gebhart/patrepeval huggingface dataset:
Aberrant Expression of CD19 as a Marker of Monocytic Lineage in Acute Myelogenous Leukemia (1997)

Immunophenotypic analysis plays a critical role in the diagnosis and classification of acute leukemia. Certain characteristic immunophenotypic patterns have emerged that aid in the classification of acute myelogenous leukemia (AMD. We describe a unique pattern of expression of CD19, a B cell-associated cell surface antigen, in cases of AML. We reviewed 59 cases of de novo AML to determine the pattern of CD19 expression in cases of AML using three different CD19 monoclonal antibodies, including B4 (Lytic), B4 89B (Coulter, Miami, Fla) and SJ25-C1 (GenTrak, Plymouth Meeting, Pa). We confirmed the known relationship between CD19 expression and t(8;21)-positive AML M2; in these cases, CD19 was detected with all three antibodies. We also found a unique pattern of CD19 expression in cases of AML with a substantial monocytic-monoblastic component. In 6 of 12 cases of AML M4 or M5, CD19 expression was evident only with the B4 (Lytic) antibody; CD19 expression was not observed using B4 89B or SJ25-C1. We did not observe any recurring chromosomal abnormalities in these cases of CD19-positive AML M4/M5; furthermore, none of these cases demonstrated a t(8;21). Using CDUb, CD14, and other myeloid markers, we found that AML M4 and AML M5 were characterized by dual populations of blasts. With the exception of a case of AML M4 eo, cases of AML M4 were associated with one population of blasts lacking both CD11b and CD14 and a second population with one or both of these antigens. Cases of AML M5 also had dual populations of blasts, but in contrast with AML M4, each population expressed CD11b , CD14, or both. Our findings suggest that specific immunophenotypic patterns, including the unique pattern of CD19 expression with the B4 (Lytic) monoclonal antibody, may prove useful in classifying cases of AML M4 and M5.
A new method for astrometric observations of asteroids (1992)

In this paper we propose a new method for photographic astrometric observations of asteroids. We discuss its advantages and disadvantages and compare them to the advantages and disadvantages of the classical photographic methods. The new method is best suited for observations on a spot where no CCD cameras, blink or stereo comparators are available and when a fast detection of unknown objects is required.
Cross-organisational workflow management and co-ordination (1999)

The increasing deployment of Workflow Management Systems (WfMSs) and other co-ordination and process support systems on the one hand and the proliferation of cheap networking, namely the Internet, on the other hand raises the issue of how to connect these systems across organisational boundaries. Current WfMSs do not provide suitable means for cross-organisational connections. The workshop "Cross-Organizational Workflow Management and Co-ordination" at the International Joint Conference on Work Activities Coordination and Collaboration, San Francisco, February 22 - 25, 1999 provided a forum to discuss workflow management and co-ordination in situations in which processes span multiple independent organisations. The workshop helped the ca. 30 participants understand the key problems and clarified ways in which existing products and prototypes as well as current projects contribute to enable cross-organisational workflow execution.
Magneto-optical recording. (1987)

This paper is a review article for magneto-optical (MO) recording. Principles of writing (erasing) and reading and an outline of a MO recording apparatus are described firstly. Secondly, recording media (including material requirements and properties of rare earth-transition metal amorphous films), methods of film preparation, and the construction and properties of the MO disk are illustrated shortly. Lastly, future problems to be solved for practical use are discussed.
Using Multiversion Web Servers for Data-Based Synchronization of Cooperative Work (2000)

In this paper a new architecture for a multiversion Web server is proposed. This architecture is of three-tier type and consists in using an interpreter of a query language as a gateway for the server, specialized object-oriented multiversion database of resources as an engine, and an XML wrapper as a gateway for data repositories. The database-based server engine is capable of maintaining resources, their versions, and their meta-data. The engine performs also configuration management and consistency checking. The XML wrapper allows storing both data and meta-data across many repositories. Moreover, it performs caching and request redirecting for resources and their meta-data from mono-and multiversion servers. The proposed multiversion Web server may be used as generic information exchange tool for cooperative work in the integrated processes of development, production, and maintenance.
Occipital Nerve Electrical Stimulation via the Midline Approach and Subcutaneous Surgical Leads for Treatment of Severe Occipital Neuralgia: A Pilot Study (2005)

Persistent occipital neuralgia can produce severe headaches that may not be controllable by conservative or surgical approaches. We describe a case series of 6 patients who had chronic headaches over an average of 4.9 yr who underwent occipital nerve electrical stimulation lead implantation using a modified midline approach. The patients had received conservative and surgical therapies in the past including oral antidepressants, membrane stabilizers, opioids, occipital nerve blocks, and radiofrequency ablations. Significant decreases in pain visual analog scale (VAS) scores and drastic improvement in functional capacity were observed during the occipital stimulation trial and during the 3-mo follow-up after implantation. The mean VAS score changed from 8.66 +/- 1.0 to 2.5 +/- 1.3 whereas pain disability index improved from 49.8 +/- 15.9 to 14.0 +/- 7.4. Our midline approach has several advantages compared with the submastoid approach used elsewhere. There is only one small midline incision over the upper neck and the strain on the lead extension occurs only with flexion and is minimal with lateral flexion and rotation, which contributes to overall stability of this system.
Formation and electronic properties of palladium hydrides and palladium-rhodium dihydride alloys under pressure (2017)

We present the formation possibility for Pd-hydrides and Pd-Rh hydrides system by density functional theory (DFT) in high pressure upto 50 GPa. Calculation confirmed that PdH<sub>2</sub> in face-centered cubic (fcc) structure is not stable under compression that will decomposition to fcc-PdH and H<sub>2</sub>. But it can be formed under high pressure while the palladium is involved in the reaction. We also indicate a probably reason why PdH<sub>2</sub> can not be synthesised in experiment due to PdH is most favourite to be formed in Pd and H<sub>2</sub> environment from ambient to higher pressure. With Rh doped, the Pd-Rh dihydrides are stabilized in fcc structure for 25% and 75% doping and in tetragonal structure for 50% doping, and can be formed from Pd, Rh and H<sub>2</sub> at high pressure. The electronic structural study on fcc type Pd <sub>x</sub> Rh<sub>1-x</sub>H<sub>2</sub> indicates the electronic and structural transition from metallic to semi-metallic as Pd increased from x = 0 to 1.
Intraoperative measurement of lower esophageal spincter pressure. (1978)

The lower esophageal sphincter pressure has been measured intraoperatively in 200 patients with gastroesophageal reflux and in three patients with achalasia. Lower esophageal sphincter pressure is measured before and during repair. Calibrating the cardia during performance of the median arcuate posterior gastropexy allows a sphincter pressure between 50 and 57 mm. Hg to be obtained at operation. The postoperative pressures have ranged between 15 and 25 mm. Hg, or approximately half of the intraoperative pressure. No patient with a spincter pressure of 15 mm. Hg or greater has reflux according to postoperative pH and pressure studies. Correction of reflux correlates well with relief of symptoms. Three patients with achalasia had intraoperative manometrics during myotomy. The lower esophageal sphincter pressure was lowered and the length of the lower esophageal sphincter was shortened. Dysphagia was corrected without producing reflux. This is the first report of measurement of lower esophageal sphincter pressure in anesthetized patients. Intraoperative measurement of sphincter pressure is a safe, simple, and reliable technique which allows the surgeon, for the first time, to determine the status of the lower esophageal sphincter during the operation. This technique should be standard for all operations on the gastroesophageal junction.
A NEW SAMPLING SCHEME FOR THE RING POSITRON CAMERA (1982)

Cho, Z. H.; Hong, K. S.; Ra, J. B.; Lee, S. Y.; Hilal, S. K.; Correll, J. Author Information
A Glycosyltransferase Involved in Biosynthesis of Triglycosylated Glycopeptidolipids in<i>Mycobacterium smegmatis</i>: Impact on Surface Properties (2005)

The cell envelope of mycobacteria is a complex structure that plays an important role in the interactions of the cell with its environment and in the protection against the antimicrobial activity of the immune system. Glycopeptidolipids (GPLs) are species- or type species-specific glycolipids that are present at the surface of a number of mycobacteria and that are characterized by a high variability in glycosylation patterns. These GPLs possess various biological activities that depend mostly on the sugars capping the core molecule. In Mycobacterium smegmatis, the GPL core can be substituted by either two or three deoxyhexoses. In this study, we show that Gtf3 is a glycosyltransferase responsible for the synthesis of the triglycosylated GPLs. Biochemical analysis of these molecules, with a combination of mass spectrometry and chemical degradation methods, has shown that they contain three deoxyhexose moieties. The presence of the triglycosylated GPLs is associated with cell surface modifications that lead to a decrease in sliding motility as well as a modification in cellular aggregation and colony appearance on Congo red. Phylogenetic analysis indicated that Gtf3 is a member of a yet-uncharacterized glycosyltransferase family conserved among the mycobacteria.
Mesoporous Metal–Organic Frameworks with Size‐, Shape‐, and Space‐Distribution‐Controlled Pore Structure (2015)

Mesoporous Metal–organic frameworks (meso-MOFs) with size-, shape-, and space-distribution-controlled mesopores are obtained by a facile encapsulation and selective etching strategy of metal nanoparticles. Hierarchical or functionalized meso-MOFs are achieved by the above strategy. Interestingly, the functional meso-MOFs display higher catalytic activity originating from the mesopores existing in the MOFs, as well as good selectivity due to protection of the micro­porous frameworks.
Hong Kong (1996)

Essay| September 01 1996 Hong Kong: The Year Before Living Dangerously Frank Ching Frank Ching Frank Ching, senior editor of the Far Eastern Economic scheme, special administrative regions could be Review, opened The Wall Street Journal’s bureau in Beijing in established that would allow systems and lifestyles 1979 after the norm alization of Sino-American relations. He different from those in mainland China, with the has been writing about Hong Kong and China for more than two decades. Search for other works by this author on: This Site PubMed Google Scholar Current History (1996) 95 (602): 272–276. https://doi.org/10.1525/curh.1996.95.602.272 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Frank Ching; Hong Kong: The Year Before Living Dangerously. Current History 1 September 1996; 95 (602): 272–276. doi: https://doi.org/10.1525/curh.1996.95.602.272 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentCurrent History Search This content is only available via PDF. © 1996 by The Regents of the University of California1996 Article PDF first page preview Close Modal You do not currently have access to this content.
Sucrose-Indole-3-Acetic Acid Interactions on Root Regeneration by Pinus lambertiana Embryo Cuttings (1973)

Interactions affecting root formation by IAA and sucrose, supplied to Pinus lambertiana embryo cuttings through their cotyledons, were explored. The sucrose optimum for rooting and dry weight increase is approximately 8 %. Osmotic substitutes for sucrose, applied alone or concomitantly with sucrose, were unable to duplicate its effects on regeneration. One μM IAA increased the number of roots per cutting with all sucrose concentrations. However, with suboptimal sucrose concentrations it only increased the total number of cuttings forming roots. Because IAA accumulates at the site of root formation, the possibility that it mobilizes sucrose or its derivatives to the site of root formation was explored. No evidence was found for hormone-directed transport of sucrose in this system. IAA had no effect on either the basal accumulation or transport of label derived from U-14C-sucrose.
Structure and function of the divalent anion/Na+ symporter from Vibrio cholerae and a humanized variant (2017)

Integral membrane proteins of the divalent anion/Na<sup>+</sup> symporter (DASS) family translocate dicarboxylate, tricarboxylate or sulphate across cell membranes, typically by utilizing the preexisting Na<sup>+</sup> gradient. The molecular determinants for substrate recognition by DASS remain obscure, largely owing to the absence of any substrate-bound DASS structure. Here we present 2.8-Å resolution X-ray structures of VcINDY, a DASS from Vibrio cholerae that catalyses the co-transport of Na<sup>+</sup> and succinate. These structures portray the Na<sup>+</sup>-bound VcINDY in complexes with succinate and citrate, elucidating the binding sites for substrate and two Na<sup>+</sup> ions. Furthermore, we report the structures of a humanized variant of VcINDY in complexes with succinate and citrate, which predict how a human citrate-transporting DASS may interact with its bound substrate. Our findings provide insights into metabolite transport by DASS, establishing a molecular basis for future studies on the regulation of this transport process.
A new orthogonal transform for signal coding (1988)

The authors propose an orthogonal, unitary transformation called the modified Hermite transformation (MHT) and its extension, which is called the modular modified Hermite transformation (MMHT). The MHT algorithm, which is an efficient algorithm, is explained and explored. The MHT is compared to the discrete cosine transform (DCT) for various AR(1) input signal source models using the performance criterion of gain over PCM, denoted by /sup N/G/sub TC/. The MHT algorithm requires only 2N real multiplications or divisions for a transformation of a signal block of N samples. It is also used for the inverse transformation, IMHT, and makes this new transform attractive. It is efficient computationally and comparable to the DCT for AR(1) source models with positive correlation coefficients, it is somewhat better than the DCT for negative correlation coefficients.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Remotely sensed reflectance and its dependence on vertical structure: a theoretical derivation (1982)

An exact expression for the remotely sensed reflectance (RSR, upwelling radiance divided by downwelling scalar irradiance) just beneath the surface of the ocean is derived from the equation of radiative transfer. It is shown that the RSR at a given depth in the ocean depends only on the inherent optical properties, the attenuation coefficient for upwelling radiance, and two shape factors that depend on the radiance distribution and volume scattering function. The shape factors are shown to be close to unity. An exact expression for the RSR just beneath the surface as a function of the vertical structure of inherent and apparent optical properties is derived. This expression is solved for an N-layered system, which presents the possibility of inverting remotely sensed reflectance data to obtain the vertical structure of chlorophyll in the ocean.
How to Cope with some of the Challenges Associated with Laboratory Measurements on Gas Shale Core Samples (2014)

Abstract Routine lab characterization of conventional cores is often limited to geology, petrophysics, and mineralogy. With gas shale plays, however, geochemistry and rock-mechanic are key parameters to characterize as well. In this paper, we present several innovative techniques which allow coping with challenges associated with lab characterization on gas shale core samples. Such alternative techniques need addressing the following issues: Complex lab measurements, potentially to the threshold of what routine lab devices can characterize.Potentially high vertical variability of mineralogy and organic content. Two innovative and worldwide unique measurement devices have then been developed in-house: A transient permeameter, the Step-Decay device, capable of measuring permeability down to the nanoDarcy, at different levels of confining stress and connate water content.A high-resolution geochemical core logging tool, the LIPS device (Laser Induced Pyrolysis System), designed to measure the organic matter content on a continuous centimeter scale basis. So as to cope with the variability issue, a comprehensive set of high resolution core logs has been systematically run: CT-scan and spectral GR logs for petrophysics, scratch-test log for rock-mechanic, and LIPS log for organic matter quantification; we combine all these techniques together for a better core characterization. We present the analysis workflow applied to a gas shale case-study, insisting on the challenges we faced and the way we coped with them. Benchmarking with alternative techniques and lab results is presented as well.
Comparable efficacy of contingency management for cocaine dependence among African American, Hispanic, and White methadone maintenance clients. (2009)

Cocaine use is a significant problem among methadone maintenance clients. Contingency management (CM) is a reinforcement-based approach with demonstrated efficacy for reducing cocaine use. This study examines whether the efficacy of CM treatment for cocaine-dependent individuals receiving methadone maintenance for opioid dependence differs by ethnicity. Participants were 191 African American, Hispanic, and White cocaine-dependent methadone maintenance clients, randomly assigned to standard methadone treatment or standard methadone treatment plus CM for 12 weeks. Hispanic participants were younger, less educated, and reported fewer years of cocaine use than did African American and White participants and reported fewer years of heroin use than did African American participants. African American participants were less likely to report a history of psychiatric symptoms or treatment in comparison with Hispanic and White participants. While CM was associated with longer duration of continuous cocaine abstinence and a greater proportion of submitted urine samples negative for cocaine, ethnicity was not related to treatment outcomes, and there was no significant interaction between treatment and ethnicity. CM appears to be an efficacious treatment for cocaine dependence among methadone maintenance clients, regardless of ethnicity. (PsycINFO Database Record (c) 2009 APA, all rights reserved).
Comprehensive whole-genome sequencing of an early-stage primary myelofibrosis patient defines low mutational burden and non-recurrent candidate genes (2013)

In order to identify novel somatic mutations associated with classic BCR/ABL1-negative myeloproliferative neoplasms, we performed high-coverage genome sequencing of DNA from peripheral blood granulocytes and cultured skin fibroblasts from a patient with MPL W515K-positive primary myelofibrosis. The primary myelofibrosis genome had a low somatic mutation rate, consistent with that observed in similar hematopoietic tumor genomes. Interfacing of whole-genome DNA sequence data with RNA expression data identified three somatic mutations of potential functional significance: i) a nonsense mutation in CARD6, implicated in modulation of NF-kappaB activation; ii) a 19-base pair deletion involving a potential regulatory region in the 5'-untranslated region of BRD2, implicated in transcriptional regulation and cell cycle control; and iii) a non-synonymous point mutation in KIAA0355, an uncharacterized protein. Additional mutations in three genes (CAP2, SOX30, and MFRP) were also evident, albeit with no support for expression at the RNA level. Re-sequencing of these six genes in 178 patients with polycythemia vera, essential thrombocythemia, and myelofibrosis did not identify recurrent somatic mutations in these genes. Finally, we describe methods for reducing false-positive variant calls in the analysis of hematologic malignancies with a low somatic mutation rate. This trial is registered with ClinicalTrials.gov (NCT01108159).
Highly Efficient Hybrid Solar Cells Based on an Octithiophene–GaAs Heterojunction (2005)

Abstract We report a new type of hybrid heterojunction solar cell based on rod‐like octithiophene (8T) as the organic p‐type semiconductor and GaAs(111) as the inorganic n‐type semiconductor. By using a semitransparent gold layer as the front contact deposited onto the 8T films, solar‐energy conversion efficiencies of up to 4.2 % could be obtained. The reduction in the contact resistance at the Au/8T interface induced by iodine doping is found to be a very crucial factor for the high efficiency. Furthermore, we demonstrate that hybrid solar cells can be successfully used to investigate the photovoltaic properties of organic semiconductors in detail. By means of external quantum efficiency (EQE) measurements, the influence of film morphology on the photocurrent collection length in 8T films is studied. The results show that, in hybrid solar cells using highly ordered microcrystalline 8T films, an active contribution of the organic‐layer semiconductor to the total photocurrent exists. A very large photocurrent collection length of up to 100 nm has been estimated from EQE measurements, indicating that exciton diffusion is very efficient in microcrystalline 8T. On the other hand, the use of nanocrystalline 8T leads to high photocurrent losses in the organic part of the hybrid solar cell. The strong influence of the film morphology on the photocurrent collection in 8T is attributed to a reduction in the exciton diffusion length due to a high trap density in nanocrystalline 8T films. Thus, our results reveal the importance of high crystalline order for obtaining efficient photocurrent collection in 8T films.
Low Overhead and Fast Reaction Adaptive Clocking System for Voltage Droop Tolerance (2019)

Variation in on-chip power supply continues to be a major challenge to limit circuit performance. To mitigate the impact of high-frequency voltage droop, a novel all-digital adaptive clock system is proposed. The adaptive clock system is composed of a droop detector and an adaptive clock generator, which directly stretch the clock period when the circuit suffers from the supply voltage droop. The droop detector circuit detects the VDD droop and the digital adaptive clock generator circuit selects the stretched clock to prevent timing-margin failures. The response time for droop detection and clock stretch can be as fast as one cycle. The whole scheme is used on a test circuit under SMIC 40nm CMOS process with a layout area of 900um*1100um. Postlayout simulation results demonstrate power reductions are 7% at 1.1V and 15% at 0.7V for a 10% VDD droop, respectively.