gebhart/patrepeval huggingface dataset:
New delay-integration method for resolving individual components of a pair of composite signals (2007)

Many scientific measurements are actually a composite of two or more indirectly measured values. A distance measurement, for example, is actually a measurement of the true distance and some amount of error added together. A new method for decomposing a pair of such composite signals into their individual components in certain situations is described. The method utilizes a delay time difference between the components in each of the two composite signals to provide information necessary to reconstruct the individual components. This decomposition would allow for the possible removal of one of the components, such as in the case of unwanted noise. The method is able to distinguish between two signals with similar frequencies and amplitudes, making it a viable solution in situations where simple low- or high-pass filtering would remove needed signal information. Three successful applications of the method are described, including measurement of lateral tape motion (LTM) in a magnetic data storage tape drive and removal of additive noise from both an electrical and a mechanical system.
A Multi-VC Dynamically Shared Buffer with Prefetch for Network on Chip (2012)

In this paper, we propose a novel multi-VC dynamically shared buffer named DAMQ-PF for network on chip to decrease the memory and area requirement of statically allocating shared buffer among multiple virtual channels (VC). A small prefetch buffer is used for each VC to store data read from the shared buffer in advance. The same mechanism is also used in the implementation of idle address list. By so doing, we implement continuous and concurrent reading and writing of the shared buffer without delay. A fair credit management method is also proposed to avoid a single VC occupying the shared buffer exclusively. Analyses and tests show that DAMQ-PF achieves high buffer utilization, low write and read delay and high throughput which satisfies the performance requirement of NoC based on flit switch very well.
Personalized Attraction Recommendation System for Tourists Through Check-In Data (2017)

Online social networks now play a prominent role in our daily lives and our decisions and behaviors in many areas. Of particular interest here is the application of social network data to give users access to tourist information. There is a growing need for information on tourism and tourist activities to satisfy user queries in this domain. Social networks, such as Facebook, Twitter, and Foursquare, among others, store substantial volumes of check-in data, which are a valuable resource for recommending tourism attractions. However, using Facebook check-in data has rarely been considered in conventional recommendation systems (RSs). This presents not only a new research challenge for the computer science and information technology fields but also an interesting opportunity for the tourism industry: knowing what kind of attractions tourists are interested in and how to acquire their user preferences without adding tasks to users of an RS. We propose a tourism RS that is based on its recommendations on data dynamically aggregated and extrapolated from the Facebook check-in data. In addition, the so-called “cold-start”problem has been resolved by using users' Friends' check-in data to analyze ongoing Facebook activity and update user profiles in the system. Most Facebook users have a well-extended list of Friends. Consequently, the proposed system can dynamically learn user behavior and appropriately adapt recommendations. This paper demonstrate the usefulness of the data available on Facebook through the example studies involving attraction recommendations, resolving the cold-start problem, and adapting the user model to improve recommendation quality in the tourism domain.
Loop optimization for a class of memory-constrained computations (2001)

Compute-intensive multi-dimensional summations that involve products of several arrays arise in the modeling of electronic structure of materials. Sometimes several alternative formulations of a computation, representing different space-time trade-offs, are possible. By computing and storing some intermediate arrays, reduction of the number of arithmetic operations is possible, but the size of intermediate temporary arrays may be prohibitively large. Loop fusion can be applied to reduce memory requirements, but that could impede effective tiling to minimize memory access costs. This paper develops an integrated model combining loop tiling for enhancing data reuse, and loop fusion for reduction of memory for intermediate temporary arrays. An algorithm is presented that addresses the selection of tile sizes and choice of loops for fusion, with the objective of minimizing cache misses while keeping the total memory usage within a given limit. Experimental results are reported that demonstrate the effectiveness of the combined loop tiling and fusion transformations performed by using the developed framework.
Feasibility of Treating Prehypertension with an Angiotensin-Receptor Blocker (2006)

