gebhart/patrepeval huggingface dataset:
HOST CELL REACTIVATION BY FIBROBLASTS FROM PATIENTS WITH PIGMENTARY DEGENERATION OF THE RETINA (1983)

Abstract –Cockayne syndrome (CS) is an autosomal recessive disease characterized by numerous clinical abnormalities including acute sun sensitivity and primary pigmentary degeneration of the retina. Cultured fibroblasts from CS patients are hypersensitive to ultraviolet (UV) radiation. Since host cell reactivation of irradiated virus is a useful probe to evaluate repair in different host cells, we studied such host cell reactivation in CS and in other diseases with retinal degeneration. The survival of UV‐irradiated Herpes simplex virus type 1 was determined in fibroblast lines from four normal donors. two patients with CS, one with both xeroderma pigmentosum (XP) and CS, and from several other patients with (Usher syndrome, olivopontocerebellar atrophy, retinitis pigmentosa) and without (XP, ataxia telangiectasia) primary pigmentary degeneration of the retina. The viral survival curves (log survival vs linear fluence) in all cell lines showed two components: a very sensitive initial component (not quantitated in this study) followed by an exponential, less sensitive component. The exponential component had greater sensitivity than normal in the case of the CS patients, the patient with both XP and CS. and the XP patient. We propose that patients with CS have defective repair of DNA which may be the cause of their retinal degeneration.
[Psychologic profile of vibration disease patients]. (2011)

The authors studied some psychologic state parameters in vibration disease patients. Findings are marked differences in patients, depending on the acting vibration type and the disease stage.
Total Corneal Power Estimation: Ray Tracing Method versus Gaussian Optics Formula (2010)

In eyes after refractive surgery, calculating posterior corneal power using the Gaussian formula and its paraxial assumptions introduces errors in the calculation of total corneal power. This may generate errors in intraocular lens power calculation when using the Gaussian formula after refractive surgery.
Syntheses of Benzophenone and Benzaldehyde Methyl Ethyl and Dimethyl Acetals by an Electrolytic Method (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSyntheses of Benzophenone and Benzaldehyde Methyl Ethyl and Dimethyl Acetals by an Electrolytic MethodB. Wladislaw and A. M. J. AyresCite this: J. Org. Chem. 1962, 27, 1, 281–282Publication Date (Print):January 1, 1962Publication History Published online1 May 2002Published inissue 1 January 1962https://pubs.acs.org/doi/10.1021/jo01048a503https://doi.org/10.1021/jo01048a503research-articleACS PublicationsRequest reuse permissionsArticle Views154Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
<title>Progress in ultrasound phase thermography</title> (2001)

Ultrasound Phase Thermography (UPT) is a non-destructive technique derived from Ultrasound Lock-In Thermography (ULT) which was established a few years ago. UPT provides defect selective imaging using thermal waves generated by elastic waves. The use of short ultrasound bursts instead of sinusoidal signals for excitation allows for faster measurements and better reproducibility as compared to ULT. However, the advantages of phase images are the same: recognition of defect depth and suppression of temperature gradients. Application of UPT to typical defects of aircraft materials and components provide specific information on their nature.
Protective and nonprotective monoclonal antibodies to Cryptococcus neoformans originating from one B cell. (1995)

Two immunoglobulin M monoclonal antibodies (mAbs) derived from the same B cell recognize different epitopes on the capsular polysaccharide of the pathogenic yeast, Cryptococcus neoformans. Their respective epitopes are located in spatially distinct regions of the capsule. Passive administration of one mAb prolonged survival whereas the other mAb did not. The results indicate that specificity is an important determinant of antibody efficacy against C. neoformans and that somatic mutations occurring during the antibody response can affect the protective efficacy of antibodies to C. neoformans.
Isolation and characterization of STAT3 and PY‐STAT3 signaling endosomes (2006)

Cytokine‐ and growth factor‐initiated STAT signaling transits from the plasma membrane to the nucleus. Until recently, STAT signaling has been viewed exclusively as a soluble cytosolic process. We have previously presented evidence for membrane‐associated STAT3 signaling through the cytoplasm [Shah et al (2005) The FASEB Journal 19, Abstract 209.9]. Using a detergent dissection approach to determine the relative magnitude of membrane‐associated versus free cytosolic PY‐STAT3 signaling, approximately 70 % of IL‐6‐activated cytoplasmic PY‐STAT3 was found to be associated with cytoplasmic vesicular elements suggesting that the membrane‐associated signaling is the major pathway. There was constitutive as well as an IL‐6‐enhanced association of cytoplasmic STAT3 and PY‐STAT3 with vesicular components positive for markers of the endolysosomal pathways [clathrin heavy chain (CHC), Rab5, Rab7, LAMP1, LAMP2 and EEA1]. To test whether significant amounts of STAT3 and PY‐STAT3 were associated with isolated endocytic organelles as predicted by the STAT3 signaling endosome model, early endosomes enriched for EEA1 and Rab5 were purified from IL‐6‐treated Hep3B cells [Aniento et al (1996) J. Cell. Biol. 133: 29‐41]. STAT3 complexed with CHC constitutively associated with this early endosome fraction. At 15 min after IL‐6, the majority of cytoplasmic PY‐STAT3 was associated with early endosomes, with the remainder in the late endosome and low‐density membrane fractions; there was little soluble PY‐STAT3. These data provide direct evidence in support of the STAT3 signaling endosome pathway. Supported by a Susan G. Komen Foundation dissertation award (MS) and NIH‐HL73301.
Effect of C-peptide on wound healing and microcirculation in diabetic mice. (2002)

Except for the significantly increased number of leukocytes adherent to venular endothelium in the C-peptide group no alteration was observed in wound healing and microcirculation. Neutrophil recruitment after C-peptide injection is of interest because it may reduce the risk of infection in diabetes mellitus.
A Th1-Recognized Peptide P277, When Tandemly Repeated, Enhances a Th2 Immune Response toward Effective Vaccines against Autoimmune Diabetes in Nonobese Diabetic Mice (2008)

Subunit immunogens containing tandemly repeated copies of T and B cell epitopes have been shown to be more immunogenic than the respective immunogen containing only a single copy of the sequence. To investigate whether the increased copies of the Th2-activated peptide sequence will enhance the Th2-like immune response, we compared the cytokine secreted in mice that inoculated with two immunogens containing one or six tandemly repeated copies of a Th2-activated peptide sequence P277. Immunization of mice with a 6xP277 fusion protein elicited much higher levels of Th2-type cytokines and lower Th1-type cytokines than with a fusion protein with one P277 peptide. The data of tandemly repeated peptide P277 potentiate the anti-inflammatory in NOD mice, most likely associated with a Th1 to Th2 cytokine shift specific for the autoimmune T cells, which suggested that application of multiple tandem repeats of a Th2-activated epitope is an efficient method to enhance the anti-inflammatory immune response by shifting the immune response from Th1-like to Th2-like. The subunit immunogens containing tandemly repeated copies of peptide P277 might be effective vaccines against autoimmune diabetes in NOD mice.
Dehydrogenation of 4,5-Disubstitued 9,10-Dihydrophenanthrenes (1987)

Dehydrogenation rates of four 4,5-disubstituted 9,l0-dihydrophenanthrenes to the corresponding phenanthrenes by 10% palladium on charcoal for the substituents, H, OCH3, F and CH3, appear to be related to the size of the substituents. The preparation of three new phenanthrenes, viz. 4,5-dichlorophenanthrene, 4,5-difluoro-phenanthrene and 4,5-bis( trifluoromethyl ) phenanthrene, is described. Treatment of mesitylene with either 10% palladium on charcoal at reflux or 2,3-dichloro-5,6- dicyano-1,4-benzoquinone gives an appreciable yield of mesityl(3',5'-xylyl)methane.
Using Visualization to Detect Plagiarism in Computer Science Classes (2000)

This paper introduces a number of general methods for visualizing commonality in sets of text files. Each visualization simultaneously compares one file in the set to all other files in the set. These visualizations, which can be comput-ed in O ¢¡¤£ time and space, are explained and then applied to the problem of detecting plagiarism in large computer science classes. A case study is presented and sample visualizations are provided. Finally, a new interactive tool that can be used to produce and manipulate these visualizations is presented. 1.
Synthesis and Characterization of (d)NTP Derivatives Substituted with Residues of Different Photoreagents (1995)

Chemical cross-linking agents having a photoactivable azido group are promising for the study of the spatial organization of biopolymers. We describe here a variety of (d)NTPs derivatives (6a, 6b, 7, 11, 12, 14, and 16) bearing the residues of three different photoreagents containing an aromatic azido group (1a, 2a, and 3a). These conjugates provide a wide choice of instruments to investigate nucleic acid-nucleic acid and nucleic acid-protein interaction. The synthesis of new photoreagent 2a has been also fulfilled. This compound is the most attractive for affinity modification of the nucleic acids.
Absence d'effet de l'incorporation d'un phosphopeptide du lait sur l'utilisation du calcium et du phosphore chez le jeune porc (1989)

Casein phosphopeptides are known to influence calcium absorption. A 50-day study was performed in 6-week old pigs fed either a control diet or a 5% casein phosphopeptide-containing diet (PP group). Both diets provided similar amounts of Ca (0.8%), P (0.5%), proteins, energy and vitamins. PP diet provided near 1/2 of total Ca, 1/3 of total P and 1/5 of proteins in the form of casein phosphopeptide. Ca and P excretion, absorption and retention were evaluated during a 10-day balance study. Bones were collected at slaughter to determine density, bending moment and bone mineral content. Calcium absorption and bone parameters (urinary hydroxyproline included) were not influenced by the type of diet. P absorption, but not retention, was slightly higher in the control group. Urinary Ca was higher and urinary P lower in PP pigs than in controls. These changes might result from the different kinds of dietary phosphorus, inorganic versus phosphopeptide, rather than from the difference between dietary proteins.
Addition of polyethersulphone to epoxy resins (1983)

Abstract Phase separation of polyethersulphone from solution in epoxy resins has been studied as a function of polyethersulphone concentration, type of resin, and curing conditions. The resins chosen were a rapidly curing tetrafunctional and a trifunctional epoxy resin, hardened with either diaminodiphenylsulphone, or dicyandiamide. Fracture surfaces of some of the cured blends exhibited nodular features between 0.2μm and 6μm in diameter. Using X‐ray microanalysis and scanning electron microscopy these nodules were shown to contain high concentrations of polyethersulphone. Mechanical properties, including fracture energy, dynamic mechanical relaxation and creep, were studied for the same range of blend compositions. Dynamic mechanical spectra provided further evidence for phase separation in certain blends, while elastic modulus, fracture toughness and creep showed little dependence upon composition.
Saving ears and kidneys from cisplatin. (2013)

Cisplatin is a potent cytostatic drug, whose use is limited by its severe acute and chronic nephro-, oto-, and also peripheral neuro-toxicity. Since transporters are important mediators of specific cellular uptake of many drugs such as cisplatin, their role as possible targets of specific organ protection against undesired cisplatin toxicities is under investigation. Several transporters are able to mediate the movement of cisplatin across the plasma membranes: Copper transporter-1 (Ctr1), copper transporter-2 (Ctr2), P-type copper-transporting ATPases ATP7A and ATP7B, organic cation transporter-2 (OCT2), and multidrug extrusion transporter-1 (MATE1). Some of these transporters are also able to accept other platinum derivatives as substrates. In the present review article, we focus on the role of Ctr1 and OCT2 for cellular uptake of cisplatin and on the possibilities to reduce cisplatin-associated toxicities decreasing cisplatin uptake mediated by these transporters. The ubiquitously expressed Ctr1 seems to be involved in general cisplatin uptake in tumor and normal cells. Conversely, OCT2 expression is restricted to few cells such as renal, cochlear, and nervous cells, while its expression in some tumors seems to be epigenetically down-regulated. For this reason, specific inhibition of OCT2 may be effective in decreasing cisplatin uptake in non-target cells, without compromising its anti-tumoral efficacy, and therefore OCT2 may be the target for a suitable protective therapy.
The interfacial drag and the height of the wall layer in annular flows (1976)

Abstract A method to predict the height of the wall layer and the interfacial drag in annular flow under conditions that the flow rate of the entrained liquid is known is developed from measurements on air‐water flow in circular tubes. Flow conditions are found to be characterized by a generalized Martinelli flow parameter.
Flow Characteristics of Organopolysiloxane Fluids and Greases (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFlow Characteristics of Organopolysiloxane Fluids and GreasesC. C. Currie and B. F. SmithCite this: Ind. Eng. Chem. 1950, 42, 12, 2457–2462Publication Date (Print):December 1, 1950Publication History Published online1 May 2002Published inissue 1 December 1950https://pubs.acs.org/doi/10.1021/ie50492a023https://doi.org/10.1021/ie50492a023research-articleACS PublicationsRequest reuse permissionsArticle Views114Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
<title>Automated video summarization using speech transcripts</title> (2001)

Compact representations of video data can enable efficient video browsing. Such representations provide the user with information about the content of the particular sequence being examined while preserving the essential message. We propose a method to automatically generate video summaries for long videos. Our video summarization approach involves mainly two tasks: first, segmenting the video into small, coherent segments and second, ranking the resulting segments. Our proposed algorithm scores segments based on word frequency analysis of speech transcripts. Then a summary is generated by selecting the segments with the highest score to duration ratios and these are concatenating them. We have designed and performed a user study to evaluate the quality of summaries generated. Comparisons are made using our proposed algorithm and a random segment selection scheme based on statistical analysis of the user study results. Finally we discuss various issues that arise in evaluation of automatically generated video summaries.
Polymer–metal–organic framework core–shell framework nanofibers via electrospinning and their gas adsorption activities (2016)

In this study, we have fabricated of PAN@ZIF-8 core–shell nanofibers by combining electrospinning techniques and the MOF synthesis method.
Disruption of Bax Protein Prevents Neuronal Cell Death but Produces Cognitive Impairment in Mice following Traumatic Brain Injury (2008)

Apoptosis contributes to delayed neuronal cell death in traumatic brain injury (TBI). To investigate if Bax plays a role in neuronal cell death and functional outcome after TBI, Bax gene disrupted (null) mice and wild-type (WT) controls were subjected to the controlled cortical impact (CCI) model of TBI. Motor function in WT and Bax null mice was evaluated using the round beam balance and the wire grip test on days 0-5. Spatial memory was assessed using a Morris Water Maze adopted for mice on days 14-18 post-injury. For histopathological analysis, animals were sacrificed 24 h and 21 days post-injury. In all three behavioral tests, the sham and TBI-injured Bax null mice performed significantly worse than their WT sham and TBI-injured counterparts. However, Bax null mice exhibited a higher percentage of surviving neurons in the CA1 and CA3 regions of hippocampus measured at 21 days post-injury. At 24 h after trauma, Bax null mice had fewer TUNEL positive cells in the CA1 and dentate regions of hippocampus as compared to WT mice, suggesting that deletion of the Bax gene ameliorates hippocampal cell death after TBI. Sham-operated Bax null mice had significantly greater brain volume as compared to WT mice. Thus, it is possible that Bax deficiency in the transgenic mice produces developmental behavioral effects, perhaps due to Bax's role in regulating cell death during development.
An efficient, catalyst- and solvent-free<i>N</i>-formylation of aromatic and aliphatic amines (2011)

Abstract A simple, efficient, and cost-effective procedure for the synthesis of formamides under catalyst- and solvent-free conditions at 60°C using formic acid/ethyl formate as a formylating agent has been developed. The protocol is applicable to a wide variety of aromatic and aliphatic amines providing moderate to excellent yield of desired products.
ChemInform Abstract: C(3)‐Alkoxycephems. (1986)

Abstract Die Mitsunobu‐Reaktion der C(3)‐Hydroxycepheme (I) liefert vorwiegend die 3‐Alkoxy‐Derivate (III) neben geringen Mengen der C(4)‐alkylierten Verbindungen (IV).
SEROSA: SERvice oriented security architecture for Vehicular Communications (2013)

Modern vehicles are no longer mere mechanical devices; they comprise dozens of digital computing platforms, coordinated by an in-vehicle network, and have the potential to significantly enhance the digital life of individuals on the road. While this transformation has driven major advancements in road safety and transportation efficiency, significant work remains to be done to support the security and privacy requirements of the envisioned ecosystem of commercial services and applications (i.e., Internet access, video streaming, etc.). In the era when “service is everything and everything is a service”, Vehicular Communication (VC) systems cannot escape from this ongoing trend towards multi-service environments accessible from anywhere. To meet the diverse requirements of vehicle operators and Service Providers (SPs), we present SEROSA, a service-oriented security and privacy-preserving architecture for VC. By synthesizing existing VC standards and Web Services (WS), our architecture provides comprehensive identity and service management while ensuring interoperability with existing SPs. We fully implement our system and extensively assess its efficiency, practicality, and dependability. Overall, SEROSA significantly extends the state of the art and serves as a catalyst for the integration of vehicles into the vast domain of Internet-based services.
Direct Observation of Lattice Arrangement in MBE Grown GaAs–AlGaAs Superlattices (1983)

Observation is made of a cross section including the growth direction of an MBE grown GaAs–Al 0.28 Ga 0.72 As superlattice structure by a transmission electron microscope with a resolution of 1.4 Å. Relevant atoms are observed to be regularly aligned even across the heterointerface. There is no alloy clustering observed in the ternary alloy layer. Dislocation is clearly observed as a local disorder in lattice alignment for the first time in the MBE grown layer.
A holistic approach to service survivability (2003)

We present SABER (Survivability Architecture: Block, Evade, React), a proposed survivability architecture that blocks, evades and reacts to a variety of attacks by using several security and survivability mechanisms in an automated and coordinated fashion. Contrary to the ad hoc manner in which contemporary survivable systems are built-using isolated, independent security mechanisms such as firewalls, intrusion detection systems and software sandboxes-SABER integrates several different technologies in an attempt to provide a unified framework for responding to the wide range of attacks malicious insiders and outsiders can launch.
Low Ohmic Contact Resistance<i>m</i>-Plane AlGaN/GaN Heterojunction Field-Effect Transistors with Enhancement-Mode Operations (2010)

Low ohmic contact resistance m-plane AlGaN/GaN heterojunction field-effect transistors were demonstrated using a regrown n+-GaN contact layer. An ohmic contact resistance of 0.25 Ω·mm was obtained with an 80-nm-thick Si-doped regrown GaN contact layer deposited by metal organic chemical vapor deposition. Enhancement-mode m-plane AlGaN/GaN heterojunction field-effect transistors were demonstrated with a threshold voltage of +1.4 V and 2.0 mΩ·cm2 on-state resistances at +5 V of gate–source voltage.