gebhart/patrepeval huggingface dataset:
New Digital Control Architecture Eliminating the Need for High Resolution DPWM (2007)

Due to the non-linear quantization effects of A/D converter and digital pulse-width modulator (DPWM), limit cycle oscillation is hard to predict in the voltage-mode digital controlled switching power supplies. As a result, one dedicated DPWM with very high resolution is indispensable to reduce the limit cycle oscillations, which usually results complexity and high cost for digital controllers. This paper investigates a new digital control architecture eliminating the needs for high resolution DPWM, so that greatly cost reduction can be achieved. Experimental verification is done at the hardware prototype to verify the control concept.
Multiport Sensor RFIDs for Wireless Passive Sensing of Objects—Basic Theory and Early Results (2008)

A new family of passive sensor radio-frequency identification devices is here proposed for applications in the context of wireless sensor networks. The new tags, working in the ultra-high frequency band, are able to detect the value or the change of some features of the tagged body without using any specific sensor. Such tags are provided with multiple chips embedded either within a cluster of cooperating antennas or in a single multiport antenna, and exploit the natural mismatch of the antenna input impedance caused by the change of the tagged object. A basic theory of multiport sensor tags is formulated with the purpose to describe the possible classification and detection performances in a unitary context. Some numerical examples and a first experiment corroborate the feasibility of the idea.
Audiovisual Voice Activity Detection Based on Microphone Arrays and Color Information (2013)

Audiovisual voice activity detection is a necessary stage in several problems, such as advanced teleconferencing, speech recognition, and human-computer interaction. Lip motion and audio analysis provide a large amount of information that can be integrated to produce more robust audiovisual voice activity detection (VAD) schemes, as we discuss in this paper. Lip motion is very useful for detecting the active speaker, and in this paper we introduce a new approach for lips and visual VAD. First, the algorithm performs skin segmentation to reduce the search area for lip extraction, and the most likely lip and non-lip regions are detected using a Bayesian approach within the delimited area. Lip motion is then detected using Hidden Markov Models (HMMs) that estimate the likely occurrence of active speech within a temporal window. Audio information is captured by an array of microphones, and the sound-based VAD is related to finding spatio-temporally coherent sound sources through another set of HMMs. To increase the robustness of the proposed system, a late fusion approach is employed to combine the result of each modality (audio and video). Our experimental results indicate that the proposed audiovisual approach presents better results when compared to existing VAD algorithms.
Functional Vitamin B12 Deficiency and Determination of Holotranscobalamin in Populations at Risk (2003)

Our data support the concept that the measurement of holoTC and MMA provides a better index of cobalamin status than the measurement of total vitamin B12. HoloTC is the most sensitive marker, followed by MMA. The use of holoTC and MMA enables us to differentiate between storage depletion and functional vitamin B12 deficiency. Renal patients have a higher requirement of circulating holoTC. In renal dysfunction, holoTC cannot be used as a marker of vitamin B12 status.
Vitamin E Increases the Growth Inhibitory and Differentiating Effects of Tumor Therapeutic Agents on Neuroblastoma and Glioma Cells in Culture (1980)

The effects of vitamin E in combination with several pharmacological agents on neuroblastoma (NBP2) and glioma (C-6) cells in culture for the criteria of growth inhibition (due to cell death and reduction of cell division) and morphological changes were studied. Vitamin E in combination with 5-FU, adriamycin, R020-1724, vincristine, sodium butyrate, chlorozotocin, or PGE1 produced a synergistic effect on growth inhibition of NB cells, whereas, vitamin E in combination with bleomycin, CCNU, DTIC, mutamycin, or cis-platinum produced an additive effect for the same criterion. In glioma cell culture, vitamin E in combination with vincristine, R020-1724, and CCNU produced a synergistic effect on growth inhibition; whereas, vitamin E in combination with bleomycin, 5-FU, adriamycin, DTIC, papaverine, mutamycin, and cis-platinum produced an additive effect for the same criterion. Vitamin E failed to enhance the effect of sodium butyrate, PGE1, chlorozotocin on glioma cells. Bleomycin, CCNU, chlorozotocin, or vitamin E at concentrations used in this study did not increase the morphological differentiation of NB cells, however, vitamin E in combination with one of these agents markedly enhanced the number of morphologically differentiated NB cells. Adriamycin, PGE1, R020-1724, papaverine, mutamycin, and cis-platinum increased the expression of morphological differentiation of NB cells, but vitamin E enhanced the effect of these agents for this criterion. The treatment of glioma cells with vitamin E and pharmacological agents did not cause any significant change in morphological differentiation. These data also suggest that vitamin E may modulate the effects of pharmacological agents.
Cancer‐specific promoters for expression‐targeted gene therapy: <i>ran</i>, <i>brms1</i> and <i>mcm5</i> (2016)

The ran, brms1, and mcm5 promoters have the specificity and strength needed for cancer-specific expression-targeted gene therapy. (p) ran in particular produced exciting results when coupled with a version of the caspase 3 exon to treat bladder cancer. Copyright © 2016 John Wiley & Sons, Ltd.
Apparatus for measuring elastic constants of single crystals by a resonance technique up to 1825 K (1988)

By holding the rectangular parallelepiped specimen between long, thin alumina buffer rods, we can detect the resonance vibration of a specimen even at temperatures above 1800 K. This new technique, in combination with the theory for the calculation of the resonance frequency spectrum of a rectangular parallelepiped specimen, enables us to determine the high-temperature elastic properties of single-crystal materials. The first application of this new device was to determine the elastic stiffness constants of single-crystal corundum up to 1825 K.
Dizziness and Unstable Gait in Old Age (2015)

If a specific cause can be identified, dizziness and gait unsteadiness in old age can often be successfully treated. The common causes can be revealed by systematic clinical examination. Controlled clinical trials on the efficacy of treatments for elderly persons are urgently needed.
THE ACTION OF SULPHURIC ACID ON CERTAIN DERIVATIVES OF CYCLOPROPANE (1933)

A considerable variety of ketocyclopropanes has been submitted to the action of sulphuric acid, alone or in acetic acid. In general, the mode of reaction was similar to, though less drastic than, that of hydrogen bromide; this indicated a similar mechanism. When the cyclopropane ring was attacked, the product isolated was apparently formed by the addition of a molecule of water or acetic acid, or was the result of a secondary reaction dependent on a primary product so formed. The nitriles were hydrolyzed to amides without opening of the ring. A mechanism is suggested to account for the ring scission of cyclopropyl alcohols, which takes place in a different manner from most cyclopropane derivatives.
Inactivation of mismatch repair overcomes the barrier to transduction between Salmonella typhimurium and Salmonella typhi (1994)

P22 transduction of chromosomal genes from Salmonella typhimurium into Salmonella typhi occurs at a low frequency. Transduction of plasmids from S. typhimurium into S. typhi occurs at a frequency similar to that between S. typhimurium strains, indicating that the barrier to transduction of chromosomal genes is not due to an inability of P22 to inject DNA into S. typhi or a restriction endonuclease that rapidly degrades foreign DNA. Furthermore, transduction of mutS and mutL derivatives of S. typhi with chromosomal genes from S. typhimurium occurs efficiently. These results indicate that the transduction barrier is due to activity of the recipient mismatch repair system, which senses sequence divergence and disrupts heteroduplexes in favor of recipient sequences. Inactivation of the mismatch repair system allows P22 transduction to be used as an effective tool for constructing S. typhi-S. typhimurium hybrids.
An Improved Radioimmunoassay for Guanosine-5′-diphosphate-3′ diphosphate (ppGpp) and Its Application to Search for ppGpp in Rat Embryo and Brain (1981)

Journal Article An Improved Radioimmunoassay for Guanosine-5′-diphosphate-3′ diphosphate (ppGpp) and Its Application to Search for ppGpp in Rat Embryo and Brain Get access Yasutaro Hamagishi, Yasutaro Hamagishi Central Research Laboratories, Sanraku-Ocean Co., Ltd., Johnan, Fujisawa, Kanagawa 251, Japan Search for other works by this author on: Oxford Academic Google Scholar Toshio Kiyosaki, Toshio Kiyosaki Central Research Laboratories, Sanraku-Ocean Co., Ltd., Johnan, Fujisawa, Kanagawa 251, Japan Search for other works by this author on: Oxford Academic Google Scholar Toshikazu Oki, Toshikazu Oki Central Research Laboratories, Sanraku-Ocean Co., Ltd., Johnan, Fujisawa, Kanagawa 251, Japan Search for other works by this author on: Oxford Academic Google Scholar Hiroshi Tone, Hiroshi Tone Central Research Laboratories, Sanraku-Ocean Co., Ltd., Johnan, Fujisawa, Kanagawa 251, Japan Search for other works by this author on: Oxford Academic Google Scholar Tomoyuki Ishdcura Tomoyuki Ishdcura Central Research Laboratories, Sanraku-Ocean Co., Ltd., Johnan, Fujisawa, Kanagawa 251, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 45, Issue 12, 1 December 1981, Pages 2927–2929, https://doi.org/10.1080/00021369.1981.10864990 Published: 01 December 1981 Article history Received: 12 June 1981 Published: 01 December 1981
Role of Metal Contacts in High-Performance Phototransistors Based on WSe<sub>2</sub> Monolayers (2014)

Phototransistors based on monolayer transition metal dichalcogenides (TMD) have high photosensitivity due to their direct band gap transition. However, there is a lack of understanding of the effect of metal contacts on the performance of atomically thin TMD phototransistors. Here, we fabricate phototransistors based on large-area chemical vapor deposition (CVD) tungsten diselenide (WSe2) monolayers contacted with the metals of different work function values. We found that the low Schottky-contact WSe2 phototransistors exhibit a very high photo gain (10(5)) and specific detectivity (10(14)Jones), values higher than commercial Si- and InGaAs-based photodetectors; however, the response speed is longer than 5 s in ambient air. In contrast, the high Schottky-contact phototransistors display a fast response time shorter than 23 ms, but the photo gain and specific detectivity decrease by several orders of magnitude. Moreover, the fast response speed of the high Schottky-contact devices is maintained for a few months in ambient air. This study demonstrates that the contact plays an important role in TMD phototransistors, and barrier height tuning is critical for optimizing the photoresponse and photoresponsivity.
On the static performance of the RESURF LDMOSFETS for power ICs (2009)

This paper introduces a technology-specific relation for the static performance of high voltage lateral diffused MOSFETs. A similar relation, only dependent on material properties, is available for vertical power devices. Here we show that the static performance of the lateral power devices is influenced by the REduced SURface Field effect. Hence a technology-specific relation between the breakdown voltage and the specific on-resistance is proposed. The relation is not only material dependent but also involves two technology-dependent parameters. The proposed technology-specific static relation is substantiated by 2D numerical simulations, 1D analytical models and experimental results taken from the literature.
Cytotoxic Alkylated Hydroquinone, Phenol, and Cyclohexenone Derivatives from <i>Aspergillus violaceofuscus</i> Gasperini (2014)

New alkylated hydroquinones violaceoid A (1), violaceoid B (2), and violaceoid C (3), an alkylated phenol violaceoid D (4), and a cyclohexenoid violaceoid E (5) were isolated from a culture broth of Aspergillus violaceofuscus Gasperini isolated from moss. The structures were identified by interpretation of spectroscopic data (1D and 2D NMR, MS, and IR). Two known compounds, the cyclohexenoid 6 and eupenoxide (7), were also isolated. Compound 6 was isolated for the first time as a natural product and named violaceoid F. Isolated compounds were tested for cytotoxic activity against five human cancer cell lines and a mouse macrophage cell line. Violaceoid A was the most potent of the seven compounds against all cell lines. Violaceoid C and D exhibited cytotoxicity against the leukemia cell lines with LD50 values 5.9-8.3 μM, while violaceoid F was found to be cytotoxic against HCT116 and RAW264.7 with LD50 values of 6.4 and 6.5 μM, respectively. These results demonstrate that violaceoid derivatives are a new class of cytotoxic hydroquinones with a hydroxymethyl and a linear alkyl substituent.
New photodetector with cascaded waveguide photodiodes and resonant electrode structures for millimeter-wave subcarrier optical fiber link system (1999)

This paper presents a new photodetector operating at millimeter-wave range. The waveguide photodetector structure and a brief principle of the electrode design are described in this paper. By taking the advantages of narrow band operation in millimeter-wave subcarrier optic fiber link system, the proposed photodetector is designed to have cascaded resonant structures and a reflector to achieve high RF output. Resonators and reflector are realized by using one-fourth wavelength shorted stubs and an open stubs of coplanar waveguide, respectively. Velocity matching between optical waves and detected millimeter wave signals are performed by introducing an S-shaped meandering transmission line for the photocurrents.
Estimating the Wrong Graphical Model: Benefits in the Computation-Limited Setting (2006)

Consider the problem of joint parameter estimation and prediction in a Markov random field: that is, the model parameters are estimated on the basis of an initial set of data, and then the fitted model is used to perform prediction (e.g., smoothing, denoising, interpolation) on a new noisy observation. Working under the restriction of limited computation, we analyze a joint method in which the same convex variational relaxation is used to construct an M-estimator for fitting parameters, and to perform approximate marginalization for the prediction step. The key result of this paper is that in the computation-limited setting, using an inconsistent parameter estimator (i.e., an estimator that returns the wrong model even in the infinite data limit) is provably beneficial, since the resulting errors can partially compensate for errors made by using an approximate prediction technique. En route to this result, we analyze the asymptotic properties of M-estimators based on convex variational relaxations, and establish a Lipschitz stability property that holds for a broad class of convex variational methods. This stability result provides additional incentive, apart from the obvious benefit of unique global optima, for using message-passing methods based on convex variational relaxations. We show that joint estimation/prediction based on the reweighted sum-product algorithm substantially outperforms a commonly used heuristic based on ordinary sum-product.
The Kinetics of the α-Chymotrypsin-Catalyzed Hydrolysis of p-Nitrophenyl Acetate<sup>*</sup> (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Kinetics of the α-Chymotrypsin-Catalyzed Hydrolysis of p-Nitrophenyl Acetate*Ferenc J. Kezdy and Myron L. BenderCite this: Biochemistry 1962, 1, 6, 1097–1106Publication Date (Print):November 1, 1962Publication History Published online1 May 2002Published inissue 1 November 1962https://pubs.acs.org/doi/10.1021/bi00912a021https://doi.org/10.1021/bi00912a021research-articleACS PublicationsRequest reuse permissionsArticle Views3115Altmetric-Citations181LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A design method for skew tolerant latch design (2008)

This paper describes a new design method for skew-tolerant latch design (STLD) and evaluation on a commercial chip design. The conventional edge-triggered flip-flop (FF) design methods using clock synchronization are very practical, since only the timing constraints defined by a given clock frequency are optimized. However, clock skew that has a strong influence on clock frequency design prevents the FF design because of the variations. Thus, level-triggered latch design methods have been proposed as alternatives to FF-based design methods. An STLD is a kind of level-triggered latch design in which an FF is replaced by a pair of latches: a low-level triggered latch and a high-level triggered latch, and these two latches are moved after replacement. Although STLD can improve clock skew problems, this method is very complicated. We propose a new and more general design method for STLD that uses a new latch moving method. The experimental results indicated that about 6000 timing violation points were improved by using the proposed method on a 100KGate circuit without resulting in a large penalty area.
Affinity purification of proteins using ligands derived from peptide libraries (1995)

