gebhart/patrepeval huggingface dataset:
Portable secure identity management for software engineering (2010)

Identity management refers to authentication, sharing of personally identifiable information (PII) and provision of mechanisms protecting the privacy thereof. The most commonly implemented is federated authentication, permitting users to maintain a single set of credentials to access many services. Specifications exist for profile exchange between a service provider (SP) and the identity provider (IdP), but are rarely used. Most frequently, local storage of profile data is utilised due to security and privacy concerns. Key work in this area includes that of the PRIME project, which provides privacy enhancing identity management [1]. Their work utilises local data stores and/or trusted third parties.
Effects of strain on the dielectric properties of tunable dielectric SrTiO3 thin films (2001)

We fabricated an epitaxial Au/SrTiO3(001)/SrRuO3 (or CaRuO3)(001)/SrTiO3 (or LaAlO3)(001) heterostructure to investigate the effect of the strain on the epitaxial tunable dielectric thin films. SrTiO3 thin films showed very different dielectric properties depending on the bottom electrode with an opposite lattice mismatch. The SrTiO3 thin films grown on the CaRuO3 bottom electrodes showed nearly a two times larger tunability than that on SrRuO3. We think this is due to the different strain on the SrTiO3 thin films. The tensile strain along the applied electric field in the parallel plate capacitor enhances the dielectric constant and the tunability, while the compressive strain decreases them. We believe this is consistent with the hardening of the soft mode phonon due to the compressive strain.
Application of Tunable Diode Laser Spectroscopy for Time Resolved Measurements in Electron-Beam Produced Plasma (2007)

Summary form only given. Tunable diode laser absorption spectroscopy was used for the investigation of the temporal evolution of neutral species concentrations in air plasma, which is produced by a 100 keV electron beam at pressures from 760 Torr down to 1 Torr. The spectrometer applied is based on a set of fiber-coupled distributed feedback lasers. Absorption spectra of species (H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O, OH, CO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> , CO, NO and N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O) in near infrared (1.3 -1.8 nm) were recorded with resolution ~ 1 ms. Temperatures and absolute values for the concentrations were found over a broad dynamic range. Possibilities for increasing the signal-to-noise ratio are outlined.
Improved Vision-Related Function After Ranibizumab Treatment of Neovascular Age-Related Macular Degeneration (2007)

clinicaltrials.gov Identifier: NCT00056836.
Semi-automated vertebral segmentation of human spine in MRI images (2016)

Image segmentation is an important task in medical image processing to assist physicians or radiologists in making faster and effective diagnosis and treatment. However, there is still lack of effective segmentation methods to extract human spine in Magnetic resonance imaging (MRI) images. In this study, we propose a segmentation method using 12-anatomical point representation (12-APR) method for human spine vertebra. The proposed method is a semi-automatic segmentation in which 12-points will be manually annotated on the region of interest (ROI) before the ROI can be extracted automatically. The performance of this segmentation is evaluated using six performance metrics and the results show that the proposed method gives the highest accuracy (99.87%), specificity (99.89%), Dice similarity coefficient (94.04%), Jaccard similarity coefficient (88.81%) and Cosine similarity coefficient (94.14%).
Cigarette Smoke‐Induced Oxidative Stress and TGF‐β<sub>1</sub>Increase p21<sup>waf1/cip1</sup>Expression in Alveolar Epithelial Cells (2002)

Sustained oxidative stress caused by cigarette smoking induces a chronic inflammatory response, resulting in the destruction of the alveolar cell wall characteristic of emphysema. The loss of tissue may involve the progressive depletion of epithelial cells through inhibition of proliferation leading to cell death. The cell cycle regulator p21(waf1/cip1) acts as a G(1)/S and G(2)/M phase checkpoint regulator. We hypothesize that cigarette smoke-induced oxidative stress and transforming growth factor beta 1 (TGF-beta(1)) may inhibit cellular proliferation by p21(waf1/cip1) in type II alveolar epithelial cells (A549). A significant increase was observed in p21(waf1/cip1) mRNA expression in A549 cells by cigarette smoke condensate, H(2)O(2), and TGF-beta(1). In conclusion, cigarette smoke-induced oxidative stress and TGF-beta(1) modulate expression of the cell cycle inhibitor p21(waf1/cip1). This may be important in the growth arrest and cell survival of alveolar type II cells in the G(1) phase.
Pulsed High-Intensity Focused Ultrasound Enhances Systemic Administration of Naked DNA in Squamous Cell Carcinoma Model: Initial Experience (2005)

Local exposure to pulsed high-intensity focused ultrasound in tumors can enhance the delivery and expression of systemically injected naked DNA.
Vβ‐Specific Activation of T Cells by the HIV Glycoprotein gp 160 (1995)

Studies by several groups have suggested that HIV infection in vivo results in a V beta-specific alteration of the TCR repertoire and that this might play a role in the pathogenesis of AIDS. However, there is very little agreement as to which V beta segments are affected. In order to circumvent the confounding factors present in vivo we have examined the abilities of both a crude protein extract of HIV and purified gp160 to alter the V beta repertoire of normal T cells in vitro. We find that both a crude extract of HIV as well as gp160 specifically activate T cells expressing a common set of V beta segments (V beta 3, 12, 14, 15, and sometimes V beta 17 and 20) in individuals of disparate HLA type. This set of V beta segments is remarkably similar to those recognized by staphlococcal enterotoxin B and supports the hypothesis that bacterial superantigens produced by opportunistically acquired micro-organisms could have an exacerbating effect in AIDS.
A 50-Gb/s Optical Transmitter Based on Co-design of a 45-nm CMOS SOI Distributed Driver and 90-nm Silicon Photonic Mach-Zehnder Modulator (2020)

This paper presents an integrated optical driver and Mach-Zehnder modulator (MZM) that operates to 50 Gb/ <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$s$</tex> . The MZM consists of 4 traveling wave segments along a 3.2 mm length in a 90-nm Silicon Photonic (SiP) technology. The broadband distributed amplifier is a pseudo-differential design with 3-stack driver stages to deliver sufficient voltage swing in a 45nm CMOS SOI technology. The optical eye is open to 50 Gb/ <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$s$</tex> and indicates error-free operation to 30 Gb/ <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$s$</tex> . The total circuit consumes 480 mW.
A multi-sender asynchronous extension to the AER protocol (2002)

The address-event representation (AER) is an asynchronous point-to-point communications protocol for silicon neural systems. This paper describes an extension of the AER protocol that allows multiple AER senders to share a common bus. A fully-functional silicon implementation of the extended protocol is described, as well as a functional board-level system of several of these chips sharing a common bus.
Effect of recombinant human erythropoietin on the anemia of chronic renal failure (1988)

Phase I and Phase II studies of recombinant human erythropoietin (rhEpo) were conducted in normal volunteers and in anemic patients with chronic renal failure on maintenance hemodialysis. Three hundred U/person of rhEpo was administered intravenously to healthy normal volunteers in the Phase I study, resulting in no subjective or objective changes. In the Phase II study, 66 patients with chronic renal failure on maintenance hemodialysis with less than 20% hematocrit values were treated with rhEpo in doses of 50 U/kg to 200 U/kg two or three times a week. Hematocrit values increased significantly during the 12 weeks, and the patients' conditions improved. Patients previously requiring blood transfusions became transfusion-independent during our study. There were no obvious side effects, thus indicating the safety and efficacy of rhEpo in the anemia of chronic renal failure.
Predominance of <i>Chlamydia trachomatis</i> Serovars Associated with Urogenital Infections in Females in New Delhi, India (2003)

Screening for Chlamydia trachomatis was done for 280 endocervical swab samples by PCR specific for endogenous plasmid. Age dependency was seen in symptomatic patients, with a high chlamydial prevalence rate (28%) found in younger women. Genotyping by restriction fragment length polymorphism analysis of omp1 PCR-positive samples showed serovars D, E, and F to be the most prevalent.
Mechanism of selective methanol oxidation over vanadium oxide-titanium oxide catalysts: a FT-IR and flow reactor study (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMechanism of selective methanol oxidation over vanadium oxide-titanium oxide catalysts: a FT-IR and flow reactor studyGuido. Busca, Ahmed S. Elmi, and Pio. ForzattiCite this: J. Phys. Chem. 1987, 91, 20, 5263–5269Publication Date (Print):September 1, 1987Publication History Published online1 May 2002Published inissue 1 September 1987https://pubs.acs.org/doi/10.1021/j100304a026https://doi.org/10.1021/j100304a026research-articleACS PublicationsRequest reuse permissionsArticle Views1190Altmetric-Citations183LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Cognitive training in older adults with Mild Cognitive Impairment: Impact on cognitive and functional performance (2009)

These results indicate the importance of non-pharmacological interventions for older adults with MCI to help compensate for cognitive decline.
Double-Raman Gain for Realizing a Superluminal Ring Laser (2013)

We show how a dual-peak gain produced via optical pumping and non-degenerate Raman pumps in a single vapor cell can be used to realize a superluminal ring laser with enhanced sensitivity for gyroscopy and accelerometry.
Survey of Procedural Methods for Two-Dimensional Texture Generation (2020)

Textures are the most important element for simulating real-world scenes and providing realistic and immersive sensations in many applications. Procedural textures can simulate a broad variety of surface textures, which is helpful for the design and development of new sensors. Procedural texture generation is the process of creating textures using mathematical models. The input to these models can be a set of parameters, random values generated by noise functions, or existing texture images, which may be further processed or combined to generate new textures. Many methods for procedural texture generation have been proposed, but there has been no comprehensive survey or comparison of them yet. In this paper, we present a review of different procedural texture generation methods, according to the characteristics of the generated textures. We divide the different generation methods into two categories: structured texture and unstructured texture generation methods. Example textures are generated using these methods with varying parameter values. Furthermore, we survey post-processing methods based on the filtering and combination of different generation models. We also present a taxonomy of different models, according to the mathematical functions and texture samples they can produce. Finally, a psychophysical experiment is designed to identify the perceptual features of the example textures. Finally, an analysis of the results illustrates the strengths and weaknesses of these methods.
Focal Cerebral Ischaemia in the Cat: Treatment with the Glutamate Antagonist MK-801 after Induction of Ischaemia (1988)

The effects of the glutamate N-methyl-D-aspartate receptor antagonist MK-801 in reducing ischaemic brain damage have been examined in anaesthetised cats, with drug treatment being initiated 2 h after the induction of cerebral ischaemia. Focal cerebral ischaemia was produced by permanent occlusion of one middle cerebral artery, and the animals were killed 6 h later. The amount of early irreversible ischaemic damage was assessed at 16 predetermined stereotactic planes. Treatment with MK-801 (5 mg/kg, i.v.) 2 h after middle cerebral artery occlusion reduced significantly the volume of ischaemic damage (from 1,625 +/- 384 mm3 of the cerebral hemisphere in vehicle-treated cats to 792 +/- 385 mm3 in MK-801-treated cats). The demonstration of reduced ischaemic brain damage with MK-801, when the agent is administered after the induction of ischaemia, extends the therapeutic potential of such agents in the treatment of focal cerebral ischaemia in humans.
Noncollinear coplanar magneto-optic interaction of guided optical wave and magnetostatic surface waves in yttrium iron garnet-gadolinium gallium garnet waveguides (1985)

Wideband noncollinear coplanar guided-wave magneto-optic diffraction and mode conversion by magnetostatic surface waves at multigigahertz (3–7 GHz) carrier frequencies in yttrium iron garnet-gadolinium gallium garnet waveguides have been observed and measured in detail for the first time. Interaction configuration, physical mechanisms, summary of a theoretical treatment, and some experimental results obtained at 1.152 μm optical wavelength are presented. This noncollinear coplanar magneto-optic interaction configuration should result in a number of integrated optic devices for wideband communications and signal processing applications at electronically tunable microwave carrier frequencies. The potential advantages of the resulting magneto-optic devices over the existing acousto-optic devices are also discussed.
Percutaneous Transvenous Mitral Annuloplasty (2009)

Percutaneous implantation of the PTMA device is feasible and safe. Acute results demonstrate a possibly meaningful reduction of MR in responding patients. Sustained favorable geometric modification of the mitral annulus has been observed, though reduction of MR has been limited. The PTMA method warrants continued evaluation and development.
Interprofessional Perspectives on ABCDE Bundle Implementation (2016)

The number of disciplines required to perform an activity and individual component complexity was reported to influence ABCDE bundle implementation. Nurses repeatedly described challenges with coordinating care across disciplines. Small tests of change, adequate staffing, interprofessional training and protocol development efforts, and role modeling may be effective methods for successful ABCDE bundle implementation.
Going deeper in facial expression recognition using deep neural networks (2016)

Automated Facial Expression Recognition (FER) has remained a challenging and interesting problem in computer vision. Despite efforts made in developing various methods for FER, existing approaches lack generalizability when applied to unseen images or those that are captured in wild setting (i.e. the results are not significant). Most of the existing approaches are based on engineered features (e.g. HOG, LBPH, and Gabor) where the classifier's hyper-parameters are tuned to give best recognition accuracies across a single database, or a small collection of similar databases. This paper proposes a deep neural network architecture to address the FER problem across multiple well-known standard face datasets. Specifically, our network consists of two convolutional layers each followed by max pooling and then four Inception layers. The network is a single component architecture that takes registered facial images as the input and classifies them into either of the six basic or the neutral expressions. We conducted comprehensive experiments on seven publicly available facial expression databases, viz. MultiPIE, MMI, CK+, DISFA, FERA, SFEW, and FER2013. The results of our proposed architecture are comparable to or better than the state-of-the-art methods and better than traditional convolutional neural networks in both accuracy and training time.
Genetic synthesis techniques for low-power digital signal processing circuits (1996)

Power dissipation is becoming a limiting factor in the realisation of VLSI systems. The paper describes two different techniques which employ Genetic Algorithms (GA) for synthesis of digital circuits. The first employs a multi-objective genetic algorithm for structurally synthesising low power circuits. A gate-level description of the circuit is encoded into a single chromosome and the GA evolves by searching for circuit structures that are optimised for both overall capacitive area and critical path. This allows operation under reduced power supply voltages. Although, the technique currently operates at gate-level its main advantages become apparent when used within a high-level framework. Our results are illustrated with examples at the gate-level by using the adder and parity checker problems. The second technique operates on a Data Flow Graph (DFG) consisting of high level blocks such as registers, adders, and multipliers. Operations such as retiming and automatic pipelining are used to reduce the critical path of the DFG, hence allowing operation under reduced supply voltage. Our results are illustrated using an 8th order Avenhaus filter with achievement of more than 50% power saving. (5 pages)
Open-Loop Control of Modular Multilevel Converters Using Estimation of Stored Energy (2011)

The internal control of a modular multilevel converter aims to equalize and stabilize the submodule capacitor voltages independent of the loading conditions. It has been shown that a submodule selection mechanism, included in the modulator, can provide voltage sharing inside the converter arm. Several procedures for controlling the total stored energy in each converter arm exist. A new approach is described in this paper. It is based on estimation of the stored energy in the arms by combining the converter electromotive force reference, the measured alternating output current, and the known direct voltage. No feedback controllers are used. Experimental verification on a three-phase 10 kVA prototype is presented along with the description of the new procedure.
ProfileChaser: searching microarray repositories based on genome-wide patterns of differential expression (2011)

Supplementary data are available at Bioinformatics online.
Genetic instability of plant tissue cultures: breakdown of normal controls. (1994)

Plants regenerated from relatively undifferentiated callus cultures possess a vast array of genetic changes. Such variations can result in useful agricultural and horticultural products. For other purposes, however, variations in traits other than those of interest may be undesirable--for example, using cultured cells for genetic engineering. Any steps made toward understanding the basis of tissue culture-induced genetic variation should be helpful in developing a more stable and manipulatable somatic cell system. This review provides a glimpse at the specific kinds of genetic changes encountered among regenerated plants and their progeny. Included among these variations are cytosine methylation alterations of the genome. The repeat-induced point mutation (RIP) phenomenon, reported for filamentous fungi, is invoked to provide a framework to consider the origin of variation in plant tissue cultures.
The crystal structure of CREG, a secreted glycoprotein involved in cellular growth and differentiation (2005)

The cellular repressor of E1A-stimulated genes (CREG) is a secreted glycoprotein that inhibits proliferation and enhances differentiation of human embryonal carcinoma cells. CREG binds to the cation-independent mannose 6-phosphate (M6P)/insulin-like growth factor II (IGF2) receptor (IGF2R) (M6P/IGF2R), and this receptor has been shown to be required for CREG-induced growth suppression. To better understand CREG function in cellular growth and differentiation, we solved the 3D crystal structure of this protein to 1.9-A resolution. CREG forms a tight homodimeric complex, and CREG monomers display a beta-barrel fold. The three potential glycosylation sites on CREG map to a confined patch opposite the dimer interface. Thus, dimerization of glycosylated CREG likely presents a bivalent ligand for the M6P/IGF2R. Closely related structural homologs of CREG are FMN-binding split-barrel fold proteins that bind flavin mononucleotide. Our structure shows that the putative flavin mononucleotide-binding pocket in CREG is sterically blocked by a loop and several key bulky residues. A mutant of CREG lacking a part of this loop maintained overall structure and dimerization, as well as M6P/IGF2R binding, but lost the growth suppression activity of WT CREG. Thus, analysis of a structure-based mutant of CREG revealed that binding to M6P/IGF2R, while necessary, is not sufficient for CREG-induced growth suppression. These findings indicate that CREG utilizes a known fold for a previously undescribed function [corrected]
GM-CSF contributes to aortic aneurysms resulting from SMAD3 deficiency (2013)

Heterozygous loss-of-function SMAD3 (Mothers against decapentaplegic homolog 3) mutations lead to aneurysm-osteoarthritis syndrome (AOS). In the present study, we found that mice lacking Smad3 had a vascular phenotype similar to AOS, marked by the progressive development of aneurysms. These aneurysms were associated with various pathological changes in transmural inflammatory cell infiltration. Bone marrow transplants from Smad3-/- mice induced aortitis and aortic root dilation in irradiated WT recipient mice. Transplantation of CD4+ T cells from Smad3-/- mice also induced aortitis in Smad3+/+ recipient mice, while depletion of CD4+ T cells in Smad3-/- mice reduced the infiltration of inflammatory cells in the aortic root. Furthermore, IFN-γ deficiency increased, while IL-17 deficiency decreased, disease severity in Smad3+/- mice. Cytokine secretion was measured using a cytokine quantibody array, and Smad3-/- CD4+ T cells secreted more GM-CSF than Smad3+/+ CD4+ T cells. GM-CSF induced CD11b+Gr-1+Ly-6Chi inflammatory monocyte accumulation in the aortic root, but administration of anti-GM-CSF mAb to Smad3-/- mice resulted in significantly less inflammation and dilation in the aortic root. We also identified a missense mutation (c.985A>G) in a family of thoracic aortic aneurysms. Intense inflammatory infiltration and GM-CSF expression was observed in aortas specimens of these patients, suggesting that GM-CSF is potentially involved in the development of AOS.
Nasal Obstruction is the Key Symptom in Hay Fever Patients (2005)

This study provides evidence about the key role played by nasal obstruction in assessing patients with allergic rhinitis.