gebhart/patrepeval huggingface dataset:
Staining properties and stability of a standardised Romanowsky stain. (1978)

An evaluation of the standardised Romanowsky stain of Marshall et al. has been made in a routine haematology laboratory. It was noted that this stain had several advantages over the May-Grünwald Giemsa stain used in most British laboratories. These advantages include ease and speed of preparation, a shorter staining time, and reproducibility of results. These results are described in detail. The stability of the stock stain solution and of the 'working' stain (stock + buffer) has been studied by, respectively, thin-layer chromatography and visible spectroscopy. No change was detected in the composition of the stock solution at ambient temperature over a period of six months. Stability was unaffected by the composition of the container (polyethylene, PyrexTM, or soda-glass) or by daylight. The 'working' solution was stable for 3 hours. Thereafter a precipitate is formed, consisting of thiazine dyes and eosin in a molar ratio of approximately 2:1.
Impacts of the Fukushima Nuclear Power Plants on Marine Radioactivity (2011)

The impacts on the ocean of releases of radionuclides from the Fukushima Dai-ichi nuclear power plants remain unclear. However, information has been made public regarding the concentrations of radioactive isotopes of iodine and cesium in ocean water near the discharge point. These data allow us to draw some basic conclusions about the relative levels of radionuclides released which can be compared to prior ocean studies and be used to address dose consequences as discussed by Garnier-Laplace et al. in this journal. The data show peak ocean discharges in early April, one month after the earthquake and a factor of 1000 decrease in the month following. Interestingly, the concentrations through the end of July remain higher than expected implying continued releases from the reactors or other contaminated sources, such as groundwater or coastal sediments. By July, levels of (137)Cs are still more than 10,000 times higher than levels measured in 2010 in the coastal waters off Japan. Although some radionuclides are significantly elevated, dose calculations suggest minimal impact on marine biota or humans due to direct exposure in surrounding ocean waters, though considerations for biological uptake and consumption of seafood are discussed and further study is warranted.
Micro vision based cell motility analyzing algorithm by optically-induced dielectrophoresis (2012)

To analyze the observed cell motility in an optically induced dielectrophoretic force, this paper describes an optical flow based automatic cell motion tracking algorithm. The optical flow measurement in the microscopic video sequences is used to estimate the 3D motion in the dielectrophoresis force fields, including rotation and translational motion. The rotation speed of the cells can be estimated automatically by analyzing each frame of a video sequences. When compare to the more tedious manual estimation process, it has been demonstrated to accurately calculate the ODEP-induced rotation rate of the cell at various applied voltages, frequencies, and waveforms. This micro vision based analyzing algorithms used for the automatic cell kinetic analysis will facilitate transfer of laboratory experiments to the automatic clinical diagnosis.
Protein Knockdown Technology: Application of Ubiquitin Ligase to Cancer Therapy (2016)

Selective degradation of pathogenic proteins by small molecules in cells is a novel approach for development of therapeutic agents against various diseases, including cancer. We and others have developed a protein knockdown technology with a series of hybrid small compounds, called SNIPERs (Specific and Nongenetic IAP-dependent Protein ERasers); and peptidic chimeric molecules, called PROTACs (proteolysis-targeting chimeric molecules), which induce selective degradation of target proteins via the ubiquitin-proteasome pathway. These compounds include two different ligands connected by a linker; one is a ligand for a ubiquitin ligase and the other is a ligand for the target protein, which are expected to crosslink these proteins in cells. Theoretically, any cytosolic protein can be targeted for degradation by this technology. To date, several SNIPERs and PROTACs against various oncogenic proteins have been developed, which specifically induce polyubiquitylation and proteasomal degradation of the oncogenic proteins, resulting in cell death, growth arrest, or impaired migration of cancer cells. Thus, this protein knockdown technology has a great potential for cancer therapy.
MTA Is an <i>Arabidopsis</i> Messenger RNA Adenosine Methylase and Interacts with a Homolog of a Sex-Specific Splicing Factor  (2008)

N6-Methyladenosine is a ubiquitous modification identified in the mRNA of numerous eukaryotes, where it is present within both coding and noncoding regions. However, this base modification does not alter the coding capacity, and its biological significance remains unclear. We show that Arabidopsis thaliana mRNA contains N6-methyladenosine at levels similar to those previously reported for animal cells. We further show that inactivation of the Arabidopsis ortholog of the yeast and human mRNA adenosine methylase (MTA) results in failure of the developing embryo to progress past the globular stage. We also demonstrate that the arrested seeds are deficient in mRNAs containing N6-methyladenosine. Expression of MTA is strongly associated with dividing tissues, particularly reproductive organs, shoot meristems, and emerging lateral roots. Finally, we show that MTA interacts in vitro and in vivo with At FIP37, a homolog of the Drosophila protein FEMALE LETHAL2D and of human WILMS' TUMOUR1-ASSOCIATING PROTEIN. The results reported here provide direct evidence for an essential function for N6-methyladenosine in a multicellular eukaryote, and the interaction with At FIP37 suggests possible RNA processing events that might be regulated or altered by this base modification.
Vehicle health management research for legacy and future operational environments (2002)

The Air Force will require the ability to diagnose and predict component failures in order to more effectively meet the requirements of the fast and agile Aerospace Expeditionary Force (AEF) and future space vehicles. This paper will cover topics relevant to vehicle health management for current and anticipated support environments. It reflects current projects underway at the Air Force Research Laboratory in the air vehicles and human effectiveness directorates. Specifically, the predictive failures and advanced diagnostics (PFAD) for legacy aircraft, passive aircraft status system (PASS), and the space operations vehicle integrated system (SOVIS) projects will be discussed.
Nanoparticle-doped Electrically-conducting Polymers for Flexible Nano-Micro Systems (2012)

The problem of micro-cracking associated with integrated flexible-polymer and metal-surfaces due to material mismatch has been discussed. To alleviate the problem of micro-cracking, the use of conducting nanocomposite polymers with a hybrid fabrication process is suggested. This approach keeps intact the flexibility of the polymer while imparting conductivity to it. PDMS (polydimethyl-silioxane), an insulating polymer, is doped with conducting nanoparticles (carbon nanotubes) by a 5 step process. Three mechanisms for the dispersion of nanoparticles in the polymer matrix have been discussed, namely ultrasonic agitation, shear mixing, and ball milling, of which ultrasonic agitation is considered to be the most effective. The use of a hybrid fabrication technique against a SU-8 mold to prepare an electrically-conducting nanocomposite structure combined with nonconductive PDMS is also discussed.
A Method of Measuring Poisson's Ratio of Fibers1 (1958)

An apparatus is described whereby Poisson's ratio may be measured for fibers whose diameter is approximately 250μ. The apparatus is used in conjunction with an Instron Testing Machine so that stress vs. strain measurements can be made at the same time Poisson's ratio vs. strain measurements are made. The measurements can be made statically or on fibers undergoing a constant rate of extension. Measurements on four different tilaments of drawn nylon 66 gave (above 1% strain) a constant value of 0.392 ± 0.025 for Poisson's ratio. (An extension rate of 0.02 in min. and an initial gauge length of about 40 cm. were used.) In general there is an increase of Poisson's ratio starting with about 0.34 at low strains and increasing to a final value of 0.392 at about 1% strain. Concurrent with the change in Poisson's ratio there is a change in the tangent modulus of the stress-strain curve.
Asymmetric Synthesis of Isoquinoline Alkaloids: 2004–2015 (2016)

In the past decade, the asymmetric synthesis of chiral nonracemic isoquinoline alkaloids, a family of natural products showing a wide range of structural diversity and biological and pharmaceutical activity, has been based either on continuation or improvement of known traditional methods or on new, recently developed, strategies. Both diastereoselective and enantioselective catalytic methods have been applied. This review describes the stereochemically modified traditional syntheses (the Pictet-Spengler, the Bischler-Napieralski, and the Pomeranz-Fritsch-Bobbitt) along with strategies based on closing of the nitrogen-containing ring B of the isoquinoline core by the formation of bonds between C<sub>1</sub>-N<sub>2</sub>, N<sub>2</sub>-C<sub>3</sub>, C<sub>1</sub>-N<sub>2</sub>/N<sub>2</sub>-C<sub>3</sub>, and C<sub>1</sub>-N<sub>2</sub>/C<sub>4</sub>-C<sub>4a</sub> atoms. Methods involving introduction of substituents at the C1 carbon of isoquinoline core along with syntheses applying various biocatalytic techniques have also been reviewed.
Palladium‐Catalyzed Synthesis and Isolation of Functionalized Allylboronic Acids: Selective, Direct Allylboration of Ketones (2012)

Textbook revision: allylboronic acids, which are easily prepared from allylic alcohols, react readily and selectively with ketones without Lewis acid catalysts.
Advances in DMD-based UV application reliability below 320nm (2010)

Texas Instrument's spatial light modulator chip, the DMD (digital micromirror device, the central chip in all DLP based systems) has been used in multiple maskless lithography applications for the past 5-7 years. Typically these applications have been focused on PCB lithography. Applications using illumination below 320nm have not been feasible due to shortened lifetime of the device at shorter wavelengths. Recent advances in DMD processing have made significant improvements in the operational lifetime of the DMD. This paper will cover the background of UV-A DMD maskless lithography and demonstrate the increased lifetime at 311nm and 266nm with the new processes.
CD4 T Lymphocytes from Patients with Chronic Fatigue Syndrome Have Decreased Interferon‐γ Production and Increased Sensitivity to Dexamethasone (1998)

A disturbed hypothalamus-pituitary-adrenal gland axis and alterations at the immune system level have been observed in patients with chronic fatigue syndrome (CFS). Glucocorticoids are known to modulate T cell responses; therefore, purified CD4 T cells from CFS patients were studied to determine whether they have an altered sensitivity to dexamethasone (DEX). CD4 T cells from CFS patients produced less interferon-gamma than did cells from controls; by contrast, interleukin-4 production and cell proliferation were comparable. With CD4 T cells from CFS patients (compared with cells from controls), a 10- to 20-fold lower DEX concentration was needed to achieve 50% inhibition of interleukin-4 production and proliferation, indicating an increased sensitivity to DEX in CFS patients. Surprisingly, interferon-gamma production in patients and controls was equally sensitive to DEX. A differential sensitivity of cytokines or CD4 T cell subsets to glucocorticoids might explain an altered immunologic function in CFS patients.
Surprising Alteration of Antibacterial Activity of 5′′-Modified Neomycin against Resistant Bacteria (2008)

A facile synthetic protocol for the production of neomycin B derivatives with various modifications at the 5'' position has been developed. The structural activity relationship (SAR) against aminoglycoside resistant bacteria equipped with various aminoglycoside-modifying enzymes (AMEs) was investigated. Enzymatic and molecular modeling studies reveal that the superb substrate promiscuity of AMEs allows the resistant bacteria to cope with diverse structural modifications despite the observation that several derivatives show enhanced antibacterial activity compared to the parent neomycin. Surprisingly, when testing synthetic neomycin derivatives against other human pathogens, two leads exhibit prominent activity against both methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) that are known to exert a high level of resistance against clinically used aminoglycosides. These findings can be extremely useful in developing new aminoglycoside antibiotics against resistant bacteria. Our result also suggests that new biological and antimicrobial activities can be obtained by chemical modifications of old drugs.
The Development of a Mobile Application in a Collaborative Banking System (2014)

This paper presents a taxonomy of mobile applications with accent on collaborative mobile applications. The development of mobile applications is described in comparison with the other types of informatics applications. Collaborative banking systems are presented in order to create the context in which the Collaborative Multicash Servicedesk (CMS) application will be integrated. The mobile applications are analyzed as auto-adaptive applications in order to reveal their advantages. Some metrics are built for evaluating the security and quality of
A Multiplicative Calderon Preconditioner for the Electric Field Integral Equation (2008)

<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> In this paper, a new technique for preconditioning electric field integral equations (EFIEs) by leveraging CalderÓn identities is presented. In contrast to all previous CalderÓn preconditioners, the proposed preconditioner is purely multiplicative in nature, applicable to open and closed structures, straightforward to implement, and easily interfaced with existing method of moments (MoM) code. Numerical results demonstrate that the MoM EFIE system obtained using the proposed preconditioning converges rapidly, independently of the discretization density. </para>
Cross‐Metathesis of 1,3‐Dienes with Electron‐Deficient Olefins. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Using Reverse Osmosis to Recycle Engine Coolant (1992)

<div class="htmlview paragraph">Reverse osmosis (RO) is a technology that has been used extensively to purity seawater into drinking water. More recently many other processes have turned to RO to cleanse and separate chemical products. This paper examines RO as a means of recycling ethylene glycol based engine coolant.</div>
A methodology for mapping scores to probabilities (1999)

Describes the derivation of probability of correctness from scores assigned by most recognizers. Derivation of probability values puts the output of different recognizers on the same scale; this makes comparison across recognizers trivial. The authors draw on examples from handwritten word recognition to illustrate their point.
3 - Compression d'image par transformée en ondelette et quantification vectorielle (1990)

The purpose of this paper is to propose a ne scheme for image compression .
Firsi, e use a a elet transform in order to obtain a set of orthonormal subclasses of images. The a elet functions are ell
locali ed both in the space and frequenc domains. The original image is decomposed on this orthonarmal basis ith a p ramidal
algorithm architecture . This d composition pri ileges hori ontal, ertical and diagonal orientations . Since a elet d composition
is based on multiresolution and pri ileged directions, il tries to match human ision .
The a elets coefficients of each classes are then ector quanti ed. A separate optimal codebook is designed for each gi en
resolution and direction using e training sequence and a MSE distortion measurment .
Then the input ector is classifaed (resolution and direction) and onl the appropriate subclass of the codebook is then checked
using the usual MSE . Thus the computational comple it is reduced.
Finall bit allocation of each class is adjusted in order to preser e edges and shapes .
Análisis de las políticas climáticas, modelo integrado del EU ETS para la industria española (2015)

El Mercado Europeo de Derechos de Emision (EU ETS) es el
principal instrumento de la Union Europea (UE) contra el cambio
climatico. Este mecanismo esta considerado, desde el punto de
vista teorico, como el metodo economicamente mas eficiente
para reducir los Gases de Efecto Invernadero (GEI). Sin
embargo, estudios previos muestran circunstancias anomalas
en el comportamiento de los agentes participantes en este tipo
de mercados, que pueden provocar ineficiencias en el precio del
CO2 y eventualmente cuestionar la efectividad del sistema. Este
trabajo analiza estas posibles anomalias mediante una
modelizacion del comportamiento racional del mercado. Para
ello se ha construido un modelo bottom-up, que representa el
EU ETS de forma integrada, prestando especial atencion a las
interacciones entre los sectores industriales mas intensivos en
emisiones. Los resultados muestran los beneficios de esta
modelizacion integrada, y su ajuste razonable a la realidad del
mercado.
A Review of Journals Dealing with the Internet (1997)

Only recently has a collection of magazines and journals emerged that are devoted solely to the Internet. This article reviews some of these periodicals as well as a few others that contain an increasing number of feature articles about the Internet. Thc periodicals selected are print publications with articles of interest to librarians. The reviews reveal the strengths of the periodicals and alert readcrs to significant columns in each.
Adiabatic Fast Passage Method for Spin-Lattice Relaxation Time Measurements (1970)

The apparatus for the adiabatic fast passage experiments used for the measurement of NMR spin-lattice relaxation times is described. The different experimental conditions and techniques for the T1 measurements of chemically shifted nuclei are briefly discussed.
Stearns, Hitchcock, and Amherst College (1957)

(1957). Stearns, Hitchcock, and Amherst College. Journal of Health, Physical Education, Recreation: Vol. 28, No. 5, pp. 29-30.
NF-kB transcription factor: a key player in the generation of immune response (2006)

Activation of the immune system is a multistep process.
The transcription factor nuclear factor-kappa B (NFkB),
has been one of the most widely studied molecules
in the immune system, as it is activated by a variety of
stimuli and it in turn controls diverse genes and biological
responses. It is an evolutionarily conserved
molecule that coordinates the organism’s response to
infection, stress and injury. It plays a major role in
the induction of pro-inflammatory genes and affects
the various cells involved in immune response as well
as affects the generation of innate and adaptive immune
response. It is also a target for drugs used in treatment
of various inflammatory diseases.
Parsimonious downgrading and decision trees applied to the inference problem (1998)

Article Free Access Share on Parsimonious downgrading and decision trees applied to the inference problem Authors: LiWu Chang Center for High Assurance Computer Systems, Mail Code 5540, Naval Research Laboratory, Washington, DC Center for High Assurance Computer Systems, Mail Code 5540, Naval Research Laboratory, Washington, DCView Profile , Ira S. Moskowitz Center for High Assurance Computer Systems, Mail Code 5540, Naval Research Laboratory, Washington, DC Center for High Assurance Computer Systems, Mail Code 5540, Naval Research Laboratory, Washington, DCView Profile Authors Info & Claims NSPW '98: Proceedings of the 1998 workshop on New security paradigmsJanuary 1998 Pages 82–89https://doi.org/10.1145/310889.310921Published:01 January 1998Publication History 32citation435DownloadsMetricsTotal Citations32Total Downloads435Last 12 Months19Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Acoustic enhancement of sleep slow oscillations in mild cognitive impairment (2019)

Acoustic stimulation delivered during slow-wave sleep over one night was effective for enhancing SWA in individuals with aMCI. Given established relationships between SWA and memory, a larger or more prolonged enhancement may be needed to consistently improve memory in aMCI.
Chapter 2: Plasma confinement and transport (2007)

The understanding and predictive capability of transport physics and plasma confinement is reviewed from the perspective of achieving reactor-scale burning plasmas in the ITER tokamak, for both core and edge plasma regions. Very considerable progress has been made in understanding, controlling and predicting tokamak transport across a wide variety of plasma conditions and regimes since the publication of the ITER Physics Basis (IPB) document (1999 Nucl. Fusion 39 2137-2664). Major areas of progress considered here follow. (1) Substantial improvement in the physics content, capability and reliability of transport simulation and modelling codes, leading to much increased theory/experiment interaction as these codes are increasingly used to interpret and predict experiment. (2) Remarkable progress has been made in developing and understanding regimes of improved core confinement. Internal transport barriers and other forms of reduced core transport are now routinely obtained in all the leading tokamak devices worldwide. (3) The importance of controlling the H-mode edge pedestal is now generally recognized. Substantial progress has been made in extending high confinement H-mode operation to the Greenwald density, the demonstration of Type I ELM mitigation and control techniques and systematic explanation of Type I ELM stability. Theory-based predictive capability has also shown progress by integrating the plasma and neutral transport with MHD stability. (4) Transport projections to ITER are now made using three complementary approaches: empirical or global scaling, theory-based transport modelling and dimensionless parameter scaling (previously, empirical scaling was the dominant approach). For the ITER base case or the reference scenario of conventional ELMy H-mode operation, all three techniques predict that ITER will have sufficient confinement to meet its design target of Q = 10 operation, within similar uncertainties.
Transport properties of holes in bulk InAsSb and performance of barrier long-wavelength infrared detectors (2014)

A new method for determination of minority carrier lifetimes, mobilities and diffusion lengths is demonstrated. From the transient response of long wavelength infrared barrier detectors with a cut-off of 10 micron, the mobility of the minority holes and their lifetime in bulk InAs0.6Sb0.4 at T = 77 K was determined to be 800 cm2 V−1s−1 and 165 ns, respectively.