gebhart/patrepeval huggingface dataset:
The stress-induced escape of migrating aluminium from silicide interconnects (2001)

Electromigration of foreign aluminium atoms, arising from contact pads, along polycrystalline molybdenum silicide (MoSi2) metallic interconnect lines has been studied. The MoSi2-lines with aluminium contact pads on both ends were exposed to electric direct current with densities of between 106 and 107 A cm-2 over 2000 h. While mass transport of constituent atoms of the line material was not observed, the atomic migration of aluminium is clearly directed from the cathode side toward the anode. Characteristic hillocking along the interconnect line is observed. This result is in accord with the action of a partially grain-blocked polycrystalline via due to clusters, which are present along the line. Compressive stress in front of blocking silicide grains is found to induce a positive mass flux through the line surface. Scanning electron microscopy micrographs, and energy-dispersive x-ray analyses are applied to identify the chemical nature of the degradation sites. It is found that aluminium from the cathode pad incorporates into the interconnect and migrates under the action of the electron wind.
Immobilization of Gold Nanoparticles onto Silicon Surfaces by Si−C Covalent Bonds (2004)

A series of ω-alkene-1-thiol-stabilized gold nanoparticles were prepared by a wet process and then covalently linked to a hydrogen-terminated silicon(111) surface with Si−C bonds via a thermal hydrosilylation reaction. The modified silicon surfaces were observed mainly by high-resolution scanning electron microscopy (HR-SEM). The HR-SEM images revealed that the gold nanoparticles protected with 2-propene-1-thiol (C3) were covalently bound to the hydrogen-terminated silicon surface, after which the nanoparticles self-fused; on the other hand, gold nanoparticles protected with 5-hexene-1-thiol (C6) or 10-undecene-1-thiol (C11) were linked to the hydrogen-terminated silicon surface independently. These surfaces were stable in air and can be stored for several months without detectable decomposition.
Epileptogenicity Correlated with Increased <i>N</i>‐Methyl‐<scp>d</scp>‐Aspartate Receptor Subunit NR2A/B in Human Focal Cortical Dysplasia (2000)

These studies provide direct evidence for a major contribution of the NR2A/B subunit in CD-induced epileptogenicity.
A Threat to Mobile Cyber-Physical Systems: Sensor-Based Privacy Theft Attacks on Android Smartphones (2013)

The powerful processors and variety of sensors on nowaday smartphones make them being ideal mobile cyberphysical systems. However, these advantages can also be used to launch serious sensor-based privacy theft attacks through sensors abusing. In this paper, a sensor-based voice privacy theft attack named CPVT is presented. The attack will be detected easily if not processed appropriately, since voice data usually has high data rate and special permissions are needed for voice recording and data sending. We introduce two measures in CPVT to resolve the problems, with which CPVT can be disguised as a normal Android APP and the attack process can be fully controlled by the attacker without the knowledge of the victim. Experiments are taken out to verify the effectiveness and efficiency of CPVT, and the results demonstrate that the cyber-physical privacy theft attacks can be realized effectively on mobile terminals with good concealment and low overhead. This may be a very severe threat to mobile cyber-physical systems.
The Study of a Handheld Digital Microscope for Biomedical Applications (2008)

In recent years, biotechnology is a highly developed and popular research topic. Microorganism behavior measurement is an important method for biotechnology experiment. Microscope is often used to measure microorganism behavior. The disadvantages of using the tradition microscope are expensive, heavy when the magnification is too large it's not easy to tracking microorganism. In this research, we focus on the development of a low-cost and convenient hand-held digital microscope platform. Based on digital microscope technology, we can observe and record any tiny object's behavior and movement, like Paramecium behavior etc. The platform is not only low-cost, easy to operation, but it can also connect to a computer for further data processing and analysis it let the digital microscope can be used in many applications.
Learning to remove Internet advertisements (1999)

ADEATER is a fully implemented browsing assistant that automatically removes advertisement images from Internet pages. Unlike related systems that rely on hand-crafted rules, ADEATER takes an inductive learning approach, automatically generating rules from training examples. Our experiments demonstrate that our approach is practical: the off-line training phase takes less than six minutes; on-line classification takes about 70 msec; and classification accuracy exceeds 97% given a modest set of training data.
Isolation and identification of a novel human parechovirus (2004)

A cytopathic agent (A308/99) was isolated using Vero cells from a stool specimen of a 1-year-old patient with transient paralysis. The agent was approximately 28 nm in diameter with a distinct ultrastructure resembling the virus particle of an enterovirus. It could not be neutralized by antisera against human picornaviruses such as human enterovirus, Aichi virus or human parechovirus. The virion contained three capsid proteins with molecular masses of 38, 30.3 and 30 kDa. Determination of the complete nucleotide sequence of A308/99 revealed that the nucleotide and deduced amino acid sequences were closely related to those of human parechoviruses. When 11 regions encoding the structural and non-structural proteins were compared, A308/99 had between 75 and 97 % and 73 and 97 % nucleotide identity with human parechovirus type 1 (HPeV-1) and type 2 (HPeV-2), respectively. The most distinctive divergence was seen in VP1, which had 74.5 % and 73.1 % nucleotide identity with HPeV-1 and HPeV-2, respectively. Viruses related to A308/99 were also isolated from three patients with gastroenteritis, exanthema or respiratory illnesses. A308/99 and these other three isolates had no arginine-glycine-aspartic acid (RGD) motif, which is located near the C terminus of VP1 in HPeV-1 and HPeV-2. A seroepidemiological study revealed that the prevalence of A308/99 antibodies was low (15 %) among infants but became higher with age, reaching more than 80 % by 30 years of age. These observations indicate that A308/99 is genetically close to, but serologically and genetically distinct from, HPeV-1 and HPeV-2 and accordingly can be classified as third serotype of human parechovirus.
CD34+/CD105+ cells are enriched in primitive circulating progenitors residing in the G0 phase of the cell cycle and contain all bone marrow and cord blood CD34+/CD38<sup>low/−</sup> precursors (2000)

A subset of circulating CD34+ cells was found to express CD105 antigen. Sorting experiments showed that most granulocyte-macrophage colony-forming units (GM-CFU) and burst-forming units - erythroid (BFU-E) were retained in the CD34+/CD105- fraction, whereas rare GM-CFU/BFU-E were generated from CD34+/CD105+ cells. Megakaryocytic aggregates were entirely retained in the CD34+/CD105+ fraction. Neutralizing doses of an anti-TGF-beta1 antibody demonstrated CD34+/CD105+ cells capable of colony-forming activity without any significant effect on CD34+/CD105- cells. Cloning of secondary colonies revealed that CD34+/CD105+ cells had a significantly higher secondary cloning efficiency than CD34+/CD105- cells. CD34+/CD105+ cells had a significantly higher long-term culture-initiating cell (LTC-IC) frequency than CD34+/CD105- cells. Kinetic analysis showed that 75% of CD34+/CD105+ cells consisted of DNA 2n G0Ki-67- cells whereas 82% of CD34+/CD105- were DNA 2n G1Ki-67+ cells, and this latter subset showed a RNA content consistently higher than CD34+/CD105+ cells. CD34+/CD105+ progenitors were CD25+, whereas CD34+/CD105- contained a small CD25+ subset. Three-colour analysis of bone marrow and cord blood CD34+ cells demonstrated that all the CD34+/CD38low/- primitive precursors were contained in CD34+/CD105+ cells. Extensive characterization of these CD105+ precursors indicated that they have biological properties associated with primitive haematopoietic precursors.
Biotechnology, Invertebrate Pathology, and Cell Culture (1986)

It has become apparent from publications, meetings, and discussions that there is an increasing interest in biotechnological advances and applications to insect pathology, particularly in the United States and Japan. To provide direct exchange of information among the diverse areas of gene manipulation and biotechnology as related to invertebrate pathology, the National Science Foundation and the Japan Society for Promotion of Science were appraoched to sponsor a U.S.–Japan seminar on this subject. Both organizations jointly agreed to sponsor the seminar by supporting the travel and living expenses of eight United States and eight Japanese participants. Following the grant approval, the number of participants was enlarged to include additional university and industry experts from the United States, Canada, Germany, India, Israel, Kenya, and Switzerland. This brought the total number of participants to 36 and gave the meeting an international, rather than binational character. Consequently, the seminar provided a unique international opportunity for direct contacts and direct exchange of information among the diverse areas of gene manipulation and biotechnology applications to invertebrate pathology.
Slow-binding inhibition of sialidase from influenza virus. (1994)

