gebhart/patrepeval huggingface dataset:
Stereospecific formation of enolates from reaction of unsymmetrical ketenes and organolithium reagents (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereospecific formation of enolates from reaction of unsymmetrical ketenes and organolithium reagentsLynn M. Baigrie, Hani R. Seiklay, and Thomas T. TidwellCite this: J. Am. Chem. Soc. 1985, 107, 19, 5391–5396Publication Date (Print):September 1, 1985Publication History Published online1 May 2002Published inissue 1 September 1985https://pubs.acs.org/doi/10.1021/ja00305a012https://doi.org/10.1021/ja00305a012research-articleACS PublicationsRequest reuse permissionsArticle Views2832Altmetric-Citations79LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Observation of Two-Dimensional Phases Associated with Defect States on the Surface of Ti<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">O</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (1976)

Surface electronic states associated with defects produced by Ar-ion bombardment of Ti${\mathrm{O}}_{2}$ crystals have been studied by ultraviolet-photoemission, electron-energy-loss, and Auger spectroscopy and low-energy-electron diffraction. Evidence is given for three distinct phases dependent upon the extrinsic surface-defect concentration. Phase I contains isolated surface states 0.7 eV below the conduction band, phase II is associated with the creation of ${\mathrm{Ti}}^{3+}$ pairs, and phase III consists of a surface layer of ordered ${\mathrm{Ti}}_{2}$${\mathrm{O}}_{3}$.
Activated Protein C Prevents Endotoxin-Induced Hypotension in Rats by Inhibiting Excessive Production of Nitric Oxide (2001)

These observations strongly suggest that APC inhibits iNOS induction by decreasing TNF-alpha production, leading to the prevention of ET-induced hypotension. Furthermore, such effects of APC were not dependent on its anticoagulant effects but rather on its serine protease activity.
A Survey Study of In-Situ Stereo and Multi-Channel Monitoring Conditions (2001)

The in-situ responses of a total of 372 loudspeakers in 164 professional monitoring rooms around the world have been measured after acoustical calibration. All measured rooms have been equipped with factory calibrated three way monitors and acoustically calibrated with standardized apparatus. The results provide a thorough understanding of typical monitoring conditions for stereo and multi-channel rooms, distribution in room parameters and quality of reproduced audio. Results are compared to current standards and recommendations.
Marked elevation of the chemokine CCL18/PARC in Gaucher disease: a novel surrogate marker for assessing therapeutic intervention (2003)

Gaucher disease is characterized by storage of glucosylceramide in lysosomes of tissue macrophages as the result of an autosomal recessively inherited deficiency in glucocerebrosidase. Progressive accumulation of these glycolipid-laden Gaucher cells causes a variety of debilitating symptoms. The disease can be effectively treated by costly intravenous infusions with recombinant glucocerebrosidase. Chitotriosidase is massively secreted by Gaucher cells and its plasma levels are used to monitor efficacy of enzyme therapy. Broad-scale application is hampered by the common genetic defect in this surrogate marker. We report that in plasma of symptomatic patients with Gaucher disease the chemokine CCL18 is on average 29-fold elevated, without overlap between patient and control values (median control plasma level is 33 ng/mL, range, 10-72 ng/mL; median Gaucher plasma level is 948 ng/mL, range, 237-2285 ng/mL). Plasma CCL18 concentrations decrease during therapy, comparably to chitotriosidase levels. Immunohistochemistry demonstrates that Gaucher cells are the prominent source of CCL18. Plasma CCL18 levels can serve as alternative surrogate marker for storage cells in patients with Gaucher disease and monitoring of plasma CCL18 levels proves to be useful in determination of therapeutic efficacy, especially in patients who are deficient in chitotriosidase activity. The potential physiologic consequences of chronically elevated CCL18 in patients with Gaucher disease are discussed.
A Generic Framework for Semantic Sports Video Analysis Using Dynamic Bayesian Networks (2005)

Automatic detection of semantic events in sport videos is a challenging task. In this paper, we propose a multimodal multilayer statistical inference framework for semantic sports video analysis using Dynamic Bayesian Networks (DBNs). Based on this framework, three instances including factorial hierarchical hidden Markov model (FHHMM), coupled hierarchical hidden Markov model (CHHMM), and product hierarchical hidden Markov model (PHHMM), are constructed and compared. Play-break detection in soccer videos is used as a testbed with hierarchical hidden Markov model (HHMM) as a baseline. Experimental results indicate the superior capability of the PHHMM, because it not only effectively models dynamic interactions between different modalities, but also sufficiently utilizes context constraints in multilayer structures.
Large area micropatterning of cells on polydimethylsiloxane surfaces (2014)

