gebhart/patrepeval huggingface dataset:
Assessment of autonomic function and mental condition on cardio-respiratory variability and thermal regulation by using neural network (2002)

In this study, we could evaluate the relationship between autonomic function and mental condition by analysing constructed neural network. Subjective mental condition was investigated by POMS, and 3 factors called vigor, negative emotion and fatigue were used as output data for neural network. Then 19 autonomic function indicators were acquired to use as input data. Using these data sets, the feedforward neural networks were constructed on each subject. Moreover, each unit's output function of constructed networks was replaced by its linear approximate formula. By substituting the weight of constructed network for the formula, informational weights of autonomic function indicators to each mental factor were calculated. As the result, it was indicated that the sympathetic activity was dominant under vigorous condition, and autonomic nervous activity declined under fatigue condition.
Evanescent interferometry by scanning optical tunneling detection (1996)

The work reported deals with evanescent-wave interferometry. In a scanning tunneling optical microscope (STOM/PSTM) we study the interaction of an evanescent standing wave with nanometer-sized objects. Two complementary numerical models are compared with experimental results. Finally, it is shown that synthetic interferograms can be generated by use of the distinctive features of this kind of microscope.
Death of a salesman (2001)

The author suggests that executive search practitioners would be naïve to believe that the revolution being enacted within their clients’ businesses will not ultimately embrace them. More pointedly, it is argued that supporting the client’s quest to create value for its customer base will, of necessity, be the primary driving force of ongoing competitiveness. Finally, it is suggested that migrating up the value ladder has the effect of devaluing many of the characteristics of perceived differentiation that have been the wellspring of success for those in the search community.
Production of LLU-.ALPHA. Following an Oral Administration of .GAMMA.-Tocotrienol or .GAMMA.-Tocopherol to Rats. (2000)

An oral administration of gamma-tocotrienol (gamma-T3) or gamma-tocopherol (gamma-Toc) to male rats caused an increase of the concentration of 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxy chroman (LLU-alpha, gamma-CEHC), a natriuretic compound, in plasma with a T(max) of 9 h. The configuration at C-2 of LLU-alpha produced from gamma-T3 or gamma-Toc was assigned as S-form by an HPLC equipped with a chiral column. These data indicated that LLU-alpha was produced not only from gamma-Toc but also gamma-T3, without racemization at C-2 in rats.
Object Finding in Cluttered Scenes Using Interactive Perception (2019)

Object finding in clutter is a skill that requires perception of the environment and in many cases physical interaction. In robotics, interactive perception defines a set of algorithms that leverage actions to improve the perception of the environment, and vice versa use perception to guide the next action. Scene interactions are difficult to model, therefore, most of the current systems use predefined heuristics. This limits their ability to efficiently search for the target object in a complex environment. In order to remove heuristics and the need for explicit models of the interactions, in this work we propose a reinforcement learning based active and interactive perception system for scene exploration and object search. We evaluate our work both in simulated and in real-world experiments using a robotic manipulator equipped with an RGB and a depth camera, and compare our system to two baselines. The results indicate that our approach, trained in simulation only, transfers smoothly to reality and can solve the object finding task efficiently and with more than 88% success rate.
Adenosine receptor antagonists improve short-term object-recognition ability of spontaneously hypertensive rats: a rodent model of attention-deficit hyperactivity disorder (2009)

The strain of spontaneously hypertensive rats (SHR) is considered a genetic model for the study of attention-deficit hyperactivity disorder (ADHD), as it displays hyperactivity, impulsivity and poorly sustained attention. Recently, we have shown the involvement of adenosinergic neuromodulation in the SHR's short-term and long-term memory impairments. In this study, we investigated the performance of male and female SHR in a modified version of the object-recognition task (using objects with different structural complexity) and compared them with Wistar rats, a widely used outbred rat strain for the investigation of learning processes. The suitability of the SHR strain to represent an animal model of ADHD, as far as mnemonic deficits are concerned, was pharmacologically validated by the administration of methylphenidate, the first-choice drug for the treatment of ADHD patients. The role of adenosine A1 and A2A receptors in object discrimination was investigated by the administration of caffeine (nonselective antagonist) or selective adenosine receptor antagonists. Wistar rats discriminated all the objects used (cube vs. pyramid; cube vs. T-shaped object), whereas SHR only discriminated the most structurally distinct pairs of objects (cube vs. pyramid). Pretraining administration of methylphenidate [2 mg/kg, intraperitoneal (i.p.)], caffeine (1-10 mg/kg, i.p.), the selective adenosine receptor antagonists DPCPX (8-cyclopenthyl-1,3-dipropylxanthine; A1 antagonist, 5 mg/kg, i.p.) and ZM241385 (A2A antagonist, 1.0 mg/kg, i.p.), or the association of ineffective doses of DPCPX (3 mg/kg) and ZM241385 (0.5 mg/kg), improved the performance of SHR in the object-recognition task. These findings show that the discriminative learning impairments of SHR can be attenuated by the blockade of either A1 or A2A adenosine receptors, suggesting that adenosinergic antagonists might represent potentially interesting drugs for the treatment of ADHD.
An intensely sweet analog of kynurenine: 3-(4-chloroanthraniloyl)-DL-alanine (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAn intensely sweet analog of kynurenine: 3-(4-chloroanthraniloyl)-DL-alanineKeisuke Kawashima, Hiroshi Itoh, Naoto Yoneda, Katsuaki Hagio, Tamon Moriya, and Ichiro ChibataCite this: J. Agric. Food Chem. 1980, 28, 6, 1338–1340Publication Date (Print):November 1, 1980Publication History Published online1 May 2002Published inissue 1 November 1980https://pubs.acs.org/doi/10.1021/jf60232a078https://doi.org/10.1021/jf60232a078research-articleACS PublicationsRequest reuse permissionsArticle Views69Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Adhesive Specificity of the Soluble Human Lectin, IgE-Binding Protein, toward Lipid-Linked Oligosaccharides. Presence of the Blood Group A, B, B-like, and H Monosaccharides Confers a Binding Activity to Tetrasaccharide (Lacto-N-tetraose and Lacto-N-neotetraose) Backbones (1994)

The immunoglobulin E-binding protein, epsilon BP (also known as CBP35, Mac-2, L-34, and L-29), is a beta-galactoside-binding protein of approximately 30 kDa and a member of the animal lectin family termed S-type or S-Lac. Multiple biological activities have been attributed to this lectin such as mediation of IgE binding to the surface of Langerhans cells and activation of mast cells through binding to the high affinity IgE receptor. In order to better understand the cell-binding activity and the proposed role for epsilon BP as a biological response modifier, we have studied the specificity of binding of the radioiodinated epsilon BP to a series of lipid-linked, structurally defined oligosaccharide sequences of the lacto/neolacto family. The results show that the minimum lipid-linked oligosaccharides that can support epsilon BP binding are pentasaccharides of the lacto/neolacto series and that the lectin binds more strongly to oligosaccharides of this family that bear the blood group A, B, or B-like determinants than to those bearing blood group H. This preferential binding of epsilon BP is also manifest with whole cells, as erythrocytes of blood groups A and B are more strongly bound by epsilon BP than those of blood group O. Blood group Le(a) and Le(x) sequences are not bound by the lectin.(ABSTRACT TRUNCATED AT 250 WORDS)
Botulinum toxin A in the treatment of headache syndromes and pericranial pain syndromes (2001)

Göbel, Hartmut; Heinze, Axel; Heinze-Kuhn, Katja; Austermann, Kristina Author Information
Identification and Expression of Genes Involved in the Conversion of Daidzein and Genistein by the Equol-Forming Bacterium Slackia isoflavoniconvertens (2013)

