gebhart/patrepeval huggingface dataset:
Custom, Integrated, Pneumatic, Rotary Actuator for an Active Ankle-Foot Orthosis (2010)

End-use objects produced via additive manufacturing (AM) are on the rise and new applications in the fluid power industry are emerging. Recently, a custom, pneumatic, rotary actuator was been designed and additively manufactured for integration into an active ankle-foot orthosis that is being developed in the National Science Foundation’s Center for Compact and Efficient Fluid Power. All necessary plumbing, between the valves and vanes, is integrated into the additively-manufactured housing of the actuator; and, the silicone translating seals were vacuum-transfer molded using additively-manufactured molds and inserts. This nonconventional actuator has more theoretical torque, and weighs less, than the off-the-shelf component that it replaced. Further development will reduce seal leakage, and optimize designs for additional mass reduction. Results-to-date are presented, in addition to several other examples of the growing use of AM in the fluid-power industry.
[1,2]-Wittig Rearrangement of Acetal Systems: A Highly Stereocontrolled Conversion of <i>O</i>-Glycosides to <i>C</i>-Glycosides (1996)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXT[1,2]-Wittig Rearrangement of Acetal Systems: A Highly Stereocontrolled Conversion of O-Glycosides to C-GlycosidesKatsuhiko Tomooka, Hiroshi Yamamoto, and Takeshi NakaiView Author Information Department of Chemical Technology Tokyo Institute of Technology, Meguro, Tokyo 152, JapanCite this: J. Am. Chem. Soc. 1996, 118, 13, 3317–3318Publication Date (Web):April 3, 1996Publication History Received27 November 1995Published online3 April 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/ja953933hhttps://doi.org/10.1021/ja953933hrapid-communicationACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views1912Altmetric-Citations80LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (3)»Supporting Information Supporting Information SUBJECTS:Lactones,Mixtures,Pharmaceuticals,Rearrangement,Stereospecificity Get e-Alerts
Fine coal-refuse slurry dewatering. Report of Investigations/1981 (1981)

The Bureau of Mines, in cooperation with Washington Irrigation and Development Co. (WIDCO), evaluated the dewatering of fine coal-refuse slurry using chemicals and various types and combinations of drains in natural earth impoundments. About 40 lb of lime and 2 lb of polymer per ton of dry solids were mixed with the underflow from the preparation-plant thickener. Clear, free water was immediately liberated from the slurry. The percent solids by weight of the slurry increased from about 17 to 30 immediately, and after 5 days increased to 45 wt-pct. This indicates a threefold reduction in total volume after 5 days from 172 cu ft/ton solids originally to 56 cu ft/ton solids.
Avoiding spurious reflections from shiny surfaces on a 3D real-time machine vision inspection system (2002)

Spurious reflections from shiny surfaces are one of the main problems in machine vision inspection systems based on triangulation of structured light This paper presents a practical way to solve this problem using reference points developed off-line and stored in a Look Up Table (LUT). First, a non-contact real-time 3D machine vision inspection system is described. Its accuracy is +/-2 /spl mu/m using a structured laser light sheet imaged by a machine vision camera. Based on the triangulation method, the system uses a single image and a fixed sheet of light combined with known position of the object being inspected The inspection locations on the object's surfaces are created off-line. To increase the inspection speed and eliminate the influence of spurious reflections from shiny surfaces, inspection of subsequent objects checks only those previously found locations. The system's repeatability depends on improving the laser centroid algorithm and avoiding reflections from shiny surfaces, A new algorithm is presented which calculates the center of the diffusely reflected laser line using a machine vision camera. The system verifies that this algorithm is more robust and accurate than traditional ones, To avoid spurious reflections from shiny surfaces, the object is first scanned off-line, finding as many points as possible where the laser line crosses the object Then the 3-space locations of these points are found using the standard triangulation algorithm. Next the object's surfaces are reconstructed using the scanned 3D points, breaking the object into various simple surface primitives such as planes, cylinders, cones, spheres and splined surfaces. The influence of the spurious reflections from shiny surfaces is eliminated by deleting those points which do not fall on the constructed surfaces. Based on the reconstructed surfaces, the system creates the object's inspection locations which is used later for fast and accurate on-line inspection,.
Stability of Longitudinal Oscillations with Pressure and Velocity Coupling in a Solid Propellant Rocket (1970)

Abstract Of the various unstable motions observed in solid propellant rocket chambers, the most troublesome currently are those involving oscillatory motions parallel to the axis. Such instabilities are found to arise particularly in larger rockets using propellants which contain aluminum. The problem is formulated here in one-dimensional form and solved for the case of small amplitude standing waves. Both pressure and velocity coupling may be accommodated, although the proper description of the response function for velocity coupling is not yet known. In addition to several special cases, the stability boundary is discussed for a straight chamber having variable cross section. The influences of the mean flow field, the nozzle, particulate matter, and motions of the solid propellant grain are taken into account.
LRRK2 Kinase Regulates Synaptic Morphology through Distinct Substrates at the Presynaptic and Postsynaptic Compartments of the<i>Drosophila</i>Neuromuscular Junction (2010)

Mutations in leucine-rich repeat kinase 2 (LRRK2) are linked to familial as well as sporadic forms of Parkinson's disease (PD), a neurodegenerative disease characterized by dysfunction and degeneration of dopaminergic and other types of neurons. The molecular and cellular mechanisms underlying LRRK2 action remain poorly defined. Here, we show that LRRK2 controls synaptic morphogenesis at the Drosophila neuromuscular junction. Loss of Drosophila LRRK2 results in synaptic overgrowth, whereas overexpression of Drosophila LRRK or human LRRK2 has opposite effects. Alteration of LRRK2 activity also affects neurotransmission. LRRK2 exerts its effects on synaptic morphology by interacting with distinct downstream effectors at the presynaptic and postsynaptic compartments. At the postsynapse, LRRK2 interacts with the previously characterized substrate 4E-BP, an inhibitor of protein synthesis. At the presynapse, LRRK2 phosphorylates and negatively regulates the microtubule (MT)-binding protein Futsch. These results implicate synaptic dysfunction caused by deregulated protein synthesis and aberrant MT dynamics in LRRK2 pathogenesis and offer a new paradigm for understanding and ultimately treating PD.
Fullerenes: Synthesis, Separation, Characterization, Reaction Chemistry, and Applications—A Review (1995)

Abstract The recently discovered third allotrope of carbon, the fullerenes, are a subject of very active research, particularly for chemists. They have a closed-cage structure, made by interlocking pentagonal and hexagonal panels, and are the only soluble form of carbon. In this review an attempt has been made to summarize ongoing fullerene research. The review covers methods of fullerene production and separation, mechanisms leading to closed-cage structure formation, structural characterization, reaction chemistry, and applications of this novel material. The emerging directions of research are also discussed.
Silica Nanoparticles as Adhesives for Biological Tissues? Re‐Examining the Effect of Particles Size, Particle Shape, and the Unexpected Role of Base (2017)

Abstract Development of new, effective, and patient‐friendly adhesives for biological tissues is important for medical and surgical practices such as bleeding control and organ repairing. While some commercially available silica nanoparticles such as LUDOX SM‐30 have shown adhesive properties for biological tissues, the role of inorganic base present in the adhesive properties of the silica nanoparticles has not been examined. Moreover, it remained unclear how the size and the shape of silica nanoparticles affect the adhesion properties. To address these questions, synthesis and characterization of a series of uniform silica nanostructures with different sizes and shapes is carried out. Unexpectedly, none of the synthesized silica nanostructures without additional inorganic base shows adhesion properties against liver tissues. Such surprising phenomena motivate to examine other factors in the commercial silica nanoparticles as tissue adhesives, and reach a conclusion that the inorganic base plays a key role in the adhesion properties. It is believed that this study answers the important question whether silica nanoparticles can act as biological adhesives or not. The conclusion also gives a lesson to other scientists and engineers in design and exploration of new biological adhesives.
Using Local Health Information To Promote Public Health (2006)

Local health information can be a powerful vehicle for improving the health of a community. It can highlight both the existence of problems and opportunities for improvement. It can also guide local action in support of policy changes and improve programs' effectiveness. However, efforts to expand the availability and use of local health information face major technical and institutional barriers, as well as health information privacy concerns. This paper provides an overview of current issues surrounding the availability and use of local health information, identifies barriers that hinder its use, and suggests potential solutions.
Sieve Email Filtering: Reject and Extended Reject Extensions (2009)

This memo updates the definition of the Sieve mail filtering language
(RFC draft-ietf-sieve-3028bis-XX.txt) reject extension, originally
defined in RFC 3028. A is a spam run forged to appear as
though it came from an innocent party, who is then generally flooded
by automated bounces, Message Disposition Notifications (MDNs), and
personal messages with complaints. The original Sieve reject action
defined in RFC 3028 required use of MDNs for rejecting messages, thus
contributing to the flood of Joe-job spam to victims of Joe-jobs.
This memo updates the definition of the reject action to allow
messages to be refused during the SMTP transaction, and defines the
ereject action to require messages to be refused during the SMTP
transaction. The ereject action is intended to replace the reject
action wherever possible.
Determining Water Content in Human Nails with a Portable Near-Infrared Spectrometer (2003)

