gebhart/patrepeval huggingface dataset:
Flow cytometric screening of blood samples for malaria parasites (1993)

An automated method for the detection and estimation of malaria parasites in blood samples using flow cytometry is presented. In a single-step procedure 50 microliters of blood sample was collected in 1 ml of lysis solution containing formaldehyde, causing red blood cells to lyse while parasites and white blood cells are preserved. Thus prepared, samples could be transported and remained stored in lysis solution until flow cytometric analysis was performed. The cells were stained for DNA with the fluorescent dye Hoechst 33258 and subsequently analyzed by a FACStar flow cytometer. Parasites and white blood cells were distinguished and counted based on blue Hoechst fluorescence and forward scattering. Since red blood cells were lysed, parasite numbers were given related to the number of white blood cells similar to what is done in microscopic examination of thick blood smears. In dilution experiments with animal and human material, parasite counts by flow cytometry correlated very well with the theoretically calculated numbers (regression coefficients of > 0.94). In human material parasitemias of approximately 0.005% were detected. In a pilot study, 700 samples were collected in Thailand and screened by microscopic examination of thick smears and by flow cytometry; 29 were found positive by combining both methods, 2 were missed by flow cytometry, and 20 were missed by microscopists in the field. After microscopic reexamination in the central laboratory, 15 of these 20 were found positive, 5 remained unconfirmed.
Multiscale DSA simulations for efficient hotspot analysis (2014)

In this study, we have investigated how to link ”large-scale simulations with the simplified models” to ”mesoscale simulations with the detailed models.” For the simplified model, we have applied so-called the generalized Ohta-Kawasaki (gOK) model. Our simulation flow was implemented by two steps: 1) parallel computations of block copolymer annealing with the simplified model, 2) detailed analysis of the defects with the SCFT. The local volumetric densities of block copolymers calculated by the simplified models were used as an input for the SCFT. Then the SCFT simulations were performed under the constraints in which the density field was driven to be the one obtained from the simplified model. Using the resultant partition functions, we were able to obtain spatial distributions of the free chain ends and the connection points of the blocks. Note that the chain conformation of block copolymer is an important, but missing component of the simplified models; this multi-scale approach is expected to be useful for further understanding the origin and stability of DSA defects.
Recrystallization creep of sodium chloride in solutions with different compositions: 2. The effect of urea additives (2008)

The study of the recrystallization creep of sodium chloride crystals shows that, beginning with a concentration of 10−2 M, the addition of urea to a solution noticeably decelerates the recrystallization creep of NaCl. It is proven that the deceleration of the creep is due to the passage of the process from a diffusion regime to a kinetic one, which is limited by the rate of salt dissolution.
The Japanese translation of Chuck Palahniuk's Lullaby an examination of some translation strategies and choices (2009)

An analysis of the translation strategies evident from a textual comparison of Chuck Palahniuk’s Lullaby with the Japanese translation by Mariko Ikeda. Comparison with translations facing similar issues and reference to translator interviews indicate that business pressures for quick translations influence the translator. Economic and time pressures may account for decided differences in style. Differences in tone are particularly noticeable in both biological terms for invasive species and unique terms created by the author. In spite of the need for a fast, profitable translation the Japanese version of Lullaby may satisfy certain ethical considerations.
Distributed network design for time-domain specifications (1971)

This correspondence describes a computer-aided design technique for designing an active distributed <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">RC</tex> network with an impulse response thai is closest to a specified time function in <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">L_{2}</tex> space. The Ghausi-Bello procedure is used to derive the network structure and initial parameter values. For optimization the gradient is computed by the adjoint network method after being extended to include distributed parameters.
Introduction (2017)

« Les villes ne sont que du temps pétrifié ».J.-C. Perrot Depuis le XIXe siècle, le centre historique de Milan a subi de nombreuses transformations : percée de la via Dante et de la galerie Vittorio Emanuele, élargissement des principaux corsi, couverture des navigli, reconstruction de certains quartiers suite aux bombardements de la Seconde Guerre mondiale, ouverture du corso Europa dans les années 1950. Ces diverses interventions ont modifié le tissu urbain dans les zones les plus centrales...
Benefits of Rehabilitation With Implants in Masticatory Function: Is Patient Perception of Change in Accordance With the Real Improvement? (2014)

This study aimed to compare the index of satisfaction and masticatory function of edentulous patients before and after rehabilitation and to evaluate if patients' perception of the changes in their oral health status is in agreement with the results of masticatory performance test. Fourteen edentulous patients were rehabilitated with lower implant-supported fixed prosthesis and upper removable dentures. Index of satisfaction and masticatory capacity (subjective analysis) and performance test (objective analysis) were evaluated before and 20 days and 8 months after rehabilitation. The patients were asked to respond a yes/no masticatory capacity questionnaire and to rate their oral satisfaction on a 0 to 10 Visual Analogue Scale (VAS). Masticatory performance test comprised the ability of the individual to pulverize an artificial test food (Optocal), after 20 and 40 masticatory strokes. When baseline answers were compared to answers 8 months after treatment, all questions, excepting the ones that considered pain and social disability, were statistically different. Wilcoxon test was used to compare index of satisfaction before and after treatment. All answers showed statistically significant differences, excluding the one that referred to ease of cleaning the prostheses. Considering the masticatory performance test, Student t test (normally distributed) and Wilcoxon test (non-normally distributed) were used to test the null hypothesis that the weight of the particles of the test food left in sieves were equal in all times of evaluation. In the larger sieve with 20 cycles, statistically significant differences were observed between baseline and 8 months, 20 days and 8 months. With 40 strokes, baseline and 20 days, baseline and 8 months and 20 days and 8 months showed significant differences. It was concluded that oral rehabilitation leads to better masticatory function in edentulous patients and there is a coincidence between patient perception and real improvement on masticatory function.
Biosynthesis of saxitoxin analogs: the unexpected pathway (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBiosynthesis of saxitoxin analogs: the unexpected pathwayYuzuru Shimizu, Manuel Norte, Akira Hori, Almoursi Genenah, and Masaru KobayashiCite this: J. Am. Chem. Soc. 1984, 106, 21, 6433–6434Publication Date (Print):October 1, 1984Publication History Published online1 May 2002Published inissue 1 October 1984https://pubs.acs.org/doi/10.1021/ja00333a062https://doi.org/10.1021/ja00333a062research-articleACS PublicationsRequest reuse permissionsArticle Views631Altmetric-Citations81LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Spin trapping of radicals generated in the UV photolysis of alkyl disulfides (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpin trapping of radicals generated in the UV photolysis of alkyl disulfidesAvinash Joshi and George C. YangCite this: J. Org. Chem. 1981, 46, 18, 3736–3738Publication Date (Print):August 1, 1981Publication History Published online1 May 2002Published inissue 1 August 1981https://pubs.acs.org/doi/10.1021/jo00331a035https://doi.org/10.1021/jo00331a035research-articleACS PublicationsRequest reuse permissionsArticle Views140Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Impact of fungal pigments (Carotenoids) in feed for Cyprinus carpio fish (KOI KARP) (2017)

The bright colours of ornamental fish are not just attractive, but have antioxidant and photoprotective functions. These colours are due to carotenoids present in the fish skin. However the fish cannot synthesize these pigments and thus depend on exogenous sources. Apart from rendering bright colours, these pigments have antioxidant, antimicrobial and photoprotective function. Pigmentation in ornamental fish increases their market value. In this study, carotenoid pigments were isolated from Penicillium purpurogenum and Talaromyces purpurogenum, used to make top coated fish feed and fed to Golden Koi (Cyprinus carpio) fish to check for enhancement in colour and other properties. The study indicated that the pigments were non - toxic to the fish, increased the fish weight and protein content and showed an enhancement in the skin color. High resolution liquid chromatography mass spectrometry data showed the presence of an additional carotenoid astaxanthin in the test fish. Thus the fungal pigment fed to the fish enhanced its colour and other properties.
Admission Control for Non-preprovisioned Service Flow in Wireless Metropolitan Area Networks (2007)

Improving the admission control process in wireless metropolitan area networks (WMAN) based on the IEEE 802.16e standard can improve the QoS. Because IEEE 802.16e supports five classes of service as well as mobility, an admission control policy for non-preprovisioned service flow is proposed. This policy is compatible with the QoS parameters for each service class defined in the standard. As improvements, the guard channel scheme is used to give handover connections higher priority and a novel proportional bandwidth-borrowing scheme is added to prioritize the different service classes. The simulation results show the proposed admission control policy maximizes the bandwidth utilization and the use of the two schemes provides a reasonable priority order of new originated connections and handover connections of different service classes. The connection-blocking and connection-dropping probabilities were reduced to the extent that they can be ignored
The string-to-string correction problem with block moves (1984)

The string-to-string correction problem is to find a minimal sequence of edit operations for changing a given string into another given string. Extant algorithms compute a longest common subsequence (LCS) of the two strings and then regard the characters not included in the LCS as the differences. However, an LCS does not necessarily include all possible matches, and therefore does not produce the shortest edit sequence.
Synthesis of Unsymmetrical 1,1′-Disubstituted Bis(1,2,3-triazole)s Using Monosilylbutadiynes (2011)

Bis(1,2,3-triazole)s have attracted recent interest as coordinating ligands for transition metals. Here we report a rapid, modular method for the synthesis of 1,1'-disubstituted-4,4'-linked unsymmetrical bis(1,2,3-triazole)s. The method employs sequential copper catalyzed azide-alkyne cycloaddition and deprotection steps on a monosilylbutadiyne. TMS (trimethylsilyl) and TIPS (triisopropylsilyl) were both investigated with TIPS being the preferred protecting group due to increased stability. The reactions were amenable to one-pot synthesis, and an optimized one-pot, three-step procedure was developed.
On a small collection of opisthobranch molluscs from Minorca (Balearic Islands, Spain) (1986)

Se citan trece especies de moluscos opistobranquios de la costa oriental de Menorca (islas Baleares). Una de ellas. Phyllidia pulitzeri Pruvot-Fol. 1962. se comenta con mayor detalle.
Magnetization Creep in Nickel-Iron Films via the Lever Mechanism (1966)

Nickel-iron films exhibit creep in a combination longitudinal dc and transverse ac field. It has been found experimentally that the creep threshold curve is not fixed in field space like the rotational switching curve, but can be displaced along the transverse field direction by an amount equal to an extra transverse dc bias field. Thus the creep threshold is a function of only the oscillating component of the transverse field. The dc component of the transverse field can be increased with little change in the shape of the creep threshold curve until the creep threshold coincides with the switching threshold curve. This has been found so far to hold for films up to 10 800 A thick. These results can be explained by a simple theory based on the ``lever'' mechanism for creep proposed last year: The additional field which causes creep originates from the induced magnetic charge on the wall due to the applied fields rotating the parallel and antiparallel domains through different angles. This theory predicts creep threshold curves which coincide with the experimental curves. The lever mechanism is unique among proposed creep models in explaining this transverse displacement of the creep threshold.
Noise in laser recording (1971)

Noise in laser recording is treated from the viewpoint of measurement techniques, equipment design, film choice, and laser power. Signal-to-noise criterions that have been found useful in specifying wide-band magnetic recorders are presented to aid in establishing noise performance parameters for laser recorders. It is shown that such equipment can be built so that it will have an insignificant effect on total noise performance and that, although film granularity is the ultimate limit on noise, improvements in SNR are a function of increased laser power. The design of a 100-MHz analog laser signal recorder is used as the basis for discussion; however, the theory and techniques apply to all forms of laser recording.
Control of cracks by interfaces in composites (1975)

Abstract A novel theory is proposed to show how a crack may he accelerated or retarded when it meets an interface between two equally brittle materials of different elastic properties. Measurements of a model crack travelling through a brittle adhesive joint have substantially verified the theory. The results demonstrate that the toughness of a composite material, having a periodic stiffness change along the crack path, may be very much greater than the toughness of the individual components of the composite. The relevance of these ideas to the design of tough composite structures is discussed.
1,3‐Dipolar Cycloaddition of Ethyl Propiolate to 4,4‐Dimethyl‐4,5‐dihydro‐1,2‐dithiolo[5,4‐c]quinoline‐1‐thiones. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Cytomegalovirus Replication in Cells Pretreated with 5-Iodo-2′-Deoxyuridine (1973)

The replication of human cytomegalovirus (CMV) in cells pretreated with 5-iodo-2'-deoxyuridine (IUdR) was studied. Pretreatment of cells with IUdR enhanced several parameters of virus replication. Virus grown in drug-treated cells exhibited a shorter eclipse period and the cells produced more infectious virus sooner than did untreated cells. There was an approximate fivefold increase in virus yield per cell in the drug-treated samples when compared to control cultures. The time required for plaque development was shortened by 6 days in drug-treated cultures. Pretreatment of cells with IUdR also increased plaquing efficiency of the virus by approximately 10-fold. The enhancement of virus replication by IUdR was further demonstrated by varying the multiplicity of infection. In a 7-day period there was a 100-fold increase in sensitivity of the cultures for virus detection when the cells had been previously exposed to IUdR. The data presented indicate the possibility that IUdR interferes with the production of a cellular product inhibitory for CMV replication.
Metal/ferroelectric/insulator/semiconductor structure of Pt/SrBi2Ta2O9/YMnO3/Si using YMnO3 as the buffer layer (1999)

The ferroelectric SrBi2Ta2O9 (SBT) and YMnO3 buffer layers for the metal/ferroelectric/ insulator/semiconductor (MFIS) structure were deposited using pulsed-laser ablation and metalorganic chemical vapor deposition, respectively. Memory windows of the MFIS structure were in the range of 0.3–1.5 V when the gate voltage varied from 2 to 6 V. There were no reactions between ferroelectric SBT and Si in the MFIS structure annealed at 900 °C. The YMnO3 buffer layer plays an important role in alleviating the interdiffusion between elements of SBT and Si. The proposed MFIS structure of Pt/200 nm–SBT/25 nm–YMnO3/Si is attractive for nondestructive read-out ferroelectric random access memory applications.
Note: An adhesion measurement setup for bioinspired fibrillar surfaces using flat probes (2012)

Current adhesion measurement setups designed for experiments on bioinspired fibrillar surfaces, either commercial or constructed in-house, do not allow adhesion measurements with in situ visualization, high resolution, high force range, and controlled alignment at the same time. In this paper a new adhesion tester is presented, which enables contact experiments with controlled tilt angle (accuracy of ±0.02°). This allows the use of flat probes and thus greatly simplifies the determination of experimental parameters such as pull-off strength or Young's modulus. The deflection of a double-clamped glass beam is measured by laser interferometry with an accuracy of ±60 nm, which yields a precise force measurement over three orders of magnitude force range without changing the glass beam. Contact formation and detachment events can be visualized in situ. The current adhesion tester is designed for force measurements in the range of 1 μN to 1 N and fills the gap between macroscopic tests and atomic force microscopy measurements.
C1‐TEN is a negative regulator of the Akt/PKB signal transduction pathway and inhibits cell survival, proliferation, and migration (2005)

We have previously identified C1 domain-containing phosphatase and TENsin homologue (C1-TEN) as being an intracellular binding partner for Axl receptor tyrosine kinase (RTK). C1-TEN is a tensin-related protein that houses an N-terminal region with predicted structural similarity to PTEN. Here, we report our observations on the effects of ectopic expression of C1-TEN in HEK293 cells, which resulted in profound molecular and phenotypic changes. Stable expression of C1-TEN altered cellular morphology, with less cell spreading and weaker filamentous actin staining. Cells overexpressing C1-TEN were inhibited greatly in their proliferation and migration rates as compared with mock-transfected cells. Furthermore, serum starvation-induced apoptosis caused a twofold increase in caspase 3 activity in C1-TEN-overexpressing cells vs. mock cells. In addition, C1-TEN-overexpressing cells showed a markedly reduced phosphorylation of Akt/PKB kinase and its substrate GSK3, as well as reduced Akt enzymatic activity. No such effects on JNK were observed. Also, serum-stimulated activation of Akt was delayed in C1-TEN-overexpressing cells, while no difference in profile of ERK activation was observed. Furthermore, cells expressing a C1-TEN mutant where the putative phosphatase active site cysteine at position 231 was substituted for a serine displayed full restoration of both cell proliferation and Akt activation. In conclusion, C1-TEN appears to be a novel intracellular phosphatase that negatively regulates the Akt/PKB signaling cascade, and is similar to its relative PTEN in this respect. However, the particular domain organization of C1-TEN may enable it to regulate RTK and other signaling complexes that are linked to Akt/PKB signaling in a unique manner.
A programmed controlled temperature microscope stage (1978)

SUMMARY The construction, and testing, of a programmed controlled temperature stage for optical microscopy is described. The stage is shown to be capable of attaining temperatures between 160 K and 373 K, and of providing repeatable heating and cooling rates up to, and in excess of 100 K min −1 . It is also capable of providing stable temperature holds.
Activation of M-phase-specific histone H1 kinase by modification of the phosphorylation of its p34cdc2 and cyclin components. (1990)

An M-phase-specific histone H1 kinase (H1K) has been described in a wide variety of eukaryotic cell types undergoing the G2/M transition in the cell division cycle. We have used p13suc1-Sepharose affinity chromatography to purify H1K to near homogeneity from matured starfish oocytes. A yield of 67% was obtained. Active H1K behaves as a 90- to 100-kD protein and appears to be constituted of equimolar amounts of cyclin and p34cdc2. The p34cdc2 subunit becomes tyrosine-dephosphorylated as the H1K is activated during entry of the oocytes into M phase, whereas the cyclin subunit is reciprocally phosphorylated. Acid phosphatase treatment of inactive p34cdc2/cyclin complex induces p34cdc2 dephosphorylation and three- to eightfold stimulation of the enzyme activity. These results suggest that active M-phase-specific H1K is constituted of both dephosphorylated p34cdc2 and phosphorylated cyclin.
Comparison of Partial and Radical Laparascopic Nephrectomy: Long-Term Outcomes for Clinical T1b Renal Cell Carcinoma. (2018)

LPN is an effective treatment option in appropriately selected patients with cT1b RCC. It provides 5-year, 10-year overall survival and cancer specific survival comparable to those of LRN as well as better preservation of renal function than LRN. Overall survival and cancer specific survival are associated with nonmodifiable factors but not by the choice of operative technique.