gebhart/patrepeval huggingface dataset:
A privacy-compliant fingerprint recognition system based on homomorphic encryption and Fingercode templates (2010)

The privacy protection of the biometric data is an important research topic, especially in the case of distributed biometric systems. In this scenario, it is very important to guarantee that biometric data cannot be steeled by anyone, and that the biometric clients are unable to gather any information different from the single user verification/identification. In a biométrie system with high level of privacy compliance, also the server that processes the biométrie matching should not learn anything on the database and it should be impossible for the server to exploit the resulting matching values in order to extract any knowledge about the user presence or behavior. Within this conceptual framework, in this paper we propose a novel complete demonstrator based on a distributed biométrie system that is capable to protect the privacy of the individuals by exploiting cryptosystems. The implemented system computes the matching task in the encrypted domain by exploiting homomorphic encryption and using Fingercode templates. The paper describes the design methodology of the demonstrator and the obtained results. The demonstrator has been fully implemented and tested in real applicative conditions. Experimental results show that this method is feasible in the cases where the privacy of the data is more important than the accuracy of the system and the obtained computational time is satisfactory.
Antioxidant therapy for chronic hepatitis C after failure of interferon: Results of phase II randomized, double-blind placebo controlled clinical trial (2007)

Antioxidant therapy has a mild beneficial effect on the inflammatory response of chronic HCV infection patients who are non-responders to interferon. Combined antiviral and antioxidant therapy may be beneficial for these patients.
New conjunctive reagents. 2-Acetoxymethyl-3-allyltrimethylsilane for methylenecyclopentane annulations catalyzed by palladium(0) (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew conjunctive reagents. 2-Acetoxymethyl-3-allyltrimethylsilane for methylenecyclopentane annulations catalyzed by palladium(0)Barry M. Trost and Dominic M. T. ChanCite this: J. Am. Chem. Soc. 1979, 101, 21, 6429–6432Publication Date (Print):October 1, 1979Publication History Published online1 May 2002Published inissue 1 October 1979https://pubs.acs.org/doi/10.1021/ja00515a046https://doi.org/10.1021/ja00515a046research-articleACS PublicationsRequest reuse permissionsArticle Views2431Altmetric-Citations206LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
A 1-M bit SRAM on SIMOX material (2002)

A 1-M bit SRAM with 0.8 um feature sizes has been successfully fabricated using SIMOX material. The advantages of SOI for low capacitance, latch-up immunity, and reduced collection charge for single events have been long recognized. The demonstration of a 1-M SRAM at 0.8 um is a significant milestone in the evaluation of the technology for fabrication of very large scale integrated circuits.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Efficient LaF_3:Nd^3+-based vacuum-ultraviolet laser at 172 nm (1992)

Vacuum-ultraviolet (VUV) laser radiation at 172 nm has been obtained from a solid-state LaF3:Nd3+-based laser pumped by a pulsed-discharge molecular F2 laser at 157 nm. The maximum slope efficiency of the solid-state laser described in this experiment was 21% (14% conversion efficiency), and the maximum output energy at 172 nm was 0.4 mJ for a nonoptimized optical cavity. This finding introduces serious prospects for realizing versions of active-medium-plus-source tunable VUV laser devices.
Immunization with a Combination of Merozoite Surface Proteins 4/5 and 1 Enhances Protection against Lethal Challenge with<i>Plasmodium yoelii</i> (2002)