Sialidase from influenza virus A (Tokyo/3/67, N2) is inhibited in slow-binding fashion by 2,3-didehydro-2,4-dideoxy-4-guanidino-N-acetyl-D-neuraminic acid. The Ki observed for the tightly-bound form at steady-state is 3 x 10(-11) M. Slow-binding, which is a consequence of the guanidinyl moiety of the inhibitor, is observed only for influenza virus A sialidase and not for influenza virus B or any other viral, bacterial, or mammalian sialidase investigated. The different results obtained for sialidases from influenza virus A and B, whose active sites are conserved, point to the involvement of the expulsion of a structural water molecule in the slow-binding mechanism.
A Designed System for Assessing How Sequence Affects α to β Conformational Transitions in Proteins (2002)

The role of amino acid sequence in conformational switching observed in prions and proteins associated with amyloid diseases is not well understood. To study α to β conformational transitions, we designed a series of peptides with <i>structural duality</i>; namely, peptides with sequence features of both an α−helical leucine zipper and a β−hairpin. The parent peptide, Template−α, was designed to be a canonical leucine-zipper motif and was confirmed as such using circular dichroism spectroscopy and analytical ultracentrifugation. To introduce β−structure character into the peptide, glutamine residues at sites away from the leucine-zipper dimer interface were replaced by threonine to give Template−αT. Unlike the parent peptide, Template−αT underwent a heat-inducible switch to β−structure, which reversibly formed gels containing amyloid-like fibrils. In contrast to certain other natural proteins where destabilization of the native states facilitate transitions to amyloid, destabilization of the leucine-zipper form of Template−αT did not promote a transformation. Cross-linking the termini of the peptides compatible with the alternative β−hairpin design, however, did promote the change. Furthermore, despite screening various conditions, only the internally cross-linked form of the parent, Template−α, peptide formed amyloid-like fibrils. These findings demonstrate that, in addition to general properties of the polypeptide backbone, specific residue placements that favor β−structure promote amyloid formation.
Did you ever have to make up your mind? What Notes users do when faced with a security decision (2003)

Designers are often faced with difficult tradeoffs between easing the user's burden by making security decisions for them and offering features that ensure that users can make the security decisions that are right for them and their environment. Users often do not understand enough about the impact of a security decision to make an informed choice. We report on the experience in a 500-person organization on the security of each user's Lotus Notes client against unsigned active content. We found that the default configuration of the majority of users did not allow unsigned active content to run. However, we found that when presented with a choice during their workflow, many of those otherwise secured users would allow unsigned active content to run. We discuss the features that are in Lotus Notes that provide security for active content and that respond to the usability issues from this study.
Ultrastable PbSe Nanocrystal Quantum Dots via <i>in Situ</i> Formation of Atomically Thin Halide Adlayers on PbSe(100) (2014)

The fast degradation of lead selenide (PbSe) nanocrystal quantum dots (NQDs) in ambient conditions impedes widespread deployment of the highly excitonic, thus versatile, colloidal NQDs. Here we report a simple in situ post-synthetic halide salt treatment that results in size-independent air stability of PbSe NQDs without significantly altering their optoelectronic characteristics. From TEM, NMR, and XPS results and DFT calculations, we propose that the unprecedented size-independent air stability of the PbSe NQDs can be attributed to the successful passivation of under-coordinated PbSe(100) facets with atomically thin PbX2 (X = Cl, Br, I) adlayers. Conductive films made of halide-treated ultrastable PbSe NQDs exhibit markedly improved air stability and behave as an n-type channel in a field-effect transistor. Our simple in situ wet-chemical passivation scheme will enable broader utilization of PbSe NQDs in ambient conditions in many optoelectronic applications.
Three novel germline mutations in exons 8 and 18 of the retinoblastoma gene (1994)

Journal Article Three novel germline mutations in exons 8 and 18 of the retinoblastoma gene Get access Véronique Blanquet, Véronique Blanquet * *To whom correspondence should be addressed Search for other works by this author on: Oxford Academic PubMed Google Scholar Marie Sylvie Gross, Marie Sylvie Gross Search for other works by this author on: Oxford Academic PubMed Google Scholar Catherine Turieau, Catherine Turieau Search for other works by this author on: Oxford Academic PubMed Google Scholar Catherine Sénamaud-Beaufort, Catherine Sénamaud-Beaufort Search for other works by this author on: Oxford Academic PubMed Google Scholar Francols Doz, Francols Doz 1Institut Curie26 rue d'Ulm, 75231 Paris 05, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Claude Besmond Claude Besmond 2INSERM U91, Hopital Henri Mondor51 avenue de Tassigny, Créteil, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Human Molecular Genetics, Volume 3, Issue 7, July 1994, Pages 1185–1186, https://doi.org/10.1093/hmg/3.7.1185 Published: 01 July 1994 Article history Received: 14 March 1994 Revision received: 04 May 1994 Accepted: 04 May 1994 Published: 01 July 1994
Hierarchical Self-Assembly of Gold Nanoparticles into Patterned Plasmonic Nanostructures (2014)

The integration of nanoparticle superstructures into daily life applications faces major challenges including the simplification of the self-assembly process, reduced cost, and scalability. It is, however, often difficult to improve on one aspect without losing on another. We present in this paper a benchtop method that allows patterning a macroscopic substrate with gold nanoparticle supercrystals in a one-step process. The method allows parallelization, and patterned substrates can be made with high-throughput. The self-assembly of a variety of building blocks into crystalline superstructures takes place upon solvent evaporation, and their precise placement over millimeter scale areas is induced by confinement of the colloidal suspension in micron-sized cavities. We mainly focus on gold nanorods and demonstrate their hierarchical organization up to the device scale. The height of the formed nanorod supercrystals can be tuned by simply varying nanorod concentration, so that the topography of the substrate and the resulting optical properties can be readily modulated. The crystalline order of the nanorods results in homogeneous and high electric field enhancements over the assemblies, which is demonstrated by surface-enhanced Raman scattering spectroscopy.
Efficient Similarity Search by Summarization in Large Video Database (2007)

With the explosion of video data, video processing technologies have advanced quickly and been applied into many fields, such as advertisements, medical etc. To fast search these video data, an important issue is to effectively organize videos by data compacting and indexing. However, practically, many useful distances for video comparison are suitable to human perception, but non-metric. Therefore, traditional high dimensional data structures can not be utilized to index videos directly when non-metric measures are applied. In this paper, we propose a compact video representation based on global summarization, by which each video in database is mapped into a digital string(a series of cluster id). Consequently, the inter-frame similarity measure is transformed into inter-cluster comparison. Then, we propose an efficient index strategy based on sequence decomposition and reconstruction, by which the spatial index methods can be utilized with non-metric measures for video similarity search. We employ an optimal B+-tree with an inverted list attached, for quickly identifying similar clusters and locating potentially similar videos respectively. Finally, a clustering based query summarization technique is proposed, which can greatly reduce the IO and CPU cost in the query processing by batch mapping.
Abolition of Cyclin-Dependent Kinase Inhibitor p16 <sup> <i>Ink4a</i> </sup> and p21 <sup> <i>Cip1/Waf1</i> </sup> Functions Permits Ras-Induced Anchorage-Independent Growth in Telomerase-Immortalized Human Fibroblasts (2003)

Human cells are more resistant to both immortalization and malignant transformation than rodent cells. Recent studies have established the basic genetic requirements for the transformation of human cells, but much of this work relied on the expression of transforming proteins derived from DNA tumor viruses. We constructed an isogenic panel of human fibroblast cell lines using a combination of gene targeting and ectopic expression of dominantly acting mutants of cellular genes. Abolition of p21(Cip1/Waf1) and p16(Ink4a) functions prevented oncogenically activated Ras from inducing growth arrest and was sufficient for limited anchorage-independent growth but not tumorigenesis. Deletion of the tumor suppressor p53 combined with abolition of p16(Ink4a) function failed to mimic the introduction of simian virus 40 large T antigen, indicating that large T antigen may target additional cellular functions. Ha-Ras and Myc cooperated only to a limited extent, but in the absence of Ras, Myc cooperated strongly with the simian virus 40 small t antigen to elicit aggressive anchorage-independent growth. The experiments reported here further define specific components of human transformation pathways.
Study and Application of Novel Optical Fiber Probes (2002)

The novel optical fiber probes,which can be used in near-field detection,are fabricated by means of combination of melting-pulling and fretting.This method has merits of cheaper fee and reproducible,and without fine and complicated equipment.The straight tapered probes covered with Au membrane are first used in the scanning tunnel microscopy (STM).Because the curvature of the optical fiber probes is smaller than the probe made of Pt-Ir,the information and images obtained are finer and subtler.The bent fiber probes fixed in a special mount can be as a sort of cantilever probe used in the force microscope (AFM) and scanning near-field optical microscope (SNOM).We finally discussed the influence of the different shapes of the tips and the different metallic material membranes on the experimental results.
NOMINATA DE AVALIADORES 2017 (2017)

O Comitê Editorial da REUNIR: Revista de Administração, Ciências Contábeis e Sustentabilidade da Universidade Federal de Campina Grande, agradece aos professores e pesquisadores que vêm colaborando para o aprimoramento da qualidade do conteúdo dos trabalhos divulgados pela revista no ano de 2017.A REUNIR deve, em grande parte seu crescimento e evolução da sua posição no Qualis CAPES (Área de Administração Pública e de Empresas, Ciências Contábeis e Turismo e demais áreas) ao trabalho voluntário, prestativo e de qualidade desses avaliadores e de toda a equipe que faz parte do periódico. Esperamos contar com essa parceria em anos posteriores. Na oportunidade, externamos nossos sinceros votos de Feliz Natal e Próspero Ano Novo. Sousa, PB, 22 de Dezembro de 2017. Dr. José Ribamar Marques de CarvalhoEditor-Chefe Responsável DOI: 10.18696SPELL: http://www.spell.org.br/periodicos/ver/138/reunir--revista-de-administracao--contabilidade-e-sustentabilidadeQualis CAPES:B2 – Área de Administração Pública e de Empresas, Ciências Contábeis e TurismoB2 – Planejamento Urbano e Regional / DemografiaB2 – InterdisciplinarB5 – Ciências Agrárias IB4 – Ciências AmbientaisB4 – EconomiaB4 – Engenharias IB5 – Engenharias III Fonte: Plataforma Sucupira, Disponível em: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/veiculoPublicacaoQualis/listaConsultaGeralPeriodicos.jsf. Acesso em: 22 dez. 2017
TOWARDS A DECISION SUPPORT SYSTEM FOR ENGINEERING CHANGE MANAGEMENT (2014)

With the growing complexity in product development processes, the rapid market alterations and the raising criticality of leadtime, the Engineering Change Management (ECM) is becoming important to all organizations. One of the primary challenges in this area is the management of all information associated with the change and taking a wise decision respectively. As the human brain, could only consider limited amount of variables at a time, this paper conceptualizes the development of a Decision Support System for ECM to utilize the past information for current decision making processes.
Cell-Permeable and Biocompatible Polymeric Nanoparticles for Apoptosis Imaging (2006)

Here, we report for the first time cell-permeable and biocompatible polymeric nanoparticles consisting of a polymer conjugated to a near-infrared (NIR) fluorescence (Cy5.5)-linked effector caspase-specific peptide. The close spatial proximity of the NIR fluorochromes in polymeric nanoparticles results in an autoquenched state, but polymer nanoparticles give rise to strong NIR fluorescence signal under apoptotic cells. Thus, the smart polymeric nanoparticle developed here is an attractive probe for real-time imaging of apoptosis in single cells.
A TEMPLATE-BASED FLOOR SHAPE RECOGNITION APPLIED TO 3D BUILDING SHAPES OF GIS DATA (2014)

統合地震シミュレーションでは，都市の建物一棟一棟のモデル構築に市販のGISデータを利用する．このデータは本来図示を目的とし，独立した多角形の集合として記述されているため，有限要素法のモデルに代表される節点と要素からなる解析モデルの自動構築には困難を伴う．本論文は，モデル形状の構築をテンプレートフィッティングという床形状判読で行う新しい方法論を提案する．テンプレートフィッティングは，多様な床形状に対応してあらかじめ多数準備されたテンプレートから，判読対象に最も形状が近いテンプレートを選択する．テンプレートに，柱・壁の配置等の内部構造を前もって仮定し付加すれば，建物各階の平面形状を反映したモデルが堅牢に自動構築でき，その結果として建物モデル全体の堅牢な自動構築が可能である．
Immunoaffinity Purifications of Aminopeptidase P from Guinea Pig Lungs, Kidney and Serum (1994)

Previously, aminopeptidase P (AmP) has been purified from mammalian tissues by highly laborious multistep chromatography procedures. To simplify purifications, we raised a monoclonal antibody to guinea pig serum AmP and used the antibody to prepare an immunoaffinity matrix. The immunoaffinity matrix was used to obtain highly purified forms of AmP from guinea pig lungs, kidney and serum. The antibody is reactive with rat and human forms of AmP and may simplify procedures needed for their purifications.