gebhart/patrepeval huggingface dataset:
Neural Network Encapsulation (2018)

A capsule is a collection of neurons which represents different variants of a pattern in the network. The routing scheme ensures only certain capsules which resemble lower counterparts in the higher layer should be activated. However, the computational complexity becomes a bottleneck for scaling up to larger networks, as lower capsules need to correspond to each and every higher capsule. To resolve this limitation, we approximate the routing process with two branches: a master branch which collects primary information from its direct contact in the lower layer and an aide branch that replenishes master based on pattern variants encoded in other lower capsules. Compared with previous iterative and unsupervised routing scheme, these two branches are communicated in a fast, supervised and one-time pass fashion. The complexity and runtime of the model are therefore decreased by a large margin. Motivated by the routing to make higher capsule have agreement with lower capsule, we extend the mechanism as a compensation for the rapid loss of information in nearby layers. We devise a feedback agreement unit to send back higher capsules as feedback. It could be regarded as an additional regularization to the network. The feedback agreement is achieved by comparing the optimal transport divergence between two distributions (lower and higher capsules). Such an add-on witnesses a unanimous gain in both capsule and vanilla networks. Our proposed EncapNet performs favorably better against previous state-of-the-arts on CIFAR10/100, SVHN and a subset of ImageNet.
AUTOMATIC DESIGN OF BROADBAND GRADIENT INDEX METAMATERIAL LENS FOR GAIN ENHANCEMENT OF CIRCULARLY POLARIZED ANTENNAS (2013)

A broadband gradient index (GRIN) metamaterial lens for gain enhancement of circularly polarized antennas has been automatically designed, fabricated and investigated. The GRIN metamaterial lens consists of an isotropic dielectric plate with a corresponding distribution of deep-subwavelength drill holes each with the same diameter. Such drill holes have a negligible influence on both the polarization state and the spectral response of the electromagnetic wave transmitting through the resulting GRIN metamaterial lens. Therefore, the GRIN metamaterial lens is polarization-insensitive and can efficiently transform spherical waves into planar waves over a very broad frequency range keeping the initial polarization states (e.g., linear or circular) scarcely changed. In the following we have derived analytical formulas that enable the setup of distribution rules
Alkaline denaturation of bovine serum albumin. II. Analysis by isoelectric focusing in polyacrylamide gels. (1987)

Bovine serum albumins exposed to pH 11.9 for various periods (5min.-6hr.) at 20°C were analyzed by isoelectric focusing in polyacrylamide gels. Native BSA** monomers gave, in the electrofocusing pattern, three peaks with pI values 4.84, 5.15, and 5.39. After exposure to alkali, apparent shifts in the isoelectric point of some of the peaks and the appearance of new peaks with pI values 5.48, 5. 52, 5.70, 5.85, and 5.91 were observed.Components of these peaks are broadly divisible into the following three fractions: 1. The“first fraction”which consists of the main components of native BSA monomer (pI≤5.15). 2. The “second fraction”composed of SS-interchanged isomers (5.15<pI>5.70). 3. The“third fraction” consisting of irreversibly unfolded products (pI≥5.70). The alkaline denaturation can be expressed by the following reaction diagram: the“first fraction”→the“second fraction”→the“third fraction”.When the solution of native BSA monomer is exposed to pH 11.9 at 20°C for 4hr., new components 1, 1″, 1′, 2, and 3 are formed (the“second reaction”). Each of these components was isolated in the pure state by preparative disc gel electrophoresis and analyzed by electrofocusing. The results obtained are as follows: The component 1 and the native BSA monomer are composed of only the “first and second fractions”, but differ from each other in the situation of ionizable groups. Components 1″, 1′, 2, and 3 each consists of all the three“fractions”. The components 2 and 3 are similar and 1″and 1 also resemble each other, both in the state of charged groups. It is postulated that in the“second reaction”fatty acids, the impurity bound to BSA, migrate from the component 1″ to the component 1 in the course of the reaction, 1→1″.
High Density 3D Pre-Stack Q Estimation (2004)

P004 HIGH DENSITY 3D PRE-STACK Q ESTIMATION Summary 1 EAGE 66th Conference & Exhibition — Paris France 7 - 10 June 2004 S. J. LANCASTER & M. C. TANIS BP Exploration EPTG Chertsey Road Sunbury-upon-Thames Middlesex TW16 7LN England For optimum resolution after pre-stack depth migration amplitude phase and bandwidth distortions need to be corrected first. Here we describe a novel approach to estimating an offset space and time varying Q field in 3D based on monochromatic spectral decay. The method is demonstrated on data from the Southern Caspian Basin where gas accumulations in the overburden above the Shah Deniz
Characterization of Specific Humoral Immunity in Asymptomatic SARS-CoV-2 Infection (2021)

Abstract The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in December 2019 caused a huge blow to both global public health and global economy. At the early stage of the coronavirus disease 2019 (COVID-19) epidemic, asymptomatic individuals with SARS-CoV-2 infection were ignored, without appropriate identification and isolation. However, asymptomatic individuals proved to comprise a high proportion of all SARS-CoV-2-infected individuals, which greatly contributed to the rapid and wide spread of this disease. In this review, we summarize the latest advances in epidemiological characteristics, diagnostic assessment methods, factors related to the establishment of SARS-CoV-2 asymptomatic infection, as well as humoral immune features after SARS-CoV-2 infection or vaccination in asymptomatic individuals, which would contribute to effective control of ongoing COVID-19 epidemic.
Proline metabolism in N2-fixing root nodules: energy transfer and regulation of purine synthesis. (1988)

N2-fixing root nodules of soybean (Glycine max L. Merr.) convert atmospheric N2 to ammonia(um) in an energy-intensive enzymatic reaction. These nodules synthesize large quantities of purines because nitrogen fixed by bacteria contained within this tissue is transferred to the shoots in the form of ureides, which are degradation products of purines. In animal systems, it has been proposed that proline biosynthesis by pyrroline-5-carboxylate reductase (P5CR) is used to generate the NADP+ required for the synthesis of the purine precursor ribose 5-phosphate. We have examined the levels, properties, and location of P5CR and proline dehydrogenase (ProDH) in soybean nodules. Nodule P5CR was found in the plant cytosol. Its activity was substantially higher than that reported for other animal and plant tissues and is 4-fold higher than in pea (Pisum sativum) nodules (which export amides). The Km for NADPH was lower by a factor of 25 than the Km for NADH, while the Vmax with NADPH was one-third of that with NADH. P5CR activity was diminished by NADP+ but not by proline. These characteristics are consistent with a role for P5CR in supporting nodule purine biosynthesis rather than in producing proline for incorporation into protein. ProDH activity was divided between the bacteroids and plant cytosol, but less than 2% was in the mitochondria-rich fractions. The specific activity of ProDH in soybean nodule bacteroids was comparable to that in rat liver mitochondria. In addition, we propose that some of the proline synthesized in the plant cytosol by P5CR is catabolized within the bacteroids by ProDH and that this represents a novel mechanism for transferring energy from the plant to its endosymbiont.
Potential importance of alterations in hydrogen sulphide (H<sub>2</sub>S) bioavailability in diabetes (2008)

Despite its long-standing reputation as a foul smelling and toxic gas that is associated with the decay of biological matter,hydrogen sulphide (H2S) has emerged as an important regulator of cardiovascular homoeostasis. H2S promotes a number of cellular signals that regulate metabolism, cardiac function and cell survival. Endogenous H2S bioavailability is regulated by several enzymes involved in the biosynthesis of cysteine. This study by Brancaleone et al. in the current issue of the British Journal of Pharmacology provides novel insights into the impairment of H2S biosynthesis in the setting of diabetes mellitus. The authors report that enzymic H2S biosynthesis is impaired in a murine model of type 1 diabetes and the attenuation in H2S bioavailability is associated with impaired vascular reactivity. This study has profound implications for the use of pharmacological agents to augment endogenous H2S synthesis or agents that release H2S to augment the levels of this gaseous signalling molecule in cardiovascular disease.
Test Cases Reduction and Selection Optimization in Testing Web Services (2012)

Software testing in web services environment faces different challenges in comparison with testing in traditional software environments. Regression testing activities are triggered based on software changes or evolutions. In web services, evolution is not a choice for service clients. They have always to use the current updated version of the software. In addition test execution or invocation is expensive in web services and hence providing algorithms to optimize test case generation and execution is vital. In this environment, we proposed several approach for test cases' selection in web services' regression testing. Testing in this new environment should evolve to be included part of the service contract. Service providers should provide data or usage sessions that can help service clients reduce testing expenses through optimizing the selected and executed test cases.
Germ Cell Transplantation in an Azoospermic Klinefelter Bull1 (2003)

Germ cell transplantation is a technique that transfers donor testicular cells into recipient testes. A population of germ cells can colonize the recipient testis, initiate spermatogenesis, and produce sperm capable of fertilization. In the present study, a nonmosaic Klinefelter bull was used as a germ cell recipient. The donor cell suspension was introduced into the rete testis using ultrasound-guided puncture. A pulsatile administration of GnRH was performed to stimulate spermatogenesis. The molecular approach to detect donor cells was done by a quantitative polymerase chain reaction with allele discrimination based on a genetic mutation between donor and recipient. Therefore, a known genetic mutation, associated with coat-color phenotype, was used to calculate the ratio of donor to recipient cells in the biopsy specimens and ejaculates for 10 mo. After slaughtering, meiotic preparations were performed. The injected germ cells did not undergo spermatogenesis. Six months after germ cell transplantation, the donor cells were rejected, which indicates that the donor cells could not incorporate in the testis. The hormone stimulation showed that the testosterone-producing Leydig cells were functionally intact. Despite subfertility therapy, neither the recipient nor the donor cells underwent spermatogenesis. Therefore, nonmosaic Klinefelter bulls are not suitable as germ cell recipients. Future germ cell recipients in cattle could be mosaic Klinefelters, interspecies hybrids, bulls with Sertoli cell-only syndrome, or bulls with disrupted germ cell migration caused by RNA interference.
2-MERCAPTOBENZIMIDAZOLE (1950)

The physical properties of 2-mercapto benzimidazole and main methods for its preparation are introduced.The situations of production and demand for 2-mercapto benzimidazole in China and in Japan are described in brief. Meanwhile,the application fields of 2-mercapto benzimidazole as rubber antioxidant and pharmacy intermediate are summarized.
Synthesis of Aza/Oxaspiro-γ-lactams by Radical Translocation Cyclization Reactions (2005)

A cascade radical translocation cyclization of the N-­allyl-N-(2′-bromophenyl)amide moiety of heterocyclic carboxylic acids and its N-propynyl analogues were investigated. It provides a convenient method for the preparation of aza/oxaspiro-γ-lactams that are useful γ-turn mimetics in drug discovery.
30 Gb/s all-optical clock recovery circuit (2000)

All-optical clock recovery is demonstrated from pseudo-data patterns at 30 Gb/s. The circuit is based on the optical gain modulation of a semiconductor optical amplifier fiber laser. The recovered clock is a 2.7-ps pulse train, with very low modulation pattern even in the presence of more than 200 consecutive 0's in the data signal.
Effect of stimulation rate on phoneme recognition by Nucleus-22 cochlear implant listeners (2000)

This study investigated the effect of pulsatile stimulation rate on medial vowel and consonant recognition in cochlear implant listeners. Experiment 1 measured phoneme recognition as a function of stimulation rate in six Nucleus-22 cochlear implant listeners using an experimental four-channel continuous interleaved sampler (CIS) speech processing strategy. Results showed that all stimulation rates from 150 to 500 pulses/s/electrode produced equally good performance, while stimulation rates lower than 150 pulses/s/electrode produced significantly poorer performance. Experiment 2 measured phoneme recognition by implant listeners and normal-hearing listeners as a function of the low-pass cutoff frequency for envelope information. Results from both acoustic and electric hearing showed no significant difference in performance for all cutoff frequencies higher than 20 Hz. Both vowel and consonant scores dropped significantly when the cutoff frequency was reduced from 20 Hz to 2 Hz. The results of these two experiments suggest that temporal envelope information can be conveyed by relatively low stimulation rates. The pattern of results for both electrical and acoustic hearing is consistent with a simple model of temporal integration with an equivalent rectangular duration (ERD) of the temporal integrator of about 7 ms.
Redox‐Active Organic Compounds for Future Sustainable Energy Storage System (2020)