Over a period of four years, stage 1 hypertension developed in nearly two thirds of patients with untreated prehypertension (the placebo group). Treatment of prehypertension with candesartan appeared to be well tolerated and reduced the risk of incident hypertension during the study period. Thus, treatment of prehypertension appears to be feasible. (ClinicalTrials.gov number, NCT00227318.).
Development of an optical 2-axis force sensor usable in MRI environments (2003)

This paper presents a MR compatible force sensor. Recently, MRI are widely used in various fields, from medical purpose to brain science, and simultaneous measurement of force information enables more precise investigations of obtained images of living tissue. However, conventional metal force sensors which contaminate the true signals of MRI cannot be used in MRI environments. Furthermore, present MR compatible force sensors have limitation in accuracy, dynamic range and multi axis sensibility. In this paper, an optical 2-axis force sensor without any metal and electronic components in the sensing element is developed with photo sensors and optical fibers.
Variable Cycle Powerplants for a Mach 2.7 Supersonic Civil Transport (1996)

The aim of the work outlined in this paper is to compare three different variable cycle jet engine concepts for future SSTs. These engines are: the Turbofan-Turbojet, the Mid-Tandem Fan engine and the Double Bypass Engine. The comparison is carried out on a basis of performance, handling and sizing issues. This preliminary analysis compares S.F.C., size, variable geometry and cycle changes, and the effect of variable stator on the running lines of each compressor for each engine. The fuel bill, for two standard missions, is estimated as well. These preliminary results indicate that the three engines are quite similar in terms of general suitability. The Mid Tandem Fan appears to be an attractive proposition from the point of view of sizing, however this comes with a small penalty in fuel consumption.
Memory T-cells and characterization of peripheral T-cell clones in acute Kawasaki disease (2010)

Kawasaki disease (KD) is a pediatric self-limited vasculitis characterized by immune-mediated destruction of the arterial wall and myocardium. Neither the trigger that incites the inflammation nor the switch that turns it off is known. To further our understanding of KD pathogenesis and the role of regulatory T-cells in modulating the inflammatory response, we studied circulating effector memory T-cells (CCR7- and IL-15+ T(em)) and central memory T-cells (CCR7+ and IL-15+ T(cm)) in six KD subjects. In two of the subjects, we cloned the remaining T-cell population by limiting dilution. TaqMan analysis of T(em) studied in two KD subjects suggested that T(em) are pro-inflammatory CD4+T-helper 1 cells and CD8+ cytotoxic T-cells. Following memory T-cells over time, we defined that circulating T(em) and T(cm) are detectable during the acute phase in some KD subjects before treatment with intravenous immunoglobulin. Both T(em) and T(cm) expand rapidly within 2 weeks of treatment. The circulating T(em) pool contracts, while T(cm) further proliferate in the convalescent phase. Following depletion of memory T-cells, numerous T-cell clones were derived from two acute KD subjects. The large majority of these T-cells displayed the functional phenotype of peripherally induced regulatory T-cells (T(reg)). These findings provide insight into the nature and kinetics of the adaptive immune response in KD.
Effect of Tesamorelin on Visceral Fat and Liver Fat in HIV-Infected Patients With Abdominal Fat Accumulation (2014)

clinicaltrials.gov Identifier: NCT01263717.
Lymphocyte‐Endothelial Interactions in Inflamed Synovia:Involvement of Several Adhesion Molecules and Integrin Epitopes (1993)

The role of several adhesion molecules for lymphocyte-endothelial interactions in the synovia of rheumatoid arthritis patients was studied using the frozen section assay. Partial inhibition of lymphocyte binding to endothelium of synovial sections could be observed with antibodies against CD44, L-selectin, and beta 1- and beta 2-integrins, pointing to the participation of several adhesion molecules in the regulation of lymphocyte immigration into inflamed synovia rather than the presence of a unique homing receptor. Different degrees of inhibition were found within a series of antibodies against alpha 4- and beta 1-integrins known to have functional effects in other interaction systems. In addition, increased binding to endothelial cells was induced when lymphocytes were pretreated with TS2/16 anti-beta 1 IgG, whereas binding to non-endothelial components of synovia was increased after treatment with HP 2/4 (anti-alpha 4) Fab. The data suggest a multifunctional role of alpha 4/beta 1-integrins in directly mediating adhesion as well as regulating adhesive interactions in the rheumatoid synovia.
Synthesis of N-vinylacetamide and preparation of some polymers and copolymers (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of N-vinylacetamide and preparation of some polymers and copolymersRobert W. Stackman and Richard H. SummervilleCite this: Ind. Eng. Chem. Prod. Res. Dev. 1985, 24, 2, 242–246Publication Date (Print):June 1, 1985Publication History Published online1 May 2002Published inissue 1 June 1985https://pubs.acs.org/doi/10.1021/i300018a014https://doi.org/10.1021/i300018a014research-articleACS PublicationsRequest reuse permissionsArticle Views442Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Randomized, Double-Blind Study of the Safety, Tolerability, and Efficacy of Tafenoquine versus Mefloquine for Malaria Prophylaxis in Nonimmune Subjects (2009)

This study represents the first phase III trial of the safety, tolerability, and effectiveness of tafenoquine for malaria prophylaxis. In a randomized (3:1), double-blinded study, Australian soldiers received weekly malaria prophylaxis with 200 mg tafenoquine (492 subjects) or 250 mg mefloquine (162 subjects) for 6 months on a peacekeeping deployment to East Timor. After returning to Australia, tafenoquine-receiving subjects received a placebo and mefloquine-receiving subjects received 30 mg primaquine daily for 14 days. There were no clinically significant differences between hematological and biochemical parameters of the treatment groups. Treatment-related adverse events for the two groups were similar (tafenoquine, 13.4%; mefloquine, 11.7%). Three subjects on tafenoquine (0.6%) and none on mefloquine discontinued prophylaxis because of possible drug-related adverse events. No diagnoses of malaria occurred for either group during deployment, but 4 cases (0.9%) and 1 case (0.7%) of Plasmodium vivax infection occurred among the tafenoquine and mefloquine groups, respectively, up to 20 weeks after discontinuation of medication. In a subset of subjects recruited for detailed safety assessments, treatment-related mild vortex keratopathy was detected in 93% (69 of 74) of tafenoquine subjects but none of the 21 mefloquine subjects. The vortex keratopathy was not associated with any effect on visual acuity and was fully resolved in all subjects by 1 year. Tafenoquine appears to be safe and well tolerated as malaria prophylaxis. Although the volunteers' precise exposure to malaria could not be proven in this study, tafenoquine appears to be a highly efficacious drug for malaria prophylaxis.
Glucose regulation of glutaminolysis and its role in insulin secretion. (1999)

Leucine or the nonmetabolized leucine analog +/- 2-amino-2-norbornane-carboxylic acid (BCH) (both at 10 mmol/l) induced biphasic insulin secretion in the presence of 2 mmol/l glutamine (Q2) in cultured mouse islets pretreated for 40 min without glucose but with Q2 present. The beta-cell response consisted of an initial peak of 20- to 25-fold above basal and a less marked secondary phase. However, BCH produced only a delayed response, while leucine was totally ineffective when islets were pretreated with 25 mmol/l glucose plus Q2. With Q2, 10 mmol/l BCH or leucine caused a nearly threefold increase, a twofold increase, or had no effect on cytosolic Ca2+ levels in islets pretreated for 40 min with 0, 5, or 15 mmol/l glucose, respectively. Thus, pretreatment of islets with high glucose inhibited BCH- and leucine-induced cytosolic Ca2+ changes and insulin release. Glucose decreased glutamine oxidation in cultured rat islets when BCH was present at 10 mmol/l, but not in its absence, with a lowest effective level of approximately 0.1 mmol/l, a maximum of 18-30 mmol/l, and an inhibitory concentration, 50%, of approximately 3 mmol/l. The data are consistent with the hypothesis that glucose inhibits glutaminolysis in pancreatic beta-cells in a concentration-dependent manner and hence blocks leucine-stimulated insulin secretion. We postulate that in the basal interprandial state, glutaminolysis of beta-cells is partly turned on because glutamate dehydrogenase (GDH) is activated by a decreased P-potential due to partial fuel depletion and sensitization to endogenous activators such as leucine. Additionally, it may contribute significantly to basal insulin release, which is known to be responsible for about half of the insulin released daily. The data explain "leucine-hypersensitivity" of beta-cells during hypoglycemia and contribute to the elucidation of the GDH-linked syndrome of hyperinsulinism associated with elevated serum ammonia levels. Thus, understanding the precise regulation and role of beta-cell glutaminolysis is probably central to our concept of normal blood glucose control.
Delineating Ebola entry (2015)

