gebhart/patrepeval huggingface dataset:
Hybrid antibody mediated veto of cytotoxic T lymphocyte responses. (1996)

Strategies are being sought that allow the induction of specific tolerance to allogeneic transplants without affecting other immune functions. The so-called veto effect has been described as one such technology where CD8+ cells suppress responses of class I MHC-restricted T-lymphocyte precursors to antigens expressed by those CD8+ veto cells. Yet, veto inhibition will not be able to provide complete tolerance to allogeneic grafts since it only operates on cell populations that express CD8. Other types of cells prevalent in most organs express different tissue-specific antigens that are recognized by alloreactive T-cells. Therefore, complete tolerance to an allogeneic transplant can only be achieved if all cellular components within the graft acquire the immune-inhibitory function. Here, we studied whether the veto effect could be exploited for this purpose nevertheless. We produced a hybrid antibody (HAb) combining a mAb specific for a class I MHC molecule with a soluble CD8 molecule. We found that this HAb specifically and effectively transferred veto inhibition to different stimulator cell populations. Thus, we have developed a strategy that promises to selectively and completely tolerize graft-specific CTLs without affecting normal immune responses.
N-step incremental straight-line algorithms (1994)

This class of algorithms extends Bresenham's (1965) integer straight-line algorithm to generate more than one pixel per inner loop, thus reducing inner loop overhead. The quad-step algorithm is too large to justify its use in older hardware with limited memory space, but it can be viable in the context of modern memory and software sizes. Because the algorithm reduces both calculation overhead and the number of memory accesses for adjacent pixels, it can improve the performance of current systems that are limited in their processor speed and of future systems that might be limited in their memory speed. The algorithm gives results identical to those from Bresenham's single-step routine while drawing pixels in the expected direction from start to end point. Furthermore, as the gradual trend towards more bits per pixel continues, a processor supporting multi-word burst data instructions could make good use of this algorithm in speeding up line drawing into a 24-bits-per-pixel, 1-pixel-per-word color frame buffer. I chose to implement 4 steps per loop because it gave a useful performance improvement without exceeding the resources of the target processor, and it was small enough to hand-code. However, the techniques described can be used to construct a straight-line algorithm that generates more than 4 steps per loop. The relatively small average decision tree sizes indicate that algorithms of greater than 4 pixels per step might further improve line-drawing efficiency.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Can technical oscillators outperform the buy and hold strategy? (2015)

This study compares returns from the traditional buy and hold (B&H) strategy to well-known technical oscillators applied to diverse indices leading the global market (DJI, FTSE, NK225 and TA100) during the period 2007-2012. Our aim was to establish whether technical tools can consistently achieve returns exceeding those of the B&H strategy across various financial markets. We found the relative strength index (RSI) to be the best oscillator, outperforming the DJIA, the FTSE100 and the NK225 for five of the six years examined. The only index that did better than the RSI was TA100, which outperformed all the examined oscillators. In second place was the moving average convergence/divergence (MACD) oscillator, which outperformed the NK225 B&H strategy and came in second for TA100. The results show that during bear markets the RSI and MACD generally produce better gains than the indices, while the opposite occurs during bull markets.
Raman scattering of adsorbed molecules (1981)

The excitation energy dependence of the surface enhanced Raman scattering of adsorbed molecules is calculated based on the effective resonance model for a molecule–metal system. As a consequence of the effective resonant Raman process of the adsorbed molecule, a remarkable departure from an ω4 law is obtained near the excitation energies which satisfy the resonant condition. The significance of the substrate metal on the degree of the enhancement is discussed with the use of a result that the position of the effective resonant level is closely connected with that of the Fermi level. A comparison with the recent experimental results on the excitation profiles is also made.
Simultaneous deactivation and coating of porous silica particles for microcolumn supercritical fluid chromatography (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSimultaneous deactivation and coating of porous silica particles for microcolumn supercritical fluid chromatographyKent M. Payne, Bryon J. Tarbet, Jerald S. Bradshaw, Karin E. Markides, and Milton L. LeeCite this: Anal. Chem. 1990, 62, 14, 1379–1384Publication Date (Print):July 15, 1990Publication History Published online1 May 2002Published inissue 15 July 1990https://pubs.acs.org/doi/10.1021/ac00213a006https://doi.org/10.1021/ac00213a006research-articleACS PublicationsRequest reuse permissionsArticle Views139Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Feature-level fusion in multimodal biometrics (2004)

Multimodal biometric systems utilize the evidence presented by multiple biometric modalities (e.g., face and fingerprint, multiple fingers of a user, multiple impressions of a single finger, etc.) in order to determine or verify the identity of an individual. Information from multiple sources can be consolidated in three distinct levels [1]: (i) feature set level; (ii) match score level; and (iii) decision level. While fusion at the match score and decision levels have been extensively studied in the literature, fusion at the feature level is a relatively understudied problem. A novel technique to perform fusion at the feature level by considering two biometric modalities---face and hand geometry, is presented in this paper. Also, a new distance metric conscripted as the Thresholded Absolute Distance (TAD) is used to help reinforce the system's robustness towards noise. Finally, two techniques are proposed to consolidate information available after match score fusion, with that obtained after feature set fusion. These techniques further enhance the performance of the multimodal biometric system and help find an approximate upper bound on its performance. Results indicate that the proposed techniques can lead to substantial improvement in multimodal matching abilities.
Effect of intravenous alpha-difluoromethylornithine on the polyamine levels of normal tissue and a transplantable fibrosarcoma. (1987)

The effect of a continuous i.v. infusion of alpha-difluoromethylornithine (DFMO) on the polyamine metabolism of tumor and normal host tissue was determined. Non-tumor-bearing Fischer 344 rats or rats bearing a transplantable fibrosarcoma received continuous infusions of DFMO through a central venous catheter at three dose levels. Treatment with DFMO resulted in a time- and dose-dependent, cytostatic effect on the growth of the tumor. In fibrosarcoma-bearing rats the tumor putrescine levels were reduced after 6 and 12 days of DFMO treatment. Tumor spermidine levels were consistently reduced after 6 and 12 days of treatment with the reduction being dose dependent. The decrease in tumor ornithine decarboxylase activity was dose dependent. Erythrocyte putrescine levels were decreased in tumor- and non-tumor-bearing rats, suggesting that DFMO reduces the tumor contribution to the erythrocyte pool. Erythrocyte spermidine levels of fibrosarcoma- and non-tumor-bearing rats were elevated at the lower DFMO doses administered for 12 days but returned to normal as the dose was increased. Erythrocyte spermine levels were elevated in both groups of rats at all DFMO doses. Although normal host tissue weights were not affected by treatment with DFMO, the putrescine and spermidine levels of liver, spleen, and kidney and ornithine decarboxylase activity of the liver and kidney were decreased. These data demonstrate that i.v. DFMO has a cytostatic effect toward a rapidly growing fibrosarcoma associated with the depletion of both tumor putrescine and spermidine levels.
Kinin receptor expression during Staphylococcus aureus infection (2006)

An inappropriate host response to invading bacteria is a critical parameter that often aggravates the outcome of an infection. Staphylococcus aureus is a major human Gram-positive pathogen that causes a wide array of community- and hospital-acquired diseases ranging from superficial skin infections to severe conditions such as staphylococcal toxic shock. Here we find that S aureus induces inflammatory reactions by modulating the expression and response of the B1 and B2 receptors, respectively. This process is initiated by a chain of events, involving staphylococcal-induced cytokine release from monocytes, bacteria-triggered contact activation, and conversion of bradykinin to its metabolite desArg(9)bradykinin. The data of the present study implicate an important and previously unknown role for kinin receptor regulation in S aureus infections.
Material Transfer Recording (1970)

A material transfer technique for image recording is being developed that uses a focused laser beam to transfer ink from a substrate to a recording medium. No other processing is required; the recording is formed and developed merely by transfer and is instantly available for readout. This article relates some of the observed phenomena associated with transfer recording, discusses several test procedures directed toward the establishment of writing rate capabilities, presents the available test data, and offers suggested physical models to explain the observed transfer action.
Ground plane optimization for 20nm FDSOI transistors with thin Buried Oxide (2012)

Planar fully depleted (FD) devices with thin Buried Oxide (BOX) offer the unique ability to incorporate effective back biasing which is a key enabler to build a versatile multi-Vt technology. From a dynamic standpoint, forward back bias lowers Vt and thus boost device performance, whereas reverse back bias increases Vt and thus decreases leakage. From a static point of view the back gate allows fine Vt tuning. Here we propose and evaluate a back gate implant scheme that enables a full use of the back bias.
Heart motion adapted cine phase-contrast flow measurements through the aortic valve (1999)

A method for magnetic resonance cine velocity mapping through heart valves with adaptation of both slice offset and angulation according to the motion of the valvular plane of the heart is presented. By means of a subtractive labeling technique, basal myocardial markers are obtained and automatically extracted for quantification of heart motion at the valvular level. The captured excursion of the basal plane is used to calculate the slice offset and angulation of each required time frame for cine velocity mapping. Through-plane velocity offsets are corrected by subtracting velocities introduced by basal plane motion from the measured velocities. For evaluation of the method, flow measurements downstream from the aortic valve were performed both with and without slice adaptation in 11 healthy volunteers and in four patients with aortic regurgitation. Maximum through-plane motion at the aortic root level as calculated from the labeled markers averaged 8.9 mm in the volunteers and 6.5 mm in the patients. The left coronary root was visible in 2-4 (mean: 2.2) time frames during early diastole when imaging with a spatially fixed slice. Time frames obtained with slice adaptation did not contain the coronary roots. Motion correction increased the apparent regurgitant volume by 5.7 +/- 0.4 ml for patients with clinical aortic regurgitation, for an increase of approximately 50%. The proposed method provides flow measurements with correction for through-plane motion perpendicular to the aortic root between the valvular annulus and the coronary ostia throughout the cardiac cycle. Magn Reson Med 42:970-978, 1999.
A New Method for Sampling and Detection of Exhaled Respiratory Virus Aerosols (2007)

We have developed a mask sampler for exhaled respiratory viruses. Among a group of 9 patients with cold symptoms who had virus-positive nasal mucus specimens, as analyzed by multiplexed polymerase chain reaction, virus-positive mask samples were obtained after coughing (20 times), talking (20 min), or breathing (20 min) from 6, 5, and 3 patients, respectively.
Discretized estimator learning automata (1992)

The improvements gained by rendering the various estimator learning algorithms discrete are investigated. This is done by restricting the probability of selecting an action to a finite discrete subset of (0, 1). This modification is proven to be epsilon -optimal in all stationary environments. Various discretized estimator algorithms (DEAs) are constructed. Subsequently, members of the family of DEAs are shown to be epsilon -optimal by deriving two sufficient conditions required for the epsilon -optimality-the properties of monotonicity and moderation. A conjecture about the necessity of these conditions for epsilon -optimality is presented. Experimental results indicate that the discrete modifications improve the performance of the algorithms so that the automata constitute fast-converging and accurate learning automata.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Lasing characteristics of InGaAs-GaAs polarization controlled vertical-cavity surface-emitting laser grown on GaAs [311] B substrate (1999)

