gebhart/patrepeval huggingface dataset:
Video frames interpolation using adaptive warping (2010)

In this dissertation, a strategy for high fidelity scaling of video frames to higher resolutions is introduced. The method employed is a combination of block matching-based motion estimation and optical-based motion estimation, which builds on the Control Grid Interpolation (CGI) methods. Low resolution images are interpolated and used to obtain motion vectors that are then used to warp high definition reference frames. Because motion estimation is an ill-posed problem, robustness is critical in the motion search procedure. To improve the robustness of the derived motion fields, a bidirectional motion estimation method is proposed. A hierarchical motion structure is used to solve the ambiguity in the framework. Improving the spatial quality of video coded at low bit rates is a problem of general interest. Toward this end, a combined forward-backward warping method is proposed to improve the resolution of video encoded with H.264/AVC. The scheme attempts to capture long-term spatial detail by warping high resolution reference frames in accordance with displacement vectors derived from decoded low resolution frames. At low bit rates, the proposed method can achieve better PSNRs and better subjective quality than conventional H.264/AVC for sequences with low to moderate motion. The third application considered in this dissertation is video frame rate up-conversion. A new inter-frame motion compensated interpolation method is proposed that employs motion vector correction based on residual energy. Experimental results show that it can improve the visual quality of the interpolated frames where competing methods fail.
Effects of lipoxin A<sub>4</sub> on chemotaxis and degranulation of human eosinophils stimulated by platelet‐activating factor and <i>N</i>‐formyl‐L‐methionyl‐L‐leucyl‐L‐phenylalanine (1994)

Lipoxins are trihydroxytetraene metabolites derived through a double lipoxygenation of arachidonic acid. Lipoxin A4 (LXA4) was prepared by total chemical synthesis, and its capacity to modulate eosinophil migration has been evaluated. LXA4 is a weak and partial chemotactic agent; at 10(-6) M, it achieved about 20% of the response of 10(-6) M platelet-activating factor (PAF). Preincubation of eosinophils with increasing doses of LXA4 (10(-10)-10(-5) M) resulted in a concentration-dependent inhibition of cell migration induced by 10(-6) M formyl-methionyl-leucyl-phenylalanine (FMLP) and 10(-6) M PAF. The concentration of LXA4 which produced 50% inhibition (IC50) of eosinophil migration was approximately 10(-6) M. LXA4 (10(-10)-10(-6) M) did not elicit ECP release or modulate ECP release induced by 10(-6) M FMLP. LXA4 may have antiallergic properties in preventing eosinophilic migration.
Matrix Metalloproteinase Inhibition Facilitates Cell Death in Intracerebral Hemorrhage in Mouse (2007)

Intracerebral hemorrhage (ICH) initiates an inflammatory response with secondary growth of hemorrhage and cell death. Matrix metalloproteinase (MMP) gelatinolytic activity is increased in ICH, and synthetic inhibitors to MMPs reduce edema and hemorrhage size. Recently, we found that tissue inhibitor of metalloproteinase-3 (TIMP-3) is elevated after ischemia and colocalizes with TUNEL (terminal deoxynucleotidyl transferase-mediated 2'-deoxyuridine 5'-triphosphate-biotin nick end-labeled)-labeled cells. Tissue inhibitor of metalloproteinase-3 promotes neuronal apoptosis in vitro by blocking the shedding of the tumor necrosis factor (TNF) superfamily of death receptors/ligands by stromelysin-1 (MMP-3). However, the effect of TIMP-3 and synthetic MMP inhibitors on cell death in ICH is unclear. Therefore, we used the collagenase-induced intracerebral hemorrhage (CIH) model in Timp-3 knockout and C57Bl/6 wild-type mice to study MMP expression, hemorrhage volume, and cell death. Real-time PCR showed an increase in Mmp-3 mRNA in CIH, but similar Mmp-2 and -9 mRNA expression levels in CIH and saline-injected mice. Protein levels of pro and cleaved MMP-3 were increased in CIH, and zymographic gelatinolytic activity of MMP-9 was elevated after CIH at 72 h, suggesting an exogenous source. Apoptosis was shown by increased caspase-3 levels at 2 and 72 h, and active caspase-8 by 2 and 24 h. The Timp-3 null mouse and wild types had similar hemorrhage sizes and TUNEL-labeled cells. Unexpectedly, the broad-spectrum MMP inhibitor BB-94 increased hemorrhage size and TUNEL-labeled cells. Our results fail to implicate TIMP-3 in apoptosis in CIH, but show that BB-94 increased apoptosis in CIH, possibly by blocking shedding of TNF death receptors and/or their ligands.
Performance Evaluation of TCP-Based Traffic over Direct Communications in LTE-Advanced (2016)

Direct (or device-to-device, D2D) communications are being investigated in the framework of LTE- Advanced. They allow one-to-one communications between two endpoints, under the control of the eNodeB, which allocates resources for the d2d flow, but does not act as a relay for its traffic. The direct link can also be used for file transfer or proximity-based browsing, i.e. applications running on TCP. In this paper, we evaluate the performance of TCP-based traffic transported through the direct link, in several scenarios. We show and explain non-intuitive results, which arise from the interplay of TCP and LTE-A protocol mechanisms, and compare the existing TCP versions in a dynamic environment, where mode switches between the direct and the infrastructure link may induce periodic losses.
Design of finite impulse response transmitter and receiver filters for data communication system (1996)

Abstract Finite impulse response (FIR) transmitter and receiver filters for data transmission require both frequency domain and time domain approximation simultaneously. Previously, linear programming techniques have been used to design such filters; however, those techniques require many calculations and lengthy computation time. Proposed here is the design method of FIR transmitter and receiver filters for data transmission that uses the successive projections method. The design method of a matched filter pair is first described. It can have maximum signal‐to‐noise ratio (SNR) when Gaussian noise exists on the transmission line and where both the transmitter and receiver filters have the same amplitude response. Since the matched filter has double zeros in the stopband, it can also be used to derive the transfer function of a bandpass minimum phase filter. Then, the value of zero in the sampling interval is chosen such that total impulse response of the matched filter pair has zero intersymbol interference. A design method with constraint in time domain is thus described.
Fullerene-free polymer solar cells processed from non-halogenated solvents in air with PCE of 4.8% (2016)

Progress towards practical organic solar cells amenable to large scale production is reported. Fullerene-free organic solar cells with a PCE of ∼4.8% are achieved based upon an active layer composed of the standard donor polymer PTB7-Th and a highly soluble twisted PDI acceptor tPDI-Hex. All devices can be fabricated and tested in air with 'as-cast' active layers being processed from the greener solvents o-xylene (or trimethyl benzene) or the eco-friendly and bio-derived solvent 2Me-THF without loss in efficiency.
A Serologic Correlate of Protective Immunity Against Community-Onset Staphylococcus aureus Infection (2013)

Cutaneous S. aureus infection does not reliably provoke durable, protective immune responses. This study provides the first link between protection from disease recurrence and the humoral response to Hla, a virulence factor already implicated in disease pathogenesis. These observations can be utilized to refine ongoing vaccine and immunotherapy efforts and inform the design of clinical trials.
Correlation of optical coherence tomography and fundus fluorescein angiography following photodynamic therapy for choroidal neovascular membranes (2006)

The presence of subretinal fluid, intraretinal fluid in the form of gross cystoid macular oedema, or sponge-like retinal thickening, or a retinal thickness more than 350 mum correlates with leaks on FFA and so suggests the need for repeat PDT.
Creep Resistant Magnesium Alloys for Powertrain Applications (2003)

Abstract Creep resistant magnesium alloys are candidate materials for automotive powertrain applications. Since the 90's, a number of new creep‐resistant magnesium alloy systems have been investigated and developed. These are for the most part based on rare‐earth, alkaline earth, and silicon additions. This paper gives an overview of creep resistance in magnesium and a review of creep resistant magnesium alloys for power‐train applications.
Risk stratification and pathological mechanisms in preterm delivery (2001)

The delivery of infants before 37 weeks gestation is a leading cause of perinatal mortality and morbidity in the United States. Traditional methods of predicting women at risk relying on obstetric history or premonitory symptoms (detected clinically or by tocodynamometry) are neither sensitive nor specific. Recent approaches to predicting preterm delivery have included sonographic measurement of cervical length and various biochemical assays. Although more sensitive than traditional methods, none of these alone exhibits sufficient accuracy to warrant widespread use. We contend that the failure of current approaches to predicting preterm delivery reflects an inadequate understanding of the underlying pathogenesis. Clinical and experimental evidence support the concept that most cases of preterm delivery reflect four pathogenic processes, which share a common final biological pathway leading to uterine contractions and cervical changes with or without premature rupture of membranes. These pathogeneses are: (1) activation of the maternal or fetal hypothalamic-pituitary-adrenal axis; (2) decidual-chorioamniotic or systemic inflammation; (3) decidual haemorrhage (i.e. abruption); and (4) pathological distention of the uterus. Our research seeks to combine the most useful biophysical and biochemical markers of such processes with optimal clinical and epidemiological predictors into a composite, easily applied risk tool. This integrated approach has the potential to identify at-risk asymptomatic patients with high sensitivity, specificity, and positive and negative predictive values, and also to ascertain underlying pathogenic processes that can lead to targeted therapy. To accomplish these goals, we employ logistic regression and artificial neural network models to assess and apply the appropriate weight to markers associated with each of the above pathogenic pathways, in addition to markers of the final common pathway leading to fetal membrane rupture, cervical extracellular matrix degradation, and myometrial activation. By combining these markers, we expect ultimately to produce a predictive model that is more robust than any existing method, and that identifies the relative contribution of each pathogenic process. Further analysis of this model using a neural network will enable us to identify asymptomatic patients destined to deliver preterm with high sensitivity, specificity, positive and negative predictive values, and to assess the relative contribution of each of the four distinct pathogeneses to this preterm delivery risk.
Distribution of Intraocular Pressure (1997)

In the black participants, the IOP was higher than in the white participants. The IOP was also associated with age and cup-disc ratios. The results showed that open-angle glaucoma and a high IOP alone have a different distribution by sex; although open-angle glaucoma was more frequent in men, ocular hypertension was more frequent in women. These data have implications for the detection and causation of open-angle glaucoma in this high-risk population.
Analysis on the application of medium distribution voltage and voltage series (2010)

The Chinese power grids have formed relatively uniform voltage series,which have contributed greatly to the development of power grids as well as the economy and society.However,as the economy and power grids keep developing fast,there are spaces and necessities of further adjusting and simplifying voltage series.Therefore,the two grid companies in China conducted comprehensive research on voltage series optimization in the last two years.The development voltage classes and voltage series in China and foreign countries were introduced and analyzed,their evolution laws and trends were generalized,and more importantly,by analyzing typical cases,it summarizes the major modes of improving medium distribution voltage.It can serve as a reference to power grid companies conducting voltage series optimization.
Probing Potential-Tuned Resonant Tunneling through Redox Molecules with Scanning Tunneling Microscopy (1996)

We have studied electron transfer through redox molecules adsorbed on a conductive substrate with scanning tunneling microscopy (STM) in aqueous solution. By adjusting the substrate potential, the Fermi levels of the substrate and tip can be easily shifted relative to the energy levels of the molecules. Aligning the Fermi levels to an energy level, a nearly tenfold increase in the tunneling current that flows between the substrate and the STM tip via the molecules, due to resonant tunneling is observed. This experiment also shows that structurally similar molecules may be identified with STM based on their different redox properties.
A Semiautomatic Method for Interpreting Shearing Interferograms (1968)

We describe a system for testing mirrors and lenses which uses a lateral shearing interferometer and laser light source, and in which data are recorded and processed digitally to obtain a description of the test wavefront in terms of a polynomial function, from which the shape of the test mirror may be computed. Precision of the system is about 0.1lambda. It represents a step in the development of a completely automatic testing procedure.
Two COOH-Terminal Truncated Cytoplasmic Forms of Topoisomerase IIα in a VP-16-Selected Lung Cancer Cell Line Result from Partial Gene Deletion and Alternative Splicing (1997)

Topoisomerase II alpha is a nuclear enzyme involved in chromosome segregation and other essential cellular processes. It is also the target of several clinically important antineoplastic agents such as the epipodophyllotoxin, VP-16 (etoposide). We have previously described a VP-16-selected lung cancer cell line, H209/V6, that expresses reduced levels of two species of topoisomerase II alpha-related mRNAs and a catalytically active, predominantly cytoplasmic topoisomerase II alpha-related protein that is 10 kDa smaller than the wild-type protein [Mirski, S. E. L., et al. (1993) Cancer Res. 53, 4866-4873; Feldhoff, P. W. et al. (1994) Cancer Res. 54, 756-762]. The smaller H209/V6 4.8 kb mRNA is missing 988 nucleotides of contiguous coding and non-coding sequence at its 3' end resulting in an mRNA predicted to encode a truncated polypeptide missing three previously unrecognized potential COOH-proximal bipartite nuclear localization signals [Mirski, S. E. L., & Cole, S. P. C. (1995) Cancer Res. 55, 2129-2134]. We have now determined the structure of the larger 6.2 kb topoisomerase II alpha-related mRNA and show that it is missing 684 nucleotides of contiguous 3' coding and non-coding sequence between nucleotide positions 4267 and 4951. This sequence is replaced by 847 nucleotides of new sequence, containing an in-frame stop codon after 41 nucleotides. The translation product of the 6.2 kb mRNA is predicted to contain 13 new amino acids replacing the COOH-terminal 109 residues of wild-type topoisomerase II alpha, producing a truncated polypeptide of approximately 160 kDa. Immunoblot analyses using antisera against the unique COOH-terminal 13 and 34 amino acids encoded by H209/V6 6.2 kb and 4.8 kb mRNAs, respectively, confirmed that both mRNAs are translated. Restriction enzyme analysis and sequencing of the 3'-proximal region of the TOP2A gene in the H209 and H209/V6 DNA revealed that a partial deletion has occurred in H209/V6 and the novel sequence identified in the H209/V6 6.2 kb mRNA is derived from the adjacent 3' intron as a consequence of read-through at a concensus splice donor site. These observations suggest a mechanism for the generation of the two mutant topoisomerase II alpha mRNAs in H209/V6 cells and provide the first reported example of a drug resistant cell line containing two different cytoplasmic forms of topoisomerase II alpha.
Name Disambiguation in Anonymized Graphs using Network Embedding (2017)

In real-world, our DNA is unique but many people share names. This phenomenon often causes erroneous aggregation of documents of multiple persons who are namesake of one another. Such mistakes deteriorate the performance of document retrieval, web search, and more seriously, cause improper attribution of credit or blame in digital forensic. To resolve this issue, the name disambiguation task is designed which aims to partition the documents associated with a name reference such that each partition contains documents pertaining to a unique real-life person. Existing solutions to this task substantially rely on feature engineering, such as biographical feature extraction, or construction of auxiliary features from Wikipedia. However, for many scenarios, such features may be costly to obtain or unavailable due to the risk of privacy violation. In this work, we propose a novel name disambiguation method. Our proposed method is non-intrusive of privacy because instead of using attributes pertaining to a real-life person, our method leverages only relational data in the form of anonymized graphs. In the methodological aspect, the proposed method uses a novel representation learning model to embed each document in a low dimensional vector space where name disambiguation can be solved by a hierarchical agglomerative clustering algorithm. Our experimental results demonstrate that the proposed method is significantly better than the existing name disambiguation methods working in a similar setting.
Anti‐CD9 monoclonal antibody elicits staurosporine inhibitable phosphatidylinositol 4,5‐bisphosphate hydrolysis, phosphatidylinositol 3,4‐bisphosphate synthesis, and protein‐tyrosine phosphorylation in human platelets (1993)

Phosphoinositide metabolism elicited by anti-CD9 monoclonal antibody, a well-characterized platelet activator, was studied using acetylsalicylic acid-treated human platelets. TP82, which is an anti-CD9 monoclonal antibody, induced classical phosphatidylinositol 4,5-bisphosphate hydrolysis, as monitored by intracellular Ca2+ mobilization and phosphatidic acid production, and synthesis of phosphatidylinositol 3,4-bisphosphate, which is a major component of newly-described 3-phosphorylated inositol phospholipids produced during platelet activation. These changes were severely inhibited by 1 microM staurosporine, a potent, though non-selective, protein kinase inhibitor, which also abolished TP82 induction of tyrosine phosphorylation of multiple platelet proteins. Protein-tyrosine phosphorylation appears necessary to initiate both the classical phosphoinositide turnover and synthesis of the newly-described 3-phosphorylated inositol phospholipids in anti-CD9 monoclonal antibody-induced platelet activation.
Haplophytine. Novel type of indole alkaloid (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHaplophytine. Novel type of indole alkaloidPeter. Yates, F. N. MacLachlan, I. D. Rae, M. Rosenberger, A. G. Szabo, C. R. Willis, M. P. Cava, M. Behforouz, M. V. Lakshmikantham, and W. ZeigerCite this: J. Am. Chem. Soc. 1973, 95, 23, 7842–7850Publication Date (Print):November 1, 1973Publication History Published online1 May 2002Published inissue 1 November 1973https://pubs.acs.org/doi/10.1021/ja00804a046https://doi.org/10.1021/ja00804a046research-articleACS PublicationsRequest reuse permissionsArticle Views885Altmetric-Citations76LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Shannon capacity of frequency-overlapped digital subscriber loop channels (2003)

The Shannon capacity equation defines the total data transmission capacity of a transmission channel as a function of receiver SNR and bandwidth. When the frequency-overlapped (FO) duplex mode of operation with an echo canceller is implemented on a digital subscriber loop (DSL) channel, then the near-end receiver SNR that determines the inbound capacity is not only a function of the far-end transmitted signal power, but also of the residual near-end transmit signal power that leaks through the echo canceller. This 'coupling' occurs on both ends of the copper loop for upstream and downstream reception. Consequently, maximization of the data transmission capacity is a "bidirectional" problem. This problem has not been analyzed in the literature. We define the notion of the total bidirectional data capacity of a copper loop and formulate the maximum bidirectional capacity that can be achieved when a power budget is allocated to each of the two transmitters. We then compute the channel capacity by an integer linear programming (ILP) technique for various channel and noise conditions and also compare the results with the data rates that are obtained by a modified "water-filling" algorithm designed for FO duplex operation and with the channel capacities of the conventional frequency-division (FD) simplex transmission.
Ontogenetic expression of erythropoietin and hypoxia‐inducible factor‐1 alpha genes in subterranean blind mole rats (2004)

ABSTRACT Blind subterranean mole rats of the Spalax ehrenbergi superspecies in Israel have evolved multiple adaptive strategies to face underground hypoxia. Hypoxia‐inducible factor‐1α (HIF‐1α) and erythropoietin (Epo) are key factors in the development of normal erythropoiesis and angiogenesis. Here, we demonstrate via real‐time polymerase chain reaction (PCR) quantification that Spalax fetal liver and kidney express higher levels of Epo mRNA than Rattus , generating reinforcement of fetal erythropoiesis underground and adapting it to life underground in an atmosphere of abrupt and sharp fluctuations of O 2 supply. In neonates, Rattus liver and kidney express higher Epo levels than Spalax under both normoxia and hypoxia, probably due to Rattus ineffective erythropoiesis during embryonic life and its birth in a poorly ventilated breeding nest under ground. Adult Rattus kidney and liver, and adult Spalax liver express similar levels of Epo mRNA under normoxia and hypoxia. However, adult Spalax hypoxic kidney, the major site of erythropoietin production in adult mammals, shows levels that were twice as high as that of Rattus. Spalax expresses remarkably higher levels of HIF‐1α mRNA than Rattus at all developmental stages studied, which peaked in neonates, as an adaptation against hypoxia.