It is widely believed that subunit vaccines composed of multiple components will offer greater protection against challenge by malaria, and yet there is little experimental evidence to support this view. We set out to test this proposition in the Plasmodium yoelii challenge system in rodents by comparing the degree of protection conferred by immunization with a mixture of merozoite surface proteins to that conferred by single proteins. We therefore examined a defined protein mixture made of the epidermal growth factor-like domains of P. yoelli merozoite surface protein 1 (MSP1) and MSP4/5, the homologue of P. falciparum MSP4 and MSP5. In the present study we demonstrate that this combination of recombinant proteins dramatically enhances protection against lethal malaria challenge compared to either protein administered alone. Many mice immunized with the MSP4/5 plus MSP1(19) combination did not develop detectable parasitemia after challenge. Combined immunization with MSP1(19) and yMSP4/5, a product characterized by lower protective efficacy, also greatly enhanced protection by reducing peak parasitemias and increasing the numbers of survivors. In some combination trials, levels of antibodies to MSP1(19) were elevated compared to the MSP1(19) alone group; however, improved protection occurred regardless of whether boosting of the anti-MSP1(19) response was observed. Boosting of anti-MSP1(19) did not appear to be due to contaminating endotoxin in the EcMSP4/5 material since enhanced protection was observed in C3H/HeJ mice, which are endotoxin insensitive. Collectively, these experiments show that multiantigen combinations offer enhanced levels of protection against asexual stage infection and suggest that combinations of MSP1, MSP4, and MSP5 should be evaluated further for use in humans.
High-Definition Resistivity Imaging of Low-Resistivity Formations Drilled with Nonconductive Mud Systems for Near-Wellbore Geological and Petrophysical Reservoir Evaluation (2014)

A new wire-line formation resistivity imaging instrument employing a ‘two-electrode’ measurement configuration has been developed for application in low-resistivity formations drilled with non-conductive (oil-based) mud. A detailed explanation of the instrument and measurement principles is provided. Modeled synthetic responses and field examples are shown. The high-spatial resolution of a ‘two-electrode’ arrangement has been well documented for nearly 25 years. The lower formation resistivity limit in oil-based mud boreholes for prior devices often precluded realizing their benefits in many important offshore deep water plays, such as Malaysia, Gulf of Mexico and elsewhere. The new instrument employs multi-frequency impedance measurements to overcome this limitation. The impedance measurements produce two image logs: a real-part impedance image that is calibrated to yield formation resistivity and an imaginary-part impedance image that conveys information about image quality. The instrument employs six individually-articulated pads each containing ten sensor electrodes that provide a 75% surface coverage in an 8½ inch borehole. Typical spatial-resolution is better than one-half-inch vertically and one-eighth inch azimuthally. Pad-to-pad depth off-set is less than 6 inches, assisting to maintain borehole coverage in the presence of common instrument rotation during logging. Field examples from typical logging environments found in offshore Malaysia are presented. Detailed geologic features such as thin-beds, slumping, cross-bedding, faulting and fracturing in low resistivity depositional environments are clearly resolved.
Optimization of IGF-1R SPECT/CT Imaging Using <sup>111</sup>In-Labeled F(ab′)<sub>2</sub> and Fab Fragments of the Monoclonal Antibody R1507 (2012)

The insulin-like growth factor 1 receptor (IGF-1R) is a potential new target for the treatment of breast cancer. Patients with breast cancer lesions that express IGF-1R may benefit from treatment with anti-IGF-1R antibodies. IGF-1R expression can be visualized using radiolabeled R1507, a monoclonal antibody directed against IGF-1R. However, antibodies clear slowly from the circulation, resulting in low tumor-to-background ratios early after injection. Therefore, we aimed to accelerate targeting of IGF-1R using radiolabeled R1507 F(ab')2 and Fab fragments. In vitro, immunoreactivity, binding affinity and internalization of R1507 IgG, F(ab')2 and Fab were determined using the triple negative IGF-1R-expressing breast cancer cell line SUM149. In vivo, pharmacokinetics of (111)In-labeled R1507 IgG, F(ab')2 and Fab were studied in mice bearing subcutaneous SUM149 xenografts. SPECT/CT images were acquired and the biodistribution was measured ex vivo. The in vitro binding characteristics of radiolabeled R1507 IgG and F(ab')2 were comparable, whereas the affinity of Fab fragments was significantly lower (Kd: 0.6 nM, 0.7 nM and 3.0 nM for R1507 IgG, F(ab')2 and Fab, respectively). Biodistribution studies showed that the maximum tumor uptake of (111)In-R1507 IgG, F(ab')2 and Fab was 31.8% ID/g (72 h p.i.), 10.0% ID/g (6 h p.i.), and 1.8% ID/g (1 h p.i.), respectively. However, maximal tumor-to-blood ratios for F(ab')2 (24 h p.i.: 7.5) were more than twice as high as those obtained with R1507 (72 h p.i.: 2.8) and Fab (6 h p.i.: 2.8). Injection of an excess of unlabeled R1507 significantly reduced tumor uptake, suggesting that the uptake of R1507 IgG and F(ab')2 was specific for IGF-1R, while the major fraction of the tumor uptake of Fab was nonspecific. IGF-1R-expressing xenografts were visualized with (111)In-F(ab')2 SPECT/CT as early as 6 h p.i., while with R1507 IgG, the tumor could be visualized after 24 h. No specific targeting was observed with (111)In-Fab. (111)In-F(ab')2 fragments showed improved targeting of IGF-1R expressing tumors. Tumor-to-blood ratios were twice as high as those obtained with (111)In-R1507, and adequate tumor targeting on SPECT/CT images was observed as early as 6 h p.i. For individualization and optimization of IGF-1R targeted therapy, (111)In-F(ab')2 may be the tracer of choice.
Diagnostic significance of adenosine deaminase, uric acid and C-reactive protein levels in patients of head and neck carcinoma. (2011)

Thus, estimation of adenosine deaminase, uric acid, and C-reactive protein can help in making the diagnosis and assessing the severity of disease in patients of head and neck carcinoma.
Random mutagenesis of Luciola mingrelica firefly luciferase. Mutant enzymes with bioluminescence spectra showing low pH sensitivity (2008)

Most firefly luciferases demonstrate a strong pH-dependence of bioluminescence spectra. Gene region encoding first 225 residues of Luciola mingrelica luciferase was subjected to random mutagenesis, and four mutants with altered pH-sensitivity of bioluminescence spectra were isolated. F16L substitution showed distinctly lower pH-dependence of bioluminescence spectra, and Y35N,H and F16L/A40S substitutions resulted in the enzymes with bioluminescence spectra virtually independent from pH in the range of 6.0-7.8. The structural explanation is proposed for the effect of mutations on pH-sensitivity of bioluminescence spectra.
The dynamical behavior of a single-mode optical fiber strain gage (1982)

A comparison is reported between the dynamical response of a single-mode fiber optic and resistive strain gages in the frequency range 25-250 Hz. The integral phase change of the laser light propagation into the vibrating fiber optic is evaluated. A mechanical system was designed to exactly delimitate the part of the optical fiber which is subjected to vibration. The frequency spectrum of the phase change signal and the resistive strain gage signal show equivalent behavior. This result is in good agreement with the theoretically expected values and confirms the validity of the analysis performed.
Member based separations and counter current multicolumn systems for decolorization, ion exchange and ion exclusion : Emerging technologies for the sugar industry (1997)

Competitive pressures from the sugar beet and corn sweetener industries, the rising cost of solid and liquid waste disposal and other factors are forcing the US sugarcane and refining industries to consider technologies developed first in other industries, but easily adaptable to the sugar industry. Most notably, applications of polymeric and particularly, ceramic membranes, and benefits from introducing counter current continuous systems for decolorization, ion exchange and chromatography separations, hold the promise of a virtual revolution for the industry. This review provides a brief overview of some of the current and anticipated applications, aswell as examples of representative test results from the author's lab.
A Grid Computing Approach to Subtraction Radiography (2006)

Digital subtraction is a common technique used in radiographic studies of periapical lesions and other dental disorders for which the treatment must be evaluated over time. This paper presents a fast and reliable parallel image registration method for subtracting two digitized radiographs where an unpredicted mismatch is present. An optimal affine transformation is found using an adaptive genetic algorithm (GA) as the optimization strategy and a correlation ratio as the similarity measure. The parallel GA implemented takes advantage of the CPU idle cycles of a computational grid, resulting in an application that exploits an existent infrastructure and with a computational time of about twenty seconds when processing pairs of standard intra-oral radiographs.
INTERCELLULAR COMMUNICATION IN RAPIDLY PROLIFERATING AND DIFFERENTIATED C6 GLIOMA CELLS IN CULTURE (1997)

Glial cells in the brain are known to provide structural and functional supports to neurons. To sustain such a supportive role, they have developed cell-to-cell communicating gap junctional channels. The authors studied the effect of dbcAMP on gap junctional channels mediated communication in C6 cells, a rat glioma cell line. Quantitative assessment of coupled cells under microscope after microinjection of a fluorescent dye was taken as a measure of junctional permeability. An enhanced coupling between cells was observed following dbcAMP treatment and this elevated coupling was found to be dependent on the duration of exposure of cells to dbcAMP. The studies have focused on a subtle shift in the spatial organization of the functional channels to the processes of dbcAMP induced differentiated cells from the cell cytoplasms and membranes of dbcAMP untreated cells. Immunofluorescence study with affinity purified antibody against gap junction further confirmed the spatial distribution of gap junctional protein(s) in the processes and also showed an increase in the density of the protein at the intercellular spaces in dbcAMP induced differentiated C6 glioma cells.
Optoelectronic delay-time controller for laser pulses (2000)

A dc-voltage-controlled optoelectronic delay line for continuous tuning of the relative delay time of an optical pulse train generated from a gain-switched laser diode is demonstrated. A maximum tunable range delay time of 3.9 ns ( approximately 2 periods) for optical pulses at a 500-MHz repetition rate is reported, which corresponds to a phase shift of as much as 4pi. The tuning responsivity and resolution of the current apparatus are 0.54 ps/mV and <0.2 ps, respectively. The measured timing fluctuation and long-term drift at any delay time are 0.13 ps and 20 fs/min, respectively. This scheme further permits the simultaneous phase tracking of the laser pulse train to unknown signals generated from the device under test.
Expert System Knowledge Management for Laser Drilling in the Oil and Gas Industry (2006)

The main drilling technique in the oil and gas industry has been rotary. Nevertheless, during the last decade, laser drilling has been investigated. Intensive research work has examined the soundness of this new drilling technique and its profitability. The laser drilling literature has confirmed that this novel technique performs better and faster than the conventional rotary drilling technique. Since the drilling time is reduced, the drilling costs are decreased, and the project profitability is increased. Furthermore, laser drilling eradicates the problem of contaminated water, soil, and rocks since water is used instead of toxic muds while drilling. This paper introduces the knowledge management process for an expert system that is the laser drilling system optimizer (LDSO). Then the development stages are described. The LDSO is an innovation since it is the first expert system developed for laser drilling in the oil and gas industry. It is a knowledge-based optimization system
Purification and characterization of a thermostable glucoamylase from the thermophilic fungus <i>Thermomyces lanuginosus</i> (1981)

Glucoamylase (1,4-alpha-D-glucan glucohydrolase, EC 3.2.1.3) was purified from the culture filtrates of the thermophilic fungus Thermomyces lanuginosus and was established to be homogeneous by a number of criteria. The enzyme was a glycoprotein with an average molecular weight of about 57 000 and a carbohydrate content of 10-12%. The enzyme hydrolysed successive glucose residues from the non-reducing ends of the starch molecule. It did not exhibit any glucosyltransferase activity. The enzyme appeared to hydrolyse maltotriose by the multi-chain mechanism. The enzyme was unable to hydrolyse 1,6-alpha-D-glucosidic linkages of isomaltose and dextran. It was optimally active at 70 degrees C. The enzyme exhibited increase in the Vmax. and decreased in Km values with increasing chain length of the substrate molecule. The enzyme was inhibited by the substrate analogue D-glucono-delta-lactone in a non-competitive manner. The enzyme inhibited remarkable resistance towards chemical and thermal denaturation.
Quadruplex Video-Tape Editing — An Introduction (1970)

Originally the video-tape recorder served as a replacement for television film recordings (kinescopes), which, in the case of live telecasts, provided in the more western time zones program material that was too little and too late. Its use as a studio production tool was not seriously considered until after it had been widely accepted for delayed-program broadcasting.
Real-time rectilinear 3-D ultrasound using receive mode multiplexing (2004)

In previous work, we developed two generations of a real-time rectilinear volumetric scanner operating at 5 MHz for abdominal, breast, or vascular imaging using a Mills cross two-dimensional (2-D) array and a rectilinear periodic 2-D array. To improve spatial resolution performance and sensitivity, we developed a new design using 4:1 receive mode multiplexing. With 4:1 multiplexing, the new 65,000 element 2-D array has 4 x 256 = 1024 receivers so that 256 receivers can be used on any image line. The two major benefits of using receive mode multiplexing are an increase in receive sensitivity due to a greater number of receive elements, and a decrease in grating lobe and clutter levels due to increased receive element density. Theoretical simulations and analysis show an increase of about 13 dB in sensitivity compared to our previous work. With these encouraging results, a new 65,000 element 5-MHz, 2-D array having 1024 receivers and 169 transmitters was prototyped. In addition, the multiplexer and control circuitry were designed, built, and interfaced with both the transducer and volumetric scanner. Images of tissue-mimicking phantoms and in vivo targets were obtained. Using a spherical cyst phantom, experimental results showed a +12 dB improvement in signal-to-noise ratio and a +6 dB improvement in contrast compared to our previous work.
Changes in burn patient care. (1997)

Little has changed in the care of patients with burns for many years but nurses are now becoming involved in the introduction of innovative treatments. This article introduces relevant information about two of these products; cerium nitrate-sliver sulphadiazine (Flammacerium) and Integra, a new form of 'artificial skin'.
Exchange flow through an opening (2002)

This paper presents a theoretical and experimental study of the exchange of fluids of different densities through an opening. Three types of openings are examined: a bottom opening (the opening is at the bottom of a gate), a middle opening (in the middle) and a window opening (the opening is in the middle but does not extend across the width). Simultaneous measurements of velocity field and interface position were obtained using flow visualization and image processing techniques. Experimental results confirm the predictions of the internal hydraulic theory that there are two internal hydraulic controls in the flow through bottom openings, but one control in the middle and window opening experiments. The neglect of non-hydrostatic forces and interfacial mixing in the theory, however, results in a significant underestimate of the exchange rate by more than 50 % in the middle and window opening experiments. The fluctuations in the interface position were caused by Kelvin-Helmholtz instabilities as well as basin-scale internal seiche, and the transition of internally supercritical flow to subcritical flow was caused by the mixing generated by these instabilities.
40. Aspects of stereochemistry. Part XI. Epoxide formation in the cyclohexene and bicycloheptene series (1959)

H. B. Henbest and B. Nicholls, J. Chem. Soc., 1959, 221 DOI: 10.1039/JR9590000221
New agents for the treatment of systemic fungal infections – current status (2002)

Systemic antifungal chemotherapy is enjoying its most dynamic era. More antifungal agents are under development than ever before, including agents in entirely new classes. Major goals of current investigations are to identify compounds with a wide spectrum of activity, minimal toxicity and a high degree of target specificity. The antifungal drugs in development include new azoles {voriconazole, posaconazole (formerly SCH-56592), ravuconazole (formerly BMS-207147)}, lipid formulations of amphotericin B, a lipid formulation of nystatin, echinocandins {anidulafungin (formerly, LY-303366, VER-002), caspofungin (formerly MK-991), micafungin (formerly FK-463)}, antifungal peptides other than echinocandins, and sordarin derivatives. This discussion reviews the currently available antifungal agents and summarises the developmental issues that surround these new systemic antifungal drugs.
Purification of Intrinsic Factor. (1958)

A highly purified intrinsic factor preparation (RAS fraction) was prepared in quantity from fresh hog duodenum by saline extraction, pH adjustment and ammonium sulfate precipitation. This fraction was active in pernicious anemia patients in relapse at daily oral dose of 5 mg. Ultracentrifugal separation could not completely separate the components of RAS fraction. RAS fraction was further purified on a DEAE-cellulose ion exchanger to give a fraction which was active in urinary excretion test at a dose of 3 mg. equivalent to a daily oral dose of 1 mg in pernicious anemia patients in relapse. Rechromatography of this active fraction resulted in no further increase in potency. Ultracentrifugal studies of the most active fraction obtained from rechromatography showed essentially 3 peaks with sedimentation constants of 1.0 S, 2.8 S and 11 S.