gebhart/patrepeval huggingface dataset:
Surface Roughness Influence on Eddy Current Electrical Conductivity Measurements (2003)

The measurement of eddy current conductivity, in view of its frequency dependent penetration depth, has been suggested as a possible means to allow the nondestructive testing (NDT) of subsurface residual stresses in shot peened specimens. This paper addresses the apparent reduction of the near surface electrical conductivity measured by the eddy current method in the presence of surface roughness. Experimental results are presented on shot peened pure (C11000) copper, in which the effect is particularly strong and readily measurable because of the low penetration depth caused by the very high electric conductivity of the material. Eight shot peened samples between almen intensities 2 and 16 were thermally treated and tested by X-ray diffraction measurements until the residual stress and cold work fully dissipated, leaving only the surface roughness. Eddy current electrical conductivity measurements were carried out on each fully relaxed shot peened copper specimen over a wide frequency range from 1 kHz to 10 MHz. Our results show that surface roughness, acting alone, causes a srong apparent reduction of up to 10 to 20% of the measured electrical conductivity in shot peened copper. These results can be used to estimate the much smaller effect of surface roughness on the testing of shot peened turbine engine materials, which typically have approximately 100 times lower conductivity than pure copper and therefore exhibit 10 times higher penetration depth at the same test frequency. A comparison of the predicted underestimation of the electrical conductivity in the presence of surface roughness to the expected less than 1% conductivity increase due to compressive near surface residual stresses indicates that the described artifact can significantly affect eddy current testing of shot peened turbine engine alloys, such as Ti-6A1-4V or IN100.
HIF, hypoxia and the role of angiogenesis in non-small cell lung cancer (2010)

Angiogenesis is a key mediator of NSCLC progression. Several antiangiogenic strategies are in clinical use and under development. While candidate predictive biomarkers of response to antiangiogenic therapy exist, they await independent and prospective validation.
Electron Transfer at Electrodes through Conjugated “Molecular Wire” Bridges (1999)

Electron-transfer rates and electronic coupling factors for ferrocene groups attached to gold electrodes via oligo(phenylethynyl) “molecular wire” bridges of variable length and structure are reported. Attachment to gold was achieved via thiol groups at the end of the bridge opposite the ferrocene. Bridge structures were designed to promote strong coupling between gold and ferrocene, thereby promoting rapid electron transport over long distances. The effects of bridge length and of substituents on the phenyl rings in the bridge were addressed. Bridges containing between three and six phenylethynyl units were studied, and a “beta” value of 0.36 Å-1 describing the exponential distance dependence of bridge-mediated electron-transfer rates was obtained. The effect on the rates of adding two propoxy groups onto one of the phenyl rings in the bridge was examined and found to be minimal. The standard electron-transfer rate constant of 350 s-1 obtained for the adsorbate with the longest bridge (six phenylethynyl units, corresponding to an electron-transfer distance of approximately 43 Å) corresponds to an electronic coupling factor between ferrocene and gold of approximately 0.7 cm-1. The extrapolated rate constants at very short distances were nearly the same for the conjugated bridge series and for a related monolayer series in which ferrocene groups were linked to gold via aliphatic bridges. The extrapolated rate constants at short distance also agree with a calculated rate constant for the limiting case of adiabatic electron transfer at an electrode.
Glutaredoxins Grx3 and Grx4 regulate nuclear localisation of Aft1 and the oxidative stress response in<i>Saccharomyces cerevisiae</i> (2006)

Grx3 and Grx4, two monothiol glutaredoxins of Saccharomyces cerevisiae, regulate Aft1 nuclear localisation. We provide evidence of a negative regulation of Aft1 activity by Grx3 and Grx4. The Grx domain of both proteins played an important role in Aft1 translocation to the cytoplasm. This function was not, however, dependent on the availability of iron. Here we demonstrate that Grx3, Grx4 and Aft1 interact each other both in vivo and in vitro, which suggests the existence of a functional protein complex. Interestingly, each interaction occurred independently on the third member of the complex. The absence of both Grx3 and Grx4 induced a clear enrichment of G1 cells in asynchronous cultures, a slow growth phenotype, the accumulation of intracellular iron and a constitutive activation of the genes regulated by Aft1. The grx3grx4 double mutant was highly sensitive to the oxidising agents hydrogen peroxide and t-butylhydroperoxide but not to diamide. The phenotypes of the double mutant grx3grx4 characterised in this study were mainly mediated by the Aft1 function, suggesting that grx3grx4 could be a suitable cellular model for studying endogenous oxidative stress induced by deregulation of the iron homeostasis. However, our results also suggest that Grx3 and Grx4 might play additional roles in the oxidative stress response through proteins other than Aft1.
Flexible and Semitransparent Organic Solar Cells (2017)

Abstract Flexible and semitransparent organic solar cells (OSCs) have been regarded as the most promising photovoltaic devices for the application of OSCs in wearable energy resources and building‐integrated photovoltaics. Therefore, the flexible and semitransparent OSCs have developed rapidly in recent years through the synergistic efforts in developing novel flexible bottom or top transparent electrodes, designing and synthesizing high performance photoactive layer and low temperature processed electrode buffer layer materials, and device architecture engineering. To date, the highest power conversion efficiencies have reached over 10% of the flexible OSCs and 7.7% with average visible transmittance of 37% for the semitransparent OSCs. Here, a comprehensive overview of recent research progresses and perspectives on the related materials and devices of the flexible and semitransparent OSCs is provided.
Severity of salpingitis in mice after primary and repeated inoculation with a human strain of Chlamydia trachomatis. (1990)

Groups of inbred female mice of strains CBA or C3H were infected genitally with a pathogenic human strain of Chlamydia trachomatis (N.I.1, serovar F) known to produce salpingitis and infertility in mice. Mice were inoculated under the ovarian bursa or directly into the uterine cavity with chlamydiae (test groups) or with sucrose-phosphate transport medium (control groups) before being challenged with chlamydiae by the same route 12-17 weeks later. Twenty-five pairs of test and control animals were killed from 7 to 77 days after challenge and oviductal inflammatory changes, recovery of organisms, and antibody responses were compared in the two groups. Salpingitis in the mice infected previously (tests groups) was more severe than in the controls in 56% of comparisons, the same in 24% and less severe in 20%. However, despite the increase in the severity of disease, shedding of C. trachomatis from the lower genital tract was less prolonged after rechallenge or did not occur. Salpingitis occurred in spite of the almost certain presence of pre-existing serum antibody, and accelerated and accentuated antibody response in the rechallenged mice. Furthermore, the continued existence of high titres of antibody was not associated with less severe disease. Thus, the results reveal that previous exposure to chlamydiae does not prevent salpingitis and suggest that its severity is influenced by cell-mediated immune mechanisms.
Acceleration at the Edge for Supporting SMEs Security: The FORTIKA Paradigm (2019)

This article presents FORTIKA, an ongoing EU-funded project which is a resilient cyber-security solution that can easily be tailored and adjusted to the versatile and ever changing needs of small and medium-sized enterprises (SMEs). To fulfill its vision, FORTIKA adopts a security-by-design hybrid approach that adequately integrates hardware and software with business needs and behavioral patterns at the individual and organizational levels to introduce an FPGA-powered middleware security layer as an add-on to existing network gateways, orientating small business users to trusted cyber-security services (through FORTIKA's marketplace) packaged in tailored solutions for each enterprise, and further extended to accommodate security intelligence and encourage security-friendly behavioral and organizational changes. Finally, the introduction of a software-defined smart ecosystem in the FORTIKA marketplace provides the feature of a lightweight solution, which offers virtualized security services (with minimum downloading requirements). Users (i.e., SMEs) may utilize a variety of services and share profiling information with the service providers in return for tailored security services aligned with their actual needs. FORTIKA marketplace also functions as a single point of access for the profiling information for each SME. Preliminary evaluation results indicate that users can upload bundles to the marketplace repository in approximately 4 to 5 minutes, download bundles from the FORTIKA marketplace to the gateway in approximately 20 seconds, and deploy them in an average of 4.5 ms.
Corrosion of mild and stainless steel by four tropical <i>Desulfovibrio desulfuricans</i> strains (1981)

The corrosion potential of four tropical Desulfovibrio desulfuricans isolates was determined using a semicontinuous batch culture technique in a 56-day test incubated at 37 degrees C. The corrosion potentials for mild and stainless steel of marine or brackish water isolates (0.55 and 0.0026 mg cm-2 day-1) were observed to be approximately twice those of freshwater isolates (0.23 and 0.0014 mg cm-2 day-1). Under comparable experimental conditions of severe anaerobic corrosion, stainless steel was found to be over 200 times more resistant than mild steel.
Modality-Invariant Image Classification Based on Modality Uniqueness and Dictionary Learning (2016)

We present a unified framework for the image classification of image sets taken under varying modality conditions. Our method is motivated by a key observation that the image feature distribution is simultaneously influenced by the semantic-class and the modality category label, which limits the performance of conventional methods for that task. With this insight, we introduce modality uniqueness as a discriminative weight that divides each modality cluster from all other clusters. By leveraging the modality uniqueness, our framework is formulated as unsupervised modality clustering and classifier learning based on modality-invariant similarity kernel. Specifically, in the assignment step, each training image is first assigned to the most similar cluster according to its modality. In the update step, based on the current cluster hypothesis, the modality uniqueness and the sparse dictionary are updated. These two steps are formulated in an iterative manner. Based on the final clusters, a modality-invariant marginalized kernel is then computed, where the similarities between the reconstructed features of each modality are aggregated across all clusters. Our framework enables the reliable inference of semantic-class category for an image, even across large photometric variations. Experimental results show that our method outperforms conventional methods on various benchmarks, such as landmark identification under severely varying weather conditions, domain-adapting image classification, and RGB and near-infrared image classification.
Investigation of an improved hybrid-excitation flux switching brushless machine for HEV/EV applications (2014)

Hybrid-excited flux-switching (HEFS) machine was proposed by reducing the permanent magnet (PM) length of an original flux-switching permanent magnet (FSPM) machine and introducing a set of field windings into the saved space. In this paper, the open-circuit performance of an original 3-phase 12-stator-slot/10-rotor-pole HEFS machine is analyzed by 2D finite element analysis (FEA), and further validated by experimental measurement. Then an improved topology is proposed to enhance the flux-regulation capability. The improved topology shares identical motor structure with the original one, but has different field current directions in some field slots. Based on FEA, the open-circuit electromagnetic performances of the two HEFS machines are compared with more attention paid to field regulations. It is found that the improved HEFS machine exhibits distinct field excitation functions and significantly better flux-regulation capability than the original one.
GPU acceleration of a production molecular docking code (2009)

Modeling the interactions of biological molecules, or docking, is critical to both understanding basic life processes and to designing new drugs. Here we describe the GPU-based acceleration of a recently developed, complex, production docking code. We show how the various functions can be mapped to the GPU and present numerous optimizations. We find which parts of the problem domain are best suited to the different correlation methods. The GPU-accelerated system achieves a speedup of at least 17.7x with respect to a single core and 6.1x with respect to four cores for all likely problems sizes. This makes it competitive with FPGA-based systems for small molecule docking, and superior for proteinprotein docking.
Radiolabelled leucocytes in human pulmonary disease (2018)

These include advancement of eosinophil imaging, development of monocyte labelling, development of cell labelling with PET tracers and the tracking of lymphocytes.
A Study on Correlation between Landscape Image of Korean Palace and Trees' View Blockage of Buildings around It (2011)

Many Korean palaces such as Deoksu Palace and Kyungbok Palace are located in downtown Seoul. Modern high-rise buildings around the palace have been the background scenery of traditional architecture in it. In this case, such landscapes mixed with traditional images and contemporary images can give a negative impression to visitors watching from inside the palace. In this study, we analysed the correlation between landscape image of Deoksu Palace and trees' view blockage of buildings around it with three independent variables. The first variable is completely blocked view of buildings around the palace by the trees. The second variable is half-blocked view of buildings around the palace by the trees. The third variable is the view of buildings around the palace that is not blocked by the trees. The analysis showed that there were some significant correlations between landscape image of Deoksu Palace and trees' view blockage of buildings around it. It also showed that the view blockage ratio by the trees has positive correlation with improvement of landscape image of the palace.
Vertically oriented cobalt selenide/NiFe layered-double-hydroxide nanosheets supported on exfoliated graphene foil: an efficient 3D electrode for overall water splitting (2015)

A 3D ternary hybrid containing Co<sub>0.85</sub>Se nanosheet-array and NiFe-LDH grown on electrochemically exfoliated graphene was synthesized for highly-efficient overall water-splitting.’
Successful use of pregabalin by the rectal route to treat chronic neuropathic pain in a patient with complete intestinal failure (2015)

Pregabalin is widely used for treatment of neuropathic pain and is only approved for oral use. This is the first reported case of using pregabalin by the rectal route for treatment in a 70-year-old patient with chronic neuropathic pain and complete intestinal failure. Therapies used in an attempt to manage his chronic pain have included a variety of doses and strengths of opioid preparations and cannabinoids, plus topical and alternative therapies. These were not effective, so it was decided to start a trial of pregabalin administered by the rectal route. Serum levels were measured to assess absorption. Within a few weeks of starting the treatment, the patient had improved pain control and appeared more comfortable and calm.
Architectures for adaptive weight calculation on ASIC and FPGA (2003)

We compare two parallel array architectures for adaptive weight calculation based an QR-decomposition by Givens rotations. We present FPGA implementations of both architectures and compare them with an ASIC-based solution. The throughput of the FPGA implementations is of the order 5-20 GigaFLOPS, making FPGA a viable alternative to ASIC implementation in applications where power consumption and volume cost are not critical.
Optimization of condition-based asset management using a predictive health model (2009)

In this paper, a model predictive framework is used to optimize the operation and maintenance actions of power system equipment based on the predicted health sate of this equipment. In particular, this framework is used to predict the health state of transformers based on their usage. The health state of a transformer is hereby given by the hot-spot temperature of the paper insulation of the transformer and is predicted using the planned loading of the transformer. The actual loading of the transformer is subsequently optimized using these predictions. If you want to cite this report, please use the following reference instead: G. Bajracharya, T. Koltunowicz, R.R. Negenborn, Z. Papp, D. Djairam, B. De Schutter, J. J. Smit. Optimization of condition-based asset management using a predictive health model. In Proceedings of the 16th International Symposium on High Voltage Engineering (ISH 2009), Cape Town, South Africa, August 2009.
Quantitative Analysis of Toremifene Metabolites in Biological Specimens Using High-Performance Liquid Chromatography (1990)

Abstract Toremifene is a triphenylethylene derivatiye that is currently undergoing Phase I-III clinical trials for antineoplastic activity. Toremifene has also shown chemosensitizing activity in multidrug resistant cancer cells. In the present study, we developed a modified HPLC assay which allows for separation, and quantification of toremifene metabolites in biological specimens. Plasma samples containing various quantities of toremifene metabolites were spiked with an internal standard (nafoxidine), extracted with 2% butanol in hexane, and irradiated with high intensity ultraviolet light (254 nm). Aliquots of the extracted plasma components were injected onto a C18 reverse phase column and eleuted isocratically with a mobile phase of 7% water and 0.18% triethylamine in methanol. Fluorescence of toremifene metabolites, and internal standard was measured at an excitation wavelength of 266nm. The sensitivity of this assay was approximately 20 ng/mL for each metabolite. Linearity was achieved for all the compounds with correlation coefficients of greater than, 0.99. The assay presented is highly specific, very sensitive, and demonstrates reproducible linearity throughout a wide range of clinically relevant plasma concentrations.
Electrometric titration of insulin. Preparation and properties of iodinated insulin (1936)

THE work to be described in the present paper represents an attempt to obtain accurate data concerning the acid-and base-binding powers of pure insulin by the method of electrometric titration. The experiments have been extended to a study of the physico-chemical and physiological properties of an iodinated product obtained from crystalline insulin by a method which has been used successfully with other proteins [cf. Neuberger, 1934, 2] and which appears to be limited in its effect to substitution of the tyrosine groups.
Inhalation Anesthesiology and Volatile Liquid Anesthetics: Focus on Isoflurane, Desflurane, and Sevoflurane (2005)

Clinical pharmacists rarely are involved in the selection and dosing of anesthetic agents. However, when practicing evidence-based medicine in a cost-conscious health care system, optimizing drug therapy is imperative in all areas. Thus, we provide general information on anesthesiology, including the different types of breathing systems and the components of anesthesia machines. Modern inhalation anesthetics that are predominantly used in clinical practice include one gas--nitrous oxide--and new volatile liquid agents--isoflurane, desflurane, and sevoflurane. Desflurane and sevoflurane are the low-soluble inhalation anesthetics, and they offer some clinical advantages over isoflurane, such as fast induction and faster recovery with long procedures. However, efficient use of isoflurane can match the speed of induction and recovery of the other agents in certain cases. In addition, the patient characteristics, duration and type of procedure, type of breathing system, and efficiency in monitoring must be considered when selecting the most optimal therapy for each patient. Maximizing the clinical advantages of these agents while minimizing the waste of an institution's operating room and pharmacy budget requires an understanding of the characteristics, pharmacokinetics, and pharmacodynamics of these anesthetic agents and the collaborated effort from both the anesthesia and pharmacy departments. An anesthetic agent algorithm is provided as a sample decision-process tree for selecting among isoflurane, desflurane, and sevoflurane.
IIR multiple notch filter design based on allpass filter (1997)

A new technique for IIR multiple notch filter design is proposed. The specification of notch filter is first transformed into that of allpass filter. Then, we develop an effective approach to design this desired allpass filter. The realization of proposed notch filter is equivalent to the realization of an allpass filter. Due to the mirror-image symmetry relation between the numerator and denominator polynomials of allpass filter, the notch filter can be realized by a computationally efficient lattice structure with very low sensitivity. Moreover, some examples are presented to examine the effectiveness of proposed method.
“Authoring Experience” : A Dialogue on the Dancer’s Practice (2013)

In the spring of 2011, I posed a few questions to Chrysa Parkinson, upon reading some of her earlier writings. The discussion between us developed into an email conversation that was revised with the help of Anna Petronella Foultier, resulting in the following text. Cecilia Roos
Excitation of morphology-dependent resonances and van de Hulst’s localization principle (1999)

When a laser beam scatters from a microparticle whose shape deviates from that of a sphere, a number of partial waves of the incident beam couple to a given partial wave of the scattered and interior fields. As a result, partial-wave coupling caused by small surface irregularities of a liquid droplet provides the mechanism for exciting low-radial-order morphology-dependent resonances.
Lexically Constrained Decoding for Sequence Generation Using Grid Beam Search (2017)

We present Grid Beam Search (GBS), an algorithm which extends beam search to allow the inclusion of pre-specified lexical constraints. The algorithm can be used with any model that generates a sequence $ \mathbf{\hat{y}} = \{y_{0}\ldots y_{T}\} $, by maximizing $ p(\mathbf{y} | \mathbf{x}) = \prod\limits_{t}p(y_{t} | \mathbf{x}; \{y_{0} \ldots y_{t-1}\}) $. Lexical constraints take the form of phrases or words that must be present in the output sequence. This is a very general way to incorporate additional knowledge into a model's output without requiring any modification of the model parameters or training data. We demonstrate the feasibility and flexibility of Lexically Constrained Decoding by conducting experiments on Neural Interactive-Predictive Translation, as well as Domain Adaptation for Neural Machine Translation. Experiments show that GBS can provide large improvements in translation quality in interactive scenarios, and that, even without any user input, GBS can be used to achieve significant gains in performance in domain adaptation scenarios.