gebhart/patrepeval huggingface dataset:
Robust Network Traffic Classification (2014)

As a fundamental tool for network management and security, traffic classification has attracted increasing attention in recent years. A significant challenge to the robustness of classification performance comes from zero-day applications previously unknown in traffic classification systems. In this paper, we propose a new scheme of Robust statistical Traffic Classification (RTC) by combining supervised and unsupervised machine learning techniques to meet this challenge. The proposed RTC scheme has the capability of identifying the traffic of zero-day applications as well as accurately discriminating predefined application classes. In addition, we develop a new method for automating the RTC scheme parameters optimization process. The empirical study on real-world traffic data confirms the effectiveness of the proposed scheme. When zero-day applications are present, the classification performance of the new scheme is significantly better than four state-of-the-art methods: random forest, correlation-based classification, semi-supervised clustering, and one-class SVM.
Diagnosis and management of thalassaemia (2012)

#### Summary points

Increasing global migration has resulted in wider dispersal of people at risk of hereditary anaemias. As a result, haemoglobinopathies are becoming increasingly prevalent in countries where these diseases are not endemic. The treatment of thalassaemia major and intermedia has traditionally depended on preventing undesirable outcomes of disease, using transfusion therapy along with iron chelation. The only cure for the disease is stem cell transplantation. However, this is a complicated procedure, with better outcomes when offered at young ages, which strengthens the desirability of screening newborns in high risk populations. Multidisciplinary management of thalassaemia is recommended by international guidelines. Antenatal prevention programmes consist of identifying and counselling couples who carry the relevant genes, and offering them different options to prevent having a child with thalassaemia. In this review we summarise diagnostic, treatment, and prevention options in thalassaemia for generalist readers.

#### Sources and selection criteria

We searched PubMed, the Cochrane Library, and Medline up to October 2011 and found several randomised controlled trials and cohort studies as well as international guidelines. We used the following search terms: thalassaemia major, thalassaemia intermedia, β thalassaemia, α thalassaemia, HbH disease, neonatal screening, iron overload, chelation therapies, deferoxamine, exjade, deferiprone, splenectomy, stem cell transplantation, hydroxyurea.

The thalassaemias are a group of recessively autosomal inherited conditions characterised by decreased or absence of synthesis of one of the two polypeptide …
Preparation of benzimidazole N-oxides by catalytic hydrogenation (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation of benzimidazole N-oxides by catalytic hydrogenationJohn W. Schulenberg and Sandra. CornrichCite this: J. Chem. Eng. Data 1968, 13, 4, 574–575Publication Date (Print):October 1, 1968Publication History Published online1 May 2002Published inissue 1 October 1968https://pubs.acs.org/doi/10.1021/je60039a044https://doi.org/10.1021/je60039a044research-articleACS PublicationsRequest reuse permissionsArticle Views204Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Source-channel coding for algebraic multiterminal binning (2005)

This paper addresses practical code design problems for multiterminal communication networks. The basic element of a multiterminal network code is the binning scheme. We aim to develop a unified practical code design paradigm for related problems in multiterminal networks based on source-channel coding for algebraic binning. First, a framework based on Slepian-Wolf coded quantization is highlighted for Wyner-Ziv coding and multiterminal source coding (e.g., the CEO problem). Then, a nested turbo scheme is proposed for Costa coding by exploiting the duality between Costa coding and Wyner-Ziv coding.
Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation. (1993)

We used specific antisera and immunohistochemical methods to investigate the subcellular localization and expression of Bcr, Abl, and Bcr-Abl proteins in leukemic cell lines and in fresh human leukemic and normal samples at various stages of myeloid differentiation. Earlier studies of the subcellular localization of transfected murine type IV c-Abl protein in fibroblasts have shown that this molecule resides largely in the nucleus, whereas transforming deletion variants are localized exclusively in the cytoplasm. Here, we demonstrate that the murine type IV c-Abl protein is also found in the nucleus when overexpressed in a mouse hematopoietic cell line. However, in both normal and leukemic human hematopoietic cells, c-Abl is discerned predominantly in the cytoplasm, with nuclear staining present, albeit at a lower level. In contrast, normal endogenous Bcr protein, as well as the aberrant p210BCR-ABL and p190BCR-ABL proteins consistently localize to the cytoplasm in both cell lines and fresh cells. The results with p210BCR-ABL were confirmed in a unique Ph1-positive chronic myelogenous leukemia (CML) cell line, KBM5, which lacks the normal chromosome 9 and hence the normal c-Abl product. Because the p210BCR-ABL protein appears cytoplasmic in both chronic phase and blast crisis CML cells, as does the p190BCR-ABL in Ph1-positive acute leukemia, a change in subcellular location of Bcr-Abl proteins between cytoplasm and nucleus cannot explain the different spectrum of leukemias associated with p210 and p190, nor the transition from the chronic to the acute leukemia phenotype seen in CML. Further analysis of fresh CML and normal hematopoietic bone marrow cells reveals that p210BCR-ABL, as well as the normal Bcr and Abl proteins, are expressed primarily in the early stages of myeloid maturation, and that levels of expression are reduced significantly as the cells mature to polymorphonuclear leukocytes. Similarly, a decrease in Bcr and Abl levels occurs in HL-60 cells induced by DMSO to undergo granulocytic differentiation. The action of p210BCR-ABL and its normal counterparts may, therefore, take place during the earlier stages of myeloid development.
Secure and invisible data hiding in 2-color images (2002)

In an earlier paper, we propose a steganography scheme for hiding a piece of critical information in a host binary image. That scheme ensures that in each m/spl times/n image block of the host image, as many as [log/sub 2/(mn+1)] bits can be hidden in the block by changing at most 2 bits in the block. As a sequel of that work, in this paper we propose a revised scheme that can maintain higher quality of the host image by sacrificing some data hiding space. The new scheme can still offer a good data hiding ratio. It ensures that for any bit that is modified in the host image, the bit is adjacent to another bit which has a value equal to the former's new value. Thus, the hiding effect is quite invisible.
Intracellular inclusion bodies in 14 patients with B cell lymphoproliferative disorders. (1984)

Two types of intracytoplasmic inclusion were detected by immunofluorescence microscopy in 12 patients with chronic lymphocytic leukaemia and two patients with a leukaemic phase of well differentiated lymphocytic lymphoma. Further analysis with light- and electron microscopy, showed that most inclusion bodies were rod-like crystalline structures. However, in three patients they consisted of amorphous vesicular precipitates. Immunological studies revealed the presence of immunoglobulins of the same class and type at the cell surface as well as in the inclusion bodies. The monoclonal immunoglobulins were all of lambda type except in two cases. The origin of immunoglobulin inclusion bodies in B cell malignancies is discussed in relation to published data and our own observation in one patient followed during treatment.
A Quantum Dot Array for Enhanced Tricolor Liquid-Crystal Display (2017)

In the traditional liquid crystal display, at least two-thirds of the energy is wasted by tricolor separation color filter array due to its blocking working principle. In this paper, a well arrangement quantum dots (QD) array, which is excited by blue back light, was fabricated to spatially separate the red-green-blue (RGB) color. This QD array is further placed onto traditional color filter array, by matching the corresponding color filter pixel, in order to eliminate the blue light cross talk. In this case, the energy efficiency of this QD active color filter array no longer depends on its geometric arrangement and absorption properties, but depends on the quantum yield of QDs. Furthermore, 90% Adobe RGB color gamut can be achieved. One advantage of our fabrication method is synthesizing the QDs array onto the substrate directly, without the requirement of dissolving the QDs into other media. This technique may provide a new method to obtain higher color separation efficiency in liquid crystal display (LCD) than the traditional color filter matrix by enhancing the quantum yield of QDs.
Effects of substrate curvature on the adsorption of poly(3-hexylthiophene) on single-walled carbon nanotubes (2006)

A detailed study of poly(alkylthiophene) self-assembly and organization on single-walled carbon nanotubes (SWNTs) is presented. Monolayers of regioregular poly(3-hexyl thiophene) (rrP3HT) adsorbed on SWNTs have been imaged by using scanning tunneling microscopy. Our results show that the rrP3HT interchain distance is greater for rrP3HT monolayers adsorbed onto the curved surfaces of SWNTs than on the flat surfaces of highly ordered pyrolytic graphite samples. Comparisons between the native polymer deposited on graphite and the composite structure confirmed that the presence of carbon nanotubes in rrP3HT produces a new material with a high degree of order at the molecular level.
Non-invasive blood pressure measurement in Yucatan miniature swine using tail cuff sphygmomanometry. (1985)

A relatively new non-invasive method using a photo-electric flow sensor in non-heated animals, was evaluated for its accuracy in measuring systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean arterial pressure (MAP) in 40-90 Kg normotensive and hypertensive Yucatan miniature swine. Directly measured SBP, DBP and electronically averaged MAP were recorded from chronic arterial catheters simultaneously with indirect pressures, cuff pressure and tail blood flow under various conditions. In all of the tests tail cuff SBP estimation averaged within 5% of directly measured SBP. The correlation of the two methods was significant (r = .95, P less than 0.01). Over a 60 to 202 mmHg range of blood pressure induced pharmacologically or due to DOCA hypertension, the tail cuff SBP was within 4-10% of directly measured SBP. The tail cuff method was also used to determine DBP and MAP. DBP determined from the tail cuff record was found consistently to underestimate the direct measured DBP by approximately 17%. The two methods were correlated (r = .87 P less than 0.01). The measured tail cuff MAP generally underestimated the direct MAP by approximately 5%. The correlation of directly measured MAP and tail cuff methods was significant (r = .72, P less than 0.01). These results indicated that this system may be used to accurately assess blood pressure in miniature swine.
Chemical vapor deposition growth of a periodic array of single-layer MoS <sub>2</sub> islands via lithographic patterning of an SiO <sub>2</sub> /Si substrate (2015)

The growth of micron-scale single-layer MoS2 islands is seeded and distributed at high fidelity by means of a regular array of micron-scale holes that extend through the oxide layer of a 300 nm SiO2/Si substrate. Low coverages exhibit individual sub-micron MoS2 islands directly adjacent to the seed positions. At moderate coverage the seed holes are encircled by merged MoS2 islands, whose overall shape and internal grain boundaries reveal coalescence out of several initial crystallites. Seeded islands are strictly monolayer in height, non-overlapping and they offer high photoluminescence as well as conventional Raman signatures.
Some Nitrogen-Containing Ferrocene Derivatives (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSome Nitrogen-Containing Ferrocene DerivativesEDWARD M. ACTON and ROBERT M. SILVERSTEINCite this: J. Org. Chem. 1959, 24, 10, 1487–1490Publication Date (Print):October 1, 1959Publication History Published online1 May 2002Published inissue 1 October 1959https://pubs.acs.org/doi/10.1021/jo01092a024https://doi.org/10.1021/jo01092a024research-articleACS PublicationsRequest reuse permissionsArticle Views713Altmetric-Citations46LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Ras Target AF-6 Interacts with ZO-1 and Serves as a Peripheral Component of Tight Junctions in Epithelial Cells (1997)

The dynamic rearrangement of cell-cell junctions such as tight junctions and adherens junctions is a critical step in various cellular processes, including establishment of epithelial cell polarity and developmental patterning. Tight junctions are mediated by molecules such as occludin and its associated ZO-1 and ZO-2, and adherens junctions are mediated by adhesion molecules such as cadherin and its associated catenins. The transformation of epithelial cells by activated Ras results in the perturbation of cell-cell contacts. We previously identified the ALL-1 fusion partner from chromosome 6 (AF-6) as a Ras target. AF-6 has the PDZ domain, which is thought to localize AF-6 at the specialized sites of plasma membranes such as cell-cell contact sites. We investigated roles of Ras and AF-6 in the regulation of cell-cell contacts and found that AF-6 accumulated at the cell-cell contact sites of polarized MDCKII epithelial cells and had a distribution similar to that of ZO-1 but somewhat different from those of catenins. Immunoelectron microscopy revealed a close association between AF-6 and ZO-1 at the tight junctions of MDCKII cells. Native and recombinant AF-6 interacted with ZO-1 in vitro. ZO-1 interacted with the Ras-binding domain of AF-6, and this interaction was inhibited by activated Ras. AF-6 accumulated with ZO-1 at the cell-cell contact sites in cells lacking tight junctions such as Rat1 fibroblasts and PC12 rat pheochromocytoma cells. The overexpression of activated Ras in Rat1 cells resulted in the perturbation of cell-cell contacts, followed by a decrease of the accumulation of AF-6 and ZO-1 at the cell surface. These results indicate that AF-6 serves as one of the peripheral components of tight junctions in epithelial cells and cell-cell adhesions in nonepithelial cells, and that AF-6 may participate in the regulation of cell-cell contacts, including tight junctions, via direct interaction with ZO-1 downstream of Ras.
A Fast Settling Low Dropout Linear Regulator with Single Miller Compensation Capacitor (2005)

A 1.8-V, 150-mA fast settling low dropout linear regulator (LDO) with single Miller compensation capacitor is presented. By utilizing the digital-controlled dynamic bias circuit to track the output current, the proposed LDO provides fast settling time for the output capacitors with low and high equivalent series resistance (ESR). The proposed LDO has been fabricated in a 0.35-um 2P4M CMOS technology, and the active chip area is 480 um times675 um. The measurement results show the settling time of 4us can be achieved with 0.5% error for full load-current changes for both multilayer ceramic and electrolytic 1-uF output capacitors. Furthermore, the line and load regulations are 0.127%N and 40ppm/mA, respectively. The dropout voltage is 190mV in 150mA output current. The measured quiescent current is 45uA in 5V supply voltage without output current
Anti-oncogenic and pro-differentiation effects of clorgyline, a monoamine oxidase A inhibitor, on high grade prostate cancer cells (2009)

Our results suggest that inhibitors of MAO-A, already in clinical use to treat depression, may have potential application as therapeutic PCa drugs by inhibiting oncogenic pathway activity and promoting differentiation.
Real-time parallel remote rendering for mobile devices using graphics processing units (2010)

Demand for 3D visualization is increasing in mobile devices as users have come to expect more realistic immersive experiences. However, limited networking and computing resources on mobile devices remain challenges. A solution is to have a proxy-based framework that offloads the burden of rendering computation from mobile devices to more powerful servers. We present the implementation of a framework for parallel remote rendering using commodity Graphics Processing Units (GPUs) in the proxy servers. Experiments show that this framework substantially improves the performance of rendering computation of 3D video.
Sleep disturbances in depression and the effects of antidepressants (2005)

Depressed patients often report sleep problems, which usually include difficulties with initiation and maintenance of sleep, as well as poor subjective quality of sleep. Such reports are confirmed by objective analysis of depressed patients' sleep through polysomnography, although there is no exact correspondence between subjective and objective measurements. In the present paper, we discuss some methodological problems related to the subjective estimates of sleep. Further, we review the differential effects of the various classes of antidepressants on subjective sleep parameters, as well as on sleep onset latency, continuity of sleep, sleep efficiency and rapid eye movement (REM) sleep verified with sleep recordings. Finally, we discuss the attempts to use these and other indices, such as delta sleep ratio (DSR), as signposts of the course of the illness, and predictors of response to treatment.
Formation of multilayers by self-assembly (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFormation of multilayers by self-assemblyNolan Tillman, Abraham Ulman, and Thomas L. PennerCite this: Langmuir 1989, 5, 1, 101–111Publication Date (Print):January 1, 1989Publication History Published online1 May 2002Published inissue 1 January 1989https://pubs.acs.org/doi/10.1021/la00085a019https://doi.org/10.1021/la00085a019research-articleACS PublicationsRequest reuse permissionsArticle Views946Altmetric-Citations187LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Low noise perpendicular magnetic recording media for deep submicron track width recording (2000)

Noise reduction in double-layered perpendicular recording media with a thick soft magnetic backlayer was studied. Although the medium noise was increased with the backlayer, the noise for quaternary alloy films could be substantially reduced by introducing a certain intermediate layer between the alloy layer and the backlayer. The double-layered medium obtained exhibited a waveform with sharp transitions as well as a low noise property when recorded with a single pole head. The recording performances suggested the potential of the medium for a high areal density recording around 50 Gbit/in/sup 2/.
Research on PMD mitigation by using distributed fast polarization scrambling and FEC (2010)

Polarization mode dispersion (PMD) is one of the major obstacles in high-speed (above 100 Gbits rate) and long-haul optical communication system. In order to meet the requirements of high-sped optical communication quality, some PMD compensation and mitigation schemes had been developed. Forward error correction (FEC) is useful to increasing the system margin. The combination of distributed fast polarization scrambler (D-FPS) and FEC is an effective method to improving the optical system's PMD tolerance. The fundamental reason is that D-FPS can accelerate the redistribution of the link PMD to enable FEC to be more effective during the periods that would otherwise have PMD outages. Another advantage of this scheme is that it can mitigate the influence of PMD in multichannel system without feedback control and compensation based on each channel. The principle and performance of scrambling is introduced in this paper and the fundamental idea of improving PMD mitigation by using D-FPS combined with FEC is proposed. Some key factors such as scrambling speed and the number of scrambler which affecting the performance of this scheme are also introduced. Finally, proposing an assumption that the impact for system performance caused by the style of FPSs is distributed along the fiber link, and the mathematical estimation model is established. The combination of D-FPS and FEC would be a promising approach for performance improvement in ultra-high-speed optical communication system.