We have demonstrated an oxide confinement polarization controlled vertical-cavity surface-emitting laser (VCSEL) grown on a GaAs [311]B substrate. The polarization state was well controlled along the [2~33] crystal direction due to an anisotropic gain in the [311]B plane. We fabricated a small oxide aperture VCSEL with a threshold of 260 /spl mu/A and realized single-transverse mode and single-polarization operation for the first time. The sidemode suppression ratio (SMSR) was 35 dB and the orthogonal polarization suppression ratio (OPSR) was 25 dB. In addition, we have measured polarization and transverse mode characteristics of multi- and single-transverse mode devices under high-speed modulation. In the multimode device of 12 /spl mu/m/spl times/12 pm oxide aperture, we have achieved stable polarization operation of over 25-dB OPSR up to 10 Gb/s and have observed no power penalty due to polarization instability under 2.5-Gb/s pseudorandom modulation. The single-mode device showed stable single-transverse mode and polarization under the modulation conduction up to 5 GHz of sinusoidal modulation. SMSR and OPSR were over 30 and 10 dB, respectively.
Bi - S 계 쾌삭강의 고온연성에 대한 열간압연 및 Bi 의 영향 (1996)

An investigation was performed to examine the deformation behavior and the fracture mechanisms of Bi-S free machining steels at elevated temperatures. Especially, focus was paid on the effects of hot rolling and Bi content on the hot ductility and the fracture behavior of the present free machining steels. In order to find the effect of a hot rolling. experiments were conducted on the as-casted state and the as-rolled state, and their high temperature deformation behavior was compared Under the present experimental conditions, the as-rolled state exhibits better hot ductility than the as-casted state due to its homogeneous matrix microstructure. However, the hot ductility in both the as-rolled steels and the as-casted steels decreased with decreasing temperature. This ductility loss would be attributed to the embrittlement which is induced by the existence of a liquid metal, Bi, at testing temperatures. It was found that the hot ductility in the as-rolled steels at the temperature range from 1100℃ to 1050℃ primarily depended on the ductility of matrix, at temperature range from 1050℃ to 950℃ primarily depended on the absolute Bi content, and below 900℃ primarily depended on the liquid Bi film on the grain boundary rather than the absolute Bi content. The as-rolled state exhibited the transition of fracture mode from ductile dimple fracture to brittle fracture at a reduction of area of about 60%. The above results were discussed in the light of the mechanisms of a liquid metal induced embrittlement as well as the fracture mechanisms of low carbon steels.
Effect of a photonic band gap in the optical range on solid-state SiO2 cluster lattices — opals (1996)

It is shown that synthetic opals — cubic face-centered lattices of SiO2 clusters — are systems which exhibit a number of properties of photonic crystals in the visible-light range. By filling the voids (pores) in such lattices with different materials it is possible to vary the optical contrast of the medium and to obtain crystals of both the lattice of spheres type and its three-dimensional replica. It is shown that under conditions of identical optical contrast and in the presence of an additional optical inhomogeneity of the spheres, the transparency of the lattice of spheres is lower than that of its replica based on homogeneous media. A refractive index modulation of 1.266 was achieved in the lattice of spheres.
Timestamping schemes for MPEG-2 systems layer and their effect on receiver clock recovery (1999)

We propose and analyze several strategies for performing timestamping of an MPEG-2 Transport Stream transmitted over a packet-switched network using the PCR-unaware encapsulation scheme, and analyze their effect on the quality of the recovered clock at the MPEG-2 Systems decoder. When the timestamping scheme is based on a timer with a fixed period, the PCR values in the packet stream may switch polarity deterministically, at a frequency determined by the timer period and the transport rate of the MPEG signal. This, in turn, can degrade the duality of the recovered clock at the receiver beyond acceptable limits. We consider three timestamping schemes for solving this problem: (1) selecting a deterministic timer period to avoid the phase difference in PCR values altogether, (2) fine-tuning the deterministic timer period to maximize the frequency of PCR polarity changes, and (3) selecting the timer period randomly to eliminate the deterministic PCR polarity changes. For the case of deterministic timer period, we derive the frequency of the PCR polarity changes as a function of the timer period and the transport rate, and use it to find ranges of the timer period for acceptable quality of the recovered clock. We also analyze a random timestamping procedure based on a random telegraph process and obtain lower bounds on the rate of PCR polarity changes such that the recovered clock does not violate the PAL/NTSC clock specifications. The analytical results are verified by simulations with both synthetic and actual MPEG-2 Transport Streams sent to a simulation model of an MPEG-2 Systems decoder.
The Migration Behaviors of Individual Fe Adatom on Fe Nanoparticle (2014)

The migration behaviors of Fe adatom on Fe nanoparticles have been explored by the nudged elastic band (NEB) method. We take nanoparticle consisting of 2465 atoms as an example to illustrate the energy barriers and the migration pathways of Fe adatom on Fe nanoparticle. For the adatom at the three typical kinds of locations, the hopping mechanism is more favorable with the lowest barriers and the exchange mechanism requires relatively higher energies. For the single adatom far away from the interface region, a single adatom on each nanoparticle facet follows a migration behavior similar to that on a bcc surface. In the interface region, there is a competition between the direct crossing mechanism and the indirect crossing mechanism. In addition, the locations have obvious influences on the migration behaviors of the adatom and the effects are to some extent restricted by the migration mechanism.
New Image Processing Technique for Evaluating Breast Microcalcifications (2012)

MicroPure imaging identified significantly more breast microcalcifications than gray scale US.
Strong security for network-attached storage (2002)

We have developed a scheme to secure networkattached storage systems against many types of attacks. Our system uses strong cryptography to hide data from unauthorized users; someone gaining complete access to a disk cannot obtain any useful data from the system, and backups can be done without allowing the super-user access to cleartext. While insider denial-of-service attacks cannot be prevented (an insider can physically destroy the storage devices), our system detects attempts to forge data. The system was developed using a raw disk, and can be integrated into common file systems.
Effective Quality Control of Charpy Pendulum Impact Test (2010)

Through using standard impact specimens to verify the precision of the pendulum impact machine, and analyzing the fractured specimens that has been tested,a quick periodic check to the pendulum impact machine has been done.An apt solution shall be used when a bias factor of the Charpy pendulum impact test has been found. So a high precision of the Charpy pendulum impact test will be guaranteed and an effective quality control can be done at high level.
Two Rab proteins, vesicle-associated membrane protein 2 (VAMP-2) and secretory carrier membrane proteins (SCAMPs), are present on immunoisolated parietal cell tubulovesicles (1997)

The tubulovesicles of gastric parietal cells sequester H+/K+-ATPase molecules within resting parietal cells. Stimulation of parietal cell secretion elicits delivery of intracellular H+/K+-ATPase to the apically oriented secretory canaliculus. Previous investigations have suggested that this process requires the regulated fusion of intracellular tubulovesicles with the canalicular target membrane. We have sought to investigate the presence of critical putative regulators of vesicle fusion on immunoisolated gastric parietal cell tubulovesicles. Highly purified tubulovesicles were prepared by gradient fractionation and immunoisolation on magnetic beads coated with monoclonal antibodies against the alpha subunit of H+/K+-ATPase. Western blot analysis revealed the presence of Rab11, Rab25, vesicle-associated membrane protein 2 (VAMP-2) and secretory carrier membrane proteins (SCAMPs) on immunoisolated vesicles. The same cohort of proteins was recovered on vesicles immunoisolated with monoclonal antibodies against SCAMPs and VAMP-2. In contrast, whereas immunoreactivities for syntaxin 1A/1B and synaptosome-associated protein (SNAP-25) were present in gradient-isolated vesicles, none of the immunoreactivity was associated with immunoisolated vesicles. The observation of VAMP-2 and two Rab proteins on immunoisolated H+/K+-ATPase-containing tubulovesicles supports the role for tubulovesicles in a regulated vesicle fusion process. In addition, the presence of SCAMPs along with Rab11 and Rab25 implicates the tubulovesicles as a critical apical recycling vesicle population.