The water content of human nail plates was determined using a portable near-infrared (NIR) spectrometer with an InGaAs photodiode array detector. NIR diffuse reflectance (DR) spectra were collected from 108 cut nail plates with different relative humidity and in vivo from fingernails. Partial least-squares (PLS) regression was applied to the NIR spectra in the 1115-1645 nm region to develop calibration models that determine the water content in the cut nail plates and fingernails. A good correlation was obtained between the NIR spectra and the water content measured by nuclear magnetic resonance (NMR) for the NIR measurement of both cut nail plates and fingernails. The results indicate that the water content in the nails can be determined very rapidly (1 s) by means of the portable NIR spectrometer and PLS regression.
Identification of cyclic peptides able to mimic the functional epitope of IgG1‐Fc for human FcyRI (2008)

Identification of short, structured peptides able to mimic potently protein-protein interfaces remains a challenge in drug discovery. We report here the use of a naive cyclic peptide phage display library to identify peptide ligands able to recognize and mimic IgG1-Fc functions with Fc gammaRI. Selection by competing off binders to Fc gammaRI with IgG1 allowed the isolation of a family of peptides sharing the common consensus sequence TX(2)CXXthetaPXLLGCPhiXE (theta represents a hydrophobic residue, Phi is usually an acidic residue, and X is any residue) and able to inhibit IgG1 binding to Fc gammaRI. In soluble form, these peptides antagonize superoxide generation mediated by IgG1. In complexed form, they trigger phagocytosis and a superoxide burst. Unlike IgG, these peptides are strictly Fc gammaRI-specific among the Fc gammaRs. Molecular modeling studies suggest that these peptides can adopt 2 distinct and complementary conformers, each able to mimic the discontinuous interface contacts constituted by the Cgamma2-A and -B chains of Fc for Fc gammaRI. In addition, by covalent homodimerization, we engineered a synthetic bivalent 37-mer peptide that retains the ability to trigger effector functions. We demonstrate here that it is feasible to maintain IgG-Fc function within a small structured peptide. These peptides represent a new format for modulation of effector functions.
Electromechanical Modeling of Micro Electret Generator for Energy Harvesting (2007)

A numerical model for in-plane electret power generators has been developed. Through detailed comparison, we have confirmed that the response of the present model is in good agreement with our experimental power generation data. Electrostatic force both in the horizontal and vertical directions is examined with the model computation. We also propose an electrode arrangement for reducing the in-plane unidirectional damping force. With this arrangement, the damping force of the electret generator becomes similar with that of the velocity-damped resonant generator.
Theory of concentric designs for grating spectrometers (1994)

A concentric optical design for a grating spectrometer is described. General aberration theory is given for a family of designs of similar form, showing close similarities with the theory for conventional concentric imagers used in microlithography. Control of stray radiation in the concentric grating spectrometer is discussed.
Rapid Detection of Enteroviruses in Small Volumes of Natural Waters by Real-Time Quantitative Reverse Transcriptase PCR (2005)

Despite viral contamination of recreational waters, only bacterial, not viral, indicators are monitored routinely, due to a lack of rapid and cost-effective assays. We used negatively charged filters to capture enteroviruses from seawater and freshwater. Viral RNA was extracted using a commercial kit, and the viruses were quantified by real-time quantitative reverse transcriptase PCR (qRT-PCR). Poliovirus (6.6 to 330,000 virus particles/ml) was added to samples from watersheds in Los Angeles, California, and analysis showed that with 50-ml samples, a cellulose acetate/nitrate (HA) filter yielded final recovery of 51% (r2= 0.99) in fresh water and 23% (r2= 0.90) in seawater. However, for additions of low levels of virus (more likely to represent field samples; <10(4) enterovirus particles/ml), the recovery was lower and more variable, with HA being best in freshwater (17%, r2= 0.97) and the type GF/F glass filter having higher average recovery in seawater (GF/F, 17%; r2= 0.93; HA 12%, r2= 0.87). The optimized method was used with 1-liter field samples from two very different freshwater "creeks" that drain into Santa Monica Bay, California: Topanga Creek (TC), a relatively pristine mountain creek, and Ballona Creek (BC), a concrete-lined urban storm drain. One TC site out of 10 and 2 BC sites out of 7 tested significantly positive for enteroviruses, with higher enterovirus concentrations in BC than in TC (ca. 10 to 25 versus 1 equivalent enterovirus particle/ml). The presented filtration-qRT-PCR approach is fast (<8 h from sampling to results), sensitive, and cost efficient and is promising for monitoring viral contamination in environmental water samples.
Insight into the Fluid-Phase Miscibility of Ester and Ether Phospholipids through Analysis of Nearest-Neighbor Recognition <i>J</i>. <i>Am</i>. <i>Chem</i>. <i>Soc</i>. <b>1996</b>, <i>118</i>, 7069−7074 (1996)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTInsight into the Fluid-Phase Miscibility of Ester and Ether Phospholipids through Analysis of Nearest-Neighbor Recognition J. Am. Chem. Soc. 1996, 118, 7069−7074Takehisa Dewa and Steven L. RegenCite this: J. Am. Chem. Soc. 1996, 118, 37, 8985–8986Publication Date (Web):September 18, 1996Publication History Published online18 September 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/ja965420whttps://doi.org/10.1021/ja965420wcorrectionACS PublicationsCopyright © 1996 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views258Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (54 KB) Get e-Alertsclose Get e-Alerts
Polarization QAM Modulation (POL-QAM) for Coherent Detection Schemes (2009)

