gebhart/patrepeval huggingface dataset:
Q-enhancing technique for high speed active inductors (2002)

Integrated active inductor configurations for RF frequencies are examined in this paper. A new aspect of comparing the performance of different topologies is used, and consequent differences between technologies are recognised. On the basis of these studies a new method for raising the Q-factor is presented and its applications considered.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Randomized Trial of N-Acetylcysteine for Prevention of Trimethoprim-Sulfamethoxazole Hypersensitivity Reactions in Pneumocystis carinii Pneumonia Prophylaxis (CTN 057) (1998)

Hydroxylamine derivatives of sulfamethoxazole may be the reactive metabolites that cause adverse reactions to trimethoprim-sulfamethoxazole (TMP-SMX). The increased frequency of reactions observed in HIV-positive individuals is hypothesized to be due to systemic glutathione deficiency and a decreased ability to scavenge these metabolites. Two hundred and thirty-eight patients were randomized to receive or not receive N-acetylcysteine (3 g of the 20% liquid solution) 1 hour before each dose of TMP-SMX (trimethoprim 80 mg, sulfamethoxazole 400 mg) twice daily, which was initiated as primary Pneumocystis carinii pneumonia prophylaxis. Forty-five patients had to discontinue TMP-SMX within 2 months because of fever, rash, or pruritus including 25 of 102 patients (25%) who were receiving TMP-SMX alone and 20 of 96 patients (21%) who were randomized to TMP-SMX and N-acetylcysteine. The difference between treatment groups is 4% (95% confidence interval [CI]: -16%, +9%). No independent association was found with the hypersensitivity reaction and age, gender, race, HIV risk factor, prior AIDS, concurrent use of fluconazole, or baseline CD4. N-acetylcysteine at a dose of 3 g twice daily could not be shown to prevent TMP-SMX hypersensitivity reactions in patients with HIV infection.
Road-map assisted ground moving target tracking (2006)

Tracking ground targets with airborne GMTI (ground moving target indicator) sensor measurements proves to be a challenging task due to high target density, high clutter, and low visibility. The exploitation of nonstandard background information such as road maps and terrain information is therefore highly desirable for the enhancement of track quality and track continuity. The present paper presents a Bayesian approach to incorporate such information consistently. It is particularly suited to deal with winding roads and networks of roads. The target dynamics is modeled in quasi one-dimensional road coordinates and mapped onto ground coordinates using linear road segments taking road map errors into account. The case of several intersecting roads with different characteristics, such as mean curvature, slope, or visibility, is treated within an interacting multiple model (IMM) scheme. Targets can be masked both by the clutter notch of the sensor and by terrain obstacles. Both effects are modeled using a sensor-target state dependent detection probability. The iterative filter equations are formulated within a framework of Gaussian sum approximations on the one hand and a particle filter approach on the other hand. Simulation results for single targets taken from a realistic ground scenario show strongly reduced target location errors compared with the case of neglecting road-map information. By modeling the clutter notch of the GMTI sensor, early detection of stopping targets is demonstrated
Multi-video summarization based on AV-MMR (2010)

This paper presents an algorithm for video summarization, Audio Video Maximal Marginal Relevance (AV-MMR), exploiting both audio and video information. It is an extension of the Video Maximal Marginal Relevance (Video-MMR) algorithm which was only based on visual information. AV-MMR iteratively selects segments which best represent unselected information and are non redundant with previously selected information. As for Video-MMR, AV-MMR is a generic algorithm which is suitable for both single and multiple videos with multiple genres. Several variants of AV-MMR are proposed and the best one is identified by experimentation. Besides, a visual representation of the coherence of audio and video information for a set of audio-visual sequences is also proposed.
Automated firmware testing using firmware-hardware interaction patterns (2014)

Firmware is low-level software which can directly access hardware and is often shipped with the hardware platform. This component of the system is increasing in scale and importance, and thus firmware validation is a critical part of system validation. Firmware validation relies on the interacting hardware components which are usually not available until the late design stages. This is generally addressed through co-simulating C/C++ based firmware code and HDL hardware models (including SystemC). However, this tends to be slow, and is further exacerbated by the large number of possible interleavings between the concurrent firmware and hardware threads. Typically, in the co-simulation, the scheduler, such as the SystemC scheduler, will only explore a single, or at best a small number of possible firmware-hardware interleavings and thus may miss critical bugs. In this paper we present an alternative approach to firmware validation that is based on automatically generating a test-set for the firmware with the goal of complete path coverage while considering its interactions with hardware and other firmware threads. It uses a service-function based Transaction Level Model (TLM) which has been used in the past for firmware-hardware codesign. The test generation is based on concolic testing which has been used successfully in software test generation. However, existing concolic testing tools are used for test-generation of sequential code, and cannot directly consider the interaction of other hardware/firmware threads with the target firmware thread during test generation. We address this limitation by exploiting specific interaction patterns between the firmware and hardware threads that can be analyzed from the TLM. We show how these patterns, along with the firmware and hardware threads are used to automatically generate a sequential program that is test-equivalent to the target firmware transaction and that can be used with a standard sequential program concolic test generator. The tests generated can be (i) directly used for the firmware transaction and (ii) account for the multi-threaded interactions. These interaction patterns are practically relevant as they occur often in practice in real firmware benchmarks such as Linux device driver code, and its interacting QEMU emulated hardware code. Finally, we demonstrate the efficacy of our techniques for these benchmarks through a practical implementation that is automated and built on top of Frama-C, a static code analyzer, and KLEE, a concolic testing tool.
Abnormal Involuntary Movements in Schizophrenia (1982)

Abnormal involuntary movements indistinguishable from those now described as tardive dyskinesia were reported in schizophrenic patients by Kraepelin long before the introduction of neuroleptic drugs. Two large surveys of mental hospital patients including patients who had never received neuroleptics also revealed involuntary movements; indeed, the incidence was not substantially different from that in drug-treated patients. This fact casts doubt on the widely held assumption that these movements are persistent and irreversible effects of neuroleptic drugs. In an animal model of dyskinesia, abnormal movements were seen after administration of a phenothiazine and a thioxanthene but not after haloperidol. The syndrome appeared to be unrelated to dopamine receptor blockade or to changes in dopamine receptors. In postmortem striatal tissue from patients with schizophrenia, ligand binding to D-1 and D-2 dopamine receptors was not increased in patients who had been found to have abnormal involuntary movements in comparison with those who did not have such movements; as previously reported, binding to D-2 receptors was increased in patients with schizophrenia in comparison with controls. It is concluded that dyskinetic changes occur as a consequence of the process of schizophrenia and perhaps other diseases. Whether or not persistent and irreversible changes can be caused either in animals or humans by neuroleptic administration has yet to be clearly established. Whether they occur as a manifestation of the disease process or a consequence of drug administration, such dyskinesias are unassociated with changes in D-1 or D-2 receptors.
Quantitative Study of Music Listening Behavior in a Social and Affective Context (2013)

A scientific understanding of emotion experience requires information on the contexts in which the emotion is induced. Moreover, as one of the primary functions of music is to regulate the listener's mood, the individual's short-term music preference may reveal the emotional state of the individual. In light of these observations, this paper presents the first scientific study that exploits the online repository of social data to investigate the connections between a blogger's emotional state, user context manifested in the blog articles, and the content of the music titles the blogger attached to the post. A number of computational models are developed to evaluate the accuracy of different content or context cues in predicting emotional state, using 40,000 pieces of music listening records collected from the social blogging website LiveJournal. Our study shows that it is feasible to computationally model the latent structure underlying music listening and mood regulation. The average area under the receiver operating characteristic curve (AUC) for the content-based and context-based models attains 0.5462 and 0.6851, respectively. The association among user mood, music emotion, and individual's personality is also identified.
Analysis and design of hierarchical Web caching systems (2002)

This paper aims at finding fundamental design principles for hierarchical Web caching. An analytical modeling technique is developed to characterize an uncooperative two-level hierarchical caching system where the least recently used (LRU) algorithm is locally run at each cache. With this modeling technique, we are able to identify a characteristic time for each cache, which plays a fundamental role in understanding the caching processes. In particular, a cache can be viewed roughly as a lowpass filter with its cutoff frequency equal to the inverse of the characteristic time. Documents with access frequencies lower than this cutoff frequency will have good chances to pass through the cache without cache hits. This viewpoint enables us to take any branch of the cache tree as a tandem of lowpass filters at different cutoff frequencies, which further results in the finding of two fundamental design principles. Finally, to demonstrate how to use the principles to guide the caching algorithm design, we propose a cooperative hierarchical Web caching architecture based on these principles. The simulation study shows that the proposed cooperative architecture results in 50% saving of the cache resource compared with the traditional uncooperative hierarchical caching architecture.
Metal-free Cross-Dehydrogenative Coupling of <i>HN</i>-azoles with α-C(sp<sup>3</sup>)-H Amides via C–H Activation and Its Mechanistic and Application Studies (2016)

A metal-free one step coupling reaction between various N-azole rings and diverse α-C(sp<sup>3</sup>)-H containing amides has been developed under oxidative reaction conditions. Commercially available tetrabutyl ammonium iodide (TBAI) in the presence of terbutylhydroperoxide (TBHP), under neat reaction condition, efficiently catalyzed the coupling. Various azole types, such as 1H-benzotriazoles, 1H-1,2,3-triazoles, 1H-1,2,4-triazoles, 1H-tetrazoles, 1H-pyrazoles, and 1H-benzimidazoles, and α-C(sp<sup>3</sup>)-H containing amides, such as N,N-dimethylacetamide, N,N-dimethylbenzamide, N-methylacetamide, N,N-diethylacetamide, N-methylpyrrolidine, and pyrrolidine-2-one, were successfully employed for the coupling. A series of designed and controlled experiments were also performed in order to study the involvement of the different intermediates. Based on the evidence, a plausible mechanism is also proposed. These novel, simple, rapid, attractive, and straightforward transformations open the way of the construction of novel highly functionalized N-azoles via direct covalent N-H bond transformations onto N-C bonds. This approach allows to the synthesis of complex molecules requiring number of steps using classical synthetic ways. In addition, the range of α-C(sp<sup>3</sup>)-H containing amide substrates is virtually unlimited highlighting the potential value of this simple system for the construction of complex heterocyclic molecules, such as fused azoles derivatives.
Improvements in Cereal Tissue Culture by Thidiazuron: A Review (2007)

This article reviews research to establish highly regenerative cell and tissue culture systems in cereals and grasses as a prerequisite for crop improvement using biotechnological methods. The strategies were described in the historical framework of investigations in this field and then new approaches were discussed focussing on the considerable recent progress made using the cotton defoliant thidiazuron (TDZ) for enhancement of morphogenic competence in the Poaceae during the last 15 years. In 1982, TDZ was first described to have cytokinin-like activity and subsequently, numerous studies have characterized this compound as a powerful plant growth regulator for dicots with special emphasis on recalcitrant leguminous and woody species. However, TDZ was evaluated for cereal tissue culture with a remarkable delay. The results summarized clearly showed that TDZ can significantly improve morphogenic response from callus derived from a wide range of explants concerning frequency of shoot formation, number of shoots per explant and the time needed for shoot induction compared to other cytokinins. Moreover, TDZ has been used effectively for establishment of shoot meristematic cultures from model and agronomically important cultivars using shoot apices, shoot meristematic segments as well as nodes and pronounced differences were obtained regarding shortening of the time frame especially for barley and wheat. Besides that, high frequency plant regeneration with long-term retention of morphogenecity in a relatively genotype-independent manner was observed. Nevertheless, in a few cases problems associated with the use of TDZ were noted. The data summarized imply that TDZ is also a potent growth regulator for
Pain and inflammation (1990)

The functional regeneration of C-fibers mediating polymodal nociception and low-threshold mechanoreceptive axons in the lateral plantar nerve (LPN) and the foot branch of the superficial peroneal nerve (fSPN) was evaluated in normal rats and 3 months after unilateral sciatic nerve crush or neurotomy and suture. The area covered by low-threshold mechanoreceptors (LTMs) was tested through gentle mechanical skin stimulation and recording from the relevant nerve. In regenerated animals the glabrous skin area with functional LPN-related LTMs was severely reduced following a crush lesion. Functional receptors of that type were absent after neurotomy and suture. The hairy skin area with fSPN-related LTMs was smaller than normal, particularly following neurotomy and suture. The distribution of polymodal C-fibers was tested through stimulation-induced extravasation of Evans blue albumin (EBA). In the glabrous LPN skin domain the area showing EBA extravasation did not return to normal after any of the lesion types. However, in the hairy fSPN skin area the distribution of EBA extravasation appeared largely normal following both injuries. We conclude that polymodal nociception reappears to a greater extent than low threshold mechanosensitivity, and that both modalities regenerate better in hairy skin than in glabrous skin.
Speech-based localization of multiple persons for an interface robot (2005)

Robots are conveniently controlled by a human operator with spoken commands, since voice is a natural communication medium for humans. In order to successfully carry out a command, a robot needs to know which of the possibly many people gave the command and where this person is located. In this paper, we present a particle-filter based algorithm for localization of multiple speakers, in an environment where there is only one person speaking at a time. The algorithm incorporates person-specific voice features (vowel formant frequencies) in order to distinguish between the speakers. The voice features are supported by azimuth angle measurements obtained by a pair of microphones. We test our approach using the microphone system of the Philips iCat interface robot.
Isolation, characterization, and cDNA sequence of two fatty acid-binding proteins from the midgut of Manduca sexta larvae. (1992)

Two abundant fatty acid-binding proteins (MFB1 and MFB2) were isolated from the midgut cytosol of larval Manduca sexta. As isolated, MFB1 and MFB2 were found to contain bound fatty acids in a 1:1 molar stoichiometric ratio. Immunological screening demonstrated that MFB1 and MFB2 were restricted to the midgut in a gradient distribution, with MFB1 more concentrated in the anterior two-thirds of the midgut and MFB2 more concentrated in the posterior two-thirds of the midgut. MFB1 exchanged fatty acid more readily than did MFB2. MFB1 was about 2% and MFB2 about 12% of the cytosolic protein in the midgut. cDNA clones for MFB1 and MFB2 both encode proteins of 131 amino acids that are rich in lysine and acidic residues. Analysis of the amino acid sequence alignment of the MFBs with six mammalian fatty acid-binding proteins revealed a number of shared features: 9 conserved glycines, presumably important in turns of the beta-strands; a basic amino acid in a position corresponding to the residue reported to participate in binding the carboxyl group of the fatty acid (Arg in MFB1 and Lys in MFB2); and conservation of many of the residues important in binding the aliphatic portion of the fatty acid.
Engine Condition Monitoring Based on Grey AR Combination Model (2010)

Aiming at the problems of the wear condition monitoring, grey theory and auto-regressive combination forecasting model was put forward, and the combination model was build. The rough trend of the wear particle content change can be reflected through grey theory, and the detail of the change can be reflected through auto-regressive model. By testing and comparing a set of Ferro graphic data, the result shows that the combination model has a better forecasting result.
Central effect of endothelin on blood pressure in conscious rats (1989)

This study was conducted to investigate the effect of intracerebroventricular administration of endothelin (EDT), a novel potent vasoconstricting peptide, on blood pressure in conscious rats. The lateral cerebral ventricle of male Wistar rats was cannulated, and the femoral artery was also cannulated to measure the mean arterial blood pressure (MABP) and heart rate (HR). EDT dissolved in 10 microliters of artificial cerebrospinal fluid (ACSF) (8.25-66 pmol icv) provoked a dose-dependent increase in MABP. EDT also increased HR, although the effect of 66 pmol was variable. Intracerebroventricular ACSF did not provoke any effects on MABP and HR. Intracerebroventricular EDT also provoked contralateral rotational behavior. Pretreatment with 2 mg/kg iv phenoxybenzamine significantly suppressed the 16.5 pmol icv EDT-induced increase in MABP. Moreover, 16.5 pmol icv EDT markedly increased plasma epinephrine and norepinephrine concentration. These results indicate that EDT has a central pressor action, and the action might be mediated, at least in part, by catecholamine release to the periphery. EDT might play a role in the central control of blood pressure, although the physiological implications have not yet been determined.
Substance P in Human Essential Hypertension (1987)

Summary: Substance P (SP) plays an important role in central nervous and peripheral blood pressure regulation. Its effects include modulating influence on the adrenergic system and inhibition of stress-induced plasma noradrenaline increase in animal studies. In patients with essential hypertension (n = 45, WHO stages 1 and 2) the SP-like immunoreactivity (SPLIR) was found significantly (p < 0.01) lower (1.36 ± 0.23 pg/100 μl) than in 24 normotensive subjects (4.54 ± 0.72 pg/100 μl). Furthermore, the influence of a mental stress test on SPLIR was investigated in patients with essential hypertension (n = 11, WHO stage 1) and compared with nine normotensive subjects. Whereas in normotensive subjects plasma SP increased under a standardized mental arithmetic test (4.03 ± 0.48 to 4.74 ± 0.56 pg/100 μl), in hypertensive patients a decrease of SP from lower baseline levels (2.85 ± 0.54 to 2.57 ± 0.54 pg/100 μl) was demonstrated. The significantly different changes of plasma SP in normotensive and hypertensive subjects under mental stress conditions had the opposite direction in comparison with the adrenergic reaction [higher and prolonged increase of plasma noradrenaline (NA) in the hypertensive group]. Under antihypertensive drug treatment with prazosin (4.5 mg/day, n = 10) or with captopril (450 mg/day, n = 10) an increase of plasma SP was registered. The results support the participation of SP in the pathogenesis of human hypertension and in therapeutic mechanisms. Lower plasma levels and decreased responsiveness of SP possibly represent the enhanced stress sensitivity in primary hypertension.
Antibacterial Properties of Nitric Oxide-Releasing Sol−Gel Microarrays (2004)

ADVERTISEMENT RETURN TO ISSUEPREVNoteAntibacterial Properties of Nitric Oxide-Releasing Sol−Gel MicroarraysKevin P. Dobmeier and Mark H. SchoenfischView Author Information Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 Cite this: Biomacromolecules 2004, 5, 6, 2493–2495Publication Date (Web):October 20, 2004Publication History Received24 June 2004Revised1 September 2004Published online20 October 2004Published inissue 1 November 2004https://pubs.acs.org/doi/10.1021/bm049632uhttps://doi.org/10.1021/bm049632ubrief-reportACS PublicationsCopyright © 2004 American Chemical SocietyRequest reuse permissionsArticle Views433Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Bacteria,Coating materials,Fluxes,Redox reactions,Surface interactions Get e-Alerts