gebhart/patrepeval huggingface dataset:
Bifunctional Molecular Sieve Catalysts for the Benign Ammoximation of Cyclohexanone:  One-Step, Solvent-Free Production of Oxime and ε-Caprolactam with a Mixture of Air and Ammonia (2001)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTBifunctional Molecular Sieve Catalysts for the Benign Ammoximation of Cyclohexanone: One-Step, Solvent-Free Production of Oxime and ε-Caprolactam with a Mixture of Air and AmmoniaRobert Raja, Gopinathan Sankar, and John Meurig ThomasView Author Information Davy Faraday Research Laboratory The Royal Institution of Great Britain 21 Albemarle Street, London, U.K. W1S 4BS Department of Chemistry, University of Cambridge Lensfield Road, Cambridge, U.K. CB2 1EW Department of Materials Science and Metallurgy University of Cambridge, U.K. CB2 3QZ Cite this: J. Am. Chem. Soc. 2001, 123, 33, 8153–8154Publication Date (Web):July 31, 2001Publication History Received20 April 2001Revised30 May 2001Published online31 July 2001Published inissue 1 August 2001https://doi.org/10.1021/ja011001+Copyright © 2001 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views1708Altmetric-Citations93LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (89 KB) Get e-AlertsSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Catalysts,Ions,Mixtures,Redox reactions,Transition metals Get e-Alerts
Natural products of Thailand high Δ<sup>1</sup>-THC-strain Cannabis. The bibenzyl-spiran-dihydrophenanthrene group: relations with cannabinoids and canniflavones (1982)

Since non-cannabinoids may influence the pharmacological profile of Cannabis-leaf drug, a detailed examination of the acidic fraction from leaf extractive has been made. Twelve non-cannabinoids have been isolated crystalline from a single high Δ1-THC-strain of Thailand Cannabis grown in Nottingham under controlled conditions: nine of the compounds were not previously known as natural products and their structures have been determined. The extractives comprise three bibenzyls, six spirans, two 9,10-dihydrophenanthrenes, and two prenylated flavones.The bibenzyls, spirans, and dihydrophenanthrenes may be linked together in a biogenetic scheme in which one-electron oxidation and reductive processes play important parts: the scheme is particularly supported by the discovery of a new spiran, cannabispiradienone, which holds a key position and undergoes a dienone–phenol rearrangement to give one of the new dihydrophenanthrenes. Relations between bibenzyl, cannabinoid, and flavone pathways are briefly considered.
Amoxycillin in the control of furunculosis in Atlantic salmon parr (1992)

The efficacy of amoxycillin in the control of laboratory induced Aeromonas salmonicida infection in Atlantic salmon parr was investigated. When given in the diet at a dose rate of 80 mg per kg bodyweight it was effective against both a moderate and severe challenge (with mortality rates in untreated groups of 75 per cent and 45 per cent). At 40 mg per kg it was effective against the moderate challenge only. The plasma levels in these regimens were 1.25 micrograms per ml and 0.3 to 0.6 micrograms per ml and the minimum inhibitory concentration of the challenge strain of A salmonicida was 0.6 micrograms per ml. The potential of the Charm radiobioassay system in detecting antibiotic residues in fish tissue was studied. The level of amoxycillin in muscle and bone from fish in mid-treatment at 80 mg per kg was 0.32 micrograms per ml. After a 12 day withdrawal period at 18 degrees C no residue was detected within the 0.005 micrograms per ml limit of this test.
Atypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural Analysis (2013)

The immunoglobulin new antigen receptors (IgNARs) are a class of Ig-like molecules of the shark immune system that exist as heavy chain-only homodimers and bind antigens by their single domain variable regions (V-NARs). Following shark immunization and/or in vitro selection, V-NARs can be generated as soluble, stable, and specific high affinity monomeric binding proteins of ∼12 kDa. We have previously isolated a V-NAR from an immunized spiny dogfish shark, named E06, that binds specifically and with high affinity to human, mouse, and rat serum albumins. Humanization of E06 was carried out by converting over 60% of non-complementarity-determining region residues to those of a human germ line Vκ1 sequence, DPK9. The resulting huE06 molecules have largely retained the specificity and affinity of antigen binding of the parental V-NAR. Crystal structures of the shark E06 and its humanized variant (huE06 v1.1) in complex with human serum albumin (HSA) were determined at 3- and 2.3-Å resolution, respectively. The huE06 v1.1 molecule retained all but one amino acid residues involved in the binding site for HSA. Structural analysis of these V-NARs has revealed an unusual variable domain-antigen interaction. E06 interacts with HSA in an atypical mode that utilizes extensive framework contacts in addition to complementarity-determining regions that has not been seen previously in V-NARs. On the basis of the structure, the roles of various elements of the molecule are described with respect to antigen binding and V-NAR stability. This information broadens the general understanding of antigen recognition and provides a framework for further design and humanization of shark IgNARs.
Two-Dimensional Simulation of Tunneling Using Quantum Lattice-Gas Automata (2005)

We present two-dimensional (2D) simulation of quantum tunneling across the potential barrier with surface roughness. The impact of the 2D simulation on the transmission coefficient is investigated by comparing the results with 1D simulations. It is also shown that the transmission coefficient depends on the parallel momentum of the incident particle due to the scattering by the surface roughness.
Feature-based respiratory motion tracking in native fluoroscopic sequences for dynamic roadmaps during minimally invasive procedures in the thorax and abdomen (2017)

Fluoroscopic image guidance for minimally invasive procedures in the thorax and abdomen suffers from respiratory and cardiac motion, which can cause severe subtraction artifacts and inaccurate image guidance. This work proposes novel techniques for respiratory motion tracking in native fluoroscopic images as well as a model based estimation of vessel deformation. This would allow compensation for respiratory motion during the procedure and therefore simplify the workflow for minimally invasive procedures such as liver embolization. The method first establishes dynamic motion models for both the contrast-enhanced vasculature and curvilinear background features based on a native (non-contrast) and a contrast-enhanced image sequence acquired prior to device manipulation, under free breathing conditions. The model of vascular motion is generated by applying the diffeomorphic demons algorithm to an automatic segmentation of the subtraction sequence. The model of curvilinear background features is based on feature tracking in the native sequence. The two models establish the relationship between the respiratory state, which is inferred from curvilinear background features, and the vascular morphology during that same respiratory state. During subsequent fluoroscopy, curvilinear feature detection is applied to determine the appropriate vessel mask to display. The result is a dynamic motioncompensated vessel mask superimposed on the fluoroscopic image. Quantitative evaluation of the proposed methods was performed using a digital 4D CT-phantom (XCAT), which provides realistic human anatomy including sophisticated respiratory and cardiac motion models. Four groups of datasets were generated, where different parameters (cycle length, maximum diaphragm motion and maximum chest expansion) were modified within each image sequence. Each group contains 4 datasets consisting of the initial native and contrast enhanced sequences as well as a sequence, where the respiratory motion is tracked. The respiratory motion tracking error was between 1.00 % and 1.09 %. The estimated dynamic vessel masks yielded a Sørensen-Dice coefficient between 0.94 and 0.96. Finally, the accuracy of the vessel contours was measured in terms of the 99th percentile of the error, which ranged between 0.64 and 0.96 mm. The presented results show that the approach is feasible for respiratory motion tracking and compensation and could therefore considerably improve the workflow of minimally invasive procedures in the thorax and abdomen
Multi-objective genetic algorithm based on selection (2010)

The use of genetic algorithm to multi-objective optimization problems, whose solutions are uniformly distributed in the objective space. Sometimes the user only wants to get more solutions in the particular region of the objective space. A selectionbased multi-objective genetic algorithm was proposed to solve the problems. It directed optimization in the genetic operating based on the user’s selection, and made the satisfactory solutions was found.
Experimental Comparison of Angle and Space Diversity for Line-of-Sight Microwave Links (1985)

In line-of-sight (LOS) links which use space or frequency diversity to combat multipath fading, the fading in each diversity branch is uncorrelated provided the antenna spacing or frequency separation is sufficiently large. Therefore, the availability or outage probability of space and frequency diversity systems is closely described by independent (uncorrelated) Rayleigh fading statistics. In the case of angle diversity, uncorrelated Rayleigh fading does not describe the performance of the angle diversity system. In fact, the fading on the two branches is positively correlated when the fades are shallow and negatively correlated when the fades are deep; i.e., if a deep fade occurs in one branch there is a high probability that the signal in the other diversity branch will not fade. In this paper we discuss briefly the theory of angle diversity and present the results of a short experimental program to compare the performance of angle diversity and space diversity on a fading LOS microwave link.
Sequence motifs required for lipid droplet association and protein stability are unique to the hepatitis C virus core protein (2000)

From analysis of the primary sequence of the hepatitis C virus (HCV) core protein, we have identified three separable regions based on hydrophobicity and clustering of basic amino acids within the protein. Comparison with capsid proteins of related pesti- and flaviviruses suggested that HCV core has a unique central domain (domain 2). Previous findings have revealed that core protein can associate with lipid droplets which are intracellular storage sites for triacylglycerols and cholesterol esters. Confocal analysis of variant forms lacking regions of core indicated that most residues within the unique region are necessary for association of the protein with lipid droplets. A segment within domain 2 (from residues 125 to 144) also was required for stability of the protein and a polypeptide lacking these sequences was degraded apparently by the proteasome. In cells depleted of lipid droplets, core protein remained located in the cytoplasm. Moreover, cleavage of the protein at the maturation site and stability were not affected by inability to bind to lipid droplets.
Interleukin-35: Expanding Its Job Profile (2015)

Counter-regulation afforded by specialized regulatory cell populations and immunosuppressive cytokines is critical for balancing immune outcome. The inhibitory potential of the established suppressive cytokines, IL-10 and TGFβ, has been well elucidated in diverse inflammatory scenarios in conjunction with their key roles in Treg development and function. Despite the early predictions for an immunomodulatory role for the Ebi3/p35 heterodimer in placental trophoblasts, IL-35 biology remained elusive until 2007 when it was established as a Treg-restricted inhibitory cytokine. Since then, Treg-derived IL-35 has been shown to exhibit its suppressive activities in a range of autoimmune diseases and cancer models. Recent studies are beginning to explore other cellular sources of IL-35, such as Bregs and CD8(+) Tregs. Despite these new cellular sources and targets, the mode of IL-35 suppression remains restricted to inhibition of proliferation and induction of an IL-35-producing induced regulatory T cell population referred to as iTr35. In this review, we explore the early beginnings, status quo, and future prospects of IL-35 biology. The unparalleled opportunity of targeting multiple immunosuppressive populations (Tregs, Bregs, CD8(+) Tregs) through IL-35 is highly exciting and offers tremendous promise from a translational standpoint, particularly for cancer immunotherapies.
Germline PTEN mutations in Cowden syndrome-like families. (1998)

Cowden syndrome (CS) or multiple hamartoma syndrome (MIM 158350) is an autosomal dominant disorder with an increased risk for breast and thyroid carcinoma. The diagnosis of CS, as operationally defined by the International Cowden Consortium, is made when a patient, or family, has a combination of pathognomonic major and/or minor criteria. The CS gene has recently been identified as PTEN, which maps at 10q23.3 and encodes a dual specificity phosphatase. PTEN appears to function as a tumour suppressor in CS, with between 13-80% of CS families harbouring germline nonsense, missense, and frameshift mutations predicted to disrupt normal PTEN function. To date, only a small number of tumour suppressor genes, including BRCA1, BRCA2, and p53, have been associated with familial breast or breast/ovarian cancer families. Given the involvement of PTEN in CS, we postulated that PTEN was a likely candidate to play a role in families with a "CS-like" phenotype, but not classical CS. To answer these questions, we gathered a series of patients from families who had features reminiscent of CS but did not meet the Consortium Criteria. Using a combination of denaturing gradient gel electrophoresis (DGGE), temporal temperature gel electrophoresis (TTGE), and sequence analysis, we screened 64 unrelated CS-like subjects for germline mutations in PTEN. A single male with follicular thyroid carcinoma from one of these 64 (2%) CS-like families harboured a germline point mutation, c.209T-->C. This mutation occurred at the last nucleotide of exon 3 and within a region homologous to the cytoskeletal proteins tensin and auxilin. We conclude that germline PTEN mutations play a relatively minor role in CS-like families. In addition, our data would suggest that, for the most part, the strict International Cowden Consortium operational diagnostic criteria for CS are quite robust and should remain in place.
Embedding Read-Only Memory in Spin-Transfer Torque MRAM-Based On-Chip Caches (2015)

We propose a design technique for embedding read-only memory (ROM) in spin-transfer torque MRAM (STT-MRAM) arrays by adding an extra bit-line in every column of the array. RAM and ROM data, which can be different, are stored in the same bitcell and the ROM capacity may be as large as the RAM capacity. Furthermore, our proposed ROM-embedding technique is applicable to any resistive memory technology in which the bit-cell topology is identical to that of the STT-MRAM bit-cell. An additional sense amplifier is required in the peripheral circuitry, hence we propose an area-optimized peripheral circuitry to minimize the total area penalty of embedding ROM. Our analysis reveals that the ROM may be embedded in the STT-MRAM array without area overhead and without any penalty in the performance of the memory as RAM. Furthermore, our simulations show that the embedded ROM may be used to accelerate applications that use lookup tables with as much as 30% improvement in instructions per cycle of a processor using ROM-embedded STT-MRAM for its L2 cache.
Analysis and Comparison of Modular Railway Power Conditioner for High-Speed Railway Traction System (2016)

With the rapid development of modern electrified railway, negative-sequence current minimization is one of the most important considerations in the high-speed railway traction system. In the past, many multiple or multilevel topologies with high compensation capacity have been introduced for railway power conditioner (RPC). This paper presents a simplified quantitative comparison of five previous modular RPC topologies for negative sequence compensation in V/V and SCOTT traction systems, aiming for an optimal selection of the compensators. Performance criteria such as transformer requirement, voltage stress and current stress of a power switch, numbers of the power switches and capacitor are derived by analytical methods. Moreover, the numerical comparison of operating controllers is completed for modular RPCs. In addition, power losses of five modular RPCs are obtained by theoretical analysis, IPOSIM calculation as well as PSIM simulation. These calculations are validated via simulations results in PSIM. The main conclusion is that presented modular RPCs can be divided into general purpose RPC and special purpose RPC in terms of the behavior and efficiency. It is helpful to choose the appropriate topology for specific applications.
Black and White Adult Family Members' Attitudes Toward a Dementia Diagnosis (2009)

Black and white adults with a family member who has received an diagnosis of AD perceive a range of benefits and few barriers to the diagnostic process examined in this study. Their positive experiences might be instructive to families considering pursuing a diagnosis and to physicians who may be reluctant to offer screening or referral because of the belief that families have little to gain.
Natural antioxidants in grapes and wines (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNatural antioxidants in grapes and winesJoseph Kanner, Edwin Frankel, Rina Granit, Bruce German, and John E. KinsellaCite this: J. Agric. Food Chem. 1994, 42, 1, 64–69Publication Date (Print):January 1, 1994Publication History Published online1 May 2002Published inissue 1 January 1994https://doi.org/10.1021/jf00037a010Request reuse permissionsArticle Views1816Altmetric-Citations342LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (722 KB) Get e-Alertsclose Get e-Alerts
Gastrointestinal symptoms under opioid therapy: A prospective comparison of oral sustained‐release hydromorphone, transdermal fentanyl, and transdermal buprenorphine (2008)

Gastrointestinal symptoms of cancer pain patients undergoing an opioid therapy are related to multifactorial causes. Transdermal opioids showed no benefit over oral controlled-release hydromorphone with regard to gastrointestinal symptoms. The conversion ratios for transdermal fentanyl, transdermal buprenorphine, and oral hydromorphone did not accord to the literature, because of differing occurrences of opioid tolerance after long-term therapy.
Spectroscopic studies on matrix isolated tungsten chlorides and bromides (1989)

Tungsten pentachloride has been heated in high vacuum, and the vapour species isolated in inert matrices at ca. 12 K. Subsequent i.r. spectra showed intense features at 410 and 365 cm–1 which are assigned as the A2″ and E′ stretching modes respectively of monomeric D3h WCl5. Corresponding studies on the hexachloride showed that monomeric WCl6 could similarly be isolated, and for this species, the u.v.–visible spectrum was also obtained and analysed in detail. The vaporisation of tungsten bromide samples of typical stoicheiometry WBr5.3 yielded a new spectroscopic feature in the matrix i.r. spectrum at ca. 305 cm–1 which is assigned to molecular WBr6. At higher temperatures, the vaporisation of the solid pentabromide resulted in bands at 280 and 245 cm–1 which are assigned as the A2″ and E′ stretching modes in D3h WBr5.
Cooperative Thermodynamic Control of Selectivity in the Self-Assembly of Rare Earth Metal–Ligand Helices (2013)

Metal-selective self-assembly with rare-earth cations is possible with suitable rigid, symmetrical bis-tridentate ligands. Kinetically controlled formation is initially observed, with smaller cations preferentially incorporated. Over time, the more thermodynamically favorable complexes with larger metals are formed. This thermodynamic control is a cooperative supramolecular phenomenon and only occurs upon multiple-metal-based self-assembly: single-metal ML3 analogues do not show reversible selectivity. The selectivity is dependent on small variations in lanthanide ionic radius and occurs despite identical coordination-ligand coordination geometries and minor size differences in the rare-earth metals.
All Men Are Brothers. By Mahatma Gandhi. New York: Columbia University Press, UNESCO, 1958. xvi, 196. Glossary, Sources, Selected Bibliography. $4.75. (1960)

Book Review| May 01 1960 All Men Are Brothers All Men Are Brothers. By Mahatma Gandhi. New York: Columbia University Press, UNESCO, 1958. xvi, 196. Glossary, Sources, Selected Bibliography. $4.75. Paul F. Power Paul F. Power St. Michael's College, Winooski, Vt. Search for other works by this author on: This Site Google Journal of Asian Studies (1960) 19 (3): 368–369. https://doi.org/10.2307/2943528 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Permissions Cite Icon Cite Search Site Citation Paul F. Power; All Men Are Brothers. Journal of Asian Studies 1 May 1960; 19 (3): 368–369. doi: https://doi.org/10.2307/2943528 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search Books & JournalsAll JournalsJournal of Asian Studies Search Advanced Search The text of this article is only available as a PDF. Copyright © The Association for Asian Studies, Inc. 19601960 Article PDF first page preview Close Modal You do not currently have access to this content.
Sexually transmitted diseases hamper development efforts. (1998)

This document examines the incidences and consequences of sexually transmitted diseases in developing countries and describes the importance of an intensified US commitment to the prevention and treatment of these diseases.