gebhart/patrepeval huggingface dataset:
TV Scout: Guiding Users from Printed TV Program Guides to Personalized TV Recommendation (2002)

In this paper, we present TV Scout, a recommendation system providing users with personalized TV schedules. The TV Scout architecture addresses the “cold-start” problem of information filtering systems, i.e. that filtering systems have to gather information about the user’s interests before they can compute personalized recommendations. Traditionally, gathering this information involves upfront user effort, resulting in a substantial entry barrier. TV Scout is designed to avoid this problem by presenting itself to new users not as a filtering system, but as a retrieval system where all user effort leads to an immediate result. While users are dealing with this retrieval functionality, the system continuously and unobtrusively gathers information about the user’s interests from implicit feedback and gradually evolves into a filtering system. An analysis of log file data gathered with over 10,000 registered online users shows that over 85% of all first-time users logged in again, suggesting that the described architecture is successful in lowering the entry barrier.1
Panhandle PCR for cDNA: A rapid method for isolation of <i>MLL</i> fusion transcripts involving unknown partner genes (2000)

Identifying translocations of the MLL gene at chromosome band 11q23 is important for the characterization and treatment of leukemia. However, cytogenetic analysis does not always find the translocations and the many partner genes of MLL make molecular detection difficult. We developed cDNA panhandle PCR to identify der(11) transcripts regardless of the partner gene. By reverse transcribing first-strand cDNAs with oligonucleotides containing coding sequence from the 5' MLL breakpoint cluster region at the 5' ends and random hexamers at the 3' ends, known MLL sequence was attached to the unknown partner sequence. This enabled the formation of stem-loop templates with the fusion point of the chimeric transcript in the loop and the use of MLL primers in two-sided PCR. The assay was validated by detection of the known fusion transcript and the transcript from the normal MLL allele in the cell line MV4-11. cDNA panhandle PCR then was used to identify the fusion transcripts in two cases of treatment-related acute myeloid leukemia where the karyotypes were normal and the partner genes unknown. cDNA panhandle PCR revealed a fusion of MLL with AF-10 in one case and a fusion of MLL with ELL in the other. Alternatively spliced transcripts and exon scrambling were detectable by the method. Leukemias with normal karyotypes may contain cryptic translocations of MLL with a variety of partner genes. cDNA panhandle PCR is useful for identifying MLL translocations and determining unknown partner sequences in the fusion transcripts.
Dependence of the blocking temperature in exchange biased ferromagnetic/antiferromagnetic bilayers on the thickness of the antiferromagnetic layer (2007)

Based on the size-dependent exchange interaction of antiferromagnets, the blocking temperature in exchange-biased ferromagnetic/antiferromagnetic bilayers is modelled as a function of the thickness of the antiferromagnetic layer. It is found that this temperature decreases with decreasing layer thickness, which agrees with the available experimental measurements for Fe3O4/CoO, NiO/NiFe, CoNiO/NiFe, IrMn/NiFe, Py/IrMn, IrMn/CoFe, FeMn/NiFe, MnPt/CoFe and FeF2/Fe bilayers. The correspondence between the model predictions and experimental evidence results in a deeper understanding of the present models for the above phenomena.
Analysis of a probe-fed microstrip disk antenna (1991)

The input impedance of a probe-fed, annular-ring-loaded, circular-disk microstrip antenna is analysed using three methods of increasing complexity and sophistication. The first method uses a new variational formula which is more suitable for antennas driven by a voltage gap. The second method uses a mode-matching method where the field inside the coaxial line is expanded in terms of waveguide modes. The third method uses the mode-matching method with a diaphragm at the coaxial aperture. The mode-matching methods are identical to the variational formula under the single-mode approximation. However, when a diaphragm is present, the single-mode approximation is insufficient, implying that the variational formula is inaccurate when a diaphragm exists. The theory is used to study the effect of the gap capacitance at the coaxial aperture on the input impedance of the microstrip antenna. It is found that this gap capacitance is important when the dielectric substrate is thick.
REVIEW OF CURRENT VERTEBRATE PESTICIDES (1962)

The history of development, physical properties, mode of action, methods of use, and typical applications vertebrate pesticides are reviewed and discussed. Active ingredients reviewed are strychnine, sodium monofluoroacetate (Compound 1080), zinc phosphide, cyanide, red squill, ANTU (alpha-naphthylthiourea), five anticoagulants, arsenic trioxide, endrin. Of these, ANTU, anticoagulants, and red squill have been used in tracking powders for rats and mice. Fumigants used for control field rodents in their burrows have included calcium cyanide, carbon disulfide, and pyrotechnic (gas) cartridges that produce carbon monoxide. A list of references is included.
Escherichia coli thioredoxin folds into two compact forms of different stability to urea denaturation (1989)

The urea-induced denaturation of Escherichia coli thioredoxin and thioredoxin variants has been examined by electrophoresis on urea gradient slab gels by the method of Creighton [Creighton, T. (1986) Methods Enzymol. 131, 156-172]. Thioredoxin has only two cysteine residues, and these form a redox-active disulfide at the active site. Oxidized thioredoxin-S2 and reduced thioredoxin-(SH)2 each show two folded isomers with a large difference in stability to urea denaturation. The difference in stability is greater for the isomers of oxidized than for the isomers of reduced thioredoxin. At 2 degrees C, the urea concentrations at the denaturation midpoint are approximately 8 and 4.3 M for the oxidized isomers and 4.8 and 3.7 M for the reduced isomers. The difference between the gel patterns of samples applied in native versus denaturing buffer, and at 2 and 25 degrees C, is characteristic for the involvement of a cis-proline-trans-proline isomerization. The data very strongly suggest that the two folded forms of different stabilities correspond to the cis and trans isomers of the highly conserved Pro 76 peptide bond, which is cis in the crystal structure of oxidized thioredoxin. Urea gel experiments with the mutant thioredoxin P76A, with alanine substituted for proline at position 76, corroborate this interpretation. The electrophoretic banding pattern diagnostic for an involvement of proline isomerization in urea denaturation is not observed for oxidized P76A. In broad estimates of delta G degree for the native-denatured transition, the difference in delta G degree (no urea) between the putative cis and trans isomers of the Ile 75-Pro 76 peptide bond is approximately 3 kcal/mol for oxidized thioredoxin and approximately 1.5 kcal/mol for reduced thioredoxin. Since cis oxidized thioredoxin is much more stable than trans, folded oxidized thioredoxin is essentially all cis. In folded reduced thioredoxin, cis and trans interconvert slowly, on the minute time scale at 2 and 25 degrees C. In the absence of urea, the folded reduced thioredoxin is less than a few percent trans. Three additional mutants with additions or substitutions at the active site also show electrophoresis banding patterns consistent with a difference in stability between cis and trans isomers.
Ammonium cascade molecules (1992)

K. Rengan and R. Engel, J. Chem. Soc., Chem. Commun., 1992, 757 DOI: 10.1039/C39920000757
[Prokaryotic expression and identification of human papillomavirus type 16 E7 protein encoding gene]. (2006)

The construction of the prokaryotic recombinant plasmid pET32/E7 and the successful expression of the recombinant protein HPV16 E7-TRX would strongly promote the research of the biological properties and the transformational mechanism of the HPV16 E7 protein on the specific cells.
Effect of forming gas annealing on the ferroelectric properties of Hf0.5Zr0.5O2 thin films with and without Pt electrodes (2013)

The effects of forming gas annealing (FGA) on the ferroelectric properties of Hf0.5Zr0.5O2 (HZO) films were examined. Although the H-incorporation during FGA degrades the ferroelectric properties of Hf0.5Zr0.5O2 films, the degree of degradation was much lower compared with other ferroelectrics, such as Pb(Zr,Ti)O3. Pt worked as a catalyst for H-incorporation, and maximum 2Pr loss of ∼40% occurred. However, the insertion of a ∼20-nm-thick TiN layer between Pt and Hf0.5Zr0.5O2 decreased the degradation to ∼12%. Hf0.5Zr0.5O2 is more resistant to degradation by FGA compared with the conventional ferroelectrics, which is a highly promising result for next-generation ferroelectric memory.
Cinema of Common Sense (1964)

Research Article| July 01 1964 Cinema of Common Sense Colin Young Colin Young Search for other works by this author on: This Site PubMed Google Scholar Film Quarterly (1964) 17 (4): 26–40. https://doi.org/10.2307/1210651 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Colin Young; Cinema of Common Sense. Film Quarterly 1 July 1964; 17 (4): 26–40. doi: https://doi.org/10.2307/1210651 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentFilm Quarterly Search This content is only available via PDF. Copyright 1964 The Regents of the University of California Article PDF first page preview Close Modal You do not currently have access to this content.
Many-Body Physics with Trapped Ions (2011)

Direct experimental access to some of the most intriguing quantum phenomena is not granted due to the lack of precise control of the relevant parameters in their naturally intricate environment. Their simulation on conventional computers is impossible, since quantum behaviour arising with superposition states or entanglement is not efficiently translatable into the classical language. However, one could gain deeper insight into complex quantum dynamics by experimentally simulating the quantum behaviour of interest in another quantum system, where the relevant parameters and interactions can be controlled and robust effects detected sufficiently well. We report on the progress in experimentally simulating quantum many-body physics with trapped ions.
The hallucinogenic herb <i>Salvia divinorum</i> and its active ingredient salvinorin A inhibit enteric cholinergic transmission in the guinea‐pig ileum (2005)

Salvia divinorum is a widespread hallucinogenic herb traditionally employed for divination, as well as a medicament for several disorders including disturbances of gastrointestinal motility. In the present study we evaluated the effect of a standardized extract from the leaves of S. divinorum (SDE) on enteric cholinergic transmission in the guinea-pig ileum. SDE reduced electrically evoked contractions without modifying the contractions elicited by exogenous acetylcholine, thus suggesting a prejunctional site of action. The inhibitory effect of SDE on twitch response was abolished by the opioid receptor antagonist naloxone and by the kappa-opioid antagonist nor-binaltorphimine, but not by naltrindole (a delta-opioid receptor antagonist), CTOP (a mu-opioid receptor antagonist), thioperamide (a H(3) receptor antagonist), yohimbine (an alpha(2)-receptor antagonist), methysergide (a 5-hydroxytryptamine receptor antagonist), N(G)-nitro-L-arginine methyl ester (an inhibitor of NO synthase) or apamin (a blocker of Ca(2+)-activated K(+) channels). Salvinorin A, the main active ingredient of S. divinorum, inhibited in a nor-binaltorphimine- and naloxone-sensitive manner electrically induced contractions. It is concluded that SDE depressed enteric cholinergic transmission likely through activation of kappa-opioid receptors and this may provide the pharmacological basis underlying its traditional antidiarrhoeal use. Salvinorin A might be the chemical ingredient responsible for this activity.
An efficient error concealment implementation for MPEG-4 video streams (2002)

This paper presents some error concealment results regarding damaged MPEG-4 bistreams. The chosen concealment algorithms are designed to fit in real-time decoders and provide a better PSNR and visually more plausible pictures than basic concealment techniques. In addition, the encoder impact on the visual quality of the reconstruction in presence of channel errors is highlighted.
Physical Principles and Extant Biology Reveal Roles for RNA-Containing Membraneless Compartments in Origins of Life Chemistry (2018)

This Perspective focuses on RNA in biological and nonbiological compartments resulting from liquid-liquid phase separation (LLPS), with an emphasis on origins of life. In extant cells, intracellular liquid condensates, many of which are rich in RNAs and intrinsically disordered proteins, provide spatial regulation of biomolecular interactions that can result in altered gene expression. Given the diversity of biogenic and abiogenic molecules that undergo LLPS, such membraneless compartments may have also played key roles in prebiotic chemistries relevant to the origins of life. The RNA World hypothesis posits that RNA may have served as both a genetic information carrier and a catalyst during the origin of life. Because of its polyanionic backbone, RNA can undergo LLPS by complex coacervation in the presence of polycations. Phase separation could provide a mechanism for concentrating monomers for RNA synthesis and selectively partition longer RNAs with enzymatic functions, thus driving prebiotic evolution. We introduce several types of LLPS that could lead to compartmentalization and discuss potential roles in template-mediated non-enzymatic polymerization of RNA and other related biomolecules, functions of ribozymes and aptamers, and benefits or penalties imparted by liquid demixing. We conclude that tiny liquid droplets may have concentrated precious biomolecules and acted as bioreactors in the RNA World.
CARDIAC SYNDROMES COMPLICATING DIABETES AND THEIR TREATMENT (1943)

While it is true that common diseases must often co-exist in the same patient, the frequent association of heart disease with diabetes is the expression of a causal relationship. In the present paper the evidence for this statement will be examined. Thereafter an analysis will be made of 49 patients with heart disease and diabetes, with a discussion of the nature of the anginal and other cardiac syndromes developing, and typical clinical examples will be mentioned. Lastly, schemes of treatment B I on August 20,
Performance of lignite-syngas operated tubular solid oxide fuel cell (2008)

Results of computations of a single fuel cell tube fuelled with lignite-derived synthesis gas have been presented. Gasifier reactions have been modelled as well as raw syngas pre-processing in pre-reformer to obtain fuel at a suitable steam-to-carbon ratio. The model employed in the analysis can cope with arbitrary mixture of hydrogen, steam, carbon monoxide, carbon dioxide and methane. Calculations have been conducted for various steam-to-air ratios in the gasifier.
Technical comments on the bioassay of erythropoietin. (1978)

Quantitative erythropoietin determinations can only be obtained after the examination of both Standard and Test materials in a multiple dose parallel line bioassay with appropriate statistical control. The expression of results in erythropoietin units (implying quantitation) in the absence of similar dose-response relationships for Standard and Test materials can lead to errors in the estimated potency which differ markedly from the true potency. Results obtained from one-dose test systems cannot therefore be considered quantitative. Criteria which allow valid quantitation of bioassay results are discussed. Where these cannot be fulfilled, it is suggested that the results should be expressed only in terms of the measured parameter, e.g. 59Fe uptake, per constant volume of test solution.
<i>Pax-3</i> is necessary for migration but not differentiation of limb muscle precursors in the mouse (1996)

The limb muscles of vertebrates are derived from precursor cells that migrate from the lateral edge of the dermomyotome into the limb bud. Previous studies have shown that the paired domain-containing transcription factor Pax-3 is expressed in the limb in cells that are precursors for limb muscles (Williams, B. and Ordahl, C.P. (1994) Development 120, 785-796). In splotch (Pax-3-) embryos, the limb muscles fail to develop and cells expressing Pax-3 are no longer found in the limb. In this paper we have analyzed the role of Pax-3 in the migration and subsequent differentiation of limb muscle precursors. By labeling somites adjacent to the prospective forelimb with the lipophilic dye DiI, we have shown that cells derived from these somites do not migrate into the limbs of splotch mice. The failure of limb muscle precursors to invade the limb in splotch mice is associated with the absence of c-met expression in premigratory cells, together with a change in the morphology of the ventral dermomyotome. In addition, we have shown the lateral half of somites derived from day E9.25 splotch embryos can undergo muscle differentiation when grafted into the limb bud stage 20 chick host embryos. Our results indicate that Pax-3 regulates the migration of limb muscle precursors into the limb and is not required for cells in the lateral somite to differentiate into muscle.
Nanocomposite and Nanostructured Carbon-based Films as Growth Substrates for Bone Cells (2011)

Lucie Bacakova1, Lubica Grausova1, Jiri Vacik2, Alexander Kromka3, Hynek Biederman4, Andrei Choukourov4 and Vladimir Stary5 1Department of Growth and Differentiation of Cell Populations, Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, 2Nuclear Physics Institute, Academy of Sciences of the Czech Republic & Research Center Rez, 3Institute of Physics, Academy of Sciences of the Czech Republic, Prague, 4Department of Macromolecular Physics, Faculty of Mathematics and Physics, Charles University, Prague, 5Faculty of Mechanical Engineering, Czech Technical University, Prague, Czech Republic
LEDs on curved ceramic substrate with primary optics for modification of luminous intensity (2011)

Unlike the conventional LED luminary with a planar substrate and only the forward emission, the proposed LED luminary with a curved ceramic substrate can perform both the forward and the backward emissions. Assembled with the proper primary optics, an illustrated LED bulb has been designed, fabricated and measured. The measured luminous intensity of the LED bulb has shown the backward emission and designed distribution with the beam-angle of 133°. To broaden the application areas, such a LED bulb on a curved substrate has been modularized as a streetlight. The measured results of the proposed streetlight have shown that the beam angle of the luminous intensity and the luminaire efficiency are 132° and 86%, respectively. Meanwhile, its luminous characteristics also fit the standard for lighting design of urban roads.asei.c
Senile dementia, alzheimer type: A distinct entity in the immunosenescence? (1990)

Since previous data have provided conflicting results on immunoresponsiveness in senile dementia, Alzheimer type (SDAT), we evaluated the immune function in groups of SDAT patients and aged and young donors. In comparison to the younger subjects, SDAT and aged subjects did not exhibit significant differences in lymphocyte surface markers. Both groups of aged donors showed decreased B cell polyclonal responsiveness in a nonspecific T cell-driven B lymphocyte differentiation system. The use of an antigen-specific induction assay revealed an imbalance of T helper (Th) or T suppressor function in the elderly, while SDAT individuals were characterized by decreased Th activity. At the same time, aged individuals manifested an impairment of leukocyte-inhibiting factor (LIF) and lymphocyte-derived chemotactic factor production; a selective deficit of LIF release was seen in SDAT. Finally, elderly individuals displayed a decline of polymorphonuclear cell (PMN)-mediated functions and monocyte phagocytosis; only a decrease in PMN response was observed in SDAT. These results reveal discrepancies in impaired immune responses between SDAT and aging.
Human action classification based on sequential bag-of-words model (2014)

Recently, approaches utilizing spatial-temporal features have achieved great success in human action classification. However, they typically rely on bag-of-words (BoWs) model, and ignore the spatial and temporal structure information of visual words, bringing ambiguities among similar actions. In this paper, we present a novel approach called sequential BoWs for efficient human action classification. It captures temporal sequential structure by segmenting the entire action into sub-actions. Each sub-action has a tiny movement within a narrow range of action. Then the sequential BoWs are created, in which each sub-action is assigned with a certain weight and salience to highlight the distinguishing sections. It is noted that the weight and salience are figured out in advance according to the sub-action's discrimination evaluated by training data. Finally, those sub-actions are used for classification respectively, and voting for united result. Experiments are conducted on UT-interaction dataset and Rochester dataset. The results show its higher robustness and accuracy over most state-of-the-art classification approaches.
CYP2C19 genotypes in the pharmacokinetics/pharmacodynamics of proton pump inhibitor-based therapy of<i>Helicobacter pylori</i>infection (2009)

The eradication rates of H. pylori infection are significantly different between patients who are CYP2C19 extensive metabolizers and poor metabolizers, partly because of the differences in the PK and PD of PPIs. Nonetheless, the differences can be improved by adjusting the regimens of PPIs and using antibiotics that have less H. pylori-resistance.
Powering Implantable Telemetry Devices from Localized Magnetic Fields (2007)

This paper presents a novel method of inductively powering an implantable telemetry device over a large area. The system is based around an array of individually tuned series resonant circuits distributed across a charging pad. By varying the frequency of the driving voltage, the location of the charging field is changed. Presented are a method of controlling the resonant frequency and techniques for determining the geometry of the charging pad. Results from a nine coil system operating between 97 kHz and 209 kHz are given which can deliver 100 mW to an implanted telemeter at a height of 5cm above the charging pad.
IgorFs: A Distributed P2P File System (2008)

IgorFs is a distributed, decentralized peer-to-peer (P2P) file system that is completely transparent to the user. It is built on top of the Igor peer-to-peer overlay network, which is similar to Chord, but provides additional features like service orientation or proximity neighbor and route selection. IgorFs offers an efficient means to publish data files that are subject to frequent but minor modifications. In our demonstration we show two use cases for IgorFs: the first example is (static) software-distribution and the second example is (dynamic) file distribution.