gebhart/patrepeval huggingface dataset:
Multimodal Event Detection in User Generated Videos (2011)

Nowadays most camera-enabled electronic devices contain various auxiliary sensors such as accelerometers, gyroscopes, compasses, GPS receivers, etc. These sensors are often used during the media acquisition to limit camera degradations such as shake and also to provide some basic tagging information such as the location used in geo-tagging. Surprisingly, exploiting the sensor-recordings modality for high-level event detection has been a subject of rather limited research, further constrained to highly specialized acquisition setups. In this work, we show how these sensor modalities, alone or in combination with content-based analysis, allow inferring information about the video content. In addition, we consider a multi-camera scenario, where multiple user generated recordings of a common scene (e.g., music concerts, public events) are available. In order to understand some higher-level semantics of the recorded media, we jointly analyze the individual video recordings and sensor measurements of the multiple users. The detected semantics include generic interesting events and some more specific events. The detection exploits correlations in the camera motion and in the audio content of multiple users. We show that the proposed multimodal analysis methods perform well on various recordings obtained in real live music performances.
Multicentre trials of praziquantel in human schistosomiasis: design and techniques. (1979)

This paper outlines the experimental design and techniques used in the initial multicentre clinical experiences with praziquantel in the treatment of human infections due to Schistosoma haematobium, S. mansoni, and S. japonicum. Trials were conducted in Brazil, Japan, the Philippines, and Zambia.Close professional cooperation between informed representatives of the manufacturers of the drug and WHO led to the use of a standard clinical trial design and agreed technical protocols, although parasitological methods of therapeutic assessment varied with the species of infecting parasite. Double-blind studies of tolerance were conducted at three different dose levels and subsequently, in Brazil and Zambia, single-blind trials of parasiticidal efficacy were carried out. The results of the various trials are reported separately.This type of close professional cooperation is a useful model for initial clinicopharmacological studies of parasiticidal drugs-an area beset with difficulties for both industry and international agencies.
Onboard pilot decision aid for high volume operations in self-controlled airspace (2005)

Distributed pilot decision-making plays a critical part in high volume operation in non-controlled/non-radar airports, a concept proposed by the NASA Small Aircraft Transportation System program. Realization of the concept relies on advanced cockpit systems that assist pilots in both information-processing and decision-making. In this paper, we presented the design of an onboard pilot decision aid system, called the Small Aircraft Pilot Assistant, which is dedicated to help pilots perform the high volume operation flight tasks. It increases the cockpit decision-making capacity and pilot situation awareness by automating part of the pilot decision-making process, especially in its early stages of information acquisition and analysis. The pilot tests of the system are conducted using a real-time, multi-aircraft, pilot-in-the-loop simulation system that is presently capable of middle-fidelity HVO simulation.
Metal-ferroelectric-metal capacitor based persistent memory for electronic product code class-1 generation-2 uhf passive radio-frequency identification tag (2009)

With the circuits using metal-ferroelectric-metal (MFM) capacitor, rf operational signal properties are almost the same or superior to those of polysilicon-insulator-polysilicon, metal-insulator-metal, and metal-oxide-semiconductor (MOS) capacitors. In electronic product code global class-1 generation-2 uhf radio-frequency identification (RFID) protocols, the MFM can play a crucial role in satisfying the specifications of the inventoried flag’s persistence times (Tpt) for each session (S0–S3, SL). In this paper, we propose and design a new MFM capacitor based memory scheme of which persistence time for S1 flag is measured at 2.2 s as well as indefinite for S2, S3, and SL flags during the period of power-on. A ferroelectric random access memory embedded RFID tag chip is fabricated with an industry-standard complementary MOS process. The chip size is around 500×500 μm2 and the measured power consumption is about 10 μW.
Solid state 13C NMR study of collagen molecular dynamics in hard and soft tissues. (1983)

