gebhart/patrepeval huggingface dataset:
Traumatic Brain Injury (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The ZLAB Color Appearance Model for Practical Image Reproduction Applications (1998)

At its May, 1997 meeting in Kyoto, CIE TC1-34 considered 4 proposed color appearance models for adoption as the CIECAM97s model. The ZLAB model was one of those considered. Although it was rejected by TC1-34 because of its simplicity, there are many situations (such as typical crossmedia image reproduction) for which a more complex model might not be necessary, or even useful. Thus, the ZLAB model is being published as a simpler alternative to CIECAM97s that retains many of its positive features.
MultiScheme: A Parallel Processing System Based on MIT (Massachusetts Institute of Technology) Scheme. (1987)

Abstract : MultiScheme is a fully operational parallel-programming system based upon the Scheme dialect of Lisp. Like its Lisp ancestors, MultiScheme provides a conducive environment for prototyping and testing new linguistic structures and programming methodologies. MultiScheme supports a diverse community of users who have a wide range of interests in parallel programming. MultiScheme's flexible support for system-based experiments in parallel processing has enabled it to serve as a development vehicle for university and industrial research. At the same time, MultiScheme is sufficiently robust, and supports a sufficiently wide range of parallel-processing applications, that it has become the base for a commercial product, the Butterfly Lisp System produced by BBN Advanced Computers, Inc.
Synthesis and Characterization of LaNixCo1-xO3 Perovskites via Complex Precursor Methods (2010)

This work presents a study on the synthesis of LaNixCo1-xO3 perovskites via complex precursor methods. Perovskite oxides with the composition LaNixCo1-xO3 were synthesized by chelating precursor and polymeric precursor methods using nickel and/or cobalt nitrates, lanthanum nitrate, ethylene glycol, citric acid, and EDTA as starting source. The obtained perovskite were characterized by thermogravimetric analysis, infrared spectroscopy, X-ray diffraction and the morphology of the samples were investigated by N2 adsorption experiments and average medium particle size. TG curves and FTIR spectra were particularly useful in establishing of the optimal calcination temperature of the precursor powders. X-ray diffraction patterns revealed the formation of the perovskite structure in all samples prepared by both synthesis method and after calcinations at 700℃. The results showed that the preparation method resulted in oxides with the intended structure. The specific surface area values were influenced by preparation method.
Acquisition sequences in PPM communications (Corresp.) (1987)

In pulse position modulation (PPM) communications an acquisition sequence is needed to establish frame synchronization for subsequent data transmission. This sequence must have PPM structure (one pulse per frame) and desirable autocorrelation properties for its detection. The problem of finding aperiodic PPM acquisition sequences having the minimum possible autocorrelation for all off-shifted positions is investigated. Sequences with the maximum possible number of frames have been found up to frame size <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">15</tex> . Examples are given for every frame length up to <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">88</tex> , and powers of two up to <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1024</tex> . An interesting relation between the PPM sequence problem, Costas and sonar arrays, and Golomb's ruler is explored.
Salmonella typhimurium infection in calves: cell-mediated and humoral immune reactions before and after challenge with live virulent bacteria in calves given live or inactivated vaccines (1983)

Groups of six calves, 4 to 5 weeks old, were vaccinated either orally with a live auxotrophic Salmonella typhimurium (O-antigen 1,4,12) SL1479 vaccine (10(8) bacteria on day zero, 10(10) bacteria on days 7 and 14) or subcutaneously with a heat-inactivated (56 degrees C, 30 min) S. typhimurium SVA1232 vaccine (10(10) bacteria suspended in 30% [vol/vol] aluminum hydroxide on days zero, 7, and 14). The calves were then orally challenged with either 10(6) (approximately 100 X the 25% lethal dose) or 10(9) (approximately 100,000 X the 25% lethal dose) live bacteria of the calf-virulent S. typhimurium SVA44 strain. The immune reactivity of these calves and of nonvaccinated control calves was followed before and after the challenge infection up to 42 days by (i) intradermal injection of S. typhimurium crude extract, outer membrane protein preparation (porins), and lipopolysaccharide (LPS), (ii) in vitro stimulation of peripheral blood lymphocytes estimated by using uptake of [3H]thymidine, with S. typhimurium crude extract, porins, LPS, and polysaccharide (O-antigenic polysaccharide chain free of lipid A), and Salmonella sp. serotype thompson (O-antigen 6,7) strain IS40 LPS and polysaccharide, and (iii) estimation of the class-specific immunoglobulin G (IgG) and IgM antibody responses against S. typhimurium LPS and porins, and Salmonella sp. serotype thompson LPS. The immune studies showed that in calves given the live vaccine orally, the skin test reactivity and lymphocyte stimulation indices were significantly higher (P values ranging from less than 0.025 to less than 0.0005) against homologous, but not heterologous, antigens than those seen in calves given the heat-inactivated vaccine subcutaneously. In contrast, the IgG and IgM antibody titers against homologous LPS and porins were significantly higher (P less than 0.0005) in sera collected on day 21 from calves given the heat-inactivated vaccine than in calves given the live vaccine. After the oral challenge, calves given the live vaccine showed reduced cell-mediated immune reactions, in agreement with the observation that the host defense could eradicate the challenge organism, whereas calves given the heat-inactivated vaccine showed significantly increased cell-mediated immune reactions (P values ranging from less than 0.025 to less than 0.005), in agreement with the observation that in these calves, the challenge strain caused enteritis as well as systemic invasion. The increased cell-mediated immune reactivity in calves given the live vaccine correlated well with the excellent protection against challenge infection seen in these animals.
Respiratory Isozyme, Two Types of Rusticyanin of<i>Acidithiobacillus ferrooxidans</i> (2003)

Among the members of the copper protein superfamily, the type I enzyme rusticyanin, which is found as an electron carrier in the oxidative respiratory chain of Acidithiobacillus ferrooxidans, is the only one to have both a high redox potential and acid stability. Here we report that two forms of the rusticyanin gene (rus) are present in the genomes of some strains of A. ferrooxidans. The more common form of rus (type-A) was found to be present in all six strains studied, including those harboring only a single copy of the gene. In addition a less common form (type-B) occurred in strains harboring multiple copies of the gene. The two genes were expressed as rusticyanin isozymes with differing surface charges due to differences in their amino acid composition. Still, the copper coordination sites were completely conserved, thereby maintaining the high redox potential necessary for an electron carrier.
Wissenschaft und Kodifikation des Privatrechts im 19. Jahrhundert, I, hg. von Helmut Coing und Walter Wilhelm (1977)

Article Wissenschaft und Kodifikation des Privatrechts im 19. Jahrhundert, I, hg. von Helmut Coing und Walter Wilhelm was published on August 1, 1977 in the journal Zeitschrift der Savigny-Stiftung für Rechtsgeschichte: Germanistische Abteilung (volume 94, issue 1).
Real-Time Sensing on Android (2014)

Modern smartphones contain many hardware and software sensors, with numerous additional sensing capabilities scheduled to be added in future iterations of the hardware and Android framework layer. This comes at no surprise as sensing is a crucial aspect of most Android applications. Unfortunately, the Android framework provides few guarantees on the delivery of sensor data to applications that require it. Similarly, the Android specification does not provide much in terms of configuration, making its programming model difficult to utilize in more traditional real-time contexts.
Output saturation characteristics of erbium-doped fiber amplifiers pumped at 975 nm (1990)

We report the signal saturation behavior of an erbium-doped fiber amplifier pumped at 975 nm. We have characterized the output saturation powers as a function of fiber length and observed that the output saturation powers peak at an optimum length close to the optimum length for small signal gain. The output saturation power is found to be higher at a signal wavelength of 1.555 μm than at 1.532 μm.
Homocyst(e)ine and arterial occlusive diseases (1994)

Homocysteine is a thiol-containing amino acid resulting from demethylation of methionine. The free and protein-bound forms of the amino acid and derived disulfides are called homocyst(e)ine [H(e)]. Multiple studies have shown elevated H(e) levels in patients with coronary, cerebrovascular, or peripheral arterial diseases; this association is frequent and independent of most other risk factors for atherosclerosis. In the 1993 Frontiers in Medicine Symposium investigators discussed the genetic, physiological, nutritional, and pharmacological mechanisms involved in the regulation of plasma H(e), the association of H(e) with arterial occlusive diseases, and the relationships of H(e) with nitric oxide and haemostasis. High plasma H(e) levels usually can be reversed with vitamin supplements. Whether vitamin supplements will affect the evolution of arterial occlusive diseases needs to be established in prospective, placebo-controlled, randomized, clinical trials.
Combinational FLt3 Ligand and Granulocyte Macrophage Colony-Stimulating Factor Treatment Promotes Enhanced Tumor Infiltration by Dendritic Cells and Antitumor CD8+ T-Cell Cross-priming but Is Ineffective as a Therapy (2006)

Abstract Dendritic cells play significant roles in the development and maintenance of antitumor immune responses. Therapeutic recruitment of dendritic cells into the tumor microenvironment has the potential to result in enhanced antitumor T-cell cross-priming against a broad array of naturally processed and presented tumor-associated antigens. We have observed that the treatment of BALB/c mice bearing syngeneic CMS4 sarcomas with the combination of recombinant Flt3 ligand and recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF) for five sequential days is sufficient to optimize the number of tumor-infiltrating dendritic cells (TIDC). However, despite the significant increase in the number of TIDCs, the therapeutic benefit of Flt3 ligand and GM-CSF treatment is minimal. Therapy-associated TIDCs do not exhibit a “suppressed” or “suppressor” phenotype in vitro, and their enhanced numbers in cytokine-treated mice were associated with increased levels of peripheral antitumor CD8+ T effector cells and with an augmented population of CD8+ tumor-infiltrating lymphocytes (TIL). These data suggest that Flt3 ligand + GM-CSF therapy of murine tumors fails at a mechanistic point that is downstream of specific T-cell priming by therapy-induced TIDCs and the recruitment of these T cells into the tumor microenvironment. Based on the enhanced infiltration of tumors by CD4+CD25+ TIL in Flt3 ligand + GM-CSF–treated mice, this could reflect the dominant influence of regulatory T cells in situ. (Cancer Res 2006; 66(9): 4895-903)
Reaching High Power Density in Multikilowatt DC–DC Converters With Galvanic Isolation (2009)

In this paper, the possibility of reaching high power densities in multikilowatt dc-dc converters with galvanic isolation is demonstrated and the main design issues are discussed. The issues related to converter topology, transformer design, and thermal management are addressed, and new conceptual solutions are proposed. Implementing zero-voltage-switching quasi-zero-current-switching topology, optimized transformer design with leakage layer, and thermal management based on conduction enhanced by heat pipes at critical places resulted in very high power density and efficiency. The power density reached by the converter prototype is 11.13 kW/L with water cooling and 6.6 kW/L with air cooling. In the same time, the measured efficiency exceeded 97% in a broad load range. The new design concepts are demonstrated on a 50-kW converter prototype that was successfully tested at full-load conditions.
Determination of Serum Cortisol by Isotope-Dilution Liquid-Chromatography Electrospray Ionization Tandem Mass Spectrometry with On-line Extraction (2001)

A liquid chromatographic-mass spectrometric method for the determination of cortisol in serum using atmospheric pressure electrospray ionization and tandem mass spectrometry is described. During sample preparation, 150 microl of serum were deproteinized with methanol/zinc sulfate followed by on-line solid phase extraction employing column switching. Tri-deuterated cortisol was used as the internal standard. The following transitions were monitored: cortisol, 363>309 m/z; d3-cortisol, 366>312 m/z. The total run-time was 5 minutes. The method proved linear (0-500 microg/l; r=0.999), precise (total coefficient of variation between 5.0% and 3.2% at a mean cortisol concentration of 15.1 microg/l and 269 microg/l, respectively; n=16) and specific with regard to relevant endogenous and exogenous steroids.
CMOS differential pass-transistor logic design (1987)

This logic technique offers greater area efficiency, higher speeds of operation, and simpler design algorithms than conventional CMOS pass-transistor logic. Experimental results and the automated techniques used in implementing efficient pass-transistor layouts are presented. The application of CMOS differential pass-transistor logic design in custom applications is also discussed.
Generation and Detection of Torsional Waves in a Rotating Shaft Using a Magnetostrictive Patch Array (2006)

A new magnetostrictive patch array transducer for the generation and detection of torsional waves is developed for the on-line health monitoring of rotating shafts. Even though the torsional wave is useful in nondestructive evaluation due to its non-dispersive property, a transducer generating torsional waves in rotating shafts has not been developed so far. In this research, a torsional wave transducer using the magnetostrictive effect is newly developed. By bonding an array of magnetostrictive rectangular patches on the outer surface of the shaft at an oblique angle of 45˚and encircling the array by a solenoid coil, we have successfully generated and measured torsional waves by the developed transducer. Several experiments were carried out to check the transducer performance.
HyperVDP: High-Performance Virtualization of the Programmable Data Plane (2019)

With the advent of P4-specific programmable data plane (PDP), network functions (NFs) can be offloaded into the PDP to achieve high performance guaranteed by hardware. Meanwhile, CPU powers consumed by NFs can be released to user applications. However, as more and more NFs can be offloaded, several problems rooted inside the PDP severely hinder it from facilitating this offloading trend. 1) The existing PDP provides the exclusive data plane abstraction where different NFs cannot operate the same data plane. 2) The PDP is hardly able to deploy NFs in a “hitless” manner. In this paper, we propose HyperVDP as a high-performance data plane hypervisor to provision non-exclusive abstraction and uninterrupted reconfigurability on the P4-specific PDP. To achieve virtualization, we design several innovative techniques to equally express functions of all programmable elements in the P4-specific PDP. We implement the prototype of HyperVDP on different target platforms, and evaluate different target-based prototypes by comparing with their counterparts. Results show that BMv2-target HyperVDP averagely prevails over its counterpart 2.5× in performance and 4× in resource efficiency. DPDK-target HyperVDP performs comparably to its counterparts while offering virtualization features which neither of its counterparts could provide.
Egg and breast milk based nitrogen sources compared. (1989)

A nitrogen source based on egg protein (Vamin 9 glucose) and an alternative with an amino acid profile more similar to breast milk (Vaminolact), were compared in 14 parenterally fed infants. Subjects were randomly allocated to receive one or other amino acid solution, but were otherwise given identical diets. At the start of the study the two groups did not differ significantly in postconceptual age, postnatal age, or weight. Over a six day study period on a stable intake of intravenous nutrients there was no significant difference in growth or nitrogen retention between the two groups. Plasma amino acid profiles in those receiving Vamin 9 glucose, however, were frequently abnormal. Notably, mean concentrations of potentially neurotoxic phenylalanine and tyrosine were significantly higher (140% and 420%, respectively) in patients fed Vamin 9 compared with those given Vaminolact. An amino acid solution based on the composition of breast milk protein therefore brings plasma amino acid profiles during parenteral nutrition closer to those found in breast fed infants, and reduces in particular, the risks of hyperphenylalaninaemia and hypertyrosinaemia.
Systems biology markup language: Level 2 and beyond (2003)

The SBML (systems biology markup language) is a standard exchange format for computational models of biochemical networks. We continue developing SBML collaboratively with the modelling community to meet their evolving needs. The recently introduced SBML Level 2 includes several enhancements to the original Level 1, and features under development for SBML Level 3 include model composition, multistate chemical species and diagrams.
Partial and Full PCR-Based Reverse Genetics Strategy for Influenza Viruses (2012)

Since 1999, plasmid-based reverse genetics (RG) systems have revolutionized the way influenza viruses are studied. However, it is not unusual to encounter cloning difficulties for one or more influenza genes while attempting to recover virus de novo. To overcome some of these shortcomings we sought to develop partial or full plasmid-free RG systems. The influenza gene of choice is assembled into a RG competent unit by virtue of overlapping PCR reactions containing a cDNA copy of the viral gene segment under the control of RNA polymerase I promoter (pol1) and termination (t1) signals - herein referred to as Flu PCR amplicons. Transfection of tissue culture cells with either HA or NA Flu PCR amplicons and 7 plasmids encoding the remaining influenza RG units, resulted in efficient virus rescue. Likewise, transfections including both HA and NA Flu PCR amplicons and 6 RG plasmids also resulted in efficient virus rescue. In addition, influenza viruses were recovered from a full set of Flu PCR amplicons without the use of plasmids.
Effect of Protease Inhibitors on Yield of HSV-1-Based Viral Vectors (2000)

The ability to obtain high titer replication-defective herpes simplex virus (HSV) recombinant vectors will dramatically affect their use in gene therapy clinical trials. A variety of techniques and reagents have been employed to increase the overall yield of the vector. The effects of protease inhibitors on the yield of an HSV-1-based viral vector were examined. Experiments were conducted using a commercial protease inhibitor cocktail typically used in mammalian cell culture for protein production. Contrary to our expectation for enhanced vector yield, the results showed a dramatic reduction in vector yield. Moreover, it was found that AEBSF is the only component in the protease cocktail responsible for the low vector yield. On the basis of our hypothesis regarding the mode of action of AEBSF, we suggest that it should not be included in protease inhibitor cocktails designed for use in cultures aimed at production of viral vectors derived from HSV-1 or possibly several other vectors.
Snapping Surfaces (2007)

A simple, robust, biomimetic responsive surface based on controlled elastic instabilities using an array of microlens shells as a surface geometry is presented. The snap-through transition is dictated by geometry, length-scale, and materials properties, thus the transition time, triggering sensitivity, and magnitude change are highly tunable. Their potential use as a rapidly switchable optical device is illustrated.
Relational Database Design And Implementation For Biodiversity Informatics (2005)

The complexity of natural history collection information and similar information within the scope of biodiversity informatics poses significant challenges for effective long term stewardship of that information in electronic form. This paper discusses the principles of good relational database design, how to apply those principles in the practical implementation of databases, and examines how good database design is essential for long term stewardship of biodiversity information. Good design and implementation principles are illustrated with examples from the realm of biodiversity information, including an examination of the costs and benefits of different ways of storing hierarchical information in relational databases. This paper also discusses typical problems present in legacy data, how they are characteristic of efforts to handle complex information in simple databases, and methods for handling those data during data migration.
Active lifetime extension &#x2014; Demonstrated for voltage source converters (2010)

Many voltage source converters have no redundant power components (e.g. IGBT modules) built in. Therefore if one power component fails, the converter stops working. Here we introduce a generic approach that takes advantage of the inherent redundancies of voltage vectors in multilevel converters in order to actively extend the lifetime of converters. When detecting increased stress of one IGBT module, the switching strategy is altered in order to reduce the load of that particular IGBT module. The active lifetime extension (ALE) switching strategy aims to balance the remaining life of all IGBT modules at all times. In such way the lifetime of the converter is maximized.