gebhart/patrepeval huggingface dataset:
Activation of NF-kappa B by the HTLV-I trans-activator protein Tax requires an additional factor present in lymphoid cells. (1989)

The Tax protein of human T-cell leukemia virus is a potent transcriptional activator of viral and cellular genes, including the genes for interleukin 2 and interleukin 2 receptor alpha chain (IL2R alpha). The NF-kappa B protein has been implicated in Tax-mediated activation of IL2R alpha gene expression. We show that activation of NF-kappa B by Tax is an indirect process that requires prior activation of a preexistent factor that is present in lymphoid cells. Deletion mutagenesis revealed that the carboxyl-terminal acidic region of Tax is required for activation of IL2R alpha-directed gene expression but dispensable for activation of the long terminal repeat (LTR). Our findings suggest that activation of viral and cellular gene expression by Tax is achieved through a cascade of events that involves multiple protein-protein associations and that the specificity of these associations is conferred through different domains of the Tax protein.
Constructing iterative non-uniform B-spline curve and surface to fit data points (2004)

In this paper, based on the idea of profit and loss modification, we present
the iterative non-uniform B-spline curve and surface to settle a key problem in computer
aided geometric design and reverse engineering, that is, constructing the curve (surface)
fitting (interpolating) a given ordered point set without solving a linear system. We start
with a piece of initial non-uniform B-spline curve (surface) which takes the given point set
as its control point set. Then by adjusting its control points gradually with iterative formula,
we can get a group of non-uniform B-spline curves (surfaces) with gradually higher
precision. In this paper, using modern matrix theory, we strictly prove that the limit curve
(surface) of the iteration interpolates the given point set. The non-uniform B-spline curves
(surfaces) generated with the iteration have many advantages, such as satisfying the
NURBS standard, having explicit expression, gaining locality, and convexity preserving,
etc
WattsApp: Power-Aware Container Scheduling (2020)

Containers are popular for deploying workloads. However, there are limited software-based methods (hardware- based methods are expensive) for obtaining the power consumed by containers to facilitate power-aware container scheduling. This paper presents WattsApp, a tool underpinned by a six step software-based method for power-aware container scheduling to minimize power cap violations on a server. The proposed method relies on a neural network-based power estimation model and a power capped container scheduling technique. Experimental studies are pursued in a lab-based environment on 10 benchmarks on Intel and ARM processors. The results highlight that power estimation has negligible overheads - nearly 90% of all data samples can be estimated with less than a 10% error, and the Mean Absolute Percentage Error (MAPE) is less than 6%. The power-aware scheduling of WattsApp is more effective than Intel's Running Power Average Limit (RAPL) based power capping as it does not degrade the performance of all running containers.
Motion based unsharp masking [MUSM] for extracting building from urban images (2008)

Classification of remote sensing images from urban area as a means to achieve necessitated information for some applications such as automatic map updating and GIS, planning and emergency response has become one of the challenging subjects for image processing researches. In this paper, a method for classification of remote sensing image from urban area is addressed. First, motion based unsharp masking [MUSM] is applied to the input image to enhance its high frequency components. Then, laplacian of image as input feature for the Bayesian classifier is utilized. After that, size filter is used for large and small building discrimination. The classification of small and large building using unsharp mask and Bayesian discrimination function has increased in aspect of accuracy in comparison with original Bayesian method for classification of urban area. Experiments justify the efficiency of the proposed approach.
Genome Sequence of the Probiotic Strain Lactobacillus rhamnosus (Formerly Lactobacillus casei) LOCK908 (2014)

Lactobacillus rhamnosus LOCK908, a patented probiotic strain (Polish patent no. 209987), was isolated from the feces of a healthy 6-year-old girl. Here, we present the complete genome sequence of LOCK908 and identify genes likely to be involved in the biosynthesis of exopolysaccharides (EPSs).
Prediction of groundwater quality in Pu'er emergency water source by numerical simulation (2012)

With the increasing probability of public critical incident, the common water use crisis is a heavy problem must be faced by each city. So to construct emergency-type water source is an important task of all levels administration departments of water sector. To assess the planning constructing emergency-type water source can ensure the reasonable selection of water source. The main water use is from the surface water reservoirs and the quantity of groundwater exploitation is about 8,000m3/d and the degree of exploitation and utilizing of groundwater is low, so the groundwater in Pu'er city is being planed as a big emergency type wells field. For an emergency type wells field, the changing of the groundwater quality should be predicted ahead. The numerical model has been used to simulate and predict the groundwater quality changing and some results have been obtained: if the water quality in Simao River will not be aggravated continuously and the abstraction of groundwater is not increased quickly, the polluting speed of the groundwater is slow and the degree of pollution is low. To the year of 2020, the groundwater can meet the demand of water use when the common water use crisis happened. But in the long run, to improve the quality of water body in Simao River is the most important measurement to maintain the groundwater quality.
Dynamic document processing (1972)

The current role of computers in automatic document processing is briefly outlined, and some reasons are given why the early promise of library automation and of the mechanization of documentation processes has not been fulfilled. A new dynamic document environment is then outlined in which clustered files are searched and information is retrieved following an interactive user-controlled search process. Methods are described for an automatic query modification based on user needs, and for a continuous reorganization of the stored information as a function of earlier file processing and of normal collection growth. The proposed procedures provide powerful tools for information retrieval and for the control of dynamic library collections in which new items are continually added and ones are retired.
Creatine and Its Application as an Ergogenic Aid (1995)

Phosphocreatine (PCr) availability is likely to limit performance in brief, high-power exercise because the depletion of PCr results in an inability to maintain adenosine triphosphate (ATP) resynthesis at the rate required. It is now known that the daily ingestion of four 5-g doses of creatine for 5 days will significantly increase intramuscular creatine and PCr concentrations prior to exercise and will facilitate PCr resynthesis during recovery from exercise, particularly in those individuals with relatively low creatine concentrations prior to feeding. As a consequence of creatine ingestion, work output during repeated bouts of high-power exercise has been increased under a variety of experimental conditions. The reduced accumulation of ammonia and hypoxanthine in plasma and the attenuation of muscle ATP degradation after creatine feeding suggest that the ergogenic effect of creatine is achieved by better maintaining ATP turnover during contraction.
Federation and Revenue Sharing in Cloud Computing Environment (2014)

In Cloud computing, resources such as CPU, RAM, and disk etc. are provided as a service via the Internet. Elasticity is a key feature of Cloud Computing. It aims to enabling a Cloud Service Provider (CSP) to negotiate the possibility to borrow external resources from other CSPs when its own facilities are not able to satisfy a client request. Reciprocally, a CSP may sell some of its unused resources to another CSP in case of under load. Today, Cloud Federation is a key approach considered for Cloud elasticity. In the context of the Easi-Clouds European ITEA 2 research project, we aim to develop Pricing-as-a-Service (PraaS) suited to the Federated Cloud environment. The aim of this paper is twofold. First, we provide a state of the art of the pricing and revenue sharing models in federated environment. We discuss the specifications of Cloud Federation as well as its different drivers and barriers. Three types of pricing strategies (on-demand, spot and reserved) are presented. In the second part, we present the problem of revenue sharing in the federation with some properties we are willing to fulfill. We propose and evaluate our revenue sharing model suited to the Federated environment with numerical analysis via simulation. We compare our approach to the proportional share and the Shapley value method. Finally, we provide and analyze the results of our simulations with our conclusion and perspectives.
Lithium Rocking Chair Batteries: An Old Concept? (1992)

In recent years consistent attention has been devoted to novel types of lithium rechargeable batteries in which the metal anode is replaced by a lithium‐source anode. The general interest in these batteries, often called rocking‐chair batteries, has increased consistently; however, the idea of exploiting the rocking lithium systems for achieving improvements in safety and cycle life is not new, but dates back to the beginning of the eighties. In this paper we critically review the progress in this area and discuss the impact that rocking chair systems may have on the future of lithium battery technology.
Effects of morin on the pharmacokinetics of etoposide in 7,12-dimethylbenz[a]anthracene-induced mammary tumors in female Sprague-Dawley rats (2012)

Etoposide, used for the treatment of breast cancer, is mainly metabolized via hepatic cytochrome P450 (CYP) 3A4 in humans and is also a substrate for p-glycoprotein (P-gp). Morin is known to be able to modulate the activities of metabolic enzymes including CYPs and can act as a potent P-gp inhibitor. The purpose of this study was to investigate the effects of morin on the pharmacokinetics of etoposide in rats with 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumors. Etoposide was administered intravenously (2 mg/kg) and orally (10 mg/kg) in control and DMBA rats without (DMBA-WOM) and with (DMBA-WM) morin (15 mg/kg). Protein and mRNA expression of CYP3A and P-gp was analyzed, and the tissue distribution of etoposide was also measured. Both protein and mRNA expression of CYP3A and P-gp was inhibited by morin in the liver, intestine and breast tumors of DMBA-WM rats. After both intravenous and oral administration of etoposide in DMBA-WM rats, the total area under the plasma concentration-time curve from time zero to infinity (AUC) of etoposide was significantly greater, and the time-averaged total body clearance (CL) of etoposide was significantly slower than those in control and DMBA-WOM rats. The amount of etoposide recovered from each tissue was significantly higher in DMBA-WM rats, especially in the breast tumor, liver and large intestine. No significant differences between control and DMBA-WOM rats were observed. Taken together, greater AUC and slower CL of etoposide in DMBA-WM rats could possibly be due to the inhibition of hepatic CYP3A (intravenous) and mainly due to the inhibition of intestinal CYP3A and P-gp (oral) by morin.
A Fully Integrated Watt-Level Power Transfer System With On-Chip Galvanic Isolation in Silicon Technology (2016)

This paper presents the design and experimental characterization of a power transfer system performing a dc-dc conversion with on-chip galvanic isolation. The converter is operated in the VHF band, which enables fully integration of all the required components in silicon technology. It consists of only two silicon dice, i.e., a power oscillator with an on-chip isolation transformer and a full-bridge rectifier, which are fabricated in 0.35-μm BCD and 0.13-μm CMOS technology, respectively. A thick SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> layer was used, which guarantees galvanic isolation between the transformer windings. A co-design procedure for the system building blocks is proposed, which aims at optimizing the dc-dc converter performance in terms of power efficiency at a given power density. Thanks to the adopted approach, a maximum output power up to 980 mW is demonstrated with a power efficiency of 29.6%. This paper outperforms previously reported integrated inductive step-up converters in terms of power per silicon area (up to 105 mW/mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> ), while providing on-chip galvanic isolation without any discrete devices or post-processing steps.
Immunization by Irradiated <i>Eimeria acervulina</i> (1972)

SYNOPSIS. In 5 experiments the infectivity and immunogenicity for chickens of sporulated oocysts of Eimeria acervulina that had been previously subjected to different levels of gamma radiation was tested. It was found that the irradiation doses can be divided into three groups: a) High dosage levels of over 16,000 rad impair the reproduction of the parasites so that few or no oocysts are discharged and no immunity is produced. b) Low dosage levels of 7,000 rad and less permit reproduction and development of immunity not perceptibly different from that resulting from unirradiated oocysts. c) An intermediate range of levels with the optimum from 9,100–13,700 rad induces attenuation while at the same time assuring sufficient immunogenic response. A dose of 100,000 oocysts or more per bird is required to produce immunity. The optimum irradiation dose increases with the immunizing dose. It was concluded that the development of an irradiated vaccine is possible.
Nuclear Myocardial Perfusion Imaging with a Cadmium-Zinc-Telluride Detector Technique: Optimized Protocol for Scan Time Reduction (2009)

We have established the minimal scan time for a CZT solid-state detector system, which allows 1-d stress/rest MPI with a substantially reduced acquisition time resulting in excellent agreement with regard to uptake and clinical findings, compared with MPI from a standard dual-head SPECT gamma-camera.
Gait identification using cumulants of accelerometer data (2009)

This paper describes gait identification using cumulants of accelerometer data. Accelerometer data of three different walking speeds for each subject (normal, slow and fast) was acquired by a cell phone placed on the person's hip. Data analysis was based on gait cycles that were detected first. Cumulants of order from 1 to 4 with lags from 0 to 10 for second, third and fourth order cumulants were calculated from the cycles and used as feature vectors for classification which was accomplished by support vector machines (SVM). Six healthy young subjects participated in the experiment. According to their gait classification the average recognition rate was 93.1%. A similarity measure for discerning different walking types of the same subject was also introduced using principal component analysis (PCA).
Neural networks for financial forecasting (1995)

When applied to the world of finance, neural networks are automated trading systems, based on mapping inputs and outputs for forecasting probable future values. In Neural Networks for Financial Forecasting - the first book to focus on the role of neural networks specifically in price forecasting - traders are provided with a solid foundation that explains how neural nets work, what they can accomplish, and how to construct, use, and apply them for maximum profit. It is written by an acknowledged authority who is, himself, the developer of several successful networks. Neural Networks for Financial Forecasting enables you to develop a usable, state-of-the-art network from scratch all the way through completion of training. There are spreadsheets and graphs throughout to illustrate key points, and an appendix of valuable information, including neural network software suppliers and related publications.
Tuning a conversation strategy for interactive recommendations in a chatbot setting (2018)

This paper presents a conversation strategy for interactive recommendations using a chatbot. Chatbots have recently been attracting attention for their use as a flexible user interface. To develop an effective chatbot, it is important to determine what kind of questions to ask, what information should be provided, and how to process a user's responses for a given task. In this paper, we target a chatbot that uses a graphical user interface (GUI) and focus on the task of recommending an item that suits a user's preference. We propose a conversation strategy where a chatbot combines questions about a user's preferences and recommendations while soliciting user's feedback to them. The balance between the questions and recommendations is controlled by changing the parameter values. In addition, we propose a simulation model to evaluate the performance of interactive recommendation under different parameter values. The simulation results with a prototype dataset are presented and discussed.
A primary side feedforward control scheme for low power LED driver compatible with Triac dimmer (2012)

This paper proposes a primary side feedforward control scheme for low power Triac dimmable LED driver. The LED driver is based on the Flyback topology operated in constant frequency (CF) DCM mode. The input power is controlled by the proposed control scheme based on the Triac dimming angle, which is not affected by the AC input voltage variation. Therefore the output power and current can be regulated without any isolated feedback circuit. Also, the input current automatically follows the input voltage due to CF DCM operation. With the proposed control method, high efficiency and high power factor can be achieved by eliminating the isolated feedback circuit and the dummy load required for traditional Triac dimmable LED driver. Furthermore, considering the parameters tolerance existed in the practical application, such as LED forward voltage drop and Flyback transformer magnetizing inductance, the output voltage compensation and primary side inductance compensation method for the proposed control schemes are also presented in the paper, which can further improve the control accuracy. The experimental results from a 27V/0.5A prototype verify the theoretical analysis.
Performance Evaluation of Warm- and Hot-Mix Asphalt Mixtures Based on Laboratory and Accelerated Pavement Tests (2012)

A number of warm-mix asphalt (WMA) technologies are used to reduce the temperature at which the asphalt mixtures are produced and compacted, apparently without compromising the performance of the pavement. The main objective of this study is to determine whether the use of an innovative wax-based LEADCAP WMA additive influences the performance of the asphalt mixture, which is produced and compacted at significantly low temperatures. The WMA pavement using LEADCAP additive (WMA-LEADCAP) along with a control HMA pavement was evaluated with respect to their performances of rutting resistance, crack resistance, and viscoelastic property based on the laboratory dynamic modulus test, indirect tensile strength test, and in-door accelerated pavement test (APT) results. With the limited data carried out, the LEADCAP additive is effective in producing and paving asphalt mixture at approximately 30°C lower temperature than a control HMA mixture, and the performances of WMA-LEADCAP pavement are comparable to a control HMA pavement.
Decreased growth in angus steers with a short TG-microsatellite allele in the P1 promoter of the growth hormone receptor gene. (2000)

A polymorphic TG-repeat microsatellite is located 90 base pairs upstream from a major transcription start site in the bovine growth hormone receptor gene. A shorter allele with 11 consecutive TG is common in Bos indicus cattle, whereas longer 16- to 20-TG-repeat alleles predominate in Bos taurus breeds. The purpose of this study was to compare growth and carcass traits between Angus steers that had two of the longer growth hormone receptor alleles with their half-siblings that had one short allele and one of the longer alleles. We genotyped 64 Angus sires with respect to the poly-TG microsatellite and identified six bulls that were heterozygous in that they had one short 11-TG allele and one of the longer alleles. We then grouped 125 steer progeny of these six heterozygous bulls according to their genotypes: only the longer 16- to 20-TG-repeat alleles were found in 73 steer progeny (long/long homozygotes), whereas a short 11-TG allele was paired with one of the longer alleles in 52 progeny (short/long heterozygotes). Contrasts for the long/long homozygotes vs the short/long heterozygotes were significant for weaning weight (17 +/- 4 kg; P < .001) and carcass weight (14 +/- 5 kg; P < .01). Approaching significance (P = .03) was the contrast for USDA marbling score (-.3 +/- .2). No significant differences (P > .05) were detected for contrasts in birth weight (.3 +/- .6 kg), longissimus muscle area (-.2 +/- 1 cm2), or carcass fat depth (-.01 +/- .07 cm). This polymorphism has potential for use in DNA marker-assisted selection programs.
Real-Time Electrical Impedance Variations in Women With and Without Breast Cancer (2014)

The chaotic vascular network surrounding malignant tumors leads to pulsatile blood flow patterns that differ from those in benign regions of the breast. This study aimed to determine if high-speed electrical impedance tomography (EIT) is able to detect conductivity changes associated with cyclic blood-volume changes and to gauge the potential of using these signatures to differentiate malignant from benign regions within the breast. EIT imaging of pulsating latex membranes submerged in saline baths provided initial validation of its use for tracking temporally varying conductivities. Nineteen women (10 with cancer, nine without) were imaged with EIT over the course of several heartbeats in synchrony with pulse-oximetry acquisition. Eight parameters ( rs, ϕ(rt,max), rt,max, Plow:full, Phigh:full, Plow:high) relating the conductivity images and pulse-oximeter signatures were extracted and used as a means of comparing malignant and benign regions of the breast. Significant differences between malignant and benign regions of interest were noted in seven of the eight parameters. The maximum correlation between conductivity and pulse-oximeter signals, rt,max , was observed to be the optimal discriminating parameter with a receiver operating characteristic area under the curve of 0.8 and a specificity of 81% at a sensitivity of 77%. Assessing the dynamic conductivity of breast may provide additional clinical utility to that of standard imaging modalities, but further investigation is necessary to better understand the biophysical mechanisms leading to the observed conductivity changes.