gebhart/patrepeval huggingface dataset:
Prediction of the cutting forces in gear hobbing and the wear behavior of the individual hob cutting teeth (2018)

In this paper, a mathematical model is presented, by which the cutting forces in a gear hobbing process and the wear behaviour of the hob's all cutting teeth are predicted. The load on each individual hob cutting tooth varies heavily in the gear hobbing process. To predict the cutting force, and subsequently the tool wear, a detailed determination of the chip geometry is needed. The undeformed chip geometry is continuously determined by analytical differential description presented in previous research. In the model all cut chips are determined for the full production cycle of a gear blank, where the gear blank boundaries are considered. Considering the full production cycle is needed to get an understanding of the load the tool will experience and the wear behaviour of the hob teeth. [Submitted 17 January 2017; Accepted 24 November 2017]
Molecular cloning of two Arabidopsis UDP-galactose transporters by complementation of a deficient Chinese hamster ovary cell line (2004)

Nucleotide-sugar transporters (NSTs) form a family of structurally related transmembrane proteins that transport nucleotide-sugars from the cytoplasm to the endoplasmic reticulum and Golgi lumen. In these organelles, activated sugars are substrates for various glycosyltransferases involved in oligo- and polysaccharide biosynthesis. The Arabidopsis thaliana genome contains more than 40 members of this transporter gene family, of which only a few are functionally characterized. In this study, two Arabidopsis UDP-galactose transporter cDNAs (UDP-GalT1 and UDP-GalT2) are isolated by expression cloning using a Chinese hamster ovary cell line (CHO-Lec8) deficient in UDP-galactose transport. The isolated genes show only 21% identity to each other and very limited sequence identity with human and yeast UDP-galactose transporters and other NSTs. Despite this low overall identity, the two proteins clearly belong to the same gene family. Besides complementing Lec8 cells, the two NSTs are shown to transport exclusively UDP-galactose by an in vitro NST assay. The most homologous proteins with known function are plant transporters that locate in the inner chloroplast membrane and transport triose-phosphate, phosphoenolpyruvate, glucose-6-phosphate, and xylulose 5-phosphate. Also, the latter proteins are members of the same family, which therefore has been named the NST/triose-phosphate transporter family.
Reduction of errors in vibratory gyroscopes by double modulation (1964)

Vibratory drive, vibratory output instruments for sensing angular rates, such as tuning forks, potentially offer certain advantages over conventional gyroscopes. The theoretical performance of these devices has not been realized experimentally because of zero-rate errors attributed to mass unbalance, driving force unbalance and other imperfections. By separating the driving and sensing frequencies through a process called double modulation, obtained through an additional rotation or vibration of the basic sensing element, zero-rate errors may be diminished. Theoretical and experimental evidence in support of the double modulation concept is presented. A tuning-fork type of instrument has been used in the initial experiments and a substantial improvement over the performance of the same instrument without double modulation has been realized.
Discovery of functional and approximate functional dependencies in relational databases (2003)

This study develops the foundation for a simple, yet efficient method for uncovering functional and approximate functional dependencies in relational databases. The technique is based upon the mathematical theory of partitions defined over a relation's row identifiers. Using a levelwise algorithm the minimal non-trivial functional dependencies can be found using computations conducted on integers. Therefore, the required operations on partitions are both simple and fast. Additionally, the row identifiers provide the added advantage of nominally identifying the exceptions to approximate functional dependencies, which can be used effectively in practical data mining applications.
Notes on the theory of modulation (1963)

The transmission system of "frequency modulation" (transmission by variation of the frequency of the radiated wave) is mathematically analyzed, and the width of the band of frequencies occupied by this method of transmission at a given speed is compared with the width of the corresponding band for transmission by amplitude variation. It is proved that the frequency modulation system using a spacing or compensating wave is inferior to the amplitude variation system both as to the width of the frequency band occupied and as to distortion of signal waveform.
Trisomy 13 is strongly associated with AML1/RUNX1 mutations and increased FLT3 expression in acute myeloid leukemia (2007)

AML1/RUNX1 is implicated in leukemogenesis on the basis of the AML1-ETO fusion transcript as well as somatic mutations in its DNA-binding domain. Somatic mutations in RUNX1 are preferentially detected in acute myeloid leukemia (AML) M0, myeloid malignancies with acquired trisomy 21, and certain myelodysplastic syndrome (MDS) cases. By correlating the presence of RUNX1 mutations with cytogenetic and molecular aberration in a large cohort of AML M0 (N = 90) at diagnosis, we detected RUNX1 mutations in 46% of cases, with all trisomy 13 cases (n = 18) being affected. No mutations of NRAS or KIT were detected in the RUNX1-mutated group and FLT3 mutations were equally distributed between RUNX1-mutated and unmutated samples. Likewise, a high incidence of RUNX1 mutations (80%) was detected in cases with trisomy 13 from other French-American-British (FAB) subgroups (n = 20). As FLT3 is localized on chromosome 13, we hypothesized that RUNX1 mutations might cooperate with trisomy 13 in leukemogenesis by increasing FLT3 transcript levels. Quantitation of FLT3 transcript levels revealed a highly significant (P < .001) about 5-fold increase in AML with RUNX1 mutations and trisomy 13 compared with samples without trisomy 13. The results of the present study indicate that in the absence of FLT3 mutations, FLT3 overexpression might be a mechanism for FLT3 activation, which cooperates with RUNX1 mutations in leukemogenesis.
Generating Correlated Digital Certificates: Framework and Applications (2016)

Bolstering public key authentication of networking entities, digital certificates are an entrenched part of Internet security. A digital certificate is an electronic document signed by a certificate authority (CA), vouching that the identified subject owns the declared public key (and the corresponding private key). In general, CAs are also responsible for certificate revocation as well as reissue, and certificates by nature are considered independent of each other. In this paper, we address the problem of certificate management and propose a flexible framework to create correlated certificates. We then apply it to implement the so-called multi-certificate public key infrastructure, which supports user self services, such as certificates' spontaneous substitution as well as self-reissue after self-revocation. To the best of our knowledge, this is the first scheme for certificate users to achieve self-reissue. Another application of the proposed framework is the so-called anonymous digital certificate, which still binds a user's identity to her public key, but in an anonymous yet user-controllable manner. That is, a user can reveal her identity-key binding only to her specified communication peers, while remaining anonymous to the general public, achieving privacy as these certificates are generally unlinkable.
The Alignment API 4.0 (2011)

Alignments represent correspondences between entities of two ontologies. They are produced from the ontologies by ontology matchers. In order for matchers to exchange alignments and for applications to manipulate matchers and alignments, a minimal ag
Epoxy-Amino Groups:  A New Tool for Improved Immobilization of Proteins by the Epoxy Method (2003)

The properties of a new commercially available amino-epoxy support (amino-epoxy-Sepabeads) for immobilizing enzymes have been compared to those of conventional epoxy supports. The new support has a layer of epoxy groups over a layer of ethylenediamine that is covalently bound to the support. Thus, this support has a great anionic exchanger power and a high number of epoxy groups. We have found a number of advantages to this new heterofunctional support. Immobilization proceeds at low ionic strength using amino epoxy Sepabeads while requiring high ionic strength using conventional monofunctional epoxy supports. Immobilization is much more rapid using amino-epoxy supports than employing conventional epoxy supports. The possibility of achieving immobilized preparations in which the enzyme orientation may be different to that obtained using the traditional hydrophobic supports (with likely effects in terms of activity or stability). Stability of the immobilized enzyme has been found to be much higher using the new support than in preparations using the conventional ones in many cases. Here we show some examples of these advantages using different enzymes (beta-galactosidases, lipase, glutaryl acylase, invertase, and glucoamylase).
Neutrophil and Pathogen Proteinases versus Proteinase-Activated Receptor-2 Lung Epithelial Cells (2006)

The proteinase-activated receptor-2 (PAR-2) is expressed by different lung cells, including bronchial and alveolar epithelial cells. Since its discovery in 1995, numerous in vivo and in vitro studies have demonstrated its involvement in lung inflammation, whether from infectious or allergic causes. However, its role is controversial because there is evidence of both pro- and anti-inflammatory activities. PARs, including PAR-2, display a unique activation process. Specific proteinases cleave the N-terminal extracellular domain at a particular site. The new N-terminal sequence functions as a tethered ligand and binds intramolecularly to activate the receptor. Recently, other specific proteinases have been shown to cleave the N-terminal exodomain at other sites, resulting in a disarming of the receptor. Some of these activating and disabling proteinases are produced by host cells and others by pathogens, and may be present in the airspaces under diverse pathophysiologic settings.
Assessment of performance of fringing electric field sensor arrays (2003)

Model-based multi-wavelength interdigital dielectrometry parameter estimation algorithms require a good agreement between theory and measurements. Research data indicate that the agreement is high for measurement of the properties of fluid dielectrics or the sensor substrate. However, the non-ideality of the surface contact between the sensor and solid materials creates significant differences between the idealized model and experimental results. One solution to this problem is to evaluate surface contact conditions for every measurement and account for them in software. Two alternative sensor designs are compared in this paper in their ability to provide reliable measurement data that can be used by parameter estimation algorithms. Measurement of dielectric and conduction properties of both fluids and solid dielectrics are considered. It is shown that the distribution of the electric field excitation over the entire multi-wavelength sensor head, as opposed to using separate electrode wavelengths, leads to reduction of errors in parameter estimation.
Ionothermal Synthesis of Crystalline, Condensed, Graphitic Carbon Nitride (2008)

Herein we report the synthesis of a crystalline graphitic carbon nitride, or g-C(3)N(4), obtained from the temperature-induced condensation of dicyandiamide (NH(2)C(=NH)NHCN) by using a salt melt of lithium chloride and potassium chloride as the solvent. The proposed crystal structure of this g-C(3)N(4) species is based on sheets of hexagonally arranged s-heptazine (C(6)N(7)) units that are held together by covalent bonds between C and N atoms which are stacked in a graphitic, staggered fashion, as corroborated by powder X-ray diffractometry and high-resolution transmission electron microscopy.
A Modified Pure Tone Audiometry Technique for Medico-Legal Assessment (2000)

A modified method of pure tone audiometry (PTA) in which the auditory threshold is approached from silence in ascending steps, with tone presentations of 1-4 seconds and interval durations of 1.5-5 seconds was assessed against the British Society of Audiology (BSA) method of PTA in terms of its ability to establish valid thresholds in cases of non-organic hearing loss, prevalent in medico-legal testing. The results reveal that the modified technique of PTA is a valid threshold measurement for honest subjects, and yields less non-organic overlay than the standard method of PTA in cases of non-organic hearing loss.
Secure distributed routing in ad hoc networks (2004)

In mobile ad hoc networks, nodes do not rely on any routing infrastructure but the nodes route messages for each other. This communication set up functions properly only when the participating nodes cooperate with each other in routing and forwarding. It may, however, be advantageous for some nodes not to cooperate (e.g, to save power or get more bandwidth or to launch security attacks). This paper describes a security solution for an ad hoc network routing protocol in the context of associativity based routing (ABR) protocol.
Clinical and histological study of permanent alopecia after bone marrow transplantation (2015)

The first pattern corroborates the literature cases of permanent alopecia induced by chemotherapeutic agents, and the second is compatible with manifestation of chronic graft-versus-host disease on scalp, that has never been described yet. The results contribute to the elucidation of the factors involved in these cases, including the development of therapeutic methods.
Automatic installation of software-based fault tolerance algorithms in programs generated by GCC compiler (2010)

The problem of designing radiation-tolerant devices working in application critical systems becomes very important especially if human life depends on the reliability of control mechanisms. One of the possible solution of this problem are pure software protection methods. They constitute different category of techniques to detect transient faults and correct corresponding errors. Software fault tolerance schemes are cheaper to implement since they can be used with standard, commercial of-the-shelf (COTS) components. Additionally, they do not require any hardware modification. In this paper, author propose a new implementation mechanism for software based fault protection algorithms performed automatically during application compilation.
Diabetes Mellitus and Cardiovascular Disease in Women (1998)

Diabetes appears to obviate the protective effects of female sex hormones. Possible reasons for this catastrophic effect of diabetes in women are discussed.
An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells (2010)

Transcription factors, such as Oct4, are critical for establishing and maintaining pluripotent cell identity. Whereas the genomic locations of several pluripotency transcription factors have been reported, the spectrum of their interaction partners is underexplored. Here, we use an improved affinity protocol to purify Oct4-interacting proteins from mouse embryonic stem cells (ESCs). Subsequent purification of Oct4 partners Sall4, Tcfcp2l1, Dax1, and Esrrb resulted in an Oct4 interactome of 166 proteins, including transcription factors and chromatin-modifying complexes with documented roles in self-renewal, but also many factors not previously associated with the ESC network. We find that Esrrb associated with the basal transcription machinery and also detect interactions between transcription factors and components of the TGF-beta, Notch, and Wnt signaling pathways. Acute depletion of Oct4 reduced binding of Tcfcp2l1, Dax1, and Esrrb to several target genes. In conclusion, our purification protocol allowed us to bring greater definition to the circuitry controlling pluripotent cell identity.
<i>publCIF</i>: software for editing, validating and formatting crystallographic information files (2010)

publCIF is an application designed for creating, editing and validating crystallographic information files (CIFs) that are used in journal publication. It validates syntax and dictionary-defined data attributes through internal routines, and also provides a web interface to the checkCIF service of the International Union of Crystallography (IUCr), which provides a full crystallographic analysis of the structural data. The graphical interface allows users to edit the CIF either in its `raw' ASCII form (using a text editor with context-sensitive data validation and input facilities) or as a formatted representation of a structure report (using a word-processing environment), as well as via a number of convenience tools ( e.g. spreadsheet representations of looped data). Beyond file and data validation, publCIF provides access to resources to facilitate preparation of a structure report ( e.g. databases of author details, experimental data, standard references etc ., either distributed with the program or collected during its use), along with tools for reference parsing, spell checking, structure visualization and image management. publCIF was commissioned by the IUCr, both as free software for authors and as a tool for in-house journal production; the tool for authors is described here. Binary distributions for Linux, MacOS and Windows operating systems are available.
The PPP and the Market Agenda (2009)

