gebhart/patrepeval huggingface dataset:
The effects of chance and romantic motives on consumer preferences (2018)

My dissertation advances our understandings about how chance and romantic motives influence consumer behavior. The first essay examines why chance events are often perceived more favorably and how such events impact the consumer experience. A series of studies demonstrate that consumers come to infer a stronger link between a chance event and their own self-concept. This increased self-product connection occurs as a means to restore a sense of control over chance events. This effect occurs regardless of limited mental resources, suggesting that the proposed effect is not due to increased elaboration during chance encounters. Consistent with the conceptualization, this effect is attenuated when control is restored, when the product has a negative valence, and when consumers are led to focus on others and not the self. This research is the first to examine the hidden factors that lead chance to become associated with good fortune. The second essay considers whether romantic pair-bond motivations influence numerical preferences. Across cultures and throughout history, the number “2” has been symbolic of a romantic pair bond. I propose that reminders of romance should lead people to prefer the number “2” and associated even numbers. A series of studies demonstrate that romantic motives – goals related to forming a romantic pair-bond – increase preference for the number “2” and other numbers of its parity (i.e., even vs. odd numbers) and marketing stimuli featuring even (vs. odd) numbers. This effect is specific to romantic motives and does not occur for other relationship motives such as those related to work relationship, kinship, and friendship. Consistent with a motivational perspective, the desire to form a romantic relationship statistically mediated the effect of romantic cues on preference for even numbers. Subsequently, the effect of romantic motives on preference for even numbers is suppressed when mating goals are easy to achieve or a committed romantic pair-bond (with one partner) is not important. Across two essays, my dissertation provides novel insight into the hidden influences of chance and romantic motives on the consumer experience. This work has important implications for consumers, marketers, and researchers. Namely, the conceptual underpinning advanced in both essays provides a richer understanding of two unknown, persistent biases in consumer behavior. Insights from this work can help consumers and marketers design optimal decision environments to enhance enjoyment and find work-arounds for biases in preferences, as well as advance future research.
weedNet: Dense Semantic Weed Classification Using Multispectral Images and MAV for Smart Farming (2017)

Selective weed treatment is a critical step in autonomous crop management as related to crop health and yield. However, a key challenge is reliable and accurate weed detection to minimize damage to surrounding plants. In this letter, we present an approach for dense semantic weed classification with multispectral images collected by a micro aerial vehicle (MAV). We use the recently developed encoder-decoder cascaded convolutional neural network, SegNet, that infers dense semantic classes while allowing any number of input image channels and class balancing with our sugar beet and weed datasets. To obtain training datasets, we established an experimental field with varying herbicide levels resulting in field plots containing only either crop or weed, enabling us to use the normalized difference vegetation index as a distinguishable feature for automatic ground truth generation. We train six models with different numbers of input channels and condition (fine tune) it to achieve ~0.8 F1-score and 0.78 area under the curve classification metrics. For the model deployment, an embedded Graphics Processing Unit (GPU) system (Jetson TX2) is tested for MAV integration. Dataset used in this letter is released to support the community and future work.
A Review of the Diagnosis and Treatment of Rosacea (2010)

Rosacea is a common chronic inflammatory disease of the skin and is associated with a number of etiological causes and inciting factors. It is characterized by erythematous changes of the facial skin, and commonly presents with papules, pustules, or telangiectasias. The 4 subtypes of rosacea are categorized according to secondary symptoms, such as pain, erythema, dryness, and edema. A number of therapies are available to treat rosacea, some of which can be used in combination. The mainstays of therapy are topical metronidazole, topical azelaic acid, and oral tetracyclines. Other pharmacotherapeutic interventions have been shown to improve the signs and symptoms of rosacea, although many of these have not yet received approval by the US Food and Drug Administration for this indication.
Effect of rifampin and itraconazole on the pharmacokinetics of zanubrutinib (a Bruton's tyrosine kinase inhibitor) in Asian and non-Asian healthy subjects (2019)

These results confirm that zanubrutinib is primarily metabolized by CYP3A in humans. The PK of zanubrutinib was comparable between Asian and non-Asian subjects and, therefore, no dose modifications are necessary for zanubrutinib in these ethnic populations.
Immunoblotting and culture positive endocarditis. (1991)

Serum samples from patients with endocarditis due to Streptococcus mutans, Streptococcus pneumoniae, Streptococcus agalactiae, Streptococcus lactis and a "nutritionally" variant streptococcus were immunoblotted against antigenic extracts from all five species. In S mutans endocarditis there was an endocarditis specific pattern of IgM against bands of 220, 200, and 190 kilodaltons. In S pneumoniae IgM against antibody of a molecular weight greater than 150 kilodaltons was specific to endocarditis. In S agalactiae IgM against bands at 82, 71, and 66-67 kilodaltons was endocarditis specific. In S lactis endocarditis specific IgM was present against antigenic bands at 105, 66, 61 and 58 kilodaltons. With the "nutritionally" variant streptococcus it was impossible to distinguish between cases of endocarditis and controls.
<i>In Vitro</i>and<i>in Vivo</i>Analysis of the Regulation of a Transcription Factor Gene by Thyroid Hormone during<i>Xenopus laevis</i>Metamorphosis (1999)

A novel, basic region leucine zipper transcription factor (TH/bZIP) is dramatically up-regulated at the climax of metamorphosis in Xenopus laevis. It can be induced in tadpoles prematurely by thyroid hormone (TH) with kinetics that are intermediate between early and late Xenopus TH response genes. A small amount of early, cycloheximide-resistant up-regulation is observed, but the majority of TH/ bZIP mRNA accumulation occurs after 12 h of treatment in parallel with late response gene induction. There are two genomic TH/bZIP genes in the pseudotetraploid X. laevis genome that are coordinately regulated. They have highly conserved regulatory regions that contain two conserved, adjoining DR+4 thyroid response elements (TRE) in opposite orientation. The early/late TH induction kinetics has been reproduced in transient transfection assays. The secondary rise of transcriptional activity requires DNA regions other than the TREs and, therefore, the interaction of transcription factors other than the TH receptors. Finally, the regulatory region of the TH/bZIP gene has been used to drive green fluorescent protein in transgenic X. laevis tadpoles. Regulation of the transgene during spontaneous and induced metamorphosis mimics that of the endogenous TH/bZIP gene. The newly developed X. laevis transgenesis method has distinct advantages for the analysis of transcriptional regulatory elements over transient transfection assays and will be useful for further in vivo studies of TH-response gene regulation during development.
Insights into Atomic-Level Interaction between Mefenamic Acid and Eudragit EPO in a Supersaturated Solution by High-Resolution Magic-Angle Spinning NMR Spectroscopy (2013)

The intermolecular interaction between mefenamic acid (MFA), a poorly water-soluble nonsteroidal anti-inflammatory drug, and Eudragit EPO (EPO), a water-soluble polymer, is investigated in their supersaturated solution using high-resolution magic-angle spinning (HRMAS) nuclear magnetic resonance (NMR) spectroscopy. The stable supersaturated solution with a high MFA concentration of 3.0 mg/mL is prepared by dispersing the amorphous solid dispersion into a d-acetate buffer at pH 5.5 and 37 °C. By virtue of MAS at 2.7 kHz, the extremely broad and unresolved (1)H resonances of MFA in one-dimensional (1)H NMR spectrum of the supersaturated solution are well-resolved, thus enabling the complete assignment of MFA (1)H resonances in the aqueous solution. Two-dimensional (2D) (1)H/(1)H nuclear Overhauser effect spectroscopy (NOESY) and radio frequency-driven recoupling (RFDR) under MAS conditions reveal the interaction of MFA with EPO in the supersaturated solution at an atomic level. The strong cross-correlations observed in the 2D (1)H/(1)H NMR spectra indicate a hydrophobic interaction between the aromatic group of MFA and the backbone of EPO. Furthermore, the aminoalkyl group in the side chain of EPO forms a hydrophilic interaction, which can be either electrostatic or hydrogen bonding, with the carboxyl group of MFA. We believe these hydrophobic and hydrophilic interactions between MFA and EPO molecules play a key role in the formation of this extremely stable supersaturated solution. In addition, 2D (1)H/(1)H RFDR demonstrates that the molecular MFA-EPO interaction is quite flexible and dynamic.
The melt hollow fiber spinning process: steady‐state behavior, sensitivity and stability (1994)

Abstract The rheology of the melt hollow fiber spinning process is examined in the thin filament limit. The resulting thin filament equations are also applicable to single‐phase and two‐phase extensional flows. Using a novel numerical solution procedure, the sensitivity of the fiber spinning equations to material property and process variations is investigated. Fiber geometry is directly controlled by the mass flowrates of the core and clad fluids while the spinline tension is most strongly influenced by clad viscosity. A maximum can occur in the clad stress profile if a core liquid is used and the ratio of core to clad viscosity increases greatly with temperature. Isothermal spinning of high viscosity clad liquids with either a core gas or liquid is unstable for draw ratios greater than 20.2 as found for solid fibers.
Aortic dissection: a 250-year perspective. (2011)

Two hundred fifty years have passed since Frank Nicholls' history-making, accurate observations on the anatomic findings and cause of death of King George II were published. Several decades later, the disease was named, using--for the first time--the terms dissection and dissecting attached to an aortic disease process. Another century went by before effective surgical treatment was developed. In sharp contrast, the evolution of the last 20 years has been nothing short of amazing. Our understanding of AD, while not yet complete, has improved dramatically. In addition, the introduction of nonsurgical endovascular therapy has had a profoundly transformative impact--and we are just at the beginning! It would not be unreasonable to predict that stent-graft repair will likely replace (or nearly replace) open surgery in the treatment of complicated type B dissection in the near future, especially as technologies continue to improve and indication-specific designs are developed and tested in the clinical setting. Moreover, it is predictable that endovascular solutions for some patients with type A aortic dissection will become available in the years to come as surgical results continue to be suboptimal. Finally, and amidst this plethora of “good news,” it is appropriate to reflect on the formidable challenge that endovascular therapies face as they gear to “compete” with optimal medical therapy in the management of patients with acute uncomplicated type B dissection, because it will obviously be difficult (if not impossible) to improve on the already-achieved 30-day mortality rate of less than 10%. Long-term gains may well become the winning card when and if the late results of TEVAR can be shown to improve on the rather compromised outlook of medically treated dissection patients. Stay tuned.
Hooked! Modeling human disease in zebrafish (2012)

Zebrafish have been widely used as a model system for studying developmental processes, but in the last decade, they have also emerged as a valuable system for modeling human disease. The development and function of zebrafish organs are strikingly similar to those of humans, and the ease of creating mutant or transgenic fish has facilitated the generation of disease models. Here, we highlight the use of zebrafish for defining disease pathways and for discovering new therapies.
Evaluation of maskless electron beam direct writing with double character projection apertures (2010)

In this paper, we propose and evaluate maskless electron beam direct writing (EBDW) with double character projection (CP) apertures. In the conventional CP-capable EBDW, the first aperture generates a square beam and the second aperture finalizes the complex character shape. In our proposed method, each aperture has complex character patterns. The double CP apertures system projects circuit patterns onto a wafer by the combined use of two apertures. We present a novel pattern writing algorithm for double CP apertures, especially a generation/merging method of character patterns. The experimental results on ITC'99 benchmark circuit b19 synthesized with Nangate 45nm Open Cell Library showed that throughput of the proposed method was enhanced up to 147.3% of the variable-shaped beam method and up to 117.5% of the conventional CP method.
Adaptive Nonlinear Finite Elements for Deformable Body Simulation Using Dynamic Progressive Meshes (2001)

Realistic behavior of deformable objects is essential for many applications such as simulation for surgical training. Existing techniques of deformable modeling for real time simulation have either used approximate methods that are not physically accurate or linear methods that do not produce reasonable global behavior. Nonlinear finite element methods (FEM) are globally accurate, but conventional FEM is not real time. In this paper, we apply nonlinear FEM using mass lumping to produce a diagonal mass matrix that allows real time computation. Adaptive meshing is necessary to provide sufficient detail where required while minimizing unnecessary computation. We propose a scheme for mesh adaptation based on an extension of the progressive mesh concept, which we call dynamic progressive meshes.
Effects of Jaw Clenching While Wearing a Customized Bite-Aligning Mouthpiece on Strength in Healthy Young Men (2015)

Recent studies have investigated the ergogenic effects of different types of mouthguards. There is evidence of the benefits of clenching customized mouthpieces on force and power development. The phenomenon called concurrent activation potentiation (CAP) promoted in jaw clenching seems to enhance the muscular strength and power in maximal isometric contractions and powerful actions in sport. Moreover, a bite-aligning mouthpiece may promote a more aligned and powerful clench. The objective of the present study was to investigate the effects of jaw clenching while wearing a customized bite-aligning mouthpiece (MP) on jump ability and isometric maximal strength tests in contrast to 2 other conditions: nonjaw clenching (NON-JAW) and jaw clenching without the mouthpiece (JAW). A within-subjects design was used to assess the jump performance and the maximal isometric force in 28 physically active male subjects. Statistical analyses revealed significantly higher performance in JAW and NON-JAW conditions for handgrip force (HG-peakforce) and all variables of the back-row exercise (BRW) and countermovement vertical jump (CMVJ) (p ≤ 0.05). Significant differences between NON-JAW and JAW were found for HG-peakforce (p ≤ 0.05). These findings suggest that it is advisable to use a customized bite-aligning mouthpiece to improve strength and power performance.
Water and Biodiversity (2013)

Banko Janakari, Vol. 23, No. 1, Page 1-2 DOI: http://dx.doi.org/10.3126/banko.v23i1.9461
High-speed photonically assisted analog-to-digital conversion using a continuous wave multiwavelength source and phase modulation (2008)

A more simple photonically assisted analog-to-digital conversion system utilizing a cw multiwavelength source and phase modulation instead of a mode-locked laser is presented. The output of the cw multiwavelength source is launched into a dispersive device (such as a single-mode fiber). This fiber creates a pulse train, where the central wavelength of each pulse corresponds to a spectral line of the optical source. The pulses can then be either dispersed again to perform discrete wavelength time stretching or demultiplexed for continuous time analog-to-digital conversion. We experimentally demonstrate the operation of both time stretched and interleaved systems at 38 GHz. The potential of integrating this type of system on a monolithic chip is discussed.
Acceptability of Vaginal Film, Soft-Gel Capsule, and Tablet as Potential Microbicide Delivery Methods Among African Women (2011)

All three dosage forms were acceptable to the women surveyed. Preferred dosage forms varied by country. These data suggest that the availability of microbicides in multiple dosage forms may increase acceptability, adherence, and, therefore, effectiveness.
Macroscale and microscale organic experiments (1989)

The market leader for the full-year organic laboratory, this manual derives many experiments and procedures from the classic Feiser lab text, giving it an unsurpassed reputation for solid, authoritative content. The book includes new experiments that stress greener chemistry, updated NMR spectra, and a Premium Website that includes glassware-specific videos with pre-lab exercises. Offering a flexible mix of macroscale and microscale options for most experiments, this proven manual allows users to save on the purchase and disposal of expensive, sometimes hazardous organic chemicals. Macroscale versions can be used for less costly experiments, giving readers experience working with conventionally sized glassware.
Influence of Stress on Distribution of Endotoxin in RES Determined by Fluorescein Antibody Technic. (1957)

Summary1. Deposition of endotoxin of Salmonella typhosawas followed in normal and stressed rabbits by the fluorescein tagging technic. 2. Pretreatment with cortisone and x-irradiation did not affect initial phagocytosis of toxin but inhibited degradation and elimination of toxin by the RES. 3. Pretreatment with thorotrast and preliminary injection of toxin caused depression of initial phagocytic functioning of the RES to a subsequent injection of toxin. 4. Our findings in their possible relation to the generalized Shwartzman reaction were discussed.
Oat β‐glucan increases postprandial cholecystokinin levels, decreases insulin response and extends subjective satiety in overweight subjects (2009)

This study recorded acute biochemical and subjective measures of satiety, followed by energy intake from a subsequent meal, after varying doses of beta-glucan in extruded breakfast cereals. Molecular weight, solubility and viscosity of beta-glucan products were determined. Seven male and seven female subjects (BMI 25-36 kg/m) consumed five breakfasts (different doses of beta-glucan sourced from two different technological processes) and dietary intake was measured after four hours. Blood was collected to measure glucose, insulin, ghrelin and cholecystokinin, and visual analogue scales measured subjective satiety. Molecular weight, solubility and viscosity indicated products were likely to increase luminal viscosity. beta-Glucan was found to decrease insulin secretion over 2 h (RMANOVA, p = 0.011) in a dose responsive manner from 2.16 to 5.68 g per serving (p = 0.007). Cholecystokinin levels increased linearly over the same range of beta-glucan concentrations (p = 0.002) in women. Subjective satiety was increased at a beta-glucan dose of 2.2 g (p = 0.039). Subsequent meal intake decreased by greater than 400 kJ with higher beta-glucan dose (>5 g). beta-Glucan improves satiety and release of cholecystokinin is likely to be part of the mechanism. Products with different sources of beta-glucan provide similar benefits but each product requires individual testing.
Backbone Dynamics of Cyclotide MCoTI‐I Free and Complexed with Trypsin (2010)

Showing some backbone: Most of the backbone NH groups of cyclotide MCoTI-I are constrained in the free state, which results in a well-folded compact structure, as indicated by {15N,1H} NMR spectroscopy (see picture). According to the backbone order parameter S2, the backbone mobility in trypsin-bound MCoTI-I is significantly increased.
Granulocyte Collection by Continuous-flow Filtration Leukapheresis (1972)

Abstract A safe and simple technique for the collection of large numbers of granulocytes from normal donors, based on the reversible adhesion of granulocytes to nylon wool filters, is described. The procedure is well tolerated by donors, and the granulocytes obtained show nearly normal bactericidal and phagocytic capacity in vitro. However, a surprisingly small median 1-hr posttransfusion increment of 233/cu mm was observed in leukopenic recipients lacking preformed leukocyte antibodies, as compared to the median increment of 850/cu mm reported following transfusion of leukocytes obtained by differential centrifugation. The safety and effectiveness of these granulocytes for the treatment or prevention of bacterial infections in granulocytopenic patients remains to be proven, however our initial experience with such transfusions has been encouraging.
Picosecond Pulse Sequential Waveform Generation (2005)

This paper describes a novel method of generating a pulse sequence using step-recovery diodes shunting a transmission line. Individual pulses in the train may have risetimes less than 60 ps with amplitudes greater than 10 V. The many potential applications of the device include a short RF pulse generator, an FM generator, and a high-speed word generator.
The actions of retinoids on cellular growth correlate with their actions on gap junctional communication. (1989)

Retinoic acid (a possible morphogen), its biological precursor retinol, and certain synthetic derivatives of retinol profoundly change junctional intercellular communication and growth (saturation density) in 10T 1/2 and 3T3 cells and in their transformed counterparts. The changes correlate: growth decreases as the steady-state junctional permeability rises, and growth increases as that permeability falls. Retinoic acid and retinol exert quite different steady-state actions on communication at noncytotoxic concentrations in the normal cells: retinoic acid inhibits communication at 10(-10)-10(-9) M and enhances at 10(-9)-10(-7) M, whereas retinol only enhances (10(-8)-10(-6) M). In v-mos-transformed cells the enhancement is altogether lacking. But regardless of the retinoid or cell type, all growth responses show essentially the same dependence on junctional permeability. This is the expected behavior if the cell-to-cell channels of gap junctions disseminate growth-regulating signals through cell populations.