gebhart/patrepeval huggingface dataset:
Vascular C-Reactive Protein in the Pathogenesis of Coronary Artery Disease:Role of Vascular Inflammation and Oxidative Stress (2006)

Atherosclerosis is considered to be a chronic inflammatory disease. Vascular inflammation occurs in response to injury induced by various stimuli, such as oxidative stress, shear stress, infection, and so on. This concept is supported by the recent clinical findings that C-reactive protein (CRP) is an independent risk factor for coronary heart disease. CRP, which was originally identified as a protein that could precipitate the C-polysaccharide of pneumococcal cell walls, has been widely used as a clinical marker of the state of inflammation, since its production by hepatocytes increases during the acute phase of the inflammatory response. Recent investigations have provided two new concepts for the research field of CRP, namely, its extra-hepatic production and its potent biological activities such as the induction of adhesion molecules and chemokines. Recently, we demonstrated that smooth muscle cells and macrophages in coronary arteries expressed CRP protein and mRNA, as evaluated using coronary specimens of coronary artery disease (CAD) patients obtained by atherectomy. The expression of vascular CRP was closely associated with NAD(P)H oxidase, an important enzymatic origin of reactive oxygen species (ROS) in vessel walls. Furthermore, CRP directly up-regulated NAD(P)H oxidase p22(phox) and enhanced ROS generation in cultured coronary artery smooth muscle cells. Thus, vascular CRP is likely to be a direct participant in vascular inflammation and lesion formation via its potent biological effects. Since lysophosphatidylcholine, a major atherogenic lipid of oxidized LDL, was reported to activate vascular NAD(P)H oxidase, we speculate that there is a vicious circle consisting of vascular NAD(P)H oxidase, ROS and oxidized LDL. Since phagocytic NAD(P)H oxidase is at the first line of the host defense system, it is important to selectively suppress vascular NAD(P)H oxidase in the localized inflammatory lesions in therapeutic strategies for CAD. In this review, we will discuss the roles of vascular CRP and NAD(P)H oxidase in the pathogenesis of CAD from the viewpoint of oxidative stress.
Theoretical Model for Nanoporous Carbon Supercapacitors (2007)

Importance of pore curvature: A theoretical model is proposed for nanoporous carbon supercapacitors to replace the commonly used one for an electric double-layer capacitor (EDLC) on the basis of an electric double-cylinder capacitor (EDCC) for mesopores, which becomes an electric wire-in-cylinder capacitor (EWCC) for micropores (see picture; left to right: decreasing pore size). This model explains the experimental data in various pore ranges, showing the significance of pore curvature. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z703864_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Dynamic Adaption of DCF and PCF mode of IEEE 802.11 WLAN (2003)

IEEE 802.11 specifies the most famous family of WLANs. It features two basic mode of operation: Distributed Coordinating Function (DCF) and Point Coordinating Function (PCF). Both PCF and DCF mode of IEEE 802.11 do not perform equally well under all tra#c scenarios. Their behavior varies depending upon current network size and tra#c load. It is useful to use the DCF mode for low tra#c and small network size, and the PCF mode for high tra#c loads and to reduce contention in large size network. In this thesis, we have designed three protocols to dynamically adapt IEEE 802.11 MAC under varying load. One of them is designed to dynamically switch between either modes. Our Dynamic Switching Protocol (DSP) observes network tra#c to decide switching point and switches dynamically to suit current tra#c load and network size.
A simplified algorithm for correcting both errors and erasures of R-S codes (1978)

Using the finite field transform and continued fractions, a simplified algorithm for decoding Reed-Solomon (R-S) codes is developed to correct erasures caused by other codes as well as errors over the finite field GF (q(m), where q is a prime and m is an integer. Such an R-S decoder can be faster and simpler than a decoder that uses more conventional methods.
Properties of Maxillofacial Silicone Elastomers Reinforced with Silica Powder (1998)

Compounds of a silicone elastomer suitable for preparing maxillofacial prostheses, reinforced with various amounts of silica powder, have been studied for their mechanical response and wetting properties in terms of contact angle. Tensile strength and elongation at break showed an increase with increasing silica volume fraction up to 35%, whereas the Young modulus displayed small dependence on the silica content and the resistance to tear increased continuously with filler volume fraction (Vf). The wetting properties assessed via the contact angle, seemed to degrade with increasing silica Vf, but a dependence on the elastomer network density has also been recorded.
Malnutrition in Chronic Kidney Disease (2018)

Patients with chronic kidney disease are at substantial risk for malnutrition, characterized by protein energy wasting and micronutrient deficiency. Studies show a high prevalence rate of malnutrition in both children and adults with chronic kidney disease. Apart from abnormalities in growth hormone-insulin like growth factor axis, malnutrition also plays a role in the development of stunted growth, commonly observed in children with chronic kidney disease. The pathogenic mechanisms of malnutrition in chronic kidney disease are complex and involve an interplay of multiple pathophysiologic alterations including decreased appetite and nutrient intake, hormonal derangements, metabolic imbalances, inflammation, increased catabolism, and dialysis related abnormalities. Malnutrition increases the risk of morbidity, mortality and overall disease burden in these patients. The simple provision of adequate calorie and protein intake does not effectively treat malnutrition in patients with chronic kidney disease owing to the intricate and multifaceted derangements affecting nutritional status in these patients. A clear understanding of the pathophysiologic mechanisms involved in the development of malnutrition in chronic kidney disease is necessary for developing strategies and interventions that are effective, and capable of restoring normal development and mitigating negative clinical outcomes. In this article, a review of the pathophysiologic mechanisms of malnutrition in chronic kidney disease is presented.
Pulse voltammetry in single cells using platinum microelectrodes (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPulse voltammetry in single cells using platinum microelectrodesTa Kung. Chen, Yau Yi. Lau, Danny K. Y. Wong, and Andrew G. EwingCite this: Anal. Chem. 1992, 64, 11, 1264–1268Publication Date (Print):June 1, 1992Publication History Published online1 May 2002Published inissue 1 June 1992https://pubs.acs.org/doi/10.1021/ac00035a013https://doi.org/10.1021/ac00035a013research-articleACS PublicationsRequest reuse permissionsArticle Views275Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Three Escherichia coli heat shock proteins are required for P1 plasmid DNA replication: formation of an active complex between E. coli DnaJ protein and the P1 initiator protein. (1990)

DNA containing the plasmid origin of bacteriophage P1 is replicated in vitro by a protein fraction prepared from uninfected Escherichia coli supplemented with purified P1 RepA protein. It has previously been shown that the reaction required the E. coli DnaA initiator protein, the DnaB helicase, DnaC protein, RNA polymerase, and DNA gyrase. I show here that three E. coli heat shock proteins, DnaJ, DnaK, and GrpE, are directly involved in P1 plasmid replication. Purified DnaJ, DnaK, and GrpE proteins were required to stimulate P1 plasmid ori DNA-dependent replication in in vitro complementation assays in which the host protein fractions were prepared from cells mutated in the corresponding gene. I have also found that the DnaJ and RepA proteins form a complex. This complex exists in crude cell extracts and can be isolated as a molecular species of about 160,000 Da containing one dimer of DnaJ protein and one dimer of RepA. The complex can also be reconstituted by mixing purified DnaJ and RepA proteins. These results imply that the DnaJ-RepA complex, DnaK, and GrpE are directly involved in P1 plasmid replication.
Current Sensor Based on Rogowski Coil. (2017)

We have built several Rogowski coil current sensors for measuring currents in non sinusoidal systems. In this paper we present the sensor and his behavior. We have built a generator of pulses in order to test it and we compare the results between two types of coils (flexible and Printed Circuit board PCB designed) and the linearity for measuring currents.
Cooperative integration of multiple stereo matching algorithms (1992)

Abstract This paper describes a method in which three kinds of stereo matching methods based on different image features are integrated by a cooperative processing to realize a matching search system applicable to a wide range of objects. In other words, the point‐based matching using correlation, the interval‐based matching using edges and the segment‐based matching using connected edges are combined. The module for dedicated execution of each algorithm is provided, and the modules execute the matching search in parallel. Whenever necessary, the partial result of the processing is exchanged to realize a complementary cooperation. Each module continues the processing for the part which can be processed without being assisted by other modules. Then, considering each local area of the image, the best‐suited algorithm is selected and applied automatically according to the situation. Each module evaluates the extent of confidence of its own processing, and the reliability score is attached when the result of processing is exchanged. The module receiving the data appropriately considers the received data into its own processing, according to the confidence. The disparity image generation module integrates the results of three matchings according to the extent of confidence. The method is applied to several stereo images, and the usefulness of the proposed method is demonstrated.
2D and 3D prestack seismic data regularization using an accelerated sparse time-invariant Radon transform (2014)

ABSTRACT The time-invariant Radon transform (RT) is commonly used to regularize and interpolate sparsely sampled or irregularly acquired prestack seismic data. The sparseness of the Radon model significantly influences the results of regularization. We have developed an effective and efficient method for the regularization and interpolation of 2D as well as 3D prestack seismic data. We used an accelerated sparse time-invariant RT in the mixed frequency-time domain to improve the performance of RT-based seismic data regularization. This 2D sparse RT incorporated the iterative 2D model shrinkage algorithm instead of the traditional iteratively reweighted least-squares (IRLS) algorithm in the time domain, and we computed the forward and inverse RTs in the frequency domain to solve the sparse inverse problem, which dramatically reduced the computational cost while obtaining a high-resolution result. The 2D synthetic and real data examples revealed that our 2D approach can better interpolate beyond aliasing a 2D prestack seismic record that contains a large gap, compared with the least-squares-based RT and the frequency-domain sparse RT methods. To extend the 2D technique to 3D more efficiently, we first formulate the 3D RT as a problem of solving a special matrix equation. Next, we use the iterative 3D model shrinkage algorithm to obtain a high-resolution 3D Radon model. The proposed 3D sparse RT method can be applied in the regularization of 3D prestack gathers, such as in the cable interpolation in a 3D marine survey. We achieved robustness and effectiveness with our 3D approach with successful applications to 3D synthetic and real data.
A simple risk score effectively predicted type 2 diabetes in Iranian adult population: population-based cohort study (2010)

We presented a simple model based on SBP, family history of diabetes, WHtR, TG/HDL-C and FPG; concluding that this approach is superior to relying exclusively on the 2h-PCPG for identifying individuals at high risk for developing diabetes in a Middle Eastern adult population.
Accurate Line Shapes from Sub-1 cm<sup>–1</sup> Resolution Sum Frequency Generation Vibrational Spectroscopy of α-Pinene at Room Temperature (2015)

Despite the importance of terpenes in biology, the environment, and catalysis, their vibrational spectra remain unassigned. Here, we present subwavenumber high-resolution broad-band sum frequency generation (HR-BB-SFG) spectra of the common terpene (+)-α-pinene that reveal 10 peaks in the C-H stretching region at room temperature. The high spectral resolution resulted in spectra with more and better resolved spectral features than those of the Fourier transform infrared, femtosecond stimulated Raman spectra in the bulk condensed phase and those of the conventional BB-SFG and scanning SFG spectroscopy of the same molecule on a surface. Experiment and simulation show the spectral line shapes with HR-BB-SFG to be accurate. Homogeneous vibrational decoherence lifetimes of up to 1.7 ps are assigned to specific oscillators and compare favorably to lifetimes computed from density functional tight binding molecular dynamics calculations. Phase-resolved spectra provided their orientational information. We propose the new spectroscopy as an attractive alternative to time domain vibrational spectroscopy or heterodyne detection schemes for studying vibrational energy relaxation and vibrational coherences in molecules at molecular surfaces or interfaces.
A Situation Report - Iowa State's "Closed" Dairy Herd (1962)

A Holstein herd at Iowa State has been closed to outside blood for about 30 years. Here are some developments to date regarding the effect of selection and the results of mild inbreeding that occured in the herd.
Recognition accuracy and usability of pen-based interfaces (1996)

Questions whether devices capable of handwriting recognition are likely to appeal to those who have relatively little experience of computing, and have poor keyboard skills. The answer seems to be that pen computing can be an attractive prospect for this group of potential users, although it is the inability to type rather than lack of computer experience which matters. User attitudes appear to be driven by an assessment of the relative costs of using the device. This takes account not only of the effort required by non-typists to use the keyboard, but also of the perceived difficulty of writing legibly. As the experience of using the pen for text input alerted subjects to the consequences of recognition failures, this became a significant factor in the assessment of costs and benefits. At the same time, the focus of the evaluation also shifted from the input medium to the task. The inconvenience of writing in a particular style, and of correcting recognition errors, could be offset against the perceived benefits of using the pen within a particular application. The effect of this broader assessment of both costs and benefits was to reduce the significance of user characteristics. The highly positive evaluations of our application demonstrates that it is possible to design successful software for pen applications, despite the limited performance of current recognisers. Although new groups of users may initially be attracted by the idea of pen computing these applications are likely to be judged on their merits by all users, regardless of their existing skills. (6 pages)
Essential Role of Caveolin-3 in Adiponectin Signalsome Formation and Adiponectin Cardioprotection (2012)

Taken together, these results demonstrated for the first time that Cav-3 plays an essential role in APN transmembrane signaling and APN anti-ischemic/cardioprotective actions.
Boron bromide as a source precursor for low energy applications (2002)

The use of boron tri-bromide as a source precursor for low energy boron implantation is studied in this work. Details of gas delivery system, beam purity and running performance have been investigated for a 75keV molecular implant to give an equivalent boron energy of 5keV. The behavior of the Br during thermal processing is compared to that of F derived from a BF <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> implant and is seen to be less mobile during post implant rapid thermal annealing with implications to gate oxide performance.
Smart laser-scanner for 3D human-machine interface (2005)

The problem of tracking hands and fingers on natural scenes has received much attention using passive acquisition vision systems and computationally intense image processing. We are currently studying a simple active tracking system using a laser diode, steering mirrors, and a single non-imaging detector, which is capable of acquiring three dimensional coordinates in real time without the need of any image processing at all. Essentially, it is a smart rangefinder scanner that instead of continuously scanning over the full field of view restricts its scanning area, on the basis of a real-time analysis of the backscattered signal, to a very narrow window precisely the size of the target. The complexity of the whole setup is equivalent to that of a portable laser-based barcode reader, making the system compatible with wearable computers.
Expiratory flushing of airways: a method to reduce deadspace ventilation (1990)

A jet of fresh gas entering the trachea during the last part of expiration, expiratory flushing of airways (EFA), may during mechanical ventilation bring the fresh gas interface into the trachea to reduce deadspace. EFA, delivered in a variety of modes, was tested in healthy dogs. EFA allowed tidal volume, peak and mean airway pressure to be reduced by about 25%. EFA was administered in the form of pulses with frequencies 2-8 Hz, and as a continuous flow. The mode was of little importance. EFA was found to be efficient and should be clinically tested.
MEBF: a fast and efficient Boolean matrix factorization method. (2019)

Boolean matrix has been used to represent digital information in many fields, including bank transaction, crime records, natural language processing, protein-protein interaction, etc. Boolean matrix factorization (BMF) aims to find an approximation of a binary matrix as the Boolean product of two low rank Boolean matrices, which could generate vast amount of information for the patterns of relationships between the features and samples. Inspired by binary matrix permutation theories and geometric segmentation, we developed a fast and efficient BMF approach called MEBF (Median Expansion for Boolean Factorization). Overall, MEBF adopted a heuristic approach to locate binary patterns presented as submatrices that are dense in 1's. At each iteration, MEBF permutates the rows and columns such that the permutated matrix is approximately Upper Triangular-Like (UTL) with so-called Simultaneous Consecutive-ones Property (SC1P). The largest submatrix dense in 1 would lies on the upper triangular area of the permutated matrix, and its location was determined based on a geometric segmentation of a triangular. We compared MEBF with other state of the art approaches on data scenarios with different sparsity and noise levels. MEBF demonstrated superior performances in lower reconstruction error, and higher computational efficiency, as well as more accurate sparse patterns than popular methods such as ASSO, PANDA and MP. We demonstrated the application of MEBF on both binary and non-binary data sets, and revealed its further potential in knowledge retrieving and data denoising.
Monochord — pythagoreisches Stimmungsprinzip (1982)

Den Naturwissenschaftlern der Neuzeit erscheint es befremdlich, daß die Philosophen der Antike zu naturwissenschaftlichen Problemen Behauptungen aufstellten, ohne deren Wahrheitsgehalt jemals mit leicht ausführbaren Experimenten nachzuprüfen. Zum Beispiel läßt sich die Behauptung des Aristoteles (384–322 v. u. Z.), daß schwere Körper schneller fallen als leichte, mit einem einfachen Gedankenexperiment widerlegen: Es ist ohne Einfluß auf die Fallzeit, ob man zwei Kilogrammstücke getrennt in einen tiefen Brunnen wirft oder ob man sie vor dem Versuch fest miteinander verbindet.
Piezoresistor-Embedded Multifunctional Magnetic Microactuators for Implantable Self-Clearing Catheter (2018)

Indwelling catheters are used widely in medicine to treat various chronic medical conditions. However, chronic implantation of catheters often leads to a premature failure due to biofilm accumulation. Previously we reported on the development of a self-clearing catheter by integrating polymer-based microscale magnetic actuators. The microactuator provides an active anti-biofouling mechanism to disrupt and remove adsorbed biofilm on demand using an externally applied stimulus. During an <i>in vivo</i> evaluation of self-clearing catheter, we realized that it is important to periodically monitor the performance of implanted microactuators. Here we integrate gold-based piezoresistive strain-gauge on our magnetic microactuators to directly monitor the device deflection with good sensitivity (0.035%/Deg) and linear range (±30°). With the integrated strain-gauge, we demonstrate the multi-functional capabilities of our magnetic microactuators that enable device alignment, flow-rate measurement, and obstruction detection and removal towards the development of chronically implantable self-clearing smart catheter.
MR. STRAWSON ON REFERRING (1957)

Journal Article MR. STRAWSON ON REFERRING Get access BERTRAND RUSSELL BERTRAND RUSSELL Search for other works by this author on: Oxford Academic Google Scholar Mind, Volume LXVI, Issue 263, July 1957, Pages 385–389, https://doi.org/10.1093/mind/LXVI.263.385 Published: 01 July 1957