gebhart/patrepeval huggingface dataset:
[The role of endogenous glutathione in the action of sulfur-containing radio-protectors]. (1984)

In experiments on Ehrlich ascite tumor cells, the dependence of the radioprotective effect of beta-mercaptoethylamine and beta-mercaptopropionylglycine on the initial level of endogenous glutathione was studied. A varying degree of N-ethylmaleimide induced decrease of SH-glutathione content in the cells led to either easing or elimination of the radioprotective effect of the agents under study.
Fuzzy Basis Function Networks of Hierarchical Structure for Modeling Manufacturing Processes (1998)

Abstract A framework for modeling complex manufacturing processes using fuzzy neural networks is presented with a novel training algorithm. In this study, fuzzy basis function networks (FBFN) which are similar in structure to radial basis function networks are adopted. A hierarchical structure which consists of FBFNs is proposed to construct comprehensive models of the complex processes. The modeling scheme provides valuable advantages over the conventional approaches. A new adaptive least-squares (ALS) algorithm, based on the least-squares method and genetic algorithm (GA), is proposed for autonomous learning and construction of FBFNs. It adds significant fuzzy basis functions (FBF) at each iteration depending on error reduction measures while searching for the best nonlinear parameters of the networks using GA. The ALS algorithm realizes a hybrid structure-parameter learning without any human intervention. Simulation studies with grinding processes are shown to demonstrate that the proposed modeling framework with the training algorithm is a promising approach to modeling complex manufacturing processes.
Soviet Economics - * S. N. Prokopovicz: Russlands Volkswirtschaft unter den Sowjets. (Zürich: Europa Verlag, 1944. Pp. 459. $5.50.) (1947)

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High Voltage LDMOS Transistors utilizing a Triple Well Architecture (2007)

We present the integration, device fabrication as well as a reliability analysis of 36 V drain extended CMOS transistors into a 0.35 CMOS baseline technology by utilizing the existing implants and adding 2 additional masking layers. Breakdown voltages >70 V for DENMOS and >60 V for DEPMOS are achieved employing the drain extended device structure. These high breakdown voltages can only be achieved because of careful junction design.
ION ASSOCIATION. V. DISSOCIATION CONSTANTS FOR COMPLEXES OF CITRATE WITH SODIUM, POTASSIUM, CALCIUM, AND MAGNESIUM IONS<sup>1</sup> (1961)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTION ASSOCIATION. V. DISSOCIATION CONSTANTS FOR COMPLEXES OF CITRATE WITH SODIUM, POTASSIUM, CALCIUM, AND MAGNESIUM IONS1Mackenzie WalserCite this: J. Phys. Chem. 1961, 65, 1, 159–161Publication Date (Print):January 1, 1961Publication History Published online1 May 2002Published inissue 1 January 1961https://pubs.acs.org/doi/10.1021/j100819a045https://doi.org/10.1021/j100819a045research-articleACS PublicationsRequest reuse permissionsArticle Views756Altmetric-Citations43LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Hypoxia causes glycogenolysis without an increase in percent phosphorylase a in rat skeletal muscle (1992)

Stimulation of skeletal muscle to contract activates phosphorylase b-to-a conversion and glycogenolysis. Despite reversal of the increase in percentage of phosphorylase a after a few minutes, continued glycogen breakdown can occur during strenuous exercise. Hypoxia causes sustained glycogenolysis in skeletal muscle without an increase in percentage of phosphorylase a. We used this model to obtain insights regarding how glycogenolysis is mediated in the absence of an increase in percentage of phosphorylase a. Hypoxia caused a 70% decrease in glycogen in epitrochlearis muscles during an 80-min incubation despite no increase in percentage of phosphorylase a above the basal level of approximately 10%. Muscle Pi concentration increased from 3.8 to 8.6 mumol/g muscle after 5 min and 15.7 mumol/g after 20 min. AMP concentration doubled, attaining a steady state of 0.23 mumol/g in 5 min. Incubation of oxygenated muscles with 0.1 microM epinephrine induced an approximately sixfold increase in percentage of phosphorylase a but resulted in minimal glycogenolysis. Muscle Pi concentration was not altered by epinephrine. Despite no increase in percentage of phosphorylase a, hypoxia resulted in a fivefold greater depletion of glycogen over 20 min than did epinephrine. To evaluate the role of phosphorylase b, muscles were loaded with 2-deoxyglucose 6-phosphate, which inhibits phosphorylase b. The rate of glycogenolysis during 60 min of hypoxia was reduced by only approximately 14% in 2-deoxyglucose 6-phosphate-loaded muscles.(ABSTRACT TRUNCATED AT 250 WORDS)
Estimation of In-situ Stress State for NC Clays Using PCPT Results (2010)

