gebhart/patrepeval huggingface dataset:
Automatic delineation algorithm for site-specific management zones based on satellite remote sensing data (2017)

In light of the increasing demand for food production, climate change challenges for agriculture, and economic pressure, precision farming is an ever-growing market. The development and distribution of remote sensing applications is also growing. The availability of extensive spatial and temporal data—enhanced by satellite remote sensing and open-source policies—provides an attractive opportunity to collect, analyze and use agricultural data at the farm scale and beyond. The division of individual fields into zones of differing yield potential (management zones (MZ)) is the basis of most offline and map-overlay precision farming applications. In the process of delineation, manual labor is often required for the acquisition of suitable images and additional information on crop type. The authors therefore developed an automatic segmentation algorithm using multi-spectral satellite data, which is able to map stable crop growing patterns, reflecting areas of relative yield expectations within a field. The algorithm, using RapidEye data, is a quick and probably low-cost opportunity to divide agricultural fields into MZ, especially when yield data is insufficient or non-existent. With the increasing availability of satellite images, this method can address numerous users in agriculture and lower the threshold of implementing precision farming practices by providing a preliminary spatial field assessment.
Studies on Organic Fluorine Compounds. VII. Trifluoromethylation of Aromatic Compounds (1970)

Trifluoromethyl iodide reacts with aryl halide in the presence of copper powder to give aryltrifluoromethane derivatives in a fairly good yield. This newly observed reaction is applicable to heterocyclic halides as well as benzene derivatives. Activities of halides are in the following order of readiness : iodide>bromide>chloride. Effects of solvents and natures of copper were examined.
Self-Organization of PEO-<i>g</i><i>raft</i>-Single-Walled Carbon Nanotubes in Solutions and Langmuir−Blodgett Films (2001)

Poly(ethylene oxide) (PEO), soluble in both water and many organic solvents, is grafted onto single-walled carbon nanotubes (SWNTs), and aggregation behaviors of the resulting PEO-graft-SWNT in solutions and in Langmuir−Blodgett (LB) films are investigated. SWNTs, cleaved by acid, are dispersed relatively well in DMF and water, but poorly in chloroform and THF. PEO-graft-SWNT was synthesized by treating acid-cut SWNTs with SOCl2, followed by a reaction with monoamine-terminated PEO in a DMF and water medium. Atomic force microscopy reveals that PEO and SWNT segments take expanded and extended conformations when freshly prepared PEO-graft-SWNTs are cast from water. When PEO-graft-SWNTs are dispersed in chloroform, each SWNT segment collapses into a globular aggregate. Aging the chloroform dispersion produces self-organized structures detectable by light scattering. Langmuir−Blodgett films made from this aged solution afford a surface-micelle structure in which the coagulated collapsed SWNT core is surrounded by extended PEO patches. Addition of DMF to this chloroform solution re-expands the SWNT segments, although not completely. These results demonstrate that the conformation of SWNTs can be controlled by solvent quality as if they are ordinary hydrocarbon-based block copolymers. Yet, the conformational change is not completely reversible, and coagulation, rather than entanglement, becomes the major event even at locally concentrated regions.
LCD/LED Digit recognition by iPhone (2011)

Home medical devices with LCD or LED screens are quite common. While they offer many conveniences, the data is usually not retained. In this thesis, an iPhone application will be introduced that recognizes the digits on LCD or LED screens. The user takes a picture of the desired LCD or LED, and the app will convert the image to text in seconds. The app also has an email feature that allows the user to send the picture and the text conveniently to a secure medical data logging database. A contour finding algorithm is illustrated in this application for image preprocessing. This algorithm is relatively faster and more efficient than typical image preprocessing techniques. The Tesseract optical character recognition engine will be implemented for recognition of digits. A two-step recognition process improves the accuracy of the recognition. In addition to the image processing techniques, cross-compiling, Objective-C coding and Cocoa TouchTM event handling are discussed in this application.
Sustainable Preparation of Supported Metal Nanoparticles and Their Applications in Catalysis (2009)

