gebhart/patrepeval huggingface dataset:
Effect of Direct-Fed Fibrolytic Enzymes on the Lactational Performance of Dairy Cows (1999)

In trial 1, 30 midlactation (213 d in milk) Holstein cows were randomly assigned to a control or enzyme treatment in a two-period crossover design and were fed a total mixed ration based on alfalfa hay and silage. Cows on the enzyme treatment received an enzyme solution containing cellulases and xylanases, which was sprayed on the forage component of the ration at a rate of 1.65 ml/kg of forage dry matter (DM) between 8 and 24 h prior to feeding. Cows consuming the forage treated with enzyme produced more milk (27.2 vs. 25.9 kg/d) and digested more DM per day than did cows fed the control forage. In trial 2, 40 early lactation Holstein cows were assigned to one of four treatments for 16 wk. Following a 2-wk covariate period, cows were assigned to 1) no enzyme treatment, 2) a low (1.25 ml/kg of forage DM) enzyme treatment, 3) a medium (2.5 ml/kg of forage DM) enzyme treatment, or 4) a high (5.0 ml/kg of forage DM) enzyme treatment. Enzymes were a 2:1 combination of cellulase and xylanase diluted in water and sprayed on a combination of alfalfa hay and silage and whole cottonseed immediately before mixing with a concentrate based on barley. Dry matter intakes were similar for cows on treatments 2, 3, and 4 and were greater than those for cows on treatment 1. Production of milk, 3.5% fat-corrected milk, and energy-corrected milk was greater for cows on treatment 3 than for cows on treatment 1. Fibrolytic enzymes applied to the forage portion of the rations prior to feeding improved lactational performance of early and midlactation cows.
Chemical Composition, Antibacterial Properties and Mechanism of Action of Essential Oil from Clove Buds against Staphylococcus aureus (2016)

The essential oil of clove has a wide range of pharmacological and biological activities and is widely used in the medicine, fragrance and flavoring industries. In this work, 22 components of the essential oil obtained from clove buds were identified. Eugenol was the major component (76.23%). The essential oil exhibited strong antibacterial activity against Staphylococcus aureus ATCC 25923 with a minimum inhibitory concentration (MIC) of 0.625 mg/mL, and the antibacterial effects depended on its concentration and action time. Kill-time assays also confirmed the essential oil had a significant effect on the growth rate of surviving S. aureus. We hypothesized that the essential oil may interact with the cell wall and membrane first. On the one hand it destroys cell wall and membranes, next causing the losses of vital intracellular materials, which finally result in the bacterial death. Besides, essential oil penetrates to the cytoplasmic membrane or enters inside the cell after destruction of cell structure, and then inhibits the normal synthesis of DNA and proteins that are required for bacterial growth. These results suggested that the effects of the clove essential oil on the growth inhibition of S. aureus may be at the molecular level rather than only physical damage.
A chemotaxonomic analysis of cannabinoid variation in <i>Cannabis</i> (Cannabaceae) (2004)

Cannabinoids are important chemotaxonomic markers unique to Cannabis. Previous studies show that a plant's dry-weight ratio of Δ(9)-tetrahydrocannabinol (THC) to cannabidiol (CBD) can be assigned to one of three chemotypes and that alleles B(D) and B(T) encode alloenzymes that catalyze the conversion of cannabigerol to CBD and THC, respectively. In the present study, the frequencies of B(D) and B(T) in sample populations of 157 Cannabis accessions were determined from CBD and THC banding patterns, visualized by starch gel electrophoresis. Gas chromatography was used to quantify cannabinoid levels in 96 of the same accessions. The data were interpreted with respect to previous analyses of genetic and morphological variation in the same germplasm collection. Two biotypes (infraspecific taxa of unassigned rank) of C. sativa and four biotypes of C. indica were recognized. Mean THC levels and the frequency of B(T) were significantly higher in C. indica than C. sativa. The proportion of high THC/CBD chemotype plants in most accessions assigned to C. sativa was <25% and in most accessions assigned to C. indica was >25%. Plants with relatively high levels of tetrahydrocannabivarin (THCV) and/or cannabidivarin (CBDV) were common only in C. indica. This study supports a two-species concept of Cannabis.
Oxidative metabolism of polymorphonuclear leukocytes (PMN) in patients with IgA nephropathy (1992)

The production of hydrogen peroxide (H2O2) by neutrophilic polymorphonuclear leukocytes (PMN) after stimulation and the infiltration of PMN in glomeruli were determined in 20 patients with primary IgA nephropathy. The H2O2 production of PMN after the stimulation was measured with a spectrophotometer using horseradish peroxidase as substrate. The results were as follows: 1) when PMN were pretreated with cytochalasin B, H2O2 production after stimulation with heat-aggregated IgG (IgG) or serum-treated zymosan (STZ) was significantly higher in patients with IgA nephropathy than in controls, and 2) there was an increased amount of PMN localized in glomeruli in patients with IgA nephropathy using immunofluorescence of monoclonal anti-PMN antibody. It appeared that the increased renal infiltration of PMN which have a high potential for production of reactive oxygen species might induce the glomerular injuries in patients with IgA nephropathy.
Estimating Risk of Cancer Associated With Radiation Exposure From 64-Slice Computed Tomography Coronary Angiography (2007)

These estimates derived from our simulation models suggest that use of 64-slice CTCA is associated with a nonnegligible LAR of cancer. This risk varies markedly and is considerably greater for women, younger patients, and for combined cardiac and aortic scans.
Teaching the New Inequalities: Using the<i>Human Development Report</i>as Class Text (2002)

In this article we share our experiences helping students to think critically about global issues by using the data and the conceptual innovations presented by the authors of the United Nations Development Programme’s Human Development Report We discuss a number of strategies we have applied to actively engage students in the analysis of the extensive data in the Report and the approaches we have taken to help our students understand both the research and the policy implications of the diverse conceptual frameworks introduced in each annual edition. By using a publication that introduces new concepts, new measures, and new insights in each annual edition, we help our students to see how social scientists work and how knowledge is constructed. At the same time, by requiring them to use the data to analyze, compare, and conceptualize, we show them they can “do” social science and discover for themselves some of the realities of the global community described in the more traditional texts.
Naturally occurring K vitamins inhibit pancreatic cancer cell survival through a caspase‐dependent pathway (2009)

These data show that naturally-occurring, non-toxic K vitamins can inhibit the survival of some pancreatic cancer cell lines. These novel, safe and clinically-utilized agents initiate a caspase-dependent apoptosis via the MAP kinase pathway and could potentially benefit patients with pancreatic cancer either as a single agent or in combination with chemotherapy for treatment, or for prevention of recurrence of pancreas cancer post resection.
Point and Counterpoint: Computers in the Classrooms (1986)

The writer poses some of the more common objections to the introduction of computers into the curriculum, and provides a response to each.
Health-related quality of life in functional GI disorders: focus on constipation and resource utilization (2002)

Constipation is common in the Canadian population and significantly impairs health-related quality of life. Poor quality of life is an important predictor of health care utilization in these subjects.
Optimizing the efficacy of Paecilomyces lilacinus (strain 251) for the control of root-knot nematodes. (2004)

The egg pathogenic fungus Paecilomyces lilacinus (strain 251) is a biocontrol fungus with a potential range of activity to control the worldwide most important plant parasitic nematodes. This biological nematicide may be an useful tool in an integrated approach to control mainly sedentary nematodes. Greenhouse experiments were conducted with the root-knot nematodes Meloidogyne incognita and M. hapla on tomato. P. lilacinus, formulated as WG (BIOACT WG), was incorporated into soil inoculated with root-knot nematode eggs prior to transplanting the susceptible tomato cultivar "Hellfrucht". Furthermore, soil treatments were combined with seedling treatments 24 hours before transplanting and a soil drench 2 weeks after planting, respectively. Seedling and post planting treatment was also combined with a soil treatment at planting. All single or combination treatments tested decreased the gall index and the number of egg masses compared to the untreated control 12 weeks after planting. However, the combination of the seedling treatment with a pre- or at-planting application of P. lilacinus was necessary to achieve higher levels of control. Additional post plant drenching resulted in only a slight increase In efficacy. To the feasibility of this modified application system for the control of root-knot nematodes, a yield experiment was conducted with M. hapla and the susceptible cultivar "Gnom F1 Hybrid". It could be demonstrated that the above mentioned combination of pre-planting application plus the seedling and one post plant drench gave the best control and resulted in a significant fruit yield increase in concurrence with a decrease in number of galls per root.
Unequal Opportunities: Women's Employment in England, 1800-1918 (1987)

`Unequal Opportunities is essential reading for historians of women's work and specialists in British and European social and labour history.' Susan D. Pennybacker, Trinity College at Hartford `This is a strong and extremely useful collection, which presents a marvellous opportunity for future works of synthesis. Anyone working on the social and economic history of the period 1800 - 1918 will ignore it at their peril.' Social History Society Newsletter '[An] excellent collection' Times Literary Supplement 'This collection..presents an admirably balanced view of women's paid work in urban England. The authors pose a series of interesting analytical questions and grapple creatively with vexed problems of methodology in the face of past neglect, sparse documentary evidence and biaised sources...a most useful collection..it is a safe bet that several of its essays will become standard texts in women's history and..in labour history courses.' Social History (1985) 216 x 138mm, 312 pages, illustrations #7.50 (paperback) 0-631-13956-7 #25.00 (hardback) 0-631-13955-9 (1986) 5 1/2 x 8 1/2, 312 pages, illustrations $14.95 (paper) 0-631-13956-7 $49.95 (cloth) 0-631-13955-9
Adsorption and Desorption of Stearic Acid Self-Assembled Monolayers on Aluminum Oxide (2007)

Development of coatings to minimize unwanted surface adsorption is extremely important for their use in applications, such as sensors and medical implants. Self-assembled monolayers (SAMs) are an excellent choice for coatings that minimize nonspecific adsorption because they can be uniform and have a very high surface coverage. Another equally important characteristic of such coatings is their stability. In the present study, both the bonding mechanism and the stability of stearic acid SAMs on two aluminum oxides (single-crystal C-plane aluminum oxide (sapphire) and amorphous aluminum oxide (alumina)) are investigated. The adsorption mechanism is investigated by ex situ X-ray photoelectron spectroscopy and infrared (IR) spectroscopy. The results revealed that stearic acid binds to sapphire surfaces via a bidentate interaction of carboxylate with two oxygen atoms while it binds to alumina surfaces via both bidentate and monodentate interactions. Desorption kinetics of stearic acid self-organized on both aluminum oxide surfaces into water is explored by ex situ tapping mode atomic force microscopy, IR spectroscopy, and contact angle measurements. The results exhibit that the SAMs of stearic acid formed on sapphire are not stable in water and are continuously lost through desorption. Water contact angle measurements of SAMs that are immersed in water further indicate that the desorption rate of adsorbates from atomically smooth terrace sites is substantially faster than that of adsorbates from the sites of surface defects due to weaker molecular interaction with the smooth surface. A time-dependent desorption profile of SAMs grown on amorphous alumina reveals that contact angles decrease monotonically without any regional distinction, providing further evidence for the presence of adsorption sites with different types of affinity on the amorphous alumina surface.
Indoor Air Quality Engineering (2004)

Indoor Air Quality Engineering covers a wide range of indoor air quality engineering principles and applications, providing guidelines for identifying and analyzing indoor air quality problems as well as designing a system to mitigate these problems. Structured into three sections - properties and behavior of airborne pollutants, measurement and sa
Rescue of Sendai virus cDNA templates with cDNA clones expressing parainfluenza virus type 3 N, P and L proteins (1996)

Several years ago, we reported that a Sendai virus (SeV) defective genome (DIH4UV) could be rescued in vivo with human parainfluenza virus type 1 (hPIV1) and bovine PIV3 but not by measles virus or vesicular stomatitis virus. It was concluded that the cis-acting RNA sequences were conserved within the SeV/PIV1/PIV3 group but that interactions between the polymerase complex (P-L) and the template protein N were unique for each virus. We have re-examined these conclusions using proteins expressed from cloned N, P and L genes for SeV and PIV3. The results demonstrate the specificity of the protein-protein interactions between polymerase and template, and confirm the prediction of the earlier work that PIV3 N, P and L proteins are capable of assembling and replicating SeV mini-genomes also expressed from a cDNA clone.
Tumor‐antigen‐specific humoral immune response of animals to anti‐idiotypic antibodies and comparative serological analysis of patients with small‐cell lung carcinoma (1992)

We have previously developed 3 monoclonal anti-idiotypic antibodies (Ab2) of LOU rat origin directed against the binding site of the murine monoclonal IgM LAM8, which recognizes the small-cell lung carcinoma (SCLC)-associated sialoglycoprotein antigen sGP 90-135. The aim of this study was to compare the efficiencies of these 3 Ab2, designated LY8-229, LX8-531 and LX8-632, to induce antigen-specific immunity in different animal species without prior exposure of the recipients to the nominal antigen, and thereby possibly select an Ab2 candidate for active immunotherapy against SCLC in patients. The feasibility of this approach was further evaluated by a serological analysis of patients with SCLC compared with healthy individuals, in whom the spontaneous antibody reactivities against SCLC cell lines and Ab2 were tested. LY8-229 was shown to be the most effective Ab2 in inducing antigen-specific antibodies in BALB/c mice, CBA/J/Zur mice and one NZW rabbit. Furthermore, LY8-229 was the only Ab2 against which significantly elevated idiotype-specific antibody reactivities existed in sera of patients with SCLC. These reactivities correlated positively with binding to antigen-positive tumor cells. Our findings suggest that LY8-229 represents in its reactivity pattern the nominal SCLC antigen in humans also, and therefore may be of diagnostic and possibly therapeutic relevance for patients with SCLC.
Quantification of line-edge roughness of photoresists. I. A comparison between off-line and on-line analysis of top-down scanning electron microscopy images (2003)

An off-line image analysis algorithm and software is developed for the calculation of line-edge roughness (LER) of resist lines, and is successfully compared with the on-line LER measurements. The effect of several image-processing parameters affecting the fidelity of the off-line LER measurement is examined. The parameters studied include the scanning electron microscopy magnification, the image pixel size dimension, the Gaussian noise-smoothing filter parameters, and the line-edge determination algorithm. The issues of adequate statistics and appropriate sampling frequency are also investigated. The advantages of off-line LER quantification and recommendations for the on-line measurement are discussed. Having introduced a robust algorithm for edge-detection in Paper I, Paper II [V. Constantoudis et al., J. Vac. Sci. Technol. B 21, 1019 (2003)] of this series introduces the appropriate parameters to fully quantify LER.
Functions of dystrophin and dystrophin associated proteins (1997)

Dystrophin is a protein product of the X-linked gene mutation that is responsible for Duchenne and Becker muscular dystrophies. The protein binds actin and associates with dystrophin-glycoprotein complex to link the cytoskeleton to the extracellular matrix. Defects in the components of the dystrophin-glycoprotein complex are responsible for several phenotypes of muscular dystrophy.
A Novel Approach for LTCC Packaging Using a PBG Structure for Shielding and Package Mode Suppression (2003)

A packaging solution for multifunctional modules up to an operating frequency of 50 GHz based on Low Temperature Cofired Ceramics (LTCC) is presented in this paper. A Ball Grid Array (BGA) as well as a Land Grid Array (LGA) transition from Printed Circuit Board (PCB) into a surface mounted module are proposed. They use a Photonic Bandgap (PBG) structure to suppress the excitation of parasitic modes e.g. by the SMT interconnect. This approach provides process tolerant transitions as well as it allows the integration of wave guide structures in buried layers. This measure provides a greater flexibility in the design of microwave circuits and a major potential for miniaturisation of microwave subsystems.
Construction and evaluation of multi-touch screens using multiple cameras located on the side of the display (2010)

We applied a computer vision based method and developed multi-touch technology to be adopted in various display types. In the selected design, multiple cameras are placed on the side of the display with their optical axis parallel to the screen. The display edges opposite the cameras are illuminated and fingers are detected since they block the light in the camera images. The approach is scalable and can be used in a wide variety of displays. Due to self-occlusion of the touchpoints, it is challenging to relate camera measurements to tracked points. In this paper, we present our approach for tracking and managing multiple touchpoints in such camera set-ups. We describe the mathematical background for modeling and calibrating the cameras, the design of the extended Kalman filter for point tracking, and the logic for adding, updating and removing the touchpoints. We analyze the potential accuracy and robustness of the system using several simulations and present two different real-life implementations of the approach.
The Immunophilin Ligands Cyclosporin A and FK506 Suppress Prostate Cancer Cell Growth by Androgen Receptor-Dependent and -Independent Mechanisms (2007)

The androgen receptor (AR) contributes to growth of prostate cancer even under conditions of androgen ablation. Thus, new strategies to target AR activity are needed. The AR interacts with the immunophilin FK506-binding protein 52 (FKBP52), and studies in the FKBP52 knockout mouse have shown that this protein is essential to AR activity in the prostate. Therefore, we tested whether the immunophilin ligand FK506 affected AR activity in prostate cancer cell lines. We also tested the hypothesis that the AR interacts with another immunophilin, cyclophilin 40 (Cyp40), and is regulated by its cognate ligand cyclosporin A (CsA). We show that levels of FKBP52, FKBP51, Cyp40, and a related co-chaperone PP5 were much higher in prostate cancer cells lines [(LNCaP), PC-3, and DU145] compared with primary prostate cells, and that the AR of LNCaP cells can interact with Cyp40. In the absence of androgen, CsA caused inhibition of cell growth in the AR-positive LNCaP and AR-negative PC-3 and DU145 cell lines. Interestingly, FK506 only inhibited LNCaP cells, suggesting a dependence on the AR for this effect. Both CsA and FK506 inhibited growth without inducing apoptosis. In LNCaP cells, CsA completely blocked androgen-stimulated growth, whereas FK506 was partially effective. Further studies in LNCaP cells revealed that CsA and FK506 were able to block or attenuate several stages of AR signaling, including hormone binding, nuclear translocation, and activity at several AR-responsive reporter and endogenous genes. These findings provide the first evidence that CsA and FK506 can negatively modulate proliferation of prostate cells in vitro. Immunophilins may now serve as new targets to disrupt AR-mediated prostate cancer growth.
A Novel Real-Time Reference Key Frame Scan Matching Method (2017)

Unmanned aerial vehicles represent an effective technology for indoor search and rescue operations. Typically, most indoor missions' environments would be unknown, unstructured, and/or dynamic. Navigation of UAVs in such environments is addressed by simultaneous localization and mapping approach using either local or global approaches. Both approaches suffer from accumulated errors and high processing time due to the iterative nature of the scan matching method. Moreover, point-to-point scan matching is prone to outlier association processes. This paper proposes a low-cost novel method for 2D real-time scan matching based on a reference key frame (RKF). RKF is a hybrid scan matching technique comprised of feature-to-feature and point-to-point approaches. This algorithm aims at mitigating errors accumulation using the key frame technique, which is inspired from video streaming broadcast process. The algorithm depends on the iterative closest point algorithm during the lack of linear features which is typically exhibited in unstructured environments. The algorithm switches back to the RKF once linear features are detected. To validate and evaluate the algorithm, the mapping performance and time consumption are compared with various algorithms in static and dynamic environments. The performance of the algorithm exhibits promising navigational, mapping results and very short computational time, that indicates the potential use of the new algorithm with real-time systems.