gebhart/patrepeval huggingface dataset:
Speech feature extracted from adaptive wavelet forspeech recognition (1998)

A new speech feature extracted from adaptive wavelet for speech recognition is described. The speech signal is decomposed through adapted local trigonometric transforms. The decomposed signal is classified by M uniform sub-bands for each subinterval. The energy of each sub-band is used as a speech feature. This feature is applied to vector quantisation and the hidden Markov model. The new speech feature shows a slightly better recognition rate than the cepstrum for speaker independent speech recognition. The new speech feature also shows a lower standard deviation between speakers than does the cepstrum.
Calibration of Oxygen-Dependent Quenching of the Phosphorescence of Pd-meso-tetra (4-Carboxyphenyl) Porphine: A Phosphor with General Application for Measuring Oxygen Concentration in Biological Systems (1996)

Oxygen-dependent quenching of phosphorescence is a function of the frequency of collision between the phosphor and molecular oxygen and of the efficiency of energy transfer during these collisions. Thus, quenching is dependent on the rate of diffusion of the phosphor and its molecular environment. For measurements in biological samples, the Pd-porphyrin is bound to serum albumin, and this provides a uniform microenvironment for the phosphor which is relatively unaffected by changes in the pH and ionic composition of the medium. Calibration of the phosphor is of particular value because it is absolute, i.e., the calibration is valid independent of the laboratory and the time of measurement. This paper reports the calibration constants determined for Pd-meso-tetra (4-carboxyphenyl) porphine, as measured by two independent methods: by stoichiometric titration of the oxygen with ascorbate in the presence of ascorbate oxidase and by comparison with a high-accuracy oxygen electrode. The measurements were carried out in a specially designed thermostatted vessel in which the oxygen electrode and phosphorescence lifetime measurements of oxygen were made simultaneously. The calibration constants for the oxygen-dependent quenching of the phosphorescence of Pd-meso-tetra (4-carboxyphenyl) porphine were determined as a function of albumin concentration, ionic strength in medium, pH, and temperature.
IMC: A communication protocol for networked vehicles and sensors (2009)

This paper presents the Inter-Module Communication (IMC) protocol, a message-oriented protocol designed and implemented in the Underwater Systems and Technology Laboratory (LSTS) to build interconnected systems of vehicles, sensors and human operators that are able to pursue common goals cooperatively by exchanging real-time information about the environment and updated objectives. IMC abstracts hardware and communication heterogeniety by providing a shared set of messages that can be serialized and transferred over different means.
Randomized trial of aloe vera gel vs triamcinolone acetonide ointment in the treatment of oral lichen planus. (2012)

Aloe vera gel can be considered a safe alternative treatment for oral lichen planus.
Identification of anti-HIV and anti-Reverse Transcriptase activity from Tetracera scandens (2012)

We report here that an ethanol extract of Tetracera scandens, a Vietnamese medicinal plant, has anti-HIV activity and possesses strong inhibitory activity against HIV-1 reverse transcriptase (RTase). Using a MT-4 cell-based assay, we found that the T. scandens extract inhibited effectively HIV virus replication with an IC(50) value in the range of 2.0-2.5 μg/ml while the cellular toxicity value (CC50) was more than 40-50 μg/ml concentration, thus yielding a minimum specificity index of 20-fold. Moreover, the anti-HIV efficacy of the T. scandens extract was determined to be due, in part, to its potent inhibitory activity against HIV-1 RTase activity in vitro. The inhibitory activity against the RTase was further confirmed by probing viral cDNA production, an intermediate of viral reverse transcription, in virus-infected cells using quantitative DNA-PCR analysis. Thus, these results suggest that T. scandens can be a useful source for the isolation and development of new anti- HIV-1 inhibitor(s). [BMB reports 2012; 45(3): 165-170].
Methylation-Specific MLPA (MS-MLPA): simultaneous detection of CpG methylation and copy number changes of up to 40 sequences (2005)

Copy number changes and CpG methylation of various genes are hallmarks of tumor development but are not yet widely used in diagnostic settings. The recently developed multiplex ligation-dependent probe amplification (MLPA) method has increased the possibilities for multiplex detection of gene copy number aberrations in a routine laboratory. Here we describe a novel robust method: the methylation-specific MLPA (MS-MLPA) that can detect changes in both CpG methylation as well as copy number of up to 40 chromosomal sequences in a simple reaction. In MS-MLPA, the ligation of MLPA probe oligonucleotides is combined with digestion of the genomic DNA-probe hybrid complexes with methylation-sensitive endonucleases. Digestion of the genomic DNA-probe complex, rather than double-stranded genomic DNA, allowed the use of DNA derived from the formalin treated paraffin-embedded tissue samples, enabling retrospective studies. To validate this novel method, we used MS-MLPA to detect aberrant methylation in DNA samples of patients with Prader-Willy syndrome, Angelman syndrome or acute myeloid leukemia.
La pregunta parlamentaria: ¿Regulación o Reforma? (2016)

A raiz de las reformas a los articulos 69 y 93 constitucionales de 2008 que sustentaron el nuevo formato para el Informe Presidencial, los senadores y diputados de esta LXI Legislatura tuvieron ocasion, como lo habian  hecho los de la LX, de formular observaciones, cuestionamientos y solicitudes de informacion complementaria  al titular del Ejecutivo, con base en la pregunta parlamentaria, figura que se constituyo en parte central  de esa reforma; en esta oportunidad, con motivo del tercer Informe de Gobierno.   En lo que toca a las preguntas formuladas por senadores de diferentes fracciones y a las respuestas obtenidas, resulto evidente a la luz del analisis de unas y otras, que aquel instrumento constitucional no ha logrado aprovecharse en todo su potencial para avanzar en los objetivos que se propuso: abonar en una efectiva rendicion de cuentas; fortalecer la cooperacion y comunicacion entre poderes, y fungir como efectivo mecanismo de control de los actos del Ejecutivo por parte del Congreso y, sobre todo, su utilidad relativa, a menos que sea complementado con otros mecanismos pendientes de diseno e implementacion. La razon principal radica en que hasta hoy la pregunta parlamentaria no ha logrado reglamentarse en la legislacion secundaria y, derivado de ello, en el hecho de que los acuerdos parlamentarios emitidos para suplir, aun provisionalmente ese vacio juridico, no solo han resultado insuficientemente funcionales para una  implementacion adecuada de esa figura sino, incluso, inconsistentes con el espiritu de la reforma. A ello se debe que buena parte de las preguntas y las respuestas continuen reproduciendo, en los hechos, practicas anejas que buscaban desterrarse: informacion sesgada o incompleta, opacidad, comunicacion deficiente y obstaculizacion de acuerdos.   Puede senalarse, en sintesis, que los resultados hasta hoy logrados desde la vigencia de esas reformas constitucionales, estan lejos de corresponder a los esfuerzos que posibilitaron el consenso para garantizar rango constitucional a la pregunta parlamentaria y apartados todavia de los fines que con ello se pretendia.  En los siguientes apartados se da cuenta sucinta de ello.
Synthesis and pharmacological properties of 6-substituted 3-(pyridine-4-yl)-1,2,4-triazole [3,4-b][1,3,4]thiadiazoles. (1991)

A number of new 6-substituted 3-(pyridine-4-yl) 1,2,4-triazole[3,4-b][1,3,4]thiadiazoles were synthesized and evaluated for their pharmacological activity. Some of them exhibited moderate MAO, antimalarial and in vitro antitumor activity.
Cross Section and Critical Dimension Metrology in Dense High Aspect Ratio Patterns with CD-SAXS (2005)

The continuing progress of sub‐65 nm patterning technologies highlights the critical need for high precision metrologies capable of characterizing dense, high aspect ratio patterns. We present data from small angle x‐ray scattering measurements of critical dimension and average pattern cross section of photoresist line/space patterns. The technique is non‐destructive and capable of sub‐nm precision in characterizing dimensions and sub‐degree precision in sidewall angle of patterns with regular periodicity. Moreover, the information enabling linewidth, pitch and sidewall angle determination are decoupled. Efforts to probe line edge roughness are also discussed. The technique is applicable to dense structures of arbitrary composition with dimensions of (10 to 500) nm, including lines, vias and contact holes and buried structures.
Case 48-1993 (1993)

Presentation of CaseA 27-year-old woman was admitted to the hospital because of pulmonary hypertension with increasing right-sided heart failure.The patient had been well and active until nine months earlier, when she first experienced mild dyspnea while riding a bicycle. The dyspnea worsened, and three months before entry medical evaluation elsewhere included radiographs of the chest that showed slight cardiac enlargement and prominent pulmonary-artery shadows. An ultrasonographic examination of the heart revealed marked dilatation of the right ventricle, with moderate tricuspid regurgitation; the estimated pulmonary arterial pressure was over 100 mm Hg. A ventilation-perfusion scan disclosed no evidence of . . .
Egg Production of Chickens Kept in Darkness (1958)

ALTHOUGH darkness allegedly inhibits egg production, our previous work (Wilson and Abplanalp, 1956) showed that pullets would lay eggs with a daily ration of six minutes of light in 24 hours. Rearing pullets in darkness does not prevent them from coming into egg production according to Rider (1938). Continuous darkness actually produced maximum testicular weight in the parakeet, Melapsittacus undulatus, in the experiments of Vaugien (1953). The purpose of these tests was to determine the length of time hens would remain in production when subjected to complete darkness. EXPERIMENTAL Two tests were made in which S. C. White Leghorn laying hens in cages spent a 5-week period in complete darkness. The first test was with 60 hens kept in three separate pens of 20 hens each. From 17 to 38 weeks of age these hens had been given alternately two hours of light and two hours of darkness. They had . . .
Oracle-Guided Incremental SAT Solving to Reverse Engineer Camouflaged Logic Circuits (2016)

Layout-level gate camouflaging has attracted interest as a countermeasure against reverse engineering of combinational logic. In order to minimize area overhead, typically only a subset of gates in a circuit are camouflaged, and each camouflaged gate layout can implement a few different logic functions. The security of camouflaging relies on the difficulty of learning the overall combinational logic function without knowing which logic functions the camouflaged gates implement.
The kinematic analysis and stiffness optimization for an 8-DOF cable-driven manipulator (2017)

This paper proposed an 8-degrees-of-freedom (8-DOF) cable-driven robotic arm (CDRA) composed of four identical 2-DOF cable-driven joints with variable stiffness. The proposed cable-driven joints are equipped with variable stiffness devices to increase the stiffness adjustable range. Therefore, an inverse displacement algorithm is proposed for this redundant robotic arm using the conjugate gradient method. A rotation control function is employed as an objective to minimize due to the character that the cable-driven joints has a larger stiffness range when the joint angle is small. With such algorithm, the joint angles will have a larger stiffness range. Then, the stiffness of the CDRA is analyzed with the body manipulator Jacobian employed. An optimization algorithm using similar conjugate gradient method is proposed to obtain the desired stiffness. Low cable tension level could be obtained with a "tension level index" employed in the optimization. A simulation of the algorithm is conducted and the result shows that such method is effective and computational efficient.
Diagnosis of Helicobacter pylori infection by PCR: comparison with other invasive techniques and detection of cagA gene in gastric biopsy specimens (1995)

A PCR assay for the detection of Helicobacter pylori in gastric biopsy specimens with specific primers for ureC gene amplification (herein referred to as ureC PCR) was compared with other routine invasive methods (culture, the rapid-urease test, and Giemsa staining of histological sections) with samples from a group of 104 consecutive dyspeptic patients. Bacteria were found in 40 (38.5%), 38 (36.5%), 36 (34.6%), and 35 (33.7%) of the patients by ureC PCR, culture, the rapid-urease test, and Giemsa stain, respectively. Sixty-three patients had negative cultures, negative histological examinations, and negative rapid-urease test results, and 61 of these patients were also negative by ureC PCR. ureC PCR detected H. pylori in two culture-negative patients. In parallel, a PCR-based assay to detect the H. pylori cytotoxin-associated antigen (cagA) gene, a putative virulence gene, was also developed. To assess the likelihood of detection of H. pylori genes directly from gastric biopsy samples and from the corresponding H. pylori isolates, specimens from 31 patients were subjected to PCR with ureC- and cagA-targeting primers. All 31 biopsy specimens and the corresponding H. pylori isolates were positive in the ureC PCR. H. pylori strains that were cagA positive also gave positive cagA PCR fragments with biopsy specimens from the same patients. All ureC PCR-positive patients were examined; biopsy specimens from 10 of 11 (91.7%) duodenal ulcer patients harbored H. pylori cagA-positive strains, whereas 19 of26 (73%) of those from patients with chronic gastritis only were found to be cagA positive. These findings indicate first that ureC PCR is at least as sensitive as culture for diagnosing H. pylori infection and second that the presence of the H. pylori cagA gene can also be detected directly in biopsy specimens by PCR amplification.
Damping Associated with Incipient Melting in Aluminum-Indium Alloys (1990)

Abstract : The strain amplitude dependent damping of binary aluminum-indium alloys containing nominally 0.6 to 17.3 weight percent indium was studied. A dynamic mechanical analyzer was used to measure the damping capacity of these materials. Pure aluminum (99.99%) exhibited strain dependent damping at strain values as low as 70 microstrain. The addition of 0.6 weight percent indium reduced the strain dependent damping by a factor of 2, but the strain dependent damping was equivalent to that of pure aluminum. Binary aluminum-indium alloys containing 4, 8, 12 and 16 weight percent indium exhibited a general increase in loss factor with increasing indium content; however, the strain dependent damping was no greater than that of the pure aluminum sample. No significant increase in damping was observed when the binary alloys were tested at temperatures above the melting point of indium. Two damping peaks were observed near the eutectic melting point when tested at 10 Hz and differential scanning calorimetry verified both of these as due to the melting of the indium inclusions. It was concluded that the higher temperature damping peak was associated with smaller indium inclusions and that the damping peaks were related to the solute segregation associated with the binary eutectic reaction. (aw)
Corrosion of Metals by Insecticidal Solutions (1950)

The purpose of this investigation was to determine the comparative corrosion resistance of stainless steel, copper, brass, aluminum, magnesium alloy, aluminum alloy, cold rolled steel, and galvanized iron when immersed in various insecticide solutions. The eight metals were immersed in fourteen test solutions for eight weeks and periodic observations were made to determine the extent of corrosion. Weight loss and pitting, as a result of the eight-week immersion, were also determined. It is concluded that: DDT in water displays a definite tendency to inhibit corrosion;2-4-D inhibited corrosion on all metals tested;Chlorodane is a corrosive acid insecticide;Insecticides in kerosene or a fuel oil base are not corrosive;The most corrosive insecticide solutions are chlorodane in water, sodium arsenite in water, and DDT in salt water;Stainless steel is the only completely corrosionresistant metal;Aluminum is of satisfactory corrosion resistance in all of the solutions except sodium arsenite. It is recommended that aluminum, aluminum alloys, and Alclad, both with and without a corrosion inhibiting pretreatment such as anodizing, be investigated for their corrosion resistance to chlorodane in water, sodium arsenite in water, and DDT in salt water.
Implementing basic image processing programs onto a linearly connected parallel processor (2010)

In many image processing systems, an input grayscale image is reformed to make a clear image. After this reformation, the obtained gray-scale image is transformed into a binary image. Some gray-scale and binary image processing programs are implemented onto a linearly connected parallel processor. After partitioning an image into rectangular regions, each region is loaded in the main memory of a processing element (PE) as a partial image of the input image. PE's are connected through two communication memories. By accessing different memories, it accesses pixels stored on adjacent PE's without conflicts of memory access. In spite of the simple architecture of this linearly connected parallel processor, the results of the implementation of some programs indicate that execution times are improved, depending on the number of PE's.
A motion-compensated spatio-temporal filter for image sequences with signal-dependent noise (1998)

A novel spatio-temporal filter is described for monochrome image sequences with either signal-independent or signal-dependent noise by considering both spatial and temporal correlations. With the assumptions of spatio-temporal separability and temporal stationarity, it is shown that motion-compensated groups of frames can be decorrelated by using the Karhunen-Loeve transform. Practical filters that work well on a variety of image sequences are developed by first applying the Hadamard transform along the temporal direction. Subsequently, the parametric adaptive Wiener filter is applied to each of the resulting approximately decorrelated transformed images. These transformed images are classified into one average image and a remaining set of residual images, which provide interesting and useful interpretations of the type of image sequence. The filter performance is evaluated by considering different types of image sequences in the database. The procedure advanced for processing a sequence of monochrome images can be adapted for generalization to multispectral images and this possibility is currently under detailed investigation.
Prognostic Significance of Tumor Necrosis in Primary Transitional Cell Carcinoma of Upper Urinary Tract (2007)

Our results suggest that macroscopic tumor necrosis may be a useful prognostic indicator for primary TCC of upper urinary, especially for invasive tumors. Further investigation would be warranted for the prognostic implications of tumor necrosis in TCCs of upper urinary tract and on actual pathogenesis of tumor necrosis in upper tract TCC.
Decrease in equilibrative uridine transport during monocytic differentiation of HL-60 leukaemia: involvement of protein kinase C (1994)

The dose-response curves for the inhibition of equilibrative uridine transport by dilazep, dipyridamole and nitrobenzylthioinosine (NBMPR) in undifferentiated HL-60 cells were biphasic. Some 70% of the transport activity was inhibited with IC50 values of 0.7, 1 and 7 nM respectively. No inhibition of the remaining 30% of transport activity was observed until the dilazep, dipyridamole and NBMPR concentrations exceeded 1, 0.1 and 3 microM respectively. Exposure to phorbol 12-myristate 13-acetate (PMA) for 48 h, to induce monocytic differentiation, caused a 20-fold decrease in Vmax. of both NBMPR-sensitive and NBMPR-insensitive equilibrative uridine transport. The decrease in NBMPR-sensitive uridine transport induced by PMA corresponded to a decrease in NBMPR binding sites. A 30% decrease in specific NBMPR binding sites occurred within 6 h of PMA exposure, and could be prevented by uridine and thymidine at concentrations as low as 100 microM, and by staurosporine at 40 nM. However, the protective effects of these compounds diminished with prolonged PMA exposure. No protection was observed with uracil. Exogenous protein kinase C (PKC) in the presence of ATP and PMA decreased the number of specific NBMPR-binding sites in purified HL-60 cell plasma membranes. These results suggest that a PKC-induced conformational change in substrate-binding/transporting site may be responsible for the decrease in NBMPR-sensitive nucleoside transport during PMA-induced monocytic differentiation of HL-60 cells.
AAV Gene Therapy for MPS1-associated Corneal Blindness (2016)

Although cord blood transplantation has significantly extended the lifespan of mucopolysaccharidosis type 1 (MPS1) patients, over 95% manifest cornea clouding with about 50% progressing to blindness. As corneal transplants are met with high rejection rates in MPS1 children, there remains no treatment to prevent blindness or restore vision in MPS1 children. Since MPS1 is caused by mutations in idua, which encodes alpha-L-iduronidase, a gene addition strategy to prevent, and potentially reverse, MPS1-associated corneal blindness was investigated. Initially, a codon optimized idua cDNA expression cassette (opt-IDUA) was validated for IDUA production and function following adeno-associated virus (AAV) vector transduction of MPS1 patient fibroblasts. Then, an AAV serotype evaluation in human cornea explants identified an AAV8 and 9 chimeric capsid (8G9) as most efficient for transduction. AAV8G9-opt-IDUA administered to human corneas via intrastromal injection demonstrated widespread transduction, which included cells that naturally produce IDUA, and resulted in a >10-fold supraphysiological increase in IDUA activity. No significant apoptosis related to AAV vectors or IDUA was observed under any conditions in both human corneas and MPS1 patient fibroblasts. The collective preclinical data demonstrate safe and efficient IDUA delivery to human corneas, which may prevent and potentially reverse MPS1-associated cornea blindness.
DSP core with parallel module testability (2003)

A description is given of a custom-designed, 160 K-transistor TMS320C25 DSP (digital signal processor) core processor, which has been combined with a 5 K user-programmable gate array and built-in parallel module testability. The research vehicle, designed to analyze practical issues of embedded core DSPs and manufactured in a 1- mu m CMOS process, runs at a 50-MHz clock frequency in the DSP core and has a gate delay of 0.5 ns (FO=3) in the gate array. The parallel module test (PMT) methodology is used to obtain and effectively test the DSP core during manufacturing. The method introduces a minimum speed penalty, approximately one quarter of a nanosecond, under normal operation paths and requires only one dedicated TEST pin at the device package. The joint test action group PMT system architecture can also support board-level testing.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>