gebhart/patrepeval huggingface dataset:
A New Mechanism for Trusted Code Remote Execution (2007)

Current authentication model in collaboration computing use entity's identity to establish trust relationship, this kind of security mechanism is at great risk. The identity authentication only can guarantee that the interactive entity's identities are real, but know nothing about the entities' security status and behaviors. Therefore it also needs to carry on the authentication to the entity's platform status, simultaneously needs to introduce a dynamic method which can carry on the authentication to the entity's behavior. This paper integratestrusted code remote execution the identity authentication, platform authentication and behavior authentication based on trusted computing technology, remote attestation and trusted behavior, proposes a new mechanism for trusted code remote execution. This mechanism can solve the problem of codes executing remotely effectively.
Physiology and Pharmacology of Striatal Neurons (2009)

The basal ganglia occupy the core of the forebrain and consist of evolutionarily conserved motor nuclei that form recurrent circuits critical for motivation and motor planning. The striatum is the main input nucleus of the basal ganglia and a key neural substrate for procedural learning and memory. The vast majority of striatal neurons are spiny GABAergic projection neurons, which exhibit slow but temporally precise spiking in vivo. Contributing to this precision are several different types of interneurons that constitute only a small fraction of total neuron number but play a critical role in regulating striatal output. This review examines the cellular physiology and modulation of striatal neurons that give rise to their unique properties and function.
Low Temperature Plasma‐Based Sterilization: Overview and State‐of‐the‐Art (2005)

Abstract Summary: Low temperature, high pressure, non‐equilibrium plasmas are now routinely used in several material processing applications, and in some cases are competing with low pressure plasmas in areas where these have historically been dominant. Etching and deposition are examples of such applications. Amongst the novel applications of non‐equilibrium plasmas, biomedical applications such as electrosurgery, surface modification of biocompatible materials, and the sterilization of heat‐sensitive medical tools are particularly interesting. In this paper, first a brief overview of recent research on reduced‐pressure plasma‐based sterilization/decontamination methods is given. Then a detailed review and discussion on the effects of atmospheric pressure non‐equilibrium plasmas on the cells of bacteria is presented. This includes the evaluation of the inactivation kinetics and the roles of the various plasma agents in the inactivation process. Measurements of the plasma temperature, the UV emission, and concentrations of various reactive species for the case of air plasma are presented. Plasma sub‐lethal effects are also briefly discussed, and the prospects of the use of “cold” plasmas in the biomedical field are outlined. magnified image
Der durch Salze der Platinmetalle katalysierte Austausch von Vinyl‐ und anderen ungesättigten Gruppen zwischen Estern und Carbonsäuren (1969)

Abstract Salze von Platinmetallen katalysieren den Austausch von Vinyl‐ Propenyl‐ und Isopropenyl‐sowie Allylgruppen zwischen Estern und Carbonsäuren. Durch massenspektrometrische Untersuchungen an 18 O‐markierten Verbindungen wird die Übertragung der Alkenylgruppe bewiesen, wie dies auch bei der quecksilbersalz‐katalysierten Reaktion der Fall ist. Der Nachweis der Konfigurationsumkehr bei der Umsetzung von cis ‐ oder trans ‐n‐Propenylacetat mit Natriumpropionat läßt auf einen stereospezifischen Reaktionsverlauf mit reversibler Bildung einer Acyloxymetallierungs‐Zwischenstufe schließen. Es wird angenommen, daß die cis‐trans ‐Isomerisierung von Alkenylestern nach demselben Mechanismus, nämlich als Umalkenylierung auf den gleichen Carboxylatrest, verläuft.
Ordered Structures in Polycarbonate Studied by Infrared and Raman Spectroscopy, Wide-Angle X-ray Scattering, and Differential Scanning Calorimetry (1998)

Ordered structures in samples of Bisphenol A polycarbonate (BPAPC) prepared by varying thermal and solvent conditions were investigated by infrared and Raman spectroscopy, wide-angle X-ray scattering (WAXS), and differential scanning calorimetry (DSC). Based on the spectroscopic analysis and ab initio quantum mechanical calculations of diphenyl carbonate as a model compound, an assignment of the bands conformationally sensitive to the trans−trans and cis−trans structures is proposed. Temperature dependences of the vibrational spectra of BPAPC show that cis−trans structure is the energetically preferred conformation in the amorphous state and in solution and its population can be increased with decreasing temperature in amorphous BPAPC even below the glass transition temperature. Differences in the degrees of ordering in semicrystalline BPAPC assessed from the vibrational spectra, WAXS, and DSC indicate partial order in the interfacial region between the crystalline and amorphous phases. In some solvents (toluene, benzene), aggregation of BPAPC occurs, leading to the ordered structure analogous to crystalline BPAPC. The order is preserved in semicrystalline BPAPC obtained by the room-temperature evaporation of the solvent.
Differential Histopathology and Chemokine Gene Expression in Lung Tissues following Respiratory Syncytial Virus (RSV) Challenge of Formalin-Inactivated RSV- or BBG2Na-Immunized Mice (2001)

A BALB/c mouse model of enhanced pulmonary pathology following vaccination with formalin-inactivated alum-adsorbed respiratory syncytial virus (FI-RSV) and live RSV challenge was used to determine the type and kinetics of histopathologic lesions induced and chemokine gene expression profiles in lung tissues. These data were compared and contrasted with data generated following primary and/or secondary RSV infection or RSV challenge following vaccination with a promising subunit vaccine, BBG2Na. Severe peribronchiolitis and perivascularitis coupled with alveolitis and interstitial inflammation were the hallmarks of lesions in the lungs of FI-RSV-primed mice, with peak histopathology evident on days 5 and 9. In contrast, primary RSV infection resulted in no discernible lesions, while challenge of RSV-primed mice resulted in rare but mild peribronchiolitis and perivascularitis, with no evidence of alveolitis or interstitial inflammation. Importantly, mice vaccinated with a broad dose range (20 to 0.02 microg) of a clinical formulation of BBG2Na in aluminium phosphate demonstrated histopathology similar to that observed in secondary RSV infection. At the molecular level, FI-RSV priming was characterized by a rapid and strong up-regulation of eotaxin and monocyte chemotactic protein 3 (MCP-3) relative gene expression (potent lymphocyte and eosinophil chemoattractants) that was sustained through late time points, early but intermittent up-regulation of GRO/melanoma growth stimulatory activity gene and inducible protein 10 gene expression, while macrophage inflammatory protein 2 (MIP-2) and especially MCP-1 were up-regulated only at late time points. By comparison, primary RSV infection or BBG2Na priming resulted in considerably lower eotaxin and MCP-3 gene expression increases postchallenge, while expression of lymphocyte or monocyte chemoattractant chemokine genes (MIP-1beta, MCP-1, and MIP-2) were of higher magnitude and kinetics at early, but not late, time points. Our combined histopathologic and chemokine gene expression data provide a basis for differentiating between aberrant FI-RSV-induced immune responses and normal responses associated with RSV infection in the mouse model. Consequently, our data suggest that BBG2Na may constitute a safe RSV subunit vaccine for use in seronegative infants.
A multistatic radar approach to soil moisture and vegetation monitoring at L band (2015)

This paper aims at identifying suitable geometrical configurations of a passive satellite radar flying in convoy with an active spaceborne SAR. The work has been performed in the frame of the SAOCOM-CS scientific investigations. It is a small satellite that ESA is conceiving to fly in convoy with the Argentinian SAOCOM 1B to acquire bistatic radar data at L-band. The applications foreseen in the paper are the retrieval of soil moisture and crop biomass. It is shown by a model based investigation that retrieval performances can be improved by combining monostatic and bistatic measurements in geometric configurations requiring very high along track and across track baselines.
A development of the motile sperm sorting microfluidic devices (2007)

