gebhart/patrepeval huggingface dataset:
Virtual execution environment for windows applications (2011)

Application virtualization has been a trend for the architecture of Software as a Service (SaaS), which isolates applications from OS and from other applications. This paper provides a solution of virtual execution environment for windows applications, which intercepts a select subset of system calls at the user-level, incorporates the resources requested by the applications which are stored in different places through copy-on-write scheme and renaming mechanisms and implements three modules, including virtual registry, file visit virtualization and system objects virtualization in order to isolate applications from OS and from other application partially. Using the environment, the applications could be run in the host system without installation and without any changes. Experimental results demonstrate that the overhead of our solution is limited and acceptable.
Test case permutation to improve execution time (2016)

With the growing complexity of software, the number of test cases needed for effective validation is extremely large. Executing these large test suites is expensive, both in terms of time and energy. Cache misses are known to be one of the main factors contributing to execution time of a software. Cache misses are reduced by increasing the locality of memory references. For a single program run, compiler optimisations help improve data locality and code layout optimisations help improve spatial locality of instructions. Nevertheless, cache locality optimisations have not been proposed and explored across several program runs, which is the case when we run several test cases.
Robust recognition of handwritten numerals based on dual cooperative network (2003)

An approach to robust recognition of handwritten numerals using two operating parallel networks is presented. The first network uses inputs in Cartesian coordinates, and the second network uses the same inputs transformed into polar coordinates. How the proposed approach realizes the robustness to local and global variations of input numerals by handling inputs both in Cartesian coordinates and in its transformed Polar coordinates is described. The required network structures and its learning scheme are discussed. Experimental results show that by tracking only a small number of distinctive features for each teaching numeral in each coordinate, the proposed system can provide robust recognition of handwritten numerals.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Equivalence of double and single wave vector diffusion contrast at low diffusion weighting (2011)

Multiple pulsed field gradient diffusion sequences have received renewed interest in recent years as a potentially new type of MRI contrast. This attention is largely a result of the ability to measure pore sizes using low-amplitude diffusion gradients, and to distinguish between macroscopically isotropic systems of anisotropic pores and systems of isotropic pores. In this article, it is shown that, under many circumstances, the same type of information can be obtained by combining two or more standard single pulse diffusion-weighted experiments acquired at different diffusion times. Similarly, information from multiple pulsed field gradient diffusion can be reconstructed from several single pulsed diffusion experiments. This possibility is rooted in the information contained in the time dependence of the diffusion tensor, which provides a complete description of the diffusion-weighted MR signal at low gradient amplitudes. The new information arising at the fourth order in the cumulant expansion is discussed. The coupling of the wave vectors at long mixing times is found to be controlled by the variance of the single pore mean displacement tensor. In particular, a discussion is given concerning the way in which the sensitivity of the fourth-order term to the pore shape anisotropy is modulated by pore orientation anisotropy and vanishes in coherently oriented homogeneous ensembles. For macroscopically isotropic systems, a new index of pore shape anisotropy is proposed.
Cellular sensitivity to glucocorticoids in patients with POAG. Steroid receptors and responses in cultured skin fibroblasts. (1985)

The question of a generalized hypersensitivity to corticosteroids in primary open-angle glaucoma (POAG) was investigated using cultured skin fibroblasts from patients with POAG and age-matched controls. Nuclear binding of (3H)-dexamethasone was performed to evaluate possible changes in the glucocorticoid receptors. Cortisol effects on (3H)-thymidine uptake into the cells were investigated as a measure of the cellular sensitivity to corticosteroids. When POAG and control groups were compared, no significant differences (P less than 0.05) were found for either the number or affinity of glucocorticoid receptors (POAG: Kd = 6.1 +/- 1.0 nM, Rt = 94 +/- 13 sites/cell X 10(3); control: Kd = 5.5 +/- 1.6 nM, Rt = 124 +/- 20 X 10(3) sites/cell) or for cortisol effects on thymidine uptake (POAG: C50 = 83 +/- 38 nM; control: C50 = 80 +/- 34 nM). Use of epidermal growth factor (EGF) resulted in an increased steroid sensitivity in some cell lines, but again no differences between POAG and control groups were detected. These results suggest that a generalized cellular hypersensitivity to glucocorticoids is not intrinsic to POAG. It is possible that environmental alterations and/or endogenous factors may influence the steroid responses observed in these patients.
The association between C‐reactive protein on admission and mortality in patients with acute myocardial infarction (2000)

Patients with elevated concentrations of serum C-reactive protein admitted to the hospital because of acute myocardial infarction are at an increased risk of dying. This association is however, largely explained by other baseline variables, in particular by an estimate of the duration of myocardial ischaemia. If C-reactive protein measured by means of an ultra-sensitive assay is more suitable for risk stratification of unselected patients with acute myocardial infarction, needs further study.
Deep sequencing of HPV16 genomes: A new high-throughput tool for exploring the carcinogenicity and natural history of HPV16 infection (2015)

For unknown reasons, there is huge variability in risk conferred by different HPV types and, remarkably, strong differences even between closely related variant lineages within each type. HPV16 is a uniquely powerful carcinogenic type, causing approximately half of cervical cancer and most other HPV-related cancers. To permit the large-scale study of HPV genome variability and precancer/cancer, starting with HPV16 and cervical cancer, we developed a high-throughput next-generation sequencing (NGS) whole-genome method. We designed a custom HPV16 AmpliSeq™ panel that generated 47 overlapping amplicons covering 99% of the genome sequenced on the Ion Torrent Proton platform. After validating with Sanger, the current "gold standard" of sequencing, in 89 specimens with concordance of 99.9%, we used our NGS method and custom annotation pipeline to sequence 796 HPV16-positive exfoliated cervical cell specimens. The median completion rate per sample was 98.0%. Our method enabled us to discover novel SNPs, large contiguous deletions suggestive of viral integration (OR of 27.3, 95% CI 3.3-222, <i>P</i>=0.002), and the sensitive detection of variant lineage coinfections. This method represents an innovative high-throughput, ultra-deep coverage technique for HPV genomic sequencing, which, in turn, enables the investigation of the role of genetic variation in HPV epidemiology and carcinogenesis.
Error control codes for parallel asymmetric channels (2006)

We introduce and study error correcting codes for parallel synchronous communication via Z-channels. Constructions for error detecting/correcting codes are presented. More generally, we consider array codes for Z-channels
A migratory population of skin-derived dendritic cells expresses CXCR5, responds to B lymphocyte chemoattractantin vitro, and co-localizes to B cell zones in lymph nodesin vivo (2000)

Chemokine receptors on dendritic cells (DC) and chemokines within lymph nodes (LN) contribute to trafficking of DC to appropriate sites within the LN. Here we show that DC that have migrated out of skin ex vivo (migratory DC, migDC) express 50-fold more CXCR5 mRNA than fresh Langerhans cells and migrate in response to B lymphocyte chemoattractant (BLC) in vitro. When injected into the footpad of mice, migDC emigrate to regional LN where up to 40% are found in B cell zones. By contrast, murine bone marrow-derived DC display 14-fold less CXCR5, do not migrate to BLC in vitro, and migrate strictly to T cell zones in LN. We propose that activated skin DC utilize CXCR5 and BLC as a possible mechanism to home to B cell zones of LN, where they may have direct effects on B cells.
Full Phononic Bandgap in 2D-Optomechanical Crystals (2011)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text T. P. Mayer Alegre, A. H. Safavi-Naeini, M. Winger, and O. Painter, "Full Phononic Bandgap in 2D-Optomechanical Crystals," in CLEO:2011 - Laser Applications to Photonic Applications, OSA Technical Digest (CD) (Optica Publishing Group, 2011), paper CFA1. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
New force sensor based on a double ended tuning fork (2002)

This paper introduces an original force sensor, constituted by two elements, designed to be directly sensitive to compressive forces. This is achieved by using a specific element which transforms the compressive force applied on it into a tensile force on the beams of a DETF. First, after a description of the sensor, the working principle of the proposed device is related. The choice of the used vibrational mode is justified in the description of the dynamic behavior of the DETF. Then, the way of applying the force is treated and the measurement principle is given. Second, in order to design the structure, a Finite Element Analysis has been performed and the predicted results are reported. Next, the designed prototype and the associated experimental set-up is described. Finally, the results of the experiments performed on the prototype are studied and a comparison with the Finite Element simulations is proposed.
Zeolite-like Behavior of a Coordination Network (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTZeolite-like Behavior of a Coordination NetworkD. Venkataraman, Geoffrey B. Gardner, Stephen Lee, and Jeffrey S. MooreCite this: J. Am. Chem. Soc. 1995, 117, 46, 11600–11601Publication Date (Print):November 1, 1995Publication History Published online1 May 2002Published inissue 1 November 1995https://doi.org/10.1021/ja00151a034RIGHTS & PERMISSIONSArticle Views1030Altmetric-Citations290LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (965 KB) Get e-AlertscloseSupporting Info (3)»Supporting Information Supporting Information Get e-Alerts
Expression Profiling of Archival Renal Tumors by Quantitative PCR to Validate Prognostic Markers (2007)

Formalin-fixed paraffin-embedded (FFPE) tissues are routinely stored by most pathology departments and are a widely available resource for discovery of clinically useful biomarkers. We describe our method for optimizing quantitative reverse transcription PCR (RT-PCR) for expression analysis using frozen and archival tissue. Commonly used reference genes were evaluated for stability of expression in normal kidney and clear cell renal cell carcinoma (RCC). Optimal reference genes for calculating normalization factors for RT-PCR were ACTB, RPL13A, GUS, RPLP0, HPRT1, and SDHA when using FFPE RCC. The optimal reference genes when using frozen RCC were ACTB, RPL13A, and GUS, confirming that use of multiple reference genes improves accuracy when intact RNA from frozen renal tumors are used. Expression of 16 markers previously reported to have prognostic significance in RCC was determined in 23 matching frozen and FFPE renal tumors, representing a range of tumor grades and stages; correlation coefficient for expression measured in frozen and FFPE tumors was 0.921 (P<0.001). All markers predicted survival when frozen tumors were used and 14 of the 16 markers predicted survival when FFPE tumors were used as the source of RNA. An optimized RT-PCR assay can accurately measure expression of most prognostic tumor markers.
Coupled Nonuniform Transmission Line and Its Applications (1967)

Theory and applications of coupled nonuniform transmission lines are described. Matrix representations of a general coupled nonuniform transmission line are presented, by means of which the behavior of any coupled nonuniform transmission line maybe completely described. Among a wide variety of applications of coupled nonuniform transmission lines, two typical networks, one the coupled nonuniform transmission-line folded all-pass network and the other the coupled nonuniform transmission-line directional coupler, are treated in detail. Equivalent circuit representatious of these two networks are presented, which enable the designer to synthesize them in a greatly simplified manner by making use of the theories now available for more conventional single nonuniform transmission lines. In addition, the properties of these two networks using coupled exponential line are investigated. Design procedure is also given for asymmetrical coupled exponential-line directional couplers having excellent characteristics.
<title>Use of AEDC's laser-based direct-write scene generator to drive NAWC's fiber array projector</title> (1999)

The operation of the Direct Write Scene Generator (DWSG) to drive a fiber array projection system is reported in this paper. The fiber array absorbs the input radiation from the laser-based system and produces broadband infrared output through blackbody cavities fabricated on the ends of the optical fibers. A test program was begun to quantify the performance of the fiber array with respect to input laser, power, temporal response, spatial uniformity, IR output, and fiber-to-fiber crosstalk. Static and dynamic scenes will also be projected with the device and captured with a camera system. Preliminary projection of a simple scene has been accomplished.
Artist-In-Residence Recital (2010)

Program listing performers and works performed.
CMOS technology for low voltage/low power applications (2002)

In this paper, the scaled CMOS as the ideal technology for the low power revolution, is discussed. It is shown that by the proper scaling of the CMOS devices, improved performance, power, and density can be achieved SIMULTANEOUSLY. The above scaling is made possible by; the reduction of the supply voltage, and the improved manufacturing tolerances and minimum dimensions. The reduction of the supply voltage is needed to lower the power dissipation per device and to maintain adequate reliability at improved performance. The CMOS technologies ranging from 0.25 /spl mu/m CMOS @ 2.5 V down to 0/1 /spl mu/m @ 1.XV on bulk and SOI (Silicon On Insulator) are presented. Over two orders of magnitude improvement in power x delay (mW/MIPS) is expected by the scaling of CMOS down to the 0.1 /spl mu/m (Leff) regime.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Identity of Passive Film Formed on Aluminum in Li-Ion Battery Electrolytes with LiPF[sub 6] (2006)

The passive film that forms on aluminum in 1:1 ethylene carbonate with and 1:1 ethylene carbonate with was investigated by a combination of electrochemical quartz crystal microbalance measurements (EQCM), electrochemical impedance spectroscopy (EIS), and X-ray photoelectron spectroscopy. During anodic polarization of aluminum a film of forms on top of the air-formed oxide, creating a duplex, or two-layered film. The thickness of the increases with the applied potential. Independent measurements of film thickness by EQCM and EIS indicate that at a potential of vs , the thickness of the is approximately .
Health Risks and Benefits 3 Years After Stopping Randomized Treatment With Estrogen and Progestin (2008)

clinicaltrials.gov Identifier: NCT00000611.
Syntheses of Lamellarins I and K by [3 + 2] Cycloaddition of a Nitrone to an Alkyne (2001)

Lamellarins I and K were obtained by a new approach based on the 1,3-dipolar cycloaddition of a nitrone to an alkyne. The key cycloaddition yields an isoxazoline which rearranges to afford the central pyrrole ring.
Lipid Transfer Proteins in Plants and Microorganisms (1992)

Lipid transfer proteins (LTPs) have been isolated as the proteins which transfer lipids between membranes by in vitro assays. Phosphatidylcholine-specific LTPs and phosphatidylinositol-specific LTPs are found in higher plants and fungi, respectively. LTPs that transfer many classes of lipids nonspecifically are also found in higher plants. The structure, gene expression and function of these LTPs are described.
Pain in spinal cord injury (1991)

Abstract Sustaining a spinal cord injury (SCI), even a severe one, does not necessarily entail pain, although the majority of SCI patients in the acute phase do experience pain, which usually subsides with medical management. In the chronic phase, however, about one-third of SCI patients complain of sensory disturbances, either pain or unpleasant sensations called dysaesthesiae. In chronic SCI patients it is not only the incidence of pain, but its intractability which is important. While treating these patients two problems have to be dealth with: one is the chronic pain syndrome, with all its complexities; and the other is a chronic neurogenic dysfunction. The need for treatment of chronic pain continues, and the potential for developing drug-tolerance and addiction must be addressed prior to the onset of therapy. This chapter concentrates upon neurogenic pain in SCI, particularly pain which might have been caused by injury to the spinal cord.
Treatment of Classic Pantothenate Kinase–Associated Neurodegeneration with Deferiprone and Intrathecal Baclofen (2013)

Neurodegeneration with brain iron accumulation (NBIA) describes a heterogeneous family of diseases characterized by high brain iron, particularly in the basal ganglia. The most common manifestation of childhood NBIA is classic pantothenate kinase-associated neurodegeneration (PKAN), a severe, progressive type of autosomal recessive neuroaxonal dystrophy characterized by early onset of symptoms (as opposed to atypical PKAN, with an average age of onset of 14 yrs). There is currently no established therapy for the disease. Intrathecal baclofen has been reported to improve ease of care and dystonia in patients with PKAN. Deferiprone, an iron chelator, has been shown to be safe and tolerable in patients with PKAN as well as effective in reducing brain iron accumulation, as measured by magnetic resonance imaging. This case report highlights the potency of combining intrathecal baclofen and oral deferiprone in a patient with classic PKAN. Although treatment with deferiprone alone was not attempted, this combination therapy seems to be more efficacious than treatment with only intrathecal baclofen.
Cytotoxic Constituents of<i>Bursera permollis</i> (1995)

Four cytotoxic lignans were isolated from the stem bark of Bursera permollis (Burseraceae), namely, deoxypodophyllotoxin (1), beta-peltatin methyl ether (2), picro-beta-peltatin methyl ether (3), and dehydro-beta-peltatin methyl ether (4). Also isolated was the inactive lignan, nemerosin (5). Compounds 1 and 2 were potently cytotoxic when evaluated against a panel of human cancer cell lines.
Consistent linear speedup in parallel alpha-beta search (2003)

Alpha-beta search is an important heuristic technique used in pruning a game tree. Recently, parallelism has been introduced to further improve the efficiency of such heuristic searches. The paper presents a new parallel alpha-beta search algorithm that applies a prioritizing scheme. To verify its performance, the algorithm was implemented on sequent symmetry shared memory multiprocessor system. Experimental results show that for the best ordering uniform trees, one is able to obtain a consistent speedup of a linear order to the number of processors used. An overall speedup with random node ordering is illustrated. The paper concludes with some characteristics of the alpha-beta search that make the application of priorities suitable for its corresponding parallel algorithm.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
EXPRESSION OF PARATHYROID HORMONE‐RELATED PROTEIN mRNA IN TUMORS OBTAINED FROM PATIENTS WITH HUMORAL HYPERCALCEMIA OF MALIGNANCY (1988)

Human parathyroid hormone-related protein (PTHrP) mRNA was detected in all fresh cancer tissues consecutively obtained from 6 patients with humoral hypercalcemia of malignancy (HHM). The primary sites of the cancers in these cases were distributed among different organs including the lung, esophagus, kidney and ovary. PTHrP mRNA was undetectable in all 10 fresh cancer tissues obtained from normocalcemic patients. These results suggest PTHrP as a major cause of HHM.
Analysis of aircraft maintenance processes and cost (2020)

The life cycle of an aircraft consists of design, production, operation and decommissioning phases. For an airline the main focus is on the maintenance process during the operation phase. This paper presents a case study of an airline facing a challenge of increasing maintenance cost. The objective is to understand factors that drive increase in cost. Maintenance cost, flight hours, flight cycles, dispatch reliability and pilot reports were analyzed to find out the maintenance cost drivers. The study identified that the aircraft which dominated the maintenance costs had the highest flight hours, and the lowest dispatch reliability in the fleet.
[Construction of a pufferfish bacterial artificial chromosome library]. (1998)

The library accords with the demands of a BAC library.