Productivity Places Program (PPP) is a national partnership that was endorsed for the VET sector at COAG meeting, 2008. The flagship of the Federal Government's election commitments in VET, the Productivity Places Program (PPP) continues to be used by the government to leverage greater competition over price across the VET sector, for the PPP must be delivered contestably.
Una nueva relación laboral especial de los empleados públicos (2007)

El estudio trata sobre la nueva relacion laboral especial para los empleados publicos, con la que cuestiona dicha naturaleza y, a la vez, fija su regimen juridico en su dimension individual: nacimiento, extincion, clasificacion profesional, retribucion, etc., asi como en su dimension colectiva: negociacion, conflictos y reunion. Hay un tratamiento especial de la contratacion temporal. Una reflexiva valoracion critica cierra tan completo como claro analisis.
LIBTP: Portable, Modular Transactions for UNIX (1992)

Transactions provide a useful programming paradigm for maintaining logical consistency, arbitrating concurrent access, and managing recovery. In traditional UNIX systems, the only easy way of using transactions is to purchase a database system. Such systems are often slow, costly, and may not provide the exact functionality desired. This paper presents the design, implementation, and performance of LIBTP, a simple, non-proprietary transaction library using the 4.4BSD database access routines (db(3)). On a conventional transaction processing style benchmark, its performance is approximately 85% that of the database access routines without transaction protection, 200% that of using fsync(2) to commit modifications to disk, and 125% that of a commercial relational database system. 1. Introduction Transactions are used in database systems to enable concurrent users to apply multi-operation updates without violating the integrity of the database. They provide the properties of atomicity, ...
Exceptional points in optics and photonics (2019)

Exceptional points are branch point singularities in the parameter space of a system at which two or more eigenvalues, and their corresponding eigenvectors, coalesce and become degenerate. Such peculiar degeneracies are distinct features of non-Hermitian systems, which do not obey conservation laws because they exchange energy with the surrounding environment. Non-Hermiticity has been of great interest in recent years, particularly in connection with the quantum mechanical notion of parity-time symmetry, after the realization that Hamiltonians satisfying this special symmetry can exhibit entirely real spectra. These concepts have become of particular interest in photonics because optical gain and loss can be integrated and controlled with high resolution in nanoscale structures, realizing an ideal playground for non-Hermitian physics, parity-time symmetry, and exceptional points. As we control dissipation and amplification in a nanophotonic system, the emergence of exceptional point singularities dramatically alters their overall response, leading to a range of exotic optical functionalities associated with abrupt phase transitions in the eigenvalue spectrum. These concepts enable ultrasensitive measurements, superior manipulation of the modal content of multimode lasers, and adiabatic control of topological energy transfer for mode and polarization conversion. Non-Hermitian degeneracies have also been exploited in exotic laser systems, new nonlinear optics schemes, and exotic scattering features in open systems. Here we review the opportunities offered by exceptional point physics in photonics, discuss recent developments in theoretical and experimental research based on photonic exceptional points, and examine future opportunities in this area from basic science to applied technology.
A first linkage map and downy mildew resistance QTL discovery for sweet basil (Ocimum basilicum) facilitated by double digestion restriction site associated DNA sequencing (ddRADseq) (2017)

Limited understanding of sweet basil (Ocimum basilicum L.) genetics and genome structure has reduced efficiency of breeding strategies. This is evidenced by the rapid, worldwide dissemination of basil downy mildew (Peronospora belbahrii) in the absence of resistant cultivars. In an effort to improve available genetic resources, expressed sequence tag simple sequence repeat (EST-SSR) and single nucleotide polymorphism (SNP) markers were developed and used to genotype the MRI x SB22 F2 mapping population, which segregates for response to downy mildew. SNP markers were generated from genomic sequences derived from double digestion restriction site associated DNA sequencing (ddRADseq). Disomic segregation was observed in both SNP and EST-SSR markers providing evidence of an O. basilicum allotetraploid genome structure and allowing for subsequent analysis of the mapping population as a diploid intercross. A dense linkage map was constructed using 42 EST-SSR and 1,847 SNP markers spanning 3,030.9 cM. Multiple quantitative trait loci (QTL) model (MQM) analysis identified three QTL that explained 37-55% of phenotypic variance associated with downy mildew response across three environments. A single major QTL, dm11.1 explained 21-28% of phenotypic variance and demonstrated dominant gene action. Two minor QTL dm9.1 and dm14.1 explained 5-16% and 4-18% of phenotypic variance, respectively. Evidence is provided for an additive effect between the two minor QTL and the major QTL dm11.1 increasing downy mildew susceptibility. Results indicate that ddRADseq-facilitated SNP and SSR marker genotyping is an effective approach for mapping the sweet basil genome.