WEIL'S DISEASE; REPORT OF THREE CASES, INCLUDING THE MORBID ANATOMY OF ONE CASE, AND A BRIEF REVIEW OF THE PERTINENT LITERATURE (1941)

Article1 August 1941WEIL'S DISEASE; REPORT OF THREE CASES, INCLUDING THE MORBID ANATOMY OF ONE CASE, AND A BRIEF REVIEW OF THE PERTINENT LITERATUREJOEL J. WHITE, M.D., F.A.C.P., JOHN V. PREVOST, M.D.JOEL J. WHITE, M.D., F.A.C.P.Search for more papers by this author, JOHN V. PREVOST, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-15-2-207 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1886, H. A. Weil1described a syndrome characterized by the sudden onset of prostration, fever, myalgia, jaundice, hemorrhagic tendencies and renal damage which, today, is known by his name. Inada and Ido2discovered the spirochete in the liver of a guinea pig, inoculated with the blood of a patient suffering from the disease in 1915, and believed it to be the causative agent. They succeeded in isolating and culturing the organism and named itSpirocheta icterohemorrhagica. The following year Inada3and a group of Japanese reported extensively on the etiology and mode of infection of this disease. In 1918,...Bibliography1. WEIL HA: Über eine eigenthümliche mit Milztumor, Icterus und Nephritis einhergehende, acute Infectionskrankheit, Deutsch. Arch. f. klin. Med., 1886, xxxix, 209-232. Google Scholar2. INADAIDO RY: Tokyo Ijishinshi, 1915, No. 1908, quoted by Inada et al.3 Google Scholar3. INADAIDOHOKIKANEKOITO RYRRH: The etiology, mode of infection and specific therapy of Weil's disease (spirochetosis icterohemorrhagica), Jr. Exper. Med., 1916, xxiii, 377. CrossrefGoogle Scholar4. NOGUCHI H: Morphological characteristics and nomenclature of Leptospira (Spirocheta) icterohemorrhagica, Jr. Exper. Med., 1918, xxvii, 575. CrossrefGoogle Scholar5. 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FRUGONICAPPELLANI CS: Intorno all' eziologia dell' ittero epidemico, Riforma med., Napoli, 1917, xxxiii, 439, quoted by Jeghers, et al.15 Google Scholar34. SNELL AM: Personal communication, Mayo Clinic, Rochester, Minnesota, November, 1939. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication January 31, 1940.From the Medical Service of U. S. Naval Hospital, Philadelphia, Pa. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byWeil's disease 1 August 1941Volume 15, Issue 2Page: 207-225KeywordsBloodEtiologyFeversGuinea pigsInfectious diseasesLiverLiver diseasesMedical servicesMyalgiaSpirochetes ePublished: 1 December 2008 Issue Published: 1 August 1941 PDF downloadLoading ...