gebhart/patrepeval huggingface dataset:
Sensitive Glass Microfibre‐Based Histamine Analysis for Allergy Testing in Washed Blood Cells (1985)

The new microfibre method for allergy testing is based on basophil histamine release after challenge with suspected allergens in samples of 50 microliter washed blood cells. Released histamine is bound to microfibres and measured after removal of interfering substances by washing. The microfibre method was compared with the conventional leukocyte histamine release assay in 18 allergic patients tested with 10 different allergens. It was found that the same individuals responded with histamine release to the same allergens in both assays, and the number of responders was almost identical. Also the dose-response curves and the cell sensitivity were almost identical, which further substantiated identity between the results obtained by the new microfibre method and the conventional assay. A comparison between the microfibre method and in vivo provocation tests showed good agreement when comparing the number of positive and negative responses in these test. The new method overcomes the problems in allergy testing, where only small amounts of blood are available and many tests have to be carried out.
Tut Rare Sound Events, Development Dataset (2017)

TUT Rare Sound events 2017, development dataset consists of source files for creating mixtures of rare sound events (classes baby cry, gun shot, glass break) with background audio, as well a set of readily generated mixtures and recipes for generating them. The "source" part of the dataset consists of two subsets: background recordings from 15 different acoustic scenes, recordings with the target rare sound events from three classes, accompanied by annotations of their temporal occurrences, a set of meta files providing the cross-validation setup: lists of background and target event recordings split into training and test subsets (called "devtrain" and "devtest", respectively, indicating they are provided as the development dataset, as opposed to the evaluation dataset released separately). The mixture set consists of two subsets (training and testing), each containing ~1500 mixtures (~500 per target class in each subset, with half of the mixtures not containing any target class events). The collection of the background recording data has been financially supported by European Research Council under the European Unions H2020 Framework Programme through ERC Grant Agreement 637422 EVERYSOUND.
Cure kinetics of bismaleimides as basis for polyimide‐like inks for PolyJet™‐3D‐printing (2018)

ABSTRACT Since polyimides are well known for their excellent chemical and thermal stability and outstanding mechanical properties there is increasing interest in developing polyimide‐based inks to produce additively manufactured parts with properties superior to those of currently available materials. Usage of bismaleimides (BMI) as precursors allows polyimides to be fabricated via PolyJet™ printing (Stratasys Ltd., Rehovot, Israel). Characterization of the curing kinetics is a central part of process development, as fast curing initiated by UV light is desired. Here, a comprehensive study of thermal and UV curing of BMI oligomers with various molecular weights and chemical structures is presented. Fourier transform infrared spectroscopy serves as a tool for determining the curing degree. Furthermore, an estimation of the activation energy for thermal curing is performed. UV curing of the selected BMIs leads to highly crosslinked, thermoset polymers with excellent chemical resistance and thermal stability which are of great interest for PolyJet™ 3D printing. © 2018 The Authors. Journal of Applied Polymer Science published by Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019 , 136 , 47244.
ChemInform Abstract: Reduction of Surface Stacking Faults on N‐Type (100)Silicon Wafers. (1986)

Abstract It is shown that the reason that n‐type (l00)Si wafers usually form stacking faults rather than S‐ pits after a 1100°C steam oxidation in the presence of metal contamination is that their surfaces can more easily be contaminated with metals compared to other wafer types and orientations.
<i>TP53</i>Mutations in Breast and Ovarian Cancer (2016)

Breast and ovarian cancers are the second and fifth leading causes of cancer deaths among women. Both breast and ovarian cancers are highly heterogeneous and are presented with diverse morphology, natural history, and response to therapy. In recent years, international efforts have led to extensive molecular characterization of both breast and ovarian tumors and identified biologically and clinically relevant subtypes of the diseases based on these molecular features. The role of TP53 in tumor initiation and progression is context dependent, and abrogation of the TP53 pathway seems to be essential for the development of basal-like breast cancers and high-grade serous ovarian cancers. These subtypes of breast and ovarian cancer show several genomic similarities including high frequency of TP53 mutation, which seems to be an early, initiating, and driving alteration in these cancer subtypes.
Endomorphins in rheumatoid arthritis, osteoarthritis, and experimental arthritis (2010)

The opioid tetrapeptides endomorphins (EM)-1 and EM-2 are widely expressed in central nervous system and immune tissues of rats and humans. Their analgesic properties are well characterized but they also have anti-inflammatory properties. EM-1 significantly attenuated the onset of hindpaw inflammation in adjuvant-induced arthritis in rats. Immunohistochemical staining demonstrated the presence of EMs in T cells, macrophages, and fibroblasts in synovial tissues from patients with osteo- or rheumatoid arthritis (RA). In an ex vivo superfusion system, EM-1 potently inhibited the release of proinflammatory cytokines interleukin (IL)-6 and IL-8 from synovial tissues from patients with osteo- or RA. These results demonstrate that EMs are endogenously synthesized within human immune cells and have the potential to act as potent therapeutic agents in the treatment of chronic inflammatory disease. We discuss the clinical potential for EM analogues chemically modified to resist proteolytic degradation and identify modified protease-resistant analogues with enhanced bioactivity.
Molecular cloning, gene structure and expression profile of mouse C1 inhibitor (1998)

The gene encoding C1 inhibitor, the major control element of activation of the classical pathway of complement and a major inhibitor of several plasma serine proteases, has been studied only in man, where deficiency of C1 inhibitor results in the dominantly transmitted disease hereditary angioedema. Full-length mouse C1 inhibitor cDNA and genomic clones were isolated and characterized as a first step towards the complete characterization of the pattern of C1 inhibitor expression and the production of an animal model of C1 inhibitor deficiency. Restriction-enzyme and sequence analyses of a full-length genomic clone demonstrated that the mouse gene has the same structure as the human homologue, but differs in size (9 kb versus 17 kb), mostly due to the presence of repetitive Alu elements in the human gene. Sequence comparisons in the promoter region indicate important similarities, i.e. the absence of a TATA box, the presence of an initiator sequence encompassing the transcription-start site and of a gamma-interferon-activated sequence (GAS) element at position -124 of the human sequence. A stretch of about 100 nucleotides in intron 1 reveals an unusually high degree of conservation for non-coding sequences and contains non-canonical but conserved tandemly arranged GAS elements at positions 369 and 388 of the human sequence. This finding supports the conclusions of functional studies on the human C1INH gene indicating a role of this region in modulation of transcription by interferons. The profile of C1 inhibitor expression in mouse liver, lung, heart, kidney, spleen and brain was determined by quantitative northern blot analysis.
Non-Profiled Deep Learning-based Side-Channel attacks with Sensitivity Analysis (2019)

Deep Learning has recently been introduced as a new alternative to perform Side-Channel analysis [MPP16]. Until now, studies have been focused on applying Deep Learning techniques to perform Profiled Side-Channel attacks where an attacker has a full control of a profiling device and is able to collect a large amount of traces for different key values in order to characterize the device leakage prior to the attack. In this paper we introduce a new method to apply Deep Learning techniques in a Non-Profiled context, where an attacker can only collect a limited number of side-channel traces for a fixed unknown key value from a closed device. We show that by combining key guesses with observations of Deep Learning metrics, it is possible to recover information about the secret key. The main interest of this method is that it is possible to use the power of Deep Learning and Neural Networks in a Non-Profiled scenario. We show that it is possible to exploit the translation-invariance property of Convolutional Neural Networks [CDP17] against de-synchronized traces also during Non-Profiled side-channel attacks. In this case, we show that this method can outperform classic Non-Profiled attacks such as Correlation Power Analysis. We also highlight that it is possible to break masked implementations in black-box, without leakages combination pre-preprocessing and with no assumptions nor knowledge about the masking implementation. To carry the attack, we introduce metrics based on Sensitivity Analysis that can reveal both the secret key value as well as points of interest, such as leakages and masks locations in the traces. The results of our experiments demonstrate the interests of this new method and show that this attack can be performed in practice.
Detecting tapping motion on the side of mobile devices by probabilistically combining hand postures (2014)

We contribute a novel method for detecting finger taps on the different sides of a smartphone, using the built-in motion sensors of the device. In particular, we discuss new features and algorithms that infer side taps by probabilistically combining estimates of tap location and the hand pose--the hand holding the device. Based on a dataset collected from 9 participants, our method achieved 97.3% precision and 98.4% recall on tap event detection against ambient motion. For detecting single-tap locations, our method outperformed an approach that uses inferred hand postures deterministically by 3% and an approach that does not use hand posture inference by 17%. For inferring the location of two consecutive side taps from the same direction, our method outperformed the two baseline approaches by 6% and 17% respectively. We discuss our insights into designing the detection algorithm and the implication on side tap-based interaction behaviors.
Cyclin-Dependent Kinase 5 Regulates PSD-95 Ubiquitination in Neurons (2011)

Cyclin-dependent kinase 5 (Cdk5) and its activator p35 have been implicated in drug addiction, neurodegenerative diseases such as Alzheimer's, learning and memory, and synapse maturation and plasticity. However, the molecular mechanisms by which Cdk5 regulates synaptic plasticity are still unclear. PSD-95 is a major postsynaptic scaffolding protein of glutamatergic synapses that regulates synaptic strength and plasticity. PSD-95 is ubiquitinated by the ubiquitin E3 ligase Mdm2, and rapid and transient PSD-95 ubiquitination has been implicated in NMDA receptor-induced AMPA receptor endocytosis. Here we demonstrate that genetic or pharmacological reduction of Cdk5 activity increases the interaction of Mdm2 with PSD-95 and enhances PSD-95 ubiquitination without affecting PSD-95 protein levels in vivo in mice, suggesting a nonproteolytic function of ubiquitinated PSD-95 at synapses. We show that PSD-95 ubiquitination correlates with increased interaction with β-adaptin, a subunit of the clathrin adaptor protein complex AP-2. This interaction is increased by genetic reduction of Cdk5 activity or NMDA receptor stimulation and is dependent on Mdm2. Together these results support a function for Cdk5 in regulating PSD-95 ubiquitination and its interaction with AP-2 and suggest a mechanism by which PSD-95 may regulate NMDA receptor-induced AMPA receptor endocytosis.
Multi user MIMO‐OFDM‐based power line communication structure with hardware impairments and crosstalk (2017)

Broadband power line communication (BPLC) provides high speed data services without requiring the installation of new infrastructure. Multiple‐input–multiple‐output orthogonal frequency division multiplexing (MIMO‐OFDM) technology can significantly improve the BPLC performance. In this study a new multi‐user (MU) MIMO‐OFDM structure for BPLC is proposed. The effects of physical hardware impairments on the performance of this structure are also presented. Unlike to MIMO‐BPLC with ideal hardware, the hardware impairments cause a capacity limit at high signal‐to‐noise ratio (SNR). Another technical challenge in designing MIMO BPLC network is the crosstalk between MIMO PLC ports which has non‐negligible effect on network capacity. In order to reduce the effects of crosstalk, the authors propose a new scheme based on applying Pre‐coding at the transmitter before applying the singular value decomposition (SVD) on the MIMO channel. Due to the nature of the power‐line channel, the different users have different channel conditions. Thus this study also addresses the application of an efficient resource allocation algorithm to improve the overall performance of the proposed BPLC structure. The obtained results indicate that by applying the proposed resource allocation algorithm along with the Maximum Ratio Combining Pre‐coding (Pre‐MRC), the proposed structure becomes insensitive to crosstalk and has significant channel capacity compared to conventional PLC networks.
Skeletal muscle aging (2007)

Average world life expectancy has seen a dramatic rise over the last two centuries although active life expectancy remains relatively unchanged. One reason for this is that aging results in skeletal muscle becoming smaller, weaker and more susceptible to contraction-induced injury. By the age of 70, muscle strength is reduced by around 30–40% and this can have catastrophic effects on quality of life. Despite a vast amount of research into age-related changes in skeletal muscle, the exact mechanisms responsible for this is still unclear and thus treatments to preserve muscle function with aging remain elusive.
Tissue-Specific Microdissection Coupled with ProteinChip <sup>®</sup> Array Technologies: Applications in Cancer Research (2000)

Analysis of whole genomes to monitor specific changes in gene activation or changes in gene copy number due to perturbation has recently become possible using DNA chip technologies. It is now becoming apparent, however, that knowing the genetic sequence encoding a protein is not sufficient to predict the size or biological nature of a protein. This can be particularly important in cancer research where posttranslational modifications of a protein can specifically lead to the disease. To address this area, several proteomic tools have been developed. Currently the most widely used proteomics tool is two-dimensional polyacrylamide gel electrophoresis (2D-PAGE), which can display protein expression patterns to a high degree of resolution. However, 2D-PAGE can be time consuming; the analysis is complicated and, compared with DNA techniques, is not very sensitive. Although some of these problems can be alleviated by using high-quality homogeneous samples, such as those generated using microdissection techniques, the quantity of sample is often limited and may take several days to generate sufficient material for a single 2D-PAGE analysis. As an alternative to 2D-PAGE, a preliminary study using a new technique was used to generate protein expression patterns from either whole tissue extracts or microdissected material. Surface-enhanced laser desorption and ionization allows the retention of proteins on a solid-phase chromatographic surface or ProteinChip Array with direct detection of retained proteins by time-of-flight mass spectrometry. Using this system, we analyzed tumor and normal tissue from head and neck cancer and microdissected melanoma to determine differentially expressed proteins. In particular, comparisons of the protein expression patterns from microdissected normal and tumor tissues indicated several differences, highlighting the importance of extremely defined tissue lysates for protein profiling.
Effect of Salt Stress on Seed Germination and Seedling Growth of Three Salinity Plants (2008)

Seeds of three halophyte species included Limonium sinense Kuntze, Glycine soja sieb. and Sorghum sudanense Stapf. were used to investigate the effects of different salinity concentrations on their germination percentage, germination energy, germination index, relative germination rate, relative salt-injury rate, radicle length and hypocotyl length. Results showed that seeds of G. soja can germinate well and rapidly at lower level of salt (< 200 mmol L(-1)), 50 mmol L(-1) salt concentrations is better to S. sudanense, suitable salt concentrations was beneficial to germinate of S. sudanense seeds. Seeds of L. sinense and S. sudanense can germinate at higher level of salt (400 mmol L(-1)). Three plant seeds had different physiological mechanism for germination under salt stress, radicle hypocotyl ratio of L. sinense and S. sudanense increased with increasing salt suggested that they had the higher tolerance in shoot growth under NaCl stress, which is perhaps the reason for their wide utilisation for saline soil rehabilitation.
Sound navigation aid system for the vision impaired (2012)

Visually impaired or blind people are someone who lost their ability to see. They usually depend on guide cane or guide dog to assist them navigates their environment. However, guide cane requires the blind to scan the surrounding manually with their hand while guide dog is expensive and has a short life span. There are many researches on creating better navigation aid for blind people. Instead of using vibration or alarm to notify the distance of the obstacles, this research proposed the application of sound notification for the blind. This system is developed using MATLAB r2010a with the integrated webcam of the laptop and a laser pointer. The laser pointer acts as a reference point so that object's distance can be calculated from the captured image by the webcam. This system manages to calculate distance for any color of object under any level of brightness condition during day and night time. It also possesses human head movement ability to turn left and right, up and down. This system managed to detect the obstacles up to a distance of 432 centimeters, which is sufficient to prevent the blind from bumping into the obstacles. The calculated distance is then converted to sound in order to notify the blind how far the object is away from them.
False-Positive Western Blot Tests for Antibodies to HTLV-IIIN (1986)

