gebhart/patrepeval huggingface dataset:
Technology Benchmarking of High Resolution Structures on LTCC for Microwave Circuits (2006)

Low temperature co-fired ceramics (LTCC) is being widely used for microwave circuits. The BMBF funded R&D-project KERAMIS focuses on larger implementation of functionality in LTCC substrates to allow designs with "standard" MMICs. Target applications are circuits for multimedia satellite communications. In order to add more functionality in LTCC, current patterning limits of line width and line separation (100 mum) need to be extended. Four different technologies are considered candidates for higher resolution: a) fine line printing technology with special screens, b) photo-imageable pastes, c) etching of thick film conductors (co- and post-fired) and d) thin films on LTCC. For this purpose, a test coupon was designed and manufactured by the consortium members. The artwork contains lines, line transitions, ring resonators (microstrip and stripline), edge-coupled filters, DC blocking structures, and various lines for DC resistance testing. The smallest gap definition is 50 mum. Two substrate materials, Du Pont tape 951 and 943, are included in the study. Besides the main frequency band of interest in the project (17-22 GHz), these structures have been characterised up to 50 GHz. Electrical results are correlated to physical measurements of the features (line width, spaces and tolerances). Data are evaluated with respect to performance, manufacturability, and yield
ATM Card Security Using Bio-Metric and Message Authentication Technology (2018)

In existing ATM system, most often only personal identification number (PIN) is used to verify authentic user which is not secured enough as it is very easy to copy. Sometimes thieves have a very strong way to steal account information, that's why bio-metric verification system can be a firm solution. The objective of this paper, is to provide a more secured method using bio-metric features and message authentication technique. In our proposed method, PIN verification is combined with fingerprint recognition, to identify a customer during ATM transaction. Fingerprint is verified using efficient minutiae feature extraction algorithm. To assure the security while doing transaction through swipe machine, the client will confirm the transaction by an approval message through GSM technology. In both cases, location will be identified through GPS. If any illegitimate person tries to use the card it will automatically be blocked by the system and detail information will be sent to the customer through the message. Hence, the proposed method will provide more security by identifying and reducing the frauds.
Location, Location, Location (2007)

Neurons may be particularly sensitive to disruptions in transcription factor trafficking. Survival and injury signals must traverse dendrites or axons, in addition to soma, to affect nuclear transcriptional responses. Transcription factors exhibit continued nucleocytoplasmic shuttling; the predominant localization is regulated by binding to anchoring proteins that mask nuclear localization/export signals and/or target the factor for degradation. Two functional groups of karyopherins, importins and exportins, mediate RanGTPase-dependent transport through the nuclear pore. A growing number of recent studies, in Alzheimer, Parkinson, and Lewy body diseases, amyotrophic lateral sclerosis, and human immunodeficiency virus encephalitis, implicate aberrant cytoplasmic localization of transcription factors and their regulatory kinases in degenerating neurons. Potential mechanisms include impaired nuclear import, enhanced export, suppression of degradation, and sequestration in protein aggregates or organelles and may reflect unmasking of alternative cytoplasmic functions, both physiologic and pathologic. Some "nuclear" factors also function in mitochondria, and importins are also involved in axonal protein trafficking. Detrimental consequences of a decreased nuclear to cytoplasmic balance include suppression of neuroprotective transcription mediated by cAMP- and electrophile/antioxidant-response elements and gain of toxic cytoplasmic effects. Studying the pathophysiologic mechanisms regulating transcription factor localization should facilitate strategies to bypass deficits and restore adaptive neuroprotective transcriptional responses.
The role of antioxidant therapy in the treatment of male infertility (2010)

Oxidative stress contributes to defective spermatogenesis leading to male factor infertility. The aim of this study was to review the current literature on the effects of various antioxidants to improve fertilisation and pregnancy rates. The sources of literature were Pubmed and the Cochrane data base. Reviewing the current literature revealed that Carnitines and vitamin C and E have been clearly shown to be effective by many well-conducted studies and may be considered as a first line treatment. The efficacy of antioxidants, such as glutathione, selenium and coenzyme Q10 has been demonstrated by few, but well-performed studies, and may be considered second line treatment. There is, however, a need for further investigation with randomised controlled studies to confirm the efficacy and safety of antioxidant supplementation in the medical treatment of idiopathic male infertility as well as the need to determine the ideal dose of each compound to improve semen parameters, fertilisation rates and pregnancy outcomes.
The OSI network layer: Standards to cope with the real world (1983)