Using photolithography, it is possible to form patterns of high resolution stable at 37°C over 2 weeks, and microstructural complexity over large areas of a few cm(2). As a robust and scalable patterning method, this technique showing homogenous and stable cell adhesion and growth over macroscales can bring microfabrication a step closer to mass production for biomedical applications.
Conformation of Adsorbed Comb Copolymer Dispersants (2008)

Comb copolymers with an adsorbing backbone and nonadsorbing side chains can be very effective dispersants, particularly when a high ionic strength strongly penalizes electrostatic stabilization. For this reason, they have become essential components of concrete over the past decade. This article examines the steric hindrance characteristics of such polymers through the use of atomic force microscopy (AFM) on calcium silicate hydrate, the main hydration product of Portland cement. It is found that solution and surface properties (hydrodynamic radius, radius of gyration, surface coverage, steric layer thickness) and force-distance curves obtained during AFM measurements can be well described by a scaling approach derived in this paper. This represents the first real quantitative step in relating these properties directly to the molecular structure of such comb copolymer dispersants.
Ultrathin Antifouling Coatings with Stable Surface Zwitterionic Functionality by Initiated Chemical Vapor Deposition (iCVD) (2012)

Antifouling thin films of poly[N,N-dimethyl-N-methacryloxyethyl-N-(3-sulfopropyl)-co-2-(dimethylamino)ethyl methacrylate-co-ethylene glycol dimethacrylate] (PDDE) were synthesized via a substrate-independent and all-dry-initiated chemical vapor deposition (iCVD) technique followed by a diffusion-limited vapor-phase reaction with 1,3-propane sultone. Coated surfaces exhibited very low absorption of various foulants including bovine serum albumin (BSA), humic acid (HA), and sodium alginate (SA), as measured with the quartz crystal microbalance with dissipation monitoring (QCM-D). The fouling by humic acid was dependent on the presence of divalent cations such as Ca(2+). Both depth profiling and angle-resolved X-ray photoelectron spectroscopy (XPS) measurements indicated that the zwitterionic groups were highly concentrated in the top ~3 nm of the film. The contact angle measurements revealed a limited degree of surface chain reorganization upon contacting water. The dynamic contact angles remained unchanged after 100 days of storage in air, indicating the stability of the interface. The coating was substrate-independent, and the film was conformal on surface nanostructures including trenches, reverse osmosis membranes, and electrospun nanofiber mats.
Suppression of Overt Diabetes in NOD Mice by Anti-thymocyte Serum or Anti-Thy 1, 2 Antibody (1986)

Effects of anti-thymocyte serum (ATS) and anti-Thy 1, 2 monoclonal antibody on the spontaneously occurring diabetes in NOD mice were examined. Spontaneous diabetes in female mice was markedly suppressed by intravenous injection of rabbit anti-mouse thymocyte serum diluted to 1:4 on three consecutive days during the time period from 70 to 100 days after birth; the cumulative incidence of overt diabetes upto 195 days of age was greatly reduced and the onset of diabetes was delayed. Similar effect was observed with anti-Thy 1, 2 antibody treatment. These findings suggest that T lymphocytes play a role in the production of spontaneous diabetes in this mouse strain.
[The results of medicolegal proceedings involving dental care services]. (2012)

The paper deals with the results of medicolegal proceedings involving inappropriate dental care service in both criminal and civil cases. The authors also propose measures for prevention of pitfalls described in the study.
Efficient Error Control for Wireless Video Multicast (2006)

In this paper we develop joint source rate selection, power management, and error control schemes for wireless multicast of SNR scalable video. In particular, two error control schemes are analyzed and compared-type 2 hybrid ARQ/FEC (T2HA/F) and non-causal error control (NCEC). T2HA/F is based on incremental redundancy chosen to recover losses and provide the required level of video quality for all users. On the other hand, NCEC relies on error concealment from future video data whose quality is adaptively adjusted to bring the video quality up to the desired level for all users. Experimental results indicate that NCEC can be significantly more efficient than T2HA/F
Adrenergic Hyperactivity and Metanephrine Excess in the Nucleus Accumbens After Prefrontocortical Dopamine Depletion (2001)