In this study, a method for estimating the in-situ stress state of NC clays using piezocone penetration test (PCPT) results is proposed. The proposed method is based on a correlation between the PCPT results and strength increment ratio. According to proposed method, no additional testing procedure for collecting undisturbed soil sample is required, which can reduce overall testing cost. To verify this method various analytical solutions were adopted and used. Measured result and predicted result are compared with each other. The verification sites consist of a variety of soil conditions. From the comparison, it is seen that predicted value of effective strcss using the proposed method match well those from measured results.
Ouabain‐resistant non‐small‐cell lung‐cancer CELL LINE SHOWS COLLATERAL SENSITIVITY TO <i>cis</i>‐diamminedichloroplatinum(II) (CDDP) (1994)

We have reported that the cellular uptake of cis-diamminedichloroplatinum(II) (CDDP) was inhibited by an Na+,K(+)-adenosine triphosphatase (ATPase) inhibitor, ouabain, in a human non-small-cell lung-cancer cell line, PC-14, but not in its CDDP-resistant cell line, PC-14/CDDP. [3H]Ouabain binding of PC-14/CDDP was about 50% lower than that of PC-14. Accordingly, we speculated that a decrease in Na+,K(+)-ATPase activity in PC-14/CDDP might contribute to the decrease in cellular CDDP accumulation. To clarify the relationship between the activity or expression of Na+,K(+)-ATPase and cellular CDDP accumulation, we established an ouabain-resistant non-small-cell lung-cancer cell line (PC-14/OB300), which showed 1.9-fold resistance to the cytotoxicity of ouabain. Interestingly, this cell line was 4.2-fold more sensitive to CDDP than PC-14. The accumulation of CDDP in PC-14/OB300 was increased to 2.7-fold that in PC-14. This elevation of CDDP accumulation was not considered to be caused by increased passive diffusion, because the accumulation of CDDP in PC-14/OB300 was also inhibited by ouabain compared to PC-14. As one of the indices of Na+,K(+)-ATPase activity, we determined cellular 86Rb+ influx rates. The 86Rb+ influx rate was 1.5-fold higher in PC-14/OB300 and fell to 0.7-fold in PC-14/CDDP compared with PC-14. The mRNA expression of Na+,K(+)-ATPase was increased in PC-14/OB300 and decreased in PC-14/CDDP. There was no difference in cellular [3H]ouabain binding between PC-14/OB300 and PC-14. It is possible that Na+,K(+)-ATPase of PC-14/OB300 has a different affinity for ouabain from that of PC-14. Our results suggest that the enzyme activity or the level of expression of Na+,K(+)-ATPase may contribute to the cellular uptake of CDDP and determine the sensitivity to CDDP.
In-flight Melting of Granulated Powders in Thermal Plasmas for Glass Production (2007)

The innovative in-flight glass melting technology with thermal plasmas was developed for the purpose of energy conservation and environmental protection for glass production. Modeling and experiments of induction thermal plasmas have been performed to investigate the melting behavior of granulated powders injected into thermal plasmas. The thermofluid fields were obtained by solving two-dimensional modeling for argon plasmas under atmospheric pressure. Results show the strong influence of carrier gas flow rate on the melting behavior. With flow rate increasing, the particle size and temperature of glass transition and softening decrease, whereas the amount of unreacted Si0 2 increases because of lower plasma temperature and shorter residence time. The experimental results are consistent with the model, which gives valuable practical guidelines in optimizing the process parameters and controlling the product characteristics.
The inner most loop iteration counter (2015)

The most efficient branch predictors proposed in academic literature exploit both global branch history and local branch history. However, local history branch predictor components introduce major design challenges, particularly for the management of speculative histories. Therefore, most effective hardware designs use only global history components and very limited forms of local histories such as a loop predictor.
Multiobjective service restoration of distribution systems using fuzzy cause-effect networks (2003)

