gebhart/patrepeval huggingface dataset:
A machine learning approach to pronoun resolution in spoken dialogue (2003)

We apply a decision tree based approach to pronoun resolution in spoken dialogue. Our system deals with pronouns with NPand non-NP-antecedents. We present a set of features designed for pronoun resolution in spoken dialogue and determine the most promising features. We evaluate the system on twenty Switchboard dialogues and show that it compares well to Byron's (2002) manually tuned system.
Bacterial Metabolism of <i>para</i> -and <i>meta</i> -Xylene: Oxidation of the Aromatic Ring (1974)

Pseudomonas putida 39/D oxidized p-xylene to cis-3,6-dimethyl-3,5-cyclohexadiene-1,2-diol (cis-p-xylene dihydrodiol). The latter compound was isolated in crystalline form and its physical properties were determined. The cis configuration of the hydroxyl groups in the oxidation product was inferred from its ability to form an isopropylidene derivative with 2,2-dimethoxypropane. Acid treatment of cis-p-xylene dihydrodiol resulted in the formation of 2,5-dimethylphenol. A partially purified preparation of cis-toluene dihydrodiol dehydrogenase oxidized cis-p-xylene dihydrodiol to 1,2-dihydroxy-3,6-dimethylbenzene (3,6-dimethylpyrocatechol). P. putida 39/D oxidized m-xylene to a compound whose spectral and chromatographic characteristics were consistent with the structure 3,5-dimethyl-3,5-cyclohexadiene-1,2-diol. This product was very unstable, and all attempts to isolate it led to the formation of 2,4-dimethylphenol.
Regional blood-brain barrier transport of cationized bovine serum albumin in awake rats (1991)

Regional blood-brain barrier permeability-surface area products (PAs) of cationized bovine serum albumin (cBSA) with isoelectric point (pI) approximately 8 or greater than or equal to 11 and of native bovine serum albumin (nBSA;pI approximately 4) were determined in awake male Sprague-Dawley rats after bolus intravenous injection. The albumins were labeled with 125I. Brain uptakes were assessed by autoradiography and by direct assay of radioactivity in brain regions. nBSA uptake into brain was statistically insignificant over 3 h, whereas cBSA uptake was significantly even at 6 min. Mean PA values of cBSA with pI approximately 11 (1.69-2.65 x 10(-5) ml.s-1.g-1) in most brain regions were twofold higher than PAs of cBSA with pI approximately 8 (0.98-1.37 x 10(-5) ml.s-1.g-1), whereas mean PA for nBSA did not differ significantly from zero. Autoradiographs of brain slices and net distributions in brain compartments at 6 and 30 min after injection suggested that cBSA entered the brain parenchyma via blood vessels and cerebrospinal fluid but that the former was the main route. The results quantitate for the first time regional brain PA values for cationized proteins and suggest specific mechanisms at cerebral blood vessels that distinguish transport of cationized from noncationized macromolecules.
Differential stability of mitochondrial mRNA in HeLa cells. (2005)

The physiological significance and metabolism of oligoadenylated and polyadenylated human mitochondrial mRNAs are not known to date. After study of eight mitochondrial transcripts (ND1, ND2, ND3, ND5, CO1, CO2, ATP6/8 and Cyt. b) we found a direct correlation between the half-lives of mitochondrial mRNAs and their steady-state levels. Investigation of the mt-mRNA decay after thiamphenicol treatment indicated that three transcripts (ND2, ND3 and Cyt. b) are significantly stabilized after inhibition of mitochondrial translation. Careful analysis one of them, ND3, showed that inaccurate processing of the H-strand RNA precursor may occasionally occur between the ND3 and tRNA(Arg) locus leading to synthesis of ND3 mRNAs lacking the STOP codon. However, analysis of the oligo(A) fraction observed in case of the ND3 indicates that partially polyadenylated mRNAs are linked rather to the transcription process than to the translation-dependent deadenylation. Analysis of ND3 mRNA turnover in cells with siRNA-mediated knock-down of the mitochondrial poly(A) polymerase shows that strongly decreased polyadenylation does not markedly affect the decay of this transcript. We present a model where oligoadenylated mitochondrial transcripts are precursors of molecules containing full length poly(A) tails.
High power lithium ion battery materials by computational design (2011)

Abstract Empirical bond length–bond valence (BV) relations provide insight into the link between structure of and ion transport in solid electrolytes and mixed conductors. Building on our earlier systematic adjustment of BV parameters to the bond softness, here we discuss how the squared BV mismatch is linked to the absolute energy scale and used as a general Morse‐type interaction potential for analyzing low‐energy ion migration paths in ion conducting solids or mixed conductors by either an energy landscape approach or molecular dynamics (MD) simulations. For a wide range of lithium oxides we could thus model ion transport revealing significant differences to an earlier geometric approach. This novel BV‐based force‐field has then been applied to investigate a range of mixed conductors, focusing on cathode materials for lithium ion battery (LIB) applications to promote a systematic design of LIB cathodes that combine high energy density with high power density. To demonstrate the versatility of the new BV‐based force field it is applied in exploring various strategies to enhance the power performance of safe low cost LIB materials including LiFePO 4 , LiVPO 4 F, LiFeSO 4 F, etc.
Characterization of carbon-doped InSb diode grown by molecular beam epitaxy (2007)

Carbon-doped p-type InSb layers grown by solid source molecular beam epitaxy are characterized using a p+–n diode structure. Based on the combination of current–voltage, secondary ion mass spectroscopy and x-ray diffraction measurements, carbon is proven to be an effective p-type dopant for InSb with hole concentration reaching the range of 1019 cm−3. It is also proven that the use of the Hall effect to determine the hole concentration in the p-type InSb layer may be unreliable in cases where the leakage current in the p+–n junction is high. A thermal trap-assisted tunnelling model with two trap levels successfully explains the origin of leakage current mechanisms in the carbon-doped InSb samples. Good agreement between measured and calculated dc characteristics of the diodes at reverse bias up to −3 V from 30 to 120 K supports the validity of the current transport model.
Characterization of genomic BCR‐ABL breakpoints in chronic myeloid leukaemia by PCR (1995)

In order to understand better the mechanism of translocation between the BCR and ABL genes in CML, we have exploited a 'bubble PCR' technique to clone genomic breakpoints. BCR-ABL junction fragments were successfully amplified and sequenced in 14/32 (43%) patients tested. Breakpoints were dispersed throughout the major breakpoint cluster region without any clustering or hot spots. In three cases Alu sequences were found at or near the breakpoint on the ABL side of the translocation but no other obvious sequence homologies were found either in BCR or ABL. The translocation event was characterized further in three other patients by amplifying the reciprocal ABL-BCR junction on the 9q+ chromosome and also normal ABL around breakpoints. In two of these patients a few nucleotides of BCR and ABL were either duplicated or deleted on translocation, suggesting that staggered cuts had been made in the DNA strand prior to recombination. In the third patient 50 bp of ABL was deleted and 159 bp of M-BCR including exon b3 was duplicated, indicating either that the single-stranded cuts may span a larger distance than previously thought or that another mechanism, perhaps involving gene conversion, may be involved in this instance.
Reviving National Muffler: Analyzing the Effect of Mayo Foundation on Judicial Deference as Applied to General Tax Authority Guidance (2012)

The Chevron decision cast doubt upon the viability of
Mechanisms of Discourse Comprehension Impairment After Right Hemisphere Brain Damage (2000)

Normal comprehension skill is linked with the proficiency of a suppression mechanism, which functions to dampen mental activation that becomes irrelevant or inappropriate to a final interpretation. This study investigated suppression and discourse comprehension in adults with right brain damage (RBD). To index suppression function, 40 adults with RBD and 40 without brain damage listened to sentence stimuli that biased the meaning of a sentence-final lexical ambiguity (e.g., SPADE), then judged whether a probe word (e.g., CARDS) fit the overall sentence meaning. Probes represented the contextually inappropriate meanings of the ambiguities and were presented in two conditions: 175 ms and 1000 ms post-stimulus. The same probes were used with unambiguous comparison stimuli. Probe judgment response times indicated that only the group without brain damage suppressed inappropriate interpretations over time. In a multiple regression analysis, suppression function added significantly to predicting performance on a general measure of narrative discourse comprehension for participants with RBD. The discussion addresses how suppression deficits may account more broadly for comprehension difficulties after RBD; it also considers several unresolved issues concerning the suppression construct and the suppression deficit hypothesis.
E.M. MWD Data Transmission Status and Perspectives (1993)

Abstract After 20 years of DHMWD the market is still demanding a tool which is discreet and can operate reliably whatever the status of the rig. The electromagnetic transmission overcomes its primary depth limitation and matchs drillers requirements: high reliability, no drilling contraints…, this paper summarises the technology status and points out the potential for future developments.
Control of multiple bandgap shifts in InGaAs-AlInGaAs multiple-quantum-well material using different thicknesses of PECVD SiO<sub>2</sub> protection layers (2000)

A useful development of the sputtered SiO/sub 2/ intermixing technique is reported, which uses a single stage of sputtered SiO/sub 2/ deposition and annealing to achieve precise tuning of the bandgap energy in the InGaAs-AlInGaAs material system. The blue shift of photoluminescence spectra can be varied in the range of 0-160 nm. Bandgap-tuned lasers were integrated on a single chip using this technique to assess the post-processed material characteristics and demonstrate its application in optoelectronic integration.
Transient Neurological Attacks in the General Population (1997)

About half of the subjects with a TNA had symptoms that were not entirely typical for a TIA. Differences in associations with risk factors between typical TIA and nonspecific TNA point toward different underlying mechanisms of symptoms and may lead to different ancillary investigations and possibly treatment.
Highly adjustable 3D nano-architectures and chemistries <i>via</i> assembled 1D biological templates (2018)

Porous metal nanofoams have made significant contributions to a diverse set of technologies from separation and filtration to aerospace. Nonetheless, finer control over nano and microscale features must be gained to reach the full potential of these materials in energy storage, catalytic, and sensing applications. As biologics naturally occur and assemble into nano and micro architectures, templating on assembled biological materials enables nanoscale architectural control without the limited chemical scope or specialized equipment inherent to alternative synthetic techniques. Here, we rationally assemble 1D biological templates into scalable, 3D structures to fabricate metal nanofoams with a variety of genetically programmable architectures and material chemistries. We demonstrate that nanofoam architecture can be modulated by manipulating viral assembly, specifically by editing the viral surface coat protein, as well as altering templating density. These architectures were retained over a broad range of compositions including monometallic and bi-metallic combinations of noble and transition metals of copper, nickel, cobalt, and gold. Phosphorous and boron incorporation was also explored. In addition to increasing the surface area over a factor of 50, as compared to the nanofoam's geometric footprint, this process also resulted in a decreased average crystal size and altered phase composition as compared to non-templated controls. Finally, templated hydrogels were deposited on the centimeter scale into an array of substrates as well as free standing foams, demonstrating the scalability and flexibility of this synthetic method towards device integration. As such, we anticipate that this method will provide a platform to better study the synergistic and de-coupled effects between nano-structure and composition for a variety of applications including energy storage, catalysis, and sensing.
Organic Photovoltaic Devices Based on a Novel Acceptor Material: Graphene (2008)

Solution-processable functionalized graphene (SPFGraphene, see figure) is used as the electron-accepting material in organic photovoltaic (OPV) devices for the first time, showing that it is a competitive alternative. The fabrication and performance of bulk heterojunction OPV devices with SPFGraphene and different donor materials is presented, together with the impact of post-fabrication annealing.
Human T-cell leukemia-lymphoma virus and adult T-cell leukemia (1983)

THE ISOLATION and characterization of the human T-cell leukemia-lymphoma virus (HTLV)<sup>1-5</sup>and its relationship to adult T-cell leukemia (ATL)<sup>6-8</sup>represent the remarkable convergence of scientific discoveries made half a world apart. The discovery of HTLV represents the culmination of a search for a true human retrovirus (type C virus) that dates back more than 50 years. Almost simultaneous to this breakthrough was the remarkable recognition of a distinctive clinicopathologic entity, ATL.<sup>9-11</sup>The molecular and clinical studies summarized in this review represent a scientific tale of two cities, Bethesda, Md, and Kyoto, Japan. <h3>HTLV: A Prototype Human Retrovirus</h3> In numerous animal species, naturally occurring leukemias or lymphomas are caused by retroviruses (also known as type C viruses, RNA tumor viruses, leukemia viruses).<sup>12-14</sup>This class of virus is characterized by a replication cycle requiring integration of the viral genetic material in the form of a provirus into host
In vivo imaging of zebrafish retinal cells using fluorescent coumarin derivatives (2010)

The coumarin derivatives identified in this study can stain zebrafish retinal cells in a relatively short time and at low concentrations, making them suitable for in vivo imaging of the zebrafish retina. Therefore, they will be useful tools in genetic and chemical screenings using zebrafish to identify genes and chemicals that may have crucial functions in the retina.
The monoclonal antibody MEL‐14 can block lymphocyte migration into a site ofchronic inflammation (1992)

The effect of MEL-14, a monoclonal antibody which binds to the lymphocyte homing receptor (MEL-14 Ag) on lymphocytes for peripheral lymph node (PLN) high endothelial venules (HEV), was investigated on lymphocyte migration into a delayed-type hypersensitivity (DTH)-like lesion produced by sensitization and challenge to Bordetella pertussis vaccine (BPV). Pretreatment of lymphocytes with saturating concentrations of MEL-14 caused a highly significant inhibition of lymphocyte migration into the chronically inflamed site and PLN. This finding suggests that lymphocyte migration into the BPV-induced site of chronic inflammation may be regulated by the same mechanism as lymphocyte migration into the PLN. It further indicates that the ligand for the MEL-14 Ag adhesion molecule, recognized by lymphocyte which home to the PLN, may also be expressed on HEV-like vessels at sites of BPV-induced chronic inflammation.
Self-assembly and phase behaviour of PEI : cationic surfactant aqueous mixtures forming mesostructured films at the air/solution interface (2013)

Self-assembly processes and corresponding phase boundaries depend on the structure of interacting molecules. We have studied the effect of surfactant head-group structure and counterion on the self-assembly processes occurring in aqueous mixtures of the cationic polymer polyethylenimine (PEI) and the cationic surfactants cetyltrimethylammonium bromide (CTAB), cetylpyridinium bromide (CPB) and cetylpyridinium chloride (CPC). Surface tension and conductometric methods were employed, as well as X-ray scattering and reflectometry techniques. The results indicate that the phase behaviour of PEI : cationic surfactant mixtures under dilute conditions can be tuned by altering head-group and counterion. The surfactant head-group exerts a greater influence overall, especially over micellization, since the counterion effect is screened at high polymer concentrations. Also, the self-assembly processes occurring at lower surfactant concentrations are not significantly affected by the counterion effect. The variation of surface tension with surfactant concentration shows a particular ‘well-like’ profile with a distinct break-point that can be directly related to the onset of film formation. Phase diagrams constructed using surface tension, conductivity and Brewster angle microscopy (BAM) data show three different regions where initial interactions, film formation and micellization take place, respectively, characterized by the two main self-assembly boundaries. Based on these results, we propose a molecular interpretation of the aggregation and film formation processes occurring in PEI : cationic surfactant mixtures under increasing surfactant concentrations within the dilute regime.
Immunotherapy with histamine dihydrochloride for the prevention of relapse in acute myeloid leukemia (2010)

Most patients with acute myeloid leukemia (AML) achieve complete remission (CR) after induction chemotherapy. Despite ensuing courses of consolidation chemotherapy, a large fraction of patients will experience relapses with poor prospects of long-term survival. Histamine dihydrochloride (HDC) in combination with the T-cell-derived cytokine IL-2 was recently approved within the EU as a remission maintenance immunotherapy in AML. HDC reduces myeloid cell-derived suppression of anti-leukemic lymphocytes, and aims to unravel a therapeutic benefit of IL-2 in AML by improving natural killer and T-cell activation. A randomized Phase III trial with 320 AML patients in CR demonstrated a significant reduction of relapse risk after immunotherapy with HDC plus low-dose IL-2 in the post-consolidation phase. HDC is the first approved therapeutic to target the state of immunosuppression in AML; further development in this area may comprise supplementary or alternative counter-suppressive agents with the aim to improve the efficacy of cancer immunotherapy.
Gastric emptying and fluid availability after ingestion of glucose and soy protein hydrolysate solutions in man (2003)

The double sampling gastric aspiration method was used to measure the effect of energy content on the rate of gastric emptying of glucose and soy protein hydrolysate solutions. The net rate of absorption of water from these solutions was assessed using deuterium oxide as a tracer for water. Six healthy male subjects were each studied on four separate occasions using a test drink volume of 600 ml. The half emptying times (t 1/2, median (range)) of the iso-energetic soy protein hydrolysate (6P, 60 g l(-1), 36 (14-39) min) and glucose (7G, 70 g l(-1), 25 (19-29) min) solutions were similar. These two solutions (6P, 7G) delivered energy to the small intestine at similar rates, and resulted in similar rates of accumulation of the deuterium tracer in the circulation. The dilute glucose solution (LG, 23 g l(-1)) was emptied faster (t 1/2 13 (11-19) min) and resulted in a faster rate of tracer accumulation in the circulation than any of the other solutions, including the iso-osmotic soy protein solution (LG 311 +/- 5 mosmol kg(-1), 6P 321 +/- 24 mosmol kg(-1)). The concentrated soy protein hydrolysate solution (12P, 120 g l(-1)) emptied more slowly (t 1/2 80 (44-120) min) than the more dilute solutions. The rate of energy delivery to the small intestine from 12P was similar to that from 6P for the first 50 min after ingestion, and similar to that from 7G at all sample points. These results indicate that the iso-energetic solutions of glucose and soy protein hydrolysate used in this study are emptied from the stomach at similar rates and result in similar rates of fluid availability after ingestion.
Transmission Line Modeling and Asymptotic Formulas for Periodic Leaky-Wave Antennas Scanning Through Broadside (2011)

It is shown, using three specific examples-a series fed patch (SFP) array, a phase reversal (PR) array and a composite right/left-handed (CRLH) antenna-that one-dimensional periodic leaky-wave antennas scanning through broadside build a class of leaky-wave antennas sharing qualitatively similar and quantitatively distinct dispersion and radiation characteristics. Based on an equivalent transmission line (TL) model using linearized series and shunt immittances to approximate the periodic (Bloch) antenna structure, asymptotic TL formulas for the characteristic propagation constant, impedance, energy, power and quality factor are derived for two fundamentally different near- and off-broadside radiation regimes. Based on these formulas, it is established that the total powers in the series and shunt elements are always equal at broadside, which constitutes one of the central results of this contribution. This equal power splitting implies a severe degradation of broadside radiation when only one of the two elements series or shunt efficiently contributes to radiation and the other is mainly dissipative. A condition for optimum broadside radiation is subsequently established and shown to be identical to the Heaviside condition for distortionless propagation in TL theory. Closed-form expressions are derived for the constitutive (LCRG) parameters of the TL model for the specific SFP, PR and CRLH antenna circuit models, and quantitative information on the validity range of the TL model is subsequently provided. Finally, full-wave simulation and measurement LCRG parameter extraction methods are proposed and validated.
High receptor binding affinity of lipoproteins in atypical dysbetalipoproteinemia (type III hyperlipoproteinemia). (1989)

Familial dysbetalipoproteinemia (or type III hyperlipoproteinemia) is characterized by the presence of abnormal, cholesteryl ester-rich beta-very low density lipoproteins (beta-VLDL) in the plasma. Subjects with typical dysbetalipoproteinemia are homozygous for an amino acid substitution in apolipoprotein (apo-) E at residue 158 and have defective apo-E-mediated binding of both pre-beta-VLDL and beta-VLDL to apo-B,E(LDL) (or LDL) receptors (1988. Chappell, D.A., J. Clin. Invest. 82:628-639). To understand the effect of substitutions in apo-E at sites other than residue 158, nine dysbetalipoproteinemic (dys-beta) subjects who were either homozygous or heterozygous for substitutions in apo-E at atypical sites were studied. These substitutions occurred at residue 142 (n = 6), 145 (n = 2), or 146 (n = 1) and are known to cause less defective binding than does the 158 substitution. The chemical composition and electrophoretic mobility of pre-beta-VLDL and beta-VLDL from atypical and typical dys-beta subjects were indistinguishable. However, lipoproteins from atypical and typical dys-beta subjects differed in their affinity for the apo-B,E(LDL) receptor on cultured human fibroblasts. The pre-beta-VLDL and beta-VLDL from atypical dys-beta subjects had 640- or 17-fold higher affinity, respectively, than did corresponding lipoproteins from typical dys-beta subjects. The higher binding affinity of lipoproteins from atypical dys-beta subjects was associated with a higher ratio of apo-E to total apo-C. Since higher binding affinity should cause more rapid receptor-mediated clearance of beta-VLDL in atypical than in typical dys-beta subjects in vivo, the mechanism of beta-VLDL accumulation may differ in these two groups.