A specific calcium channel is required for Ebola virus to infect a cell [Also see Report by Sakurai et al. ]
An optimized active interphase transformer for auto-connected 12-pulse rectifiers results in clean input power (2002)

This paper proposes an optimized 12-pulse diode/SCR rectifier topology with lower kVA magnetics and fewer component count. The proposed system consists of an autotransformer (0.18 P/sub a/), two diode/SCR rectifier bridges and a new active interphase transformer. The new active interphase transformer combines the function of two zero sequence blocking transformers (ZSBT), and a conventional interphase transformer into one component wound on the same core. Further, an additional auxiliary winding is added on to the same core to facilitate active current shaping or input current for clean input power. A low kVA two-switch PWM-VSI is employed to control the auxiliary winding current to realize near sinusoidal utility line currents under varying load condition. The proposed system is suitable for the utility interface of high power AC motor drive systems to meet the current IEEE-519 harmonic current limits. The proposed system is very rugged and, in the event the active control were to fail, the system reverts to 12-pulse operation with 5th and 7th harmonics cancellation. Further the active PWM unit is of low kVA (0.15P/sub 0/) and is not directly exposed to line transients. Analysis and design of the proposed system is examined in detail and simulation results are shown.
Gigahertz Analog Repeater for Fiber Optic Delay Lines (1982)

A gigahertz analog fiber optic repeater is used to extend the achievable delay time for radar delay line applications. The repeater consists of a silicon avalanche photodiode (APD), a wide-band amplifier, and a GaAlAs laser diode transmitter. This repeater has an optical gain of 14.5 dB, a 42 dB electrical dynamic range, and a noise figure of approximately 6.5 dB. The frequency response is flat within +-2 dB over the frequency range from 10 MHz to 1.3 GHz. The nanosecond pulse fidelity is such that the subtraction between input and output pulses is 20 dB below the pulse amplitude.
Ultrafast time resolution in scanned probe microscopies (1990)

The speed limitations conventionally encountered in scanning tunneling microscopy, scanning capacitance microscopy, and atomic force microscopy result from the external electronics and are not inherent to the techniques themselves. Ultrafast time resolution faster than the bandwidth of the measuring electronics can be achieved by combining these techniques with picosecond optical excitation and utilizing inherent nonlinearities in the physical system. We demonstrate this idea by directly measuring carrier relaxation times at the Si(111)-(7×7) surface on the nanosecond time scale via scanning capacitance microscopy measurements of the surface photovoltage.
Cytotoxic Naphthoquinone and Azaanthraquinone Derivatives from an Endophytic <i>Fusarium solani</i> (2017)

Bioactivity-guided fractionation of the ethyl acetate extract obtained from the culture of the endophytic fungus Fusarium solani resulted in the isolation of one new naphthoquinone, 9-desmethylherbarine (1), and two azaanthraquinone derivatives, 7-desmethylscorpinone (2) and 7-desmethyl-6-methylbostrycoidin (3), along with four known compounds. Their structures were elucidated by spectral analysis, as well as a direct comparison of spectral data with those of known compounds. Azaanthraquinones 2 and 3 showed cytotoxic activity against four human tumor cell lines, MDA MB 231, MIA PaCa2, HeLa, and NCI H1975. A molecular docking study suggested DNA interactions as the mode of action of these naphthoquinones and azaanthraquinones.
Differences in Design Considerations between InGaN and Conventional High-Brightness Light-Emitting Diodes (1998)

Based on the escape cone concepts, high-brightness light-emitting diodes (LEDs) have been analyzed. In AlGaAs or InGaAlP LEDs, photon absorption in the ohmic region under the electrode is known to be significant. Thus, ins general, a thick window layer (WL) and a transparent substrate (TS) would minimize photon shielding by the electrodes and considerably improve photon output coupling efficiency. However, the schemes do not seem to be necessary in InGaN system. Photon absorption in ohmic contact to a wide bandgap semiconductor such as GaN may be negligible and, as a result, the significant photon shielding by the electrodes will not degrade the photon output coupling efficiency so much. The photon output coupling efficiency estimated in InGaN LEDs is about 2.5 - 2.8 times that of the conventional high-brightness LED structures based on both WL and TS schemes. As a result, the extenal quantum efficiency in InGaN LEDs is as high as 9% despite the presumably very low internal quantum efficiency.
The SCM/WDM system model for radio over fiber communication link (2008)

Subcarrier Multiplexing (SCM) is multiple radio frequency (RF) carrying signal to transmit through optical fiber using single wavelength. The most significant advantage of SCM in optical communications is its ability to place different optical carriers together closely. On the other hand, Wavelength Division Multiplexing (WDM) is a multiplexer at the transmitter to join the signals together, and a demultiplexer at the receiver to split them apart. In WDM each laser is modulated at a given speed, and the total aggregate capacity being transmitted along the high-bandwidth fiber is the sum total of the bit rates of the individual lasers. In this work, we investigate various issues in this scenario in order to provide a cost-effective, high performance solution for high speed data rates by the available bandwidth of the electrical and optical components. Therefore, SCM must be used in conjunction with WDM to utilize any significant fraction of the fiber bandwidth. The results is present higher bandwidth for long distance communication system (SMF, 150 km) by using SCM/WDM for Radio over Fiber. Therefore, the efficiency of bandwidth utilization of SCM is expected to be much better than conventional optical WDM.
Ice‐Templating of Core/Shell Microgel Fibers through ‘Bricks‐and‐Mortar’ Assembly** (2007)

A ‘bricks-and-mortar’ assembly approach can be used to create well- defined fibers on the microscale with alternating organic-inorganic arrangement through a simple ice-templating strategy. The fibers are constructed from closely packed monodisperse inorganic nanoparticles@PNIPAm core/shell microgels. A series of functional ‘bricks’, such as core/shell and hollow nanoparticles are prepared.
Three-Dimensional Computer Reconstruction from Surface Contours for Head CT Examinations (1981)

A three-dimensional surface reconstruction algorithm based on contour information from anatomic sites as identified on computed tomography examinations is presented. This algorithm efficiently reconstructs the surfaces between the contours using a triangular "tiling" method. A three-dimensional perspective view of the reconstructed surfaces is provided by a gray scale cathode-ray tube computer graphics system. Volume and surface area estimations are provided as a direct results of the surface reconstruction algorithm. Three cases are presented to illustrate the three-dimensional surface reconstruction algorithm.
Current issues in confidentiality: Computerized information systems, medical records, and patient rights (1986)

article Free Access Share on Current issues in confidentiality: Computerized information systems, medical records, and patient rights Author: Patricia T Fletcher View Profile Authors Info & Claims ACM SIGCAS Computers and SocietyVolume 16Issue 2-3Summer/Fall 1986 pp 8–18https://doi.org/10.1145/15483.15485Published:01 August 1986Publication History 3citation795DownloadsMetricsTotal Citations3Total Downloads795Last 12 Months15Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF