gebhart/patrepeval huggingface dataset:
PERFIL DERMATOGLÍFICO E DETERMINAÇÃO DA FREQUÊNCIA GENOTÍPICA DA ACTN3 EM ATLETAS PROMESSAS OLÍMPICAS (2013)

A analise de diversos fatores geneticos tem sido utilizada como uma abordagem relativamente nova para a compreensao do rendimento esportivo. Esses novos caminhos oferecem a utilizacao etica das biotecnologias para a ampliacao das possibilidades na orientacao esportiva adequada; assim, quanto maior a busca para prescricoes corretas, melhores os resultados. Desse modo, objetivou-se identificar o perfil dermatoglifico e a manifestacao do polimorfismo do gene ACTN3 em atletas promessas olimpicas. O protocolo escolhido para analisar o potencial genetico por meio da coleta das impressoes digitais foi o Dermatoglifico, proposto por Cummins e Midlo (1961), por intermedio do Leitor Dermatoglifico, validado por Nodari Junior (2009). Os individuos foram genotipados para o polimorfismo da α-actinina-3 e divididos em grupos de mesmo genotipo RR, RX e XX, por meio das tecnicas de Reacao em Cadeia de Polimerase (PCR) e Polimorfismo do Comprimento de Fragmentos de Restricao (RFLP) com enzima de restricao (DdeI) apos a extracao do DNA. A amostra do estudo foi formada por 91 atletas, de ambos os sexos, com media de idade de 16,36 ± 3,68 anos, das modalidades de basquete, boxe, futebol, ginastica artistica, luta olimpica e voleibol de um centro de excelencia esportivo. A distribuicao dos genotipos da ACTN3 foi de 43,96% para o genotipo RX, 30,77% para o XX e 25,27% para o RR. Para a dermatoglifia, o valor medio encontrado para o somatorio da quantidade total de linhas (SQTL) foi de 113 ± 38,37, para a figura arco (A) a media foi de 0,4 ± 1,33, para a presilha radial (LR) de 0,4 ± 0,64, a presilha ulnar (LU) de 6,0 ± 2,78, o verticilo (W) de 3,2 ± 2,97 e o Indice de Delta (D10) apresentou a media de 12,8 ± 3,59. O aumento do genotipo XX pode estar relacionado a heterogeneidade do grupo, selecao positiva do alelo X na populacao, como tambem a um maior envolvimento em atividades de resistencia. Por meio dos recursos disponiveis nao foi possivel realizar uma analise estatistica que conseguisse identificar se existe relacao ou nao entre o gene ACTN3 e a dermatoglifia. Torna-se necessaria a aplicacao de uma estatistica mais robusta das variaveis investigadas, por meio de ferramentas mais adequadas, que permitam a analise mais complexa dos dados apresentados. Sugere-se, ainda, a realizacao de novos estudos que incluam uma amostra mais significativa e um grupo-controle, formado por individuos nao atletas, para que os resultados sejam ainda mais qualificados. Palavras-chave: Atletas. Dermatoglifia. Gene.
A Scaffold Protein JIP-1b Enhances Amyloid Precursor Protein Phosphorylation by JNK and Its Association with Kinesin Light Chain 1 (2003)

Amyloid precursor protein (APP) is the precursor molecule of beta-amyloid peptides, the major components of amyloid plaque in patients with Alzheimer's disease. In this study, we isolated JIP-1b, a JNK signaling scaffold protein, as a binding protein of APP, and analyzed the roles of JIP-1b in APP phosphorylation by JNK and the association of kinesin light chain 1 with APP. APP phosphorylation at threonine 668 by JNK was enhanced on the JIP-1b scaffold in vitro and in cultured cells exogenously expressing APP. APP phosphorylation in nerve growth factor-differentiated PC12 cells was mediated by activation of JNK signaling. JIP-1b also enhanced the association of kinesin light chain 1 with APP. Our results suggest that JIP-1b may function as a protein linking the kinesin-I motor protein to the cargo receptor, APP, and that the JNK signaling pathway may regulate the phosphorylation of this cargo protein through the JIP-1b scaffold.
Expression of Nitric Oxide Synthase 2 and Tumor Necrosis Factor α in Swine Naturally Infected with <i>Actinobacillus pleuropneumoniae</i> (2002)

Nitric oxide synthase 2 (NOS2) and tumor necrosis factor alpha (TNF-alpha) were detected and localized in 15 pigs with naturally occurring pleuropneumonia by use of in situ hybridization with a nonradioactive digoxigenin-labeled cDNA probe. Two cDNA probes 491 and 219 base pairs for NOS2 and TNF-alpha, respectively, were generated by reverse transcription polymerase chain reaction. All 15 pigs infected with Actinobacillus pleuropneumoniae had distinct positive hybridization signals for NOS2 and TNF-alpha. Strong hybridization signals for both NOS2 and TNF-alpha were evident in degenerate alveolar leukocytes bordering zones of coagulative necrosis and in alveolar spaces. NOS2 nucleic acids were detected in neutrophils and macrophages. In situ hybridization of serial sections of lung tissue revealed numerous cells positive for NOS2 and TNF-alpha, suggesting that NOS2 and TNF-alpha expression may play a role in the pathophysiology of pleuropneumonia.
Formation of MSeO<sub><scp>4</scp></sub>(aq) complexes (M<sup><scp>2</scp>+</sup> = Mg<sup><scp>2</scp>+</sup>, Co<sup><scp>2</scp>+</sup>, Ni<sup><scp>2</scp>+</sup>, Cu<sup><scp>2</scp>+</sup>, Cd<sup><scp>2</scp>+</sup>) studied as a function of temperature by affinity capillary electrophoresis (2012)

Complexation of divalent cations (Mg(2+), Co(2+), Ni(2+), Cu(2+), Cd(2+)) by selenate ligand was studied by ACE (UV indirect detection) in 0.1 mol/L NaNO(3) ionic strength solutions at various temperatures (15, 25, 35, 45 and 55°C). For each solution, a unique peak was observed as a result of a fast equilibrium between the free ion and the complex (labile systems). The migration time corresponding to this peak changed as a function of the solution composition, namely the free and complexed metal concentrations, according to the complexation reactions. The results confirmed the formation of a unique 1:1 complex for each cation. The thermodynamic parameters were fitted to the experimental data at 0.1 mol/L ionic strength: (25°C) = -(6.5 ± 0.3), -(7.5 ± 0.3), -(7.7 ± 0.3), -(7.7 ± 0.3), and -(8.1 ± 0.3) kJ/mol and = 2.5 ± 0.2, 4.7 ± 0.4, 4.5 ± 0.6, 8.4 ± 1.1, and 7.2 ± 0.6 kJ/mol for M(2+) = Mg(2+), Co(2+), Ni(2+), Cu(2+), and Cd(2+), respectively. Complexes with alkaline earth and transition metal cations could be distinguished by their relative stabilities. The effect of the ionic medium was treated using the specific ion interaction theory and the thermodynamic parameters at infinite dilution were compared to previously published data on metal-selenate, metal-sulfate, and metal-chromate complexes.
Analysis of grating light valves with partial surface electrodes (1998)

The grating light valve (GLV) is a micro-electromechanical reflection phase grating that operates on the electrostatic deflection of microbeams. In a conventional GLV, each beam is coated with a surface electrode that spans its length. In this paper, a GLV with partial electrode coverage is studied. An analysis is presented of the deflection profile and switching voltage for a series of electrode lengths. These results are compared with the performance of a conventional GLV.
Isolation of a Novel Family of C2H2 Zinc Finger Proteins Implicated in Transcriptional Repression Mediated by Chicken Ovalbumin Upstream Promoter Transcription Factor (COUP-TF) Orphan Nuclear Receptors (2000)

Two novel and related C(2)H(2) zinc finger proteins that are highly expressed in the brain, CTIP1 and CTIP2 (COUP TF-interacting proteins 1 and 2, respectively), were isolated and shown to interact with all members of the chicken ovalbumin upstream promoter transcription factor (COUP-TF) subfamily of orphan nuclear receptors. The interaction of CTIP1 with ARP1 was studied in detail, and CTIP1 was found to harbor two independent ARP1 interaction domains, ID1 and ID2, whereas the putative AF-2 of ARP1 was required for interaction with CTIP1. CTIP1, which exhibited a punctate staining pattern within the nucleus of transfected cells, recruited cotransfected ARP1 to these foci and potentiated ARP1-mediated transcriptional repression of a reporter construct. However, transcriptional repression mediated by ARP1 acting through CTIP1 did not appear to involve recruitment of a trichostatin A-sensitive histone deacetylase(s) to the template, suggesting that this repression pathway may be distinct from that utilized by several other nuclear receptors.
A 10-bit, 20-MS/s, 35-mW pipeline A/D converter (2002)

This paper describes a 10-bit 20-MS/s pipeline A/D converter implemented in 1.2-/spl mu/m CMOS technology which achieves a power dissipation of 35 mW at full speed operation. Circuit techniques used to achieve this level of power dissipation include operation on a 3.3 V power supply, optimum scaling of capacitor values through the pipeline, and digital correction to allow the use of dynamic comparators. Measured performance includes 0.6 LSB of INL, 59.1 dB of SNDR for 100 kHz input at 20 MS/s. At Nyquist sampling (10 MHz input), SNDR is 55.0 dB.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Resonantly enhanced selective photochemical etching of GaN (2009)

Wavelength dependent photochemical etching of GaN films reveals a strong resonant enhancement of the photocurrent at the GaN gap, in close agreement with the excitonic absorption profile of GaN. The corresponding etching rate of GaN strongly correlates with the measured photocurrent. No photocurrent, nor etching is observed for AlGaN films under same excitation conditions. The method could pave the way to the development of truly selective etching of GaN on AlGaN for the fabrication of nitride based optoelectronic devices.
An Optimal Filter for Geostrophic Mesoscale Currents from Along-Track Satellite Altimetry (2004)

An optimal difference operator is derived for smoothing along-track sea surface height measurements from satellite altimeters and computing geostrophic surface currents at or below ocean mesoscale wavelengths with second-order approximation accuracy. The difference operator minimizes the white noise of the height measurements to find a compact difference formula for the sea surface height derivative and a residual noise estimate for the surface geostrophic velocity. This compact, optimal operator has fine along-track spatial resolution ideal for studies in areas of shallow water, near landfall, and at high latitudes where the first-baroclinic Rossby radius of deformation becomes small. Accurate extraequatorial geostrophic velocities are determined by varying the filter window to maintain accuracy and resolution, which will benefit global mesoscale studies from the tandem Jason-1 and TOPEX/Poseidon missions and, particularly, the proposed wide-swath altimetry mission.
STRATIGRAPHIC FRAMEWORK OF THE BARROW GROUP AND IMPLICATIONS FOR THE HYDROCARBON POTENTIAL OF THE WEST BARROW AREA (1992)

An integrated sequence stratigraphic approach has been used to resolve, with high resolution, the chronostratigraphy of the Barrow Group in the West Barrow area. Assessment of the hydrocarbon potential has resulted in identification of various play concepts and exploration risks. Five Barrow Group sequences are identified; each developed in response to tectonically or eustatically induced changes in sea level. The sequence stratigraphic framework provides an explanation for the distribution of reservoir and overpressure encountered in the area, and insight to the sealing potential within the Lower Barrow Group. Utilising the sequence analysis results, two strategies for geophysical mapping were established; structural mapping of reservoir/seal interfaces identified in Top Barrow and intra-Lower Barrow Group intervals, and secondly, amplitude mapping of seismic events associated with sandstones within the overpressured Lower Barrow Group. Amplitude extraction mapping of a seismic reflection generated by the submarine fan complex intersected by the West Barrow wells demonstrates a lobate areal geometry with well developed apparent channel axes. The occurrence of lobate sands within an overpressured shale, combined with hydrocarbon shows within the interval, highlight the stratigraphic potential in the area. Petrographic studies, however, indicate that diagenetic occlusion of pore space has downgraded the reservoir quality of these sands. At Top Barrow Group level, depth conversion of time structure maps using the midpoint depth technique has revealed structures not evident with time mapping. The largest closure encompasses the West Barrow-1A location where log analysis and gas homologue ratios indicate that a potential light oil/condensate hydrocarbon column may remain untested.
Comparison of ATP and in vivo bioluminescence for assessing the efficiency of immunomagnetic sorbents for live Escherichia coli O157:H7 cells (2002)

Bioluminescent assays provide an easy way to optimize conditions for the capture of bacteria by biosorbents in real time.
Relationship of fetal asphyxia to neuropathology and deficits in children. (1993)

Neuropathological studies suggest that the majority of the fetal asphyxial complications resulting in brain damage in either preterm or term fetus occur before the onset of labor. Anoxia because of the rapid sequence of events will usually result in death of the fetus. Hypoxia of 1-3 h duration may account for brain damage and deficits in children who survive. The threshold for brain damage is a severe acidosis with a pH < 7.0 in conjunction with systemic hypotension. The prevalence of antepartum fetal asphyxia and the frequency of deficits in such children have not been established. The prevalence of intrapartum fetal asphyxia determined biochemically is 2%. The majority of these children develop normally because of fetal cardiovascular compensatory mechanisms which protect the brain. However, beyond the threshold of asphyxia in either the preterm or term fetus, neuropathology may develop leading to deficits in some children.
Coordination for Multi-Robot Exploration and Mapping (2000)

This paper addresses the problem of exploration and mapping of an unknown environment by multiple robots. The mapping algorithm is an on-line approach to likelihood maximization that uses hill climbing to find maps that are maximally consistent with sensor data and odometry. The exploration algorithm explicitly coordinates the robots. It tries to maximize overall utility by minimizing the potential for overlap in information gain amongst the various robots. For both the exploration and mapping algorithms, most of the computations are distributed. The techniques have been tested extensively in real-world trials and simulations. The results demonstrate the performance improvements and robustness that accrue from our multirobot approach to exploration. 1
Acceleration of relational index structures based on statistics (2003)

Relational index structures, as for instance the Relational Interval Tree, the Relational RTree, or the Linear Quadtree, support efficient processing of queries on top of existing object-relational database systems. Furthermore, there exist effective and efficient models to estimate the selectivity and the I/O cost in order to guide the cost-based optimizer whether and how to include these index structures into the execution plan. By design, the models immediately fit to common extensible indexing/optimization frameworks, and their implementations exploit the built-in statistics facilities of the database server. In this paper, we show how these statistics can also be used for accelerating the access methods themselves by reducing the number of generated join partners. The different join partners are grouped together according to a cost-based grouping algorithm. Our first experiments on an Oracle9i database yield a speed-up of up to 1,000% for the Relational Interval Tree, the Relational R-Tree and for the Linear Quadtree.
Monodisperse Sprays for Various Purposes — Their production and characteristics (1996)

Abstract The production of liquid sprays represents a key technology for a wide range of industrial proceses. Most applications currently use pressure or air‐assisted atomization, resulting in the production of polydisperese sprays. Recent advances in experimental and numerical techniques for investigating liquid spraying processes, however, have enabled a closer examination of parameter optimization, leading to the conclusion that in may cases, a much narrower size distribution, or even a monodisperse spray, may exhibit many advantages. Currently monodisperse droplet generators, or drop‐on‐demand generators, do not meet this challenge of producing monodisperse sprays, primarily owing to the very low volume flow rate of liquid which is atomized. In the present work, a monodisperse sprya generator is introduced, which overcomes this difficulty for many applications.
Multichannel Landauer formula for thermoelectric transport with application to thermopower near the mobility edge (1986)

Various thermoelectric linear transport coefficients are defined and calculated for two reservoirs connected with ideal multichannel leads and a segment of an arbitrary disordered system. The reservoirs have different temperatures and chemical potentials. All of the inelastic scattering (and, thus, the dissipation) is assumed to occur only in the reservoirs. The definitions of the chemical potentials and temperature differences across the sample itself (mostly due to elastic scattering) are presented. Subtleties of the thermoelectric effects across the sample are discussed. The associated transport coefficients display deviations from the Onsager relations and from the Cutler-Mott formula for the thermopower (although the deviations vanish for a large number of channels and/or high resistance). The expression obtained is used to predict the critical behavior of the electronic thermopower near the mobility edge. It is shown to satisfy a scaling form in the temperature and separation from the mobility edge.
Polymerization of Substituted Styrenes by Atom Transfer Radical Polymerization (1997)

A series of substituted styrenes were polymerized by controlled/“living” radical polymerization using atom transfer radical polymerization (ATRP), in order to correlate monomer structures with polymerization rate. The effect of substituents is discussed with regard to the Hammett equation. The results show that most of the monomers can polymerize in a controlled way by ATRP; i.e., the apparent polymerization rate is first order with respect to monomer concentration, and molecular weight increases linearly with monomer conversion. The molecular weights obtained fit the theoretical values and polydispersities are relatively low (Mw/Mn < 1.5). Monomers with electron-withdrawing (EW) substituents result in better polymerization control and polymerize faster than those with electron-donating (ED) substituents. The apparent polymerization rate constants follow the Hammett equation with ρ = 1.5. Further study indicates that the difference of polymerization rates for different monomers can be attributed to both propagation constant, kp•, and the equilibrium constant, Keq, for atom transfer. Monomers with EW substituents have larger kp• and Keq values than those with ED substituents; therefore, EW substituents increase the monomer reactivity and decrease the stability of dormant species, while ED substituents have the opposite effects.
Full-time wearable headphone-type gaze detector (2006)

A headphone-type gaze detector for a full-time wearable interface is proposed. It uses a Kalman filter to analyze multiple channels of EOG signals measured at the locations of headphone cushions to estimate gaze direction. Evaluations show that the average estimation error is 4.4® (horizontal) and 8.3® (vertical), and that the drift is suppressed to the same level as in ordinary EOG. The method is especially robust against signal anomalies. Selecting a real object from among many surrounding ones is one possible application of this headphone gaze detector.
Polymeric phosphonium salts as a novel class of cationic biocides. VI. Antibacterial activity of fibers surface‐treated with phosphonium salts containing trimethoxysilane groups (1994)

Abstract Alkoxysilane with phosphonium biocides as coupling agents were covalently attached to cotton‐fiber surfaces, and the antibacterial activity of the surface‐treated fibers against Staphylococcus aureus and Escherichia coli was evaluated by the viable cell counting method in sterile distilled water. These fibers with phosphonium salts were found to exhibit high antibacterial activity against S. aureus and E. coli , particularly against S. aureus , and the activity increased as hydrophobicity of the substituents bonded directly to phosphonium ions increased. Furthermore, morphological changes of the cells of S. aureus and E. Coli in contact with the fibers were evaluated by scanning electron microscopy. It was found that the fiber with the phosphonium biocides exhibited bacteriostatic as well as bactericidal activity against both strains, which was evident from observation of normal and deformed cells of these species in contact with the fibers. © 1994 John Wiley & Sons, Inc.
EIA for Detection of Rochalimaea henselae-Reactive IgG, IgM, and IgA Antibodies in Patients with Suspected Cat-Scratch Disease (1993)

Journal Article EIA for Detection of Rochalimaea henselae-Reactive IgG, IgM, and IgA Antibodies in Patients with Suspected Cat-Scratch Disease Get access Noori E. Barka, Noori E. Barka Search for other works by this author on: Oxford Academic PubMed Google Scholar Ted Hadfield, Ted Hadfield Search for other works by this author on: Oxford Academic PubMed Google Scholar Madhumita Patnaik, Madhumita Patnaik Search for other works by this author on: Oxford Academic PubMed Google Scholar William A. Schwartzman, William A. Schwartzman Search for other works by this author on: Oxford Academic PubMed Google Scholar James B. Peter James B. Peter Reprints or correspondence: Dr. James B. Peter, Specialty Laboratories, Inc., 2211 Michigan Ave., Santa Monica, CA 90404. Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 167, Issue 6, June 1993, Pages 1503–1504, https://doi.org/10.1093/infdis/167.6.1503 Published: 01 June 1993
Colour contrast sensitivity in patients with age-related Bruch's membrane changes. (1995)

Patients with bilateral drusen as a manifestation of early age-related macular degeneration (AMD) may have minor psychophysically detectable visual defects in the presence of normal visual acuity. In a variety of retinal diseases, one of the earliest changes in visual processing is an impairment of normal colour vision. This study was undertaken to evaluate colour vision deficits in patients with macular drusen and to determine whether changes in colour contrast sensitivity may occur over time. In a prospective study, colour vision in 84 eyes of 84 patients aged 55-84 years (mean, 68.89 +/- 6.23 years) with macular drusen and clear media was tested using a computer graphics technique. A total of 47 patients were reviewed annually for up to 2 years and measurements were obtained at annual intervals. Colour contrasts sensitivity along protan, deutan and tritan colour confusion lines was determined at a foveal and a parafoveal region. The sensitivity to all stimuli showed large variations between patients. The thresholds for foveal blue-colour contrast sensitivity were elevated and increased during the review period. In contrast, there was no significant change in sensitivity with time for red and green at the foveal or parafoveal region. Tritan threshold changes suggest that the SW cone-receptor population is more susceptible to damage associated with early age-related macular disease than are red or green cones. The results indicate that blue colour contrast sensitivity determined over time may serve as a measure to assess the progression of age-related maculopathy prior to the manifestation of atrophic or exudative macular lesions associated with visual loss.