gebhart/patrepeval huggingface dataset:
Characterization of GaN epitaxial layer grown on nano-patterned Si(111) substrate using Pt metal-mask (2014)

본 연구에서는 Si(111) 기판을 이용하여 고품질의 GaN 박막을 성장하기 위하여 다양한 패턴을 갖는 Si 기판을 제작하였다. Si(111) 기판위에 이온 스퍼터(ion-sputter)를 이용하여 Pt 박막을 증착한 후 열처리(thermal annealing)하여 Pt 금속 마스크를 형성하고 유도 결합 플라즈마 이온 식각(inductively coupled plasma-reactive ion etching, ICP-RIE) 공정을 통하여 기둥(pillar)형태의 나노 패턴된 Si(111) 기판을 제작하였고 리소그래피 공정을 통하여 마이크로 패턴된 Si(111) 기판을 제작하였다. 일반적인 Si(111) 기판, 마이크로 패턴된 Si(111) 기판 및 나노 패턴된 Si(111) 기판위에 유기화학기상증착(metal organic chemical vapor deposition, MOCVD) 방법으로 GaN 박막을 성장하여 표면 특성과 결정성 및 광학적 특성을 분석하였다. 나노 패턴된 Si(111) 기판위에 성장한 GaN 박막은 일반적인Si(111) 기판과 마이크로 패턴된 Si(111) 기판위에 성장한 GaN 박막보다 표면의 균열과 거칠기가 개선되었다. 나노 패턴된 Si(111) 기판위에 성장한 GaN (002)면과 (102)면에 x-선 회절(x-ray diffraction, XRD) 피크의 반폭치(full width at half maximum, FWHM)는 576 arcsec, 828 arcsec으로 다른 두 기판위에 성장한 GaN 박막 보다 가장 낮은 값을 보여 결정성이 향상되었음을 확인하였다. Photoluminescence(PL)의 반폭치는 나노 패턴된 Si(111) 기판위에 성장한 GaN 박막이 46.5 meV으로 다른 기판위에 성장한 GaN 박막과 비교하여 광학적 특성이 향상되었음을 확인하였다. An attempt to grow high quality GaN on silicon substrate using metal organic chemical vapor deposition (MOCVD), herein GaN epitaxial layers were grown on various Si(111) substrates. Thin Platinum layer was deposited on Si(111) substrate using sputtering, followed by thermal annealing to form Pt nano-clusters which act as masking layer during dry-etched with inductively coupled plasma-reactive ion etching to generate nano-patterned Si(111) substrate. In addition, micro-patterned Si(111) substrate with circle shape was also fabricated by using conventional photo-lithography technique. GaN epitaxial layers were subsequently grown on micro-, nano-patterned and conventional Si (111) substrate under identical growth conditions for comparison. The GaN layer grown on nano-patterned Si (111) substrate shows the lowest crack density with mirror-like surface morphology. The FWHM values of XRD rocking curve measured from symmetry (002) and asymmetry (102) planes are 576 arcsec and 828 arcsec, respectively. To corroborate an enhancement of the growth quality, the FWHM value achieved from the photoluminescence spectra also shows the lowest value (46.5 meV) as compare to other grown samples.
Effects of laminin‐coated carbon nanotube/chitosan fibers on guided neurite growth (2011)

This study assesses the ability and potential of carbon nanotube (CNT)/chitosan to guide axon re-growth after nerve injuries. The CNT/chitosan fibers were produced via the coagulation and hydrodynamic focusing method. Fiber width and morphology were adjusted using such parameters as syringe pumping rate and the coagulant used. The CNT/chitosan fiber diameters were 50-300 μm for syringe pumping rates of 6-48 mL/h. Polyethylene glycol/NaOH (25%, w/w) solution was a suitable coagulant for forming fibers with small diameters. Physical property tests demonstrate that the CNT/chitosan composites had superior tensile strength and electrical conductivity compared with those of chitosan alone. The MTT and LDH tests reveal that CNT/chitosan composites were not cytotoxic. To improve the neural cell affinity of CNT/chitosan fibers, laminin was incorporated onto fiber surfaces via the oxygen plasma technique; cell adhesion ratio increased significantly from 3.5% to 72.2% with this surface modification. Immunofluorescence staining and SEM imaging indicate that PC12 cells adhered successfully and grew on the laminin (LN)-coated CNT/chitosan films and fibers. Experimental results show that PC12 grown on LN-coated CNT/chitosan fibers in vitro extend longitudinally oriented neurites in a manner similar to that of native peripheral nerves. With the inherent electrical properties of CNTs, oriented CNT/chitosan fibers have a potential for use as nerve conduits in nerve tissue engineering.
LOS: Local-Optimistic Scheduling of Periodic Model Training For Anomaly Detection on Sensor Data Streams in Meshed Edge Networks (2021)

