gebhart/patrepeval huggingface dataset:
Characterization of the mouse histone gene cluster on chromosome 13: 45 histone genes in three patches spread over 1Mb. (1996)

The histone gene cluster on mouse chromosome 13 has been isolated and characterized. Using overlapping YAC clones containing histone genes from chromosome 13, a contig of approximately 2 Mb has been defined. It contains 45 histone genes, organized in three patches containing tightly clustered genes. An 80-kb patch (patch III) containing 12 histone genes is near one end of the contig, and a similar-sized patch (patch I) containing 15 histone genes is near the other end of the contig, located at least 500 kb from the central patch (patch II) of histone genes. The entire cluster contains six histone H1 genes, including the testis-specific histone H1t gene that maps to the middle of the cluster. All nine histone H3 genes in this cluster have been sequenced, and their level of expression determined. Each histone H3 gene is distinct, with five genes encoding the H3.2 protein subtype and four genes encoding the H3.1 protein. They are all expressed, with each histone H3 gene accounting for a small proportion of the total histone H3 mRNA.
Device design methodology to optimize low-frequency noise in advanced SOI CMOS technology for RF ICs (2002)

This paper reports on a comprehensive study of low-frequency (LF) noise in surface-channel dual-poly SOI CMOS-FETs. A new understanding of the pre-kink and post-kink excess noise mechanisms as well as the impact of this excess noise on RF ICs are presented.
A Recyclable Fluorous (<i>S</i>)-Pyrrolidine Sulfonamide Promoted Direct, Highly Enantioselective Michael Addition of Ketones and Aldehydes to Nitroolefins in Water (2006)

[reaction: see text] A recycle and reusable fluorous (S)-pyrrolidine sulfonamide organocatalyst has been developed for promoting highly enantio- and diastereoselective Michael addition reactions of ketones and aldehydes with nitroolefins in water. The organocatalyst is conveniently recovered from the reaction mixtures by fluorous solid-phase extraction and can be subsequently reused (up to six cycles) without a significant loss of catalytic activity and stereoselectivity.
Men with Low Serum Cholesterol Have a Lower Risk of High-Grade Prostate Cancer in the Placebo Arm of the Prostate Cancer Prevention Trial (2009)

These prospective results support that men with low cholesterol have a reduced risk of high-grade prostate cancer. These and other contemporary data that suggest that cholesterol metabolism should be investigated further in the etiology of prostate cancer.
Capacitor Clamped Current Sharing Circuit for Multi-String LEDs (2013)

高亮度发光二极管(LED)自身导通压降的离散性及负温度系数特性使得多个LED串并联时出现各串电流不均衡的现象。提出了一种简洁的电容钳位型LED均流电路,各LED支路串联的开关管轮流交错导通。利用各LED支路间跨接的钳位电容在一个周期内的电荷守恒,实现了多路LED串的均流。对电路的均流原理、参数设计进行了详细的理论分析,在此基础上,进行了三支路均流的实验验证,实验结果表明所提出的电路具有良好的均流效果,控制方式简单,电容、开关管两端电压应力低,无磁性元件,便于集成。
Faecal and serum metabolomics in paediatric inflammatory bowel disease (2016)

Characterization of inflammatory pattern using metabolomics analysis is a promising tool for better understanding disease pathogenesis of paediatric IBD.
Los Gobiernos cesante y en funciones en el ordenamiento constitucional español (2005)

Sumario: I. PLANTEAMIENTO GENERAL DEL TEMA.—II. CAUSAS QUE DETERMINAN EL INICIO DEL CESE DEL GOBIERNO EN FUNCIONES.—2.1. La celebración de elecciones generales.—2.2. La pérdida de la confianza parlamentaria.—2.3. La dimisión del Presidente del Gobierno.—2.4. El fallecimiento del Presidente del Gobierno.—2.5. ¿Existen otras causas de cese además de las previstas en el artículo 101.1 CE?—2.5.1. La incapacidad del Presidente del Gobierno.—2.5.2. Procesamiento y condena penal del Presidente del Gobierno.—III. JUSTIFICACIÓN DEL PERÍODO «EN FUNCIONES» DEL GOBIERNO.—3.1. La composición del Gobierno en funciones.—3.2. Ámbito de actuación positiva del Gobierno en funciones.—IV. LÍMITES DEL GOBIERNO EN FUNCIONES.—4.1. Consideraciones previas.—4.2. Las prohibiciones establecidas en el artículo 21 de la Ley del Gobierno.—4.2.1. Las prohibiciones previstas en la Ley del Gobierno respecto del Presidente del Gobierno.—4.2.2. Las prohibiciones previstas en la Ley del Gobierno respecto del Gobierno en su conjunto.—V. UN APUNTE SOBRE EL CONTROL DEL GOBIERNO EN FUNCIONES.—VI. CONCLUSIONES.—VII. BIBLIOGRAFÍA.
Tissue Cultures of Maize (<i>Zea mays</i> L.): Initiation, Maintenance, and Organic Growth Factors<sup>1</sup> (1974)

Callus from 17 of 23 single crosses and 10 of 17 inbreds of Zea mays L. was isolated from mature embryos grown on Linsmaier and Skoog RM medium with 15 mg 2,4‐dichlorphenoxyacetic acid (2,4‐D) per liter. This callus growth was greatest from the first node of the seedling shoot; occasionally callus growth was observed from the radicle and coleoptile regions. All callus was easily transferred and maintained on media with 2 mg 2,4‐D/liter. Genetic variability for callus growth was observed among both single crosses and inbreds. Callus was initiated from 70% of 23 single crosses tested and from only 40% of the 17 inbreds tested. The most rapidly growing cultures were isolated from Oh51A ✕ Os420 which had a 20‐ to 25‐fold fresh‐weight increase during a 30‐day incubation at 30 C. Cultures maintained on 2,4‐D did not require cytokinins for growth, nor was 2,4‐D effectively replaced by idoleacetic acid or α‐napthaleneacetic acid. Several complex media additives were studied and only 800 mg yeast extract/liter and 200 mg casamino acids/liter individually stimulated significant increases in fresh weight over unsupplemented media. The callus from Oh51A ✕ Os420 has been maintained for 20 months with transfer to fresh media every 30 days (representing 19 subcultures).
Development of Extrusion Molded Nd-Fe-B Magnets (1993)

A new manufacturing process for extrusion molded magnets, composed of isotropic Nd-Fe-B powder and NyIon-12, has been developed. This newly developed extrusion molding process has several interesting features. First, the extruded product contains 72% by volume magnetic powder and yields a (BH) <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">max</inf> of 8.0 MGOe. Second, through the addition of an anti-oxidant, the viscosity of the magnetic powder-nylon compound remains almost constant during molding. Third, by means of a specially cooled outlet, which is separated from the heated die by a thermal insulator, an optimized temperature profile is obtained which yields uniformly smooth extrusion molded magnets. Both long thin-walled magnets and small arc-shaped ("kawala") magnets are easily molded by this new process.
Resolving Integer Ambiguity of GPS Carrier Phase Difference (2010)

A new approach to resolve integer ambiguity and achieve instantaneous spacecraft attitude from phase information of Global Positioning System (GPS) signals, without requiring independent attitude information from traditional attitude sensors is presented. A newly approached algorithm based on Gram-Schmidt orthonormalisation (GSO) is proposed for medium length baseline observations. By using a newly developed attitude algorithm from vector observations, an instantaneous estimated attitude is obtained from only four phase measurements collected from only two baseline observations. The implemented algorithms are tested with flight data collected onboard a mini-satellite orbiting in low Earth orbit. The results show that a coarse attitude solution is achieved from phase information of stand-alone GPS signals.
Anti-3-[ <sup>18</sup> F]FACBC Positron Emission Tomography-Computerized Tomography and <sup>111</sup> In-Capromab Pendetide Single Photon Emission Computerized Tomography-Computerized Tomography for Recurrent Prostate Carcinoma: Results of a Prospective Clinical Trial (2013)

Better diagnostic performance was noted for anti-3-[(18)F]FACBC positron emission tomography-computerized tomography than for (111)In-capromab pendetide single photon emission computerized tomography-computerized tomography for prostate carcinoma recurrence. The former method detected significantly more prostatic and extraprostatic disease.
Nanometer resolution of three-dimensional motions using video interference microscopy (1999)

An interferometric video system for measuring microelectromechanical systems (MEMS) with nanometer resolution is demonstrated. Interferograms are generated by combining light reflected from the target with light reflected from a reference mirror. Motions are determined from sequences of stop-action interferograms obtained with stroboscopic illumination. The system was used to measure motions of a microfabricated accelerometer. In-plane motions were determined by analysis of brightfield images using gradient methods with subpixel resolution. Results are compared for brightfield images obtained by blocking light from the reference arm of the interferometer and for brightfield images reconstructed from interferograms. Out-of-plane motions are determined by analyzing interferograms obtained with different positions of the reference mirror. Results demonstrate nanometer resolution of in-plane motions and subnanometer resolution of out-of-plane motions.
Differential Thermal Analysis and Simultaneous Gas Analysis (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDifferential Thermal Analysis and Simultaneous Gas AnalysisC. B. Murphy, J. A. Hill, and G. P. SchacherCite this: Anal. Chem. 1960, 32, 10, 1374Publication Date (Print):September 1, 1960Publication History Published online1 May 2002Published inissue 1 September 1960https://pubs.acs.org/doi/10.1021/ac60166a054https://doi.org/10.1021/ac60166a054research-articleACS PublicationsRequest reuse permissionsArticle Views40Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Utopia and Education in Critical Theory (2006)

In this article the author examines the intimate connections between utopia and education in Frankfurt School critical theory. Although substantial links have been made in the critical pedagogy tradition between education, critique, and utopian dreaming, an in-depth analysis of the utopia–education matrix in the works of Herbert Marcuse, Theodor Adorno, and Fredric Jameson enriches our current understanding of this topic in several key ways. Marcuse enables us to envision play as a possible praxis for revitalizing utopian longings while Adorno's focus on anxiety offers a sound corrective to the overemphasis on hope in utopian scholarship. Finally, Jameson mediates many of the differences arising between Marcuse and Adorno to fashion a post-utopian utopianism for late capitalism.
ACCELERATION OF VORTEX METHODS CALCULATION USING FMM AND MDGRAPE-3 (2011)

The present study discusses some numerical techniques on the simultaneous use of the Fast Multipole Method (FMM) and special-purpose computer (MDGRAPE-3) to make the impractically expensive calculation feasible without the loss of numerical accuracy. In the present calculations, the impingement of two identical inclined vortex rings has been studied, and the computation time has been reduced by a factor of 1000 at N = 1:18£10 6 where N is the number of vortex elements. The direct and MDGRAPE-3 calculations both have a scaling of O(N 2 ), and the use of the FMM brings them both down to O(N). The global kinetic energy, enstrophy and energy spectra have been investigated to address the numerical accuracy and have good agreement with other similar works.
The Cytoplasmic Tail of FcγRIIIAα Is Involved in Signaling by the Low Affinity Receptor for Immunoglobulin G (1996)

The low affinity receptor for IgG, FcgammaRIIIA, is a multimeric receptor composed of the ligand binding subunit FcgammaRIIIAalpha (CD16) in association with the signal-transducing subunits zeta or gamma. Previous studies suggested that the cytoplasmic tail of FcgammaRIIIAalpha was not required for FcgammaRIIIAalpha-zeta association or signaling by FcgammaRIIIA. However, in these studies, the truncated FcgammaRIIIAalpha chains still expressed the four most membrane-proximal amino acids of the cytoplasmic tail (amino acids 230-233). By successive truncations from the C terminus of FcgammaRIIIAalpha, we have studied the role played by the membrane-proximal amino acids of the cytoplasmic tail of FcgammaRIIIAalpha in (i) FcgammaRIIIA expression, (ii) FcgammaRIIIAalpha-zeta association, and (iii) signal transduction. We provide evidence that this region is not required for FcgammaRIIIA expression or FcgammaRIIIAalpha-zeta association. However, signaling by FcgammaRIIIA is strictly dependent on the membrane-proximal amino acids in the cytoplasmic tail of FcgammaRIIIAalpha. Thus, total deletion of the cytoplasmic tail of FcgammaRIIIAalpha results in a severely impaired tyrosine phosphorylation of phospholipase C-gamma1, zap, and syk and rise in intracellular free Ca2+ following receptor ligation with specific anti-CD16 monoclonal antibody or Ig-anti-Ig complexes, suggesting that FcgammaRIIIAalpha-zeta association per se is not sufficient to establish the signal function of FcgammaRIIIA. In conclusion, the present findings demonstrate that the most membrane-proximal amino acids of the FcgammaRIIIAalpha cytoplasmic tail play a critical role in ligand-induced signal transduction by the FcgammaRIIIAalpha-zeta complex.
High-Directivity Enhancement With Passive and Active Bypass Circuit Techniques for GaAs MMIC Microstrip Directional Couplers (2011)

This paper describes monolithic microwave integrated circuit microstrip directional couplers based on a new directivity enhancement technique. This technique utilizes a bypass circuit-a phase shifter and an attenuator-placed between the coupling and isolation ports to cancel out backward wave leakage to the coupling port, thereby enhancing directivity of the couplers. The bypass circuit can be implemented with a simple passive LCR circuit or an active heterojunction bipolar transistor (HBT) phase-inversion attenuation circuit. Edge-coupled-type microstrip spiral couplers using the passive and active bypass circuits were fabricated in a GaAs HBT process. Measurements are as follows. The coupler with the passive LCR bypass circuit delivers a -21-dB coupling factor and a 0.14-dB insertion loss (IL) at 2.6 GHz while keeping enhanced directivity of more than 30 dB with a 23.1% relative bandwidth. This corresponds to more than 21-dB improvement of directivity at the same frequency, compared to the coupler without the bypass circuit. For the coupler with the active attenuator, a peak directivity of 46 dB and more than 30-dB directivity with a 120% relative bandwidth are achieved while a -21-dB coupling factor and a 0.13-dB IL are delivered at 2 GHz. Additional measurements of HBT power detectors integrated with the couplers show that the couplers with passive and active bypass circuits can suppress detection errors of less than ±0.20 and ±0.10 dB, respectively, under 4:1 voltage standing-wave ratio load mismatching conditions, thus proving the effectiveness of the bypass techniques.
Primary Health Care (2002)

Primary health care has utility for policy development at all levels of organization in any nation, including policies influencing the health of persons living with severe and persistent mental illnesses. Using the primary health care framework, policies to improve health and housing for this population evolve from intersectoral collaboration. Active participation by those persons whose essential health is compromised by housing that is not acceptable, adequate, suitable, and affordable is required. Appropriate and affordable methods that address health challenges are identified. Access to services meeting essential health care needs of citizens has potential for healthy outcomes.
Augmented Bone Regeneration Activity of Platelet-Rich Plasma by Biodegradable Gelatin Hydrogel (2005)

The bile salts secretion was studied in ten normal subjects and sixteen patients with alcoholic cirrhosis, in a basal period and during 60 minutes after Secretin injection. Total bile salts were measured by a modification of the enzymatic method of Iwata and Yamasaki and the individual bile salts were separated by silica gel thin-layer chromatography. During the 60 minutes after Secretin the mean concentration was 2.88 +/- 2.58 muM/ml in normals and 1.96 +/- 1.25 muM/ml in cirrhotics. The difference is not significant. During the first 20 minutes however the concentration was higher than 3 muM/ml in 8 out of 10 normals and lower than 2 muM/ml in 10 out 16 cirrhotics. The ratios of tri-to dihydroxy bile salts was similar in both groups. The ratios between bile salts conjugated with glycine and with taurine was higher in normals, and the ratio between free to conjugated bile salts was higher in cirrhotics. The lower concentration of total bile salts immediatly after Secretin, the higher proportion of taurin conjugates and of free bile salts could be important factors in the difficulties of fact digestion and absorption frequently found in patients with alcoholic cirrhosis.
<scp>TAM</scp> receptor tyrosine kinases as emerging targets of innate immune checkpoint blockade for cancer therapy (2017)

Cancer immunotherapy utilizing T-cell checkpoint inhibitors has shown tremendous clinical success. Yet, this mode of treatment is effective in only a subset of patients. Unresponsive patients tend to have non-T-cell-inflamed tumors that lack markers associated with the activation of adaptive anti-tumor immune responses. Notably, elimination of cancer cells by T cells is critically dependent on the optimal activity of innate immune cells. Therefore, identifying new targets that regulate innate immune cell function and promote the engagement of adaptive tumoricidal responses is likely to lead to the development of improved therapies against cancer. Here, we review the TAM receptor tyrosine kinases-TYRO3, AXL, and MERTK-as an emerging class of innate immune checkpoints that participate in key steps of anti-tumoral immunity. Namely, TAM-mediated efferocytosis, negative regulation of dendritic cell activity, and dysregulated production of chemokines collectively favor the escape of malignant cells. Hence, disabling TAM signaling may promote engagement of adaptive immunity and complement T-cell checkpoint blockade.
Isolation and characterization of respiratory-deficient mutants of Escherichia coli K-12 (1988)

Several mutants of Escherichia coli K-12 defective in aerobic metabolism were isolated. One such mutant was found to be deficient in cytochromes, heme, and catalase. Aerobically grown cells did not consume oxygen and could grow only on fermentable carbon sources. Supplementation of the growth medium with delta-aminolevulonic acid, protoporphyrin IX, or hemin did not restore aerobic metabolism. The lack of heme and catalase in mutant cells grown on glucose was not due to catabolite repression, since the addition of exogenous cyclic AMP did not restore the normal phenotype. When grown aerobically on complex medium containing glucose, the mutant produced lactic acid as the principal fermentation product. This pleotropic mutation was attributed to an inability of the cells to synthesize heme, and preliminary data mapped the mutation to between 8 and 13 min on the E. coli genome.
450 mm Silicon: An Opportunity and Wafer Scaling (2006)

Today, we take our favorite music and movies anywhere. It is a result of the never-ending reduction in bit cost brought about by the accelerating development of semiconductor devices and their production technology.
Stiripentol in <scp>D</scp>ravet syndrome: Results of a retrospective <scp>U</scp>.<scp>S</scp>. study (2013)

Stiripentol is an effective and well-tolerated therapy that markedly reduced frequency of prolonged seizures in Dravet syndrome.
Defective EBV-Specific Suppressor T-Cell Function in Rheumatoid Arthritis (1981)

Several lines of evidence, including high antibody titers to Epstein-Barr virus (EBV)-associated antigens and rapid transformation of B cells into lymphoblastoid cells lines, suggest an association between EBV and rheumatoid arthritis. When lymphocytes from normal immune donors were infected with EBV in culture, they produced an exponentially increasing number of immunoglobulin-secreting cells for eight to 10 days. Thereafter, there was a marked late suppression of their response, mediated by immunoregulatory T cells; by 12 days in culture, this suppression averaged 90 per cent. Lymphocytes from 20 EBV-immune patients with rheumatoid arthritis also responded with increasing production of immunoglobulin-secreting cells, but the late suppression expected in immune donors was absent. Tests of several other T-cell functions in these patients gave normal results, suggesting a more restricted defect in suppressor-T cell function relating specifically to EBV. Since EBV persists in host B cells and thus represents a potential stimulus for immunoglobulin production, this persistence, along with a specific regulatory T-cell defect, may contribute to many of the immune abnormalities underlying rheumatoid arthritis.
Familial occurrence of tardive dyskinesia (2001)

A family history of TD might represent a risk factor for TD, whereas a family history of schizophrenia does not.
Parenteral Application of a <i>Pseudomonas aeruginosa</i> Flagella Vaccine Elicits Specific Anti-Flagella Antibodies in the Airways of Healthy Individuals (1995)

To test the hypothesis that a Pseudomonas aeruginosa flagella (FLA) vaccine, intramuscularly administered, elicits specific antibodies in the respiratory tract, antibody titers against FLA were determined in sera and bronchoalveolar lavage (BAL) fluids of 10 healthy human adults before and after immunization. Immunization produced significantly increased anti-FLA antibody titers in all sera (mean reciprocal titers: IgG: 26,711; IgA: 2,767; IgM: 421) and on respiratory epithelial lining fluids (mean reciprocal titers: IgG: 112; IgA: 76; slgA: 26). Significant differences in class-specific serum and BAL anti-FLA titers suggested airway antibody production. The study shows that parenteral immunization provides not only high systemic antibody titers but also local antibody production in the human respiratory tract.