The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file.
Pharmacokinetics of olanzapine long-acting injection (2014)

Olanzapine long-acting injection (OLAI) is a sustained-release depot antipsychotic for the treatment of schizophrenia in adults. Our objective was to explain the pharmacokinetics of OLAI to provide clinical insight. Simulation models and data from clinical trials are presented. Olanzapine concentrations were observed immediately upon injection. Half-life was ∼30 days, controlled by the slow rate of intramuscular absorption rather than the 30-h elimination rate-based half-life of oral olanzapine. As each injection builds on the drug still being released from previous injections, concentrations increase gradually until a steady state is reached after ∼3 months. Concentrations were similar to oral olanzapine and proportional to the dose; the average steady-state concentrations (10th-90th percentile) for the 150, 210, and 300 mg/2-week doses were 16-32, 15-55, and 20-67 ng/ml, respectively, and those for the 300 and 405 mg/4-week doses were 19-48 and 19-62 ng/ml, respectively. Peak concentrations most often occurred at 2-4 days after injection. Peak-to-trough fluctuation was greater for the 4-week dosing interval than the 2-week one, with no apparent clinical ramifications for these differences. Trough concentrations were above the lower end of the therapeutic range, even at the first injection. Long-term use up to 6 years indicated no additional accumulation. The impact of smoking and sex was similar, but less pronounced than for oral olanzapine.
The treatment of painful osseous metastases with phosphorus-32-labeled phosphates. (1993)

32P orthophosphate administered in a wide range of activity reduces or relieves the pain from osteoblastic metastases in approximately 80% of patients treated. The efficacy of this agent is equal to that of newer agents and of wide field radiotherapy, as documented in a literature review of 28 series reporting the use of 32P orthophosphate over a 50-year period. There is no dose-response relationship between the activity of 32P given and the percentage of patients experiencing pain reduction who received that activity. Only one death has been attributed to this radiopharmaceutical.
Numerical modelling of mechanisms involved in latchup triggering by a laser beam (1996)

The use of a laser beam is a well-known technique to trigger latchup parasitic structures in ICs. Numerical analyses of this phenomenon are brought into play to study its sensitivity when a continuous wave laser as well as pulsed lasers are used. The impact location is also studied to demonstrate that different mechanisms are involved in the triggering phase of latchup. The structure is more sensitive to blue light when it is directed over the well-substrate junction, while it is more sensitive to infrared light elsewhere. When using a CW laser, curves giving the power supply current versus the photo-induced current provide direct information on the parameters of the parasitic structure.
Sintering of Supported Metal Catalysts (2012)

The loss of active surface area produced by sintering is an important cause of catalyst deactivation during industrial operation and this is very important in the case of noble metal catalysts. Textural or structural promoters, which modify either the support or the metallic phase to stabilize the metallic particles, are commonly employed in the development of industrial catalysts.
Antibiotics and Pustulocystic Acne (1961)

The management of acne is one of the most difficult problems with which the dermatologist is faced. The use of antibiotics 1-10 has in recent years lent itself to the advancement of our ability to cope with this annoying disease. It may well be time for us to reevaluate our use of the so-called usual adjuvants to see if they are as of as much value as we have previously thought them to be. To my knowledge the only other double-blind study done on the problem of antibiotics and acne was a shortterm report 10 in which a chemotherapeutic agent was used with proved success. The following is a double-blind study of multiple antibiotics used over a long term with much local therapy omitted and some local therapy accentuated. Much has been written about the etiology of acne. No attempt will be made to review it here. An excellent review
The Malmö International Brother Study (MIBS): further support for genetic predisposition to inhibitor development (2001)

The issue of factors predisposing for inhibitor development in haemophilia patients is still largely unresolved. In an attempt to address this problem, we initiated a registry in 1996 of siblings with haemophilia and with or without a history of inhibitors. Four hundred and sixty families have accrued, of whom 388 suffer from haemophilia A and 72 haemophilia B. Twenty-five of the brother pairs are twins. The inhibitor incidence in all families with severe haemophilia A was 31.7%. The corresponding figure in the caucasian patients was 27.4%, whereas a higher incidence of inhibitors was reported in the black subjects (55.6%). Twins were reported in six of the 100 inhibitor families, for whom monozygocity was confirmed in three cases. In 32 families (32%), at least two brothers had a history of inhibitors. In 22 (69%) of these families, the inhibitor was also of the same type, i.e. either high- or low-responding. The overall concordance within the severe haemophilia A families was found to be 78.3% (195/249) compared to an expected figure of 68.0% and 58.0% using an inhibitor incidence of 20 and 30%, respectively (P < 0.0001). The corresponding figure for the twins was 88.2% (15/17). Moreover, the risk for inhibitor development in families with a previous inhibitor history was found to be 48% (95% confidence interval [CI] 35-62%), whereas the risk in families with no previous known inhibitor was only 15% (95% CI 11-21%) corresponding to a relative risk of 3.2 (95% CI 2.1-4.9). Immune-tolerance induction was reported in 24 families, of whom 13 siblings were successfully treated. Our data clearly support the concept that a genetic predisposition for inhibitor development exists. However, the markers of this predisposition remain to be elucidated and we believe that the MIBS registry will be useful for this purpose.
The role of subcutaneous tissue stiffness on microneedle performance in a representative in vitro model of skin (2016)

There has been growing interest in the mechanical behaviour of skin due to the rapid development of microneedle devices for drug delivery applications into skin. However, most in vitro experimentation studies that are used to evaluate microneedle performance do not consider the biomechanical properties of skin or that of the subcutaneous layers. In this study, a representative experimental model of skin was developed which was comprised of subcutaneous and muscle mimics. Neonatal porcine skin from the abdominal and back regions was used, with gelatine gels of differing water content (67, 80, 88 and 96%) to represent the subcutaneous tissue, and a type of ballistic gelatine, Perma-Gel®, as a muscle mimic. Dynamic nanoindentation was used to characterize the mechanical properties of each of these layers. A custom-developed impact test rig was used to apply dense polymethylmethacrylate (PMMA) microneedles to the skin models in a controlled and repeatable way with quantification of the insertion force and velocity. Image analysis methods were used to measure penetration depth and area of the breach caused by microneedle penetration following staining and optical imaging. The nanoindentation tests demonstrated that the tissue mimics matched expected values for subcutaneous and muscle tissue, and that the compliance of the subcutaneous mimics increased linearly with water content. The abdominal skin was thinner and less stiff as compared to back skin. The maximum force decreased with gel water content in the abdominal skin but not in the back skin. Overall, larger and deeper perforations were found in the skin models with increasing water content. These data demonstrate the importance of subcutaneous tissue on microneedle performance and the need for representative skin models in microneedle technology development.
Domain wall motion induced by strong microwave fields (1974)

A new high power effect in ferrites, the motion of domain walls induced by microwave pulses is described. In high power phase shifters using ferrite toroids this effect can change the remanent magnetization and hence change the insertion phase of the device. A theoretical explanation of these effects is obtained by considering a partially magnetized ferrite material having uniaxial anisotropy and exposed to an rf magnetic field perpendicular to the anisotropy axis. Experiments at 3 GHz on a twin-slab (i.e., toroid) phase shifter at peak power levels up to 300 kW are in good agreement with the theoretical expectations. It is shown that a circularly polarized rf magnetic field of strength h <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">o</inf> exerts substantially the same pressure on domain walls as a dc magnetic field applied along the domain axis and having the strength <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">H_{z} = \gammah\min{o}\max{2}\omega</tex> w, where γ is the gyromagnetic ratio and ω the angular frequency. The rf generated pressure tends to shrink those domains in which the imposed sense of circular polarization coincides with the sense of the natural spin precession.
Intelligent network feature transaction interface (1988)