This paper proposes the use of a fuzzy cause-effect (FCE) network to achieve the multiobjective service restoration of distribution systems. Service restoration is a complicated combinatorial optimization problem that often has a great number of candidate solutions to be evaluated by the operators. To tackle the problem of service restoration with multiple objectives, the weighted sum strategy is employed to convert these objectives into a single objective function by giving relative weighting values. The weighting factor of each objective is assessed via the analytical hierarchy process (AHP) approach. Since the operators' needs and heuristic rules are often expressed in imprecise linguistic terms, the FCE networks are then built to represent the related knowledge and inference scheme regarding the task of restoration. The proposed FCE networks were practically tested on a typical distribution system of the Taiwan Power Company (TPC). The flexibility and effectiveness of the FCE networks have validated it for use as decision support in restoration scheduling of distribution systems.
PSK versus QAM for iterative decoding of bit-interleaved coded modulation (2005)

Bit-interleaved coded modulation with iterative decoding (BICM-ID) is a transmission scheme with excellent performance on fading channels. The mapping of the bit patterns to the elements of the signal constellation set (SCS) is the key design element of BICM-ID, especially regarding the asymptotic performance of the BER. We demonstrate that SCSes of PSK (phase shift keying) with optimum bit pattern assignment are significantly superior in the asymptotic error-floor region to the respective square QAM (quadrature amplitude modulation) SCSes. When modifying the PSK SCSes to non-regular SCSes, performance gains of more than 1 dB are realizable in the case of 4 bits-per-channel symbols. The achievable gains are theoretically determined and analyzed, and verified by simulations.
Expression of cellular genes in HPV16‐immortalized and cigarette smoke condensate‐transformed human endocervical cells (1997)

We studied the molecular mechanism of successive multistep cervical carcinogenic progression with our previously established in vitro model system. This system was composed of primary human endocervical cells (HEN), two lines of HEN immortalized by HPV16 and their counterparts subsequently malignantly transformed by cigarette smoke condensate (CSC). The expression was examined of diverse cellular genes associated with oncogenesis and senescence, especially for cervical cancer. Consistent results were seen for the pairs of immortalized and malignantly transformed lines. Immortalization of HEN by HPV16 resulted in enhanced expression of H-ras, c-myc, B-myb, p53, p16INK4 and PCNA mRNA; enhanced expression of p16 and PCNA proteins; decreased expression of WAF1/p21/Cip1/Sid1 and fibronectin mRNA; and decreased p53 protein. On the other hand, the CSC-transformed counterparts of HPV16-immortalized cells had up-regulated levels of B-myb, p53 and WAF1 mRNA and p53 protein. Our results indicate that the differential activation or inactivation of multiple cellular genes is important for the immortalization, as well as the transformation, of human cervical cells. Further, we suggest that our in vitro model system is useful for investigating the molecular mechanism of multistep cervical carcinogenesis. J. Cell. Biochem. 66: 309–321, 1997. © 1997 Wiley-Liss, Inc.
A Theoretical Analysis of the Plain-Knitted Structure (1970)

A theoretical analysis was made of the relaxed plain-knitted structure. The analysis differs from previous ones in that no arbitrary geometrical loop shape is assumed and no empirical methods are used. The loop configuration is de rived from consideration of the reaction forces and couples acting within the structure, their magnitude being determined by the yarn displacement necessary for loop interlocking. A minimum-energy structure is shown to exist; this structure is fairly independent of fabric tightness and yarn properties. The actual energy minimum is fairly shallow, so that in practice some difficulty could be expected in obtaining a perfectly relaxed fabric; this would lead to a corresponding spread in experimental values of plain-knitted fabric shape and dimensions. The numerical values of fabric dimensions obtained from the analysis show good agreement with the experimental data reported by other workers.
Analysis of permanent-magnet machine for sensorless control based on high-frequency signal injection (2004)

This paper presents the analysis of a surface-mounted permanent-magnet (SMPM) machine for the sensorless control scheme based on the high-frequency fluctuating voltage signal injection method. A simplified high-frequency model of an SMPM machine in the estimated rotor reference frame is developed and a sensorless rotor position and speed estimation algorithm is described. To support this, the high-frequency impedances of an SMPM machine are analyzed by finite-element analysis (FEA) and compared with measurement results using a pulsewidth-modulation (PWM) inverter system under various injection conditions. The results of the FEA and measurements are coincident with each other with some errors due to the nonlinear behavior of the PWM inverter and the SMPM machine. The analysis results give physical insights into selecting the injection conditions for sensorless operation of the SMPM machine even though adjustments considering nonlinear behaviors of PWM inverters are required in the actual operation for the desired performance. The experimental results of speed and position control using a commercial SMPM machine are presented based on the analysis of the SMPM machine for the sensorless control algorithm.
The study of perpendicular magnetic anisotropy in CoFeB sandwiched by MgO and tantalum layers using polarized neutron reflectometry (2012)

The perpendicular magnetic anisotropy (PMA) in CoFeB sandwiched by MgO and tantalum layers was investigated using anomalous Hall effect and polarized neutron reflectometry. It was found that a large PMA in the CoFeB above MgO layer was related to its low magnetization compared to the case of CoFeB under MgO layer. Using the sensitivity of neutrons to the absorption cross-section of boron, we unambiguously determined the depth profile of the boron distribution and showed that after annealing, most of the boron diffused to form a 2-nm-thick interface layer between the CoFeB and tantalum layers.
Magnetic super-resolution (1995)

Magnetically induced super-resolution (MSR) disks have been proposed to overcome the diffraction limit. This paper reports an MSR disk which has exchange-coupled magnetic double layers. An in-plane magnetization film is used as a readout layer in the magnetic double layers. The MSR disk can be overwritten by a magnetic field modulation recording method. An areal density of 2.2 Gbit/in/sup 2/ was obtained with a currently available optical head having a 680 nm wavelength laser. Besides, the disk had high recorded-data-stability in continuous readout of 5/spl times/10/sup 5/ revolutions with a laser power of 2.5 mW, and it also kept a high signal quality after a continuous erasing test of 2/spl times/10/sup 5/ revolutions with a recording laser power of 6.5 mW.
Very low voltage single drive domain inverted LiNbO_3 integrated electro-optic modulator (2007)

Domain inversion is used in a simple fashion to improve significantly the performance of a waveguide electro-optic modulator in z-cut LiNbO(3). The waveguide arms of the Mach-Zehnder interferometer are placed in opposite domain-oriented regions under the same, narrower and more efficient electrode, so that opposite phase shifts (push-pull effect) can still be achieved despite the arms being subjected to the same electric field. Switching voltages close to 2 V are obtained, which allow 10Gb/s modulation with inexpensive drivers, such as those used for electro-absorption modulators, which deliver driving voltages well below 3V.
Delta ribozyme has the ability to cleave in transan mRNA (1999)

We report here the first demonstration of the cleavage of an mRNA in trans by delta ribozyme derived from the antigenomic version of the human hepatitis delta virus (HDV). We characterized potential delta ribozyme cleavage sites within HDV mRNA sequence (i.e. C/UGN6), using oligonucleotide binding shift assays and ribonuclease H hydrolysis. Ribozymes were synthesized based on the structural data and then tested for their ability to cleave the mRNA. Of the nine ribozymes examined, three specifically cleaved a derivative HDV mRNA. All three active ribozymes gave consistent indications that they cleaved single-stranded regions. Kinetic characterization of the ability of ribozymes to cleave both the full-length mRNA and either wild-type or mutant small model substrate suggests: (i) delta ribozyme has turnovers, that is to say, several mRNA molecules can be successively cleaved by one ribozyme molecule; and (ii) the substrate specificity of delta ribozyme cleavage is not restricted to C/UGN6. Specifically, substrates with a higher guanosine residue content upstream of the cleavage site (i.e. positions -4 to -2) were always cleaved more efficiently than wild-type substrate. This work shows that delta ribozyme constitutes a potential catalytic RNA for further gene-inactivation therapy.
A PNEUMATIC SEISMIC ENERGY SOURCE FOR SHALLOW WATER / MARSH AREAS* (1970)

A bstract Non dynamite seismic energy sources have shown only limited success in difficult shallow‐water or marsh prospect areas, and none have applicability to both environments. Recently, a method has been devised to adapt a marine pneumatic source for operation in abrasive surroundings. A system composed of four of these modified sources together with associated emplacement and retrieval mechanisms has been developed and has proven to be a reliable and efficient seismic energy source for both shallow‐water and marsh applications.
Evaluation of the diagnostic value of the first‐trimester maternal serum high‐sensitivity <scp>C</scp>‐reactive protein level for prediction of pre‐eclampsia (2013)

Hs-CRP measurements during the first trimester of pregnancy are helpful in predicting pre-eclampsia.
Contribution of nitric oxide and prostaglandins to reactive hyperemia in the human forearm (1996)

We investigated the separate and combined contributions of nitric oxide (NO) and vasodilating prostaglandins as mediators of reactive hyperemia in the human forearm. Forearm blood flow (FBF) was measured with venous occlusion plethysmography after 5 min of ischemia. In one protocol (n = 12), measurements were made before and after intra-arterial administration of the NO synthase inhibitor NG-monomethyl-L-arginine (L-NMMA) to one forearm. In a separate protocol (n = 7), measurements were made before and after systemic administration of the cyclooxygenase inhibitor ibuprofen and again after L-NMMA. L-NMMA reduced baseline FBF at rest (2.7 +/- 0.4 to 1.6 +/- 0.2 ml.100 ml-1.min-1; P < 0.05) and had a modest effect on peak forearm vascular conductance and flow (forearm vascular conductance = 31.1 +/- 3.1 vs. 25.7 +/- 2.5 ml.min-1.100 ml forearm-1.100 mmHg of perfusion pressure-1.min-1, P < 0.05; FBF = 26.6 +/- 2.9 vs. 22.8 +/- 2.6 ml.100 ml-1.min-1, P = 0.055). Total excess flow above baseline during reactive hyperemia was unaffected by L-NMMA (14.3 +/- 3.0 vs. 13.1 +/- 2.4 ml/100 ml; P < 0.05). Ibuprofen did not change FBF at rest, reduced peak FBF from 27.6 +/- 1.9 to 20.3 +/- 2.7 ml.100 ml-1.min-1 (P < 0.05), but had no effect on total excess flow above baseline, Infusion of L-NMMA after ibuprofen reduced FBF at rest by 40%, had no effect on peak flow, but reduced total excess flow above baseline from 12.0 +/- 2.5 to 7.6 +/- 1.3 ml/100 ml (P < 0.05). These date demonstrate that NO synthase inhibition has a modest effect on peak vasodilation during reactive hyperemia but plays a minimal role later. Prostaglandins appear to be important determinants of peak flow. The effects of NO synthase inhibition during reactive hyperemia may also be potentiated by concurrent cyclooxygenase inhibition.
Development, control, and MRI-compatibility of the MR-SoftWrist (2015)

This paper presents the MR-SoftWrist: a parallel 3DOF MR-compatible wrist robot with compliant actuation. Through a design that aligns the wrist joint axes to the device DOFs and uses custom MR-compatible force-feedback actuation, the MR-SoftWrist can measure and support wrist movements during fMRI. The device has a circular workspace for wrist flexion/extension and radial/ulnar deviation with 18 deg radius, and is capable of generating 1.75 Nm joint torque. Control experiments validate the device's workspace, along with position and zero torque control capabilities. In zero torque mode the maximum force felt by the user is 0.15 Nm, less than 10% of the device's torque output. The device is shown to have no significant affect on imaging quality during fMRI.
Theory of magnetotransport in a composite medium with periodic microstructure for arbitrary magnetic fields (1994)

A method is described for calculating the magnetotransport properties of a two-component composite conducting medium which has a periodic microstructure. The method is based on a Fourier series expansion of the local electric potential. Because a large number of expansion coefficients needs to be used in order to get reliable results for the bulk effective behavior, a special approach is developed that does not require solving a large set of coupled linear algebraic equations for them. Results are presented for the magnetoresistance and Hall resistance as functions of the magnetic field in a number of models where periodic arrays of insulating inclusions of various shapes are embedded in a uniform host material. These samples include cases where the inclusions are well separated as well as cases where they touch and where they overlap.