Abstract Utilizing redox‐active organic compounds for future energy storage system (ESS) has attracted great attention owing to potential cost efficiency and environmental sustainability. Beyond enriching the pool of organic electrode materials with molecular tailoring, recent scientific efforts demonstrate the innovations in various cell chemistries and configurations. Herein, recent major strategies to build better organic batteries, are highlighted: diversifying charge‐carrying ions, modifying electrolytes, and utilizing liquid‐type organic electrodes. Each approach is summarized along with their advantages over Li‐ion batteries (LIBs). An outlook is also provided on the practical realization of organic battery systems, which hints at possible solutions for future sustainable ESSs.
Studies of lipase‐catalyzed esterification reactions of some acetylenic fatty acids (1998)

Esterification of five positional isomers of acetylenic fatty acids [viz. 9:1(2a), 11:1(10a), 18:1(6a), 18:1(9a) and 22:1(13a)] of different chain lengths with n-butanol in n-hexane in the presence of eight different lipases [Lipozyme IM 20 (Rhizomucor miehei), Lipolase 100T (R. miehei), Novozyme 435 (Candida antarctica), PPL (porcine pancreatic lipase), CCL (C. cylindracea), PS-D (Pseudomonas cepacia), Lipase A-12 (Aspergillus niger) and Lipase AY-30 (C. rugosa)] was studied. 2-Nonynoic acid was not esterified except when catalyzed by the lipase from C. antarctica (Novozyme 435) to give 42% butyl ester after 48 h. The lipases from A. niger (Lipase A-12) and C. rugosa (Lipase AY-30) showed poor biocatalytic behavior in the esterification of the acetylenic fatty acids studied. 10-Undecynoic acid gave the highest conversion rate of esterification with each kind of lipase used. 6-Octadecynoic acid showed a marked degree of resistance to esterification carried out in the presence of C. cylindracea (CCL), P. cepacia (PS-D), or porcine pancreatic (PPL) lipase but not significantly in the presence of the lipases of R. miehei (Lipozyme IM 20), R. miehei (Lipolase 100T), or Novozyme 435. 9-Octadecynoic acid and 13-docosynoic acid were not discriminated and were readily esterified by the remaining six lipases, but when compared to oleic acid the acetylenic fatty acids were comparatively much slower in conversion to the esters.
Rapid immune reconstitution after a reduced‐intensity conditioning regimen and a CD3‐depleted haploidentical stem cell graft for paediatric refractory haematological malignancies (2006)

The main obstacles to successful haploidentical haematopoietic stem cell transplantation from a mismatched family member donor are delayed immune reconstitution, vulnerability to infections and severe graft-versus-host disease (GvHD). We designed a reduced-intensity conditioning regimen that excluded total body irradiation and anti-thymocyte globulin in order to expedite immune reconstitution after a CD3-depleted haploidentical stem cell transplant. This protocol was used to treat 22 paediatric patients with refractory haematological malignancies. After transplantation, 91% of the patients achieved full donor chimaerism. They also showed rapid recovery of CD3(+) T-cells, T-cell receptor (TCR) excision circle counts, TCRbeta repertoire diversity and natural killer (NK)-cells during the first 4 months post-transplantation, compared with those results from a group of patients treated with a myeloablative conditioning regimen. The incidence and extent of viremia were limited and no lethal infection was seen. Only 9% of patients had grade 3 acute GvHD, while 27% patients had grade 1 and another 27% had grade 2 acute GvHD. This well-tolerated regimen appears to accelerate immune recovery and shorten the duration of early post-transplant immunodeficiency, thereby reducing susceptibility to viral infections. Rapid T-cell reconstitution, retention of NK-cells in the graft and induction of low grade GvHD may also enhance the potential anti-cancer immune effect.
The importance of p53-independent apoptosis in the intestinal toxicity induced by raltitrexed (ZD1694, Tomudex): genetic differences between BALB/c and DBA/2 mice. (2000)

The thymidylate synthase inhibitor raltitrexed (ZD1694, Tomudex) induces greater intestinal toxicity, manifested as diarrhea and weight loss, in BALB/c than in DBA/2 mice. No convincing pharmacokinetic or pharmacodynamic reason for this strain difference has been established. We have investigated whether this strain difference in response to raltitrexed is related to differential susceptibilities of intestinal mucosae to undergo apoptosis and also whether p53 expression, a critical factor in 5-fluorouracil-induced intestinal apoptosis and toxicity, modulates this response. Ten mg/kg or 100 mg/kg raltitrexed were administered as single or double i.p. injections 24 h apart to BALB/c, DBA/2, and p53-/- mice. Apoptosis, mitosis, and tissue damage were assessed in intestinal epithelium, and animal weight was recorded. BALB/c mice developed diarrhea and weight loss following 100 mg/kg x2 raltitrexed, whereas DBA/2 mice did not. BALB/c mice were more sensitive than DBA/2 to induction of small-intestinal and colonic apoptosis 24 h following 100 mg/kg raltitrexed. Inhibition of mitosis was equivalent in both strains. Both strains showed histopathological damage to the small intestine after 100 mg/kg x2 raltitrexed, but only BALB/c mice demonstrated colonic damage. p53-null mice showed the same level of small intestinal apoptosis as their wild-type counterparts 24 h after 100 mg/kg x1 raltitrexed and also the same levels of intestinal toxicity 3, 5, and 7 days after 100 mg/kg x2 raltitrexed. Thus, BALB/c mice were more susceptible to induction of intestinal apoptosis by raltitrexed than DBA/2 mice and also demonstrated more histopathological damage in the colon correlating with the induction of diarrhea and weight loss. In contrast to 5-fluorouracil, the intestinal apoptosis and toxicity induced by raltitrexed were p53-independent.
Spatial and intensity modulation of light emission from a silicon LED matrix (2002)

A novel experimental multiterminal silicon light emitting diode matrix is described, where both the emitted light intensity and the spatial light pattern of the device are controlled by insulated metal-oxide-semiconductor (MOS) gate voltages. It is found that the light intensity is a nonlinear quadratic function of the applied gate voltage. The nonlinear relationship enables, for example, the mixing of electrical input signals and modulation of the optical output signal, which can not readily be achieved with two terminal Si-light-emitting diodes, since they exhibit a linear relationship between diode avalanche current and light intensity.
Post-War Nutritional Relief (1944)

In Charlottenburg the rations, which covered almost all food except green vegetables, from 28th April to 1st June 1919, after relief supplies to Germany had begun, supplied only 1671 Calories per head a week, bacon to 2.6 02. and meat to 7 oz.
MR angiography of the cerebral perforating arteries with magnetization prepared anatomical reference at 7T: Comparison with time‐of‐flight (2008)

The benefits of ultra-high-field MRI can transform MPRAGE into a new angiography method to image small vessels and associated parenchyma at the same time. This technique can be used to study the correlation between tissue damage and vascular pathology.
Physical Modeling of the Capacitance and Capacitive Coupling Noise of Through-Oxide Vias in FDSOI-Based Ultra-High Density 3-D ICs (2012)

Fully depleted silicon-on-insulator (FDSOI) technology boosts the opportunity to make 3-D ICs with ultrahigh integration density, due to the short and tiny through-oxide vias (TOVs), which are made after removing the entire silicon under the buried-oxide layer. This work, for the first time, develops compact physical models for the capacitance of the TOV and the coupling capacitance between the TOV and active regions in the presence of periodical power/ground lines, from fundamental electrostatic considerations. Calculation results from the models show good agreement with the simulation results from a full-3-D capacitance solver. The models are further used to analyze the threshold voltage ( <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">V</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sub> ) variation in the FDSOI MOSFETs. The TOV in FDSOI and the through-silicon via (TSV) in bulk-CMOS-based 3-D ICs are finally compared in terms of the self-impedance as well as their impact on MOSFET <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">V</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sub> variation through capacitive noise coupling. These results provide important insights to TOV/TSV design and optimization in emerging 3-D ICs.