gebhart/patrepeval huggingface dataset:
[Piperazine analogs of aryloxyaminopropanols and a study of their effects on a model of the isolated guinea pig ileum]. (1996)

Seven compounds belonging to the group of aryloxyaminopropanols with carbamate substitution of the aromatic ring and with derivatives of N-phenylpiperazine in the lipophilic part were prepared by a well-tried method. Selected drugs were pharmacologically evaluated by in vitro experiments. Aryloxyaminopropanol drugs confirmed their anti-calcium activity on the intestinal model. Significant anti-calcium activity of agents IIIq and IIIb (pA2 = 6,83 +/- 1,47; 7, 12 +/- 1, 12 was comparable to that found for the standards verapamil and flunarizine. These compounds were selected for in vivo experiments and evaluated for their effect on reperfusion-induced arrhythmias in anaesthetized rats. Results of these evaluations are given in the next article.
Performance Limits of Nanocomposite Transistors &#x00026; Nanobio Sensors: A Bottom-up Perspective (2007)

In this paper we trace the confusion in the field to inappropriate use of effective-media theories to characterize the transistors/sensors, and show that a 'bottom-up' view allows intuitive understanding of these devices as an elementary illustrations of stick-percolation theory (generalized to nonlinear regime) and diffusion-limited aggregation (generalized to transient regime). Our approach guides technology optimization, and in the process - as experimental testbeds - illuminates subtleties of stick-percolation theory and fractal geometry.
State of the Art Review on Hypermedia Issues And Applications (1999)

Machine (HAM) [Consens &amp; Mendelzon, 1989]. It addresses the following issues raised by Halasz: Search and query mechanisms, augmentation of the basic node and link model, virtual structures, computation over the hypertext network, and versioning. Using GraphLog, queries are formulated by drawing graph patterns. These patterns are then searched for in the hypertext network to yield subgraphs. GraphLog is highly expressive and it uses the notions of deductive database theory and descriptive complexity. The language is powerful enough to allow the specification and manipulation of arbitrary subsets of the network and supports the computation of aggregate functions on the subgraphs of the hypertext document. It can support dynamically defined structures as well as inference capabilities. GraphLog is an extension of the graph-based query language called G+. G+ was extended by adding the notions of negation, aggregation, and improved semantics to make it simple, yet powerful. It can express ...
Robust depth-from-defocus for autofocusing in the presence of image shifts (2008)

A new passive ranging technique named Robust Depth-from-Defocus (RDFD) is presented for autofocusing in digital cameras. It is adapted to work in the presence of image shift and scale change caused by camera/hand/object motion. RDFD is similar to spatial-domain Depth-from-Defocus (DFD) techniques in terms of computational efficiency, but it does not require pixel correspondence between two images captured with different defocus levels. It requires approximate correspondence between image regions in different image frames as in the case of Depth-from-Focus (DFF) techniques. Theory and computational algorithm are presented for two different variations of RDFD. Experimental results are presented to show that RDFD is robust against image shifts and useful in practical applications. RDFD also provides insight into the close relation between DFF and DFD techniques.
A Human Rhinovirus Model of Chronic Obstructive Pulmonary Disease Exacerbations (2007)

Chronic obstructive pulmonary disease (COPD) exacerbations are common events that punctuate the natural history of COPD contributing to disease severity progression and being the major cause of COPD-related morbidity and mortality. Currently available pharmacological strategies are only partially effective at reducing or preventing COPD exacerbations. Viral infections are the most frequent cause of COPD exacerbations. The recent development of a human experimental model of rhinovirus-induced COPD exacerbations represents an innovative tool with the potential to increase our understanding of the inflammatory and immunological mechanisms that lead COPD patients to exacerbate after respiratory virus infections. Moreover this model will provide the opportunity to test, in a carefully controlled setting, novel pharmacological compounds with a potential for treating and preventing COPD exacerbations. In this chapter we will focus on the role of viral infections in COPD exacerbations and will discuss preliminary reports regarding the development of this human model of virus-induced COPD exacerbation.
The normal human myometrium has a vascular spatial gradient absent in small fibroids (2006)

A quantitative gradient within the myometrial vascular system, which is absent in fibroids, has been demonstrated. These structural differences between diseased and healthy tissues are probably because of differing expression of angiogenic growth factors and may explain the distribution of particles seen after uterine artery embolization.
A critical review on advanced velocity measurement techniques in pulsating flows (2010)

Velocity measurement in pulsating flows is more difficult than that in steady flows. One problem follows from the necessity to synchronize the measuring instrument with the characteristic of the flow which is not required for steady-flow measurements. The second challenge is high frequency response of the measuring device which is required for high frequency pulsating flow measurements. Because of development of more advanced measurement devices, there has recently been a growing interest in pulsating velocity measurement and the number of papers in this field has increased significantly in recent years. In this review, the most frequently-used advanced techniques for velocity measurement in pulsating flows are surveyed. The characteristics of different pulsating flows as well as the advantages and limitations of the developed techniques are discussed.
Isotype-associated recognition of allergen epitopes and its modulation by antigen dose. (1995)

The existence of competing and blocking IgG antibodies and their interrelationship with IgE antibodies was investigated in the IgE immune response of CBA/J mice to bee venom phospholipase A2 (PLA2) and keyhole limpet haemocyanin (KLH). Minute doses of antigen induced high titres of both IgE and IgG antibodies, whereas large doses elicited high IgG responses but only weak IgE antibody titres. Immunization with minute doses of antigen led to the production of antibodies with class-associated epitope specificities (designated epitopes G for IgG and E for IgE antibodies), and therefore no competition was observed. For IgG antibody production, G epitopes were immunodominant and IgG antibodies directed to E epitopes were produced only after immunization with an increased immunogen dose. Under this condition IgG antibodies recognizing the E epitopes acted as blocking antibodies competing with IgE antibodies for binding to E epitopes, the immunodominant epitopes for the IgE response. The data demonstrate the existance of distinct immunodominant antigenic determinants for IgE and IgG antibodies on PLA2.
Spatial pileup considerations for pixellated gamma-ray detectors (2000)

High-spatial-resolution solid-state detectors being developed for gamma-ray applications benefit from having pixel dimensions substantially smaller than detector slab thickness. This leads to an enhanced possibility of charge partially spreading to neighboring pixels as a result of diffusion (and secondary photon emission) transverse to the drift direction. An undesirable consequence is the effective magnification of the event "size" and the spatial overlap issues which result when two photons are absorbed in close proximity within the integration time of the detector/readout system. In this work, we develop the general statistics of spatial pileup in imaging systems and apply the results to detectors we are developing based on pixellated cadmium zinc telluride (CdZnTe) and a multiplexing application-specific integrated circuit (ASIC) readout. We consider the limitations imposed on total count rate capacity and explore in detail the consequences for the LISTMODE data-acquisition strategy. Algorithms are proposed for identifying and, where possible, resolving overlapping events by maximum-likelihood estimation. The efficacy and noise tolerance of these algorithms will be tested with a combination of simulated and experimental data in future work.
Guidelines for creating framework data for GIS analysis in low‐ and middle‐income countries (2016)

Key Messages While some framework data are available in LMICs, there is a lack of coordinated effort to create and share these data to support health GIS research in these settings. Manual digitizing can be used to generate framework data, and is increasingly becoming cheaper and faster due to widely available free satellite imagery and open mapping standards that allow distributed data capture. Efforts to create framework data should be done in collaboration with local mapping authorities that have the mandate for creating these data at scale.
Bioluminescence in Immobilized Cells for Biomass Detection and Biosensor Applications (2006)

Bioluminescence measurements have become extremely popular because of good sensitivity and the ability to quantitate a wide variety of analytes. Only recently have these measurements gained particular interest in relation to the study of gene expression and regulation. The firefly luciferase system is the most frequently used bioluminescent reaction, in which adenosine triphosphate (ATP) is used to generate light. ATP is often used as a measure of cell biomass, because the intracellular level of ATP is rather constant and is rapidly degraded upon cell death. The bioluminescence principle has been used successfully in a variety of biosensor applications, mostly for the environmental monitoring. In this chapter we describe detection of viable biomass in free and immobilized cells and outline a few applications, where this approach can be used for biosensor construction. We demonstrate the advantages of bioluminescence by two protocols for detection of ATP and viable biomass in free and immobilized cell samples, which have been proved very rapid and accurate. This indicates that bioluminescence measurements are a good indicator of cell viability and can be widely applied in a number of areas such as biotechnology and food industry.
Copolymerization of diethyl 2‐(methacryloyloxy) ethyl phosphate with alkyl acrylates: Reactivity ratios and glass transition temperatures (1988)

Abstract Soluble copolymers of diethyl 2‐(methacryloyloxy) ethyl phosphate (DMP) with methyl methacrylate (MMA), methyl acrylate (MA), ethyl acrylate (EA) and butyl acrylate (BA) were synthesized by radical copolymerization in benzene solution using azobis(isobutyronitrile) (AIBN) as initiator. The monomer reactivity ratios of these systems at 60°C were determined by the conventional schemes using the methods of Fineman–Ross, Joshi‐Joshi, and Kelen–Tüdos. DMP underwent a completely random and azeotropic copolymerization with MMA whereas in its reaction with the other acrylates DMP entered preferentially into the polymer chain. The reactivities of DMP‐terminated polymer radicals towards the acrylate monomers were found to be in the order: MMA > EA > MA > BA. An increase in solvent polarity decreased the relative reactivity of DMP for the DMP‐MMA pair. An examination of the molecular weights of the copolymers revealed the occurrence of chain transfer caused by DMP. The copolymer glass transition temperatures were determined and the variations of T g with copolymer compositions were discussed according to the theory of Johnston, taking into account the effect of the sequence distributions of the comonomers on T g . The T g s of the alternating copolymers of DMP with the four alkyl acrylates were calculated.
The only thing committees have to fear (1991)

RETURN TO ISSUEPREVNewsNEXTThe only thing committees have to fearCite this: Chem. Eng. News 1991, 69, 10, 29–30Publication Date (Print):March 11, 1991Publication History Published online12 November 2010Published inissue 11 March 1991https://doi.org/10.1021/cen-v069n010.p029Copyright © 1991 AMERICAN CHEMICAL SOCIETYArticle Views5Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (163 KB) Get e-Alerts
Chain Resolution In Hebrew V(P)‐fronting (2006)

Abstract. The copy theory of movement receives the strongest form of support from instances of movement leaving phonetically visible copies. Such is the case in Hebrew V(P)‐fronting, where the fronted verb surfaces as an infinitive, and its “trace” is pronounced as an inflected verbal copy. This paper argues that V‐doubling is explained by the same algorithm that determines pronunciation of single copies in canonical chains. The phonetic resolution of chains is PF‐internal, strictly local, and need not appeal to cross‐interface recoverability constraints. Crosslinguistic variation in predicate clefts largely reflects different morpho‐phonological strategies of realizing the fronted predicate head.
An immediate after-backprojection filtering method with blob-shaped window functions for voxel-based iterative reconstruction (2006)

Blobs have better resolution-noise performance than voxels because of the overlapping of their rotational symmetric basis functions; however, using blobs is more computationally costly than using voxels due to blob overlap. We propose an immediate after-backprojection filtering method (ABF) with blob-shaped window functions for a voxel-based reconstruction. We compared this method with the general voxel-based method (without filtering), the blob-based method, the voxel-based method with between-iteration filtering (BIF) and with post-filtering (POF), using computer simulations. The reconstruction quality was measured by the contrast recovery coefficient (CRC) versus the background noise. It is shown that the ABF method with blob windows is characterized by less image noise and preserved image contrast in comparison with both the general voxel-based method and the voxel-based method with BIF. When using a standard blob window a = 2.0, alpha = 10.4 and m = 2, the ABF method achieves identical CRC-noise features to the blob-based method with "standard" blobs. In addition, the ABF method can be combined with the POF method to achieve better noise-resolution performance than the general voxel-based POF method. The computational cost of the ABF method is slightly greater than that of the general voxel-based method, but much less than the blob-based method.
Multiple-Quantum Filtered Xenon-131 NMR as a Surface Probe (1998)

It is shown how the interface between solid surfaces and cavities filled with gaseous ${}^{131}\mathrm{Xe}$ can be probed by multiple-quantum filtered NMR. Physisorbed ${}^{131}\mathrm{Xe}$ is usually not directly observable by NMR spectroscopy, but information can be transferred into the gas phase through desorption. The exchange process may lead to higher-rank order of the nuclear spins in gaseous xenon which can be detected by multiple-quantum filtered NMR.
Learning a Discriminative Feature Network for Semantic Segmentation (2018)

Most existing methods of semantic segmentation still suffer from two aspects of challenges: intra-class inconsistency and inter-class indistinction. To tackle these two problems, we propose a Discriminative Feature Network (DFN), which contains two sub-networks: Smooth Network and Border Network. Specifically, to handle the intra-class inconsistency problem, we specially design a Smooth Network with Channel Attention Block and global average pooling to select the more discriminative features. Furthermore, we propose a Border Network to make the bilateral features of boundary distinguishable with deep semantic boundary supervision. Based on our proposed DFN, we achieve state-of-the-art performance 86.2% mean IOU on PASCAL VOC 2012 and 80.3% mean IOU on Cityscapes dataset.
The role of CD40 ligand in systemic lupus erythematosus (2004)

CD40 ligand (CD40L, also known as CD154 or gp39) is a member of the tumor necrosis superfamily of transmembrane proteins. The interaction of CD40L on activated T cells with its receptor, CD40 on B cells, is necessary for normal immune function, including B cell differentiation, germinal center formation, and antibody isotype switching. Abnormal expression of CD40L in patients with systemic lupus erythematosus (SLE) may contribute to autoantibody production and disease pathogenesis. Although murine models of monoclonal antibodies directed against CD40L initially showed promise, human trials either have failed to demonstrate efficacy or have been associated with adverse events. This review will summarize in vitro and murine model data and human clinical trials involving anti-CD40L monoclonal antibody.
A Lightweight Approach to Coreference Resolution for Named Entities in Text (2005)

This paper presents a lightweight approach to pronoun resolution in the case when the antecedent is named entity. It falls under the category of the so-called knowledge poor approaches that do not rely extensively on linguistic and domain knowledge. We provide a practical implementation of this approach as a component of the General Architecture for Text Engineering (GATE). The results of the evaluation show that even such shallow and inexpensive approaches provide acceptable performance for resolving the pronoun anaphors of named entities in texts.
Latex anaphylaxis during labor : case report (2002)

Allergy to latex gloves has been described as an unusual complication during labor. However, IgE mediated hypersensitivity reaction to natural rubber have recently been identified as an international health problem. In this first case report in Korea, latex anaphylaxis during labor is described in an operating room nurse who has been continuously exposed to latex gloves. Because of the increasing frequency of latex allergy, obstetrician should take care and give more attention to the clinical history, as well as be aware of this possibility especially in high risk groups.
GRACE-2: integrating fine-grained application adaptation with global adaptation for saving energy (2009)

Energy efficiency has become a primary design criterion for mobile multimedia devices. Prior work has proposed saving energy through coordinated adaptation in multiple system layers, in response to changing application demands and system resources. The scope and frequency of adaptation pose a fundamental conflict in such systems. The Illinois GRACE project addresses this conflict through a hierarchical solution which combines: 1) infrequent (expensive) global adaptation that optimises energy for all applications in the system, 2) frequent (cheap) per-application (or per-app) adaptation that optimises for a single application at a time. This paper demonstrates the benefits of the hierarchical adaptation through a second-generation prototype, GRACE-2. Specifically, it shows that in a network bandwidth constrained environment, per-app application adaptation yields significant energy benefits over and above global adaptation.
Single-step synthesis of manganese oxide octahedral molecular sieves with large pore sizes (2010)

A facile single-step method was developed for synthesizing todorokite-type manganese oxide octahedral molecular seieves (OMS-1) and 2 x 4 tunnel structured manganese oxide (OMS-5) materials. Selection of starting materials and initial pH conditions in the syntheses are crucial.
Role of water in the hydrolysis of parathion and methylparathion on kaolinite (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRole of water in the hydrolysis of parathion and methylparathion on kaoliniteSarina Saltzman, Uri Mingelgrin, and Bruno YaronCite this: J. Agric. Food Chem. 1976, 24, 4, 739–743Publication Date (Print):July 1, 1976Publication History Published online1 May 2002Published inissue 1 July 1976https://pubs.acs.org/doi/10.1021/jf60206a011https://doi.org/10.1021/jf60206a011research-articleACS PublicationsRequest reuse permissionsArticle Views161Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effects of Topical and Subconjunctival Bevacizumab in High-Risk Corneal Transplant Survival (2010)

Subconjunctival bevacizumab may offer an adjunctive measure to conventional therapies in preventing graft rejection in high-risk corneal transplantation.
Human Neutrophils as a Source of Nociceptin:  A Novel Link between Pain and Inflammation<sup>,</sup> (2003)

Nociceptin is a neuropeptide sharing sequence homology with classical opioid peptides but with a distinct pharmacological profile. Through activation of its receptor, NociR, nociceptin has been linked with several physiological functions in the central nervous system including memory, locomotion, and processing of pain signals. Recently, peripheral blood neutrophils (PMNs) were demonstrated to express a functional NociR, a result suggesting that additional functions of the neuropeptide remain to be elucidated. The present study investigated the possibility that PMNs may be a source of nociceptin and whether the neuropeptide elicits PMN early responses. We observed the presence of nociceptin in the synovial fluids from arthritic patients, an inflammatory milieu typically containing high numbers of PMNs. In addition, freshly isolated PMNs were found to express and secrete nociceptin following degranulation, identifying these inflammatory cells as a novel source of the neuropeptide. Incubation of PMNs with nociceptin elicited a specific pattern of cellular protein phosphorylation on tyrosine residues in a rapid and transient fashion. Moreover, nociceptin prevented intracellular accumulation of cAMP in fMLP-stimulated PMNs, an effect mimicked by the specific NociR synthetic agonist, Ro 64-6198. Taken together, these results show that nociceptin/NociR is present and functional in human neutrophils, and the results identify a novel dialogue pathway between neural and immune tissues.