gebhart/patrepeval huggingface dataset:
The Oil and Protein in Nuts of Macadamia tetraphylla L. Johnson, Macadamia integrifolia Maiden and Betche, and Their F1 Hybrid1 (1973)

Abstract Oil, corresponding in amount to 6-14% of the original nut weight, was extracted from intact macadamia kernels by immersing them in petroleum ether for 48 hours at room temperature. Drying the extracted nuts in a vented oven at 55°C for 24 hours removed the odor and taste of the solvent and their flavor seemed to equal or excel that of nonextracted nuts. Oil thus recovered and marketed could provide additional revenue to the macadamia industry. Nuts of M. tetraphylla and of M. integrifolia were equal in oil content (74.9%) with an iodine value of 71.8 and 75.4, respectively. Macadamia oil had outstanding stability. The 8 major fatty acids in the oil and their mean percentages in the 2 species and their F 1 and F 2 hybrids were: myristic (0.60), palmitic (8.7), palmitoleic (22.1), stearic (3.6), oleic (59.1), linoleic (1.8), arachidic (2.2), and eicosenoic (1.5). The mean protein content in the lipid free meal of the parental and F 1 populations was 36.5%. Arginine, aspartic acid, glutamic acid, and leucine made up about 52% of total amino acids recovered in each of the 2 species and the F 1 generation.
Copper Complexes of Chiral Tetradentate Binaphthyl Schiff-Base Ligands: Syntheses, X-ray Crystal Structures and Activity in Catalytic Asymmetric Cyclopropanation of Alkenes (2002)

A number of new chiral monomeric binaphthyl Schiff-base ligands H2L [where H2L = 2,2′-bis(3-R1-5-R2-2-hydroxybenzylideneamino)-1,1′-binaphthyl] and a series of chiral copper(II) complexes [CuL] were prepared in good or nearly quantitative yields. Some of the free ligands and the [CuL] complexes were structurally characterized by X-ray crystallography. Almost all the [CuL] complexes were found to be active catalysts for the asymmetric cyclopropanation of alkenes with ethyl or tert-butyl diazoacetate. Enantioselectivities of up to 77% ee were observed. (© Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002)
H<sub>2</sub>O<sub>2</sub> Sensor Based on the Room-Temperature Phosphorescence of Nano TiO<sub>2</sub>/SiO<sub>2</sub> Composite (2007)

A TiO2/SiO2 composite prepared by the sol-gel route can produce highly emissive broadband room-temperature phosphorescence at an excitation wavelength of 403 nm. The white phosphorescence of TiO2/SiO2 could be quenched by H2O2. The phosphorescence quenching effect demonstrated excellent sensitivity and high selectivity to H2O2. Furthermore, the phosphorescence of TiO2/SiO2 can be recovered when it is dipped in a hydroxylamine hydrochloride solution. Therefore, the TiO2/SiO2 was used to develop a reproducible phosphorescence sensor for H2O2. It has been successfully applied to the determination of H2O2 in the enzymatic catalytic reaction and real samples.
Design, Synthesis, and Biological Evaluation of Novel Selenium (Se-NSAID) Molecules as Anticancer Agents (2016)

The synthesis and anticancer evaluation of novel selenium-nonsteroidal anti-inflammatory drug (Se-NSAID) hybrid molecules are reported. The Se-aspirin analogue 8 was identified as the most effective agent in reducing the viability of different cancer cell lines, particularly colorectal cancer (CRC) cells, was more selective toward cancer cells than normal cells, and was >10 times more potent than 5-FU, the current therapy for CRC. Compound 8 inhibits CRC growth via the inhibition of the cell cycle in G1 and G2/M phases and reduces the cell cycle markers like cyclin E1 and B1 in a dose dependent manner; the inhibition of the cell cycle may be dependent on the ability of 8 to induce p21 expression. Furthermore, 8 induces apoptosis by activating caspase 3/7 and PARP cleavage, and its longer exposure causes increase in intracellular ROS levels in CRC cells. Taken together, 8 has the potential to be developed further as a chemotherapeutic agent for CRC.
An exposed approach to reliable multicast in heterogeneous logistical networks (2003)

An exposed approach in computer service architecture is one that offers client software a primitive service whose semantics are closely based on the underlying physical infrastructure. The exposed approach relies on the client to build higher-level services, with more abstract semantics, out of such primitive tools using sophisticated compilation or run-time algorithms. Current approaches to reliable multicast focus on encapsulated algorithms for efficient retransmission of datagrams to sets of receivers that require them. These approaches include augmenting the primary multicast data channel with direct TCP connections or with secondary multicast channels for retransmissions, and on the possibility of retransmissions originating from nodes in the middle of the network. In this paper we offer an exposed approach to multicast that uses an underlying Logistical Networking infrastructure that makes possible the implementation of any of the current retransmission algorithms, as well as new strategies yet to be devised.
Summary Based Static Analysis for Practical Search for Defects in C Programs and Libraries (2014)

This paper considers an algorithm for scalable automatic static analysis to detect defects in programs written in C. We propose a criterion for emitting warnings based on reach ability of function statements. Main advantages of the proposed approach are scalability, high true positive rate and ability to perform library analysis.
Synthesis of <i>N</i>-Unsubstituted Di- and Triaza Crown Ethers (1983)

Abstract Facile syntheses of di- and triaza crown ethers by in tramolecular cyclization of oligoethylene glycols containing two or three imino groups or by their intermolecular cyclization with oligoethylene glycol bis(p-toluenesulfonate)s are described.
Total Synthesis of (±)-Epoxysorbicillinol (2001)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTTotal Synthesis of (±)-EpoxysorbicillinolJohn L. Wood, Brian D. Thompson, Naeem Yusuff, Derek A. Pflum, and Mike S. P. MatthäusView Author Information Sterling Chemistry Laboratory, Department of Chemistry Yale University, New Haven, Connecticut 06520-8107 Cite this: J. Am. Chem. Soc. 2001, 123, 9, 2097–2098Publication Date (Web):February 10, 2001Publication History Received16 November 2000Published online10 February 2001Published inissue 1 March 2001https://pubs.acs.org/doi/10.1021/ja0057979https://doi.org/10.1021/ja0057979rapid-communicationACS PublicationsCopyright © 2001 American Chemical SocietyRequest reuse permissionsArticle Views3043Altmetric-Citations56LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (4)»Supporting Information Supporting Information SUBJECTS:Alcohols,Cyclization,Ketones,Organic compounds,Organic reactions Get e-Alerts
Hyaluronic Acid Facilitates the Recovery of Hematopoiesis following 5‐Fluorouracil Administration (2004)

The fate of hematopoietic stem cells (HSCs) is determined by microenvironmental niches, but the molecular structure of these local networks is not yet completely characterized. Our recent observation that glycosaminoglycan hyaluronic acid (HA), a major component of the bone marrow extracellular matrix, is required for in vitro hematopoiesis led us to suggest a role for HA in structuring the hematopoietic niche. Accordingly, HA deprivation induced by various treatments might lead to an imbalance of normal HSC homeostasis. Since 5-fluorouracil (5-FU) administration sharply decreases the amount of cell surface-associated HA in bone marrow, we examined whether the administration of exogenous HA enhances suppressed hematopoiesis in 5-FU-treated mice. HA administered to mice following 5-FU infusion facilitated the recovery of leukocytes and thrombocytes in the peripheral blood. Intravenously infused HA was found in the bone marrow, where it bound endothelial cells and resident macrophages and increased expression of the hematopoiesis-supportive cytokines interleukin-1 and interleukin-6. In agreement with these observations, enhanced hematopoietic activity was detected in the bone marrow, as measured by elevated counts of long-term culture-initiating cells (LTC-ICs), committed progenitors, and the total number of mature bone marrow cells. Overall, our results suggest that HA is required for regulation of the hematopoiesis-supportive function of bone marrow accessory cells and, therefore, participates in hematopoietic niche assembly.
Clinical and biologic relevance of immunologic marker studies in childhood acute lymphoblastic leukemia (1993)

Immunologic marker studies of the lymphoid leukemias have greatly improved the precision of diagnosis of these disorders by providing specific information regarding the lineage and stage of maturation of the malignant cells. Such studies have also enhanced our understanding of normal lymphocyte development, permitting reproducible identification of lymphoid cells in discrete developmental stages. By elucidating the functions of lymphoid cell differentiation antigens, it has been possible to gain insight into the signal transduction mechanisms by which these cells interact among themselves and with other cell types. Similar studies have shown that ALL is an immunophenotypically heterogeneous disease with clinically important subtypes representing clonal expansions of lymphoblasts at different stages of maturation. Furthermore, successful correlation of immunophenotype with certain karyotypic and molecular abnormalities, which appear to underlie most or all leukemias, were made possible by the inclusion of immunologic marker assessment. Interestingly, many of these phenotype-related abnormalities have involved either the Ig or TCR genes, thus providing additional clues to the mechanisms of leukemogenesis. Knowledge of the immunologic features of leukemic cells has been essential for the generation of phenotype-specific response data in the context of modern therapy for ALL. With wider use of intensive treatment, the traditional prognostic distinctions among immunophenotypes have begun to disappear; however, certain classes of agents have more favorable toxicity/efficacy ratios against some immunophenotypes than others, justifying continued efforts to target therapy by immunologic species of ALL. Antibody-toxin conjugates, or immunotoxins, have induced complete responses in preliminary trials and may prove clinically useful, perhaps in combination with chemotherapy, if their toxic side effects can be controlled. Finally, immunologic markers may serve as sensitive targets for the detection of minimal residual disease; the clinical usefulness of this approach will depend on prospective comparisons with molecular methods.
The Federal Registration Process and Requirements for the United States (2003)

The US Environmental Protection Agency (EPA) regulates pesticides under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Federal Food, Drug, and Cosmetic Act (FFDCA). Under FIFRA, the EPA is authorized to regulate pesticides to ensure that their use does not cause unreasonable adverse effects to humans and the environment. Under FFDCA, EPA has the responsibility to establish tolerances for pesticide residues on food crops. A tolerance is the maximum allowable residue of a pesticide on food. Such regulatory oversight is designed to minimize risks while allowing the public to benefit from pesticide use. Prior to lawful use in commerce, a pesticide must be registered by the EPA, unless specifically exempted by regulation. Registrants of pesticides are responsible for submitting specific data to the agency to support the conclusion that the pesticide will not significantly increase the risk of adverse effects to humans or to the environment. Once a pesticide is registered by the EPA, it may be sold and distributed in the United States and used as specified on the approved label.
Treating Primary Liver Cancer with Hepatic Arterial Infusion of Floxuridine and Dexamethasone: Does the Addition of Systemic Bevacizumab Improve Results (2011)

Adding Bev to HAI FUDR/Dex appeared to increase biliary toxicity without clear improvement in outcome (median PFS 8.45 vs. 7.3 months, and median survival 31.1 vs. 29.5 months, for HAI + Bev vs. HAI alone groups, respectively).
<title>Rigorous electromagnetic modeling of diffractive optical elements</title> (1991)

Diffractive optical elements are becoming a standard optical design element. However, their fundamental performance is most often modeled using scalar theories which leads to optimistic performance levels. In this paper, scalar approximations are compared to rigorous electromagnetic solutions for various diffractive optical elements.
Heat Transfer by Free Convection from Horizontal Cylinders in Diatomic Gases (1954)

The case of the horizontal cylinder is of particular importance in the study of heat transfer by free convection for the following reasons: In the first place, next to the rectangular plate it represents the simplest two-dimensional case; and second, a very wide range of measurements is possible, from the finest electrically heated glow lamp wires to pipes heated by liquids or gases flowing through them.
CD8 <sup>+</sup> CD11 <sup>+</sup> Suppressor Cells in HIV-Infected Asymptomatic Patients: Effect on HIV-Specific Cytotoxicity (1992)

CD3+CD8+CD11+ cells were present in the peripheral blood of patients infected with asymptomatic human immunodeficiency virus (HIV) in higher percentage (10-20%) than in normal individuals (3-5%) in this study. These cells, through the release of soluble factors, significantly suppressed the effector phase of anti-HIV cytotoxic activities, both human leukocyte antigen (HLA)-class I or class II restricted, and nonrestricted. The effectors were CD8+CD11-, CD4+ T cells, and CD16+ cells for HLA-class I, class II restricted, and nonrestricted cytotoxicities, respectively. The soluble factors also inhibited natural killer cell activity. Thus, this effect was neither HLA-restricted nor antigen-specific. These CD3+CD8+CD11+ cells may be an important immunopathogenic factor in HIV disease.
All-optical switching using the quantum Zeno effect and two-photon absorption (2009)

We have previously shown that the quantum Zeno effect can be used to implement quantum logic gates for quantum computing applications, where the Zeno effect was produced using a strong two-photon absorbing medium. Here we show that the Zeno effect can also be used to implement classical logic gates whose inputs and outputs are high-intensity fields (coherent states). The operation of the devices can be understood using a quasistatic analysis, and their switching times are calculated using a dynamic approach. The two-photon absorption coefficient of rubidium vapor is shown to allow operation of these devices at relatively low power levels.
<title>Wavelength compensation by time reverse ray tracing</title> (1995)

We specified 406 mm diameter off axis powered HOEs to operate at 1.06 microns and for trials at 670 nm, then looked for ways to construct them at 488 nm. We were able to write holographic surfaces directly in Zemax, then play back other wavelengths through them to display the aberrations that needed to be canceled. Zemax had easy entry and optimization routines that allowed us to do cut and try construction variations on screen rather than on the table. We designed construction set ups using only off the shelf lenses and mirrors and were able then to fabricate the HOEs with only small incremental improvements being made on the table. The computed spot sizes were less than .5 mm diameter and constructed holographic optics were on Bragg with outputs as small as .5 mm and high efficiencies.
Tissue Culture of Callus from Seedling and Adult Stages of Hedera helix (1970)

