gebhart/patrepeval huggingface dataset:
A Quality Improvement Framework for Equity in Cardiovascular Care: Results of a National Collaborative (2012)

Disparities in the quality of cardiovascular care provided to minorities have been well documented, but less is known about the use of quality improvement methods to eliminate these disparities. Measurement is also often impeded by a lack of reliable patient demographic data. The objective of this study was to assess the ability of hospitals with large minority populations to measure and improve the care rendered to Black and Hispanic patients. The Expecting Success: Excellence in Cardiac Care project utilized the standardized collection of self-reported patient race, ethnicity, and language data to generate stratified performance measures for cardiac care coupled with evidence-based practice tools in a national competitively selected sample of 10 hospitals with high cardiac volumes and largely minority patient populations. Main outcomes included changes in nationally recognized measures of acute myocardial infarction and heart failure quality of care and 2 composite measures, stratified by patient demographic characteristics. Quality improved significantly at 7 of the 10 hospitals as gauged by composite measures (p < .05), and improvements exceeded those observed nationally for all hospitals. Three of 10 hospitals found racial or ethnic disparities which were eliminated in the course of the project. Clinicians and institutions were able to join the standardized collection of self-reported patient demographic data to evidence-based measures and quality improvement tools to improve the care of minorities and eliminate disparities in care. This framework may be replicable to ensure equity in other clinical areas.
Inert Carbon Free Radicals. 14. Synthesis, Isolation, and Properties of Two Strongly π−π Interacting Mixed-Valence Compounds:  The Perchloro-4,4‘-ethynylenebis(triphenylmethyl) Anion Radical Potassium (18-Crown-6) Salt and the Perchloro-α,α,α‘,α‘-tetraphenyl-<i>p</i>-xylylene Anion Radical Tetrabutylammonium Salt (1997)

The perchloro-4,4‘-ethynylenebis(triphenylmethyl) anion radical (11) potassium 18-crown-6 salt and perchloro-α,α,α‘,α‘-tetraphenyl-p-xylylene anion radical (15) tetrabutylammonium salt have been isolated in pure form as solids perfectly stable in the air and moisture, withstanding temperatures up to 200 °C. Their physical and chemical properties have been studied using UV−vis, NIR, IR, ESR, cyclic voltammetry, magnetic susceptibility, and electrical conductivity and compared with other already reported and structurally related perchlorotriphenylmethyl systems in which an intramolecular “spin-charge exchange” takes place. In contrast with those compounds, the acetylene anion radical 11 shows an unusual band in the vis−NIR region (754 nm, 37.7 kcal/mol), not present in its corresponding biradical 10 and dianion 9, and the Thiele anion radical 15 shows a typical, but bathochromically shifted ca. 10 kcal/mol, radical band and an unusual NIR band at 1342 nm (21.2 kcal/mol) of high intensity. Application of Hush's theory of mixed-valence class III compounds to these unusual bands for PTM compounds, gives the values of ca. 18 and 10 kcal/mol for the resonance energy of 11 and 15 respectively. The close coincidence of these theoretical values with those obtained by comparing the UV−vis spectra of 11 and 15 with the PTM anion radical systems without resonance interaction can be regarded as a preliminary test of the validity of Hush's theory of organic mixed-valence class III compounds. The cyclic voltammograms of anion radicals 11 and 15 indicate that their precursors, the biradical 10 and perchloro-Thiele hydrocarbon 16 have suitable redox potentials as acceptor components of electrically conducting charge-transfer complexes. 11 and 15 present magnetic properties similar to those of PTM radicals, but as a consequence of the “spin charge resonance” they show a halving of the hyperfine coupling constants. More spectacular differences are shown in the electrical conductivity of 11 and 15 with values of 10-4 and 10-6 S cm-1, respectively, which can be a consequence of their molecular design as suggested the ΔE1/2 differences (6.4 vs 12 kcal/mol). These conductivity values are in the range of the corresponding TCNQ salts.
Photonic integration in a commercial scaled bulk-CMOS process (2009)

