gebhart/patrepeval huggingface dataset:
Ion Mobility Mass Spectrometry of Peptide Ions: Effects of Drift Gas and Calibration Strategies (2012)

One difficulty in using ion mobility (IM) mass spectrometry (MS) to improve the specificity of peptide ion assignments is that IM separations are performed using a range of pressures, gas compositions, temperatures, and modes of separation, which makes it challenging to rapidly extract accurate shape parameters. We report collision cross section values (Ω) in both He and N(2) gases for 113 peptide ions determined directly from drift times measured in a low-pressure, ambient temperature drift cell with radio-frequency (rf) ion confinement. These peptide ions have masses ranging from 231 to 2969 Da, Ω(He) of 89-616 Å(2), and Ω(N(2)) of 151-801 Å(2); thus, they are ideal for calibrating results from proteomics experiments. These results were used to quantify the errors associated with traveling-wave Ω measurements of peptide ions and the errors concomitant with using drift times measured in N(2) gas to estimate Ω(He). More broadly, these results enable the rapid and accurate determination of calibrated Ω for peptide ions, which could be used as an additional parameter to increase the specificity of assignments in proteomics experiments.
The major histocompatibility complex-restricted response of recombinant inbred strains of mice to natural tick transmission of Borrelia burgdorferi. (1993)

The causative agent of Lyme disease, Borrelia burgdorferi, is transmitted by ticks of the Ixodes ricinus complex. In this study, we report the antibody response of recombinant inbred strains of mice of the H-2, b, d, and k haplotypes, infected with B. burgdorferi as a result of exposure to infected I. dammini. The patterns of antibody response assayed by Western blot analysis indicate significant major histocompatibility complex (MHC) restriction to bacterial antigens within the first 2 mo of infection in mice. Other bacterial antigens induce a significant response across the MHC haplotypes tested when assayed on the same bacterial strain used to transmit the infection, but do not crossreact with the same proteins derived from heterologous strains of B. burgdorferi. No response to outer surface protein A was detected at any time during the 60-d period we analyzed this infection. A third group of bacterial antigens appear to generate a MHC-nonrestricted response, and this lack of restriction is maintained when assaying the crossreactivity of the response with other strains of B. burgdorferi. These proteins may provide more accurate diagnostic probes than those currently in use. Finally, there appears to be a significant difference in the expression of most bacterial antigens when the spirochete is cultured for many passages since the same strain of bacterium isolated from low-passage and high-passage preparations exhibit different banding patterns in Western blots when assayed with the same sera.
[Indocyanine green video angiographic findings of frosted branch angitis in a child]. (1998)

A 10-year-old boy presented with typical fundus findings of frosted branch angitis in both eyes. Fluorescein angiography showed late-phase hyperfluorescence in some active areas of vascular lesions. Indo-cyanine green (ICG) angiography showed similar but less extensive hyperfluorescence along the frosted vessels and in the disc. ICG angiography also showed filling delay in the choriocapillaris. These findings suggest that frosted branch angitis is a manifestation of inflammation in the retina and the choroid. Laboratory studies showed increase in the toxoplasma titer at 1:10,240 and in the serum levels of alpha 1 and alpha 2 globulin. Frosted branch angitis in this case seemed to be the consequence of local allergic reaction, or immune complex deposition, presumably due to toxoplasma infections.
Analysis of Coaxial Ridged Disk-Loaded Slow-Wave Structures for Relativistic Traveling Wave Tubes (2004)

The coaxial ridged disk-loaded structure which is a new disk-loaded periodic system is presented and analyzed in this paper. As an all-metal slow-wave circuit, it has properties that can be used in high-power traveling wave tubes (TWT) and relativistic TWTs. The dispersion equation and coupling impedance of the structure are investigated in the first part of this paper. The results of numerical calculations of the dispersion relation and coupling impedance with different structure dimensions indicate that the interaction impedance of the ridged disk-loaded structure is higher than that of the disk-loaded structure without ridges in most frequency ranges. In the second part, the "hot" dispersion equation of this circuit with an annular electron beam is obtained according to a self-consistent linear theory. The influence of physical dimensions and beam parameters on the small signal gain is discussed.
Diagnosis of body online detecting dimensional deviation based on pattern recognition (2011)

The application of online detection of auto-body has become increasingly a popular trend;However,how to effectively use measurement data of online detection by 100% is a problem.The traditional diagnostic methods of dimensional deviation depend on the presence of engineering experience to judge,which leads to time consumption and low accuracy.An approach combining the time series pattern recognition and Principal Component Analysis(PCA)is applied to diagnose auto-body dimensional deviation,realize pattern recognition of the error source and automatic alarm diagnosis.Meanwhile the appropriate tools are developed and verified successfully in the actual production of car body.
0.07 mm <sup>2</sup> , 2 mW, 75 MHz-IF, fourth-order BPF using source-follower-based resonator in 90 nm CMOS (2012)

