gebhart/patrepeval huggingface dataset:
Montelukast Added to Inhaled Beclomethasone in Treatment of Asthma (1999)

The primary objective of this study was to determine whether montelukast, an oral leukotriene receptor antagonist, provides additional clinical benefit to the effect of inhaled corticosteroids. A total of 642 patients with chronic asthma (FEV(1) 50 to 85% of predicted value and at least a predefined level of asthma symptoms) incompletely controlled with inhaled beclomethasone, 200 microg twice daily using a spacer device, during the 4-wk run-in period were randomly allocated, in a double-blind, double-dummy manner to one of four treatment groups: (1) montelukast 10 mg plus continuing inhaled beclomethasone; (2) placebo tablet plus continuing inhaled beclomethasone; (3) montelukast 10 mg and inhaled placebo (after blind beclomethasone removal); and (4) placebo tablet and inhaled placebo (after blind beclomethasone removal). The primary endpoints were FEV(1) and daytime asthma symptoms score. Montelukast provided significant (p < 0.05) clinical benefit in addition to inhaled beclomethasone by improving FEV(1), daytime asthma symptom scores, and nocturnal awakenings. Blind removal of beclomethasone in the presence of placebo tablets caused worsening of asthma control, demonstrating that patients received clinical benefit from inhaled corticosteroids. Blind removal of beclomethasone in the presence of montelukast resulted in less asthma control but not to the level of the placebo group. All treatments were well tolerated; clinical and laboratory adverse experiences were generally similar to placebo treatment in this study. In conclusion, montelukast provided additional asthma control to patients benefitting from, but incompletely controlled on, inhaled beclomethasone.
Annual Reports on NMR Spectroscopy : Volume 78 (2013)

Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has gained such significance as NMR spectroscopy. It is used in all branches of science in which precise structural determination is required and in which the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a premier means for the specialist and non-specialist alike to become familiar with new techniques and applications of NMR spectroscopy.Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has gained such significance as NMR spectroscopy. It is used in all branches of science in which precise structural determination is required and in which the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a premier means for the specialist and non-specialist alike to become familiar with new techniques and applications of NMR spectroscopy.
Localization in wireless sensor network with mobile beacons (2004)

Sensor nodes in a wireless sensor network have limited power, low memory and little processing capability. One of the primary requirements of the localization algorithm is low power consumption. The paper presents an energy efficient localization algorithm for a wireless sensor network with moving beacons. It is different from other localization algorithms in the way sensors calculate their position. Four beacons move towards the node to be localized and form a square, the sensor node being at the center. The sensor node calculates its position as the centroid of the square after getting co-ordinate information from the four beacons at the corners of the square. Localized and non-localized nodes can be distinguished by assigning a unique code to each sensor in the network. The computational requirement at the node is very low and it has flexible accuracy.
Automatic migration velocity analysis and multiples (2008)

Migration velocity analysis attempts to find a velocity model by focusing a migration image with respect to a redundant coordinate, here a shift at depth between forward and time‐reversed wavefields. An automatic algorithm requires a wave propagation algorithm and an optimization scheme. A 2D frequency‐domain finite‐difference code for the two‐way wave equation provides the wavefields. A gradient‐based minimization scheme should find the velocity model best focuses the migration image. In the presence of multiples, the method may provide incorrect results because there is no mechanism to distinguish between primary and multiple reflections. Two modifications are proposed that may improve the result in the presence of multiples.
An adaptive framework for multimedia messaging services over wireless networks and the Internet (2004)

Messaging services have become a popular tool for communication over wireless networks and the Internet. With improvements in network bandwidth and growing user requirements, they have evolved into multimedia messaging services (MMS) that allow communication of multimedia data among users as well as service providers and their clients. The existing MMS framework standardized by the 3GPP and WAP Forum employs several components with the MMS proxy-relay (MPR) as a core element. The MPR provides messaging, browsing, content retrieval and storage services to clients by relaying messages and coordinating tasks with other components in the framework. This centralized function of routing messages and serving multimedia content on a first-come-first-served basis leads to inefficient load-balancing and traffic management across the framework. We propose an adaptive MMS framework and discuss the concept of caching proxies that utilize a priority-based scheme to better balance the payload, reduce congestion in network paths as well as minimize delays on future incoming requests to the MPR.
Surface nanopatterning of phosphorylcholine unit by well-defined block copolymer containing 2-methacryloyloxyethyl phosphorylcholine (2007)

Ordered surface patteming of biocompatible microdomain is potentially needed in many applications such as high sensitive biochips, biosensors, and nanobio devices for cell culturing. One of the efficient ways in the fabrication of patterned surface is using the microphase separation of well-defined block copolymers by controlling molecular weight and film formation process. Thus we synthesize several compositions of block copolymers containing 2-methacryloyloxyethyl phosphorylcholine (MPC) which is hydrophilic and shows excellent biocompatibility, and polydimethylsiloxane (PDMS) which has hydrophobic nature and usually used as soft lithography materials. All of the copolymers were synthesized by the atom transfer radical polymerization (A1RP) method at room temperature. The kinetics plot and molecular weight plot shows that the polymerizations of block copolymers were well controlled, thus the compositions of block copolymers were controllable. Two kinds of synthesized copolymers: the longest MPC segment and the shortest one, were cast on Si(IOO) substrate by spin casting or solvent casting. By using the IR-multichannel viewer and atom force microscope, we could conclude that the film formed by the longest MPC segment could not generate the well defmed surface structure due to its long chain aggregation. By using the copolymer containing the shortest MPC segment, we could generate a nanoscale ordered surface patterning of phorsphorylcholine unit
Synthesis of Highly Selective Magnetic Mesoporous Adsorbent (2009)

Magnetic MCM-41 of large surface area (ca. 800 m2 g−1) and high magnetization (ca. 8.3 emu g−1) was prepared at a reasonable iron oxide nanoparticles loading of 10 wt % by a two-step synthesis process. The 8 nm iron oxide nanoparticles (i.e., 30 m2 g−1) were embedded in the MCM-41 with no observable effects on the particle morphology and pore symmetry, but a slight change (i.e., <20%) in the textural properties and surface chemistry was detected. Aminopropyls (2.7 mmol g−1) were grafted on the mesopore channels followed by the adsorption of 1.2 mmol g−1 Fe3+ to prepare selective adsorbents for arsenic(V) and chromium(VI) oxyanions. Detailed analyses indicated that the surface modifications of the magnetic and nonmagnetic MCM-41 by aminopropyls and Fe3+ yield similar site chemistry and accessibility. The Fe3+-magMCM-41 and Fe3+-MCM-41 displayed comparable adsorption capacity and selectivity. Both adsorbed only As(V) and Cr(VI) oxyanions (i.e., 1.0 and 2.0 mmol g−1, respectively), and none of the Cu(II). The magnetic adsorbent was easily dispersed in aqueous solution and can be removed by a magnet (1550 G) at a rate of 1 cm min−1 compared to 0.004 cm min−1 by gravity.
Recent Advances on Phosphodiesterase 4 Inhibitors for the Treatment of Asthma and Chronic Obstructive Pulmonary Disease (2008)

ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTRecent Advances on Phosphodiesterase 4 Inhibitors for the Treatment of Asthma and Chronic Obstructive Pulmonary DiseaseArumugam Kodimuthali, S. Sugin Lal Jabaris, and Manojit Pal*View Author Information New Drug Discovery, R & D Center, Matrix Laboratories Limited, Anrich Industrial Estate, Bollaram, Jinnaram Mandal, Medak District, Andhra Pradesh, 502 325, India* To whom correspondence should be addressed. Telephone: 08458-279301. Fax: 08458-279305. E-mail: [email protected]Cite this: J. Med. Chem. 2008, 51, 18, 5471–5489Publication Date (Web):August 8, 2008Publication History Received17 May 2008Published online8 August 2008Published inissue 25 September 2008https://pubs.acs.org/doi/10.1021/jm800582jhttps://doi.org/10.1021/jm800582jreview-articleACS PublicationsCopyright © 2008 American Chemical SocietyRequest reuse permissionsArticle Views3325Altmetric-Citations145LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Inhibition,Inhibitors,Peptides and proteins,Reaction products,Rodent models Get e-Alerts
Joint Sensing, Communication, and Computation Resource Allocation for Cooperative Perception in Fog-Based Vehicular Networks (2021)

To enlarge the perception range and reliability of individual autonomous vehicles, cooperative perception has been received much attention. However, considering the high volume of shared messages, limited bandwidth and computation resources in vehicular networks become bottlenecks. In this paper, we investigate how to balance the volume of shared messages and constrained resources in fog-based vehicular networks. To this end, we first characterize sum satisfaction of cooperative perception taking account of its spatial-temporal value and latency performance. Next, the sensing block message, communication resource block, and computation resource are jointly allocated to maximize the sum satisfaction of cooperative perception, while satisfying the maximum latency and sojourn time constraints of vehicles. Owing to its non-convexity, we decouple the original problem into two separate sub-problems and devise corresponding solutions. Simulation results demonstrate that our proposed scheme can effectively boost the sum satisfaction of cooperative perception compared with existing baselines.
Chemotherapy of human tumor xenografts in genetically athymic mice. (1978)

A series of studies were undertaken to evaluate the chemotherapeutic response to various antineoplastic drugs of human breast (MX-1) or colon (CX-2) tumor xenografts growing in genetically athymic (nude) mice. Fragments (2mm3) of either tumor type were implanted subcutaneously into the subaxillary region of NIH Swiss nude mice, and single drug therapy was started when tumors became palpable and were growing progressively. 5-Fluorouracil (5-FU) administered on a Q7DX3 schedule starting on Day 21 post tumor implantation elicited significant retardation in the growth rate of CX-2 tumor. A single treatment with methyl-CCNU induced temporary tumor regression. Against MX-1 tumor, both cyclophosphamide and melphalan induced tumor regressions with no recurrence. 5-FU slowed but did not arrest growth of MX-1 tumor. These tumor systems grown in nude mice appear to be suitable models for in vivo screening of anticancer agents that would prove clinically active.
Type I Glanzmann's Thrombasthenia in a Great Pyrenees Dog (1996)

An 8-month-old female Great Pyrenees dog with chronic epistaxis and a history of gingival bleeding during shedding of deciduous teeth was evaluated for platelet function. Platelet morphology was normal at both the light and electron microscopic level. Platelet number and mean platelet volume were also normal. Platelet aggregation responses to adenosine diphosphate, collagen, platelet activating factor, and thrombin were markedly reduced, although shape change responses were normal. Clot retraction was markedly impaired. Monoclonal antibody (MoAb) Y2/51, a murine anti-human platelet beta 3 antibody that cross-reacts with canine platelet beta 3, and MoAb 5G11, a murine anti-dog platelet alpha IIb beta 3 antibody, bound minimally to affected dog platelets, as demonstrated by flow cytometry. Binding of MoAb Y2/51 was not detectable by immunoblot. MoAb CAP1, a murine anti-dog fibrinogen receptor-induced binding site antibody, failed to bind to affected dog platelets, as demonstrated by flow cytometry. A reduction in glycoproteins alpha IIb and beta 3 was demonstrated by two-dimensional protein electrophoresis. This is the first reported case of type I Glanzmann's thrombasthenia in the dog that closely resembles the clinical syndrome and the platelet morphology described in type I Glanzmann's thrombasthenia of human beings.
Band-gap determination by photoreflectance of InGaAs and InAlAs lattice matched to InP (1990)

Photoreflectance-derived band-gap parameters as a function of temperature for InGaAs and InAlAs lattice matched to InP are reported. The experiment was performed on a set of samples of various compositions (and strains) yielding greater reliability and ensuring self-consistency. For InGaAs, fits to the Varshni equation gave E0(T=0 K)=803 meV, α=4.0×10−4 eV K−1, and β=226 K. For InAlAs, E0(T=0 K)=1.541 eV, α=4.7×10−4 eV K−1, β=149 K, and Δ0=338 meV.
P‐39: A Flexible 16kb SRAM based on Low‐Temperature Poly‐Silicon (LTPS) TFT Technology (2006)

Abstract A flexible 16kb SRAM based on low‐temperature poly‐silicon LTPS) TFT technology and surface‐free technology by laser annealing/ablation (SUFTLA®) is presented. The chip consists of approximately 110,000 transistors and occupies an area of about 90mm 2 (10.8mm × 8.3mm). The read access time is 650ns at 3.0V and 200ns at 6.0V.
Phosgene Derivatives. The Preparation of Isocyanates, Carbamyl Chlorides and Cyanuric Acid<sup>1</sup> (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhosgene Derivatives. The Preparation of Isocyanates, Carbamyl Chlorides and Cyanuric Acid1R. J. Slocombe, Edgar E. Hardy, J. H. Saunders, and R. L. JenkinsCite this: J. Am. Chem. Soc. 1950, 72, 5, 1888–1891Publication Date (Print):May 1, 1950Publication History Published online1 May 2002Published inissue 1 May 1950https://pubs.acs.org/doi/10.1021/ja01161a009https://doi.org/10.1021/ja01161a009research-articleACS PublicationsRequest reuse permissionsArticle Views2304Altmetric-Citations56LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
JVM Independent Replay in Java (2005)

Deterministic replay can help to understand the cause of a failing execution of a multi-threaded program. Stepwise browsing of a counterexample serves the same purpose in the context of static and dynamic checking. In this paper we present a tool for deterministic replay of a multi-threaded execution of a Java program. The replay engine is independent of a specific JVM. We also suggest a language to describe thread schedules. Such schedules can be produced either directly by a tool or virtual machine or can, given some additional information, be extracted from a bytecode trace. Thus, off-the-shelf debuggers can be used for both, cyclic debugging of multi-threaded Java programs, and for browsing of concurrent execution traces produced by many checking tools. Experimental results show that correct replay can be performed with acceptable overhead across a number of virtual machines. Plug-ins have been implemented to generate schedules automatically for Java PathFinder and for JNuke.
Using eye-tracking data for high-level user modeling in adaptive interfaces (2007)

In recent years, there has been substantial research on ex-ploring how AI can contribute to Human-Computer In-teraction by enabling an interface to understand a user’s needs and act accordingly. Understanding user needs is especially challenging when it involves assessing the user’s high-level mental states not easily reflected by in-terface actions. In this paper, we present our results on using eye-tracking data to model such mental states dur-ing interaction with adaptive educational software. We then discuss the implications of our research for Intelli-gent User Interfaces. Introduction1 One of the main challenges in devising agents that can act intelligently is to endow them with the capability of un-
A Pulsed, Coaxial Transmission Line Gas Laser (1966)

First Page
Digestive Secretion of <i>Dionaea muscipula</i> (Venus's Flytrap) (1969)

The digestive fluid of Dionaea muscipula has been studied with respect to its protein content as a function of time after entrapment of protein material and some enzymes of the secretion. Maximum secretion of enzyme occurs within the first 3 days of the digestive cycle and protein reaches its maximum at 4 days. Phosphatase, proteinase, nuclease and amylase have been observed in the secretion. The enzymes have acid pH optima and the proteinase has a molecular weight of about 40,000.
Eye Movements in Gaze Interaction (2013)

