gebhart/patrepeval huggingface dataset:
A Single-Step Colony-Forming Unit Assay for Unseparated Mobilized Peripheral Blood, Cord Blood, and Bone Marrow (2001)

The colony-forming unit (CFU) assay is exposed to a lot of variation, part of which is introduced by several enrichment strategies that are routinely performed before assessment of clonogenic capacity in mobilized peripheral blood (PB), bone marrow (BM), or cord blood (CB). We investigated the possibility to perform a single-step CFU assay by direct plating of PB, BM, or CB into CFU culture medium to obtain more reproducible results than after a standard Ficoll or lysis procedure. Direct plating implies the presence of red blood cells (RBC), white blood cells (WBC), and plasma in the CFU assay, which could possibly influence the outcome of the assay. Of all components, only the RBC was found to negatively influence CFU-GM growth if a concentration of > 0.02 x 10(9)/ml was present in the CFU culture medium. Subsequently, depending on the RBC concentration PB, BM, and CB samples were prediluted in triplicate or quadruplicate and plated into CFU medium. Lysis and/or Ficoll procedures were also performed in triplicate or quadruplicate on the same samples, and the mean colony number and coefficient of variation (CV) of the three techniques were compared. Significantly smaller CV values were found using the direct plating technique (all assays, mean 7.5%, range 1.6-15.6%) than after Ficoll separation (mean 18.0%, range 2.2-62.5%). Intermediate results were obtained with the lysis method (mean CV 11.6%, range 3.3-29%). In most samples, and especially in those with a very low number of clonogenic cells per milliliter, more colonies were detected with the direct plating method than with either the lysis or Ficoll method. In conclusion, the single-step direct plating method significantly enhances reproducibility of the CFU assay for PB, BM, and CB samples in comparison with standard techniques by circumvention of loss of colony formation and by decreasing variability. Furthermore, the direct plating technique is a timesaving assay.
The design of distance-learning service creation environment (2002)

Based on the object-oriented perspective and the reuse-driven feature of algorithmic modules, a distance-learning service creation environment has been deployed. The conceptual model of the environment consists of four planes: the learning service feature plane, the global functional plane, the distributed functional plane and the physical plane. The first plane represents a service-oriented view to describe the learning service-related behaviour, the second plane represents a service-independent view realized by the learning service building block, the third plane represents a distributed model of the service network, and the last plane represents a physical model of the service network. The environment is a powerful tool that allows users to quickly create and customize distance-learning services under broadband networks without having to know all the detailed knowledge of the network infrastructure.
Mapping the Human Connectome (2012)

Knowledge of the properties of white matter fiber tracts isa crucial and necessary step toward a precise understanding of the functional architecture of the living human brain. Previously, this knowledge was severely limited, as it was difficult to visualize these structures or measure their functions in vivo. The HCP has recently generated considerable interest because of its potential to explore connectivity and its relationship with genetics and behavior. For neuroscientists and the lay public alike, the ability to assess, measure, and explore this wealth of layered information concerning how the brain is wired is a much sought after prize.The navigation of the human connectome and the discovery of how it is affected through genetics, and in a range of neurological and psychiatric diseases, have far reaching implications. From a range of ongoing connectomics related activities, the systematic characterization of brain connectedness and the resulting functional aspects of such connectivity will not only realize the work of Ramón y Cajal and others, but will also greatly expand our understanding of the brain, the mind, and what it is to be truly human. The similarities and differences that mark normal diversity will help us to understand variation among people and set the stage to chart genetic influences on typical brain development and decline during aging. What is more, an understanding of how brains might become disordered will shed light on autism, schizophrenia, Alzheimer’s, and other diseases that exact a tremendous and terrible social and economic toll.
Effect of sitosterol on autoxidation rate and product composition in a model lipid system (1984)

Abstract The effect of 5% sitosterol on the autoxidation of tristearin at 120°C was investigated. It was found that sitosterol caused a two‐fold increase in the process rate; this effect was unchanged at peroxide concentrations of up to 350 mEq kg −‐1 . It was established that introduction of 5% sitosterol considerably increased the concentration of oxidised products in tristearin (from 0.5 to 6.5%) after oxidation at 120°C for 7h. The degree of oxidation of sitosterol in the system was found to be 56%. The structure and composition of oxidised products in the two lipid systems (tristearin, and tristearin+5% sitosterol) were determined. Conclusions were drawn concerning the effect of the lipid medium on the composition and structure of the products of sitosterol autoxidation.
The ratio of arginine to dimethylarginines is reduced and predicts outcomes in patients with severe sepsis* (2011)

The arginine-to-dimethylarginine ratio is associated with severe sepsis, severity of illness, and clinical outcomes. The arginine-to-dimethylarginine ratio may be a useful biomarker, and interventions designed to augment systemic arginine availability in severe sepsis may still be worthy of investigation.
Ethiopia as a presumed wintering area for the eastern grasshopper warbler Locustella naevia straminea (1978)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Genetic algorithm and gravitational emulation based hybrid load balancing strategy in cloud computing (2015)

Cloud computing enables a new supplement of consumption and delivery model for internet based services and protocol. It helps to provide software, hardware and data in form of collaborative services on the demand of the end user. To meet the QoS and ensure high interoperability and scalability is one of the most challenging tasks for cloud service provider. However, there are also several technical challenges that need to be tackled before the benefits can be fully realized. Among them reliability, resource provisioning, and efficient resources consuming etc are major concern. Load balancing also one of them. It includes selecting a proper node that must be full filled end user demand and also distribution of dynamic workload evenly into the multiple nodes. So load balancing can be described as an optimization problem and should be adapting nature due to the changing needs. In this paper we suggest a novel load balancing strategy to search under loaded node to balance load from overwhelmed node. CloudAnalyst used as a simulation tool for the proposed load balancing strategy. Experimental results of the sample application are really very encouraging. Significantly the results of the proposed algorithm are compared and outperformed the traditional strategy like First Come First Serve(FCFS), local search algorithm like Stochastic Hill Climbing(SHC) and soft computing approaches like Genetic Algorithm (GA) and Ant Colony Optimization(ACO).
Coloring Schemes and the Dynamical Structure of Iterated Function Systems (1990)

The IFS method holds great potential for image compression, and can aid students in understanding fractal aspects of objects he method of Iterated Function Systems (lFS) generates images, often fractal, in the plane by applying a sequence of contraction mappings to points in the plane.A point in the image can be given an address by the sequence of fUnctions applied to specify smaller and smaller neighborhoods of the point.We describe a way in which this addressing scheme can be used to assign colors to the image.Our method appears to be complementary to Barnsley's coloring procedure, and has pedagogical applications for elucidating Barnsley's Collage Theorem. Iterated Function SystemsIterated Function Systems have attracted considerable interest as a simple method for generating complicated Michael Frame is an Associate Professor of Mathematics at Union College.He teaches two courses in fractals and chaos.In addition to writing a text on fractals.he is attempting to use fractals to approach problems in topology.Lynne Erdman graduated from Union College with a degree in mathematics.She currently works for Nike in Portland.Oregon.
Scalable and Interactive Visual Analysis of Financial Wire Transactions for Fraud Detection (2008)

Large financial institutions such as Bank of America handle hundreds of thousands of wire transactions per day. Although most transactions are legitimate, these institutions have legal and financial obligations to discover those that are suspicious. With the methods of fraudulent activities ever changing, searching on predefined patterns is often insufficient in detecting previously undiscovered methods. In this paper, we present a set of coordinated visualizations based on identifying specific keywords within the wire transactions. The different views used in our system depict relationships among keywords and accounts over time. Furthermore, we introduce a search-by-example technique, which extracts accounts that show similar transaction patterns. Our system can be connected to a database to handle millions of transactions and still preserve high interactivity. In collaboration with the Anti-Money Laundering division at Bank of America, we demonstrate that using our tool, investigators are able to detect accounts and transactions that exhibit suspicious behaviors.
Parental Age at Child's Birth and Son's Risk of Prostate Cancer: The Framingham Study (1999)

The authors examined the relation of parental age at birth to the risk of prostate cancer among sons with the use of data from the Framingham Study. During 42 years of follow-up (1949-1993), 141 prostate cancer cases occurred in 2,164 men. All but six cases were confirmed by histologic report. The incidence rate of prostate cancer increased from 1.70 per 1,000 person-years among sons in the lowest quartile of paternal age (<27 years), to 2.00, 2.32, and 2.74 among those of each increased paternal age category (27-<32, 32-<38, and > or =38 years), respectively. After adjustment for age and other covariates, men in the second, third, and oldest quartiles of paternal age had 1.2, 1.3, and 1.7 times increased risk of prostate cancer compared with men in the youngest quartile (p for trend = 0.049). Further adjustment for maternal age did not change the relation materially. The association of older paternal age with risk of early-onset prostate cancer (<65 years) appeared stronger than that with late-onset disease (265 years). No increased risk of prostate cancer was observed among subjects in the older maternal age category. The effect of increased paternal age on prostate cancer risk may operate through increased germ cell mutation rate or by mechanisms not yet defined.
An electron spin polarization study of the interaction of photoexcited triplet molecules with mono- and polynitroxyl stable free radicals (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAn electron spin polarization study of the interaction of photoexcited triplet molecules with mono- and polynitroxyl stable free radicalsNicholas J. Turro, Igor V. Khudyakov, Stefan H. Bossmann, and David W. DwyerCite this: J. Phys. Chem. 1993, 97, 6, 1138–1146Publication Date (Print):February 1, 1993Publication History Published online1 May 2002Published inissue 1 February 1993https://pubs.acs.org/doi/10.1021/j100108a007https://doi.org/10.1021/j100108a007research-articleACS PublicationsRequest reuse permissionsArticle Views285Altmetric-Citations46LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Approche croisée des aspects culturels des révolutions modernes dans le monde atlantique (2010)

notamment par photocopie, n'est autorise que dans les limites des conditions gnrales d'utilisation du site ou, le cas chant, des conditions gnrales de la licence souscrite par votre tablissement. Toute autre reproduction ou reprsentation, en tout ou partie, sous quelque forme et de quelque manire que ce soit, est interdite sauf accord pralable et crit de l'diteur, en dehors des cas prvus par la lgislation en vigueur en France. Il est prcis que son stockage dans une base de donnes est galement interdit.
First successful culture of the marine dinoflagellate Dinophysis acuminata (2006)

The dinoflagellate genus Dinophysis includes several species that cause diarrhetic shellfish poisoning, none of which have yet been established in culture. We report on the maintenance of Dinophysis acuminata cultures that were established in December 2005 and also on its feeding mechanism, and growth rates when fed the ciliate prey Myrionecta rubra with and without the addition of the cryptophyte Teleaulax sp. D. acuminata grew well (growth rate of 0.95 d -1 ) in laboratory culture when supplied with the marine ciliate M. rubra as prey, reaching a maximum concentration of about 2400 cells ml -1 at the end of the feeding experiment. In contrast, D. acuminata did not show sustained growth in the absence of the ciliate or when provided the cryptophyte Teleaulax sp. as prey (D. acuminata used its peduncle to extract the cell contents of the prey organism, M. rubra). Based on the prey-predator interactions occurring among D. acuminata, M. rubra, and Teleaulax sp. in this study, establishment of permanent culture of the dinoflagellate D. acuminata may facilitate a better understanding of the ecophysiology, biology, and toxicology of Dinophysis species, as well as the evolution of dinoflagellate plastids.
Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodies (1999)

Circulating immune complexes (CICs) isolated from sera of patients with IgA nephropathy (IgAN) consist of undergalactosylated, mostly polymeric, and J chain-containing IgA1 and IgG antibodies specific for N-acetylgalactosamine (GalNAc) residues in O-linked glycans of the hinge region of IgA1 heavy chains. Antibodies with such specificity occur in sera of IgAN patients, and in smaller quantities in patients with non-IgA proliferative glomerulonephritis and in healthy controls; they are present mainly in the IgG (predominantly IgG2 subclass), and less frequently in the IgA1 isotype. Their specificity for GalNAc was determined by reactivity with IgA1 myeloma proteins with enzymatically removed N-acetylneuraminic acid (NeuNAc) and galactose (Gal); removal of the O-linked glycans of IgA1 resulted in significantly decreased reactivity. Furthermore, IgA2 proteins that lack the hinge region with O-linked glycans but are otherwise structurally similar to IgA1 did not react with IgG or IgA1 antibodies. The re-formation of isolated and acid-dissociated CICs was inhibited more effectively by IgA1 lacking NeuNAc and Gal than by intact IgA1. Immobilized GalNAc and asialo-ovine submaxillary mucin (rich in O-linked glycans) were also effective inhibitors. Our results suggest that the deficiency of Gal in the hinge region of IgA1 molecules results in the generation of antigenic determinants containing GalNAc residues that are recognized by naturally occurring IgG and IgA1 antibodies.
Integration of a low permittivity spin-on embedded hardmask for Cu/SiLK resin dual damascene (2001)

The feasibility of integrating a low permittivity spin-on hardmask (SoHM) into a Cu dual damascene structure using SiLK* Semiconductor Resin (*trademark of The Dow Chemical Company) has been investigated. The study focussed on the replacement of the embedded etch stop deposited by chemical vapor deposition (CVD) by a low permittivity inorganic film deposited by traditional spin coating. The evaluation was performed using an existing damascene test vehicle. The etch selectivity was evaluated by applying different SoHM thicknesses and etch times. The patterning chemistry used was O/sub 2//N/sub 2/ based, in a high density TCP etch tool. The electrical data collected indicated no significant yield difference when using an embedded SoHM. The integrated k value of the SoHM film is 3.2, as compared to /spl sim/4.0 for SiO/sub 2/ films.
Radiofrequency Ablation of Spinal Tumors (2000)

Radiofrequency Ablation of Spinal TumorsTemperature Distribution in the Spinal CanalDamian E. Dupuy1, Raymond Hong1, Brian Oliver2 and S. Nahum Goldberg2Audio Available | Share
Utilization of oxidative pressure for enhanced production of poly-beta-hydroxybutyrate and poly(3-hydroxybutyrate-3-hydroxyvalerate) in Ralstonia eutropha. (2000)

Ralstonia eutropha was cultivated under oxidative conditions in the presence of hydrogen peroxide and methyl viologen to stimulate the flux of NADPH to the PHA biosynthesis pathway. The effects of oxidants on the biosynthesis of poly-beta-hydroxybutyrate(PHB) and poly(3-hydroxybutyrate-3-hydroxyvalerate)[P(3HB-3HV)] were investigated. The biosynthesis rate and concentrations of PHB and its copolymer P(3HB-3HV) increased significantly under the oxidative pressure of methyl viologen, meanwhile, the molar fraction of 3HV in P(3HB-3HV) remained constant. The effect of methyl viologen on the flux of the intermediate compounds was investigated by measuring the activity of enzymes related to PHB biosynthesis, glucose 6-phosphate dehydrogenase (G6PD), and NADPH level. The oxidant significantly activated the G6PD of R. eutropha, increasing the NADPH level used for the reduction reaction of acetoacetyl-CoA to beta-hydroxybutyryl-CoA, thereby enhancing the biosynthesis of PHB and P(3HB-3HV).
A Novel Approach for Cooling Electronics Using a Combined Heat Pipe andThermoelectric Module (2009)

The development of effective cooling systems for microprocessors, specifically for CPU and other computer chips, is greatly important due to growth of high speed performance chips, which operate at elevated heat rates. The same issues apply for adjacent units including RAM and HDD also contributing to overall generation of heat inside computer. Problem statement: Conventional cooling system for desktop PC has many problems, especially cooling performance. Lifespan of devices and reliable operation are largely dependent on junction temperature. Total power dissipation of recently introduced, new generation microprocessors had been increasing rapidly, pushing desktop system cooling technology close to its limits. Approach: Present research focused on a system for removal of dissipated heat that combined the advantages of heat pipe and thermoelectric modules. Proposed research presented a numerical analysis of a novel cooling system for electronics. Configuration studied concerns microprocessors and other computer ships. Simulations performed in this research were based on use of computational fluid dynamics and results obtained in terms of cooling efficiencies were compared to those of the traditional cooling. Heat resistance and temperature of each component were investigated in this modeling. Results: Lowest core temperature was found below 75°C and total thermal resistance of cooling system is 0.095°C/W. Conclusion/Recommendations: Proposed cooling systems had sufficient capacity for cooling 200 W heat dissipation. Temperature of proposed cooling system is lower than both existing cooling systems. Temperature of all components, CPU, heat pipe, TEC and heat sink were below 75°C. Thermal resistance characteristic of a cooling system had a major effect on cooling performance.
On the Determination of Ostwald Ripening Rates from Dynamic Light Scattering Measurements (1999)

The Ostwald ripening rate of several alkane in water emulsions stabilized by a nonionic surfactant is determined from dynamic light scattering (DLS) measurements. With the aid of computer simulations, the intensity weighted droplet radii obtained with DLS are converted to number averages, by taking the form of the droplet size distributionwhich evolves continuously toward a stationary distributioninto account. Thereby the effect of the transition from an initial, log-normal size distribution toward its stationary form is included. Second a model is proposed to account for the effect of the finite size of the surfactant layer (surrounding each oil droplet) on the measured particle size and thus on the ripening rate. It is found that both the effect of the transition from a nonstationary regime toward the stationary Lifshitz−Slyozov−Wagner regime and the effect of the finite size of the surfactant layer influence the ripening rates significantly.
Load flow analysis of radial distribution network using linear data structure (2014)

Distribution systems hold a very significant position in the power system since it is the main point of link between bulk power and consumers. A planned and effective distribution network is the key to cope up with the ever increasing demand for domestic, industrial and commercial load. The load-flow study of radial distribution network is of prime importance for effective planning of load transfers. Power companies are interested in finding the most efficient configuration for minimization of real power loses and load balancing among distribution feeders to save energy and enhance the over all performance of distribution system. This thesis presents a fast and efficient method for load-flow analysis of radial distribution networks. The proposed method is based on linear data structure. The order of time and space complexity is reported here. There is significant saving in no. of steps execution. Using graph theory concept and exploiting multi-cores architecture, the proposed method for load flow can be further investigated for obtaining more optimized solutions.
Metalloproteinase-9 deficiency protects against hepatic ischemia/reperfusion injury (2007)

These results support critical functions for MMP-9 in leukocyte recruitment and activation leading to liver damage. Moreover, they provide the rationale for identifying inhibitors to specifically target MMP-9 in vivo as a potential therapeutic approach in liver I/R injury.