gebhart/patrepeval huggingface dataset:
Two-stage Sorption and Desorption of Organic Vapors in Cellulose Acetate<sup>1,2</sup> (1955)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTwo-stage Sorption and Desorption of Organic Vapors in Cellulose Acetate1,2E. Bagley and F. A. LongCite this: J. Am. Chem. Soc. 1955, 77, 8, 2172–2178Publication Date (Print):April 1, 1955Publication History Published online1 May 2002Published inissue 1 April 1955https://pubs.acs.org/doi/10.1021/ja01613a038https://doi.org/10.1021/ja01613a038research-articleACS PublicationsRequest reuse permissionsArticle Views363Altmetric-Citations159LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Regulation of human eosinophil precursor production by cytokines: a comparison of recombinant human interleukin-1 (rhIL-1), rhIL-3, rhIL-5, rhIL-6, and rh granulocyte-macrophage colony-stimulating factor (1990)

The effect of a panel of recombinant human (rh) cytokines on the generation of human eosinophil precursors was assessed using a two-step culture technique. Normal human bone marrow was preincubated with different cytokine combinations in liquid culture before assessment of the number of eosinophil progenitors, which give rise to eosinophil colony-forming units (CFU-Eo) on secondary semi-solid culture with either interleukin-5 (IL-5), IL-3, or granulocyte-macrophage colony- stimulating factor. rhIL-3 or rhGM-CSF, but not rhIL-5, increased the number of CFU-Eo. CFU-Eo production by rhIL-3 or rhGMCSF was maximal after 7 days' preincubation. Neither rhIL-1 or rhIL-6 acted on eosinophil precursors, either alone or in combination with rhIL-5, rhIL- 3, or rhGM-CSF. A similar spectrum of activity of the cytokines was demonstrated whether rhIL-5, rhIL-3, or rhGM-CSF was used in the secondary cultures as the eosinophil CSF. However, rhIL-3 induced relatively more rhIL-5-responsive CFU-Eo than rhIL-3-responsive CFU-Eo, suggesting that rhIL-3 is pushing progenitors into an rhIL-5-responsive compartment.
Advances in biologic augmentation for rotator cuff repair (2016)

Rotator cuff tear is a very common shoulder injury that often necessitates surgical intervention for repair. Despite advances in surgical techniques for rotator cuff repair, there is a high incidence of failure after surgery because of poor healing capacity attributed to many factors. The complexity of tendon-to-bone integration inherently presents a challenge for repair because of a large biomechanical mismatch between the tendon and bone and insufficient regeneration of native tissue, leading to the formation of fibrovascular scar tissue. Therefore, various biological augmentation approaches have been investigated to improve rotator cuff repair healing. This review highlights recent advances in three fundamental approaches for biological augmentation for functional and integrative tendon-bone repair. First, the exploration, application, and delivery of growth factors to improve regeneration of native tissue are discussed. Second, applications of stem cell and other cell-based therapies to replenish damaged tissue for better healing are covered. Finally, this review will highlight the development and applications of compatible biomaterials to both better recapitulate the tendon-bone interface and improve delivery of biological factors for enhanced integrative repair.
Cooperative interactions between paired domain and homeodomain (1996)

The Pax proteins are a family of transcriptional regulators involved in many developmental processes in all higher eukaryotes. They are characterized by the presence of a paired domain (PD), a bipartite DNA binding domain composed of two helix-turn-helix (HTH) motifs,the PAI and RED domains. The PD is also often associated with a homeodomain (HD) which is itself able to form homo- and hetero-dimers on DNA. Many of these proteins therefore contain three HTH motifs each able to recognize DNA. However, all PDs recognize highly related DNA sequences, and most HDs also recognize almost identical sites. We show here that different Pax proteins use multiple combinations of their HTHs to recognize several types of target sites. For instance, the Drosophila Paired protein can bind, in vitro, exclusively through its PAI domain, or through a dimer of its HD, or through cooperative interaction between PAI domain and HD. However, prd function in vivo requires the synergistic action of both the PAI domain and the HD. Pax proteins with only a PD appear to require both PAI and RED domains, while a Pax-6 isoform and a new Pax protein, Lune, may rely on the RED domain and HD. We propose a model by which Pax proteins recognize different target genes in vivo through various combinations of their DNA binding domains, thus expanding their recognition repertoire.
Orange Juice and Weather (1984)

Frozen concentrated orange juice is an unusual commodity. It is concentrated not only hydrologically, but also geographically; more than 98 percent of U.S. production takes place in the central Florida region around Orlando.' Weather is a major influence on orange juice production and un- like commodities such as corn and oats, which are produced over wide geographical areas, orange juice output is influenced primarily by the weather at a single location. This suggests that frozen concentrated orange juice is a relatively good candidate for a study of the interaction between prices and a truly exogenous determinant of value, the weather.
Spin-Spin Relaxation in La<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">F</mml:mi></mml:mrow><mml:mrow><mml:mn>3</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (1966)

The present work is a study by nmr pulse techniques of the motion of fluorine atoms in lanthanum trifluoride as a function of temperature, between 100 and 560\ifmmode^\circ\else\textdegree\fi{}C. The experiments have been conducted with a single crystal of La${\mathrm{F}}_{3}$. The model for the motions derived from this study is the following: There are two types of fluorine nuclei, the spins $I$ and the spins $S$, located on different sublattices. Between 100 and 300\ifmmode^\circ\else\textdegree\fi{}C, the motion of the spins $I$ is fast (i.e., such as to be appreciable in times shorter than the reciprocal of the rigid-lattice line width), and the motion of the spins $S$ is slow. There is an exchange of atoms between the two sublattices, the rate of which is slow up to about 300\ifmmode^\circ\else\textdegree\fi{}C and fast at higher temperature. The ratio of populations of the spins $I$ and $S$ is $\frac{{N}_{I}}{{N}_{S}}=2$. Approximate values are derived for the activiation energies associated with these two types of motion.
Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis (2002)

Hereditary hemochromatosis (HH) is a common genetic disorder characterized by excess absorption of dietary iron and progressive iron deposition in several tissues, particularly liver. The vast majority of individuals with HH are homozygous for mutations in the HFE gene. Recently a second transferrin receptor (TFR2) was discovered, and a previously uncharacterized type of hemochromatosis (HH type 3) was identified in humans carrying mutations in the TFR2 gene. To characterize the role for TFR2 in iron homeostasis, we generated mice in which a premature stop codon (Y245X) was introduced by targeted mutagenesis in the murine Tfr2 coding sequence. This mutation is orthologous to the Y250X mutation identified in some patients with HH type 3. The homozygous Tfr2(Y245X) mutant mice showed profound abnormalities in parameters of iron homeostasis. Even on a standard diet, hepatic iron concentration was several-fold higher in the homozygous Tfr2(Y245X) mutant mice than in wild-type littermates by 4 weeks of age. The iron deposition in the mutant mice was predominantly hepatocellular and periportal. The mean splenic iron concentration in the homozygous Tfr2(Y245X) mutant mice was significantly less than that observed in the wild-type mice. The homozygous Tfr2(Y245X) mutant mice also demonstrated elevated transferrin saturations. There were no significant differences in parameters of erythrocyte production including hemoglobin levels, hematocrits, erythrocyte indices, and reticulocyte counts. Heterozygous Tfr2(Y245X) mice did not differ in any measured parameter from wild-type mice. This study confirms the important role for TFR2 in iron homeostasis and provides a tool for investigating the excess iron absorption and abnormal iron distribution in iron-overload disorders.
Dermatitis in nude mice (<i>nu/nu</i>) associated with <i>Staphylococcus pyogenes</i> (1983)

Nude mice (nu/nu on BALB/cAn background), maintained under conventional conditions, developed an acute moist dermatitis of the nose and occasionally the ears, with heavy contamination with Staphylococcus pyogenes. Only homozygotes over 10 weeks old were affected. Treatment with parenteral ampicillin or oral oxytetracycline was ineffective. Other conditions associated with the same organism were conjunctivitis and periorbital abscesses.
How Water Meets a Hydrophobic Surface (2006)

Synchrotron x-ray reflectivity measurements of the interface between water and methyl-terminated octadecylsilane monolayers with stable contact angle >100 degrees conclusively show a depletion layer, whether or not the water is degassed. The thickness is of order one water molecule: 2-4 Angstrom with electron density <40% that of bulk water. Considerations of coherent and incoherent averaging of lateral inhomogeneities show that the data cannot be explained by "nanobubbles." When the contact angle is lower, unstable in time, or when monolayers fail to be sufficiently smooth over the footprint of the x-ray beam, there is no recognizable depletion.
[Local intravasal fibrinolysis in acute cerebrovascular occlusions]. (1989)

The development of local intravasal fibrinolysis in acute cerebrovascular obturations is lined out and the precautions, indications and contraindications as well as our results from 10 patients are described. The requirements of dosage, procedure and of a close cooperation and combination with further clinical treatment are given. Furthermore close cooperation with hemostaseology is stressed.
Soybean Cyst Nematode - Biology and Management (1999)

Soybean cyst nematode, Heterodera glycines, is a microscopic, unsegmented plant-parasitic roundworm that attacks the roots of soybeans.Many plant-parasitic nematodes are believed to be native to the United States, but soybean cyst nematode likely was introduced into the United States from Japan.Soybean cyst nematode was first discovered in the United States in 1954 in North Carolina (Winstead et al., 1955) and since has spread to 26 additional states in the Southeast and Midwest (Figure 1) (Noel, 1992).The nematode was first discovered in Iowa in Winnebago County in 1978.Currently, soybean cyst nematode is known to exist in 90 Iowa counties and is suspected to be present in many other counties as well.More than 70% of 400 randomly selected Iowa fields sampled in 1995 and 1996 were infested with the nematode (Workneh et al., 1998).
Bidirectional Replication of Simian Virus 40 DNA (1972)

SV40 (Simian Virus 40) DNA was pulse-labeled with [(3)H]thymidine in infected monkey cells, and the distribution of label within newly completed molecules was determined by analysis of specific fragments produced by restriction endonuclease from Hemophilus influenzae. From these data, an order of synthesis or temporal order of the fragments was deduced. Comparison of the temporal order with the physical order of the fragments in the SV40 DNA molecule indicates a correspondence in these orders for two separate groups of fragments. From an analysis of the results, we conclude that SV40 DNA replication begins at a specific site and proceeds bidirectionally, terminating about halfway around the circular molecule from the initiation point.
Synthesis and High Performance of Magnetofluorescent Polyelectrolyte Nanocomposites as MR/Near-Infrared Multimodal Cellular Imaging Nanoprobes (2011)

Here, we describe an easy but robust chemical strategy to synthesize high-performance magnetic resonance (MR)/near-infrared (NIR) multimodal imaging nanoprobes. Poly(γ-glutamic acid) was used for the convenient phase transfer of MnFe(2)O(4) nanoparticles dispersed in organic solvents into aqueous solutions and facilitated further ionic gelation with poly(l-lysine). During the gelation process, MnFe(2)O(4) nanoparticulate satellites were encapsulated in the ionic nanocomplex, which induced synergistic magnetism and resulted in huge T(2) relaxivity (r(2)). The positively charged outer surfaces were assembled with other negatively charged NIR emitting fluorescent nanocrystals and enabled the highly efficient delivery of the magnetofluorescent polyelectrolyte nanocomposites (MagFL-PEN) into cancer cells. The enhancement of negative contrast of MagFL-PEN at 2 μg/mL concentration was similar to that of Resovist at 20 μg/mL concentration. The NIR fluorescence microscopy images of the MagFL-PEN-labeled cells even at 12.5 pM were able to be clearly observed. The labeling efficiency of MagFL-PEN was approximately 65-fold higher compared to that of the commercialized fluorescent nanocrystals, only after 3 h incubation period, even at the test concentration (100 pM). Due to the high-performance capabilities both in materials properties and cell labeling efficiency, the MagFL-PEN is expected to be used as a highly efficient MR/NIR dual-modality imaging nanoprobe in the detection of cancer cells and monitoring of therapeutic cells in vivo.
Analysis of precision of the HTB packet scheduler (2005)

Network packet scheduling algorithms are used to provide QoS features. They are usually deployed in routers. Hierarchical Token Bucket packet scheduler is one of many offered packet scheduling algorithms in Linux kernel which is widely used as a combined firewall/router device. We have built a minimalistic Linux based distribution suited for firewalling and routing with QoS capabilities. In this paper we investigate the accuracy of such QoS router with the HTB packet scheduler when routing between LAN and typical WAN link of 1Mbit/s. Today's interactive protocols, like video and audio conferencing, voice over IP and virtual private networking require QoS to ensure that they are handled in a timely manner, reducing the chance of degraded quality.
Circuit-QED-based scalable architectures for quantum information processing with superconducting qubits (2015)

We discuss different ways of generating entanglement in the original picture of circuit QED (XcQED) and several restrictions that arise in the context of a large-scale quantum architecture. To alleviate some of the issues posed by the presence of the nonlinearities inherent to these systems, we introduce a layout for circuit QED, wherein an artificial atom is coupled to a quantized radiation field via its longitudinal degree of freedom (ZcQED). This system is akin to ion traps used in atomic physics, but it relies on fixed coupling between the atom and the resonator. We describe a scalable architecture for processing quantum information with superconducting qubits, which is free from any type of residual interaction between the atomic and photonic degrees of freedom. Tunable interactions can be realized based on sideband transitions, and the system can be operated out of the Lamb-Dicke regime, allowing it to benefit from the possibility of achieving large coupling strengths between atoms and resonators. We also discuss a readout scheme that does not require any extra circuits and allows a qubit-specific measurement of the state of the quantum register inspired by the electron shelving technique. This scheme is quantum nondemolition (QND)-like, and allows for single-shot determination of the qubit states.
Surgical treatment of cardiac arrhythmias. (1993)

Surgical treatment of cardiac arrhythmias will continue to evolve as advances in understanding of the mechanisms of these arrhythmias and technological developments in the areas of mapping and noninvasive diagnostic capabilities are made. As limitations with many aspects of pharmacological therapy become more apparent, surgical therapies will continue to play a pivotal role in the definitive treatment of these supraventricular and ventricular tachyarrhythmias.
Fully integrated optical system for lab-on-a-chip applications (2004)

We present a lab-on-a-chip device featuring a microfluidic dye laser, wave-guides, microfluidic components and photo-detectors integrated on the chip. The microsystem is designed for wavelength selective absorption measurements in the visible range on a fluidic sample, which can be prepared/mixed on-chip. The laser structures, wave-guides and micro-fluidic handling system are defined in a single UV-lithography step on a 10 /spl mu/m thick SU-8 layer on top of the substrate. The SU-8 structures are sealed by a Borofloat glass lid, using polymethylmethacrylate (PMMA) adhesive bonding.
Virulence, immunogenicity and reactivation of seven bovine herpesvirus 1.1 strains: clinical and virological aspects (1996)

Specific pathogen-free calves were inoculated intranasally with one of seven strains of bovine herpesvirus 1.1 (BHV 1.1) to identify a highly virulent strain for use in vaccination-challenge experiments. The calves were monitored clinically and virologically. Clear differences in virulence between the strains were observed. The Iowa strain was the most virulent; the four calves infected with the strain had the most severe clinical signs; two of them died and viraemia was detected in three of them. To evaluate the immunogenicity of the seven strains all the calves were challenged 16 weeks later with the Iowa strain. The calves of a control group showed the typical signs of a BHV1 infection, whereas all the other calves were protected against disease and shed little or no virus. Hence, the differences in virulence were not associated with differences in immunogenicity. After the calves had been treated with dexamethasone, differences were observed between the strains in the amount of virus that was excreted.
Thermal transition of native tobacco mosaic virus and RNA-free viral proteins into spherical nanoparticles (2010)

Spherical nanoparticles (SNPs) were generated by two-step thermal remodelling of native tobacco mosaic virus (TMV) at 94 °C. Particles of irregular shape and varying size were generated by TMV at 90 °C. They could be converted into SNPs by heating at 94 °C and were considered to be intermediate precursors of SNPs. In addition to SNP monomers (53 nm diameter), generated by individual TMV virions, large SNPs (100–800 nm diameter) were assembled. The size of the SNPs depended on the TMV concentration. The SNPs could be generated by distinct forms of RNA-free TMV coat protein (CP) aggregates and individual CP subunits. A one-step SNP assembly appeared to occur in these cases. These results show that SNPs represent a new type of particle nanoplatform for producing compositions of SNPs with foreign protein molecules bound to their surface.
A VLSI spike-driven dynamic synapse which learns only when necessary (2006)

We describe an analog VLSI circuit implementing spike-driven synaptic plasticity, embedded in a network of integrate-and-fire neurons. This biologically inspired synapse is highly effective in learning to classify complex stimuli in semi-supervised fashion. The circuits presented are designed in sub-threshold CMOS consuming extremely low power. The pulse-based neural network communicates with the outside world using the address event representation in an asynchronous fashion. We present measurements from a test chip, characterizing all the modules of the circuit and show how they match well with theoretical expectations. We finally demonstrate that the learning mechanism of the synapse is fully functional by stimulating it with Poisson distributed spike trains
Nurses’ Perceptions of Medication Errors in South India (2014)

Medication use in hospitals is a complex process and depends on successful interaction among health care professionals functioning at different areas. Errors may occur at any stage of prescribing, documenting, dispensing, preparation, or administration. This descriptive survey was conducted in the cardiac wing at a private tertiary care teaching hospital in Kerala, South India during January-February 2013 among 50 registered nurses with an aim to investigate what constitutes a medication error (ME), types of commonly observed errors, drugs involved, causes of error, reasons and existing barriers to reporting medication errors and characteristics of good and effecting ME reporting system among nurses working in a cardiac care center. Analysis revealed that the overall mean of medication errors they could remember making was 3.52, over the course of their career. Antibiotics, digoxin, warfarin/acitrom, dopamine/dobutamine were mostly involved in medication errors. The most common types of errors observed were drug administering without a physician order, omission error, followed by drug calculation error, Incorrect IV therapy timing/dosage/administered technique, and wrong time. Culture of blame within team members (15), Degree of harm occurred to the patient (15),patient aware of error(14), Sense of shame(13), Lack of familiarity/skills with how best to handle a situation (12), Error tolerance of institution(10), Rapport between patient and provider(6) influenced the decision to disclose a medication error. The most common barriers to reporting medication errors were, not getting any positive feedback for passing medications error (22) possible adverse consequences like loss of job/disciplinary action (21), not agreeing with hospital's definition of a medication error (16), feeling of incompetency from team members (15) and not recognizing occurred error (15). According to nurses the top 5 characteristics of a good and effective ME reporting system were the systems in which Medication orders are rewritten at transfer, Reasons for medication changes made at transfer are documented, non-punitive approach to reporting, Feedback of the results of the error analysis given those healthcare professionals involved, Home medications are brought in by patients. Despite a desire to deliver high quality care, errors occur on both a systems and personal level. Nurses have to take a front seat role in initiatives that have sought to address issues related to medication error, develop significant expertise in medication administration and associated systems to tackle issues of medication error.
Complex Sleep Apnea Syndrome: Is It a Unique Clinical Syndrome? (2006)

Patients with complex sleep apnea syndrome are mostly similar to those with OSAHS until one applies continuous positive airway pressure. They are left with very disrupted breathing and sleep on continuous positive airway pressure. Clinical risk factors don't predict the emergence of complex sleep apnea syndrome, and best treatment is not known.