Gaze as a sole input modality must support complex navigation and selection tasks. Gaze interaction combines specific eye movements and graphic display objects (GDOs). This paper suggests a unifying taxonomy of gaze interaction principles. The taxonomy deals with three types of eye movements: fixations, saccades and smooth pursuits and three types of GDOs: static, dynamic, or absent. This taxonomy is qualified through related research and is the first main contribution of this paper. The second part of the paper offers an experimental exploration of single stroke gaze gestures (SSGG). The main findings suggest (1) that different lengths of SSGG can be used for interaction, (2) that GDOs are not necessary for successful completion, and (3) that SSGG are comparable to dwell time selection.
A multispectral method of determining sea surface temperatures (1972)

A multispectral method for determining sea surface temperatures is discussed. The specifications of the equipment and the atmospheric conditions required for successful multispectral data acquisition are described. Examples of data obtained in the North Atlantic Ocean are presented. The differences between the actual sea surface temperatures and the equivalent blackbody temperatures as determined by a radiometer are plotted.
A 4th-Order Continuous-Time Delta-Sigma Modulator Using 6-bit Double Noise-Shaped Quantizer (2017)

This paper presents a continuous-time delta-sigma modulator using a double noise-shaped quantizer (DNSQ), which not only provides 2nd-order noise shaping but also generates a 6-bit quantization in the modulator. The proposed DNSQ efficiently extracts the quantization error in the time domain from a noise-shaped integrating quantizer (NSIQ), and directly applies it to a gated ring oscillator-based quantizer, hence achieving a 2nd order of noise shaping on its own. By incorporating the DNSQ, the modulator can achieve 4th-order noise shaping with only a 2nd-order loop filter. The proposed modulator is fabricated in a 0.13-μm CMOS process with an active area of 0.17 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . It operates at 640 MHz and achieves a peak SNDR of 80.4 dB in a 15-MHz bandwidth while consuming 11.4 mW from a 1.2-V power supply.
Advances in Prostate Cancer Diagnosis: Triggers for Prostate Biopsy (2016)

In the early years of screening for prostate cancer with serum PSA, absolute cutoffs were typically utilized such as greater than 4.0 ng/mL or even 2.5 ng/mL. A biopsy of the prostate would commonly be recommended in a man with greater than 10-year life expectancy who had a confirmed elevation above such a threshold or in the presence of an abnormal digital rectal examination. The unmet need, however, is to be more selective in recommending a prostate biopsy, due to the risk of complications and the high rate of false-positive PSAs. More recently, various clinical nomograms can be used to refine selection. In addition, clinicians can now utilize various advanced serum biomarkers that have enhanced specificity—especially for the patient with a rising PSA with prior negative biopsy. In this chapter, we will focus on the biomarkers PCA3, Prostate Health Index, and 4 K score to illustrate key concepts in biomarker development and clinical utility.
Relationship between certain physical and chemical properties and subsoil friability in Lemnos loam (1974)

Lemnos loam, a red-brown earth used for fruit production in the Goulburn Valley, Victoria, has degrees of friability in the subsoil as assessed in the field. Forty-one samples from three subsoil depths were obtained from 25 sites near Kyabram. Aggregate stability, as measured in the laboratory was found to be related to field assessments of friability. Exchangeable cations, pH, silt, clay and clay minerals were determined on the samples. By relating some of these measurements to aggregate stability it has been shown that exchangeable Ca++ contributes to a strongly aggregated soil (friable) ; and silt, exchangeable Na+ and exchangeable Mg++ to a weakly aggregated soil (less friable). The effect of silt and exchangeable Na+ is greater than that of exchangeable Ca++ and exchangeable Mg++. A multiple regression equation describing the effect of these four significant factors on stability percentage is presented. This equation accounts for 85.5 per cent of the variation in stability percentage. There is a strong relationship between field assessment of friability and exchangeable Ca++/Mg++ ratio; the higher the ratio, the more friable is the soil.