gebhart/patrepeval huggingface dataset:
Comparison between Tail Skin Blood Flow Measurements by Ultrasonic Doppler Flowmetry and Plethysmography during Heating in Anesthetized Rats. (1999)

Tail skin blood flow (TBFu) was directly measured in anesthetized and passively heated rats by ultrasonic Doppler flowmetry during heating, and the values were compared to those (TBFp) simultaneously measured by venous-occlusion plethysmography. TBFp was estimated from the values per unit tissue multiplied by the tail volume, the shape of which was assumed to be a cone. TBFp was highly correlated with TBFu, with a regression equation of TBFp = 0.7TBFu+0.1 (r2 = 0. 94, p<0.001). Although TBFp was slightly lower than TBFu, the equation is useful to estimate the absolute values of tail skin blood flow from the values of plethysmography in awake rats.
Time-gated Full-field Optical Coherence Tomography and Application to Rat Brain (2006)

We demonstrated time-gated full-field OCT with in vitro and in situ brain. Images for in vitro were measured with area of 170x170μm, depth of 430 μm and exposure time of 3.6 ms.
Murine Models of Inflammatory Bowel Disease (IBD) (2013)

Animal models of human disease are a critical tool in both basic research and drug development. The results of preclinical efficacy studies often inform progression of therapeutic candidates through the drug development pipeline; however, the extent to which results in inflammatory bowel disease (IBD) models predict human drug response is an ongoing concern. This review discusses how murine models are currently being used in IBD research. We focus on the considerations and caveats for commonly used models in preclinical efficacy studies and discuss the value of models that utilize specific pathogenic pathways of interest rather than model all aspects of human disease.
Cerebral circulation in the elderly. (1993)

A great deal of knowledge has been accumulated in recent years, concerning the aging human brain in health and disease, with the advent of newer methods of measuring cerebral blood flow (CBF) and metabolism. It is well documented that even in normal aging, the functional metabolism of the brain and its blood supply inevitably decline. This accounts for the widespread clinical observations that the young tolerate disorders of the brain better than do the elderly. It also accounts for difficulties in correctly diagnosing and treating cognitive disorders among the elderly. Neuronal and vascular reserves become progressively depleted during normal aging, so that one or more different disease processes may contribute to cognitive declines. Computed tomography (CT) densitometry, coupled with xenon-enhanced CT CBF measurements, provide a noninvasive method for separating the changes within cerebral cortex, subcortex, and white matter that occur in normal aging from those due to pathological abnormalities.
25 Gbps direct modulation and 10 km data transmission with 1310 nm waveband wafer fused VCSELs (2016)

Direct modulation at >25 Gbps is achieved with 1310 nm wavelength wafer fused VCSELs by adjusting the strain in the quantum well active region and the cavity photon lifetime. 25 + Gbps large signal modulation with 10<sup>-12</sup> BER at 1310 nm across 10 km of standard single mode fiber is demonstrated.
Load Carrying Capacity of Spur Gears : A New Gear-Load Testing Machine and Running-in and Failure of Gears Having a Lengthwise Tooth Error (1973)

A new type of power-circulating, four square gear-load-testing machine in which the test gears can be loaded while they are rotating is introduced. This machine, having a capacity of 200 horse power at 1800 rpm, was designed by the authors and made in their laboratory. The results obtained were as follows : (1) The testing machine was simple in mechanism and gave no trouble during lengthy running tests of over 2×107 rotations because it was designed such that the gear load could be applied mechanically using a pair of circular-arc-tooth-trace cylindrical gears (having advantageous properties such as self-centering action, due to which the load applying mechanism became very simple), oil lubricated helical and spur splines, etc.(2) Test gears could be operated beyond 5×106 rotations producing only a very small number of pits (pitting area ratio less than 0.1%) at a Hertzian stress of 0.42 HB which was greater than the Hertzian stress 0.4 HB corresponding to the tangential load which produced the maximum reversed shear stress at the subsurface nearly equal to the endurance limit in reversed twisting (where, HB is Brinell hardness before running).(3) It seems that past discussions made on the mechanism of pitting occurring on gear tooth surfaces must be re-examined fully using the data obtained by the authors.(4) It was clarified that the equations given by D.W. Dudley for calculating the allowable tangential load on spur gears with tooth-end contact were very insufficient in practice and that new equations based on the authors' experiments gave good results because the effects of running-in were taken into account.
The attack of ozone on stretched rubber vulcanizates. III. Action of antiozonants (1962)

Abstract The character and extent of protection by certain additives (antiozonants) have been investigated for a number of vulcanized rubbers over a wide range of ozone concentrations. Two distinct modes of action are found: a reduction in the rate of crack growth and an increase in the critical energy necessary for attack to occur. Neither seems explicable on a simple hypothesis of scavenging. Several materials which act in the first manner have been examined. They were found to be similar in effect, reducing the growth rate to about one fifth of its original value when a sufficient amount of the additive was present. The mechanism is obscure. Certain additives, notably N , N ′‐dioctyl‐ p ‐phenylenediamine, also cause a striking and important increase in the critical energy condition. The circumstances under which this occurs have been studied, and a tentative hypothesis for the mode of action is advanced.
Analysis and Design of an Offshore Wind Farm Using a MV DC Grid (2010)

This paper outlines the design of an offshore wind farm using a dc offshore grid based on resonant dc-dc converters. Multiphase resonant dc-dc converters are studied to step up the dc voltage from individual wind generators to a Medium Voltage (MV) dc bus, and from the MV bus to an HVDC line that will connect the wind farm to shore. Compared to an equivalent ac grid-based wind farm, a dc grid-based wind farm has slightly higher losses, but the weight of the magnetic components and cables is substantially lower. The analysis of operating permanent-magnet synchronous generators at variable and constant dc voltages shows that a fixed dc voltage has marginally higher efficiency than a variable dc voltage. However, using a variable dc voltage gives lower harmonics at the generator facing the voltage-source converter and the dc-dc step-up converter. An aggregated model of multiple parallel connected wind generators is developed and shown to accurately approximate a detailed PSCAD model during varying wind conditions and transients.
Protein 'smart' micro/nano-biooptics via femtosecond laser direct writing (2013)

Protein-hydrogel-based free-form three-dimensional (3D) micro/nano-elements with ‘‘smart’’ stimuli-responsiveness fabricated via femtosecond laser direct writing (FsLDW) have attracted increasing efforts for their wide utilities in many fields, such as bio-micro/nano-machine <sup>[1]</sup>, biophotonics <sup>[2, 3]</sup>, etc. All processes of this protein-FsLDW are carried out in proteins’ aqueous solutions, as a result of which the approach is noncontact, maskless and biocompatible. So, we applied the promising FsLDW approach, which, in the construction of protein-based 3D optical microdevices, for example, microlenses. In order to meet the requirements of optical applications, FsLDW system and processing parameters were carefully optimized to achieve high-quality surface and 3D morphology. The photo-crosslinked protein microhydrogels showed a rapid and reversible swell-to-shrink behavior once stimulated by chemical signals, by which the protein microdevices can be dynamically tuned. Because of using protein molecules as “building blocks”, protein-based microelements were demonstrated of good biocompatibility. Based on the valuable and unique merits, protein-based optical micro/nano-elements have great potential for micro/nano-bio-optics, bionics, and novel biomedical applications, etc.
Autonomous agents for online diagnosis of a safety-critical system based on probabilistic causal reasoning (2003)

The goal of decentralization in failure detection, identification, and recovery of high-assurance systems is to focus diagnosis on safety-critical components. The goal of probabilistic causal reasoning in diagnosis is to improve performance of fault isolation, However, this reasoning method is dependent on prior reliability knowledge. Our approach aims at focusing the overall diagnostic cycle in two independent ways: first, autonomous agents diagnose high-consequence appliances of a modular manufacturing system and second prior reliability data needed is derived from a quality assurance program. Therefore we present a hybrid technique in combining quality assurance data, failure mode and effects analysis and probabilistic causal reasoning. We develop a dynamic Bayesian network which, given evidence from sensor observations, is able to learn and reason over time. We successfully apply autonomous diagnosis agents in concert with reliability assessment to improve online diagnosis of a pneumatic-mechanical device.
A Design Space to Support the Development of Windshield Applications for the Car (2016)

In this paper we present a design space for interactive windshield displays in vehicles and discuss how this design space can support designers in creating windshield applications for drivers, passengers, and pedestrians. Our work is motivated by numerous examples in other HCI-related areas where seminal design space papers served as a valuable basis to evolve the respective field -- most notably mobile devices, automotive user interfaces, and interactive public displays. The presented design space is based on a comprehensive literature review. Furthermore we present a classification of 211 windshield applications, derived from a survey of research projects and commercial products as well as from focus groups. We showcase the utility of our work for designers of windshield applications through two scenarios. Overall, our design space can help building applications for diverse use cases. This includes apps inside and outside the car as well as applications for specific areas (fire fighters, police, ambulance).
Equipment for on-site testing of HV insulation (1999)

On-site testing has often been requested by the utilities following installation of new HV cables and also to check the condition of HV power transformers suspected of a damaged insulation. Specialized equipment for on-site tests has to withstand off-road transportation, to pass under road-bridges, be equipped with its own power source, and what is most difficult, to make measurements at HV substations which are notorious for intense electromagnetic interference. At present a HV resonant test set-up with the partial discharge (PD) measuring instrument and the C-tgδ bridge with built-in test voltage source are the most frequently used mobile test equipment. This paper presents a mobile HV resonant test set-up for installed cable testing and measuring instruments designed for on-site transformer insulation testing. (4 pages)
New Approach to Multi-material Processing in Selective Laser Melting (2016)

New method and SLM machine for 3D multi-material parts production has been elaborated. SLM machine concept and concept of the build platform cleaning system is presented and discussed. New optical monitoring system has been elaborate. Results of test applying for powder feeding to test object are presented. Special metodology of the multi-material object sintering is proposed for better accuracy of 3D object production having regards to shrinkage and dissolution.
Glucocorticoids increase the responsiveness of cells in culture to prostaglandin E <sub>1</sub> (1977)

The influence of steroid hormones on the response of human astrocytoma cells (1321N1) to prostaglandin E(1) (PGE(1)) has been investigated. Responsiveness to PGE(1) was determined by measuring the conversion of [(3)H]ATP to cyclic [(3)H]AMP in cells prelabeled with [(3)H]adenine. After incubation of the cells with dexamethasone, a marked increase in both the maximal effect (2- to 3-fold) and the potency (5-fold) of PGE(1) was observed. The effect was specific for the action of PGE(1) in that no change in the response of the cells to isoproterenol was observed. The EC(50) for dexamethasone was 0.001 muM and the effect was dependent on the presence of serum. The effect of dexamethasone was first observed after a 30- to 60-min lag and was maximal by 6-8 hr. Preconfluent cultures (3 days after seeding) exhibited optimal responsiveness to glucocorticoids. Both hydrocortisone and corticosterone mimicked the effect of dexamethasone but both were less potent. The action of dexamethasone was blocked by progesterone, testosterone, and 17alpha-methyltestosterone. Cycloheximide, at a concentration (1.0 mug/ml) that blocked protein synthesis (>90%) in 1321N1 cells, totally prevented the effect of dexamethasone on the response of the cells to PGE(1). Upon removal of dexamethasone from cells treated for 16 hr, responsiveness to PGE(1) returned to control levels with a half-time of 4 hr. Dexamethasone also was found to increase the response to PGE(1) of a Rous sarcoma virus-transformed human astrocytoma cell line and the WI-38 human fibroblast line. The most obvious interpretation of our findings is that glucocorticoids induce the synthesis of a protein that selectively modifies the sensitivity of adenylate cyclase to PGE(1).
Clinical trial: the effects of a trans‐galactooligosaccharide prebiotic on faecal microbiota and symptoms in irritable bowel syndrome (2008)

The galactooligosaccharide acted as a prebiotic in specifically stimulating gut bifidobacteria in IBS patients and is effective in alleviating symptoms. These findings suggest that the prebiotic has potential as a therapeutic agent in IBS.
Semantically indexed hypermedia (1999)

article Semantically indexed hypermedia: linking information disciplines Share on Authors: Douglas Tudhope University of Glamorgan, Hypermedia Research Unit School of Computing, Pontypridd, CF37 1DL, Wales, UK University of Glamorgan, Hypermedia Research Unit School of Computing, Pontypridd, CF37 1DL, Wales, UKView Profile , Daniel Cunliffe University of Glamorgan, Hypermedia Research Unit School of Computing, Pontypridd, CF37 1DL, Wales, UK University of Glamorgan, Hypermedia Research Unit School of Computing, Pontypridd, CF37 1DL, Wales, UKView Profile Authors Info & Claims ACM Computing SurveysVolume 31Issue 4esDec. 1999 pp 4–eshttps://doi.org/10.1145/345966.345980Online:01 December 1999Publication History 9citation1,047DownloadsMetricsTotal Citations9Total Downloads1,047Last 12 Months3Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Evaluation of an Army Aviator's Ability to Conduct Ingress and Egress of the RAH-66 Comanche Crew Station While Wearing the Air Warrior Ensemble (2004)

The RAH-66 Comanche represented the U.S. Army's next generation state-of-the-art armed reconnaissance helicopter. Likewise, the Air Warrior aviation life support ensemble worn by Army aviators represents a significant improvement in personal clothing and equipment. However, at the intersection of the Comanche's crew stations and the bulkiness of the Air Warrior ensemble lies a potential problem: pilots have difficulty entering and leaving the crew station, especially in an emergency. This study evaluated an Army aviator's ability to conduct ingress and egress of the Comanche while wearing the Air Warrior ensemble. Several operationally relevant combinations of aircrew anthropometry, Air Warrior ensembles, and ingress-egress routes were evaluated for the front and rear crew stations. Jack human-figure modeling and motion capture technology were also used in the evaluation. Mean emergency egress times were found to be well within published military specifications. However, results show that larger males will likely have a significantly more difficult time leaving the aircraft than smaller persons, especially when clothed in the bulkiest Air Warrior configuration. Several operational and design recommendations are made. In February 2004, the Department of the Army cancelled the RAH-66 Comanche program. However, the information contained in this report can be used for ingress and egress testing of new or modified aviation systems.
Probiotics and immune health (2011)

Probiotics may provide novel approaches for both disease prevention and treatment. However, the results of clinical studies regarding probiotic application are preliminary and require further confirmation.
Using virtual data for training deep model for hand gesture recognition (2018)

Deep learning has shown real promise for the classification efficiency for hand gesture recognition problems. In this paper, the authors present experimental results for a deeply-trained model for hand gesture recognition through the use of hand images. The authors have trained two deep convolutional neural networks. The first architecture produces the hand position as a 2D-vector by input hand image. The second one predicts the hand gesture class for the input image. The first proposed architecture produces state of the art results with an accuracy rate of 89% and the second architecture with split input produces accuracy rate of 85.2%. In this paper, the authors also propose using virtual data for training a supervised deep model. Such technique is aimed to avoid using original labelled images in the training process. The interest of this method in data preparation is motivated by the need to overcome one of the main challenges of deep supervised learning: using a copious amount of labelled data during training.
Policy-Based Resource Management and Service Provisioning in GMPLS Networks (2006)

Emerging network applications tend to be built over heterogeneous network resources spanning multiple management domains. Many such applications have dynamic demands for dedicated, deterministic, high-bandwidth connections. The generalized multi-protocol label switching (GMPLS) networks under development can address these kinds of demands by using policy-based resource management and service provisioning technologies. In this paper, we present the architecture and implementation for policy-based resource management and service provisioning as part of the work on the NSF funded dynamic resource allocation via GMPLS optical networks (DRAGON) Project. This work captures several critical features of service-oriented GMPLS networks, including a) collaborative interdomain resource management; b) interdomain end-to-end path computation; c) advance scheduled provisioning; and d) authentication, authorization and accounting (AAA). These features rely on the capability of exchanging and coordinating resource and policy information among multiple participating domains. In pursuit of this capability, we propose a three-dimensional (3D) resource computation model (RCM). The three broad dimensions of this model are traffic engineering (TE) constraints, time schedule constraints, and AAA policy constraints. The 3D RCM facilitates policy based resource allocation based on many specific constraints within these three broad categories. Based on this model we describe our approach to GMPLS interdomain end-to-end path computation, advance scheduled provisioning, and AAA policy based provisioning, respectively. Our current DRAGON implementation status is also reported in this paper.
Design and implementation of anti low-frequency noise in visible light communications (2017)

With the increasing popularity of light emitting diodes (LEDs), visible light communication (VLC) systems provide an attractive alternative method for wireless communication. To reduce complexity and achieve lower cost, the on-off keying (OOK) modulation has been widely adopted in implementation of VLC systems. Although the conventional minimum-voltage detection circuit can remove the interference from sunlight or ambient light, the low frequency noise problem is still unsolved. To overcome this drawback, we propose a novel OOK-based VLC receiver architecture consisting of a transimpedance amplifier, a fourth order high pass filter with Sallen-Key method, and a Schmitt trigger. Experiment results show that the proposed receiver not only can remove the interference from ambient lights, but also can reduce the interference effects from the low-frequency noise of ambient light or indoor fluorescent light.
Antioxidant and Antibacterial Activity of the Beverage Obtained by Fermentation of Sweetened Lemon Balm (Melissa officinalis L.) Tea with Symbiotic Consortium of Bacteria and Yeasts (2014)

Kombucha is a fermented tea beverage which is traditionally prepared by fermenting sweetened black or green tea (<i>Camellia sinensis</i> L.) with symbiotic consortium of bacteria and yeasts (SCOBY). In this study, lemon balm (<i>Melissa officinalis</i> L.) was used as the only nitrogen source for kombucha fermentation. During the seven-day fermentation process, pH value, titratable acidity (TA), total phenolic content, phenolic compounds, and antioxidant activity against hydroxyl (<b>˙</b>OH) and 1,1-diphenyl-2-picrylhydrazil (DPPH) radicals were measured to detect the connection between the fermentation time and antioxidant and antibacterial activities of lemon balm kombucha. Antibacterial activity of finished beverages with optimum acidity (TA=4-4.5 g/L), the value which is confirmed by long-time kombucha consumers, and enhanced acidity (TA=8.12 g/L) was tested against eleven wild bacterial strains. The results showed that lemon balm could be successfully used as an alternative to <i>C. sinensis</i> L. for kombucha fermentation. Total phenolic content and antioxidant activity against DPPH radicals of lemon balm fermentation broth were higher than those of traditional kombucha. Rosmarinic acid is the main phenolic compound of the lemon balm-based kombucha that probably provides biological activity of the beverage. Judging from the EC <sub><sup>50</sup></sub> values, kombucha beverages exhibited higher antioxidant activities compared with <i>C. sinensis</i> L. and <i>M. officinalis</i> L. infusions, which can probably be ascribed to SCOBY metabolites. Lemon balm kombucha with both optimum and enhanced acidity showed antibacterial activity, which can be primarily ascribed to acetic acid, but also to some other tea components and SCOBY metabolites.
On the use of mobile tools in everyday life (2007)

This paper explores how mobile tools are used in everyday life and investigates the issues surrounding their usage, or indeed, their lack of usage. Personal computers support us in a wide range of our desk-bound activities, but there is still relatively little use of computer-based tools in other parts of our day-to-day lives. We hypothesise that this is because certain barriers-to-use exist that discourage their use in everyday environments, namely that the tools are not readily to hand at the time of need and/or that they distract the user's attention too much from the surrounding environment or main task at hand.