Recently, there are observational indications that large gradual events usually happen when two or more CMEs occur closely.In this work, we investigate particle acceleration at two close CME-driven shocks.We find that comparing to the case of a single CME-driven shock, the maximum particle energy, at the second CME-driven shock, can increase significantly due to the enhanced turbulence between the shock pairs.Implications of our calculation to the observations of gradual SEP events are discussed.
Functionalized Graphene Oxide as a New Highly Proton Conductive Composite Membrane for High Temperature PEMFCs (2011)

Abstract not Available.
Nanoparticle-mediated delivery of Neurotoxin-II to the brain with intranasal administration: an effective strategy to improve antinociceptive activity of Neurotoxin (2011)

The nanoparticles overcoated with polysorbate-80 were capable of transporting the loaded drug across the BBB after intranasal administration.
Studies of high‐frequency magnetic permeability of rod‐shaped CrO<sub>2</sub> nanoparticles (2006)

Abstract Rod‐shaped CrO 2 nanoparticles with an aspect ratio of around 8:1 were studied in this work. The high‐frequency properties (complex magnetic permeability, electric permittivity and reflection coefficient) have been measured on a composite consisting of 20 vol% of rod‐shaped CrO 2 nanoparticles in a non‐magnetic epoxy resin matrix. The intrinsic magnetic permeability was calculated using an analytical model derived from the Landau–Lifshitz–Gilbert (LLG) equation. The effective permeability of the composite consisting of rod‐shaped CrO 2 particles embedded in a nonmagnetic matrix (epoxy resin) was calculated using an effective medium theory for randomly orientated ellipsoidal inclusions. The comparison of the experimental values of the effective permeability with the analytical calculation showed that a relatively good agreement was obtained when the interparticle interactions were taken into the consideration. The results showed that CrO 2 have a natural resonance frequency at around 8 GHz. The microwave absorbing properties of the composite of rod‐shaped CrO 2 nanoparticles and epoxy resin were studied. The calculated results of reflection coefficient indicated that the rod‐shaped CrO 2 nanoparticles may be interesting for microwave absorption, particularly for the high frequency range around 10 GHz (X‐band). (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Cosolvent-Enhanced Remediation of Residual Dense Nonaqueous Phase Liquids: Experimental Investigation (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCosolvent-Enhanced Remediation of Residual Dense Nonaqueous Phase Liquids: Experimental InvestigationPaul T. Imhoff, Simon N. Gleyzer, John F. McBride, Laura A. Vancho, Itaru. Okuda, and Cass T. MillerCite this: Environ. Sci. Technol. 1995, 29, 8, 1966–1976Publication Date (Print):August 1, 1995Publication History Published online1 May 2002Published inissue 1 August 1995https://pubs.acs.org/doi/10.1021/es00008a014https://doi.org/10.1021/es00008a014research-articleACS PublicationsRequest reuse permissionsArticle Views289Altmetric-Citations107LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Cultivation of the early quail embryo: induction of embryogenesis under in vitro conditions. (1987)

Embryogenesis of the quail can be induced under in vitro conditions by avoiding drying out of the germinal area. This is attained either by covering the surface of the egg content with diluted albumen or by regulating the water loss in the incubating system by means of a membrane.
A double-deck elevator systems controller with idle cage assignment algorithm using genetic network programming (2010)

Many studies on Double-Deck Elevator Systems (DDES) have been done for exploring more e±cient algorithms to improve the system transportation capacity, especially in a heavy tra±c mode. The main idea of these algorithms is to decrease the number of stops during a round trip by grouping the passengers with the same destination as much as possible. How to dispatch idle cages, which is seldom considered in the heavy tra±c mode, becomes important when developing the controller of DDES. In this paper, we propose a DDES controller with idle cage assignment algorithm using Genetic Network Programming (GNP) for a light traffic mode, which is based on a timer and event-driven hybrid model. To verify the effeciency and effectiveness of the proposed method, some experiments have been done under a special down-peak pattern.
Conjugative transposition of Tn<i>916</i>: preferred targets and evidence for conjugative transfer of a single strand and for a double‐stranded circular intermediate (1994)

Transposition of conjugative transposons proceeds by excision and formation of a covalently closed circular intermediate that includes at its joint the six flanking bases from its previous host (coupling sequences). To elucidate the role of the coupling sequences in this process and to determine the sequence of targets used by Tn916, we studied its insertion into a plasmid following conjugation. The results differ from those previously observed when Tn916 was introduced by transformation. They suggest that only one specific strand of the transposon molecule is transferred during the conjugation event and that complementary strand synthesis produces a double-stranded transposon circle with no mismatches which serves as the reaction intermediate. Tn916 inserts preferentially at specific sites and the same targets are used when Tn916 comes from donors with different coupling sequences. An analysis of the sequences of preferred targets is presented.
A conceptual framework for computational models of Achilles tendon homeostasis (2013)

Computational modeling of tendon lags the development of computational models for other tissues. A major bottleneck in the development of realistic computational models for Achilles tendon is the absence of detailed conceptual and theoretical models as to how the tissue actually functions. Without the conceptual models to provide a theoretical framework to guide the development and integration of multiscale computational models, modeling of the Achilles tendon to date has tended to be piecemeal and focused on specific mechanical or biochemical issues. In this paper, we present a new conceptual model of Achilles tendon tissue homeostasis, and discuss this model in terms of existing computational models of tendon. This approach has the benefits of structuring the research on relevant computational modeling to date, while allowing us to identify new computational models requiring development. The critically important functional issue for tendon is that it is continually damaged during use and so has to be repaired. From this follows the centrally important issue of homeostasis of the load carrying collagen fibrils within the collagen fibers of the Achilles tendon. Collagen fibrils may be damaged mechanically-by loading, or damaged biochemically-by proteases. Upon reviewing existing computational models within this conceptual framework of the Achilles tendon structure and function, we demonstrate that a great deal of theoretical and experimental research remains to be done before there are reliably predictive multiscale computational model of Achilles tendon in health and disease.
Ice-Templated Bimodal-Porous Silver Nanowire/PDMS Nanocomposites for Stretchable Conductor (2018)

A three-dimensional (3D) bimodal-porous silver nanowire (AgNW) nanostructure with superior electrical properties is fabricated by freeze drying of AgNW aqueous dispersion with macrosized ice spheres for bimodal-porous structure. The ice sphere dispersed AgNW solution yields a 3D AgNW network at the surface of ice sphere and formation of macropores by removal of ice sphere during freeze-drying process. The resulting nanostructures exhibit excellent electrical properties due to their low electrical percolation threshold by the formation of macropores, which results in an efficient and dense 3D AgNW network with a small amount of AgNWs. The highly conductive and stretchable AgNW/poly(dimethylsiloxane) (PDMS) nanocomposites are made by impregnating the 3D porous conductive network with highly stretchable poly(dimethylsiloxane) (PDMS) matrix. The AgNW/PDMS nanocomposites exhibit a high conductivity of 42 S/cm with addition of relatively small amount of 2 wt %. The high conductivity is retained when stretched up to 120% elongation even after 100 stretching-releasing cycles. Due to high electrical conductivity and superior stretchability of AgNW/PDMS nanocomposites, these are expected to be used in stretchable electronic devices.
Comparative Evaluation of Header vs. Payload based Network Anomaly Detectors (2009)

Abstract — With the immense growth of services offered by Internet, the requirement of broadband connectivity has increased significantly in past few years. Organizations and individuals are relying heavily on the internet for their daily communication needs. Consequently, networks have become more prone to different types of network attacks. Intrusion Detection Systems (IDS) offer a method to protect networks against many such attacks. Numerous IDS have been proposed in literature, which employ different techniques to identify attack patterns as well as abrupt changes in network traffic flows. Anomaly detection is a type of Intrusion Detection corresponding to a suite of techniques that can be used to identify novel or “zero-day ” attacks against computers and network infrastructure. Different Anomaly-based Intrusion Detection Systems (ADS) work on different principles e.g., a few take into account the packet headers only, where as others operate on payload as well as packet headers. In this paper we evaluate six different ADS; three of them work on packet header only, while remaining three works on both header and payload. We aim to provide a conclusive comparison of these ADS (header only or both header and payload) in terms of accuracy, complexity and detection delay to highlight factors that must be considered while designing IDS in future. The comparison is performed using two real-world labeled datasets to enable cross-reference for future research in this field. In the end of this paper we will conclude that anomaly detectors which work on both header and payload perform better than those ADS which consider only header for intrusion detection. Index Terms—Anomaly detection, Comparative evaluation, Worms, Zero-day attacks.
Secure Two-Party Multi-Dimensional Vector Comparison Protocol (2009)

Secure two-party vector dominance means that the two sides of the computation want to judge whether their vectors have the dominance relation securely, a new problem which is called multi-dimensional vector comparison problem is proposed based on the vector dominance in this paper, it can be applied in many commercial areas, such as auction, bidding and so on. Two solutions are provided for this problem, using multiplication protocol and scalar products protocol respectively. Furthermore, we introduce the random algorithm to solve the problem, analyze the security, correctness and complexity, point out the differences between these two methods, and simulate by experiments.
Robustness analysis of multichannel Wiener filtering and generalized sidelobe cancellation for multimicrophone noise reduction in hearing aid applications (2005)