We demonstrate the first photonic chip designed for a commercial bulk CMOS process (65 nm-node) using standard process layers combined with post-processing, enabling dense photonic integration with high-performance microprocessor electronics.
The Activity Coefficients of Sulfuric Acid in Aqueous 2-Propanol Solutions at 25° (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Activity Coefficients of Sulfuric Acid in Aqueous 2-Propanol Solutions at 25°J. E. Land and H. D. CrockfordCite this: J. Am. Chem. Soc. 1950, 72, 5, 1895–1896Publication Date (Print):May 1, 1950Publication History Published online1 May 2002Published inissue 1 May 1950https://pubs.acs.org/doi/10.1021/ja01161a011https://doi.org/10.1021/ja01161a011research-articleACS PublicationsRequest reuse permissionsArticle Views37Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
69. Synthetic antimalarials. Part II. 2-Substituted-anilino-4-aminoalkylamino-6-methylpyrimidines (1946)

F. H. S. Curd, M. I. Davis and F. L. Rose, J. Chem. Soc., 1946, 351 DOI: 10.1039/JR9460000351
Upgrade Summer Severe Weather Tool (2011)

The goal of this task was to upgrade to the existing severe weather database by adding observations from the 2010 warm season, update the verification dataset with results from the 2010 warm season, use statistical logistic regression analysis on the database and develop a new forecast tool. The AMU analyzed 7 stability parameters that showed the possibility of providing guidance in forecasting severe weather, calculated verification statistics for the Total Threat Score (TTS), and calculated warm season verification statistics for the 2010 season. The AMU also performed statistical logistic regression analysis on the 22-year severe weather database. The results indicated that the logistic regression equation did not show an increase in skill over the previously developed TTS. The equation showed less accuracy than TTS at predicting severe weather, little ability to distinguish between severe and non-severe weather days, and worse standard categorical accuracy measures and skill scores over TTS.
The central philosophy of ancient India (1993)

(1993). The central philosophy of ancient India. Asian Philosophy: Vol. 3, No. 2, pp. 89-93.
Calculations of Combined Radiation and Convection Heat Transfer in Rod Bundles Under Emergency Cooling Conditions (1976)

A model has been developed to calculate the heat transfer coefficients from the fuel rods to the steam-droplet mixture typical of Boiling Water Reactors under Emergency Core Cooling System (ECCS) operation conditions during a postulated loss-of-coolant accident. The model includes the heat transfer by convection to the vapor, the radiation from the surfaces to both the water droplets and the vapor, and the effects of droplet evaporation. The combined convection and radiation heat transfer coefficient can be evaluated with respect to the characteristic droplet size. Calculations of the heat transfer coefficient based on the droplet sizes obtained from the existing literature are consistent with those determined empirically from the Full-Length-Emergency-Cooling-Heat-Transfer (FLECHT) program. The present model can also be used to assess the effects of geometrical distortions (or deviations from nominal dimensions) on the heat transfer to the cooling medium in a rod bundle.
Environmental assessment of present and future marine fuels (2014)

Our globalised world is connected by shipping, an industry powered by one of heaviest and dirtiest products of refining: heavy fuel oil. Tougher environmental regulations are now challenging the industry to take action. Ship-owners and operators are faced with the choice of installing exhaust gas cleaning technologies or switching to a different fuel altogether. The primary purpose of this thesis was to assess the environmental performance of present and future marine fuels and to evaluate potential methods and tools for their assessment.Two different system approaches are used in this study: life cycle assessment (LCA) and global energy systems modelling. LCA is a well-established method for assessing the environmental performance of fuels. This type of assessment was complemented with the use of the Global Energy Transition (GET) model to investigate cost-effective fuel choices based on a global stabilisation of CO2 emissions and the global competition for primary energy sources. The GET model includes all energy sectors and considers the interactions among them, but it is limited in scope to CO2 emissions and costs. The LCAs involve a holistic systems perspective that includes the entire life cycle and various types of environmental impacts, but they are limited to analyses of one product or service at a time. These methods provide insights that are both contradictory and complementary.This study concludes that there is substantial potential for reducing the environmental impact of shipping through a change in fuel types and/or the use of exhaust abatement technologies. A switch from heavy fuel oil to any of the alternatives investigated in this study reduces the overall environmental impact of marine fuels. The GET model indicates that it is cost-effective to phase out the use of crude oil-based fuels in the shipping sector and replace these fuels with the use of natural gas-based fuels during the next few decades. Based on the LCA results, the use of biofuels may be one possible way to reduce the impact of shipping on the climate, but biofuels may only be a cost-effective fuel in shipping if the corresponding annual available bioenergy resources are sufficiently large. Three important implications are highlighted: the importance of reducing the NOX emissions from marine engines, the need to regulate the methane slip from gas engines and the fact that a change in fuels may not reduce the impact of shipping on the climate.
Combination of Accumulated Motion and Color Segmentation for Human Activity Analysis (2008)

The automated analysis of activity in digital multimedia, and especially video, is gaining more and more importance due to the evolution of higher-level video processing systems and the development of relevant applications such as surveillance and sports. This paper presents a novel algorithm for the recognition and classification of human activities, which employs motion and color characteristics in a complementary manner, so as to extract the most information from both sources, and overcome their individual limitations. The proposed method accumulates the flow estimates in a video, and extracts Ã¢Â€Âœregions of activityÃ¢Â€Â by processing their higher-order statistics. The shape of these activity areas can be used for the classification of the human activities and events taking place in a video and the subsequent extraction of higher-level semantics. Color segmentation of the active and static areas of each video frame is performed to complement this information. The color layers in the activity and background areas are compared using the earth mover's distance, in order to achieve accurate object segmentation. Thus, unlike much existing work on human activity analysis, the proposed approach is based on general color and motion processing methods, and not on specific models of the human body and its kinematics. The combined use of color and motion information increases the method robustness to illumination variations and measurement noise. Consequently, the proposed approach can lead to higher-level information about human activities, but its applicability is not limited to specific human actions. We present experiments with various real video sequences, from sports and surveillance domains, to demonstrate the effectiveness of our approach.
[Ethyl esters of N-amidinobenzoyl aminoacids: inhibitory effect on thrombin, blood coagulation and platelet aggregation]. (1987)

In a previous paper we described the synthesis and the antiproteolytic activity of N-(3- and N-(4-amidinobenzoyl)-L-amino acids. As an extension of these studies we examined the possible inhibitory effect of these compounds on thrombin, blood coagulation and platelet aggregation. Values of Ki for the binding to thrombin are independent of the nature of the amino acids side chain and superimposable with those obtained for the formation of benzamidine-thrombin adduct. These data suggest slight effect on blood coagulation. The benzamidine derivatives are more active on platelets.
Lysosomal Storage Diseases of Animals: An Essay in Comparative Pathology (1997)

A wide variety of inherited lysosomal hydrolase deficiencies have been reported in animals and are characterized by accumulation of sphingolipids, glycolipids, oligosaccharides, or mucopolysaccharides within lysosomes. Inhibitors of a lysosomal hydrolase, e.g., swainsonine, may also induce storage disease. Another group of lysosomal storage diseases, the ceroid-lipofuscinoses, involve the accumulation of hydrophobic proteins, but their pathogenesis is unclear. Some of these diseases are of veterinary importance, and those caused by a hydrolase deficiency can be controlled by detection of heterozygotes through the gene dosage phenomenon or by molecular genetic techniques. Other of these diseases are important to biomedical research either as models of the analogous human disease and/or through their ability to help elucidate specific aspects of cell biology. Some of these models have been used to explore possible therapeutic strategies and to define their limitations and expectations.
New synthesis of 1,4,8,11-tetraazacyclotetradecane (Cyclam) via the nickel(II) complex (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew synthesis of 1,4,8,11-tetraazacyclotetradecane (Cyclam) via the nickel(II) complexE. Kent BarefieldCite this: Inorg. Chem. 1972, 11, 9, 2273–2274Publication Date (Print):September 1, 1972Publication History Published online1 May 2002Published inissue 1 September 1972https://pubs.acs.org/doi/10.1021/ic50115a065https://doi.org/10.1021/ic50115a065research-articleACS PublicationsRequest reuse permissionsArticle Views2051Altmetric-Citations71LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
One-Pot Synthesis of Symmetrical and Unsymmetrical Bisarylethynes by a Modification of the Sonogashira Coupling Reaction (2002)

A modification of the Sonogoshira coupling reaction employing an amidine base and a substoichiometric amount of water generates symmetrical and unsymmetrical bisarylethynylenes in one pot through in situ deprotection of trimethylsilylethynylene-added intermediates.
Self-sustained intensity oscillation of a laser diode introduced by a delayed electrical feedback using an optical fiber and an electrical amplifier (1981)

A self-sustained oscillation of laser light intensity emitted by a laser diode was newly observed by a delayed network using an optical fiber and an electrical feedback system. The time delay (transit time) of the light beam through the optical fiber plus the time delay of the electrical signal in the electrical feedback system determines the oscillation frequency of the light intensity. The oscillation for the fiber length of 7 km was obtained by using an electrical amplifier with large gain. With a wide-band amplifier, harmonic (multimode) oscillations took place where the waveform was almost square.
The HIV-1 Rev/RRE system is required for HIV-1 5' UTR cis elements to augment encapsidation of heterologous RNA into HIV-1 viral particles (2011)

Premised on encapsidation of a heterologous RNA into HIV-1 viral particles, our findings define a functional HIV-1 packaging system as comprising the 5' UTR cis elements, Gag, and the Rev/RRE system, in which the Rev/RRE system is required to make the RNA amenable to the ensuing interaction between Gag and the canonical packaging signal for subsequent encapsidation.
Identification of a genetically distinct subspecies of Mycobacterium kansasii (1992)

To assess the usefulness of a specific DNA probe for Mycobacterium kansasii, 105 isolates from Australia, Belgium, Japan, South Africa, and Switzerland were collected and analyzed. Twenty of these isolates were probe negative, of which 18 were from Belgium and Switzerland. Analysis of all isolates by Southern blot hybridization indicated a lack of variability among probe-positive isolates, while probe-negative isolates were clearly distinct and showed greater diversity. Sequence analysis of the 250 nucleotides at the 5' end of the 16S rRNA gene revealed that 19 of the 20 probe-negative isolates had a sequence different from that of M. kansasii. A total of five nucleotide differences were present in a cluster consisting of two nucleotide deletions and three nucleotide substitutions. These results suggest the existence of a genetic subspecies of M. kansasii.
Structural studies of some multiply bonded diruthenium tetracarboxylate compounds (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructural studies of some multiply bonded diruthenium tetracarboxylate compoundsAvi Bino, F. Albert Cotton, and Timothy R. FelthouseCite this: Inorg. Chem. 1979, 18, 9, 2599–2604Publication Date (Print):September 1, 1979Publication History Published online1 May 2002Published inissue 1 September 1979https://pubs.acs.org/doi/10.1021/ic50199a052https://doi.org/10.1021/ic50199a052research-articleACS PublicationsRequest reuse permissionsArticle Views721Altmetric-Citations110LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Cellular localization of simian immunodeficiency virus in lymphoid tissues. I. Immunohistochemistry and electron microscopy. (1989)

Simian immunodeficiency virus (SIV) is a lentivirus with genetic relatedness to the human immunodeficiency viruses (HIV-1 and HIV-2). It induces a fatal syndrome in rhesus monkeys that closely parallels the clinical course of AIDS in humans. The authors used double-labeling immunohistochemical procedures on rhesus lymph node and spleen taken during different time periods after SIV infection to localize the p27 gag protein to specific cellular immunophenotypes. In animals with follicular hyperplasia, viral protein was found associated predominantly with follicular dendritic cells. Many of these cells showed ultrastructural alterations consisting of swollen dendritic processes containing electron-dense material. Lentiviral particles were found associated with this cell type only rarely. In lymphoid tissues with other histopathologic changes, macrophages and multinucleate giant cells were the predominant cell types containing detectable quantities of viral protein; smaller numbers of p27+ lymphocytes were present. Ultrastructurally, viral particles were found within the extracellular space adjacent to tissue macrophages and within membrane-bound vacuoles of giant cells and tissue macrophages. These results show that certain histologic patterns seen during the course of infection correlate with the localization of viral antigen to specific cellular immunophenotypes and that during the disease course, viral protein is preferentially localized in sections of lymph node and spleen to cells of the macrophage and dendritic cell lineages.
Development of an agar-methyl cellulose clonogenic assay for cells in transitional cell carcinoma of the human bladder. (1979)

We report the development of a clonogenic assay for progenitor cells in transitional cell carcinoma of the bladder. Colony growth has been demonstrated from cells obtained both from surgical biopsies and from bladder barbotages. Electron microscopic and karyotypic evidence supports the contention that these progenitors represent a part of the population maintaining the tumor in vivo. Colony growth occurred in 9 of 11 surgical biopsy samples and in 6 of 6 bladder barbotage samples. Plating efficiency ranged up to 0.7%, and colony size was in some instances greater than 1000 cells. The assay appears potentially useful for analysis of the biology of human transitional cell carcinoma.