Selective dopamine depletion within the medial prefrontal cortex in rats is known to enhance dopamine and norepinephrine levels in the nucleus accumbens and to induce characteristic behavioral disturbances. The present study was designed to determine levels of adrenaline, apart from dopamine and norepinephrine, and metabolites in the nucleus accumbens after prefrontocortical dopamine depletion. Prefrontocortical dopamine depletion was carried out by injecting 6-hydroxydopamine, and it was validated through: the emergence of behavioral disturbances such as amphetamine-induced stereotypies, spontaneous motor hyperactivity, and enhanced "anxiety-like" responses and through postmortem quantification of catecholamine levels by using high-performance liquid chromatography. The findings indicated that lesioned rats exhibited more oral stereotypies after amphetamine, were hyperlocomotive, and showed more pronounced anxiety-like behaviors than controls. Following prefrontocortical dopamine depletion, postmortem concentrations of dopamine and norepinephrine, along with the metabolites 3,4-dihydroxyphenylacetic acid and vanillylmandelic acid, were reliably enhanced in the nucleus accumbens as expected, and dopamine turnover was decreased. Furthermore the nucleus accumbens contained higher levels of adrenaline and its transmethylated metabolite metanephrine. To sum up, prefrontocortical dopamine depletion induces motor and emotional disturbances in rats and alters the neurochemical profile of the nucleus accumbens, not only inducing dopaminergic and noradrenergic hyperactivity but also leading to adrenaline and metanephrine excess.
Anaemia and related nutrient deficiencies after Roux-en-Y gastric bypass surgery: a systematic review and meta-analysis (2015)

RYGB surgery is associated with an increased risk of anaemia and deficiencies of iron and vitamin B12, but not folate. Ferritin is more sensitive when serum iron level is within normal range.
Decentralized Applications: The Blockchain-Empowered Software System (2018)

Blockchain technology has attracted tremendous attention in both academia and capital market. However, overwhelming speculations on thousands of available cryptocurrencies and numerous initial coin offering scams have also brought notorious debates on this emerging technology. This paper traces the development of blockchain systems to reveal the importance of decentralized applications (dApps) and the future value of blockchain. We survey the state-of-the-art dApps and discuss the direction of blockchain development to fulfill the desirable characteristics of dApps. The readers will gain an overview of dApp research and get familiar with recent developments in the blockchain.
Hydrogen sulfide poisoning: an antidotal role for sodium nitrite? (1997)

In 2 separate incidents, 6 patients were poisoned with hydrogen sulfide (H2S) in sewer gas. In the first incident, mixing acid- and sodium hydroxide-based drain cleaners in a confined space resulted in 4 poisonings and 2 deaths. Three would-be rescuers were seriously poisoned and 1 died. Two survivors had neurological sequelae. Sodium nitrite appeared to have some clinical efficacy in 1 case. The second incident involved 2 patients working on a pump in a sewage pond. A patient lying on a raft close to the pond surface was seriously poisoned; sodium nitrite was clinically efficacious and this patient survived without developing neurological sequelae. Sodium nitrite deserves further clinical study as a potential H2S antidote.
The <i>porA</i> gene in serogroup A meningococci: evolutionary stability and mechanism of genetic variation (1994)

Summary Molecular analyses were applied to the genes encoding variants of the serosubtyping antigen, the class 1outer membrane protein (PorA), from 55 serogroup A Neisseria meningitidis strains. These genes were evolutionarily stable and exhibited a limited range of genetic variation, primarily generated by recombination. Translation of the gene sequences revealed a total of 19 distinct amino acid sequences in the variable regions of the protein, 6 of which were not recognized by currently available serosubtyping monoclonal antibodies. Knowledge of these aminoacid sequences permitted a rational re‐assignment of serosubtype names. Comparison of the complete genes with porA gene sequences from serogroup B and C meningococci showed that serogroup A possessed a limited number of the possible porA genes from a globally distributed gene pool. Each serogroup A subgroup was characterized by one of four porA gene types, probably acquired upon subgroup divergence, which was stable over periods of decades and during epidemiological spread. Comparison with other variable genes (pil and iga) indicated that the three alleles were independently assorted within the subgroup, suggesting that their gene types were older than the subgroups in which they occurred.
THE PREPARATION OF RADIOACTIVE VITAMIN B<sub>12</sub> BY DIRECT NEUTRON IRRADIATION<sup>1</sup> (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE PREPARATION OF RADIOACTIVE VITAMIN B12 BY DIRECT NEUTRON IRRADIATION1R. Christian Anderson and Yvette DelabarreCite this: J. Am. Chem. Soc. 1951, 73, 8, 4051–4052Publication Date (Print):August 1, 1951Publication History Published online1 May 2002Published inissue 1 August 1951https://pubs.acs.org/doi/10.1021/ja01152a543https://doi.org/10.1021/ja01152a543research-articleACS PublicationsRequest reuse permissionsArticle Views24Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Surface photovoltage analysis of phase transformation of copper in p-type silicon (2000)

Surface photovoltage minority carrier lifetime/diffusion length analysis of copper contaminated p-type silicon was performed. It was observed that an optical or low-temperature thermal activation procedure on Cu-doped silicon significantly degrades the diffusion length. Unlike iron doped p-type silicon no recovery of diffusion length was observed following such an activation procedure. It is proposed that the activation procedure dissociates interstitial copper agglomerations and forms extended substitutional defects in silicon, which have much greater recombination efficiency. The change in phase of copper and the formation of associated defects is a function of activation light intensity, annealing time, and temperature. An activation energy of 0.419 eV is obtained for the process, which is in good agreement with copper diffusivity value in silicon. It is thus concluded that the change in phase of copper and the formation of extended defects with activation is a diffusion limited process.
The Magnus expansion for classical Hamiltonian systems (1991)