A highly-transistorised bandpass filter (BPF) using a source-follower-based (SFB) resonator is proposed. It benefits from the advantageous properties of the source follower (e.g. no parasitic pole, linear VGS I/O relationship, high-input and low-output impedances), while combining it with a compact and low-power grounded differential active inductor to synthesise the complex poles. Fabricated in 90 nm CMOS, a fourth-order 75 MHz-IF BPF prototype merging two such SFB resonators measures a 10 MHz bandwidth at 2 mW of power. The die size is merely 0.07 mm2.
Streaking images that appear only in the plane of diffraction in undoped GaAs single crystals: Diffraction imaging (topography) by monochromatic synchrotron radiation (1988)

Streaking images restricted to the direction of the diffraction (scattering) vector have been observed on transmission through undoped GaAs. These disruption images (caused by the reduction of diffraction in the direction of observation) appear both in the forward and Bragg-diffracted directions in monochromatic-synchrotron-radiation diffraction imaging. This previously unobserved phenomenon can be explained in terms of planar defects (interfaces) or platelets which affect the absorption coefficient in anomalous transmission. Such regions of the crystal look perfect despite the presence of imperfections when the scattering vector is not perpendicular to the normal of the platelets. The observed crystallographic orientation of these interfaces strongly indicates that they are antiphase boundaries.
Glomerular Epithelium: Structural Alterations Induced by Polycations (1975)

Perfusion of rat kidneys with the polycation protamine sulfate caused glomerular epithelial alterations resembling those observed in human and experimental nephrotic states. The changes included swelling, blunting, and flattening of epithelial foot processes, were accompanied by decreased stainability of glomerular anionic sites, and were largely reversed by subsequent perfusion with the polyanion heparin.
Agrobacterium tumefaciens mutants affected in attachment to plant cells (1982)

An analysis of Agrobacterium tumefaciens mutants with Tn5 insertions in chromosomal DNA showed that the chromosome of A. tumefaciens codes for a specific ability of this bacterium to attach to plant cells. This ability is associated with tumorigenesis by A. tumefaciens, the ability of avirulent A. tumefaciens to inhibit tumorigenesis, and the ability to adsorb certain phages. A second class of chromosomal mutations affects tumorigenesis without altering the ability to attach to plant cells. The attachment of A. tumefaciens to plant cells was assayed by mixing radiolabeled bacteria with suspensions of tobacco tissue culture cells or freshly isolated Zinnia leaf mesophyll cells. Under the conditions of this assay, an avirulent Ti plasmid-cured strain attached to the same extent as the same strain containing pTiB6806. Six of eight avirulent mutants with Tn5 insertions in chromosomal DNA showed defective attachment, whereas two retained wild-type attachment ability. In contrast to the strains showing wild-type attachment, the attachment-defective mutants failed to inhibit tumorigenesis when inoculated onto Jerusalem artichoke slices before inoculation of a virulent strain and also showed a loss of sensitivity to two Agrobacterium phages. The loss of phage sensitivity appeared to be due to a loss of ability to adsorb the phages. Staining with Calcofluor indicated that the mutants retained the ability to synthesize cellulose fibrils, which have been implicated in the attachment process. Southern filter hybridizations demonstrated that each mutant contained a single Tn5 insertion, and genetic linkage between the Tn5 insertion in one mutant and the attachment phenotype has also been demonstrated.
Excellent resistance switching characteristics of Pt/SrTiO/sub 3/ schottky junction for multi-bit nonvolatile memory application (2006)

We have investigated single crystal Nb-doped SrTiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> in terms of its potential utility in nonvolatile memory applications. Compared with polycrystalline oxide (Nb <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sub> , ZrO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> and Cr-SrTiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> ), the Pt/single crystal Nb:SrTiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> Schottky junction exhibits excellent memory characteristics including uniformity of set/reset bias, die-to-die reproducibility, data retention at high temperature, reliability under cycle stress, and multi-bit operation characteristics. The switching mechanism might be explained by modulation of the Schottky barrier height by charge trapping at the interface
Normal Human Keratinocytes Bind to the α3LG4/5 Domain of Unprocessed Laminin-5 through the Receptor Syndecan-1 (2003)

Basal keratinocytes of the epidermis adhere to their underlying basement membrane through a specific interaction with laminin-5, which is composed by the association of alpha3, beta3, and gamma2 chains. Laminin-5 has the ability to induce either stable cell adhesion or migration depending on specific processing of different parts of the molecule. One event results in the cleavage of the carboxyl-terminal globular domains 4 and 5 (LG4/5) of the alpha3 chain. In this study, we recombinantly expressed the human alpha3LG4/5 fragment in mammalian cells, and we show that this fragment induces adhesion of normal human keratinocytes and fibrosarcoma-derived HT1080 cells in a heparan- and chondroitin sulfate-dependent manner. Immunoprecipitation experiments with Na2 35SO4-labeled keratinocyte and HT1080 cell lysates as well as immunoblotting experiments revealed that the major proteoglycan receptor for the alpha3LG4/5 fragment is syndecan-1. Syndecan-4 from keratinocytes also bound to alpha3LG4/5. Furthermore we could show for the first time that unprocessed laminin-5 specifically binds syndecan-1, while processed laminin-5 does not. These results demonstrate that the LG4/5 modules within unprocessed laminin-5 permit its cell binding activity through heparan and chondroitin sulfate chains of syndecan-1 and reinforce previous data suggesting specific properties for the precursor molecule.
EDIF grows up (1990)

The Electronic Design Interchange Format (EDIF), now in its second revision and paving the way for universal data exchange among CAE tools, is examined. Translators can convert data files from a given design tool into EDIF as a standard format and from EDIF into the form needed by another design tool. The benefits of using EDIF for design capture tools, design analysis tools, and logic synthesizers are discussed. Examples of the successful use of EDIF are given, and some problems encountered in its use are considered. A table listing the features of representative software packages is given.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Hymenoptera Venom Allergy: Time Course of Specific IgE Concentrations during the First Weeks after a Sting (1999)

Detection of IgE antibodies specific to honeybee or Vespula venoms is an important criterium firstly for the diagnosis of sensitization and secondly for the indication for a specific immunotherapy. Some authors recommend to postpone blood analysis after an insect sting for a certain time because circulating IgE antibodies might be consumed by the allergic reaction, which would result in a false-negative test outcome. We investigated IgE concentrations during the first weeks after an insect sting in 31 patients with an unequivocal history of an anaphylactic reaction after a honeybee (n = 13) or Vespula (n = 18) sting. Blood samples for analysis of specific IgE concentrations (CAP system, Pharmacia Diagnostics, Sweden) were collected within 2 weeks and 5+/-2 weeks after the insect sting. 12/13 patients with honeybee venom and 14/18 patients with Vespula venom sensitization had CAP classes 1 or higher within the first 2 weeks. Those 5 patients with CAP class 0 within the first 2 weeks had detectable IgE concentrations a few weeks later. We conclude that testing for specific IgE to hymenoptera venoms is in most cases useful even during the first 2 weeks after the hymenoptera sting. This allows early decisions on further diagnostic procedures and the therapeutic way to choose. Patients with no detectable IgE should, however, be retested after a few weeks.
Multivariable Feedback Design (1989)

Provides a comprehensive and unified view of modern multivariate feedback theory and design. Balancing techniques with theory, the objective throughout is to enable the feedback engineer to design real systems.
A Synchronization Control Scheme for Videoconferencing Services (2007)

We propose a synchronization control scheme which achieves both speech/video Intra-Stream synchronizations and Inter-Stream synchronization for videoconferencing services over IP networks. The driving principle of our scheme is to guarantee the Intra-Sync speech timing relationships (hence the speech quality) and to adjust the video Intra-Sync and the Inter-Sync accordingly. Towards this aim we use a preventive control for the speech stream and a reactive control for the video stream. More precisely, we use an adaptive playout algorithm that keeps the Intra- Sync constraints within the talkspurts, while the network jitters are compensated by modifying only the silence period lengths on the basis of both speech and video packet delays. We implemented our scheme in a prototype, which allowed us to test the effectiveness of our solution. Actually, we could appreciate both perfect speech intelligibility and very satisfactory user perceived lip-sync. The latter is because the Inter-Sync error is concentrated only at the beginning of the talkspurts, where known experimental tests have shown that it is not detectable.
Latency-driven distribution: infrastructure needs of participatory entertainment applications (2005)

This article evaluates network and server infrastructure requirements to support real-time flows associated with networked entertainment applications. These include the state information flow to update the status of the virtual environment and immersive communication flows such as voice, video, gesture, and haptics communication. The article demonstrates that scaling these applications to large geographical spreads of participants requires distribution of computation to meet the latency constraints of the applications. This latency-driven distribution of computation is essential even when there are no limitations on the availability of computational resources in one location. The article provides detailed results on distributed server architectures for two of these real-time flows, state information and immersive voice communication. It also identifies a generic set of requirements for the underlying network and server infrastructure to support these applications and propose a new design, called switched overlay networks, for this purpose.
Comparison of two types of intravenous immunoglobulins in the treatment of neonatal sepsis (1995)

SUMMARY In a prospective double-blind study, standard intravenous immunoglobulin (IVIG) was compared with an IgM-enriched IVIG in the treatment of neonatal sepsis. The two treatment groups were also compared with matched controls. One hundred and thirty babies (65 in each group) ranging from 0 to 24 days old, 480 to 4200 g in weight and born between 24 and 42 weeks of gestation who had, or were suspected of having, sepsis were given either standard IVIG or IgM-enriched IVIG (250 mg/kg per day) for 4 days in addition to supportive and antibiotic therapy. A further 65 babies who received similar supportive, antibiotic and fluids but not IVIG were used as matched controls. Mortality from infection in ‘culture proven sepsis’ was 3/44 (6·8%) in the IgM-enriched IVIG group, 6/42 (14·2%) in the standard IVIG group, and 11/43 (25·5%) in the control group (P = 0·017, IgM versus control, P = 019 standard IVIG versus control). There was no statistical difference in the outcome between the two immunoglobulin therapy groups (P = 0·25). The study indicates that IVIG improves outcome in neonatal sepsis when used as an adjunct to supportive and antibiotic therapy, but larger studies are required to confirm this.
Cyclic Aminoacyloins. III. Synthesis, Properties and the Detection of Transannular Interaction between N and C<sub>CO</sub><sup>1,2</sup> (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCyclic Aminoacyloins. III. Synthesis, Properties and the Detection of Transannular Interaction between N and CCO1,2Nelson J. Leonard, Richard C. Fox, and Michinori OkiCite this: J. Am. Chem. Soc. 1954, 76, 22, 5708–5714Publication Date (Print):November 1, 1954Publication History Published online1 May 2002Published inissue 1 November 1954https://pubs.acs.org/doi/10.1021/ja01651a031https://doi.org/10.1021/ja01651a031research-articleACS PublicationsRequest reuse permissionsArticle Views322Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
In vivo ligation of linear DNA molecules to circular forms in the yeast Saccharomyces cerevisiae (1983)

The yeast Saccharomyces cerevisiae was transformed with restriction endonuclease-digested (linear) DNAs containing the replication origin of the yeast 2 microns plasmid and selectable markers with efficiencies of 10(3) to 10(4), 10(3), and 10(2) to 10(3) transformants per microgram of DNA in the cases of transformations with linear DNAs containing the same cohesive ends, flush ends, and non-complementary cohesive ends, respectively. The results of a restriction analysis of the circular plasmids recovered from transformed cells suggested that the linear DNA molecules were ligated to produce circular forms in the recipient protoplasts.
Nanostructured Materials Development for Space Power (2003)

There have been many recent advances in the use of nanostructured materials for space power applications. In particular, the use of high purity single wall nanotubes holds promise for a variety of generation and storage devices including: thin film lithium ion batteries, microelectronic proton exchange membrane (PEM) fuel cells, polymeric thin film solar cells, and thermionic power supplies is presented. Semiconducting quantum dots alone and in conjunction with carbon nanotubes are also being investigated for possible use in high efficiency photovoltaic solar cells. This paper will review some of the work being done at RIT in conjunction with the NASA Glenn Research Center to utilize nanomaterials in space power devices.
High Frequency Band Acoustic Positioning Equipment - Its Evolution and Integration with Other Systems (1987)

The requirement for survey quality subsea measurements originated in the offshore construction industry. Advances in research sensor and processing technology have extended this need to numerous other scientific disciplines. This paper describes the characteristics of Oceano's 54-108 kHz acoustic ranging hardware and its evolution. System configurations are described for integrated long and short baseline modes plus variable secondary baseline techniques. Data is included which demonstrates range accuracy, noise immunity and computed position results. A developmental system is also introduced which combines geodetic/acoustic navigation with a complete multi-sensor, multi-task acquisition software. This software offers a convenient analysis format which can manipulate the data on an integrated basis.
Non-small-cell lung cancer: results of the New York screening program. (1984)

Radiographs of 168 patients with non-small-cell lung cancer were reviewed. Following a negative initial examination, 102 tumors were detected during routine annual screening, while 66 were diagnosed during the interval between screenings. The cancers detected on routine yearly examination were smaller; the rate of resectability was higher, a larger number were Stage I, and survival was better. Within the routinely screened group, 65% had evidence of cancer on reviewing earlier radiographs; these patients tended to have earlier stages of cancer and a better survival rate.