<h3>To the Editor.—</h3> As part of the US Army quality assurance program for human T-cell lymphotropic virus type III (HTLV-III) testing, we recently sent identical proficiency panels to five large commercial firms that offered HTLV-III Western blot testing on a fee-for-service basis. Each panel consisted of 15 samples from healthy, low-risk adults whose serum was repeatedly negative for HTLV-III antibodies and five samples from HTLVIII-infected (culture-documented) patients. By Western blot analysis, all five positive samples produced definite, but not strong, bands at 41 kilodaltons (kd) and other molecular weights characteristic of HTLV-III proteins.<sup>1</sup> Scores ranged from 85% to 100% accuracy (Table). Four of the five laboratories reported at least one falsepositive test result. The six falsepositive results were all on different normal specimens, suggesting that the errors were due to technique and not to intrinsic biologic properties of the specimens. There was a substantial range of clarity of the
Value-Added Processing of Peanut Meal: Aflatoxin Sequestration during Protein Extraction (2010)

The efficacy of a bentonite clay, Astra-Ben 20A (AB20A), to sequester aflatoxin from contaminated (approximately 110 ppb) peanut meal during protein extraction was studied. Aqueous peanut meal dispersions (10% w/w) were prepared by varying the pH, temperature, enzymatic hydrolysis conditions, and concentrations of AB20A. After extraction, dispersions were centrifuged and filtered to separate both the water-soluble and the water-insoluble fractions for subsequent testing. Inclusion of AB20A at 0.2 and 2% reduced (p < 0.05) aflatoxin concentrations below 20 ppb in both fractions; however, the higher concentration of AB20A also reduced (p < 0.05) the water-soluble protein content. Inclusion of 0.2% AB20A did not affect protein solubility, total soluble solids, or degree of hydrolysis. Peanut meal adsorption isotherms measured the AB20A capacity to sequester aflatoxin. These results are discussed in the context of a process designed to sequester aflatoxin from contaminated peanut meal, which could enable derivatives of this high protein material to be utilized in enhanced feed and/or food applications.
Low-PAPR Polarization-Time Code with Improved Four-Dimensional Detection for PDL Mitigation (2020)

We apply a polarization-time pre-coding together with an improved four-dimensional (4D) detection for polarization dependent loss mitigation. By taking advantage of the correlation between the noises, the proposed scheme outperforms state-of-the-art PDL mitigation methods.
Results of <sup>89</sup> Strontium Therapy in Patients with Carcinoma of the Prostate and Incurable Pain from Bone Metastases: A Preliminary Report (1976)

The therapeutic application of 89strontium for the relief of pain in 11 cases of carcinoma of the prostate with skeletal metastases is reported. A significant clinical improvement could be observed in 8 of the 11 patients with generalized osseous metastases of prostatic carcinoma after the application of 30 muCi. 89strontium per kg. The effect was long lasting. At the same time an increase of alkaline phosphatase was observed, which was interpreted as an indication of the reactivation of osteoblasts and osteoid peripheral zones owing to beta-emission of the radioisotope in the affected areas. The indications for such therapy are discussed.
Water Treatment Using Discharge Generated in Cavitation Field with Micro Bubble Cloud (2013)

SUMMARY A new method of wastewater treatment using electric discharge in the water cavitation field formed by a large number of micro bubbles generated by high‐speed water flow is proposed in this paper. Indigo carmine solution, which is a type of dye, with a concentration of 9 mg/liter was used as the specimen solution for demonstration of water treatment. The total volume of solution and the average speed of solution in the cavitation field were 20 liters and about 7.4 m/s, respectively. An absorbance decrease rate of 96% was obtained in 50 min of treatment time at the electrode distance of 2 mm and discharge power of 16 W. It was also found that the efficiency of decolorization was improved by changing the electrode location. © 2013 Wiley Periodicals, Inc. Electr Eng Jpn, 186(4): 1–10, 2014; Published online in Wiley Online Library ( wileyonlinelibrary.com ). DOI 10.1002/eej.22483