The molecular dynamics of the collagen backbone in intact connective tissues has been elucidated using 13C line shape analysis. Since one-third of the amino acid residues in collagen are glycines, we have labeled: (a) reconstituted lathrytic (uncross-linked) chick calvaria collagen fibrils; (b) rat tail tendon (cross-linked); and (c) rat calvaria (cross-linked and mineralized) collagen with [1-13C]glycine. The proton-enhanced and normal 90 degrees - t proton-decoupled spectrum of each collagen sample shows an asymmetric chemical shift powder pattern for the glycine carbonyl carbon. The powder line width, delta, (delta = sigma zz - sigma xx) at 22 degrees C for the uncross-linked reconstituted collagen fibril is 108 ppm, whereas the maximum value of delta (140 ppm) is observed for the cross-linked and mineralized collagen fibrils in rat calvaria. The powder line widths for the cross-linked fibrils in tail tendons and demineralized calvaria are 124 and 120 ppm, respectively. However, since the same line shape and line width (145 ppm) are observed for all samples at -35 degrees C, the difference in delta values observed at room temperature is attributed to differences in molecular mobility of collagen in various samples. The line shapes are analyzed using a dynamic model in which azimuthal orientation of the collagen backbone is assumed to fluctuate as a consequence of reorientation about the helix axis. The observed line shapes are sensitive to motions having correlation times less than approximately 10(-4) s and the analysis provides the values of the root mean square fluctuation in azimuthal angle, gamma rms, due to such motions. It is found that gamma rms equals 41 degrees, 33 degrees, and 14 degrees for the uncross-linked, cross-linked, and mineralized collagens, respectively. These results provide the first information about the extent that cross-linking and mineralization restrict molecular motion in collagen.
Optimum design of minimum drag bodies in incompressible laminar flow using a control theory approach (1994)

The problem of modifying the shape of a two-dimensional body to reduce its drag while maintaining its section area (volume per unit span) constant is addressed. Two-dimensional, incompressible, laminar flow governed by the steady-state Navier-Stokes equations is assumed about the body. In this paper, a set of “adjoint” equations is obtained, the solution to which permits the calculation of the direction and relative magnitude of change in the body profile that leads to a lower viscous drag. The direct as well as the adjoint set of partial differential equations are obtained for Dirichlet-type far-field conditions. Repeatedly modifying the body shape with each solution to these two sets of equations with the above boundary conditions, would lead to a body with minimum drag, for a specified section area. For such a body it is shown that the product of shear and the “adjoint” shear is constant everywhere along the body. Even though the viscous terms are retained in the direct and the adjoint equations, in order to determine farfield boundary conditions, the characteristics of the adjoint set of equations are examined in the absence of the viscous terms. This is done in order to obtain computationally tractable boundary conditions at far-field instead of the Dirichlet type conditions required by analysis. Numerical solutions to the direct and the adjoint equations are obtained using these modified boundary conditions. Preliminary results obtained using an ellipse as the initial body shape demonstrate that the approach does provide meaningful shape modification information.
Aneurysms of the septum primum in adults. (1978)

Sixteen aneurysms of the septum primum were found at autopsy among 1,578 adults. Most occurred in individuals in their fifth or sixth decade. All aneurysms were asymptomatic and none were diagnosed before death. Fourteen bulged into the right ventricle. The aneurysm may develop in patients with a raised intra-atrial pressure but most seemed associated with normal intra-atrial pressures. A particular morphology of the fossa ovalis region may predispose the septum to aneurysm formation. Echocardiographic and angiographic features of the aneurysm need definition to distinguish them from those caused by other lesions.
A 288-kb fully parallel content addressable memory using a stacked-capacitor cell structure (1992)

