gebhart/patrepeval huggingface dataset:
A full-duplex wireless integrated transceiver for implant-to-air data communications (2015)

This paper presents a novel fully integrated full-duplex data transceiver to support bidirectional high-data rate neural interfaces (electrical stimulation and neural recording). The transmitter (TX) and the receiver (RX) are designed to share a single implantable antenna. The TX generates IR-UWB based on edge combining, and the RX uses a novel ISM-2.4-GHz narrow-band OOK receiver. Separation between the TX and RX path is implemented by: 1) properly shaping the transmitted pulse, so its spectrum falls between 3.1 and 7 GHz UWB subband, and 2) carefully filtering the spectrum of the received waveform directly in the receiver low-noise amplifier (LNA), to avoid using a circulator or a diplexer (found in most full duplex systems). The receiver is designed to support downlink telemetry of neural stimulation applications with a data rate as high as 100 Mbps within a power budget of 5 mW. The transmitter is designed to support uplink back telemetry of neural recording applications with a data rate of up to 500 Mbps for power consumption of 5.4 mW and 10.8 mW for OOK and BPSK modulations, respectively (10.8 pJ/b). Measurement results obtained with biological tissues confirm full functionality of the fabricated full duplex transceiver. The total size of the chip is 0.8 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> .
Efficient stimulated Raman scattering due to absence of second Stokes growth (1984)

Stimulated Raman scattering of a XeCl laser at 308 nm in a high-pressure H(2) cell shows high conversion into first Stokes (S1) because of an unexpected holdoff of the second Stokes (S2) component. Specifically, a photon efficiency of 88% is obtained into S1. Comparison with a plane-wave model indicates that a theory including a spatially nonuniform gain and higher-order mode generation may be necessary to understand the holdoff of the S2 growth.
Colon cleansing for diagnostic and surgical procedures: polyethylene glycol-electrolyte lavage solution. (1989)

Recent work has shown that polyethylene glycol-electrolyte lavage solutions provide adequate cleansing in preparation for colonoscopy, barium enema, intravenous pyelography, and colon surgery. It is safe and well tolerated by patients, and seems ideal for those with renal or cardiovascular disease who must undergo colon cleansing. We review the development of polyethylene glycol-electrolyte lavage solution and the clinical experience with various colon-cleansing preparations.
A PCR method for accurate assessment of trinucleotide repeat expansion in Huntington disease (1993)

Journal Article A PCR method for accurate assessment of trinucleotide repeat expansion in Huntington disease Get access Y.Paul Goldberg, Y.Paul Goldberg Department of Medical Genetics, University of British ColumbiaVancouver, BC V6T 1Z4, Canada Search for other works by this author on: Oxford Academic PubMed Google Scholar Susan E. Andrew, Susan E. Andrew Department of Medical Genetics, University of British ColumbiaVancouver, BC V6T 1Z4, Canada Search for other works by this author on: Oxford Academic PubMed Google Scholar Lorne A. Clarke, Lorne A. Clarke Department of Medical Genetics, University of British ColumbiaVancouver, BC V6T 1Z4, Canada Search for other works by this author on: Oxford Academic PubMed Google Scholar Michael R. Hayden Michael R. Hayden * Department of Medical Genetics, University of British ColumbiaVancouver, BC V6T 1Z4, Canada * To whom correspondence should be addressed Search for other works by this author on: Oxford Academic PubMed Google Scholar Human Molecular Genetics, Volume 2, Issue 6, June 1993, Pages 635–636, https://doi.org/10.1093/hmg/2.6.635 Published: 01 June 1993 Article history Received: 22 April 1993 Accepted: 22 April 1993 Published: 01 June 1993
Surface expression of a nonstructural antigen on influenza A virus-infected cells (1981)

Rabbit antiserum to the influenza A virus nonstructural protein, NS1, was used for indirect immunofluorescence studies of infected cells. Nonstructural antigens were detected on surfaces of P815 cells as early as 4 h after infection with A/WSN/40 virus. Adsorption of the serum with virion structural proteins did not affect the observed fluorescence, and a progressive increase in surface fluorescence at later times postinfection indicated that the surface antigen was newly synthesized during the replication cycle.
Microfluidic cartridge with integrated array of amorphous silicon photosensors for chemiluminescence detection of viral DNA (2016)

Portable and simple analytical devices based on microfluidics with chemiluminescence detection are particularly attractive for point-of-care applications, offering high detectability and specificity in a simple and miniaturized analytical format. Particularly relevant for infectious disease diagnosis is the ability to sensitively and specifically detect target nucleic acid sequences in biological fluids. To reach the goal of real-life applications for such devices, however, several technological challenges related to full device integration are still to be solved, one key aspect regarding on-chip integration of the chemiluminescence signal detection device. Nowadays, the most promising approach is on-chip integration of thin-film photosensors. We recently proposed a portable cartridge with microwells aligned with an array of hydrogenated amorphous silicon (a-Si:H) photosensors, reaching attomole level limits of detection for different chemiluminescence model reactions. Herein, we explore its applicability and performance for multiplex and quantitative detection of viral DNA. In particular, the cartridge was modified to accommodate microfluidic channels and, upon immobilization of three oligonucleotide probes in different positions along each channel, each specific for a genotype of Parvovirus B19, viral nucleic acid sequences were captured and detected. With this system, taking advantage of oligoprobes specificity, chemiluminescence detectability, and photosensor sensitivity, accurate quantification of target analytes down to 70 pmol L -1 was obtained for each B19 DNA genotype, with high specificity and multiplexing ability. Results confirm the good detection capabilities and assay applicability of the proposed system, prompting the development of innovative portable analytical devices with enhanced sensitivity and multiplexed capabilities.
Electronic structures and instabilities of ZrNCl and HfNCl: implications for superconductivity in the doped compounds (1999)

Amongst the many rules of thumb that prevail in the search for new superconductors is a belief that square nets of metal atoms are crucial to the achievement of high transition temperatures. The recent finding of superconductivity below 26 K in some intercalated β-HfNCl phases suggests that high transition temperatures might be achievable in compounds with triangular or graphite-like nets as well. Here we present key features of high level ab initio band structure calculations on the insulating ZrNCl and HfNCl parent compounds. Electron doping through intercalation has been modeled within a rigid-band framework. Features in the energy isosurfaces of the ‘doped’ compounds are examined for nesting instabilities of the kind that have been implicated in the superconducting properties of high-T c compounds with square nets. Despite very different electron counts, bonding patterns and atom topologies, it would seem that certain important aspects of the Fermi surfaces of the superconducting Zr(Hf)NCl phases are in many respects very similar to the Fermi surfaces of the cuprate high-T c superconductors.
Shape, F‐actin, and surface morphology changes during chemotactic peptide‐induced polarity in human neutrophils (1995)

These findings show the relation between reorganization of the microfilamentous cytoskeleton and modifications in cell shape and surface features during cell polarization induced after fMLP activation in neutrophils. This approach offers a powerful tool for further analysis of receptor distribution in polarized, motile neutrophils.
XA readout chip characteristics and CdZnTe spectral measurements (1999)

The authors report on the performance of a CdZnTe (CZT) array readout by an XA (X-ray imaging chip produced at the AMS foundry) application specific readout chip (ASIC). The array was designed and fabricated at NASA/Goddard Space Flight Center (GSFC) as a prototype for the Burst Arc-Second Imaging and Spectroscopy gamma-ray instrument. The XA ASIC was obtained from Integrated Detector and Electronics (IDE), in Norway. Performance characteristics and spectral data for /sup 241/Am are presented both at room temperature and at -20/spl deg/C. The measured noise (/spl sigma/) was 2.5 keV at 60 keV at room temperature. This paper represents a progress report on work with the XA ASIC and CZT detectors. Work is continuing and in particular, larger arrays are planned for future NASA missions.
Chromatin Specificity of Anti-Double-Stranded DNA Antibodies and a Role for Arg Residues in the Third Complementarity-Determining Region of the Heavy Chain (2003)

A spontaneous, autoreactive autoantibody called SN5-18 (IgG2b, kappa) binds to a complex of H2A/H2B/dsDNA in chromatin, but erroneously appears to bind dsDNA when the Ab is used in a form that is not highly purified. Because of this finding, we evaluated the antigenic specificity of a prototypic anti-dsDNA Ab, 3H9/Vkappa4, now used widely in transgenic studies of tolerance and autoimmunity. We found that the purified mAb 3H9/Vkappa4 binds chromatin and specifically a complex of H2A/H2B/dsDNA, but not dsDNA in solid phase or in solution. When used in the form of culture supernatant or as a standard protein G preparation, mAb 3H9/Vkappa4 appears to bind dsDNA, apparently due to nuclear proteins in the preparation that assemble on target DNA. Because of the reported role of V(H)CDR3 Arg residues in dsDNA binding and the near identity of the SN5-18 sequence to other dsDNA-specific Ab, we tested the contributions of two V(H)CDR3 Arg residues in SN5-18 to chromatin specificity. We found that both these Arg residues at positions 104 and 106 were required for detectable chromatin binding. These results indicate a role for V(H)CDR3 Arg residues in chromatin specificity of lupus-derived autoantibodies. Further, they provide an explanation for a possible discrepancy in the form of tolerance observed in different anti-DNA Ig transgene models.
A Brief Overview of VXLAN EVPN (2021)

The purpose of this paper is to provide network professionals with a common need to comprehend how to use VXLAN networks within their own organizations to release the entire potential of modern networking. Whilst interested network administrators shall acquire the most advantages from such content, the information contained within this research paper might be of use to each IT professional involved in network technologies. Aspects in this paper examine how VXLAN EVPN provides a solution to network challenges that have overwhelmed the entire industry for many years, and how to implement constructs that are usually observed in traditional networks thanks to this new technology. This research paper explores VXLAN EVPN, starting with an introductory stage, achieving a good understanding of terms and concepts as well as progressing via implementations through a single data center to several data centers. The following paper also refers design and the integration of Layer4-Layer7 network services, coexistence along with brownfield environments, operation, as well as maintain a VXLAN EVPN. At the conclusion of this paper, the reader will have a strong foundation of VXLAN EVPN and an understanding of real-world use instances that can be instantly used to help in the development of a strategy to effectively shift to the next-generation data center with this new technology.
ENHANCEMENT OF GERMINATION AND EMERGENCE OF CANOLA SEEDS BY DIFFERENT PRIMING TECHNIQUES (2004)

The present study was conducted to enhance the germination and\nemergence of canola (Brassica napus ) CV. Zafar-2000 seeds\nusing different priming treatments. For comparison with non-soaked\ncontrol, different priming techniques i.e. osmopriming with PEG-6000,\nhydropriming and matriconditioning with compost,jute mat and press mud\nof sugar mill for 24 hours were used. All priming treatments were\neffective in improving germination percentage as compared to control\nexcept SMP with press mud. The osmopriming and matriconditioning (jute\nmat) proved to be the best in reducing the time to 50% germination and\nmean germination time among all priming treatments. During emergence\ntest, both priming treatments i.e; osmopriming and matriconditioning\n(jute mat for 24 hours reduced the time to 50% emergence and mean\nemergence time. Maximum root and shoot lengths were recorded in\nhydroprimed seeds. Highest electrical conductivity was recorded for\ncontrol while lowest electrical conductivity was recorded in osmoprimed\nseeds. It is concluded that priming of seeds with PEG6000 and\nmatriconditioning (jute mat) are most effective in improving\ngermination and seedling emergence of canola seeds.
Ablation of Tumor Cells <i>In Vivo</i> by Direct Injection of HSV‐Thymidine Kinase Retroviral Vector and Ganciclovir Therapy (1999)

The introduction of therapeutic genes into proliferating tumor cells in vivo by direct intralesional injection of retroviral vectors can provide an effective and valuable approach for the treatment of a variety of solid tumor types. Efficient transduction of tumor cells in situ by direct injection was demonstrated using a retroviral vector containing the beta-galactosidase (beta-gal) gene. Ablation therapy in vivo was demonstrated using a retroviral vector containing the Herpes simplex virus thymidine kinase gene (HSV-TK) to deliver the TK gene into the murine colorectal tumor cell line CT26. Ablation of CT26 tumor cells in situ was achieved by directly injecting high-titer HSV-TK retroviral vector preparations into the site of tumor cell inoculation followed by intraperitoneal (i.p.) delivery of ganciclovir (GCV). This gene therapy strategy demonstrated a markedly lower rate of tumor progression, with several complete regressions, compared to animals in control groups. We also demonstrated that resistance to subsequent challenges with unmodified CT26 cells and an enhanced cellular immune response is associated with tumor regression in immunocompetent animals. Our results demonstrate the feasibility of direct in situ administration of HSV-TK retroviral vectors for the treatment of cancer and suggest that a cellular immune response may be elicited by this therapy.
Demonstration of nano-structures using wedge-molding process (2004)

A technique for nano-pattern generation and transfer, called "wedge molding" process is demonstrated. The technique utilizes anisotropic wet-chemical etching of crystalline InP or silicon wafer to obtain ultra-smooth V-grooves with nano-scale features (such as lines and dots) to create molds for a nano-imprinting process. High fidelity polymer materials, such as PDMS and Epoxy, were chosen to replicate the nano-features of groove bottoms. The technique has advantages of low cost, easy fabrication, high throughput, and high fidelity in generating nano-scale features such as wires and dots. Preliminary results indicate anisotropic wet-chemical etching could achieve smaller than 30 nm lateral size at the bottom of etched groove. High fidelity PDMS molds and epoxy molds can be replicated from the etched V-groove. AFM results demonstrated that around 100 nm wide line pattern could be transferred to nitride wafer with controlled RIE process.
THE OXIDATIVE AMMONOLYSIS OF ORGANIC COMPOUNDS (1965)

CONTENTS I. Introduction 657 II. Oxidative ammonolysis of aromatic hydrocarbons 657 III. Oxidative ammonolysis of cycloalkanes and cycloalkenes 660 IV. Oxidative ammonolysis of alkenes 660 V. Oxidative ammonolysis of alkylpyridines 661 VI. Some questions connected with the mechanism of oxidative ammonolysis of organic compounds 661
Ribozymes in the Age of Molecular Therapeutics (2004)

Ribozymes are RNA molecules capable of sequence-specific cleavage of other RNA molecules. Since the discovery of the first group I intron ribozyme in 1982, new classes of ribozymes, each with their own unique reaction, target site specifications, and potential applications, have been identified. These include hammerhead, hairpin, hepatitis delta, varkud satellite, groups I and II intron, and RNase P ribozymes, as well as the ribosome and spliceosome. Meanwhile, ribozyme engineering has enabled the in vitro selection of synthetic ribozymes with unique properties. This, along with advances in ribozyme delivery methods and expression systems, has led to an explosion in the potential therapeutic applications of ribozymes, whether for anti-cancer or anti-viral therapy, or for gene repair.
Grover Disease (Transient Acantholytic Dermatosis) (2009)

Abstract Grover disease, also known as transient acantholytic dermatosis, is a papulovesicular rash of the upper trunk, generally among older white males; it is usually pruritic but temporary. Grover disease is characterized by 4 different acantholytic histologic patterns, and it has been associated with numerous disorders, including hematologic malignancies. Follow-up and treatment are often difficult to evaluate secondary to the spontaneous remittance and occasional fluctuant course of the disease. Our objective will be to discuss the diagnostic considerations of Grover disease and focus on the postulated pathogenesis, including concurrent disorders and the role of the pathologist in examining skin biopsies of this nonhereditary vesicobullous disorder. Although recognized as a common condition, Grover disease's pathogenesis still remains unknown. Because Grover disease has been associated frequently with other dermatologic and nondermatologic skin conditions, inspection for other pathologic processes within the skin biopsy is essential to rule out other concomitant disorders, including hematopoietic malignancies.
Oxygen Reduction on Transition‐Metal Porphyrins in Acid Electrolyte I. Activity (1981)

Abstract The oxygen reduction characteristics of metalloporphyrins adsorbed at monolayer levels on a high surface area carbon, Norit BRX, have been studied in 8 N H 2 SO 4 and also in 6N KOH. In an acid, oxygen reduction activity is found to be correlated with the Me II /Me III redox potential. Most Co complexes have too high a redox potential, while too low a redox potential is observed for Fe, Ru, Os, Mn, and Cr. Ir porphyrins have the highest activity. In KOH, Ru porphyrins show the best performance. A heat treatment improves activity and stability strongly in an acid, but only mildly in an alkaline solution. A mechanism is proposed for oxygen reduction on transition metal chelates, both in acid and in alkaline solutions.
Reservoir Heating by Hot Fluid Injection (1959)

Published in Petroleum Transactions, AIME, Volume 216, 1959, pages 312–315. Abstract The injection of heat-bearing fluid may offer a wider application to secondary and tertiary recovery from conventional oil reservoirs than underground combustion since the process is more easily controlled and the reservoir requirements, in general, are less critical. In all cases, conduction heat losses to overburden and underburden will impose an economic limit upon the size of the area which can be swept out from any one injection point for any given set of conditions. The present report describes a method for estimating thermal invasion rates, cumulative heated area, and theoretical economic limits for sustained hot-fluid injection at a constant rate into an idealized reservoir. Full allowance is made for non-productive reservoir heat losses. Required solutions can be obtained directly from the numerical tables given here, as soon as all operating conditions are specified, without extensive mathematical manipulation on the part of the user. Introduction The injection of a heat-bearing fluid into a reservoir is frequently proposed as a means of secondary or tertiary oil production. This form of thermal recovery may offer a wider application to conventional oil reservoirs than underground combustion since the process is more easily controlled and the reservoir requirements, in general, are less critical. Because of its large gross heat capacity, steam appears to be the most efficient heat injection medium, although mixtures of steam and other gases, hot water, hot oil and hot non-condensable gases also have been employed. Whatever the nature of the injection medium, economic evaluation of such thermal recovery processes will depend upon thermal invasion rates, or rates of productive reservoir heating, at any given time after the start of heat injection. In all cases, conduction heat losses to overburden and underburden will impose an economic limit upon the size of the area which can be swept out from any one injection point, for a given set of reservoir conditions, at any given heat injection rate. The present report describes a method for estimating thermal invasion rates, cumulative heated area and theoretical economic limits for sustained heat injection at a constant rate into an idealized reservoir, making full allowance for non-productive reservoir heat losses. Required solutions can be obtained directly from the numerical tables given here, as soon as all operating conditions are specified, without extensive mathematical manipulation.
Design and optimization of sub harmonic mixer with harmonic rejection for direct-down conversion receivers (2011)

Frequency translation in a system is performed by a non-linear device known as a mixer. There are various topographies from simple single ended, single balanced mixers to more complicated double & triple balanced mixers that provide better isolation from the Local Oscillator (LO) and spurious. The most popular double-balanced mixer used in RFIC designs is the Gilbert Cell mixer. The design of this mixer with harmonic rejection is the subject of this paper. This paper presents a novel low power high linear sub-harmonic mixer for direct-down conversion receivers, which is proposed to improve the linearity and enhance the gain of the Mixer and also avoids the need for a discrete filter by attenuating the third and fifth harmonics using the harmonic rejection structure. Simulation results performed by Advanced Design System (ADS) shows a voltage conversion gain of 10.119 dB, an overall double side band noise figure of 6.219 dB, and IIP3 of 8.018 dBm from 2.8 V supply for a frequency of 2500 MHz.
[Post-mastectomy radiotherapy with different fractionated dose schemes in early breast cancer]. (2003)

With similar 5-year tumor-free survival rates by the conventional fractionation and hypofractionation, the scheme with 45 Gy/15 fractions/5 weeks has the advantage of giving less factions, which is suitable for a unit with limited radiation resources. The course of hypofractionation with 23 Gy/4 fractions/17 days is much shorter than conventional radiotherapy, which may benefit patients with higher risk of metastasis who need to undergo chemotherapy earlier. This study warrants further investigations.