A new polarization constellation diagram leads to polarization QAM modulation formats. At 28Gbaud (112Gb/s) POL-QAM 6-4 with six QPSK modulated states-of-polarization enables 1.7-dB higher sensitivity than PDM-QPSK by applying coded-modulation with an inner RS(511,455) FEC.
<title>Blood pressure, pulse rate, and rhythm measurement using ionic polymer-metal composite sensors</title> (1999)

The need for more enhanced blood pressure (BP), pulse rate and rhythm senors has given rise to the possibility of using ionic polymer-metal composites (IPMCs) sensors. In this study we propose to use the IPMC sensors to measure systolic and diastolic BP, pulse rate and rhythm. The proposed IPMC sensors take advantage of the endo-ionic mobility within the polymer- metal composite by converting normal and shear load inputs into an induced voltage output across the thickness of the IPMC sensor. The fabricated IPMC sensors are suitable to be installed on the inner surface of a cuff and, therefore, both systolic and diastolic BP, pulse rate, and rhythm can be measured. An added benefit is the ability of measuring 'pulse rhythm' which give a more amplified look at heart irregularities which a typical pulse rate sensor is unable to show. Our data shows IPMC sensors can produce consistent and reliable BP readings, pulse rate, and rhythm. Typically, a linear relationship between applied maximum load and induced maximum voltage was obtained. This result can be easily translated into good BP reading.
Self-Induced Preparation of Assembled Shrubbery TiSi Nanowires by Chemical Vapor Deposition (2008)

We report a new self-induced catalyst-free method for the preparation of shrubbery TiSi nanowires by atmospheric pressure chemical vapor deposition. SiH4 and TiCl4 are used as a silicon precursor and titanium precursor, respectively. Ti5Si3 thin films are formed initially, and then one-dimensional TiSi nanostructures are grown on top of the thin films. A novel, assembled structure with electrically conductive shrubbery TiSi nanowires with an electrically conductive Ti5Si3 thin layer underneath is finally obtained. The TiSi nanowires grow along the direction perpendicular to the (110) plane of the orthorhombic TiSi crystal. The nanowires are more than 5 μm long, and their diameters are about 15−40 nm. With the flux of (SiH4 + TiCl4) reaching values larger than 35 sccm or increasing from 20 to 35 sccm, the quantities of TiSi nuclei are increased and, thus, the TiSi nanowire bundles and rocket-shaped nanowires are also successfully prepared, respectively. With regard to producing a high storage capacitor with the nanowire bottom electrode embedded within the dielectric thin film of Ba0.6Sr0.4TiO3 (BST), the capacitance of the BST/assembled-nanowire-electrode complex structure is about 28 pF, which is approximately 3 times higher than that of BST deposited on indium-tin oxide (ITO). This creates a new way to fabricate the thin film devices with a high storage capacitance.
Nicolas LEBLOND, Assurances et sûretés (2010)

International audience
Treatment of mammalian spinal cord injury with antioxidants (1991)

After spinal cord injury, two groups of cats were treated with a combination of methylprednisolone sodium succinate (MP, 35 mg/kg) and epsilon-aminocaproic acid (EACA, 350 mg/kg), and guanabenz acetate (0.65 mg/kg). Guanabenz acetate was administered twice daily for 8 weeks. In the first group, the treatment significantly increased blood flow in the abdominal aorta. All cats treated with guanabenz acetate 3 hr after spinal cord contusion had return of micturition and none suffered complete paraplegia. Four animals had partial and the other four had complete motor recovery. A superoxide (O2-.) generating system, horseradish peroxidase, decreased [14C]gamma amino butyric acid uptake by mouse cortical slices by 33% but when superoxide dismutase was added to the medium, the uptake was reduced by only 9%. The nerve endings were also protected by superoxide dismutase from morphologic damage by O2-. as observed by electron microscopy. The agents used in these studies produce their ameliorating effects by virtue of their anti-inflammatory, antioxidant, and membrane stabilizing properties, and enhancing the regional microcirculation. In addition to having these properties, guanabenz acetate is also an alpha 2 adrenoceptor agonist.