gebhart/patrepeval huggingface dataset:
Synthesis of prostaglandin H2 methyl ester (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of prostaglandin H2 methyl esterRoy A. Johnson, Eldon G. Nidy, Lubomir Baczynskyj, and Robert R. GormanCite this: J. Am. Chem. Soc. 1977, 99, 23, 7738–7740Publication Date (Print):November 1, 1977Publication History Published online1 May 2002Published inissue 1 November 1977https://pubs.acs.org/doi/10.1021/ja00465a071https://doi.org/10.1021/ja00465a071research-articleACS PublicationsRequest reuse permissionsArticle Views73Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Monodisperse porous nanodiscs with fluorescent and crystalline wall structure (2010)

We report a facile solution process to synthesize monodisperse porous nanodiscs through confined molecular self-assembly of surfactants and ZnTPyP. The nanodiscs exhibit trimodal pores with fluorescent and crystalline wall structures, and are potentially important for sorption and separation, sensors, catalytic materials, electrode materials, etc.
Design of inter-administrative domain routing protocols (1990)

Policy Routing (PR) is a new area of development that attempts to incorporate policy related constraints on inter-Administrative Domain (AD) communication into the route computation and forwarding of inter-AD packets.
Model-Based Control of HCCI Engines Using Exhaust Recompression (2009)

Homogeneous charge compression ignition (HCCI) is one of the most promising piston-engine concepts for the future, providing significantly improved efficiency and emissions characteristics relative to current technologies. This paper presents a framework for controlling an HCCI engine with exhaust recompression and direct injection of fuel into the cylinder. A physical model is used to describe the HCCI process, with the model states being closely linked to the thermodynamic state of the cylinder constituents. Separability between the effects of the control inputs on the desired outputs provides an opportunity to develop a simple linear control scheme, where the fuel is used to control the work output and the valve timings are used to control the phasing of combustion. The controller is tested on both a single and multi-cylinder HCCI engine, demonstrating the value of a physical model-based control approach that allows an easy porting of the control structure from one engine to another. Experimental results show good tracking of both the work output and combustion phasing over a wide operating region on both engines. In addition, the controller is able to balance out differences between cylinders on the multi-cylinder engine testbed, and reduce the cycle-to-cycle variability of combustion.
CsPbBr<sub>3</sub> QD/AlO<sub><i>x</i></sub> Inorganic Nanocomposites with Exceptional Stability in Water, Light, and Heat (2017)

Abstract Herein, the assembly of CsPbBr 3 QD/AlO x inorganic nanocomposites, by using atomic layer deposition (ALD) for the growth of the amorphous alumina matrix (AlO x ), is described as a novel protection scheme for such QDs. The nucleation and growth of AlO x on the QD surface was thoroughly investigated by miscellaneous techniques, which highlighted the importance of the interaction between the ALD precursors and the QD surface to uniformly coat the QDs while preserving the optoelectronic properties. These nanocomposites show exceptional stability towards exposure to air (for at least 45 days), irradiation under simulated solar spectrum conditions (for at least 8 h), and heat (up to 200 °C in air), and finally upon immersion in water. This method was extended to the assembly of CsPbBr x I 3− x QD/AlO x and CsPbI 3 QD/AlO x nanocomposites, which were more stable than the pristine QD films.
Structure-activity relationship of a series of nitrogen mustard- and pyrrole-containing minor groove-binding agents related to distamycin. (1994)

Two series of tethered nitrogen mustards based on the minor groove-binding and A/T sequence-specific natural product distamycin have been synthesized and evaluated. The conjugates, which have a modified dimethylamino C-terminus, are comprised of one, two or three pyrrole carboxamide units linked to either benzoic acid mustard (BAM) or chlorambucil (CHL). The DNA binding properties, in vitro cytotoxicities and DNA cross-linking abilities were determined for each of the conjugates. The conjugates were found to bind preferentially to poly(dA.dT) compared to poly(dG.dC) DNA by ethidium displacement and circular dichroism. The di- and tripyrrole conjugates had higher binding affinities than the monopyrrole conjugates. All the conjugates were more cytotoxic than the nitrogen mustards themselves. Cytotoxicity increased with the increase from one to three pyrrole units and the CHL conjugates were more cytotoxic than the corresponding BAM analogues. The CHL conjugates were able to cross-link plasmid DNA at a 10-fold lower dose than CHL itself. The BAM conjugates showed < 10% cross-linking at doses which gave 100% cross-linking with the CHL conjugates. In cells, the CHL conjugates showed significant cross-linking at the IC50 values, while the BAM conjugates showed no evidence of cross-link formation even at 10 times the IC50 value. These results are discussed in reference to a series of previously reported GC-recognizing imidazole analogues possessing the same nitrogen mustard groups.
Analog placement with symmetry and other placement constraints (2006)

In order to handle device matching in analog circuits, some pairs of modules are required to be placed symmetrically. This paper addresses this device-level placement problem for analog circuits and our approach can handle symmetry constraint and other placement constraints simultaneously. The problem of placing devices with symmetry constraint has been extensively studied but none of the previous works has considered symmetry constraint with other placement constraints simultaneously. Instead of handling the constraints by having a penalty term in the cost function to penalize violations, a unified method is proposed that, by adjusting the edge weights in a pair of constraint graphs, can try to satisfy all the placement and symmetry constraints simultaneously in a candidate floorplan solution. The maximum distance of the modules in a symmetry group from the corresponding symmetry axis will be minimized in this weight adjusting step, in order to minimize the total packing area. We have compared our method with the most updated results on this problem [2] when there are only symmetry constraints and results show that our approach can give solutions of better quality, in an acceptable amount of run time. We will also demonstrate the effectiveness of our approach in handling different types of constraints simultaneously by testing on data sets with both symmetry and other placement constraints, and the results are very promising.
Getting Access to the "Underground"--Insights into Children's Identities Online (2004)

Increasingly computers in primary schools are being used to support the interactions and learning of students online. Gaining access to online spaces gives students new ways of interacting, not possible in a face-to-face setting. For example, interacting through online environments allows students to interact more informally with each other and with other participants than is generally permitted in the classroom. In this paper we examine the ways students in a grade 5/6 class interacted with each other and the researcher/teacher using a guest book, email account and a chatroom on a class web site and later, using Messenger. The paper examines the informal online interactions of the students and how these inter actions impacted on the student and teacher/student inter actions in the classroom. Students appropriated online names and used the anonymity of the Internet to their adantage. The study concludes with a set of recommendations for the use of interacte technologies in the primary school classroom.
Human Tissues: Chemical Composition and Photon Dosimetry Data (1974)

Chemical compositions of bone (femur), bone (rib), brain (whole), spinal cord, heart (whole, auricles, right and left ventricles), kidney, liver, lungs, muscle, ovaries, pancreas, spleen, and tongue are given for an average human adult. Photon mass attenuation coefficient μ and mass energy absorption coefficient $\mu _{{\rm en}}$ for these tissues are given for photon energies ranging from 15 KeV to 2 MeV.
[Molecular cloning of rat OB gene and its expression in Escherichia coli]. (1999)

In order to provide rat OB gene product for studying the relationship between obesity and noninfectious diseases, rat OB cDNA was amplified by RT-PCR technique. 460 bp fragment of OB cDNA was subcloned into EcoRI/BamHI site of plasmid pUC 19. Sequence analysis of OB cDNA revealed that the translation reading frame was identical with that reported in the literature. Thereby plasmid pBV220-rOB was constructed and the specific expression of OB gene in E. coli identified by SDS-PAGE electrophoresis was obtained.
Building appliances out of components using Pebble (2000)

Appliances are special purpose systems that offer high processing speed, ease of configuration, safety, fault isolation, and minimal need for administration by human experts. Traditional approaches to building an appliance operating system have been either building it from scratch [CacheOS] or stripping down a monolithic kernel to its basic components [Jaeger99]. The former approach is costly and the resulting product is likely to be highly specialized and not easily extensible. The latter approach is not easy, as the OS code and data structures are often shared and closely intertwined. The resulting OS is also likely to be coarse-grained and not easily customizable. Most appliances are network-centric (e.g. HTTP caches, proxies, file servers, routers) in the sense that they require high-performance network connections. Such performance is often achieved with application-specific specialization of system I/O [Cao95] requiring a modification of a portion of the operating system, such as the protocol stack or the file system.Safety is a major concern for appliances, since new functions are constantly added, and there is never enough time to debug all possible interactions, especially when third party software is running on the appliance. The problem is more severe with legacy software written in C or other unsafe languages (in contrast with type-safe languages such as Java). Extensible routers are an example of network appliances where custom software processing has to be quickly added and safety is paramount. Diagnostic code and custom (e.g. multimedia) schedulers are also examples of extensions that appliances will need to support.Resource management is especially important for appliances. New operating system abstractions such as paths [Mosberger96], resource containers [Banga99], reservation domains [Bruno98] and activities [Jones95] have been proposed for resource management and control. We believe that an appliance operating system should be flexible enough to support such abstractions. It should also be able to overlay resource management in modular operating systems without such support.Pebble [Gabber99] is a component-based operating system that combines efficient IPC with strong modularity and safety features. Pebble provides the necessary infrastructure for building fine-grained, modular operating systems for appliances out of reusable components. We found that a typical network appliance application (e.g. a Web server) built on Pebble using components has comparable performance to a traditional monolithic kernel. In this way, there is no performance reason not to use a safer, more modular component structure for such appliances. Moreover, we claim that Pebble is a general purpose operating system framework that allows us to implement diverse OS structures and mechanisms, alleviating the need for writing specialized operating systems from scratch.
Quantitative forward mutation assay in Salmonella typhimurium using 8-azaguanine resistance as a genetic marker. (1978)

We have developed a quantitative forward mutation assay using Salmonella typhimurium, in which resistance to the purine analog 8-azaguanine is used as a genetic marker. We present the assay protocol, the concentration-dependent toxicity and mutagenicity of five known mutagens (N-methyl-N'-nitro-N-nitrosoguanidine, ICR-191, 9-aminoacridine, dimethylnitrosamine, and benzo[a]pyrene), and reconstruction experiments testing the assay for possible bias. The relative merits of forward versus reverse mutation assays are discussed.
Improvement in mammography interpretation skills in a community radiology practice after dedicated teaching courses: 2-year medical audit of 38,633 cases. (1992)

The authors conducted a complete audit of results of 38,633 mammographic examinations performed by 12 general radiologists during a 2-year period with a computerized reporting system. During this period, 11 group members attended 17 dedicated mammography courses. Audit results were analyzed for each radiologist and the entire group. In the 2nd year, the number of breast cancers diagnosed increased 50% (from 121 to 181), with a 6.5% increase in patient volume. Sensitivity increased from 80% to 87%, and there was no change in the positive predictive value of 32%. Median tumor size and node positivity decreased. Most major variables of population and technical factors were unchanged. Diagnostic approach was altered during the 2nd year, as shown by a 50% increase in the use of spot compression, magnification views, and sonography. Analysis of each radiologist's performance before and after attending mammography courses showed similar changes. These data suggest that dedicated mammography courses can help improve radiologists' performance and alter their interpretive approach.
Issues related to reduced cost and increased productivity in acquisition, processing, and integration of 3-D seismic data (1995)

Industry reports indicate that approximately 75–85% of the cost of implementing 3-D seismic data as an exploration or field development process can be attributed to the acquisition survey, be it land or marine. The remaining 15–25% of the cost is generally attributed to data processing, interpretation, and integration of the data volume into a reservoir model. These percentages do vary but the point remains in order to significantly reduce 3-D seismic costs, more attention must be given to acquisition methods and field operations.
A systematic review of the dark side of CRM: the need for a new research agenda (2020)

Technology provides businesses with the opportunity to better engage with customers, but the speed and scope of transformation in customer management have triggered a dark side, affecting people, companies and societies. Research is needed to structure and manage the dark side concept more systematically, considering aspects of dark side behaviours in relation to customer relationship management. Marketers frequently cite research on surveillance, cyber resilience, the dark web, theft by customers/staff, the illicit monetisation of data to third parties, and many other topics as examples of the dark side. The paper reviews the current state of the research and practice regarding the dark side of CRM and explores the dimensions and consequences. A conceptual framework is devised, which captures four important drivers of the dark side – namely unfairness, distrust, opportunism and lack of transparency. The theoretical and managerial implications are discussed.
Service Identification: BPM and SOA Handshake (2007)

Service identification is one of the first steps in the Service Oriented Development life cycle. This has been challenging to application development teams for several reasons, such as lack of business process documentation or perspective, reuse analysis expertise, and lack of business executive involvement coupled with turbulence in the project teams. This article emphasizes the need to do value-chain analysis – in depth business process analysis coupled with use case analysis across multiple projects identified in enterprise SOA initiative. This article mentions some best practices, wherever appropriate, to point out the vagueness involved in service identification.
Automatic Detection System for Cough Sounds as a Symptom of Abnormal Health Condition (2009)

The problem of attending to the health of the aged who live alone has became an important issue in developed countries. One way of solving the problem is to check their health condition by a remote-monitoring technique and support them with well-timed treatment. The purpose of this study is to develop an automatic system that can monitor a health condition in real time using acoustical information and detect an abnormal symptom. In this study, cough sound was chosen as a representative acoustical symptom of abnormal health conditions. For the development of the system distinguishing a cough sound from other environmental sounds, a hybrid model was proposed that consists of an artificial neural network (ANN) model and a hidden Markov model (HMM). The ANN model used energy cepstral coefficients obtained by filter banks based on human auditory characteristics as input parameters representing a spectral feature of a sound signal. Subsequently, an output of this ANN model and a filtered envelope of the signal were used for making an input sequence for the HMM that deals with the temporal variation of the sound signal. Compared with the conventional HMM using Mel-frequency cepstral coefficients, the proposed hybrid model improved recognition rates on low SNR from 5 dB down to -10 dB. Finally, a preliminary prototype of the automatic detection system was simply illustrated.
A Display System for Surgical Navigation in ORL Surgery (2000)

Minimally invasive surgery, developed during the last 15 years becomes a major field of surgical intervention. The patient benefits from little damage around the focus of surgery. Special skills of the surgeon are needed to work in narrow body cavities with little space for the endoscope and surgical tools.
BARD1: An independent predictor of survival in non‐small cell lung cancer (2011)

BRCA1 mRNA overexpression is correlated with poor survival in NSCLC. However, BRCA1 functions depend on the interaction with BARD1 for its stability, nuclear localization and ubiquitin ligase activity. Expression of alternatively spliced BARD1 isoforms that lack the BRCA1-interaction domain was found upregulated and correlated with poor prognosis in breast and ovarian cancer. These BARD1 isoforms are essential for proliferation of cancer cells in vitro. We investigated whether BARD1 isoforms are expressed in NSCLC. While in lung tissues from healthy controls BARD1 expression was undetectable on the mRNA level and protein level, we found two novel isoforms in addition to previously identified mRNAs expressed in all NSCLC samples tested. Furthermore, the pattern of BARD1 isoform expression was similar in tumor and morphologically normal peri-tumor tissues, and only one novel isoform π was specifically upregulated in tumors. Immunohistochemistry revealed that all 100 NSCLC cases tested expressed isoform-specific BARD1 epitopes, while BARD1 expression was undetectable in biopsies from healthy controls. Statistical analysis showed that the expression of epitopes PVC and WFS, present on isoform π, or epitope WFS alone, expressed on isoforms π, κ and β, were significantly correlated with decreased patient survival. These findings were corroborated in a mouse model of chemically induced lung cancer. Immunostaining of mouse tumors showed that BARD1 epitopes PVC and WFS were specifically upregulated in invasive, but not in confined lung tumors. Thus, BARD1 isoforms might be involved in tumor initiation and invasive progression and might represent a novel prognostic marker for NSCLC.
Le Regime des Baies et des Golfes en Droit International. By Jean Mochot. (Paris: Nizet et Bastard, 1938. pp. vi, 191.) (1938)

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Idiom recognition in the Polaris parallelizing compiler (1995)

Article Free Access Share on Idiom recognition in the Polaris parallelizing compiler Authors: Bill Pottenger Center for Supercomputing Research and Development, University of Illinois at Urbana-Champaign, 1308 West Main Street, Urbana, Illinois Center for Supercomputing Research and Development, University of Illinois at Urbana-Champaign, 1308 West Main Street, Urbana, IllinoisView Profile , Rudolf Eigenmann Center for Supercomputing Research and Development, University of Illinois at Urbana-Champaign, 1308 West Main Street, Urbana, Illinois Center for Supercomputing Research and Development, University of Illinois at Urbana-Champaign, 1308 West Main Street, Urbana, IllinoisView Profile Authors Info & Claims ICS '95: Proceedings of the 9th international conference on SupercomputingJuly 1995 Pages 444–448https://doi.org/10.1145/224538.224655Online:03 July 1995Publication History 69citation339DownloadsMetricsTotal Citations69Total Downloads339Last 12 Months14Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF