gebhart/patrepeval huggingface dataset:
Measuring salt and freezing temperature on roads (1997)

Abstract Practical monitoring of the amount of salt spread on the road surface for de‐icing purposes is technically difficult, especially if it has to be done in a commercially viable way. Possible solutions to this problem are discussed. As it has become customary to refer to the freezing temperature of a salted road, the physical meaning of such a temperature is scrutinised. It turns out that the meaning and the definition of freezing temperature are not clear, and that it also does not have the significance that is often associated with it. Some experimental results of salt measurements on a road are presented. Copyright © 1997 Royal Meteorological Society.
Evaluation of an antimicrobial soap formula for virucidal efficacy in vitro against human immunodeficiency virus in a blood-virus mixture (1989)

The virucidal efficacy of a health care personnel hand wash product containing 0.5% parachlorometaxylenol in a sodium C14-16 olefin sulfonate formula was evaluated in in vitro tests with human immunodeficiency virus type 1 (HIV-1) in the presence of 50% whole human blood. The HTLV-IIIRF strain of HIV-1 was suspended in 50% medium-50% whole human blood and exposed to various dilutions of the hand wash product for 30 or 60 s. Following detoxification, residual infectivity was determined by a lytic cytopathogenic assay in MT2 cell cultures. No infectious HIV could be detected after a 30-s exposure to the hand wash product at dilutions of 1:5 and 1:10 and after a 60-s exposure at dilutions of 1:5, 1:10, 1:20, and 1:30. More than 99.9% of the virus was inactivated at these dilutions and exposure times.
Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p (1998)

We have sequenced the entire coding region of the human ABC transporter ABC7. The protein represents a 'half-transporter' and displays high sequence similarity to the mouse ABC7 protein and to the mitochondrial ABC transporter Atm1p of Saccharomyces cerevisiae. As shown by immunostaining using a specific antibody, the human ABC7 protein (hABC7) is a constituent of mitochondria. The N-terminus of hABC7 contains the information for targeting and import into the organelles. When synthesised in yeast cells defective in Atm1p (strain delta atm1/hABC7), hABC7 protein can revert the strong growth defect observed for delta atm1 cells to near wild-type behaviour. The known phenotypical consequences of inactivation of the ATM1 gene are almost fully amended by expression of hABC7 protein. delta atm1/hABC7 cells harbour wild-type levels of cytochromes and extra-mitochondrial heme-containing proteins, they contain normal levels of mitochondrial iron, and the cellular content of glutathione is substantially reduced relative to the high levels detected in delta atm1 cells. Our results suggest that hABC7 is a mitochondrial protein, and represents the functional orthologue of yeast Atm1p.
Crowdsourcing for search and data mining (2011)

The Crowdsourcing for Search and Data Mining (CSDM 2011) workshop was held on February 9, 2011 in Hong Kong, China, in conjunction with the Fourth ACM International Conference onWeb Search and Data Mining (WSDM2011). The workshop addressed recent advances in theory and empirical methods, as well as novel applications, in crowdsourcing for search and data mining. Three invited talks were presented, along with eight refereed papers. Workshop proceedings and presentation slides can be found online.
Detection of unknown signals in unknown, non-stationary noise (2009)

This work considers the problem of low-latency detection of unknown signals that appear intermittently in noise having unknown and perhaps non-stationary statistics. We show how to realize a detector having a guaranteed probability of false alarm with best in-class probability of detection and lowest complexity. The detector adaptation is based on a state-machine driven feedback path that selectively extracts the noise statistics required for setting a test threshold. Performance and complexity comparisons are made between the new detector, existing detectors in its class, and the ideal (clairvoyant) detector.
A convenient synthesis of 3-acylindoles via Friedel Crafts acylation of 1-(phenylsulfonyl)indole. A new route to pyridocarbazole-5,11-quinones and ellipticine (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA convenient synthesis of 3-acylindoles via Friedel Crafts acylation of 1-(phenylsulfonyl)indole. A new route to pyridocarbazole-5,11-quinones and ellipticineDaniel M. Ketcha and Gordon W. GribbleCite this: J. Org. Chem. 1985, 50, 26, 5451–5457Publication Date (Print):December 1, 1985Publication History Published online1 May 2002Published inissue 1 December 1985https://pubs.acs.org/doi/10.1021/jo00350a001https://doi.org/10.1021/jo00350a001research-articleACS PublicationsRequest reuse permissionsArticle Views3576Altmetric-Citations176LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
BACTERIAL FLAGELLA (1977)

Flagella are responsible for bacterial motility and chemotaxis. They are subcellular\norgandies that originate in the membrane of the cell and extend 15-20 µm from\nthe cell surface. The bacterial flagellar system has been studied from a variety of\npoints of view, including as a model for the regulation of organelle formation and\nmorphogenesis, as a system that transduces chemical energy into motion, and as the\nbasic effector involved in chemotaxis. To frame precise questions in each of these\nareas, it is necessary that a great deal be known about the nature of the components\nand the behavior of the system. Recent work has led to a clearer characterization\nof structure and function of bacterial flagella in Escherichia coli and in Salmonella.\nOur objective in this review is to summarize the status of current work, as well as\nto identify some of the new questions this work raises. We are selective, particularly\nin the area of chemotaxis since comprehensive reviews of recent (4, 25, 85, 101)\nwell as earlier work (24) in this area have appeared. Flagellar assembly and the regulation of flagella formation have received somewhat less attention. The most\nrecent extensive reviews were by Iino (63) and Doetsch & Hageage (47).
Automatically Categorizing Written Texts by Author Gender (2002)

The problem of automatically determining the gender of a document's author would appear to be a more subtle problem than those of categorization by topic or authorship attribution. Nevertheless, it is shown that automated text categorization techniques can exploit combinations of simple lexical and syntactic features to infer the gender of the author of an unseen formal written document with approximately 80 per cent accuracy. The same techniques can be used to determine if a document is fiction or non‐fiction with approximately 98 per cent accuracy.
24 nm Wavelength Tunable High Duty-Cycle, Self-Starting Figure-eight Fiber Laser (2010)

The operation of a 24nm wavelength tunable self-starting, passively harmonic modelocked, figure-eight laser is experimentally demonstrated. Stable pulses with near half duty-cycle are produced at repetition rates of up to 2.72GHz at 1550nm wavelength.
Sodium butyrate‐treated embryonic stem cells yield hepatocyte‐like cells expressing a glycolytic phenotype (2006)

Embryonic stem cells serve as a promising technology to obtain specific cell types for a number of biomedical applications. Because traditional techniques, such as embryoid body formation result in a wide array of differentiated cells such as hepatic, neuronal, and cardiac lineages, strategies have been utilized which favor cell-specific differentiation to generate more uniformity. In the present study, we have investigated the use of sodium butyrate in a monolayer culture configuration to mediate hepatocyte differentiation of murine embryonic stem cells. Several functional assays used to characterize hepatocyte function (viz. urea secretion, intracellular albumin content, cytokeratin 18, and glycogen staining) were used to analyze the differentiating cell population, suggesting the presence of an enriched population of hepatocyte-like cells. Since mature hepatocytes mediate energy metabolism predominantly through oxidative means as opposed to hepatocyte precursors, which are primarily glycolytic, we have performed a kinetic analysis of glycolytic and functional capacity to characterize the differentiated cells. In conjunction with mitochondrial mass and activity measurements, we show that Na-butyrate-mediated differentiated cells mediate energy metabolism predominantly through glycolysis. This metabolic and mitochondrial characterization can assist in evaluating stem cell differentiation and may prove useful in identifying key regulatory molecules in mediating further differentiation.
A Single-Stage Primary-Side-Controlled Off-line Flyback LED Driver With Ripple Cancellation (2016)

Ripple cancellation LED driver can achieve flicker-free LED driving while maintaining high power factor, high efficiency, and low component cost. It is a very competitive solution compared to a conventional single-stage or two-stage LED driver design. In this paper, a primary-side-controlled ripple cancellation LED driver has been proposed. The voltages of the proposed LED driver are sensed at the primary side by transformer sensing windings. The LED current is also obtained by sensing the primary-side switching current. The entire control circuit is built on the primary side. All the advantages from the existing ripple cancellation LED drivers are maintained while achieving the primary-side control. Based on the proposed circuit, a potential integrated primary-side controller can be designed, which can significantly reduce the component cost and design complexity. A 30-W, 50-V, 0.6-A experimental prototype with a universal input voltage range has been built to verify the proposed LED driver.
A multidisciplinary evidence-based guideline for minimally invasive surgery. (2012)

The Dutch Society for Endoscopic Surgery together with the Dutch Society of Obstetrics and Gynecology initiated a multidisciplinary working group to develop a guideline on minimally invasive surgery to formulate multidisciplinary agreements for minimally invasive surgery aiming towards better patient care and safety. The guideline development group consisted of general surgeons, gynecologists, an anesthesiologist, and urologist authorized by their scientific professional association. Two advisors in evidence-based guideline development supported the group. The guideline was developed using the "Appraisal of Guidelines for Research and Evaluation" instrument. Clinically important aspects were identified and discussed. The best available evidence on these aspects was gathered by systematic review. Recommendations for clinical practice were formulated based on the evidence and a consensus of expert opinion. The guideline was externally reviewed by members of the participating scientific associations and their feedback was integrated. Identified important topics were: laparoscopic entry techniques, intra-abdominal pressure, trocar use, electrosurgical techniques, prevention of trocar site herniation, patient positioning, anesthesiology, perioperative care, patient information, multidisciplinary user consultation, and complication registration. The text of each topic contains an introduction with an explanation of the problem and a summary of the current literature. Each topic was discussed, considerations were evaluated and recommendations were formulated. The development of a guideline on a multidisciplinary level facilitated a broad and rich discussion, which resulted in a very complete and implementable guideline.
Amino acids and peptides. XIII. Synthesis of a nonacosapeptide corresponding to the N-terminal sequence 1-29 (.BETA.-fragment) of human liver metallothionein II (hMT II) and its heavy metal-binding properties. (1986)

A nonacosapeptide corresponding to the N-terminal sequence 1-29 (β-fragment) of human liver metallothionein II (hMT II) was synthesized by the azide coupling of five peptide fragments [1, 2, 4, 6 and 8], followed by HF deprotection and its heavy metal-binding properties were examined. It was revealed that the Cd-binding ability of the synthetic β-fragment as well as synthetic α-fragment corresponding to the C-terminal sequence 30-61 of hMT II was stronger than that of native rat thionein. Moreover, it was found that both the α-and β-fragments bound preferentially to Cu ions rather than Cd ions.
Characterization of a Leucine Zipper-containing Protein Identified by Retroviral Insertion in Avian Neuroretina Cells (1996)

We reported previously that post-mitotic chicken embryonic neuroretina (NR) cells are induced to proliferate following in vitro infection with RAV-1, a retrovirus that does not carry an oncogene. NR cell multiplication results from the frequent activation and subsequent retroviral transduction of two related serine/threonine protein kinases, the c-mil/c-raf or c-Rmil/B-raf genes. We also showed that a very early event in the activation of these proto-oncogenes is the synthesis of chimeric mRNAs containing viral and cellular sequences joined by a splicing mechanism. In the current study, we have examined the ability of RAV-1 to induce proliferation of quail NR cells. By using the reverse transcription-polymerase chain reaction technique, we identified, in several proliferating quail NR cultures infected with RAV-1, a chimeric mRNA containing cellular sequences joined to the RAV-1 splice donor site. These cellular sequences are derived from a gene designated R10, which is expressed through a 1.9-kilobase (kb) mRNA detected in several embryonic tissues. A second transcript of 2.3 kb is specifically expressed in the NR, where both transcripts are developmentally regulated. The R10 cDNA encodes a 251-amino acid polypeptide that contains a leucine zipper motif. It exhibits significant similarity with the putative D52/N8L protein, encoded by an mRNA reported previously to be overexpressed in human breast and lung carcinomas. By using polyclonal antibodies specific for its amino-terminal and leucine zipper-containing regions, we identified the R10 gene product as a cytoplasmic protein of 23 kDa in cultured avian fibroblasts. A second protein of 30 kDa is detected in post-mitotic NR cells that express the 2.3-kb transcript. We also show, by in vitro transcription/translation and immunoprecipitation, that the R10 protein can readily form homodimers, presumably through its leucine zipper motif.
Polycrystalline silicon–germanium films on oxide using plasma-enhanced very-low-pressure chemical vapor deposition (1995)

Si1−xGex thin films on oxide-coated Si substrates have been formed by plasma-enhanced very-low-pressure chemical vapor deposition. Two modes of deposition, thermal and plasma enhanced, were studied using SiH4 and GeH4 at temperatures ≤600 °C. In both cases, growth rates and grain sizes increase with Ge content, and the polycrystalline-to-amorphous transition temperature is lower for Si1−xGex than Si. Compared to thermal growth of polycrystalline Si1−xGex, plasma-enhanced deposition of poly-Si1−xGex promotes higher growth rates, smaller grain sizes, and direct deposition onto oxide, as well as improved structural properties such as a smoother surface and a more columnar grain texture. Plasma deposition of amorphous-Si1−xGex films followed by a crystallization anneal at 600 °C results in an even smoother surface morphology with grain sizes enhanced by an order of magnitude compared to plasma-deposited poly-Si1−xGex films.
Expression of human estrogen receptor-α and -β, progesterone receptor, and androgen receptor mRNA in normal and malignant ovarian epithelial cells (1999)

Our understanding of the roles played by sex hormones in ovarian carcinogenesis has been limited by a lack of data concerning the mode of sex hormone action in human ovarian surface epithelial (HOSE) cells, the tissue of origin of >90% of ovarian cancers. We have compared the relative abundance of estrogen receptor (ER)alpha, ERbeta, progesterone receptor (PR), and androgen receptor (AR) mRNA in four primary cultures of HOSE cells obtained from postmenopausal women to those found in late serous adenocarcinoma primary cell cultures and established ovarian cancer cell lines. We observed coexpression of ERalpha and ERbeta mRNA along with AR and PR transcripts in normal HOSE cells and disruption of ERalpha mRNA expression as well as dramatic down-regulation of PR and AR transcript expression in most ovarian cancer cells. In contrast, levels of ERbeta mRNA were unaffected by the malignant state. Additionally, a novel mutation involving a 32-bp deletion in exon 1 of ERalpha transcripts was detected in the SKOV3 cell line. This mutation would explain why SKOV3 was reported to be ER-positive but estrogen-insensitive. Taken together, these findings suggest that estrogens, signaling via either or both ER subtypes, may play an indispensable role in regulating normal HOSE cell functions. Therefore, loss of ERalpha, PR, and AR mRNA expression in HOSE cells may be responsible for neoplastic transformation in this cell type. In contrast, the roles played by ERbeta in normal and malignant HOSE cells remain elusive. Finally, the coexistence of mutated ERalpha mRNA and normal ERbeta transcripts in SKOV3 argues in favor of a dependency of ERbeta action on functional ERalphas.
A Sketching Interface for Modeling and Editing Hairstyles (2005)

This paper presents interaction techniques and algorithms for modeling and editing virtual 3D hairstyles with a user-friendly sketching interface. Using a pressure-sensitive tablet, a user makes freeform strokes to mimic a number of real-world hairstyling operations such as cutting, combing, curling, frizzing, and twisting. Additionally, the user can perform other localized operations such as implanting new hair strands onto a 3D surface (usually the scalp), lengthening the strands, and adjusting hair density. Virtual hairpins can also be placed onto strands to temporarily fix the position of hair which allows for the creation of more advanced styles such as ponytails. The system runs at interactive rates, thereby providing instant visual feedback to users as they work. Unlike existing hair modeling systems that require hours of complicated control point manipulations and parameter tweaking, our interface allows for creating expressive hairstyles quickly and easily, even for first-time users.
Gaining Flexibility and Performance of Computing Using Tailored Instruction Set and Reconfigurable Architecture (2008)

As data transfer rates become higher, general processor is not competent for works with high computing intensity in wireless communication area. The other hand, existing baseband processors lack adaptive ability to support new applications and newer versions of existing application. Thus the paper puts forward a novel architecture of reconfigurable stream processor along with application-specific instruction set for software radio. The main goal of the processor is to point out an effective way to designing hardware of software radio with high computational performance and adaptive ability. We achieve this by analyzing multi-stream modalities of advanced wireless communication standards, such as 3G and WLAN. Simulation results show that the processor with powerful calculational capability can adapt to applications of wireless communication area easily.
Increasing relevance of pharmacogenetics of drug metabolism in clinical practice (2001)

Much of the individual variation in drug response is due to genetic drug metabolic polymorphisms. Clinically relevant examples include acetylator status; cytochrome P450 2D6, 2C9 and 2C19 polymorphisms; and thiopurine methyltransferase deficiency. It is important to be aware of which drugs are subject to pharmacogenetic variability. In the future, population-based pharmacogenetic testing will allow more individualized drug treatment and will avoid the current empiricism.
Aircraft Electrical and Electronic Systems (2009)

The Aircraft Engineering Principles and Practice Series provides students, apprentices and practicing aerospace professionals with the definitive resources to take forward their aircraft engineering maintenance studies and career. This book provides a detailed introduction to the principles of aircraft electrical and electronic systems. It delivers the essential principles and knowledge required by certifying mechanics, technicians and engineers engaged in engineering maintenance on commercial aircraft and in general aviation. It is well suited for anyone pursuing a career in aircraft maintenance engineering or a related aerospace engineering discipline, and in particular those studying for licensed aircraft maintenance engineer status. The book systematically covers the avionic content of EASA Part-66 modules 11 and 13 syllabus, and is ideal for anyone studying as part of an EASA and FAR-147 approved course in aerospace engineering.All the necessary mathematical, electrical and electronic principles are explained clearly and in-depth, meeting the requirements of EASA Part-66 modules, City and Guilds Aerospace Engineering modules, BTEC National Units, elements of BTEC Higher National Units, and a Foundation Degree in aircraft maintenance engineering or a related discipline.