Peptide libraries can be used to identify ligands that bind specifically to a desired protein. These peptides may have significant advantages as specific ligands for affinity chromatography separations. This article describes the use of one of such peptide, Try-Asn-Phe-Glu-Val-Leu, as a ligand for the purification of S-protein using affinity chromatography. General strategies for peptide immobilization are discussed and the conditions for peptide immobilization to Emphazetrade mark gel are optimized. The effects of peptide orientation and peptide densities on protein binding are studied. Results indicate that the peptide affinity is not affected by the orientation of the peptide during immobilization, but association constants can be reduced by one order of magnitude when compared with the values in solution.With increased peptide density, the protein binding capacity of the gel increases, but both the percentage of peptide utilization and apparent binding constant between immobilized peptide and S-protein decrease. S-protein is separated from a mixture with BSA via affinity chromatography using specific elution with the peptide in solution.Finally, direct purification of S-protein from an enzymatic digestion mixture of ribonuclease A is demonstrated.(c) 1995 John Wiley & Sons, Inc.
The Experimental Production of Sarcoma by the Use of Beryllium Oxide. (1964)

Osteogenic sarcoma was produced experimentally by the repeated injection of beryllium oxide (BeO) directly into the right femur of rabbits. Young rabbits weighing 1.5 kg on the average were injected with 1 cc of 1.0 % suspension of beryllium oxide in physiologic saline solution. Ten rabbits were treated with a single injection of beryllium. Forty-three rabbits were twice a week for a total of divided into five groups. Of 30 rabbits which survived for more than 9 months Twenty-five rabbits (84%) developed osteogenic sarcoma, chondrosarcoma or presarcomatous changes.
Reviews (1991)

Abstract Mapping the modern Nicole Ward Jouve, White Woman Speaks with Forked Tongue: Criticism as Autobiography, Routledge, £35 hbk, £9.99 pbk. Christine Brooke‐Rose, Stories, Theories and Things, Cambridge University Press, £30 hbk. Rachel Blau DuPlessis, The Pink Guitar, Routledge, £35 hbk, £9.99 pbk. Janet Wolff, Feminine Sentences, Polity Press, £29.50 hbk, £9.95 pbk. 'Cats do not go to heaven' Elspeth Graham, Hilary Hinds, Elaine Hobby, Helen Wilcox (eds.), Her Own Life: Autobiographical Writings by Seventeenth‐Century Englishwomen Routledge £9.99. Caroline Lucas, Writing for Women: the Example of Woman as Reader in Elizabethan Romance, Open University Press, £10.99. Kirby Farrell, Elizabeth H. Hageman, Arthur F. Kinney (eds.), Women in the Renaissance: Selections from 'English Literary Renaissance', University of Massachussetts Press, £13.50. Mary Ann Schofield and Cecilia Macheski, Curtain Calls: British and American Women and the Theatre, 1660–1820, Ohio University Press, £37.95. Beyond representation ? the hysteric's Jouissance Monique David‐Ménard, Hysteria from Freud to Lacan. Body and Language in Psychoanalysis, trans. Catherine Porter, Cornell University Press. First published as L'Hysterique entre Freud et Lacan: Corps et langage enpsychanalyse, Editions Universitaires, 1983. A political lifestory Carolyn Steedman, Childhood, Culture and Class in Britain: Margaret McMillan 1860–1931, Virago, £16.99
Purification of Prorennin and Production of Its Antibody (1981)

Prorennin, i.e. the zymogen of rennin, was extracted from fresh calf stomach and purified by ammonium sulfate precipitation, ion exchange chromatography and gel filtration. The purified prorennin was homogeneous as judged by SDS-polyacrylamide gel electrophoresis. A specific antibody to the purified prorennin was induced in rabbits. In a double diffusion test and on immunoelectrophoresis the antibody gave a single precipitin line when run against crude and pure zymogen preparations. In the double diffusion test, the antibody also reacted with a purified rennin but not with gastric proteases (pepsin and pepsinogen) or other proteases (trypsin and Mucor rennin). When the antibody was tested against prorennin and rennin in the double diffusion test, a spur was formed at the junction of the precipitin lines against prorennin and rennin. This result confirms that the two proteins share an antigenically common structure in their molecules and that the activation segment of prorennin contains at least one antigenic determinant.