gebhart/patrepeval huggingface dataset:
Improving Factor-Based Quantitative Investing by Forecasting Company Fundamentals (2017)

On a periodic basis, publicly traded companies are required to report fundamentals: financial data such as revenue, operating income, debt, among others. These data points provide some insight into the financial health of a company. Academic research has identified some factors, i.e. computed features of the reported data, that are known through retrospective analysis to outperform the market average. Two popular factors are the book value normalized by market capitalization (book-to-market) and the operating income normalized by the enterprise value (EBIT/EV). In this paper: we first show through simulation that if we could (clairvoyantly) select stocks using factors calculated on future fundamentals (via oracle), then our portfolios would far outperform a standard factor approach. Motivated by this analysis, we train deep neural networks to forecast future fundamentals based on a trailing 5-years window. Quantitative analysis demonstrates a significant improvement in MSE over a naive strategy. Moreover, in retrospective analysis using an industry-grade stock portfolio simulator (backtester), we show an improvement in compounded annual return to 17.1% (MLP) vs 14.4% for a standard factor model.
Sexually Acquired Vascular Injuries of the Penis: A Review (2000)

Lee, Jacky BS; Singh, Baljeet MD; Kravets, Felix G. BS; Trocchia, Aron BS; Waltzer, Wayne C. MD; Khan, S. Ali MD, FRCS Author Information
<i>In situ</i> formation of palisade bodies in calcium, aluminum‐rich refractory inclusions (1997)

Abstract— It has been suggested that palisade bodies—shells of spinel found within some calcium, aluminum‐rich inclusions (CAIs) and the phases the shells enclose—are intact mini‐CAIs that predate and were captured by their current hosts while the latter were still molten. We present new data and observations that indicate that most palisade bodies formed instead in situ while their host inclusions were crystallizing. The evidence includes observations of spinel‐lined cavities and glass‐filled, circular structures outlined by spinel in experimental run products crystallized from melts; a partially formed palisade body in an inclusion; a fassaite crystal that is optically continuous across a palisade wall; and similarity of unusual mineral compositions in some palisade bodies and their hosts. Our observations can be used to refute arguments for exotic origin and are most consistent with a model for in situ formation involving: (1) formation of vesicles in a largely molten inclusion; (2) nucleation of spinel upon and/or adherence to vapor‐melt interfaces, forming spinel shells around vesicles; (3)leakage of vesicles and filling with melt while spinel shells remain largely intact; and (4) crystallization of melt inside shells. This model is similar to one proposed for formation of segregation vesicles, which are partially‐ to completely‐filled vesicles found in some terrestrial basalts. In addition, we interpret framboids ( i.e. , dense clusters of spinel with little material between grains, found in most inclusions that contain palisade bodies) as polar or near‐polar sections through palisade bodies and therefore do not make a genetic distinction between the two features.
A photoelectrochemical investigation of the n- and p-type semiconducting behaviour of copper(I) oxide films (1989)

Copper(I) oxide films were prepared on copper substrates by exposing them to solutions containing Cu2+ ions, and it was observed that the photoresponse of these films electrodes in a photoelectrochemical cell is both n- and p-type. However, it was observed that the n-type behaviour of these film electrodes could be enhanced and the p-type behaviour could be reduced by adjusting the pH of the solution in which the oxide films had been prepared. The simultaneous existence of spatially separated n- and p-type regions in the Cu2O film is suggested as the possible reason for these observations. The anodic oxidation of copper was considered to be the origin of the p-type regions while the n-type regions were considered to be the result of the cathodic deposition of Cu2O.
Dopamine-Mediated Volume Transmission in Midbrain Is Regulated by Distinct Extracellular Geometry and Uptake (2001)

Somatodendritic release of dopamine (DA) in midbrain is, at least in part, nonsynaptic; moreover, midbrain DA receptors are predominantly extrasynaptic. Thus somatodendritic DA mediates volume transmission, with an efficacy regulated by the diffusion and uptake characteristics of the local extracellular microenvironment. Here, we quantitatively evaluated diffusion and uptake in substantia nigra pars compacta (SNc) and reticulata (SNr), ventral tegmental area (VTA), and cerebral cortex in guinea pig brain slices. The geometric parameters that govern diffusion, extracellular volume fraction (alpha) and tortuosity (lambda), together with linear uptake (k'), were determined for tetramethylammonium (TMA(+)), and for DA, using point-source diffusion combined with ion-selective and carbon-fiber microelectrodes. TMA(+)-diffusion measurements revealed a large alpha of 30% in SNc, SNr, and VTA, which was significantly higher than the 22% in cortex. Values for lambda and k' for TMA(+) were similar among regions. Point-source DA-diffusion curves fitted theory well with linear uptake, with significantly higher values of k' for DA in SNc and VTA (0.08--0.09 s(-1)) than in SNr (0.006 s(-1)), where DA processes are sparser. Inhibition of DA uptake by GBR-12909 caused a greater decrease in k' in SNc than in VTA. In addition, DA uptake was slightly decreased by the norepinephrine transport inhibitor, desipramine in both regions, although this was statistically significant only in VTA. We used these data to model the radius of influence of DA in midbrain. Simulated release from a 20-vesicle point source produced DA concentrations sufficient for receptor activation up to 20 microm away with a DA half-life at this distance of several hundred milliseconds. Most importantly, this model showed that diffusion rather than uptake was the most important determinant of DA time course in midbrain, which contrasts strikingly with the striatum where uptake dominates. The issues considered here, while specific for DA in midbrain, illustrate fundamental biophysical properties relevant for all extracellular communication.
EFFECT OF IONIC CROSSLINKING ON DENSITY OF HYDROGEL CHITOSAN MEMBRANES (2013)

Ionically crosslinked chitosan membranes were prepared and their density was determined using modified pycnometer method. High‑molecular compound: sodium alginate (NaAlg) and low‑molecular compounds: pentasodium tripolyphosphate (TPP) and trisodium citrate (CIT) were used as ionic crosslinkers of chitosan. As a reference liquid n‑heptane solution was chosen. It was found out that density of modified chitosan membranes is strongly affected by the type of ionic crosslinker and membrane preparation conditions.
New Solar Water-Splitting Reactor With Ferrite Particles in an Internally Circulating Fluidized Bed (2009)

The thermal reduction of metal oxides as part of a thermochemical two-step water-splitting cycle requires the development of a high-temperature solar reactor operating at 1000–1500°C. Direct solar energy absorption by metal-oxide particles provides direct efficient heat transfer to the reaction site. This paper describes the experimental results of a windowed small reactor using an internally circulating fluidized bed of reacting metal-oxide particles under direct solar-simulated Xe-beam irradiation. Concentrated Xe-beam irradiation directly heats the internally circulating fluidized bed of metal-oxide particles. NiFe2O4∕m‐ZrO2 (Ni-ferrite on zirconia support) particles are loaded as the working redox material and are thermally reduced by concentrated Xe-beam irradiation. In a separate step, the thermally reduced sample is oxidized back to Ni-ferrite with steam at 1000°C. The conversion efficiency of ferrite reached 44% (±1.0%), which was achieved using the reactor at 1kW of incident Xe lamp power. The effects of preheating temperature and NiFe2O4∕m‐ZrO2 particle size on the performance of the reactor for thermal reduction using an internally circulating fluidized bed were evaluated.
A Generic Approach to Functionalizing Aromatic Polyimides for Second-Order Nonlinear Optics (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Generic Approach to Functionalizing Aromatic Polyimides for Second-Order Nonlinear OpticsDong Yu, Ali Gharavi, and Luping YuCite this: Macromolecules 1995, 28, 3, 784–786Publication Date (Print):January 1, 1995Publication History Published online1 May 2002Published inissue 1 January 1995https://pubs.acs.org/doi/10.1021/ma00107a017https://doi.org/10.1021/ma00107a017research-articleACS PublicationsRequest reuse permissionsArticle Views240Altmetric-Citations70LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Laboratory evaluation of insecticides and biopesticides against Phenococcus solenopsis and Paracoccus marginatus infesting cotton (2010)

Acephate 700g a.i. /ha, Chlorpyriphos 500g a.i./ha, NSKE 5%, Neem oil (2.5 l /ha) + Nirma powder (0.1%), Nirma powder 0.1 %, Verticillium lecanii 5gm/lit (2 x 10 8 cfu/gm), Beauveria bassiana 5gm/lit (2 x 10 8 cfu/gm), Metarhizium anisopliae 5gm/lit (2 x 10 8 cfu/gm), Bacterial symbiont of entomopathogenic nematode (Photorhabdus luminescens) 20ml/lit (2 x 10 8 cfu/ml), Fish oil rosin soap 2ml / lit., Mealy Quit (New botanical formulation from CICR, Nagpur) 100ml/lit and Control (Water alone) were tested against nymphs and adults of Phenacoccus solenopsis and Paracoccus marginatus using cotton leaves (Bunny Bt) dipped in respective treatment solutions and air dried to remove excess water. Observations on insect mortality were recorded at 24 and 48h after treatment. Among different treatment tested on P. solenopsis nymphs, acephate recorded the highest mortality of 53.3 % at 48h after treatment. All the biopesticides tested were found to be on par in causing mortality of nymphs and adults. Chlorpyriphos and Mealy Quit were equally toxic causing 48.9% mortality at 48h after treatment. When tested against adults, the same trend of results was observed. When these treatments were tested against P. marginatus nymphs, again acephate ranked first with 55.56 % mortality at 48h after treatment. Chlorpyriphos, Mealy Quit and Fish Oil rosin soap were equally toxic causing 51.1 to 52.2 % mortality at 48h after treatment. Further studies are in progress to test the results under field condition.
Structural control of rubber modified thermoplastic as produced by the mass process (1974)

Abstract Commercially important polyblends can be produced by a mass process which proceeds via the dispersion of a rubber solution phase. During the process several distinct stages can be identified and structural variation of the final polymer is achieved by controlled agitation. The relationship between the nature and structure of the dispersed phase and the mechanical properties of the polyblend are illustrated and discussed in the light of current theories of impact enhancement.
MALDI-TOF Mass Spectrometry Compatible Inactivation Method for Highly Pathogenic Microbial Cells and Spores (2008)

Identification of microorganisms, specifically of vegetative cells and spores, by intact cell mass spectrometry (ICMS) is an emerging new technology. The technique provides specific biomarker profiles which can be employed for bacterial identification at the genus, species, or even at the subspecies level holding the potential to serve as a rapid and sensitive identification technique in clinical or food microbiology and also for sensitive detection of biosafety level (BSL) 3 microorganisms. However, the development of ICMS as an identification technique for BSL-3 level microorganisms is hampered by the fact that no MALDI-TOF (matrix-assisted laser desorption/ionization time-of-flight) compatible inactivation procedure for microorganisms, and particularly for bacterial endospores, has been evaluated so far. In this report we describe a new methodology for effective inactivation of microorganisms which is compatible with the analysis of microbial protein patterns by MALDI-TOF mass spectrometry. The main challenge of this work was to define the conditions that ensure microbial inactivation and permit at the same time comprehensive analysis of microbial protein patterns. Among several physical, chemical, and mechanical inactivation procedures, inactivation by trifluoroacetic acid (TFA) proved to be the best method in terms of bactericidal capacity and information content of the mass spectra. Treatment of vegetative cells by 80% TFA alone for 30 min assured complete inactivation of microbial cells under all conditions tested. For spore inactivation, the "TFA inactivation protocol" was developed which is a combination of TFA treatment with basic laboratory routines such as centrifugation and filtering. This MALDI-TOF/ICMS compatible sample preparation protocol is simple and rapid (30 min) and assures reliable inactivation of vegetative cells and spores of highly pathogenic (BSL-3) microorganisms.
기녀시조의 감성특성과 시조사 (2000)

The purpose of this paper is to analyze, from a historical perspective, the characteristics of poetic sensitiveness embedded in the Sijo (時調) poems...
Arrayed identification of DNA signatures (2006)

Over the last few years, several initiatives have described efforts to combine previously invented techniques in molecular biology with parallel detection principles to sequence or genotype DNA signatures. The Infinium system from Illumina and the Affymetrix GeneChips are two systems suitable for whole-genome scoring of variable positions. However, directed candidate-gene approaches are more cost effective and several academic groups and the private sector provide techniques with moderate typing throughput combined with large sample capacity suiting these needs. Recently, whole-genome sequencing platforms based on the sequencing-by-synthesis principle were presented by 454 Life Sciences and Solexa, showing great potential as alternatives to conventional genotyping approaches. In addition to these sequencing initiatives, many efforts are pursuing novel ideas to facilitate fast and cost-effective whole genome sequencing, such as ligation-based sequencing. Reliable methods for routine re-sequencing of human genomes as a tool for personalized medicine, however, remain to be developed.
Fusion to a homo-oligomeric scaffold allows cryo-EM analysis of a small protein (2016)

Recent technical advances have revolutionized the field of cryo-electron microscopy (cryo-EM). However, most monomeric proteins remain too small (<100 kDa) for cryo-EM analysis. To overcome this limitation, we explored a strategy whereby a monomeric target protein is genetically fused to a homo-oligomeric scaffold protein and the junction optimized to allow the target to adopt the scaffold symmetry, thereby generating a chimeric particle suitable for cryo-EM. To demonstrate the concept, we fused maltose-binding protein (MBP), a 40 kDa monomer, to glutamine synthetase, a dodecamer formed by two hexameric rings. Chimeric constructs with different junction lengths were screened by biophysical analysis and negative-stain EM. The optimal construct yielded a cryo-EM reconstruction that revealed the MBP structure at sub-nanometre resolution. These findings illustrate the feasibility of using homo-oligomeric scaffolds to enable cryo-EM analysis of monomeric proteins, paving the way for applying this strategy to challenging structures resistant to crystallographic and NMR analysis.
Finite-Element Bending Analysis for Plates (1967)

A general approximate solution method applicable to the bending analysis of structural plates is presented. The plates may have variable thicknesses and arbitrary shapes. Additionally, the plates may possess variable material properties. Arbitrary normal, thermal and boundary loading conditions have been included. The analysis has been so formulated that it may be easily adapted to the analysis of folded plate and shell structures. The analysis is developed by expressing the plate bending equations, written as functions of the transverse deflection, and the bending moments, by means of a variational theorem. The plate to be analyzed is represented by a series of finite elements. Forms of the primary dependent variables (transverse deflection and moments) are assumed within each element and are related to moment and displacement unknowns at the element nodes. The approximate solution is obtained by taking the variational of the function with respect to the node values of the unknowns, thus generating a set of linear algebraic equations which define these nodal values. The application and accuracy of the procedure is illustrated by an example.
Synergy of ciprofloxacin with fosfomycin <i>in vitro</i> against <i>Pseudomonas</i> isolates from patients with cystic fibrosis (1988)

Pseudomonas aeruginosa remains the most common respiratory pathogen causing morbidity and mortality in cystic fibrosis (CF) patients. The in-vitro activity of ciprofloxacin and fosfomycin (calcium and tromethamine salts) in combination against P. aeruginosa isolates from CF patients, all of whom had received previous courses of ciprofloxacin, was evaluated by agar plate dilution chequerboard technique. The concentrations of drugs used were those that would be achieved in patients by oral and intravenous (fosfomycin only) routes. Synergy, taking into account fosfomycin concentrations achievable intravenously, was found against 60% of P. aeruginosa isolates. With concentrations achieved after an oral dose, 17% of isolates were synergistically inhibited. Time-kill experiments confirmed these findings. Ciprofloxacin MICs against resistant P. aeruginosa were reduced to achievable sputum and serum levels in the presence of fosfomycin. However, in progressive resistance studies fosfomycin failed to delay the development of resistance to ciprofloxacin. The combinations of ofloxacin/fosfomycin and ciprofloxacin/fosmidomycin were also tested, but showed minimal synergy. No antagonism was observed with any combination. Fosfomycin, ciprofloxacin and azlocillin in triple combination did not show synergy. The antimicrobial combinations tested against P. cepacia isolates from CF patients were indifferent. The combination of ciprofloxacin and fosfomycin may be clinically useful in selected P. aeruginosa pulmonary exacerbations in cystic fibrosis patients, particularly as an oral out-of-hospital treatment alternative or in cases where MICs for ciprofloxacin are elevated.
Reactions of trimethyloxonium fluoroborate with alkylamino- and phenyl-substituted cyclotriphosphonitriles (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of trimethyloxonium fluoroborate with alkylamino- and phenyl-substituted cyclotriphosphonitrilesJohn N. Rapko and Gerald FeistelCite this: Inorg. Chem. 1970, 9, 6, 1401–1405Publication Date (Print):June 1, 1970Publication History Published online1 May 2002Published inissue 1 June 1970https://pubs.acs.org/doi/10.1021/ic50088a022https://doi.org/10.1021/ic50088a022research-articleACS PublicationsRequest reuse permissionsArticle Views156Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
New anion-exchange resins for improved separations of nuclear materials. Mid-year progress report (1997)

'The authors are developing multi-functional anion-exchange resins that facilitate anion uptake by carefully controlling the structure of the anion receptor site. The new ion-exchange resins interface the rapidly developing field of ion-specific chelating ligands with robust, commercial ion exchange technology. The overall objective of the research is to develop a predictive capability which allows the facile design and implementation of multi-functionalized anion exchange materials which selectively sorb metal complexes of interest from targeted process, waste, and environmental streams. The basic scientific issues addressed are actinide complex speciation along with modeling of the metal complex/functional site interactions in order to determine optimal binding-site characteristics. Their approach uses a thorough determination of the chemical species both in solution and as bound to the resin to determine the characteristics of resin active sites which can actively facilitate specific metal-complex sorption to the resin. The first year milestones were designed to allow us to build off of their extensive expertise with plutonium in nitrate solutions prior to investigating other, less familiar systems. While the principle investigators have successfully developed actinide chelators and ion-exchange materials in the past, the authors were fully aware that integration of this two fields would be challenging, rewarding and, at times, highly frustrating. Relatively small differences in the substrate (cross-linkage, impurities), the active sites (percent substitution, physical accessibility), the actinide solution (oxidation state changes, purity) and the analytical procedures (low detection limits) can produce inconsistent sorption behavior which is difficult to interpret. The potential paybacks for success, however, are enormous. They feel that they have learned a great deal about how to control these numerous variables to produce consistent, reliable analysis of actinide sorption behavior with the new and baseline anion-exchange materials. The four Year 1 (FY97) milestones are listed below along with an update on the progress towards their completion.'