gebhart/patrepeval huggingface dataset:
Phase Unwrapping for 2-D Blind Deconvolution of Ultrasound Images (2004)

In most approaches to the problem of two-dimensional homomorphic deconvolution of ultrasound images, the estimation of a corresponding point-spread function (PSF) is necessarily the first stage in the process of image restoration. This estimation is usually performed in the Fourier domain by either successive or simultaneous estimation of the amplitude and phase of the Fourier transform (FT) of the PSE This paper addresses the problem of recovering the FT-phase of the PSF, which is an important reconstruction problem by itself. The purpose of this paper is twofold. First, it provides a theoretical framework, establishing that the FT-phase of the PSF can be effectively estimated by a proper smoothing of the FT-phase of the appropriate radio-frequency (RF) image. Second, it presents a novel approach to the estimation of the FT-phase of the PSF, by solving a continuous Poisson equation over a predefined smooth subspace, in contrast to the discrete Poisson equation solver used for the classical least mean squares phase unwrapping algorithms, followed by a smoothing procedure. The proposed approach is possible due to the distinct properties of the FT-phases, among which the most important property is the availability of precise values of their partial derivatives. This property overcomes the main disadvantage of the discrete schemes, which routinely use wrapped (principal) values of the phase in order to approximate its partial derivatives. Since such an approximation is feasible subject to the restriction that the partial phase differences do not exceed pi in absolute value, the discrete schemes perform satisfactory only for few practical situations. The proposed approach is shown to be independent of this restriction and, thus, it performs for a wider class of the phases with significantly lower errors. The main advantages of the novel method over the algorithms based on discrete schemes are demonstrated in a series of computer simulations and for in vivo measurements.
Seamless integration of mobile WiMAX in 3GPP networks (2008)

As the wireless industry makes its way to the next generation of mobile systems, it is important to engineer solutions that enable seamless integration of emerging 4G access technologies within the currently deployed and/or evolved 2G/3G infrastructures. In this article we address a specific case of such a seamless integration, that of mobile WiMAX in evolved 3GPP networks. In this context we investigate the architecture and the key procedures that enable this integration, and we also introduce a novel handover mechanism that enables seamless mobility between mobile WiMAX and legacy 3GPP access, such as UTRAN or GERAN. The core characteristic of this novel handover mechanism is that mobile terminals do not need to support simultaneous transmission on both WiMAX and 3GPP accesses; therefore, it mitigates the RF coexistence issues that exist otherwise and improves handover performance. In addition, we provide a brief overview of mobile WiMAX and the evolved 3GPP network technologies, and we set the appropriate background material before presenting our proposed handover mechanism. Our main conclusion is that integrating mobile WiMAX in evolved 3GPP networks is a compelling approach for providing wireless broadband services, and mobility across WiMAX and 3GPP access can become seamless and efficient with no need for mobile terminals to support simultaneous transmission on both types of access.
Antigen Delivery by Lipid-Enveloped PLGA Microparticle Vaccines Mediated by <i>in Situ</i> Vesicle Shedding (2014)

Lipid-coated poly(lactide-co-glycolide) microparticles (LCMPs) consist of a solid polymer core wrapped by a surface lipid bilayer. Previous studies demonstrated that immunization with LCMPs surface-decorated with nanograms of antigen elicit potent humoral immune responses in mice. However, the mechanism of action for these vaccines remained unclear, as LCMPs are too large to drain efficiently to lymph nodes from the vaccination site. Here, we characterized the stability of the lipid envelope of LCMPs and discovered that in the presence of serum the lipid coating of the particles spontaneously delaminates, shedding antigen-displaying vesicles. Lipid delamination generated 180 nm liposomes in a temperature- and lipid/serum-dependent manner. Vesicle shedding was restricted by inclusion of high-TM lipids or cholesterol in the LCMP coating. Administration of LCMPs bearing stabilized lipid envelopes generated weaker antibody responses than those of shedding-competent LCMPs, suggesting that in situ release of antigen-loaded vesicles plays a key role in the remarkable potency of LCMPs as vaccine adjuvants.
Biometric enhancements: Template aging error score analysis (2008)

Identity capabilities are being modernized through biometric technology and systems. With maturing biometrics in full, rapid development, a higher accuracy of identity verification is required. Improvements to the security of biometric verification systems is provided through higher accuracy; ultimately reducing fraud, theft, and loss of resources from unauthorized personnel. With trivial biometric systems, a higher acceptance threshold to obtain higher accuracy rates increased false rejection rates and user unacceptability. However, maintaining the higher accuracy rate enhances the security of the system. Through the methods presented in this paper, higher accuracy rates are obtained without lowering the acceptance threshold, therefore improving the security level, false rejection rates, and user acceptability. An area of biometrics with a paucity of research is template aging, specifically in regards to facial aging. This paper presents methods of modeling and predicting facial template aging based on matching score analysis. A novel foundational framework for facial template aging is presented and provides a methodological framework. The groundwork discusses new techniques used in the template aging framework, to include the ldquoerror score matrixrdquo and ldquodecay error estimaterdquo concepts. The matching scores are calculated using commercially available facial matching algorithms/SDKs against publicly available facial databases. Improved performance error rates while maintaining or improving upon the overall matching and/or rejection levels is accomplished with the new framework. Using such scores, prediction of a timeframe if or when an individual needs to be re-enrolled with a new template is feasible.
Über die elektrophile Substitution von 3(5)‐Amino‐pyrazol (1967)

Abstract 3(5)‐Amino‐pyrazol ( 1 ) wird in 4‐Stellung halogeniert und nitriert. Die Tautomerie von 1 und die Stelle der bevorzugten elektrophilen Substitution werden anhand der NMR‐Spektren diskutiert. Die Acetylierung von 1 am exocyclischen N‐Atom wird IR‐spektroskopisch bewiesen.
Effect of Respiration in Heart Rate Variability (HRV) Analysis (2006)

Beat-to-beat changes in cardiac signals or heart rate variability (HRV) are controlled by the two branches of autonomic nervous system (ANS) in a very complex manner. Although traditional HRV (tHRV) analysis has shown to provide information on cardiac ANS control, it often fails to isolate the effect of two branches in HRV signals. This problem becomes more obvious especially at low respiratory rates since parasympathetic activity shifts into lower frequencies and overlaps the frequency interval where sympathetic region is defined. To investigate the effect of respiration in HRV analysis we have analyzed the data of 17 healthy subjects while they were performing normal breathing (NB) and deep breathing (DB). Data were analyzed and compared using both tHRV analysis and enhanced HRV (eHRV) analysis where we used respiration to locate the frequency interval of parasympathetic activity in HRV signal. eHRV analysis provided proper isolation and more accurate detection of parasympathetic and sympathetic control of the heart.
Effect of dl 3 n butylphthalide on memory disturbance induced by focal cerebral ischemia in rats (1997)

Effect of dl 3 n butylphthalide (NBP) on response for shuttle box was studied in rats subjected to middle cerebral artery occlusion (MCAO). Each rat was subjected to 20 trials per time for 4-5 times (one time every second day). A buzzer for 10 s was used as conditioning stimulus followed by a foot shock for 10 s as unconditioning stimulus . The error number of active avoidance response and the latencies of active avoidance and escape response were observed. NBP was given ig 15 min after MCAO. The experiment was carried out 24 h after MCAO. The result indicated that no change was found in the sham operation group before and after MCAO. However the number of the active avoidance responsewasdecreasedfrom16.7±2.9to6.5± 5.0, the latencies of active avoidance and escape response were prolonged by 4.2±1.6 and 4.1± 3.3 s after MCAO in vehicle group. The number of active avoidance response was significantly increased and the latencies of active avoidance and escape response were shortened markedly after receiving NBP 30 and 100 mg·kg 1 respectively. The results suggest that NBP has an ameliorative effect on memory disturbance induced by focal cerebral ischemia in rats.
Prolonged clinical benefit with metronomic chemotherapy in patients with metastatic breast cancer (2006)

The clinical efficacy and antiangiogenic effect of low-dose, metronomic administration of cyclophosphamide (CTX) and methotrexate (MTX) (CM) have been demonstrated. The authors report results and long-term follow-up for patients with metastatic breast carcinoma who obtained prolonged clinical benefit with CM. Prospectively collected data from two successive clinical trials were evaluated. From July 1997 to October 2003, patients with metastatic breast carcinoma were treated with low-dose oral chemotherapy (MTX 2.5 mg, twice daily on day 1 and day 2 or 4, and CTX 50 mg daily). Patients who achieved prolonged clinical benefit for a duration of 12 months or more (complete remission, partial remission or stabilization of disease) were considered for the analysis. Median follow-up was 23 months. A total of 153 patients were enrolled and are evaluable: Eastern Cooperative Oncology Group performance status 0-1 in 90 patients, two or more sites of metastatic disease in 97 patients, zero regimen for metastatic breast carcinoma in 48 patients. Among 153 patients, five demonstrated complete remission and 25 partial remission. The proportion of patients who achieved prolonged clinical benefit was 15.7% (95% confidence interval 9.9-21.4%). Median time to progression for patients with prolonged clinical benefit was 21 months (range 12-37+ months). One patient maintained complete remission 42 months after therapy discontinuation. At the multivariate analysis endocrine responsiveness and the achievement of an objective response significantly correlated with the achievement of prolonged clinical benefit. Metronomic chemotherapy can induce prolonged clinical benefit in metastatic breast cancer, supporting its role as an additional therapeutic tool in the treatment of patients with metastatic breast carcinoma.
Traditional architectural type simulation strategy to fulfil environmental sustainability Courtyard type as a model (2016)

In last decades, many architectural tendencies has appeared, that adapting sustainability, with various nominations, but with same or close meanings that refer to same concept. It's all dealing with principles, characteristics, dimensions, and elements of sustainable design, but it were lack to such a comprehensive framework treatment method. which resulting with abstrusely vision for the designer, globally and locally, to determine lineaments of design strategy, that depending on an environmental fundament, with sustainable impression. This abstrusity is the "research problem". This strategy may be strike from fundamental environmental design concept. There for, the research, suppose that, there is an ability to create general conceptual framework, can be used to specify or determine lineaments of design strategies, depending on an environmental idea, that able to give the project such a sustainability characteristic. According to this, the research aim specified as formulating general conceptual framework that having ability to assess projects or architectural designs, and specify or recognize adopted design strategy that strike from sustainable environmental fundament. To fulfill the aim, the research contains three terms. The first one focused on environment and sustainability, in order to understand accredited fundaments, which used to formulate sustainable environmental assessment and design systems, and to produce such a procedural definition for sustainable environmental design. Second term utilize results of former term to formulate a comprehensive theoretical framework, with primary terms and secondary indicators, which inserted in separated table to be implement in term three on selected project (modern courtyard house) to get results which discussed with its two sides, theoretical and practical, to put results and conclusions..
A detailed router based on simulated evolution (2003)

A representation scheme for a rip-up and rerouter is presented. The status of the routing region is represented as a four-dimensional matrix. Rip-up and re-route operations are emulated as matrix subtractions and additions, respectively. The quality of a routing result can be measured by performing a few simple matrix operations. A rip-up and reroute switch-box/channel router called SILK, using a simulated evolution technique, has been implemented on the basis of this representation scheme. Experimental results showed that SILK outperformed WEAVER, the most successful switch-box router to date, in both quality and speed aspects, for all the classical benchmarks available.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Constructions of Memoryless Crosstalk Avoidance Codes Via <inline-formula> <tex-math notation="TeX">${\cal C}$ </tex-math></inline-formula>-Transform (2013)

One of the main problems in deep submicrometer designs of high speed buses is the propagation delay due to the crosstalk effect. To alleviate the crosstalk effect, there are several types of crosstalk avoidance codes proposed in the literature. In this paper, we develop explicit constructions of two types of memoryless crosstalk avoidance codes: 1) forbidden overlap codes (FOCs) and 2) forbidden transition codes (FTCs). Our constructions for both FOCs and FTCs have the largest set of codewords. To the best of our knowledge, this is the first explicit construction of a FOC that has the largest set of codewords. Our approach is based on the C-transform developed for routing optical packets in optical queues. We show such an approach can also be used for constructing limited-weight no adjacent transition codes.
Multifocal pupillographic visual field testing in glaucoma (2009)

The method produced diagnostic accuracy approaching that of automated perimetry, but unlike perimetry provides standard errors for every point in each field as well as information on response delay and efferent defects. Only one pupil needs to function to measure both visual fields.
In-flight size classification of carbon nanotubes by gas phase electrophoresis (2005)

We demonstrate the use of gas phase electrophoresis to size classify CNTs grown in a continuous aerosol process. The separation process occurs at atmospheric pressure and involves electrostatic mobility separation which classifies fibres on the basis of equivalent projected surface area. This implies that one can, for diameter-controlled CNTs, obtain an on-the-fly determination of the CNT length distribution during CNT synthesis, or alternatively have a method for producing size separated CNTs. The method should be generic to any fibre based material.
The Structure Superposition Database (2003)

The need for new tools for investigating biological systems on a large scale is becoming acute, particularly with respect to computationally intensive analyses such as comparisons of many three-dimensional protein structures. Structure superposition is a valuable approach for understanding evolutionary relationships and for the prediction of function. But while available tools are adequate for generating and viewing superpositions of single pairs of protein structures, these tools are generally too cumbersome and time-consuming for examining multiple superpositions. To address this need, we have created the Structure Superposition Database (SSD) for accessing, viewing and understanding large sets of structure superposition data. The initial implementation of the SSD contains the results of pairwise, all-by-all superpositions of a representative set of 115 (beta/alpha)8 barrel structures (TIM barrels). Future plans call for extending the database to include representative structure superpositions for many additional folds. The SSD can be browsed with a user interface module developed as an extension to Chimera, an extensible molecular modeling program. Features of the user interface module facilitate viewing multiple superpositions together. The SSD interface module can be downloaded from http://ssd.rbvi.ucsf.edu.
Space–time mapping and tiling: a helpful combination (2004)

Abstract Tiling is a well‐known technique for sequential compiler optimization, as well as for automatic program parallelization. However, in the context of parallelization, tiling should not be considered as a stand‐alone technique, but should be applied after a dedicated parallelization phase, in our case after space–time mapping . We show how tiling can benefit from space–time mapping, and we derive an algorithm for computing tiles which can minimize the number of communication startups, taking the number of physically available processors into account. We also present how the use of a simple cost model reduces real execution time. Copyright © 2004 John Wiley & Sons, Ltd.
Effects of alveolar hypoxia on the pulmonary circulation and lung mechanics after cromolyn sodium and U-60,257 in lambs. (1992)

Because alveolar hypoxia (HYP) triggers pulmonary mast cell degranulation with elaboration of vasoactive mediators such as leukotrienes, we investigated the effects of aerosolized cromolyn sodium (CS), a mast cell stabilizing agent, and U-60,257(U) (a leukotriene blocker) on the circulation, lung mechanics and thromboxane (TXB2) levels in 11 lambs during acute exposure to HYP. Studies were performed in awake, chronically instrumented animals, once after placebo (saline) and again after CS (100 mg; n = 5) or U (90 mg; n = 6). Pulmonary arterial pressure increased 42% during HYP after saline, and 32% and 19% after CS and U, respectively. Pulmonary vascular resistance did not change during HYP after CS or U. Systemic arterial pressure was unchanged after saline and CS but decreased after U; systemic vascular resistance dropped after both CS and U. No changes were seen in tidal volume, lung compliance or airway resistance during HYP after saline or either drug, but minute ventilation increased during HYP in all studies. TXB2 increased during HYP after saline in both studies and was not altered by CS. In contrast, after U, TXB2 decreased. Thus, U more effectively blunted the pulmonary vascular response to HYP than CS and resulted in mild systemic hypotension. The drop in TXB2 after U suggests leukotriene-induced thromboxane synthesis contributes to regulation of pulmonary, and possibly, systemic vasoactivity.
SCID - a non-actuated robot for walls exploration (2002)

In this paper a control methodology applied to a passive mechanical system is described. The sliding climbing inspection device (SCID) has been designed to slide down over a ferromagnetic vertical surface, using two electromagnets. The on-board electronics and the control algorithm used allow the system to control its velocity and trajectory. The system was experimentally tested and a simplified mathematical model was computed.
Embryonic stem cell virus, a recombinant murine retrovirus with expression in embryonic stem cells. (1990)

The expression of Moloney murine leukemia virus and vectors derived from it is restricted in undifferentiated mouse embryonal carcinoma and embryonal stem (ES) cells. We have developed a retroviral vector, the murine embryonic stem cell virus (MESV), that is active in embryonal carcinoma and ES cells. MESV was derived from a retroviral mutant [PCC4-cell-passaged myeloproliferative sarcoma virus (PCMV)] expressed in embryonal carcinoma cells but not in ES cells. The enhancer region of PCMV was shown to be functional in both cell types, but sequences within the 5' untranslated region of PCMV were found to restrict viral expression in ES cells. Replacement of this region by related sequences obtained from the dl-587rev retrovirus results in MESV, a modified PCMV virus that confers G418 resistance to fibroblasts and ES cells with similar efficiencies. Expression of MESV in ES cells is mediated by transcriptional regulatory elements within the 5' long terminal repeat of the viral genome.
At Least One Class I Gene in Restriction Fragment Pattern-Y ( <i>Rfp-Y</i> ), the Second <i>MHC</i> Gene Cluster in the Chicken, Is Transcribed, Polymorphic, and Shows Divergent Specialization in Antigen Binding Region (2001)

MHC genes in the chicken are arranged into two genetically independent clusters located on the same chromosome. These are the classical B: system and restriction fragment pattern-Y (Rfp-Y), a second cluster of MHC genes identified recently through DNA hybridization. Because small numbers of MHC class I and class II genes are present in both B: and Rfp-Y, the two clusters might be the result of duplication of an entire chromosomal segment. We subcloned, sequenced, and analyzed the expression of two class I loci mapping to Rfp-Y to determine whether Rfp-Y should be considered either as a second, classical MHC or as a region containing specialized MHC-like genes, such as class Ib genes. The Rfp-Y genes are highly similar to each other (93%) and to classical class Ia genes (73% with chicken B: class I; 49% with HLA-A). One locus is disrupted and unexpressed. The other, YFV, is widely transcribed and polymorphic. Mature YFV protein associated with beta(2)m arrives on the surface of chicken B (RP9) lymphoma cells expressing YFV as an epitope-tagged transgene. Substitutions in the YFV Ag-binding region (ABR) occur at four of the eight highly conserved residues that are essential for binding of peptide-Ag in the class Ia molecules. Therefore, it is unlikely that Ag is bound in the YFV ABR in the manner typical of class Ia molecules. This ABR specialization indicates that even though YFV is polymorphic and widely transcribed, it is, in fact, a class Ib gene, and Rfp-Y is a region containing MHC genes of specialized function.
Anodic Oxide Films for Device Fabrication in Silicon (1964)

The preparation of phosphorus doped anodic oxide films on silicon is described. These oxide films can be used as phosphorus diffusion sources during heat treatment. The concentration and distribution of the phosphorus in the oxide film has been investigated by tracer techniques, the quality of the oxide film by electron microscopy. Oxide growth in the solutions and at the current densities investigated occurs preponderantly by cation migration. A novel method is described for measuring the amount of silicon converted into oxide per volt forming voltage. The density of the oxide can also be calculated by this method.