gebhart/patrepeval huggingface dataset:
Screening Rose Clover and Subterranean Clover Germplasm for Isoflavones (1991)

Subterranean clovers ( Trifolium brachycalycinum Katzn. and Morley, T. subterraneum L., and T. yanninicum Katzn. & Morley) contain phytoestrogenic isoflavones. High levels of these compounds are responsible for sheep ( Ovis aries ) reproductive disorders. Our objective was to screen the available subterranean and rose clover ( T. hirtum All.) germplasm from the USDA Plant Introduction collection for isoflavone content. Clover plants were grown in the greenhouse and sampled when the seedlings were 42‐d old. Leaves were extracted with methanol (7 d at 5 °C) and analyzed using highperformance liquid chromatography techniques. Isoflavones were very low (<0.2 g kg −1 ) or not detectable in rose clover. Total isoflavone levels in subterranean clover ranged from 0.1 to 18.5 g kg −1 . The information generated in this study will aid in identification of subterranean clover lines with low isoflavone traits.
Propranolol for airway hemangiomas: Case report of novel treatment (2009)

Infantile hemangiomas arising in the trachea are rare. These lesions pose a management dilemma as several treatment options can provide safe management. Propranolol, a nonselective beta-blocker, has recently been introduced as a novel modality for the treatment of proliferating hemangiomas. This report illustrates the successful management of tracheal hemangiomas using oral propranolol in a young patient with otherwise treatment-resistant airway lesions. Despite various endoscopic therapeutic attempts, the patient remained stridulous with airway disease that persisted into the involution phase of the average hemangioma cycle. Within 6 weeks of beginning oral propranolol (2 mg/kg/day), her airway compromise was eliminated and she had complete resolution of endoscopically visible disease. No side effects from propranolol occurred. We propose that oral propranolol should be considered for use in airway hemangiomas.
Detection of focal liver lesions: CT of the hepatobiliary system with gadoxetic acid disodium, or Gd-EOB-DTPA. (1997)

Patient tolerance of gadoxetic acid disodium was acceptable, and liver enhancement and visualization of liver lesions and the biliary system was improved at CT.
In vivo autofluorescence investigations on animal tumors. (1989)

The in vivo fluorescence behavior of unmarked tissue (autofluorescence) of tumor-bearing mice was investigated. An argon-ion laser was used as the excitation source emitting radiation at 351 nm and 364 nn. Fluorescence bands in the red spectral range were recorded. The spectral distribution of the fluorescence of the solid Ehrlich carcinoma was different from that of the neighboring tissue.
Strontium and Actinide Removal Testing with Monosodium Titanate and Other Sorbents (2002)

SRTC researchers examined the affects of solution phase composition, the oxidation state of plutonium and neptunium and different production batches on the performance of monosodium titanate (MST) to remove strontium and actinides from alkaline salt solutions. Testing also evaluated the performance of alternate sorbents including sodium nonatitanate (ST), crystalline silicotitanate and pharamacosiderite materials.
GADD153/CHOP, a DNA damage-inducible protein, reduced CAAT/enhancer binding protein activities and increased apoptosis in 32D c13 myeloid cells. (1996)

GADD153/CHOP is a DNA damage-inducible, nuclear leucine zipper protein that is capable of producing a G1-S arrest in fibroblastic cells and of dimerizing with and inhibiting CAAT/enhancer binding protein (C/EBP) activities. CHOP was induced in 32D cl3 myeloid cells exposed to methylmethane sulfonate (MMS), a DNA alkylating agent. The degree of induction was dependent upon the dose of MMS to which the cells were exposed. CHOP was not expressed, at least at similar levels, during 32D cl3 cell granulocytic differentiation or during their apoptosis upon growth factor withdrawal. High-level expression of exogenous CHOP in 32D cl3 cells markedly inhibited the trans-activation activities of endogenous C/EBPs. These cells proliferated in IL-3, although low-level ongoing apoptosis not observed with control cells was detected. When these cultures were transferred to granulocyte colony-stimulating factor (G-CSF), the majority of the cells underwent apoptosis, although the levels of CHOP did not increase. Similarly, 32D cl3 cells treated with doses of MMS sufficient to induce endogenous CHOP underwent apoptosis more rapidly when placed in G-CSF-containing, compared with interleukin 3 (IL-3)-containing, medium. However, induction of CHOP by MMS was similar in IL-3 and in G-CSF. The heightened sensitivity of 32D l13 cells to CHOP in G-CSF could result either from the loss of IL-3-specific signals or from increased expression of C/EBPs. Because myeloid leukemias express C/EBPalpha, induction of CHOP might contribute to their chemotherapy-induced apoptosis, and alterations in CHOP expression could contribute to their development of chemotherapy resistance.
A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study (2017)

This data shows that acute administration of CBD reduces resting BP and the BP increase to stress in humans, associated with increased HR. These hemodynamic changes should be considered for people taking CBD. Further research is required to establish whether CBD has a role in the treatment of cardiovascular disorders.
Beamforming Transmission in IEEE 802.11ac under Time-Varying Channels (2014)

The IEEE 802.11ac wireless local area network (WLAN) standard has adopted beamforming (BF) schemes to improve spectral efficiency and throughput with multiple antennas. To design the transmit beam, a channel sounding process to feedback channel state information (CSI) is required. Due to sounding overhead, throughput increases with the amount of transmit data under static channels. Under practical channel conditions with mobility, however, the mismatch between the transmit beam and the channel at transmission time causes performance loss when transmission duration after channel sounding is too long. When the fading rate, payload size, and operating signal-to-noise ratio are given, the optimal transmission duration (i.e., packet length) can be determined to maximize throughput. The relationship between packet length and throughput is also investigated for single-user and multiuser BF modes.
Psychosocial Impact of Hidradenitis Suppurativa: A Qualitative Study (2011)

Hidradenitis suppurativa influences patients' lives in many ways. It is therefore necessary to focus on the effects of the disease on daily life in order better to define patient-related outcomes in hidradenitis suppurativa studies. Interviews were conducted with 12 patients with hidradenitis suppurativa. Initial single interviews were followed by semi-structured and structured qualitative focus group interviews in order to improve the richness of the data and obtain in-depth understanding of the impact of the topics. Important topics were found to relate to aspects of interpersonal contact, especially in relation to smell and appearance, various emotional reactions, and feelings of lack of control. It was found that hidradenitis suppurativa has a great emotional impact on patients and promotes isolation due to fear of stigmatization. Shame and irritation are frequent and relate to smell, scars, itching and pain. Quality of life is adversely affected and professional support is needed.
[Radiologic detection of triombrast in liposomes of liver and spleen (first phase of clinical trial)]. (1995)

Clinical trials of the liposomal form of water-soluble x-ray contrast agent triombrast (90 mg of iodine in 1 ml) was carried out in 23 patients with Hodgkin's disease, 9 with liver cirrhosis, and 6 with malignant tumors of different localizations. Distinct images of the liver and spleen appeared 2-2.5 h after intravenous injection of the formulation. They could be observed during 4-6 h by plane radiography. Liposomal hepatolienography permits identification of the structural alteration sites 0.8-1.0 cm in size in these organs. Administration of higher doses of the formulation (more that 0.5 ml/kg) was associated with such side effects as fever and hyperthermia in 30% of patients parallel with the side effects common for iodine-containing x-ray contrast agents. These side effects could be eliminated by previous administration of prednisolone and pipolphen. These side effects were not observed after injection of lower doses of the formulation (less than 0.5 ml/kg) sufficient for an essential improvement of the image contrast during computer-aided tomography.
Separating and tracking multiple beacon sources for deep space optical communications (2010)

We propose a solution for pointing and tracking an optical terminal using one or more beacons and a slowly varying background image. The primary application is a deep space optical communication terminal, where multiple source tracking provides robustness against beacon outage. Our solution uses optical orthogonal codes modulated on each beacon to separate the signal from each source for centroiding. This technique allows calculation of the transmit pointing vector from each beacon location as well as from the background image. The latter can be used to track during beacon outages. We present a simple algorithm for performing this separation, and apply it to experimental data from a photon-counting detector illuminated by two beacons and one constant source. Our results show that the photon flux from each source can be accurately estimated even in the low signal, high background regime. We estimate the variance of the signal estimator due to Poisson fluctuations and infer the effect on a centroid estimator for tracking.
New Family of Trisiloxane Surfactants (2006)

Abstract The interfacial properties of a series of novel aqueous trisiloxane of the general formula Me 3 SiOSiMeROSiMe 3 [R=(CH 2 ) 3 N(CH 2 CH(OH)CH 2 (OCH 2 CH 2 ) n OCH 3 ) 2 n=1,2] were studied. The physicochemical parameters of these trisiloxane were discussed. These surfactants reduced the equilibrium surface tension of water to a minimum value of approximate 21∼22 mN/m at concentration levels of 10 −4 mol·L −1 .
Construction of an Hfr strain useful for transferring recA mutations between Escherichia coli strains (1980)

Strain JC10240 (Hfr PO45 srlC300::Tn10 recA56 thr-300 ilv-318 rpsE300) was constructed. On account of the close linkage of Tn10 to recA56, the latter can be moved to other Escherichia coli (and closely related) strains in transductional or conjugational crosses selecting resistance to tetracycline.
Nanoaperture-Enhanced Signal-to-Noise Ratio in Fluorescence Correlation Spectroscopy (2008)

The fluorescence enhancement found in gold nanoapertures is demonstrated to increase the signal-to-noise ratio (SNR) in fluorescence correlation spectroscopy (FCS). Starting from a general discussion on noise in FCS experiments, we show that fluorescence enhancement leads to a dramatic increase in the SNR. This prediction is confirmed by experiments where we report an experimental gain in SNR of about 1 order of magnitude, corresponding to a 100-fold reduction of the experiment duration. This technique is then applied to monitor the kinetics of a fast enzymatic cleavage reaction. This set of experiments evidence the feasibility of FCS analysis with fast integration times of about 1 s, opening the way to the monitoring of a variety of biochemical reactions at reduced time scales.
The Association Between PD-L1 Expression and the Clinical Outcomes to Vascular Endothelial Growth Factor-Targeted Therapy in Patients With Metastatic Clear Cell Renal Cell Carcinoma (2015)

Vascular endothelial growth factor pathway (VEGF)-tyrosine kinase inhibitors (TKIs) are essential for the treatment of metastatic renal cell carcinoma patients, but the treatment suffers from a lack of predictive markers. This study demonstrates that PD-L1 expression is a predictor for unfavorable response to VEGF-TKI and a prognostic indicator for poor overall survival and progression-free survival in patients with metastatic clear cell renal cell carcinoma receiving VEGF-TKI.
Hyporheic zone denitrification: Controls on effective reaction depth and contribution to whole-stream mass balance (2013)

Stream denitrification is thought to be enhanced by hyporheic transport but there is little direct evidence from the field. To investigate at a field site, we injected 15 NO 3 , Br (conservative tracer), and SF 6 (gas exchange tracer) and compared measured whole-stream denitrification with in situ hyporheic denitrification in shallow and deeper flow paths of contrasting geomorphic units. Hyporheic denitrification accounted for between 1 and 200% of whole-stream denitrification. The reaction rate constant was positively related to hyporheic exchange rate (greater substrate delivery), concentrations of substrates DOC and nitrate, microbial denitrifier abundance (nirS), and measures of granular surface area and presence of anoxic microzones. The dimensionless product of the reaction rate constant and hyporheic residence time, hz hz define a Damkhler number, Da den-hz that was optimal in the subset of hyporheic flow paths where Da den-hz % 1. Optimal conditions exclude inefficient deep pathways where substrates are used up and also exclude inefficient shallow pathways that require repeated hyporheic entries and exits to complete the reaction. The whole-stream reaction significance, R s (dimensionless), was quantified by multiplying Da den-hz by the proportion of stream discharge passing through the hyporheic zone. Together these two dimensionless metrics, one flow-path scale and the other reach-scale, quantify the whole-stream significance of hyporheic denitrification. One consequence is that the effective zone of significant denitrification often differs from the full depth of the hyporheic zone, which is one reason why whole-stream denitrification rates have not previously been explained based on total hyporheic-zone metrics such as hyporheic-zone size or residence time.
An 8&#x2013;16 Gb/s, 0.65&#x2013;1.05 pJ/b, Voltage-Mode Transmitter With Analog Impedance Modulation Equalization and Sub-3 ns Power-State Transitioning (2014)

Serial link transmitters which efficiently incorporate equalization, while also enabling fast power-state transitioning to leverage dynamic power scaling, are necessary to meet future systems' I/O requirements. This paper presents a scalable voltage-mode transmitter which offers low static power dissipation and adopts an impedance-modulated 2-tap equalizer with analog tap control, thereby obviating driver segmentation and reducing pre-driver complexity and dynamic power. Topologies that allow for rapid power-up/down, including a replica-biased voltage regulator to power the output stages of multiple transmit channels and per-channel quadrature clock generation with injection-locked oscillators (ILO), enable fast power-state transitioning. Energy efficiency is further improved with capacitively driven low-swing global clock distribution and supply scaling at lower data rates, while output eye quality is maintained at low voltages with automatic phase calibration of the local ILO-generated quarter-rate clocks. A prototype fabricated in a general purpose 65 nm CMOS process includes a 2 mm global clock distribution network and two transmitters that support an output swing range of 100–300 mV <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$_{\rm ppd}$</tex></formula> with up to 12 dB of equalization. The transmitters achieve 8–16 Gb/s operation at 0.65–1.05 pJ/b energy efficiency and sub-3 ns power-up/down times.
Non-steroidal Anti-inflammatory Drug Use and the Risk of Gastric Cancer: A Systematic Review and Meta-analysis (2003)

NSAID use was associated with a decreased risk of gastric cancer in a dose-dependent manner. This finding warrants proper clinical trials in populations with high risk of gastric cancer.
Triggering of neoplastic B cells <i>via</i> surface IgM and the cell surface antigens CD20 and CDw40. Responses differ from normal blood B cells and are restricted to certain morphologic subsets (1988)

By raising monoclonal antibodies (MAbs) against B cells, a number of cell surface molecules have recently been identified which after binding by their specific antibody can trigger B cells, either alone or in co-operation with antibodies to surface immunoglobulin (sIg). The anti-CD20 (Bp35) MAb IF5 can deliver a strong activation signal to resting normal B cells, and the anti-CDw40 (Bp50) MAb G28-5 can promote activated G1 B cells to enter S phase. These antibodies were tested for their functional effects in vitro on suspended cells from 17 follicle-center-cell (FCC) lymphomas, 5 cases of chronic lymphatic B-cell leukemia (B-CLL) and 8 cases of various histological types. Changes in cellular volume, RNA and DNA synthesis were compared with the results obtained with a polyclonal anti-mu [F(ab')2] antiserum, a MAb to surface IgM (AF6), 12-O-tetradecanoyl-phorbol-13-acetate (TPA) and B-cell growth factor (low-molecular-weight BCGF). Our data reveal differences in the requirements for triggering of various B-cell subsets: cells from CLL responded strongly to TPA but not to anti-mu, which is a potent stimulator not only of normal B cells but also of cells from individual cases of FCC lymphomas. Our observations suggest that the differentiation stage of B-CLL cells is distinct from that of small resting B cells from peripheral blood. Centrocytic lymphomas could not be activated by any of the reagents. CD20-mediated triggering was seen in neoplastic B cells from only 4 of 30 cases, indicating that most B-cell neoplasias were not responsive to this activation pathway. In contrast, the anti-CDw40 MAb consistently stimulated DNA synthesis together with anti-mu or TPA in cells from FCC lymphomas, but not from CLL. Together, these results suggest that activation in different neoplastic B-cell subsets depends on distinct signal transduction mechanisms.
Improved offset-compensation schemes for switched-capacitor circuits (1984)

Novel switched-capacitor stages which are free from the effects of op-amp DC offset voltage are described. The op-amps used in the stage need not slew between the desired output voltage and the offset voltage as in previously described offset-free circuits. The use of the new scheme in general applications is also discussed.
Three Dimensional Graphene Foam/Polymer Hybrid as a High Strength Biocompatible Scaffold (2015)

Graphene foam (GrF)/polylactic acid–poly‐ε‐caprolactone copolymer (PLC) hybrid (GrF‐PLC) scaffold is synthesized in order to utilize both the desirable properties of graphene and that of foams such as excellent structural characteristics and a networked 3‐D structure for cells to proliferate in. The hybrid scaffold is synthesized by a dip‐coating method that enables retention of the porous 3D structure. The excellent wettability of PLC with graphene foam along with the formation of PLC bridges leads to a ≈3700% enhancement in strength and a ≈3100% increase in ductility in the GrF‐PLC scaffold. Biocompatibility of both graphene foam and GrF‐PLC scaffold is demonstrated by culturing of human mesenchymal stem cells (hMSCs) for 28 days, a period over which cell proliferation is robust. The hMSCs are differentiated in chondrogenic media and supported chondrogenesis in both scaffolds. The demand for aggrecan extracellular matrix protein synthesis is reduced in hybrids due to improved bearing of cell‐induced loads, this may be critical for ensuring adequate cellular distribution and layering of extracellular matrix. Hence, the unique mechanical and biotolerant properties of the GrF‐PLC scaffold are suited for musculoskeletal tissue engineering applications, such as the growth of de novo cartilage to replace cartilage lost due to injury or osteoarthritis.
Metastatic Melanoma: Chemotherapy to Biochemotherapy (2002)

Biochemotherapy remains a promising new treatment for metastatic melanoma. A large Intergroup trial E3695 comparing concurrent biochemotherapy to combination chemotherapy alone is powered to answer important survival questions.
Developing PowerBuilder 5 Applications with CD (1996)

From the Publisher:
Capitalizing on the success of the previous edition, Developing PowerBuilder 5 Applications, Fourth Edition is a hands-on guide for developer's that want to create their own real-world applications. It details all the new changes to PowerBuilder, giving the programmer the essential information they need to exploit PowerBuilder 5's powerful features.
Teaches how to exploit PowerBuilder 5's new features
Programmers will master user interface design, PowerScript programming, debugging, and database design
CD-ROM includes all the source code from the book and various PowerBuilder applications
Superbases as powerful tools in organic syntheses (1992)

A review with 136 refs. on the use of organometallic and other superbases in org. synthesis. [on SciFinder (R)]
Blood cell growth factors: Their biology and clinical applications (1990)

Journal Article Blood cell growth factors: Their biology and clinical applications Get access Martin J. Murphy, Jr Martin J. Murphy, Jr Hipple Cancer Research Center, Dayton, Ohio, USA Correspondence: Dr. Martin J. Murphy, Jr., Hipple Cancer Research Center, 4100 South Kettering Boulevard, Dayton, OH 45439–2092, USA. Search for other works by this author on: Oxford Academic Google Scholar The International Journal Of Cell Cloning, Volume 8, Issue 2, 1990, Pages 138–145, https://doi.org/10.1002/stem.5530080207 Published: 01 January 1996 Article history Received: 25 January 1990 Published: 01 January 1996
The Effect of Dietary Protein Restriction on the Progression of Diabetic and Nondiabetic Renal Diseases (1996)

Dietary protein restriction effectively slows the progression of both diabetic and nondiabetic renal diseases.
Challenges in atomic layer deposition of carbon-containing silicon-based dielectrics (2017)

The authors have designed experiments to test three different approaches for the incorporation of carbon atoms into amorphous SiNx or SiO2 films grown using atomic layer deposition (ALD). In each approach, the surface reactions of the precursors were monitored in situ using attenuated total reflection Fourier transform infrared spectroscopy. In the first approach, for depositing carbon-containing SiNx films using ALD, carbon was introduced into the process through a silicon precursor, SiCl2(CH3)2, followed by NH3 plasma exposure. While our infrared data show that SiCl2(CH3)2 reacts with an –NHx (x = 1, 2) terminated surface created after NH3 plasma exposure, –CH3 groups are eliminated in the precursor adsorption step leading to no significant carbon in the films. In the second approach, the authors hypothesized a three-step ALD process, which would involve Si-, C-, and N-containing precursors, and tested the reactivity of two carbon-containing precursors, CH3I and Al(CH3)3, with H- and Cl-terminated silicon surfaces, respectively. The authors show that both precursors readily react with the silicon surfaces, but neither one provides the appropriate surface termination. CH3I reacts with surface –SiHx (x = 1, 2, 3) to create surface –SiIx (x = 1, 2, 3) species with CH3 as the leaving groups. While Al(CH3)3 reacts with the Cl-terminated Si surface to form a surface –SiCH3 group, residual aluminum remains on the surface as –Al(CH3)x (x = 1, 2) groups that are not completely removed as volatile Al(CH3)xCl3−x (x = 1, 2). Finally, in the third approach for ALD of carbon-containing SiO2 films, the authors used Si2Cl6 with CO and CO/O2 plasmas. A pure CO plasma led to amorphous carbon growth, and a CO plasma diluted with of O2 led to no detectable carbon incorporation in the SiO2 film.