Gut bacteria play a key role in the metabolism of dietary isoflavones, thereby influencing the availability and bioactivation of these polyphenols in the intestine. The human intestinal bacterium Slackia isoflavoniconvertens converts the main soybean isoflavones daidzein and genistein to equol and 5-hydroxy-equol, respectively. Cell extracts of S. isoflavoniconvertens catalyzed the conversion of daidzein via dihydrodaidzein to equol and that of genistein to dihydrogenistein. Growth of S. isoflavoniconvertens in the presence of daidzein led to the induction of several proteins as observed by two-dimensional difference gel electrophoresis. Based on determined peptide sequences, we identified a cluster of eight genes encoding the daidzein-induced proteins. Heterologous expression of three of these genes in Escherichia coli and enzyme activity tests with the resulting cell extracts identified the corresponding gene products as a daidzein reductase (DZNR), a dihydrodaidzein reductase (DHDR), and a tetrahydrodaidzein reductase (THDR). The recombinant DZNR also converted genistein to dihydrogenistein at higher rates than were observed for the conversion of daidzein to dihydrodaidzein. Higher rates were also observed with cell extracts of S. isoflavoniconvertens. The recombinant DHDR and THDR catalyzed the reduction of dihydrodaidzein to equol, while the corresponding conversion of dihydrogenistein to 5-hydroxy-equol was not observed. The DZNR, DHDR, and THDR were expressed as Strep-tag fusion proteins and subsequently purified by affinity chromatography. The purified enzymes were further characterized with regard to their activity, stereochemistry, quaternary structure, and content of flavin cofactors.
Complex integrated circuit design strategy (1982)

Presents a design strategy for VLSI circuits based on the use of a floor plan as an evaluation and management guide for the design of a future circuit. This approach is widely used in the microelectronic industry and allows global optimizations, which are the key to both high density and design reliability, by improving the assembly and the direct wiring of the blocks. The efficiency of such an approach may be improved by the use of a topological evaluator. This tool will give an evaluation of the shape, size, and connections of the main blocks from their specifications. It is able to take into account the topological constraints given by the designer in order to improve the assembly and connectivity of the floor plan. This tool is composed of a set of evaluation routines for the different kinds of functional blocks constituting a VLSI circuit and a supervisor for dialogue with the user.
THYMUS TRANSPLANTATION AFTER ALLOGENEIC BONE MARROW GRAFT TO PREVENT CHRONIC GRAFT-VERSUS-HOST DISEASE IN HUMANS (1982)

ATKINSON, KERRY; STORB, RAINER; OCHS, HANS D.; GOEHLE, SONDRA; SULLIVAN, KEITH M.; WITHERSPOON, ROBERT P.; LUM, LAWRENCE G.; TSOI, MANG-SO; SANDERS, JEAN E.; PARR, MARLENE; STEWART, PATRICIA; THOMAS, E. DONNALL Author Information
Effects of Fruit Ellagitannin Extracts, Ellagic Acid, and Their Colonic Metabolite, Urolithin A, on Wnt Signaling (2009)

Recent data suggest that ellagitannins (ETs), a class of hydrolyzable tannins found in some fruits and nuts, may have beneficial effects against colon cancer. In the stomach and gut, ETs hydrolyze to release ellagic acid (EA) and are converted by gut microbiota to urolithin A (UA; 3,8-dihydroxy-6H-dibenzopyran-6-one) type metabolites, which may persist in the colon through enterohepatic circulation. However, little is known about the mechanisms of action of either the native compounds or their metabolites on colon carcinogenesis. Components of Wnt signaling pathways are known to play a pivotal role in human colon carcinogenesis, and inappropriate activation of the signaling cascade is observed in 90% of colorectal cancers. This study investigated the effects of UA, EA, and ET-rich fruit extracts on Wnt signaling in a human 293T cell line using a luciferase reporter of canonical Wnt pathway-mediated transcriptional activation. The ET extracts were obtained from strawberry (Fragaria annassa), Jamun berry (Eugenia jambolana), and pomegranate (Punica granatum) fruit and were all standardized to phenolic content (as gallic acid equivalents, GAEs, by the Folin-Ciocalteu method) and to EA content (by high-performance liquid chromatography methods): strawberry = 20.5% GAE, 5.0% EA; Jamun berry = 20.5% GAE, 4.2% EA; pomegranate = 55% GAE, 3.5% EA. The ET extracts (IC(50) = 28.0-30.0 microg/mL), EA (IC(50) = 19.0 microg/mL; 63 microM), and UA (IC(50) = 9.0 microg/mL; 39 microM) inhibited Wnt signaling, suggesting that ET-rich foods have potential against colon carcinogenesis and that urolithins are relevant bioactive constituents in the colon.
p53 Expression: Predicting Recurrence and Second Primary Tumors in Head and Neck Squamous Cell Carcinoma (1996)

The expression of p53 protein in primary head and neck squamous cell carcinoma was significantly predictive of shorter survival because of its association with earlier development of both tumor recurrence and second primary tumors. Thus, p53 expression may be a valuable marker for identifying individuals at high risk of developing a recurrence of primary disease and second primary tumors who may benefit from adjuvant therapy and chemoprevention after definitive local therapy.
The Patterning of Work Meanings which are Coterminous with Work Outcome Levels for Individuals in Japan, Germany and the USA (1990)

L'analyse des données relatives à la signification du travail fournies par des échantillons représentatifs des travailleurs allemands, japonais et américains montre qu'il existe une relation étroite entre les modèles individuals de signification du travail et les scores sur des variables dépendantes générale‐ment considérées comme importantes pour l'individu (le revenu, la qualité du travail, la satisfaction professionnelle et la satisfaction liée au poste). On fait l'hypothèse que ces résultats convaincants s'observent en raison des “effets cohésifs” de certains modèles de signification du travail sur la “mobilisation motivationnelle” qui elle‐même influence les niveaux de performances. Selon ce type de raisonnement, les significations du travail sont des dimensions cognitives de la personnalité en rapport avec les niveaux de performances à travers leurs effets sur la motivation. Une possibilité de causalité réciproque entre personnalité et performance est mentionnée et on souligne la nécessité d‘étudier plus avant la raison de cette relation étroite. Analysis of work meaning data from representative national labour force samples in Germany, Japan, and the United States shows that there is a strong contingency between work meaning pattern membership of individuals and levels of outcome realisation on outcomes generally considered important to the individual (income, quality of work, occupational satisfaction, and job satisfaction). These strong findings are hypothesised to occur because of the “cohesive effects” of certain meaning of working patterns on “effort outlay” which in turn influences the level of outcome(s). This line of reasoning sees work meanings as personality constructs which are related to outcome levels through their effects on effort outlay. The possibility of reciprocal causation occurring between work personality and work outcomes is noted and the need to study further the causality of this strong contingency is highlighted.
Absorption kinetics of misoprostol with oral or vaginal administration (1997)

There are significant differences in the pharmacokinetics of misoprostol administered by vaginal and oral routes that may explain the difference observed in clinical efficacy. Assuming that the pharmacologic effect of misoprostol is related to its concentration in the plasma, our observation of the prolonged serum concentrations in the vaginal group suggests that vaginal administration could be dosed at longer intervals than oral.
Retinal-Image Quality and Contrast-Sensitivity Function in Age-Related Macular Degeneration (2010)

Patients affected with ARMD showed poorer retinal-image quality and visual performance than normal subjects. The use of objective devices based on the double-pass technique could be useful for the accurate description of the retinal-image quality of ARMD eyes, in which retinal scattering is significantly increased.
Precancer and cancer in extensive ulcerative colitis: findings among 401 patients over 22 years. (1990)

Patients with extensive ulcerative colitis who do not need early surgery have been offered regular examination with the aim of detecting precancerous change (dysplasia) or early colorectal carcinoma. Outpatient visits with clinical examination, sigmoidoscopy, and biopsy were supplemented by two-yearly colonoscopy after the disease course reached 10 years. During the 22 year period from the beginning of 1966 to the end of 1987, 401 patients entered the programme and together contributed 4048 patient-years of observation. Apart from nine patients who left the country, follow up is complete until 1986 or 1987. Colorectal carcinoma developed in 22 patients and, in a further 12, biopsy evidence of precancer, described as severe/high grade dysplasia, was confirmed in a colectomy specimen. The cumulative probability of developing carcinoma was 3% at 15 years, 5% at 20 years, and 9% at 25 years; corresponding figures for precancer or carcinoma, or both were 4%, 7%, and 13%. Five patients died of colorectal carcinoma, two while under regular observation and three after developing carcinoma four to six years after their last attendance. Among the 17 patients who developed carcinoma while under observation, the Dukes stage was A or B in 12. Patients with extensive colitis whose disability does not warrant early surgery have a clinically important cancer risk after the disease has been present for 10 years. Our results suggest that follow up in the manner described reduces the mortality from this complication. Further work is needed to define the optimum method of surveillance and show if it is cost effective.
Highway traffic state estimation using improved mixture kalman filters for effective ramp metering control (2004)

In this paper, we use a cell transmission model based switching state-space model to estimate vehicle densities and congestion modes at unmeasured locations on a highway section. The mixture Kalman filter algorithm, which is based on sequential Monte Carlo method, is employed to approximately solve the difficult problem of inference on a switching state-space model with an unobserved discrete state. We propose a scheme to prevent the risk of weight underflow and to introduce forgetting. The estimation results show that comparable accuracies can be achieved using either a small or a large number of sampling sequences, thus make it possible to carry out efficient online filtering. Underflow prevention and forgetting improves estimation accuracy in our examples. On average, a mean percentage error of approximately 10% is achieved for the vehicle density estimation. The estimation performance is consistent with data sets from various days.
On the Oriented Coloring of Honeycomb Graphs (2019)

In this paper, we focus on the oriented coloring of a graph G. Oriented coloring is a coloring of the vertices of an oriented graph H such that (1) no two neighbors in H are assigned in the same color, and (2) for every two arcs u→v and x→y, if v and x are assigned the same color then u and y cannot be assigned the same color. The oriented chromatic number of a graph G is the maximum oriented chromatic number over all possible orientations of G. In this paper, we derive a lower bound and an upper bound on the oriented chromatic number of honeycomb rectangular tori. Finally, we conjecture to the oriented chromatic number of honeycomb rectangular tori is 10.
SYNTHETIC VISION SYSTEM CALIBRATION FOR CONFORM PROJECTION ON THE PILOT’S HEAD-UP DISPLAY (2020)

Abstract. Situational awareness of the crew is critical for the safety of the air flight. Head-up display allows providing all required flight information in front of the pilot over the cockpit view visible through the cockpit’s front window. This device has been created for solving the problem of informational overload during piloting of an aircraft. While computer graphics such as scales and digital terrain model can be easily presented on the such display, errors in the Head-up display alignment for correct presenting of sensor data pose challenges. The main problem arises from the parallax between the pilot’s eyes and the position of the camera. This paper is focused on the development of an online calibration algorithm for conform projection of the 3D terrain and runway models on the pilot’s head-up display. The aim of our algorithm is to align the objects visible through the cockpit glass with their projections on the Head-up display. To improve the projection accuracy, we use an additional optical sensor installed on the aircraft. We combine classical photogrammetric techniques with modern deep learning approaches. Specifically, we use an object detection neural network model to find the runway area and align runway projection with its actual location. Secondly, we re-project the sensor’s image onto the 3D model of the terrain to eliminate errors caused by the parallax. We developed an environment simulator to evaluate our algorithm. Using the simulator we prepared a large training dataset. The dataset includes 2000 images of video sequences representing aircraft’s motion during takeoff, landing and taxi. The results of the evaluation are encouraging and demonstrate both qualitatively and quantitatively that the proposed algorithm is capable of precise alignment of the 3D models projected on a Head-up display.