The feature transaction interface and associated software structures required to support an intelligent network are addressed. A layer service logic execution environment is used to describe the operation of the feature transaction interface for provisioning intelligent network services. Included in the discussion are: the need for service creation; unbundled service logic for functional flexibility; remote operation using the SS7 network; and reduced service-provisioning intervals. Service examples using the feature transaction interface are given.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Synthesis of 3,4,5-Trisubstituted-1,2,4-triazoles (2010)

International audience
Microelectromechanical flexure PZT actuated optical scanner: static and resonance behavior (2005)

An optical, mirror system has been built using MEMS techniques while employing lead zirconate titanate (PZT) thin films as strong piezoelectric material. The system consists of two parallel silicon cantilever beams, on which the PZT was deposited, which were arranged to project inward from a common frame. The beams were laterally offset over a distance appropriate to fit a mirror between them. One end of each beam is fixed to the frame, while the other end is attached to a sideways projected bar, directed to the other beam. To each sideways bar a connector, parallel to the original beam, pointing toward the frame, was attached. Between both connectors a mirror was attached. The application of voltage across the electrodes on top and below the PZT causes the beams to bend as a monomorph, and the mirror between the beams to rotate around an axis through its center. A variety of thicknesses have been chosen to fabricate these devices. The mirror angle at a given voltage is inversely proportional to the square of the beam thickness, while the bandwidth is proportional to the thickness. Beams with thickness of 5 µm were used to achieve optical angles in static mode of up to 40° using voltages up to 13 V. In that case a bandwidth of around 700 Hz was observed. In resonance optical angles of 10° with a driving voltage as low as 100 mV were achieved. For devices with 30 µm thick beams, optical angles of up to 30° were observed in resonance at 17.4 kHz at driving voltages of around 6 V. Due to the proprietary design a figure of merit which may be defined as a product of the resonance frequency and optical angle, is much higher than one of the other PZT scanners.
The effectiveness of a sulfluramid concentrate mixed with canned sardine cat-food for control of wasps (1996)

A bait freshly-prepared by mixing a sulfluramid concentrate with canned sardine cat-food was compared with previously-frozen Finitron Wasp Bait for efficacy against wasps. The effectiveness of the two baits was determined by counting wasps collecting bait and wasps leaving or entering nests within 150 m of bait stations before and after poisonbaiting. Both baits reduced wasp numbers in nests by >85% within 3 weeks. Wasp numbers in nests were reduced more rapidly and to a lower level by the bait made from the sulfluramid concentrate than by Finitron Wasp Bait. No decision about the commercial availability of the sulfluramid concentrate has yet been made.
Effects of Wafer Cleaning and Annealing on Glass/Silicon Wafer Direct Bonding (2004)

We studied cleaning and annealing effects in glass/Si direct bonding using 4 inch Pyrex glass and silicon wafers. SPM cleaning (sulfuric-peroxide mixture, H2SO4:H2O2=4:1,120°C), RCA cleaning (NH4OH:H2O2:H2O=1:1:5,80°C), and combinations of these two methods were examined to investigate the wafer cleaning effect. When wafers were cleaned by RCA after SPM cleaning, maximal bonding quality at room temperature was gained. Surface roughness, as measured by AFM (atomic force microscope), was found to correspond with bonding quality at room temperature. Bonding strength increased as the annealing temperatures increased to 400°C, but debonding occurred at 450°C. The difference in thermal expansion coefficients of the glass and the Si wafer used led to this debonding. When wafers bonded at room temperature were annealed at 300 or 400°C, the bonding strength increased for 28 hours, and then it decreased with further annealing. The decrease in bonding strength caused by further annealing was due to sodium ion drift through the glass/Si interface.