A 288-kb (8 K words*36 b) fully parallel content addressable memory (CAM) LSI using a compact dynamic CAM cell with a stacked-capacitor structure and a novel hierarchical priority encoder is described. The stacked-capacitor structure results in a very compact dynamic CAM cell (66 mu m/sup 2/) which is operationally stable. The novel hierarchical priority encoder reduces the circuit area and power dissipation. In addition, a new priority decision circuit is introduced. The chip size is 10.3 mm*12.0 mm using a 0.8- mu m CMOS process technology. A typical search cycle time of 150 ns and a maximum power dissipation of 1.1 W have been obtained using circuit simulation. In fabricated CAM chips, the authors have verified the performance of a search operation at a 170-ns cycle and have achieved a typical read/write cycle time of 120 ns.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Lipid-AuNPs@PDA Nanohybrid for MRI/CT Imaging and Photothermal Therapy of Hepatocellular Carcinoma (2014)

Multifunctional theranostic nanoparticles represent an emerging agent with the potential to offer extremely sensitive diagnosis and targeted cancer therapy. Herein, we report the synthesis and characterization of a multifunctional theranostic agent (referred to as LA-LAPNHs) for targeted magnetic resonance imaging/computed X-ray tomography (MRI/CT) dual-mode imaging and photothermal therapy of hepatocellular carcinoma. The LA-LAPNHs were characterized as having a core-shell structure with the gold nanoparticles (AuNPs)@polydopamine (PDA) as the inner core, the indocyanine green (ICG), which is electrostatically absorbed onto the surface of PDA, as the photothermal therapeutic agent, and the lipids modified with gadolinium-1,4,7,10-tetraacetic acid and lactobionic acid (LA), which is self-assembled on the outer surface as the shell. The LA-LAPNHs could be selectively internalized into the hepatocellular cell line (HepG2 cells) but not into HeLa cells due to the specific recognition ability of LA to asialoglycoprotein receptor. Additionally, the dual-mode imaging ability of the LA-LAPNH aqueous solution was confirmed by enhanced MR and CT imaging showing a shorter T1 relaxation time and a higher Hounsfield unit value, respectively. In addition, the LA-LAPNHs showed significant photothermal cytotoxicity against liver cancer cells with near-infrared irradiation due to their strong absorbance in the region between 700 and 850 nm. In summary, this study demonstrates that LA-LAPNHs may be a promising candidate for targeted MR/CT dual-mode imaging and photothermal therapy of hepatocellular carcinoma.
COX‐2‐mediated Inflammation in Fat Is Crucial for Obesity‐linked Insulin Resistance and Fatty Liver (2009)

The aim was to examine the role of cyclooxygenase (COX)-2-mediated inflammation in the development of obese linked insulin resistance and fatty liver. The rats were fed separately regular diet (CONT), high-fat diet (HFD) ad libitum, or energy restrictedly for 12 weeks. Rats fed HFD ad libitum were further divided into three subgroups co-treated with vehicle (HFa), or a selective COX-2 inhibitor celecoxib (HFa-Cel) or mesulid (HFa-Mes). Euglycemic hyperinsulinemic clamp (EHC) experiment was performed at the end of study. Another set of rats with similar grouping was further divided into those with a 4, 8, or 12-week intervention period for hepatic sampling. Body weight was increased significantly and similarly in HFa, HFa-Cel, and HFa-Mes. Time-dependent increases in plasma insulin, glucose, 8-isoprostanes, leptin levels, homeostasis model assessment of insulin resistance (HOMA-IR) and hepatic triglyceride contents shown in HFa were significantly reversed in HFa-Cel and HFa-Mes. During EHC period, the reduction in stimulation of whole body glucose uptake, suppression of hepatic glucose production and metabolic clearance rate of insulin shown in HFa were significantly reversed in HFa-Cel and HFa-Mes. The enhanced COX-2 and tumor necrosis factor-alpha (TNF-alpha) but attenuated PPAR-gamma and C/EBP-alpha mRNA expressions in epididymal fat shown in HFa were significantly reversed in HFa-Cel and HFa-Mes. The increases in average cell size of adipocytes and CD68 positive cells shown in HFa were also significantly reversed in HFa-Cel and HFa-Mes. Our findings suggest that COX-2 activation in fat inflammation is important in the development of insulin resistance and fatty liver in high fat induced obese rats.
The Femtoprint Project (2012)

The Femtoprint project, a European project, aims at demonstrating the use of low-energy laser pulses (i.e. below the ablation threshold) to manufacture monolithically integrated devices including optofluidic, optomechanical and photonic devices. The longer-term objective is the implementation of a versatile table-top machining center. This paper summarizes the project progress to date and demonstrates the potential of this approach through various illustrative examples.
Design, Implementation and Performance Analysis of Concurrency Control Algorithm with Architecture for Temporal Database (2016)

Concurrency control mechanism is one of the critical factors which affect the overall performance of database system. The conflicting situations are normal phenomena in multiuser distributed transaction environment. Concurrency situation is not desirable for time dependent and time critical large database applications; it must be efficiently controlled and managed to ensure consistency of database system. The time aspect of data can be easily represented by temporal database, it allows you to associate time element with data through temporal validity support. Concurrency control mechanism elevates to a new height when it is implemented on temporal database especially for multiuser distributed transaction environment and it requires a special treatment. For consistency requirement to be true different user sessions of a distributed transaction running simultaneously must produce meaningful and consistent results otherwise it leaves database into inconsistent state. Traditionally timestamp and locking based approaches are used to encounter the concurrency problem. This research study proposes an efficient concurrency algorithm which is a mixture of both timestamp and locking approach suitable for temporal database environment where more than one users of distributed transaction tries to access the common resource. The scope of research involves design, implementation, experimental study and performance analysis of proposed algorithm in comparison with pessimistic and optimistic concurrency control mechanisms. The proposed algorithm is implemented through trigger using Oracle 12c which supports temporal database consistency through temporal validity support and efficient locking mechanism. Concurrency and locking situation is graphically represented in the experiment with the help of Oracle 12c enterprise manager.
Antibody–Drug Conjugates—A Tutorial Review (2021)

Antibody-drug conjugates (ADCs) are a family of targeted therapeutic agents for the treatment of cancer. ADC development is a rapidly expanding field of research, with over 80 ADCs currently in clinical development and eleven ADCs (nine containing small-molecule payloads and two with biological toxins) approved for use by the FDA. Compared to traditional small-molecule approaches, ADCs offer enhanced targeting of cancer cells along with reduced toxic side effects, making them an attractive prospect in the field of oncology. To this end, this tutorial review aims to serve as a reference material for ADCs and give readers a comprehensive understanding of ADCs; it explores and explains each ADC component (monoclonal antibody, linker moiety and cytotoxic payload) individually, highlights several EMA- and FDA-approved ADCs by way of case studies and offers a brief future perspective on the field of ADC research.
Some future directions for repetitive pulsed power (2002)

Repetitive pulsed power has been pursued at a moderate level for decades, yet in a sense it is still a young and growing discipline. This implies that it is still on the fast portion of its growth curve. The 1990s were a relatively quiet decade, but customer interest is growing again, and with it comes new demands on the technology. Orders of magnitude advances will be needed over the next ten years. Fortunately, there is the potential for improvements of that order because of the relative immaturity of the technology. This paper discusses some of that potential. It does not attempt to provide a complete overview of the possibilities. Rather it attempts to identify a few areas where large growth seems likely over the next decade and to highlight the drivers for substantial breakthroughs.
A Method for Evaluating Vestibular Control of Posture (1978)

Tests that measure the patient's ability to control his posture generally have failed to yield clinically useful information about vestibular function. The primary reason for this failure is that postural control does not depend on vestibular function when visual and proprioceptive cues are available. To test vestibular function, one should use a procedure that forces the patient to rely on vestibular cues by eliminating cues from these other sensory systems. Such a procedure is described. Vision is eliminated by eye closure, and proprioceptive cues are minimized by rotating the supporting surface to null changes in ankle angle. Data are presented which show that postural responses are complex, but that they appear to conform to the pattern originally observed by Nashner. A method potentially capable of separately evaluating semicircular canal and otolith function is described.
Fos proteins can act as negative regulators of cell growth independently of the fos transforming pathway. (1995)

The proto-oncogene c-fos is known to be an important positive regulator of cell growth and notably of the G0/G1 transition. However, we observed that v-fos or c-fos-transformed rat-1 fibroblasts paradoxically had a low growth rate as compared to control untransformed rat-1 cells. We determined that this slow growth mainly reflects an increase of the G1 phase of the cell cycle (up to fourfold). In addition, the G0 --> S progression of serum-starved fos-expressing rat-1 cells refed with serum was found to be also delayed as compared to rat-1 cells. The delayed G0 --> S progression in fos-expressing cells was accompanied by the inappropriate levels or kinetics of expression of several cell cycle-regulated genes (cyclin D1, cdc2, cdk2, cdk4 and rb). Furthermore, a clear uncoupling of the pRb hyperphosphorylation with the entry into S phase was found in these fos-expressing rat-1 cells. Interestingly, the effect of the Fos proteins on the cell cycle was independent of the fos transforming pathway, indicating that the effector genes for Fos proteins are likely to be different for each process. In conclusion, our results indicate that Fos proteins may act as negative regulators of cell growth in some cell types, independently of the fos transforming pathway.
Upper bound to the pressure in an elementary vacuum system (1977)

A vacuum system consisting of a volume V, a pump with speed S, and a surface area A on which there are initially adsorbed n (0) molecules in a first-order desorption state is considered and discussed. The essential result is that Pmax=1.146×10−5 A/St Torr is expected to provide a reasonably accurate estimate for the value the pressure should be strictly less than t seconds after the pumping has started, given that the pressure in the system is due to an adsorbed surface phase. Experimental tests of this relation have been performed and comparisons are made between this result and the pressure measured in an elementary vacuum system.
Studies on the Formation of Transfer Ribonucleic Acid-Ribosome Complexes (1972)

Chloramphenicol inhibits binding of aminoacyl-oligonucleotides to ribosomes from Escherichia coli.These aminoacyl-oligonucleotides, C-A-C-C-A(Phe), C-C-A(Phe), C-C-A(Lys), C-C-A(Ser), and C-C-A(Leu), represent the aminoacyl
Marketing: A key ingredient for educational fundraising success (1993)

Abstract Marketing provides student affairs professionals with some of the most effective strategies, techniques, and actions for success. This chapter, written for professionals without a marketing background, provides a design for the development of a strategic marketing approach to educational fundraising.
One SPE (August 2003) (2003)

President's column - No abstract available.
Rejection of Narrow-Band Interference in PN Spread-Spectrum Systems Using Transversal Filters (1982)

In the presence of narrow-band interference, the performance of PN spread-spectrum communication systems can he improved by using various interference rejection filters. In this paper, both prediction error filters and transversal filters with two-sided taps are used and the performance of each is analyzed. Analytic expressions for the signal-to-noise ratio improvement factors are obtained. If the frequency of the jamming tone is near the carrier frequency of the spread-spectrum signal, the performance of the transversal filter with two-sided taps is better than that of the prediction error filter with the same number of taps.
A 2.5Gb/s/ch 4PAM inductive-coupling transceiver for non-contact memory card (2010)

A 2.5 Gb/s/ch 4PAM inductive-coupling link is developed for non-contact memory cards. The data rate is 12.5x higher than that of a commercial memory card. By using automatic gain and phase control (AGPC), a communication range from 0.5 to 1 mm is achieved, which is 10X of that without AGPC. BER <10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-12</sup> operation is confirmed at a data-rate of 2.5 Gb/s.
Non-responders to hepatitis B vaccination: a review. (2003)

Hepatitis B virus (HBV) infection is a major public health issue throughout the world and vaccination of those at risk is the main method of containment. Of healthy vaccinees, 5-10% fail to mount an adequate antibody response. The antibody levels of an unknown further fraction of vaccinees fall considerably over time rendering them at a potential risk of infection. The scope of this article is to review the factors that might influence the immune response to HBV vaccination, to review the methods used to overcome the problem of poor response and to discuss what possible guidelines are available or needed in treating these vaccinees.