gebhart/patrepeval huggingface dataset:
Stability of a Speed Ratio Control Servo-mechanism for a Half-Toroidal Traction Drive CVT (1993)

A continuously variable power transmission, CVT, has potential for the improvement of fuel economy and cruising comfort as an automotive propulsion system. A traction drive CVT changes its speed ratio by the control of side slip force on the Hertzian contact. This mechanism has the features of equal torque transmission of every rolling element and low wasted power for the speed ratio change, but sometimes falls into self-excited vibration at higher rotating speed. This paper describes the principle of the speed ratio changing mechanism of a half-toroidal traction drive CVT and offers a compensatory measure for stabilizing the electrohydraulically operated speed ratio control servomechanism.
Polyaniline‐poly[p‐styrenesulfonic acid‐co‐methoxyoligo(ethylene glycol)acrylate] Composite Electrode for All‐Solid‐State Rechargeable Lithium Battery (1995)

Polyaniline‐poly[p‐styrenesulfonic acid‐co‐methoxyoligo(ethylene glycol)acrylate] Composite Electrode for All‐Solid‐State Rechargeable Lithium Battery, Tsutsumi, Hiromori, Fukuzawa, Shigeharu, Ishikawa, Masashi, Morita, Masayuki, Matsuda, Yoshiharu
MAG and OMgp Synergize with Nogo-A to Restrict Axonal Growth and Neurological Recovery after Spinal Cord Trauma (2010)

Functional recovery after adult CNS damage is limited in part by myelin inhibitors of axonal regrowth. Three molecules, Nogo-A, MAG, and OMgp, are produced by oligodendrocytes and share neuronal receptor mechanisms through NgR1 and PirB. While each has an axon-inhibitory role in vitro, their in vivo interactions and relative potencies have not been defined. Here, we compared mice singly, doubly, or triply mutant for these three myelin inhibitor proteins. The myelin extracted from Nogo-A mutant mice is less inhibitory for axons than is that from wild-type mice, but myelin lacking MAG and OMgp is indistinguishable from control. However, myelin lacking all three inhibitors is less inhibitory than Nogo-A-deficient myelin, uncovering a redundant and synergistic role for all three proteins in axonal growth inhibition. Spinal cord injury studies revealed an identical in vivo hierarchy of these three myelin proteins. Loss of Nogo-A allows corticospinal and raphespinal axon growth above and below the injury, as well as greater behavioral recovery than in wild-type or heterozygous mutant mice. In contrast, deletion of MAG and OMgp stimulates neither axonal growth nor enhanced locomotion. The triple-mutant mice exhibit greater axonal growth and improved locomotion, consistent with a principal role for Nogo-A and synergistic actions for MAG and OMgp, presumably through shared receptors. These data support the hypothesis that targeting all three myelin ligands, as with NgR1 decoy receptor, provides the optimal chance for overcoming myelin inhibition and improving neurological function.
Laser subepithelial keratomileusis: electron microscopy and visual outcomes of flap photorefractive keratectomy (2001)

Laser epithelial keratomileusis (LASEK) is a surgical technique that may be performed in patients with low myopia who are considering conventional photorefractive keratectomy (PRK), in patients with thin corneas, and in patients with professions or lifestyles that predispose them to trauma. Ethanol (18%) is applied for 25 seconds and a hinged epithelial flap is created. After laser ablation, the flap is repositioned over the ablated stroma. Our data showed that epithelial defects occurred in 63% eyes on Day 1. Postoperative pain was absent in 47%. Uncorrected visual acuity of 20/40 or better was achieved in all patients at 1 week. Data from several studies suggest that LASEK may reduce postoperative pain and corneal haze associated with PRK. LASEK offers the potential advantage of avoiding flap-related complications associated with laser in situ keratomileusis and decreasing postoperative pain and corneal scarring associated with PRK. Long-term studies are needed to confirm these potential advantages and to determine the safety, efficacy, and predictability of this surgical technique.
Acid phosphatases (2002)

