gebhart/patrepeval huggingface dataset:
Effect of Wick Characteristics on the Thermal Performance of the Miniature Loop Heat Pipe (2009)

Two phase heat transfer devices based on the miniature version of loop heat pipe (LHP) can provide very promising cooling solutions for the compact electronic devices due to their high heat flux management capability and long distance heat transfer with minimal temperature losses. This paper discusses the effect of the wick properties on the heat transfer characteristics of the miniature LHP. The miniature model of the LHP with disk-shaped evaporator, 10 mm thick and 30 mm disk diameter, was designed using copper containment vessel and water as the working fluid, which is the most acceptable combination in electronic cooling applications. In the investigation, wick structures with different physical properties including thermal conductivity, pore radius, porosity, and permeability and with different structural topology including monoporous or biporous evaporating face were used. It was experimentally observed that copper wicks are able to provide superior thermal performance than nickel wicks, particularly for low to moderate heat loads due to their low heat conducting resistance. With monoporous copper wick, maximum evaporator heat transfer coefficient (hev) of 26,270 W/m2 K and evaporator thermal resistance (Rev) of 0.06–0.10°C/W were achieved. For monoporous nickel wick, the corresponding values were 20,700 W/m2 K for hev and 0.08–0.21°C/W for Rev. Capillary structure with smaller pore size, high porosity, and high permeability showed better heat transfer characteristics due to sufficient capillary pumping capability, low heat leaks from evaporator to compensation chamber and larger surface area to volume ratio for heat exchange. In addition to this, biporous copper wick structure showed much higher heat transfer coefficient of 83,787 W/m2 K than monoporous copper wick due to improved evaporative heat transfer at wick wall interface and separated liquid and vapor flow pores. The present work was able to classify the importance of the wick properties in the improvement of the thermal characteristics for miniature loop heat pipes.
Potent aquaretic agent. A novel nonpeptide selective vasopressin 2 antagonist (OPC-31260) in men. (1993)

Solute-free water diuretics (aquaretics) by antagonizing hydrosmotic vasopressin receptors (V2) may be useful in treating water-retaining diseases. The effects of intravenous administration of a newly developed nonpeptide, selective V2 antagonist, OPC-31260, at doses ranging from 0.017 to 1.0 mg/kg to groups of healthy, normally hydrated men were compared with those of 0.33 mg/kg furosemide and placebo. OPC-31260 increased the hypotonic urine volume dose dependently for the first 4 h, while furosemide induced sodium diuresis for 2 h. The absolute increase in the cumulative response in the urine to the highest doses of OPC-31260 was not significantly different from that to furosemide. The higher doses of OPC-31260 rapidly lowered urine osmolality for 2 h, particularly between minutes 15 and 45 (e.g., 1.0-mg/kg dose: 63 +/- 2 mOsm/kg in urine collected between minutes 30 and 45). In a marked hypotonic diuresis, mean free water clearance of the 4-h urine increased dose proportionally into the positive range, reaching 1.80 +/- 0.21 ml/min at 1.0 mg/kg. Whereas furosemide induced marked Na and K diuresis, OPC-31260 increased urinary Na excretion only slightly. At 4 h, 0.75 and 1.0 mg/kg of OPC-31260 almost doubled the plasma arginine vasopressin; and the higher doses increased plasma osmolality and plasma Na slightly, but did not alter plasma K, blood pressure, or heart rate. OPC-31260 thus safely induced a potent aquaretic effect in men.
Predicting diabetic ketoacidosis in children by measuring end‐tidal CO<sub>2</sub> via non‐invasive nasal capnography (2007)

Nasal capnography in conjunction with clinical assessment is predictive of DKA. Further research into this area with larger numbers could help validate ETCO(2) as a screening tool for DKA in the emergency department.
Type V collagen as the target for type‐3 fimbriae, enterobacterial adherence organelles (1990)

Tissue-binding specificity of the type-3 fimbriae of pathogenic enteric bacteria was determined using frozen sections of human kidney. A wild-type Klebsiella sp. strain and the recombinant strain Escherichia coli HB101(pFK12), both expressing type-3 fimbriae, as well as the purified type-3 fimbriae effectively bound to sites at or adjacent to tubular basement membranes, Bowman's capsule, arterial walls, and the interstitial connective tissue. Bacterial adherence to kidney was decreased after collagenase treatment of the tissue sections. Recombinant strains expressing type-3 fimbriae specifically adhered to type V collagen immobilized on glass slides, whereas other collagens, fibronectin or laminin did not support bacterial adherence. In accordance with these findings, specific binding of purified type-3 fimbriae to immobilized type V collagen was demonstrated. Specific adhesion to type V collagen was also seen with the recombinant strain HB101(pFK52/pDC17), which expresses the mrkD gene of the type-3 fimbrial gene cluster in association with the pap-encoded fimbrial filament of E. coli, showing that the observed binding was mediated by the minor lectin (MrkD) protein of the type-3 fimbrial filament. The interaction is highly dependent on the conformation of type V collagen molecules since type V collagen in solution did not react with the fimbriae. Specific binding to type V collagen was also exhibited by type-3 fimbriate strains of Yersinia and Salmonella, showing that the ability to use type V collagen as tissue target is widespread among enteric bacteria.
3D Object Dense Reconstruction from a Single Depth View. (2018)

In this paper, we propose a novel approach, 3D-RecGAN++, which reconstructs the complete 3D structure of a given object from a single arbitrary depth view using generative adversarial networks. Unlike existing work which typically requires multiple views of the same object or class labels to recover the full 3D geometry, the proposed 3D-RecGAN++ only takes the voxel grid representation of a depth view of the object as input, and is able to generate the complete 3D occupancy grid with a high resolution of 256^3 by recovering the occluded/missing regions. The key idea is to combine the generative capabilities of autoencoders and the conditional Generative Adversarial Networks (GAN) framework, to infer accurate and fine-grained 3D structures of objects in high-dimensional voxel space. Extensive experiments on large synthetic datasets and real-world Kinect datasets show that the proposed 3D-RecGAN++ significantly outperforms the state of the art in single view 3D object reconstruction, and is able to reconstruct unseen types of objects.
Cardiac troponin T is a sensitive, specific biomarker of cardiac injury in laboratory animals. (1997)

A reliable serum assay that can discriminate between cardiac and skeletal muscle injury is not available for diagnostic use in laboratory animals. We tested and supported the hypotheses that serum cardiac troponin T (cTnT) was widely applicable in laboratory animals as a biomarker of cardiac injury arising from various causes; that it increased in proportion to severity of cardiac injury; and that it was more cardiospecific than creatine kinase (CK) or lactate dehydrogenase (LD) isozyme activities. In canine and rat models of myocardial infarction, cTnT concentration increased 1,000- to 10,000-fold and was highly correlated with infarct size within 3 h of injury. Serum CK and LD isozymes were substantially less effective biomarkers and, in contrast to cTnT, were ineffective markers in the presence of moderate skeletal muscle injury, with resulting serum CK activity > 5,000 U/L. Using these animal models, and mouse and ferret models, we also showed cTnT to be an effective biomarker in doxorubicin cardiotoxicosis, traumatic injury, ischemia, and cardiac puncture. Reference range serum concentrations for all species were at the detection limit of the assay, except those for mice, in which they were slightly increased, possibly because mice were used to generate assay monoclonal antibodies. We conclude that cTnT is a powerful biomarker in laboratory animals for the sensitive and specific detection of cardiac injury arising from various causes.
Preparation and investigation of laser ablated PZT, PLZT and PbMg<sub>1/3</sub>Nb<sub>2/3</sub>O<sub>3</sub>(PMN) ferroelectric films (1994)

Abstract Epitaxial thin films of Pb(ZrxTi1-x)O3, Pb1-xLax(ZryTiz)1–(x/4)O3, and PbMg1/3Nb2/3O3 were created by pulsed laser deposition on YBa2Cu3O7-x coated (100)SrTiO3 and (110)SrTiO3 substrates. Film properties were characterized by XRD, RBS and SEM. The remanent polarization and coercive field of the PZT(0.52, 0.48) film were 42 μCcm−2 and 55 kVcm−1. The change of film properties with deposition temperature were studied.
Transcriptional Regulation of Serum Amyloid A1 Gene Expression in Human Aortic Smooth Muscle Cells Involves CCAAT/Enhancer Binding Proteins (C/EBP) and is Distinct From HepG2 Cells* (2002)

Regulation of acute-phase serum amyloid A (A-SAA) synthesis by proinflammatory cytokines and steroid hormones in human aortic smooth muscle cells (HASMCs) is distinct from that in HepG2 cells. To study the cis- and trans-activating promoter element involved in the SAA1 gene expression by HASMCs and HepG2 cells, we constructed plasmid vectors for luciferase reporter gene assay with varying lengths of SAA1 upstream regulatory region (up to 1431 bp), and examined their response to proinflammatory cytokines and/or steroid hormones. The corresponding vectors with the SAA4 upstream regulatory region served as controls. The presence of proposed transcriptional regulatory factors binding to these regions was confirmed immunohistochemically. The sequences of 1478 and 1836 bp of the SAA1 and SAA4 5'-flanking regions were determined, respectively. SAA1 promoter transcription in cultured HASMCs was upregulated not by proinflammatory cytokines, but rather by glucocorticoids. This differed from HepG2 cells, in which SAA1 promoter transcription was upregulated synergistically by proinflammatory cytokines and glucocorticoids. The promoter activity of a series of truncated SAA1 promoter constructs measured using the reporter gene assay showed that the 5'-region from -252 to -175, containing a consensus site for CCAAT/enhancer binding proteins alpha,beta (C/EBPalpha,beta), was essential for SAA1 induction in HASMCs. In HepG2 cells, the 5'-region from -119 to -79, containing a nuclear factor kappa-B (NFkappaB) consensus sequence, was essential for the induction. The functional significance of the C/EBP site as indicated by the immunohistochemical result was that in HASMCs anti-C/EBPbeta reactivity was shifted from the cytoplasm to the nuclei. We have, therefore, demonstrated that the region containing the C/EBPalpha,beta consensus binding site between the bases -252 and -175 is important for the glucocorticoid-induced SAA1 gene expression in HASMCs but not in HepG2 cells.
Herpes Virus Production as a Marker of Repair in Ultra-violet Irradiated Human Skin Cells of Different Origin (1979)

SummaryConfluent cultures of human skin fibroblasts were irradiated with ultra-violet light 0 to 48 hours before infection with herpes simplex virus type 1 (HSV). The one-cycle viral yield was measured. Different responses were obtained according to the origin of the host cells. (1) Cells from three normal donors showed a dose-dependent recovery of HSV production during the 36–40 hours following U.V. exposure. The recovery was maximal for a dose at which a plateau level of unscheduled DNA synthesis (UDS) was reached (24 J m−2). (2) In a xeroderma pigmentosum (XP) heterozygote line from a mother of XP children, the level of UDS after irradiation up to 48 J m−2 was normal whereas the extent of recovery of HSV production capacity was lower than that of the normal lines. (3) In strains from two cases of XP children, with a normal UDS (XP variants), the recovery process was slowed down and its extent was lower than in normal or XP heterozygote cells. (4) Excision-deficient XP strains from eight cases of XP children presented either no recovery (two strains having the lowest UDS, <2 per cent) or a small recovery, the extent of which was in good agreement with the corresponding level of UDS (between 5 and 30 per cent). Measurement of this recovery seems to be a very sensitive assay for detecting differences in the repair abilities of U.V.-irradiated human skin cells of various origins.
Measurement of Vapor Pressures by Means of Matched Thermistors. (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMeasurement of Vapor Pressures by Means of Matched Thermistors.A. P. Brady, Harriette Huff, and J. W. McBainCite this: J. Phys. Chem. 1951, 55, 2, 304–311Publication Date (Print):February 1, 1951Publication History Published online1 May 2002Published inissue 1 February 1951https://pubs.acs.org/doi/10.1021/j150485a017https://doi.org/10.1021/j150485a017research-articleACS PublicationsRequest reuse permissionsArticle Views89Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
UWB communication and networking systems with chaotic oscillator for low rate WPAN (2006)

This paper focused on the chaotic UWB (ultrawide band) systems for low rate WPAN. According to the UWB signal generation methods, there are three types of signals such as impulse, chaos, and chirp suggested by IEEE WPAN TG4a. The chaotic UWB signal generation has advantage of arbitrary wide band pulse shape. Based on chaotic signal, chaotic UWB communication systems are implemented, which is composed of RF blocks and digital blocks. And then they are interconnected as star topology with coordinator and several end nodes and shown the functions of image transferring.
Molecular and spectroscopic properties of a polarizer based on a block copolymer of vinylalcohol and acetylene (2000)

The preparation of a high efficiency polarizer derived from the block copolymer, poly(vinylalcohol-b-acetylene) will be described. The orientations of the polyacetylene chromophore and the polyvinylalcohol matrix have been analyzed by polarized UV/Vis and FTIR spectroscopy, respectively. For moderately stretched films (L/Lo = 3.0-7.0), the degree of orientation for the polyacetylene segments greatly exceeds that predicted from a simple, pseudoaffine deformation model. For the visible spectral region, dichroic ratios in the range of 60 to 100 are easily achieved, thus permitting films of this polymer to function as a high efficiency, polarizing optical element. Data from a series of sample tilting experiments utilizing polarized UV/Vis radiation are consistent with the polyacetylene segments being distributed uniaxially about the stretching direction. However, analogous experiments in the infrared indicate that the PVA matrix has significant biaxial character. Other novel characteristics of this polarizer will be discussed, such as its thermal and chemical stability.
Naive tumor-specific CD4+ T cells differentiated in vivo eradicate established melanoma (2010)

In vitro differentiated CD8(+) T cells have been the primary focus of immunotherapy of cancer with little focus on CD4(+) T cells. Immunotherapy involving in vitro differentiated T cells given after lymphodepleting regimens significantly augments antitumor immunity in animals and human patients with cancer. However, the mechanisms by which lymphopenia augments adoptive cell therapy and the means of properly differentiating T cells in vitro are still emerging. We demonstrate that naive tumor/self-specific CD4(+) T cells naturally differentiated into T helper type 1 cytotoxic T cells in vivo and caused the regression of established tumors and depigmentation in lymphopenic hosts. Therapy was independent of vaccination, exogenous cytokine support, CD8(+), B, natural killer (NK), and NKT cells. Proper activation of CD4(+) T cells in vivo was important for tumor clearance, as naive tumor-specific CD4(+) T cells could not completely treat tumor in lymphopenic common gamma chain (gamma(c))-deficient hosts. gamma(c) signaling in the tumor-bearing host was important for survival and proper differentiation of adoptively transferred tumor-specific CD4(+) T cells. Thus, these data provide a platform for designing immunotherapies that incorporate tumor/self-reactive CD4(+) T cells.
Monitoring Release of Neurotrophic Activity in the Brains of Awake Rats (1995)

Intracerebral microdialysis of awake rats was used to monitor the possible release of neurotrophic factors from brain cells in response to injury and excitation. Perfusates were tested with ganglia bioassays and enzyme immunoassay. Trophic activity was released after implantation of the microdialysis probe into the hippocampus but not into the striatum, as assessed by increased nerve fiber outgrowth from Remak's ganglion. Kainic acid treatment significantly increased the release of trophic activity from hippocampal sites. These findings suggest that the brain responds to mechanical injury as well as to certain excitatory stimuli by regional extracellular release of neurotrophic activity that is not identical to the actions of known neurotrophic factors.
Organization of the double-stranded rna-activated protein kinase dai and virus-associated va rnai in adenovirus-2-infected hela cells (1993)

We have examined the cellular distribution of the double-stranded RNA-activated protein kinase DAI in adenovirus 2 (Ad2)-infected and uninfected HeLa cells. In uninfected cells DAI was found to be concentrated in the cytoplasm. In addition, DAI was localized in the nucleoli and diffusely distributed throughout the nucleoplasm. Cells treated with alpha-interferon displayed a similar pattern of distribution for DAI. When RNA polymerase I activity was inhibited by the drug actinomycin D, nucleoli segregated and DAI was found to colocalize with the dense fibrillar region of the nucleoli. During mitosis, the distribution of DAI paralleled that of rRNA. In adenovirus-infected cells the localization of DAI was similar to that in uninfected interphase cells. VA RNAI was detected in Ad2-infected cells by 10-14 hours post-infection as fine dots in the nucleoplasm. By 18-24 hours post-infection, VA RNAI appeared in bigger and more abundant dots in the nucleoplasm and the cytoplasm was intensively labeled. Transient expression of the VA RNAI gene in uninfected cells resulted in a similar localization of the RNA. Our results are consistent with a role for DAI and VA RNAI in protein synthesis and suggest that DAI may play an early role in ribosome biogenesis in the nucleolus in addition to its cytoplasmic role in translation.
Single-Fiber Probe Based on Surface Enhanced Raman Scattering (SERS) (2006)

Fiber SERS probes have great potential in chemical and biological sensing. To our knowledge, there has been no demonstration of any single-fiber SERS probes where both the excitation beam and SERS signals are transmitted through the same fiber with a significant length, which is required for a flexible probe. In this paper, we report our proof-of-concept demonstration of a single-fiber SERS probe with a 1 m long fiber. We demonstrate various configurations of the fiber probe, where the SERS substrate is coated on either a side-polished or end-polished fiber surface. While the side-polished fibers provide a large platform for signal generation, the end polished fibers are easy to manipulate and can transmit SERS signals back through the fiber. In our experiments, we have successfully detected SERS signals both at the end where the fiber is polished and coated with the SERS substrate and at the end where the excitation light is coupled into the fiber, using R6G as a testing sample
Advances in Understanding Plant Viruses and Virus Diseases (2000)

▪ Abstract Plant viruses have had an impact on the science of virology and on plant pathology ever since the virus concept was discovered with Tobacco mosaic virus at the end of the nineteenth century. In this review, we highlight those discoveries. We have divided plant virus research into a "Classical Discovery Period" from 1883-1951 in which the findings were very descriptive; an "Early Molecular Era" from 1952 to about 1983, in which information was developed that described further properties of the viruses, aided by the development of a number of salient techniques; and the "Recent Period" from 1983 to the present, when techniques have been developed to modify plant virus genomes, to detect nonstructural gene products, to determine the functions of viral gene products, and to transform plants to elicit novel forms of resistance to viral diseases. In this period, plant virology has played a significant role in formulating an understanding of the mechanisms of gene silencing and recombination, plasmodesmatal function, systemic acquired resistance, and in developing methods for pathogen detection. We also attempt to predict the direction plant virology will take in the future.
A volumetric CMUT-based ultrasound imaging system simulator with integrated reception and &#x003BC;-beamforming electronics models (2014)

In modern ultrasound imaging devices, two-dimensional probes and electronic scanning allow volumetric imaging of anatomical structures. When dealing with the design of such complex 3-D ultrasound (US) systems, as the number of transducers and channels dramatically increases, new challenges concerning the integration of electronics and the implementation of smart micro-beamforming strategies arise. Hence, the possibility to predict the behavior of the whole system is mandatory. In this paper, we propose and describe an advanced simulation tool for ultrasound system modeling and simulation, which conjugates the US propagation and scattering, signal transduction, electronic signal conditioning, and beamforming in a single environment. In particular, we present the architecture and model of an existing 16-channel integrated receiver, which includes an amplification and micro-beamforming stage, and validate it by comparison with circuit simulations. The developed model is then used in conjunction with the transducer and US field models to perform a system simulation, aimed at estimating the performance of an example 3-D US imaging system that uses a capacitive micromachined ultrasonic transducer (CMUT) 2-D phased-array coupled to the modeled reception front-end. Results of point spread function (PSF) calculations, as well as synthetic imaging of a virtual phantom, show that this tool is actually able to model the complete US image reconstruction process, and that it could be used to quickly provide valuable system-level feedback for an optimized tuning of electronic design parameters.