gebhart/patrepeval huggingface dataset:
An information retrieval system for software components (1988)

This paper describes an information retrieval system which is specifically designed to be used for storing and retrieving information about software components. Rather than use a retrieval mechanism which is simply based on keyword descriptions, the authors have made use of developments in natural language research to represent component information in a form which encodes semantics as well as syntax. The authors call this the component descriptor frame. The paper describes the basic ideas which underlie the system and describes how they can be used for component information retrieval. An example of the system in use is presented. The version of the system described here has been fully implemented using Prolog and is now being developed as part of a more general re-use support system.
Method for Obtaining Fixed Pulse Pattern Suitable for Harmonic Regulation in Large-Capacity PWM Rectifier Systems (2011)

This study examines a method for obtaining a fixed pulse pattern for a neutral-point-clamped PWM rectifier; the method involves the consideration of harmonic regulations. In the PWM rectifier system, a neutral-point-clamped PWM rectifier is connected to the secondary winding of a transformer connected to the grid, and the current is controlled by varying only the phase difference between the fixed pulse pattern and the power source. Therefore, it is possible to use a pulse pattern with reduced harmonics. Two typical types of harmonic regulations were selected. The harmonic regulations described in Harmonic Guidelines and IEEE-519 for high-capacity PWM rectifiers were considered in the above-mentioned method for obtaining the fixed pulse pattern. The fixed pulse pattern was obtained so as to minimize the ratio of the harmonic current content to the regulation values for each harmonic order. For evaluating the effectiveness of the proposed method, the pattern obtained was compared with the patterns obtained by using two other methods—cancellation of low-order harmonics and THD minimization.
β-Dystroglycan as a Target for MMP-9, in Response to Enhanced Neuronal Activity (2007)

Matrix metalloproteinase-9 has recently emerged as an important molecule in control of extracellular proteolysis in the synaptic plasticity. However, no synaptic targets for its enzymatic activity had been identified before. In this report, we show that beta-dystroglycan comprises such a neuronal activity-driven target for matrix metalloproteinase-9. This notion is based on the following observations. (i) Recombinant, autoactivating matrix metalloproteinase-9 produces limited proteolytic cleavage of beta-dystroglycan. (ii) In neuronal cultures, beta-dystroglycan proteolysis occurs in response to stimulation with either glutamate or bicuculline and is blocked by tissue inhibitor of metalloproteinases-1, a metalloproteinase inhibitor. (iii) Beta-dystroglycan degradation is also observed in the hippocampus in vivo in response to seizures but not in the matrix metalloproteinase-9 knock-out mice. (iv) Beta-dystroglycan cleavage correlates in time with increased matrix metalloproteinase-9 activity. (v) Finally, beta-dystroglycan and matrix metalloproteinase-9 colocalize in postsynaptic elements in the hippocampus. In conclusion, our data identify the beta-dystroglycan as a first matrix metalloproteinase-9 substrate digested in response to enhanced synaptic activity. This demonstration may help to understand the possible role of both proteins in neuronal functions, especially in synaptic plasticity, learning, and memory.
Green Building Performance Evaluation: Measured Results from LEED-New Construction Buildings (2008)

Is LEED delivering actual energy savings? This study addresses that question with a post-occupancy assessment of 121 LEED buildings across the country. Input to the study consisted of energy bills and brief descriptions of actual building use from owners, plus modeled energy usage information from the USGBC’s LEED submittal files. The actual building performance was viewed through several whole-building metrics: energy use intensity (EUI) relative to national averages, Energy Star ratings, and energy use levels relative to the initial ASHRAE 90.1 modeling. Two overall results emerged. First, across each of these varied measurements, LEED building performance averaged 25 – 30% better than the benchmark. However, there is also wide variation within the individual results, even for similar building activities and climate zones, suggesting potential for significant further improvements. This paper presents general EUI patterns, Energy Star ratings, and their relationship to LEED energy credits. (Further discussion of the effectiveness of the initial modeling as a tool to predict energy savings is presented as a separate paper.) The discussion also covers the study process and current challenges to such efforts. As an incentive to participate in this aggregate study, owners were given a report of their individual building results including, where desired, an optional occupant survey to further round out the view of building performance.
<i>In vivo</i> efficacy of STI571 in xenografted human small cell lung cancer alone or combined with chemotherapy (2004)

STI571, or imatinib, selectively inhibits BCR/ABL, PDGFR and c-kit kinase activity. It has been reported that a large proportion of small cell lung cancer (SCLC) cell lines and tumors express c-kit and that STI571 inhibits tumor cell growth. We therefore investigated the therapeutic efficacy of STI571, alone or combined with chemotherapy, in human SCLC cells or tumors xenografted into nude mice. The level of c-kit mRNA expression was variable in SCLC tumors (positive for 2 of 4 xenografts), and c-kit protein was not detected by immunohistochemistry. On the 4 xenografted tumors, PDGFRalpha and PDGFRbeta were not detected by immunohistochemistry. STI571 induced inhibition of proliferation of the SCLC6 cell line without inducing apoptosis; in contrast, in combination with etoposide or topotecan, the growth inhibition of SCLC6 cells induced by STI571 was increased, with apoptotic DNA fragmentation. Four human SCLC xenografts (SCLC6, SCLC61, SCLC74 and SCLC108) were transplanted into mice. After intraperitoneal injection of STI571, we observed 80%, 40% and 78% growth inhibition of SCLC6, SCLC61 and SCLC108 tumors, respectively, without any significant inhibition of SCLC74 tumor growth. In mice bearing responsive SCLC tumors, we observed an increase of growth inhibition induced by chemotherapy (etoposide + ifosfamide or topotecan) by concomitant and continuous administration of STI571, associated with an increase of toxic deaths. In SCLC6-bearing mice receiving sequential treatments, we observed a reduction of toxic deaths but a decrease of synergistic antitumor efficacy. In conclusion, the efficacy of STI571 alone in SCLC xenografted tumors was variable and did not depend on c-kit expression. Moreover, a significant increase of chemotherapy-induced growth inhibition was obtained by concomitant administration of STI571 that should be carefully investigated in SCLC patients.
Practical Techniques for Measuring MEMS Properties (2004)

We propose practical analysis techniques to accurately measure geometric, dynamic, and material properties of MEMS. Analytical methods and test structures are presented to extract over a dozen properties by electric probing in a minimal chip area. Geometric properties include fabrication error with respect to layout geometry such as beam widths, gap spacings, etch holes, and beam lengths. Dynamic properties include mass, damping, stiffness, bulk compliance, quality factor, exponential damping factor, displacement amplitude, velocity amplitude, comb drive force, and fringing field factor. Material properties include Young’s modulus, residual stress, shear modulus, Poisson’s ratio, and material density. These techniques differ from those currently available in practicality and that no geometric, dynamic, or material property values are presumed. Only capacitively-based measurements are required.
Application of Grey Prediction Model for Failure Prognostics of Electronics (2010)

Abstract: Reliability prediction is becoming more and more important for electronics components and devices, such as avionics. In this paper, a grey prediction model based prognostics approach was developed to perform the failure prediction of electronics. The grey prediction model first makes the original data set into a new data set with less randomness in order to find the tendency. Then, history data is needed for training the algorithm and predicting the future condition. Last, the predicted result in the new data set is transferred back to the original data set. Compared with traditional data-driven method, this approach was especially useful for reliability prediction with small sample size. The whole prognostics approach was also verified by two case studies. One was performed on electronic boards with ball grid array (BGA) and quad flat package (QFP) components under thermal cycle loading. The other was performed on electronic boards with capacitors under temperature, humidity and bias tests.
1-phenyl-1H-pyrazole derivatives with antiinflammatory, analgesic and antipiretic activities. (1990)

Reaction of ethyl or methyl 2-dimethylaminomethylene-3-oxoalkanoates 2 with phenylhydrazine gave the corresponding esters of 5-substituted 1-phenyl-1H-pyrazole-4-carboxylic acids 3 in high yields. Esters 3 were hydrolyzed to the relative carboxylic acids 4, which were converted by heating to 5-substituted 1-phenyl-1H-pyrazoles 5 in excellent yields. Reaction of methyl 5,5-dimethyl-3-dimethylaminomethylene-2,4-dioxohexanoate with phenylhydrazine afforded methyl 1-phenyl-4-pivaloyl-1H-pyrazole-5-carboxylate 8 b, which was converted as above to the corresponding carboxylic acid 10 b and this to 1-phenyl-4-pivaloyl-1H-pyrazole 11 b. Starting from 5-methoxymethyl-1-phenyl-1H-pyrazole, 1-phenyl-1H-pyrazole-5-acetic acid 18 and its alpha-methyl derivative 19 were also synthesized. Compounds 18, 19, 10 b and 11 b showed a strong antiinflammatory activity in rats; the same compounds in general as well as 8 b, showed appreciable analgesic and antipyretic activities in mice and rats, respectively.
Graphical Design of Primers with PerlPrimer (2007)

PerlPrimer is a cross-platform application for the design of standard PCR, bisulfite PCR, real-time PCR, and sequencing primers. The program combines accurate primer-design algorithms with powerful interfaces to commonly used Internet databases, such as sequence retrieval from the Ensembl genome databases and the ability to BLAST search primer pairs. The use of PerlPrimer for designing primers is described, together with a synopsis of the primer search and primer-dimer algorithms.
Synthesis and Properties of Low-Polydispersity Poly(sulfopropylbetaine)s and Their Block Copolymers (1999)

A series of near-monodisperse sulfopropylbetaine homopolymers have been prepared by reaction of 1,3-propanesultone with poly(2-(dimethylamino)ethyl methacrylate)s produced by group-transfer polymerization. Block copolymers of 2-(dimethylamino)ethyl methacrylate and n-alkyl methacrylates gave sulfobetaine block copolymers when treated with 1,3-propanesultone. Betaine formation dramatically reduces the surface activity of both the homopolymers and the block copolymers. Chromatography and light scattering show that the betaine copolymers form polydisperse micelles on direct dissolution in water, and preliminary dissolution in a nonselective solvent (2,2,2-trifluoroethanol) is needed to give near-monodisperse micelles. Micelle aggregation numbers are controlled by the length of the hydrophobic block and are essentially independent of the hydrophilic block. The betaine homopolymers show chain expansion in aqueous NaCl solutions up to 0.1 M, due to the anti-polyelectrolyte effect. A similar effect is also observed for the block copolymer micelles, which expand significantly with increasing salt concentration up to 0.1 M.
Synthesis of novel nanostructured γ-Al<sub>2</sub>O<sub>3</sub>by pyrolysis of aluminiumoxyhydride–HAlO (2003)

Thermolysis of amorphous nanosized aluminiumoxyhydride, HAlO, at 450 °C led to its decomposition into amorphous Al2O3, finely divided aluminium metal, and H2 gas. Thermolysis at 800–1100 °C afforded γ-Al2O3 nanorods consisting of aggregated nanocrystallites. The size of the nanorods varied between diameters of 30–300 nm and lengths of up to several µm leading to aspect ratios of 3–30. The onset of crystallization was at approximately 800 °C. Yields of up to 40% were obtained by thermolysis at 1100 °C for 6 h. Lower temperatures resulted in lower nanorod yield. The presence of aluminium metal appears to be crucial since no nanorod formation took place in the absence of it. The products were characterized by FTIR spectroscopy, X-ray diffraction and transmission electron microscopy (TEM).
Microsoft smart tags (2002)

This paper describes the latest instantiation of the open hypermedia concept of the generic link as it appears in Microsoft™ Office products - the Smart Tag. We review the background to generic linking and the technology involved in Smart Tags and discuss the reaction to this application in the computing press. Recommendations are made on how the system design could be improved for our purposes.
Factor-Graph Algorithms for Equalization (2007)

In this paper, we use the factor-graph framework to describe the statistical relationships that arise in the equalization of data transmitted over an intersymbol interference channel, and use it to develop several new algorithms for linear and decision feedback approaches. Specifically, we examine both unconstrained and constrained linear equalization and decision feedback equalization of a sequence of nonidentically distributed symbols that are transmitted over a linear, possibly time-varying, finite-length channel and then corrupted by additive white noise. Factor graphs are used to derive algorithms for each of these equalization tasks, including fast implementations. One important application of these algorithms is linear turbo equalization, which requires a linear equalizer that can process observations of nonidentically distributed transmitted symbols. We show how the output of these factor-graph-based algorithms can be used in an efficient implementation of a linear turbo equalizer
A Comparison of Time-domain Time-scale Modification Algorithms (2006)

This convention paper has been reproduced from the author&apos;s advance manuscript, without editing, corrections, or consideration by the Review Board. The AES takes no responsibility for the contents. Additional papers may be obtained by sending request
Plasma microRNAs, miR-223, miR-21 and miR-218, as Novel Potential Biomarkers for Gastric Cancer Detection (2012)

Plasma miR-223, miR-21 and miR-218 are novel potential biomarkers for GC detection.
A New Driving Principle for Micromechanical Torsional Actuators (1999)

Abstract An electrostatic driving principle for micromechanical torsional actuators is presented which allows to excite mechanical oscillations with large deflection angles at low driving voltages. This is achieved by a special electrode configuration which enables the usage of small electrode gaps. The functionality is demonstrated by various 1D-scanner chips which are fabricated in a CMOS-compatible process. When the excitation is synchronized with the oscillation a maximum deflection angle is obtained. For this case a theoretical description of the characteristic curve is given and compared to experimental results. Furthermore, FEM calculations on the deflection dependence of the capacitance are presented.
14-3-3 Proteins in Lewy Bodies in Parkinson Disease and Diffuse Lewy Body Disease Brains (2002)

Several components of Lewy bodies have been identified, but the precise mechanism responsible for the formation of Lewy bodies remains undetermined. The 14-3-3 protein family is involved in numerous signal transduction pathways and interacts with alpha-synuclein, which is a major constituent of Lewy bodies. To elucidate the role of 14-3-3 proteins in neuro-degenerative disorders associated with Lewy bodies, we performed immunohistochemical studies on 14-3-3 in brains from 5 elderly control subjects and from 10 patients with Parkinson disease (PD) or diffuse Lewy body disease (DLBD). In the normal controls, 14-3-3-like immunoreactivity was mainly observed in the neuronal somata and processes in various cortical and subcortical regions. In the PD and DLBD cases, a similar immunostaining pattern was found and immunoreactivity was generally spared in the surviving neurons from the severely affected regions. In addition, both classical and cortical Lewy bodies were intensely immunolabeled and some dystrophic neurites were also immunoreactive for 14-3-3. Our results suggest that 14-3-3 proteins may be associated with Lewy body formation and may play an important role in the pathogenesis of PD and DLBD.
Internet resource discovery services (1993)

An overview of resource discovery services currently available on the Internet is presented. The authors concentrate on the following discovery tools: the Wide Area Information Servers (WAIS) project, Archie, Prospero, Gopher. The World-Wide Web (WWW), Netfind, the X.500 directory, Indie, the Knowbot Information Service (KIS), Alex, Semantic File Systems, and Nomenclator. The authors summarize the surveyed tools by presenting a taxonomy of their characteristics and design decisions. They also describe where to find and how to access several of the surveyed discovery services. They conclude with a discussion of future directions in the area of resource discovery and retrieval.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Conformations and structures of tetra-O-alkyl-p-tert-butylcalix[4]arenes. How is the conformation of calix[4]arenes immobilized? (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConformations and structures of tetra-O-alkyl-p-tert-butylcalix[4]arenes. How is the conformation of calix[4]arenes immobilized?Koji Iwamoto, Koji Araki, and Seiji ShinkaiCite this: J. Org. Chem. 1991, 56, 16, 4955–4962Publication Date (Print):August 1, 1991Publication History Published online1 May 2002Published inissue 1 August 1991https://pubs.acs.org/doi/10.1021/jo00016a027https://doi.org/10.1021/jo00016a027research-articleACS PublicationsRequest reuse permissionsArticle Views2099Altmetric-Citations331LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Monomeric Sarcosine Oxidase:  Role of Histidine 269 in Catalysis<sup>,</sup> (2002)

Conservative mutation of His269 (to Asn, Ala, or Gln) does not-significantly affect the expression of monomeric sarcosine oxidase (MSOX), covalent flavinylation, the physicochemical properties of bound FAD, or the overall protein structure. Turnover with sarcosine and the limiting rate of the reductive half-reaction with L-proline at pH 8.0 are, however, nearly 2 orders of magnitude slower than that with with wild-type MSOX. The crystal structure of the His269Asn complex with pyrrole-2-carboxylate shows that the pyrrole ring of the inhibitor is displaced as compared with wild-type MSOX. The His269 mutants all form charge-transfer complexes with pyrrole-2-carboxylate or methylthioacetate, but the charge-transfer bands are shifted to shorter wavelengths (higher energy) as compared with wild-type MSOX. Both wild-type MSOX and the His269Asn mutant bind the zwitterionic form of L-proline. The E(ox).L-proline complex formed with the His269Asn mutant or wild-type MSOX contains an ionizable group (pK(a) = 8.0) that is required for conversion of the zwitterionic L-proline to the reactive anionic form, indicating that His269 is not the active-site base. We propose that the change in ligand orientation observed upon mutation of His269 results in a less than optimal overlap of the highest occupied orbital of the ligand with the lowest unoccupied orbital of the flavin. The postulated effect on orbital overlap may account for the increased energy of charge-transfer bands and the slower rates of electron transfer observed for mutant enzyme complexes with charge-transfer ligands and substrates, respectively.
Optical Fiber Multiservice Subscriber Connection System: SAFO (1982)

New services using moving pictures will be rapidly increasing within a few years. In a first analysis, they can be classified into three main categories: one-way broadcasted services; one-way video request services; and two-way interactive services. An important issue in their success is the cost of furnishing them. A SAFO project was undertaken to examine such service offerings, utilizing optical fiber and digital technologies. This paper describes the progress made to date by SAFO.
Saitoella, a new anamorph genus in the Cryptococcaceae to accommodate two himalayan yeast isolates formerly identified as Rhodotorula glutinis. (1987)

A description and two illustrations are presented of a new anamorph genus, Saitoella, in the Cryptococcaceae represented by a single species S. complicata sp. nov. to accommodate two yeast strains isolated from Himalayan soil. These were formerly identified as Rhodotorula glutinis (Fres.) Harrison. This genus can be distinguished from Cryptococcus, Rhodotorula, Phaffia, Sterigmatomyces, Fellomyces, and Sporobolomyces by a combination of characters. Saitoella is considered to be ascomycetous in the light of a negative Diazonium Blue B (DBB) reaction and a cell wall ultrastructure typical of ascomycetous yeasts; there is probably a close relationship between Saitoella and Taphrinales on the basis of the formation of carotenoid pigments, the absence of xylose in the cells, the DNA base composition in the "grey zone, " a Q-10 uniquinone system, and a negative DBB reaction.
Significant Enhancement of Thermal Conductivity in Nanofibrillated Cellulose Films with Low Mass Fraction of Nanodiamond (2017)

High thermal conductive nanofibrillated cellulose (NFC) hybrid films based on nanodiamond (ND) were fabricated by a facile vacuum filtration technique. In this issue, the thermal conductivity (TC) on the in-plane direction of the NFC/ND hybrid film had a significant enhancement of 775.2% at a comparatively low ND content (0.5 wt %). The NFC not only helps ND to disperse in the aqueous medium stably but also plays a positive role in the formation of the hierarchical structure. ND could form a thermal conductive pathway in the hierarchical structures under the intermolecular hydrogen bonds. Moreover, the hybrid films composed of zero-dimensional ND and one-dimensional NFC exhibit remarkable mechanical properties and optical transparency. The NFC/ND hybrid films possessing superior TC, mechanical properties, and optical transparency can open applications for portable electronic equipment as a lateral heat spreader.