Acid phosphatases (APs) are a family of enzymes that are widespread in nature, and can be found in many animal and plant species. Mystery surrounds the precise functional role of these molecular facilitators, despite much research. Yet, paradoxically, human APs have had considerable impact as tools of clinical investigation and intervention. One particular example is tartrate resistant acid phosphatase, which is detected in the serum in raised amounts accompanying pathological bone resorption. This article seeks to explore the identity and diversity of APs, and to demonstrate the relation between APs, human disease, and clinical diagnosis.
Metalorganic Molecular Beam Epitaxial Growth of ZnSe Using Diethylzinc and Diethylselenide (1986)

ZnSe epitaxial layers have been grown for the first time on (100) GaAs substrates by metalorganic molecular beam epitaxy using diethylzinc and diethylselenide. Diethylselenide is cracked by the cracking furnace. Smooth single-crystalline layers can be grown at substrate temperatures above 200°C. Photoluminescence spectra vary noticeably with the substrate temperature. Above 400°C, the spectra measured at 71 K were dominated by intense blue donor-acceptor pair bands, and broad luminescence bands at longer wavelengths were weak.
Live-wire Method With FCM Classification (2006)

This document describes modification of the live-wire algorithm also known as the intelligent scissors. This tool is utilized to interactive segmentation of the digitized images. Unfortunately, traditional live-wire algorithm suffers from high computational cost and is time consuming method, highly dependent on image size. Numerical complexity follows that live-wire algorithm takes all image pixels into consideration but only some pixels are situated on the edges in image. In connection with this fact in this paper condition of essential pixels is proposed. FCM algorithm utilized to classification of image pixels is proposed to describe this condition. This modification significantly shortens computational time. Obtained results will be presented based on medical images from magnetic resonance imaging (MRI) or computer tomography (CT). However this method is not limited only to medical or black and white images
Intentional query suggestion (2009)

The degree to which users' make their search intent explicit can be assumed to represent an upper bound on the level of service that search engines can provide. In a departure from traditional query expansion mechanisms, we introduce Intentional Query Suggestion as a novel idea that is attempting to make users' intent more explicit during search. In this paper, we present a prototypical algorithm for Intentional Query Suggestion and we discuss corresponding data from comparative experiments with traditional query suggestion mechanisms. Our preliminary results indicate that intentional query suggestions 1) diversify search result sets (i.e. it reduces result set overlap) and 2) have the potential to yield higher click-through rates than traditional query suggestions.
Array-fed reflector antenna design and applications (1981)

One phase of the spacecraft antenna research carried out at the Jet Propulsion Laboratory for deep space and near-earth communications is described. Array-fed reflector antenna designs have been elaborated for beam scanning, power amplification, and multiple beam applications. The antenna designs derive from similar optical concepts. Each antenna comprises a relatively small plane-wave array feeding a near-field dual-reflector system. The main reflector and the the subreflector are confocal paraboloids having identical focal length to diameter ratios. The array feed is positioned in such a way that the subreflector is in the near-field (collimated beam) region of the feed. The field distribution of the feed aperture is thereby recreated approximately in the main reflector aperture. The detailed design concepts of the antennas (beam-scanning, high-power, and mutliple-beam) are discussed, and the calculated and measured RF performances of the antennas are presented.
ADAPT: Efficient workload-sensitive flash management based on adaptation, prediction and aggregation (2012)

Solid-state drives (SSDs) made of flash memory are widely utilized in enterprise servers nowadays. Internally, the management of flash memory resources is done by an embedded software known as the flash translation layer (FTL). One important function of the FTL is to map logical addresses issued by the operating system into physical flash addresses. The efficiency of this address mapping in the FTL directly impacts the performance of SSDs. In this paper, we propose a hybrid mapping FTL scheme, called Aggregated Data movement Augmenting Predictive Transfers (ADAPT). ADAPT observes access behaviors online to handle both sequential and random write requests efficiently. It also takes advantage of locality revealed in the history of recent accesses to avoid unnecessary data movements in the required merge process. More importantly, by these mechanisms, ADAPT can adapt to various workloads to achieve good performance. Experimental results show that ADAPT is as much as 35.4%, 44.2% and 23.5% faster than a state-of-the-art hybrid mapping scheme, a prevalent page-based mapping scheme, and a latest workload-adaptive mapping scheme, respectively, with a small increase in space requirement.
Energy-efficient floating-point arithmetic for digital signal processors (2011)

Emerging image and signal processing applications involve several matrix-based algorithms that are extremely sensitive to round-off error in computations. Implementing these applications on fixed-point (FxP) processors can significantly increase their design-time and may also result in reduced signal-to-noise (SNR) ratios. However, due to the high area and power overhead of floating-point (FP) hardware, low-power DSPs typically do not provide hardware support for floating-point (FP) arithmetic. Moreover, the long latency of FP operations can also reduce the performance of executing signal processing applications. In this paper, we propose a block-floating-point-based fused multiply-add (BFP-FMA) unit with reduced area and power overhead that is tailored to the needs of signal processing applications. Since dot-product instructions are commonly employed in matrix-based kernels, we employ our proposed BFPFMA unit to reduce the latency of dot-product operations by a factor of two. Our proposed FMA unit can improve the performance of executing key DSP kernels by as much as 40%, while reducing energy consumption by 28%. Exploiting BFP arithmetic also allows us to reduce the area and power of the FMA units by 33% and 41%, respectively.
Effect of 'delta tabs' on mixing and axis switching in jets from asymmetric nozzles (1994)

The effect of delta tabs on mixing and the phenomenon of axis switching in free air jets from various asymmetric nozzles was studied experimentally. Flow visualization and Pitot probe surveys were carried out with a set of small nozzles (D = 1.47 cm) at a jet Mach number, Mj = 1.63. Hot wire measurements for streamwise vorticity were carried out with larger nozzles (D = 6.35 cm) at Mj = 0.31. Jet mixing with the asymmetric nozzles, as indicated by the mass fluxes downstream, was found to be higher than that produced by a circular nozzle. The circular nozzle with four delta tabs, however, produced fluxes much higher than that produced by a asymmetric nozzles themselves or by most of the tab configurations tried with them. Even higher fluxes could be obtained with only a few cases, e.g., with 3:1 rectangular nozzle with two large delta tabs placed on the narrow edges. In this case, the jet 'fanned out' at a large angle after going through one axis switch. The axis switching could be either stopped or augmented with suitable choice of the tab configurations. Two mechanisms are identified governing the phenomenon. One, as described in Ref. 12 and referred to here as the omega(sub Theta)-induced dynamics, is due to differential induced velocities of different segments of a rolled up azimuthal vortical structure. The other is the omega(sub x)-induced dynamics due to the induced velocities of streamwise vortex pairs in the flow. While the former dynamics are responsible for rapid axis switching in periodically forced jets, the effect of the tabs is governed mainly by the latter. It is inferred that both dynamics are active in a natural asymmetric jet issuing from a nozzle having an upstream contraction. The tendency for axis switching caused by the omega(sub Theta)-induced dynamics is resisted by the omega(sub x)-induced dynamics, leading to a delayed or no switch over in that case. In jets from orifices and in screeching jets, the omega(sub Theta)-induced dynamics dominate causing a faster switch over.
Big Data Bioinformatics (2014)

Recent technological advances allow for high throughput profiling of biological systems in a cost-efficient manner. The low cost of data generation is leading us to the "big data" era. The availability of big data provides unprecedented opportunities but also raises new challenges for data mining and analysis. In this review, we introduce key concepts in the analysis of big data, including both "machine learning" algorithms as well as "unsupervised" and "supervised" examples of each. We note packages for the R programming language that are available to perform machine learning analyses. In addition to programming based solutions, we review webservers that allow users with limited or no programming background to perform these analyses on large data compendia.
Heritability and Tissue Specificity of Expression Quantitative Trait Loci (2006)

Variation in gene expression is heritable and has been mapped to the genome in humans and model organisms as expression quantitative trait loci (eQTLs). We applied integrated genome-wide expression profiling and linkage analysis to the regulation of gene expression in fat, kidney, adrenal, and heart tissues using the BXH/HXB panel of rat recombinant inbred strains. Here, we report the influence of heritability and allelic effect of the quantitative trait locus on detection of cis- and trans-acting eQTLs and discuss how these factors operate in a tissue-specific context. We identified several hundred major eQTLs in each tissue and found that cis-acting eQTLs are highly heritable and easier to detect than trans-eQTLs. The proportion of heritable expression traits was similar in all tissues; however, heritability alone was not a reliable predictor of whether an eQTL will be detected. We empirically show how the use of heritability as a filter reduces the ability to discover trans-eQTLs, particularly for eQTLs with small effects. Only 3% of cis- and trans-eQTLs exhibited large allelic effects, explaining more than 40% of the phenotypic variance, suggestive of a highly polygenic control of gene expression. Power calculations indicated that, across tissues, minor differences in genetic effects are expected to have a significant impact on detection of trans-eQTLs. Trans-eQTLs generally show smaller effects than cis-eQTLs and have a higher false discovery rate, particularly in more heterogeneous tissues, suggesting that small biological variability, likely relating to tissue composition, may influence detection of trans-eQTLs in this system. We delineate the effects of genetic architecture on variation in gene expression and show the sensitivity of this experimental design to tissue sampling variability in large-scale eQTL studies.
Generation of radical oxygen species by neural crest cells treated in vitro with isotretinoin and 4-oxo-isotretinoin. (1990)

The effects of isotretinoin (IR) and its primary metabolite (in the human), 4-oxo-isotretinoin (4-OIR or OIR), on isolated chick neural crest cells (NCC's) in culture were studied. NCC's were found to be deficient in both superoxide dismutase (SOD) and catalase, two of the enzymes known to function in the "scavenging" (dismutation) of toxic radical oxygen species (ROS) such as the superoxide anion and hydrogen peroxide. The addition of IR or OIR to the culture medium significantly depressed the viability of the NCC's when compared to untreated cells. OIR was more potent in this regard than IR. In the presence of either IR or OIR, NCC's generated superoxide anions (O2.), hydrogen peroxide (H2O2), and hydroxyl anions (OH.). OIR was again more potent. The cytotoxicity of IR or OIR was demonstrated by the "leakage" of radioactive chromium from prelabeled cells. The latter is suggestive of a primary surface membrane defect, most logically via the induction of lipid peroxides by the retinoids. The latter is accompanied by an increase in membrane permeability and porosity as evidenced by the fact that various fluorescently labeled molecules, including BSA-FITC (MW 69,000), gain entrance into the cytoplasm of the retinoid treated cells. No label was seen in the cytoplasm of similarly treated control cells. When SOD (200 units/ml) or catalase (400 units/ml) was added to the culture media of IR- or OIR-treated NCCs, cell viability was increased and the concentration of the various ROS generated was decreased. Membrane leakiness to chromium and FITC-BSA was also decreased in the presence of these enzymes. Free radicals, when not inactivated (dismutated), are known to be pathobiotic to most cells. Cell membranes are at a particular high risk from ROS which induce structural, physiological, and biochemical alterations in the cell membrane. The latter can have a negative effect on cell permeability, maintenance of normal ionic gradients, membrane enzyme activity, cell-to-cell communication, etc. Such defects can ultimately culminate in hypoplasia, aplasia, and cell necrosis. This study has shown that NCC's may be overtly sensitive to ROS, especially since these undifferentiated cells apparently lack inherent SOD and/or catalase activity. From this study it appears as if both IR and OIR perturb the normal functional state of NCC's by "triggering" the generation of ROS. This may certainly explain the teratogenicity of these drugs as related to the viability of neural crest derived ectomesenchymal cells and normal craniofacial morphogenesis.
Scanning holography and two-dimensional image processing by acousto-optic two-pupil synthesis (1985)

An implementation of an acousto-optic heterodyning image processor was reported earlier [ Opt. Lett.4, 317 ( 1979)]. However, details of that report are limited only to the confirmation of the basic principle of operation. In this paper, we present and emphasize the mathematical structure of the processor. We also compare this processor with other kinds of scanning and nonscanning processors. The analysis is then extended to the defocused case, where the optical transfer function is derived. A potential application of this in scanning holography is discussed.
Objective view synthesis quality assessment (2012)

View synthesis brings geometric distortions which are not handled efficiently by existing image quality assessment metrics. Despite the widespread of 3-D technology and notably 3D television (3DTV) and free-viewpoints television (FTV), the field of view synthesis quality assessment has not yet been widely investigated and new quality metrics are required. In this study, we propose a new full-reference objective quality assessment metric: the View Synthesis Quality Assessment (VSQA) metric. Our method is dedicated to artifacts detection in synthesized view-points and aims to handle areas where disparity estimation may fail: thin objects, object borders, transparency, variations of illumination or color differences between left and right views, periodic objects... The key feature of the proposed method is the use of three visibility maps which characterize complexity in terms of textures, diversity of gradient orientations and presence of high contrast. Moreover, the VSQA metric can be defined as an extension of any existing 2D image quality assessment metric. Experimental tests have shown the effectiveness of the proposed method.
Kinematic Control of Redundant Knuckle Booms (2009)

Abstract The Swedish forestry industry competes on an international market; because raw material is more expensive than in other parts of the world, the chain from the stump to the industry needs to be very effective. One part in this chain is cutting and transporting trees from the forest to the landing area for further transportation with trucks to the paper or saw mill. When cutting and transporting trees, forestry machines equipped with booms are used to handle the trees. If boom handling time can be reduced thereby increasing productivity by 10 percent, the Swedish forestry industry can earn up to 250 million Swedish crowns (US$35 million) per year. One way to decrease boom handling time is to introduce automatization. This paper describes how to solve the kinematic control of knuckle booms used on forestry machines when automatization is introduced. The objective was to develop a kinematic control strategy for maximum lifting capacity, which is suited for computer-controlled knuckle booms that are redundant. This strategy was analyzed with respect to time consumption when the manipulator tip moves along a predetermined path. The analysis was conducted on a knuckle boom used on a forwarder in a forestry application. The knuckle boom had one redundant degree of freedom. The analysis showed the necessary joint speed requirements and time consumption for certain motion cycles and also what happens when the joints reach their maximum velocity limits.
A splice-junction mutation responsible for familial apolipoprotein A-II deficiency. (1990)

The first case of familial apolipoprotein A-II (apo A-II) deficiency was recently reported from Hiroshima, Japan, and designated apo A-IIHiroshima. The proband had no immunologically detectable apo A-II in her plasma. DNA sequence analysis showed that the proband was homozygous for a G----A transition at position 1 of intron 3 of the apo A-II gene. A sister of the proband, who had an intermediate level of plasma apo AII, was shown to be heterozygous for this base substitution. This splice-junction alteration is most likely responsible for apo A-II deficiency, since it would be expected to completely block splicing of intron 3 from the primary transcript and therefore prevent formation of functional mRNA. This deficiency seems to have little influence either on lipid and lipoprotein profiles or on the occurrence of coronary artery disease.
Evaluating text preprocessing to improve compression on maillogs (2009)

Maillogs contain important information about mail which has been sent or received. This information can be used for statistical purposes, to help prevent viruses or to help prevent SPAM. In order to satisfy regulations and follow good security practices, maillogs need to be monitored and archived. Since there is a large quantity of data, some form of data reduction is necessary. Data compression programs such as gzip and bzip2 are commonly used to reduce the quantity of data. Text preprocessing can be used to aid the compression of English text files. This paper evaluates whether text preprocessing, particularly word replacement, can be used to improve the compression of maillogs. It presents an algorithm for constructing a dictionary for word replacement and provides the results of experiments conducted using the ppmd, gzip, bzip2 and 7zip programs. These tests show that text preprocessing improves data compression on maillogs. Improvements of up to 56 percent in compression time and up to 32 percent in compression ratio are achieved. It also shows that a dictionary may be generated and used on other maillogs to yield reductions within half a percent of the results achieved for the maillog used to generate the dictionary.