gebhart/patrepeval huggingface dataset:
Macrocycles of <scp>D</scp>‐ and <scp>L</scp>‐Proline Residues (1982)

Abstract The complete manuscript of this communication appears in: Angew. Chem. Suppl. 1982 , 533. DOI: 10.1002/anie.198205330
Polymer Injection to Rejuvenate a Supermature Oil Field, Polymer Pilot Results, 8 TH Reservoir, Austria (2016)

Abstract The 8 TH reservoir is a "supermature" field which has been in production for more than 65 years. It was waterflooded for more than 50 years resulting in a current water cut of 96 %. The field contains medium viscous oil (in-situ viscosity 19 cP) and hence was considered for polymer injection despite the high water cut which was suggested by some authors to be challenging for polymer injection. An inverted five spot unconfined polymer injection pilot was performed to reduce the subsurface uncertainties, determine if polymer flooding could lead to incremental oil in "supermature" fields, improve the operating and monitoring capabilities and improve the economic model for full-field implementation. The results of the pilot show that an increase in 5- 10 % of the recovery factor can be achieved in the pilot area. The reasons for incremental oil production by polymer injection in this "supermature" field are acceleration along high permeable flow paths but more importantly substantial flow diversion in this heterogeneous reservoir. In the pilot area, the highest oil production since 1978 was achieved. The main uncertainties related to surface handling of the polymer solution prior to injection, injectivity and incremental oil recovery could be reduced by monitoring of various parameters. In particular tracers and molecular weight distribution of polymers were measured to improve the understanding of the polymer solution effects on reservoir performance. In addition, numerical simulations concerning injectivity and reservoir performance were performed to further improve the understanding of the processes and be able to optimize the operations. The simulations included polymer solution injection induced fractures as well as geological, reservoir fluid/relative permeability and polymer solution property uncertainties and allowed forecasting under uncertainty. The cost structure of the polymer pilot was used to evaluate full-field economics taking learning curves, upscaling and costs optimisations into account.
Optical imaging with scanning MEMS mirror - A single photodetector approach (2009)

This paper describes an optical system for low-complexity optical image acquisition based on a single scanning MEMS mirror and a single photodetector. The overall aim of the research is to investigate techniques for image acquisition at electromagnetic wavelengths where the cost and/or technical maturity of detector arrays pose a limitation. In contrast to similar systems built using a digital micromirror device (DMD), the present configuration has advantages of lower cost and potential applicability across a wide spectrum, ranging from visible to Terahertz frequencies. In the present arrangement, light at visible wavelengths from the object passes through a telescope and falls onto a small, scanning MEMS micromirror. The entire image of the object is projected onto the mirror surface and reflected towards a single photodetector with a pinhole at its entrance. Similarly to conventional scanning, by finely changing the tilt-angle of the mirror, the detector sees different areas of the projected image, thereby building up an image pixel-by-pixel. Resolution is increased by allowing for an overlap between neighbouring scanned areas. Iterative bilinear interpolation and wavelet denoising are employed to enhance image quality.
Design process of high‐frequency inductor with multiple air‐gaps in the dimensional limitation (2021)

Abstract To find the optimal magnetic components designing process within the dimensional limitation, different inductor arrangements are developed. Different combinations of air‐gaps and material arrangements are used within the limited bobbin space to improve the saturation current capacity within the already set dimension. In this study, the mechanism requirement set at 1 U height is the limitation. There are two center‐pole material cores, and air‐gap distribution arrangement in the magnetic components. The saturation current value, magnetic flux density, flux fringing, and power loss of inductors are investigated with simulation, equation calculation and actual circuit measurement. The magnetic distribution affects the inductor performance because of the different relative permeability values, skin effect, proximity effect, and fringing effect. This research uses equations to find the magnetic flux density and the fringing magnetic flux, and uses Comsol Multiphysics® software to simulate the magnetic field. A 500 W boost power factor corrections (PFC) converter topology is used as an example experiment to compare and verify the inductors selected with proposed design methodology. Finally, the most appropriate core is chosen to implement the two‐stage AC/DC power supply products to improve the power supply performance.
Synthesis of phenolic esters with potential long-lasting insect-repellent properties (1968)

The synthesis of undecanoic acid esters of resorcinol, 4-chlororesorcinol, hexachlorophene, o-chlorophenol, and p-chlorophenol is described. The compounds were designed to provide, potentially, perdurable insect-repellent activity. When the synthesis of esters of resorcinol and 4-chlororesorcinol was attempted with undecanoic acid, under acid catalysis, principally ketones and ketoesters were isolated. The originally sought esters were obtained, however, by the reaction of the phenols with undecanoyl chloride in the presence of pyridine. The infrared, nuclear magnetic resonance, and mass spectra of the compounds are discussed.
ChemInform Abstract: Bulk High Temperature Superconductors for Magnet Applications (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Properties of a thermotropic liquid crystalline polymer blended with different thermoplastics (1992)

Abstract Thermal, rheological, morphological, and mechanical properties of a thermotropic liquid crystalline polymer, TLCP (copolyester Vectra A‐950 from Hoechst), blended with a polycarbonate (PC), a polyethylene glycol terephthalate (PETG), and a blend of PC and PETG (20/80) are presented and discussed. Important supercooling effects are observed for the TLCP. For the blends the glass transition temperature of the matrix is shown to decrease slightly, suggesting partial miscibility of the components. A finer dispersion is observed for the TLCP/PC blends, at least for TLCP concentrations lower than 20%, for which the mechanical properties are quite good. For higher TLCP concentrations, as well as for the other two matrices, the mechanical properties follow more or less the mixing rule, and the morphology of the blends suggests poor adhesion. We were unable to obtain fibrillar structures by extruding the blends through a capillary rheometer; in the TLCP/PC blends, the TLCP domains were too small, and for the other blends the extrudates had not enough melt strength.
Heritable components of the human fecal microbiome are associated with visceral fat (2016)

Our results provide novel insights into the role of the fecal microbiota in cardio-metabolic disease with clear potential for prevention and novel therapies.
Research on the Relationship between Internal Marketing and Medical Personnel's Turnover Intension in the Situation of a Dangerous Outbreak of Illness Like SARS.-A Regional Hospital for Example (2006)

Background and Purpose: The SARS outbreak caused tremendous fear and anxiety in the general public and particularly among patients and hospital staff in Taiwan. Many healthcare personnel quit their jobs or left work temporarily due to the SARS outbreak. The purpose of this study was to examine the relationship between the internal marketing identification when SARS outbreak and turnover intention after SARS outbreak among healthcare staff in a hospital in central Taiwan.
Methods: Medical personnel from a hospital in central Taiwan who held staff positions before the time of the first documented possible SARS case (March 8, 2003) were included. The study sample included a total of 510 workers. A questionnaire was completed by 296 of these subjects, resulting in a completion rate of 58%.
Results: During the SARS outbreak, higher identification with internal marketing was associated with lower turnover intention after the SARS outbreak (negative correlation). Factors related to turnover intention after SARS were as follows: internal communication, official rank: nurse, personal conditions, and family opposition to work.
Conclusions: The internal communication and personal conditions of internal marketing were significant predictive factors of turnover intention after the SARS outbreak. These findings suggest to give first priority to use the two dimensions (internal communication and personal conditions) to decrease the turnover intention when the hospital to face emergencies such as SARS in the future.
SketchStory: Telling More Engaging Stories with Data through Freeform Sketching (2013)

Presenting and communicating insights to an audience-telling a story-is one of the main goals of data exploration. Even though visualization as a storytelling medium has recently begun to gain attention, storytelling is still underexplored in information visualization and little research has been done to help people tell their stories with data. To create a new, more engaging form of storytelling with data, we leverage and extend the narrative storytelling attributes of whiteboard animation with pen and touch interactions. We present SketchStory, a data-enabled digital whiteboard that facilitates the creation of personalized and expressive data charts quickly and easily. SketchStory recognizes a small set of sketch gestures for chart invocation, and automatically completes charts by synthesizing the visuals from the presenter-provided example icon and binding them to the underlying data. Furthermore, SketchStory allows the presenter to move and resize the completed data charts with touch, and filter the underlying data to facilitate interactive exploration. We conducted a controlled experiment for both audiences and presenters to compare SketchStory with a traditional presentation system, Microsoft PowerPoint. Results show that the audience is more engaged by presentations done with SketchStory than PowerPoint. Eighteen out of 24 audience participants preferred SketchStory to PowerPoint. Four out of five presenter participants also favored SketchStory despite the extra effort required for presentation.
A microfiber scaffold-based 3D<i>in vitro</i>human neuronal culture model of Alzheimer's disease (2020)

Increasing evidence indicates superiority of three-dimensional (3D) in vitro cell culture systems over conventional two-dimensional (2D) monolayer cultures in mimicking native in vivo microenvironments. Tissue-engineered 3D culture models combined with stem cell technologies have advanced Alzheimer's disease (AD) pathogenesis studies. However, existing 3D neuronal models of AD overexpress mutant genes or have heterogeneities in composition, biological properties and cell differentiation stages. Here, we encapsulate patient induced pluripotent stem cell (iPSC) derived neural progenitor cells (NPC) in poly(lactic-co-glycolic acid) (PLGA) microtopographic scaffolds fabricated via wet electrospinning to develop a novel 3D culture model of AD. First, we enhanced cellular infiltration and distribution inside the scaffold by optimizing various process parameters such as fiber diameter, pore size, porosity and hydrophilicity. Next, we compared key neural stem cell features including viability, proliferation and differentiation in 3D culture with 2D monolayer controls. The 3D microfibrous substrate reduces cell proliferation and significantly accelerates neuronal differentiation within seven days of culture. Furthermore, 3D culture spontaneously enhanced pathogenic amyloid-beta 42 (Aβ42) and phospho-tau levels in differentiated neurons carrying familial AD (FAD) mutations, compared with age-matched healthy controls. Overall, our tunable scaffold-based 3D neuronal culture platform serves as a suitable in vitro model that robustly recapitulates and accelerates the pathogenic characteristics of FAD-iPSC derived neurons.
A Comparative Experimental and Theoretical Study between Heteroarm Star and Diblock Copolymers in the Microphase Separated State (2000)

A pronounced difference in the behavior of heteroarm star copolymers from the conventional diblock copolymers is analyzed theoretically and experimentally on the example of symmetric polystyrene-poly(2-vinylpyridine) (PS6P2VP6) star block copolymer melts. Microphase separation of PS6P2VP6 stars with volume fraction of PS varying from 0.30 to 0.75 is studied using transmission electron microscopy (TEM). The observed (lamellar, cylindrical and undefined “bicontinuous-like”) structures often turned out to be different from that expected for the corresponding diblock copolymers. The dependence of the long period of lamellar structures of heteroarm star block copolymers on block length is found to deviate in a systematic way from N2/3 law (known for diblock copolymers), especially for the stars of high functionality. The theoretical model proposed to describe an extra-stretching of star block copolymers near the lamellar interface is found to be successful in prediction of block length and star functionality dependence of the lamellar period as it agrees remarkably well with the present and other available experimental data for both symmetric and asymmetric heteroarm star block copolymers.
Mathematical models of hysteresis (1989)

This report discusses the Preisach model and Bean-London model of magnetic field hysteresis. (LSP)
Interventions for bullous pemphigoid (2010)

Very potent topical steroids are effective and safe treatments for BP, but their use in extensive disease may be limited by side-effects and practical factors. Milder regimens (using lower doses of steroids) are safe and effective in moderate BP. Starting doses of prednisolone greater than 0.75 mg/kg/day do not give additional benefit, lower doses may be adequate to control disease and reduce the incidence and severity of adverse reactions. The effectiveness of adding plasma exchange, azathioprine or mycophenolate mofetil to corticosteroids, and combination treatment with tetracycline and nicotinamide needs further investigation.
By name, by nature: the Oasis Cafe (2009)

Every hospital has a cafe; most of us will have used one to wait for, or recover from, some ordeal. Those who know the Oasis say that this is a hospital cafe with a difference: it doesn't feel like it is in a hospital. They speak of the welcoming, peaceful atmosphere, the high quality of its fare and ambience, and the way it generates enterprise and opportunity for people with past or present mental health problems. In this article we want to share how the cafe came about, what people say about it and what we think the future holds.
Procedure and Methods for Implementing a Process-oriented Quality Management System (2019)

Process-oriented Quality Management (PQM) is a helpful tool for meeting customer requirements, but also specific standard requirements. The global competition, steadily increasing competitive pressure and higher customer expectations make it essential for a company to deal intensively with this topic. This paper identifies, due to a qualitative and quantitative research approach through problem-centered interviews and questionnaires, a general procedure and possible methods for the implementation of a process-oriented quality management system with a view on a subsequent certification in an organization. After a description of the practical procedure for the iden-tification, analysis and documentation of existing processes in an exemplary company, the findings are summa-rized and an outlook on further processes and future possibilities for improvement will be offered.
Vitamin B6 Prevents Endothelial Dysfunction, Insulin Resistance, and Hepatic Lipid Accumulation in<i>Apoe</i><sup>−/−</sup>Mice Fed with High-Fat Diet (2015)

Backgrounds. VitB6 deficiency has been associated with a number of adverse health effects. However, the effects of VitB6 in metabolic syndrome are poorly understood. Methods. VitB6 (50 mg/kg/day) was given to Apoe (-/-) mice with hkdigh-fat diet (HFD) for 8 weeks. Endothelial dysfunction, insulin resistance, and hepatic lipid contents were determined. Results. VitB6 administration remarkably increased acetylcholine-induced endothelium-dependent relaxation and decreased random blood glucose level in Apoe (-/-) mice fed with HFD. In addition, VitB6 improved the tolerance of glucose and insulin, normalized the histopathology of liver, and reduced hepatic lipid accumulation but did not affect the liver functions. Clinical and biochemical analysis indicated that the levels of VitB6 were decreased in patients with fatty liver. Conclusions. Vitamin B6 prevents endothelial dysfunction, insulin resistance, and hepatic lipid accumulation in Apoe (-/-) mice fed with HFD. Supplementation of VitB6 should be considered to prevent metabolic syndrome.
Solubility products of magnesium ammonium and magnesium potassium phosphates (1963)

The first page of this article is displayed as the abstract.
Coil-Tubing Milling/Underreaming of Barium Sulphate Scale and Scale Control in the Forties Field (1991)

ABSTRACT Barium sulphate scale formation can occur readily in the wellbores of the Forties field when produced water containing a high barium ion concentration mixes with injection sea water of a high sulphate ion concentration. Typically scale formation begins with the onset of sea water breakthrough into a wellbore and can lead to very rapid production declines. To date, seven coiled tubing scale millouts have been performed on producing wells in the Forties field. These operations have resulted in a combined 39,000 bbl/d (6201 m3/d) increase in production. This paper describes the mechanism of barium sulphate scale formation and the mechanical removal of the scale using coiled tubing with downhole motors, bits and underreamers. A scale millout case history is presented and the successful prevention of scale formation via scale inhibitor treatments is discussed.
DNA Damage Photoinduced by Titanium Dioxide in the Presence of Anionic Vesicles under UV Illumination: Influence of Sodium Chloride Concentration (2007)

The DNA damage caused by TiO2 under in vitro conditions by UV-A exposure in the presence of anionic vesicles of Aerosol OT (AOT) was investigated. The supercoiled form (S) in DNA plasmids was converted to the linear form (L) via the relaxed form (R). The DNA damage was slower in the presence of AOT vesicles prepared in aqueous NaCl solution. Moreover, the presence of AOT vesicles in solution after 6 h of UV irradiation was confirmed with an optical microscope. Probably, a fraction of the DNA was protected by random trapping during sonication. However, the addition of NaCl needed for the vesicle formation can decrease the TiO2 activity. On the other hand, in the absence of vesicles the NaCl concentration led to a profound influence on the adsorption of DNA onto the TiO2 surface. During UV irradiation, the degradation rate of DNA increased with increasing the salt concentration. Solutions containing vesicles were prepared at various NaCl concentrations between 10 mM and 75 mM. Consequently, the salt concentration had no significant effect on the DNA damage. The presence of NaCl can play a deleterious role during the photoinduced process. However, the encapsulation of a fraction of DNA is not excluded. In such conditions, the DNA could be protected against the reactive oxygen species.
Clinical potential of lurasidone in the management of schizophrenia (2011)

Lurasidone is a new second-generation antipsychotic approved in October 2010 by the Food and Drug Administration for the treatment of schizophrenia. Like other second-generation antipsychotics, lurasidone is a powerful antagonist of D(2) dopamine and 5HT(2A) serotonin receptors, but differs from the other second-generation antipsychotics in its action profile for certain receptors. Lurasidone is the second-generation antipsychotic with the greatest affinity for 5HT(7) receptors and has a high affinity for 5HT(1A) serotonin receptors, compatible with favorable effects on cognitive function and an antidepressant action. By contrast, lurasidone has a low affinity for and α(1) α(2C)-adrenergic and 5HT(2C) serotonin receptors, and no affinity for histaminergic H(1) or muscarinic M(1) receptors, suggesting a better tolerability profile than the other second-generation antipsychotics. Lurasidone has demonstrated its efficacy in several short-term trials in acute schizophrenia, promptly and significantly reducing total Positive and Negative Syndrome Scale and Brief Psychiatric Rating Scale scores compared with placebo. Several long-term studies are in progress to assess its efficacy in the maintenance treatment of schizophrenic patients. The efficacy of lurasidone with regard to cognitive functions and depressive symptoms seems good, but requires further work. Lurasidone differs from the other second-generation antipsychotics by having a good tolerability profile, in particular for cardiometabolic tolerability. However, it seems to have a significant although moderate link with the occurrence of akathisia, extrapyramidal symptoms, and hyperprolactinemia at the start of treatment. This tolerance profile greatly broadens the scope of second-generation antipsychotics and so supports the view of some authors that the term "second-generation antipsychotic" is now outdated. Other therapeutic perspectives of lurasidone are assessed here, in particular bipolar depression.
Isolation and physicochemical characterization of human follicle-stimulating hormone isoforms. (1992)

Twenty hFSH isoforms were isolated from human pituitary extracts, 15 of which were highly pure. The mild purification procedure, which used a FSH RRA to monitor FSH activity, involved an initial fractionation of pituitary extracts by gel filtration and isoelectric focusing. Six pI regions (mean pI values, 3.63, 3.88, 4.07, 4.23, 4.84, and 5.13) of human (h) FSH were obtained and further fractionated on ion exchange and gel filtration HPLC. Recoveries of FSH radioreceptor activity at each stage were greater than 80%. Fifteen isoform preparations were judged as near homogeneous by HPLC-gel filtration and sodium dodecyl sulfate-polyacrylamide gel electrophoresis, exhibiting elution and migration behaviors consistent with the known mol wt of intact hFSH and its subunits. The remaining 5 isoform preparations contained a higher mol wt component that is probably hFSH related, as this component was detected after iodination, immunoprecipitation with hFSH antiserum, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Similar amino acid compositions were obtained for the 20 hFSH isoforms, except for evidence of some oxidative degradation of serine, threonine, and tyrosine and decreased levels of glutamic acid, possibly due to carboxy-terminal heterogeneity of the beta-subunit. An average amino acid composition value for all isoforms was comparable to that of 2 other highly purified hFSH preparations. Using the First International Standard for pituitary hFSH (83/575) as standard, radioreceptor activities were obtained ranging from 7,800-56,300 IU/mg protein. It is concluded that a mild purification procedure for the isolation of hFSH isoforms has been developed which gives high recoveries and has enabled the isolation of 15 isoforms in high purity suitable for further physicochemical and biological characterization.