Two key aspects of the OSI Network Layer which require standardization are the definition of the "service" provided by the Network Layer to the Transport Layer and the specification of the way in which "real networks" are to be utilized to provide this "Network Service." This paper describes the results of the work to date by CCITT and ISO in these two very important areas: 1) the Network Service Definition which is near final agreement; and 2) the emerging Network Layer "internal architecture" which is being used to discuss and develpoment strategies for internetworking with real networks.
Comparison of Different Assays for the Quantitation of FK 506 Levels in Blood or Plasma (1994)

In a prospective study, we evaluated the analytical performance of different assays for the quantitation of FK 506 in blood and plasma. The new whole blood IMX assay was compared with four modifications (liquid/liquid or solid/liquid extraction of blood or plasma respectively) of the standard enzyme-linked immunosorbent assay (ELISA). Both assays utilize the same monoclonal antibody for detection of FK 506. Using isolated FK 506 metabolites generated in vitro, this antibody was shown to recognize not only the unmodified parent drug but also FK 506 metabolites. In stable liver-grafted patients, sensitivity of both modifications of the whole blood ELISA was adequate. In contrast, in some stable patients, plasma ELISA was not able to detect FK 506; this was observed mainly after liquid/liquid extraction of FK 506. Sensitivity of the IMX assay was also low; in six of 10 stable liver-grafted patients, IMX levels were below the limit of detection. In all assays, FK 506 levels were found to be elevated during episodes of liver dysfunction; a possible explanation for this effect would be that of accumulation of cross-reacting FK 506 metabolites. As FK 506 metabolites are known to be less immunosuppressive than the parent drug, liver function should always be taken into account if IMX or ELISA levels are used for drug monitoring.
IR2VI: Enhanced Night Environmental Perception by Unsupervised Thermal Image Translation (2018)

Context enhancement is critical for night vision (NV) applications, especially for the dark night situation without any artificial lights. In this paper, we present the infrared-to-visual (IR2VI) algorithm, a novel unsupervised thermal-to-visible image translation framework based on generative adversarial networks (GANs). IR2VI is able to learn the intrinsic characteristics from VI images and integrate them into IR images. Since the existing unsupervised GAN-based image translation approaches face several challenges, such as incorrect mapping and lack of fine details, we propose a structure connection module and a region-of-interest (ROI) focal loss method to address the current limitations. Experimental results show the superiority of the IR2VI algorithm over baseline methods.
Realising the Vision: Implementing Learning in the Workplace and Community at Victoria University (VU) (2010)

This paper outlines the process of implementing Learning in the Workplace and C ommunity (LiWC) - Victoria University’s term for Work Integrated L earning - into all courses offered at VU in Melbourne, Australia. International Conference on Work Integrated Learning University-Industry Collaboration for Real Life Education, Hong Kong 2010 World Association of Cooperative Education
Nanoblossoms:  Light-Induced Conformational Changes of Cationic Polyelectrolyte Stars in the Presence of Multivalent Counterions (2006)

We analyze the structure of star-shaped polyelectrolytes in the presence of di- and trivalent counterions, and we use the gained knowledge to manipulate the polyelectrolyte's conformation by light. By applying dynamic light scattering and atomic force microscopy, we demonstrate that, at constant ionic strength, the arms of the cationic polyelectrolyte retract when adding multivalent counterions. Adding trivalent hexacyanocobaltate(III) ions leads to a collapse of the polyelectrolyte star even at low concentrations. This is shown by analysis of the star polyelectrolytes in solution as well as in the adsorbed state on mica surfaces. Considerably higher salt concentrations are necessary to obtain the same contraction of the polyelectrolyte star if the divalent tetracyanonickelate(II) ions are used. Sufficiently high multivalent counterion concentration leads finally to the precipitation of the polymer from the solution. We demonstrate that we can switch a polyelectrolyte star from the collapsed to the expanded state by transforming the trivalent hexacyanocobaltate(III) ions into a mixture of mono- and divalent ions by UV light. Thus, these collapsed stars react to light like "nanoblossoms". Moreover, polyelectrolyte stars precipitated through addition of the trivalent hexacyanocobaltate(III) ions can be redissolved by irradiation with light (photoinduced dissolution). Hence, the conformation and interaction of star polyelectrolytes can be switched by light. Possible applications of this novel way of manipulating polymers are discussed.
JAPAN-U.S. COLLABORATION: (1989)

RETURN TO ISSUEPREVNewsNEXTJAPAN-U.S. COLLABORATION:New merger involves two collegesJAMES KRIEGERCite this: Chem. Eng. News 1989, 67, 33, 4Publication Date (Print):August 14, 1989Publication History Published online10 November 2010Published inissue 14 August 1989https://doi.org/10.1021/cen-v067n033.p004Copyright © 1989 American Chemical SocietyArticle Views5Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (171 KB) SUBJECTS:Students Get e-Alerts
The Iowa State University Direct Sampling L-Band Digital Radiometer (2006)

This paper describes a polarimetric-capable L-band radiometer that has been built for Iowa State University (ISU) by The University of Michigan. It is a 'direct sampling digital radiometer' (DSDR), in which most of the operations are performed digitally and mixer stages are eliminated. The system is to be used for soil moisture retrieval studies. It could provide supportive data for future L-band missions and is reconfigurable for radio frequency interference (RFI) mitigation purposes
Modulatory role of D-1 and D-2 dopamine receptor subtypes in nociception in mice (1993)

The role of D-1 and D-2 dopamine (DA) receptors in nociception in naive as well as reserpinized mice and the modulation of the nociceptive action of morphine or naloxone by the selective D-1 and D-2 DA agonists, was investigated in mice. The D-2 DA agonists, B-HT 920 and bromocriptine produced an anti-nociceptive effect in naive mice and reversed the hyperalgesic effect of reserpine (2 mg/kg, 4 h prior) pre-treatment. The D-1 DA agonist, SKF 38393 (5 mg/kg) failed to alter the nociceptive responsiveness of naive and reserpinized mice. Apomorphine, a mixed D-1/D-2 DA agonist, produced significant analgesia in naive mice and also reversed reserpine-induced hyperalgesia. SKF 38393 (5 mg/kg) enhanced the anti-nociceptive effect of B-HT 920 (0.1 mg/kg) in naive and reserpine-pre-treated mice. The anti-nociceptive response of morphine (5 mg/kg) was enhanced by B-HT 920 while SKF 38393 reduced the same. Apomorphine (0.5 mg/kg) or the combination of B-HT 920 (0.1 mg/kg) and SKF 38393 (5 mg/kg) failed to enhance the anti-nociceptive effect of morphine. Reserpine (2 mg/kg, 4 h prior) pre-treatment significantly reduced the anti-nociceptive effect of morphine. Similarly, the hyperalgesic action of naloxone (20 mg/kg) was reversed by B-HT 920, bromocriptine and apomorphine but not by SKF 38393. The reversal of the hyperalgesic action of naloxone by B-HT 920 was blocked by pre-treatment with haloperidol (0.5 mg/kg) and sulpiride (100 mg/kg). SKF 38393 (5 mg/kg) failed to potentiate the reversal action of B-HT 920 against naloxone. These data suggest a predominant role of D-2 DA receptors in anti-nociception and the possibility of the existence of an interlink between the DAergic and opioid systems.
Phosphorylation and activation of transforming growth factor beta (TGF-[beta]) receptor kinases (1996)

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1996.
0.25 &amp;#181;m CMOS technology using P<sup>+</sup>polysilicon gate PMOSFET (1987)

A 0.25 µm-channel CMOS Technology, in addition to a latchup-free 0.25 µm isolation technique, has been developed, using p <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">+</sup> poly-Si gate pMOSFET. The p <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">+</sup> poly-Si gate pMOSFET with shallow source/drain junctions, which has symmetric impurity profile to an n <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">+</sup> poly-Si gate nMOSFET, is optimized by using a low energy BF <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">+</sup> implant, combined with a low temperature furnace annealing, followed by a rapid thermal annealing. A short channel effect for both nMOSFET and pMOSFET is reduced, by achieving the shallow junctions and thin gate oxide. Power supply voltage must be reduced to 3V or less in order to maintain n-channel device reliability.
Intrinsic physicochemical profile of marketed antibody-based biotherapeutics (2021)

Feeding biopharma pipelines with biotherapeutic candidates that possess desirable developability profiles can help improve the productivity of biologic drug discovery and development. Here, we have derived an in silico profile by analyzing computed physicochemical descriptors for the variable regions (Fv) found in 77 marketed antibody-based biotherapeutics. Fv regions of these biotherapeutics demonstrate significant diversities in their germlines, complementarity determining region loop lengths, hydrophobicity, and charge distributions. Furthermore, an analysis of 24 physicochemical descriptors, calculated using homology-based molecular models, has yielded five nonredundant descriptors whose distributions represent stability, isoelectric point, and molecular surface characteristics of their Fv regions. Fv regions of candidates from our internal discovery campaigns, human next-generation sequencing repertoires, and those in clinical-stages (CST) were assessed for similarity with the physicochemical profile derived here. The Fv regions in 33% of CST antibodies show physicochemical properties that are dissimilar to currently marketed biotherapeutics. In comparison, physicochemical characteristics of ∼29% of the Fv regions in human antibodies and ∼27% of our internal hits deviated significantly from those of marketed biotherapeutics. The early availability of this information can help guide hit selection, lead identification, and optimization of biotherapeutic candidates. Insights from this work can also help support portfolio risk assessment, in-licensing, and biopharma collaborations.
Effect of NADPH oxidase 1 and 4 blockade in activated human retinal endothelial cells (2018)

Our findings in experiments on activated human retinal endothelial cells provide translational corroboration of studies in experimental models of retinal vasculopathy and support the therapeutic application of Nox4 inhibition by GKT136901 and GKT137831 in patients with retinal vascular diseases.
The Investigation Of Suitability Of Abradable Seal Materials For Application In Centrifugal Compressors And Steam Turbines. (1991)

He is responsible fo r the metallurgical and weld ing
Prognostic effect of ultra-early microscopic clip operation in treating elderly patients with ruptured intracranial aneurysms (2017)

Objective
To analyze the prognostic effect of ultra-early microscopic clip operation in treating the elderly patients with ruptured intracranial aneurysms.


Methods
A total of 130 elderly patients with ruptured intracranial aneurysms were selected in the Department of Neurosurgery, Weifang Brain Hospital from September 2011 to September 2016, and they were divided into ultra-early group (received microscopic clip operation within 1 day after onset, n=64), early group (received microscopic clip operation within 1 day to 3 days after onset, n= 42) and middle-late group groups (received microscopic clip operation after 3 days of onset, n=24) according to operation opportunity. All of the patients were followed up for 3 months, prognostic effect and incidence of complications were compared among the three groups.


Results
The prognostic effect of ultra-early group was statistically significantly better than that of early group (χ2=4.137) and middle-late group (χ2=4.043) , respectively (P 0. 05). In the three groups, the rate of hydrocephalus in ultra-early group was significantly lower than that of early group (χ2=4.705) and middle-late group (χ2=8.282), the difference was statistically significant (P 0.05). There were no statistically significant in the three groups in the incidence of rehaemorrhagia and postoperative cerebral infarction (P>0.05).


Conclusion
Ultra-early microscopic clip operation has good prognostic effect and can reduce the incidence of hydrocephalus in treating the elderly patients.


Key words: 
Intracranial aneurysm; Prognosis; Ultra-early operation
120- and 160-kDa Receptors for Endogenous Mitogenic Peptide, Phytosulfokine-α, in Rice Plasma Membranes (2000)

Plant cells in culture secrete a sulfated peptide named phytosulfokine-alpha (PSK-alpha), and this peptide induces the cell division and/or cell differentiation by means of specific high and low affinity receptors. Putative receptor proteins for this autocrine type growth factor were identified by photoaffinity labeling of plasma membrane fractions derived from rice suspension cells. Incubation of membranes with a photoactivable (125)I-labeled PSK-alpha analog, [N(epsilon)-(4-azidosalicyl)Lys(5)]PSK-alpha (AS-PSK-alpha), followed by UV irradiation resulted in specific labeling of 120- and 160-kDa bands in SDS-polyacrylamide gel electrophoresis. The labeling of both bands was completely inhibited by unlabeled PSK-alpha and partially decreased by PSK-alpha analogs possessing moderate binding activities. In contrast, PSK-alpha analogs that have no biological activity showed no competition for (125)I-AS-PSK-alpha binding, confirming the specificity of binding proteins. Analysis of the affinity of (125)I incorporation into the protein by ligand saturation experiments gave apparent K(d) values of 5.0 nm for the 120-kDa band and 5.4 nm for the 160-kDa band, suggesting that both proteins correspond to the high affinity binding site. Treatment of (125)I-AS-PSK-alpha cross-linked proteins with peptide N-glycosidase F demonstrated that both proteins contained approximately 10 kDa of N-linked oligosaccharides. Specific cross-linking of (125)I-AS-PSK-alpha was also observed by using plasma membranes derived from carrot and tobacco cells, indicating the widespread occurrence of the binding proteins. Together, these data suggest that the 120- and 160-kDa proteins are PSK-alpha receptors that mediate the biological activities of PSK-alpha.
Analog and mixed-signal benchmark circuits-first release (2002)

The IEEE Mixed-Signal Technical Activity Committee is developing a common set of benchmark circuits for use in researching and evaluating analog fault modeling, test generation, design-for-test, and built-in self-test methodologies. The first release circuits are based on MITEL Semiconductor's 1.5 /spl mu/m and 1.2 /spl mu/m CMOS technologies and they will allow engineers and researchers working in analog and mixed-signal testing to compare test results as is done in the digital domain. This paper presents a set of typical circuits described by netlists in HSPICE format. Schematic diagrams, simulation results and measured results, if available, are provided together with layout and a typical test environment. The full details are available on the web page dedicated to analog and mixed-signal benchmarks.