For small-sized arrays such as hearing aids, noise reduction is obtained at the expense of an increased sensitivity to errors in the assumed signal model, i.e., microphone mismatch, variations in speaker and microphone positions, reverberation. However, the noise reduction algorithm should still be robust, i.e., insensitive to small signal model errors. In this paper, we evaluate the robustness of the Generalized Sidelobe Canceller (GSC) and a recently developed Multichannel Wiener Filtering (MWF) technique for hearing aid applications both analytically and experimentally. The analysis reveals that robustness of the GSC is especially crucial in complicated noise scenarios and that microphone mismatch is particularly harmful to the GSC, even when the adaptive noise canceller is adapted during noise only. Hence, a constraint on the noise sensitivity of the GSC is essential, at the expense of less noise reduction. The MWF on the other hand, is not affected by microphone mismatch and has a potential benefit over the robust GSC with noise sensitivity constraint. However, the MWF is sensitive to the estimation accuracy of the second order statistics of speech and noise so that its benefit may be lost in nonstationary noise scenarios.
An Iterative Regularization Method for Total Variation-Based Image Restoration (2005)

We introduce a new iterative regularization procedure for inverse problems based on the use of Bregman distances, with particular focus on problems arising in image processing. We are motivated by the problem of restoring noisy and blurry images via variational methods by using total variation regularization. We obtain rigorous convergence results and effective stopping criteria for the general procedure. The numerical results for denoising appear to give significant improvement over standard models, and preliminary results for deblurring/denoising are very encouraging.
HLA-G is a potential tumor marker in malignant ascites. (2003)

Our findings suggest that measurement of sHLA-G is a useful molecular adjunct to cytology in the differential diagnosis of malignant versus benign ascites.
Parallel Processing of Substrate Correlates with Greater Functional Stability in Methanogenic Bioreactor Communities Perturbed by Glucose (2000)

Parallel processing is more stable than serial processing in many areas that employ interconnected activities. This hypothesis was tested for microbial community function using two quadruplicate sets of methanogenic communities, each set having substantially different populations. The two communities were maintained at a mean cell residence time of 16 days and a mean glucose loading rate of 0.34 g/liter-day in variable-volume reactors. To test stability to perturbation, they were subjected to an instantaneous glucose pulse that resulted in a 6.8-g/liter reactor concentration. The pattern of accumulated products in response to the perturbation was analyzed for various measures of functional stability, including resistance, resilience, and reactivity for each product. A new stability parameter, "moment of amplification envelope," was used to compare the soluble compound stability. These parameters indicated that the communities with predominantly parallel substrate processing were functionally more stable in response to the perturbation than the communities with predominantly serial substrate processing. The data also indicated that there was good replication of function under perturbed conditions; the degrees of replication were 0.79 and 0.83 for the two test communities.
Differential DNA methylation profiles of infants exposed to maternal asthma during pregnancy (2013)

In an Australian study population, exposure to maternal asthma during pregnancy is associated with differential methylation profiles of infants' peripheral blood DNA, which may act as risk factors for future asthma development.
<b>Cyclopropylcarbinyllithium</b> (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCyclopropylcarbinyllithiumPeter T. Lansbury and Victor A. PattisonCite this: J. Am. Chem. Soc. 1963, 85, 12, 1886–1887Publication Date (Print):June 1, 1963Publication History Published online1 May 2002Published inissue 1 June 1963https://pubs.acs.org/doi/10.1021/ja00895a053https://doi.org/10.1021/ja00895a053research-articleACS PublicationsRequest reuse permissionsArticle Views106Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Preparation of all-oxide ferromagnetic/ferroelectric/ superconducting heterostructures for advanced microwave applications (1999)

As candidates for functional layers, 3d transition metal oxides with perovskite structures show some interesting properties, such as ferromagnetism, ferroelectricity and superconductivity. Accordingly, combinations of these properties can be used to create new tunable microwave devices. Ferromagnetic/ferroelectric/superconducting multistructures, such as La0.70Sr0.30MnO3 (LSMO)/Pb(Zr0.52Ti0.48)O3 (PZT)/YBa2Cu3O7-y (YBCO) and YBCO/PZT/LSMO, have been fabricated by ArF excimer laser deposition on LaSrGaO4 (LSGO) [001] and (La0.30Sr0.70)(Al0.65Ta0.35)O3 (LSAT) [001] substrates. The resulting trilayer films have a highly c-axis oriented structure. Epitaxial YBCO films formed on PZT/LSMO//LSAT have a zero-resistance temperature of 87 K. Moreover, D-E and M-H hysteresis loop are observed for the LSMO/PZT/YBCO//LSGO structure using a conventional Sawyer-Tower circuit and a superconducting quantum interference device (SQUID). The remanent polarization and coercive field of the PZT layer are found to be 19 µC cm-2 and 275 kV cm-1 at 70 K, respectively. The remanent magnetic moment and coercive magnetic field are about 2.6 µB/site and 50 Oe respectively at 78 K. Furthermore, the microwave surface resistance (RS) (22 GHz) of the YBCO film in the YBCO/PZT/LSMO structure was 1.32 m at 77 K. These results suggest that LSMO/PZT/YBCO structures are favourable for use in superconducting microwave applications such as tunable phaseshifters and filters.