Lie operator techniques and the Magnus expansion are developed in the framework of classical mechanics. This leads to an exponential perturbation theory that preserves the canonical character at each order of approximation. The treatment is kept as close as possible to the quantum mechanical case in order take full advantage of the properties of the expansion. The explicit relationship with secular perturbation theory is established and a recursive procedure for obtaining higher-order approximants is provided. Finally, the formalism is applied to two problems of physical interest.
DMD‐specific FISH probes are diagnostically useful in the detection of female carriers of DMD gene deletions (1997)

The challenge of Duchenne muscular dystrophy (DMD) carrier identification resides in the ability to identify the presence of a mutant gene over the background contributed by the normal allele. Current diagnosis of carrier status when a deletion has been identified in a proband is based on an analysis of a gene dosage. We present a diagnostic strategy that uses fluorescence in situ hybridization (FISH) to detect female carriers with major deletions in the dystrophin gene. We screened a human X-chromosome-derived genomic library with a full-length dystrophin cDNA and isolated 15 dystrophin-specific cosmids that contain DMD gene exons. Six cosmids were further tested as FISH probes in control individuals and subsequently applied on chromosomes from eight males with DMD and known deletions and on samples from three female carriers. As expected, X chromosomes in normal females displayed four signals, two for the DMD-specific probe and two for the X-chromosome centromeric probe. Hybridization on chromosomal spreads from carriers of deletions revealed only one signal from the DMD-specific probe and two from the control centromeric probe. Males carrying deletions showed no DMD-specific signal for the deleted exons tested. Our data indicate that FISH could represent an alternative method for the detection of female carriers with DMD gene deletions.
Vibrissa dermal papilla cell aggregative behaviour <i>in vivo</i> and <i>in vitro</i> (1984)

Parallel cultures of adult rat vibrissa dermal papilla cells and skin fibroblasts revealed differences between the two cell types with respect to a number of criteria. In particular the dermal papilla cells demonstrated a distinctive single cell morphology, and at confluence formed cell aggregates radically different from regular fibroblast multilayering and patterning. This finding confirmed repeated observations of papilla cell clumping in short-term culture. The dermal papilla cells which are mitotically quiescent in situ were also shown to have a lower proliferative capacity than the skin fibroblasts. The affinity shown by papilla cells towards each other in culture reflected the behaviour demonstrated by isolated dermal papillae transplanted into ear dermis and into the collagenous capsule of the vibrissa follicle. In the absence of epidermal contact the papilla cells remained as recognizable rounded aggregates for the experimental period of up to nine months. Synthesis of extracellular material typical of that seen in situ was observed, particularly during the first weeks following transplantation. The collective behaviour of the dermal papilla cells revealed in this study may be significant for the morphogenetic activity of the papilla, and for papilla size during the hair cycle. It may also reflect the retention of embryonic-like properties by the dermal component of adult hair follicles.
Flexible all solid state supercapacitor with high energy density employing black titania nanoparticles as a conductive agent (2016)

Increasing the electrical conductivity of pseudocapacitive materials without changing their morphology is an ideal structural solution to realize both high electrochemical performance and superior flexibility for an all solid state supercapacitor (ASSSC). Herein, we fabricate a flexible ASSSC device employing black titania (TiO2-x:N) decorated two-dimensional (2D) NiO nanosheets as the positive electrode and mesoporous graphene as the negative electrode. In this unique design, NiO nanosheets are used as pseudocapacitive materials and TiO2-x:N nanoparticles serve as the conductive agent. Owing to the excellent electrical conductivity of TiO2-x:N and well defined "particle on sheet" planar structure of NiO/TiO2-x:N composites, the 2D morphology of the decorated NiO nanosheets is completely retained, which efficiently reinforces the pseudocapacitive activity and flexibility of the whole all solid state device. The maximum specific capacitance of fabricated the NiO/TiO2-x:N//mesoporous graphene supercapacitor can reach 133 F g(-1), which is 2 and 4 times larger than the values of the NiO based ASSSC employing graphene and carbon black as the conductive agent, respectively. In addition, the optimized ASSSC displays intriguing performances with an energy density of 47 W h kg(-1) in a voltage region of 0-1.6 V, which is, to the best of our knowledge, the highest value for flexible ASSSC devices. The impressive results presented here may pave the way for promising applications of black titania in high energy density flexible storage systems.