Callus from stem pieces of the juvenile (seedling) and adult stages of Hedera helix L. were grown for up to 17 passages on a medium containing mineral salts, vitamins, sucrose, and coconut water and for fewer passages on media which lacked coconut water. Seedling callus differed in its growth in culture from adult. It was less stable than the adult; i.e., it developed vigorous variants earlier and more freely than the adult callus. The tendency of seedling callus to adapt to unfavorable media was greater. On low salt media root formation by callus was infrequent. Adult calluses formed roots more freely on high salt media than seedling calluses did.
Synthesis and Modeling Studies with Monocyclic Analogues of Mycophenolic Acid (1996)

Two stepwise procedures, developed for the introduction of the (E)-4-methyl-4-hexenoic acid side chain of mycophenolic acid, were used in the synthesis of monocyclic mycophenolic acid analogues 2a-i. The derivatives with a methyl group or hydrogen at C-4 and lacking the lactone moiety were much less cytotoxic than mycophenolic acid. The monocyclic analogues with a C-4 chloro group did show some activity, albeit much less than mycophenolic acid. The observed differences in potency are rationalized by semiempirical calculations of intramolecular H-bonds.
Vehicle detection and tracking in video (2002)

We present a scheme for vehicle detection and tracking in video. The proposed method effectively combines statistical knowledge about the class of vehicles with motion information. The unknown distribution of the image patterns of vehicles is approximately modeled using higher-order statistical information derived from sample images. Statistical information about the background is learnt "on the fly". A motion detector identifies regions of activity. The classifier uses a higher-order statistical closeness measure to determine which of the objects actually correspond to moving vehicles. The tracking module uses position co-ordinates and difference measurement values for correspondence. Results on real video sequences are given.
Introduction to RCCL: A robot control &amp;C&amp; library (2005)

RCCL is a robot programming system that enables a user to specify robot manipulator tasks employing a set of primitive system calls similar in spirit to those of the UNIX input-output system. The goals addressed in the RCCL system are: manipulator task description; sensor integration; updatable world representation; flexibility; wide range of applications; medium level robot programming; off-line programming; efficiency; manipulator independence; portability; foreground-background programming; Cartesian path programming; arbitrary path specification; tracking; force control.
Sampled fiber Bragg grating for simultaneous refractive-index and temperature measurement (2001)

We present a novel scheme for simultaneous measurement of temperature and refractive index by use of a single sampled fiber Bragg grating (SFBG). The intrinsic nature of a SFBG that possesses both fiber Bragg grating and long-period grating spectral responses permits the temperature effect to the measured solely from the former, whereas the refractive-index information is extracted from the latter. Using such a dual-parameter sensor, we successfully demonstrated measurement of the dependence on temperature of the refractive index of an aqueous solution of sucrose.
The role of lavage in preventing hemodynamic and blood-gas changes during cemented arthroplasty. (1983)

During cemented arthroplasty, thorough lavage of a plugged medullary canal prior to insertion of the cement and prosthesis is a highly effective prophylactic measure in the elimination of gas-exchange and hemodynamic complications.
Applications of artificial intelligence for chemical inference. XVII. Approach to computer-assisted elucidation of molecular structure (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTApplications of artificial intelligence for chemical inference. XVII. Approach to computer-assisted elucidation of molecular structureRaymond E. Carhart, Dennis H. Smith, Harold Brown, and Carl DjerassiCite this: J. Am. Chem. Soc. 1975, 97, 20, 5755–5762Publication Date (Print):October 1, 1975Publication History Published online1 May 2002Published inissue 1 October 1975https://pubs.acs.org/doi/10.1021/ja00853a021https://doi.org/10.1021/ja00853a021research-articleACS PublicationsRequest reuse permissionsArticle Views157Altmetric-Citations88LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
From wheat straw to bioethanol: integrative analysis of a separate hydrolysis and co-fermentation process with implemented enzyme production (2015)

Y Ethanol-Process is a measure for the efficiency of the lignocellulose-to-bioethanol process. Based on mass balance analysis, the correlations between single process parameters and Y Ethanol-Process were elucidated. The optimized laboratory scale SHCF process showed efficiencies similar to pilot scale plants. The herein presented process analysis can serve as effective and simple tool to identify key process parameters, bottlenecks, and future optimization targets.