gebhart/patrepeval huggingface dataset:
Remanence stability and magnetic fabric development in synthetic shear zones deformed at 500°C (2010)

Shear experiments were performed on magnetite‐bearing calcite aggregates to examine magnetic fabric development and remanence stability in a deforming system using elevated temperature and pressure to encourage deformation by crystal‐plastic processes. Samples composed of 1 wt % pseudo‐single‐domain magnetite (1–2 μ m) in a calcite matrix were created with either strong or weak initial fabrics and deformed in coaxial simple shear to strains up to γ = 1.5 at constant strain rates between 6 × 10 −5 and 1 × 10 −4 s −1 at 500°C and confining pressure of 300 MPa. Samples were given weak field thermal remanent magnetizations prior to deformation. Demagnetization of postdeformation remanence reveals that a primary remanent magnetization can withstand deformation at pressures and temperatures approximately equivalent to greenschist facies metamorphic conditions on laboratory time scales, but this stability is found to depend on the character of the predeformation fabric. The origin of secondary remanence components acquired during deformation is uncertain but is likely to partially result from thermal viscous remagnetization. Complete postdeformation remagnetization in initially anisotropic samples appears to involve a stress‐softening or piezoremanent magnetization mechanism. Postdeformation anisotropy measurements show progressive changes in magnetic fabric strength with strain. In the absence of a strong initial magnetic anisotropy, magnetic fabric intensity increases linearly as a function of strain; however, deformation that overprinted an existing fabric results in an apparent decrease of the initial anisotropy at low strains followed by rapid increases in magnetic fabric strength with increasing strain. Our results underscore the important role that initial fabric can play in determining the character of deformation fabrics.
Evaluation of AC axial magnetic fields needed to prevent anode spots in vacuum arcs between opening contacts (1994)

The influence of AC axial magnetic (AM) fields on the development of half-cycle drawn vacuum arcs is described. A Helmholtz coil provided an independent AC AM field B/sub ax//sup ac/ in the opening gap between flat profile, butt type, Cr-Cu contacts. For peak arc currents I/sub p/ up to 20 kA, critical AM fields B/sub crit//sup ac/ were determined, which prevented anode involvement. The dependence of B/sub crit//sup ac/ on I/sub p/ is compared with the analogous dependence using constant AM fields B/sub ax//sup DC/. These results extend the usefulness of the B/sub crit/ parameter to the design of contact structures for producing self-generated AM fields from the AC arcing current. A similar direct transition to the high-current diffuse arc mode can be maintained over the half-cycle without an imposed B/sub ax/ if I/sub p/>
The CCR4 gene from Saccharomyces cerevisiae is required for both nonfermentative and spt-mediated gene expression. (1990)

Mutations in the yeast CCR4 gene inhibit expression of the glucose-repressible alcohol dehydrogenase (ADH2), as well as other nonfermentative genes, and suppress increased ADH2 expression caused by the cre1 and cre2 alleles. Both the cre1 and ccr4 alleles were shown to affect ADH II enzyme activity by altering the levels of ADH2 mRNA. Mutations in either CRE1 or CRE2 bypassed the inhibition of ADH2 expression caused by delta insertions at the ADH2 promoter which displace the ADH2 activation sequences 336 bp upstream of the TATA element. These cre1 and cre2 effects were suppressible by the ccr4 allele. The cre1 and ccr4 mutations also affected ADH2 expression when all the ADH2 regulatory sequences upstream of the TATA element were deleted. The relationship of the CRE genes to the SPT genes, which when mutated are capable of bypassing the inhibition of HIS4 expression caused by a delta promoter insertion (his4-912 delta allele), was examined. Both the cre1 and cre2 mutations allowed his4-912 delta expression. ccr4 mutations were able to suppress the ability of the cre alleles to increase his4-912 delta expression. CRE2 was shown to be allelic to the SPT6 gene, and CRE1 was found to be allelic to SPT10. We suggest that the CRE genes comprise a general transcriptional control system in yeast that requires the function of the CCR4 gene.
Multiphase Pressure Pulses for Quick-Acting Valves: Offshore Testing (1999)

Abstract Offshore tests were performed by quickly closing a valve by the wellhead. The rapid pressure signals, created by this valve closure, were registered at three different locations upstream of the valve. The effective actuation time of the valve was about. 0.5 second. The tests concluded that the velocity of sound in the multiphase mixture could be predicted using a homogeneous assumption. The pressure waves were attenuated because of friction, but also chokes and bends were important attenuation mechanisms for the rapid pressure waves in multiphase flow.
Dispositivo para la producción de nanopartículas a través de un proceso con plasma (1999)

Este trabajo presenta un dispositivo destinado a la producción de nanopartículas utilizando métodos de vaporización de metales y/o el método de descomposición de compuestos metálicos (óxidos, carbonatos, halógenos) en el plasma del arco transferido o en el chorro de plasma. Se presentan algunas posibles aplicaciones. Las dimensiones de las partículas obtenidas varían entre 3 y 100nm.
Cell Fate Determination Factor DACH1 Inhibits c-Jun–induced Contact-independent Growth (2006)

The cell fate determination factor DACH1 plays a key role in cellular differentiation in metazoans. DACH1 is engaged in multiple context-dependent complexes that activate or repress transcription. DACH1 can be recruited to DNA via the Six1/Eya bipartite transcription (DNA binding/coactivator) complex. c-Jun is a critical component of the activator protein (AP)-1 transcription factor complex and can promote contact-independent growth. Herein, DACH1 inhibited c-Jun-induced DNA synthesis and cellular proliferation. Excision of c-Jun with Cre recombinase, in c-jun(f1/f1) 3T3 cells, abrogated DACH1-mediated inhibition of DNA synthesis. c-Jun expression rescued DACH1-mediated inhibition of cellular proliferation. DACH1 inhibited induction of c-Jun by physiological stimuli and repressed c-jun target genes (cyclin A, beta-PAK, and stathmin). DACH1 bound c-Jun and inhibited AP-1 transcriptional activity. c-jun and c-fos were transcriptionally repressed by DACH1, requiring the conserved N-terminal (dac and ski/sno [DS]) domain. c-fos transcriptional repression by DACH1 requires the SRF site of the c-fos promoter. DACH1 inhibited c-Jun transactivation through the delta domain of c-Jun. DACH1 coprecipitated the histone deacetylase proteins (HDAC1, HDAC2, and NCoR), providing a mechanism by which DACH1 represses c-Jun activity through the conserved delta domain. An oncogenic v-Jun deleted of the delta domain was resistant to DACH1 repression. Collectively, these studies demonstrate a novel mechanism by which DACH1 blocks c-Jun-mediated contact-independent growth through repressing the c-Jun delta domain.
Phenylbutyl Isoselenocyanate Modulates Phase I and II Enzymes and Inhibits 4-(Methylnitrosamino)-1-(3-Pyridyl)- 1-Butanone–Induced DNA Adducts in Mice (2011)

Lung cancer remains one of the most preventable forms of cancer with about 90% of cases attributed to cigarette smoking. Over the years, the development of chemopreventive agents that could inhibit, delay, or reverse the lung carcinogenesis process has been an active field of research, however, without much attainment. Through extensive structure-activity relationship studies, we recently identified a novel agent phenylbutyl isoselenocyanate (ISC-4), designed on the basis of naturally occurring isothiocyanates well known for their lung cancer prevention properties, as a potential chemopreventive agent. In this study, we used A/J mice to evaluate the lung cancer chemopreventive potential of ISC-4. A single intragastric dose of 1.25 μmol ISC-4 resulted in a time-dependent increase of selenium levels in serum, liver, and lung, suggesting that ISC-4 is orally bioavailable, a key requirement for a chemopreventive agent. This dose also resulted in a time-dependent inhibition of microsomal cytochrome P450 (Cyp450) activity and delayed increases in phase II UDP-glucuronyl transferase (Ugt) and glutathione-S-transferase (Gst) activity. ISC-4 was able to induce mRNA expression of Cyp, Ugt, and Gst enzyme isoforms in liver, but in lung, it inhibited Cyp isoforms while inducing Ugt and Gst isoforms. In addition, ISC-4 effectively inhibited methyl-DNA adduct formation in mice fed diet supplemented with ISC-4 for two weeks and then treated with the tobacco procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. These results suggest that ISC-4 is a strong candidate for development as a chemopreventive agent.
A Novel Method for the Design of Proximity Sensor Configuration for Rotor Blade Tip Timing (2018)

Blade tip timing (BTT) is a noncontact method for measuring turbomachinery blade vibration. Proximity sensors are mounted circumferentially around the turbomachine casing and used to measure the tip displacements of blades during operation. Tip deflection data processing is nontrivial due to complications such as aliasing and high levels of noise. Specialized BTT algorithms have been developed to extract the utmost amount of information from the signals. The effectiveness of these algorithms is, however, influenced by the circumferential spacing between the proximity sensors. If the spacing is suboptimal, an algorithm can fail to measure dangerous blade vibration. This paper presents a novel optimization approach that determines the optimal spacing between proximity sensors.
Vertex-Frequency Analysis on Graphs (2013)

One of the key challenges in the area of signal processing on graphs is to design dictionaries and transform methods to identify and exploit structure in signals on weighted graphs. To do so, we need to account for the intrinsic geometric structure of the underlying graph data domain. In this paper, we generalize one of the most important signal processing tools - windowed Fourier analysis - to the graph setting. Our approach is to first define generalized convolution, translation, and modulation operators for signals on graphs, and explore related properties such as the localization of translated and modulated graph kernels. We then use these operators to define a windowed graph Fourier transform, enabling vertex-frequency analysis. When we apply this transform to a signal with frequency components that vary along a path graph, the resulting spectrogram matches our intuition from classical discrete-time signal processing. Yet, our construction is fully generalized and can be applied to analyze signals on any undirected, connected, weighted graph.
Accuracy and timing aspects of location information based on signal-strength measurements in Bluetooth (2006)

Accurate positioning of wireless devices using short-range link-technologies is interesting for a number of applications including tracking, location-based services, and context sensitive networking. In this paper, accuracy and timing aspects for an indoor positioning method based on triangulation using signal strength measurements of Bluetooth links are analyzed experimentally and via simulation models. In the approach chosen in this paper, the delay to obtain signal strength measurements is determined by complex interactions of the Bluetooth inquiry procedure, which are analyzed in detailed simulation experiments. The location accuracy analysis is performed experimentally for the setting of an indoor corridor scenario including multi-path propagation properties
Treatment for small cell lung cancer, where are we now?-a review. (2016)

Small cell lung cancer (SCLC) represents between 13% and 15% of all diagnosed lung cancers worldwide. It is an aggressive neoplasia, with a 5-year mortality of 90% or more. It has historically been classified as limited disease (LD) and extensive disease (ED) in most study protocols. The cornerstone of treatment for any stage of SCLC is etoposide-platinum based chemotherapy; in limited stage (LS), concomitant radiotherapy to thorax and mediastinum. Prophylactic radiotherapy to the central nervous system (CNS) [prophylactic cerebral irradiation (PCI)] has diminished the incidence of brain metastasis as the site for relapse in LD and ED patients, therefore it should be offered to patients with complete response to induction first-line treatment. Regarding second-line treatment, results are more modest and topotecan is accepted as treatment for this scenario offering a modest benefit.
Length Effect on Ductility of Concrete in Uniaxial and Flexural Compression (2004)

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Hydrogen passivation of large-area polycrystalline silicon solar cells by high-current ion implantation (1988)

The fabrication of highly efficient, large-area polycrystalline silicon solar cells using ion implantation as a hydrogen passivation technique is presented. The development of a high-current ion implanter with a bucket-type ion source to hydrogenate crystal defects in cast polycrystalline cells is also presented. Effective hydrogen passivation of the defects is realized by implanting hydrogen ions into the back surface of the cells and increasing the hydrogen ion energy and dose. The results show that the polycrystalline cells exhibit a high conversion efficiency of 15.2% for a large area of 100 cm/sup 2/.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Keyboard acoustic emanations revisited (2005)

We examine the problem of keyboard acoustic emanations. We present a novel attack taking as input a 10-minute sound recording of a user typing English text using a keyboard, and then recovering up to 96% of typed characters. There is no need for a labeled training recording. Moreover the recognizer bootstrapped this way can even recognize random text such as passwords: In our experiments, 90% of 5-character random passwords using only letters can be generated in fewer than 20 attempts by an adversary; 80% of 10-character passwords can be generated in fewer than 75 attempts. Our attack uses the statistical constraints of the underlying content, English language, to reconstruct text from sound recordings without any labeled training data. The attack uses a combination of standard machine learning and speech recognition techniques, including cepstrum features, Hidden Markov Models, linear classification, and feedback-based incremental learning.
An autosomal genetic linkage map of the sheep genome. (1995)

We report the first extensive ovine genetic linkage map covering 2070 cM of the sheep genome. The map was generated from the linkage analysis of 246 polymorphic markers, in nine three-generation full-sib pedigrees, which make up the AgResearch International Mapping Flock. We have exploited many markers from cattle so that valuable comparisons between these two ruminant linkage maps can be made. The markers, used in the segregation analyses, comprised 86 anonymous microsatellite markers derived from the sheep genome, 126 anonymous microsatellites from cattle, one from deer, and 33 polymorphic markers of various types associated with known genes. The maximum number of informative meioses within the mapping flock was 222. The average number of informative meioses per marker was 140 (range 18-209). Linkage groups have been assigned to all 26 sheep autosomes.
Prettyprinting (1980)

An algorithm for prettyprinting is given. For an input stream of length n and an output device with linewidth m , the algorithm requires time O ( n ) and space O ( m ). The algorithm is described in terms of two parallel processes: the first scans the input stream to determine the space required to print logical blocks of tokens; the second uses this information to decide where to break lines of text; the two processes communicate by means of a buffer of size O ( m ). The algorithm does not wait for the entire stream to be input, but begins printing as soon as it has received a full line of input. The algorithm is easily implemented.
Joint virtual machine and bandwidth allocation in software defined network (SDN) and cloud computing environments (2014)

Cloud computing provides users with great flexibility when provisioning resources, with cloud providers offering a choice of reservation and on-demand purchasing options. Reservation plans offer cheaper prices, but must be chosen in advance, and therefore must be appropriate to users' requirements. If demand is uncertain, the reservation plan may not be sufficient and on-demand resources have to be provisioned. Previous work focused on optimally placing virtual machines with cloud providers to minimize total cost. However, many applications require large amounts of network bandwidth. Therefore, considering only virtual machines offers an incomplete view of the system. Exploiting recent developments in software defined networking (SDN), we propose a unified approach that integrates virtual machine and network bandwidth provisioning. We solve a stochastic integer programming problem to obtain an optimal provisioning of both virtual machines and network bandwidth, when demand is uncertain. Numerical results clearly show that our proposed solution minimizes users' costs and provides superior performance to alternative methods. We believe that this integrated approach is the way forward for cloud computing to support network intensive applications.
Probing the Structure−Function Relationship of Polyene Macrolides:  Engineered Biosynthesis of Soluble Nystatin Analogues (2006)

Although polyene macrolides are efficient antifungal agents with fungicidal mode of action, their use in medical practice is problematic due to their low solubility and significant human toxicity. In an attempt to address the solubility problem, we have obtained two analogues of nystatin with hydroxy groups at positions C31 and C33 through manipulation of the nystatin polyketide synthase in the producing organism Streptomyces noursei. Structures of the analogues were confirmed by nuclear magnetic resonance (NMR), and their solubility was found to be more than 2000 times higher than that of nystatin. However, both analogues were shown to have lost antifungal activity, implying that the integrity of the hydrophobic polyene region of the nystatin molecule is crucial for the fungicidal action. NMR data and computer modeling performed for the new analogues suggested conformational changes together with a significantly increased structural disorder, which may account for both increased solubility and the loss of activity.
Segmentation and tracking of faces in color images (2002)

The authors present a new approach for automatically segmentation and tracking of faces in color images. Segmentation of faces is performed by evaluating color and shape information. First, skin-like regions are determined based on the color attributes hue and saturation. Then regions with elliptical shape are selected as face hypotheses. They are verified by searching for facial features in their interior. After a face is reliably detected it is tracked over time. Tracking is realized by using an active contour model. The exterior forces of the snake are defined based on color features. They push or pull snaxels perpendicular to the snake. Results for tracking are shown for an image sequence consisting of 150 frames.
Individual Colorimetric Observer Model (2016)

This study proposes a vision model for individual colorimetric observers. The proposed model can be beneficial in many color-critical applications such as color grading and soft proofing to assess ranges of color matches instead of a single average match. We extended the CIE 2006 physiological observer by adding eight additional physiological parameters to model individual color-normal observers. These eight parameters control lens pigment density, macular pigment density, optical densities of L-, M-, and S-cone photopigments, and λmax shifts of L-, M-, and S-cone photopigments. By identifying the variability of each physiological parameter, the model can simulate color matching functions among color-normal populations using Monte Carlo simulation. The variabilities of the eight parameters were identified through two steps. In the first step, extensive reviews of past studies were performed for each of the eight physiological parameters. In the second step, the obtained variabilities were scaled to fit a color matching dataset. The model was validated using three different datasets: traditional color matching, applied color matching, and Rayleigh matches.
Photoinduced biochemical activity of fullerene carboxylic acid (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhotoinduced biochemical activity of fullerene carboxylic acidHidetoshi Tokuyama, Shigeru Yamago, Eiichi Nakamura, Takashi Shiraki, and Yukio SugiuraCite this: J. Am. Chem. Soc. 1993, 115, 17, 7918–7919Publication Date (Print):August 1, 1993Publication History Published online1 May 2002Published inissue 1 August 1993https://pubs.acs.org/doi/10.1021/ja00070a064https://doi.org/10.1021/ja00070a064research-articleACS PublicationsRequest reuse permissionsArticle Views2130Altmetric-Citations535LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Impairment aware routing and end-to-end compensation in WSON (2009)

We experimentally investigate impairment aware routing and end-to-end compensation in a WSON testbed. The extended control plane modules for QoT optimization and two compensation control strategies are realized and verified in terms of optical power adaptive adjustment.
Radioembolization of Liver Metastases From Colorectal Cancer Using Yttrium-90 Microspheres With Concomitant Systemic Oxaliplatin, Fluorouracil, and Leucovorin Chemotherapy (2007)

The maximum-tolerated dose was 60 mg/m2 of oxaliplatin for the first three cycles, with full FOLFOX4 doses thereafter. This chemoradiation regime merits evaluation in phase II-III trials.
Low-Power 2.4-GHz Transceiver With Passive RX Front-End and 400-mV Supply (2006)

An ultra low power 2.4-GHz transceiver targeting wireless sensor network applications is presented. The receiver front-end is fully passive, utilizing an integrated resonant matching network to achieve voltage gain and interface directly to a passive mixer. The receiver achieves a 7-dB noise figure and -7.5-dBm IIP3 while consuming 330 muW from a 400-mV supply. The binary FSK transmitter delivers 300 muW to a balanced 50-Omega load with 30% overall efficiency and 45% power amplifier (PA) efficiency. Performance of the receiver topology is analyzed and simple expressions for the gain and noise figure of both the passive mixer and matching network are derived. An analysis of passive mixer input impedance reveals the potential to reject interferers at the mixer input with characteristics similar to an extremely high-Q parallel LC filter centered at the switching frequency