gebhart/patrepeval huggingface dataset:
Carbon nanotube and its applications in textile industry – A review (2018)

One of the major components of nanotechnology is Carbon nanotube (CNT) that can have a length-to-diameter ratio more than 1,000,000. They are used in several fields in material science, due to their exceptional electrical, mechanical, and thermal properties, which are anisotropic. Different techniques have been developed to produce CNT. They have good potential for applications in various technological areas such as nanoelectronic, biotechnology, material science, polymer, composite, and textile industries. In this paper, recent researches on application of CNT in textile industry are reviewed. Treatment of textiles with CNT leads to the production of a wide variety of conductive textiles with different electrical properties. The wear performances of fabrics apply with CNT to open the potentiality of producing composite materials for conventional and innovative applications, ranging from conventional apparel and sportswear to protective clothing, heating equipment, automotive textiles, building covering, geo-textiles, biomedical textiles, etc.
A Gly1127Ser mutation in an EGF-like domain of the fibrillin-1 gene is a risk factor for ascending aortic aneurysm and dissection. (1995)

Ascending aortic disease, ranging from mild aortic root enlargement to aneurysm and/or dissection, has been identified in 10 individuals of a kindred, none of whom had classical Marfan syndrome (MFS). Single-strand conformation analysis of the entire fibrillin-1 (FBN1) cDNA of an affected family member revealed a G-to-A transition at nucleotide 3379, predicting a Gly1127Ser substitution. The glycine in this position is highly conserved in EGF-like domains of FBN1 and other proteins. This mutation was present in 9 of 10 affected family members and in 1 young unaffected member but was not found in other unaffected members, in 168 chromosomes from normal controls, and in 188 chromosomes from other individuals with MFS or related phenotypes. FBN1 intragenic marker haplotypes ruled out the possibility that the other allele played a significant role in modulating the phenotype in this family. Pulse-chase studies revealed normal fibrillin synthesis but reduced fibrillin deposition into the extracellular matrix in cultured fibroblasts from a Gly1127Ser carrier. We postulate that the Gly1127Ser FBN1 mutation is responsible for reduced matrix deposition. We suggest that mutations such as this one may disrupt EGF-like domain folding less drastically than do substitutions of cysteine or of other amino acids important for calcium-binding that cause classical MFS. The Gly1127Ser mutation, therefore, produces a mild form of autosomal dominantly inherited weakness of elastic tissue, which predisposes to ascending aortic aneurysm and dissection later in life.
Antigenic complexity of <i>Treponema pallidum</i>: antigenicity and surface localization of major polypeptides. (1984)

The protein structure of Treponema pallidum was characterized by two-dimensional electrophoresis (2DE), consisting of isoelectric focusing (IEF, pH 5 to 7) in the first dimension and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) in the second dimension. Up to 85 major polypeptide species could be detected in the organisms in 2DE gels by Coomassie Blue staining. The antigenicity of the individual polypeptides was determined by transferring the 2DE pattern to nitrocellulose paper and utilizing a sensitive immunoperoxidase procedure to demonstrate the reactivity of immunoglobulins in sera obtained from rabbits infected intratesticularly at least 6 mo previously. The infected rabbit serum reacted with virtually every major polypeptide detectable by protein staining techniques, indicating that infected rabbits produce antibodies against nearly all major T. pallidum proteins at the time when the animals exhibit systemic resistance to reinfection. Surface radioiodination of freshly purified T. pallidum by an Iodogen procedure yielded preferential labeling of a major polypeptide with an apparent m.w. of 39,000. The results of this study indicate that the antigenic complexity of T. pallidum is much greater than described previously. The 39-kd polypeptide appears to be a major surface constituent of T. pallidum and as such may play an important role in the induction of immunity to syphilis.
Efficient hardware architecture of recursive Karatsuba-Ofman multiplier (2008)

The finite Field multiplication is the basic operation in all cryptographic applications. It can be performed by using Serial, Booth, Montgomery and Karatsuba-Ofman’s divide-and-conquer technique. The Karatsuba-Ofman multiplier replaces a multiplication by three ones of half-length operands which are performed in parallel. The implementation of Karatsuba-Ofman multiplier has been made both in sequential and parallel architectures. In order to improve the performance’s architectures over GF (2 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">m</sup> ), we propose a new Sequential/Parallel architectures of Recursive Karatsuba-Ofman multiplier. In this paper, two Sequential/Parallel architectures are presented, developed and implemented on the Spartan 3 FPGA platform. Area and low Delay computation of the proposed architectures are improved. Mathematical Performances models (Area (n), Delay (n)) for large number (n) are elaborated for our proposed architectures. They can be established in order to expect the appropriate multiplier for the cryptographic applications.
Early Prediction of Cardiac Arrest (Code Blue) using Electronic Medical Records (2015)

Code Blue is an emergency code used in hospitals to indicate when a patient goes into cardiac arrest and needs resuscitation. When Code Blue is called, an on-call medical team staffed by physicians and nurses is paged and rushes in to try to save the patient's life. It is an intense, chaotic, and resource-intensive process, and despite the considerable effort, survival rates are still less than 20% [4]. Research indicates that patients actually start showing clinical signs of deterioration some time before going into cardiac arrest [1][2[][3], making early prediction, and possibly intervention, feasible. In this paper, we describe our work, in partnership with NorthShore University HealthSystem, that preemptively flags patients who are likely to go into cardiac arrest, using signals extracted from demographic information, hospitalization history, vitals and laboratory measurements in patient-level electronic medical records. We find that early prediction of Code Blue is possible and when compared with state of the art existing method used by hospitals (MEWS - Modified Early Warning Score)[4], our methods perform significantly better. Based on these results, this system is now being considered for deployment in hospital settings.
Rapid Adaptation of Cardiac Ryanodine Receptors: Modulation by Mg <sup>2+</sup> and Phosphorylation (1995)

Channel adaptation is a fundamental feature of sarcoplasmic reticulum calcium release channels (called ryanodine receptors, RyRs). It permits successive increases in the intracellular concentration of calcium (Ca2+) to repeatedly but transiently activate channels. Adaptation of RyRs in the absence of magnesium (Mg2+) and adenosine triphosphate is an extremely slow process (taking seconds). Photorelease of Ca2+ from nitrophenyl-EGTA, a photolabile Ca2+ chelator, demonstrated that RyR adaptation is rapid (milliseconds) in canine heart muscle when physiological Mg2+ concentrations are present. Phosphorylation of the RyR by protein kinase A increased the responsiveness of the channel to Ca2+ and accelerated the kinetics of adaptation. These properties of the RyR from heart may also be relevant to other cells in which multiple agonist-dependent triggering events regulate cellular functions.
Hierarchical Hyperlink Prediction for the WWW (2016)

The hyperlink prediction task, that of proposing new links between webpages, can be used to improve search engines, expand the visibility of web pages, and increase the connectivity and navigability of the web. Hyperlink prediction is typically performed on webgraphs composed by thousands or millions of vertices, where on average each webpage contains less than fifty links. Algorithms processing graphs so large and sparse require to be both scalable and precise, a challenging combination. Similarity-based algorithms are among the most scalable solutions within the link prediction field, due to their parallel nature and computational simplicity. These algorithms independently explore the nearby topological features of every missing link from the graph in order to determine its likelihood. Unfortunately, the precision of similarity-based algorithms is limited, which has prevented their broad application so far. In this work we explore the performance of similarity-based algorithms for the particular problem of hyperlink prediction on large webgraphs, and propose a novel method which assumes the existence of hierarchical properties. We evaluate this new approach on several webgraphs and compare its performance with that of the current best similarity-based algorithms. Its remarkable performance leads us to argue on the applicability of the proposal, identifying several use cases of hyperlink prediction. We also describes the approach we took for the computation of large-scale graphs from the perspective of high-performance computing, providing details on the implementation and parallelization of code.
Relief of continuous chronic pain by intraspinal narcotics infusion via an implanted reservoir (1983)

Ten patients with intractable pain (five cancer and five nonmalignant) were treated with continuous intraspinal morphine delivered by an implanted continuous infusion system. Both patient groups were evaluated and compared using an identical battery of psychometric examinations administered before and 12 weeks after therapy. The cancer-pain group reported significant reduction in pain on serial visual pain analogue scales at 12 weeks compared with no change in the nonmalignant-pain group reports despite a much lower baseline report in the cancer group. Both groups of patients reduced their oral narcotic requirement significantly during continuous intraspinal morphine infusion. While the cancer patients took more oral narcotic at baseline, at 12 weeks no difference existed in oral intake between the two groups. Both groups required significant serial increases in infused morphine, indicating that spinal opiate receptor tolerance occurs. The results of this study confirm the sustained analgesic efficacy reported earlier in cancer-related pain syndromes, thus supporting further cautious expansion of this therapy within the cancer-related pain population. In contrast, a poor response was seen in the nonmalignant-pain group, consistent with the unsatisfactory responses to many potentially analgetic approaches to chronic nonmalignant pain. We are thus discouraged from further use of this therapy in the patient with chronic nonmalignant pain. (<i>JAMA</i>1983;250:2336-2339)
Page segmentation using document model (2002)

Transforming a paper document to its electronic version in a form suitable for efficient storage, retrieval and interpretation continues to be a challenging problem. An efficient document model is necessary to solve this problem. Document modeling involves techniques of thresholding, skew detection, geometric layout analysis and logical layout analysis. The derived model can then be used in document storage and retrieval. We use the traditional bottom-up approach based on the connected component extraction to efficiently implement page segmentation and region identification. A new document model which preserves top-down generation information is proposed based on which a document is logically represented for interactive editing, storage, retrieval, transfer and logical analysis.
Confirmatory Test of a Turnover Model Utilizing Multiple Data Sources (1991)

In recent years, there have been several confirmatory tests of turnover models, based almost exclusively on subject self-reports for all but the measurement of turnover itself. A test of a subset of the Mobley, Griffeth, Hand, and Meglino (1979) model was conducted using data from three sources. It was proposed that autonomy, workload, constraints, role ambiguity, and interper- sonal conflict (assessed by supervisor reports) would lead to job satisfaction (assessed by subject reports), which would lead to intention of quitting (as- sessed by subject reports), which would lead to turnover (from organization records). A trimmed version of the model (with role ambiguity and interper- sonal conflict deleted) yielded good overall fit, but job conditions accounted for a very small amount of job satisfaction variance, and workload related in a direction opposite to predictions.
Phase I clinical and pharmacokinetic study of topotecan administered by a 24-hour continuous infusion. (1995)

The recommended dose for phase II studies is 8.4 mg/m2 when administered as a 24-hour infusion, which is well tolerated. Further studies will be necessary to account for the putative nonlinear behavior of the drug.
N-Terminal Derivatization-Assisted Identification of Individual Amino Acids Using a Biological Nanopore Sensor (2020)

Nanopore technology has been employed as a powerful tool for DNA sequencing and analysis. To extend this method to peptide sequencing, a necessary step is to profile individual amino acids (AAs) through their nanopore stochastic signals, which remains a great challenge because of the low signal-to-noise ratio and unpredictable conformational changes of AAs during their translocation through nanopores. We showed that the combination of an N-terminal derivatization strategy of AAs with nanopore technology could lead to effective <i>in situ</i> differentiation of AAs. Four different derivatization reactions have been tested with five selected AAs: Ala, Phe, Tyr, His, and Asp. Using an α-hemolysin nanopore, we demonstrated the feasibility of derivatization-assisted identification of AAs regardless of their charge composition and polarity. The method was further applied to discriminate each individual AA in testing data sets using their established nanopore profiles from training data sets. We envision that this proof-of-concept study will not only pave a way for identification of individual AAs but also lead to future applications in protein/peptide sequencing using the nanopore technology.
Magnetic properties and anisotropy of CoCr thin films for perpendicular recording (1988)

CoCr thin films, 50 Å to 1 μm thick, have been rf sputtered onto a number of different substrates. These films have been studied for their nucleation, microstructure, magnetic properties, and anisotropy. It has been observed that at lower thicknesses, the grains are extremely small (200 Å at 0.1 μm) but cover the entire substrate surface quite uniformly. Below the thickness of 100 Å, the coercivity Hc approaches zero very rapidly and the film approaches superparamagnetic state. As the film thickness is increased, the grains get larger (800 Å at 1 μm) and the coercivity of the film increases. The Δθ50 value for the (0002) x-ray peak reached 2°. The grain size clearly dominates the coercivity of these films. The effective anisotropy constants increased from 1.31 to 3.16×105 ergs/cm3 for the above thickness range. Estimates of the magnetocrystalline anisotropy field are determined from a uniform thin-film model and a model that accounts for the columnar grains. When the circular magnetic columns are in contact, the shape anisotropy field is 5% lower than the uniform thin-film approximation. When the magnetic radius is 80% of the grain radius, then the shape anisotropy field is 34% lower.
Synthesis of 1,3,5(10)-Estratriene-3,16β,17α-triol<sup>1</sup> (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of 1,3,5(10)-Estratriene-3,16β,17α-triol1JACK FISHMAN and WARREN R. BIGGERSTAFFCite this: J. Org. Chem. 1958, 23, 8, 1190–1192Publication Date (Print):August 1, 1958Publication History Published online1 May 2002Published inissue 1 August 1958https://pubs.acs.org/doi/10.1021/jo01102a028https://doi.org/10.1021/jo01102a028research-articleACS PublicationsRequest reuse permissionsArticle Views123Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Homocysteine as a Predictive Factor for Hip Fracture in Older Persons (2004)

These findings suggest that the homocysteine concentration, which is easily modifiable by means of dietary intervention, is an important risk factor for hip fracture in older persons.
HIV-1-infected Blood Mononuclear Cells Form an Integrin- and Agrin-dependent Viral Synapse to Induce Efficient HIV-1 Transcytosis across Epithelial Cell Monolayer (2005)

The heparan sulfate proteoglycan agrin and adhesion molecules are key players in the formation of neuronal and immune synapses that evolved for efficient communication at the sites of cell-cell contact. Transcytosis of infectious virus across epithelial cells upon contact between HIV-1-infected cells and the mucosal pole of the epithelial cells is one mechanism for HIV-1 entry at mucosal sites. In contrast, transcytosis of cell-free HIV-1 is not efficient. A synapse between HIV-1-infected cells and the mucosal epithelial surface that resembles neuronal and immune synapses is visualized by electron microscopy. We have termed this the "viral synapse." Similarities of the viral synapse also extend to the functional level. HIV-1-infected cell-induced transcytosis depends on RGD-dependent integrins and efficient cell-free virus transcytosis is inducible upon RGD-dependent integrin cross-linking. Agrin appears differentially expressed at the apical epithelial surface and acts as an HIV-1 attachment receptor. Envelope glycoprotein subunit gp41 binds specifically to agrin, reinforcing the interaction of gp41 to its epithelial receptor galactosyl ceramide.
Accurate shape-based 6-DoF pose estimation of single-colored objects (2009)

The problem of accurate 6-DoF pose estimation of 3D objects based on their shape has so far been solved only for specific object geometries. Edge-based recognition and tracking methods rely on the extraction of straight line segments or other primitives. Straight-forward extensions of 2D approaches are potentially more general, but assume a limited range of possible view angles. The general problem is that a 3D object can potentially produce completely different 2D projections depending on the view angle. One way to tackle this problem is to use canonical views. However, accurate shape-based 6-DoF pose estimation requires more information than matching of canonical views can provide. In this paper, we present a novel approach to 6-DoF pose estimation of single-colored objects based on their shape. Our approach combines stereo triangulation with matching against a high-resolution view set of the object, each view having associated orientation information. The errors that arise from separating the position and orientation computation in first place are corrected by a subsequent correction procedure based on online 3D model projection. The proposed approach can estimate the pose of a single object within 20 ms using conventional hardware.
CO Chemisorption on the [111] and [100] Oriented Surfaces of the CoPt{sub 3} Alloy (1989)

In a previous study, it was shown that surfaces of both the [111] and [100] oriented single crystals of CoPt 3 have a .. sandwich .. structure having an outermost atomic 1 ayer that is essentially pure Pt and a second layer enriched in Co (with respect to the bulk).In the
"HOOK CATHETER," TECHNIQUE FOR TRANSFEMORAL REMOVAL OF FOREIGN BODY FROM RIGHT SIDE OF THE HEART (1970)

"HOOK CATHETER," TECHNIQUE FOR TRANSFEMORAL REMOVAL OF FOREIGN BODY FROM RIGHT SIDE OF THE HEARTPLINIO ROSSI, M.D.Audio Available | Share
The discovery of a novel prototype small molecule TLR7 agonist for the treatment of hepatitis C virus infection (2010)

A series of heterocycle analogues of an adenine template were explored for TLR7 agonist potency and pharmacokinetics. One compound was identified with an excellent pharmacokinetic, in vitro potency and in vivo interferon induction profile in a mouse model, and was selected for further pre-clinical evaluation as a potential treatment for hepatitis C viral infection.
Advanced Limited Feedback Designs for FD-MIMO Using Uniform Planar Arrays (2015)

Massive multiple-input multiple-output (MIMO) with uniform planar arrays (UPAs), which is often referred to as full-dimension (FD) MIMO, is being strongly considered for future wireless communication standards. FD-MIMO can control transmit and receive beams in both the horizontal and vertical domains and fully exploit the large number of antennas of massive MIMO. It is widely accepted that Kronecker-product codebooks using a discrete Fourier transform (DFT) structure are suitable to quantize the downlink channel at the user for FD-MIMO systems relying on frequency division duplexing (FDD). In this paper, we numerically study the characteristics of FD-MIMO channels using a three-dimensional (3D) channel model that captures realistic channel properties. Based on the study, we identify a limitation of conventional Kronecker-product codebooks and propose advanced channel quantization techniques that can further improve channel quantization quality.
Improving the Energy-Efficiency of GPS Based Location Sensing Smartphone Applications (2012)

Smartphones with an embedded GPS sensor are being increasingly used for location determination to enable Location based services (LBS) deliver location context pervasive computing services such as maps and navigation. Although a Smartphone GPS provides adequate accuracy, it has limitations such as high energy consumption and is unavailable in locations with an obscured view of GPS satellites. Use of alternate location sensors such as Wi-Fi and GSM can be used to augment GPS and to alleviate these GPS limitations, but they can increase the average localization error. The novelty of our contribution is twofold. First we present an accelerometer based architecture that reduces GPS energy-consumption without compromising on either the location accuracy or sampling rate. Evaluation of our system shows energy-savings of up to 27% in typical circumstances. Second, as a user's mobility state is complex we also propose a method to not only detect that a user is non-stationary but also classify a representative set of mobility states.
Disintegration of colonic epithelial tight junction in uremia: a likely cause of CKD-associated inflammation (2011)

The study revealed, for the first time, that uremia results in depletion of the key protein constituents of the colonic tight junction, a phenomenon which can account for the impaired intestinal barrier function and contribute to the systemic inflammation in CKD.