gebhart/patrepeval huggingface dataset:
The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse (2003)

Liver X receptor (LXR) ligands are currently being evaluated as potential therapeutic agents for the treatment of low HDL. The LXR ligand T0901317 elevates ATP binding cassette transporter A1 (ABCA1) and HDL levels in animal models and induces moderate lipogenesis through upregulation of sterol regulatory element binding protein 1c (SREBP1c). Because insulin may also regulate lipogenesis through SREBP1c and fatty acid synthase (FAS), we investigated the effect of an LXR ligand in hyperinsulinemic mice. Administration of T0901317 to male db/db mice for 12 days resulted in a more severe hypertriacylglycerolemia and hepatic triacylglycerol accumulation than observed in nondiabetic mice. The LXR target genes ABCA1, SREBP1c, FAS, and stearoyl-CoA desaturase 1 were upregulated by T0901317 treatment in both diabetic db/db and nondiabetic C57BLKS mice. Changes in lipogenic gene expression were independent of mouse strain, indicating that the severe lipogenesis observed in LXR ligand-treated db/db mice was not due to additive effects of insulin on lipogenic gene expression. Phosphoenolpyruvate carboxykinase expression was suppressed, suggesting that a shift from gluconeogenesis toward lipogenesis could partially explain our observations in db/db mice. Our data suggest that LXR ligands that have effects on both fatty acid and carbohydrate metabolism should be carefully evaluated in obesity, insulin, and leptin resistance.
Application Properties of Ultra Light Weight Silica Aerogel to Polyurethane Membrane (2013)

Application properties of ultra light weight silica aerogel toward polyurethane membranes were investigated. From the results of pre-milling process of the silica aerogel, the solvent for dispersion of the aerogel was determined for methyl ethyl ketone and its content in the solvent was determined by 30%. Using this aerogel dispersion, the polyurethane membranes were prepared according to the mixing amount of silica aerogel and various properties of the membranes were investigated. As results, the optimum mixing amount of silica aerogel inside polyurethane membranes was decided at 11%, because the improvement of light weight property, air permeability, and moisture vapor permeability were improved upto 11% of silica aerogel content, maintaining the water penetration resistance almost unchanged.
The Reaction of Hydrogen Sulfide with Acrylonitrile, Acrylic Ester and Crotonaldehyde (1947)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Reaction of Hydrogen Sulfide with Acrylonitrile, Acrylic Ester and CrotonaldehydeLeon L. Gershbein and Charles D. HurdCite this: J. Am. Chem. Soc. 1947, 69, 2, 241–242Publication Date (Print):February 1, 1947Publication History Published online1 May 2002Published inissue 1 February 1947https://pubs.acs.org/doi/10.1021/ja01194a019https://doi.org/10.1021/ja01194a019research-articleACS PublicationsRequest reuse permissionsArticle Views461Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Continuous FEM simulation of multi-pass plate hot rolling suitable for plate shape analysis (2011)

为了连续地模仿多传递板滚动，处理，一块 3-D 橡皮空转动的模型被建议并且一辆汽车有数据过去的精制网孔的模块被开发并且用 FE 软件综合，马克。空转动的模型有把抵抗和变丑弄弯到真实固体和少得多网孔的相等的僵硬，因此计算时间极大地被减少。基于这些，影响板侧面的因素在滚动和内部通行证的冷却罐头期间的起始的王冠，热王冠和热转移例如弯曲转动的力量，在模拟被考虑。有数据过去的精制网孔的模块能自动地精制并且重编的汽车元素和转移节、元素的结果到新网孔。而且，为常规建模的 3-D 参量地被开发并且能独立于马克预处理节目被运用。一个七通行证的工业热滚动过程连续地被模仿验证模型的精确性。由有工业测量数据，滚动力量，温度和板侧面的计算结果的比较在有测量的好一致。
[The effect of the conditions of the controlled cultivation of Neisseria meningitidis on the lipopolysaccharide yield]. (1996)

The preparations of lipopolysaccharide (LPS) were obtained from N.meningitidis cells grown in synthetic nutrient medium in a fermenter. Different N.meningitidis strains, groups A, B, C, were found to give different yield of the preparation of LPS: the maximum yield was obtained from N.meningitidis cells C 133 and the minimum yield, from N.meningitidis cells B 125. The comparison of group B strains 125 and 150 showed that the former gave a higher yield of LPS. The influence of the phase of growth on the yield of the preparation of LPS obtained from N.meningitidis cells 125 was shown to be manifested under the conditions of oxygen excess; in the exponential phase the highest yield of the preparation was observed. Oxygen dissolved in the medium was found to influence the yield of the preparation of LPS: with the same content of glucose in the medium the yield of LPS was higher under the conditions of the limited concentration of oxygen; with the same concentration of oxygen in the medium the yield of LPS increased with the increase of the concentration of glucose.
Pumping through Porous Hydrophobic/Oleophilic Materials: An Alternative Technology for Oil Spill Remediation (2014)

Recently, porous hydrophobic/oleophilic materials (PHOMs) have been shown to be the most promising candidates for cleaning up oil spills; however, due to their limited absorption capacity, a large quantity of PHOMs would be consumed in oil spill remediation, causing serious economic problems. In addition, the complicated and time-consuming process of oil recovery from these sorbents is also an obstacle to their practical application. To solve the above problems, we apply external pumping on PHOMs to realize the continuous collection of oil spills in situ from the water surface with high speed and efficiency. Based on this novel design, oil/water separation and oil collection can be simultaneously achieved in the remediation of oil spills, and the oil sorption capacity is no longer limited to the volume and weight of the sorption material. This novel external pumping technique may bring PHOMs a step closer to practical application in oil spill remediation.
Effect of styrene‐<i>co</i>‐acrylonitrile on cold crystallization and mechanical properties of poly(ethylene terephthalate) (2012)

Abstract Blends of poly(ethylene terephthalate) (PET) with small amounts of styrene‐ co ‐acrylonitrile (SAN) were prepared by melt blending, and cold crystallization of these mixtures was investigated by means of differential scanning calorimetry. The results suggest that SAN interacts with the amorphous phase of PET, as observed by variations in the glass transition temperature and in the morphology of the blends, analyzed by scanning electron microscopy. The addition of 1% SAN promoted a significant reduction in the crystallization rate of PET, in a manner similar to that of an antinucleating agent. However, the crystallinity of the PET/SAN blends was comparable with that of neat PET; hence, mechanical properties were only slightly affected. Kinetic parameters were determined using Avrami theory; Avrami plots presented a nonlinear behavior at the end of crystallization, indicating that cold crystallization proceeds in two stages. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Determination of Amphetamine and Methylphenidate in Exhaled Breath of Patients Undergoing Attention-Deficit/Hyperactivity Disorder Treatment (2014)

The results confirm that amphetamine is present in exhaled breath after intake and demonstrate for the first time the presence of methylphenidate and ritalinic acid after its intake. This gives further support to the potential use of exhaled breath for detecting drug intake.
Free software toolkit for Japanese large vocabulary continuous speech recognition (2000)

ICSLP2000: the 6th International Conference on Spoken Language Processing, October 16-20, 2000, Beijing, China.
METABOLISM OF L-DOPA AND 5-HTP IN THE PANCREATIC ISLETS OF THE MOUSE STUDIED WITH ELECTRON MICROSCOPIC AUTORADIOGRAPHY (1971)

The cellular and subcellular distribution of radioactivity following injection of 3H-L-DOPA or 3H-5-HTP was studied in mouse pancreatic islets by means of electron microscopic autoradiography. Already 20 min after injection of 3H-5-HTP, autoradiographic silver grains appeared over A2 and B cells while A1 cells did not display any signs of radioactivity at any time investigated (20 min-16 hours), not even when monoamine oxidase was inhibited. Quantitative analysis of autoradiographic sections revealed that the concentration of silver grains over the specific granules of A2 and B cells was 5-10 times higher than over the remaining parts of these cells. In A2 cells the highest grain counts were recorded 20 min after 5-HTP, in B cells 1 hour after the injection of the label. After 8 hours very few and after 16 hours no silver grains appeared over islet cells. Inhibition of monoamine oxidase caused an increased retention of label, most pronounced over A2 cells. Pretreatment with reserpine or an inhibitor of aromatic amino acid decarboxylase prior to the injection of label abolished the autoradiographic reaction, which strongly supports the idea that the great majority of autoradiographic stiver grains observed over the granules of A2 and B cells represent monoamines formed by decarboxylation of the administered precursors. - Administration of 3H-L-DOPA resulted in an essentially similar autoradiographic pattern.
Elevated‐Temperature 3D Printing of Hybrid Solid‐State Electrolyte for Li‐Ion Batteries (2018)

While 3D printing of rechargeable batteries has received immense interest in advancing the next generation of 3D energy storage devices, challenges with the 3D printing of electrolytes still remain. Additional processing steps such as solvent evaporation were required for earlier studies of electrolyte fabrication, which hindered the simultaneous production of electrode and electrolyte in an all-3D-printed battery. Here, a novel method is demonstrated to fabricate hybrid solid-state electrolytes using an elevated-temperature direct ink writing technique without any additional processing steps. The hybrid solid-state electrolyte consists of solid poly(vinylidene fluoride-hexafluoropropylene) matrices and a Li<sup>+</sup> -conducting ionic-liquid electrolyte. The ink is modified by adding nanosized ceramic fillers to achieve the desired rheological properties. The ionic conductivity of the inks is 0.78 × 10 <sup>-3</sup> S cm<sup>-1</sup> . Interestingly, a continuous, thin, and dense layer is discovered to form between the porous electrolyte layer and the electrode, which effectively reduces the interfacial resistance of the solid-state battery. Compared to the traditional methods of solid-state battery assembly, the directly printed electrolyte helps to achieve higher capacities and a better rate performance. The direct fabrication of electrolyte from printable inks at an elevated temperature will shed new light on the design of all-3D-printed batteries for next-generation electronic devices.
Synthese einer kovalenten kohlenhydrat‐protein‐verbindung und ihr verhalten in der ultrazentrifuge und bei der elektrophorese (1961)

Abstract Es wird die Synthese einer kovalenten Verbindung aus Alginsäure (Mol.‐Gew. 47500) und Rinderserumalbumin, reinst, (RSA) (Mol.‐Gew. 64000) nach der Azid‐Methode beschrieben. Das Algicle‐RSA wurde durch fraktionierte Elektrophorese rein erhalten. Es enthielt 45% Kohlenhydrat und 55% Protein. Das Molekulargewicht, bestimmt in der Ultrazentrifuge, beträgt 340000. Das Produkt ist elektrophoretisch einheitlich.
Single‐Crystal SiC Nanowires with a Thin Carbon Coating for Stronger and Tougher Ceramic Composites (2005)

SiC nanowires (NWs) reinforce SiC matrix composites with high efficiency. With the incorporation of ∼ 6 vol.-% randomly oriented single-crystal SiC NWs in the matrices, the fracture toughnesses and flexural strengths of the composites doubled. The composites (see Figure) were fabricated in situ by a new process based on chemical vapor infiltration. Reinforcement efficiency of the NW is affected by the amount of C deposited on the NWs as the NW/matrix interfacial layer.
Easy Synthesis of New Chiral Tridentate Schiff Bases and Their Use as [N,N,O] Ligands for Ni and Pd Complexes − Catalytic Behaviour versus Hydrogenation Reactions (2004)

Abstract The chiral [N,N,O] tridentate unsymmetrical Schiff bases 3−5 (aryl = phenyl, 1‐naphthyl, 2‐naphthyl) were synthesised easily in high purity and good yields. All the organic compounds were characterised by elemental analysis, mass spectrometry, IR, 1 H and 13 C NMR spectroscopy. Palladium( II ) and nickel( II ) Schiff‐base complexes were prepared as air‐stable solids. Because the [N,N,O] ligand is tridentate after deprotonation of the −OH group, the coordination of the metal ion is completely stereospecific and gives rise to only one diastereoisomer. The X‐ray crystal structures of the complexes [Ni( 3 )(OAc)] and [Pd( 4 )(OAc)] were determined. These complexes were shown to be very active catalysts (TOF up to 10 6 h −1 ) for the hydrogenation of olefins and imines under mild conditions. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Retinal ganglion cells recognized by serum autoantibody against gamma-enolase found in glaucoma patients. (2000)

In the current study, serum autoantibody against 50-kDa protein identified as gamma-enolase in 25% of glaucoma patients.
Intercloud federation using via semantic resource federation API and dynamic SDN provisioning (2014)

Intercloud refers to a transparent and voluntary federation of Computing Clouds analogous to the way the Global Internet or Global PSTN/Mobile Telephony works. Individual Service Providers join into a predefined Common Channel Signaling network (Backbone IP Routing protocols in the case of the Internet, the SS7/IN network in the case of the PSTN/Mobile Telephony Network) and exchange infrastructure. Once federation relationships are identified through protocols which transit the Signaling network, a Bearer network relationship is established where the user data is transited. This paper describes the workings of the Intercloud system in terms of the details of the Intercloud Federation API, which transits the signaling network, and how this API is used to dynamically provision a Software Defined Network (SDN) based Virtual Private Cloud (VPC) using Virtual Private networks (VPN), creating the federating bearer network for the transparent federation. The Intercloud Federation API is based on a semantic definition of resources, Service Level Agreements (SLA), and Bearer Network Provisioning Metadata.
Norovirus Attachment and Entry (2019)

Human norovirus is a major human pathogen causing the majority of cases of viral gastroenteritis globally. Viral entry is the first step of the viral life cycle and is a significant determinant of cell tropism, host range, immune interactions, and pathogenesis. Bile salts and histo-blood group antigens are key mediators of norovirus entry; however, the molecular mechanisms by which these molecules promote infection and the identity of a potential human norovirus receptor remain unknown. Recently, there have been several important advances in norovirus entry biology including the identification of CD300lf as the receptor for murine norovirus and of the role of the minor capsid protein VP2 in viral genome release. Here, we will review the current understanding about norovirus attachment and entry and highlight important future directions.
Self-organizing fuzzy logic control for real-time processes (1991)

This study describes the application of the self-organizing fuzzy logic controller (SOFLC) proposed by S. Daley and K.F. Gill (1986) to real-time control of small scale pilot processes, both single-variable and multivariable. The controller can generate and modify control rules to improve its performance. It is concluded that SOFLC is capable of dealing well with a noise-contaminated environment, and for a slow process the computational burden can be accommodated on a low-cost PC. The multivariable process employed has short time constants and necessitates a sampling period of 10-20 msec. A conventional PC is inadequate for performing the SOFLC and associated functions at such a sampling rate. Thus, a transputer-augmented PC system with a single transputer implementation is used for the implementation. The selection of the scaling factors is discussed. >
A Robust Behavior Planning technique for Mobile Robots (2006)

We propose a planning algorithm to automatically generate a robust behavior plan (RBP) with which mobile robots can achieve their task goal from any initial states under dynamically changing environments. For this, task description space (TDS) is formulated, where a redundant task configuration space and simulation model of physical space are employed. Successful task episodes are collected, where algorithm is employed. Interesting TDS state vectors are extracted, where occurrence frequency is used. Clusters of TDS state vectors are found by using state transition tuples and features of state transition tuples. From these operations, characteristics of successfully performed tasks by a simulator are abstracted and generalized. Then, a robust behavior plan is constructed as an ordered tree structure, where nodes of the tree are represented by attentive TDS state vector of each cluster. The validity of our method is tested by real robot's experimentation for a box-pushing-into-a-goal task.
IV immunoglobulin in patients with myasthenia gravis (2007)

This study provides level 1 evidence for the effectiveness of IV immunoglobulin in patients with worsening weakness due to myasthenia gravis.
Optimal Design of Non-Regenerative MIMO Wireless Relays (2007)

Given a multiple-antenna source and a multiple-antenna destination, a multiple-antenna relay between the source and the destination is desirable under useful circumstances. A non-regenerative multiple-antenna relay, also called non-regenerative MIMO (multi-input multi-output) relay, is designed to optimize the capacity between the source and the destination. Without a direct link between the source and the destination, the optimal canonical coordinates of the relay matrix are first established, and the optimal power allocations along these coordinates are then found. The system capacity with the optimal relay matrix is shown to be significantly higher than those with heuristic relay matrices. When a direct link is present, upper and lower bounds of the optimal system capacity are discussed.
Study highlights carers’ health often overlooked in assessments (2009)

The physical health of carers with chronic conditions is harmfully affected by their caring role. Carers reportedly neglect their own clinical or treatment need, or miss meals because of their prevailing caring responsibilities. This longitudinal five-year study from Bangor, North Wales, also reported that although guidelines require that the carer’s own health should be taken into consideration during the carer assessment, only one carer described such an enquiry being made.
UAMDroid: A user authority manager model for the Android platform (2011)

Abstract Smartphones are taking over the task of Personal Digital Assistant and becoming pocket computers due to their fully customizable software and personalization in terms of the personal data stored on them. Thus, how to prevent the private and sensitive information from exposing to outside world is necessary to be taken into account. However, current smartphone operating systems support only a single user mode which is suitable for the phone owner to work with. In this paper, we present a user authority manager model namely UAMDroid for the Android platform that allows phone owner to specify what applications the phone borrowers should be prohibited to access or uninstall, as well as whether extra applications should be allowed to install. We detail our model that extends the existing Android application framework and describe its prototype of implementation. The performance evaluation shows that UAMDroid only produces a minimal impact on the normal usage of smartphones which is tolerable. Our proposal is lightweight and can efficiently secure personal data in multi-user case.
IoT Based Secure Smart City Architecture Using Blockchain (2018)

Standard security protocols are heavy weight interms of memory foot prints which make all the security protocol unfit for budgeted platforms such as Internet of Things (IoT). The blockchain (BC) is a very efficient architecture to preserve five basic cryptographic primitives, such as authenticity, integrity, confidentiality, availability and non-repudiation. Conventional adoption of blockchain in IoT causes significant energy consumption, delay, and computational overhead which are not suitable for various resource-constrained IoT devices. In our submission we change the basic architecture of blockchain and make it more efficient for IoT application. The article proposes an IoT based smart city architecture which adopted the blockchain technology preserving all the cryptographic security issues. The adoption of blockchain causes very minimal overhead on IoT platform. Comparison of all security parameters with existing literature shows that the architecture is reasonably efficient in terms of security
Convenient synthesis of some purine 8,5'-imino cyclonucleosides (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConvenient synthesis of some purine 8,5'-imino cyclonucleosidesTadashi Sasaki, Katsumaro Minamoto, and Hidemi ItohCite this: J. Org. Chem. 1978, 43, 12, 2320–2325Publication Date (Print):June 1, 1978Publication History Published online1 May 2002Published inissue 1 June 1978https://doi.org/10.1021/jo00406a003Request reuse permissionsArticle Views3144Altmetric-Citations56LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (846 KB) Get e-Alertsclose Get e-Alerts