gebhart/patrepeval huggingface dataset:
Film mode matching: a versatile numerical method for vector mode field calculations in dielectric waveguides (1993)

The old film mode matching or transverse resonance method for calculating mode fields in dielectric waveguides is given a new formulation that makes it an efficient, accurate, and general numerical method, ready to exploit standard computer libraries for numerical linear algebra. Both the scalar and the vector field cases are treated for a rather general class of waveguide cross sections, where the method (like the method of lines) is more accurate and more efficient than sophisticated finite-element and finite-difference methods.
Magnetic aspect sensitivity of high‐latitude <i>E</i> region irregularities measured by the RAX‐2 CubeSat (2014)

The second Radio Aurora Explorer (RAX‐2) satellite has completed more than 30 conjunction experiments with the Advanced Modular Incoherent Scatter Radar chain of incoherent scatter radars in Alaska and Resolute Bay, Canada. Coherent radar echoing occurred during four of the passes: three when E region electron drifts exceeded the ion acoustic speed threshold and one during HF heating of the ionosphere by the High Frequency Active Auroral Research Program heater. In this paper, we present the results for the first three passes associated with backscatter from natural irregularities. We analyze, in detail, the largest drift case because the plasma turbulence was the most intense and because the corresponding ground‐to‐space bistatic scattering geometry was the most favorable for magnetic aspect sensitivity analysis. A set of data analysis procedures including interference removal, autocorrelation analysis, and the application of a radar beam deconvolution algorithm mapped the distribution of E region backscatter with 3 km resolution in altitude and ∼0.1° in magnetic aspect angle. To our knowledge, these are the highest resolution altitude‐resolved magnetic aspect sensitivity measurements made at UHF frequencies in the auroral region. In this paper, we show that despite the large electron drift speed of ∼1500 m/s, the magnetic aspect sensitivity of submeter scale irregularities is much higher than previously reported. The root‐mean‐square of the aspect angle distribution varied monotonically between 0.5° and 0.1° for the altitude range 100–110 km. Findings from this single but compelling event suggest that submeter scale waves propagating at larger angles from the main E × B flow direction (secondary waves) have parallel electric fields that are too small to contribute to E region electron heating. It is possible that anomalous electron heating in the auroral electrojet can be explained by (a) the dynamics of those submeter scale waves propagating in the E × B direction (primary waves) or (b) the dynamics of longer wavelengths.
Apex: An engine for dynamic adaptive policy execution (2016)

The advent of “Soft Networking”, where networks are composed of virtual nodes and links, promises to dramatically ease the definition and deployment of networks whilst allowing network applications that are limited only by the imagination of the developers of those applications. In such a dynamic environment, the Autonomic Management pattern supervised by policies has been recognised as holding more promise for management of Soft Networks than traditional techniques. We have proposed Dynamic Adaptive Policies as an approach to give classic policies the dynamicity and flexibility to manage such networks and whatever applications are running on them. In this paper, we describe our ongoing work on Apex, an engine that executes and administers Dynamic Adaptive Policies in a scalable and distributed manner.
Membranes in Chemical Processing a Review of Applications and Novel Developments (1998)

Abstract The recent development of membrane technology will strongly influence the way industry evaluates separation processes in the immediate future. In some fields membranes are already “proven technology” and incorporated in various production lines or purification processes; mainly within the food and dairy industries, water purification and treatment of liquid effluent streams. Smaller membrane modules for medical applications are also common, but large units in the chemical process industry are still rather rare. This article gives a comprehensive overview of current applications, novel developments and potential for the use of membranes in selected industries within energy production, chemical process industry, wastewater treatment and gas purification. A brief summary for applications in industries like food and beverages, phannaceutics and biochemical industry is also presented together with comprehensive references.
Transferrin- and albumin-directed expression of growth-related peptides in transgenic sheep (1991)

Chimeric genes containing either the mouse transferrin (Trf) enhancer/promoter fused to the structural sequences encoding bovine growth hormone (GH) or the mouse albumin (Alb) enhancer/promoter fused to the gene for human growth hormone-releasing factor (GRF) were microinjected into sheep zygotes. A low percentage of resulting transgenic sheep chronically expressed the respective genes, resulting in elevated plasma concentrations of circulating GH or GRF, respectively. Growth hormone-releasing factor expression induced elevated plasma levels of endogenous GH production. In addition, elevated levels of circulating insulin-like growth factor-I were observed in the bovine GH-expressing Trf transgenic sheep. Growth of these founder transgenic sheep relative to controls were not enhanced. In part, this may be due to the development of the diabetic condition exhibited by both transgenic groups. These results demonstrate that the mouse Trf and Alb enhancer/promoters are active in sheep and suggest that alternate strategies for expressing growth-related genes may be required to modulate growth in sheep.
Image-based stereoscopic stylization (2005)

We present a method to generate stylized stereo imagery that effectively communicates shape and distance of the depicted scene objects. We use computer vision techniques to analyze real stereo image pairs. In particular, a region based stereo matching algorithm with symmetrical treatment of occlusions is used to extract a disparity map and successively the depth information of the scene. The reference image is color segmented for the purpose of color stylization and an algorithm combining intensity image edges and depth discontinuities is applied to depict dominant object contours in the image. We use disparity information to propagate stylized color segments to the second view together with the object outlining contours. The stylized image pairs are consistent across the two views and can be easily fused for stereoscopic viewing. The stereoscopic image fusion provides an extra dimension of depth that is absent on the individual images.
Improved laser-heated pedestal growth system for crystal growth in medium and high isostatic pressure environment (1999)

A modified apparatus for single-crystal-fiber growth in an isostatic gaseous environment and for a large range of pressure (100 mbar up to 100 bar) using a floating-zone-type method known as laser-heated pedestal growth is described. The difficulties and advantages of its design are discussed through examples of crystal growth of some oxide materials.
Requirement of heparin for arterial and venous thrombolysis with recombinant tissue-type plasminogen activator (1991)

The effect of concomitant intravenous (IV) heparin (200 U/kg bolus, followed by 100 U/kg/h) on the efficacy of arterial and venous thrombolysis with IV recombinant tissue-type plasminogen activator (rt-PA; 0.5 mg/kg over 1 hour) was investigated in a combined femoral arterial and venous thrombosis model in the dog. The arterial model consisted of a high-grade stenosis, endothelial damage, and a thrombotic occlusion, and the venous model consisted of a 125I-fibrin-labeled blood clot. After a dose-finding pilot study in four dogs, a randomized, prospective, and blind study was performed in 20 animals pretreated with 2.8 mg/kg IV acetyl salicylic acid (ASA). The combination of rt-PA and heparin (group I, n = 10) induced early (less than 30 minutes) arterial reperfusion in seven dogs, late (greater than 30 minutes) reflow in two dogs, and persistent occlusion in one dog. rt-PA alone (group II, n = 10) was associated with early reperfusion in one dog, late reflow in three dogs, and persistent occlusion in six dogs (P = .018). Reocclusion occurred in five of nine reperfused dogs of group I and in one of four reperfused dogs of group II (P = not significant). Venous clot lysis amounted to 81% +/- 4% (mean +/- SEM) for group I and to 49% +/- 7% for group II (P less than .001). Template bleeding times increased moderately, but significantly, in group I (from 2.2 +/- 0.2 minutes at baseline to 7.0 +/- 1.4 minutes at 30 minutes, P = .006), but only marginally in group II (from 2.2 +/- 0.2 minutes to 3.6 +/- 0.7 minutes, P = .09). No systemic fibrinogen depletion was observed. Thus, the concommitant use of heparin with rt-PA accelerates arterial reperfusion and enhances venous thrombolysis in dogs pretreated with ASA. These results, obtained in a randomized prospective study design, add to a growing body of experimental and clinical evidence, indicating that thrombolytic therapy with rt-PA requires concomitant adjunctive IV heparin for optimal efficacy, even in the face of treatment with ASA.
An arf1Δ Synthetic Lethal Screen Identifies a New Clathrin Heavy Chain Conditional Allele That Perturbs Vacuolar Protein Transport in Saccharomyces cerevisiae (1998)

Abstract ADP-ribosylation factor (ARF) is a small GTP-binding protein that is thought to regulate the assembly of coat proteins on transport vesicles. To identify factors that functionally interact with ARF, we have performed a genetic screen in Saccharomyces cerevisiae for mutations that exhibit synthetic lethality with an arf1Δ allele and defined seven genes by complementation tests (SWA1-7 for synthetically lethal with arf1Δ). Most of the swa mutants exhibit phenotypes comparable to arf1Δ mutants such as temperature-conditional growth, hypersensitivity to fluoride ions, and partial protein transport and glycosylation defects. Here, we report that swa5-1 is a new temperature-sensitive allele of the clathrin heavy chain gene (chc1-5), which carries a frameshift mutation near the 3′ end of the CHC1 open reading frame. This genetic interaction between arf1 and chc1 provides in vivo evidence for a role for ARF in clathrin coat assembly. Surprisingly, strains harboring chc1-5 exhibited a significant defect in transport of carboxypeptidase Y or carboxypeptidase S to the vacuole that was not observed in other chc1 ts mutants. The kinetics of invertase secretion or transport of alkaline phosphatase to the vacuole were not significantly affected in the chc1-5 mutant, further implicating clathrin specifically in the Golgi to vacuole transport pathway for carboxypeptidase Y.
Phytochemical Composition and Antioxidant Capacity of Three Malian Medicinal Plant Parts (2009)

This study evaluates the levels of total polyphenolic compounds in three Malian medicinal plants and determines their antioxidant potential. Quantitative and qualitative analysis of polyphenolics contained in plants extracts were carried out by RP-C18 RP-HPLC using UV detector. The antioxidant activity was determined by three tests. They are phosphomolybdenum, DPPH (2,2-diphenyl-1 picrylhydrazyl) and ABTS [2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic)] tests. The total phenolic and the total flavonoid contents varied from 200 to 7600 mg 100 g(-1) dry weight (dw), expressed as gallic acid equivalents and from 680 to 12 300 mg 100 g(-1) dw expressed as catechin equivalents, respectively. The total anthocyanin concentrations expressed as cyanin-3-glycoside equivalent varied from 1670 to 28 388 mg 100 g(-1) dw. The antioxidant capacity was measured by determining concentration of a polyphenolic (in mg ml(-1)) required to quench the free radicals by 50% (IC(50)) and expressed as vitamin C equivalent antioxidant capacity. The IC(50) values were ranked between 2.68 and 8.80 μg ml(-1) of a solution of 50% (v/v) methanol in water. The uses of plants are rationalized on the basis of their antioxidant capacity.
Vacuum sublimation and solvent extraction of polycyclic aromatic compounds adsorbed on carbonaceous materials (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTVacuum sublimation and solvent extraction of polycyclic aromatic compounds adsorbed on carbonaceous materialsUlf R. Stenberg and Tomas E. AlsbergCite this: Anal. Chem. 1981, 53, 13, 2067–2072Publication Date (Print):November 1, 1981Publication History Published online1 May 2002Published inissue 1 November 1981https://pubs.acs.org/doi/10.1021/ac00236a028https://doi.org/10.1021/ac00236a028research-articleACS PublicationsRequest reuse permissionsArticle Views146Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Influence of nutrition on the virulence and stability of the insect pathogenic fungus Metarhizium anisopliae (2004)

Nutrition influenced growth, sporulation, phenotypic stability and virulence of the insect pathogenic fungus, Metarhizium anisopliae.Virulent conidia were produced on nutrient poor or osmotic stress media, while least virulent conidia were produced on nutrient rich media.Repeated subculturing on nutrient rich media caused further attenuation of virulence, however, attenuation was strain dependant.Several strain independent parameters were identified that could be used to monitor the virulence of M. anisopliae conidia during normal production or when developing new inexpensive culture media.Virulent conidia typically had high levels of spore bound Prl, a CN ratio below 5.2:1 and high germination rates.RT-PCR revealed that virulent conidia from insects contained high levels of transcripts of p rl A and other pathogenicity-related genes (e.g.ste 1, try 1 and chy 1).Virulent conidia from 1% yeast extract media had higher levels of transcripts of these pathogenicity-related genes than the least virulent conidia from CN 35:1 medium (= SDA), however, levels were significantly lower than those in insect-derived conidia.This study shows for the first time that passaged inoculum is virulent irrespective of the original culture medium or insect host suggesting that starvation conditions, whether in vivo or in vitro, results in de-repression of Prl and that elevated levels of this enzyme enhance fungal virulence.Nutrition also influenced expression of other pathogenicity determinants e.g.adhesive properties of conidia (hydrophobicity, surface charge) and destruxins production, however, inconclusive relationship between these pathogenicity determinants and nutrition was observed.Nutrition also influenced fungal stability independent of strain.Under similar nutritional conditions, V275 produced fewer sectors than V245.Most sectors were sterile and produced significantly lower quantities of pathogenicity determinants.Careful selection of stable strains and manipulation of cultural conditions could be employed to enhance or stabilize virulence of M. anisopliae.Special thanks also goes to my lab.colleagues particularly Dr. Wang, Dr. Skrobek and Nita Rice for their valuable suggestions, advice and constrictive criticism during day-to-day research activities.I would like to thank everyone in the School of Biological Sciences, UWS for their cooperation, encouragement and providing a
Phase I study of alpha 2-interferon plus doxorubicin in patients with solid tumors. (1986)

Cytotoxic chemotherapy and interferon have shown synergistic antitumor activity in vitro. The purpose of this study was to determine the maximally tolerated dose of doxorubicin given every 3 weeks, in patients receiving recombinant alpha 2-interferon [10 X 10(6) IU/m2 s.c. three times per week (Monday, Wednesday, and Friday)] during the first 2 weeks of each cycle of doxorubicin. Fourteen patients received a total of 41 cycles. Hematological toxicity was dose limiting with granulocytopenia (total granulocyte count, less than 1000) occurring in 50% of patients treated with doxorubicin at 40 mg/m2 and in 25% of patients treated with doxorubicin at 30 mg/m2. Nonhematological toxicities included a flu-like syndrome, alopecia, nausea, vomiting, diarrhea, and transient mild increases in liver function tests. A partial response was seen in one patient with metastatic squamous cell carcinoma of the skin and in another patient with metastatic adenocarcinoma of the pancreas. Concomitant administration of recombinant alpha 2-interferon given on this schedule limits the amount of doxorubicin that can be administered. However, the responses noted in this study are encouraging enough to warrant additional studies of doxorubicin plus recombinant alpha 2-interferon.
Polyacrylamides and Poly(Acrylic Acids) (2000)

Abstract The article contains sections titled: 1. Introduction 2. Raw Materials 3. Production 3.1. Free‐Radical Polymerization 3.2. Polymerization Processes 3.2.1. Solution Polymerization 3.2.2. Inverse Emulsion Polymerization 3.2.3. Suspension Polymerization 3.2.4. Precipitation Polymerization 3.2.5. Polymer‐Analogous Reactions 3.3. Finishing 4. Properties 5. Uses 5.1. Poly(Acrylic Acids) and Their Salts 5.2. Polyacrylamides and Hydrolyzed Polyacrylamides 5.3. Other Polymers 6. Economic Aspects 7. Toxicology, Occupational Health, and Environmental Aspects
Antigen-specific CD8+ T cell clone protects against acute <i>Toxoplasma gondii</i> infection in mice. (1994)

Encephalitis caused by the obligate intracellular protozoan, Toxoplasma gondii, is a major cause of morbidity and mortality in those afflicted with AIDS. The cell-mediated response is critical for host immunity against this parasite. A panel of T cell clones that proliferate in response to a major parasite protein, p30 (SAG-1) were isolated from mice. One of these clones (C3) bearing the CD8+ phenotype was able to induce nearly 100% protection against acute infection when adoptively transferred into naive mice. In contrast, an Ag-specific CD4+ T cell clone (C2) failed to show significant protection in spite of its ability to produce similar quantities of IFN-gamma. Depletion of host CD4+ T cells with mAb had no effect on CD8(+)-mediated adoptive protection, whereas treatment with anti-IFN-gamma completely abrogated this protection. These results indicate that Ag-specific CD8+ T cells in combination with IFN-gamma are able to induce significant protection against acute toxoplasmosis in the experimental murine model.
Evidence of<i>Borrelia</i>Autoimmunity-Induced Component of Lyme Carditis and Arthritis (2005)

We investigated the possibility that manifestations of Lyme disease in certain hosts, such as arthritis and carditis, may be autoimmunity mediated due to molecular mimicry between the bacterium Borrelia burgdorferi and self-components. We first compared amino acid sequences of Streptococcus pyogenes M protein, a known inducer of antibodies that are cross-reactive with myosin, and B. burgdorferi and found significant homologies with OspA protein. We found that S. pyogenes M5-specific antibodies and sera from B. burgdorferi-infected mice reacted with both myosin and B. burgdorferi proteins by Western blots and enzyme-linked immunosorbent assay. To investigate the relationship between self-reactivity and the response to B. burgdorferi, NZB mice, models of autoimmunity, were infected. NZB mice infected with B. burgdorferi developed higher degrees of joint swelling and higher anti-B. burgdorferi immunoglobulin M cross-reactive responses than other strains with identical major histocompatibility complex (DBA/2 and BALB/c). These studies reveal immunological cross-reactivity and suggest that B. burgdorferi may share common epitopes which mimic self-proteins. These implications could be important for certain autoimmunity-susceptible individuals or animals who become infected with B. burgdorferi.
A LIGHTWEIGHT SOFTWARE COMMUNICATIONS ARCHITECTURE (SCA) LAUNCHER IMPLEMENTATION FOR EMBEDDED RADIOS (2003)

The United States Department of Defense has specified a CORBA based Software Communications Architecture (SCA) as part of a procurement specification for the family of Joint Tactical Radio System (JTRS) Cluster radios. The JTRS Cluster radios require a high-assurance, secure architecture employing NSA Type 1 security, Common Criteria (CC) EAL 4+, and other stringent security architecture requirements [2]. The JTRS Cluster radio family includes embedded radios, such as Cluster 5, in which a fully featured, CORBA based SCA may not be economically or operationally feasible. In these situations, a lightweight SCA should be employed. This paper examines one approach – use of a remote waveform launcher – to dramatically reduce SCA run-time memory footprints required in the embedded radio component. The majority of the SCA resides on the remote host, typically a laptop computer of personal digital assistant (PDA). The remote host is less processorand memoryconstrained than the embedded radio(s), and more capable of hosting the SCA core framework (CF), operating environment (OE) and waveform resources. The launcher was prototyped using the open source SCA Reference Implementation (SCARI).
The release of platelet-activating factor from human endothelial cells in culture. (1983)

The release of platelet-activating factor (PAF) from stimulated human endothelial cells (HEC) cultured from normal term, umbilical cord veins is described. HEC in primary cultures released PAF after challenge with A23187, rabbit anti-human factor VIII (RaHu/FVIII), angiotensin II, and vasopressin. HEC subcultures maintained the ability to release PAF in the presence of A23187 and RaHu/FVIII, whereas the release of PAF in response to angiotensin II and vasopressin was not constant and was reduced. Control cultured, smooth muscle cells derived from umbilical cord veins, previously depleted of endothelial cells, did not release PAF under the above-mentioned stimulation. Plastic-adherent or cultured monocytes released PAF with A23187, but not with RaHu/FVIII, angiotensin II, and vasopressin. The release of PAF from HEC in primary cultures required the presence of extracellular cations and the activation of membrane phospholipase A2. PAF release induced by A23187, RaHu/FVIII, angiotensin II, and vasopressin was unaffected by indomethacin, an inhibitor of cyclooxygenase, which, however, favored the release of PAF from HEC stimulated with thrombin, a stimulus that did not affect HEC in the absence of indomethacin. PGI2 inhibited PAF release from stimulated HEC. The relevance of an acetylation process in the biosynthesis of PAF and HEC was supported by the following evidence: 1) the increase in PAF yield in the presence of sodium acetate and, particularly, of acetyl-CoA; 2) the incorporation of [14C]acetate into PAF molecules; 3) the loss of radioactivity and of biologic activity after treatment with phospholipase A2. These results indicate that HEC in culture are able to release PAF and that metabolic pathways similar to those described for leukocytes are involved.