gebhart/patrepeval huggingface dataset:
e-Monitoring of Asthma Therapy to Improve Compliance in children using a real-time medication monitoring system (RTMM): the e-MATIC study protocol (2013)

Netherlands Trial Register NTR2583.
Post combustion CO2 capture with an amino acid salt (2011)

Amino acid salts are of great interest as potential solvents for CO2 capture because they are considered to be environmentally friendly. In the present paper, results of experimental work with a pilot plant with 3.5 M potassium sarcosine are presented. Both absorption kinetics and energy consumption are studied. The results show clearly that the amino acid salt system has a high absorption rate and high energy requirement compared to 30 wt-% MEA. The solvent system has been modeled in an in-house tool and simulation results are compared with the some performance results obtained experimentally. The soft-model approach developed for the potassium sarcosine solvent systems represents the absorber fairly well, while it seems to be too simplified to represent the stripper conditions. The present study is part of an ongoing EU project, Cesar.
Histone Deacetylase 3 Is Required for T Cell Maturation (2015)

Recent thymic emigrants are newly generated T cells that need to undergo postthymic maturation to gain functional competency and enter the long-lived naive T cell pool. The mechanism of T cell maturation remains incompletely understood. Previously, we demonstrated that the transcriptional repressor NKAP is required for T cell maturation. Because NKAP associates with histone deacetylase 3 (HDAC3), we examined whether HDAC3 is also required for T cell maturation. Although thymic populations are similar in CD4-cre HDAC3 conditional knockout mice compared with wild-type mice, the peripheral numbers of CD4(+) and CD8(+) T cells are dramatically decreased. In the periphery, the majority of HDAC3-deficient naive T cells are recent thymic emigrants, indicating a block in T cell maturation. CD55 upregulation during T cell maturation is substantially decreased in HDAC3-deficient T cells. Consistent with a block in functional maturation, HDAC3-deficient peripheral T cells have a defect in TNF licensing after TCR/CD28 stimulation. CD4-cre HDAC3 conditional knockout mice do not have a defect in intrathymic migration, thymic egress, T cell survival, or homeostasis. In the periphery, similar to immature NKAP-deficient peripheral T cells, HDAC3-deficient peripheral T cells were bound by IgM and complement proteins, leading to the elimination of these cells. In addition, HDAC3-deficient T cells display decreases in the sialic acid modifications on the cell surface that recruit natural IgM to initiate the classical complement pathway. Therefore, HDAC3 is required for T cell maturation.
Flowerlike ZnO Nanostructures via Hexamethylenetetramine-Assisted Thermolysis of Zinc−Ethylenediamine Complex (2005)

Flowerlike ZnO nanostructures (FZNs) have been deposited on Si substrate from aqueous solution by the hexamethylenetetramine (HMT)-assisted thermolysis of zinc-ethylenediamine (en) complex at low temperature (95 degrees C) and in a short time (60 min). Obtained FZNs exhibit well-defined flowerlike morphology, hexagonal wurtzite structure, and strong UV photoluminescence. The flower petals constructed by many well-aligned nanorods possess the typical tapering feature with tip sizes of 30-50 nm. Effects of en, zinc-en molar ratio, HMT, and reaction time were investigated. Results show that en is determinative to the formation of FZNs, and the partial capping of NH(3).(CH(2))(2).NH(3) molecules on the side surface of the ZnO crystal is responsible for the tapering feature of petals. HMT can step into the nucleation process of ZnO and inhibit the formation of nanorods on the substrate by preventing heterogeneous precipitation. Moreover, the formation of twin crystal ZnO nuclei at low precursor concentrations and their further evolution into spindle crystals with clear middle interfaces are also vitally important for the development of FZNs.
A normal form solution to the singular inverse kinematic problem for robotic manipulators: the quadratic case (2002)

We present a normal form approach to solving the singular inverse kinematic problem for non-redundant robot kinematics. A standing assumption is made that singular configurations of the kinematics have corank 1 and that the kinematics are equivalent to the quadratic normal form. The approach has been illustrated with a simulation case study of 2R kinematics. A comparison with the singularity-robust inverse technique and the null-space based approach has demonstrated advantages of the normal form approach.
Contribution of QR-Codes to the Marketing Mix − A Case Study (2014)

The mobilisation of IT-applications over the past few years has opened up new opportunities for business companies to develop mobile marketing strategies. QR-Codes, as the most popular way of mobile tagging, enable a pull mobile marketing strategy, wherein customers can request information about products or services that interest them by scanning a code with their mobile devices. This study provides an assessment of the potential contribution of QR-Codes to marketing mix elements, using the familiar framework of the four Ps (product, price, promotion, place) and the four Cs (costumer, cost, communication, convenience). In order to investigate the influences of QR-Codes in the context of marketing mix elements, a case study about QR-Code based mobile marketing activities of B/S/H/ Turkey (one of the leading electronic home appliances companies in Turkey) is presented.
Flexor Tendon Injuries in the Hand: A UK Survey of Repair Techniques and Suture Materials—Are We Following the Evidence? (2014)

Introduction . Injuries to the hand are common, and poor functional outcomes can have significant long-term consequences affecting both work and social activities. Good outcomes following flexor tendon lacerations in the hand are dependent on a sound surgical repair allowing early active mobilisation. Materials and Methods . We reviewed the literature regarding the choice of suture material and repair technique. We then carried out a nationwide postal survey of plastic surgery hand units to assess the level of compliance with the evidence. Results . Fifty-four units were surveyed. The response rate was 72%, with the most popular core suture being Prolene (64%) and the most popular technique being the Kessler repair (36%). Discussion . Current evidence advocates a multistrand repair using Ethibond. We found that the majority of units are not following the evidence. We suggest the use of evidence-based departmental guidelines to improve the practice and outcomes following these common injuries.
Preparation of chiral substituted succinic acids (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation of chiral substituted succinic acidsJoginder S. Bajwa and Marvin J. MillerCite this: J. Org. Chem. 1983, 48, 7, 1114–1116Publication Date (Print):April 1, 1983Publication History Published online1 May 2002Published inissue 1 April 1983https://pubs.acs.org/doi/10.1021/jo00155a042https://doi.org/10.1021/jo00155a042research-articleACS PublicationsRequest reuse permissionsArticle Views427Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Standardised methodology of sputum induction and processing (2002)

Research into the pathogenetic mechanisms and clinical monitoring of inammatory diseases of any system is complete only if it involves the study of both the underlying pathological features and the physio- logical consequences that result from what are always complex inammatory processes. Respiratory dis- eases, including those of the airways, are no exception in this respect. It is, therefore, not surprising that the development over the last 25 years of techniques enabling the study of inammatory processes in the airways has revolutionised understanding of the commonest pulmonary diseases, asthma and chronic obstructive pulmonary disease (COPD). Airways inammation is now an established feature and a central consideration of any treatment strategy for both of these conditions. Most of the initial observations made in asthma, documenting the involvement of eosinophils, mast cells, T-cells and more recently structural cells, ® broblasts, endothelial cells and epithelial cells, were made in studies using ® breoptic bronchoscopy in
THE CLASSIFIED ADS (1996)

range from $355 to $675 based upon size.
p21/waf1/cip1 and mdm-2 expression in breast carcinoma patients as related to prognosis (1997)

p21/waf1/cip1 and mdm-2 are downstream effectors of p53. p21 plays a major role in negatively regulating cell-cycle progression, while mdm-2 inhibits p53 effects, and its role has been implicated in oncogenesis. In this study, we investigated the expression profiles of p21, mdm-2 and p53 in human breast-carcinoma tissues. The aim was to determine whether a correlation exists between the expression profiles of these markers and tumor differentiation, ER status and prognosis. We studied tumor specimens obtained from 106 patients and found a highly significant association among low histology grade, p53 over-expression, high mdm-2 expression and lack of p21 expression. Our studies also demonstrate that, in human breast cancer, low levels of p21 and higher mdm-2 levels directly correlate with the onset of lymph-node metastases and shortened patient survival. Furthermore, the expression profiles of p21, mdm-2 and p53 were independently correlated with patient survival.
An Overview of Artificial Gravity (1973)

The unique characteristics of artificial gravity that affect human performance and physiology in an artificial gravity environment are reviewed. The rate at which these unique characteristics change decreases very rapidly with increasing radius of a rotating vehicle used to produce artificial gravity. Reducing their influence on human performance or physiology by increasing radius becomes a situation of very rapidly diminishing returns. A review of several elements of human performance has developed criteria relative to the sundry characteristics of artificial gravity. A compilation of these criteria indicates that the maximum acceptable rate of rotation, leg heaviness while walking, and material handling are the factors that define the minimum acceptable radius. The ratio of Coriolis force to artificial weight may also be significant. Based on current knowledge and assumptions for the various criteria, a minimum radius between 15.2 and 16.8 m seems desirable.
Adequate connexin-mediated coupling is required for proper insulin production. (1995)

To assess whether connexin (Cx) expression contributes to insulin secretion, we have investigated normal and tumoral insulin-producing cells for connexins, gap junctions, and coupling. We have found that the glucose-sensitive cells of pancreatic islets and of a rat insulinoma are functionally coupled by gap junctions made of Cx43. In contrast, cells of several lines secreting insulin abnormally do not express Cx43, gap junctions, and coupling. After correction of these defects by stable transfection of Cx43 cDNA, cells expressing modest levels of Cx43 and coupling, as observed in native beta-cells, showed an expression of the insulin gene and an insulin content that were markedly elevated, compared with those observed in both wild-type (uncoupled) cells and in transfected cells overexpressing Cx43. These findings indicate that adequate levels of Cx-mediated coupling are required for proper insulin production and storage.
Change management in object-oriented databases (2002)

The author addresses two of the key issues of change management in advanced application databases that are reuse of objects in a changed environment and change propagation. Changes usually propagate along certain relationships between object in many advanced application databases. A database model is proposed called an active h-graph object model (AHOM), to address change management in object-oriented databases. AHOM is unique in its ability to represent every object in a database as a communicating agent in the object's dynamic environment, and consequently, changes are represented and controlled through the dynamic environments of the objects in the database. It is shown that AHOM may be used to manage changing objects in advanced application databases.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The Spruce System: Quality Verification of Linux File Systems Drivers (2012)

This paper is dedicated to the problem of dynamic verification of Linux file system drivers. Alongside with some existing solutions, the Spruce system is presented, which is dedicated to verification of drivers of certain Linux file systems. This system is being developed in the System Programming Laboratory of Russian-Armenian (Slavonic) University in Armenia. Spruce provides a large variety of tests for file system drivers. These tests help not only verify the file system functionality, but also watch the behavior of the driver in case of system failures and in rare paths.
Specificity of proteinase K from Tritirachium album limber for synthetic peptides. (1975)

The specificity of proteinase K from Tritirachium album Limber was determined using various synthetic peptide substrates. The esterase activity against N-acylated amino acid esters indicated that the enzyme is primarily specific against aromatic or hydrophobic amino acid residues at the carboxyl side of the splitting point. Secondary interaction for hydrolysis was also studied using peptide esters or others, which showed that the enzyme activity is markedly promoted by elongating the peptide chain to the N-terminal from the splitting point. Thus, peptide chloromethyl ketone derivatives such as Cbz-Ala-Gly-PheCH2Cl inactivated the enzyme activity markedly.
A simple and reliable class E inverter for induction heating applications (1998)

A simple and reliable class E inverter for induction heating applications is proposed. Its topology presents only one power electronic switch. Control strategy is based in switch current sensing. The circuit model behaviour is analysed, and the limits of normal operation and components aspects (construction, stresses etc.) are also discussed. Computer simulations are presented and compared with results measured on the operational prototype, in order to validate both the theoretical model and computer simulation.
Head injuries: a prospective, computerized study. (1985)

A prospective study of 3000 consecutive patients with head injury admitted to hospital showed a marked seasonal, daily and hourly variation and an overall male-to-female ratio of 2.19:1. The majority of patients were in the second, third and fourth decades of life with a peak in the early part of the second decade. The incidence was highest in unemployed and welfare recipients. Traffic accidents were the leading cause followed by fights and falls. Drug or alcohol use, or both, was evident in 45.6% of cases. The number of head injuries caused by intoxicated individuals is not known. Most patients had a concussion only. There was no evidence that the patients with concussion who returned to full activity immediately had any more adverse effects than those advised to "take it easy" for about 1 week.
Exposing digital forgeries from 3-D lighting environments (2010)

When creating a photographic composite, it can be difficult to match lighting conditions. We describe a technique for measuring lighting conditions in an image, and describe its use in detecting photographic composites. Specifically, we describe how to approximate a 3-D lighting environment with a low-dimensional model and how to estimate the model's parameters from a single image. Inconsistencies in the lighting model are then used as evidence of tampering.
New books - Fluorines chemistry reviews, vol. 3 (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew books - Fluorines chemistry reviews, vol. 3Paul TerrantCite this: Anal. Chem. 1969, 41, 14, 65APublication Date (Print):December 1, 1969Publication History Published online21 September 2008Published inissue 1 December 1969https://pubs.acs.org/doi/10.1021/ac50159a014https://doi.org/10.1021/ac50159a014research-articleACS PublicationsRequest reuse permissionsArticle Views18Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Factors related to infant apnoea and cyanosis: A population‐based study (1997)

Several infant and parental characteristics are associated with increased risk of infant apnoea/cyanosis in this study but further population-based work with a larger group of infants hospitalised for apnoea/cyanosis should be conducted. The finding of an association between the administration of antihistamine medication and infant cyanosis highlights the possibility of adverse side-effects if antihistamine medication is administered to young infants.
Next-generation sequencing technologies and applications for human genetic history and forensics (2011)

Rapid advances in the development of sequencing technologies in recent years have enabled an increasing number of applications in biology and medicine. Here, we review key technical aspects of the preparation of DNA templates for sequencing, the biochemical reaction principles and assay formats underlying next-generation sequencing systems, methods for imaging and base calling, quality control, and bioinformatic approaches for sequence alignment, variant calling and assembly. We also discuss some of the most important advances that the new sequencing technologies have brought to the fields of human population genetics, human genetic history and forensic genetics.
Virtual Testing with Validated Analysis Tools (2003)

Collier Research Corporation is working with Lockheed Martin Aeronautics (LM Aero) under United States Air Force Research Lab (AFRL) funding to develop a "certification-by-analysis" process to reduce unexpected failures during experimental testing that will, in turn, accelerate Air Force structural certification. The goal is early identification and avoidance of conceptual and preliminary design problems on new and sustaining aircraft programs using a "design-by-analysis" process that includes the commercial structural sizing software called HyperSizer.
Low serum amylase in association with metabolic syndrome and diabetes: A community-based study (2011)

Our results indicate that low serum amylase is associated with increased risk of metabolic abnormalities, MetS and diabetes. These results suggest a pancreatic exocrine-endocrine relationship in certain clinical conditions.
AFGL atmospheric constituent profiles (0-120km) (1986)

An atmospheric data base consisting of volume mixing ratios (o0 to 12okm) for twenty eight (28) minor and trace gases has been assembled for use with spectral radiance transmittance models. Six references atmospheres, each defining temperature, pressure and density as a function of altitude (selected from the U.S. Standard Supplements, 1966 and the U.S. Standard Atmosphere, 1976) provide a range of climatological choices. Analogous zonal-mean descriptions for 2O, O3, N2O, CO, and CH4 have been subsequently adapted from satellite data and/or dynamical-photochemical analyses. The remaining species are defined by single profiles, usually appropriate for U.S. Standard conditions. Because the entire profile set is preferentially based on available measurements, explicit photochemical consistency between the different species has not been maintained. Keywords: ATMOSPHERIC CONSTITUENTS; TEMPERATURE PROFILES; MODEL ATMOSPHERES.
PAAS 3: A computer program to determine probable sequence of peptides from mass spectrometric data (1984)

The computer program PAAS 3 is developed to determine the probable amino acid sequences of a peptide from sequence ion peaks experimentally obtained by mass spectrometry.
Phase-change materials for non-volatile memory devices: from technological challenges to materials science issues (2017)

Abstract Chalcogenide phase-change materials (PCMs), such as Ge-Sb-Te alloys, have shown outstanding properties, which has led to their successful use for a long time in optical memories (DVDs) and, recently, in non-volatile resistive memories. The latter, known as PCM memories or phase-change random access memories (PCRAMs), are the most promising candidates among emerging non-volatile memory (NVM) technologies to replace the current FLASH memories at CMOS technology nodes under 28 nm. Chalcogenide PCMs exhibit fast and reversible phase transformations between crystalline and amorphous states with very different transport and optical properties leading to a unique set of features for PCRAMs, such as fast programming, good cyclability, high scalability, multi-level storage capability, and good data retention. Nevertheless, PCM memory technology has to overcome several challenges to definitively invade the NVM market. In this review paper, we examine the main technological challenges that PCM memory technology must face and we illustrate how new memory architecture, innovative deposition methods, and PCM composition optimization can contribute to further improvements of this technology. In particular, we examine how to lower the programming currents and increase data retention. Scaling down PCM memories for large-scale integration means the incorporation of the PCM into more and more confined structures and raises materials science issues in order to understand interface and size effects on crystallization. Other materials science issues are related to the stability and ageing of the amorphous state of PCMs. The stability of the amorphous phase, which determines data retention in memory devices, can be increased by doping the PCM. Ageing of the amorphous phase leads to a large increase of the resistivity with time (resistance drift), which has up to now hindered the development of ultra-high multi-level storage devices. A review of the current understanding of all these issues is provided from a materials science point of view.