gebhart/patrepeval huggingface dataset:
Alendronate Reduces Periprosthetic Bone Loss After Uncemented Primary Total Hip Arthroplasty: A Prospective Randomized Study (2001)

Periprosthetic bone loss, especially in the proximal part of the femur, is common after cemented and uncemented total hip arthroplasty (THA). Bone loss can be progressive and, in the extreme, may threaten survival of the prosthesis. To study whether alendronate therapy can reduce bone loss adjacent to prostheses, 13 uncemented primary THA patients were randomized to the study. They received 10 mg alendronate + 500 mg calcium (n = 8) or 500 mg calcium only (n = 5) daily for 6 months follow-up after THA. Periprosthetic bone mineral density (BMD) was measured with dual energy X-ray absorptiometry (DXA). Decreases in periprosthetic BMD in the alendronate-treated group were lower compared with the changes in the calcium-only group in the same regions of interest at the same follow-up time. In the proximal femur, the mean BMD decrease was 17.1% in the calcium-only group, whereas in the alendronate-treated group the decrease was only 0.9% (p = 0.019). The mean periprosthetic BMD change was also significantly different in the total periprosthetic area between the study groups at the end of the follow-up (calcium-only group -9.9% vs. alendronate-treated group -2.6%; p = 0.019). Alendronate therapy led to a significant reduction in periprosthetic bone loss after primary uncemented THA compared with the changes found in patients without therapy. This kind of bone response may improve the support of the prosthesis and may result in better survival of the prosthesis. However, in this study the follow-up time was too short and the study population was too small to make any long-term conclusions as to the prognosis for THA patients treated with alendronate.
Resonant Photoemission Spectroscopy of the Cathode Material Li<sub><i>x</i></sub>FePO<sub>4</sub> for Lithium Ion Battery (2011)

The change of Fe 3d states accompanied with the Li intercalation/deintercalation process has been successfully revealed by resonant photoemission spectroscopy. The main peak shift and expansion of Fe 3d bands through the Li deintercalation reflect the strong hybridization between Fe 3d states and O 2p states as the Fe–O bond lengths decrease. From the antiresonance spectra, O 2p partial density of states also changes, suggesting the interaction between Fe and O atoms still remains in LiFePO4. Furthermore, density functional theory calculations results strongly support these experimental results. The framework structure of LiFePO4 is more suitable than that of LiCoO2 for the good rechargeable battery, because the change of the electronic structure in LiFePO4 valence band is rather small because of the strong covalent P–O bond.
Determination of adriamycin by enzyme immunoassay. (1983)

A solid phase immunoassay for the determination of adriamycin has been developed. Specific antibody against adriamycin was raised in rabbits after coupling adriamycin to bovine serum albumin. beta-D-Galactosidase labelled adriamycin was prepared by m-maleimidobenzoyl-N-hydroxysuccinimide ester (MBS) as a coupling reagent. This assay system followed the double antibody solid phase method for the B/F separation of antibody-bound and free adriamycin. By this method, from 0.5 to 100 ng of adriamycin could be detected. Using this assay system, drug levels were determined in serum of mice, following administration of adriamycin in a single dose of 15 mg/kg i.p., the peak appearing at 20 min after administration. The change of serum levels was found to be biphasic, and the half-life of beta-phase was about 5 h.
A novel H.264 SVC encryption scheme for secure bit-rate transcoding (2009)

This paper presents a novel architecture for the secure delivery of encrypted H.264 SVC bitstreams. It relies on a block cipher and stream cipher used in a novel way that would allow an intermediary transcoder to truncate the bitstream to the appropriate bit-rate without decrypting the data. The system, called SVC-sec, is compared to other architectures presented in the literature and it is shown that SVC-sec offers many benefits, particularly when used with FGS streams.
Specificity of antibodies against Neisseria gonorrhoeae that stimulate neutrophil chemotaxis. Role of antibodies directed against lipooligosaccharides. (1987)

Five strains each of Neisseria gonorrhoeae sensitive or resistant to complement (C) dependent killing by normal human serum (NHS) were examined for their ability to stimulate chemotaxis of polymorphonuclear leukocytes (PMNs) after preincubation with NHS; or IgM or IgG derived from NHS. Serum-sensitive N. gonorrhoeae stimulated C-dependent chemotaxis when opsonized with IgM, but not IgG, however, serum-resistant strains, taken as a whole, failed to promote chemotaxis when opsonized with either isotype. IgM titers in NHS against lipooligosaccharide (LOS) antigens from individual serum-sensitive, but not serum-resistant strains, correlated with the magnitude of chemotaxis generated by the corresponding opsonized strains (r = 0.99). Western blots demonstrated that IgM and IgG from NHS recognized different antigenic determinants on LOS from serum-sensitive gonococci. IgM from NHS immunopurified against serum-sensitive LOS accounted for two-thirds of the chemotaxis promoting activity present in whole serum. IgG titers in NHS against LOS antigens from individual serum-resistant strains also correlated with magnitude of chemotaxis generated by the corresponding opsonized strains (r = 0.87), although most opsonized serum-resistant strains did not generate significantly higher magnitudes of chemotaxis than controls. In contrast, a serum-resistant isolate from a patient with disseminated gonococcal infection (DGI) stimulated chemotaxis when opsonized with IgG obtained from the patient's convalescent serum. By Western blot, convalescent IgG antibody recognized an additional determinant on serum-resistant LOS not seen by normal IgG.
Formation of Hydrogen Peroxide by Group N Streptococci and Its Effect on Their Growth and Metabolism (1970)

The formation of hydrogen peroxide by group N streptococci was found to occur through the action of a reduced nicotinamide adenine dinucleotide (NADH) oxidase which catalyzed the oxidation of NADH by molecular oxygen. The enzyme was activated by flavine adenine dinucleotide. Whereas some of the hydrogen peroxide formed was removed through the action of an NADH peroxidase, sufficient accumulated in media to inhibit the growth, respiration, and viability of these organisms. The amount of hydrogen peroxide which accumulated varied among strains, and this variation could be related to differences in the properties of the NADH oxidase present.
Network Interoperability Program (2002)

The increased use of the evolving commercial infrastructure places special constraints on the development of security products. The Interoperability Program is an umbrella effort to develop interoperability requirements for the family of encryption products providing the security of the network infrastructure. The initial output of this effort is the Interoperability Functional Requirements Criteria. The document was created to provide guidelines and requirements on classes of security products which will operate over the evolving commercial infrastructure. It was developed by a working group including representatives from DOD and commercial companies. Encryption classes were defined at the link, network and application layers. Based upon the expected evolution of the commercial architecture approaches were developed to both provide heterogeneity of equipment and extend transparency of needed security services across all layers. Important areas of inclusion in the specification are: (1) the establishment of the Internet Security Association and Key Management Protocol (ISAKMP) as the security management protocol, (2) definition of a transition from the Security Association Management Protocol (ISAMP) to ISAKMP, and (3) the establishment of an interpretable Domain of Interpretation (DOI). Along with this, common encryption data handling and voice algorithms were defined to insure a least common denominator mode with heterogeneity between equipment.
Characterization, Kinetics, and Crystal Structures of Fructose-1,6-bisphosphate Aldolase from the Human Parasite, Giardia lamblia (2006)

Class I and class II fructose-1,6-bisphosphate aldolases (FBPA), glycolytic pathway enzymes, exhibit no amino acid sequence homology and utilize two different catalytic mechanisms. The mammalian class I FBPA employs a Schiff base mechanism, whereas the human parasitic protozoan Giardia lamblia class II FBPA is a zinc-dependent enzyme. In this study, we have explored the potential exploitation of the Giardia FBPA as a drug target. First, synthesis of FBPA was demonstrated in Giardia trophozoites by using an antibody-based fluorescence assay. Second, inhibition of FBPA gene transcription in Giardia trophozoites suggested that the enzyme is necessary for the survival of the organism under optimal laboratory growth conditions. Third, two crystal structures of FBPA in complex with the transition state analog phosphoglycolohydroxamate (PGH) show that the enzyme is homodimeric and that its active site contains a zinc ion. In one crystal form, each subunit contains PGH, which is coordinated to the zinc ion through the hydroxamic acid hydroxyl and carbonyl oxygen atoms. The second crystal form contains PGH only in one subunit and the active site of the second subunit is unoccupied. Inspection of the two states of the enzyme revealed that it undergoes a conformational transition upon ligand binding. The enzyme cleaves d-fructose-1,6-bisphosphate but not d-tagatose-1,6-bisphosphate, which is a tight binding competitive inhibitor. The essential role of the active site residue Asp-83 in catalysis was demonstrated by amino acid replacement. Determinants of catalysis and substrate recognition, derived from comparison of the G. lamblia FBPA structure with Escherichia coli FBPA and with a closely related enzyme, E. coli tagatose-1,6-bisphosphate aldolase (TBPA), are described.
Standard linear CMOS image sensor insensitive to temperature variations (2010)

CMOS vision sensors, as all electronic systems, are very sensitive to temperature variation. Mainly, this sensitivity limits their DC electrical behaviour. So far, no elegant integrated solution of this shortcoming has been proposed. In this paper, we introduce a compensation technique within the circuit in order to decrease power consumption and response time. To overcome this defect caused by temperature, we propose a temperature compensation method based on drain current I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DS</sub> characteristics with temperature. Among these characteristics we have a Zero Temperature Coefficient (ZTC) which will be used to compensate temperature variation. With this method, we reduce 98% of the influence of temperature on the output value of a standard CMOS image sensor, and obtain good temperature stability (1 mV) in the temperature ranges from -30°C to 125°C. The proposed temperature compensation method is described in details in this paper. Finally, we present simulations results, along with advantages and disadvantages of our compensation method.
Fully Integrated Biopotential Acquisition Analog Front-End IC (2015)

A biopotential acquisition analog front-end (AFE) integrated circuit (IC) is presented. The biopotential AFE includes a capacitively coupled chopper instrumentation amplifier (CCIA) to achieve low input referred noise (IRN) and to block unwanted DC potential signals. A DC servo loop (DSL) is designed to minimize the offset voltage in the chopper amplifier and low frequency respiration artifacts. An AC coupled ripple rejection loop (RRL) is employed to reduce ripple due to chopper stabilization. A capacitive impedance boosting loop (CIBL) is designed to enhance the input impedance and common mode rejection ratio (CMRR) without additional power consumption, even under an external electrode mismatch. The AFE IC consists of two-stage CCIA that include three compensation loops (DSL, RRL, and CIBL) at each CCIA stage. The biopotential AFE is fabricated using a 0.18 μm one polysilicon and six metal layers (1P6M) complementary metal oxide semiconductor (CMOS) process. The core chip size of the AFE without input/output (I/O) pads is 10.5 mm². A fourth-order band-pass filter (BPF) with a pass-band in the band-width from 1 Hz to 100 Hz was integrated to attenuate unwanted signal and noise. The overall gain and band-width are reconfigurable by using programmable capacitors. The IRN is measured to be 0.94 μVRMS in the pass band. The maximum amplifying gain of the pass-band was measured as 71.9 dB. The CIBL enhances the CMRR from 57.9 dB to 67 dB at 60 Hz under electrode mismatch conditions.
Glioblastoma and intracranial aneurysms: Case report and review of literature (2015)

Several theories stand to explain the coincidental occurrence of intracranial aneurysms and GBM. The treating physician should be aware of this association when patients with intraaxial tumors present with unusual manifestation such as an intratumoral hemorrhage or angiogram negative subarachnoid hemorrhage. No guidelines exist to assist in the management of such patients; therefore, authors have attempted to address this issue using a classification and treatment algorithm.
Maxwellian near-eye display with an expanded eyebox (2020)

Maxwellian view systems can be employed to circumvent the vergence-accommodation conflict in near-eye displays (NEDs), which directly project images onto the retina regardless of the human eye's depth of focus. However, Maxwellian view optics typically have a limited eyebox, which prevents broader applications of this architecture in NEDs. Here, we demonstrate a thin-film two-dimensional beam deflector composed of multi-twist broad-band Pancharatnam-Berry deflectors to mitigate this limitation via eyebox replication. Based on experimental validation, our proposed design can display always-focused full-color images within a 9 mm × 9 mm eyebox and thus mitigate the limitation of conventional Maxwellian displays while adding negligible weight and volume.
Laboratory methods for determining the effects of bactericides on acid mine drainage (1984)

Chemolithotrophic bacteria, particularly Thiobacillus ferrooxidans, can accelerate the oxidation of iron sulfide minerals. Materials toxic to these bacteria can be used to control acid mine drainage. For practical application, it is necessary to evaluate bactericides by determining the concentration at which they are effective for the spoil or refuse on which they are to be used. Two laboratory methods have been developed. In the batch method, ten-gram aliquots of ground refuse powder treated with water or bactericide solutions were incubated in centrifuge bottles for specified periods of time in a humidity chamber. Analyses were done by extracting the samples into a measured volume of water and assaying. In the column leach method, glass columns were used containing one-kilogram samples of refuse of controlled particle size distribution to ensure uniform flow characteristics in all columns. A system for metering water or bactericide solutions into the columns at pre-determined rates was used. Column effluents were assayed weekly. In both methods, comparisons with controls were used to determine the effects of bactericide treatments. Test protocol, versatility and limitations are described using sodium lauryl sulfate as the bactericide.
Specific Interaction of Cytokinins and Their Analogs with Rotenone-sensitive Internal NADH Dehydrogenase in Potato Tuber Mitochondria (1997)

Effects of cytokinins were studied on rotenone-sensitive NADH dehydrogenase in mitochondria from fresh potato tubers (Solanum tuberosum), in consideration of the operation of external and rotenone-insensitive internal NADH dehydrogenases that has not been fully accounted for in previous studies. In submitochondrial particles (smp), zeatin was only weakly active, and zeatin riboside (ZR) was inactive. Inhibition rates at 400 microns of isopentenyladenine (iP) and isopentenyladenosine (iPA) were 45% and 30%, respectively, and that of BA (BA) was 64%. In intact mitochondria, the inhibition by iP and BA significantly increased, I50 being 50 and 250 microM, respectively, but that by zeatin and iPA decreased. A structure-activity study showed that hydrophobic and steric factors are important for the activity. Cytokinins inhibited the electron flow via natural quinone more strongly than that via synthetic quinone. These results suggest that among the cytokinins the species that can regulate the electron transport is iP rather than its riboside or zeatin.
Induction System for a Proton Bunch Acceleration in Synchrotron (2006)

Recently the first induction acceleration of a single proton bunch of 2.3E10ppp was demonstrated [1], where it was accelerated from 500MeV to 8GeV in 1.9sec in KEK-PS. This paper describes the induction system for a synchrotron and a beam confinement experiment as a second step of the proof-of principle (PoP) experiments of a “induction synchrotron” [2], where a proton beam with a bunch length of 500ns was longitudinally confined by the induction barriers for 500msec, is introduced..
Isolation and Structure of Ascochlorin and Its Analogs (1974)

Ascochlorin and its analogs were isolated from the filter cake of the fermented broth of a fungus, Ascochyta viciae Libert; the compounds obtained were ascochlorin, LL–Z1272 δ, LL–Z1272 ε, ascofuranone, ascofuranol and a new analog, C23H31ClO5. Some of these prenyl phenols show hypolipidemic activity in both normolipidemic and hyperlipidemic rats. Details of the structure determination for ascochlorin are presented. The structure of the new analog was elucidated as 4′-hydroxy-5′-hydroascochIorin.
A wireless sensor network compatible wearable u-healthcare monitoring system using integrated ECG, accelerometer and SpO<sub>2</sub> (2008)

This paper presents the design and development of a wearable ubiquitous healthcare monitoring system using integrated electrocardiogram (ECG), accelerometer and oxygen saturation (SpO(2)) sensors. In this design, non-intrusive healthcare system was designed based on wireless sensor network (WSN) for wide area coverage with minimum battery power to support RF transmission. We have developed various devices such as wearable ubiquitous sensor network (USN) node, wearable chest sensor belt and wrist pulse oximeter for this system. Low power ECG, accelerometer and SpO(2) sensors board was integrated to the wearable USN node for user's health monitoring. The wearable ubiquitous healthcare monitoring system allows physiological data to be transmitted in wireless sensor network using IEEE 802.15.4 from on-body wearable sensor devices to a base-station which is connected to a server PC. Physiological data can be displayed and stored in the server PC continuously.
The effect of photoisomerization on the enzymatic hydrolysis of polymeric micelles bearing photo-responsive azobenzene groups at their cores (2016)

The design of stable polymeric micelles that can respond to specific stimuli is crucial for the development of smart micellar nanocarriers that can release their active cargo selectively at the target site, thus diminishing the therapeutic limitations due to non-selective damage to healthy tissues. Here we report the design and synthesis of photo- and enzyme-responsive amphiphilic PEG-dendron hybrids bearing one, two or four enzymatically cleavable azobenzene end-groups. These dual-responsive hybrids can respond to light through the reversible isomerization of the azobenzene end-groups from the non-polar trans isomer to the highly polar cis isomer and vice versa, upon UV and visible irradiation, respectively. The high structural precision of these hybrids, which emerges from the dendritic architecture, enabled a detailed study of the photoisomerization of the azobenzene end-groups with high molecular resolution. Remarkably, although the transition from trans-to-cis led to a significant increase in the polarity of the micellar cores, the micelles remained stable. Our kinetic studies show that although the trans isomer is a better substrate for the activating enzyme, the UV induced formation of the cis azobenzene end-groups led to significant acceleration of the enzymatic hydrolysis of the end-groups. These results provide strong indication that the enzyme cannot reach the core of the micelles and instead the end-groups have to leave the hydrophobic core in order to be exposed on the micelle's surface or even leave the micelle in order to allow their cleavage by the activating enzymes.
Flexible and fast IP lookup algorithm (2002)

We introduce a fast IP table lookup algorithm that improves the table updating time as well as the IP address searching time. Because routers with Patricia trie can not support giga-bit performance, many algorithms to support giga-bit routing performance by reducing the searching time have been introduced. Most of them, however, did not considerably count the importance of the updating time. As a network often falls into unstable states, a router may generate and receive hundreds of update request messages per second. So the router should be able to update its routing table at least 1000 times per second to appropriately run in real networks. We consider the updating time as much an important factor as the searching time in proposing a flexible and fast IP lookup algorithm (FFILA). Our scheme searches the table about 3 times faster than Patricia trie. It also shows improved performance in updating time by at least 30% when compared with Patricia trie. Also as many backbone routers today have over 100,000 routing table entries and its number is still increasing due to the growth in the network size, the memory requirement for the lookup algorithm becomes more important. An additional advantage of our algorithm is in its small memory requirement, which is good to overcome the scalability problem.
Microemulsions in Technical Processes (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMicroemulsions in Technical ProcessesMilan-Johann Schwuger, Katrin Stickdorn, and Reinhard SchomaeckerCite this: Chem. Rev. 1995, 95, 4, 849–864Publication Date (Print):June 1, 1995Publication History Published online1 May 2002Published inissue 1 June 1995https://pubs.acs.org/doi/10.1021/cr00036a003https://doi.org/10.1021/cr00036a003research-articleACS PublicationsRequest reuse permissionsArticle Views2745Altmetric-Citations373LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts