gebhart/patrepeval huggingface dataset:
Intestinal Absorption of Polymeric Derivatives of the Food Dyes Sunset Yellow and Tartrazine in Rats (1977)

1. Absorption and metabolism of 14C-labelled sunset yellow (FD & C Yellow No. 6), tartrazine (FD & C Yellow No. 5) and high molecular weight polymeric derivatives of the two azo dyes were compared in rats. 2. A trace to 1.5 percent of unchanged monomeric dyes was excreted in urine and bile during the first 24 h after dosing. No unchanged dye was absorbed after administration of the polymeric derivatives. 3. In animals dosed with sunset yellow and its polymer derivative, absorption of the azo-bound cleavage product 1-amino-2-naphthol-6-sulphonic acid was 8.5 and 6.9 percent, respectively, while absorption of the cleavage product sulphanilic acid was 37.4 and 0 percent, respectively. 4. In animals dosed with tartrazine and its polymer derivative, absorption of the cleavage product aminopyrazolone and its metabolites was 4.0 and 4.6 percent, respectively. 5. Azo bond cleavage did not appear to be decreased in the polymer derivatives. However, the sulphanilic acid moiety of both dyes remained attached to the polymer backbone, resulting in a 95 percent decrease in sulphanilic acid absorption with polymeric tartrazine. 6. Decreased absorption of unchanged dyes and certain metabolites with the stable, non-absorbed polymeric derivatives may be significant in developing non-sensitizing substitutes for these two commonly used food colourants.
Temporal encoded F-formation system for social interaction detection (2013)

In the context of a social gathering, such as a cocktail party, the memorable moments are generally captured by professional photographers or by the participants. The latter case is often undesirable because many participants would rather enjoy the event instead of being occupied by the photo-taking task. Motivated by this scenario, we propose the use of a set of cameras to automatically take photos. Instead of performing dense analysis on all cameras for photo capturing, we first detect the occurrence and location of social interactions via F-formation detection. In the sociology literature, F-formation is a concept used to define social interactions, where each detection only requires the spatial location and orientation of each participant. This information can be robustly obtained with additional Kinect depth sensors. In this paper, we propose an extended F-formation system for robust detection of interactions and interactants. The extended F-formation system employs a heat-map based feature representation for each individual, namely Interaction Space (IS), to model their location, orientation, and temporal information. Using the temporally encoded IS for each detected interactant, we propose a best-view camera selection framework to detect the corresponding best view camera for each detected social interaction. The extended F-formation system is evaluated with synthetic data on multiple scenarios. To demonstrate the effectiveness of the proposed system, we conducted a user study to compare our best view camera ranking with human's ranking using real-world data.
The neural cell adhesion molecule is involved in the metastatic capacity in a murine model of lung cancer (2010)

Neural cell adhesion molecule (NCAM) is involved in cell growth, migration, and differentiation. Its expression and/or polysialylation appear to be deregulated in many different cancer types. We employed the lung tumor cell line LP07, syngeneic in BALB/c mice to investigate the role of NCAM in malignant progression. LP07 cells express the three main NCAM isoforms, all of them polysialylated. This cells line, pretreated with an anti-NCAM antibody and inoculated intravenously (i.v.) into syngeneic mice, developed less and smaller lung metastases. In vitro studies showed that NCAM bound antibody inhibited cell growth, mainly due to an increase in apoptosis, associated with a decrease of cyclin D1 and enhanced expression of active caspase 3 and caspase 9. Anti-NCAM-treated LP07 cells showed impairment in their ability to migrate and adhere to several extracellular matrix components. Secreted uPA activity was also reduced. NCAM-140 knocked-down by siRNA in LP07 cells pretreated or not with anti-NCAM showed an impaired metastasizing ability upon i.v. inoculation into mice. These results suggest that anti-NCAM treatment could be mimicking homophilic trans-interactions and NCAM-140 knocked-down impairs heterophilic interactions, both leading to inhibition of metastatic dissemination. The involvement of NCAM in lung tumor progression was confirmed in human NSCLC tumors. Sixty percent of the cases expressed NCAM at tumor cell level. A multivariate analysis indicated that NCAM expression was associated with a shorter overall survival in this homogeneous series of Stages I and II NSCLC patients. NCAM may be able to modulate mechanisms involved in lung carcinoma progression and represents an attractive target to control metastatic progression.
A Review for Synthesis of Nanoflowers (2008)

The data on nanoflower-like nanostructures are generalized for several groups of inorganic compounds (carbon, elemental metals, their alloys and compounds with the elements of V and VI Groups of the Periodic Table), as well as for a few coordination and organic compounds. Their synthetic techniques include oxidation of elemental metals, reduction of metal salts, thermal decomposition of relatively unstable compounds, or electrochemical route. Some current and possible applications of nanoflowers are noted.
Behind the Gates (2004)

In the last twenty years, thousands upon thousands of the upper and middle classes have retreated into gated communities. In 2002 it is estimated that one in eight Americans will live in these exclusive neighborhoods. What has sparked this alarming trend?Behind the Gates is Low's revealing account of what life is like inside these suburban fortresses. After years researching and interviewing families in Long Island, New York and San Antonio, Texas, Low provides an inside view of gated communities to help explain why people flee to these enclaves. Parents with children, young married couples, "empty-nesters," and retirees express their need for safety, their secret fears of a more ethnically diverse America, and their desire to recapture the close-knit, picket-fenced communities of their childhood. Ironically, she shows, gated neighborhoods are in fact no safer than other suburbs, and many who move there are disheartened by the insularity and restrictive rules of the community.Low probes the hopes, dreams, and fears of her subjects to portray the subtle change in American middle-class values marked by the emergence of enclosed communities in the suburbs.
A Numerical Study of Stress Distribution and Fracture Development above a Protective Coal Seam in Longwall Mining (2018)

Coal and gas outbursts are serious safety concerns in the Chinese coal industry. Mining of the upper or lower protective coal seams has been widely used to minimize this problem. This paper presents new findings from longwall mining-induced fractures, stress distribution changes in roof strata, strata movement and gas flow dynamics after the lower protective coal seam is extracted in a deep underground coal mine in Jincheng, China. Two Flac3D models with varying gob loading characteristics as a function of face advance were analyzed to assess the effect of gob behavior on stress relief in the protected coal seam. The gob behavior in the models is incorporated by applying variable force to the floor and roof behind the longwall face to simulate gob loading characteristics in the field. The influence of mining height on the stress-relief in protected coal seam is also incorporated. The stress relief coefficient and relief angle were introduced as two essential parameters to evaluate the stress relief effect in different regions of protected coal seam. The results showed that the rock mass above the protective coal seam can be divided into five zones in the horizontal direction, i.e. pre-mining zone, compression zone, expansion zone, recovery zone and re-compacted zone. The volume expansion or the dilation zone with high gas concentration is the best location to drill boreholes for gas drainage in both the protected coal seam and the protective coal seam. The research results are helpful to understand the gas flow mechanism around the coal seam and guide industry people to optimize borehole layouts in order to eliminate the coal and gas outburst hazard. The gas drainage programs are provided in the final section.
Stereocontrolled Total Synthesis of the Potent Anti-inflammatory and Pro-resolving Lipid Mediator Resolvin D3 and Its Aspirin-Triggered 17<i>R</i>-Epimer (2013)

The first total synthesis of stereochemically pure resolvin D3 and aspirin-triggered resolvin D3 is reported. These enzymatic metabolites of docosahexaenoic acid (DHA) have potent anti-inflammatory and pro-resolving actions. The convergent synthetic strategy is based on enantiomerically pure starting materials, and it is highly stereocontrolled.
Design correlations for mixing tees (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDesign correlations for mixing teesCharles Cozewith and Michael Busko Jr.Cite this: Ind. Eng. Chem. Res. 1989, 28, 10, 1521–1530Publication Date (Print):October 1, 1989Publication History Published online1 May 2002Published inissue 1 October 1989https://pubs.acs.org/doi/10.1021/ie00094a015https://doi.org/10.1021/ie00094a015research-articleACS PublicationsRequest reuse permissionsArticle Views362Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Light-driven hydrogen evolution with a nickel thiosemicarbazone redox catalyst featuring Ni⋯H interactions under basic conditions (2014)

New metal thiosemicarbazone complexes containing phosphine donors were achieved as catalysts for light driven H<sub>2</sub> evolution in a homogeneous environment.
An air–liquid contactor for large-scale capture of CO2 from air (2012)

We present a conceptually simple method for optimizing the design of a gas-liquid contactor for capture of carbon dioxide from ambient air, or 'air capture'. We apply the method to a slab geometry contactor that uses components, design and fabrication methods derived from cooling towers. We use mass transfer data appropriate for capture using a strong NaOH solution, combined with engineering and cost data derived from engineering studies performed by Carbon Engineering Ltd, and find that the total costs for air contacting alone-no regeneration-can be of the order of $60 per tonne CO(2). We analyse the reasons why our cost estimate diverges from that of other recent reports and conclude that the divergence arises from fundamental design choices rather than from differences in costing methodology. Finally, we review the technology risks and conclude that they can be readily addressed by prototype testing.
Reshaping IS Strategic Planning (1990)

In most organizations, there is an increasing investment in strategic planning for information systems and technology. The context and motivation for this type of planning is different from that of the past and, as a result, the planning approach itself is being transformed. Applying this new approach to strategic planning produces high leverage for the enterprise and profoundly changes information systems management.
Fuzzy logic-based solar charge controller for microbatteries (2002)

A severe limitation on the functional capability of remote, autonomous, microelectromechanical (MEMS)-based sensors is the lack of a suitable micropower supply to power these devices. Such sensors often have low power requirements that may be provided by the combination of an energy scavenger (e.g., a solar cell) and a microbattery ("/spl mu/battery") made rechargeable using integrated circuit fabrication methods. While rechargeable /spl mu/batteries and solar cells have been previously demonstrated, the development of a microcharge/discharge controller has not. In this paper we present a novel, fuzzy logic-based solar charge controller that allows control of the charge/discharge of /spl mu/batteries. A breadboard implementation of the controller and its integration with a solar cell and /spl mu/attery is presented. The circuit topology of the /spl mu/battery controller is based on a buck converter design. During charging, the solar cell's operating point is adjusted by modulating the duty cycle of the buck converter's switching MOSFET using a fuzzy logic control algorithm to optimally charge the /spl mu/battery. Discharge data on the /spl mu/batteries and current-voltage characteristics of the solar cell are presented and the fuzzy logic model development for the charge control are also presented.
Aggregation-induced emission enhancement of a meso-trifluoromethyl BODIPY via J-aggregation (2013)

A CF3-BODIPY forms strongly luminescent aggregates, which contrasts with the quenched condensed-phase photophysics that are typical for BODIPY dyes. Examination of the luminescent properties of these aggregates – narrow red-shifted absorption and emission bands, minimal Stokes shift and increased fluorescence rate constants – and of the solid-state packing of the dye establish the CF3-BODIPY as the first structurally characterized genuine BODIPY J-aggregate.
Knowledge-Based Conformer Generation Using the Cambridge Structural Database (2018)

Fast generation of plausible molecular conformations is central to molecular modeling. This paper presents an approach to conformer generation that makes extensive use of the information available in the Cambridge Structural Database. By using geometric distributions derived from the Cambridge Structural Database, it is possible to create biologically relevant conformations in the majority of cases analyzed. The paper compares the performance of the approach with previously published evaluations, and presents some cases where the method fails. The method appears to show significantly improved performance in reproduction of the conformations of structures observed in the Cambridge Structural Database and the Protein Data Bank as compared to other published methods of a similar speed.
Research advances of microalloying Al-Zn-Mg-( Cu) series aluminum alloy (2014)

Requirement for high-performance aluminum alloy is increasingly severe with the development of aerospace industry. Microalloying is an important approach to improve the mechanical properties of aluminum alloys,and its research has been a global focus. The property of rare-earth( RE) elements are active and easy to combine with aluminum alloy matrix and solute elements,so they can effectively improve the microstructure of Al-Zn-Mg-( Cu) aluminum alloy and significantly enhance its comprehensive performance. Microalloying of non rare earth elements can compensate the negatives of that of rare earth elements,so it is widely applied. This paper reviews the function mechanism of rare-earth elements Sc,Er,and Ce and regular elements Zr,Ag,Sn,Cr and Sr to the microalloying of Al-Zn-Mg-( Cu) aluminum alloys. We further present some suggestions for the development directions of microalloying of Al-Zn-Mg-( Cu) aluminum alloys.
Multiple Locus Linkage Analysis of Genomewide Expression in Yeast (2005)

With the ability to measure thousands of related phenotypes from a single biological sample, it is now feasible to genetically dissect systems-level biological phenomena. The genetics of transcriptional regulation and protein abundance are likely to be complex, meaning that genetic variation at multiple loci will influence these phenotypes. Several recent studies have investigated the role of genetic variation in transcription by applying traditional linkage analysis methods to genomewide expression data, where each gene expression level was treated as a quantitative trait and analyzed separately from one another. Here, we develop a new, computationally efficient method for simultaneously mapping multiple gene expression quantitative trait loci that directly uses all of the available data. Information shared across gene expression traits is captured in a way that makes minimal assumptions about the statistical properties of the data. The method produces easy-to-interpret measures of statistical significance for both individual loci and the overall joint significance of multiple loci selected for a given expression trait. We apply the new method to a cross between two strains of the budding yeast Saccharomyces cerevisiae, and estimate that at least 37% of all gene expression traits show two simultaneous linkages, where we have allowed for epistatic interactions. Pairs of jointly linking quantitative trait loci are identified with high confidence for 170 gene expression traits, where it is expected that both loci are true positives for at least 153 traits. In addition, we are able to show that epistatic interactions contribute to gene expression variation for at least 14% of all traits. We compare the proposed approach to an exhaustive two-dimensional scan over all pairs of loci. Surprisingly, we demonstrate that an exhaustive two-dimensional scan is less powerful than the sequential search used here. In addition, we show that a two-dimensional scan does not truly allow one to test for simultaneous linkage, and the statistical significance measured from this existing method cannot be interpreted among many traits.
[New progress in noninvasive method of blood glucose measurement using FT-mid-IR spectroscopy]. (2010)

The blood glucose concentrations of volunteers from diabetes patients and healthy adults (all patients and volunteers who joined this experiment gave their consents) were measured by using a modified WQF-200 FTIR spectrometer with a newly designed ATR accessory from the Beijing Rayleigh Analytical Instrument Corp. The determination basis for this technique from the physiological point of view is also discussed based on the experimental results, which indicated that the glucose measured by the FT-Mid-IR ATR instrument is from the secretions on the skin and glucose components within the body. The secreted glucose components will increase with the time increasing. The authors' previous study demonstrated 1 120 cm(-1) band as an index to characterize the blood glucose. During the experiments, the authors used the band of 1 455 cm(-1) as internal standard because of its stability, and because the relative intensity of I1 120/I1 455 band possesses the higher sensitivity. Meanwhile, from the spectra, the relative intensity of I1 120/I1 455 band of the glucose in both sources exhibits a linear relationship with blood glucose concentration within the body. The dried blood has the similar spectra as fingers'. The fingers' spectra will exhibit higher sensitivity if the time of measurement is longer after washing hand, and the results showed that when measured 10 minutes after washing hand, the sensitivity will be higher than that when measured 4 minutes after washing hand. All the results can be used in promoting a convenient, rapid and noninvasive way to monitor the continuous variation of blood glucose concentration of diabetes patients in real time.
Conserved residues that modulate protein<i>trans</i>-splicing of<i>Npu</i>DnaE split intein (2014)

The first crystal trans-structure of a naturally occurring split intein has been determined for the Npu (Nostoc punctiforme PCC73102) DnaE split intein. Guided by this structure, the residues NArg50 and CSer35, well conserved in DnaE split inteins, are identified to be critical in the trans-splicing of Npu DnaE split intein. An in vitro splicing assay demonstrates that NArg50 and CSer35 play synergistic roles in modulating its intein activity. The C-terminal CAsn36 exhibits two orientations of its side chain and interacts with both NArg50 and CSer35 through hydrogen bonding. These interactions likely facilitate the cyclization of asparagine in the course of protein splicing. The mutation of either residue reduces intein activity, and correlates with the low activity of the Ssp (Cyanobacterium synechocystis sp. strain PCC6803) DnaE split intein. On the other hand, NArg50 also forms a hydrogen bond with the highly conserved F-block CAsp17, thus influencing the N–S acyl shift during N-terminal cleavage. Sequence alignments show that residues NArg50 and CSer35 are rather conserved in those split inteins that lack a penultimate histidine residue. The conserved non-catalytic residues of split inteins modulate the efficiency of protein trans-splicing by hydrogen-bond interactions with the catalytic residues at the splice junction.
A “Side‐on” Superoxonickel Complex [LNi(O<sub>2</sub>)] with a Square‐Planar Tetracoordinate Nickel(II) Center and Its Conversion into [LNi(μ‐OH)<sub>2</sub>NiL] (2008)

Radically mild: The first room-temperature isolable, structurally characterized superoxonickel(II) complex 1 with a square-planar tetracoordinate NiII center is capable of gentle oxygen-transfer reactions to form the proposed intermediate 2, which acts as a hydrogen scavenger and dimerizes to homovalent complex 3 with both square-planar (low-spin) and tetrahedral (high-spin) NiII centers. L=CH{C(Me)(2,6-iPr2C6H3N}2. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z802234_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Using SOAP Technology in Document Management System (2005)

This paper gives an idea of establishing document management system to resolve the problems in document management by hand and gives a scheme by using SOAP technology.
Detection of noncovalent FKBP-FK506 and FKBP-Rapamycin complexes by capillary electrophoresis-mass spectrometry and capillary electrophoresis-tandem mass spectrometry (1995)

The well known biospecific noncovalent receptor-ligand association complexes between the immunophilin FKBP and the immunosuppressive drugs FK506 and Rapamycin (RM) were investigated by on-line capillary electrophoresis-mass spectrometry (CE-MS) under selected ion monitoring (SIM) conditions and by CE-MS with tandem mass spectrometry (CE-MS/MS) under selected reaction monitoring (SRM) conditions. Solutions of hFKBP (33.3 µM) were dissolved in 50 mM ammonium acetate at pH 7.5. Samples that contained 100 µM of FK506 or RM also were prepared under the same solution conditions. By using these aqueous pH neutral conditions, samples were analyzed by SIM CE-MS and SRM CE-MS and the target complexes were separated by CE with mass spectrometer detection of the individual complexes between FKBP and FK506 [hFKBP + FK506 + 7HJ(7+) as well as FKBP and RM [hFKBP + RM + 7HJ(7+). In an experiment where a mixture of FK506 and RM was analyzed in the presence of FKBP, a nine-to-one ratio of ion current abundances between the RM and FK506 complexes was observed as reported in the literature from other studies. These results suggest that CE-MS and CE-MS/MS may be yet another analytical method for studying noncovalent interactions of biologically important macromolecules under physiological conditions.