gebhart/patrepeval huggingface dataset:
Experimental investigation of anti-colliding pulse mode-locked semiconductor lasers (2015)

We experimentally demonstrate anti-colliding pulse mode-locking (ACPML) in an integrated semiconductor laser. The device geometry consists of a gain section and a saturable absorber (SA) section located immediately next to one of the cavity facets. After depositing a low-reflection coating on the SA facet and a high-reflection coating on the gain section facet, the threshold is unchanged, while the modulation of the SA is increased. The data presented here confirm that the ACPML configuration improves the peak output power of the pulses, reduces the amplitude fluctuation and timing jitter, and expands the biasing parameter range over which the stable mode-locking operation occurs.
Generalizing list scheduling for stochastic soft real-time parallel applications (2003)

Advanced architecture processors provide features such as caches and branch prediction that result in improved, but variable, execution time of software. Hard real-time systems require tasks to complete within timing constraints. Consequently, hard real-time systems are typically designed conservatively through the use of tasks' worst-case execution times (WCET) in order to compute deterministic schedules that guarantee task's execution within giving time constraints. This use of pessimistic execution time assumptions provides real-time guarantees at the cost of decreased performance and resource utilization. 
In soft real-time systems, however, meeting deadlines is not an absolute requirement (i.e., missing a few deadlines does not severely degrade system performance or cause catastrophic failure). In such systems, a guaranteed minimum probability of completing by the deadline is sufficient. Therefore, there is considerable latitude in such systems for improving resource utilization and performance as compared with hard real-time systems, through the use of more realistic execution time assumptions. 
Given probability distribution functions (PDFs) representing tasks' execution time requirements, and tasks' communication and precedence requirements, represented as a directed acyclic graph (DAG), this dissertation proposes and investigates algorithms for constructing non-preemptive stochastic schedules. New PDF manipulation operators developed in this dissertation are used to compute tasks' start and completion time PDFs during schedule construction. PDFs of the schedules' completion times are also computed and used to systematically trade the probability of meeting end-to-end deadlines for schedule length and jitter in task completion times. 
Because of the NP-hard nature of the non-preemptive DAG scheduling problem, the new stochastic scheduling algorithms extend traditional heuristic list scheduling and genetic list scheduling algorithms for DAGs by using PDFs instead of fixed time values for task execution requirements. The stochastic scheduling algorithms also account for delays caused by communication contention, typically ignored in prior DAG scheduling research. 
Extensive experimental results are used to demonstrate the efficacy of the new algorithms in constructing stochastic schedules. Results also show that through the use of the techniques developed in this dissertation, the probability of meeting deadlines can be usefully traded for performance and jitter in soft real-time systems.
A test suite for the calculation of time domain frequency stability (2002)

This paper describes a test suite to check the accuracy of frequency stability analysis software. It contains the values of several common statistics and frequency stability measures for two data sets, a small one suitable for manual entry, and a larger one produced by a portable pseudo-random number generator. The paper also discusses related issues such as data gaps and outliers, phase-frequency conversions, drift removal, numerical precision, plotting, and simulation.
Recruitment of Complement Factor H-Like Protein 1 Promotes Intracellular Invasion by Group A Streptococci (2003)

Numerous microbial pathogens exploit complement regulatory proteins such as factor H (FH) and factor H-like protein 1 (FHL-1) for immune evasion. Fba is an FHL-1 and FH binding protein expressed on the surface of the human pathogenic bacterium, Streptococcus pyogenes, a common agent of pharyngeal, skin, and soft-tissue infections. In the present study, we demonstrate that Fba and FHL-1 work in concert to promote invasion of epithelial cells by S. pyogenes. Fba fragments were expressed as recombinant proteins and assayed for binding of FHL-1 and FH by Western blotting, enzyme-linked immunosorbent assay, and surface plasmon resonance. A binding site for FHL-1 and FH was localized to the N-terminal half of Fba, a region predicted to contain a coiled-coil domain. Deletion of this coiled-coil domain greatly reduced FHL-1 and FH binding. PepSpot analyses identified a 16-amino-acid segment of Fba which overlaps the coiled-coil domain that binds both FHL-1 and FH. To localize the Fba binding site in FHL-1 and FH, surface plasmon resonance was used to assess the interactions between the streptococcal protein and a series of recombinant FH deletion constructs. The Fba binding site was localized to short consensus repeat 7 (SCR 7), a domain common to FHL-1 and FH. SCR 7 contains a heparin binding site, and heparin was found to inhibit FHL-1 binding to Fba. FHL-1 promoted entry of Fba(+) group A streptococci into epithelial cells in a dose-dependent manner but did not affect invasion by an isogenic fba mutant. To our knowledge, this is the first report of a bacterial pathogen exploiting a soluble complement regulatory protein for entry into host cells.
OPERATING EXPERIENCE OF LARGE CONTAINERSHIPS (1974)

This paper reminds the reader of the nature of the Europe-Far East Containership services, before going on to describe the actual cargoes and the performance of the gear. The behavior of the ships themselves, both as to seakeeping and as to structure, receives mention. An outline of the economic performance is given; some personnel aspects are highlighted; and three major incidents from operational experience are described.
Isolated lung perfusion with adriamycin. A preclinical study (1983)

Isolated in vivo single-lung perfusion with an Adriamycin-containing whole-blood perfusate was performed in three groups of dogs after establishing adequate controls. The procedure, performed through a left thoracotomy, was followed two weeks later by a contralateral pneumonectomy. Survival following pneumonectomy was used as the ultimate end point in assessing perfusion toxicity. Groups I and II had high mortality rates but provided valuable information concerning perfusion methods, venous drainage techniques, drug dosage schedules, and perfusate flow rates. The group III study consisted of five dogs perfused for 45 minutes at flow rates sufficient to maintain mean pulmonary artery pressure at 12-15 mm Hg. An initial Adriamycin (Adr) dosage of 0.5 micrograms/ml in the plasma perfusate resulted in mean peak Adr lung tissue levels of 3.8 +/- 1.06 micrograms/g. All animals survived right pneumonectomy 19 +/- 4 days later. Three dogs have been killed and histologic examination showed only mild focal pleural and subpleural interstitial fibrosis. Based on these studies it is concluded that isolated single-lung perfusion is a reproducibly safe technique and that a dosage of Adr has been identified which produces no apparent toxity in a large animal model. A clinical trial is currently in progress.
High absorptivity solar absorbing coatings (1974)

A high absorptivity is essential in the efficient use of a solar collector. In this paper we review some of the fundamental considerations in solar absorbing coatings and present reflectance data on several chemically treated surfaces which appear to be black in the solar spectrum. Reflectivity data are also presented for a lead sulfide “selective paint” which uses a silicone binder.
A survey of word embeddings for clinical text (2019)

Representing words as numerical vectors based on the contexts in which they appear has become the de facto method of analyzing text with machine learning. In this paper, we provide a guide for training these representations on clinical text data, using a survey of relevant research. Specifically, we discuss different types of word representations, clinical text corpora, available pre-trained clinical word vector embeddings, intrinsic and extrinsic evaluation, applications, and limitations of these approaches. This work can be used as a blueprint for clinicians and healthcare workers who may want to incorporate clinical text features in their own models and applications.
A survey of internal fuses for solid tantalum capacitors (2003)

Reasons for fusing solid tantalum capacitors are discussed, stressing that they are only required where there is a low series impedance and a high current availability and where a failed capacitor can overheat due to the fault power dissipation. The two main types of fuses which can be used, i.e. electrically or thermally actuated, are examined. The main advantage of an electrical version is more rapid operation while the advantage of a thermal fuse is lower resistance. As a rough guide the electrical fuse should operate when the fault current reaches 1 amp after 1 second but should survive the initial charging current, which can be tens or hundreds of amps for a very short period. The thermal fuse should prevent the body temperature from exceeding 300 degrees C.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Acoustic streaming induced by the “vortex whistle” is the cause of the Ranque-Hilsch effect (1982)

In 1933, Ranque discovered a striking phenomenon: When pressurized air is injected tangentially into a pipe and imparted a swirling motion, its total temperature separates into a colder one at the centerline and a warmer one at the periphery. The separation takes place spontaneously, without the aid of any external mechanical work. The effect became popularized after the Second World War by the work of Hilsch; the so-called Ranque-Hilsch tube or the vortex tube is now commercially available. Even for inlet air at only a few atmospheric pressure and at room temperature, the total temperature at the tube center can easily become freezingly cold; the total temperature at the periphery exceeds its upstream value correspondingly. Although there exists a general consensus that some unsteadiness is needed to account for this phenomenon, the crucial issue as to the precise form of unsteadiness or its explicit mechanism has never been resolved. Now, it is a known fact that a pure tone of high intensity or vortex whistle often emanates from the vortex flow, the Ranque-Hilsch tube included; its frequency increases proportionally to the swirl. We submit here that acoustic streaming induced by the vortex whistle is the mechanism of the Ranque-Hilsch effect. We demonstrate this, based on our recently published work [Kurosaka et al., J. Fluid Mech. (in print)] and on additional results obtained subsequently. [Work supported by the Air Force Office of Scientific Research.]
A Novel Accumulation Mode GAAC FinFET Transistor: Device Analysis, 3D TCAD Simulation and Fabrication (2009)

We report the analysis and TCAD results on gate-all-around cylindrical (GAAC) FinFET with operation based on channel accumulation. GAAC FinFETs operate in accumulation mode in which the current in accumulation is flowing across the whole cylinder-shaped Si body, have high mobility, reduced low-frequency noise and short-channel effects, increased the threshold voltage and avoid effects due to depletion of poly-Si gates. The Ion/Ioff ratio of the device can be larger than 10^6, a key parameter for device operation.
Web publishing unleashed : HTML, CGI, SGML, VRML Java (1996)

Includes sections on how to organize and plan your information, design pages, and become familiar with hypertext and hypermedia. Choose from a range of applications and technologies, including Java, SGML, VRML and the newest HTML and Netscape extensions. -- Teaches how to convey information on the Web using the latest technology -- including Java -- Readers learn how to Integrate multimedia and interactivity into their Web publications -- The CD-ROM contains software, templates and examples to help you become a successful Web publisher
Single-photon SPAD imagers in biophotonics: Review and Outlook (2019)

Single-photon avalanche diode (SPAD) arrays are solid-state detectors offering imaging capabilities at the level of individual photons, with unparalleled photon counting and time-resolved performance. This fascinating technology has progressed at very high pace in the past 15~years, since its inception in standard CMOS technology in 2003. A host of architectures has been explored, ranging from simpler implementations, based solely on off-chip data processing, to progressively ``smarter" sensors including on-chip, or even pixel-level, timestamping and processing capabilities. As the technology matured, a range of biophotonics applications has been explored, including (endoscopic) FLIM, (multi-beam multiphoton) FLIM-FRET, SPIM-FCS, super-resolution microscopy, time-resolved Raman, NIROT, and PET. We will review some representative sensors and their corresponding applications, including the most relevant challenges faced by chip designers and end-users. Finally, we will provide an outlook on the future of this fascinating technology.
Incidence of Neisseria gonorrhoeae isolates negative by Syva direct fluorescent-antibody test but positive by Gen-Probe accuprobe test in a sexually transmitted disease clinic population (1993)

To determine the accuracy of the Syva (Palo Alto, Calif.) direct fluorescent-antibody (DFA) test in comparison with the Gen-Probe (San Diego, Calif.) Accuprobe culture confirmation test, we tested 395 isolates of Neisseria gonorrhoeae from cultures obtained from patients attending a sexually transmitted disease clinic from 1 July 1991 through 30 June 1992. All isolates were tested for DFA reactivity with a polyclonal reagent (Difco Laboratories, Detroit, Mich.) and a monoclonal reagent (Syva, Inc., direct specimen test) and for specific molecular probe reactivity by the Gen-Probe Accuprobe culture confirmation test for N. gonorrhoeae. The 395 isolates gave positive results for the Gen-Probe culture confirmation test and the Difco polyclonal direct specimen test. However, 18 (4.6%) of the isolates were negative for N. gonorrhoeae by the Syva DFA test. With the exception of six beta-lactamase-positive isolates, all isolates that were negative by Syva DFA were sensitive to penicillin, tetracycline, spectinomycin, and ceftriaxone by disk-diffusion susceptibility testing. Auxotyping and serotyping studies indicated that strains negative by Syva DFA consisted of several variants. The frequency of N. gonorrhoeae isolates showing negative results by Syva DFA in this patient population ranged from 0 to 11.5%/month. Laboratories using only the Syva DFA test for confirmation of N. gonorrhoeae may incur a significant risk of misidentification.
P-type NaₓNi₀.₂₂Co₀.₁₁Mn₀.₆₆O₂ materials: linking synthesis with structure and electrochemical performance (2014)

P-type layered oxides are promising cathode materials for sodium-ion batteries and a wide variety of compounds have been investigated so far. Nevertheless, detailed studies on how to link synthesis temperature, structure and electrochemistry are still rare. Herein, we present a study on P-type NaₓNi₀.₂₂Co₀.₁₁Mn₀.₆₆O₂ materials, investigating the influence of synthesis temperature on their structure and electrochemical performance. The change of annealing temperature leads to various materials of different morphologies and either P3-type (700 °C), P3/P2-type (750 °C) or P2-type (800–900 °C) structure. Galvanostatic cycling of P3-type materials revealed high initial capacities but also a high capacity fade per cycle leading to a poor long-term cycling performance. In contrast, pure P2-type NaₓNi₀.₂₂Co₀.₁₁Mn₀.₆₆O₂, synthesized at 800 °C, exhibits lower initial capacities but a stable cycling performance, underlined by a good rate capability, high coulombic efficiencies and high average discharge capacity (117 mA h g⁻¹) and discharge voltage (3.30 V vs. Na/Na⁺) for 200 cycles.
Hydrogen-rich boron-containing materials for hydrogen storage (2008)

Hydrogen-rich boron-containing compounds have received extensive attention as potential hydrogen storage media for vehicular applications. The past years have seen significant progresses in material discovery, material composition/structure tailoring, catalyst identification and regeneration chemistry, which give rise to state-of-the-art hydrogen storage materials/technologies. Lithium tetrahydroborate-related materials exhibit the hitherto highest reversible hydrogen capacity via solid-gas reactions. Catalytic hydrolysis of sodium tetrahydroborate offers an on-demand hydrogen generation system for vehicular applications. Ammonia borane-related materials exhibit a satisfactory combination of material properties that are suited for on-board hydrogen sources, coupled with significant advances in spent fuels regeneration. This Perspective discusses the current progresses of these representative reversible or irreversible material systems, aiming at providing an outline of the forefront of hydrogen storage materials/technologies for transportation applications.
Expression of ΔF508 Cystic Fibrosis Transmembrane Regulator (CFTR) Decreases Membrane Sialylation (2009)

Chronic colonization and infection of the lung with Pseudomonas aeruginosa is a major cause of morbidity and mortality in cystic fibrosis (CF) patients. Imundo, et al. determined that CF cells had a higher concentration of an asialoganglioside (asialo-G(M1)), to which both P. aeruginosa and S. aureus bound preferentially. We sought to determine if the expression of mutant CFTR is associated with altered sialylation. Our study of epithelial cells transfected with normal and mutant DeltaF508 CFTR, the defect in the majority of CF patients in the United States, were analyzed by ELISA and FACS analysis of cell membranes labeled with lectins which bind to Neu5Ac. We determined that DeltaF508 CFTR is associated with decreased membrane sialic acid residues in the alpha2, 3 position and increased concentrations of asialo- G(M1). Quantitation of sialic acids released from the cellular membranes demonstrated that the presence of the DeltaF508 CFTR is associated with markedly decreased membrane sialylation, but similar cytoplasmic sialylation. Thus, DeltaF508 defect is correlated with decreased expression of G(M1) and with decreased sialylation of all cell surface structures, and this change occurs during post-translational modification of glycoproteins and glycolipids. This may be one factor involved in the chronic bacterial colonization seen in these patients.
Microwave‐accelerated preparation and analytical characterization of 5‐ethoxy‐<i>N</i>,<i>N</i>‐dialkyl‐[α,α,β,β‐H<sub>4</sub>]‐ and [α,α,β,β‐D<sub>4</sub>]‐tryptamines (2010)

The increased interest in N,N-dialkyl tryptamines is a reflection of their diverse range of biologically active properties. Deuterated derivatives are of interest for use as internal standards in bioanalytical or pharmacological assays. The present study reports on the synthesis of twelve novel 5-ethoxy-N,N-dialkyl-[α,α,β,β-H(4) ]-tryptamines and their [α,α,β,β-D(4) ]-counterparts following the Speeter and Anthony procedure. The normally time-consuming reduction step was carried out in 5 min under microwave-accelerated conditions. Good yields were obtained using tetrahydrofuran as the solvent at 150 °C. The resulting 24 tryptamines have been characterized by 1D/2D nuclear magnetic resonance spectroscopy and gas chromatography ion trap mass spectrometry. Differential fragmentation of side-chain-related iminium ions has been observed as a key principle. Because many N,N-dialkyltryptamines are available outside of traditional pharmaceutical supply chains as so-called 'research chemicals', the availability, as standards, of these new N,N-dialkyltryptamines will aid in identifiying novel tryptamines arising from these other souces. They should therefore be of immediate value within forensic, research, and public health contexts.
SSR Mode S downlink aircraft parameters validation and evaluation (2013)

Downlink Aircraft Parameters (DAPs) is one of Secondary Surveillance Radar (SSR) Mode S datalink functions. It enables a ground station to obtain real-time aircraft information such as selected altitude and ground speed. DAPs improves efficiency, capacity, and safety of Air Traffic Control (ATC) service. To employ DAPs for ATC service, the reliability of DAPs is important. However, some aircraft are transmitting wrong or erroneous DAPs data. Those data hinders the use of ATC service. In order to ensure the reliability of DAPs data, Electronic Navigation Research Institute (ENRI) developed a DAPs validation system. In the first phase of the development, two DAPs validation techniques are implemented. One technique is based on the methodologies developed by Massachusetts Institute of Technology (MIT) Lincoln Laboratory. The other technique uses tests to detect errors due to transmission problems. By using these techniques, we evaluated DAPs data collected at our experimental SSR mode S ground station. The results show that the proposed techniques can detect erroneous data, and enhance the reliability of DAPs.
Proposal of a Single-Transistor-Cell-Type Ferroelectric Memory Using an SOI Structure and Experimental Study on the Interference Problem in the Write Operation (1997)

A single-transistor-cell-type ferroelectric random access memory (FRAM) which consists of an array of metal-ferroelectric-semiconductor field effect transistors (MFSFETs) is proposed. In order to minimize the interference problem in the “write/read” operation, use of a silicon-on-insulator (SOI) structure is proposed, as well as optimizing the write and read methods partly using experimental results for ferroelectric capacitors. A key method for avoiding the interference problem is to generate a compensation pulse with a 1/3 amplitude and opposite polarity in the next timing to each write pulse. It is concluded from these considerations that the proposed structure is promising for use as a single-transistor-cell-type FRAM, if the electrical properties of a ferroelectric film on a Si substrate is as good as that on a Pt electrode.
Cloning and transcription analysis of the <i>Candida rugosa</i> propionyl‐CoA dehydrogenase gene and its expression in <i>Pichia pastoris</i> (2011)

The propionyl-CoA dehydrogenase (PACD) gene was cloned from Candida rugosa by the cDNA RACE technique. The full cDNA of the PACD gene has a length of 1408 bp, which contains a complete open reading frame (ORF) of 1329 bp, coding for 442 amino acids. The cDNA of PACD was cloned into the expression plasmid pPIC9K and transformed into Pichia pastoris GS115. The recombinant protein was purified by Ni-NTA affinity chromatography, and its size was observed to be approximately 49 kDa as estimated by SDS-PAGE. Anti-His antibodies were used to characterise the recombinant PACD by western-blot analysis. The recombinant protein retained the activity of catalysing propionyl-CoA to acryloyl-CoA. The results of dot-blotting hybridisation using a PACD cDNA probe indicated that the PACD mRNA level was modified at different stages: mRNA levels were low for the first 36 h, then increased through 48 h and eventually reached a stable level. These results indicate that propionate induction could significantly activate PACD mRNA expression. Information from this study will be helpful in elucidating the metabolic pathway for 3-hydroxypropionic acid production in C. rugosa.