Metal nanoparticles have attracted much attention over the last decade owing to their unique properties as compared to their bulk metal equivalents, including a large surface-to-volume ratio and tunable shapes. To control the properties of nanoparticles with particular respect to shape, size and dispersity is imperative, as these will determine the activity in the desired application. Supported metal nanoparticles are widely employed in catalysis. Recent advances in controlling the shape and size of nanoparticles have opened the possibility to optimise the particle geometry for enhanced catalytic activity, providing the optimum size and surface properties for specific applications. This Review describes the state of the art with respect to the preparation and use of supported metal nanoparticles in catalysis. The main groups of such nanoparticles (noble and transition metal nanoparticles) are highlighted and future prospects are discussed.
Microfabricated polyester conical microwells for cell culture applications (2011)

Over the past few years there has been a great deal of interest in reducing experimental systems to a lab-on-a-chip scale. There has been particular interest in conducting high-throughput screening studies using microscale devices, for example in stem cell research. Microwells have emerged as the structure of choice for such tests. Most manufacturing approaches for microwell fabrication are based on photolithography, soft lithography, and etching. However, some of these approaches require extensive equipment, lengthy fabrication process, and modifications to the existing microwell patterns are costly. Here we show a convenient, fast, and low-cost method for fabricating microwells for cell culture applications by laser ablation of a polyester film coated with silicone glue. Microwell diameter was controlled by adjusting the laser power and speed, and the well depth by stacking several layers of film. By using this setup, a device containing hundreds of microwells can be fabricated in a few minutes to analyze cell behavior. Murine embryonic stem cells and human hepatoblastoma cells were seeded in polyester microwells of different sizes and showed that after 9 days in culture cell aggregates were formed without a noticeable deleterious effect of the polyester film and glue. These results show that the polyester microwell platform may be useful for cell culture applications. The ease of fabrication adds to the appeal of this device as minimal technological skill and equipment is required.
Crystal structure of cis‐biphenyl‐2,3‐dihydrodiol‐2,3‐dehydrogenase from a PCB degrader at 2.0 Å resolution (1998)

cis-Biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB) is involved in the aerobic biodegradation of polychlorinated biphenyls (PCBs). The crystal structure of the NAD+-enzyme complex was determined by molecular replacement and refined to an R-value of 17.9% at 2.0 A. As a member of the short-chain alcohol dehydrogenase/reductase (SDR) family, the overall protein fold and positioning of the catalytic triad in BphB are very similar to those observed in other SDR enzymes, although small differences occur in the cofactor binding site. Modeling studies indicate that the substrate is bound in a deep hydrophobic cleft close to the nicotinamide moiety of the NAD+ cofactor. These studies further suggest that Asn143 is a key determinant of substrate specificity. A two-step reaction mechanism is proposed for cis-dihydrodiol dehydrogenases.
THE DURAL TAIL SIGN IN THE DIAGNOSIS OF MENINGIOMAS (1998)

In humans the dural tail is a sign seen on contrast enhanced T1 weighted magnetic resonance images. This finding is considered specific for meningioma. The purpose of this study was to determine how often the dural tail occurs in cats and dogs and whether it is a specific sign for meningiomas in these species. MR examinations for eighteen dogs and four cats with proven diagnoses were reviewed. Diagnoses included ten meningiomas (seven dogs and three cats), three gliomas, two pituitary tumors, single examples of two other tumor types and five patients with mass lesions due to inflammatory disease. Contrast enhanced T1 weighted images were evaluated independently by three of the authors for the presence of a dural tail, without knowledge of the diagnoses. The results were compared to the diagnosis for each patient and the performance of individual reviewers compared. When their results were averaged, the reviewers reported the presence of a dural tail in 6 of 10 (60%) meningiomas, although detection varied between observers from 40% to 80%. Each reviewer had one false positive result, two reported a dural tail with a chromophobe adenocarcinoma and one with a toxoplasma meningoencephalitis. When a dural tail is seen an associated mass is most likely a meningioma. It is uncertain whether the dural tail represents neoplastic infiltration beyond the margins of the meningioma. This should be considered when planning treatment.
Diagnosis of pulmonary coccidioidal infections. (1951)

A wide variety of pulmonary lesions may be caused by coccidioidomycosis. Suspicion of coccidioidomycosis may be substantiated by careful clinical-epidemiological histories. The first laboratory procedure should be a coccidioidin skin test. If the reaction to the test is positive, serological tests are next. Also, if there is no reaction to coccidioidin, serological tests are still indicated if dissemination is suspected. The more severe the infection, the greater the probability of establishing a diagnosis serologically. In only three-fifths of patients with coccidioidal cavities can the diagnosis be fixed serologically. In such patients if differential skin tests are not conclusive, attempt should be made to recover the fungus. However, this is accompanied by great risk of laboratory infection. Eosinophilia and accelerated erythrocyte sedimentation are only circumstantial items of evidence, as is the appearance of the pulmonary roentgenogram.
Wave model solution to the ground/power plane noise problem (1995)

In this paper, we describe the development of a theoretical field-based or "wave" model which we are employing in an attempt to characterize the ground/power plane (e.g., the V/sub cc/ plane) structure of a printed wiring board (PWB) or multichip module (MCM). A brief development of the model is presented, followed by simulation results and insight into the noise phenomena. A test structure and electrical measurements are used to confirm the correctness and applicability of the model.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Using a semantic concordance for sense identification (1994)

This paper proposes benchmarks for systems of automatic sense identification. A textual corpus in which open-class words had been tagged both syntactically and semantically was used to explore three statistical strategies for sense identification: a guessing heuristic, a most-frequent heuristic, and a co-occurrence heuristic. When no information about sense-frequencies was available, the guessing heuristic using the numbers of alternative senses in WordNet was correct 45% of the time. When statistics for sense-frequencies were derived from a semantic concordance, the assumption that each word is used in its most frequently occurring sense was correct 69% of the time; when that figure was calculated for polysemous words alone, it dropped to 58%. And when a co-occurrence heuristic took advantage of prior occurrences of words together in the same sentences, little improvement was observed. The semantic concordance is still too small to estimate the potential limits of a co-occurrence heuristic.
Atorvastatin, an HMG‐COA reductase inhibitor and effective lipid‐regulating agent. Part III. Syntheses of [2H5]‐, [13C8], and [13C7,15N]atorvastatin and their application in metabolic and pharmacokinetic studies (1999)

Three stable-isotope-labeled forms of atorvastatin, [2H5], [13C8], and [13C7,15N], were synthesized. They were utilized primarily for metabolic mapping and pharmacokinetic studies of bioequivalence. Analytical assays were performed by using LC/MS/MS methodologies. Copyright © 1999 John Wiley & Sons, Ltd.
Differential acceleration of healing of surgical incisions in the rabbit gastrointestinal tract by platelet-derived growth factor and transforming growth factor, type beta. (1990)

Anastomotic dehiscence is a major cause of morbidity and mortality in gastrointestinal surgery. A unique model system of a gastric incision was developed to test the potential of polypeptide growth factors to enhance wound healing. Paired, deep partial-thickness incisions to but not including the gastric mucosa were made. A single topical application of transforming growth factor, type beta 1 (TGF-beta), platelet-derived growth factor, or control vehicle at the time of wounding was given. Wound breaking strength and detailed histologic analyses of wounds were evaluated as a function of time after wounding. TGF-beta (0.1 to 2.0 micrograms/wound) demonstrated a bimodal, dose-dependent acceleration of wound breaking strength 7 days after gastric wounding. An approximate 4-day acceleration of gastric wound breaking strength by TGF-beta (2 micrograms/wound) was seen at 7 and 11 days. Wounds treated with platelet-derived growth factor (10 micrograms/wound) displayed an increased cellular response but no enhancement of breaking strength at 7 and 11 days. These results demonstrate the ability of TGF-beta to accelerate gastrointestinal tissue repair by topical application and suggest significant potential for the use of growth factors in enhancing repair of surgical wounds of the gastrointestinal tract.
Protection and repair of the injured spinal cord: a review of completed, ongoing, and planned clinical trials for acute spinal cord injury (2008)

Over the past 2 decades, advances in understanding the pathophysiology of spinal cord injury (SCI) have stimulated the recent emergence of several therapeutic strategies that are being examined in Phase I/II clinical trials. Ten randomized controlled trials examining methylprednisolone sodium succinate, tirilizad mesylate, monosialotetrahexosylganglioside, thyrotropin releasing hormone, gacyclidine, naloxone, and nimodipine have been completed. Although the primary outcomes in these trials were laregely negative, a secondary analysis of the North American Spinal Cord Injury Study II demonstrated that when administered within 8 hours of injury, methylprednisolone sodium succinate was associated with modest clinical benefits, which need to be weighed against potential complications. Thyrotropin releasing hormone (Phase II trial) and monosialotetrahexosylganglioside (Phase II and III trials) also showed some promise, but we are unaware of plans for future trials with these agents. These studies have, however, yielded many insights into the conduct of clinical trials for SCI. Several current or planned clinical trials are exploring interventions such as early surgical decompression (Surgical Treatment of Acute Spinal Cord Injury Study) and electrical field stimulation, neuroprotective strategies such as riluzole and minocycline, the inactivation of myelin inhibition by blocking Nogo and Rho, and the transplantation of various cellular substrates into the injured cord. Unfortunately, some experimental and poorly characterized SCI therapies are being offered outside a formal investigational structure, which will yield findings of limited scientific value and risk harm to patients with SCI who are understandably desperate for any intervention that might improve their function. Taken together, recent advances suggest that optimism for patients and clinicians alike is justified, as there is real hope that several safe and effective therapies for SCI may become available over the next decade.
Sequence, structure, function, immunity: structural genomics of costimulation (2009)

Costimulatory receptors and ligands trigger the signaling pathways that are responsible for modulating the strength, course, and duration of an immune response. High-resolution structures have provided invaluable mechanistic insights by defining the chemical and physical features underlying costimulatory receptor:ligand specificity, affinity, oligomeric state, and valency. Furthermore, these structures revealed general architectural features that are important for the integration of these interactions and their associated signaling pathways into overall cellular physiology. Recent technological advances in structural biology promise unprecedented opportunities for furthering our understanding of the structural features and mechanisms that govern costimulation. In this review, we highlight unique insights that have been revealed by structures of costimulatory molecules from the immunoglobulin and tumor necrosis factor superfamilies and describe a vision for future structural and mechanistic analysis of costimulation. This vision includes simple strategies for the selection of candidate molecules for structure determination and highlights the critical role of structure in the design of mutant costimulatory molecules for the generation of in vivo structure-function correlations in a mammalian model system. This integrated 'atoms-to-animals' paradigm provides a comprehensive approach for defining atomic and molecular mechanisms.
Does Selection Mechanism for Temporary Employees in Public Sector Universities affect Right Selection? (2015)

Recruitment and selection of temporary and permanent employees have always remained one of a top priority ongoing function in public sector universities across the globe. Although temporary employees recruitment and selection facilitates effective screening of potential employees on permanent basis but the question is how does this take place in the public sector universities when it comes to the selection of permanent faculty members, this is main theme of this study to analyze the approaches of temporary selection and its impact on effectiveness of permanent selection. The data collection was made from the senior faculty members who had vast experience in the public sector universities. This study has identified that the temporary selections have influenced the right selection in two ways, the one these appointments were not based on merit and secondly these were preferred over permanent appointments as well. This is first such a study that has focused this phenomenon in non-English speaking countries, particularly in SAARC region of Asia.
The Lysosomal Trafficking Transmembrane Protein 106B Is Linked to Cell Death (2016)

A common genetic variation in the transmembrane protein 106B (TMEM106B) gene has been suggested to be a risk factor for frontotemporal lobar degeneration (FTLD) with inclusions of transactive response DNA-binding protein-43 (TDP-43) (FTLD-TDP), the most common pathological subtype in FTLD. Furthermore, previous studies have shown that TMEM106B levels are up-regulated in the brains of FTLD-TDP patients, although the significance of this finding remains unknown. In this study, we show that the overexpression of TMEM106B and its N-terminal fragments induces cell death, enhances oxidative stress-induced cytotoxicity, and causes the cleavage of TDP-43, which represents TDP-43 pathology, using cell-based models. TMEM106B-induced death is mediated by the caspase-dependent mitochondrial cell death pathways and possibly by the lysosomal cell death pathway. These findings suggest that the up-regulation of TMEM106B may increase the risk of FTLD by directly causing neurotoxicity and a pathological phenotype linked to FTLD-TDP.
Accurate face models from uncalibrated and ill-lit video sequences (2004)

We propose a face reconstruction technique that produces models that not only look good when texture mapped, but are also metrically accurate. Our method is designed to work with short uncalibrated video or movie sequences, even when the lighting is poor resulting in specularities and shadows that complicate the algorithm's task. Our approach relies on optimizing the shape parameters of a sophisticated PCA based model given pairwise image correspondences as input. All that is required is enough relative motion between camera and subject so that we can derive structure from motion. By matching the results against laser scanning data, we will show that its precision is excellent and can be predicted as a junction of the number and quality of the correspondences. This is important if one wishes to obtain the appropriate compromise between processing speed and quality of the results. Furthermore, our method is in fact not specific to faces and could equally be applied to any shape for which a shape model controlled with relatively small number of parameters exists.
Automatic Entity Recognition and Typing in Massive Text Corpora (2016)

In today's computerized and information-based society, we are soaked with vast amounts of natural language text data, ranging from news articles, product reviews, advertisements, to a wide range of user-generated content from social media. To turn such massive unstructured text data into actionable knowledge, one of the grand challenges is to gain an understanding of entities and the relationships between them. In this tutorial, we introduce data-driven methods to recognize typed entities of interest in different kinds of text corpora (especially in massive, domain-specific text corpora). These methods can automatically identify token spans as entity mentions in text and label their types (e.g., people, product, food) in a scalable way. We demonstrate on real datasets including news articles and yelp reviews how these typed entities aid in knowledge discovery and management.
Solvate Prediction for Pharmaceutical Organic Molecules with Machine Learning (2019)

Methods to predict crystallization behavior for active pharmaceutical ingredients (APIs) can serve as an important guide in small molecule pharmaceutical development. Here, we describe solvate formation propensity prediction for pharmaceutical molecules via a machine learning approach. Random forests (RF) and support vector machine (SVM) algorithms were trained and tested with data sets extracted from Cambridge Structural Database (CSD). The machine learning models, requiring only 2D structures as input, were able to predict solvate formation propensity for organic molecules with up to 86% success rate. Performance of the models was demonstrated with a collection of 20 pharmaceutical molecules.
특성 길이를 이용한 평직 복합재 볼트 체결부의 강도 예측 (2003)

A study on predicting the joint strength of mechanically fastened woven glass/epoxy composite has been performed. An experimental and numerical study were carried out to determine the characteristic length and joint strength of composite joint. The characteristic lengths for tension and compression were determined from the tensile and compressive test with a hole respectively. The characteristic lengths were evaluated by applying the point stress failure criterion to a specimen containing a hole at the center subjected to tensile loading and a specimen containing a half circular notch at the center subjected to compressive load. The joint strength was evaluated by the Tsai-Wu and Yamada-Sun failure criterion on the characteristic curve. The predicted results of the joint strength were compared with experimental results.