gebhart/patrepeval huggingface dataset:
Correction of morphofunctional disorders with asialoerythropoietin and selective inhibitor of arginase II KUD975 in cases of ischemic kidney damage in the experiment (2018)

Introduction : Acute kidney injury (AKI), which is based on ischemic-reperfusion damage, is a widespread life-threatening condition and remains a serious public health problem with a high mortality rate among patients. Despite significant advances in various areas of medicine, the prevention and correction of ischemic-reperfusion kidney damage are still far from being at the desired level. Pharmacological preconditioning and the use of endothelioprotectors are promising areas in this field, therefore the purpose of this study was to analyze the nephroprotective properties of asialoerythropoietin and selective inhibitor of arginase II KUD975 in ischemic kidney damage in the experiment. Materials and methods : The study was performed on 260 white adult male Wistar rats, each weighing 180-220 g. Ischemic-reperfusion damage was simulated by applying a clamp on the renal leg for 40 minutes. To determine a degree of correction caused by morphofunctional disorders traditional functional, biochemical and morphological criteria were used. Results and discussion : When administering asialoerythropoietin and selective inhibitor of arginase II KUD975, there is observed an improvement in the glomerular filtration and microcirculation in the kidneys, decrease in the concentration of creatinine and urea, a decrease in fractional excretion of sodium and improvement in the histological pattern at different periods. The most pronounced nephroprotective effects are observed in the combined use of the test pharmacological agents, which are superior to such used in a monotherapy. The use of glibenclamide and L-NAME against the background of the correction of the pathology caused by asialoerythropoietin completely eliminates its positive effects. When glibenclamide and L-NAME are used against the background of correction of the pathology caused by the selective inhibitor of arginase II KUD975, its positive effects are completely eliminated by L-NAME. Glibenclamide does not eliminate positive effects. Conclusions : The results of the experiment prove the presence of pronounced nephroprotective properties of asialoerythropoietin and selective inhibitor of arginase II KUD975 in ischemic kidney damage in the experiment. The most pronounced effects are observed in the combined use of these pharmacological agents. The leading role in causing the positive effects from asialoerythropoietin is played by the activation of K+ATP channels and the activation of eNOS. The leading role in causing the positive effects from the selective inhibitor of arginase II KUD975 is played by the activation of eNOS.
Calibration of Video-Oculographical Eye-Tracking System (2006)

Video-oculography (VOG) is the most suitable eye tracking method in Human Computer Interaction. The precise mapping from image co-ordinates to computer monitor screen co-ordinates in real time is necessary for efficient computer control. During this study, the calibrations techniques were investigated. It was noticed that, there is no significant difference between a mapping with developed model, describing eye image formation process in the sensor, and with polynomial calibration. Polynomial calibration model do not allow a free head motion and requires frequent recalibration. A model based mapping is tolerant to head motions. An improved model could take an advantage over polynomial mapping. Ill. 7, bibl. 8 (in English, summaries in English, Russian, Lithuanian).
Phase-Change Materials for Electronic Memories (2008)

The materials used in rewritable CDs and DVDs also show promise as electronic memories systems.
Evaluation of Skin Photo-stress Using Catalase (2010)

In order to develop an evaluating method of photo-stress of skin, we have been investigating a methodology to analyse catalase activity derived from stratum corneum (skin catalase activity) as a biomarker. The objective is to demonstrate the usefulness of skin catalase activity as an index of photo-stress by compairing the cheek and the upper arm in 61 female adults. The stratum corneum was collected by tape stripping, concentrating stratum corneum sample solution and using a fluorescent substrate of skin catalase activity. The skin catalase activity ranged between 1.18 and 223 U/cm2 in all of the stratum corneum samples in the subjective evaluation. It was indicated that this analysis method had a sufficient range for the analysis of skin catalase activity. The significant correlation was observed between the skin catalase activity /total protein (TP) ratio and the skin color parameter (skin color: a*, r =0.54; b*, r = -0.44). Therefore, it was considered that the skin catalase activity /TP ratio might be a useful index of the skin condition for humans.
Adaptive multiple subtraction using regularized nonstationary regression (2008)

Abstract Stationary regression is the backbone of seismic data-processing algorithms including match filtering, which is commonly applied for adaptive multiple subtraction. However, the assumption of stationarity is not always adequate for describing seismic signals. I have developed a general method of nonstationary regression and that applies to nonstationary match filtering. The key idea is the use of shaping regularization to constrain the variability of nonstationary regression coefficients. Simple computational experiments demonstrate advantages of shaping regularization over classic Tikhonov's regularization, including a more intuitive selection of parameters and a faster iterative convergence. Using benchmark synthetic data examples, I have successfully applied this method to the problem of adaptive subtraction of multiple reflections.
Building a High-Quality Mobile Telemedicine System using Network Striping over Dissimilar Wireless Wide Area Networks (2005)

This paper describes an approach to building a high-quality mobile telemedicine system that overcomes the limitations of individual public wireless data networks. Public wireless data channels do not have the capacity to handle the high-bandwidth video needed for applications such as remote evaluation of trauma and stroke patients. Network striping allows us to aggregate multiple physical channels to meet the bandwidth requirements for the video. We have developed flexible network-striping software middleware, and are building a telemedicine system using that middleware. Our approach uses existing communications infrastructure and conventional-off-the-shelf components, making the system easy to deploy.
n Tuning PI Controllers for Integrating Plus Time Delay Systems (2010)

Some analytical results concerning PI controller tuning based on integrator plus time delay models are worked out and presented. A method for obtaining PI controller parameters, K p = k , and, T i = , which ensures a given prescribed maximum time delay error, d max , to time delay, , ratio parameter = d max , is presented. The corner stone in this method, is a method product parameter, c = . Analytical relations between the PI controller parameters, T i , and, K p , and the time delay error parameter, , is presented, and we propose the setting, = c a ( + 1), and, = a +1 , which gives, T i = c a ( + 1) , and, K p = a (+1)k , where the parameter, a, is constant in the method product parameter, c = . It also turns out that the integral time, T i , is linear in, , and the proportional gain, K p , inversely proportional to, + 1. For the original Ziegler Nichols (ZN) method this parameter is approximately, c = 2.38, and the presented method may e.g., be used to obtain new modified ZN parameters with increased robustness margins, also documented in the paper.
Observation of chromatic effects near a white-light vortex (2003)

Using a spatial light modulator to modify the phase of a light beam we create a spatially coherent, white-light beam containing an optical vortex. All the spectral components are helically phased; hence the beam carries an orbital angular momentum that is an integer multiple of ℏ per photon. A low-dispersion prism, positioned after the modulator, ensures that the vortices associated with each spectral component are co-axial. In addition, deliberate introduction of slight spectral dispersion means that the vortices associated with each wavelength no longer overlap. Subsequent examination near the beam axis reveals the chromatic effects predicted by Berry (2002 New J. Phys. 4 66; 74).
Data partition and parallel evaluation of Datalog programs (1995)

Parallel bottom-up evaluation provides an alternative for the efficient evaluation of logic programs. Existing parallel evaluation strategies are neither effective nor efficient in determining the data to be transmitted among processors. In this paper, we propose re different strategy, for general Datalog programs, that is based on the partitioning of data rather than that of rule instantiations. The partition and processing schemes defined in this paper are more general than those in existing strategies. A parallel evaluation algorithm is given based on the semi-naive bottom-up evaluation. A notion of potential usefulness is recognized as a data transmission criterion to reduce, both effectively and efficiently, the amount of data transmitted. Heuristics and algorithms are proposed for designing the partition and processing schemes for a given program. Results from an experiment show that the strategy proposed in this paper has many promising features.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Simple and Efficient Approach to the Synthesis of 2-Phenylquinazolines via sp<sup>3</sup> C−H Functionalization (2010)

A facile and novel approach to the synthesis of 2-phenylquinazolines was developed via a tandem reaction following sp(3) C-H functionalization. Twenty-five examples of 2-phenylquinazolines were obtained from easily available 2-aminobenzophenones and benzylic amines with good to excellent yields.
RECENT PROGRESS ON PARTICLE IMAGE VELOCIMETRY IN CHINA (2006)

粒子图象 Velocimetry (PIV ) 乐器学上的最近的进步的新评论广泛地在纸被介绍。约 80 文学被引用。在 PIV 进展的各种各样的方面之中，现在的担心主要被放在先进算法和显微镜的 PIV 的进步上。注意明确地向对这些题目的国内研究人员的贡献被指导，它在整个讨论被强调。另外，在中国的 PIV 技术的多样的应用， e。g。，骚乱测量，水动力学，旋转流动，二阶段的流动，明确地被总结。
Towards development of autofocusing schemes for phase compensation of synthetic aperture sonars (2002)

This article is dedicated to the phase compensation problem associated with synthetic aperture sonar beamforming. Array movements during the time of synthesis and medium heterogeneity have to be compensated at a degree of accuracy of a fraction of wavelength to achieve the full resolution expected from theory. We present a phase noise correction scheme based on 2D correlations of conventional beam signals coming from adjacent pings. Successful compensation of ping to ping lateral displacement amplitudes up to 75 /spl lambda/ have been achieved by the proposed method on DUBM-42 actual sonar data (the DUBM-42 is a French Navy owned high resolution side looking imaging sonar at 400 kHz).
Spatial distribution of display sites of Grey Peacock-pheasant in relation to micro-habitat and predators during the breeding season (2018)

The destruction and fragmentation of forest in Southeast Asia is accelerating biodiversity loss, resulting in a range of management and conservation actions. For some species, a detailed understanding of microhabitat selection is critical for this, especially in the breeding season.
Epibatidine Analogs Synthesized for Characterization of Nicotinic Pharmacophores—A Review (2009)

In 1992 Daly and co-workers reported the isolation of a new natural product, epibatidine. Future studies showed that epibatidine was an nAChR ligand with analgesic potency 200-400 times greater than that of morphine. However, its potential as a new drug was limited by its toxic side effects, probably resulting from its activity at a number of nAChR subtypes. Epibatidine's unique structure and potent activity made it an ideal lead structure for the development of nAChR ligands with reduced side effects and better nAChR subtype selectivity. This review presents the synthetic methods we have used to synthesize a number of epibatidine agonists, antagonists, and mixed agonists/antagonists to better characterize the α4β2 nAChR pharmacophore and hopefully provide compounds that have potential for treating nicotine addiction.
Immunocytochemical detection of anti-müllerian hormone in Sertoli cells of various mammalian species including human. (1987)

An immunocytochemical method, based on the use of a polyclonal antibody raised against purified bovine anti-Müllerian hormone (AMH), was used to detect AMH in Sertoli cell cytoplasm of various mammalian species, including human. Immunopurification of antiserum by AMH-affinity chromatography, although not mandatory, leads to better results and increased sensitivity. In human testicular tissue, AMH is detectable up to 6 years of age. In rats, AMH production is initiated at 13 days post coitum, peaks between 15 and 17 days, and is no longer detectable 1 week after birth. The reaction is strongest in Sertoli cells of calves, sheep, goats, and pigs, species characterized by a high degree of development of the rough endoplasmic reticulum. It is fainter in human, rat, rabbit, and cat Sertoli cells, in which the rough endoplasmic reticulum is not as abundant. This correlation is not unexpected, in view of the localization of reaction product in this cytoplasmic organelle. Preliminary results indicate that there may be a relationship between the amount of immunoreactive AMH present in testicular biopsies of intersex patients and the degree of regression of the Müllerian duct on the ipsilateral side. This may help to elucidate whether persistence of Müllerian ducts results from lack of testicular production of AMH or from peripheral resistance of the Müllerian primordia to the hormone.
The Use of a Steering Shaping Function to Improve Human Performance in By-Wire Vehicles (2008)

The U.S. Army is examining evolutionary concepts for the command and control of military vehicles. Currently, there is a performance issue regarding vehicle control at higher speeds for some indirect vision, by-wire tactical vehicles. By-wire vehicles are those in which mechanical links between the driver and control devices are replaced by electronic or computerized signals. Specifically, an operator's ability to maintain reliable control of by-wire military vehicles while driving appears to be progressively compromised as vehicle speed increases. Several factors have been identified as possible sources of this difficulty, including lags in the system control loop, characteristics of the steering interface (such as its shaping function or lack of force feedback), inadequate visual display, and physical effects of vehicle motion on the operator (McDowell et al., 2007a). This report is a review of the current state of knowledge regarding the steering shaping function, which specifies the dynamic spatial relationship between steering input from the driver and vehicle heading direction. The overall goal of the review is to identify design parameters critical to improving current by-wire implementation in military tactical vehicles, thereby identifying design elements to optimize human-vehicle system performance for secure mobile operations. Through a review of general automotive literature related to variable gear ratio steering systems as well as steer-by-wire design and implementation, three main factors affecting steering control were identified. The primary factors of influence that were reviewed included the overall range of motion ( throw ) of the steering device, the steering shaping function, and modifications of the shaping function because of vehicle motion characteristics.
Erythromycin. VI. Degradation Studies<sup>1</sup> (1956)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTErythromycin. VI. Degradation Studies1Max V. Sigal Jr., Paul F. Wiley, Koert Gerzon, Edwin H. Flynn, U. Carol Quarck, and Ollidene WeaverCite this: J. Am. Chem. Soc. 1956, 78, 2, 388–395Publication Date (Print):January 1, 1956Publication History Published online1 May 2002Published inissue 1 January 1956https://doi.org/10.1021/ja01583a038RIGHTS & PERMISSIONSArticle Views219Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alertsclose Get e-Alerts
Rodent models of anxiety-like behaviors: are they predictive for compounds acting via non-benzodiazepine mechanisms? (2001)

An overview of the preclinical literature on the effects of the most studied clinically effective or putative non-benzodiazepine anxiolytics in existing animal models of anxiety-like behavior indicates that, with the exception of 5-HT1A agonists, these compounds display highly variable effects. Because these drugs have been shown (selective 5-HT reuptake inhibitors) or proposed (CCK(B) and CRF antagonists) to have a different spectrum of therapeutic activity in anxiety disorders than benzodiazepines, agents mainly used against generalized anxiety disorder, the screening of such compounds clearly requires the validation of new techniques that may model aspects of these conditions.
The chemistry of sulfilimines (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe chemistry of sulfiliminesThomas L. Gilchrist and Christopher J. MoodyCite this: Chem. Rev. 1977, 77, 3, 409–435Publication Date (Print):June 1, 1977Publication History Published online1 May 2002Published inissue 1 June 1977https://pubs.acs.org/doi/10.1021/cr60307a005https://doi.org/10.1021/cr60307a005research-articleACS PublicationsRequest reuse permissionsArticle Views2021Altmetric-Citations194LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Polyoxometalate-Based Layered Structures for Charge Transport Control in Molecular Devices (2008)

Hybrid organic-inorganic films consisted of molecular layers of a Keggin-structure polyoxometalate (POM: 12-tungstophosphoric acid, H(3)PW(12)O(40)) and 1,12-diaminododecane (DD) on 3-aminopropyl triethoxysilane (APTES)-modified silicon surface, fabricated via the layer-by-layer (LBL) self-assembly method are evaluated as molecular materials for electronic devices. The effect of the fabrication process parameters, including primarily compositions of deposition solutions, on the structural characteristics of the POM-based multilayers was studied extensively with a combination of spectroscopic methods (UV, FTIR, and XPS). Well-characterized POM-based films (both single-layers and multilayers) in a controlled and reproducible way were obtained. The conduction mechanisms in single-layered and multilayered structures were elucidated by the electrical characterization of the produced films supported by the appropriate theoretical analysis. Fowler-Nordheim (FN) tunneling and percolation mechanisms were encountered in good correlation with the structural characteristics of the films encouraging further investigation on the use of these materials in electronic and, in particular, in memory devices.
Effect of Acupuncture at Hsien-Ku (St-43) on the Pulse Spectrum and a Discussion of the Evidence for the Frequency Structure of Chinese Medicine (2000)

We investigated the pulse spectrum variation of the human radial artery when Hsien- Ku (St 43), an acupoint on the stomach meridian, was needled and compared the results with the acupuncture effects of two other acupoints, Tsu-San-Li (St-36) and Tai-Shih (K-3), reported previously. For Hsien-Ku, the harmonic proportions were redistributed: the second harmonic (C2) decreased, C3, C5, C6, C7, C8 and C9 increased, C3, C6 and C9 became the relative peaks to their neighboring harmonics and C2, C4 became the relative minimums. The phase angles of the 2nd harmonic (P2) and 5th harmonic (P5) decreased, propagating faster. These effects were similar to that of Tsu-San-Li which is also on the stomach meridian. A totally different pattern was found for Tai-Shih on the kidney meridian. These results strengthen the theory that a meridian can be classified according to its effects on the pulse spectrum, and that all the meridian related effects such as those caused by acupuncture or meridian specific herbs are frequency specific.
Optical fibre local access network software tools (1992)

Details are presented of a software package which combines the theoretical models developed in the course of a research programme with experimental data obtained from devices used in U.K. field trials of fibre in the local access network. This package could provide a rapid prototyping test-bed on which the early design and planning of the access network could be structured. The limits of optical network performance in the key areas of power budget and return loss can be assessed readily using the package as part of the design and planning process.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Fitness and cognition in the elderly (2016)

Higher V̇o2max is associated with better global cognitive function and with better performance in the cognitive domains of memory, executive function, and motor skills in the middle-aged and elderly. The association is not mediated by the presence of white matter lesions, lacunes, and brain atrophy.
Induction of forward mutation at the <i>yg</i>2 locus in maize by ethylnitrosourea (1985)

We analyzed the kinetics of mutation induction at the yg2 locus in Zea mays by N-ethyl-N-nitrosourea (ENU). ENU concentrations ranged from 0.1 to 10.7 mM and a linear, concentration-dependent response was observed for the induction of yg2 sectors in leaf 4 and leaf 5. For both leaf 4 and leaf 5 ENU exhibited one-hit kinetics consistent with either a point-mutational or chromosome-breakage mechanism of mutation induction. The mean induced mutation rate/mM ENU for the combined leaf 4 and leaf 5 data was 6.77 X 10(-4) mutations/locus/mM ENU. This value was used to compare the mutagenic effectiveness of ENU with ethyl methanesulfonate (EMS) and to calculate a rad equivalent for ENU. ENU was found to be 3.8-fold more effective than EMS. Based on their respective chemical reactivities with DNA, we propose that ENU predominantly induces point mutations at the yg2 locus. One rad of gamma radiation induced the same rate of mutation as an 8-hr exposure to a 6.71 X 10(-6) M concentration of ENU at 20 degrees C.