Anomaly detection is increasingly important to handle the amount of sensor data in Edge and Fog environments, Smart Cities, as well as in Industry 4.0. To ensure good results, the utilized ML models need to be updated periodically to adapt to seasonal changes and concept drifts in the sensor data. Although the increasing resource availability at the edge can allow for in-situ execution of model training directly on the devices, it is still often offloaded to fog devices or the cloud. In this paper, we propose Local-Optimistic Scheduling (LOS), a method for executing periodic ML model training jobs in close proximity to the data sources, without overloading lightweight edge devices. Training jobs are offloaded to nearby neighbor nodes as necessary and the resource consumption is optimized to meet the training period while still ensuring enough resources for further training executions. This scheduling is accomplished in a decentralized, collaborative and opportunistic manner, without full knowledge of the infrastructure and workload. We evaluated our method in an edge computing testbed on real-world datasets. The experimental results show that LOS places the training executions close to the input sensor streams, decreases the deviation between training time and training period by up to 40% and increases the amount of successfully scheduled training jobs compared to an in-situ execution.
Epigenetic Regulation of c-ROS Receptor Tyrosine Kinase Expression in Malignant Gliomas (2009)

The proto-oncogene tyrosine kinase c-ROS is an orphan receptor whose normal expression pattern is tightly spatio-temporally restricted during development. In glioma, c-ROS mRNA expression is frequently ectopically up-regulated. In this study, we determined by immunohistochemical means that c-ROS receptor protein is present in 25% of low-grade and 30% of malignant glioma tumor samples from tissue microarrays. We then explored the molecular basis for the up-regulation of c-ROS expression in these tumors. We identified and characterized the c-ROS gene promoter region and report that the ectopic expression of c-ROS in tumors is tied to hypomethylation of a CpG island in the c-ROS promoter. Bisulfite sequencing analysis in glioma tumor samples revealed that demethylation of the CpG island (-384 to -132 bp) correlated with c-ROS expression. Moreover, c-ROS expression could be activated by treatment of c-ROS-negative cells with the demethylating agent 5-aza-2'-deoxycytidine. These results establish a strong link between c-ROS promoter demethylation and gain of c-ROS expression and function in glioma. Our data suggest that epigenetic activation of c-ROS represents an important oncogenic mechanism for glioma initiation and progression and suggest that cautionary measures in the clinical use of 5-aza-dC for the treatment of glioma be taken into consideration. [Cancer Res 2009;69(6):2180-4].
Interparticle Electron Transfer in Metal/Semiconductor Composites. Picosecond Dynamics of CdS-Capped Gold Nanoclusters (1997)

Composite nanoclusters of gold and CdS with core/shell geometry have been synthesized using a chemical precipitation method in aqueous media. These nanoclusters are photoactive and exhibit transient bleaching in the 400−600 nm region when subjected to 355 nm laser pulse excitation. Capping of gold colloids with ultrasmall CdS nanoclusters (particle diameter ∼4 nm) significantly alters the picosecond dynamics of the gold core. The bleaching of the surface plasmon absorption of the gold core is achieved by exciting the CdS shell. The major fraction of the interparticle electron transfer between CdS and Au nanoclusters is completed within the laser pulse duration of 18 ps.
Prognostic markers for colorectal cancer: Expression of P53 and BCL2 (1997)

P53 is a tumor suppressor gene that has been implicated in the pathogenesis of a wide range of tumor types including colorectal cancers. bcl2 is a proto-oncogene that inhibits apoptosis. Immunostaining for P53 and BLC2 protein product was performed in a retrospective series of 80 colorectal carcinomas with a minimum follow-up of 5 years. The aim of the study was to evaluate the prognostic significance of P53 and BCL2 protein expression and their correlation with clinicopathologic variables such as pathologic disease stage (Dukes system), histologic grade, and vascular invasion. The patients were 41 to 76 years of age, and the follow-up ranged between 5 and 10 years. Among the 80 cases, 30 were Dukes stage A and 50 stage B. We found vascular invasion in 21.2%. P53 and BCL2 expression was detected, respectively, in 30.0% and 8.8%. We concluded that the P53 and BCL2 expression detected by immunohistochemistry in routinely processed, paraffin-embedded tissues: (1) has no prognostic significance; and (2) was not correlated with pathologic disease stage, histologic grade, or vascular invasion. Nevertheless, the number of patients in our study was small, and we believe that investigation of a larger series of patients is indicated.
Context-aware Natural Language Generation for Spoken Dialogue Systems. (2016)

Natural language generation (NLG) is an important component of question answering(QA) systems which has a significant impact on system quality. Most tranditional QA systems based on templates or rules tend to generate rigid and stylised responses without the natural variation of human language. Furthermore, such methods need an amount of work to generate the templates or rules. To address this problem, we propose a Context-Aware LSTM model for NLG. The model is completely driven by data without manual designed templates or rules. In addition, the context information, including the question to be answered, semantic values to be addressed in the response, and the dialogue act type during interaction, are well approached in the neural network model, which enables the model to produce variant and informative responses. The quantitative evaluation and human evaluation show that CA-LSTM obtains state-of-the-art performance.
PRIMA: passive reduced-order interconnect macromodeling algorithm (1997)

This paper describes PRIMA, an algorithm for generating provably passive reduced order N-port models for RLC interconnect circuits. It is demonstrated that, in addition to requiring macromodel stability, macromodel passivity is needed to guarantee the overall circuit stability once the active and passive driver/load models are connected. PRIMA extends the block Arnoldi technique to include guaranteed passivity. Moreover, it is empirically observed that the accuracy is superior to existing block Arnoldi methods. While the same passivity extension is not possible for MPVL, we observed comparable accuracy in the frequency domain for all examples considered. Additionally a path tracing algorithm is used to calculate the reduced order macromodel with the utmost efficiency for generalized RLC interconnects.
Study on Fuel Consumption Improvement in SI Engine with EGR for Hybrid Electric Vehicle (2008)

EGR(exhaust gas recirculation) is considered as a most effective method to reduce the NOx emissions. But high EGR tolerance is always pursued not only for its advantages of the pumping loss reduction and fuel economy benefit in Gasoline-Hybrid engine. However, the occurrence of excessive cyclic variation with high EGR normally prevents substantial fuel economy improvements from being achieved in practice. Therefore, the optimum EGR rate should be carefully determined in order to achieve low fuel consumption and low exhaust emission. In this study, 2 liters gasoline engine with E-EGR system was used to investigate the effects of EGR on fuel efficiency, combustion stability, engine performance and exhaust emissions. With optimal EGR rates, the fuel consumption was improved by 4%. This improvement was achieved while a reduction in NOx emissions of 75% was accomplished. Increase of EGR gas temperature causes the charge air temperature to affect the knock phenomenon and moreover, the EGR valve lift changes for the same control signal.
Forensically-Sound Methods to Collect Live Network Evidence (2013)

In the last decade Digital Forensics has experienced several issues when dealing with network evidence. An analyst, which is in charge of managing evidence flowing over a network have to face problems due to the volatile nature of such information. In facts, such data may change over time, may be lying on a server out of the his jurisdiction, or geographically far from where the crime was committed. In this paper two methods to allow remote collection of network evidence produced by online services such as web pages, chats, documents, photos and videos are presented. They enable the analyst to drive the acquisition process through the online services considered potential sources of evidence. During the process, all data flowing through the network is automatically collected (i.e., all the IP packets). The second one also collects the graphical representation of the acquisition (e.g., how the browser visualizes such data). Both methods introduce a trusted third party (acting as a digital notary) which is in charge of collecting and ``certifying'' network evidence. Before closing the acquisition process, a detailed report of the collected evidence is generated and made available to the analyst along with the collected data. Cryptographic primitives are used to demonstrate ex post data integrity, how it has been acquired and the acquisition time. As a proof of concept two prototypes have been implemented. To enhance the Court confidence of the collected evidence, at the same time, the service could be run across multiple coordinated servers acquiring the same data from different point of the network.
N antennas and their applications in portable handsets (1997)

A new antenna, the N antenna, is proposed for use in mobile communication systems. Detailed investigations are presented through the results obtained using numerical simulations and measurements. The newly proposed antenna has many attractive features such as a wide bandwidth, stable radiation patterns, and a compact structure. The application of the N antenna is exemplified through portable handsets. It is shown that in the presence of an operator, the efficiency of the antenna system of a portable handset increases and the maximum specific absorption rate (SAR) is significantly reduced by using the N antenna.
Amplification of FRS2 and Activation of FGFR/FRS2 Signaling Pathway in High-Grade Liposarcoma (2013)

Fibroblast growth factor (FGF) receptor (FGFR) substrate 2 (FRS2) is an adaptor protein that plays a critical role in FGFR signaling. FRS2 is located on chromosome 12q13-15 that is frequently amplified in liposarcomas. The significance of FRS2 and FGFR signaling in high-grade liposarcomas is unknown. Herein, we first comparatively examined the amplification and expression of FRS2 with CDK4 and MDM2 in dedifferentiated liposarcoma (DDLS) and undifferentiated high-grade pleomorphic sarcoma (UHGPS). Amplification and expression of the three genes were identified in 90% to 100% (9-11 of 11) of DDLS, whereas that of FRS2, CDK4, and MDM2 were observed in 55% (41 of 75), 48% (36 of 75), and 44% (33/75) of clinically diagnosed UHGPS, suggesting that these "UHGPS" may represent DDLS despite lacking histologic evidence of lipoblasts. Immunohistochemical analysis of phosphorylated FRS2 protein indicated that the FGFR/FRS2 signaling axis was generally activated in about 75% of FRS2-positive high-grade liposarcomas. Moreover, we found that FRS2 and FGFRs proteins are highly expressed and functional in three high-grade liposarcoma cell lines: FU-DDLS-1, LiSa-2, and SW872. Importantly, the FGFR selective inhibitor NVP-BGJ-398 significantly inhibited the growth of FU-DDLS-1 and LiSa-2 cells with a concomitant suppression of FGFR signal transduction. Attenuation of FRS2 protein in FU-DDLS-1 and LiSa-2 cell lines decreased the phosphorylated extracellular signal-regulated kinase 1/2 and AKT and repressed cell proliferation. These findings indicate that analysis of FRS2 in combination with CDK4 and MDM2 will more accurately characterize pathologic features of high-grade liposarcomas. Activated FGFR/FRS2 signaling may play a functional role in the development of high-grade liposarcomas, therefore, serve as a potential therapeutic target.
Evaluation of balance during activities of daily living (2003)

The skill of balance is essential for activities of daily living. Through the use of a triaxial accelerometer and a portable data logger the skill of balance can be assessed during: quiet standing, walking, ascending steps, descending steps, sitting-down in a chair, and standing-up from a chair. Results are reported as performance parameters. Comparing the results obtained by the same control subject before and after a time comparable to that of a therapeutic intervention, paired Student t tests show consistency over time but significant changes under different test conditions in the same session.
The Outlook for Energy: A View to 2040 (2020)

technology, the development of new supply sources, political events, demographic changes, and other factors discussed herein and under the heading "Factors Affecting Future Results" in the Investors section of our website at: www.exxonmobil.com
Somatically mutated IgG anti‐DNA antibody clonally related to germ‐line encoded IgM anti‐DNA antibody (1992)

Among 15 anti-DNA antibody-producing hybridomas derived from a single NZB X NZW F1 mouse, an IgM and an IgG were shown to use the same VH gene of the Q52 family. Using a combination of two primers both consisting of a mixture of oligonucleotides (one complementary to the 5' end of VH segment and one to the 3' end of VH segment of Q52 family) we determined the sequences of several members of germ-line VH genes in the Q52 family derived from NZB and NZW strains. Comparison of the sequences with those of cloned VH cDNA obtained from the hybridomas revealed that the VH sequence of the IgM anti-DNA antibody was identical to that of a cloned NZW germ-line VH gene, except for the priming sites. In contrast, the VH sequence of the IgG counterpart contained somatically mutated nucleotides. Because the IgG anti-DNA antibody showed a higher DNA binding activity than did the IgM antibody, we conclude that these changes in nucleotide sequences were induced and selected through an antigen-driven mechanism as is the case in a normal immune response. It is tempting to speculate that the germ-line encoded, low-affinity IgM autoantibody undergoes somatic mutations and isotype switching, resulting in generation of pathogenic, high-affinity autoantibodies in autoimmune diseases.
Performance of a broadcast packet switch (1989)

The results of a simulation study undertaken to evaluate a high-performance packet-switching fabric supporting point-to-point and multipoint communications are presented. This switching fabric contains several components, each based on conventional binary routing networks. The most novel element is the copy network, which performs the packet replication needed for multipoint connections. Results characterizing the performance of the copy network are presented. Several architectural alternatives for conventional binary routing networks are also evaluated. For example, the performance gains obtainable by using cut-through switching in the context of binary routing networks with small buffers are quantified. One surprising result is that networks constructed from nodes with more then two input and output ports can perform less well than those constructed from binary nodes. This result is quantified and explained.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Robust Hydrophobic and Hydrophilic Polymer Fibers Sensitized by Inorganic and Hybrid Lead Halide Perovskite Nanocrystal Emitters (2019)

Advances in the technology and processing of flexible optical materials have paved the way toward the integration of semiconductor emitters and polymers into functional light emitting fabrics. Lead halide perovskite nanocrystals appear as highly suitable optical sensitizers for such polymer fiber emitters due to their ease of fabrication, versatile solution-processing and highly efficient, tunable, and narrow emission across the visible spectrum. A beneficial byproduct of the nanocrystal incorporation into the polymer matrix is that it provides a facile and low-cost method to chemically and structurally stabilize the perovskite nanocrystals under ambient conditions. Herein, we demonstrate two types of robust fiber composites based on electrospun hydrophobic poly(methyl methacrylate) (PMMA) or hydrophilic polyvinylpyrrolidone (PVP) fibrous membranes sensitized by green-emitting all-inorganic CsPbBr<sub>3</sub> or hybrid organic-inorganic FAPbBr<sub>3</sub> nanocrystals. We perform a systematic investigation on the influence of the nanocrystal-polymer relative content on the structural and optical properties of the fiber nanocomposites and we find that within a wide content range, the nanocrystals retain their narrow and high quantum yield emission upon incorporation into the polymer fibers. Quenching of the radiative recombination at the higher/lower bound of the nanocrystal:polymer mass ratio probed is discussed in terms of nanocrystal clustering/ligand desorption due to dilution effects, respectively. The nanocomposite's optical stability over an extended exposure in air and upon immersion in water is also discussed. The studies confirm the demonstration of robust and bright polymer-fiber emitters with promising applications in backlighting for LCD displays and textile-based light emitting devices.
Special Conference on Tumor Immunology and Immunotherapy: A New Chapter (2015)

The overall objective of the fifth American Association for Cancer Research Special Conference, "Tumor Immunology and Immunotherapy: A New Chapter," organized by the Cancer Immunology Working Group, was to highlight multidisciplinary approaches of immunotherapy and mechanisms related to the ability of immunotherapy to fight established tumors. With the FDA approval of sipuleucel-T, ipilimumab (anti-CTLA-4; Bristol-Myers Squibb), and the two anti-PD-1 antibodies, pembrolizumab (formerly MK-3475 or lambrolizumab; Merck) and nivolumab (Bristol-Myers Squibb), immunotherapy has become a mainstream treatment option for some cancers. Many of the data presented at the conference and reviewed in this article showcase the progress made in determining the mechanistic reasons for the success of some treatments and the mechanisms associated with tolerance within the tumor microenvironment, both of which are potential targets for immunotherapy. In addition to combination and multimodal therapies, improvements in existing therapies will be needed to overcome the numerous ways that tumor-specific tolerance thwarts the immune system. This conference built upon the success of the 2012 conference and focused on seven progressing and/or emerging areas-new combination therapies, combination therapies and vaccine improvement, mechanisms of antibody therapy, factors in the tumor microenvironment affecting the immune response, the microbiomes effect on cancer and immunotherapy, metabolism in immunotherapy, and adoptive T-cell therapy. Cancer Immunol Res; 3(6); 1-8. ©2015 AACR.
The monosaccharide transporter(‐like) gene family in <i>Arabidopsis</i> (2007)

The availability of complete plant genomes has greatly influenced the identification and analysis of phylogenetically related gene clusters. In Arabidopsis, this has revealed the existence of a monosaccharide transporter(-like) gene family with 53 members, which play a role in long-distance sugar partitioning or sub-cellular sugar distribution and catalyze the transport of hexoses, but also polyols and in one case also pentoses and tetroses. An update on the currently available information on these Arabidopsis monosaccharide transporters, on their sub-cellular localization and physiological function will be given.