gebhart/patrepeval huggingface dataset:
[Inhibition of aromatics on ammonia-oxidizing activity of sediment]. (2004)

The inhibition of 24 aromatics on ammonia-oxidizing activity of nitrifying bacteria in sediment was measured. The effects of the kind, number and position of substituted groups on ammonia-oxidizing activity of nitrifying bacteria were discussed. The inhibition of mono-substituted benzenes on ammonia-oxidizing activity of nitrifying bacteria were in order of -OH > -NO2 > -NH2 > -Cl > -CH3 > -H. The position of substituted groups of di-substituted benzenes also affected the inhibition, and the inhibitions of dimethylbenzenes(xylene) were in order of meta-> ortho-> para-. The increase in number of substituted group on benzene-ring enhanced the inhibition of aromatics studied in this study on nitrifying bacteria. There was a linear relationship between inhibition (IC50, mumol.L-1) of aromatics on ammonia-oxidizing activity and total electronegativity (sigma E) of aromatics: lgIC50 = 14.72 - 0.91 sigma E.
Significance of Non-Fourier Heat Waves in Conduction (1994)

Technical Briefs Significance of Non-Fourier Heat Waves in Conduction Ali Vedavarz, Ali Vedavarz Department of Mechanical Engineering, Polytechnic University, 333 Jay Street, Brooklyn, NY 11201 Search for other works by this author on: This Site PubMed Google Scholar Sunil Kumar, Sunil Kumar Department of Mechanical Engineering, Polytechnic University, 333 Jay Street, Brooklyn, NY 11201 Search for other works by this author on: This Site PubMed Google Scholar M. Karim Moallemi M. Karim Moallemi Department of Mechanical Engineering, Polytechnic University, 333 Jay Street, Brooklyn, NY 11201 Search for other works by this author on: This Site PubMed Google Scholar Author and Article Information Ali Vedavarz Department of Mechanical Engineering, Polytechnic University, 333 Jay Street, Brooklyn, NY 11201 Sunil Kumar Department of Mechanical Engineering, Polytechnic University, 333 Jay Street, Brooklyn, NY 11201 M. Karim Moallemi Department of Mechanical Engineering, Polytechnic University, 333 Jay Street, Brooklyn, NY 11201 J. Heat Transfer. Feb 1994, 116(1): 221-224 (4 pages) https://doi.org/10.1115/1.2910859 Published Online: February 1, 1994 Article history Received: June 1, 1992 Revised: June 1, 1993 Online: May 23, 2008
An Autoregulatory Mechanism Governing Mucociliary Transport Is Sensitive to Mucus Load (2014)

Mucociliary clearance, characterized by mucus secretion and its conveyance by ciliary action, is a fundamental physiological process that plays an important role in host defense. Although it is known that ciliary activity changes with chemical and mechanical stimuli, the autoregulatory mechanisms that govern ciliary activity and mucus transport in response to normal and pathophysiological variations in mucus are not clear. We have developed a high-speed, 1-μm-resolution, cross-sectional imaging modality, termed micro-optical coherence tomography (μOCT), which provides the first integrated view of the functional microanatomy of the epithelial surface. We monitored invasion of the periciliary liquid (PCL) layer by mucus in fully differentiated human bronchial epithelial cultures and full thickness swine trachea using μOCT. We further monitored mucociliary transport (MCT) and intracellular calcium concentration simultaneously during invasion of the PCL layer by mucus using colocalized μOCT and confocal fluorescence microscopy in cell cultures. Ciliary beating and mucus transport are up-regulated via a calcium-dependent pathway when mucus causes a reduction in the PCL layer and cilia height. When the load exceeds a physiological limit of approximately 2 μm, this gravity-independent autoregulatory mechanism can no longer compensate, resulting in diminished ciliary motion and abrogation of stimulated MCT. A fundamental integrated mechanism with specific operating limits governs MCT in the lung and fails when periciliary layer compression and mucus viscosity exceeds normal physiologic limits.
Cyclic AMP-dependent protein kinase in canine pancreatic rough endoplasmic reticulum (1989)

A canine pancreas homogenate was subfractionated by several differential centrifugation steps. The distribution of cAMP-dependent protein kinase in the various fractions was monitored by assaying [3H]cAMP binding and photo-cross-linking of the regulatory subunits of the enzyme (RI and RII) with radiolabeled 8-azido-cAMP. The distribution of the kinase was also compared to that of markers for the plasma membrane, the endoplasmic reticulum and the cytosol. While our results confirm previous studies suggesting the presence of cyclic AMP-dependent protein kinase in the cytosol and Golgi, a significant amount of the total [3H] cAMP binding and photolabeled R subunits (both RI and RII) were found in rough microsomes (RM). The association is relatively resistant to extraction with EDTA, low and high ionic strength solutions. These extractions unmasked several new phosphorylation substrates in the "stripped" RM that were inaccessible in the RM, possibly because they were covered by ribosomes or peripheral membrane proteins. RII with a molecular mass of 52 kDa (RII-52 kDa) was the predominant RII found in the cytosolic fraction, whereas RII-52 kDa and RII with a molecular mass of 54 kDa (RII-54 kDa) were approximately equally enriched in the RM fraction. The mobility of the RII-52 kDa-photolabeled band could be shifted to the mobility of the RII-54 kDa band by phosphorylation with purified catalytic subunit and ATP, indicating that they represent "dephospho" and "phospho" forms of RII, respectively. A more precise localization to the rough endoplasmic reticulum was accomplished by isopycnic floatation in sucrose gradients. The enzyme cobanded at the density of rough microsomes and shifted to the lower density of "stripped" microsomes after treatment with puromycin/high salt, which specifically removes ribosomes.
Efficacious cleavage of the benzyl ether protecting group by electrochemical oxidation (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEfficacious cleavage of the benzyl ether protecting group by electrochemical oxidationSteven M. Weinreb, Gary A. Epling, Richard Comi, and Michael ReitanoCite this: J. Org. Chem. 1975, 40, 9, 1356–1358Publication Date (Print):May 1, 1975Publication History Published online1 May 2002Published inissue 1 May 1975https://pubs.acs.org/doi/10.1021/jo00897a043https://doi.org/10.1021/jo00897a043research-articleACS PublicationsRequest reuse permissionsArticle Views895Altmetric-Citations48LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Radiologic image compression-a review (1995)

The objective of radiologic image compression is to reduce the data volume of and to achieve a low bit rate in the digital representation of radiologic images without perceived loss of image quality. However, the demand for transmission bandwidth and storage space in the digital radiology environment, especially picture archiving and communication systems (PACS) and teleradiology, and the proliferating use of various imaging modalities, such as magnetic resonance imaging, computed tomography, ultrasonography, nuclear medicine, computed radiography, and digital subtraction angiography, continue to outstrip the capabilities of existing technologies. The availability of lossy coding techniques for clinical diagnoses further implicates many complex legal and regulatory issues. This paper reviews the recent progress of lossless and lossy radiologic image compression and presents the legal challenges of using lossy compression of medical records. To do so, we first describe the fundamental concepts of radiologic imaging and digitization. Then, we examine current compression technology in the field of medical imaging and discuss important regulatory policies and legal questions facing the use of compression in this field. We conclude with a summary of future challenges and research directions.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Patient Characteristics and Risks Factors for Development of Dependence on Hydrocodone and Oxycodone (2004)

The purpose of the study was to document the substantial increase in problematic use of hydrocodone and oxycodone in an addiction treatment population. Our study consisted of a retrospective review of medical records from all patients admitted and discharged in 2000 from Sparrow/St. Lawrence Addiction Detoxification Unit (N = 534). A literature review was conducted in medical journals, governmental groups, and reports including Drug Abuse Warning Network, Pharmacy Times, and National Household Survey on Drug Abuse. More than 144 patients (27%) were dependent on prescription opiate medications. The most frequently mentioned medication was Vicodin (hydrocodone) (53% of the users) followed by OxyContin (oxycodone) (19%). Physicians commonly prescribed these medications (75% of the cases). Predictors of dependence on opiate medications included substance-related diagnoses, positive toxicology for opiates, and other medical diagnoses. Patients under the care of physicians who have other drug dependence diagnoses and medical complaints appear at risk of developing dependence on prescription opiate medications. Proper evaluation and intervention can limit adverse consequences of prescription opiate medications.
Distinct substrate preference of human and mouse <i>N</i>-methylpurine-DNA glycosylases (1996)

N-Methylpurine-DNA glycosylase (MPG), a ubiquitous DNA repair protein, removes several N-alkylpurine adducts, hypoxanthine, cyclic ethenoadducts of adenine, guanine and cytosine and 8-oxoguanine from DNA. The recombinant human and mouse MPGs, purified from Escherichia coli, show a significant difference in substrate preference. While both proteins prefer 3-methyladenine over other N-alkylpurines in DNA, the mouse MPG removes 7-methylguanine and 3-methylguanine at an approximately 2- to 3-fold higher rate than the human protein when adjusted for equal activity for the release of 3-methyladenine from DNA. Hybrid recombinant proteins containing N-terminal and C-terminal halves of the human and mouse glycosylases were partially purified from MPG-negative E.coli. Their substrate preferences suggest that the N-terminal half is more critical for the recognition of 3-methylguanine and 7-methylguanine.
Reaction of Mercaptans with Unsaturated Compounds (1948)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReaction of Mercaptans with Unsaturated CompoundsJ. Lester Szabo and Eric T. StillerCite this: J. Am. Chem. Soc. 1948, 70, 11, 3667–3668Publication Date (Print):November 1, 1948Publication History Published online1 May 2002Published inissue 1 November 1948https://pubs.acs.org/doi/10.1021/ja01191a037https://doi.org/10.1021/ja01191a037research-articleACS PublicationsRequest reuse permissionsArticle Views243Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A mobile agent architecture for distributed information management (1997)

Large-scale networked environments, such as the Internet, possess the characteristics of distributed data, distributed access and distributed control; this gives the user a powerful mechanism for building and integrating large repositories of distributed information from diverse resources. However, few support tools have been developed to allow the user to take advantage of the distributed nature of their information. To help address this problem, we advocate the integration of two technologies; distributed information management principles to allow users to create, disseminate, discover and manage their information, and mobile agent technology to provide the flexibility, scalability and dynamism necessary to develop such distributed information management applications. We present four principles that we have identified as being key to achieving distributed information management and an architecture where mobile agents can move across distributed environments, integrate with local resources and other mobile agents, and communicate their results back to the user. We also describe a number of prototype distributed information management agents that we have developed.
Wireless technology identification using deep Convolutional Neural Networks (2017)

With the proliferation of wireless technologies and the ever-increasing growth in Internet of Things (IoT) devices operating the license-free Industrial, Scientific, and Medical (ISM) band, intelligent access systems capable of coexisting in crowded spectrum regions are of vital importance. In this work we study the adaptation of Convolutional Neural Networks (CNNs) to the problem of identifying coexisting wireless devices. We develop a machine learning conduit to facilitate the detection and identification of frequency domain signatures for 802.x standard compliant technologies. Spectrum scans across the entire ISM region (80-MHz) are recorded and a data-driven training process for a wide range of Signal-to-Noise Ratios (SNRs) is completed. Model accuracy is compared to that attained using standard feature based classification methods. Results indicate CNN models outperform their counterpart methods in terms of classification accuracy, connoting them to be highly effective tools for detecting and identifying coexisting devices despite acute overlap and interference presence. The proposed approach aims to advance cognitive wireless awareness by enhancing automatic detection and identification accuracy.
Molecular cloning and characterization of human eosinophil Charcot-Leyden crystal protein (lysophospholipase). Similarities to IgE binding proteins and the S-type animal lectin superfamily (1993)

We have isolated and sequenced a 598-bp full length cDNA clone for the human Charcot-Leyden crystal (CLC) protein (eosinophil lysophospholipase), the unique and prominent constituent of human eosinophils and basophils that forms the hexagonal bipyramidal crystals classically observed in tissues and secretions from sites of eosinophil-associated inflammation. A 426-bp open reading frame encoded a 142-amino acid polypeptide with a predicted molecular mass of 16.5 kDa and isoelectric point of 7.28. The deduced amino acid sequence of CLC protein showed 20 to 30% similarity over regions of approximately 100 amino acids with the carboxyl-terminal domains of four IgE-binding proteins, including the 31-kDa human and rat IgE-binding proteins, the 35-kDa mouse carbohydrate binding protein (CBP35), Mac-2, the murine macrophage cell surface protein that is identical to CBP35, and the human homologue of Mac-2. These proteins are members of a superfamily of beta-galactoside binding S-type animal lectins, which includes a group of highly conserved 14-kDa lectins isolated from human lung, heart, placenta, bovine heart, chicken skin, mouse fibroblasts, and the electric organ of the electric eel; CLC protein also showed sequence similarities to these 14-kDa animal lectins, including conservation of 7 of 16 invariant amino acid residues thought to comprise the carbohydrate-binding domain of these proteins, with conservative amino acid changes at others; thus, CLC protein could potentially possess carbohydrate or IgE-binding activities. Northern analyses revealed an approximately 900-bp mRNA species that was present in peripheral blood eosinophils from patients with eosinophilia, basophils from patients with chronic myelogenous leukemia, and in HL-60 cells induced towards eosinophilic differentiation with B cell growth factor-II (IL-5) or granulocytic differentiation with DMSO, but was absent in neutrophils, monocytes, T cells, B cells, or HL-60 cells induced towards monocytic differentiation with vitamin D3. Southern analyses revealed a gene of approximately 5 to 6 kb in length. The cDNA clone and complete amino acid sequence data for CLC protein will facilitate structure-function analyses of its unusual hydrophobic properties, unique propensity for crystallization, lysophospholipase, and potential lectin-like activities.
Women Managers, Gendered Cultural Processes and Organizational Change (1996)

This paper develops a critical approach towards the nature of research and knowledge about Women in Management (WIM). A variety of perspectives in the WIM area are reviewed from an inter‐disciplinary standpoint. Drawing on radical approaches to organization analysis, the paper aims to evaluate the insights provided into the position of women in management from the perspectives outlined. It is argued that feminist approaches which focus on the gendered nature of organizational processes and in particular organizational cultures, represent an important way forward in the development of adequate theorizations of the position of women managers. The paper examines the implications of this analysis for the Women in Management research agenda and explores appropriate strategies for organizational change within this arena.
An Update on the Dopaminergic Treatment of Restless Legs Syndrome and Periodic Limb Movement Disorder (2004)

This paper reviews evidence from April, 1998 through April 2002 for the dopaminergic treatment of the restless legs syndrome (RLS) and periodic limb movement disorder (PLMD). There has been increased study of dopaminergic agents for the treatment of these conditions since publication of a review paper and practice parameters that covered all types of medical treatment of RLS and PLMD in 1999. For this reason, the Restless Legs Syndrome Task Force and the Standards of Practice Committee decided to update the evidence on dopaminergic treatment of these conditions. This paper reviews the literature on levodopa, dopaminergic agonists (pergolide, pramipexole, ropinirole, talipexole, cabergoline, piribidel, DHEC), and other dopaminergic agents (amantadine, selegiline).
Resection of Borderline Resectable and Locally Advanced Pancreatic Adenocarcinomas after Neoadjuvant Chemotherapy (2015)

Curative intent resection in BL and LA cancer patients after neoadjuvant chemotherapy can be achieved with reasonable mortality and morbidity and an encouraging 3-year survival. After neoadjuvant therapy, resection provides a better overall survival for BL compared to LA cancer patients.
Chromatographic properties of composite chiral stationary phases based on cellulose derivatives (1995)

Abstract Chiral stationary phases (CSPs) prepared by mixing together two different cellulose derivatives, before or after being coated on macroporous silica gel, were developed in order to determine the mutual influence of two different polymers on global chiral recognition capacity. The chromatographic properties of these CSPs were evaluated using a wide range of racemic test solutes. The mixing method does not significantly affect the enantioselectivities. The composite CSPs obtained by cocoating of two different cellulose derivatives on silica generally exhibit chiral recognition capacities intermediate between those of the two individual phases, and thus broadening the application range of a single column. These results indicate that the simultaneous coating of two different cellulose derivatives does not significantly alter the optical resolution power of each chiral material and are discussed in relationship with the supramolecular structure of the polymeric stationary phases. © 1995 Wiley‐Liss, Inc.
Hybrid Recommender System Using Latent Features (2009)

This paper proposes a hybrid recommender system that utilizes latent features. The main problem discussed in this paper is the cold start problem. To handle this problem, the proposed system first extracts latent features from items represented by a multi-attributed record using a probabilistic model. Then, it calculates the similarity of users from their ratings. Both similarities between items and users are used for predicting unknown rating of a user to a item. We evaluate the proposed method using a movie data set and shows that the proposed method achieves good performance for small ratings information.
Energy transfer at optical frequencies to silicon-based waveguiding structures (2001)

For decades, crystalline silicon (Si) has been the semiconductor of choice for the majority of applications in microelectronics. Recent advances in material science have focused attention on the silicon-on-insulator (SOI) platform, a submicrometer-thick layer of single crystal Si resting on an insulating silicon dioxide (SiO2) layer. Here we calculate the lifetime of an electric dipole moment oscillating in the cover region of several canonical Si waveguiding structures. We show that the vicinity just above SOI produces the most dramatic changes to the radiative lifetime and thus the power spectrum of the emitting dipole. We demonstrate that SOI stands apart from other Si-based optoelectronic platforms in its ability to transport energy, in the form of light, away from an oscillating electric dipole via highly localized, optical- and IR-frequency guided waves.
Cinemicrography of mouse oocyte maturation utilizing nomarski differential‐interference microscopy (1973)

Abstract The analysis of in vitro mouse oocyte maturation using Nomarski differential‐interference optics and time‐lapse cinemicrography provides information on the morphological events of oocyte maturation and their duration with greater precision than previously available. Furthermore, some previously unreported morphological events are described. The breakdown of the germinal vesicle was preceded for 41 minutes by extreme activity of the germinal vesicle membrane. The perivitelline space formed precociously by expansion of the zona pellucida rather than by shrinkage of the oocyte. Condensation of the bivalents, centromeric repulsion, formation of the metaphase I plate, and growth of the spindle apparatus were observed. Metaphase I, defined as the period from formation of the metaphase plate to the beginning of anaphase, lasted four hours and twenty‐seven minutes. Anaphase chromosome separation began 11 hours and 15 minutes after disintegration of the nucleolus, and was complete within ten minutes. Polar body formation began before the completion of anaphase. The mid‐body formed between the separating anaphase dyads, and moved with the telophase spindle to the newly formed oocyte‐polar body boundary.