gebhart/patrepeval huggingface dataset:
Formation of bonds to O, S, Se, Te, Po (1998)

Formation of the Group VIB (O,S,Se,Te,Po) -- Group IB (Cu,Ag,Au) or IIB (Zn,Cd,Hg) Metal Bond. Formation of Bond Between the Group VIB (O,S,Se,Te,Po) Elements and Transition and Inner Transition Metals. Formation of the Bond Between Group VIB (O,S,Se,Te,Po) and Group O (Noble Gas) Elements. Formation of Non--stoichiometric Oxides. Formation of the Nonstoichiometric Sulfides, Selenides, and Tellurides. Abbreviations. Indexes.
Total Synthesis of ( ± )-α-Cubebene and ( ± )-β-Cubebene (1971)

An efficient total synthesis of the racemic forms of the novel tricyclic sesquiterpenes α-cubebene (1) and β-cubebene (2) is described. The key step of this synthesis involved the cupric sulfate catalyzed intramolecular cyclization of the olefinic diazoketone 3, which produced, in high yield, ( ± )-β-cubebene norketone (24) and ( ± )-1,6-epi-β-cubebene norketone (25), in a ratio of approximately 3:5, respectively.
Pilot disorientation during aircraft catapult launchings at night - Historical and experimental perspectives (1992)

A review is presented of the investigations conducted into, and the recommendations made to avoid fatal A-7 Corsair II aircraft accidents during night carrier launchings in which the aircraft was apparently flown into the water. The investigating boards conjectured that the pilots were distracted from their normal cockpit procedures and that the distraction was of an insidious nature not previously experienced or expected in the night catapult/departure environment. A conference to discuss these accidents focused on aerodynamic and human factors analyses of the problem, with the goal of producing several recommendations for its resolution.
A FACILE ROUTE FOR THE PREPARATION OF N-PHENYL TETRAHYDROQUINOLINES AND TETRAHYDROISOQUINOLINES (2001)

A convenient N-arylation of tetrahydroquinoline and tetrahydroisoquinoline is described using electron-poor, electron-neutral, or electron-rich arylhalide derivatives and palladium(II)-BINAP as a catalyst.
Comparison of the Efficacy, Toxicity, and Pharmacokinetics of a Uracil/Tegafur (UFT) Plus Oral Leucovorin (LV) Regimen Between Japanese and American Patients With Advanced Colorectal Cancer: Joint United States and Japan Study of UFT/LV (2004)

The efficacy and pharmacokinetic parameters of UFT and LV are comparable in Japanese and American patients; however, a difference in toxicity profile, specifically diarrhea, was noted. This oral regimen of UFT and LV is considered to have similar activity against metastatic colorectal cancer and to have acceptable toxicity in patients in both countries.
A Developmental Change in NMDA Receptor-Associated Proteins at Hippocampal Synapses (2000)

The membrane-associated guanylate kinases [Chapsyn-110/postsynaptic density-93 (PSD-93), synapse-associated protein-90 (SAP-90)/PSD-95, and SAP-102] are believed to cluster and anchor NMDA receptors at the synapse and to play a role in signal transduction. We have investigated the developmental changes in expression of these proteins in rat hippocampus using biochemical analyses and quantitative immunogold electron microscopy. At postnatal day 2 (P2), SAP-102 was highly expressed, whereas PSD-93 and PSD-95 were low. SAP-102 expression increased during the first week, stayed stable through P35, and showed a reduced expression at 6 months. From P2 through 6 months, PSD-93 and PSD-95 increased. For PSD-95, the percent of labeled synapses increased almost threefold with age, whereas the number of gold particles per labeled synapse did not change significantly, suggesting that the increase in PSD-95 is attributable primarily to an increase in the number of synapses containing PSD-95. In contrast, for SAP-102, both percent labeled synapses and the number of gold particles per labeled synapse decreased during this time. From Western blots of hippocampus and immunogold analysis of CA1 synapses, the high expression of NR2B at P2 coincides with the high level of SAP-102 at synapses, whereas the later expression of NR2A coincides with that of PSD-93 and PSD-95. To determine whether the changes in PSD-93/95 and SAP-102 reflect preferred associations with NR2A and NR2B, respectively, we measured co-immunoprecipitation in the adult hippocampus. These studies suggest that there is a preference for complexes of NR2A/PSD-93/95 and NR2B/SAP-102. These results indicate that individual receptor-associated proteins may have specific functions that are critical to synapse development.
Utilizing high-throughput experimentation to enhance specific productivity of an E.coliT7 expression system by phosphate limitation (2011)

The results revealed that a phosphate limitation at the right induction time was suitable to redirect the available cellular resources during cultivation to protein expression rather than in biomass production. To our knowledge, such an effect was shown for the first time for an IPTG-inducible expression system. Finally, this finding and the utilization of the introduced high-throughput experimentation approach could help to find new targets to further enhance the production capacity of recombinant E.coli-strains.
Vive la difference? (1995)

What Chris Jones discovered on a study visit to a prestigious French hospital’s intensive care units was quite a revelation. Here he examines the similarities and differences with the UK
Generalized frame multiresolution analysis of abstract Hilbert spaces and their applications (2000)

We define a very generic class of multiresolution analysis of abstract Hilbert spaces. Their core subspaces have a frame produced by the action of an abelian unitary group on a perhaps infinite subset of the core subspace, which we call frame multi scaling vector set. We characterize the associated frame multi wavelet vector sets by generalizing the concept of the low and high pass filters and the Quadrature Mirror filter condition. We include an extensive overview of related work of other and we conclude with some examples.
Substrate-diamond interface considerations for enhanced thermionic electron emission from nitrogen doped diamond films (2012)

Thermionic electron emission from low work function doped diamond films can be related to materials' properties, which include donor states, surface electron affinity, and substrate-diamond interface properties. The focus of this study is on how the properties of the substrate material affect the emission. Two aspects are considered, the substrate electrical resistance and the substrate Richardson constant, and the effects of tungsten, molybdenum and rhenium substrates are explored. Low work function diamond films were deposited on the substrates, and the thermionic emission was measured to ∼530 °C and described in terms of a fit to the Richardson-Dushman formalism. The results establish that all surfaces exhibit a similar work function but the Richardson constant and maximum emission current vary considerably. The rhenium based emitter displayed a low work function of 1.34 eV, a significant Richardson constant of 53.1 A/cm2 K2, and an emission current density of ∼44 mA/cm2 at a temperature of 530 °C. The results indicated that interface carbide formation could limit the emission presumably because of increased electrical resistance. For non-carbide forming substrates, an increased substrate Richardson constant corresponded to enhanced emission from the diamond based emitter.
Effects of Ionic Surfactant Adsorption on Single-Walled Carbon Nanotube Thin Film Devices in Aqueous Solutions (2005)

Field-effect transistors were fabricated using high-density single-walled carbon nanotube (SWNT) thin films directly grown on suitable substrates. Such approach eliminated the variations of device behaviors in individual SWNT devices by utilizing a large number of SWNTs in each device. We have found that the behaviors of such devices are closely related to the surface charge densities around SWNTs in aqueous solutions. Adsorption of ionic surfactants on the surface could significantly modulate the device characteristics, which could be detected by measuring the conductance of the devices. The devices could be tuned to be sensitive to either anionic or cationic surfactants by tailoring the surface properties of SiO(2) substrates around SWNTs. This effect could be potentially used to design chemical and biological sensors.
β-Arylglutaconic Acids. IV.<sup>1</sup> Synthesis of Crotono- and Valerolactones of β-Arylglutaconic and Glutaric Acids (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTβ-Arylglutaconic Acids. IV.1 Synthesis of Crotono- and Valerolactones of β-Arylglutaconic and Glutaric AcidsJ. J. NERURKAR, R. N. JOSHI, V. N. MARATHE, G. S. PHADKE, and V. M. BHAVECite this: J. Org. Chem. 1960, 25, 9, 1491–1495Publication Date (Print):September 1, 1960Publication History Published online1 May 2002Published inissue 1 September 1960https://pubs.acs.org/doi/10.1021/jo01079a008https://doi.org/10.1021/jo01079a008research-articleACS PublicationsRequest reuse permissionsArticle Views87Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Suppression of lipid artifacts in amide proton transfer imaging (2005)

Amide proton transfer (APT) imaging is a type of chemical exchange saturation transfer imaging in which the amide protons of cellular proteins and peptides are saturated and detected via the water resonance. To study this effect, conventional magnetization transfer and direct saturation effects in the frequency-dependent water saturation spectrum (z-spectrum) need to be removed by asymmetry analysis with respect to the water frequency offset. When using echo planar imaging, it was found that unequal pericranial fat saturation at equidistant higher and lower frequencies with respect to water leads to a lipid artifact in APT asymmetry images. It is demonstrated that a chemical-shift-selective refocusing pulse in combination with crusher gradients can suppress this artifact and provide high-quality images.
Anti-CD9 monoclonal antibody-stimulated invasion of endometrial cancer cell lines in vitro: possible inhibitory effect of CD9 in endometrial cancer invasion (2000)

Cell surface marker CD9 has been reported to play a role in inhibiting trophoblastic cell invasion. Since the invasive properties of cancer cells may resemble those of trophoblasts, we decided to investigate the role of CD9 in the invasion of endometrial cancer cells. In normal human endometrium, CD9 was found to be constitutively expressed on epithelial cells, as reported previously. While epithelial cells of endometrial hyperplasia (n = 5) were also positive for the expression of CD9, endometrial adenocarcinomas (n = 15) showed reduced expression. In order to clarify the significance of this reduced CD9 expression in endometrial cancer, an in-vitro invasion assay system was used to assess the effect of anti-CD9 monoclonal antibody (mAb) on the invasive properties of endometrial cancer cell line. Anti-CD9 mAb significantly enhanced invasion of the RL95-2 and Ishikawa cell lines, without affecting cell proliferation. Since CD9 is associated with the integrin subunits beta(1), alpha(3) and alpha(6) in human endometrium, we investigated the functional relationship between CD9 and these integrins in the RL95-2 cell line. Monoclonal antibodies against the integrins beta(1), alpha(3) and alpha(6) inhibited RL95-2 cell invasion. However, anti-CD9 mAb continued to show a stimulatory effect on RL95-2 cell invasion after treatment with anti-integrin alpha(3) mAb. In contrast, the anti-CD9 mAb had no effect after treatment with the mAb for integrins alpha(6) and beta(1). These findings indicate that CD9 is involved in regulating the invasive properties of endometrial carcinoma cells and that this effect is partially mediated by integrin subunits alpha(6) and beta(1). Thus, CD9 appears to be involved in the prevention of endometrial cancer invasion.
Hydrolysis of octahydrotriborate in cold acidic methanol-water solutions. Preparation of B3H7OH2 and B3H7OH- (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHydrolysis of octahydrotriborate in cold acidic methanol-water solutions. Preparation of B3H7OH2 and B3H7OH-William L. Jolly, Janice W. Reed, and Francis T. WangCite this: Inorg. Chem. 1979, 18, 2, 377–380Publication Date (Print):February 1, 1979Publication History Published online1 May 2002Published inissue 1 February 1979https://pubs.acs.org/doi/10.1021/ic50192a035https://doi.org/10.1021/ic50192a035research-articleACS PublicationsRequest reuse permissionsArticle Views66Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Antiherpes effect of Melissa officinalis L. extracts. (1993)

Studies were carried out on the virucidal and antiviral effects of Melissa officinalis L. extracts (M1, M3, M3 and M4) with respect to Herpes simplex virus type 1 (HSV-1). Virucidal effect was registered within 3 and 6 hours of treatment using M4 administered in MTC. The remaining extracts inactivate the virus at the 12th and 24th hour. No significant values of inhibiting activity of M1, M2, and M3 on the same virus in vitro or in vivo were demonstrated. The presence of caffeic, rosmarinic and ferulic acids was demonstrated by thin-layer chromatography. Their role in the antiviral activity of M. officinalis L. is discussed.
Atomic imaging of nucleation of trimethylaluminum on clean and H2O functionalized Ge(100) surfaces (2011)

The direct reaction of trimethylaluminum (TMA) on a Ge(100) surface and the effects of monolayer H(2)O pre-dosing were investigated using ultrahigh vacuum techniques, such as scanning tunneling microscopy (STM), scanning tunneling spectroscopy (STS), and x-ray photoelectron spectroscopy (XPS), and density functional theory (DFT). At room temperature (RT), a saturation TMA dose produced 0.8 monolayers (ML) of semi-ordered species on a Ge(100) surface due to the dissociative chemisorption of TMA. STS confirmed the chemisorption of TMA passivated the bandgap states due to dangling bonds. By annealing the TMA-dosed Ge surface, the STM observed coverage of TMA sites decreased to 0.4 ML at 250 °C, and to 0.15 ML at 450 °C. XPS analysis showed that only carbon content was reduced during annealing, while the Al coverage was maintained at 0.15 ML, consistent with the desorption of methyl (-CH(3)) groups from the TMA adsorbates. Conversely, saturation TMA dosing at RT on the monolayer H(2)O pre-dosed Ge(100) surface followed by annealing at 200 °C formed a layer of Ge-O-Al bonds with an Al coverage a factor of two greater than the TMA only dosed Ge(100), consistent with Ge-OH activation of TMA chemisorption and Ge-H blocking of CH(3) chemisorption. The DFT shows that the reaction of TMA has lower activation energy and is more exothermic on Ge-OH than Ge-H sites. It is proposed that the H(2)O pre-dosing enhances the concentration of adsorbed Al and forms thermally stable Ge-O-Al bonds along the Ge dimer row which could serve as a nearly ideal atomic layer deposition nucleation layer on Ge(100) surface.
Profile of Anticonvulsant Activity and Minimal Toxicity of Methyl 4‐[(<i>p</i>‐Chlorophenyl)amino]‐6‐Methyl‐2‐Oxo‐Cyclohex‐3‐En‐l‐Oate and Some Prototype Antiepileptic Drugs in Mice and Rats (1993)

The anticonvulsant and toxic properties of methyl 4-[(p-chlorophenyl)amino]-6-methyl-2-oxocyclohex-3-en-1-oate (ADD 196022), were compared with those of phenytoin (PHT), carbamazepine (CBZ), and valproate (VPA). These compounds were evaluated in mice and rats using well-standardized anticonvulsant testing procedures. Results indicate that ADD 196022 is a very potent anticonvulsant in the maximal electroshock seizure (MES) model. The compound was effective in nontoxic doses after intraperitoneal (i.p.) administration in mice and oral administration in rats. In mice, i.p. administration of ADD 196022 resulted in an ED50 value of 26.2 mg/kg as compared with a value of 6.48 mg/kg for PHT in the same assay. ADD 196022 was more potent that PHT in the oral rat model, having an ED50 value of 5.79 mg/kg as compared to 23.2 mg/kg for PHT. ADD 196022 was ineffective in nontoxic doses against all other seizure models evaluated and thus has a pharmacologic profile similar to that of PHT.
Purification and Characterization of a Novel Xylulose 5-Phosphate-activated Protein Phosphatase Catalyzing Dephosphorylation of Fructose-6-phosphate,2-kinase:Fructose-2,6-bisphosphatase (1995)

We have shown previously (Nishimura, M., Fedorov, S., and Uyeda, K. (1994) (J. Biol. Chem. 269, 26100-26106) that the administration of high concentrations of glucose stimulates dephosphorylation of Fru-6-P,2-kinase: Fru-2,6-bisphosphatase in perfused liver, and xylulose (Xu) 5-P activates the dephosphorylation reaction. To characterize the protein phosphatase, we have purified the Xu 5-P-activated protein phosphatase to homogeneity from livers of rats injected with high glucose. Several protein phosphatases in the livers were separated by DEAE-cellulose chromatography, but only one peak of the enzyme was activated by Xu 5-P. The protein phosphatase was inhibited by okadaic acid (IC50 = 1-3 nM) and did not require Mg2+ or Ca2+, suggesting that the enzyme was type 2A. The enzyme was a heterotrimer (M(r) = 150,000) and consisted of structural (A, 65 kDa) catalytic (C, 36 kDa), and regulatory (B, 52 kDa) subunits. Amino acid sequences of five tryptic peptides derived from the B subunit showed similarity with those of the B alpha isoform of rat protein phosphatase 2A, but five out of 73 residues were different. The protein phosphatase catalyzed dephosphorylation of Fru-6-P,2-kinase:Fru-2,6-Pase, phosphorylase alpha, and pyruvate kinase, and the Km values were 0.8 microM, 3.7 microM, and 2.2 microM, respectively. Among these substrates dephosphorylation of only the bifunctional enzyme was activated by Xu 5-P, and the K alpha value for Xu 5-P was 20 microM. Xu 5-P was the only sugar phosphate which activated the PP2A among all the sugar phosphates examined. These results demonstrated the existence and isolation of a unique heterotrimeric protein phosphatase 2A in rat liver which catalyzed the dephosphorylation of Fru-6-P,2-kinase:Fru-2,6-Pase and was activated specifically by Xu 5-P. The Xu 5-P-activated protein phosphatase 2A explains the increased Fru 2,6-P2 level in liver after high glucose administration.
An inclusive system for fashion criticism (2017)

This paper serves to uncover fashion criticism as a discursive network which situates fashion in the system that goes alongside but is also different from art. In developing a cogent discourse, three types of elucidation are suggested. First, the authors identify topographies of fashion as they evolve as aesthetic components inherent in the structure of fashion. Notably, these topographies are socio-economic structures of collective fashion agents within the fashion system and are eventual cultural discourses. Second, fashion criticism is defined as linguistic analysis and interpretation of a variety of discussions around fashion and an aesthetic analysis of it. Against a lack of critical approaches to fashion, we argue that fashion criticism should be systematised as existing alongside art criticism and be reflective of fashion’s multiple facets. Third, the authors suggest an inclusive criticism model for fashion that incorporates aesthetic, socio-economic, and cultural perspectives.
Applications of diffusion-weighted magnetic resonance imaging in renal cell carcinoma (2011)

Diffusion-weighted MRI (DW-MRI) has received more attention recently, especially from uroradiologists, owing to its role in the characterization of renal lesions. Moreover, the apparent diffusion coefficient (ADC), a value calculated based on DW-MRIs, has been used to analyze renal lesions quantitatively. However, many factors influence the accuracy of the ADC value calculation during the DW-MRI procedure. In addition, it is of great interest whether DW-MRI is superior to more conventional dynamic contrast-enhanced (DCE)-MRI for the characterization of renal lesions, or whether DW-MRI combined with DCE-MRI may provide more valuable information. Here we review state-of-the-art DW-MRI for the evaluation of renal cell carcinomas, discuss factors that influence the calculation of ADC maps, examine the impact of field strength on ADC values and, finally, compare DW-MRI and DCE-MRI for imaging renal lesions.
CubicRing: enabling one-hop failure detection and recovery for distributed in-memory storage systems (2015)

In-memory storage has the benefits of low I/O latency and high I/O throughput. Fast failure recovery is crucial for large-scale in-memory storage systems, bringing network-related challenges including false detection due to transient network problems, traffic congestion during the recovery, and top-of-rack switch failures. This paper presents CubicRing, a distributed structure for cube-based networks which exploits network proximity to restrict failure detection and recovery within the smallest possible one-hop range. We leverage the Cubic-Ring structure to address the aforementioned challenges and design a network-aware in-memory key-value store called MemCube. In a 64-node 10GbE testbed, MemCube recovers 48 GB of data for a single server failure in 3.1 seconds. The 14 recovery servers achieve 123.9 Gb/sec aggregate recovery throughput, which is 88.5% of the ideal aggregate bandwidth.
Energy budget and high-gain strategies for voltage-constrained electrostatic harvesters (2009)

Wireless micro-sensors and similar technologies must derive their energy from micro-scale sources (e.g., thin-film Li Ions, etc.) to function in volume-constrained environments like the human body. Unfortunately, confining the source to small spaces limits the total energy available to such an extent that operational life is often impractically short. Ambient energy offers an alternate and virtually boundless source, except small volumes restrain harvesting power. Voltage-constrained electrostatic CMOS harvesters, for example, draw energy from the work done against the mechanical plates of a MEMS variable capacitor at relatively slow rates, producing low output power. This paper discusses how much energy is available in such a system before and after harvesting and offers energy-conservation schemes for increasing its net energy gain (i.e., power output) during all operational phases.