gebhart/patrepeval huggingface dataset:
Increased periodic magnetic fields for traveling wave tubes (1989)

The power output of a traveling-wave tube depends strongly on the strength of the axial magnetic field that guides its electron beam. Such fields are usually less than 5.0 kOe. With conventional permanent-magnet stacks, such fields are attainable only with periodic structures with periods of the order of the working bore diameters. The axial fields resulting from such structures have root-mean-square fields of about 3.5 kOe. The authors describe two novel stacks employing magic spheres that offer root-mean-square fields that are from two to three times as great, and that afford order-of-magnitude power increases over those of the conventional structures.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A new approach to layered space-time coding and signal processing (2001)

The information-theoretic capacity of multiple antenna systems has been shown to be significantly higher than that of single antenna systems in Rayleigh-fading channels. In an attempt to realize this capacity, Foschini (1996) proposed the layered space-time architecture. This scheme was argued to asymptotically achieve a lower bound on the capacity. Another line of work has focused on the design of channel codes that exploit the spatial diversity provided by multiple transmit antennas (Tarokh et al. 1998, Hammons and Gamal 2000). In this paper, we take a fresh look at the problem of designing multiple-input-multiple-output (MIMO) wireless systems. First, we develop a generalized framework for the design of layered space-time systems. Then, we present a novel layered architecture that combines efficient algebraic code design with iterative signal processing techniques. This novel layered system is referred to as the threaded space-time (TST) architecture. The TST architecture provides more flexibility in the tradeoff between power efficiency, bandwidth efficiency, and receiver complexity. It also allows for exploiting the temporal diversity provided by time-varying fading channels. Simulation results are provided for the various techniques that demonstrate the superiority of the proposed TST architecture over both the diagonal layered space-time architecture in Foschini (1996) and the multilayering approach (Tarokh et al. (1999).
Antiviral Activity of Interferon in Rats and the Effect of Immune Suppression (1984)

The antiviral effect of interferon was studied in a number of experimental virus infections in the rat. Interferon was shown to protect rats infected with pseudorabies virus, herpes simplex virus or vesicular stomatitis virus. The antiviral activity was not inhibited by immune suppression induced by azothioprine, prednisolone or cyclosporin A treatment. Cyclophosphamide completely blocked the in vivo activity of interferon in rats.
Treatment of tumor-induced hypercalcemia: a solved problem? (2003)

Less than 25 years ago, tumor-induced hypercalcemia was often a lethal complication of cancer. Nowadays, it can be successfully and easily treated in at least 90% of the cases by rehydration and potent antiosteoclastic bisphosphonates. The standard therapy consists of the administration of 90 mg of pamidronate (Aredia Dry Powder) or more recently, 4 mg of zoledronic acid (Zometa)], which is even more efficient, at least in patients without bone metastases. Recurrent hypercalcemia is nevertheless difficult to control and antibodies against parathyroid-hormone-related protein may prove to be a useful treatment.
Effectiveness of Once-Weekly Rifapentine and Moxifloxacin Regimens against <i>Mycobacterium tuberculosis</i> in Mice (2001)

Mice infected with 1.6 x 10(7) CFU of Mycobacterium tuberculosis were treated 14 days later for 6 months with a regimen of once-weekly 10 mg of rifapentine and 75 mg of isoniazid per kg of body weight supplemented with either 150 mg of streptomycin per kg or 100 mg of moxifloxacin per kg during either both the 2-week daily initial and once-weekly continuation phases or only in the daily 2-week initial phase. On completion of treatment, all lung cultures were negative, except for three mice, each with a single colony: two whose rifapentine-isoniazid regimen was supplemented with streptomycin during the whole course of therapy and one whose rifapentine-isoniazid regimen had no initial daily phase, but was supplemented with streptomycin and moxifloxacin during the whole course of therapy. After 3 months of follow-up, positive lung cultures were obtained from 61 and 56% of mice supplemented with streptomycin during either the full course of therapy or only the daily 2-week initial phase, respectively, and 15 and 50% of mice supplemented with moxifloxacin during either the full course of therapy or only the daily 2-week initial phase, respectively. These results suggest that moxifloxacin has sterilizing activity against M. tuberculosis.
Inhibition of dynamin-dependent endocytosis increases shedding of the amyloid precursor protein ectodomain and reduces generation of amyloid β protein (2005)

The results indicate that APP is internalized by a dynamin-dependent process, and suggest that alterations in the activity of proteins that mediate endocytosis might lead to significant changes in Abeta production.
Spinal Cord Trauma (2007)

Journal of the American College of Surgeons 205(3):p 520-521, September 2007. | DOI: 10.1016/j.jamcollsurg.2007.05.017
Sequence determination and analysis of the 3' region of chicken Pro-.alpha.1(I) and Pro-.alpha.2(I) collagen messenger ribonucleic acids including the carboxy-terminal propeptide sequences (1981)

Three pro-alpha 1 collagen cDNA clones, pCg1, pCg26, and pCg54, and two pro-alpha 2 collagen cDNA clones, pCg 13 and pCg45, were subjected to extensive DNA sequence determination. The combined sequences specified the amino acid sequences for chicken pro-alpha 1 and pro-alpha 2 type I collagens starting at residue 814 in the collagen triple-helical region and continuing to the procollagen C-termini as determined by the first in-phase termination codon. Thus, the sequences of 272 pro-alpha 1 C-terminal, 260 pro-alpha 2 C-terminal, 201 pro-alpha 1 helical, and 201 pro-alpha 2 helical amino acids were established. In addition, the sequences of several hundred nucleotides corresponding to noncoding regions of both procollagen mRNAs were determined. In total, 1589 pro-alpha 1 base pairs and 1691 pro-alpha 2 base pairs were sequenced, corresponding to approximately one-third of the total length of each mRNA. Both procollagen mRNA sequences have a high G+C content. The pro-alpha 1 mRNA is 75% G+C in the helical coding region sequenced and 61% G&C in the C-terminal coding region while the pro-alpha 2 mRNA is 60% and 48% G+C, respectively, in these regions. The dinucleotide sequence pCG occurs at a higher frequence in both sequences than is normally found in vertebrate DNAs and is approximately 5 times more frequent in the pro-alpha 1 sequence than in the pro-alpha 2 sequence. Nucleotide homology in the helical coding regions is very limited given that these sequences code for the repeating Gly-X-Y tripeptide in a region where X and Y residues are 50% conserved. These differences are clearly reflected in the preferred codon usages of the two mRNAs.
Targeting MICA with therapeutic antibodies for the treatment of cancer (2013)

Meeting abstracts MICA and MICB, along with ULPBs, are ligands for the activating receptor NKG2D expressed on NK cells and subsets of T cells in Human. NKG2D ligands are induced by cellular stress and pathogen infections. Their expression is tightly regulated by complex mechanisms both at the mRNA
Design of High Power Permanent Magnet Motor With Segment Rectangular Copper Wire and Closed Slot Opening on Electric Vehicles* (2010)

Brushless permanent magnet DC motors are being manufactured and used increasingly in everything from home appliances to automobiles due to their inherent advantages. The merits of these motors could be enhanced further according to another design approach method which alters the typically used winding parts for low to medium power range motors. This paper deals with the high power brushless DC motor used for traction in a 48 V golf cart system. The stator is designed with segment rectangular copper winding to maximize output power within its limited dimensions. In the design process, the closed slot opening and slot-pole combination are investigated and compared in terms of efficiency and input current density. The developed motor obtained about 120% greater power density per volume compared to a commercial motor with round winding coils at similar efficiency and variable speed range.
Blood lead and mercury levels in pregnant women in the United States, 2003-2008. (2010)

Chemical exposure during pregnancy is potentially harmful to the developing fetus, as the placenta cannot protect against heavy metals such as lead and mercury. Cord blood mercury levels have been associated with childhood cognitive function. High levels of lead exposure during pregnancy have been associated with adverse birth outcomes and, in some studies, with lower cognitive function test scores in childhood; relatively low lead levels have recently been associated with a small risk of decreased birthweight. While intervention for pregnant women with blood lead levels greater than or equal to 5 μg/dL has been recommended, no comparable recommendation for blood mercury in pregnant women has been established.This report presents geometric mean lead and mercury blood levels of pregnant women in the United States based on using the 2003-2008 National Health and Nutrition Examination Surveys (NHANES). Throughout this report, the term mean refers to the geometric mean.
A 5-μm/sup 2/ full-CMOS cell for high-speed SRAMs utilizing a optical-proximity-effect correction (OPC) technology (2002)

A 5.01-/spl mu/m/sup 2/ full-CMOS SRAM cell using a 0.28-/spl mu/m design rule has been developed and the cell operation at as low as 0.6 V was confirmed. This cell has been designed not only to be small but also to be widened bitline pitch for reduction of bitline delay. To realize this cell, optical-proximity-effect correction (OPC) and some technologies for cell-size reduction have been adopted. In addition, glue layer wiring (GLAW) for the local interconnection has been used in order to simplify the process.
Real-time Tetrahedral Volume Editing Accounting for Discontinuities (2006)

Geological systems can be represented as unstructured tetrahedral grids where faults are topological discontinuities in the volume and each fault block is a connected component. These grids are built from interpretations of seismic and borehole data. Obtaining additional data or new interpretations can point out errors in the tetrahedralised volume. When the location of a fault is slightly off, a new tetrahedralised volume has to be created from scratch. Directly editing the volume would be more effective and comfortable. A free-form deformation technique was developed to implement this interaction. The deformation is confined to a zone around the fault to be edited. Volume deformation is achieved by dragging control points; the geometry of the volume in the vicinity of the discontinuity is updated in realtime. A constraint maintains model consistency throughout editing by preventing tetrahedrons from flipping over. A smoothness constraint distributes the displacement in the whole active region.
Spectrophotometric Estimation of 3-OH L-Kynurenine O-β-Glucoside in the Human Lens1 (1981)

A low molecular weight yellow substance with absorption maxima at 228, 263, and 365 nm was separated from the water soluble fraction in human lens by gel filtration on a Sephadex G-15 column. The absorption spectrum of the yellow substance shifted to that of 3-OH L-kynurenine (absorption maxima; 228, 267, and 368 nm) after hydrolysis with β-glucosidase [EC 3.2.1.21]. Concomitantly, its absorbances at 228 and 365 nm decreased; the spectra of both compounds intersect at 235, 249, 263, 305, and 387 nm (isosbestic points). The hydrolytic product of the yellow substance was shown to contain 3-OH L-kynurenine (by amino acid analysis) and glucose (by gas chromatography). The yellow substance was thus identified as 3-OH L-kynurenine O-β-glucoside. Since the molar extinction coefficient of authentic 3-OH L-kynurenine was found to be 3650 M−1* cm−1 at 368 nm, the molar extinction coefficient of the glucoside can be calculated to be 4340 M−1, cm−1 at 365 nm from the absorbance ratio of the glucoside at 365 nm and of 3-OH L-kynurenine at 368 nm to the absorbances at the isosbestic points. By employing the molar extinction coefficient thus obtained, the amount of 3-OH L-kynurenine O-β-glucoside isolated from human lens was estimated. The glucoside content in whole lens and the specific content, expressed as umol per g lens protein, both decrease with age. In particular, the specific content decreases linearly with age over the period from birth to the age of 30–40, and subsequently it seems to remain at a constant level.
Multispectral Imaging of T and B Cells in Murine Spleen and Tumor (2016)

Recent advances in multiplex immunohistochemistry techniques allow for quantitative, spatial identification of multiple immune parameters for enhanced diagnostic and prognostic insight. However, applying such techniques to murine fixed tissues, particularly sensitive epitopes, such as CD4, CD8α, and CD19, has been difficult. We compared different fixation protocols and Ag-retrieval techniques and validated the use of multiplex immunohistochemistry for detection of CD3(+)CD4(+) and CD3(+)CD8(+) T cell subsets in murine spleen and tumor. This allows for enumeration of these T cell subsets within immune environments, as well as the study of their spatial distribution.
System response to automated grid methods (1990)

Digital image processing and pattern recognition have become important tools in experimental stress analysis. Fringe interpretation and digital autocorrelation are the two prominent examples where digital image processing has significantly influenced experimental research. This paper discusses the use of digital image processing in concert with the grid method. Presented here is a start-to-finish analysis of grid point tracking with image acquisition hardware and pattern recognition software. A mathematical model, which is based on experimentally controllable parameters, is used to simulate the video camera and analog-to-digital conversion. A simple centroid algorithm is used to track the grid points. The model results, which are reaffirmed by rigid body motion tests, show that the fill factor, signal-to-noise ratio, and grid spot diameter govern the accuracy of this automated grid method. Finally, the model shows that the intensity profile of the individual grid spots has a significant impact on the maximum allowable grid frequency, camera field of view, and the overall acëuracy of automated grid methods.
Incentives for the reuse of electric vehicle batteries for load-shifting in residences (2015)

With growing uncertainty in electricity prices and rising concern about climate change, there is increased need to reduce both energy costs and carbon emissions. One way to accomplish these goals is through load-shifting provided by the reuse of the large lithium ion batteries currently found in most electric vehicles (EVs). When used as a load-shifting device, a used EV battery has the potential to help a residential user reduce the cost of their electric bill and contribute to a reduction in emissions while also laying groundwork for the future 'smart grid'. To study this, a MatLAB model is developed and implemented to examine the use of an EV battery that is reused for peak shifting in a typical household. The results of the simulation for number of different incentive types are compared using a multi-criteria decision making approach to arrive at a policy choice that satisfies both government and consumer stakeholders.
[Results of various operations for syndactylia (follow-up studies and statistical evaluation of 101 primary operations)]. (1978)

Theodore Roosevelt writes to David Craig Montgomery and Fred Stone requesting four tickets to their new play at the Global Theatre. Edith Kermit Carow Roosevelt attempted to procure tickets at the box office but was unsuccessful.
Paracrine actions of IGF binding proteins. (1991)

The paracrine mode of action for IGFs has been hypothesized on the basis of the finding that these peptides are synthesized ubiquitously. As IGFs circulate in very high concentrations (nearly 1 mg/l) they should have an endocrine function; moreover since the liver seems to be responsible for most of the circulating IGF-I it should be recognized that the basis of the "hormonal" IGF-I residues in the liver, whereas the extrahepatic synthesis provides support for local paracrine or autocrine actions. According to the endocrine hypothesis, the liver, which lacks IGF-I receptors, produces both IGF-I and IGF binding protein (IGFBP) and, possibly, the acid-labile subunit. All these components combine in the circulation, and only free IGF-I or small molecular weight complexes cross the capillary wall and reach the target cells. The paracrine hypothesis is based on the fact that fibroblasts are able to synthesize both IGF peptides and IGFBP, whereas keratinocytes are not, although they possess IGF receptors and are sensitive to IGF action. Since affinity of BP3 (which seems to be produced by peripheral fibroblasts) for IGF-I is higher than that of fibroblasts and, to a lesser degree, of keratinocytes, it is likely that IGF-I released from fibroblasts preferentially binds to BP3; the BP3-IGF-I complex reduces the autocrine effects on fibroblasts and preferentially directs the peptide binding to keratinocytes. The secretion of both IGFs and of IGF carrier proteins has been reported in several neoplastic epithelial cell lines.(ABSTRACT TRUNCATED AT 250 WORDS)
Mobilization of copper(II) from plasma components and mechanisms of hepatic copper transport (1984)

The effects of plasma Cu(II) ligands on the kinetics of Cu(II) transport by rat liver parenchymal cells were determined to examine how Cu(II) is mobilized from plasma and transported into liver cells. Albumin markedly inhibited Cu(II) uptake at Cu(II)-to-albumin molar ratios of 3:1 or less. Kinetic analyses showed that albumin inhibits Cu(II) uptake by reducing the concentration of free Cu(II) in solution. Under conditions of excess albumin to Cu(II), histidine facilitated albumin-inhibited uptake of Cu(II). Threonine, glutamine, and most other amino acids were without effect. Moreover, the facilitation effect of a low-molecular-weight plasma fraction (less than or equal to 5,000) was largely accounted for by its histidine concentration. The tripeptide Gly-His-Lys also inhibited Cu(II) uptake into hepatocytes by the same mechanism as albumin. The inhibitory effects of albumin and Gly-His-Lys were additive with or without histidine. The active species in the Cu(II), albumin, and histamine mixtures was shown to be the His2Cu(II) complex. Vmax for this complex was identical to the Vmax for free Cu(II), but the Km was slightly higher [15 microM vs. 11 microM for free Cu(II)]. Concurrent determinations of [3H]-histidine and 64Cu(II) uptake showed that histidine was not transported with Cu(II) from His X Cu(II) or His2Cu(II) complexes. The data are consistent with histidine mobilizing Cu(II) from albumin by competing for Cu(II), interaction of the His2Cu(II) complex with the putative hepatic copper transport protein, and transport of copper as free ionic copper.
Trouble with Megasessions and Dense Packing (1995)

Dense packing and megasessions are technically difficult and stress the most experienced team. I have given them a lot of press and I worried that their rapid spread was partly my fault. I personally have had problems with poor growth in dense packing and I have stopped, or at least I have not
Antigenic relatedness and N-terminal sequence homology define two classes of periplasmic flagellar proteins of Treponema pallidum subsp. pallidum and Treponema phagedenis (1988)

The periplasmic flagella of many spirochetes contain multiple proteins. In this study, two-dimensional electrophoresis, Western blotting (immunoblotting), immunoperoxidase staining, and N-terminal amino acid sequence analysis were used to characterize the individual periplasmic flagellar proteins of Treponema pallidum subsp. pallidum (Nichols strain) and T. phagedenis Kazan 5. Purified T. pallidum periplasmic flagella contained six proteins (Mrs = 37,000, 34,500, 33,000, 30,000, 29,000, and 27,000), whereas T. phagedenis periplasmic flagella contained a major 39,000-Mr protein and a group of two major and two minor 33,000- to 34,000-Mr polypeptide species; 37,000- and 30,000-Mr proteins were also present in some T. phagedenis preparations. Immunoblotting with monospecific antisera and monoclonal antibodies and N-terminal sequence analysis indicated that the major periplasmic flagellar proteins were divided into two distinct classes, designated class A and class B. Class A proteins consisted of the 37-kilodalton (kDa) protein of T. pallidum and the 39-kDa polypeptide of T. phagedenis; class B included the T. pallidum 34.5-, 33-, and 30-kDa proteins and the four 33- and 34-kDa polypeptide species of T. phagedenis. The proteins within each class were immunologically cross-reactive and possessed similar N-terminal sequences (67 to 95% homology); no cross-reactivity or sequence homology was evident between the two classes. Anti-class A or anti-class B antibodies did not react with the 29- or 27-kDa polypeptides of T. pallidum or the 37- and 30-kDa T. phagedenis proteins, indicating that these proteins are antigenically unrelated to the class A and class B proteins. The lack of complete N-terminal sequence homology among the major periplasmic flagellar proteins of each organism indicates that they are most likely encoded by separate structural genes. Furthermore, the N-terminal sequences of T. phagedenis and T. pallidum periplasmic flagellar proteins are highly conserved, despite the genetic dissimilarity of these two species.
Structure and vibrational spectroscopy of the water dimer using quantum simulation (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure and vibrational spectroscopy of the water dimer using quantum simulationD. F. Coker and R. O. WattsCite this: J. Phys. Chem. 1987, 91, 10, 2513–2518Publication Date (Print):May 1, 1987Publication History Published online1 May 2002Published inissue 1 May 1987https://pubs.acs.org/doi/10.1021/j100294a015https://doi.org/10.1021/j100294a015research-articleACS PublicationsRequest reuse permissionsArticle Views545Altmetric-Citations137LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts