gebhart/patrepeval huggingface dataset:
Purification and characterization of the acid-labile subunit of rat serum insulin-like growth factor binding protein complex (1994)

Circulating insulin-like growth factor (IGF) binding protein-3 (IGFBP-3), when occupied by IGF-I or IGF-II, combines with an acid-labile glycoprotein subunit (ALS) to form a high molecular weight complex. In this study, ALS from rat serum has been purified and its properties investigated. Purification involved ion-exchange chromatography, and affinity chromatography on an IGF-I-IGFBP-3 column, yielding almost 1 mg ALS from 100 ml serum. Amino-terminal sequencing confirmed the prediction from previous complementary DNA analysis but indicated that the protein may circulate in a truncated form. Rat ALS was almost as potent as human ALS in binding to human IGF-I-IGFBP-3 complex (association constant, 2.3 nM-1). A sensitive RIA was developed, with high specificity for rodent ALS. Serum ALS rose from 3 micrograms/ml in 2-day-old rats to more than 40 micrograms/ml at 10 weeks, with no sex difference. GH-deficient rats showed 60-75% lower values than controls. This study shows rat ALS to have similar binding properties, and age and GH dependence, to human ALS. The new RIA will facilitate studies of IGF and IGFBP regulation in the rat.
On Tasman Shores - Guy & Joe Lynch in Australasia (2014)

The Tasman Sea, precisely defined by oceanographers, remains inchoate as a cultural area. It has, as it were, drifted in and out of consciousness over the two and a half centuries of European presence here; and remains an almost unknown quantity to prehistory. Its peak contact period was probably the sixty odd years between the discovery of gold in Victoria and the outbreak of the Great War; when the West Coasts of both New Zealand’s main islands, and the South East Coast of Australia, were twin shores of a land that shared an economy, a politics, a literature and a popular culture: much of which is reflected in the pages of The Bulletin from 1880s until 1914. There was, too, a kind of hangover of the pre-war era and of the ANZAC experience into the 1920s; but after that the notional country sank again beneath the waves. This paper attempts recovery of fragments of that lost zone from a prospective standpoint: beginning the restoration of a Weltanschauung which, while often occluded, has never really gone away. It will be undertaken by focussing upon the story of the Melbourne born Lynch brothers and their cohort: Guy and Joe Lynch, George Finey, Cecil ‘Unk’ White and Noel Cook, all of whom migrated from Auckland to Sydney after World War One and worked in the 1920s  as artists, caricaturists and cartoonists on various newspapers and magazines. Joe was sculpted twice in stone by elder brother Guy; as a soldier standing on a plinth in the war memorial at Devonport, Auckland; and, controversially, as a faun in Sydney’s Botanic Gardens. Joe Lynch fell, or jumped, from a ferry one night and drowned in Sydney harbour; and thereby became the inspiration for Kenneth Slessor’s great elegy, Five Bells.
Reduction of Injection Voltage in Signal Injection Sensorless Drives Using a Capacitor-Integrated Inverter (2016)

In signal injection sensorless drives, the injection voltage cannot be reduced under a certain value. The lower limit of the injection voltage is mainly enforced by the inverter nonlinearity that causes distortion of the injection voltage and degradation of the position estimation performance. After analyzing the inverter nonlinearity during the voltage injection, it is revealed that parasitic capacitances of insulated-gate bipolar transistors have positive effects on inverter output linearity and sensorless control. Based on this analysis, this paper proposes a method to reduce the injection voltage by connecting additional capacitors to the output terminals of the inverter. Simulation and experimental results are provided to verify the effectiveness of the proposed idea. In the experiments, using the capacitor-integrated inverter, it is shown that the injection voltage can be reduced by more than half without degrading the position estimation performance.
Acoustic backscattering from ultrasonically tissuelike media (1982)

The acoustic backscattering coefficients of a tissue-mimicking (TM) material have been measured using a modified Sigelmann-Reid technique in order to assess the similarity of its acoustic properties to those of soft tissues. A simple reference scatter material was used to probe the strengths and the limitations of the measurement technique. Backscatter coefficients measured from the TM material exhibit a frequency dependence of the form fm in the range 1.0-8.0 MHz where 3.5 less than or equal to m less than or equal to 3.8. The backscatter coefficient is also found to be approximately proportional to the particle concentration in the TM material up to concentrations that yield an attenuation coefficient of 0.9 db/cm/MHz. Comparisons of backscatter coefficients measured from the TM material are made with published values for liver, myocardium, and blood.
A Prometheus Head-up Display Demonstrator Vehicle (2005)

The purpose of this paper is to describe the thoughts behind defining developing and evaluating a Head-Up Display (HUD) car intended for use within the Prometheus program. The goals behind the project are to: demonstrate HUD technology, demonstrate future traffic information content, and evaluate potential advantages to the driver.
Catalyzed chain transfer to monomer in free radical polymerization (1981)

Abstract The kinetics and the molecular weight distribution in the radical polymerization of methyl methacrylate in the presence of a cobalt complex of hematoporphyrin tetramethyl ether is investigated. The whole complex of experimental data indicates the new kinetic phenomenon—catalyzed chain transfer to monomer. The possible mechanism of the chain transfer and the chain transfer agent regeneration acts is suggested.
Syntheses and Structures of a Macrocyclic β-Diketimine and Its Zinc and Copper Complexes (2004)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTSyntheses and Structures of a Macrocyclic β-Diketimine and Its Zinc and Copper ComplexesSu Yeon Lee, Sung Jae Na, Heon Yong Kwon, Bun Yeoul Lee, and Sang Ook KangView Author Information Department of Molecular Science and Technology, Ajou University, Suwon 443-749 Korea, and Department of Chemistry, Korea University, 208 Seochang, Chochiwon, Chung-nam, 339-700, Korea Cite this: Organometallics 2004, 23, 23, 5382–5385Publication Date (Web):October 15, 2004Publication History Received10 July 2004Published online15 October 2004Published inissue 1 November 2004https://pubs.acs.org/doi/10.1021/om049483whttps://doi.org/10.1021/om049483wrapid-communicationACS PublicationsCopyright © 2004 American Chemical SocietyRequest reuse permissionsArticle Views835Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Aromatic compounds,Crystal structure,Hydrocarbons,Metals,Zinc Get e-Alerts
Screening for Bacteriuria With a Test Paper for Glucose (1968)

A glucose-specific test paper which is sufficiently sensitive to react with the small amounts of glucose present in urine from normal persons in the fasting state can be used to discriminate between urine samples containing more than and those containing less than 1 to 1.5 mg of glucose per 100 ml of urine. This provides a screening method for significant bacteriuria in an apparently healthy population since urine samples, obtained under standardized conditions from subjects in the fasting state with such bacteriuria, contain either very little or no glucose.
Discriminating congestion losses from wireless losses using inter-arrival times at the receiver (2003)

We present a simple scheme which enables a TCP receiver to distinguish congestion losses from corruption losses. The scheme works in the case where the last hop to the receiver is a wireless link and has the smallest bandwidth among all links on the connection path. We added our mechanism to TCP-Reno to evaluate the performance improvement. We compared our scheme against Ideal TCP-Reno which is TCP-Reno that can perfectly (but artificially) distinguish between congestion losses and wireless transmission losses. Under favourable conditions, our scheme performs similar to Ideal TCP-Reno and can lead to significant throughput improvement.
Modulation of in Vivo Antibody Responses by Cholera Toxin (1975)

Treatment of mice with an exotoxin (0.01 mug to 1.0 mug) purified from Vibrio cholerae culture filtrates markedly influenced the immune response to sheep erythrocytes (SRBC) and the Escherichia coli lipopolysaccharide (LPS). Simultaneous administration of the toxin (CT) with antigen resulted in a delayed appearance of antibody plaque-forming cells (PFC) during the first few days after immunization, followed by a marked enhancement of both IgM and IgG PFC. The secondary immune response to SRBC was also similarly affected when CT was given together with a second inoculation of SRBC; i.e., a delay in appearance of hemolytic PFC followed by a markedly enhanced IgM and IgG PFC response. Treatment of mice with cholera toxin 1 to 3 days before SRBC or LPS was immunosuppressive. The effect of CT on the level of splenic cyclic AMP appeared related to the effects on antibody formation.
Low-voltage operational amplifier in 0.12 μm digital CMOS technology (2004)

A fully differential low-power operational amplifier in 0.12 μm digital CMOS technology achieving a differential gain of 80 dB is presented. A transit frequency of 20.5 MHz at ±0.7 V supply and with a load of 10 pF has been measured. Owing to an innovative bulk controller for the input transistors, the common-mode input range is larger than ±0.2 V. The operational amplifier can be used down to a supply voltage of ±0.4 V with a differential gain of 63.5 dB.
LPS alters the immuno-phenotype of glioma and glioma stem-like cells and induces in vivo antitumor immunity via TLR4 (2017)

LPS pretreatment promotes the recognition and eradication of tumor GSCs in vivo when the immune function of the tumor-bearing host is intact. In addition, our data indicate a complex relationship between bacterial infection and glioma prognosis.
Biophysical Characterization of Met-G-CSF: Effects of Different Site-Specific Mono-Pegylations on Protein Stability and Aggregation (2012)

The limited stability of proteins in vitro and in vivo reduces their conversion into effective biopharmaceuticals. To overcome this problem several strategies can be exploited, as the conjugation of the protein of interest with polyethylene glycol, in most cases, improves its stability and pharmacokinetics. In this work, we report a biophysical characterization of the non-pegylated and of two different site-specific mono-pegylated forms of recombinant human methionyl-granulocyte colony stimulating factor (Met-G-CSF), a protein used in chemotherapy and bone marrow transplantation. In particular, we found that the two mono-pegylations of Met-G-CSF at the N-terminal methionine and at glutamine 135 increase the protein thermal stability, reduce the aggregation propensity, preventing also protein precipitation, as revealed by circular dichroism (CD), Fourier transform infrared (FTIR), intrinsic fluorescence spectroscopies and dynamic light scattering (DLS). Interestingly, the two pegylation strategies were found to drastically reduce the polydispersity of Met-G-CSF, when incubated under conditions favouring protein aggregation, as indicated by DLS measurements. Our in vitro results are in agreement with preclinical studies, underlining that preliminary biophysical analyses, performed in the early stages of the development of new biopharmaceutical variants, might offer a useful tool for the identification of protein variants with improved therapeutic values.
C<scp>ube</scp>C<scp>over</scp>– Parameterization of 3D Volumes (2011)

Abstract Despite the success of quad‐based 2D surface parameterization methods, effective parameterization algorithms for 3D volumes with cubes, i.e. hexahedral elements, are still missing. C ube C over is a first approach for generating a hexahedral tessellation of a given volume with boundary aligned cubes which are guided by a frame field. The input of C ube C over is a tetrahedral volume mesh. First, a frame field is designed with manual input from the designer. It guides the interior and boundary layout of the parameterization. Then, the parameterization and the hexahedral mesh are computed so as to align with the given frame field. C ube C over has similarities to the Q uad C over algorithm and extends it from 2D surfaces to 3D volumes. The paper also provides theoretical results for 3D hexahedral parameterizations and analyses topological properties of the appropriate function space.
NAVAL REACTORS PHYSICS HANDBOOK. VOLUME I. SELECTED BASIC TECHNIQUES (1964)

The purpose of this work is to present the most pertinent parts of the body of physics knowledge which has been built up in the course of the Naval and Shippingport (PWR) Reactor Programs, with the aim of providing a background of understanding for those interested in nuclear core design. Volume 1 of this handbook was planned to bring together topics in the basic theoretical and experimental material which are of especially wide interest, including those common to both thermal and intermediate neutron energy reactor types. The physics design of light water-moderated and -cooled reactors is covered in Volume 2 (classified), and that of intermediate neutron-energy power reactors in Volume 3. The emphasis in Volume 1 is thus on light water reactor systems, and as many recent advances in reactor physics of the Naval and Shippingport Reactor Programs as possible have been included.
Critical Stress of Thin-Walled Cylinders in Axial Compression (1947)

Empirical design curves are presented for the critical stress of thin-walled cylinders loaded in axial compression. These curves are plotted in terms of nondimensional parameters of small-deflection theory and are compared with theoretical curves derived for the buckling of cylinders with simply supported and clamped edges. An empirical equation is given for the buckling of cylinders having a length-radius ratio greater than about 0.75. The test data obtained from various sources follow the general trend of the theoretical curve for cylinders with clamped edges, agreeing closely with the theory in the case of short cylinders, but falling considerably below the theoretical results for long cylinders. The discrepancy in the case of long cylinders increases with increasing values of the ratio of radius to wall thickness. Plotting curves for different values of this ratio reduces the scatter in the test data and a certain degree of correlation with theory is achieved. Advantage is taken of this correlation to obtain estimated design curves for cylinders with simply supported edges, for which little experimental information is available. (author)
Laser-Induced Shock Wave Ureteral Lithotripsy Using Q-Switched Nd:YAG Laser (1990)

Laser-induced shock wave generation with a high-intensity Q-switched Nd:YAG laser depends on a laser-induced breakdown in a liquid with formation of an oscillating plasma bubble and cavitational effects. No thermal lesions in porcine urothelium so treated could be found. A new multifunctional laser for shock wave creation (20-nsec pulse duration) for urinary calculi and a free-running mode with millisecond pulses for biliary stones and coagulation of tissue has been developed for use with 320-, 400-, and 600-μm quartz fibers. In 118 patients with 120 calculi treated with laser-induced shock wave lithotripsy (LISL), complete fragmentation of 114 stones was obtained. In the remaining six calculi, laser disintegration was too slow. The efficacy of LISL can be augmented with highly dilute metallic solutions (iron-Ill dextran or magnesium chloride) by a self-focusing effect of the laser beam. With small (320-400 μm) quartz fibers, however, these solutions are not necessary for destruction of hard stones, as the laser focus is minimized.
Attention deficit hyperactivity disorder and Tourette syndrome (2002)

Attention-deficit hyperactivity disorder (ADHD) and tics/Tourette syndrome (TS) are common developmental disorders. Stimulants are the mainstay of treatment for ADHD with approximately 85% of children improving appreciably. However, questions have been raised about their use because of reports describing the appearance or exacerbation of tics/TS in children treated with stimulants for ADHD.1,2⇓ Persisting caveats (even in the current Physician’s Desk Reference ) against the use of stimulants in children with tics/ TS, a family history of tics/TS, or those developing tics while on stimulants have proved extremely problematic in treatment planning. Tics/TS are common in children with ADHD (occurring in as many as 50%),1,3⇓ and ADHD is even more common in children with tics/TS (occurring in up to 90%).4 Several recent stimulant vs placebo-controlled crossover studies in children with ADHD and tics/TS and a few prospective natural history studies of children with tics/TS and children who developed tics during stimulant treatment have not shown a significant or unacceptable increase in tics on stimulant treatment.1-3,5,6⇓⇓⇓⇓ Increases in tics …
Note: Ferrule-top atomic force microscope. II. Imaging in tapping mode and at low temperature (2011)

In a recent paper [D.Chavan et al., Rev. Sci. Instrum. 81, 123702 (2010)] we have demonstrated that ferrule-top cantilevers, obtained by carving the end of a ferruled fiber, can be used for contact mode atomic force microscopy in ambient conditions. Here we show that those probes can provide tapping mode images at both room and cryogenic temperatures (12 K).
Localized surface plasmon resonance based label-free optical biosensor for monitoring peptide nucleic acid-DNA hybridization (2005)

In recent years, label-free biosensors not requiring external modifications have been receiving intense attention. A label-free optical sensor, which retains many of the desirable features of conventional Surface Plasmon Resonance (SPR) reflectometry, namely, the ability to monitor the kinetics of biomolecular interactions in real-time without a label has been developed with several important advantages: the sensor is easy to fabricate, and simple to implement, requiring only an UV-visible spectrophotometer or a flatbed scanner. Importantly, the sensor can be easily multiplexed to enable high-throughput screening of biomolecular interactions in an array-based format. In this research, the development of a label-free optical biosensor based on localized surface plasmon resonance (LSPR) using gold-capped nanoparticle layer substrate is described. This optical monitoring method promises to offer a massively parallel detection capability in a highly miniaturized package. The two-dimensional nanoparticle layer was formed by the surface modified silica nanoparticles. The optical properties of gold-capped nanoparticle layer substrate were characterized through transmission measurements. In this research, monitoring the Peptide nucleic acid (PNA)-DNA hybridization and single-base mismatch detection using this gold-capped nanoparticle layer substrate was carried out.
Electrical and optical properties of amorphous silicon carbide, silicon nitride and germanium carbide prepared by the glow discharge technique (1977)

Abstract Amorphous specimens of silicon carbide, silicon nitride and germanium carbide have been prepared by decomposition of suitable gaseous mixtures in a r.f. glow discharge. Substrates were held at a temperature T d between 400 and 800 K during deposition. In all three of the above materials the results of optical absorption and of d.c. conductivity measurements show a systematic variation with T d and with the volume ratio of the gases used. Electron microprobe results on silicon carbide specimens indicate that a wide range of film compositions can be prepared. The optical gap has a pronounced maximum at the composition Si00–32C0–68 where it is 2·8 eV for a sample deposited at T d = 500 K, but shifts to lower energies with increasing T d. The conductivity above about 400 K has a single activation energy approximately equal to half the optical gap and extended state conduction predominates if the silicon content exceeds 32%. If the latter is reduced, hopping transport takes over and it is suggested that the excess carbon in the network tends to bond in three-fold graphitic coordination. Absence of any obvious feature in the electronic properties at the stoichiometric composition SiC implies that there is little tendency towards compound formation in the glow discharge films. The present results are discussed in relation to measurements on specimens prepared by different methods.
Object detection via boundary structure segmentation (2010)

We address the problem of object detection and segmentation using holistic properties of object shape. Global shape representations are highly susceptible to clutter inevitably present in realistic images, and can be robustly recognized only using a precise segmentation of the object. To this end, we propose a figure/ground segmentation method for extraction of image regions that resemble the global properties of a model boundary structure and are perceptually salient. Our shape representation, called the chordiogram, is based on geometric relationships of object boundary edges, while the perceptual saliency cues we use favor coherent regions distinct from the background. We formulate the segmentation problem as an integer quadratic program and use a semidefinite programming relaxation to solve it. Obtained solutions provide the segmentation of an object as well as a detection score used for object recognition. Our single-step approach improves over state of the art methods on several object detection and segmentation benchmarks.