gebhart/patrepeval huggingface dataset:
The Nature of the Stable Blood Clot Procoagulant Activities (2008)

The function of tissue factor (Tf)-initiated coagulation is hemorrhage control through the formation and maintenance of an impermeable platelet-fibrin barrier. The catalytic processes involved in the clot maintenance function are not well defined, although the rebleeding problems characteristic of individuals with hemophilias A and B suggest a link between specific defects in the Tf-initiated process and defects in the maintenance function. We have previously demonstrated, using a methodology of "flow replacement" (or resupply) of ongoing Tf-initiated reactions with fresh reactants, that procoagulant complexes are produced during Tf-initiated coagulation, which are capable of reinitiating coagulation without input from extrinsic factor Xase activity (Orfeo, T., Butenas, S., Brummel-Ziedins, K. E., and Mann, K. G. (2005) J. Biol. Chem. 280, 42887-42896). Here we used Tf-initiated reactions in normal and hemophilia blood or in their corresponding proteome mixtures as sources of procoagulant end products and then varied the resupplying material to determine the identity of the catalysts that drive the new cycle of thrombin formation. The central findings are as follows: 1) the prothrombinase complex (fVa-fXa-Ca(2+)-membrane) accumulated during the episode of Tf-initiated coagulation is the primary catalyst responsible for the observed pattern of prothrombin activation after resupply; 2) impairments in intrinsic factor Xase function, i.e. hemophilias A and B, result in an impaired capacity to mount a resupply response; and 3) in normal hemostasis the intrinsic factor Xase function contributes to the durability of the resupply response.
Low-loss contact pad with turned impedance for operation at millimeter wave frequencies (2005)

In this paper an on-chip pad structure with minimized losses and matched impedance is presented. The pads use a metal ground-shield thereunder to minimize the influence from a lossy silicon substrate. A shunt transmission line stub is used to resonate the pad capacitance, thereby providing a matched impedance into a 50 /spl Omega/ on-chip transmission line. A second-tier calibration technique was used to extract their 2-port S-parameter characteristic. The measured performance is compared with simulations of standard pad structures up to 65 GHz.
Introduction: Africa and the World of Regionalism: Old and New (1997)

Regional integration is not new. It has been a continuing part of the post-World War II trade landscape. Recently, however, interest in regionalism has revived in both developed and developing countries. Existing arrangements have been, or are being, extended in their coverage; old arrangements are being revived; and new regional groupings are being formed. The three distinctive features of this trend are: the ‘conversion’ of the United States to the regional approach; the emergence of regional arrangements among industrial and developing countries; and an apparent move away from inward-oriented towards more outward-oriented arrangements among developing countries, particularly in the Western Hemisphere. In developing countries, these developments are being accompanied in many cases by unilateral trade liberalization.
Emotion recognition from speech using convolutional neural network with recurrent neural network architecture (2017)

Recognition of emotion is always a difficult problem, particularly if the recognition of emotion is done by using speech signal. Many significant research works have been done on emotion recognition using speech signal. The primary challenges of emotion recognition are choosing the emotion recognition corpora (speech database), identification of different features related to speech and an appropriate choice of a classification model. In this article we use 13 MFCC (Mel Frequency Cepstral Coefficient) with 13 velocity and 13 acceleration component as features and a CNN (Convolution Neural Network) and LSTM (Long Short Term Memory) based approach for classification. We chose Berlin Emotional Speech dataset (EmoDB) for classification purpose. We have approximately 80 percent of accuracy on test data.
Pre-screening of single contingencies causing network topology changes (1991)

A multilevel contingency screening method is introduced to process large sets of candidate power system contingencies. The idea is to apply a series of increasingly more accurate and time-consuming algorithms so that each higher screening level processes a reduced set of candidates. A practical implementation of the method uses a fast prescreening step whose algorithm is based upon the local network solution concept. The method is designed to process contingencies whose effects can be localized, e.g. branch outages and bus section faults. The accuracy of the new algorithm is controlled via an automatically calculated small network adequacy ratio while its reliability is enhanced by the use of different contingency severity measures.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Synthesis and some pharmacological properties of oxytocin analogues having L-thiazolidine-4-carboxylic acid in position 7 (1976)

[7-Thiazolidine-4-carboxylic acid)]oxytocin and [1-beta-mercaptopropionic acid,7-(thiazolidine-4-carboxylic acid)]oxytocin have been synthesized by a solid-phase method. Alpha-N-tert-Butoxycarbonyl- and S-ethylcarbamoyl-protecting groups were employed. The dipeptide Boc-Cys(Ec)-thiazolidine-4-carboxylic acid as well as individual residues was coupled to a H-Gly-dehydroalanine-resin with dicyclohexylcarbodiimide in the presence of 1-hydroxybenzotriazole. The appropriate protected polypeptide intermediates were cleaved from the resin by acidolysis, deprotected in NH3, and oxidized to the cyclic disulfide analogues with ICH2CH2I. Purification was effected by partition chromatography and gel filtration. Relative to oxytocin and [1-beta-mercaptopropionic acid]oxytocin, these analogues exhibit greatly enhanced oxytocic and avian vasodepressor potencies and unchanged rat pressor potencies.
Saccharomyces cerevisiae recombinant Pfs25 adsorbed to alum elicits antibodies that block transmission of Plasmodium falciparum (1994)

Antibodies to Pfs25, a cysteine-rich 25-kDa protein present on the surface of Plasmodium falciparum zygotes, can completely block the transmission of malaria parasites when mixed with infectious blood and fed to mosquitoes through a membrane feeding apparatus. Recently, a polypeptide analog, Pfs25-B, secreted from recombinant Saccharomyces cerevisiae was found to react with conformation-dependent, transmission-blocking monoclonal antibodies and to elicit transmission-blocking antibodies in experimental animals when emulsified in either Freund's or muramyl tripeptide adjuvant. In this study, Pfs25-B adsorbed to alum induced transmission-blocking antibodies in both rodents and primates. Bacterially produced Pfs25, however, did not elicit complete transmission-blocking antibodies in rodents. Furthermore, unlike monoclonal antibodies to Pfs25, which block transmission only after ookinete development, antisera to Pfs25-B adsorbed to alum appeared to block the in vivo development of zygotes to ookinetes as well.
MIMO PLC: Theory, measurements and system setup (2011)

Inhome Power Line Communications (PLC) enables new and highly convenient networking functions without any additional wires to mains-powered devices. Multiple Input Multiple Output (MIMO) methods significantly improve the coverage of guaranteed data throughputs in private homes. This paper gives an overview on MIMO PLC. The results from the channel measurements motivate to implement a MIMO PLC feasibility study in hardware. The system demonstrates HD video streaming over a 2×4 MIMO channel using Beamforming. A MIMO artificial mains network allows testing of the system in the laboratory.
Various methods for determining urinary choriogonadotropin evaluated for the early diagnosis of ectopic pregnancy. (1986)

We evaluated the accuracy, sensitivity, specificity, and performance characteristics of seven methods for determining urinary choriogonadotropin in the early diagnosis of ectopic pregnancy in 46 patients with gynecological emergencies. The kits examined included immunoenzymometric assays (Tandem Icon hCG, Model Plus, Diapreg-25, Pregnastick, Nimbus) and reverse hemagglutination inhibition assays (NeoPregnosticon 75 Duoclon, Pregtest). We found immunoenzymometric assays to be the most sensitive procedures (lowest detection limits) for qualitatively detecting hCG secreted by ectopic pregnancy. We concluded that the Tandem Icon best meets our criteria and we advocate its use in the emergency room or ward as the first-line investigation of ectopic pregnancy. In addition, the use of Diapreg-25 has many theoretical advantages as an extremely sensitive index of choriogonadotropin status because of its ability to detect very low concentrations of beta subunit.
Exploiting graphics hardware for haptic authoring. (2006)

Real-time, plausible visual and haptic feedback of deformable objects without shape artifacts is important in surgical simulation environments to avoid distracting the user. We propose to leverage highly parallel stream processing, available on the newest generation graphics cards, to increase the level of both visual and haptic fidelity. We implemented this as part of the University of Florida's haptic surgical authoring kit.
Dial One for Scam: A Large-Scale Analysis of Technical Support Scams (2017)

Author(s): Najmeh Miramirkhani, Oleksii Starov, Nick Nikiforakis Download: Paper (PDF) Date: 27 Feb 2017 Document Type: Reports Additional Documents: Slides Video Associated Event: NDSS Symposium 2017 Abstract: In technical support scams, cybercriminals attempt to convince users that their machines are infected with malware and are in need of their technical support. In this process, the victims are asked … Continued
<i>The First Vietnam Crisis: Chinese Communist Strategy and United States Involvement, 1953-1954</i>, by Melvin Gurtov (1969)

"The First Vietnam Crisis: Chinese Communist Strategy and United States Involvement, 1953-1954, by Melvin Gurtov." Canadian Journal of History, 4(1), pp. 130–131
Radioimmunoassay for neurotensin, a hypothalamic peptide. (1976)

A highly sensitive and specific radioimmunoassay for neurotensin has been developed which utilizes 125I-labeled neurotensin and rabbit antisera raised toward synthetic neurotensin which has been coupled specifically through its lysine side chain to several proteins. The three antisera described have different specificities but are directed primarily towards the COOH-terminal region of neurotensin which is the biologically active portion of the molecule. Two of the antisera, poly(Glu60, Lys40) (from animal no. 4) and keyhole limpet hemocyanin (from animal no. 8), cross-react fully with COOH-terminal partial sequences of neurotensin while antiserum poly(Glu60, Lys40) (from animal no. 6) requires the entire molecule for full recognition. The assay can detect less than 3 fmol of neurotensin and the dose-response curves for synthetic and native neurotensin are superimposable, irrespective of the antiserum employed. Using these assay systems, the immunoactivity in acid/acetone extracts of 45 kg of bovine hypothalami was purified to homogeneity and shown to be attributable to intact neurotensin and not to fragments of neurotensin nor to related molecules. Radioimmunoassayable neurotensin (R-NT) obtained from bovine, rat, guinea pig, and rabbit hypothalami also gave dose-response curves which paralleled that of neurotensin and the neurotensin equivalents per g of wet tissue were in the range 45 to 70 pmol/g. Measurements with the three antisera were in agreement, especially after the extracts were chromatographed on Sephadex G-25; R-NT in these hypothalamic extracts has also been shown to be destroyed by treatment with various enzymes known to cleave neurotensin.
3,000-fps 3-D shape measurement using a high-speed camera-projector system (2007)

This paper proposes a high frame rate 3-D shape measurement system based on structured light projection using temporally-coded binary patterns. This system consists of a DMD (digital micromirror device) projector and a high-speed camera, both of which operate at over 6,000 fps. Introducing an image processing algorithm of detecting and tracking the projected light patterns enables frame-by-frame 3-D image measurement. Experimental results show that the proposed algorithms worked effectively, and the system achieved 3-D imaging at 3,350 fps.
Preparation of syndiotacticity‐rich high molecular weight poly(vinyl alcohol)/iodine polarizing film with high water resistance (2009)

Abstract To enhance durability of poly(vinyl alcohol) (PVA)/iodine polarizing film under humid and warm atmospheres and to identify the effects of syndiotacticity on the polarizing efficiency (PE) and durability of PVA/iodine complex film, we prepared three high molecular weight (PVA)s with similar number‐average degree of polymerization ( P n ) of 4000 and with different syndiotactic diad (s‐diad) contents of 53, 56, and 59%, respectively. It was found that syndiotacticity of PVA had a significant influence on the durability of PVA/iodine complex film in warm and humidity conditions (relative humidity of 80% and temperature of 50°C). That is, both desorption of iodine in PVA/iodine film and transmittance of film decreased with increasing syndiotacticity of PVA. In the case of PE, the values of over 99% were obtained at each optimum conditions. The change of PE (durability) of PVA/iodine complex films having P n of 4000 and s‐diad contents of 56 and 59%, respectively, in warm and humidity conditions was almost zero, whereas those of PVA/iodine film with s‐diad content of 53% and with ( P n )s of 1700 and 4000 were about 60% and 50%, respectively, under same conditions. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Compact system description for systems comprising a tilted plane parallel plate (2007)

A paraxial model describing the astigmatism generated by a plane-parallel plate is derived. This model fits the framework of the 4x4 matrix formalism that Arsenault used to describe cylindrical lenses. The framework including this new model is used to build a compact system description of a plane-parallel plate combined with a cylindrical lens, from which several imaging properties are derived. Calculation results are compared with ray-trace simulation results and measurements. Both the ray-trace and the experimental results are in excellent agreement with the calculated results.
Extracellular matrix dermatopontin modulates prostate cell growth in vivo (2006)

Dermatopontin is a tyrosine-rich acidic extracellular matrix protein of 22 kDa with possible functions in cell-matrix interactions and matrix assembly. We have previously isolated mRNAs expressed in hormone-refractory, but not in hormone-sensitive, mouse mammary cancer by comparing the mRNAs expressed in either tumor. A partial mRNA sequence isolated was later proven to be a part of mouse dermatopontin mRNA sequence. Transfectants of mouse dermatopontin cDNA into PC-3 human prostate cancer cells enhanced tumor growth when those were implanted subcutaneously in nude mice compared with the controls. Those transfectants showed a prominent stroma compared with the controls. Localization of the targets of a fusion protein of mouse dermatopontin and alkaline phosphatase was in the stroma of the PC-3 tumor tissues, but not in the tumor cells themselves. Additionally, we have established mouse dermatopontin transgenic mice under the control of the rat probasin promoter. The prostatic dorsal lobes of dermatopontin transgenic mouse showed prostate intra-epithelial neoplasia at the age of 11 months, but the control littermates did not. Epithelium of other prostatic lobes was not markedly different from that of the controls. In conclusion, dermatopontin may be involved in the pathogenesis and growth of the prostate cancer.
Stress Relaxation in Porous GaN Prepared by UV Assisted Electrochemical Etching (2018)

This study describes the stress relaxation in porous GaN grown on Al2O3 substrates. The results indicate that the stress relaxation has taken place in the samples which increases by increasing the etching current. As compared to the as-grown GaN films, porous GaN exhibits substantial photoluminescence (PL) intensity enhancement with red-shifted band-edge peaks associated with the relaxation of the compressive stress. The red shifted phonon energy peak (E2) in the Raman spectra of the porous GaN films confirms further such a stress relaxation. Scanning electron microscopy (SEM) demonstrates that, the current density has significant effect on the size and shape of the pores.
Preparing Communities for Flooding: Some Recent Lessons and Some Ways Forward (1991)

Severe floods in New South Wales during 1990 taught many lessons about preparing the state and community adequately to face the flooding. Communities, which have developed a range of appropriate preparatory measures are ready for most disasters and will survive serious flooding with less damage and trauma imposed on them.
A Deep Reinforcement Learning Based Multi-Step Coarse to Fine Question Answering (MSCQA) System (2019)

In this paper, we present a multi-step coarse to fine question answering (MSCQA) system which can efficiently processes documents with different lengths by choosing appropriate actions. The system is designed using an actor-critic based deep reinforcement learning model to achieve multistep question answering. Compared to previous QA models targeting on datasets mainly containing either short or long documents, our multi-step coarse to fine model takes the merits from multiple system modules, which can handle both short and long documents. The system hence obtains a much better accuracy and faster trainings speed compared to the current state-of-the-art models. We test our model on four QA datasets, WIKEREADING, WIKIREADING LONG, CNN and SQuAD, and demonstrate 1.3%-1.7% accuracy improvements with 1.5x-3.4x training speed-ups in comparison to the baselines using state-of-the-art models.
UPS systems for remote or temporary telecom locations (2002)

Many requirements for UPS systems for use in remote telecommunication locations are quite clear: they must be compact, easily transportable, flexible in use and able to operate with minimum maintenance. Severe climatic and EMC requirements, both on emission and immunity, also are common. These requirements also apply to temporary UPS systems. Less clear are the special requirements that result from the generally long feeders and their associated high impedance. Any fluctuation in feeder current like surges, reactive power variations and harmonics, give larger than normal disturbances at the end of the feeder cable, and produce unacceptable dips or voltage distortion to AC loads in the telecommunication station, including to the UPS system itself. Many of these problems become significant at higher power ratings, above a few hundred kVA, when solutions like filters and batteries are less effective or difficult to install at remote or temporary sites. An alternative in the form of a containerised, diesel-powered UPS is presented.
New Respiratory Viral Infections (2008)

1 Severe acute respiratory syndrome(SARS)is caused by a previously unrecognized coronavirus (CoV)which jumped species and became adapted to be transmissible between humans in2002 . Enormous scientific knowledge about this SARS-CoV has been accumulated and aspects of its pathogenesis defined .However it is still unclear why some members of the same family or housing estate with SARS outbreak were more susceptible to SARS than others.Similarly,why children have a lower incidence of SARS with milder clinical course as compared to adults remains unknown.
Doxorubicin and octreotide induce a 40 kDa breakdown product of p53 in human hepatoma and tumoral colon cell lines (2002)

The chemotherapeutic drug doxorubicin and the anti-proliferative long-acting somatostatin analogue octreotide, both used in cancer treatment, have been shown to increase the expression of the p53 tumour suppressor protein. In the present study, we demonstrate by Western-blot analysis that, in addition to the p53 protein, these molecules were able to induce the expression of a shorter protein with an apparent molecular mass of 40 kDa (p40), recognized by antibodies raised against the N-terminus of p53. This induction was present in tumoral and non-tumoral cells and did not depend on the status of the endogenous p53 protein. The p40 protein was significantly induced after 3 h of cell treatment with doxorubicin or octreotide, remained stable until 24 h and was located in the nuclear extract. Using reverse primers corresponding to each exon of the p53 gene, only one transcript was amplified by reverse transcriptase-PCR. This suggested that p40 was issued from a post-translational modification and not from an alternative splicing. This protein was not recognized by the PAb421 antibody, suggesting that it was issued from a cleavage of the p53 C-terminal region (p40deltaC). Furthermore, this cleavage was not dependent on caspase activity. In conclusion, these results support the hypothesis that this post-translational modification plays a significant role in the regulation of multiple p53 signalling pathways. These results also suggest that octreotide, a molecule with different signalling pathways, was able as doxorubicin to generate a p53 breakdown product.
Transparent fault-tolerance in parallel Orca programs (1992)

With the advent of large-scale parallel computing systems, making parallel programs fault-tolerant becomes an important problem, because the probability of a failure increases with the number of processors.In this paper, we describe a very simple scheme for rendering a class of parallel Orca programs fault-tolerant.Also, we discuss our experience with implementing this scheme on Amoeba.Our approach works for parallel applications that are not interactive.The approach is based on making a globally consistent checkpoint from time to time and rolling back to the last checkpoint when a processor fails.Making a consistent global checkpoint is easy in Orca, because its implementation is based on reliable broadcast.The advantages of our approach are its simplicity, ease of implementation, low overhead, and transparency to the Orca programmer.
Modulation of collagen synthesis and its gene expression in human skin fibroblasts by tocotrienol-rich fraction (2011)

Tocotrienol-rich fraction protects against H(2)O(2)-induced oxidative stress in human skin fibroblast culture by modulating the expression of COL I and COL III genes with concomitant increase in the rate of total collagen synthesis. These findings may indicate TRF protection against oxidative stress-induced skin aging.
Hydroxyproline Heterooligosaccharides in <i>Chlamydomonas</i> (1972)

Most of the hydroxyproline in Chlamydomonas reinhardtii is glycosidically linked to oligosaccharides and a monosaccharide that are different from the arabinosides found in hydroxyproline-containing plant cell walls previously examined. Of particular interest is the presence of hydroxyproline-O-galactose. These differences may be common to the volvocalean green algae and may be related to lower tensile strength of the cell walls of this group of plants.